The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1B8A0-1" ], "evidence": [ { "id": "R-BTA-196950", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196950" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LSG5", "gene_name": "LOC100125266", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1LSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "A0A3Q1LSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ] } ] }, { "uniprot_ac": "A0A3Q1MCB1", "gene_name": "", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1MCB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCB1" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "A0A3Q1MCB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCB1" } ] } ] }, { "uniprot_ac": "A0A3Q1N8V6", "gene_name": "LOC101903026", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] } ] }, { "uniprot_ac": "A0AAA9T5N9", "gene_name": "", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] } ] }, { "uniprot_ac": "A0AAF6Z8C2", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] } ] }, { "uniprot_ac": "A0AAF6Z8S7", "gene_name": "ACP2", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAF6Z8S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8S7" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAF6Z8S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8S7" } ] } ] }, { "uniprot_ac": "A6H730", "gene_name": "ACP3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] } ] }, { "uniprot_ac": "A6H757", "gene_name": "ACP6", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A6H757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H757" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A6H757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H757" } ] }, { "ec_number": "3.1.3.106", "activity": "a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A6H757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H757" } ] }, { "ec_number": "3.1.3.106", "activity": "", "evidence": [ { "id": "A6H757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H757" } ] } ] }, { "uniprot_ac": "E1B8A0", "gene_name": "ACP5", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "E1B8A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8A0" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "E1B8A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8A0" } ] } ] }, { "uniprot_ac": "F1MUZ7", "gene_name": "ACP7", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1MUZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUZ7" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "F1MUZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUZ7" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] } ] }, { "uniprot_ac": "P11064", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5F0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B8A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8A0" }, { "id": "PF00149", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calcineurin-like phosphoesterase", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 249, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "Asn122" } ], "binding_sites": [ { "evidence": [ { "id": "E1B8A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8A0#function" }, { "id": "E1B8A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8A0" }, { "id": "PIRSR000898-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000898-1" } ], "binding_site_uniprot": 116, 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"eco_id": "ECO_0000256", "start_pos": 80, "end_pos": 80, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.2", "ec_name": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "3.1.3.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2" }, { "id": "3.1.3.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.2" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 122 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 153, "end_pos": 155 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": 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"E1B8H0_BOVIN", "mass": { "chemical_mass": 192541.0, "monoisotopic_mass": 192541.0 }, "refseq": { "ac": "XP_003587616", "name": "inactive tyrosine-protein kinase PEAK1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587616" }, "gene_names": [ { "name": "PEAK1", "type": "recommended", "evidence": [ { "id": "E1B8H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ] }, { "name": "PEAK1", "type": "synonym", "evidence": [ { "id": "XP_003587616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587616" } ] } ], "protein_names": [ { "name": "Inactive tyrosine-protein kinase PEAK1", "type": "recommended", "evidence": [ { "id": "E1B8H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8H0/entry#names_and_taxonomy" } ] }, { "name": "Pseudopodium-enriched atypical kinase 1", "type": "synonym", "evidence": [ { "id": "E1B8H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8H0/entry#names_and_taxonomy" } ] }, { "name": "Sugen kinase 269", "type": "synonym", "evidence": [ { "id": "E1B8H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8H0/entry#names_and_taxonomy" } ] }, { "name": "Tyrosine-protein kinase SgK269", "type": "synonym", "evidence": [ { "id": "E1B8H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8H0/entry#names_and_taxonomy" } ] }, { "name": "inactive tyrosine-protein kinase PEAK1", "type": "synonym", "evidence": [ { "id": "XP_003587616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587616" } ] } ], "function": [ { "annotation": "Probable catalytically inactive kinase. 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"url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005145", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "786652", "url": "https://www.ncbi.nlm.nih.gov/gene/786652", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:786652", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:786652", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGWNRNR", "url": "https://omabrowser.org/oma/group/MGWNRNR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B8H0", "url": "https://www.orthodb.org/?gene=E1B8H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22972:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22972:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9013420", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013420", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013424", "url": 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"length": 1747, "header": "tr|E1B8H0-1|E1B8H0_BOVIN Isoform 1 of Inactive tyrosine-protein kinase PEAK1 OS=Bos taurus OX=9913 GN=PEAK1 PE=3 SV=3 CANONICAL=E1B8H0-1" }, "locus": { "chromosome": "21", "start_pos": 32311030, "end_pos": 32245132, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006782.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006782.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006782.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006782.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1079, "start_aa": "Thr", "end_pos": 1079, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1079", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1153, "start_aa": "Thr", "end_pos": 1153, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1153", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1534, "start_aa": "Thr", "end_pos": 1534, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1534", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1545, "start_aa": "Thr", "end_pos": 1545, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1545", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:786652", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:786652", "resource": "KEGG Pathway" }, { "id": "R-BTA-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" }, { "id": "R-BTA-9013424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013424", "resource": "Reactome", "description": "RHOV GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZYR6-1", "protein_name": "Inactive tyrosine-protein kinase PEAK1", "gene_name": "PEAK1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSACNTFTEHVWKPGECKNCFKPKSLHQLPPVSEKKTLSRDNLKTNANQSNSQRGRNTASFRPPVAKKPTIAVKPTMMVADGQGVCGEIGTPDHCENKSVPAGWNRNKAVLHKKPLNNNNEDEIEGYSHVPRPYGSSDGVGKIPNNNNNGLTEVLKEIAGLDTAPQLAGSEMNSRETFLGRINNCYKRSLERKIPPSCMMGGMKDSHSKHVVLSGSTEVISNEGGRFCYPEFSSGDESEDDAFFGSMQEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVQFCVDKKWNTVPLRNKSLQRICAVDYDDSYDEILNGYGEETVILYGQESMQSMVSSDSTSPDSSLTEESRSGTASSSSQKLCNGGLSPSTPQDIKSIEPEYESLCDSQQVKDVSKASRNVPKSLETHKAILALRLEEKDGKIAVQTDKQENKSSSDVSGQAVTINLVPVEEQAKPYRVVNMEQPVCKPYTVVDVSAAMTNECKESQTETSEAKNTSSNPSSPVTPGTPIKSSAASPARVNANLKKSSAIRYQEVWTSSTSPRQKIPKVELVANSSGPSVPPRKTSHKSAPTSPTATNVSSKTIPVKSPNLSEIKFNSYNNAGMPPFPIIIHDEPTYAKSSKNAIKVPIVINPNAYDNLAIYKSFLGTSRELSIKDKTTSVISHTYEEIETENKMSEAIGGKPAEAKGVTNSTECRLGSVAQKVQEFNSCLGKSQRSPQRSHSSDHNSPPRIQKTAQEPADVTPEASAPTGSSSRENASTVLSQIVASIQPPQSPPETPQAGPKSCSAEELYSLPPDADAAKSTLVRPKSLFTSQSEVESSKTTESTAIKLQKDAASQPVATNSPKPVRGTPNATSPKTEQAPPFPPPRSTSSPYHASNLLQRHFSNWAKPNSPTRSTEAESILHSEVRRAADAKPKRWISFKSFFRRRKTDDEEDREKEREKGKLVGLDGTVIHMLPPPPVQRHHWFSEAKSDSSEKPSIVFMYRCEPTQTEPKADHQYKSGVESAIADVLAKDKGETQEKSPESPEQKITSHPSPPQILKKIPSASEHCGINGSPEFQDMIKRLKKALKEFPLMGNCVSEYSGQVPDDTTLEDLSPRVPRAVFVKQDNGGSASVIPVSAVRAPQGEEDKGEAPHPSDLNPCSATYSNLGQSRAAMIPPKQPRQPKGALDDAIAFGGIVDQETMNSLQPTPPPLPKKTILRANTEPSPRDLQKQALENNLCIVANPTYDIDTNWEASSACSSVSLELKALDNESGDSLDRPTEKLRTTTSATNSVSSLTTISIKDRCSNSMESLTGRHLSQSKQSRGVQKPQRQALYRGIENREEVVGKIRSLHADSLKKLALKCEDLFMAGQKDQLRFGVDSWSDFRLTSDKPCCEAGDAVYYPASYAKDPLNHYAVKICKSKAKESQQYYHSLSIRQSLAINFNIQQDCGHFLAEVPVRLLPWEDADAPEVEEEQEEEQEPEQKNGGTPSSTEASQKDSSSNQGTISKPRSRVVVITREVPYLTVADFVRESAPRHAKSPDLYERQVCLLLLQLCLGLEHLKPYHITHCDLRLENLLLVHSRPGGGPLSSESVEPGPSTACPARLIVSNFSQAKQKSHMVDPEVLRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEKEYTHADLPKIPCRSLYSQGLQQLASCLLNPNPSERILISEAKGILQCLLWGPREDLFHALRTSSNPARKDAVLQNWLDIKRTLLMIKFAEKSFDRDCGVILEDWLCCQYLAFATVDSLHRIVRIMQRH", "length": 1787 }, "evidence": [ { "id": "E1B8H0", "url": "https://omabrowser.org/oma/group/E1B8H0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A563-1", "protein_name": "Inactive tyrosine-protein kinase PEAK1", "gene_name": "Peak1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDSEKAPITHGSVKTNANHSNNHRVRNTGNFRPPVAKKPTIAVKPTMMVADGQSVCGELSIQEHCENKPVILGWNQNRTSLSQKPLNNNSEGDTEGFGSVPQQCANNDRAKTIPNNNGLTEVLKEIAGLDASPPVRGNETNSRETFLGRINDCYKRSLERKIPPSCMTGSTKDSQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDVLFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVSKKWNTIPLRNKSLQRICAVDYDDSYDEILNGYEENSGVSYGQGSIQSTVSSDSTSPDSSFTEESRSETASSLSQKICNGGISPGNPGNSKDMAETESNSESPPPNNEEKDSSLTSKSPVKVPETHKAVLALRLQEKDGKIAVQTEKPENKASTDIAGQAVTISLVPVEEQTKPYRVVNLEQPLCKPYTVVDVSAAMASEHLGRPKVKGSSSTPNSPVTSPALTPGQINAHLKKSSAIRYQEVWTSSTSPRQKIPKIELSTGGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNNAGMPPFPIIIHDEPSYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSVISHTYEEIETESKVSDSTPSKLADGPPAKGFSSSAERKRGSVAQKVQEFNNCLNRGQSSPQRSYSSTHSSPAKIQRPTQEPVGKTESAQGSQVPGSSGSTREKASAVLCQIVASIQPPQTPPEAPQSSPKACSVDELYAIPPDADTTKNIPKNTPVRPKSLFTSQSSGEGEAHQTTESPTTKTQKDPSTKPVTSPPSKLVTSTQSEPPPPFPPPRSTSSPYHASNLLQRHFTNWTKPTSPTRSTEAESILHSEGSRRAADAKPKRWISFKSFFRRRKTDEEEEKEKEREKGKLVGLDGTVIHMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPDQGHLSVDQSKAGADNGRTEDVLLRNLEEKKNSHPPSQIPDKACSRVTHEVAEELSPRDPRTPAVKQDGTSVTPTLPPPDLEREEEKDATSDPTDVSPCSATYSNLGQSRAAMIPPKHPRHPKGALDDAIAFGEKTDQEVLNASQPTPPPLPKKMIRANTEPIPKDLQKSMESSLCVVANPTYDIDPNWDASSAGSSVSYELKGLDVESYESLERPLHKERPVPSTANSISSLATLSIKDRFSNSMESLSSRRGLSCRQARSIQKPQRQALYRGLDSREEVVGKLRSLHTDALKRLAVKCEDLFMAGQKDQLRFGVDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLSNYAVKICKSKAKESQQYYHSLAVRQSLPVHFNIQQDCGHFLAEVPNRLLPWEDPNAPEKAEDGNEDSEEEVKAETSGGNPEPCSESESSQKENQQVTNRKQRSHVVVITREVPHLTVADFVRDSLAHHGKSPDLYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVQHQPGGATQCPSPADPCPTSACPTRLIVSNFSQAKQKSHLMDPQILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEKEYTRTDLPRIPLRSPYSWGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQIFTTSATLVQKNALLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSYIVKILQYR", "length": 1733 }, "evidence": [ { "id": "E1B8H0", "url": "https://omabrowser.org/oma/group/E1B8H0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SJ90-1", "protein_name": "Inactive tyrosine-protein kinase PEAK1", "gene_name": "PEAK1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNKTNANHSNNHRIRNTGNFRPPVAKKPTIAVKPTMMVADGQSVCGELSIQENCENKPVIIGWNRNRTALNKKPLNNNNEDDIEGFSHVPKPYDNNDSAKKVSNNNNGLTEVLKEIAGLDTTPQVKGNETNSRETFLGRINDCYKRSLERKLPPSCMMGGIRDTQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDALFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTVPLRNKSLQRICAVDYDDSYDEILNGYEENSVVSYGPGSIQSMVSSDSTSPDSSLTEESRSETASSLSQKVCNGGLSPGNLGDSKDMKESEPNCESPSGNNQEKTSAQASKSSVKVPETHKAVLALRLEEKDGKIAVQTEKQESKASTDIAGQAVTINLVPVEEQAKPYRVVNLEQPLCKPYTVVDVSAAMASEHLEGPVTSPKTKSSSSTPNSPVTSPALTSGQVSAHFQKSSAIRYQEVWTSSTSPRQKIPKVELISGGAGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNNAGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSVISHTYEEIETESKVSDNTTNKPTECPQAKGFSNSTERKRGSVAQKVQEFNSCLNRGQSSPQRSYSSSHSSPTKPQRTTQEPVAKTESTQESQVVSNSSSTREKASTVLSQIVASIQPPQSPPEMPQSGPKACSVEELYAVPPDASVAKSTPKSTPARPKSLFTSQPSSETEAAPQTTESPTTKVQKDPLMKPVTTPPSKLVTNPPNEPPPPFPPPRSTSSPYHASNLLQRHFTNWTKPTSPTRSTEAESVLHSEGSRRAADTKPKRWISFKSFFRRRKTDEEEDKEKDREKGKLVGLDGTVIHMLPPPPVQRHHWFTEAKGESNEKPAIVFMYRCEPAQGQLSVDQGKARAEQSAVTERSGMEDGLLQDSEKKKRSHSSPSQIPKKILSHVTHEVTEDFSPRDPRTVVVKQDGGGCTSVTTALPLPELEREEEKEDISDPMDLNPCSATYSNLGQSRAAMIPPKHPRQPKGALDDAIAFGGKTDQEAPNASQPTPPPLPKKMIIRANTEPISKELQKSLETTLCVMANPTYDIDPNWDASSAGSSISYELKGLDIESYDSLERPLHKERPVPSAANSISSLTTLSIKDRFSNSTESLSSRRGPSCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHADALKKLAIKCEDLFMAGQKDQLRFGVDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQSLAVHFNIQQDCGHFLAEVPKRLLPWEDPDAPGEEEEEMEAAEEVKGETDGENPEPSSEAESSHKESQAVISRKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDTYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTSQGPGPVEPGPTSSCPTRLIVSNFSQAKQKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEKEYTRADLPRIPLRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTASPSPVQRNALLQNWLDIKRTLLMIKFAEKSLDREGGVSLEDWLCAQYLAFATPDSLSCIVKILQPR", "length": 1748 }, "evidence": [ { "id": "E1B8H0", "url": "https://omabrowser.org/oma/group/E1B8H0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q69Z38-1", "protein_name": "Inactive tyrosine-protein kinase PEAK1", "gene_name": "Peak1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDSEKTPITHGSGKTNANHSNNHRVRSTGNFRPPVAKKPTIAVKPTMMVADGQSVCGELSIQEHCENKPVILGWNQNKTSLSQKPLNNNSEGDAEGFGSDPQQCANNDSAQKISNNNNGLTEVLKEIAGLEATPPVRGNETNARETFLGRINDCYKRSLERKIPPSCMTGSMKDSQGKHVILSGSAEVISNEGGRFCYPEFSSGEESEEDVLFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVSKKWNTIPLRNKSLQRICAVDYDDSYDEILNGYEENSGVSYGQGSVQSTISSDCTSPGSSFTEESRSETASSLSQKVCNGGISPGNPGNSKDIAETESNFESPPGNNEEKDESLTSKSSVKVPETHKAVLALRLQEKDGKIAVHTEKPESKASTDIAGQAVTISLVPVEEQTKPYRVVNLEQPLCKPYTVVDVSAAMASEHLGRPKIKGSSSTPNSPVTSPALTPGQINAHLKKSSAIRYQEVWTSSTSPRQKIPKIELSTGGPGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNNAGMPPFPIIIHDEPSYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSVISHTYEEIETESKVSDSTPSKLTDCPQAKGFSNSTERKRGSVAQKVQEFNNCLNRGQSSPQRSYSSTHSSPAKIQRPTQEPAGKTEGAQGSQVPGSSSNSTREKASAVLCQIVASIQPPQTPPEAPQSSPKACSVEELYAVPPDADTTKSIPKNPPVRPKSLFTSQSSGEGEAHQTTESPTAKIQKDPSTKPVTSPPSKLVTSAQSEPPPPFPPPRSTSSPYHASNLLQRHFTNWTKPTSPTRSTEAESILHSEGSRRAADAKPKRWISFKSFFRRRKTDEEEEKEKEREKGKLVGLDGTVIHMLPPPPVQRHHWFTEAKGEASEKPAIVFMYRCDPDQGHLSVDQSKAGAEKGRAEEVLLRNSEEKKSSYLPSQIPDKACSRVTHEVAGELSPRDPRTPAGKQDGTSVTPTLPPPDLEREEEKDDTLDPTDVSPCSATYSNLGQSRAAMIPPKHPRHPKGAVDDAIAFGEKTDQEGLNASQPTPPPLPKKMIRANTEPISKDLQKAMESSLCVMANPTYDIDPNWDASSAGSSISYELKGLDVESYESLERPLHKERPVPSAANSISSLATLSVKDRFSNSMESLSSRRGLSYRQTRSIQKPQRQALYRGLDNREEVVGKLRSLHTDALKRLAVKCEDLFMAGQKDQLRFGVDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLSNYAVKICKSKAKESQQYYHSLAVRQSLPVHFNIQQDCGHFLAEVPSRLLPWEDPDAPEKAEDGTEDSEEEGKAETLGGNPEPCSETEPSQKENQRVTNRKQRSHVVVITREVPHLTVADFVRDSLAHHGNSPDLYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVQHQPGGAAQGPSPADPCPTLACPTRLIVSNFSQAKQKSHLVDPQILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEKEYTRTDLPRIPLRSPYSWGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQIFTTSATLAQKNALLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSYIVKILQYR", "length": 1735 }, "evidence": [ { "id": "E1B8H0", "url": "https://omabrowser.org/oma/group/E1B8H0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H792-1", "protein_name": "Inactive tyrosine-protein kinase PEAK1", "gene_name": "PEAK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGNFRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNNEDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRINDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDVLFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKSLQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSLSQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALRLEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDVSAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTSPRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNNAGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSVISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSPQRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSPPETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTTKVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPTRSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVIHMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRAENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTALSLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKTDQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAGSSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGPSCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFGVDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQSLAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEAASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAKQKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREYTRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTACPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIVKILQHR", "length": 1746 }, "evidence": [ { "id": "E1B8H0", "url": "https://omabrowser.org/oma/group/E1B8H0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of focal adhesion assembly", "id": "GO:0051893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051893", "evidence": [ { "database": "UniProtKB", "id": "E1B8H0", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "E1B8H0", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ], "pmid": "" }, { "name": "regulation of cell motility", "id": "GO:2000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000145", "evidence": [ { "database": "UniProtKB", "id": "E1B8H0", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "E1B8H0", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ], "pmid": "" }, { "name": "focal adhesion assembly", "id": "GO:0048041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048041", "evidence": [ { "database": "UniProtKB", "id": "E1B8H0", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "E1B8H0", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "E1B8H0", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1B8H0", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1B8H0", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "E1B8H0", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "E1B8H0", "url": "https://www.uniprot.org/uniprotkb/E1B8H0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1251, "end_pos": 1253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1556, "end_pos": 1558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 589, "end_pos": 591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 677, "end_pos": 679, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, 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"https://www.ebi.ac.uk/interpro/entry/IPR001377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1B8K9", "url": "https://www.uniprot.org/uniprotkb/E1B8K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8K9-1", "url": "https://www.uniprot.org/uniprotkb/E1B8K9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249, "header": "tr|E1B8K9-1|E1B8K9_BOVIN Isoform 1 of 40S ribosomal protein S6 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=E1B8K9-1" }, "isoforms": [ { "isoform_ac": "E1B8K9-1", "url": "https://www.uniprot.org/uniprotkb/E1B8K9/entry#E1B8K9-1", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249, "header": "tr|E1B8K9-1|E1B8K9_BOVIN Isoform 1 of 40S ribosomal protein S6 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=E1B8K9-1" }, "locus": { "chromosome": "1", "start_pos": 83420325, "end_pos": 83419579, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019214.5", "url": "https://www.ensembl.org/id/ENSBTAT00000019214.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019214.3", "url": "https://www.ensembl.org/id/ENSBTAP00000019214.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "E1B8K9", "url": "https://omabrowser.org/oma/group/E1B8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "E1B8K9", "url": "https://www.uniprot.org/uniprotkb/E1B8K9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "E1B8K9", "url": "https://www.uniprot.org/uniprotkb/E1B8K9" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "E1B8K9", "url": "https://www.uniprot.org/uniprotkb/E1B8K9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "E1B8K9", "url": "https://www.uniprot.org/uniprotkb/E1B8K9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B8K9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 249, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B8K9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B8K9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], 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"pathway": [ { "id": "bta:511340", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511340", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9PF81-1", "protein_name": "Tumor protein p53-inducible nuclear protein 2 isoform X1", "gene_name": "tp53inp2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFQALSSLFFGSVDDVTPELKGPKPCVTEADEEGWLLVNLPGEDGPEAASVACARPRSECHASPPTCKNRRSRAGRTQATPPLSTCSAPDPASFSHLESVEVNVLLSERGSCSCSDCSMDESWFVTPPPCFTAEGATAEASPMEDLLIEHPSMSVYVSPGPLPAMEESATSLAGSISRMSESALPAVTRSSLPTRVTRGAAAQAGALAKVTQVSRVQRAKARTERRHLGRNRMQRQNRVREQVQRRATHTRNSFLHQPCQRNICH", "length": 265 }, "evidence": [ { "id": "E1B8N8", "url": "https://omabrowser.org/oma/group/E1B8N8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HAP3-1", "protein_name": "Tumor protein p53-inducible nuclear protein 2 isoform X1", "gene_name": "Tp53inp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFQRFTSLFFSTPSPPEDSNCPGAFVSEEDEVDGWLIIGLQDSYTAPPNPGASPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSNPLEDLLIEHPSMSVYVTGSTIVLESGPPSPHPDAVLPEEDLSDGELAPARREPRALHHAAAAALPARAALLEKAGQVRRLQRARQRAERHALSAKVLQRQNRARESRSRKPKHQGSFIYQPCQRQFNY", "length": 222 }, "evidence": [ { "id": "E1B8N8", "url": "https://omabrowser.org/oma/group/E1B8N8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LVN2-1", "protein_name": "Tumor protein p53 inducible nuclear protein 2", "gene_name": "TP53INP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFQRFTSLFFSTPAPPEDPNCPRAFVSEEDEVDGWLIIDLPDSFTASPSPGAAPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGPPSPHPDAALPDGNLSDGELAPAHREPRALHHAAAPLPARAALLEKAGQARRLQRARQRAERHALSAKVVQRQNRARESRPRRPKHQGSFVYQPCQRQFNY", "length": 221 }, "evidence": [ { "id": "E1B8N8", "url": "https://omabrowser.org/oma/group/E1B8N8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8CFU8-1", "protein_name": "Tumor protein p53-inducible nuclear protein 2", "gene_name": "Tp53inp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQRFTSLFFNTPAPPEDSNCPGAFVSEEDEVDGWLIIDLQDSYTAPPDPGASPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSNPLEDLLIEHPSMSVYVTGSTIVLESGPPSPHPEAALPDQDLSDGELAPALREPRALHHAAAPMPARAVLLEKAGQVRRLQRARQRAERHTLSAKVLQRQNRARESRSRRPKHQGSFIYQPCQRQFNY", "length": 221 }, "evidence": [ { "id": "E1B8N8", "url": "https://omabrowser.org/oma/group/E1B8N8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CHM3-1", "protein_name": "Tumor protein p53-inducible nuclear protein 2", "gene_name": "Tp53inp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQRFTSLFFSTPAPPEDSNCPGAFVSEEDEVDGWLIIDLQDSYTAPPDPRASPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSNPLEDLLIEHPSMSVYVTGSTIVLESGPPSPHPEAALPDQDLSDGELAPARREPRALHHAAAPMPARAVLLEKAGQVRRLQRARQRAERHTLSAKVLQRQNRARES", "length": 199 }, "evidence": [ { "id": "E1B8N8", "url": "https://omabrowser.org/oma/group/E1B8N8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IXH6-1", "protein_name": "Tumor protein p53-inducible nuclear protein 2", "gene_name": "TP53INP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFQRLSSLFFSTPSPPEDPDCPRAFVSEEDEVDGWLIIDLPDSYAAPPSPGAAPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAARHAAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRRSKNQSSFIYQPCQRQFNY", "length": 220 }, "evidence": [ { "id": "E1B8N8", "url": "https://omabrowser.org/oma/group/E1B8N8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "E1B8N8", "url": "https://www.uniprot.org/uniprotkb/E1B8N8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1B8N8", "url": "https://www.uniprot.org/uniprotkb/E1B8N8" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E1B8N8", "url": "https://www.uniprot.org/uniprotkb/E1B8N8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1B8N8", "url": "https://www.uniprot.org/uniprotkb/E1B8N8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1B8N8", "url": "https://www.uniprot.org/uniprotkb/E1B8N8" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "E1B8N8", "url": "https://www.uniprot.org/uniprotkb/E1B8N8" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "E1B8N8", "url": "https://www.uniprot.org/uniprotkb/E1B8N8" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "E1B8N8", "url": "https://www.uniprot.org/uniprotkb/E1B8N8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B8N8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 224, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B8N8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B8N8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1B8Q8-1", "uniprot_ac": "E1B8Q8", "uniprot_id": "E1B8Q8_BOVIN", "mass": { "chemical_mass": 113248.0, "monoisotopic_mass": 113248.0 }, "refseq": {}, "gene_names": [ { "name": "XPOT", "type": "recommended", "evidence": [ { "id": "E1B8Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8" } ] } ], "protein_names": [ { "name": "Exportin-T", "type": "recommended", "evidence": [ { "id": "E1B8Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8/entry#names_and_taxonomy" } ] }, { "name": "Exportin(tRNA)", "type": "synonym", "evidence": [ { "id": "E1B8Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8/entry#names_and_taxonomy" } ] }, { "name": "tRNA exportin", "type": "synonym", "evidence": [ { "id": "E1B8Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mediates the nuclear export of aminoacylated tRNAs. In the nucleus binds to tRNA and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the tRNA from the export receptor. XPOT then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.", "evidence": [ { "database": "UniProtKB", "id": "E1B8Q8", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8#function" }, { "database": "UniProtKB", "id": "ARBA00056097", "url": "https://www.uniprot.org/uniprotkb/ARBA00056097#function" } ] }, { "annotation": "tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.", "evidence": [ { "database": "UniProtKB", "id": "E1B8Q8", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8#function" }, { "database": "UniProtKB", "id": "RU366037", "url": "https://www.uniprot.org/uniprotkb/RU366037#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B8Q8", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "XPOT", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8", "locus": { "chromosome": "5", "start_pos": 49320231, "end_pos": 49360821, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000026962", "url": "https://www.ensembl.org/id/ENSBTAG00000026962" } ] } } ], "crossref": [ { "id": "E1B8Q8", "url": "https://alphafold.ebi.ac.uk/entry/E1B8Q8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000026962", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000026962", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1B8Q8", "url": "https://www.orthodb.org/?gene=E1B8Q8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15952:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15952:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19282", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19282", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1B8Q8", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8Q8-1", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLERDVCGFFCGIRGHAYCNQKTPSIAAGMDEQALLGLNPNADSDFRQRALAYFEQLKISPDAWQVCAEALAQRTYSDDHIKFFCFQVLEHQVKYKYSELTTVQQQLIRETLVSWLQAQMLNPQPEKTFIRNKAAQVFALLFVTEYLTKWPKFFFDILSVVDLNPRGVDLYLRILMAIDSELVDRDVVHTSEEARRNTLIKDTMREQCIPNLVESWYQILQNYQYTNSEVTCQCLEVVGAYVSWIDLSLIANDRFINMLLGHMSIEVLREEACDCLFEIVNKGMDPVDKMKLVESLCQVLQSAGFFSIDREEDVDFLARFSKLVNGMGQSLIVSWTKLIKNGDIKNAQEALQAIETKVALMLQLLIHEDDDISSNIIGFCYDYLHILKQLTVLSDRQKANVETIMLAVMKKLTYDEEYNFENEGEDEAMFVEYRKQLKLLLDRLAQVSPELLLASVRRVFSSTLQNWQTTRFMEVEVAIRLLYMLAEALPVSHGAHFSGDVSKASALQDMMRTLVTSGVSSYQHTSVTLEFFETVVRYEKFFTVEPQHIPCVLMAFLDHRGLRHSSAKVRSRTAYLFSRFVKSLNKQMNPFIEDILNRIQDLLELSPPENGYQSLLSSDDQLFIYETAGVLIVNSEYPAERKQALMRNLLTPLMEKFKILLEKLMLAQDEERQASLADCLNHAVGFASRTSKAFSNKQTVKQCGCSEVYLDCLQTFLPALSCPLQKDILRSGVRTFLHRMIICLEEEVLPFIPSASEHMLKDCEAKDLQEFIPLINQITAKFKIQVSPFLQQMFMPLLHAIFEVLLRPAEENDQSAALEKQMLRRSYFAFLQTVTGSGMSEVIANQGAENVERVLVTVIQGAVEYPDPIAQKTCFIILSKLVELWGGKDGPVGFADFVYKHIVPACFLAPLKQTFDLADAQTVLALSECAVTLKTIHLKRGPECVQYLQQEYLPSLQVAPEIIQEFCQALQQPDAKVFKNYLKVFFQRAKP", "length": 991, "header": "tr|E1B8Q8-1|E1B8Q8_BOVIN Isoform 1 of Exportin-T OS=Bos taurus OX=9913 GN=XPOT PE=3 SV=4 CANONICAL=E1B8Q8-1" }, "isoforms": [ { "isoform_ac": "E1B8Q8-1", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8/entry#E1B8Q8-1", "sequence": { "sequence": "MLERDVCGFFCGIRGHAYCNQKTPSIAAGMDEQALLGLNPNADSDFRQRALAYFEQLKISPDAWQVCAEALAQRTYSDDHIKFFCFQVLEHQVKYKYSELTTVQQQLIRETLVSWLQAQMLNPQPEKTFIRNKAAQVFALLFVTEYLTKWPKFFFDILSVVDLNPRGVDLYLRILMAIDSELVDRDVVHTSEEARRNTLIKDTMREQCIPNLVESWYQILQNYQYTNSEVTCQCLEVVGAYVSWIDLSLIANDRFINMLLGHMSIEVLREEACDCLFEIVNKGMDPVDKMKLVESLCQVLQSAGFFSIDREEDVDFLARFSKLVNGMGQSLIVSWTKLIKNGDIKNAQEALQAIETKVALMLQLLIHEDDDISSNIIGFCYDYLHILKQLTVLSDRQKANVETIMLAVMKKLTYDEEYNFENEGEDEAMFVEYRKQLKLLLDRLAQVSPELLLASVRRVFSSTLQNWQTTRFMEVEVAIRLLYMLAEALPVSHGAHFSGDVSKASALQDMMRTLVTSGVSSYQHTSVTLEFFETVVRYEKFFTVEPQHIPCVLMAFLDHRGLRHSSAKVRSRTAYLFSRFVKSLNKQMNPFIEDILNRIQDLLELSPPENGYQSLLSSDDQLFIYETAGVLIVNSEYPAERKQALMRNLLTPLMEKFKILLEKLMLAQDEERQASLADCLNHAVGFASRTSKAFSNKQTVKQCGCSEVYLDCLQTFLPALSCPLQKDILRSGVRTFLHRMIICLEEEVLPFIPSASEHMLKDCEAKDLQEFIPLINQITAKFKIQVSPFLQQMFMPLLHAIFEVLLRPAEENDQSAALEKQMLRRSYFAFLQTVTGSGMSEVIANQGAENVERVLVTVIQGAVEYPDPIAQKTCFIILSKLVELWGGKDGPVGFADFVYKHIVPACFLAPLKQTFDLADAQTVLALSECAVTLKTIHLKRGPECVQYLQQEYLPSLQVAPEIIQEFCQALQQPDAKVFKNYLKVFFQRAKP", "length": 991, "header": "tr|E1B8Q8-1|E1B8Q8_BOVIN Isoform 1 of Exportin-T OS=Bos taurus OX=9913 GN=XPOT PE=3 SV=4 CANONICAL=E1B8Q8-1" }, "locus": { "chromosome": "5", "start_pos": 49360622, "end_pos": 49320851, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038585.6", "url": "https://www.ensembl.org/id/ENSBTAT00000038585.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038398.6", "url": "https://www.ensembl.org/id/ENSBTAP00000038398.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA re-export from nucleus", "id": "GO:0071528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071528", "evidence": [ { "database": "UniProtKB", "id": "E1B8Q8", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "E1B8Q8", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "E1B8Q8", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1B8Q8", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1B8Q8", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "E1B8Q8", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "E1B8Q8", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B8Q8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 991, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B8Q8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B8Q8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B8Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8Q8" }, { "id": "SM00913", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00913" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Importin N-terminal", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 118, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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}, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1B8R4-1", "uniprot_ac": "E1B8R4", "uniprot_id": "E1B8R4_BOVIN", "mass": { "chemical_mass": 89338.0, "monoisotopic_mass": 89338.0 }, "refseq": { "ac": "XP_015327030", "name": "probable G-protein coupled receptor 156 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015327030" }, "gene_names": [ { "name": "GPR156", "type": "recommended", "evidence": [ { "id": "E1B8R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R4" } ] }, { "name": "GPR156", "type": "synonym", "evidence": [ { "id": "XP_015327030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015327030" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 156", "type": "synonym", "evidence": [ { "id": "E1B8R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R4/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 156 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015327030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015327030" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B8R4", "url": "https://www.uniprot.org/uniprotkb/E1B8R4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPR156", "url": "https://www.uniprot.org/uniprotkb/E1B8R4", "locus": { "chromosome": "1", "start_pos": 64938751, "end_pos": 65018783, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001464", "url": "https://www.ensembl.org/id/ENSBTAG00000001464" } ] } } ], "crossref": [ { "id": "E1B8R4", "url": "https://alphafold.ebi.ac.uk/entry/E1B8R4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001464", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001464", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15292", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15292", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539186", "url": "https://www.ncbi.nlm.nih.gov/gene/539186", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "THFCASQ", "url": "https://omabrowser.org/oma/group/THFCASQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B8R4", "url": "https://www.orthodb.org/?gene=E1B8R4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10519", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10519", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10519:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10519:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015327030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015327030", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1B8R4", "url": "https://www.uniprot.org/uniprotkb/E1B8R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8R4-1", "url": "https://www.uniprot.org/uniprotkb/E1B8R4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRHIPRGAYDDMEPEINCSELCDGFSGQELERRPLHDLCRTTITSSHHSSKTISSLSPALLGIVWTFLSCGLLLIAFFLGFTIRCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIHNQGALVGSSMESLIQIRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDKRVIIKDLQLLELVAALVIADVILLMTWVLTDPIQCLQILGVSMTVTGRDVSCSLTSTHFCASRYSDVWIALILGCKGLLLLYGAYLAGLTDHVSSPPVNQSLTIMVGVNLVVLAAGLLFVVTRYLYSWPNLVFGLTSGGIFVCTTTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTPSKSLHTQYGEEQNCHIRGEKNSMERLLTEKNAVIESLQEQVNNAREKLVRLMSAGCSSDLPEEAVPPASSHHKDILATASAHSLAPQGPSECLSDSQNDTSAATQDSQSTSVLASSVQGLRGPVKDTSPSTGQKKKISDLKDLSNPLHLGCSQKPWAEQSQTAERRDQVPMALHQCLMQSEEGSVPQRHGQVENSEGSPEQLGSRVNSVIREKLQEVLQDLGLGPRAPLPSSLSCPQQPWKSITAHSPQKVPLSKEPGFSPSMVRRRRAAQRARSNFLGAVPSYVGHRVNRAISGQNVQDSPCLDPQTADPRVARPSSGNPLVLPAPQGKPGALEGHTQRQAEPRGAERSLESFPQKSSGSGRKLCPAAPRPSRASPDLPGQRQPPGSPGCPSLSSPSSYLDTESSSSDELFCRCHRPYCEICFQSSSDSSDSGSSDTDPEPAGALASWEKLWARSKPIVNFKDDLKPTLV", "length": 820, "header": "tr|E1B8R4-1|E1B8R4_BOVIN Isoform 1 of G protein-coupled receptor 156 OS=Bos taurus OX=9913 GN=GPR156 PE=3 SV=3 CANONICAL=E1B8R4-1" }, "isoforms": [ { "isoform_ac": "E1B8R4-1", "url": "https://www.uniprot.org/uniprotkb/E1B8R4/entry#E1B8R4-1", "sequence": { "sequence": "MNRHIPRGAYDDMEPEINCSELCDGFSGQELERRPLHDLCRTTITSSHHSSKTISSLSPALLGIVWTFLSCGLLLIAFFLGFTIRCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIHNQGALVGSSMESLIQIRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDKRVIIKDLQLLELVAALVIADVILLMTWVLTDPIQCLQILGVSMTVTGRDVSCSLTSTHFCASRYSDVWIALILGCKGLLLLYGAYLAGLTDHVSSPPVNQSLTIMVGVNLVVLAAGLLFVVTRYLYSWPNLVFGLTSGGIFVCTTTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTPSKSLHTQYGEEQNCHIRGEKNSMERLLTEKNAVIESLQEQVNNAREKLVRLMSAGCSSDLPEEAVPPASSHHKDILATASAHSLAPQGPSECLSDSQNDTSAATQDSQSTSVLASSVQGLRGPVKDTSPSTGQKKKISDLKDLSNPLHLGCSQKPWAEQSQTAERRDQVPMALHQCLMQSEEGSVPQRHGQVENSEGSPEQLGSRVNSVIREKLQEVLQDLGLGPRAPLPSSLSCPQQPWKSITAHSPQKVPLSKEPGFSPSMVRRRRAAQRARSNFLGAVPSYVGHRVNRAISGQNVQDSPCLDPQTADPRVARPSSGNPLVLPAPQGKPGALEGHTQRQAEPRGAERSLESFPQKSSGSGRKLCPAAPRPSRASPDLPGQRQPPGSPGCPSLSSPSSYLDTESSSSDELFCRCHRPYCEICFQSSSDSSDSGSSDTDPEPAGALASWEKLWARSKPIVNFKDDLKPTLV", "length": 820, "header": "tr|E1B8R4-1|E1B8R4_BOVIN Isoform 1 of G protein-coupled receptor 156 OS=Bos taurus OX=9913 GN=GPR156 PE=3 SV=3 CANONICAL=E1B8R4-1" }, "locus": { "chromosome": "1", "start_pos": 65018584, "end_pos": 64939755, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001918.6", "url": "https://www.ensembl.org/id/ENSBTAT00000001918.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001918.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001918.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A8Y6-1", "protein_name": "G protein-coupled receptor 156", "gene_name": "GPR156", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MELGFNCSDLCDGQPGFGNQEQQQRMLQELCTVTITSSDRSGKSSPSFSAALLGVVWTFLTGGVLLALFFLVFTIRFRKNRIVKMSSPNLNVVTLLGSGLTYTSAYLFGIQEQSLESSGKSVEMLIQLRLCLLCVGTSLVLGPILGKSWRLYKVFTQRVPDKRVIIKDLQLLVMVVVLVLADAVLLFTWVFSDPIQCFRSLSVSLRATEKGMTCSVSRMQSCASLYSDLWLVLILGFKSVLLLYGTYLAGLTDSVSSPPVNQSLTLIVGVNLIFLVAGTVVLIHRFFRAWHNLLFGFTSGGIFVCTTTINCFIFVPQLRQWKTFEEENQTLSHMAKYFSSPSRSYHSVYSEEQLYQLIGEKNSMKQLLTEKNAVIESLQEQVNNAKEKLMRLMSAEGGCSPAVPNPCAQSTGQHCEKCSSAGDVPREHWPLDTEKDGQQTSSVLCALPHCPVPLSSDAQDLWKHVSHERELTEEPECSPTLLFDMGGSLECSPEHAQECGMLAGKHPLEQDASAGVAGEHPPKVSYVSSEKLQEVLQELSLDSRTCSPAFPSHTGRMWGTQEGHPAIRSSLSPYLTRRRRRVLLPPTSTGLPASSRAWCTAGSRPGTRSHGEPAGLGPGKESEGAGRGLPQPSLSSPSIPAKGWPGLRGWAVSGTELEGRRNTSLQDWRQQSSLGVPARPILHSLYHYPDSDSSSSSEEVFPCCHRPCCQLCLQSPRGSLGSSSSSSTETDMEPGGAVGCWLEPQGKTQPVVNFKEDLKPTFV", "length": 763 }, "evidence": [ { "id": "E1B8R4", "url": "https://omabrowser.org/oma/group/E1B8R4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SPD3-1", "protein_name": "G protein-coupled receptor 156", "gene_name": "GPR156", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPEINCSELCDGFPGQELERRPLHELCRTTITSSHHSTKTISSLSPALLGIVWTFLSCGLLLIAFFLGFTIRCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIQDKGSLAGSSMETLIQVRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDKRVIIKDLQLLGLVAALVIADVILLMTWVLTDPIQCLQILSVSMTVTGRDVSCSLTSTHFCASQYSDVWIALALGCKGLLLLYGAYLAGLTDHVSSPPVNQSLTIMVGVNLVVLAAGLLFVVTRYLHSWPNLVFGLTSGGIFVCTTTVNCFIFIPQLKQWKAFEEENQTIRRMAKYFSTPSKSLHTQYGEEQKCHVRGEKNSMERLLTEKNAVIESLQEQVNNAKEKLVRLMSAECPYDPPEGAVPPAASHSKDALAAASPPVLAAQGPSECPSDSQNDTRAATRDSRSISVPSLGVQSFRGPEKDTSPSPGQKEKISGLKDFSDHLSLGCSQKPRAEQSQGAERKEQGPVTLHQNRMPCGEGSVSQRQGQLGNSEEPQEPLARVNAVIREKLQEVLQDLGLNPEAPLPPSCPQQLWKGSAAHSPQKMPLSKELGLSPYLVRRRRAAQRARAHFPGSAPSYVGHRVNRTVSGTHSGLSVQDRDSSCLNPQTADSRVPRPSSGKPLLLPDPPGKPGSQEGSKKRQTEPPGAEGSCPAFPHLPSGSGRALCPATPGLSGASPDLPEQRQWQSPGSPGCLSLSSPCSYLDTESSSSDEFFCRCHRPYCEICFQSSSDSSDSGSSDSDPEPTEGLASWEKLWTRSKPIVNFKDDLKPTLV", "length": 813 }, "evidence": [ { "id": "E1B8R4", "url": "https://omabrowser.org/oma/group/E1B8R4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6PCP7-1", "protein_name": "Probable G protein-coupled receptor 156", "gene_name": "Gpr156", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPEINCSEFCDSFPGQELDRRPLHDLCKTTITESQHSSTAASPLSPALLGIMWTFLSCGLLLVLFFLAFTIRCRKNRIVKMSSPNLNVVTLLGSCLTYISAYLFGIQDALEGSSVEALIQTRLSLLCIGTSLVFGPILGKSWRLYKVFTQRVPDKRVIIKDLQLLGLVAALVVADVILLVTWVLTDPIQCLQMLGVSMKVTGRDVSCSLTNTHFCASRYSDVWIALVLGCKGLLLLYGAYLAGLTNHVSSPPVNQSLTIMVGVNLLLLTAGLLFVVTRYLHSWPNLVFGLTSGGIFVCTTTVNCCVFIPQLKQWKAFEGENQTMRHMAKYFSTPSKSFHSQFDEDPSCHLRDEKSCMERLLTEKNAVIESLQEQVSNAKEKLVKLMSAECTYDSPEWAVPDAASARGLALPGPSECPAVSENESGAAARDSLHVPAACQHVQGPGASRRDTSPSPAQQDNMPLKQYCDHLDTGCNQKPKAEQSEGPERGDQEPMAPSQRLMADGVACEPHKPRQSPEGLPKKLPGVSSVVREKLQEVLQELDLGSEAPLSPLPCPQQLWKSTTSRSPQKLSPSKLGFSPYVVRRRRAAQRARSHIPGSVGLNVGHQANSTVSSSQSGLIVQNRDSPRLDHHNARSKVPRSSSVKPSPLSEPRRKQGTLEGSKQCETEPQEAGGACNVAFPCQSSASVQAQSPAAPCLPSSPALPRQRQPRPRLSPGCPSLSSGCYNLDSESSSSDEFFCRCHRPYCEICFQSSLDSNDSDTSDSDLEQASGLASWEKLWARSKPVVNFKDDLKPTLV", "length": 798 }, "evidence": [ { "id": "E1B8R4", "url": "https://omabrowser.org/oma/group/E1B8R4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K451-1", "protein_name": "Probable G protein-coupled receptor 156", "gene_name": "Gpr156", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPEINCSEFCDSFPGQELDRRPLHDLCKTTITDSQHGSADISPLSPALLGVIWTFLSCGLLLVLFFLAFTIRCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIQDALVGSSVEALIQTRLSLLCIGTTLVFGPILGKSWRLYKVFTQRVPDKRVIIKDLQLLGLVAALVVADVILLVTWVLTDPIQCLQILGVSMKVTGRDVSCSLTNTHFCASRYSDVWIALVLGCKGLLLLYGAYLAGLTNHVSSPPVNQSLTIMVGVNLLLLTAGLLFVVTRYLHSWPNLVFGLTSGGIFVCTTTVNCCVFLPQLRQRKAFEGENQTIRHMAKYFSTPSKTFRSKFDEDQSCHLRDEXSCMERLLTEKNAVIESLQEQVSNAKEKLVKLMSAECALDSPEWAVPAAASAGGPAECXATSEKESGAAAEDSLPASAASQHMQGPGASRRDXSPSPDQKYDMPLKQFCDHLDMGCSQKPKAEQSEGPERGNQEPMAPGQSLMTDGVACEPHRPRQNSEVLPERLPRVSSVVREKLQEVLQELDLGTEAPLSPLPCPQQPWKSNTSGSPQKLSPSKLGFSPYVVRRRRAAQRARSRIPGSVGLKMGHQANNTVSGSQNGLIVQNRDSPRLDHHNARSKEPRSSSVKPSPISAPHQRRGSLEGSKQCETEPQEARGYSVAFPRQPSASAPAQSSTAPCLSSXPALPRQRQPLPLLSPGCPSLSSGCYNLDSESSSSDEFFCRCHRPYCEICFQSSLDSNDSDTSDSDLEQTSGLASWEKLLARSKPVVNFKDDLKPTLV", "length": 792 }, "evidence": [ { "id": "E1B8R4", "url": "https://omabrowser.org/oma/group/E1B8R4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NFN8-1", "protein_name": "Probable G protein-coupled receptor 156", "gene_name": "GPR156", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPEINCSELCDSFPGQELDRRPLHDLCKTTITSSHHSSKTISSLSPVLLGIVWTFLSCGLLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIQDVLVGSSMETLIQTRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDKRVIIKDLQLLGLVAALLMADVILLMTWVLTDPIQCLQILSVSMTVTGKDVSCTSTSTHFCASRYSDVWIALIWGCKGLLLLYGAYLAGLTGHVSSPPVNQSLTIMVGVNLLVLAAGLLFVVTRYLHSWPNLVFGLTSGGIFVCTTTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTPNKSFHTQYGEEENCHPRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDLPEGAAPPASSPNKDVQAVASVHTLAAAQGPSGHLSDFQNDPGMAARDSQCTSGPSSYAQSLEGPGKDSSFSPGKEEKISDSKDFSDHLDSGCSQKPWTEQSLGPERGDQVPMNPSQSLLPERGGSDPQRQRHLENSEEPPERRSRVSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVRRRRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRVRRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKASPDLPEQWQLWPPVPSGCASLSSQHSYFDTESSSSDEFFCRCHRPYCEICFQSSSDSSDSGTSDTDPEPTGGLASWEKLWARSKPIVNFKDDLKPTLV", "length": 814 }, "evidence": [ { "id": "E1B8R4", "url": "https://omabrowser.org/oma/group/E1B8R4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "gamma-aminobutyric acid signaling pathway", "id": "GO:0007214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007214", "evidence": [ { "database": "UniProtKB", "id": "E1B8R4", "url": "https://www.uniprot.org/uniprotkb/E1B8R4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled GABA receptor activity", "id": "GO:0004965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004965", "evidence": [ { "database": "UniProtKB", "id": "E1B8R4", "url": "https://www.uniprot.org/uniprotkb/E1B8R4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor heterodimeric complex", "id": "GO:0038039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038039", "evidence": [ { "database": "UniProtKB", "id": "E1B8R4", "url": "https://www.uniprot.org/uniprotkb/E1B8R4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B8R4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 820, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B8R4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B8R4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B8R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R4" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 326, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 447, "end_pos": 449 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1B8S3-1", "uniprot_ac": "E1B8S3", "uniprot_id": "E1B8S3_BOVIN", "mass": { "chemical_mass": 134603.0, "monoisotopic_mass": 134603.0 }, "refseq": { "ac": "NP_001179415", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 18", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179415" }, "gene_names": [ { "name": "ADAMTS18", "type": "recommended", "evidence": [ { "id": "E1B8S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8S3" } ] }, { "name": "ADAMTS18", "type": "synonym", "evidence": [ { "id": "NP_001179415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179415" } ] } ], "protein_names": [ { "name": "A disintegrin and metalloproteinase with thrombospondin motifs 18", "type": "recommended", "evidence": [ { "id": "E1B8S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8S3/entry#names_and_taxonomy" } ] }, { "name": "A disintegrin and metalloproteinase with thrombospondin motifs 18", "type": "synonym", "evidence": [ { "id": "NP_001179415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179415" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B8S3", "url": "https://www.uniprot.org/uniprotkb/E1B8S3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADAMTS18", "url": "https://www.uniprot.org/uniprotkb/E1B8S3", "locus": { "chromosome": "18", "start_pos": 4521897, "end_pos": 4667696, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001010", "url": "https://www.ensembl.org/id/ENSBTAG00000001010" } ] } } ], "crossref": [ { "id": "E1B8S3", "url": "https://alphafold.ebi.ac.uk/entry/E1B8S3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001010", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001010", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "518395", "url": "https://www.ncbi.nlm.nih.gov/gene/518395", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:518395", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518395", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICELVGC", "url": "https://omabrowser.org/oma/group/ICELVGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B8S3", "url": "https://www.orthodb.org/?gene=E1B8S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179415", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179415", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1B8S3", "url": "https://www.uniprot.org/uniprotkb/E1B8S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8S3-1", "url": "https://www.uniprot.org/uniprotkb/E1B8S3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MECALLLACALPAARSGPPWGPAARGRVAKALQLCCLCCASVAAALASDSRGGEGSGLNHDYVFVTPVEVDSGGSYISHDILHNGRKKRSAQSASSSLHYRFSAFGQELHLELKPSAILSSHFIVQVLGKDGASETREPAVPRCFYQGFIRNDSSSSVAVSTCAGLTGLIRTQKNEFLISPLPQLLAQEHNYSSPAGHHPHVLYKRTAEEKIRRCHGYLSSGRNPAGHPPSHTPHTSWSPEREQHHGRLQKQHFCGRRKKYAPKPPTEDTYLRFDEYGSSGRPRRSAGKSQKGLNVETLVVADKKMVEKHGKANVTTYILTVMNMVSSLFKDGTIGSDINIVVVSLILLEQEPGGLLINHHADQSLNSFCQWQSALVGKNGKRHDHAILLTGFDICSWKNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMVHDGEGNPCRKTEGNIMSPTLTGNNGVFSWSSCSRQYLKKFLSTPQAGCLVDEPKQTGQYKYPDKLPGQMYDADTQCKWQFGAKAKLCGLGLVKDICKSLWCHRVGHRCETKFMPAAEGTVCGLSMWCRQGQCVKLGDLGPRPIHGQWSAWSKWSECSRTCGGGVRYQERHCNNPKPQYGGKFCPGSSRVYQLCNINPCDKNSLDFRAQQCAEYNSKPFRGWFYQWKPYMKVEEEDRCKLYCKAENFEFFFAMSSKVKDGTPCSPNKNDVCIDGICEPVGCDHELGSKAVSDACGVCKGDNSTCKFYKGLYLNQHKANEYYPVVTIPAGARSVEVQELQVSSSYLAVRSLGHKYYLTGGWSVDWPGEFAFAGTVFEYQRAFNRPECLSAPGPINETLVFEILMQGKNPGIAWKYALPKVTNGTLPASKRHSYAWSTVQTDCSVSCGGGYISVKAVCLRDQNTQVNSSFCNARARPATEPKMCNAFSCPAYWKPGEWSACSRSCAGGQQSRKVQCVQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPPEWSPGPWSQCSKTCGRGVRKREVTCRRAAVAEAVPESACAGAARPDSQEGCVLGRCPKNSRLQWLISSWSECSVSCGLGVRKREMKCSEKAFQGKLITLPERRCRNIKKPNVDLEETCSRGACPAHPVYSLAAGWYSSPWQQCTVSCGGGVQTRSVHCVQQGRPSSSCLLRQKPPVLRACNTNFCPAPAKREDPSCVDFFGWCRLVPQHGVCNHKFYGKQCCRSCSRKS", "length": 1223, "header": "tr|E1B8S3-1|E1B8S3_BOVIN Isoform 1 of A disintegrin and metalloproteinase with thrombospondin motifs 18 OS=Bos taurus OX=9913 GN=ADAMTS18 PE=4 SV=3 CANONICAL=E1B8S3-1" }, "isoforms": [ { "isoform_ac": "E1B8S3-1", "url": "https://www.uniprot.org/uniprotkb/E1B8S3/entry#E1B8S3-1", "sequence": { "sequence": "MECALLLACALPAARSGPPWGPAARGRVAKALQLCCLCCASVAAALASDSRGGEGSGLNHDYVFVTPVEVDSGGSYISHDILHNGRKKRSAQSASSSLHYRFSAFGQELHLELKPSAILSSHFIVQVLGKDGASETREPAVPRCFYQGFIRNDSSSSVAVSTCAGLTGLIRTQKNEFLISPLPQLLAQEHNYSSPAGHHPHVLYKRTAEEKIRRCHGYLSSGRNPAGHPPSHTPHTSWSPEREQHHGRLQKQHFCGRRKKYAPKPPTEDTYLRFDEYGSSGRPRRSAGKSQKGLNVETLVVADKKMVEKHGKANVTTYILTVMNMVSSLFKDGTIGSDINIVVVSLILLEQEPGGLLINHHADQSLNSFCQWQSALVGKNGKRHDHAILLTGFDICSWKNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMVHDGEGNPCRKTEGNIMSPTLTGNNGVFSWSSCSRQYLKKFLSTPQAGCLVDEPKQTGQYKYPDKLPGQMYDADTQCKWQFGAKAKLCGLGLVKDICKSLWCHRVGHRCETKFMPAAEGTVCGLSMWCRQGQCVKLGDLGPRPIHGQWSAWSKWSECSRTCGGGVRYQERHCNNPKPQYGGKFCPGSSRVYQLCNINPCDKNSLDFRAQQCAEYNSKPFRGWFYQWKPYMKVEEEDRCKLYCKAENFEFFFAMSSKVKDGTPCSPNKNDVCIDGICEPVGCDHELGSKAVSDACGVCKGDNSTCKFYKGLYLNQHKANEYYPVVTIPAGARSVEVQELQVSSSYLAVRSLGHKYYLTGGWSVDWPGEFAFAGTVFEYQRAFNRPECLSAPGPINETLVFEILMQGKNPGIAWKYALPKVTNGTLPASKRHSYAWSTVQTDCSVSCGGGYISVKAVCLRDQNTQVNSSFCNARARPATEPKMCNAFSCPAYWKPGEWSACSRSCAGGQQSRKVQCVQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPPEWSPGPWSQCSKTCGRGVRKREVTCRRAAVAEAVPESACAGAARPDSQEGCVLGRCPKNSRLQWLISSWSECSVSCGLGVRKREMKCSEKAFQGKLITLPERRCRNIKKPNVDLEETCSRGACPAHPVYSLAAGWYSSPWQQCTVSCGGGVQTRSVHCVQQGRPSSSCLLRQKPPVLRACNTNFCPAPAKREDPSCVDFFGWCRLVPQHGVCNHKFYGKQCCRSCSRKS", "length": 1223, "header": "tr|E1B8S3-1|E1B8S3_BOVIN Isoform 1 of A disintegrin and metalloproteinase with thrombospondin motifs 18 OS=Bos taurus OX=9913 GN=ADAMTS18 PE=4 SV=3 CANONICAL=E1B8S3-1" }, "locus": { "chromosome": "18", "start_pos": 4666475, "end_pos": 4522901, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001339.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001339.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001339.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001339.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:518395", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518395", "resource": "KEGG Pathway" }, { "id": "R-BTA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z8G4-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 18", "gene_name": "Adamts18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MECALLFLCALRAAGPGPPWGPAGLARLAKALQLCCLCCASVAVALASDSGSSGGSGLNDDYVFVVPVEVDSGGSYISHDILHNRKRRSAHGASSSVHYRFSAFGQDLHLELKPSALLSSHFIVQVLGKDGASETREPAVVQQCLYQGFIRNDSLSSVAVSTCAGLSGLIRTRDNEFLISPLPQLLAQQHNYSLPAGHHPHVLYKRTAEKRVRRYQDYPASQRTYPGHSPSHTPPASQSQETEYRHRRWQKQHFCGRRKKYAPKPPAEDAYLRFDEYGGAGRPRRSARKSQKGLNVETLVVADAKMVEKHGKDDVTTYILTVMNMVSSLFKDGTIGSDINIVVVSLILLEDEPGGLLINHHADQSLNSFCQWQSALVGKNGKRHDHAILLTGFDICSWKNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMVHDGEGNPCRKAEGNIMSPTLTGNNGVFSWSSCSRQYLKKFLSTPQAGCLVDEPKQTGQYKYPDKLPGQIYDADTQCKWQFGAKAKLCSLGVMKDICKSLWCHRVGHRCETKFMPAAEGTVCGLSMWCRQGQCVRLGDLGPRPIHGQWSAWSKWSECSRTCGGGVKYQERHCSNPKPQYGGKYCPGSSRIYKLCNINPCHENSLDFRAQQCAEYNNKPFRGWLYRWRPYTKVEEEDRCKLYCKAENFEFFFAMSGKVKDGTPCSPHRNDVCIDGICEPVGCDHELGSKAVSDACGVCKGDNSTCKFYKGLYLSQHKANEYYPVVTIPAGARSIEIQELELSSSYLAVRSLSQKYYLTGGWNIDWPGDFTFAGTTFEYQRPFNRPERLYAPGPTNETLVFEILTQGKNPGITWKYALPKVMNVTQPAAKRHHHTWRTVQSDCSVTCGGGYISIKAICLRDQNTQVNSSFCSVRTKPATEPKLCNAFSCPAYWLPGEWSTCSKSCAGGQQSRKIRCVQKKPFQKEEAVLHSLCPVSTPTQVQVCNSHACPPEWSPGPWSQCSKTCGRGVRRREVLCTSPAAETLPESLCSSSPKPEAQEGCVLGRCPKNNRLQWIASAWTECSATCGLGVRKREFKCMEKTLQGKLMTFPERRCRNIKKPNLELEETCNRRACPVYSMAAGWYSSPWQQCTVTCGGGVQTRSVHCMQQGRPSSSCLLHQKPPVLRACNTNFCPVPEKRDDPSCVDFFSWCRLVPQHGVCNHKFYGKQCCRSCSRKS", "length": 1219 }, "evidence": [ { "id": "E1B8S3", "url": "https://omabrowser.org/oma/group/E1B8S3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4VC17-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 18", "gene_name": "Adamts18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MECALLCLCALRAAGPGPPWGPAGLGRLAKALQLCCFCCASVAVALASDSGSSGGSGLNDDYVFVVPVEVDSGGSYISHDILHHRKRRSAHGASNSLHYRVSAFGQDLHLELKPSAILSSHFRVQVLGKDGASETREPEVPQCLYQGFIRNDSSSSVAVSTCAGLSGLIRTRDNEFLISPLPQLLAQEHNYSSPAGHHPHVLYKRTAEKRVRWYQDYPGSQRTYPGHSPSHTPPASQSQEPEYSHRRWQKRHFCGRRKKYAPKPPAEDAYLRFDEYGGTGRPRRSAGKSQNGLNVETLVVADAKMVEKHGKDDVTTYILTVMNMVSSLFKDGTIGSDINIVVVSLILLEEEPEGLLINHHADQSLNSFCQWQSALVGKNGKRHDHAILLTGFDICSWKNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMVHDGEGNPCRKAEGNIMSPTLTGNNGVFSWSSCSRQYLKKFLSTPQAGCLVDEPKQTGQYKYPDKLPGQIYDADMQCKWQFGAKAKLCSLGVMKDICKSLWCHRVGHRCETKFMPAAEGTACGLSMWCRQGQCVKLGELGPRPIHGQWSAWSKWSECSRTCGGGVKFQERHCSNPKPQYGGKYCPGSSRIYKLCNINPCPENSLDFRAQQCAEYNNKPFRGWLYRWKPYTKVEEEDRCKLYCKAENFEFFFAMSGKVKDGTPCSPHRNDVCIDGICELVGCDHELGSKAVSDACGVCKGDNSTCKFYKGLYLSQHKANEYYPVVTIPAGARSIEIQELQLSSSYLAVRSLSQKYYLTGGWSIDWPGDFTFAGTTFEYQRSFNRPERLYAPGPTNETLVFEILTQGKNPGIAWKYALPKVMNVTQPATKRYHHTWRTVQSDCSVTCGGGYISIKAICLRDQHTQVNSSFCSVRTKPATEPKICNAFSCPAYWLPGEWSACSKSCAGGQQSRKIRCVQKKPFQKEEAVLHSLCPVSTPTQVQVCNSHACPPEWSPSPWSQCSKTCGRGVRRREVLCKSPAAETLPESLCSSSPRPEAQEGCVLGRCPKNNRLQWIASAWSECSATCGLGVRKRELKCVEKTLQGKLITFPERRCRNIKKPSLELEEACNQRTCPVYSMAVASWYSSPWQQCTVTCGGGVQTRSVHCMQQGRPSSSCLLHQKPPVLRACNTNFCPAPEKKDDPSCVDFFSWCHLVPQHGVCNHKFYGKQCCRSCTRKS", "length": 1219 }, "evidence": [ { "id": "E1B8S3", "url": "https://omabrowser.org/oma/group/E1B8S3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "E1B8S3", "url": "https://www.uniprot.org/uniprotkb/E1B8S3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1B8S3", "url": "https://www.uniprot.org/uniprotkb/E1B8S3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1B8S3", "url": "https://www.uniprot.org/uniprotkb/E1B8S3" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "E1B8S3", "url": "https://www.uniprot.org/uniprotkb/E1B8S3" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "E1B8S3", "url": "https://www.uniprot.org/uniprotkb/E1B8S3" } ], "pmid": "" }, { "name": "negative regulation of platelet aggregation", "id": "GO:0090331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090331", "evidence": [ { "database": "UniProtKB", "id": "E1B8S3", "url": "https://www.uniprot.org/uniprotkb/E1B8S3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "E1B8S3", "url": "https://www.uniprot.org/uniprotkb/E1B8S3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 839, "end_pos": 841, "annotation": "n_glycosylation_sequon" }, { "start_pos": 866, "end_pos": 868, "annotation": "n_glycosylation_sequon" }, { "start_pos": 910, "end_pos": 912, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B8S3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1223, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B8S3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B8S3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B8S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8S3" }, { "id": "PS50900", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50900" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLAC", "eco_id": "ECO_0000259", "start_pos": 1186, "end_pos": 1223, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1B8S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8S3" }, { "id": "PS50215", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50215" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M12B", "eco_id": "ECO_0000259", "start_pos": 294, "end_pos": 499, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } 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"https://www.genome.jp/dbget-bin/www_bget?bta:507000", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LMGIWWM", "url": "https://omabrowser.org/oma/group/LMGIWWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B8V0", "url": "https://www.orthodb.org/?gene=E1B8V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MY69", "url": "https://www.orthodb.org/?gene=G3MY69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10283", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10283", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10283:SF109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10283:SF109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00939", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00939", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9955298", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9955298", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024835571", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024835571", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8V0-1", "url": "https://www.uniprot.org/uniprotkb/E1B8V0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY69", "url": "https://www.uniprot.org/uniprotkb/G3MY69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY69-1", "url": "https://www.uniprot.org/uniprotkb/G3MY69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVYWCTEVIPLAVTALLPALLFPLFKILDFKQVSIQYMKDTNMLFLGGLIVAVAVEHWKLHKRIALRTLLWVGTKPAQLMLGFMCATAFLSMWISNTATTAMMVPIVEAVLQQMEATSAATEASLGTLELAEKGKAGELPGNQTTLEGPSMRQQEVNRKNVCKAMTLCICYSASIGGTATLTGTGPNVVLLGQMQELFPDSKDIVNFASWFGFAFPNMLIMLLLSWLWLRFMYMRFDLSWGCSLEKKSEEKSAHEVLWAEYRKLGPLSFAEINVLLCFFLLVGLWFTRDPGFMPGWVSIAWTEGKTKYASDATVAIFVAILLFIMPSQKPKFNFCSQTEEERKTPFYPPPLLNWKVAQEKVPWGIVLLLGGGFAVANGCEASGLSEWMGKQMEPLHTVSPTAITLIMSSLIAVLTECTSNVATTTLFLPIFASMSRSIGLNPLYIMIPCTLSSSFAFMLPVATPPNAIVFSYGHLKVSDMMKTGLIMNVIGITCVFLAINTWGRVIFDLDQFPDWANVTTH", "length": 522, "header": "tr|E1B8V0-1|E1B8V0_BOVIN Isoform 1 of Solute carrier family 13 member 5 OS=Bos taurus OX=9913 GN=SLC13A5 PE=3 SV=4 CANONICAL=E1B8V0-1" }, "isoforms": [ { "isoform_ac": "E1B8V0-1", "url": "https://www.uniprot.org/uniprotkb/E1B8V0/entry#E1B8V0-1", "sequence": { "sequence": "MAVYWCTEVIPLAVTALLPALLFPLFKILDFKQVSIQYMKDTNMLFLGGLIVAVAVEHWKLHKRIALRTLLWVGTKPAQLMLGFMCATAFLSMWISNTATTAMMVPIVEAVLQQMEATSAATEASLGTLELAEKGKAGELPGNQTTLEGPSMRQQEVNRKNVCKAMTLCICYSASIGGTATLTGTGPNVVLLGQMQELFPDSKDIVNFASWFGFAFPNMLIMLLLSWLWLRFMYMRFDLSWGCSLEKKSEEKSAHEVLWAEYRKLGPLSFAEINVLLCFFLLVGLWFTRDPGFMPGWVSIAWTEGKTKYASDATVAIFVAILLFIMPSQKPKFNFCSQTEEERKTPFYPPPLLNWKVAQEKVPWGIVLLLGGGFAVANGCEASGLSEWMGKQMEPLHTVSPTAITLIMSSLIAVLTECTSNVATTTLFLPIFASMSRSIGLNPLYIMIPCTLSSSFAFMLPVATPPNAIVFSYGHLKVSDMMKTGLIMNVIGITCVFLAINTWGRVIFDLDQFPDWANVTTH", "length": 522, "header": "tr|E1B8V0-1|E1B8V0_BOVIN Isoform 1 of Solute carrier family 13 member 5 OS=Bos taurus OX=9913 GN=SLC13A5 PE=3 SV=4 CANONICAL=E1B8V0-1" }, "locus": { "chromosome": "19", "start_pos": 25204794, "end_pos": 25186356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006144.8", "url": "https://www.ensembl.org/id/ENSBTAT00000006144.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006144.7", "url": "https://www.ensembl.org/id/ENSBTAP00000006144.7" } ] } }, { "isoform_ac": "G3MY69-1", "url": "https://www.uniprot.org/uniprotkb/E1B8V0/entry#G3MY69-1", "sequence": { "sequence": "MASALSYVSKFKSFVILFLTPILLLPLIILMPAKFVRCAYIIIIMAVYWCTEVIPLAVTALLPALLFPLFKILDFKQVSIQYMKDTNMLFLGGLIVAVAVEHWKLHKRIALRTLLWVGTKPAQLMLGFMCATAFLSMWISNTATTAMMVPIVEAVLQQMEATSAATEASLGTLELAEKGKAGELPGNQTTLEGPSMRQQEVNRKNVCKAMTLCICYSASIGGTATLTGTGPNVVLLGQMQELFPDSKDIVNFASWFGFAFPNMLIMLLLSWLWLRFMYMRFDLSWGCSLEKKSEEKSAHEVLWAEYRKLGPLSFAEINVLLCFFLLVGLWFTRDPGFMPGWVSIAWTEGKTKYASDATVAIFVAILLFIMPSQKPKFNFCSQTEEERKTPFYPPPLLNWKVAQEKVPWGIVLLLGGGFAVANGCEASGLSEWMGKQMEPLHTVSPTAITLIMSSLIAVLTECTSNVATTTLFLPIFASMMKTGLIMNVIGITCVFLAINTWGRVIFDLDQFPDWANVTTH", "length": 520, "header": "tr|G3MY69-1|E1B8V0_BOVIN Computationally mapped isoform of Solute carrier family 13 member 5 OS=Bos taurus OX=9913 GN=SLC13A5 PE=3 SV=1 CANONICAL=E1B8V0-1" }, "locus": { "chromosome": "19", "start_pos": 25204794, "end_pos": 25181455, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066121.4", "url": "https://www.ensembl.org/id/ENSBTAT00000066121.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054497.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054497.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507000", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507000", "resource": "KEGG Pathway" }, { "id": "R-BTA-9955298", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9955298", "resource": "Reactome", "description": "SLC-mediated transport of organic anions" } ], "orthologs": [ { "uniprot_canonical_ac": "Q67BT3-1", "protein_name": "Na(+)/citrate cotransporter", "gene_name": "Slc13a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSAKTCVTKFKSFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANTAVEASLGTLELLDKNKTSELPGSQVVFEDPNVQEQEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSKDVLNYASWFGFAFPNMVMMLVLAWLWLQCLYMRHNLKKTCICCGEKKRDTEKIAYKVLNEEYQKLGSLSYPECNVLFCFTLLVILWFSRDPGFMPGWLSFAWVEGNTVHITDATVAIFVAILLFIIPSQKPKFNFSSQTEEERKTPFYPPALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPLRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLAFMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTWGRAMFNLDNFPDWANSTSVNT", "length": 572 }, "evidence": [ { "id": "E1B8V0", "url": "https://omabrowser.org/oma/group/E1B8V0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86YT5-1", "protein_name": "Na(+)/citrate cotransporter", "gene_name": "SLC13A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASALSYVSKFKSFVILFVTPLLLLPLVILMPAKFVRCAYVIILMAIYWCTEVIPLAVTSLMPVLLFPLFQILDSRQVCVQYMKDTNMLFLGGLIVAVAVERWNLHKRIALRTLLWVGAKPARLMLGFMGVTALLSMWISNTATTAMMVPIVEAILQQMEATSAATEAGLELVDKGKAKELPGSQVIFEGPTLGQQEDQERKRLCKAMTLCICYAASIGGTATLTGTGPNVVLLGQMNELFPDSKDLVNFASWFAFAFPNMLVMLLFAWLWLQFVYMRFNFKKSWGCGLESKKNEKAALKVLQEEYRKLGPLSFAEINVLICFFLLVILWFSRDPGFMPGWLTVAWVEGETKYVSDATVAIFVATLLFIVPSQKPKFNFRSQTEEERKTPFYPPPLLDWKVTQEKVPWGIVLLLGGGFALAKGSEASGLSVWMGKQMEPLHAVPPAAITLILSLLVAVFTECTSNVATTTLFLPIFASMSRSIGLNPLYIMLPCTLSASFAFMLPVATPPNAIVFTYGHLKVADMVKTGVIMNIIGVFCVFLAVNTWGRAIFDLDHFPDWANVTHIET", "length": 568 }, "evidence": [ { "id": "E1B8V0", "url": "https://omabrowser.org/oma/group/E1B8V0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CJ44-1", "protein_name": "Na(+)/citrate cotransporter", "gene_name": "Slc13a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASAKTYVTKFKSFVILFFAPILLLPLIILVPDKFARCAYVIILMAIYWCTDVIPVAITSLLPVLLFPLLKVLDSKQVCVQYMTDTNMLFLGSLIVATAVERWELHKRIALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTATTAMMIPIVEAMLEQMVATNVAVDASQRTMELLDKNKASELPGSQVVFEDPSVQKQEDEETKNMYKAMNLCVCYAASIGGTATLTGTGPNVVLLGQMQELFPDSKDVMNFASWFAFALPNMLLMLVMAWLWLLCFYMRPNLKKTCICCGRKKKDTEKIASKVLYEEYRKLGPLSYAECNVLFCFGLLIILWFSRDPGFMPGWLSIAWIEGNTKHVTDATVAIFVAILLFIVPSQKPKFNFSRQTEEERKTPFYPPPLLNWKVTQEKVPWGIVLLLGGGFAMAKGCETSGLSEWMARQMEPLSSVRPAIITLILSCIVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTLSASLAFMLPVATPPNAIVFAYGHLKVIDMVKTGLVMNILGIASVFLSVNTWGRAVFNLDKFPDWANLTHINT", "length": 572 }, "evidence": [ { "id": "E1B8V0", "url": "https://omabrowser.org/oma/group/E1B8V0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8LG88-1", "protein_name": "Tonoplast dicarboxylate transporter", "gene_name": "TDT", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNGGDVTVAGSDDLKSPLLPVVHNDEPFERQTVGQQLRTIFTPKNCYIALGPLLCAVVCLCVDLGGDETTTARNMLGVLVWMFAWWLTEAVPMPITSMTPLFLFPLFGISAADDVANSYMDDVISLVLGSFILALAVEHYNIHRRLALNITLVFCVEPLNAPLLLLGICATTAFVSMWMHNVAAAVMMMPVATGILQRLPSSSSTTEVVHPAVGKFSRAVVLGVIYSAAVGGMSTLTGTGVNLILVGMWKSYFPEADPISFSQWFFFGFPLALCIFVVLWCVLCVMYCPKGAGQALSPYLHKSHLRRELDLLGPMNFAEKMVLAVFGGLVVLWMTRNITDDIPGWGRIFAGRAGDGTVSVMMATLLFIIPSNIKKGEKLMDWNKCKKLPWNIVLLLGAGFAIADGVRTSGLAEVLSKGLVFLETAPYWAIAPTVCLIAATITEFTSNNATTTLLVPLLIEIAKNMGIHPLLLMVPGAIGAQFAFLLPTGTPSNVVGFTTGHIEIKDMIKTGLPLKIAGTIFLSILMPTLGAYVFASMGGV", "length": 540 }, "evidence": [ { "id": "E1B8V0", "url": "https://omabrowser.org/oma/group/E1B8V0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" }, { "name": "citrate transport", "id": "GO:0015746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015746", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" }, { "name": "cellular response to lithium ion", "id": "GO:0071285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071285", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" }, { "name": "alpha-ketoglutarate transport", "id": "GO:0015742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015742", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" }, { "name": "oxaloacetate transport", "id": "GO:0015729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015729", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" }, { "name": "succinate transport", "id": "GO:0015744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015744", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" }, { "name": "fumarate transport", "id": "GO:0015741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015741", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "citrate transmembrane transporter activity", "id": "GO:0015137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015137", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" }, { "name": "sodium:dicarboxylate symporter activity", "id": "GO:0017153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017153", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" }, { "name": "succinate transmembrane transporter activity", "id": "GO:0015141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015141", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" }, { "name": "solute:sodium symporter activity", "id": "GO:0015370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015370", "evidence": [ { "database": "UniProtKB", "id": "E1B8V0", "url": "https://www.uniprot.org/uniprotkb/E1B8V0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B8V0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 522, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B8V0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B8V0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 }, { "start_pos": 518, "end_pos": 520 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HCY0-1", "protein_name": "Melanocortin receptor 3", "gene_name": "Mc3r", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNSSCCLFSASPMLPNLSEHPAAPSASNRSGGGFCEQVFIKPEVFLALGIVSLMENILVILAVVRNGNLHSPMYFFLCSLAAADMLVSLSNSLETIMIAIINSDSLTLEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALALIVAIWVCCGICGVMFIIYSESKMVIVCLVTMFFAMVLLMGTLYIHMFLFARLHVQRIAALPPAHGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFKEILCGCNGVNLG", "length": 323 }, "evidence": [ { "id": "E1B8V8", "url": "https://omabrowser.org/oma/group/E1B8V8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0YY12-1", "protein_name": "Melanocortin 3 receptor", "gene_name": "MC3R", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"length": 319 }, "evidence": [ { "id": "E1B8V8", "url": "https://omabrowser.org/oma/group/E1B8V8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QQG9-1", "protein_name": "Melanocortin receptor 3", "gene_name": "mc3r", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDSHLQFLKGQKSVNSTSLPPNGSLADSPAGTLCEQVQIQAEVFLTLGIVSLLENILVISAVVKNKNLHSPMYFFLCSLAAADMLVSVSNSLETIVIAVLNSRLVVASDQFVRLMDNVCDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIVTVRRALVAIAVIWLVCVVCGIVFIVYSESKTVIVCLITMFFAMLVLMATLYVHMFLLARLHVQRIAALPPAAPGAGNPAPRQRSCMKGAVTISILLGVFVCCWAPFFLHLILLVSCPHHPLCLCYMSHFTTYLVLIMCNSVIDPLIYACRSLEMRKTFKEILCCFGCQPAL", "length": 327 }, "evidence": [ { "id": "E1B8V8", "url": "https://omabrowser.org/oma/group/E1B8V8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P32244-1", "protein_name": "Melanocortin receptor 3", "gene_name": "Mc3r", "tax_id": 10116, "organism": "Rattus 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"MHTCCPPVTLEQDLHRKMQSWMLQTLAFALTSLVLSCAETIDYYGEICDNACPCEEKDGILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLSRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLESLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVELQLEENPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGRDLDEVSKQELCPRKLISDYEMRPQTPLSTTGYLHTTPASVNSVATSSSAVYKPPLKPPKGTRQPNKPRVRPTSRQPSKDLGYGNYGPSIAYQTKSPVPLECPTACTCNLQISDLGLNVNCQERKIESIAELQPKPYNPKKMYLTENYIALVRRSDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQPGTFDPVPNLQLLFLNNNLLQTLPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLTSLIQIDLHDNPWDCTCDVVGMKLWVEQLKAGVLVDEVICKAPKKFAETDMRSIKSELLCPDYSDVVVSTPAPSSIQVPARTSAVTPAVRLNATGAPAGLGAGGGAASSVPLSVLILSLLLVFIMSVFVAAGLFVLVVKRRKKHQSDHASTHNSDVSSFNMQYSVYGGGGGGGGGSGGAGVHPHAHAQHRAPALPKVKTPAGHVYEYIPHPLGHMCKNPIYRSREGNSVEDYKDLHELKVTYSSSNHHLQPPPPPPQPQPPPPVQLQPAGEDERRESHHLRSPAYSVSTIEPREDLLSPVQDADRFYRGILEPDKHCATTPAGNSLPEYPKFPCSPAAYTFSPNYDLRRPHQYLHPGAGDSRLREPVLYSPPSAVFVEPNRNEYLELKAKLNVEPDYLEVLEKQTTFSQF", "length": 962, "header": "tr|E1B8X9-1|E1B8X9_BOVIN Isoform 1 of SLIT and NTRK like family member 5 OS=Bos taurus OX=9913 GN=SLITRK5 PE=3 SV=3 CANONICAL=E1B8X9-1" }, "isoforms": [ { "isoform_ac": "E1B8X9-1", "url": "https://www.uniprot.org/uniprotkb/E1B8X9/entry#E1B8X9-1", "sequence": { "sequence": "MHTCCPPVTLEQDLHRKMQSWMLQTLAFALTSLVLSCAETIDYYGEICDNACPCEEKDGILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLSRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLESLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVELQLEENPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGRDLDEVSKQELCPRKLISDYEMRPQTPLSTTGYLHTTPASVNSVATSSSAVYKPPLKPPKGTRQPNKPRVRPTSRQPSKDLGYGNYGPSIAYQTKSPVPLECPTACTCNLQISDLGLNVNCQERKIESIAELQPKPYNPKKMYLTENYIALVRRSDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQPGTFDPVPNLQLLFLNNNLLQTLPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLTSLIQIDLHDNPWDCTCDVVGMKLWVEQLKAGVLVDEVICKAPKKFAETDMRSIKSELLCPDYSDVVVSTPAPSSIQVPARTSAVTPAVRLNATGAPAGLGAGGGAASSVPLSVLILSLLLVFIMSVFVAAGLFVLVVKRRKKHQSDHASTHNSDVSSFNMQYSVYGGGGGGGGGSGGAGVHPHAHAQHRAPALPKVKTPAGHVYEYIPHPLGHMCKNPIYRSREGNSVEDYKDLHELKVTYSSSNHHLQPPPPPPQPQPPPPVQLQPAGEDERRESHHLRSPAYSVSTIEPREDLLSPVQDADRFYRGILEPDKHCATTPAGNSLPEYPKFPCSPAAYTFSPNYDLRRPHQYLHPGAGDSRLREPVLYSPPSAVFVEPNRNEYLELKAKLNVEPDYLEVLEKQTTFSQF", "length": 962, "header": "tr|E1B8X9-1|E1B8X9_BOVIN Isoform 1 of SLIT and NTRK like family member 5 OS=Bos taurus OX=9913 GN=SLITRK5 PE=3 SV=3 CANONICAL=E1B8X9-1" }, "locus": { "chromosome": "12", "start_pos": 62298805, "end_pos": 62295920, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091624.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091624.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093608.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093608.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 638, "start_aa": "Thr", "end_pos": 638, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr638", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:781586", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781586", "resource": "KEGG Pathway" }, { "id": "R-BTA-388844", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-388844", "resource": "Reactome", "description": "Receptor-type tyrosine-protein phosphatases" }, { "id": "R-BTA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-BTA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XTI3-1", "protein_name": "SLIT and NTRK like family member 5", "gene_name": "SLITRK5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MYACCSTVTLEQDLNKKMHIWMLQTIAFALTSLVLSWAESIEYYGEICDNACPCEEKDGILTVSCENRGIISLFEISPPRFPVYHLLLSGNLLNRLYPNQFVNYTGASILHLGSNDIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLESLEYLQVDYNYISIIEPNAFSKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVELQLEENPWNCSCELIALKDWLDSISYSALVGDVVCETPFRLHGRDLDEVSKQELCPRRLISDYEMRPQTPLSTTGYFHTTPASVNSVATSSSAVYKSPLKPPKGTRQPSKTRVRPTSRLPSKDLGYSNYGPSIAYQTKSPVPLECPTACTCNLQISDLGLNVNCQERKIESISELQPKPYNPKKMYLTENYIALVRRADFVDATGLDLLHLGNNRISVIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNVIREIEAGTFEPVPNLQLLFLNNNLLRSLPGNIFSGLSLYRLSLRSNHFSYLPVSGVLDQLKSLLQIDLHENPWDCTCDVVGMKLWLEQLNTGVLVDQVICESPKKFSQSDMRAVRAELLCPDYSDIVVSTPTPSPGQLPARTTPSSSTVRLNGTAAAAGGAAAGGGSGSSVPLSVLILSLLLVFIMSVFVAAGLFVLVMKRRKKGQGDHASANNSDVSSFNMQYSVYSGGHHQHHHHPHLQQHPPRGGGGGGGGAALPKVKTPAGHVYEYIPHPLGHMCKNPIYRSREGNAGEDYKDLHELKVTYSSHPLTPAGGAPPPPPPPAPGGEDAPGRSPAYSVSTIEPREELLSPMQDADRFYRGILEPDKHSSSSALGTPGSTLPDFPKLPAAYTYSPNYDLRRAHQYLHPGPGDSRLRETVLYSPPSTVYVEPNRNEYLELKAKLNAEPDYLEVLEKQTTFSQF", "length": 954 }, "evidence": [ { "id": "E1B8X9", "url": "https://omabrowser.org/oma/group/E1B8X9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "M0R9U3-1", "protein_name": "SLIT and NTRK-like family, member 5", "gene_name": "Slitrk5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHVCCPPVTLEQDLHRKMHSWMLHTLAFAVTSLVLSCAETIDYYGEICDNACPCEEKDGILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHMLQVLILNDNLLSGLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVELQLEENPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGRDLDEVSKQELCPRKLISDYEMRPQTPLSTTGYLHTTPASVNSVATSSSAVYKPPLKPPKGTRQPNKPRVRPTSRQPSKDLGYSNYGPSIAYQTKSPVPLECPTACTCNLQISDLGLNVNCQERKIESIAELQPKPYNPKKMYLTENYITVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLGNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNQLQAMPSGVFSGLTLLRLNLRSNSFTSLPVSGVLDQLTSLIQIDLHDNPWDCTCEVVGMKLWIEQLKVGVLVDEVICKAPKKFAETYMRSIKSELLCPDYSDVVVSTPTPSSIQLPSRTNAAATPAVKLNSTGTPAGLGAGTGASSVPLSVLILSLLLVFIMSVFVAAGLFVLVMKRRKKNQSDHTSTNNSDVSSFNMQYSVYGGGGGGGGGHPHAHVHHRGSALPKVKTPAGHVYEYIPHPLGHMCKNPIYRSREGNSVEDYKDLHELKVTYSSNHHLQQQQPPPPQQPQQQPPPQLQLQPGEEERRESHHLRSPAYSVSTIEPREDLLSPVQDADRFYRGILEPDKHCSTTPAGSSLPEYPKFPCSPAAYTFSPNYDLRRPHQYLHPGAGESRLREPVLYSPPGAVFVEPNRNEYLELKAKLNVEPDYLEVLEKQTTFSQF", "length": 958 }, "evidence": [ { "id": "E1B8X9", "url": "https://omabrowser.org/oma/group/E1B8X9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O94991-1", "protein_name": "SLIT and NTRK-like protein 5", "gene_name": "SLITRK5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHTCCPPVTLEQDLHRKMHSWMLQTLAFAVTSLVLSCAETIDYYGEICDNACPCEEKDGILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVELQLEENPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGRDLDEVSKQELCPRRLISDYEMRPQTPLSTTGYLHTTPASVNSVATSSSAVYKPPLKPPKGTRQPNKPRVRPTSRQPSKDLGYSNYGPSIAYQTKSPVPLECPTACSCNLQISDLGLNVNCQERKIESIAELQPKPYNPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDNPWDCTCDIVGMKLWVEQLKVGVLVDEVICKAPKKFAETDMRSIKSELLCPDYSDVVVSTPTPSSIQVPARTSAVTPAVRLNSTGAPASLGAGGGASSVPLSVLILSLLLVFIMSVFVAAGLFVLVMKRRKKNQSDHTSTNNSDVSSFNMQYSVYGGGGGTGGHPHAHVHHRGPALPKVKTPAGHVYEYIPHPLGHMCKNPIYRSREGNSVEDYKDLHELKVTYSSNHHLQQQQQPPPPPQQPQQQPPPQLQLQPGEEERRESHHLRSPAYSVSTIEPREDLLSPVQDADRFYRGILEPDKHCSTTPAGNSLPEYPKFPCSPAAYTFSPNYDLRRPHQYLHPGAGDSRLREPVLYSPPSAVFVEPNRNEYLELKAKLNVEPDYLEVLEKQTTFSQF", "length": 958 }, "evidence": [ { "id": "E1B8X9", "url": "https://omabrowser.org/oma/group/E1B8X9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q810B7-1", "protein_name": "SLIT and NTRK-like protein 5", "gene_name": "Slitrk5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHVCCPPVTLEQDLHRKMHSWMLQTLAFAVTSLVLSCAETIDYYGEICDNACPCEEKDGILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLSRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHMLQVLILNDNLLSGLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVELQLEENPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGRDLDEVSKQELCPRKLISDYEMRPQTPLSTTGYLHTTPASVNSVATSSSAVYKPPLKPPKGTRQPNKPRVRPTSRQPSKDLGYSNYGPSIAYQTKSPVPLECPTACTCNLQISDLGLNVNCQERKIESIAELQPKPYNPKKMYLTENYITVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLGNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQAGTFDPVPNLQLLFLNNNQLQAMPSGVFSGLTLLRLNLRGNSFTSLPVSGVLDQLTSLIQIDLHDNPWDCTCDVVGMKLWIEQLKVGVLVDEVICKAPKKFAETYMRSIKSELLCPDYSDVVVSTPTPSSIQVPSRTNAATPAVRLNSTGTPAGLGAGTGASSVPLSVLILSLLLVFIMSVFVAAGLFVLVMKRRKKNQSDHTSTNNSDVSSFNMQYSVYGGGGGGGGGHPHAHVHHRGPALPKVKTPAGHVYEYIPHPLGHMCKNPIYRSREGNSVEDYKDLHELKVTYSSNHHLQQQPPPPPQQPQQQPPPQMQMQPGEEERRESHHLRSPAYSVSTIEPREDLLSPVQDADRFYRGILEPDKHCSTTPAGSSLPEYPKFPCSPAAYTFSPNYDLRRPHQYLHPGAGESRLREPVLYSPPGAVFVEPNRNEYLELKAKLNVEPDYLEVLEKQTTFSQF", "length": 957 }, "evidence": [ { "id": "E1B8X9", "url": "https://omabrowser.org/oma/group/E1B8X9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "E1B8X9", "url": "https://www.uniprot.org/uniprotkb/E1B8X9" } ], "pmid": "" }, { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "E1B8X9", "url": "https://www.uniprot.org/uniprotkb/E1B8X9" } ], "pmid": "" }, { "name": "synaptic membrane adhesion", "id": "GO:0099560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099560", "evidence": [ { "database": "UniProtKB", "id": "E1B8X9", "url": "https://www.uniprot.org/uniprotkb/E1B8X9" } ], "pmid": "" }, { "name": "regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission", "id": "GO:0150035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150035", "evidence": [ { "database": "UniProtKB", "id": "E1B8X9", "url": "https://www.uniprot.org/uniprotkb/E1B8X9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "E1B8X9", "url": "https://www.uniprot.org/uniprotkb/E1B8X9" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "E1B8X9", "url": "https://www.uniprot.org/uniprotkb/E1B8X9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8X9" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 235, "end_pos": 285, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 638 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 644, "end_pos": 646 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1B8Y4-1", "uniprot_ac": "E1B8Y4", "uniprot_id": "E1B8Y4_BOVIN", "mass": { "chemical_mass": 312943.0, "monoisotopic_mass": 312943.0 }, "refseq": { "ac": "NP_001291257", "name": "otogelin precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291257" }, "gene_names": [ { "name": "OTOG", "type": "recommended", "evidence": [ { "id": "E1B8Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4" } ] }, { "name": "OTOG", "type": "synonym", "evidence": [ { "id": "NP_001291257", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291257" } ] } ], "protein_names": [ { "name": "Otogelin", "type": "recommended", "evidence": [ { "id": "E1B8Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4/entry#names_and_taxonomy" } ] }, { "name": "otogelin precursor", "type": "synonym", "evidence": [ { "id": "NP_001291257", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291257" } ] } ], "function": [ { "annotation": "Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes.", "evidence": [ { "database": "UniProtKB", "id": "E1B8Y4", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4#function" }, { "database": "UniProtKB", "id": "ARBA00057928", "url": "https://www.uniprot.org/uniprotkb/ARBA00057928#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B8Y4", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OTOG", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4", "locus": { "chromosome": "15", "start_pos": 34871462, "end_pos": 34959413, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000987", "url": "https://www.ensembl.org/id/ENSBTAG00000000987" } ] } } ], "crossref": [ { "id": "ENSBTAG00000000987", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000987", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506301", "url": "https://www.ncbi.nlm.nih.gov/gene/506301", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:506301", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506301", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YREPPGK", "url": "https://omabrowser.org/oma/group/YREPPGK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B8Y4", "url": "https://www.orthodb.org/?gene=E1B8Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339:SF228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339:SF228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25960", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25960", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25961", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25961", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001291257", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291257", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1B8Y4", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8Y4-1", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAPAPVFCLLLACVWLPRGEPAGEFPPLQSLAAAATPRGNAELQPEPARDPSHSHQEAVLAIGDATTVMGGQEEAEVLDSLAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGLRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGHHEPEGQIFSVQVHNDPQCGSFPYTCSRSVSLFFAGEQEIHLAKEVTRGGVRLQLPHVMGNLRLQLLAGYVLVRLQSAFTLAWDGTSAVYIKMSPEFLGWTHGLCGNNNADPQDDLVTSYGKLTDDVAEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQTPGTMQGVYDRCEALLRPPFDTCHAYVSPLPFMASCTSDLCQSAGDEATWCRALAEYARACAQAGRPLQGWRNQLQSCTVLCKEKAFVYNECVACCPASCQPRASCVDSEIACVDGCYCPDGLIFEDGGCVAPAECPCEFHGTLYPTGSVVKEDCNSCTCTAGRWVCSTSVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVMLQNAPCGLNQDGVCVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKVTPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSRLDPCDVHLQAASFALQACSVLTGELFAPCSAYLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCQRHGLPVDFRARLPGCALSCEATKEYSPCVAPCGQTCQDLAGPEACGVDGGSDLRGDECVEGCACPPDTYLDTQADLCVPRNHCSCHFQGMDYPPGDSDVPTLGHCHCKDGVMSCDSGAPAAACPAGQVFVNCSDLHADPELSRERTCEQQLLNLSVPARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYYPGDQVMSPCHSCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDFSFSVIVENVNCYSSGIICRKFISINVGNSLIIFDDDSGNPSPESFLDEKQQVHTWRAGFFTLVHFPREHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTVNEMRTPENLELTNPQEFGGSWAAVECPDTLDPRDTCVLNPLREPFAKKECSVLLSKVFETCHPVVDVSWFYSNCLTDTCGCSRGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKALGKGPYQLASLAAGGALVAMKVAGGALVLVRAEDVAPGDIVNFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQADDAFRHHASFSLHRGTWRAGLVALESLAEPGAFLYVSGPVLALRPYEHTEAFRWGTLFRLLDAKPSGAAYPTCEWHYDACASPCFQTCRDPWAAGCRDVPRVEGCVPACATPKVLDEVTQRCVHLEDCVEPVDLVPREALGNETLPPGQALPTASDREPQFPQEAPGASSHRPALTPTAPLTTALNPPTAATVGPALSPGPAQATQQQLLGVTASNLPEHPTEAPASKGVTAGHPASSGAPEPSSLPVSQHVPTSGMGSGAMETTRVTVILAESPNITVSSLSPPAPRFPLMTKAVTVLGLGSLPVKTTPLQPFPSLELPASPSPAVTSRPPTSSGAREASLTPAMTKVMTETGVPQSIQAQGPSSPSSPPAEARTAAEKIPAHTLVTESVETVPSPEKVQPGPDQPTGLPAAPLPSPLPMASARPAQHATTAARPPAQPSGTAAAASLSTVAHSLGATPFTTLESTRPAQLLSGLPPDTSLPLAKVGTSAPVATPGPKGSTLTPPLQQQATSLAVATTLPAGTLSPAPPLTLAVVAQGHQPGHAVPQATGTAPGLLLGATLPTPGVVAVAEGVASTVSAAPRKSTTEKTVILSKQVSLPTWISGSAQGRPTELMPAVAHTAATLVMGAEGPWAGTVPLVPTSYPLSQVSARTASRESPLILPPQLAEAHGTSAGPQPPAEPEGEATTQQSGRSAPAVQSVSAGSAEALAITAEAKTPAACVPIAEQDCVRHICLQGELIRVNQSQHCPQGAAPPRCGVLGLAVRVGGDRCCPIWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQRPEEMVTVHVLDCKSANLGHLNWPPFCLVMLTVTHKTHEVTIDRFNRKVSVDSQPAWPPVSWHGFRIEDTGHMYVIRTPSHIQIQWLHSSGLMILEASRASEAQGRGLCGICDGDVANDLTLKDGSVVSEAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATADCSPCLRMVSNRTFSACHRFVPPESFCDLWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDHCPFLCSSDSTYQACVSACEPAKTCQDGMLGPLDPEQCQVLGEGCVCSEGTILHRRHSGLCIPEEKCACTDSTGMPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPGPRPESCPRFGEVALLQPTEDPCCLGTVCVCNQTLCEGLAPTCSPGHRLLTHFQEDSCCPSYSCECDPDLCEAVQVPSCRQDQILITGRLGDSCCISYLCACGDCPDPIPECQEGEALTVDRNTTELCCPLYQCVCESFRCAHVQCGMGTALVEVWSPERCCPYKSCECDCDTIPVPRCHLWEKSQLDEAFMRSAENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTDVLDPLTSFYQINTTSVLCDVHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCTRHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSNTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTLQEPTDCACQWS", "length": 2920, "header": "tr|E1B8Y4-1|E1B8Y4_BOVIN Isoform 1 of Otogelin OS=Bos taurus OX=9913 GN=OTOG PE=3 SV=2 CANONICAL=E1B8Y4-1" }, "isoforms": [ { "isoform_ac": "E1B8Y4-1", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4/entry#E1B8Y4-1", "sequence": { "sequence": "MGAPAPVFCLLLACVWLPRGEPAGEFPPLQSLAAAATPRGNAELQPEPARDPSHSHQEAVLAIGDATTVMGGQEEAEVLDSLAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGLRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGHHEPEGQIFSVQVHNDPQCGSFPYTCSRSVSLFFAGEQEIHLAKEVTRGGVRLQLPHVMGNLRLQLLAGYVLVRLQSAFTLAWDGTSAVYIKMSPEFLGWTHGLCGNNNADPQDDLVTSYGKLTDDVAEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQTPGTMQGVYDRCEALLRPPFDTCHAYVSPLPFMASCTSDLCQSAGDEATWCRALAEYARACAQAGRPLQGWRNQLQSCTVLCKEKAFVYNECVACCPASCQPRASCVDSEIACVDGCYCPDGLIFEDGGCVAPAECPCEFHGTLYPTGSVVKEDCNSCTCTAGRWVCSTSVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVMLQNAPCGLNQDGVCVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKVTPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSRLDPCDVHLQAASFALQACSVLTGELFAPCSAYLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCQRHGLPVDFRARLPGCALSCEATKEYSPCVAPCGQTCQDLAGPEACGVDGGSDLRGDECVEGCACPPDTYLDTQADLCVPRNHCSCHFQGMDYPPGDSDVPTLGHCHCKDGVMSCDSGAPAAACPAGQVFVNCSDLHADPELSRERTCEQQLLNLSVPARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYYPGDQVMSPCHSCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDFSFSVIVENVNCYSSGIICRKFISINVGNSLIIFDDDSGNPSPESFLDEKQQVHTWRAGFFTLVHFPREHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTVNEMRTPENLELTNPQEFGGSWAAVECPDTLDPRDTCVLNPLREPFAKKECSVLLSKVFETCHPVVDVSWFYSNCLTDTCGCSRGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKALGKGPYQLASLAAGGALVAMKVAGGALVLVRAEDVAPGDIVNFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQADDAFRHHASFSLHRGTWRAGLVALESLAEPGAFLYVSGPVLALRPYEHTEAFRWGTLFRLLDAKPSGAAYPTCEWHYDACASPCFQTCRDPWAAGCRDVPRVEGCVPACATPKVLDEVTQRCVHLEDCVEPVDLVPREALGNETLPPGQALPTASDREPQFPQEAPGASSHRPALTPTAPLTTALNPPTAATVGPALSPGPAQATQQQLLGVTASNLPEHPTEAPASKGVTAGHPASSGAPEPSSLPVSQHVPTSGMGSGAMETTRVTVILAESPNITVSSLSPPAPRFPLMTKAVTVLGLGSLPVKTTPLQPFPSLELPASPSPAVTSRPPTSSGAREASLTPAMTKVMTETGVPQSIQAQGPSSPSSPPAEARTAAEKIPAHTLVTESVETVPSPEKVQPGPDQPTGLPAAPLPSPLPMASARPAQHATTAARPPAQPSGTAAAASLSTVAHSLGATPFTTLESTRPAQLLSGLPPDTSLPLAKVGTSAPVATPGPKGSTLTPPLQQQATSLAVATTLPAGTLSPAPPLTLAVVAQGHQPGHAVPQATGTAPGLLLGATLPTPGVVAVAEGVASTVSAAPRKSTTEKTVILSKQVSLPTWISGSAQGRPTELMPAVAHTAATLVMGAEGPWAGTVPLVPTSYPLSQVSARTASRESPLILPPQLAEAHGTSAGPQPPAEPEGEATTQQSGRSAPAVQSVSAGSAEALAITAEAKTPAACVPIAEQDCVRHICLQGELIRVNQSQHCPQGAAPPRCGVLGLAVRVGGDRCCPIWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQRPEEMVTVHVLDCKSANLGHLNWPPFCLVMLTVTHKTHEVTIDRFNRKVSVDSQPAWPPVSWHGFRIEDTGHMYVIRTPSHIQIQWLHSSGLMILEASRASEAQGRGLCGICDGDVANDLTLKDGSVVSEAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATADCSPCLRMVSNRTFSACHRFVPPESFCDLWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDHCPFLCSSDSTYQACVSACEPAKTCQDGMLGPLDPEQCQVLGEGCVCSEGTILHRRHSGLCIPEEKCACTDSTGMPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPGPRPESCPRFGEVALLQPTEDPCCLGTVCVCNQTLCEGLAPTCSPGHRLLTHFQEDSCCPSYSCECDPDLCEAVQVPSCRQDQILITGRLGDSCCISYLCACGDCPDPIPECQEGEALTVDRNTTELCCPLYQCVCESFRCAHVQCGMGTALVEVWSPERCCPYKSCECDCDTIPVPRCHLWEKSQLDEAFMRSAENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTDVLDPLTSFYQINTTSVLCDVHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCTRHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSNTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTLQEPTDCACQWS", "length": 2920, "header": "tr|E1B8Y4-1|E1B8Y4_BOVIN Isoform 1 of Otogelin OS=Bos taurus OX=9913 GN=OTOG PE=3 SV=2 CANONICAL=E1B8Y4-1" }, "locus": { "chromosome": "15", "start_pos": 34959346, "end_pos": 34872516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001310.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001310.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001310.6", "url": "https://www.ensembl.org/id/ENSBTAP00000001310.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1821, "start_aa": "Thr", "end_pos": 1821, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1821", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1890, "start_aa": "Thr", "end_pos": 1890, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1890", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 316, "start_aa": "Thr", "end_pos": 316, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr316", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:506301", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506301", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZZC7-1", "protein_name": "Otogelin", "gene_name": "OTOG", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGVRLLLGALLCAGLPPAWPPRGAGAQHPAGGDLSLLSTSSSAGPWREDGLGAAVQESGMTVHNASATTVLLSQSRRLHSMKCGPSSSFMCFNGGECVYKELCNCSRFNASGPRCQTVYNTGAERDHICRTWGQYHFETFDGLYFYFSGKSTYALVRHTELDEQSFSIQVNNDPECHSSPYSCKRSVSLFFSGDEQIKMSSEVTYKGFGLQLPSVIGNLHIQKLAGYFLVRHQYAFTLAWDGVSAVYIKMAPQYLGKTHGLCGNNNAVLQDDLETSYGKLTDDITEFVESWQENPPQGQPTWDNSFLSEPPCLTQSHESLQRTYTLCNILLHPPFEQCHEYVSPLPFMASCTSDLCMSAVDNATWCRALTEYARACAQAGKPLHGWRRHFQPCVITCLEPLTYNECINCCPVSCHQQSQCIDSELPCIDGCYCPDGLIYENELCVKPMDCPCDYHGSSFEIGSVVYEECNNCTCIGGKWICTNLTCPAECSVSGDIHFMTFDGREYTFQATCQYILAKSRTSGEFTVSLQNAPCGQNQDGSCIQSISIILKQDPKRQVTLTHSGDVLIYDQYKINLPYADDLFEIRKLSSVFLQVKTRIGLQMLYDREGLRLYLQADGRWKDNTIGLCGTFNGNMEDDFLSPVGVTESTPQLFGNAWKTSSACILVHDSSQMDPCDIHLQSASYAAEACSILTKDLFAPCYPYLSPIPYFEQCRRDTCKCGQNCFCSALAHYAHHCKRFGIVIDFRRSVPDCALSCEDTKEYSTCVSTCGRTCQALSVPETCSSDCVEGCACPFGTYLNSKTERCVERNECPCYFQGIDYPPGDNVITSLGKCHCSNGVMNCDTIIAHSCPVGQIYINCSNSKVDAELSRERTCENQLLNLTFSAHLPCVSGCVCPPGLVKHGDVCLETDECPCLWKGKEYFPGDKVISSCHTCICQHGSFQCTFHPCPSMCTAYGDRHYRTFDGLTYDFVGTCKAYLVKSTSSASFSVVIQNINCFNTGIICRKDIFINVGKSSLIFDDETGNPSSSSYMDKLQKIQLWKAGFFTVVHFPDEHITILWDQRTTVHVQMGHQWQGELTGLCGNFDLKTINELRTPDNFELTNSQEFGNSWTAVECVDRSDIQNPCSLNPLREPFAKKECGILFSEAFEACHPVIDVTWFYSNCLADTCGCNQGGDCECFCTSVSAYAHQCCQHGVSVDWRTPRVCPYDCEYFNKALGKGPYKLLSYINGEFVMAAKLANGFVFPVREDDITPEHIVGFMLTSGLYKPKAHDSNLVSFEAAERPNYFLQLSSSNTLVLSKWEKSEEFHNKSTFIIHKNTWLSGYSSFESFAKPGYFIHISMSSVELLKYHHSEEFRLSILLELVDVKFLSRSACEWHYDACASPCFKTCRDPLGKNCQTVPKVEGCIPACPLNMLLDEVTQRCVYFEDCIEPADGTSPLPPSTRTPAASHLTFSTTLAAVSQVVTSFPLPETKDMKTTLASKLKLPATTEKTTFSAIASNTTLPAITLSSYVSSQPREMASAERTTTMHETAKSNVSLSSLADISLFPSPVTSETSTKIQVISSGSTKLLRTTEPLIVTSPHAVSRSPELEGQPLSTFVFTGTPITFKTTELPVKTKIMEISEIATMAIPTKEAQVKLEGLAPFTPSSFESGTGKTAYQPQDSTLSPLGVRSYTSSANLTSTSEMTKTRIGQSSTAVPNVTVTSFSPVITTSSSLKPVSSEMTRTAVVLTEQSTKTILSSASTLPVSLGKAITESPIEKVHHLTDAVGIPFTTTLGSKTTTLQPQERSLKTTLLPFTIQEKETPKVTSHVEHTPSSLFLPYSLHPSSTVGKTTSLSTGRPSGSVPTPVSPDLAELKKTFKTASTTAYSSHTVLNSTEVLTTLYTKYPVLPESTRMPPLFVKVTSKITSPFELEAKSTGKTLTDYKSPLVLSTVKKSTSAYSGSIATTSTMKTFISSKETAAVPSISTKSKSAQTMSFTGSPHTLLSASETTLLLTQPDESEEERITSISTTKTSVFPSSPSSSLISLNISLPSQSIYGKEASVTALSPVHTSHAVFPVTKSSHTFSTSQHLEDQSVSSLPLAQTLPRVTTTLKYPVVETKVVSTASQSTVESITDMVKPTTATAQTSFTPSSGDKVPVQTTGAVTLPHLSATMAMELAHQTSKPSLTSKSNFSVYQHPDETLTKPTDQPRILLSTTEATVESTFSSSLTTSLPKGIHSDILSISLDTTGVILPTEKELILTDSVTQPYVPRTTALQSTVPARKTADITFETSILPSSPELFAISSSSATLEKGAFPSISTQKADTSLKSTRQAPITESFVSSHAPEITITSSVLLPETTEIPIMTESEPSIGAFLTPVISTASTSMVKTTTEKTALLPKQVTHSTAAYSSTFPATTVLSAMAHSSRVASASSTVRGTGQSITAPPATSDKIETVTKSTTTLVKPTYFSVTSESKELMFPDTEKSEELDVQPVHAQGVAITSEIPQKFYSPYFTNTTAAPSNVSVLIPFTIHSSSETKPFSSIAAASLATQTSKHGITSEVQTPSQSSLLMISDHPNDTTAPSVSSFAYLPTKPFYGLPTTIADGLATTEAMPGVTQPASMLPTETATLQTCTPITENECIKYICLDGQLIQVNKSQNCPYNATQPSCGVLGYAAQINGDKCCPKWECACRCTIFSDLSVVTYDGNHLALFKEASYIVSQTQDETITIHVLDCRMNNSNSTSLCLAMLNLTYVSNQIIIHRLSRKITVNSRFAWPTVRKYGYKVEDSGYKYAVETPTKIKIQWFHNTGVMIIEFNTTREPKALGLCGFCDGSLENDLMLPNRTVLSKNDAPSTFIDSWQVPDTLKYVGEDRHQETNCSVTDCSECLRLVLNQTFSSCHPYVPPEVFCDIWVQDSEYIQNPCVSLAAYVAMCNKFNICIEWRSNDYCPFACSENFSYQACIAACEVAESCQNNEVAALDSDTCLVLTEGCVCAEGTVLHRAHTAVCIPEEKCACTDSSGAPHAVGDIWKTSLSGCCMEKCVDIETIIPVEYNCSDTHSFDCQRFAEVVLLVPGDQTCCPQKICICNQSLCEPLIPECNDLEKLVIYYNEESCCPNYVCECDPAKCEPMEHMPSCQEDQTLIATRVESTCCISYICACGACSDQIPKCQEGEVLIVDDNTTERCCPTYQCICEIHRCPEFKCMLGMSLVEVWSPEKCCPFRTCECACEMIPKPQCKLGQKLQIDEQFQNSSENICNCVKYKCVRDKVCLSNERGVLLPGQTIVEHSLDGICHISYCTNVIDPSTKYYRINTSSVACAVECKDNQVYQPPKDLTTCCGSCKNISCLYTFNNGTVSNFKPGTTWISNCVRYECIHTAVGSVLVASSVGCPPFNETECVKVGGYVVPFLEGCCKTCKEDGKFCKKVTVRMTIRKNDCRSNTPVNIVSCDGKCPSASIYNYNINTYARFCKCCRELGLQRRTVQLYCTSNSTWVSYSIQEPTDCSCQWS", "length": 3481 }, "evidence": [ { "id": "E1B8Y4", "url": "https://omabrowser.org/oma/group/E1B8Y4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZCV6-1", "protein_name": "Otogelin", "gene_name": "Otog", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGARAPRLCLLLSCFCLLRVEPAAELEFKRTVQHQASALTWKAGEELQQEPAPEPSHSYQMPFAVEDVTTAMEGQDAEAFDAPAMSSWERRLHRAKCAPSYLFSCFNGGECVHPALCDCRRFNATGPRCQLVYNAGPERDSICRAWGQHHVETFDGLYYYFSGKGSYMLVGHHEPEGQSFSIQVHNDPQCGPAHYTCPRSVSLFLSGEREICLAKEVTHGGIRIQLPQVVAGVQLQQLAGYVIARYPSAFTLAWDGASAVYIKMSPEFVGWTHGLCGNNNADPQDDLVTSYGKLTDDIGEFVHSWQEQVPNSPPVPVMSSLPRPPCLQQSPASMQGVYERCEVLLRSPFDACHAYVSPLPFTASCTSDLCQSGGDEATWCRALTEYARACAQAGRPLQGWRTQLSQCTVRCKEKIFIYNECIACCPASCQSHASCVDSEIACVDGCYCPNGLIFEDGVCMSPAECPCEFHGTLHPPGSVVTEDCNTCTCTAGKWVCSSSVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKITPPYSDDAFEIQKLSSVFLRVRTNVGVRILYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACVPLAPGSLLDPCDVHLQAASYALQACSVLTGELFAPCSAYLSPIPYFEQCRRDACRCGQPCLCATLAHYARLCRRHGLPVDFRARLPACALSCEATKEYSPCVALCTQTCQDLASPDVCGANGGGNFSRDECVEGCTCPPDTFLDTQTDLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAATCPAGQVFVNCSELHPDPELSRERTCEQQLLNLSLPARGPCLSGCACPLGLLRHGDSCFPPEECPCTWKGKEYFPGDQVVSSCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSELSFSVMVEDVNCYSAGVICRKSISINVGSSLIIFDDDSGDPSPESFLDEKQAVHIWRAGFFTLVHFPREHITLLWDQRTTVHVQAGPQWQGQLVGLCGNFDLKTVNEMRTPENLELTNPQEFGSSWAAVECPDTPDPRDTCVLNPLREPFARKECGILLSEVFETCHPVVDVTWFYSNCLTDTCGCSRGGDCECFCASVAAYAHQCCQHGVVIDWRTPRICPYDCDFFNKALGKGPYQLSSVMAGSALVAMRAVDGDIALVRAEDLVPGDISSFLLTAALSKAKAHDPDVVSLEAADRPNFYLHVTANGSIRLAKWRRDEAFHQHASFSLHRGTWQAGLVALESLAKPGSFLQSSGLKLALRTYEHTEAFRGGALFRLLDAKPSGAAYPICEWHYDACASPCFQTCRDPQAASCQDVPRVEGCVPVCPTPKVLDEVTQRCVYLEDCVEPALRGPKETLGNETLAPGQVLPTTSDKQQLPQEPPGASTHIPVLDPLAPLTSAPNPPMAATEGPVASPGSTQPTLQTSLGLTTSNLPAGHTEATAREEGAASLLATSPPPGSSSSLPSSLQTPTSGILSSTTETTKVTLTFAGSPNTTVTSRSPPVPRFPLMTKAVTVPSHDSFPVKTTPLRPSWSLSSRPTTSPGVTSWPPTSLGSHLSTVVTNVTNKTETSLSVLAQSTKSSSQPLSTAYRAPASPLVTKGLEGASATEKGDAGHSQLTELPVSPPPSSAPIDLPHPAQHTTTAPGSPALSPGILGAGSPSTGAHGLGTTALASLETTRPPHLLSGLPPDTSLPLAKVGTSAPVATPASKGYVPTPPPQHWATTSATAMTVTPLTQTTLSLTAPLMSAVEEQAHSPSPTAPHITAMTPSFGASAGTAGVPPMVSVAPQKSTTQRAAILSKKVSPPTLISDSVQGGFTELTPTVSHTVAPLVTEAEGPQAGTVPLVPTTHSLSRVSARTASREGPLVLLPQLAEAHGTPAGLQPQEDLVRQATTEQTGRSAPAQSIAEGSMEAEGNTSAICVPIAEQDCVRHICLEGQLIRVNQTQHCPQGAVRPRCGVLGLAVRVGGDHCCPLWECACRCSIFPDLSFVTFDGSHAALFKEAIYILSQSPDEIISVHALDCKSANLGHLNWPPFCLVILNVTHLTHHISIDRFNRKVTVDSQVVWPPMSRYGFRIEDTGHMYIVQTPSHIQIQWLHSSGLMILEASKASKTQGHGLCGICDGDTANDLTLKDGSVLGEAEDPALFLDSWQVPSSLTSEGQTRFRPDSCSTADCSPCLRMVSNRTFSACHSFVSPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRGSDYCPFLCSSDSTYQACVAACEPPETCQDGVLGPLDPEQCQVLGEGCVCSEGTILHRRHSALCIPEDKCACTDSTGVPRALGETWNSSLSGCCQQQCQAPDTITPMDPDCPGPRPESCPRFGEVILLQPTEDPCCLGSVCVCNQTLCEGLAPTCRPGHRLIPHFQEDSCCPSYSCECDPGLCEAEQVPTCRQDQVLIEGRLGDSCCPSYFCGCGECPDAMPECQEGEVLTVHRNSTELCCPLYQCVCESFRCPQIQCGMGTSLVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTDVLDPLTNFYQINITSVLCDMHCEANQEYDHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCGSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNDCRSNTPVNLVSCDGRCPSASIYNHNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS", "length": 2902 }, "evidence": [ { "id": "E1B8Y4", "url": "https://omabrowser.org/oma/group/E1B8Y4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O55225-1", "protein_name": "Otogelin", "gene_name": "Otog", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGARMPRRCLLLLSCFCLLRVESTAEVQHQASALTWKISAELQQEPAPEPSHTYQEMSLAVEDVTTVMEGQEAEALAASAMSSWERRLHRAKCAPSYLFSCFNGGECVHPALCDCRRFNATGPRCQLVYNVGPERDSICRTWGQHHVETFDGLYYYFSGKGSYTLVGHHEPEGQSFSIQVHNDPQCGSAHYTCPRSVSLFLSGEREICLAKEVTHGGVRVQLPQVVGGVQLQQLAGYVIARHPSAFTLAWDGISAIYIKMSPEFLGWTHGLCGNNNADPQDDLVTSYGKVTDDVGEFVHSWQEQVPNSPPGPVTTSLPRPPCLQQSPASMQGVYERCEVLLRPPFDTCHAYVSPLPFAASCTSDLCQSGGDEATWCRALMEYARACAQAGRPLQGWRTQLSQCTVHCKEKAFIYNECIACCPASCQSRASCVDSEITCVDGCYCPNGLIFEDGGCMSPAECPCEFHGTLHPPGSVVTEDCNACTCTAGKWVCSSSVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKITPPYSDDAFEIRRLSSVFLRVRTNVGVRILYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACVPLVPGSLLDPCDVHLQAASYALQSCSVLTGELFAPCSAYLSPIPYFEQCRRDACRCGQPCLCATLAHYARLCRRHGLPVDFRAHLPACALSCEATKEYSPCVTLCAPTCQDLASPDVCGANGGGNFSREECVEGCTCPPDTFLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSELHPDPELSRERTCEQQLLNLSVPARGPCLSGCACPQGLLRHGDACFPPEECPCTWKGKEYFPGDQVVSSCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPYDFVGACKVHLVKSTSELSFSVMVEDVNCYGSGVICRKSISINVGSSLIIFDDDSGDPSPESFLDEKQAVHIWRAGFFTLVHFPREHITLLWDQRTTVHVQAGPQWQGQLVGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTPDPRDTCVLNPLREPFARKECGILLSEVFETCHPVVDVTWFYSNCLTDTCGCSRGGDCECFCASVAAYAHQCCQHGVVIDWRTPRICPYDCDFFNKALGKGPYQLSSVAAGGTLVATKAVDSDIALVRAEDLAPGDISSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHTTANGSIGLAKWQRDEAFHQHASFSLHRGTWQAGLVALESLAKPGSFLHSSGLELALRAYEHTEVFRGGALFRLLDAKPLGAAYPTCEWRYDACASPCFQTCRDPRATSCQDVPRVEGCVPVCPTPKVLDEVTQRCVYLEDCVEPAPRGPTETLGNETLVPGQVPPTTSAEQQLPQGLPGASAYSPAPVPVAPPTSAPNPPMAATEGQAPSPGSTQPTLQTPLGLTTSNFPAGHTEATAREEGAASLLTTSHPPGFSSSLPSSLQMPTSGIVSGATETTKVTITFTGSPNTTVASRSPPIPRFPLMTKAVTVPSHDSFPVKTTPLQPSWLWSLSSRPMTSLGATSWPPTSPGSHLSTAVTKVANKTMTSLSVLAQSTSSSSQPLAAVTTAHRAPASPLVTKGLEVVSATEKGEAGHSQLTELPVSPPPSPAPIDLPHPAQHTTTAPGPSALSPGILAAGSPSTGAHRPGATALASLEPTRPPHLLSGLPLDTSLPLAKVGTSAPVATPGSKGYIPTPPPQHQATTLATAMTVSPLTQSLSLTVPLMSAVEEQAHSPSPKPPQGTGMAPDQMLGATLPSFGASSVIAGVPPTVSAAPRKSTTQRAAILSKKVSPPTLISDSVQGGFTELTPIVSHTVTPLATEAEGPRAGTVPLVPTTYSLSRVSARTASREGPLVLLPQLAEAYGTPAGLQPQEDLVRQATTEQSGRSAPAKSIAEESMEAEVNTSATCVPIAEQDCVRHICLEGQLIRVNQTQHCPQGAVRPRCGVLGLAVRVGGDRCCPQWECACRCSIFPDLSFVTFDGSHAALFKEAIYVLSQSPDETISVHVLDCKSANLGHLNWPPFCLVILNVTHLAHHVSIDRFNRKVTVDSQVVWPPMSRYGFRIEDTGHMYIVRTPSHIQIQWLHSSGLMILEASKVSKTQGHGLCGICDGDAANDLTLKDGSVLGEAEDPAPFLDSWQVPSSLTSEGQTRFRPDSCATADCSPCLRMVSNRTFSACHSFVSPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRGSDYCPFLCSSDSTYQACVAACEPPDTCQDGILGPLDPEQCQVLGEGCVCTEGTILHRRHSALCIPEDKCACTDSTGVPRALGETWNSSLSGCCQQQCQAPDTIIPVDLDCPGPRPESCPRFGEVILLQPTEDPCCLGSVCVCNQTLCEGLAPTCRPGHSLITHFQEDSCCPSYSCECDPGLCEAEQVPTCREDQILIEGRLGDSCCTSYFCGCGECSDPMPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGMGTSLVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTDVLDPLTNFYQINITSVLCDMHCEANQEYDHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCGSTPLGAVLVRSPISCPPFNETECAKVGGSVVPSLEGCCRACKEDGRSCKKVTIRMTIRKNDCRSNTPVNLVSCDGRCPSASIYNHNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS", "length": 2911 }, "evidence": [ { "id": "E1B8Y4", "url": "https://omabrowser.org/oma/group/E1B8Y4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZRI0-1", "protein_name": "Otogelin", "gene_name": "OTOG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMRNGPAQTRVSSSSSHQEATLAMGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS", 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"id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "E1B8Y4", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "E1B8Y4", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4" } ], "pmid": "" }, { "name": "alpha-L-arabinofuranosidase activity", "id": "GO:0046556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046556", "evidence": [ { "database": "UniProtKB", "id": "E1B8Y4", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-arabinose metabolic process", "id": "GO:0046373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046373", "evidence": [ { "database": "UniProtKB", "id": "E1B8Y4", "url": "https://www.uniprot.org/uniprotkb/E1B8Y4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1316, "end_pos": 1318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1468, "end_pos": 1470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1602, "end_pos": 1604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2069, "end_pos": 2071, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2309, "end_pos": 2311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2446, "end_pos": 2448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2503, "end_pos": 2505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2594, "end_pos": 2596, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2725, "end_pos": 2727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2756, "end_pos": 2758, "annotation": 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"E1B906-1", "uniprot_ac": "E1B906", "uniprot_id": "E1B906_BOVIN", "mass": { "chemical_mass": 50224.0, "monoisotopic_mass": 50224.0 }, "refseq": { "ac": "NP_001192753", "name": "SET domain-containing protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192753" }, "gene_names": [ { "name": "SETD4", "type": "recommended", "evidence": [ { "id": "E1B906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ] }, { "name": "SETD4", "type": "synonym", "evidence": [ { "id": "NP_001192753", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192753" } ] } ], "protein_names": [ { "name": "SET domain-containing protein 4", "type": "recommended", "evidence": [ { "id": "E1B906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B906/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.364", "type": "synonym", "evidence": [ { "id": "E1B906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B906/entry#names_and_taxonomy" } ] }, { "name": "SET domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "NP_001192753", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192753" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SETD4", "url": "https://www.uniprot.org/uniprotkb/E1B906", "locus": { "chromosome": "1", "start_pos": 148318438, "end_pos": 148340888, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018682", "url": "https://www.ensembl.org/id/ENSBTAG00000018682" } ] } } ], "crossref": [ { "id": "E1B906", "url": "https://alphafold.ebi.ac.uk/entry/E1B906", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018682", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018682", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19177", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19177", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540440", "url": "https://www.ncbi.nlm.nih.gov/gene/540440", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540440", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540440", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISHMKDE", "url": "https://omabrowser.org/oma/group/ISHMKDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B906", "url": "https://www.orthodb.org/?gene=E1B906", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13271:SF151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13271:SF151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192753", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192753", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "51736", "url": "https://www.rhea-db.org/rhea/51736", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60264", "url": "https://www.rhea-db.org/rhea/60264", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60268", "url": "https://www.rhea-db.org/rhea/60268", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60344", "url": "https://www.rhea-db.org/rhea/60344", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60348", "url": "https://www.rhea-db.org/rhea/60348", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "61992", "url": "https://www.rhea-db.org/rhea/61992", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B906-1", "url": "https://www.uniprot.org/uniprotkb/E1B906-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNGGGRTSRIRRRKLFTSSESRGVNESYKPEFIELKKWLKDRRFEDTTLIPAHFPGTGRGLMSKTSLQEGQTIISLPESCLLTTDTVIRSYLGAYIAKWQPPPSPLLALCTFLVSEKHAGDRSPWKPYLEVLPKAYTCPVCLEPEVVNLLPNPLKTKAWEQRSHVWEFFSSSRGFFSSLQPLFSEAVETIFSYRALRWAWCAVNTRAVYMKRPPLLCLSPEPDTCALAPYLDLLNHSPDVQVKAAFNEETRCYEIRTATRCGKHKEVFICYGPHDNHRLLLEYGFVCVSNPHACVYVSKDILVKYLPSTAKQMNKKISILEDHDFTENLTFGWDGPSWRLLTALKLLCLEAEEFTCWKKVLLGEIISDTNEKASLDVAQKICHYFIEETHAVLRKVSRMKDEEVALMNQLTLVETLRTEELKILQASAKALTTLQTAFS", "length": 440, "header": "tr|E1B906-1|E1B906_BOVIN Isoform 1 of SET domain-containing protein 4 OS=Bos taurus OX=9913 GN=SETD4 PE=3 SV=1 CANONICAL=E1B906-1" }, "isoforms": [ { "isoform_ac": "E1B906-1", "url": "https://www.uniprot.org/uniprotkb/E1B906/entry#E1B906-1", "sequence": { "sequence": "MKNGGGRTSRIRRRKLFTSSESRGVNESYKPEFIELKKWLKDRRFEDTTLIPAHFPGTGRGLMSKTSLQEGQTIISLPESCLLTTDTVIRSYLGAYIAKWQPPPSPLLALCTFLVSEKHAGDRSPWKPYLEVLPKAYTCPVCLEPEVVNLLPNPLKTKAWEQRSHVWEFFSSSRGFFSSLQPLFSEAVETIFSYRALRWAWCAVNTRAVYMKRPPLLCLSPEPDTCALAPYLDLLNHSPDVQVKAAFNEETRCYEIRTATRCGKHKEVFICYGPHDNHRLLLEYGFVCVSNPHACVYVSKDILVKYLPSTAKQMNKKISILEDHDFTENLTFGWDGPSWRLLTALKLLCLEAEEFTCWKKVLLGEIISDTNEKASLDVAQKICHYFIEETHAVLRKVSRMKDEEVALMNQLTLVETLRTEELKILQASAKALTTLQTAFS", "length": 440, "header": "tr|E1B906-1|E1B906_BOVIN Isoform 1 of SET domain-containing protein 4 OS=Bos taurus OX=9913 GN=SETD4 PE=3 SV=1 CANONICAL=E1B906-1" }, "locus": { "chromosome": "1", "start_pos": 148337769, "end_pos": 148318454, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024868.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024868.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024868.4", "url": "https://www.ensembl.org/id/ENSBTAP00000024868.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:540440", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540440", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YPK3-1", "protein_name": "SET domain-containing protein 4", "gene_name": "SETD4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKKSRGRTSRKRRRKRLQKFMYGVNCSHKLEYIKLKKWLKDRGFGDSSLRPAQFWGTGRGLMTTKALQAGELVISLPEKCLVTTTTVLNSCLGEYIMKWKPPVSPLIALCTFLIAEKHAGERSLWKPYLDVLPKTYSCPVCLEQDVVQLLPEPLRKQAQEQRTAVHELYMSSKAFFSSLQSLFAENTATIFNYSALEWAWCTINTRTIYMKHSQRECFSLEPDVYALAPYLDLLNHSPNVQVKAAFNEQSRNYEIQTNSQCKKHEEVFICYGPHDNQRLLLEYGFVAVDNPHSSVYVSSDTLLKYFPPLDKQKNAKLSILKDHDLLENLTFGWDGPSWRLLTALKVLSLGGDEFTCWRRALLGDVISARNEQQALNITTKICHFLIEETQHVLLQISQMKRDKENLKEQLTLVEALRLEDLKILQKSAEILCNLNVTTI", "length": 439 }, "evidence": [ { "id": "E1B906", "url": "https://omabrowser.org/oma/group/E1B906/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LLN1-1", "protein_name": "SET domain-containing protein 4", "gene_name": "SETD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKKGGGRTSRIRRRKRFGKAESRGVNESYKPEFIELKKWLKDRNFEDTNLIPARFPGTGRGLMSKTSLQEGQLVIALPESCLLTTDTVLRSYLGPYIAKWQPPPSPLLALCTFLVSEKHAGDQSPWKPYLEVLPKTYTCPVCLEPEVVNLLPGPLKSKAREQRTRVWEFFSSSRDFFSSLQPLFPEAVESIFSYSALLWAWCTVNTRAVYMKQRPRQCFSTEPDTCALAPYLDLLNHSPAVQVKAAFNEESRCYEIRTGTSCRKHEEVFICYGPHGSHRLLLEYGFVSPRNPHACVYVPKDILVKYLPSTDKQMNKKISILKDHDFIENLTFGWDGPSWRLLTALKLLCLGAEDFTCWKKVLLGEVISDAHEKTSLDIAQKICHYFIEETNAMLQKISHMKDEDVALINQLTLVETLRTEELKILQASTEILAGLQTAFM", "length": 440 }, "evidence": [ { "id": "E1B906", "url": "https://omabrowser.org/oma/group/E1B906/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P58467-1", "protein_name": "SET domain-containing protein 4", "gene_name": "Setd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRRRGRTERARKRRRRSSGSRAVNESYRSEFIELRKWLKERKFEDTDLVPASFPGTGRGLMSKASLQEGQVMISLPESCLLTTDTVIRSSLGPYIKKWKPPVSPLLALCTFLVSEKHAGCRSLWKSYLDILPKSYTCPVCLEPEVVDLLPSPLKAKAEEQRARVQDLFTSARGFFSTLQPLFAEPVDSVFSYRAFLWAWCTVNTRAVYLRSRRQECLSAEPDTCALAPFLDLLNHSPHVQVKAAFNEKTRCYEIRTASRCRKHQEVFICYGPHDNQRLLLEYGFVSVRNPHACVPVSADMLVKFLPAADKQLHRKITILKDHGFTGNLTFGWDGPSWRLLTALKLLCLEAERFTSWKKVLLGEVISDTNEKTSLGVAQKICSDVIEETHAVLRKVSDMKEGTVSLRSQLSLVEALRMEELRILQASAEILSGLLAPFS", "length": 439 }, "evidence": [ { "id": "E1B906", "url": "https://omabrowser.org/oma/group/E1B906/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVD3-1", "protein_name": "SET domain-containing protein 4", "gene_name": "SETD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGRGLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSPLLALCTFLVSEKHAGHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQRAHVQEFFASSRDFFSSLQPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPHVQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSREILVKYLPSTDKQMDKKISILKDHGYIENLTFGWDGPSWRLLTALKLLCLEAEKFTCWKKVLLGEVISDTNEKTSLDIAQKICYYFIEETNAVLQKVSHMKDEKEALINQLTLVESLWTEELKILRASAETLHSLQTAFT", "length": 440 }, "evidence": [ { "id": "E1B906", "url": "https://omabrowser.org/oma/group/E1B906/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "pmid": "" }, { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "pmid": "" }, { "name": "histone H3K36 methyltransferase activity", "id": "GO:0046975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046975", "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "pmid": "" }, { "name": "histone H3K4 monomethyltransferase activity", "id": "GO:0140945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140945", "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "E1B906", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "51736", "name": "", "equation": "L-lysyl-[protein] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2YDJ8-1", "Q0P585-1", "P0DPE2-1", "A4FV98-1", "E1BI64-1", "A5PK19-1", "A6QP81-1", "E1B906-1", "G3X834-1", "F1MDT8-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1", "A0ABI0NZS0-1" ], "evidence": [ { "id": "51736", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51736" } ] }, { "id": "60264", "name": "", "equation": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TQW6-1", "E1B9N8-1", "F1MHA1-1", "E1BKN0-1", "E1B906-1", "F1N6Y5-1", "E1BLX2-1", "A0ABI0NZS0-1" ], "evidence": [ { "id": "60264", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60264" } ] }, { "id": "60268", "name": "", "equation": "N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MHA1-1", "E1B906-1", "E1BKN0-1", "F1N6Y5-1", "E1BLX2-1" ], "evidence": [ { "id": "60268", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60268" } ] }, { "id": "60344", "name": "", "equation": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMB9-1", "Q2YDJ8-1", "Q29RP8-1", "A6QPM3-1", "E1B906-1", "G3X834-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1" ], "evidence": [ { "id": "60344", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60344" } ] }, { "id": "60348", "name": "", "equation": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMB9-1", "A0A3Q1M6A7-1", "Q29RP8-1", "E1B906-1", "G3X834-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1" ], "evidence": [ { "id": "60348", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60348" } ] }, { "id": "61992", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMB9-1", "A0A3Q1M6A7-1", "Q29RP8-1", "E1B906-1" ], "evidence": [ { "id": "61992", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61992" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LMB9", "gene_name": "KMT5B", "activity": [ { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1LMB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB9" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1LMB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB9" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A3Q1LMB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB9" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A3Q1LMB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB9" } ] } ] }, { "uniprot_ac": "A0A3Q1M6A7", "gene_name": "KMT5C", "activity": [ { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1M6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6A7" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1M6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6A7" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A3Q1M6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6A7" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A3Q1M6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6A7" } ] } ] }, { "uniprot_ac": "A0A3Q1MPX3", "gene_name": "PRDM9", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] } ] }, { "uniprot_ac": "A0AAA9SSU7", "gene_name": "", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", 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"", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 768, "start_aa": "Thr", "end_pos": 768, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr768", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 810, "start_aa": "Thr", "end_pos": 810, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr810", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:518794", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518794", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q63560-1", "protein_name": "Microtubule-associated protein 6", "gene_name": "Map6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPAPPQPGLAPPSRAVAIETQPAQGESDAVARATGPAPGPSGDRETAAAPGRSGLGLGAASGSTSGSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQIPATSQPSPPVLGMPKRRPQSQERGPIQLSADARDPEGAGGAGVPAAGKASGADQRDTRRKAGPAWMVTRTEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEETPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEETPLPPAQSQTQEGGPAAGKASGADERDTRRKAGPAWMVRRSEGHEQTTAAHAQGTGPEGGKGRAVADALNRQIREEVTSTVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVVDRRRIRSLYSEPFKESPKVEKPSVQSSKPKKTSTSQKPLRKAKDKQVASGQAAKKKTTESPSATKPDDKEQSKEMNNKLAEAKESRVKPTSDKNQGPVAKEPHKDQGPVAPGLPKGQGPAVQEPLKDQGPMVPGLPKDQAPVVPGSLKGQSPTAPGPPKDQGAVLLGPMKDLGPVAPASVKDQDHMASELLKNKDSVPLAPAKAQSPLLPEPLKNQSPVVPARAKDQSFPAPAPTPLKDPGPVIPEPEKDGAPMVPERRKDQNASIMASLKNEAPVASESVKNQGLGGPEPAKDTGTDLKGHGSVFVAPVKSQGPVVPEPTKGQDPIIPALAKDQGPILPEPPKNQGPPVVLGPIKNQDPVIPVPLKGQDPVVPAPTKDPGPTAPDPLKSQGPRGPQLPTVSPSPPVMIPTVPHAEYIEGSP", "length": 952 }, "evidence": [ { "id": "E1B919", "url": "https://omabrowser.org/oma/group/E1B919/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TSJ2-1", "protein_name": "Microtubule-associated protein 6", "gene_name": "Map6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPAPLQPALAPPSRAVAIETQPAQGESDAVARATGPAPGPSVDRETVAAPGRSGLGLGAASASTSGSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQIPATSQPSQPVLGVPKRRPQSQERGPMQLSADARDPEGAGGAGVLAAGKASGVDQRDTRRKAGPAWMVTRNEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRSEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEETPLPPAQSQTQEGGPAAGKASGADERDTRRKAGPAWMVRRSEGHEQTPAAHAQGTGPEGGKGRAVADALNRQIREEVASTVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEANKPSAADNKAMDRRRIRSLYSEPFKECPKVEKPSVQSSKPKKTSTSHKPPRKAKDKQVVSGQAAKKKTTEGPSATKPDDKEQSKEMNNKLAEAKESRVKPTSDASKNRGPVTKEPHKDQGSVAPGLPKGQEPLKDQGPVVPGLPKDQVPVVPGSLKGQSPTAPGPTKDQGAVLLGPVKDLGPVAPAPIKVQDHIASELLKNKDSVPLAPAKAQSPLLPEPLKNQSPVVPASTKDQSFPTPAPRKDPGPVIPEPEKDRAPTVPERRKDQHVSIMASLKNEAPMVPESVKNQGLAGPELVKDTGTDTTAPRYLKGHDSVFVAPVKNQGPVIPEPVKSQDPIIPALAKDQGPMLPEPPKNQSPVVLGPIKNQDPIIPVPLKGQDPLVPAPTKDQGPTAPDPLKTQGPKGTQLPTVSPSPPVMIPTVPHTEYIEGSP", "length": 906 }, "evidence": [ { "id": "E1B919", "url": "https://omabrowser.org/oma/group/E1B919/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JE9-1", "protein_name": "Microtubule-associated protein 6", "gene_name": "MAP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPRVMIPTAPHTEYIESSP", "length": 813 }, "evidence": [ { "id": "E1B919", "url": "https://omabrowser.org/oma/group/E1B919/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi-associated vesicle", "id": "GO:0005798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005798", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" }, { "name": "positive regulation of axonogenesis", "id": "GO:0050772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050772", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" }, { "name": "cytoskeleton-dependent intracellular transport", "id": "GO:0030705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030705", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" }, { "name": "regulation of microtubule cytoskeleton organization", "id": "GO:0070507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070507", "evidence": [ { "database": "UniProtKB", "id": "E1B919", "url": "https://www.uniprot.org/uniprotkb/E1B919" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B919-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 912, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B919-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B919" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 101, 270, 508, 649, 725, 768, 810 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 711, "end_pos": 713 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 7 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 7 }, { "field": "exact_o_linked_sites", "count": 7 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 7 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 7 }, { "field": "exact_o_linked_sites", "count": 7 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1B934-1", "uniprot_ac": "E1B934", "uniprot_id": "E1B934_BOVIN", "mass": { "chemical_mass": 21132.0, "monoisotopic_mass": 21132.0 }, "refseq": { "ac": "XP_002684630", "name": "melanocortin-2 receptor accessory protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002684630" }, "gene_names": [ { "name": "MRAP", "type": "recommended", "evidence": [ { "id": "E1B934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ] }, { "name": "MRAP", "type": "synonym", "evidence": [ { "id": "XP_002684630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002684630" } ] } ], "protein_names": [ { "name": "Melanocortin 2 receptor accessory protein", "type": "synonym", "evidence": [ { "id": "E1B934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B934/entry#names_and_taxonomy" } ] }, { "name": "melanocortin-2 receptor accessory protein", "type": "synonym", "evidence": [ { "id": "XP_002684630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002684630" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MRAP", "url": "https://www.uniprot.org/uniprotkb/E1B934", "locus": { "chromosome": "1", "start_pos": 3183412, "end_pos": 3197661, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000023718", "url": "https://www.ensembl.org/id/ENSBTAG00000023718" } ] } } ], "crossref": [ { "id": "E1B934", "url": "https://alphafold.ebi.ac.uk/entry/E1B934", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000023718", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000023718", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505743", "url": "https://www.ncbi.nlm.nih.gov/gene/505743", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505743", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505743", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1B934", "url": "https://www.orthodb.org/?gene=E1B934", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28675:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28675:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15183", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15183", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002684630", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002684630", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B934-1", "url": "https://www.uniprot.org/uniprotkb/E1B934-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGPPPDLPPSPTALISEEALSSETHRHTWMILHKSAGPSPGELGAAPEGPPGSDAGMANRTNISAPYYSYEYYLDYLDLMPVDEKKLRANKHSIVIAFWVSLAAFVVFLFLILLYMSWSGSPQTRNATQQPPTCSWNLGLNLPLCIWRQPSTPGPHRARSRNQTPEHPGCPAATTREPLNLSTPGTILLSSGN", "length": 194, "header": "tr|E1B934-1|E1B934_BOVIN Isoform 1 of Melanocortin 2 receptor accessory protein OS=Bos taurus OX=9913 GN=MRAP PE=3 SV=4 CANONICAL=E1B934-1" }, "isoforms": [ { "isoform_ac": "E1B934-1", "url": "https://www.uniprot.org/uniprotkb/E1B934/entry#E1B934-1", "sequence": { "sequence": "MSGPPPDLPPSPTALISEEALSSETHRHTWMILHKSAGPSPGELGAAPEGPPGSDAGMANRTNISAPYYSYEYYLDYLDLMPVDEKKLRANKHSIVIAFWVSLAAFVVFLFLILLYMSWSGSPQTRNATQQPPTCSWNLGLNLPLCIWRQPSTPGPHRARSRNQTPEHPGCPAATTREPLNLSTPGTILLSSGN", "length": 194, "header": "tr|E1B934-1|E1B934_BOVIN Isoform 1 of Melanocortin 2 receptor accessory protein OS=Bos taurus OX=9913 GN=MRAP PE=3 SV=4 CANONICAL=E1B934-1" }, "locus": { "chromosome": "1", "start_pos": 3197462, "end_pos": 3183532, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032472.6", "url": "https://www.ensembl.org/id/ENSBTAT00000032472.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032404.6", "url": "https://www.ensembl.org/id/ENSBTAP00000032404.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505743", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505743", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "pmid": "" }, { "name": "regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0106070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106070", "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "type 3 melanocortin receptor binding", "id": "GO:0031781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031781", "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "pmid": "" }, { "name": "type 4 melanocortin receptor binding", "id": "GO:0031782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031782", "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "pmid": "" }, { "name": "type 1 melanocortin receptor binding", "id": "GO:0070996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070996", "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "pmid": "" }, { "name": "corticotropin hormone receptor binding", "id": "GO:0031780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031780", "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "pmid": "" }, { "name": "type 5 melanocortin receptor binding", "id": "GO:0031783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031783", "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "pmid": "" }, { "name": "signaling receptor regulator activity", "id": "GO:0030545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030545", "evidence": [ { "database": "UniProtKB", "id": "E1B934", "url": "https://www.uniprot.org/uniprotkb/E1B934" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B934-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 194, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B934-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B934" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 60, "end_pos": 62 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1B941-1", "uniprot_ac": "E1B941", "uniprot_id": "E1B941_BOVIN", "mass": { "chemical_mass": 54340.0, "monoisotopic_mass": 54340.0 }, "refseq": {}, "gene_names": [ { "name": "PMPCB", "type": "recommended", "evidence": [ { "id": "E1B941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B941" } ] } ], "protein_names": [ { "name": "Mitochondrial-processing peptidase subunit beta", "type": "recommended", "evidence": [ { "id": "E1B941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B941/entry#names_and_taxonomy" } ] }, { "name": "3.4.24.64", "type": "synonym", "evidence": [ { "id": "E1B941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B941/entry#names_and_taxonomy" } ] }, { "name": "Beta-MPP", "type": "synonym", "evidence": [ { "id": "E1B941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B941/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Preferentially, cleaves after an arginine at position P2. Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis.", "evidence": [ { "database": "UniProtKB", "id": "E1B941", "url": "https://www.uniprot.org/uniprotkb/E1B941#function" }, { "database": "UniProtKB", "id": "ARBA00045433", "url": "https://www.uniprot.org/uniprotkb/ARBA00045433#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B941", "url": "https://www.uniprot.org/uniprotkb/E1B941" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PMPCB", "url": "https://www.uniprot.org/uniprotkb/E1B941", "locus": { "chromosome": "4", "start_pos": 44531440, "end_pos": 44517271, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006876", "url": "https://www.ensembl.org/id/ENSBTAG00000006876" } ] } } ], "crossref": [ { "id": "E1B941", "url": "https://alphafold.ebi.ac.uk/entry/E1B941", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006876", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006876", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1B941", "url": "https://www.orthodb.org/?gene=E1B941", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11851", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11851", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11851:SF103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11851:SF103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00675", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00675", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8949664", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8949664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1B941", "url": "https://www.uniprot.org/uniprotkb/E1B941", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B941-1", "url": "https://www.uniprot.org/uniprotkb/E1B941-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "TMAAAAVARAVLFSAARRRLCGFTERLLIGGAAGRSLYFGGNRLRSTQAAAQVVLNVPETRVTCLENGLRVASEDSGLATCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSINRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGESLSTHKGEIPALPLCKFTGSEIRVRDDKMPLAHLAVAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTDTGLWGIYMVCEPATVADMLHVVQKEWMRLCTSVTESEVARAKNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAEIIREVCTKYIYDKSPAVAAVGPIEQLPDFNQICSNMRWLHD", "length": 491, "header": "tr|E1B941-1|E1B941_BOVIN Isoform 1 of Mitochondrial-processing peptidase subunit beta OS=Bos taurus OX=9913 GN=PMPCB PE=3 SV=3 CANONICAL=E1B941-1" }, "isoforms": [ { "isoform_ac": "E1B941-1", "url": "https://www.uniprot.org/uniprotkb/E1B941/entry#E1B941-1", "sequence": { "sequence": "TMAAAAVARAVLFSAARRRLCGFTERLLIGGAAGRSLYFGGNRLRSTQAAAQVVLNVPETRVTCLENGLRVASEDSGLATCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSINRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGESLSTHKGEIPALPLCKFTGSEIRVRDDKMPLAHLAVAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTDTGLWGIYMVCEPATVADMLHVVQKEWMRLCTSVTESEVARAKNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAEIIREVCTKYIYDKSPAVAAVGPIEQLPDFNQICSNMRWLHD", "length": 491, "header": "tr|E1B941-1|E1B941_BOVIN Isoform 1 of Mitochondrial-processing peptidase subunit beta OS=Bos taurus OX=9913 GN=PMPCB PE=3 SV=3 CANONICAL=E1B941-1" }, "locus": { "chromosome": "4", "start_pos": 44531308, "end_pos": 44517274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004922.8", "url": "https://www.ensembl.org/id/ENSBTAT00000004922.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004922.7", "url": "https://www.ensembl.org/id/ENSBTAP00000004922.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-8949664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8949664", "resource": "Reactome", "description": "Processing of SMDT1" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "E1B941", "url": "https://www.uniprot.org/uniprotkb/E1B941" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1B941", "url": "https://www.uniprot.org/uniprotkb/E1B941" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein processing involved in protein targeting to mitochondrion", "id": "GO:0006627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006627", "evidence": [ { "database": "UniProtKB", "id": "E1B941", "url": "https://www.uniprot.org/uniprotkb/E1B941" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial processing peptidase complex", "id": "GO:0017087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017087", "evidence": [ { "database": "UniProtKB", "id": "E1B941", "url": "https://www.uniprot.org/uniprotkb/E1B941" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-8949649", "name": "PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KJI7-1", "E1B941-1" ], "evidence": [ { "id": "R-BTA-8949649", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8949649" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1B941", "gene_name": "PMPCB", "activity": [ { "ec_number": "3.4.24.64", "activity": "Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.", "evidence": [ { "id": "E1B941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B941" } ] }, { "ec_number": "3.4.24.64", "activity": "", "evidence": [ { "id": "E1B941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B941" } ] } ] }, { "uniprot_ac": "Q2KJI7", "gene_name": "AFG3L2", "activity": [ { 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"id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:528343", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528343", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNIQSSE", "url": "https://omabrowser.org/oma/group/MNIQSSE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B952", "url": "https://www.orthodb.org/?gene=E1B952", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377030", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377030", "database": "RefSeq", 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{ "uniprot_canonical_ac": "E1B958-1", "uniprot_ac": "E1B958", "uniprot_id": "E1B958_BOVIN", "mass": { "chemical_mass": 482210.0, "monoisotopic_mass": 482210.0 }, "refseq": { "ac": "XP_005212573", "name": "centrosome-associated protein ALMS1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212573" }, "gene_names": [ { "name": "ALMS1", "type": "recommended", "evidence": [ { "id": "E1B958", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B958" } ] }, { "name": "ALMS1", "type": "synonym", "evidence": [ { "id": "XP_005212573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212573" } ] } ], "protein_names": [ { "name": "ALMS1 centrosome and basal body associated protein", "type": "synonym", "evidence": [ { "id": "E1B958", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B958/entry#names_and_taxonomy" } ] }, { "name": "centrosome-associated protein ALMS1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005212573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212573" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B958", "url": "https://www.uniprot.org/uniprotkb/E1B958" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ALMS1", "url": "https://www.uniprot.org/uniprotkb/E1B958", "locus": { "chromosome": "11", "start_pos": 10889044, "end_pos": 11079997, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011172", "url": "https://www.ensembl.org/id/ENSBTAG00000011172" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011172", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011172", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "533055", "url": "https://www.ncbi.nlm.nih.gov/gene/533055", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:533055", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533055", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYSQRDQ", "url": "https://omabrowser.org/oma/group/PYSQRDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B958", "url": "https://www.orthodb.org/?gene=E1B958", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21553", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21553", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21553:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21553:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15309", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15309", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005212573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1B958", "url": "https://www.uniprot.org/uniprotkb/E1B958", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B958-1", "url": "https://www.uniprot.org/uniprotkb/E1B958-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPEDLPWPGELEEEEEEEGAENLDEDEVVMVEEMEEEERREPEADFNYESQRRESTDEEDDEEAKAWLQAHPGATLPQASLPRHRYSESELTSPGKVVPLTCHLWQQPLYHNNSGTQISDTNVASLENIAPWGSGDDQRTESWHCLPQEMDSSCTLDTAQTGFNMREKGTEVTDFTSLEEGILTQSENQGKDPNRDLLCSPLLVLQDNFASPDLPLLTCLTERQEFGPDSLFHQSELDFAPLRGIPGKSEDTEWFSRPSEVSEALFQAASGVASDLVNSCFSRSQHPLIGSTAVKSQHSLLTPEQGTKEETASSNTLDLKTCEDSGNYDAVYSYMSWETQQVMQEPATNLADKDHVSFSTASDISDEYINPRGSDNFDASYLYAQYGNQGTLQQSEKYLASKDHDSYSDSSDTIDRNKIPKESDNFSFSNMPWSKQGASHHPEIYLISKDHVSFPHEVAPHFNNKMPHSFWHCLLGSGGSEVPLMSDSHYFESVCLRAPVENEVKQKVDSLESYKSNEEDLGKGLSQCFEVKENRNTLVFSEVHPRSSEIQYIENVVVPDNSVEVSEAHILSRGLDTSTMEISGGPLQTIKFNSNETSEQLYFQEERNQEATSVFDGENVGAMKNVAFRAVIASIEPSKKESTVNEIQTDINKSLTNDSQESEPKSPDPSLLNYDENLLFDKLKRPRYQSTPGVFESGASKSLYKKDDGDSSLYWHHNLNSIPSASQEILIKPLSLSPELKPSSSLSEKSLKQAVGLGRTWSTLFQYGIDNEQFLPLGKIKSVSALDLAEKLGSSNIIYPMKVWTSDSLVSQDLKQHSFEEADSSNCILGKTVNSSYIIEGPSAAVGSGFSANLVACDAKSQGALPVMSNAPLIAVGQKTLLKADTGQGEIPRPLGARSSFTIHTIMQNDSYFVEGLQGKAESDICTLDDDTECCSVDENAVVCSKRQEICDQGDLTGECVELAGLENLLDDLEICDSSLQWQSTVRLPSKEDSSFEDSVCPSNTDINESFSSVLPPFVPHEPTGDLEYHSSNLRMLRVSPDTVSRTVRHLTGDTSKGGIAEIPQSTFKPGITTFPEDSDTVSPLSLSPEDFPQLAGRSPQVKNIGEYTDTVNQQTLTDSRLTEETLKISAIPGLADQKTGIAAVSSSSYSQRGKPNIFYPQALPDSHLTEEALKVGAVPGLGDQKTGVSTVPPSSYSLGEKHSIFYPQALPDSHQTEESRNVSVLPGLADQKTGKPIVPASSYSVGEEPGIFYHQVLPDSQPPEEALKVLASPRPVDQKSGLPTPSSTYSYGEKPHIFYQQTLPDTHPSEQTLKVSAAPGLAEQKTGVPAVTSASYPHKEKPSIFYQPELPNRRLIQEAHQVSAAPVLVEQKAGISIVPSTSYSHREKPRVVYQQELPESHLIQEVQQVSAAPGLAEQKTGIPTVPSTSYSHREKPSIVYQQELSDSQLIEQSQKVSSVPGLAEQKTGIPTVPSTSYSHREKSSIFYQQELPDSHLTQEVQQVSTAAGPLEQKTGIPTVPSTSYSHREKPHIFYQQELPESHLTEQAHKVSSVPGLAEQKTGISTVASTSYSHREKPSILYQQELPDIHVIHEVPEVSSVPGLAEQKARIPVIPSTTYSHREKPSILYQQELPDSHLTEQVQKASAAPGPAEQKTGIPIITSASYSYREKPIIFYQQDLPDSHLTKEAQKVPTVSGLAHQKSGIPIVPPAFYSHGGKTSLFYQQELPDSHLSDQTQKISAIPGPVDQNTGIQTAPSSSYSYREKPIAFYQQELPGRLLTEEVLKVSALPRTTDQNTGIITGSSQSYLFGEKPSGLFYQHVLPDGSLTEEALKVSPASRPSDQKTGVLLLPASSYSHREKPGIFYPQALPSSHLSEETLKDSAVLGPADQKTGTSEPSGSYSHREKSSIFYQQELPDSHITGEALKISGVSGTGDQKTGIPIVTSPSYSQREKPIVFYQQVLPDTHLTKEALNVSNAPAQADQKTGIPIVTSPSFSYNEKPIIFYQQALPDSQLTVEALKVSDVPGPSDQKTGIPTVPPSSYSYREKPIISYQQESPDLTQVALKVFEVPGPADQKIGIPPVTSASYSYGEKPIISYQQELPDANENALRGLGVPRQADQTVGVRIVPPASYSHRESPIFSYQQELPDLTEEALKVFALPGPADQNAEIPIGPSSSYSHKERLKTSPDDQKTELPSTPSGSYSHREKPKTSTIIGPADQKTPLLTGFPNSYSQRVKPSIFFQQQLGDRHQSGDILKISSVAEPTDVNSQISIPLSASYSHSEKSSVFYPKELPDKHLREDSLKVSTVPGPADKKTVLPAVPPSSFSHREKPAILYHQDFPERHLTEDNLKFSSSLEQADQNNGLSTVPPGTYSHSEKHKPVSHHVQRLTDNLDSSHTSVISNNMPLNSQADGRVVINKPESSGFEDVGSEEIRDTENSSRTLKEIQTLLMEAENIALRRYNVPAPLVPFRDVSDISFIQSKKMVCFKEPLTTDESNDDLSQRQPFTEESSSNKCIQKDISTQTNLKCQRGIENWEFISSTTVRSPLQEAEGKARVAFDETFKQYKAARSVMRSEPEEYSRTIGNKIVIPMMTIIKSDSSSDASSCSWDSNSLESVSDVLLNFFPYSSPKTSMTDSREEEGVLESDDGGGSSVDSLAAHVKNLLKCESSLNHAKQILKNAEEEESRVRARAWNLKFNMAHDYGYSISELNEDDRRKVEEIKAKLFGQGRTTDLSKDLQSPRGIGYKPEAVCSHIIIESHEKGCFRTLTAERPRLDSHPCVFRSAEPSEIVRGQRSPSSWRTRHINLSKSLDQNNSQFKVWNSLQLQSHSPFQNFISEDLEISKGLRMPFHEKLDPWLSELVEPACMPPEEMDCHSSSQMLPPEPMKKFTTSITFSSHRHSKCFSDSSFLKVGVTEGSQCSGASVGVVNSHFTEEQNPPRDLKQRTSSPSSLKIISQSPDKAVTILAENSSQSQKLSVEHSYQEEKPLEKSDFKSSHPKPSASANDSNFKEVHFSDNHTLISMGRPNSTLEVKEKNVTITADLPSHIFLEQEVFEQSKAPHADHHVRKHHSPPPQRQDYVAPNLPCRIFLEKRELFKQSKAPHVDQLRENHSPLPQSQDYIASDLPSSIFLEQRQLFEQSKAPNVDHHLRKLHSPLPQSQDSVVEKNNEHKPKLHISDVIDVEAKFSDVVSPSVPNQCTVVTSASTPPSNRKALSCIRITLCPKTPSKLDSGNLDKRFHSLDPATKTRMNSEFNSDLQTISSRSLEPTSKLLISKPVAQNQESLGFLGPKSSSDFQVVQSPLPDSNVITQDLKTIPYQNSQIVTSRQTQVNSSDLEEYSNPEGTPVSADRSPEEIKSPFSPFSGKLSSDAVTQITTESPGKATFSSEIFVNAEDRGHEIPELNTQKSGNIPVKFASSSSVQQITVPHGTDGQPLLLPYKPSGSTKMYYVPQLTQIPSSLDSKSDTTIESSHSGSNDAIAPDFPAQVLGTRDDDLADTVNIKHKEGIYSKRAVTKASLSMGKKPFQKDNADAHVQVLITGDEDLSDKNQEKEIYTKKAVTKIAGSEEKESLEKDTTGSSTAAASQHSTQDTKTDSLPDTKAIKQKEEVHSKRKVPKEAWSEEKKALQIDIAESRCHSEFENTTHSVFRSAKFYFHHPVHLSSDQDFCHESLGRSVFMRHSWKDFFQHHPDKQREYTCLPSPCQHMEKTKTDYTRIESLSINVNLENKELKRATQSQARDFPKSDKQINDLKRDPKATPELTSEHTVSLNELWNRYQERQKQQKPEVSAKKELSLVERLDRLAKLLQHPITHSLQPSESTQDDSRGEQDAKEWSDKQQQQKNKLQKKKRYKSLEKCHKNTGDLKKNKILSAHQAGRPNQIKIEQFKFDKYILRKHPGFHYINNTSSDSRHSEDSELLTDTTTNILSTTTSPVESDILTQTDKEMTLHERSSSISTIDTARLIHAFGHERVCLSPRRIKLYSSITDHQRRYLEKRSKKNKKALNTGYPQITSEHTRRKHIQVTDHVSSDSVSSSTSSFWSSNSTLCNKQNTHMLNKGVQAGNLEIVSGVRKNTRDVGMTFPTPSSSEARVEEDSDVTSWSEEKIEEKRLLTSYLGDKKLKKNKKTCCEGVSWFVPVENMKSGPKKENMPKLHGPGVSWFAPITNTKPWREPLREQNWQGQHMDSHSSLAGPGKEPLKPFVRATLQESLQLHRPDFISRSGERIKRLKLIVQERKLQNMLQSEREALFNTVQEWQGYRDPVHLLRKRGFLAAQKKRPVGKKEMIQRSKRIYEQLPEVQKKREEEKRRSEYKSYRLRAQLYKKKVTNQLLGRKVPWD", "length": 4331, "header": "tr|E1B958-1|E1B958_BOVIN Isoform 1 of ALMS1 centrosome and basal body associated protein OS=Bos taurus OX=9913 GN=ALMS1 PE=4 SV=3 CANONICAL=E1B958-1" }, "isoforms": [ { "isoform_ac": "E1B958-1", "url": "https://www.uniprot.org/uniprotkb/E1B958/entry#E1B958-1", "sequence": { "sequence": "MEPEDLPWPGELEEEEEEEGAENLDEDEVVMVEEMEEEERREPEADFNYESQRRESTDEEDDEEAKAWLQAHPGATLPQASLPRHRYSESELTSPGKVVPLTCHLWQQPLYHNNSGTQISDTNVASLENIAPWGSGDDQRTESWHCLPQEMDSSCTLDTAQTGFNMREKGTEVTDFTSLEEGILTQSENQGKDPNRDLLCSPLLVLQDNFASPDLPLLTCLTERQEFGPDSLFHQSELDFAPLRGIPGKSEDTEWFSRPSEVSEALFQAASGVASDLVNSCFSRSQHPLIGSTAVKSQHSLLTPEQGTKEETASSNTLDLKTCEDSGNYDAVYSYMSWETQQVMQEPATNLADKDHVSFSTASDISDEYINPRGSDNFDASYLYAQYGNQGTLQQSEKYLASKDHDSYSDSSDTIDRNKIPKESDNFSFSNMPWSKQGASHHPEIYLISKDHVSFPHEVAPHFNNKMPHSFWHCLLGSGGSEVPLMSDSHYFESVCLRAPVENEVKQKVDSLESYKSNEEDLGKGLSQCFEVKENRNTLVFSEVHPRSSEIQYIENVVVPDNSVEVSEAHILSRGLDTSTMEISGGPLQTIKFNSNETSEQLYFQEERNQEATSVFDGENVGAMKNVAFRAVIASIEPSKKESTVNEIQTDINKSLTNDSQESEPKSPDPSLLNYDENLLFDKLKRPRYQSTPGVFESGASKSLYKKDDGDSSLYWHHNLNSIPSASQEILIKPLSLSPELKPSSSLSEKSLKQAVGLGRTWSTLFQYGIDNEQFLPLGKIKSVSALDLAEKLGSSNIIYPMKVWTSDSLVSQDLKQHSFEEADSSNCILGKTVNSSYIIEGPSAAVGSGFSANLVACDAKSQGALPVMSNAPLIAVGQKTLLKADTGQGEIPRPLGARSSFTIHTIMQNDSYFVEGLQGKAESDICTLDDDTECCSVDENAVVCSKRQEICDQGDLTGECVELAGLENLLDDLEICDSSLQWQSTVRLPSKEDSSFEDSVCPSNTDINESFSSVLPPFVPHEPTGDLEYHSSNLRMLRVSPDTVSRTVRHLTGDTSKGGIAEIPQSTFKPGITTFPEDSDTVSPLSLSPEDFPQLAGRSPQVKNIGEYTDTVNQQTLTDSRLTEETLKISAIPGLADQKTGIAAVSSSSYSQRGKPNIFYPQALPDSHLTEEALKVGAVPGLGDQKTGVSTVPPSSYSLGEKHSIFYPQALPDSHQTEESRNVSVLPGLADQKTGKPIVPASSYSVGEEPGIFYHQVLPDSQPPEEALKVLASPRPVDQKSGLPTPSSTYSYGEKPHIFYQQTLPDTHPSEQTLKVSAAPGLAEQKTGVPAVTSASYPHKEKPSIFYQPELPNRRLIQEAHQVSAAPVLVEQKAGISIVPSTSYSHREKPRVVYQQELPESHLIQEVQQVSAAPGLAEQKTGIPTVPSTSYSHREKPSIVYQQELSDSQLIEQSQKVSSVPGLAEQKTGIPTVPSTSYSHREKSSIFYQQELPDSHLTQEVQQVSTAAGPLEQKTGIPTVPSTSYSHREKPHIFYQQELPESHLTEQAHKVSSVPGLAEQKTGISTVASTSYSHREKPSILYQQELPDIHVIHEVPEVSSVPGLAEQKARIPVIPSTTYSHREKPSILYQQELPDSHLTEQVQKASAAPGPAEQKTGIPIITSASYSYREKPIIFYQQDLPDSHLTKEAQKVPTVSGLAHQKSGIPIVPPAFYSHGGKTSLFYQQELPDSHLSDQTQKISAIPGPVDQNTGIQTAPSSSYSYREKPIAFYQQELPGRLLTEEVLKVSALPRTTDQNTGIITGSSQSYLFGEKPSGLFYQHVLPDGSLTEEALKVSPASRPSDQKTGVLLLPASSYSHREKPGIFYPQALPSSHLSEETLKDSAVLGPADQKTGTSEPSGSYSHREKSSIFYQQELPDSHITGEALKISGVSGTGDQKTGIPIVTSPSYSQREKPIVFYQQVLPDTHLTKEALNVSNAPAQADQKTGIPIVTSPSFSYNEKPIIFYQQALPDSQLTVEALKVSDVPGPSDQKTGIPTVPPSSYSYREKPIISYQQESPDLTQVALKVFEVPGPADQKIGIPPVTSASYSYGEKPIISYQQELPDANENALRGLGVPRQADQTVGVRIVPPASYSHRESPIFSYQQELPDLTEEALKVFALPGPADQNAEIPIGPSSSYSHKERLKTSPDDQKTELPSTPSGSYSHREKPKTSTIIGPADQKTPLLTGFPNSYSQRVKPSIFFQQQLGDRHQSGDILKISSVAEPTDVNSQISIPLSASYSHSEKSSVFYPKELPDKHLREDSLKVSTVPGPADKKTVLPAVPPSSFSHREKPAILYHQDFPERHLTEDNLKFSSSLEQADQNNGLSTVPPGTYSHSEKHKPVSHHVQRLTDNLDSSHTSVISNNMPLNSQADGRVVINKPESSGFEDVGSEEIRDTENSSRTLKEIQTLLMEAENIALRRYNVPAPLVPFRDVSDISFIQSKKMVCFKEPLTTDESNDDLSQRQPFTEESSSNKCIQKDISTQTNLKCQRGIENWEFISSTTVRSPLQEAEGKARVAFDETFKQYKAARSVMRSEPEEYSRTIGNKIVIPMMTIIKSDSSSDASSCSWDSNSLESVSDVLLNFFPYSSPKTSMTDSREEEGVLESDDGGGSSVDSLAAHVKNLLKCESSLNHAKQILKNAEEEESRVRARAWNLKFNMAHDYGYSISELNEDDRRKVEEIKAKLFGQGRTTDLSKDLQSPRGIGYKPEAVCSHIIIESHEKGCFRTLTAERPRLDSHPCVFRSAEPSEIVRGQRSPSSWRTRHINLSKSLDQNNSQFKVWNSLQLQSHSPFQNFISEDLEISKGLRMPFHEKLDPWLSELVEPACMPPEEMDCHSSSQMLPPEPMKKFTTSITFSSHRHSKCFSDSSFLKVGVTEGSQCSGASVGVVNSHFTEEQNPPRDLKQRTSSPSSLKIISQSPDKAVTILAENSSQSQKLSVEHSYQEEKPLEKSDFKSSHPKPSASANDSNFKEVHFSDNHTLISMGRPNSTLEVKEKNVTITADLPSHIFLEQEVFEQSKAPHADHHVRKHHSPPPQRQDYVAPNLPCRIFLEKRELFKQSKAPHVDQLRENHSPLPQSQDYIASDLPSSIFLEQRQLFEQSKAPNVDHHLRKLHSPLPQSQDSVVEKNNEHKPKLHISDVIDVEAKFSDVVSPSVPNQCTVVTSASTPPSNRKALSCIRITLCPKTPSKLDSGNLDKRFHSLDPATKTRMNSEFNSDLQTISSRSLEPTSKLLISKPVAQNQESLGFLGPKSSSDFQVVQSPLPDSNVITQDLKTIPYQNSQIVTSRQTQVNSSDLEEYSNPEGTPVSADRSPEEIKSPFSPFSGKLSSDAVTQITTESPGKATFSSEIFVNAEDRGHEIPELNTQKSGNIPVKFASSSSVQQITVPHGTDGQPLLLPYKPSGSTKMYYVPQLTQIPSSLDSKSDTTIESSHSGSNDAIAPDFPAQVLGTRDDDLADTVNIKHKEGIYSKRAVTKASLSMGKKPFQKDNADAHVQVLITGDEDLSDKNQEKEIYTKKAVTKIAGSEEKESLEKDTTGSSTAAASQHSTQDTKTDSLPDTKAIKQKEEVHSKRKVPKEAWSEEKKALQIDIAESRCHSEFENTTHSVFRSAKFYFHHPVHLSSDQDFCHESLGRSVFMRHSWKDFFQHHPDKQREYTCLPSPCQHMEKTKTDYTRIESLSINVNLENKELKRATQSQARDFPKSDKQINDLKRDPKATPELTSEHTVSLNELWNRYQERQKQQKPEVSAKKELSLVERLDRLAKLLQHPITHSLQPSESTQDDSRGEQDAKEWSDKQQQQKNKLQKKKRYKSLEKCHKNTGDLKKNKILSAHQAGRPNQIKIEQFKFDKYILRKHPGFHYINNTSSDSRHSEDSELLTDTTTNILSTTTSPVESDILTQTDKEMTLHERSSSISTIDTARLIHAFGHERVCLSPRRIKLYSSITDHQRRYLEKRSKKNKKALNTGYPQITSEHTRRKHIQVTDHVSSDSVSSSTSSFWSSNSTLCNKQNTHMLNKGVQAGNLEIVSGVRKNTRDVGMTFPTPSSSEARVEEDSDVTSWSEEKIEEKRLLTSYLGDKKLKKNKKTCCEGVSWFVPVENMKSGPKKENMPKLHGPGVSWFAPITNTKPWREPLREQNWQGQHMDSHSSLAGPGKEPLKPFVRATLQESLQLHRPDFISRSGERIKRLKLIVQERKLQNMLQSEREALFNTVQEWQGYRDPVHLLRKRGFLAAQKKRPVGKKEMIQRSKRIYEQLPEVQKKREEEKRRSEYKSYRLRAQLYKKKVTNQLLGRKVPWD", "length": 4331, "header": "tr|E1B958-1|E1B958_BOVIN Isoform 1 of ALMS1 centrosome and basal body associated protein OS=Bos taurus OX=9913 GN=ALMS1 PE=4 SV=3 CANONICAL=E1B958-1" }, "locus": { "chromosome": "11", "start_pos": 11079798, "end_pos": 10889463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047267.5", "url": "https://www.ensembl.org/id/ENSBTAT00000047267.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044487.4", "url": "https://www.ensembl.org/id/ENSBTAP00000044487.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1286, "start_aa": "Thr", "end_pos": 1286, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1286", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4078, "start_aa": "Thr", "end_pos": 4078, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4078", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 692, "start_aa": "Thr", "end_pos": 692, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr692", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:533055", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533055", "resource": "KEGG Pathway" }, { "id": "R-BTA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-BTA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-BTA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-BTA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-BTA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-BTA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-BTA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AH92-1", "protein_name": "ALMS1 centrosome and basal body associated protein", "gene_name": "ALMS1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPEDLPWPGELEEEEEAEEAENLDEDEVVMVEEMEEEEGRDLDADLNYESQRRESTDDEDDEEAKAWLQAHPSGALPLPPLPRYRYSEGELTSPKVIPLTCHVWQQPSYQDNNETQVSDMIVVSLEEKAQWASGDDQRTESWHCLPQEMDSSHTLDTTQTRFNVREKGTEVTNFPSLEEGILTKSENQVKEPSRDLLCSPLLVIQDSFASPDLPLLTCLTKDQEFGPDSLFHQSELDFARLRGIPGKSEDTEWFSRPSEVSEALFQAASEVASDLVSFSVSQHPLTGSEAVESQRSLLTPEQRTKEETVASDTLDELKTHKNSDSYDALCSYMSWKTQEVIQEPGTNLADVSAASDTSDEYITPKGSDSFDASCSYAQFWKQEALQQSEKYLTRKDHDSYSDSSDLIDKNKIPKASDSFSAPFSYMPWSKQEASHHPEIGLISKDHVSFLHEVTPPFNNKMSHSFLHCFLERGGRGVPLTPDSHSKSVYLRAPTESEVKQQMDSLEGYERDEDDLGKGVSQCFELKENRNTLMFSGMHPSSSEIQYIENVFPDNSAKVSEGHTLCRGHDSSMIEASVGPLQTSKSNSDETAEQLYFQEEKDQKATSAFGGKNVDVTENIAFQAVIASIEPSKKESTVNEIQTDISKSSTNDSQKSEQKNPDLFLLNYDENSFFDKLNHSCYQSTPGVFESVASKPSLYKKDNGDSSLYWHPDLKSLPSAPQEIFIKPVSLIPELKSSSLSEKSVRQAVDLGKTQSALFQDDTDSELFLPIGKIKSVSALDLAEKLGSSNIIYPMKVWTSDSLVLQELKPQTFEEVADSSNYILGKNVNSSNIIEGPSAAVGGSFSANLVACDAKSQGSLPVISDAKAAVGQETLLKANIGPGEIPWPMGAKSSFTIHTVMQNDSYFVEGLQGKAESDICTLDDAAECCSLDENAVVCSKRVAELQREICGQGDLTSECTELAGLKNLLDDLEICDSSPHWQSSVELPSKEESSCEVPVGPSDTDINQSFSSALPPFVPHESTRELEYHSADLRMLRVSPDTVPGTLKHLTGDTSKGGVLEIPQSTFKSGITTTPEDSDTGSHLSLSSEDFPELALRSPQVKNIGQYTDTLNQQTLTDKHLTEETLKISTIPGLVDQKTGIPPSSYLLGEKHSIFYPQALPGGHLPEEALKASILPVPTDQKTGIPTVPAGSYSPEEKTGIFYQQGLPSSHLPEEALKVSVLPGPADQKTGLPTVSSTSYLHGEKPHIFYQQTLPESHLTEQAVKVSAAPGPSEQKTGIPTIPSTSYAHRQKPSVLYQQELPDSHLTEQAQKISALPGLAEQKSGISAVPSASYPHREKPSILYQQELLNSHLIQQVQQVSAVPLPPEQKTGFPAIPSTSYSHGEEPSVLYQQELPDSHLIQQIQQVSAAPGLAEQKTGIPRVPSSSYSPREKSSILYQQELPDSHLIQQVHQVSAAPGSPEQKTGIPTIPSTSYSHREKPHNFYQQELPDSHPTEQAQKVSAAPGLAEQKTEISTVPSSSYSYREKPSILYQQELPGSHLTEQAQKVSAAPGLAEQKTGISIVPSASYPYREKPSILYQQELPDSHLTEQTQQVSAAPGLTEQKTEILTLPSTSYSHQKTARTSYSHIEKPSIFYQQDLPNSHLTKAHKVPADPELAHQKSGIPIAPPAFYSQRGKTSLFHQQELPDSHLSDQTQKISAISGSVDQNTGIQTVPSSSYSHREKPIIFYQQELPDSHLTEEALKVSAVPRTVDLNTGIPTRSSRSYSFGEKPGSIFYQQVLPDGHLTEEALKVSSASRPSDQKTGILSVPASFYSYRERPSIFSPQALPGSHPSEEALKDSASPGLADQKTRTLESSSSDLHREKSSIFYQQELPDSHLAGETLKVSGVSGPGDQKTGIPIVSSASYLHKEKPIILYPQALPDRHLIEEALNVSTDPGPADQKTGIPVVTSPSYSHKEKPIIFYQQALSDSQLTVEALKVSGAPRSAAQKTGIPIVPSSSYSYRERPIISYQQELPDLTQVALKILEVPGPADQNIGITAVPSPPYSHGEKPIISYQKELPEPNEDSLTHMGVPGQADQTTGIQTVPPASYSRRESPLFSYQKELPDVTEETLKVSAVPGLVDQKIGLQTIPPGPHSYGEKANVFYQQELPDLTEEALKIFALPGPADQNNEIPTGPSGSYSHKEKLKILPDDQKTELPLAPPSSYSHREKPKTSTVIGPDDQKTPLLTGVPNSYSQRVKSSIFYEQQLPDRHQSGDILKISPIAEPTDVNSQLPIPLSSSYSHREKSNIFYPEELPDKHLTGDALKVSTIPGPADQKTVLPAIPSSSFSYREKPVVFYQQDLPERRLTEENLKFSSSLGQADQITGLSTVPSGTYLHSEKHKLVSDHVQRLIDKLDSPNSSVISNNMPLNSRADGGVVVSQTESLGFEDVGSEEVRGTENSSRTLKEIQTLLMEAENIALRRCNFPVPVPLVPFRDVSDISFIKSKKMVCFKEPPTTDESNGDLSQRQPFAEESPSNKCIQKDISTQTNLQCQRGTENWEFITSTTVRNPLQEAESKARVALDETLRQCKAANSVMRSEPEAYSGSFGNKIVIPMMTIIKSDSSSDASSCSWDSNSLESVSDVLLNFFPCSTPKTSMTDSRDEEGLLESDDGGGSSVDSLAAHVKNLLQCESSLNHAKQILRNAEEEESRVRARAWNLKFNMAHECGYSISELNEDDRRKVEEIKAKLFGHGRTTDLSKGLQSPRGIGCHPEAVCSHIIIESHEKGCFRTLTAERPQLDSRPYVFRSADSSEMIRGQRSPSSWRNRHINFSKSLDQSASHFRVWNSLQLQSPSPFQNFIADDLKISKGLRMPFREKLDPWLSELEPACVPPEEMDCHSSSQMLPPEPMKKFTTSITFSSHRHSKCFSDSSFLKVGVTEGSQCTGASLGVFNSHFTKEQNLPRDLKQENSFPSSFKTISQSPDKAMTLLAENSRQGQKLSVEHSHQEEKLIERSDFKGSHSKPGTSANDSNFKEVHFADNHTLISMGRPSSTLGIKEKNVTITPDLPSHIFLEQELSEQSKAPHADHHVRKHHSPPPQHQDYVAPNLPCRIFLEERELFKQSKAPHVDHQMRENHSPLPPSQDFIAPDLPSSIFLEQRQLLEQSKTPDVDHHMRKHHSPLPQGQDYVVERNNQHKPELHISDMINVEAKFSDVVSPSAPVVTSASTPPSNRKALSCIRITLCPKTPSKVDSGTLDKRIHSLDPASKTRMNSEFNSDLQTVSPRSLEPTSKLLTSKPIAQDQASLGFLGPKSSPDLQVVQSPLPDSNITQDLKIIPFQNSQIVTSRQTQVNISDLEEYFNPEGTPVSADRSPEEIKTLFSPFSGKLSSDAVTQITTESPGKAVFSSEIFVSAKDREHEIPELTTQKVGKGLVKFASSSSVQQITVPQSTDVQPLLLPYKPSGSTKMYYVPQLSQIPSSLDSKSDTTIESSHSGSNDAIAPDFPAQVLGTRDDDLTDAVNIKHKEGIYSKRAVTKASLFVGKKPFQKDNADAQVQVFITGNEDPSGENQKKESSSKRAVPEAAQSEEKEPLLKDTADSSTAAASGYSTQPQDSKIDNIPATKAIKQKEEMHSKKTVPKEAWPEEKKSLQIDIAESRCHSEFENTTHSVFRSAKFYFHHPVHLPNDQDFCHESLGRSVFMRHSWKDFFQHHPDKEREQTFLPPPYQNMEKTKTDYTRIESLSINVNLENKEVKQTPKSQARAYPKCDKQVNDPKSDHKPTPELTTQPTVSLNELWNKYQERQKQQKPPEFGAKEELSLVERLDRLAKLLQHPITHSLQPSESTQDDSRGEQEVQEWSRRQQQQKNKLQKKKRYKSLEKCHKNTSDLKKNKILSTHQPGRSNQIKIEQIKFDKYILRKQPGVHYINNTSSDSRHSEESELLTDTPILSTTTSPVESDILAQTDKEVTLHDGSSSISTIDTARLIHAFGHERVCLSPRRIKLYSSITDHQRRYLEKQSKKNKKALNTGYPQITSEHTRRKHIQVTDCISSDSVSSSTSSFWSSSSTLCSMQNVHMLNKGIQAGTLEIVNGVRKHTRDVGMTFPTPSSSEARVEEDSDVTSLSEEKIEEKRILTSYFGDTKLRKNKQSCCEGVSWFVPVENVKSGPKKENLPKFHGPGISWFAPITNTKPWREPLREQNWQEQHIFSHGSLAGPGRHPLKPFVRATLQESLQLHRPDFISRSGERIKRLKLIVQERKLQNVLQSEREALFNTVQEWQGCRNPMHQLPKRGFLAAQKKRPVGKKEMIQRSKRIYEQLPEVQKKREEEKRRSEYKSYRLRAQLYKKKVTNQLLGRKVPWD", "length": 4332 }, "evidence": [ { "id": "E1B958", "url": "https://omabrowser.org/oma/group/E1B958/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6G4M9-1", "protein_name": "ALMS1, centrosome and basal body associated protein", "gene_name": "Alms1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPEDLPWPDELEEEEEEEEEEGKEEAENASAAATEEARTSEETGRLEEEELEGAGPEVDLDFNSESQLQESTDEEEDELAKAWLQAHPDRPGQGFSLTPPPTPPPSSRHQYRPVEHWGKREVRGRAVAWIGAVVIPLTYRAWQQTSYQDNARAQFSNSSTLLLEPEFQWDPEEVQRTESWHHLPQERDSFQTLNISQTGIDRVEGAEVKDLPSQEGGESVQAQCPVKEPKLDLLCSPLLVIQDDFAAPDLPLLTCMTQDQEFEPDSLFQQSELEFAPLRGIPDKSEDIEWLARPSEVSEALIQATSESSSDLVNSCFSISQHPLTGSTIFGSQRSLSLFEQENNRETVPCNAPDDLKSPDNSYHYDAQYSYMSWLTEKDTQQPEGSLADKDQASSTTISDISDESITVKRSSALGISCSYSQYRKQEALKQTEASLASKDHASFSRQITSLPNKMSRSFLRCMLKRGEGTPLTSDNPPENVCLRTPAEDEMSQKNDSLEGYEGNEDLQKELSQYFKQKETRNTWASSRVHAKYPEIKSLGTVAIPESQKRVAESYILCRGLDISKLDTSGCPLPTVKSNFNETSEQLCFQEERNQKAATTFDEKNVDATGNVAFEAIIASIESSNQEGSVSETQTDSSQLLADDSEEKKTLKPDLSPFSCKDEISFIDKLKYQYQSTPAVFEPADSKPLLCKEDDAGSLYHYPDLKHPINVPQSMLEGLQGKAKSDVLILFGDAKYASIYENAGAHSERITELQREVDCSNLSITQAFPSSLPSFVPQEPTIESEYHSSNLRMLRVSPDTLLTTLTQTTGSVDQKIGAAAISSPYSHGVQPGSFPQEELPDRHLTEEIRKVSPAPRPAGQKPEMPTVPSSSYSKGIKSVFYRYPMSYSPQGKEPPNVSSVSGSAENALPLTVTSVSQPQRETAKAFYQQTLSDSLLTAETLPVSVIPESGDQKTHLLSGFSLSYSHRGEDLPEDVVKVSTDSGSVDKKADIPTVSSSTYQHKTKPGIIYYQEFPDSHVPIGTRKVVSQSGAAGQKTDLSAVPSTSSSQAEKPVPPSLLTLLGSHLPEDVFKASYVCKSSEEPSGITALTSVSYSYKGRPNISHQEKFPDSYLIEEAQKILGSTVTVDQKTVTAKEKPSVFYQQALPEGGLSAEDLQVDQNIAIPMVTSASFSQREKPQVFYQEALSGGHLPGEPPGPPDQNTEAPTISPSSYFPGEESIIFYQAGFPGNTPSVVPFKVSRISELAEQKTNITTGPSGSYSVGEKSIIFYHQALPDGHLSKEASPAPADLKTGEPPVYSASCSVEVKPIIFYQQPLSDSPLTKGHNVSVVPGPTDQKTGIPAVPSTSQSYIERRSVSYQQEFPNVSEKALKVLGGVRSTEQKTEIPVVSSALLHTEVPTISSQEDLPNLTEEALQILGVAEEVPSVPSRDKTRLISYQKKLPDGTEVSLKSVGFGSTDQKTGAHIVSSSRREKSSGFHQQELPNTCGDALGTFHPEPVAQKVGKPTEPSNIQGKASALSPQQLPASHLTGEALKVSDGSACVAQMPEAPAGPSIFYFHKERFSNYQKASPDCDLTENSLKSSTVPGLSDQKKRPPVSSGSCSHKEKHKISAADLLDAQAAELPTVIQRSCLHREKLAISTVIKPDDPKIPLPTTCHASCAQKVKPVIFVQKQLSGRDQSEDIPKISTVSEPTVANTGAPVLLSSSYPYREKSDFSSPKELPDRHPAKVDMQASSSLGQADQISRLPTVPPGTYSHSEKYQLISEHVQELIDNLNSSESCLNADIMMPSNSQIDDGVIICKPESSRFANVGCEEIQDIDHGSKTLKEIQTLLMEAENMALKRCNFSVPLVPFRDVSDVSFVQSKKVVCFKETPTSDVCIQKDSFAEEVPHTKYVQKDIGTQTNLKYQRNVRNWEFISSATFRSPLHEANGTARVAFDENFRQYRATRSVMRSEPEDCSTGIGDKIIIPMMTIIKSDSSSDVSDGCCSWDNNLPESLESVSDVFLNFFPYTSPKTSITDSREEEGLSESEDGYGSADSLAAHVKYLLQCESSLNQAKQILKNAEEEEYRVRAQAWNLKFNLGRDYGYPVSELNEDDRRKVEEIKAKLFGHGRTTHVSEVLQSPRGIGCLPEAVCGHIIIESHEKGCYRTLTAEQPRPDSCHCVFRSVDPSDLIRGHRSPSSWRGRHINLSRSIDQSNPHFKIGNSFQLQSHPPFEKLVPDDIKISKGVGMPFHEHMDPQPSELIEPTCVPAKEMDFSSSSEILPSEPKKQFTTSITFSSHQHSKCISDSSGFKVDVTAGSQCTGPSLGVFKPHIPEEQISPRDLKQKISSPSSLQRHSYTPVTILVDSSRQRQKLPVDFEHSNQKGKLLQRSAFNFSHSEPSVSTNVSFKGVQFSGNDTIVRQDKLISTVEVKEKNVTLTPDLPSCIFLEQGEESHTPHTDLHMRKCPSPSGLDIASCIFLEQHKFFEQSQGQHVDDHEMREDYSLFPKCQGYIAADPSDFPDQQQCKPPGVDGHVRKQHYPLSPVQDCEVEEVQCIPQSYFSNMVNVEAKVSDMVSPDAPDHFTAASTPPSSRKALSCVRITLCPKTPSKLDSGTLDERFHSLDPASKTRINSEFNSDLRIISSRSLEPTSKLLTCKPVAQDQESLVFLGPKSPLDLQVAESSLPDSKTISQDLKTTPPQNSQIVTSRQTQVNISDLEEYSKPEGTPVPADGSQEQNKAPFTTSSGMLSSDAVTQVTTESPEKMTFSSEIFINADDRGQDIPYPTTQNPSRFASSSSGQQITASQGKDAQPVLLPYKPSGSSKMYYVPLLKPVPSYLDSKSDTTVESSHSGSNDAIAPDFPPQVLGTRDDDLSTTVNIKHKEGIYSKRAASKGKQPSQKEAPVQMPVTWDKNVYKENQDEIISRRVVIETAGPEEMPSQEKDLAGSSDITVQDRKTGNLPDAKSIKQKEGSLEIEPECHSEFANTTHSVFRSASFYFHHPVHLPQEQDLCRESSGRNVLTQHPWKDLFHCHSGHSGLPPPGPRSDNTEMECTRVKSLSMDLNLGGHEKIHTIKNQARDTKEDKRPANDPKKDQKVTPELTSQCPMSLNELWNKYQERQKQQKPSGACDNKELSLVERLDRLAKLLQNPITHSLQASESTQDDRRWGRGARGWTGRRQHQQKGKQQRKWSKSLERGHSTGDFRKSKVLSPHEGGKSSQRNIEKIKLDKYILRKQPDFNNVSNTSLDSRPSEESELLLTDSPNLFSSTESPVESDVLTHTGRDMPLNERSSSISTVDTARLIQAFGHDRLYLSPRQIKLYSSVTNQRRKHLEKPCKHKRKALNTACPQMTSEHTRRRHVQVANRIMSSDSVSSAGSCLSLDSTLSNEENVHMLNKGVQAGNLEIVTGAKKYTQDVGVTFPTPSSSEARLEEDSDMTSWSEEKAKEKKFLSNYLRGKNLRKNKPNPCEGVSWFVPVENRKSESKKENLPKIYRPAISWFEPVTQTKPWREPLREQNWQAQCMNSRGSLGGPGRDSGQSFLQPFVRATLQESLQLHRPDFISRSGERIKRLKLLVQERKLQNLFQNEREALFNTARPLPRRVLLAVQKNKPIGKTEMIRRTRRFYEQLPEVKKKREEEKRKSEYTSYRLRAQHYKMKVTNHLLGRKVPWD", "length": 3645 }, "evidence": [ { "id": "E1B958", "url": "https://omabrowser.org/oma/group/E1B958/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K4E0-1", "protein_name": "Centrosome-associated protein ALMS1", "gene_name": "Alms1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPEDLPWPDELEEEEEEEEEEGEEEEGKKEVENASAAATEEALTSEESGRLEEFEEAGPDLDFNYESQRQESSDEEEDELAKAWLQAHPDRPGSAFSLPPPTPPPPPPPLSPRLRYTPVEHLGKTEVVPLTCRVWQQSSYQDNSRAQFSNSSTMLLETGVRWGSEEDQRTESWHCLPQERDSSQTLAMSQTEIGRVEGTEVPDLPSQEGGLPAQSQCPGKKPKLNVLCSPLLVIQDNFAAPDLPLLTCLIQDQEEVEPDSLFQQSELEFAPLRGIPDKSEDSEWLARPSEVSEALIQATSETSSDLANSCFSISQHPLTEGLQGKAESGVLTRCGDAKYSSLYENLGAQSERIAVLQREVGCSNLGISQASPSSLPSFVPQEPTSEPEYHSSNLRMLRVSPDTLLTTHTHSAGSADQKIGAAVVSSAYSQEIKPGSFHQEELPDRHLNEEIRKVSPALRTAGQKPEMLPVQSSSYSKGMKSIFYQHPVSHGHQGKEPLSVSAVCGSAGNKAFHQLSTLSDSLLTEETWPVSVIPGLGNQKTPLPSEFSLSYSHRGKNLPEDVVKVSTDSGSAHKKADILTASSRTYQHKMKPANIYHQELPDSRVPIGTRKVAFESGPAGQKSGVSHPYGEMPSVFYQQGLPDRHSAKSPTKTFIPGPADQKTDLSPVPPTSSSHAEKPVSPYQLTLPGSHLPEDVFKASSVCKSSDELSGITALTSASYSYKGRPNSSYQQKFPDSHLNEEAQKILGTTGTVDQKTVTPTMSSSFLQKEKPSIFYQQTLPDGGLSEEDLQVSAVPWPADQNIAIPTVTSAAFSQREKPRIFYQQTLSVDRLPGEPLNVLGTSGPPDQNTGAPTVTPSSYFPGEESIIFYQAGFPGNTLSAMSFKVPRISGSTEQTNVTTGSSSSYSVGEKSIIFYHQALPDGRLPQEASPAPADLNTGEPPMYLASCSVGVKPIIFYQQPMSDSQRTKGHKESDVPGPTDQKTGIATVHSTSQSYIGRRTVSYQKEFPDLSEKALKVLGDVGSTEQKTQIPVVSSALLHKEGPSAYQEDLPDLTEEPLQILGVSEEVSSSSYQRKLPDHIEVFLKSVGSGSADRKTGAQIVSSSREKSSGFHQQELPNTGGDAVDAFHPEPVVQEVRKVQTPGAPAGPSSSHFHKEKLSDYQKASPHRDLTESSLKASTVPGLSDQKKKPAVSSGFCLHKEKHEISASALLNCQTAELLTVTQRSCLHREDPAISTVIKPDDQKIPLPTTFHGSSDQKVKPVIFVQKQLRDRDQSEDIPKISTVSEPTVVNTVLPVLLPGSYSHREKSDSFYPQELPDGHLTEVDLKVSSGLGQADQISGLPTGIPGTYSHSEKHQLISEHVQELMDNLNSSESSCLSVDSMPLNSQIDDGVIICKPESLGFANAGCEEMQNIDRGSKTLKEIQTLLMEAENMALKRCNFSVPLVPFRDVNDVSFIRSKKVVCFKESSTTDVCTQRESFVEEVPHIEYVQKDIGTQTNLKYQRGVGNWEFISSATFRSPLQEAEGTARMAYDETFRQYKAARSVMRSEPEGCSTGIGNKMIIPMMTIIKSDSSSDVSDGCCSWDNNLPESLESVSDVFLNFFPYTSPKTSITDSREEEWLSESEDGYGSTDSLAAHVKYLLQCETSLNQAKQILKNAEEEEYRVRTQAWNLKFNLGRDRGYSISELNEDDRRKVEEIKAKLFGHGRATHMSEGLRSPQGIGCLPEAVCSRIIIESHEKGCFRTLTAEQPRPDSCHCAFRSVEPSDLIRGHRSPSSWRGRHINLSRSIEQSNPCFKVGSSFQLQSHPPFQKLLPDDIKISKGVGMPVHAYMDPQPSELVEPTCVPAKEMDFPSSSQILPPEPKKQFTTAITFSSHEHSECISDSSGCKVGVTADSQCSGPSLGVFKPHIPEEQISPRDLKQKTSFQSSLERHGSTPVTILADGSRQRQKLPVDFEHSHQKEKLLQRLGFKVSHSEPNVSTNVSNFKGVQFSGKDTIVSQDKLTSTVEVKEKNVTVTPDLPSCIFLEQPELFEESHTPHTDLQMRKYPSPSCPEIASRIFLEQPKLSEQSKAPHVDREIREDHSFFPKCQDYIVADPSPDFPDQQQCKPPDVVGHTRKQNSLLSEGQDYELEEVQHIPQSYFSNMVNVEAKVSDAISQSAPDHCTAASTPPSNRKALSCVRITLCPKTSSKLDSGTLGERFHSLDPASKTRINSEFNSDLRIISSRSLEPTSKLLTCKPVAQDQESLVFLGPKSPLDLQVAQSSLPDSKTIFQDLKTKPPQNSQIVTSRQTQVNISHLEGYSKPEGTPVSADGSQEQSKVSFTTSFGKLSSDAITQITTESPEKTTFSSEIFIHADDRGQGILDPMAQKPSRFASSSSVQQIPASHGKDAQPVLLPYKPSGSSKMYYVPLLKRVPSYLDSKSDTTVESSHSGSNDAIAPDFPPQMLGTRDDDLSNTVNIKHKEGIYSKRAATKGKNPSQKGDAAAPVQMPITWDENVLDENQEEVISRGVVIKMAGPEEMSSLEKDLAGPSDITVQDRKTENLPDTKSIKQKEGSLEIESECHSAFENTAHSVFRSAKFYFHHPVHLPHEQDFCHESLGRSVFMQHSWKDFFHHHSGHSCLPPPGPSSDKLDKTKMDYTRIKSLSINLNLGEHEKIHTIKNQARDPKGKRQANEQKKDQKVTPELTTECPVSLNELWNRYQERQKQQNPSGACDTKELSLVERLDRLAKLLQNPITHSLRASESAQDDSRGGHRAREWTGRRQQKQKGKQHRKWSKSLERGQSTGDFRKSKVFSPHQGGKSSQFKIEQIKLDKYILRKEPGFNNVSNTSLDSRPSEESVSLTDSPNIFSSTDSPVDSDVLTPTDRDMPLNERSSSISTIDTVRLIQAFGQDRLSLSPRRIKLYSTVTSQRRRYLEQPCKHNRKALNTACPQMTSEHSRRRHIQVANHMTSSDSVSSPGSLLSLDSALSNEETVRMVSKGVQAGNLEIVAGVKKYTQDVGVTFPTPSSSEARLEEDSDVTSSSEEKAKEKKFLSNYLQTKNLRKNKPNPCAGVSWFVPVESGQSGSKKENLPKIYRPVISWFEPVTKTKPWREPLREQNWQAQCMNSRGSLGGPGRDSGQVSLRPFVRATLQESLQLHRPDFISHSGERIKRLKLLVQERKLQSLFQSEREALFHSARPLPRRVLLAVQKNKPIGKKEMIQRTRRIYEQLPEVKKKREEEKRKSEYKSYWLRAQHYKMKVTNHLLGRKVPWD", "length": 3251 }, "evidence": [ { "id": "E1B958", "url": "https://omabrowser.org/oma/group/E1B958/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TCU4-1", "protein_name": "Centrosome-associated protein ALMS1", "gene_name": "ALMS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPEDLPWPGELEEEEEEEEEEEEEEEEAAAAAAANVDDVVVVEEVEEEAGRELDSDSHYGPQHLESIDDEEDEEAKAWLQAHPGRILPPLSPPQHRYSEGERTSLEKIVPLTCHVWQQIVYQGNSRTQISDTNVVCLETTAQRGSGDDQKTESWHCLPQEMDSSQTLDTSQTRFNVRTEDTEVTDFPSLEEGILTQSENQVKEPNRDLFCSPLLVIQDSFASPDLPLLTCLTQDQEFAPDSLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSRFSVSQHPLIGSTAVGSQCPFLPSEQGNNEETISSVDELKIPKDCDRYDDLCSYMSWKTRKDTQWPENNLADKDQVSVATSFDITDENIATKRSDHFDAARSYGQYWTQEDSSKQAETYLTKGLQGKVESDVITLDGLNENAVVCSERVAELQRKPTRESEYHSSDLRMLRMSPDTVPKAPKHLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSIPAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPELTDVNTGKPVSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPGPAGQKTVLPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQITGLQTVPSGTYSHGENHKLVSEHVQRLIDNLNSSDSSVSSNNVLLNSQADDRVVINKPESAGFRDVGSEEIQDAENSAKTLKEIRTLLMEAENMALKRCNFPAPLARFRDISDISFIQSKKVVCFKEPSSTGVSNGDLLHRQPFTEESPSSRCIQKDIGTQTNLKCRRGIENWEFISSTTVRSPLQEAESKVSMALEETLRQYQAAKSVMRSEPEGCSGTIGNKIIIPMMTVIKSDSSSDASDGNGSCSWDSNLPESLESVSDVLLNFFPYVSPKTSITDSREEEGVSESEDGGGSSVDSLAAHVKNLLQCESSLNHAKEILRNAEEEESRVRAHAWNMKFNLAHDCGYSISELNEDDRRKVEEIKAELFGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTSEHPQLDRHPCAFRSAGPSEMTRGRQNPSSCRAKHVNLSASLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFKISKGLRMPFDEKMDPWLSELVEPAFVPPKEVDFHSSSQMPSPEPMKKFTTSITFSSHRHSKCISNSSVVKVGVTEGSQCTGASVGVFNSHFTEEQNPPRDLKQKTSSPSSFKMHSNSQDKEVTILAEGRRQSQKLPVDFERSFQEEKPLERSDFTGSHSEPSTRANCSNFKEIQISDNHTLISMGRPSSTLGVNRSSSRLGVKEKNVTITPDLPSCIFLEQRELFEQSKAPRADDHVRKHHSPSPQHQDYVAPDLPSCIFLEQRELFEQCKAPYVDHQMRENHSPLPQGQDSIASDLPSPISLEQCQSKAPGVDDQMNKHHFPLPQGQDCVVEKNNQHKPKSHISNINVEAKFNTVVSQSAPNHCTLAASASTPPSNRKALSCVHITLCPKTSSKLDSGTLDERFHSLDAASKARMNSEFNFDLHTVSSRSLEPTSKLLTSKPVAQDQESLGFLGPKSSLDFQVVQPSLPDSNTITQDLKTIPSQNSQIVTSRQIQVNISDFEGHSNPEGTPVFADRLPEKMKTPLSAFSEKLSSDAVTQITTESPEKTLFSSEIFINAEDRGHEIIEPGNQKLRKAPVKFASSSSVQQVTFSRGTDGQPLLLPYKPSGSTKMYYVPQLRQIPPSPDSKSDTTVESSHSGSNDAIAPDFPAQVLGTRDDDLSATVNIKHKEGIYSKRVVTKASLPVGEKPLQNENADASVQVLITGDENLSDKKQQEIHSTRAVTEAAQAKEKESLQKDTADSSAAAAAEHSAQVGDPEMKNLPDTKAITQKEEIHRKKTVPEEAWPNNKESLQINIEESECHSEFENTTRSVFRSAKFYIHHPVHLPSDQDICHESLGKSVFMRHSWKDFFQHHPDKHREHMCLPLPYQNMDKTKTDYTRIKSLSINVNLGNKEVMDTTKSQVRDYPKHNGQISDPQRDQKVTPEQTTQHTVSLNELWNKYRERQRQQRQPELGDRKELSLVDRLDRLAKILQNPITHSLQVSESTHDDSRGERSVKEWSGRQQQRNKLQKKKRFKSLEKSHKNTGELKKSKVLSHHRAGRSNQIKIEQIKFDKYILSKQPGFNYISNTSSDCRPSEESELLTDTTTNILSGTTSTVESDILTQTDREVALHERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKRSKHSKKVLNTGHPLVTSEHTRRRHIQVANHVISSDSISSSASSFLSSNSTFCNKQNVHMLNKGIQAGNLEIVNGAKKHTRDVGITFPTPSSSEAKLEENSDVTSWSEEKREEKMLFTGYPEDRKLKKNKKNSHEGVSWFVPVENVESRSKKENVPNTCGPGISWFEPITKTRPWREPLREQNCQGQHLDGRGYLAGPGREAGRDLLRPFVRATLQESLQFHRPDFISRSGERIKRLKLIVQERKLQSMLQTERDALFNIDRERQGHQNRMCPLPKRVFLAIQKNKPISKKEMIQRSKRIYEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQLLGRKVPWD", "length": 4168 }, "evidence": [ { "id": "E1B958", "url": "https://omabrowser.org/oma/group/E1B958/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1B958", "url": "https://www.uniprot.org/uniprotkb/E1B958" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1B958", "url": "https://www.uniprot.org/uniprotkb/E1B958" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1B958", "url": "https://www.uniprot.org/uniprotkb/E1B958" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "E1B958", "url": "https://www.uniprot.org/uniprotkb/E1B958" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of centriole replication", "id": "GO:0046599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046599", "evidence": [ { "database": "UniProtKB", "id": "E1B958", "url": "https://www.uniprot.org/uniprotkb/E1B958" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1009, "end_pos": 1011, "annotation": "n_glycosylation_sequon" }, { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1223, "end_pos": 1225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1974, "end_pos": 1976, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2438, "end_pos": 2440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2805, "end_pos": 2807, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2813, "end_pos": 2815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2968, "end_pos": 2970, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3004, "end_pos": 3006, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3016, "end_pos": 3018, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3026, "end_pos": 3028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3035, "end_pos": 3037, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3109, "end_pos": 3111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3330, "end_pos": 3332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3639, "end_pos": 3641, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3899, "end_pos": 3901, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3900, "end_pos": 3902, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4038, "end_pos": 4040, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 653, "end_pos": 655, "annotation": "n_glycosylation_sequon" }, { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" }, { "start_pos": 835, "end_pos": 837, "annotation": "n_glycosylation_sequon" }, { "start_pos": 910, "end_pos": 912, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B958", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B958" }, { "id": "PF15309", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15309" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ALMS motif", "eco_id": "ECO_0000259", "start_pos": 4195, "end_pos": 4327, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 692, 1286, 4078 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1009, "end_pos": 1011 }, { "start_pos": 113, "end_pos": 115 }, { "start_pos": 1223, "end_pos": 1225 }, { "start_pos": 1974, "end_pos": 1976 }, { "start_pos": 2438, "end_pos": 2440 }, { "start_pos": 2805, "end_pos": 2807 }, { "start_pos": 2813, "end_pos": 2815 }, { "start_pos": 2968, "end_pos": 2970 }, { "start_pos": 3004, "end_pos": 3006 }, { "start_pos": 3016, "end_pos": 3018 }, { "start_pos": 3026, "end_pos": 3028 }, { "start_pos": 3035, "end_pos": 3037 }, { "start_pos": 3109, "end_pos": 3111 }, { "start_pos": 3330, "end_pos": 3332 }, { "start_pos": 3639, "end_pos": 3641 }, { "start_pos": 3899, "end_pos": 3901 }, { "start_pos": 3900, "end_pos": 3902 }, { "start_pos": 4038, "end_pos": 4040 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 653, "end_pos": 655 }, { "start_pos": 658, "end_pos": 660 }, { "start_pos": 835, "end_pos": 837 }, { "start_pos": 910, "end_pos": 912 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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{ "database": "Ensembl Peptide", "id": "ENSBTAP00000037816.6", "url": "https://www.ensembl.org/id/ENSBTAP00000037816.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1B983", "url": "https://www.uniprot.org/uniprotkb/E1B983" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "E1B983", "url": "https://www.uniprot.org/uniprotkb/E1B983" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "E1B983", "url": "https://www.uniprot.org/uniprotkb/E1B983" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "E1B983", "url": "https://www.uniprot.org/uniprotkb/E1B983" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "E1B983", "url": "https://www.uniprot.org/uniprotkb/E1B983" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B983-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 154, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B983-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B983" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B983", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B983" }, { "id": "PF03939", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03939" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL23 N-terminal", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 66, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1B987-1", "uniprot_ac": "E1B987", "uniprot_id": "E1B987_BOVIN", "mass": { "chemical_mass": 29331.0, "monoisotopic_mass": 29331.0 }, "refseq": { "ac": "NP_001193087", "name": "palmitoyltransferase ZDHHC22", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193087" }, "gene_names": [ { "name": "ZDHHC22", "type": "recommended", "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ] }, { "name": "ZDHHC22", "type": "synonym", "evidence": [ { "id": "NP_001193087", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193087" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987/entry#names_and_taxonomy" } ] }, { "name": "palmitoyltransferase ZDHHC22", "type": "synonym", "evidence": [ { "id": "NP_001193087", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193087" } ] }, { "name": "zinc finger DHHC-type containing 22", "type": "synonym", "evidence": [ { "id": "NP_001193087", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193087" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B987", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZDHHC22", "url": "https://www.uniprot.org/uniprotkb/E1B987", "locus": { "chromosome": "10", "start_pos": 88331088, "end_pos": 88338150, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014384", "url": "https://www.ensembl.org/id/ENSBTAG00000014384" } ] } } ], "crossref": [ { "id": "E1B987", "url": "https://alphafold.ebi.ac.uk/entry/E1B987", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014384", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014384", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613943", "url": "https://www.ncbi.nlm.nih.gov/gene/613943", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613943", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613943", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GQTWCQL", "url": "https://omabrowser.org/oma/group/GQTWCQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B987", "url": "https://www.orthodb.org/?gene=E1B987", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193087", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193087", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1B987", "url": "https://www.uniprot.org/uniprotkb/E1B987", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B987-1", "url": "https://www.uniprot.org/uniprotkb/E1B987-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLALRLLNVVAPAYFLCIALVTLVLQLFLFLPRMREDPTAARLFSPALLHGALFLFLSANALGNYVLVIQNSPDDLDACQGAEARRALCPPPSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVAYISAVLSISFAHPLAFLTLLPTSISQFFSGAVLGSEMFVILMLYLWFAIGLACAGFCCHQLLLILRGQTRHQVRKGVAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGSESCKQRDK", "length": 263, "header": "tr|E1B987-1|E1B987_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC22 PE=3 SV=1 CANONICAL=E1B987-1" }, "isoforms": [ { "isoform_ac": "E1B987-1", "url": "https://www.uniprot.org/uniprotkb/E1B987/entry#E1B987-1", "sequence": { "sequence": "MLALRLLNVVAPAYFLCIALVTLVLQLFLFLPRMREDPTAARLFSPALLHGALFLFLSANALGNYVLVIQNSPDDLDACQGAEARRALCPPPSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVAYISAVLSISFAHPLAFLTLLPTSISQFFSGAVLGSEMFVILMLYLWFAIGLACAGFCCHQLLLILRGQTRHQVRKGVAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGSESCKQRDK", "length": 263, "header": "tr|E1B987-1|E1B987_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC22 PE=3 SV=1 CANONICAL=E1B987-1" }, "locus": { "chromosome": "10", "start_pos": 88338150, "end_pos": 88332391, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019123.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019123.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019123.4", "url": "https://www.ensembl.org/id/ENSBTAP00000019123.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:613943", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613943", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N4B4-1", "protein_name": "Palmitoyltransferase", "gene_name": "Zdhhc22", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLALRLLNVVAPAYFLCISLVTFVLQLFLFLPSMREDPTATPLFSPALLHGALFLFLSANALGNYVLVIQNSPDDLGTCQATSSQRSQCPPPSTHFCRVCSRVTLRHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYISAVLSISFSHPLAFLTLLPTSISQFFSGAVLGSDMFVILMLYLWFAVGLACAGFCCHQLLLILRGQTRYQVRKGVAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGTESSKQQDK", "length": 263 }, "evidence": [ { "id": "E1B987", "url": "https://omabrowser.org/oma/group/E1B987/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XMA1-1", "protein_name": "Palmitoyltransferase", "gene_name": "ZDHHC22", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLVLRLLNVVAPAYFLCISLVTFVLQIFLFIPSMFRDPSTTPLFSPALLHGALFLFLSANALGNYILVIQSSPEELGKGLNLGEGAEMVADWLDGSRSPGSALPSTHYCRLCARVTQRHDHHCFFTGNCIGSRNMRNFIMFCLYTSLACLDSLVAGMAYISASLSMSFANPLAFLTLLPHSISQFFSGALLSSEMFVILMLYLWLGIGLACAGFCCHQLLLILRGQTRYQVRKGMVVRARPWRENLREVFGKRWLLGLLIPMLNVGSDCRRQKVK", "length": 275 }, "evidence": [ { "id": "E1B987", "url": "https://omabrowser.org/oma/group/E1B987/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0PK84-1", "protein_name": "Palmitoyltransferase ZDHHC22", "gene_name": "Zdhhc22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRLLNVVAPAYFLCISLVTFVLQLFLFLPSMREDPTATPLFSPAVLHGALFLFLSANALGNYVLVIQNSPDDLGTCQGTMSQRPQCPPPSTHFCRVCSRVTLRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVAYISAVLSISFAHPLAFLTLLPTSISQFFSGAVLGSDMFVILMLYLWFAVGLACAGFCCHQLLLILRGQTRYQVRKGMAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGTESSKQQDK", "length": 263 }, "evidence": [ { "id": "E1B987", "url": "https://omabrowser.org/oma/group/E1B987/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2TGI8-1", "protein_name": "Palmitoyltransferase ZDHHC22", "gene_name": "Zdhhc22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLALRLLNVVAPAYFLCISLVTFVLQLFLFLPSMREDPTATPLFSPAVLHGALFLFLSANALGNYILVVQNSPDDLGACQGTSSQRPQRPPPSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVAYISAVLSISFAHPLAFLTLLPTSISQFFSGAVLGSDMFVILMLYLWFAVGLACAGFCCHQLLLILRGQTRYQVRKGVAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGTESSKQQDK", "length": 263 }, "evidence": [ { "id": "E1B987", "url": "https://omabrowser.org/oma/group/E1B987/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N966-1", "protein_name": "Palmitoyltransferase ZDHHC22", "gene_name": "ZDHHC22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLALRLLNVVAPAYFLCISLVTFVLQLFLFLPSMREDPAAARLFSPALLHGALFLFLSANALGNYVLVIQNSPDDLGACQGASARKTPCPSPSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYISAVLSISFAHPLAFLTLLPTSISQFFSGAVLGSEMFVILMLYLWFAIGLACAGFCCHQLLLILRGQTRHQVRKGVAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGSESSKQQDK", "length": 263 }, "evidence": [ { "id": "E1B987", "url": "https://omabrowser.org/oma/group/E1B987/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "X1WBB5-1", "protein_name": "Palmitoyltransferase ZDHHC22", "gene_name": "zdhhc22", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKLKLLNTIAPAYFYAATVVTFALHFLLFTPTIFQSSDVTINPAMLAHISIFLFLMGNALGNYIMTIRNPSESANETVIPVCSPDCPDRIDAHYLLNGRHFCKVCKKVILKRDHHCFFTGNCIGNRNMRYFIMFSIYTSSSCLYSLVIGVAYLTIEYSISFENPLTFLTLLPLSTGYFFLGLISGLQFFLVIMLYIWLGIGLVSVGFCCQQLLLVARGQTWCELQKGQLSECRGTWRANLTDVFGSHWVLGLFVPVPTVETVPGNWQVYHDHKHD", "length": 276 }, "evidence": [ { "id": "E1B987", "url": "https://omabrowser.org/oma/group/E1B987/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1B987", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1B987", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1B987", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "E1B987", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "E1B987", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "E1B987", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3X756-1", "E1BPA5-1", "F1MVC6-1", "E1B987-1", "E1BJK1-1", "F6R785-1", "A0AAA9TDW4-1", "A0AAA9TVJ9-1", "A0AAA9TM40-1", "E1B6X9-1", "E1BKA0-1", "E1BK60-1", "Q58CU4-1", "A2VDT6-1", "A0AAF6ZH94-1", "A0AAA9RZ07-1", "Q0VC89-1", "E1BLT8-1", "G3MXF3-1", "P15103-1", "Q2HJ95-1", "Q58DA8-1", "A0A3Q1M794-1", "A0A3Q1LVW6-1", "Q58DT3-1", "A0A3Q1M403-1", "A0ABI0NXA5-1" ], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LVW6", "gene_name": "ZDHHC13", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1LVW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVW6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1LVW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVW6" } ] } ] }, { "uniprot_ac": "A0A3Q1M403", "gene_name": "", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] } ] }, { "uniprot_ac": "A0A3Q1M794", "gene_name": "ZDHHC3", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M794" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1M794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M794" } ] } ] }, { "uniprot_ac": "A0AAA9RZ07", "gene_name": "ZDHHC8", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9RZ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ07" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9RZ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ07" } ] } ] }, { "uniprot_ac": "A0AAA9TDW4", "gene_name": "ZDHHC7", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TDW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDW4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TDW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDW4" } ] } ] }, { "uniprot_ac": "A0AAA9TM40", "gene_name": "ZDHHC18", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM40" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM40" } ] } ] }, { "uniprot_ac": "A0AAA9TVJ9", "gene_name": "ZDHHC23", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TVJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TVJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ9" } ] } ] }, { "uniprot_ac": "A0AAF6ZH94", "gene_name": "ZDHHC9", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAF6ZH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZH94" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAF6ZH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZH94" } ] } ] }, { "uniprot_ac": "A0ABI0NXA5", "gene_name": "ZDHHC15", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0ABI0NXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0ABI0NXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5" } ] } ] }, { "uniprot_ac": "A2VDT6", "gene_name": "ZDHHC21", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A2VDT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A2VDT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT6" } ] } ] }, { "uniprot_ac": "E1B6X9", "gene_name": "ZDHHC12", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1B6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1B6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X9" } ] } ] }, { "uniprot_ac": "E1B987", "gene_name": "ZDHHC22", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ] } ] }, { "uniprot_ac": "E1BJK1", "gene_name": "ZDHHC17", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ] } ] }, { "uniprot_ac": "E1BK60", "gene_name": "ZDHHC14", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ] } ] }, { "uniprot_ac": "E1BKA0", "gene_name": "ZDHHC4", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BKA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA0" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BKA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA0" } ] } ] }, { "uniprot_ac": "E1BLT8", "gene_name": "ZDHHC5", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BLT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLT8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BLT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLT8" } ] } ] }, { "uniprot_ac": "E1BPA5", "gene_name": "ZDHHC24", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BPA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA5" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BPA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA5" } ] } ] }, { "uniprot_ac": "F1MVC6", "gene_name": "", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "F1MVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "F1MVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC6" } ] } ] }, { "uniprot_ac": "F6R785", "gene_name": "ZDHHC1", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ] } ] }, { "uniprot_ac": "G3MXF3", "gene_name": "ZDHHC2", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "G3MXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXF3" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "G3MXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXF3" } ] } ] }, { "uniprot_ac": "G3X756", "gene_name": "", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "G3X756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "G3X756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ] } ] }, { "uniprot_ac": "P15103", "gene_name": "GLUL", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] }, { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] } ] }, { "uniprot_ac": "Q0VC89", "gene_name": "ZDHHC20", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] } ] }, { "uniprot_ac": "Q2HJ95", "gene_name": "ZDHHC6", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q2HJ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ95" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q2HJ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ95" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q2HJ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ95" } ] } ] }, { "uniprot_ac": "Q58CU4", "gene_name": "ZDHHC16", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q58CU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58CU4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q58CU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58CU4" } ] } ] }, { "uniprot_ac": "Q58DA8", "gene_name": "ZDHHC9", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q58DA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DA8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q58DA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DA8" } ] } ] }, { "uniprot_ac": "Q58DT3", "gene_name": "ZDHHC4", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q58DT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DT3" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q58DT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DT3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B987-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 263, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B987-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B987" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987" }, { "id": "PS50156", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SSD", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 154, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], 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"NP_001376955", "name": "olfactory receptor family 1 subfamily P member 1", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376955" }, "gene_names": [ { "name": "OR1P1", "type": "recommended", "evidence": [ { "id": "E1B9C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9C7" } ] }, { "name": "OR1P1", "type": "synonym", "evidence": [ { "id": "NP_001376955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376955" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1B9C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9C7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1P1", "type": "synonym", "evidence": [ { "id": "NP_001376955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376955" } ] }, { "name": "olfactory receptor family 1 subfamily P member 1", "type": "synonym", "evidence": [ { "id": "NP_001376955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376955" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376955", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376955" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1B9C7", "url": "https://www.uniprot.org/uniprotkb/E1B9C7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B9C7", "url": "https://www.uniprot.org/uniprotkb/E1B9C7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR1P1", "url": "https://www.uniprot.org/uniprotkb/E1B9C7", "locus": { "chromosome": "19", "start_pos": 23978589, "end_pos": 23977636, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019391", "url": "https://www.ensembl.org/id/ENSBTAG00000019391" } ] } } ], "crossref": [ { "id": "E1B9C7", "url": "https://alphafold.ebi.ac.uk/entry/E1B9C7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "520835", "url": "https://www.ncbi.nlm.nih.gov/gene/520835", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:520835", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520835", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376955", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376955", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1B9C7", "url": "https://www.uniprot.org/uniprotkb/E1B9C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9C7-1", "url": "https://www.uniprot.org/uniprotkb/E1B9C7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGNQSSVFEFLLWGLSEQPEQQHRLFLLFLWMYLVTVAGNLLIILAIGTDTRLHTPMYFFLASLSCADILFISTTVPRALVNIQTQNRSISYVECLTQLYFFLTFGDMDIFILTTMAYDRYVAICHPLHYAMVMSRRCCIILVTACWTLTSLVAMTHTFLIFRLSFCSKKIIPDFFCDLGPLMKVSCSDTQVNERVLLFLGGAVILIPFGLILVSYIRIVSAILRVPSAQGRYKAFSTCGAHLAVVALFFGTVIRAYLWPSSSSSSSIEEDTAAAVMYTVVTPLLNPFIYSLRTKDMQGALGRLLRGKVSFSCGQ", "length": 317, "header": "tr|E1B9C7-1|E1B9C7_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1P1 PE=3 SV=4 CANONICAL=E1B9C7-1" }, "isoforms": [ { "isoform_ac": "E1B9C7-1", "url": "https://www.uniprot.org/uniprotkb/E1B9C7/entry#E1B9C7-1", "sequence": { "sequence": "MAGGNQSSVFEFLLWGLSEQPEQQHRLFLLFLWMYLVTVAGNLLIILAIGTDTRLHTPMYFFLASLSCADILFISTTVPRALVNIQTQNRSISYVECLTQLYFFLTFGDMDIFILTTMAYDRYVAICHPLHYAMVMSRRCCIILVTACWTLTSLVAMTHTFLIFRLSFCSKKIIPDFFCDLGPLMKVSCSDTQVNERVLLFLGGAVILIPFGLILVSYIRIVSAILRVPSAQGRYKAFSTCGAHLAVVALFFGTVIRAYLWPSSSSSSSIEEDTAAAVMYTVVTPLLNPFIYSLRTKDMQGALGRLLRGKVSFSCGQ", "length": 317, "header": "tr|E1B9C7-1|E1B9C7_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1P1 PE=3 SV=4 CANONICAL=E1B9C7-1" }, "locus": { "chromosome": "19", "start_pos": 23978586, "end_pos": 23977636, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025838.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025838.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025838.7", "url": "https://www.ensembl.org/id/ENSBTAP00000025838.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:520835", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520835", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1B9C7", "url": "https://www.uniprot.org/uniprotkb/E1B9C7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "E1B9C7", "url": "https://www.uniprot.org/uniprotkb/E1B9C7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1B9C7", "url": "https://www.uniprot.org/uniprotkb/E1B9C7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1B9C7", "url": "https://www.uniprot.org/uniprotkb/E1B9C7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B9C7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 317, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B9C7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B9C7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B9C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9C7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 292, "start_aa": "Gly", "end_aa": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR32546:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32546:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22572", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22572", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1B9D3", "url": "https://www.uniprot.org/uniprotkb/E1B9D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9D3-1", "url": "https://www.uniprot.org/uniprotkb/E1B9D3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 2418, "header": "tr|E1B9D3-1|E1B9D3_BOVIN Isoform 1 of G protein-coupled receptor 179 OS=Bos taurus OX=9913 GN=GPR179 PE=3 SV=2 CANONICAL=E1B9D3-1" }, "locus": { "chromosome": "19", "start_pos": 39005073, "end_pos": 38989591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002360.5", "url": "https://www.ensembl.org/id/ENSBTAT00000002360.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002360.4", "url": "https://www.ensembl.org/id/ENSBTAP00000002360.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1519, "start_aa": "Thr", "end_pos": 1519, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1519", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cell tip", "id": "GO:0051286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051286", "evidence": [ { "database": "UniProtKB", "id": "E1B9D3", "url": "https://www.uniprot.org/uniprotkb/E1B9D3" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "E1B9D3", "url": "https://www.uniprot.org/uniprotkb/E1B9D3" } ], "pmid": "" }, { "name": "dendrite terminus", "id": "GO:0044292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044292", "evidence": [ { "database": "UniProtKB", "id": "E1B9D3", "url": "https://www.uniprot.org/uniprotkb/E1B9D3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1B9D3", "url": "https://www.uniprot.org/uniprotkb/E1B9D3" } ], "pmid": "" }, { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "E1B9D3", "url": "https://www.uniprot.org/uniprotkb/E1B9D3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "E1B9D3", "url": "https://www.uniprot.org/uniprotkb/E1B9D3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1623, "end_pos": 1625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 725, "end_pos": 727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 893, "end_pos": 895, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B9D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D3" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 444, "end_pos": 714, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1519 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 1623, "end_pos": 1625 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 725, "end_pos": 727 }, { "start_pos": 893, "end_pos": 895 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", 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"E1B9D6-1", "uniprot_ac": "E1B9D6", "uniprot_id": "E1B9D6_BOVIN", "mass": { "chemical_mass": 35088.0, "monoisotopic_mass": 35088.0 }, "refseq": {}, "gene_names": [ { "name": "OR1G4", "type": "recommended", "evidence": [ { "id": "E1B9D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D6" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1B9D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1B9D6", "url": "https://www.uniprot.org/uniprotkb/E1B9D6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, 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"https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1B9D6", "url": "https://www.orthodb.org/?gene=E1B9D6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1B9D6", "url": "https://www.uniprot.org/uniprotkb/E1B9D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9D6-1", "url": "https://www.uniprot.org/uniprotkb/E1B9D6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEWENLTSVSEFFLLGLSQQPEQQWPLFGLFLSMYLVTVTGNLLIILAITAHAQLHTPMFFFLANLSLTDICFVSTTIPKTLANIWAQNQVISYTGCLSQLYFFLMFGMLEASLLAVMAYDRYVALCYPLHYIMVMSPGLCGFLVSASWVTNALHSLLHTLLMSSLSFCAHQEIAHFFCDINPLLSLSCTDPFINELVIFTVGGLMGLVCVLCLVISYAYIFSTILKIPSAQGKWKAFSTCSSHLSVVSLYFGSSFCVYFSPLSNHSAQKDAVASVMYTVVTPMLNPFIYSLRNRDIKSSLKKLMWARKIQSF", "length": 313, "header": "tr|E1B9D6-1|E1B9D6_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1G4 PE=3 SV=4 CANONICAL=E1B9D6-1" }, "isoforms": [ { "isoform_ac": "E1B9D6-1", "url": "https://www.uniprot.org/uniprotkb/E1B9D6/entry#E1B9D6-1", "sequence": { "sequence": "MEWENLTSVSEFFLLGLSQQPEQQWPLFGLFLSMYLVTVTGNLLIILAITAHAQLHTPMFFFLANLSLTDICFVSTTIPKTLANIWAQNQVISYTGCLSQLYFFLMFGMLEASLLAVMAYDRYVALCYPLHYIMVMSPGLCGFLVSASWVTNALHSLLHTLLMSSLSFCAHQEIAHFFCDINPLLSLSCTDPFINELVIFTVGGLMGLVCVLCLVISYAYIFSTILKIPSAQGKWKAFSTCSSHLSVVSLYFGSSFCVYFSPLSNHSAQKDAVASVMYTVVTPMLNPFIYSLRNRDIKSSLKKLMWARKIQSF", "length": 313, "header": "tr|E1B9D6-1|E1B9D6_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1G4 PE=3 SV=4 CANONICAL=E1B9D6-1" }, "locus": { "chromosome": "19", "start_pos": 23915620, "end_pos": 23914682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052917.4", "url": "https://www.ensembl.org/id/ENSBTAT00000052917.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049810.4", "url": "https://www.ensembl.org/id/ENSBTAP00000049810.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1B9D6", "url": "https://www.uniprot.org/uniprotkb/E1B9D6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "E1B9D6", "url": "https://www.uniprot.org/uniprotkb/E1B9D6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1B9D6", "url": "https://www.uniprot.org/uniprotkb/E1B9D6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1B9D6", "url": "https://www.uniprot.org/uniprotkb/E1B9D6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B9D6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B9D6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B9D6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B9D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1B9D7-1", "uniprot_ac": "E1B9D7", "uniprot_id": "E1B9D7_BOVIN", "mass": { "chemical_mass": 113606.0, "monoisotopic_mass": 113606.0 }, "refseq": {}, "gene_names": [ { "name": "DSG4", "type": "recommended", "evidence": [ { "id": "E1B9D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D7" } ] } ], "protein_names": [ { "name": "Desmoglein 4", "type": "synonym", "evidence": [ { "id": "E1B9D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.", "evidence": [ { "database": "UniProtKB", "id": "E1B9D7", "url": "https://www.uniprot.org/uniprotkb/E1B9D7#function" }, { "database": "UniProtKB", "id": "RU004358", "url": "https://www.uniprot.org/uniprotkb/RU004358#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B9D7", "url": "https://www.uniprot.org/uniprotkb/E1B9D7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DSG4", "url": "https://www.uniprot.org/uniprotkb/E1B9D7", "locus": { "chromosome": "24", "start_pos": 25726777, "end_pos": 25767053, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040126", "url": "https://www.ensembl.org/id/ENSBTAG00000040126" } ] } } ], "crossref": [ { "id": "E1B9D7", "url": "https://alphafold.ebi.ac.uk/entry/E1B9D7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000040126", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000040126", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000233", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000233", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PEPMIHG", "url": "https://omabrowser.org/oma/group/PEPMIHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B9D7", "url": "https://www.orthodb.org/?gene=E1B9D7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24025:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24025:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1B9D7", "url": "https://www.uniprot.org/uniprotkb/E1B9D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9D7-1", "url": "https://www.uniprot.org/uniprotkb/E1B9D7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDWLLFRNFCLLIILMVVLEVNSEFVVEVKELDAENGTAKWQTVRRQKREWIKFAAACREGEDNSKRNPIARIRSDCEVNQKITYRISGAGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNPPVFTQNVYTASIEENSDANTLVVKLSATDADEDNHLNSKIAYKIVSQEPAGSPMFIMNRYTGEVCTTSNLLDREQHSMYNLLVRGSDRDGATDGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRFQAIDLDEEGTDNWLAKYLILSGNDGNWFDIQTDPQTNEGILKVIKTLDYEQVPNIHLSIGVKNQAEFHHSVASQFRMHSTPVRIQVVNVREGPAFQPNSMTFSVREGLKGNSLLNFVLGTYTAIDLDTGNPATNVRYIIGHDAGNWLKIDSRTGEIQFSREFDKKSKYITNGIYTAEILAIDDGSLKTATGTICIEVPDVNDYCPVIVAERETICIASPSILISAAGVNSHPYGSPFTFCVVNEPPGTADIWDITSVNATSAILKAEQTLYSAYYEIPILVKDSFNRACELPQIIELRACDCDINHVCLYSGITDVSTGDGSSVTSVSVTDDQTEASNVGMGSTGIGMITMGVLLLLLAPLLLLLCCCCKRKQPEGLGTSFAPVPEGGEGVVQSWRIEGAHPEDRDVSNICVPMTASNTQDRMDSSEIYTNTYAGGGTVEGGVSGVELNTGLGAAAGLAAGGAAGTAGRRSSAVGIQRDYGDTSLNLAFLDSYFSEKAYAYAGEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESHMETLDPKFKTLAEICLNTEIDPFPSQQSCIPISTDLPLLGPNYFVNESSGMTLSEAEFKEEMAIPEPMMHGDIVVTETYTTADPCMQPTTIVFDPQLAPNVVVTETVMAPVYEVQGNICVPAELANTHNVIYAERVVSSPGRPDVSSSSMSDGCRGPVMSGGILVGPEIQLTQMMSPDIRISQTIGSTSPVTSRHRVTRYSNIHYSQQ", "length": 1041, "header": "tr|E1B9D7-1|E1B9D7_BOVIN Isoform 1 of Desmoglein 4 OS=Bos taurus OX=9913 GN=DSG4 PE=4 SV=1 CANONICAL=E1B9D7-1" }, "isoforms": [ { "isoform_ac": "E1B9D7-1", "url": "https://www.uniprot.org/uniprotkb/E1B9D7/entry#E1B9D7-1", "sequence": { "sequence": "MDWLLFRNFCLLIILMVVLEVNSEFVVEVKELDAENGTAKWQTVRRQKREWIKFAAACREGEDNSKRNPIARIRSDCEVNQKITYRISGAGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNPPVFTQNVYTASIEENSDANTLVVKLSATDADEDNHLNSKIAYKIVSQEPAGSPMFIMNRYTGEVCTTSNLLDREQHSMYNLLVRGSDRDGATDGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRFQAIDLDEEGTDNWLAKYLILSGNDGNWFDIQTDPQTNEGILKVIKTLDYEQVPNIHLSIGVKNQAEFHHSVASQFRMHSTPVRIQVVNVREGPAFQPNSMTFSVREGLKGNSLLNFVLGTYTAIDLDTGNPATNVRYIIGHDAGNWLKIDSRTGEIQFSREFDKKSKYITNGIYTAEILAIDDGSLKTATGTICIEVPDVNDYCPVIVAERETICIASPSILISAAGVNSHPYGSPFTFCVVNEPPGTADIWDITSVNATSAILKAEQTLYSAYYEIPILVKDSFNRACELPQIIELRACDCDINHVCLYSGITDVSTGDGSSVTSVSVTDDQTEASNVGMGSTGIGMITMGVLLLLLAPLLLLLCCCCKRKQPEGLGTSFAPVPEGGEGVVQSWRIEGAHPEDRDVSNICVPMTASNTQDRMDSSEIYTNTYAGGGTVEGGVSGVELNTGLGAAAGLAAGGAAGTAGRRSSAVGIQRDYGDTSLNLAFLDSYFSEKAYAYAGEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESHMETLDPKFKTLAEICLNTEIDPFPSQQSCIPISTDLPLLGPNYFVNESSGMTLSEAEFKEEMAIPEPMMHGDIVVTETYTTADPCMQPTTIVFDPQLAPNVVVTETVMAPVYEVQGNICVPAELANTHNVIYAERVVSSPGRPDVSSSSMSDGCRGPVMSGGILVGPEIQLTQMMSPDIRISQTIGSTSPVTSRHRVTRYSNIHYSQQ", "length": 1041, "header": "tr|E1B9D7-1|E1B9D7_BOVIN Isoform 1 of Desmoglein 4 OS=Bos taurus OX=9913 GN=DSG4 PE=4 SV=1 CANONICAL=E1B9D7-1" }, "locus": { "chromosome": "24", "start_pos": 25766802, "end_pos": 25727781, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048414.4", "url": "https://www.ensembl.org/id/ENSBTAT00000048414.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045458.2", "url": "https://www.ensembl.org/id/ENSBTAP00000045458.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-BTA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "F1R480-1", "protein_name": "Desmoglein-2.1-like isoform X1", "gene_name": "si:ch73-74h11.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPVWLGQILLVLLMFRIVGSKANIRSHRKKREWILPPTRLYENVDYTKEEYVAKIRSDKDINWQVVEYGLTGHGANKLPYNLFVINPENGYVKVTGLLDREKTSSYNLTGIAKYRNGSIAEENIMLKIKVEDQNDNFPIFREQSGSVKESSKIGTPVMQIRATDADEEGTINSKIAYSIIKQSPAESGNMFSIDRATGNVYVKEKILDRERHDKYTLIVQGVDMDGHPSGNTGTGTVHINILDINDNVPTLEKEEYSGSVDEGVVDVVVMRIKAQDKDLKFTDNWLAVFDILKGNEDNLFSIETDPKTNEGILKLIKPVDFEKVKELDLNLVISNVAPFINGSALELDVNLDKGGAGAGAGAGVGAGLGVGLGVGLGLGLDAGLDAGPNAGLGAGLDLGAGLDAGLDAELDAGLDAGLDAGLDAGLDAGVDLGAGMDAGGDVGLKPGVNPGAKPGPSLGVKPGPKPGPKPGTKPGTSPSGKPVSDPDKKPAGKGYPVKISVNNLPDGPGFSPSVKDFPVSEDPNEDFPVVLGTFAALDGDTGEPAENVRYAKGHDPDNWITIDEETAEIKLTKAPDRESKFLVNGTYFAKIICMTQDVPAKTATGTIALKVEDTNDHCPTLTSCYHQTCDNNKVVNVTAFDEDADPNATPFQFALIEEESVGKWQMVPINGTTVSFHTQETLWPGIYELTVKITDAQGLACPDNQKFEVEVCSCEEKSSCGPRLAAQRSVPLKIGKPALGLFLSGAALLLLVPFLLLFCQCGTVNEFTDLPFDAKEYLIPYHTEGIGEDKEIPALSGLAATIDQKQLLQVSNTVSKMHFQTSVANDSRMLNQDINNDGLTESDGRIWYRENTISTANHRNSALYSASFIQEKQDIYGDMALGDVFLNEYFSQKASSAAANPPLADGLLVYEYVGQGSPAGSLGCCSILESDDDLEFLNNLGSKFLTLAEICNPPKPSLPPTKTEQVVKSVETSYKSESSVSTSTIQVTKEKTAPQQVQQSSVTKVETVNTFATLPTASQTVYVEQQPLFYFVEEQMPNISFVESPTQGLFVINGNHGMEGLILQDGKISQRQGQQAMYLVNGAAVAANQPIQFQTEGQEQEGVLGFSSLSSPIGSHKGVVLMQTHFQGKAVQGDAGRSPAKLEKQNKKTLSTSLSK", "length": 1157 }, "evidence": [ { "id": "E1B9D7", "url": "https://omabrowser.org/oma/group/E1B9D7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7TMD7-1", "protein_name": "Desmoglein-4", "gene_name": "Dsg4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWLLFRNICLLILFMVVLGVNSEFIVEVKELDIENGTTTWQTVRRQKREWIKFAAACREGEDNSKRNPIARIRSDCEVSQRITYRISGAGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIHCRALNSRGEDLERPLELRVKVMDVNDNPPVFTQNVYTANIEENSDANALVVKLSATDADEDNHLNSKIAYKIISQEPAGAPMFMVNRYTGEVRTMSNFLDREQHSMYNLLVRGSDRDGATDGLSSECDCRIKILDVNDNFPILEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYSILSGNDGNWFEIQTDPKTNEGILKVVKMLDYEQEPNIYLSIGVRNQAEFHHSVASQFQMHSTPVRIQVVNVREGPTFSPSSMTFSLRGGMRGASLMNYVLGTYTAIDMDTGNPATNVRYVIGHDAGSWLKVDSRTGEIQFSREFDMKSKYITDGIYAAQILAIDDGSGRTATGTICIEIPDANDYCPVIYAESRSVCTHASSVRIYVNDHSFGSPFTFCVVDESPDIANIWDIRSINGTSAILMTEQTLSPGPYQIPILVKDSHNRACELPQTVLLDACFCDDHHVCLHSSTTGIYTGDITWVTDDMYGTVTDDGVRQSNVGLGPAGIGMIILGLLLLLLSPLLLLMCCCKRRQPEGLGTRFAPVPEGGEGVMQPWRIEGAHPEDRDVSNICVPMTASNTQDRIDSSEIYTNTYAGGGTVEGGVSGVELNTGVGTATGMVAAGATGTLRKRSSTIGTLREYQDTGMNMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGAGSPVGSIGCCSWIVDDLDESYIETLDPKFRTLAEICLDTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGMTLSEAEFQAEMAAASEPMIHGDIIVTETYTTSDPCVQPTTIVFDSQIPPNVVVTETVMAPVYDVQGNICVPAEIANTHNVYYAERVVASPGIPDMGNSNISDACIGPVMSGGILVGPEIQVTQMMSPDIHISQTTGSTSPMTSQHRVTRYSNMHYSRQ", "length": 1041 }, "evidence": [ { "id": "E1B9D7", "url": "https://omabrowser.org/oma/group/E1B9D7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86SJ6-1", "protein_name": "Desmoglein-4", "gene_name": "DSG4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGLTPSEVEFQEEMAASEPVVHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGSTSPMTSRHRVTRYSNIHYTQQ", "length": 1040 }, "evidence": [ { "id": "E1B9D7", "url": "https://omabrowser.org/oma/group/E1B9D7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1B9D7", "url": "https://www.uniprot.org/uniprotkb/E1B9D7" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "E1B9D7", "url": "https://www.uniprot.org/uniprotkb/E1B9D7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1B9D7", "url": "https://www.uniprot.org/uniprotkb/E1B9D7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "E1B9D7", "url": "https://www.uniprot.org/uniprotkb/E1B9D7" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "E1B9D7", "url": "https://www.uniprot.org/uniprotkb/E1B9D7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 879, "end_pos": 881, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1B9D7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1041, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1B9D7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1B9D7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B9D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D7" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 157, "start_aa": "Asp", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 879, "end_pos": 881 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1B9G8-1", "uniprot_ac": "E1B9G8", "uniprot_id": "E1B9G8_BOVIN", "mass": { "chemical_mass": 150217.0, "monoisotopic_mass": 150217.0 }, "refseq": { "ac": "XP_010805170", "name": "rho guanine nucleotide exchange factor 18 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010805170" }, "gene_names": [ { "name": "ARHGEF18", "type": "recommended", "evidence": [ { "id": "E1B9G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ] }, { "name": "ARHGEF18", "type": "synonym", "evidence": [ { "id": "XP_010805170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010805170" } ] } ], "protein_names": [ { "name": "Rho/Rac guanine nucleotide exchange factor 18", "type": "synonym", "evidence": [ { "id": "E1B9G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9G8/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 18 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_010805170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010805170" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARHGEF18", "url": "https://www.uniprot.org/uniprotkb/E1B9G8", "locus": { "chromosome": "7", "start_pos": 16345155, "end_pos": 16245814, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040507", "url": "https://www.ensembl.org/id/ENSBTAG00000040507" } ] } } ], "crossref": [ { "id": "ENSBTAG00000040507", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000040507", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15794", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15794", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "522521", "url": "https://www.ncbi.nlm.nih.gov/gene/522521", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:522521", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522521", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QSFICRR", "url": "https://omabrowser.org/oma/group/QSFICRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B9G8", "url": "https://www.orthodb.org/?gene=E1B9G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47440", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47440", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47440:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47440:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17838", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17838", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2173791", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2173791", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010805170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010805170", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9G8-1", "url": "https://www.uniprot.org/uniprotkb/E1B9G8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDEQEDGIPGLLGGSESSEDLSLDLGALQGSEYLQDLGLEVLSHSQPGGARDSGPPSEEARGETPRGETPLSSAARSQGLARRRSWERSRSCSESRQRLSIESSAVNEGPFLPRTLASLALNLPGEGLQAWTQGCLPGGGTPAEQPSKECDSPEKRVRSRSVPVSFDEISSLEIFPALEVPPPAVQGLDPPVLECMEKDHVEPNHVLIVQQVLEELRQYHGARQRARLSVCPGGAASNLTWFEFLSESEDSMGKTERSDRGTKVKRSLSSLRNRVTRQKEKGKTPVHQKDKGQDARERKECINGHQLARGTFSGHSSCPMCGKPFLSSASLKEHPRATLLSDGSPRPTRNVGMTVSQKGGPQPAPSPAGTGTRLGPLTGEMDETDTLFPKLKQVADDSLFLTSSSTEPIFIEDPYTASLRGEVEADTHEFEAESWSLSVDPEYVKKQKREVVKRQDVLYELMQTEAHHVRTLKIMLKVYSRALREELQFSPKAVSRLFPGADDLLEVHSHFLCRLKERRLESLEEGSAHNYIIRKIGDLLLQQFSGENGERMKEKYSVFCSGHNDAVSHYKLLLQQNKKFQNLIKRIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGSEDHRDLTQALNLIKDIISQVDARVSECEKGQRLREIAGKMDLKSSSKLKNGLTFRKEDMLQRQLHLEGTLCWKTTSGRLKDVLAVLLTDVLLLLQEKDQKYVFASVDSKRPVISLQKLIVREVANEEKAMFLISASLHGPEMYEIYTSSKEDRNTWMAHIRRAVESCPDEEEGPFSEAEEEKKVVETRAVRLRDFQERLNRKDQQIAQSLSEKQQIYLEMAEMSGLEDLALSRLLFRGGDPPENLQGELILKSAMSEIEDIQSFICRRLGNAYCQAEDGGSAGSPGKDGSLQKNMCSSDLSPRDWQGLVSSLDSRPGDTQGAPEEASKVAESPGADPGPHPPAVLELELVQRIQTLSQLLLSLQVVIAQQDSYVEIQKAAIQEREKQFRLQSTRGNLLLEQERQRNFEKQREELAGVQKLQGQLRLEQQRWEREREQQRRELDQASARLQQRESELLRLQERLNQEREELERQRQAYQHDLERLREAQRAVERERERLEVLRRLKKQNTAPGALPPEALAETQPLSHTPSFNGNGLDGSMTLTKAPGPRPTSLVSSAGSEYAERPEVARRDSAPAKSEVPIQLLSATNQIQRQAAVQQQIPTKLAASTKGGKDKGGKNRGSQRWDSSASFDLRQPLLLNKLMGKEENTSRNRRSLSPVLPSSTPHQDPSLPAPTPGPADVPTESLPLKTWGPSFPPGAPSSTPVNKEETGKEDVIFF", 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"length": 1345, "header": "tr|E1B9G8-1|E1B9G8_BOVIN Isoform 1 of Rho/Rac guanine nucleotide exchange factor 18 OS=Bos taurus OX=9913 GN=ARHGEF18 PE=4 SV=2 CANONICAL=E1B9G8-1" }, "locus": { "chromosome": "7", "start_pos": 16344151, "end_pos": 16265737, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014311.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014311.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014311.5", "url": "https://www.ensembl.org/id/ENSBTAP00000014311.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1302, "start_aa": "Thr", "end_pos": 1302, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1302", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:522521", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522521", "resource": "KEGG Pathway" }, { "id": "R-BTA-2173791", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2173791", "resource": "Reactome", "description": "TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" }, { "id": "R-BTA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-BTA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A590UK10-1", "protein_name": "Rho guanine nucleotide exchange factor 18", "gene_name": "ARHGEF18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "XTSVKRRLSCLRSRVTRQKEKGKSPAHLKDKGQDARERRECVNGHQLLQGTFSGPSSCPLCGKPFLSSASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQLGPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESDGHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYELMQTEVHHVRTLKIMLKVYSRALQEELQFSSKAIGRLFPCADDLLETHSHFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSGENGERMKEKYGVFCSGHNEAVSHYKLLLQQNKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTEDYEDLTQALNLIKDIISQVDAKVSECEKGQRLREIAGKMDLKSSSKLKNGLTFRKEDMLQRQLHLEGMLCWKTTSGRLKDILAILLTDVLLLLQEKDQKYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASLQGPEMYEIYTSSKEDRNAWMAHIQRAVESCPDEEEGPFSLPEEERKVVEARATRLRDFQERLSMKDQLIAQSLLEKQQIYLEMAEMGGLEDLPQPRGLFRGGDPSETLQGELILKSAMSEIEGIQSLICRQLGSANGQAEDGGSSTGPPRRAETFAGYDCTNSPTKNGSFKKKVSSTDPRPRDWRGPPNSPDLKLSDSDIPGSSEESPQVVEAPGTESDPRLPTVLESELVQRIQTLSQLLLNLQAVIAHQDSYVETQRAAIQEREKQFRLQSTRGNLLLEQERQRNFEKQREERAALEKLQSQLRHEQQRWERERQWQHQELERAGARLQEREGEARQLRERLEQERAELERQRQAYQHDLERLREAQRAVERERERLELLRRLKKQNTAPGALPPDTLAEAQPPSHPPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARRDSAPTENRLAKSDVPIQLLSATNQFQRQAAVQQQIPTKLAASTKGGKDKGGKSRGSQRWESSASFDLKQQLLLNKLMGKDESTSRNRRSLSPILPGRHSPAPPPDPGFPAPSPPPADSPSEGFSLKAGGTALLPGPPAPSPLP", "length": 1089 }, "evidence": [ { "id": "E1B9G8", "url": "https://omabrowser.org/oma/group/E1B9G8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A8V1AFK2-1", "protein_name": "Rho/Rac guanine nucleotide exchange factor 18", "gene_name": "ARHGEF18", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"length": 1567 }, "evidence": [ { "id": "E1B9G8", "url": "https://omabrowser.org/oma/group/E1B9G8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein localization to cell-cell junction", "id": "GO:0150105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150105", "evidence": [ { "database": "UniProtKB", "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ], "pmid": "" }, { "name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ], "pmid": "" }, { "name": "negative regulation of stress fiber assembly", "id": "GO:0051497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", "evidence": [ { "database": "UniProtKB", "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E1B9G8", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1275, "end_pos": 1277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B9G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 317, "end_pos": 348, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1B9G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9G8" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": 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"end_pos": 592 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1B9J0-1", "uniprot_ac": "E1B9J0", "uniprot_id": "E1B9J0_BOVIN", "mass": { "chemical_mass": 34555.0, "monoisotopic_mass": 34555.0 }, "refseq": {}, "gene_names": [ { "name": "OR8G47", "type": "recommended", "evidence": [ { "id": "E1B9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9J0" } ] }, { "name": "OR8G4", "type": "synonym", "evidence": [ { 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:531174", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531174", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NDTAFHP", "url": "https://omabrowser.org/oma/group/NDTAFHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377060", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377060", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1B9N1", "url": "https://www.uniprot.org/uniprotkb/E1B9N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9N1-1", "url": "https://www.uniprot.org/uniprotkb/E1B9N1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSASVPNDTTFHPSTFILLGIPGMRDQHIWAAIPFCSMYILALVGNGTILYIITKERTLHEPMYLFLCLLSITDLVLCSTTLPKMLTIFWLKSHIISYQGCLTQMFFVHTIFATESAVLLAMAFDRYVAICHPLHYASILNAMVIGKIGLACVVRGLLFVFPFVILIERLPFCGHHIIPHTYCEHMSIAKLACASIRPNTIYGLTVALSVTGMDVVLIAASYGLILRAVLRLPSKDAQFRAFSTCGAHICVILVFYAPAFFSFFTHRFGQQVPPHVHIVLANLYLLVPPVLNPLVYGINTKQIRLRIFHFFMGRR", "length": 316, "header": "tr|E1B9N1-1|E1B9N1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR52D3 PE=3 SV=4 CANONICAL=E1B9N1-1" }, "isoforms": [ { "isoform_ac": "E1B9N1-1", "url": "https://www.uniprot.org/uniprotkb/E1B9N1/entry#E1B9N1-1", "sequence": { "sequence": "MVSASVPNDTTFHPSTFILLGIPGMRDQHIWAAIPFCSMYILALVGNGTILYIITKERTLHEPMYLFLCLLSITDLVLCSTTLPKMLTIFWLKSHIISYQGCLTQMFFVHTIFATESAVLLAMAFDRYVAICHPLHYASILNAMVIGKIGLACVVRGLLFVFPFVILIERLPFCGHHIIPHTYCEHMSIAKLACASIRPNTIYGLTVALSVTGMDVVLIAASYGLILRAVLRLPSKDAQFRAFSTCGAHICVILVFYAPAFFSFFTHRFGQQVPPHVHIVLANLYLLVPPVLNPLVYGINTKQIRLRIFHFFMGRR", "length": 316, "header": "tr|E1B9N1-1|E1B9N1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR52D3 PE=3 SV=4 CANONICAL=E1B9N1-1" }, "locus": { "chromosome": "15", "start_pos": 47653079, "end_pos": 47652132, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021454.7", "url": "https://www.ensembl.org/id/ENSBTAT00000021454.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021454.7", "url": "https://www.ensembl.org/id/ENSBTAP00000021454.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:531174", "name": "", "url": 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"Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1B9N6", "url": "https://www.uniprot.org/uniprotkb/E1B9N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9N6-1", "url": "https://www.uniprot.org/uniprotkb/E1B9N6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFKGLSKSSQGKGSPKGSPAKGSPKGSPNKHSRAATQELALLISRMQANADQVERDILETQKKLQQDRQHSEQRQALQHRQEVGRSLKEAEVLLKDLFLDVDKAQRLKHPQAEEIEKDIKQLHERVTQECAEYRALYEKMVLPPDVGPRVDWARVLEQKQKQVCEGQYGPGMAELEQQVAEHNILQKEIEAYGQQLRTLVGPDAATIRSQYRDLLKAASWRGQSLGSLYTHLQGCTRQLNALAQQQQRILQQDWSDHLADPAGVRREYEHFKQHELLSQEQRVNQLEDDGERMVELGHPAVGPIQAHQEALKVEWQNFLNLCICQESQLQHVEDYRRFQEEADSVSQTLAKLNSSLDSQYSPAPEGPPGALMEMLRQLEAEEKQLTMAEKTLKDLQLQSQGVAPLPQRRNLPLQPLRVDSICDWDSGEVQLLRGEQYTLVDNTDPHTWVVQGQAGEPKRAPAACFCIPALDPPRPGPALQALKQKLTAVQSRLKASAKEPLRPSQQAPSSSGPPDPQAQKLLTQMTRLEEDLGQIEKQLLAWARAPLSRTTPLEDLEGRIQNHQGTAQRLQSLGAEKEAAQQKCEAFLSGQPSGPAALHLPVVLNSVKNKYRDVQVLCSLYGEKAKAALGLERQIRDADKVIRGFESALAQEAPIPAGPGALQERVSELKRRRRELLEQQACVLGLHRQLKAVEHMCSALQNNFCEFCKDLPHQQRQVRALTDRYHAVGDQLDLREKMMQDAGLTYQQFKNCTDNLNAWLERLPHNKVRPSDGPSQIAYKLQAQKRLLQEIQGRKQDRATASRLSQHLQVALQDYELQADTYRGSLEPTQVGSAPKRPRVAPLQDSIQAQEKNLTKAYTEVAAAHQQQLHQLEFARKILEKKELNEDIQVTPNAQQGSESPARGGRKSEALRSQLEEERKRVAQVQRELEEQRSQLLQLKTQRPVEKLEEKEVVEFYRDPQLESNLSRVKSQVEDEGKKQAGLQADLEAVAQKVMQLESQRKATEPHLLTKEVTQIERDPGLDSQAAQLKSELQLLQEENTAVLAQLEALKAELLALEQKEVNVKETVVVKEVVKVEKDLEMLQAAQALRLKIQEDVAQRKGAEDAVAKLQARVVELEAAIRTVEPKVIVKEVKKVEQDPRLLQEASRLRSLLEVQRSENEVLARELKELHSKHSAAEKQKPRVDLQERVQETFRVDPETEREIAQLRAELQETGRKRNGTEQEVERLLSELVVLRAQKPTVEYKEVTQELVRHEKNPELLREIDRLKAQLNELVNGSGRAQEQLIRLQGERDEWRRERSKVETKTVNKEVVRREKDPVLEQEAQRLRQEVREATQKRRAAEDAVHQLQNKYLLLERRRPEERVVVQEVVEHSRLSQSLDEEAGRRRQLEREVQQLQAAVQEDEGRLSFREDRSKKLAVERELRQLTLKLQELEKRPPAVQERIIMEEVVQLEKDPDLEKSTAALRQDLAQEKTQATEVHRECKNLQVQIDVLQKTKLQEKTIYKEVIRVEKDPMLEGERARVWEALNRERAARESREEEVRRLRERVERAEALGRTWAREEAELQKTRDRASQECRQLQQELRELERQKQQRVLHLQEESKLLSQKTESERQRAAQRGQELSQLESAILREKDRIYEKERTLRDLHTQVSREELNQETQTRETNISTKISILEPETGKDMSPYEAYKRGVIDRSQYLQLQDLECDWEEVTTSGPHGEESVLLDRKSGKQYSIEAALRSRRISKEEYHLYKDGQLPISEFALLVAGETKPCPSLSIGAIISKSPLASPASQSTSLFSPSFSLGLSEDSFPIAGVYDTTTDNKCTIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAVERGLIESGSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPQESVLPHLRVQHLTGGLIDPKKTGRIPVAQAVLSGMISEELAQLLQDEASYEKDLTDPISKERLSYREAMGRCRKDPLSGLLLLPASLEGYRCYRSASPTVPRSLR", "length": 2017, "header": "tr|E1B9N6-1|E1B9N6_BOVIN Isoform 1 of Envoplakin OS=Bos taurus OX=9913 GN=EVPL PE=1 SV=2 CANONICAL=E1B9N6-1" }, "isoforms": [ { "isoform_ac": "E1B9N6-1", "url": "https://www.uniprot.org/uniprotkb/E1B9N6/entry#E1B9N6-1", "sequence": { "sequence": "MFKGLSKSSQGKGSPKGSPAKGSPKGSPNKHSRAATQELALLISRMQANADQVERDILETQKKLQQDRQHSEQRQALQHRQEVGRSLKEAEVLLKDLFLDVDKAQRLKHPQAEEIEKDIKQLHERVTQECAEYRALYEKMVLPPDVGPRVDWARVLEQKQKQVCEGQYGPGMAELEQQVAEHNILQKEIEAYGQQLRTLVGPDAATIRSQYRDLLKAASWRGQSLGSLYTHLQGCTRQLNALAQQQQRILQQDWSDHLADPAGVRREYEHFKQHELLSQEQRVNQLEDDGERMVELGHPAVGPIQAHQEALKVEWQNFLNLCICQESQLQHVEDYRRFQEEADSVSQTLAKLNSSLDSQYSPAPEGPPGALMEMLRQLEAEEKQLTMAEKTLKDLQLQSQGVAPLPQRRNLPLQPLRVDSICDWDSGEVQLLRGEQYTLVDNTDPHTWVVQGQAGEPKRAPAACFCIPALDPPRPGPALQALKQKLTAVQSRLKASAKEPLRPSQQAPSSSGPPDPQAQKLLTQMTRLEEDLGQIEKQLLAWARAPLSRTTPLEDLEGRIQNHQGTAQRLQSLGAEKEAAQQKCEAFLSGQPSGPAALHLPVVLNSVKNKYRDVQVLCSLYGEKAKAALGLERQIRDADKVIRGFESALAQEAPIPAGPGALQERVSELKRRRRELLEQQACVLGLHRQLKAVEHMCSALQNNFCEFCKDLPHQQRQVRALTDRYHAVGDQLDLREKMMQDAGLTYQQFKNCTDNLNAWLERLPHNKVRPSDGPSQIAYKLQAQKRLLQEIQGRKQDRATASRLSQHLQVALQDYELQADTYRGSLEPTQVGSAPKRPRVAPLQDSIQAQEKNLTKAYTEVAAAHQQQLHQLEFARKILEKKELNEDIQVTPNAQQGSESPARGGRKSEALRSQLEEERKRVAQVQRELEEQRSQLLQLKTQRPVEKLEEKEVVEFYRDPQLESNLSRVKSQVEDEGKKQAGLQADLEAVAQKVMQLESQRKATEPHLLTKEVTQIERDPGLDSQAAQLKSELQLLQEENTAVLAQLEALKAELLALEQKEVNVKETVVVKEVVKVEKDLEMLQAAQALRLKIQEDVAQRKGAEDAVAKLQARVVELEAAIRTVEPKVIVKEVKKVEQDPRLLQEASRLRSLLEVQRSENEVLARELKELHSKHSAAEKQKPRVDLQERVQETFRVDPETEREIAQLRAELQETGRKRNGTEQEVERLLSELVVLRAQKPTVEYKEVTQELVRHEKNPELLREIDRLKAQLNELVNGSGRAQEQLIRLQGERDEWRRERSKVETKTVNKEVVRREKDPVLEQEAQRLRQEVREATQKRRAAEDAVHQLQNKYLLLERRRPEERVVVQEVVEHSRLSQSLDEEAGRRRQLEREVQQLQAAVQEDEGRLSFREDRSKKLAVERELRQLTLKLQELEKRPPAVQERIIMEEVVQLEKDPDLEKSTAALRQDLAQEKTQATEVHRECKNLQVQIDVLQKTKLQEKTIYKEVIRVEKDPMLEGERARVWEALNRERAARESREEEVRRLRERVERAEALGRTWAREEAELQKTRDRASQECRQLQQELRELERQKQQRVLHLQEESKLLSQKTESERQRAAQRGQELSQLESAILREKDRIYEKERTLRDLHTQVSREELNQETQTRETNISTKISILEPETGKDMSPYEAYKRGVIDRSQYLQLQDLECDWEEVTTSGPHGEESVLLDRKSGKQYSIEAALRSRRISKEEYHLYKDGQLPISEFALLVAGETKPCPSLSIGAIISKSPLASPASQSTSLFSPSFSLGLSEDSFPIAGVYDTTTDNKCTIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAVERGLIESGSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPQESVLPHLRVQHLTGGLIDPKKTGRIPVAQAVLSGMISEELAQLLQDEASYEKDLTDPISKERLSYREAMGRCRKDPLSGLLLLPASLEGYRCYRSASPTVPRSLR", "length": 2017, "header": "tr|E1B9N6-1|E1B9N6_BOVIN Isoform 1 of Envoplakin OS=Bos taurus OX=9913 GN=EVPL PE=1 SV=2 CANONICAL=E1B9N6-1" }, "locus": { "chromosome": "19", "start_pos": 55644111, "end_pos": 55626318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013898.5", "url": "https://www.ensembl.org/id/ENSBTAT00000013898.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013898.4", "url": "https://www.ensembl.org/id/ENSBTAP00000013898.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GI96-1", "protein_name": "Envoplakin", "gene_name": "Evpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFKGLSKGSPAKGSPKGSPAKGSPKGSPNKHSRAATQELALLISRMQANADQVERDILETQKKLQQDRQNGAQNQALQHQQETGRNLKEAEVLLKDLFLDVDKARRLKHPQAEEIEKDIKQLHERVTQECAEYRALYEKIVLPPDVGPRVDWTRVLEQKQKLICEGHYGPGMAELEQQVAEHNILQREIEAYGQQLRTLVGPDANAIRNQYRDLLKAASWRRQSLGSLYTHLQGCTKQLGALADQQGRILQQDWSDLMPDPAGVRREYEHFKQHELLAQEQSINQLEDDAERMVELGHPAIGPIQAHQEALKMEWQNFLNLCICQESQLQHVEDYRRFQEEADSASQTLAKLSSNLDTKYSFGAGDSSVSPTELLLQLEAEEKQLAIAERTIGELQRRSQEVAPLPQRRNPPKQPLHVDSICDWDSGEVQLLRGERYTLKDNADPYTWVVQGPGGETKSAPAACLCIPAPDPEAVAKASRLASELQTLKQKLSTEKSRLKNASAEHLQQGQQAPAGSAPADPQAQKLLSQMTQLDGDLGQVERQVLSWARSPLNDSSPLKDLEGRIQSCEGTAQHLQNLGAEKEAAQQECEAFLSTKPTGSAALQLPVVLNNVKNKYSDVHSLCYLYGEKAKAALGLEKQIQEADGIIQGFEATLAQEGPIPEGSGALQERVSELQRQRKELLQQQACVLGLHRQLKAAEHACGALQNNFQEFCQDLPRQQRQVRALTDRYHSVGDQLDLREKILQDASLTHQQLKNSRDNLSSWLEQLPHHRVQPSDGPSQIAYKLQAQKRLIQEILGREQDQATVARLTRDLQEALQEYELRADTYRCSLEPTLAVSAPKRLRVISLKENIQAQEKNLTKAYTEVAAAEQQQLHQLEFAKKMLEKKELNEDFQAIHSARQGSGSPAHTKTESEVLKTQLEEERKRVAEVQRELEERRQQLLQLRTQQPVARLEEKEVVEFYRDPQLKSNVLQASSRLEEEGKRRARLQAELEVVAQKVVHLEGKRKAMQPHLLTKEVTQIERDPGLDSQVTQLHNEMQGLRGENAVLAARLEGLKDELLTLEQKEINVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKGAKEAVAKTQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNKNVMLARELQELQDKYRAVEKQKPKVQLQERVSEIFQVHPETEQEILRLRAQLQETGSKKSCVEREVEKLLPELEVLRAQKPVVEYKEVTQEVVRHEKDPVLEKEAERLRQEVREAVQKRRAAEDAVYELQNKYLLLERRRPEEQIVVQEVVVTQKDPKLHEEHSRLSRSLDEEVGRRRQLELEVRQLSASVEEEEAMLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERSTEALRRELDQEKNRVIELHRECKGLQVEVDLLQKTKSQEKTIYKEVIRVEKDPVLESERARVWETLNRERAARQSREEDVRSLKERIDRAEALRRSWSLQKARDQASQDCGRLQRELRELEQQKLQKAQQLQEEGRLLSQKTESERQKAAQRSQALSQLEAAILHEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLSTKICILEPETGNDMSPYEAYKRGIIDRGQYLQLQELECDWEEVTTSSPCGEESVLLDRKSGKQYSIEAALRCRRISKEEYHRYKDGRLPISEFALLVAGETKPSSSLSIGSIISKSPVCSPGPQSTGFFSPGLSLGLTEDSFPIAGVYDTTTDNKCSIKAAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAVEQGLIENTSTQRLLNAQKAFTGIEDPVTRKRLSVGEAIQKGWMPQESVLPHLLVQHLTGGLIDPKRTGRIPVPQAVLCGMISEDLGQLLQDESSYEKDLTDPITKERLSYKEAMGRCHKDPLSGLLLLPAMLEGYRCYRVASPTLPRSCVR", "length": 1969 }, "evidence": [ { "id": "E1B9N6", "url": "https://omabrowser.org/oma/group/E1B9N6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1AQ02-1", "protein_name": "Envoplakin", "gene_name": "EVPL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGAGKDARSVPPAFNRKLQEEVWDTIRGVLSPRAAQHRWGCAAGCGCSLCPLHSPLQPEALSSACCALTAAVPLLLGSVPGPGTAKLHLRGVEPPGAAPGLCRPPLNPRVPSPQPAAPPPRRLQHRSRSHSSMFKAVGKGSPSRSAPGRGSPAKPNKSSSNDLAVLIARMQTNADQVEKDILDTQSLLAQDVSNEQKNKAFEFQAENARNLKEAETLLKDLFLDVDRAKRLKHPQANEIEKDIQQLHERVTQLCAEYRDLYEKLNVPDIGPRVDWTKILDQKMKQVSAGQYGPGMSELEKQIAEHNILQKEIEAYGLQIKNLRCRDVTDLKSQYKDLLKASIWRGQSLGSLYHHLQGCTKELGYLTERQTCILKQDWSDQMTDVQSVRREYEDFKSKELLSQEKFVNNLQDDGDRMIELKHPAVKPIQAHQEALKNEWQNFLNLCICQESQLKSVENYKKFQDDAETVSRSLKKMSSDLDTKYTKFNKDSPGVVSDLLLHLENDEKAVKQAEKSIADLKKRSKEISPLKLRRMRSSQPLTLDTLCDWDAGEVQLTRGDKYTLKDNSNPEMWVVQSSTGVVQEAPSACFSIPPPDPEAIDKVNRLEGELNAVKQKRAAAQSMLRRSHKETVQPSQQVLPKSTPVVQDDPQADQLLGSLDRVGKDLVQVEKEVLNRVRSPVSYTDPTDDLARRIKQQQETTKKLESLGAAKDALQKECETYLSKKPTSTSASQLPVTLNALRSKYSDVSMLSSLYNEKAKAALNLETQIENTDKIVSTFEAKLAQDSIIPASPNALQDRANDLQKMKRDLVAQEDCVLKLNRGLKDAEHSCSAVQNNFQEYCPDLPRQKREVQLLNDRYHAVADQLDQREKTLRNISLTYQQFQNSNENLMFWMNNLPKHQVKTTDGPSQINYKLQAQKRVLEEIESKEPEKNAVIRLSRNVQSTLNDYELQAGKYSSSLDPALTDFAAKRLRVTPLQESIQAQENDVSKHYMELAAENRQQLSRLEFAKKIVEKKEVHEDIQSVHEQTQQSANKAVPSRESEGLKLQLEEERRNVARIEEDLEEHRNKLLMLKTQRPIERVEEKEVVEYYRDPQLESSLTKMTQQIEEEGKKRQSLQEDIEVMSRKLAQMESEKKAVPAQLLTKEITKIEKDPNLDSQAASLRQEIRRLQEESLAAASELEQCKRELHVLERKQPNIREKVVVKELIKTEKNPEMLKSVRNLQLQIDEESFKRKSAEEAIVKVKSKIEEVEKLIDAAEPKIIVKEVKQVEQDPELLKESSKLKALIEEERSKNLALAGELGELQSQCSIAEKQKPRVEVKERVNEIFMVDPETEKEIAHLKRELQEVTLKRTKIDSEVEEALAELSVLRSRKPEVELKEVIEEVVKHEKSPEILREIDRLKQQLNELVNTNGRTQEQLIRLQGERDEWKRERSKVETKLVNKEVIRYENDPLLEKEADRLRQEVRSMSQKRRAAEDAIYDLQNKYMLLERRKPEEKVIVQEVILTQKDPKLRDEHNRLSRSLDEEVSNRRRLERDVQQLRALVEEQEKLLNFQEDRSKRLALEKEMRQITLRIKELEESPAPVQEKIIMEEVVKLEKDPLLEQSASNLRLELDREKMEVLNLQRECKNLQMQVDVLQKAKSQEKTIYKEVIRVEKDRALESERARIWEQLSRERGAKQKAEEEVRRLREKIERAEGMKRTWAREETELQKARNLAIQERASLESELRELERQKQQKVLFLREESKLLNQRTESDRQKKKQLEQEFSMLEADILREKDQIYNKERFIRDLRSRVSREEINHETQMRETNLSTKISILDPETGKDMSPYEAYKRGIIDRGQYIQLQELECDWEEITTLGPNGEISVLLDKKSGKQYSIDDALRLRRITKEEYQLYRDGKIPISEFALLVAGESKPPPSLSIGSIISKSPVQSPTTLQTQSFFPPGLQKGFGDDASPIAGVYDTTTDTKYNIRTAVTKKLLDPMTAQKLLEAQAATGGIIDLLSRDRLSVHKAIERGLIDRTYMQRLLNAQKAFTGIEDPVTKRRLSVGEAVQKGWMTKDSAFPYLEVQHLTGGLIDPKKTGRIPVLEAAQMGMITGDLANRLQDESSYEKDLIDPITKEKINYKEAMALCQKDSLGSLLLLPAASEGYQPYRSPKLSRFRH", "length": 2158 }, "evidence": [ { "id": "E1B9N6", "url": "https://omabrowser.org/oma/group/E1B9N6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1Q4X8-1", "protein_name": "Envoplakin a", "gene_name": "evpla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFKRNKDSTVKDDSKINKTQVSNLALLIARMQKNADTVEKDVLRAEELLLLDAENEKNNKTLQHQKETADLLGRAEGLLKDLFLDMDKAKKLQHPQAGEIENDVSRLHERWLKDCSLYRELYEPLNEVELQPRINWALVLNQKQKDASKEEYGPTLADLKKQIAAHNILHKEIESYNNQLNPGSTSSQEEYAAIKKQYANLLDNSKWRRHYLNSLYDYMQDCDKEVAYMKEEQNKILKQDWSDQMVDHADVRRQYENFKNNSLLAHESEVNKLQDDGDRLIELKHPAASTVQAQRDTVRNEWQKFLNLCICQETHLDNIEEYKKYQLDADTLSESLSKLGSTVDAKSVNGKTSTEIQMQLQSEERPLQRNEQLLADMRKRSTTIVPLKLRRTPPSKTTTVESLCDWKTPKATLNRGELFNLKSNTDNDNWEVQSSDGTSQKFPGVCFMIPPPDPEAINRVDLLGKELEDLKKRRAALRTLQNNQQSKAPLSQAPVPAPRAEENPKAAVLANRLNQMDKDLGQVEMDTLNCIRSPLNRTDPATDLAKRLQEQEKTTAALQQLEKQRVAAQKEMEPLLSKDLNGPTSSTLLQNLSDAKNKQDSLVALNSLYKKKANASLVLERQLRQMDNTVSGFEKQLSEDGAIPDKPNAIQTRTQEIQGLKRDVAGSQNEMQKLSEDLEALKKLCSSLQQGYQEYCPDIRRQEAEVKNLQSRYSNVINQLSERERLLQEANTKHQDFQNVSQSLSLLLDNLPDNKVSPKDDLSQIQAKQNSQKRVIEDIQRKGDDMNRVVDLSKDLQNVLNEYEVNCDKYKAILDDTTVTNAKRLHTSTLASSVAKQEKDLTKQYAETAAESDQLLKQINFAKGIVTENVEQVNTIQQQQQQQLQQKAFEDTEVLQKELKEEIAKRTNAENTLGTIKSRYLSLKSRRGIERVEEKEILQYYRDPKLQASVDDFQKKIHEEALKRTKTQSEIEVLNRKITSLESELKNTKPKLVTREVTEVERDPQLDVESTNIHESINKLSRELRVKEQEKAQLQTELKMLEQKKQNIKEKVVQKEVVRLEKDPEMLKAVRTFELDISDEGERCKSLKSEISQTKSNINSLERLIPTLEPKVVTKEVKRVEQDPVLIMESKELLNKIEEVRNENKSLMFELNNLQSRHVQIQQMKPRVEVKEIINENFRVAPETEAEMQRLRRELQDNSRQCSDFERQISFVKTEHEALRAQKPKVEYKEVVQEVVKEERSPENVREIQRLSDQVYSLQKAYNNLQNDLIRLRKDRDEWKAEKSKVETKIVTKDVTKYVDDPLQEKEVDRLRRDVREETQRRRTIEEMVFDLQNKYIQLERQKPEEKLVVQEVVRLQKDPRQILDHDRLGRSLDEEVKNRRKLELEVQQLRALIEDKEIAIRSSDEKQKKIQVETELRQIKSRIHELETAPPPIEENIVIEEVLKVERDPKLDKLTNGLRTDMDKESSDIMRLERDIRKLALDIEILQREKSVEKTIYKEVVRVEKDQALEAERSHLRDQFLQEKNVRRDLEDKLHRLQEKLQQQASKKTAMSLEETNLVHDRDKLQREKENLQRELRSLESERQNITISFQQHSRLMSERNQMNRQRSIKMESDGQRLERDILDEKDKIHKRDNIIRELKNSLQKEDSSEMRTKEVNVSTKISILDPNTGKDMSPYDAYRQGFLDRNKYLQLQEMECDWEEITTMAPDDEILVLQDRKSGKQYSIKTALKEGKVTKYQLQQYKDGKMSISEFALLVAGEKKSSSYTPHFNSQLNQQLKEEFPICGVYDVHTDSCVNVRSAMSRKLIDTNTAQKLLEAQAATGGIVDISNGIKYSVHKAADRGLIESSQLQRLLNAQKAFTGVEDPMTKERLSVGEAVQKGWMPKENAMRYMEAQFLTGGLVNPNKAGRVNIVDAVSSKMIDSTMMRELQEEINYAKELTDPITKEKINYKQALARCKIDPLSGLPMFNASSKNV", "length": 1975 }, "evidence": [ { "id": "E1B9N6", "url": "https://omabrowser.org/oma/group/E1B9N6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RW07-1", "protein_name": "Envoplakin", "gene_name": "EVPL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFKGLSKSSQGKGSPKGSPAKGSPKGSPSKHSRAATQELALLISRMQANADQVERDILETQKKLQQDRQHSEQSQALQHRQAVGRSLKEAEVLLKDLFLDVDKARRLKHPQAEEIEKDIKQLHERVTQECAEYRALYEKMVLPADMAPRVDWAQVLEQKQKQVSEGQYGPGMAELEQQIAEHNILQKEIEAYGQQLRTLIGPDADTIRSQYRNLLKAASWRGQSLGSLYTHLQGCTRQLSALAQQQQRILQQDWSDLMADPEGLRREYENFKQHELLSQEQCVNQLEDDGERMVELGHPAVGPIQAHQEALKIEWQNFLNLCICQECHLQHVEGYRRFQEEADSVGQSLAKLSSRLDTQYSPGPGGPPGALTELLRQLEAEEKQLAVAEKTVRDLQLRSQEVAPLPQRRSPPQQPLHVDSICDWDSGEVQLLRGERYTLMDNDDPHTWVVQGPTGETKRAPAACFCLPAPDPEAVARASRLASELQALKQKLTTVQSRLKAGAEEPFRPGQQAPAGSAPADPQAQKLLTQMTRLEEDLGQIERQVLAWARAPLSRATPLEDLEGRIQSHKGTTQRLQSLGAEKEAAQQECEAFLSGQPVGAAALHLPVVLNNVKNKYSDVQVLCGLYREKAKAALGLERQIQDADRVIRGFESALAQEAPIPASPGALQQKVSELQRQRRALLEQQACVLGLHRQLKAAEHTCSALQNNFHEFCQDLPHQQRQVRALTDRYHAVGDQLDLREKMVQDTGLMYQQFKNCRDNLSSWLEQLPRGQVRPSDGPSQIAYKLQAQKRLLQEIQGREQDKAMASRLSQDLQAALQGYELQANTYRCSLEPLQAGSAPTRPRVAPLQESIQAQEKSLTKAYTEAAALQQQQLHQLEFARKILEKKELSEDVPVTHHAQQGSERPAPAGAEAEALRSQLEEERRRVAQVQRELEEQRNQLLELRTQRPLERLEEKEVVECFRDPQLESRLSRLKSQVEAEDRKRAGLQAALEAAAQKLVQLESERKATRPHLLTKEVTHIERDPSLDSQAAQLVGEIQHLRAEDAAVSAQLEALRTELQALERKEASVQEKVVVKEVVKVEKDLEMVRAVQALRRQMQEDAAQRKGAEAAVAKAQARIAELERAISAVEPKVVVKEVKKVEQDPGLLREASRLRGLLEEERKKNGALARELKELHEQHSVAEKQKPRVALQERVHEIFHVDPETEREIARLRAELQDMARKRGGVEEAVGQLLPELAVLRAQKPTVEYKEVTEEVVKHEQSPEVLREIDRLKAQLNELVNGSGRAQEQLIRLQGERDEWRRARAKVETRTVSKEVVRREKDPVLEQEARRLRQEVREAAQKRRATEAVVYELQNKYLLLERRRPEEKVVLQEVVVTQKDPKLREEHSRLSRSLDEQVARRRQLEREVQQLRAAIEEDEALLGFQEDRSKKLAAERELRQLTLRVQELERRPPAVQEKIVMEEVVQLEKDPDLEKSTEALRRALEQEKTRVSELHRECKNLQVQIDVLQKTKSQEKTIYKEVIRVEKDRVLEGERARAWEALNRERAARQSREEGARRLRERIDRAEALERTWSREEAELQQARDQASQECGQLRQELRELEKQKQQQVIDLQEESKLRSQKTESERQRAAQRGQELSQLEAAILREKDQIYEKERTLRDLHAKVGCEELSQETQTRETNLSTKISILEPETGKDLSPYEAYKRGIIDRGQYLQLQELECDWEEITTSGPRGEESVLLDRKSGKQYSIEAALRGRRISKEEYHLYKDGRLPIGEFALLVAGETKPCASLSIGAIISKSRSPPRAPRAPVSSLPASPSGSARTASPSPGSTTQPQTTSAPSRRPWPRTCWTPSPGRSCWRRRRPRGASWTSSAESATPCTRPWRGG", "length": 1886 }, "evidence": [ { "id": "E1B9N6", "url": "https://omabrowser.org/oma/group/E1B9N6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q92817-1", "protein_name": "Envoplakin", "gene_name": "EVPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 2033 }, "evidence": [ { "id": "E1B9N6", "url": "https://omabrowser.org/oma/group/E1B9N6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D952-1", "protein_name": "Envoplakin", "gene_name": "Evpl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFKGLSKGSQGKGSPKGSPAKGSPKGSPNKHNRAATQELALLISRMQANADQVERDILETQKKLQQDRQNGEQNQALQHQQETGRNLKEAEVLLKDLFLDVDKARRLKHPQAEEIEKDIKQLHERVTQECSEYRALYEKMVLPPDVGPRVDWARVLEQKQNLVREGHYGPGMAELEQQVAEHNILQREIEAYGQQLRTLVGPDANTIRNQYRELLKAASWRRQSLGSLYTHLQGCTKQLSALADQQGRILQQDWSDLMPDPAGVRREYEHFKQHELLAQERSINQLEDDADRMVELGHPAIGPIQVHQEALKMEWQNFLNLCICQESQLQRVEDYRRFQEEADSVSQTLAKLSSNLDTKYGFGTGDSSGSPTELLLQLEAEEKQLAIAERAVGDLQQRSQEVAPLPQRRNPSKQPLHVDSICDWDSGEVQLLRGERYTLKDNADPYTWLVQGPGGETKSAPAACLCIPAPDPEAVAKASRLATELQTLKQKLSTEKNRLKAAAVEHLQPGQQAPAGSAPADPQGQTLLSQMTQLDGDLGQIERQVLSWARSPLSQSSSLKDLEGRIHSCEGTAQRLQSLGAEKEAAQQECEAFLSTKPTGSAALQLPVVLNSVKNRYNDVQSLCHLYGEKAKAALGLEKQIQEADRVIQGFEAALALEGPVPEGSGALQERVSELQRQRKELLQQQACVLGLHRQLKATEHACSALQNNFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKIVQDASLTYQQLRNSRDNLSSWLEQLPHHRVQPSDGPSQISYKLQAQKRLIQEILGREQDQATVSRLTRDLQEALQDYELQADTYRCSLEPALAVSAPKRLRVISLQESIQAQEKNLAKAYTEVAAAEQQQLRQLEFAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQPVARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPHLLTKEVTQIERDPGLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNNVALARELQELQEKYRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPVVEYKEVTQEVVRHEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDPVLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIRVEKDPVLEGERARVWEILNRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLSTKICILEPETGNDMSPYEAYKRGVIDRGQYLQLQELECDWEEVTTSSPCGEESVLLDRKSGKQYSIEAALRCRRISKEEYHRYKDGRLPISEFALLVAGETKPSSSLSIGSIISKSPVCSPGPQSTGFFSPGLSFGLTEDSFPIAGIYDTTTDNKCSIKAAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAVERGLIENTSTQRLLNAQKAFTGIEDPVTRKRLSVGEAIQKGWMPQESVLPHLLVQHLTGGLIDPKRTGRIPVPQAVLCGMISEDLGQLLQDESGYEKDLTDPITKERLSYKEAMGRCRKDPLSGLLLLPAMLEGYRCYRAASPTLPRSCVR", "length": 2035 }, "evidence": [ { "id": "E1B9N6", "url": "https://omabrowser.org/oma/group/E1B9N6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1B9N6", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1B9N6", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1B9N6", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" } ], "pmid": "" }, { "name": "intermediate filament cytoskeleton", "id": "GO:0045111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045111", "evidence": [ { "database": "UniProtKB", "id": "E1B9N6", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" } ], "pmid": "" }, { "name": "cornified envelope", "id": "GO:0001533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001533", "evidence": [ { "database": "UniProtKB", "id": "E1B9N6", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "E1B9N6", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "keratinization", "id": "GO:0031424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424", "evidence": [ { "database": "UniProtKB", "id": "E1B9N6", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "E1B9N6", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" } ], "pmid": "" }, { "name": "intermediate filament cytoskeleton organization", "id": "GO:0045104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045104", "evidence": [ { "database": "UniProtKB", "id": "E1B9N6", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "E1B9N6", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1219, "end_pos": 1221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1276, "end_pos": 1278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1665, "end_pos": 1667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 751, "end_pos": 753, "annotation": "n_glycosylation_sequon" }, { "start_pos": 853, "end_pos": 855, "annotation": "n_glycosylation_sequon" }, { "start_pos": 965, "end_pos": 967, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B9N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" }, { "id": "PF17902", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17902" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Desmoplakin SH3", "eco_id": "ECO_0000259", "start_pos": 404, "end_pos": 468, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1B9N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" }, { "id": "PF26346", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26346" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Periplakin-like plectin repeat", "eco_id": "ECO_0000259", "start_pos": 960, "end_pos": 1124, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1B9N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N6" }, { "id": "PF23160", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23160" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Periplakin/Envoplakin N-terminal", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 138, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1219, "end_pos": 1221 }, { "start_pos": 1276, "end_pos": 1278 }, { "start_pos": 1665, "end_pos": 1667 }, { "start_pos": 353, "end_pos": 355 }, { "start_pos": 751, "end_pos": 753 }, { "start_pos": 853, "end_pos": 855 }, { "start_pos": 965, "end_pos": 967 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1B9P2-1", "uniprot_ac": "E1B9P2", "uniprot_id": "E1B9P2_BOVIN", "mass": { "chemical_mass": 40033.0, "monoisotopic_mass": 40033.0 }, "refseq": { "ac": "NP_001179232", "name": "cannabinoid receptor 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179232" }, "gene_names": [ { "name": "CNR2", "type": "recommended", "evidence": [ { "id": "E1B9P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9P2" } ] }, { "name": "CNR2", "type": "synonym", "evidence": [ { "id": "NP_001179232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179232" } ] } ], "protein_names": [ { "name": "Cannabinoid receptor 2", "type": "synonym", "evidence": [ { "id": "E1B9P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9P2/entry#names_and_taxonomy" } ] }, { "name": "cannabinoid receptor 2 (macrophage)", "type": "synonym", "evidence": [ { "id": "NP_001179232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179232" } ] }, { "name": "cannabinoid receptor 2", "type": "synonym", "evidence": [ { "id": "NP_001179232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179232" } ] } ], "function": [ { "annotation": "Histological analyses revealed numerous endocrinal cell clusters or islets which were distributed among exocrine adenomeri in connectival tissue. 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"IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RHHIQSF", "url": "https://omabrowser.org/oma/group/RHHIQSF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B9Q2", "url": "https://www.orthodb.org/?gene=E1B9Q2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45646", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45646", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45646:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45646:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005203757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005203757", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1B9Q2", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9Q2-1", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPHPRRYHSSERGSRGSYHEHYRSRKHKRRRSRSWSSSSDRTRRRRREDSYHVRSRSYDDRSSDRRAYDRRYCGSYRRNDYSRDRGEAYYDTDYRHSYEYHRENSSYRSQRSSRRKHRRRRRRSRTFSRSSSQHSSRRAKSVEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNAKLWDSSRDISR", "length": 499, "header": "tr|E1B9Q2-1|E1B9Q2_BOVIN Isoform 1 of dual-specificity kinase OS=Bos taurus OX=9913 GN=CLK2 PE=3 SV=2 CANONICAL=E1B9Q2-1" }, "isoforms": [ { "isoform_ac": "E1B9Q2-1", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2/entry#E1B9Q2-1", "sequence": { "sequence": "MPHPRRYHSSERGSRGSYHEHYRSRKHKRRRSRSWSSSSDRTRRRRREDSYHVRSRSYDDRSSDRRAYDRRYCGSYRRNDYSRDRGEAYYDTDYRHSYEYHRENSSYRSQRSSRRKHRRRRRRSRTFSRSSSQHSSRRAKSVEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNAKLWDSSRDISR", "length": 499, "header": "tr|E1B9Q2-1|E1B9Q2_BOVIN Isoform 1 of dual-specificity kinase OS=Bos taurus OX=9913 GN=CLK2 PE=3 SV=2 CANONICAL=E1B9Q2-1" }, "locus": { "chromosome": "3", "start_pos": 15376241, "end_pos": 15369588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019139.8", "url": "https://www.ensembl.org/id/ENSBTAT00000019139.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019139.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019139.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M5A7-1", "protein_name": "dual-specificity kinase", "gene_name": "Clk2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPHPRRYHSSERGSRGSYHEHYRSRKHKRRRSHSWSSSSDRTRRRRREDSYHVRSRSSYDDHSSDRRVYDRRYCGSYRRNDYSRDRGDAYYDTDFRHSYECHRENSSYRSQRSSRRKHRRRRRRSRTFSRSSSQHSSRRAKSVEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNNLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTDVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGHLDWDGNTSAGRYVRENCKPLRRYLTSEAEDHHQLFDLIESMLEYEPAKRLTLGEALQHPFFACLRTEPPNTKLWDSSRDISR", "length": 500 }, "evidence": [ { "id": "E1B9Q2", "url": "https://omabrowser.org/oma/group/E1B9Q2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O35491-1", "protein_name": "Dual specificity protein kinase CLK2", "gene_name": "Clk2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPHPRRYHSSERGSRGSYHEHYQSRKHKRRRSRSWSSSSDRTRRRRREDSYHVRSRSSYDDHSSDRRLYDRRYCGSYRRNDYSRDRGEAYYDTDFRQSYEYHRENSSYRSQRSSRRKHRRRRRRSRTFSRSSSHSSRRAKSVEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGTQVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEDHHQLFDLIENMLEYEPAKRLTLGEALQHPFFACLRTEPPNTKLWDSSRDISR", "length": 499 }, "evidence": [ { "id": "E1B9Q2", "url": "https://omabrowser.org/oma/group/E1B9Q2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49760-1", "protein_name": "Dual specificity protein kinase CLK2", "gene_name": "CLK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPHPRRYHSSERGSRGSYREHYRSRKHKRRRSRSWSSSSDRTRRRRREDSYHVRSRSSYDDRSSDRRVYDRRYCGSYRRNDYSRDRGDAYYDTDYRHSYEYQRENSSYRSQRSSRRKHRRRRRRSRTFSRSSSQHSSRRAKSVEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWDSSRDISR", "length": 499 }, "evidence": [ { "id": "E1B9Q2", "url": "https://omabrowser.org/oma/group/E1B9Q2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51566-1", "protein_name": "Serine/threonine-protein kinase AFC1", "gene_name": "AFC1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQSSVYRDKASSIAMILETQRNVEFPHRIVDKRPRKRPRLTWDAAPPLLPPPPPPTVFQPPLYYGPEFASGLVPNFVYPNMFYNGLPRQGSPPWRPDDKDGHYVFVVGDTLTPRYQILSKMGEGTFGQVLECFDNKNKEVVAIKVIRSINKYREAAMIEIDVLQRLTRHDVGGSRCVQIRNWFDYRNHICIVFEKLGPSLYDFLRKNSYRSFPIDLVRELGRQLLESVAYMHDLRLIHTDLKPENILLVSSEYIKIPDYKFLSRPTKDGSYFKNLPKSSAIKLIDFGSTTFEHQDHNYIVSTRHYRAPEVILGVGWNYPCDLWSIGCILVELCSGEALFQTHENLEHLAMMERVLGPLPPHMVLRADRRSEKYFRRGAKLDWPEGATSRDSLKAVWKLPRLPNLIMQHVDHSAGDLIDLLQGLLRYDPTERFKAREALNHPFFTRSREQSIPPFNPNPHPFLYNQKN", "length": 467 }, "evidence": [ { "id": "E1B9Q2", "url": "https://omabrowser.org/oma/group/E1B9Q2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q2", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q2", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q2", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q2", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ], "pmid": "" }, { "name": "protein serine/threonine/tyrosine kinase activity", "id": "GO:0004712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004712", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q2", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q2", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q2", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q2", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q2", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MWN2-1", "A0AAF6DMB3-1", "E1BI01-1", "A0AAA9TQL1-1", "F1MQH2-1", "F1N781-1", "F6QXU6-1", "A0A3Q1MKW9-1", "A0A3Q1M0U5-1", "F6S1J8-1", "A5D791-1", "F1N664-1", "E1BMP9-1", "F1MS00-1", "P43481-1", "A0A3Q1LR28-1", "A0A3Q1LVP1-1", "Q06807-1", "A0AAA9TD48-1", "Q5E9X2-1", "Q05688-1", "Q17R13-1", "E1BG90-1", "Q0VBZ0-1", "F1N758-1", "A0A3Q1LTC6-1", "A0A3Q1LNU2-1", "F1N1Q0-1", "A0A3Q1MHB0-1", "A0AAA9SN20-1", "A0AAA9TMY2-1", "A0A3Q1LI98-1", "E1BJ31-1", "A0A3Q1LRR9-1", "F1MX49-1", "A0A3Q1MHG9-1", "A0JNB0-1", "E1BER5-1", "E1BIM8-1", "E1BNE0-1", "A0A3Q1LT44-1", "A0A3Q1MJG0-1", "F1MII5-1", "F1N0D3-1", "F1N261-1", "F1N759-1", "F1N780-1", "F1MC14-1", "F1N3R6-1", "A0ABI0P1V8-1", "A0A3Q1LUE0-1", "F1MFH7-1", "F1MNW2-1", "A0AAA9SPC9-1", "F1N381-1", "F1MS29-1", "G1K218-1", "Q4TVR5-1", "A0AAA9SXH6-1", "E1BJS9-1", "A0AAA9SBR4-1", "F1MKR1-1", "F1MN51-1", "E1BCZ6-1", "E1BEL4-1", "F1MCX4-1", "F1N6J0-1", "Q3SZJ2-1", "Q769I5-1", "Z4YHD9-1", "Q06805-1", "Q3SX21-1", "A0A3Q1MAM7-1", "E1BPB5-1", "A0A3Q1MF99-1", "A0AAA9SA57-1", "A0AAA9TAT1-1", "A0AAA9THG2-1", "F1MC23-1", "A0AAA9SVL9-1", "F1MRU0-1", "A0AAA9T042-1", "E1BKP7-1", "E1BNA8-1", "F1ML02-1", "E1BPI3-1", "A0AAA9SW95-1", "G3X680-1", "A0AAA9TRY4-1", "A0A3Q1MEZ6-1", "E1B9H4-1", "E1B6X6-1", "E1B9Q2-1", "E1BPP1-1", "F1N6H6-1", "A0ABI0NRQ5-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": 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"id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": 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"2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SA57", "gene_name": "ABL2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] } ] }, { "uniprot_ac": "A0AAA9SBR4", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SN20", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SPC9", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVL9", "gene_name": "FLT4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SW95", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SXH6", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TAT1", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9THG2", "gene_name": "EPHB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TMY2", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TQL1", "gene_name": "DDR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] } ] }, { "uniprot_ac": "A0AAA9TRY4", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMB3", "gene_name": "DDR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P1V8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A0JNB0", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B6X6", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9H4", "gene_name": "PKDCC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BCZ6", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEL4", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] } ] }, { "uniprot_ac": "E1BER5", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BIM8", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BJS9", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKP7", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BMP9", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNA8", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] } ] }, { "uniprot_ac": "E1BNE0", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPI3", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC14", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] } ] }, { "uniprot_ac": "F1MC23", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MCX4", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFH7", "gene_name": "EPHA1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MII5", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKR1", "gene_name": "EPHA8", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1ML02", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MN51", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MNW2", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MQH2", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] } ] }, { "uniprot_ac": "F1MRU0", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] } ] }, { "uniprot_ac": "F1MS00", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] } ] }, { "uniprot_ac": "F1MS29", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWN2", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MX49", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N0D3", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] } ] }, { "uniprot_ac": "F1N1Q0", "gene_name": "SRMS", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] } ] }, { "uniprot_ac": "F1N261", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N381", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] } ] }, { "uniprot_ac": "F1N3R6", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F1N6H6", "gene_name": "EPHA10", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] } ] }, { "uniprot_ac": "F1N6J0", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] } ] }, { "uniprot_ac": "F1N758", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] } ] }, { "uniprot_ac": "F1N759", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] } ] }, { "uniprot_ac": "F1N780", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] } ] }, { "uniprot_ac": "F1N781", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QXU6", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "F6S1J8", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] } ] }, { "uniprot_ac": "G1K218", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G3X680", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P43481", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q05688", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05688" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q05688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05688" } ] } ] }, { "uniprot_ac": "Q06805", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q06805", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06805" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q06805", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06805" } ] } ] }, { "uniprot_ac": "Q06807", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q06807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06807" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q06807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06807" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VBZ0", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", 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"MSLSSGASGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRNKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGSLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCAEKDPGVLQPVPLGGRGGQYDGSAGVDPGAVEPLGSIAIEPGAALNPLGAKPEPEEGENECRPLKKVKSEKMESPVSTPAVLPLHLLVPVVSNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSSSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPALHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTTTVVQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKEKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLDSTTPTQPMTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDPEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKKDEEPETIEGKVKNDVCEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNSAYRQQYEEQQKRQSLEQQQRGLDKKAEMGLKEREAALKEDWKQKPSIPPTLTKAPSLTDLVKSGPSKAKEPGADPAKSVIIPKLDDSSKLPSQAPEGLKVKLSEASHLGKETSEAKTGADCGRQAEVDPILWYRQEAEPRMWTYVYPAKYSDIKPEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEEPRLGGKEPRPSVHVPVSSPLTQHQPYIPYMHGYSYSQSYDPSHPSYRGMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASPSVSCKSSSESKALDILQQHASHYKSKSPTISDKTSQERDRGGCGVVGGGGSCSSVGGAGGGERSVDRPRTSPSQRLMSTHHHHHHLGYSLLPAQYNLPYAAGLSSTAIVASQQGSTPSLYPPPRR", "length": 1411, "header": "tr|E1B9Q8-1|E1B9Q8_BOVIN Isoform 1 of Zinc finger protein 609 OS=Bos taurus OX=9913 GN=ZNF609 PE=4 SV=2 CANONICAL=E1B9Q8-1" }, "locus": { "chromosome": "10", "start_pos": 45556175, "end_pos": 45385276, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020995.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020995.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020995.5", "url": "https://www.ensembl.org/id/ENSBTAP00000020995.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 256, "start_aa": "Thr", "end_pos": 256, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr256", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:510374", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510374", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZWE7-1", "protein_name": "Zinc finger protein 609", "gene_name": "ZNF609", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSLSSGASGGKGIDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGLPAPNAVATLPDNIKFVSPVPGPQGKEGKSKSKRSKSGKDSGKPAPGSSLFAAGEGAGGKKEAQGRSGDGANSGGLGPAVTPKGSEKSAKVSRSVAGSKKDKEGGSSKSKKERSEGAGAPTEKEPGVLQPLALAVRVGQYDGGQGTEPAAATEQLGSIAIDTGAALNPLGVKSELEDGEGECRQLKKVKSEKMESPVSTPAVLPLHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTQHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETAATSDSKGTSNSSKTRAGANSKGRRGSQNSSDHRTPPSGTAEDVKASPSSVTKRKSKPLSDMELNSSSEDSKGSKRIRTNSMGSAAVPPTAVKVEPTVLDRNCPSPILIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKLEADVDSEYGEEPSLHTDVGSCNGATVSQKGSLSPARSATPKVRLMEPHSPSPSSKFSAKVPCKKKLAGEGDTDPGALSNDGSEDGPSVADETSNDGFDALEKRCVDKDKSKKASGAKQEKMPSKSLKSARPIAPAVPPQPIYTFQTATLTAASPGSSAGLTTTVVQTMPSSPQLKPIQPKPTVMGEPFAVNPALTPSKEKKKKDKKKKEPKEVENPLTPGKVCRAEEGKSPFRGETSDLGTKSEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGASRLENANPAQPMTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKLESVKTKDPEQLVKDGAKKALFPPQPQSKESPYYQGFETYYSPGYPQASPGPLNPSSQAAAETQALKLKKDEEQENPEVKVKSEGVEEKKAELGSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYNEQGYHAHLLSTNPAYRQQYEEQQKQRQSLEQQQQRGLEKKAELGMKEREALKEEWKQKPPMPPTLTKAPSLTDLVKSGLSKAKEQGGADMAKSVIIPKLEDSSKLPGSQVAEGLKVKLSEAGHLGKETVETKGGSECGRQAEVDPVLWYRQEAEPRMWTYVYPAKYSDIKTEDERWKEERDRKLKEERNRSKEVVSKEDGKESTSSECKLTPTEEARMVGKDPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRAMPTVMMQNYPGSYLPSSYSFSPYGSKASGSDDSDKSRASPSVSCKSSSESKALDILQQHASHYKSKSPTISEKTTQERDRGGCGVVGGSGSCSSIGGAGGGERSAERPRTSPSQRLLSTHHHHHHLGYSLLPAQYNLPYATGLSSTAIVASQQGSAPSLYPPPRRT", "length": 1416 }, "evidence": [ { "id": "E1B9Q8", "url": "https://omabrowser.org/oma/group/E1B9Q8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ACN4-1", "protein_name": "Zinc finger protein 609", "gene_name": "Zfp609", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSGACGGKAVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFSPSEGAANKKEVQGRSGDGTSAGGLVAAVAPKGSEKAAKASRSVAGSKKEKESSSSKGKKERSEGAGTCSEKDPGVLQPVPLGGRGSQYDGNAGMDTGGVEPLGSIASEPGAALNPLGTKPEPEEGENECRPLKKVKSEKMESPVSTPAVLPLHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVSETATASDSKGTSSNSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTIVDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPTLHTDLSSCNGAPVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDPGASSNDGSDDGPSVVDETSNDGFDSVERKCVEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTTTVVQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKDSSKELESPLTPGKVCRAEEGKSPFRESAGDGVKMEGLLNGSSESHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLDSTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSAKSKDPEQLVKEGAKKTLFPPQPQSKDSAYYQGFESYYSPGYAQSSPGALPSSSQAGMEGQALKTKKDEEPENIEGKVKNDVCEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSEQSYHTHLLSTNTAYRQQYEEQQKRQGVEQPQRGLDKKTEMGLKEREASLKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGTDPAKSVIIPKLDDSSKLPSQPPEGLKGKLGEASHLGKEASEAKTGTECGRQAEVDPILWYRQETEPRMWTYVYPAKYSDIKSEDDRWKEERDRKLKEDRSRSKDSVPKEDGKESTSSDCKLPTSEEPRLGSKEPRPGVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRGMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASPSVSCKASSESKALDILQQHASHYKSKSPTISDKNSQERDRGGCGVVGGGGSCGSVGGAGGADRSADRPRTSPSQRLMSTHHHHHHLGYSLLPAQYNLPYAAGLSSTAIVASQQGSTPSLYPPPRR", "length": 1411 }, "evidence": [ { "id": "E1B9Q8", "url": "https://omabrowser.org/oma/group/E1B9Q8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S0A9-1", "protein_name": "Zinc finger protein 609", "gene_name": "ZNF609", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLSSGASGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRNKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGSLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDPGVLQPVPLGGRGGQYDGSAGVDAGAVEPLGSIAIEPGAALNPLGAKPEPEEGENECRPLKKVKSEKMESPVSTPAVLPLHLLVPVVSNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETAAASDNKGTSSSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPPPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPTLHTDLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGDGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTTTVVQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGVKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLDSTTPTQPMTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDPEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPNYAQSSPGALNPSSQAGVESQALKAKKDEEPESMEGKVKNDACEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGLDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPSQAPEGLKVKLSEASHLGKEASEAKAGPECGRQAEVDPILWYRQEAEPRMWTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEESRLGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYGQSYDPNHPSYRGMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARSSPSVSCKSSSESKALDILQQHASHYKSKSPTISDKNSQERDRGGCGVVGGGGSCSSVGGAGGGERSVDRPRTSPSQRLMSTHHHHHHLGYSLLPAQYNLPYAAGLSSTAIVASQQGSTPSLYPPPRR", "length": 1411 }, "evidence": [ { "id": "E1B9Q8", "url": "https://omabrowser.org/oma/group/E1B9Q8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15014-1", "protein_name": "Zinc finger protein 609", "gene_name": "ZNF609", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLSSGASGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDPGVLQPVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECRLLKKVKSEKMESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMDPILWYRQEAEPRMWTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEESRLGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRSMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASPSVTCKSSSESKALDILQQHASHYKSKSPTISDKTSQERDRGGCGVVGGGGSCSSVGGASGGERSVDRPRTSPSQRLMSTHHHHHHLGYSLLPAQYNLPYAAGLSSTAIVASQQGSTPSLYPPPRR", "length": 1411 }, "evidence": [ { "id": "E1B9Q8", "url": "https://omabrowser.org/oma/group/E1B9Q8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BZ47-1", "protein_name": "Zinc finger protein 609", "gene_name": "Znf609", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLSSGACGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDASKPTPGTSLFSPSEGAASKKEVQGRAGDGASAGGLVAAVAPKGSEKAAKASRSVAGSKKEKENSSSKGKKERSEGVGTCSEKDPGVLQPVPLGGRGSQYDGSAGMDTGTVEPLGSIAIEPGAALNPLGTKPEPEEGENECRPLKKVKSEKMESPVSTPAVLPLHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPSSNTPVSEAAAASDSKGTSSSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKSKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTLVDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPALHADLSCNGAPVPQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDPGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKSEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTTTVVQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKDSSKELESPLTPGKVCRAEEGKSPFRDAAGDGIKVESLLNGSSESHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLDSTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSAKSKDPEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPGYAQSSPGTLTSSSQAGMEGQPLKTKKDEEPESVEGKVKNDVCEEKKPELSNSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHSHLLSTNTAYRQQYEEQQKRQSLEQQQQQQRGLDKKTEMGLKEREASLKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGTDPAKSVIIPKLDDSSKLPSQPPEGLKGKLGEASHLGKEASEAKTGTECGRQAEVDPILWYRQETESRMWTYVYPAKYSDIKSEDDRWKEERDRKLKEDRSRSKDSVPKEDGKESTSSDCKLPPSEESRLGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRGMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASPSVSCKASSESKALDILQQHASHYKSKSPTISDKNSQERDRGGCGVVGGGGSCGSVAGAGGTDRSADRPRTSPSQRLMSTHHHHHHLGYSLLPAQYNLPYAAGLSSTAIVASQQGSTPSLYPPPRR", "length": 1413 }, "evidence": [ { "id": "E1B9Q8", "url": "https://omabrowser.org/oma/group/E1B9Q8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q8", "url": "https://www.uniprot.org/uniprotkb/E1B9Q8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q8", "url": "https://www.uniprot.org/uniprotkb/E1B9Q8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q8", "url": "https://www.uniprot.org/uniprotkb/E1B9Q8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q8", "url": "https://www.uniprot.org/uniprotkb/E1B9Q8" } ], "pmid": "" }, { "name": "regulation of myoblast proliferation", "id": "GO:2000291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000291", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q8", "url": "https://www.uniprot.org/uniprotkb/E1B9Q8" } ], "pmid": "" }, { "name": "positive regulation of neuron migration", "id": "GO:2001224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001224", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q8", "url": "https://www.uniprot.org/uniprotkb/E1B9Q8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q8", "url": "https://www.uniprot.org/uniprotkb/E1B9Q8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q8", "url": "https://www.uniprot.org/uniprotkb/E1B9Q8" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "E1B9Q8", "url": "https://www.uniprot.org/uniprotkb/E1B9Q8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1B9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 495, "end_pos": 525, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 103, 256 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 335, "end_pos": 337 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 775, "end_pos": 777 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"length": 4493, "header": "tr|E1B9R5-1|E1B9R5_BOVIN Isoform 1 of Dynein axonemal heavy chain 8 OS=Bos taurus OX=9913 GN=DNAH8 PE=1 SV=4 CANONICAL=E1B9R5-1" }, "isoforms": [ { "isoform_ac": "E1B9R5-1", "url": "https://www.uniprot.org/uniprotkb/E1B9R5/entry#E1B9R5-1", "sequence": { "sequence": "MMRLYVDNAAPEKLKGQCVFFVRCRNDIPINTKNIQEEVLFTVLDASEGLLVGIRNMLANIFLPAILATNSWGALNQSQQGESEKQIFIETINRYLSFLDGARISIEGTVKLKKIDSVDFSKLHTFEDVTLAASNSETVRQLEDVLMIWYKQIEQVLIESEQMRKEADDSGPLTELEHWKRMSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNYDLVSMAHGIQNLINAIRMIHSVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGTNHVWDQETPVVLKKIQDCIFLFKEYQASFHKTRKQILESSGEKSFEVSEMYIFGKFEAFCKRLEKITEMITVVQTYSTLNNSTIEGIDILAIKFKNIYQGVKKKQYDILDPRRTEFDTDFLDFMTKINALEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNIPCLQLEINHTIERILQYYVAELEATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSEILSSAEGKAVIRQYNKISYVLVEFEVVYHTAWIREISQLQYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKGDKLYLQGLLQHYDDLCQEVPPVFVNLMTPKMKKVEAVLRQGLTILTWSSLTLESFFQEVDSVLGMFNQLLKKINDLCEMHIDAVLKEIAKTLLISLPETGATKVEDMLTLNETYTKEWAEVLNHKSKHVEEAVKELISIFETIYEVKYSGKGARHLPELRKHVVFGSEGEDVESADYDANIVPEADVKDDKEDEFKKECKEVYAFFSHQLLDSLQKATRLSLDTMKRRIFVASPYGRKRSEDVISFLKSEVHLAIPNVVMVPSLDDIQQAINRMIQLTLEVSRGVAHWGQQSRHIKRVISSTSRTTMDVAHSSPGKQLKKEERSFEEMIPARKLKNFYPGVAEHKDISKLVLLLSSSVNSLRKAVHEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTEIRSEILHYATFEQEIDELKPIIVVGALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSDMIAFINEYLKKLSRPIRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSFNKLQSKAVSVQDELVQVQPKFKSNLLESVEVFREDVMNFAEAYETEGPMVPNIPPQEASNRLQIFQANFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMGNISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKNKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVISCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGEKIILDSPVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLNHFPAQVGLLGIQMLWTHDSEEALNNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIHVHQRDIFDDLVKMHIRSVTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSTVMRGLRDMNLSKLIDEDEPLFLSLINDLFPGLQLDSNSYVELQAAVTNQVQLEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTMVITILMKALTECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRTTQENNVFLTLYDKIFEDAYTFMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGISCVEHLHKLFVFALMWSLGALLELESRDKLEAFMRSHESKLDLPEIPKGLTQTMYEFYVTDYGDWEHWNKKLQPYYYPTDSVPEYSSILVPNVDNVRTNFLIDTIAKQHKAVLLTGEQGTAKTVMIKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRMGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGVIGCGYFDACRRFKPEICEMILNLVSASRMLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKADECASVHVLLSLFKHECNRVIADRFITPDDEQWFNTQLVRSVEENVSPDVGSYILPEPYFVDFLREMPEPTGDEPEDTAFEVPKVYELVPSFEFLSEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVSNLTDDLKGLYKVAGADGKGITFIFTDNEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALVAVASYFVSGYSIVCSSDTKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYTEKVKYINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASVKADEVLAEVTVSAQASAKVKNEVQEVKDKAQKIVDEIDSEKVIAETKLEAARPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKPCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMATFYGVNREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADMCRKKMQAASTLIDGLSGEKVRWTQQSKEFRAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKEQWEIELKARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIREELDPALDNVLEKNFIKSGTTFKVKVGDKECDVMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELESERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKLTAAEVSEKLHVAAETEVKINTAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKPFRWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLDTCRKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMGSDPTIQIDALAKKLKLECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFMEELLETLTITETIDDTFRVWITTEPHIRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLDISNLPMWKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEPSFCFYTGYKIPVCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPDYVPHEVKARLIKMGHLNSMNIFLRQEIDRMQKVISILRSSLNDLKLAIEGTIIMSENLRDALDNMYDARIPQIWKRVSWDSSTLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDSVTIHNEVLRQTKEEVTSPPAEGVYIYGLYMDGAAWDRRNGKLTESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDLTFITVVYLRTVLSPDHWILRGVALLCDIK", "length": 4493, "header": "tr|E1B9R5-1|E1B9R5_BOVIN Isoform 1 of Dynein axonemal heavy chain 8 OS=Bos taurus OX=9913 GN=DNAH8 PE=1 SV=4 CANONICAL=E1B9R5-1" }, "locus": { "chromosome": "23", "start_pos": 12888734, "end_pos": 12566464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018689.8", "url": "https://www.ensembl.org/id/ENSBTAT00000018689.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018689.7", "url": "https://www.ensembl.org/id/ENSBTAP00000018689.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3041, "start_aa": "Thr", "end_pos": 3041, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3041", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Structural diversity of axonemes across mammalian motile cilia.", "journal": "Nature", "date": "2025", "authors": "Leung Miguel Ricardo, Sun Chen, Zeng Jianwei, Anderson Jacob R, Niu Qingwei, Huang Wei, Noteborn Willem E M, Brown Alan, Zeev-Ben-Mordehai Tzviya, Zhang Rui", "evidence": [ { "database": "UniProtKB", "id": "E1B9R5", "url": "https://www.uniprot.org/uniprotkb/E1B9R5" } ], "reference": [ { "type": "PubMed", "id": "39743588", "url": "https://glygen.org/publication/PubMed/39743588" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1B9R5", "url": "https://www.uniprot.org/uniprotkb/E1B9R5" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "E1B9R5", "url": "https://www.uniprot.org/uniprotkb/E1B9R5" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "E1B9R5", "url": "https://www.uniprot.org/uniprotkb/E1B9R5" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "E1B9R5", "url": "https://www.uniprot.org/uniprotkb/E1B9R5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "E1B9R5", "url": "https://www.uniprot.org/uniprotkb/E1B9R5" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "E1B9R5", "url": "https://www.uniprot.org/uniprotkb/E1B9R5" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "E1B9R5", "url": "https://www.uniprot.org/uniprotkb/E1B9R5" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "E1B9R5", "url": "https://www.uniprot.org/uniprotkb/E1B9R5" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "E1B9R5", "url": "https://www.uniprot.org/uniprotkb/E1B9R5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "E1B9R5", "url": "https://www.uniprot.org/uniprotkb/E1B9R5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1294, "end_pos": 1296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1423, "end_pos": 1425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1428, "end_pos": 1430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1874, "end_pos": 1876, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2058, "end_pos": 2060, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2225, "end_pos": 2227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2253, "end_pos": 2255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, 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] }, { "id": "PTHR24333:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24333:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193177", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193177", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1B9T6", "url": "https://www.uniprot.org/uniprotkb/E1B9T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9T6-1", "url": "https://www.uniprot.org/uniprotkb/E1B9T6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 327 }, "evidence": [ { "id": "E1B9T6", "url": "https://omabrowser.org/oma/group/E1B9T6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P63156-1", "protein_name": "BarH-like 1 homeobox protein", "gene_name": "Barhl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETSTSRPGAASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAGEDFRDKLDKSVSSASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLPGVLPRAAQPR", "length": 327 }, "evidence": [ { "id": "E1B9T6", "url": "https://omabrowser.org/oma/group/E1B9T6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P63157-1", "protein_name": "BarH-like 1 homeobox protein", "gene_name": "Barhl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETSTSRPGAASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAGEDFRDKLDKSVSSASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLPGVLPRAAQPR", "length": 327 }, "evidence": [ { "id": "E1B9T6", "url": "https://omabrowser.org/oma/group/E1B9T6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZE3-1", "protein_name": "BarH-like 1 homeobox protein", "gene_name": "BARHL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETGTPRPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLAGVLPRAAQPR", "length": 327 }, "evidence": [ { "id": "E1B9T6", "url": "https://omabrowser.org/oma/group/E1B9T6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1B9T6", "url": "https://www.uniprot.org/uniprotkb/E1B9T6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1B9T6", "url": "https://www.uniprot.org/uniprotkb/E1B9T6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1B9T6", "url": "https://www.uniprot.org/uniprotkb/E1B9T6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "E1B9T6", "url": "https://www.uniprot.org/uniprotkb/E1B9T6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1B9T6", "url": 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"database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LBA8-1", "protein_name": "Olfactory receptor 10J5", "gene_name": "LOC100773116", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQRKNFTEVTEFIFLGFSSFGHHQMTLFAVFLTIYILTLAGNITIVTIACMDHHLHTPMYFFLSMLASSETVYTLVIVPRMLSSLIFHNLAISLAGCATQMFFFVTLATNNCFLLTAMGYDRYVAICDPLRYMVIMSKGMCAWLVCGSLGTGLVMAVLHVPAMFNLPFCGTVVEHFFCDIYPVMKLSCVDTTLNEIINYGVSSFVILVPIGLIFISYVLIISSILKIASTEGRKKAFATCASHLTVVIVHYGCASIAYLKPKSESSVEKDLLLSVTYTIITPLLNPVVYSLRNKEVKDALCRAVGRNTS", "length": 309 }, "evidence": [ { "id": "E1B9X6", "url": "https://omabrowser.org/oma/group/E1B9X6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q62007-1", "protein_name": "Olfactory receptor 10J5", "gene_name": "Or10j5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRNNFTEVIEFVFLGFSSFGKHQITLFVVFLTIYILTLAGNIIIVTITHIDHHLHTPMYFFLSMLASSETVYTLVIVPRMLSSLIFYNLPISLAGCATQMFFFVTLATNNCFLLTAMGYDRYVAICNPLRYTIIMSKGMCALLVCGSLGTGLVMAVLHVPAMFHLPFCGTVVEHFFCDIYPVMKLSCVDTTVNEIINYGVSSFVILVPIGLIFISYVLIVSSILKIVSTEGQKKAFATCASHLTVVIVHYGCASIAYLKPKSESSVEKDLLLSVTYTIITPLLNPVVYSLRNKEVKDALCRAVGRNTS", "length": 309 }, "evidence": [ { "id": "E1B9X6", "url": "https://omabrowser.org/oma/group/E1B9X6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NHC4-1", "protein_name": "Olfactory receptor 10J5", "gene_name": "OR10J5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKRKNFTEVSEFIFLGFSSFGKHQITLFVVFLTVYILTLVANIIIVTIICIDHHLHTPMYFFLSMLASSETVYTLVIVPRMLLSLIFHNQPISLAGCATQMFFFVILATNNCFLLTAMGYDRYVAICRPLRYTVIMSKGLCAQLVCGSFGIGLTMAVLHVTAMFNLPFCGTVVDHFFCDIYPVMKLSCIDTTINEIINYGVSSFVIFVPIGLIFISYVLVISSILQIASAEGRKKTFATCVSHLTVVIVHCGCASIAYLKPKSESSIEKDLVLSVTYTIITPLLNPVVYSLRNKEVKDALCRVVGRNIS", "length": 309 }, 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9X9/entry#names_and_taxonomy" } ] }, { "name": "PR domain zinc finger protein 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059747527", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059747527" } ] }, { "name": "PR domain-containing protein 12", "type": "synonym", "evidence": [ { "id": "E1B9X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9X9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transcriptional regulator necessary for the development of nociceptive neurons, playing a key role in determining the nociceptive lineage from neural crest cell progenitors. Initiates neurogenesis and activates downstream pro-neuronal transcription factors, such as NEUROD1, BRN3A, and ISL1, specifically within nociceptive neurons, while repressing non-nociceptor cell fates. Essential for the proper function of nociceptors in adults, influencing both their excitability and their gene expression, thereby impacting how these neurons respond to various pain stimuli.", "evidence": [ { "database": "UniProtKB", "id": "E1B9X9", "url": "https://www.uniprot.org/uniprotkb/E1B9X9#function" }, { "database": "UniProtKB", "id": "ARBA00093312", "url": "https://www.uniprot.org/uniprotkb/ARBA00093312#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1B9X9", "url": "https://www.uniprot.org/uniprotkb/E1B9X9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRDM12", "url": "https://www.uniprot.org/uniprotkb/E1B9X9", "locus": { "chromosome": "11", "start_pos": 100967191, "end_pos": 100949928, "strand": "-", "evidence": [ { "database": 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"https://www.ebi.ac.uk/interpro/entry/IPR026173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:535545", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535545", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYATVIT", "url": "https://omabrowser.org/oma/group/HYATVIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21963:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21963:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193803", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193803", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BA36", "url": "https://www.uniprot.org/uniprotkb/E1BA36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BA36-1", "url": "https://www.uniprot.org/uniprotkb/E1BA36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPKKEKGGTTTTGSKIWEPSLIAAQFNQNDWKGSIAFVLGNRIEDEVLIRALTLAVQVPQRRLFSIVSWQDIVQQVNGSSALFGSTSKKAKKPVGGNNAPLYYEVLTAAKAIMDSGEKLTLPLIGKLLKFQLLQIKLKDQQRRESEKKVIEDRFKIEKDKVKAKSPKEKKSPSAKVAKGKGKDQPEANIAVKKTTQLVRRGEEDDTKQYIDDEPDDGAQHYFIVVGFNNPQLLAIMTELGIPISSVIKISSENYEPLQTHLAAVSQQQESFLQPEEIEAEKLKKENGIKELEIFWKYLEPILNNQKPETNLFDVAQLEYTVKADKFPSDWSDSEMLLGLGTDIFENVACLMYDTLDWKRQHQHYLESMRLINVPQVVSEKPIFEVTLIPEPPPPVVAVPGKKKTQAYEEPQIPAPPPATLLPPLPVASVITNEVDMRYYNDLLNPIPEEFISVPLILHCMLEQVVASEEDLVPPSLVEPPPRADGLDYRIAAHIVSILPSLCLTEREKKNLHEIFLSEEENESKPVPTGPLLLNYHDAHAHKKYMLKDLKNFDPVQIEQEMQSKLPLWEFLKFPLPPPWNSTKRLATIHELMHFCTSEVLSWNEVERAFKVFTFESLKLSEVDEDGNLKRSKMMYGTDSEMFNIPWDNPARFAKQIRQQYIMKMNTQEAKQQTDDGAKDRILFLNQNWSTPMPDDALNKEPSDCRQPGSNKKSLDSDNREPTEQERNLKSQLQPETLEQTMNNEIKDEAVTNADLLEKKPKKMTVEAELEDIKKTQQRNLMDWSFTEHFKPKVLLQVLQEANQQYRCIDSYYHTQDNSLLLVFHNPMNLQRLRHEYWKVGLHSNVGFRNYLELVAKSIQDWIIKEEAIYQETKMSDEINKAKYELEIKSSVATKVSSTSKIYSIKKSKSNKGMSKTEISDQEKDKEKEKEKINFILEGSLKAWKEEQDRLAEEERLKEEKKAEKKSKEAVKKKGKEKVEKEDSKIFKKKSFIKEKLKEEQMKIPEVTEEPLQEPEPERVYPFHGYNMGEIPVQISGTNYYLYPSDGGQIEVEKTTFEKGPTFIKVKVKKDKHNFLIHLRDPRKIVEKEEKEGDYLSEDEKEEREREQNFEAEGSNAENKAVSKFGSFSATLENGICLSISYYGSSGSAPEDKDPNLESMLNIPSVHTPTVIPVIVSIPQGKGKGKTKGKEKPKESLKEEEHPKEEEKKEAEEPEPVLQESPRAPIFQNLNVSCPNGLQVTFTGQESPDQCIVDEEPTWDIMVRQTYPQKVKHYEFYKTVMPPLGQEVSRVITSQGTVVKYMLDGSTQILFADGTVSSSPNSGPVSLPTDMPASAHSADLMDTISQQKSETAPSETVITKKGKIQKNQSPMAHKNESHEPPPETVQTITPMDVHLGTWFTTTPQGNRIGTKGSERIADLAPFLFFKATDPVNGTVMTTREDKVIIIEKKDGTRIVDHADGTRITTFYQVYEDPTISSEDQETAEGPQRIARQVKCMRVESSHYATVITNCEDSSCCATFGDGTSIIAKPQGTYQVLPPNTGCLHIDRDCSAIYCHESSSDIYHPFQKREQLRASRYIMKHTSEVICEVMDPEGNTFQVMADGSASTILPENNLEDDLNAKAEGYDSLSSTHLHKNHLQIYGEHVPRFFVIYADGSGVELLRDSDIEEYLSLAYGESTTVVLQEPVQEQPGALSITVLRPFHEVSPWLVKKELDTIVPPNLQSRTWETFPSVQKKTPGPPFGTQIWKGLDIGSKQLVNTPAPILKSPSVLQTRQFIQHEVIKNEVKLKLQISLKDYINHILKKEDELQEMTVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHVTEVAAHLTDLFKQSLANATECPPETFETDFLEKKLRHTETTKRWKEKLAQKRKEIEKTQNYLKEIRSKVISPYFKSELSKLYQSQFNYLDTLSKNLPPLTKKDEDASKEAAQDTSSPPPDSQKNKVSKQESSDILSVSKSENLEDTKEPASQKQTENLTVSIKEPESCMPLKIPTQSLLQDVAGQARKEKVRLPHYLLSSKPKSQPLAKAQDSVGGRVRTSSVASAAINNINSSPFGFHLLPPVVKFGVLEEGHTYATTVKLKNVGVDFCRFRVKQPPPSTGLKVTYTPGPVAAGLQADLKVELFAMAVGEDGTKGLAHISHNIEIMTEHDVLFLPVEATVLTSSNYDKRPKDFPQGKENPMVQRISTISSSALGVFMSRKISPH", "length": 2229, "header": "tr|E1BA36-1|E1BA36_BOVIN Isoform 1 of Sperm associated antigen 17 OS=Bos taurus OX=9913 GN=SPAG17 PE=4 SV=3 CANONICAL=E1BA36-1" }, "isoforms": [ { "isoform_ac": "E1BA36-1", "url": "https://www.uniprot.org/uniprotkb/E1BA36/entry#E1BA36-1", "sequence": { "sequence": "MAPKKEKGGTTTTGSKIWEPSLIAAQFNQNDWKGSIAFVLGNRIEDEVLIRALTLAVQVPQRRLFSIVSWQDIVQQVNGSSALFGSTSKKAKKPVGGNNAPLYYEVLTAAKAIMDSGEKLTLPLIGKLLKFQLLQIKLKDQQRRESEKKVIEDRFKIEKDKVKAKSPKEKKSPSAKVAKGKGKDQPEANIAVKKTTQLVRRGEEDDTKQYIDDEPDDGAQHYFIVVGFNNPQLLAIMTELGIPISSVIKISSENYEPLQTHLAAVSQQQESFLQPEEIEAEKLKKENGIKELEIFWKYLEPILNNQKPETNLFDVAQLEYTVKADKFPSDWSDSEMLLGLGTDIFENVACLMYDTLDWKRQHQHYLESMRLINVPQVVSEKPIFEVTLIPEPPPPVVAVPGKKKTQAYEEPQIPAPPPATLLPPLPVASVITNEVDMRYYNDLLNPIPEEFISVPLILHCMLEQVVASEEDLVPPSLVEPPPRADGLDYRIAAHIVSILPSLCLTEREKKNLHEIFLSEEENESKPVPTGPLLLNYHDAHAHKKYMLKDLKNFDPVQIEQEMQSKLPLWEFLKFPLPPPWNSTKRLATIHELMHFCTSEVLSWNEVERAFKVFTFESLKLSEVDEDGNLKRSKMMYGTDSEMFNIPWDNPARFAKQIRQQYIMKMNTQEAKQQTDDGAKDRILFLNQNWSTPMPDDALNKEPSDCRQPGSNKKSLDSDNREPTEQERNLKSQLQPETLEQTMNNEIKDEAVTNADLLEKKPKKMTVEAELEDIKKTQQRNLMDWSFTEHFKPKVLLQVLQEANQQYRCIDSYYHTQDNSLLLVFHNPMNLQRLRHEYWKVGLHSNVGFRNYLELVAKSIQDWIIKEEAIYQETKMSDEINKAKYELEIKSSVATKVSSTSKIYSIKKSKSNKGMSKTEISDQEKDKEKEKEKINFILEGSLKAWKEEQDRLAEEERLKEEKKAEKKSKEAVKKKGKEKVEKEDSKIFKKKSFIKEKLKEEQMKIPEVTEEPLQEPEPERVYPFHGYNMGEIPVQISGTNYYLYPSDGGQIEVEKTTFEKGPTFIKVKVKKDKHNFLIHLRDPRKIVEKEEKEGDYLSEDEKEEREREQNFEAEGSNAENKAVSKFGSFSATLENGICLSISYYGSSGSAPEDKDPNLESMLNIPSVHTPTVIPVIVSIPQGKGKGKTKGKEKPKESLKEEEHPKEEEKKEAEEPEPVLQESPRAPIFQNLNVSCPNGLQVTFTGQESPDQCIVDEEPTWDIMVRQTYPQKVKHYEFYKTVMPPLGQEVSRVITSQGTVVKYMLDGSTQILFADGTVSSSPNSGPVSLPTDMPASAHSADLMDTISQQKSETAPSETVITKKGKIQKNQSPMAHKNESHEPPPETVQTITPMDVHLGTWFTTTPQGNRIGTKGSERIADLAPFLFFKATDPVNGTVMTTREDKVIIIEKKDGTRIVDHADGTRITTFYQVYEDPTISSEDQETAEGPQRIARQVKCMRVESSHYATVITNCEDSSCCATFGDGTSIIAKPQGTYQVLPPNTGCLHIDRDCSAIYCHESSSDIYHPFQKREQLRASRYIMKHTSEVICEVMDPEGNTFQVMADGSASTILPENNLEDDLNAKAEGYDSLSSTHLHKNHLQIYGEHVPRFFVIYADGSGVELLRDSDIEEYLSLAYGESTTVVLQEPVQEQPGALSITVLRPFHEVSPWLVKKELDTIVPPNLQSRTWETFPSVQKKTPGPPFGTQIWKGLDIGSKQLVNTPAPILKSPSVLQTRQFIQHEVIKNEVKLKLQISLKDYINHILKKEDELQEMTVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHVTEVAAHLTDLFKQSLANATECPPETFETDFLEKKLRHTETTKRWKEKLAQKRKEIEKTQNYLKEIRSKVISPYFKSELSKLYQSQFNYLDTLSKNLPPLTKKDEDASKEAAQDTSSPPPDSQKNKVSKQESSDILSVSKSENLEDTKEPASQKQTENLTVSIKEPESCMPLKIPTQSLLQDVAGQARKEKVRLPHYLLSSKPKSQPLAKAQDSVGGRVRTSSVASAAINNINSSPFGFHLLPPVVKFGVLEEGHTYATTVKLKNVGVDFCRFRVKQPPPSTGLKVTYTPGPVAAGLQADLKVELFAMAVGEDGTKGLAHISHNIEIMTEHDVLFLPVEATVLTSSNYDKRPKDFPQGKENPMVQRISTISSSALGVFMSRKISPH", "length": 2229, "header": "tr|E1BA36-1|E1BA36_BOVIN Isoform 1 of Sperm associated antigen 17 OS=Bos taurus OX=9913 GN=SPAG17 PE=4 SV=3 CANONICAL=E1BA36-1" }, "locus": { "chromosome": "3", "start_pos": 25241698, "end_pos": 25000774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001438.6", "url": "https://www.ensembl.org/id/ENSBTAT00000001438.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001438.6", "url": "https://www.ensembl.org/id/ENSBTAP00000001438.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:535545", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535545", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZU97-1", "protein_name": "Sperm associated antigen 17", "gene_name": "SPAG17", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVDEKLDASKHHVLAAWKANGIMGCIKRGLASREREVIVHLYSAVLCQDLGPPAQERGGAVGEGPEEDMKMIRGLQHLFCEERQRKLGLFSLEKRLQGDIMVFLRVKASLQESWVVEVAKAILDSGEEIPVTLTGKLLKFQLLCIKQKDLQRRASEKAEEQKKEKNGGKEKGKPLGKEKPPSAKATEKERKGKKTETAPPVPDTVKKNTQLKRRGEKEEEYTYIDDEPDDGAHYYFIILGFHNLQLLPVMSELGVYVSSVIRISSENYEPLQTYLEATRFQEESLLSPEDVEAEKIKKNESIKDLETFWKYLEPVLNNGKHGSRLLDVARLHHLVKENAFPSDWSDREILLAFGTELFESIACLMYDCIDWRRQHCNYLESTKFINVPELSESKSTQPPVVTKIPPASQVTSSKKKQQAEEVLTTVIFSQEEEFSFMATSMDMRYYNDLLNQIPEECFSVPIMLNCMLEQVIASEENLTPPSLVVPEERADGIHHKIADHIASVLPSLPLSESEKKNLYDYFSPKYSEETVTPKYPLLFNYHDTLAQRLQLLKIQGNLNPKKIEHEMMDKLPLKELISFTLPSAENDTKRLARVHELMHYCTSELLSWAEVERAFRVFTFESLRLTELSDSGLLESSGSLVGGDSEVSCIPWDNPAKFARQLRQLFLMEMKLTGKSPGGSGHAETNDKDERDGLPDSVLSKELDLSTSDLVSLENYGLEPKLEEIKKTQKRCLTDWNFAEHFHPDVLLQVLHTAAQEYRCIDSYYHTQDKSLLVVLHNPMNQNRLCQETWDVALHSNVGFRNYLELVASSIEDWVKEEEVKYQEEKMAREIKALKQGEGMTEGPSEFSNYAVKKPGLSMNATNSTSRSESIMDTILESQSINEISAFIREGSLKASKEKENQLLEEERLQKEKEAKKENLSGKMKRQEVVTREESEGSNKKTSREKLKDEPAKVPEPEEDPSTPETHSEKIYKFLGYNTGENVIQVSGINHYLFPSDGGQIQVEKIEFVKGLTLVKVKVVKDNHNFFIHITDPKKNLTEIEVHENNQEQKIAPGKIKNQKKAVSKFGSFSATLENGIQLSLSYYGPTGKTADDETDPVLAAILNVPSVHVLTVPPSTTSASGKKDKSVKQKSGKSLPSTKSSNSRISSSPPDNHEKQEGKVEVEEPASQTQVMSAALAFRSLNVSCPNGLVLTFLGESFEDLEGAATTAEATEDEVEKGEVRTDKVREEEVEEGQTKMDEAKEEEAEKDEAKGNEAKEEKAVESEEKEHEVIEGEIKQEDTKREKTKQPALKILVRQSYPQKVKNSRLYASVTSQIKQEVSRVITSQGTVVRYMMDGSTWVLFADGTVSRSPDSGPVLPPPVIPESMQPLSEPEPLPEMDTKRGKGSDKNIVLHPKEEVFEDIIQGIVNPEQPKENQAGTWITTTPLGIQVGTEGGRQMDLEPILLYQATDPADGTIMTVRDDEVIIVEKLDGSRVVDHADGTRITTFYQACEEHLVPQHSKKTGELSETIARKAKCIRVENPKFATVTTNCEDGTCCTIFGDGTSIIAKPQGTYQVLPVKAGSLFIDEDCSAVYTHEVCNSTIEKEGSQAGRYIMKHTSSTICEMMDPEGNLFKVMADGSTSVLVQSTGFDNKENESSTSLLPEVNKSISYDEHVPRFFIIHMDGSGTELLRSKDVEAYLAEACGDPAVAVLQEPVQEYPGAVSITTLFPLSEVSPWVMKKEPECIVPPNLQPRTWNAFSPCEKETTVRTHIWKGLCIGSKEETCLPVPVRKCPKKLQVRQLFQYEPLSDELREKLHLSLKKYIENILRQEDELEEMNLKEPRTEEEKEDAANLLDLVKSFPNWEKSSEDLSAKAHITELYERAVVSQCPLRTEKRVTEKTADQQQSFSTEEQTPVSKWQNKLQEHRKELDEGKETLMAIRNKTIPPYFESELGKAFLSKKFPDVEALSKELPPVPQKESGNLPPETIKNLRRESECLSSMSDSSPSPSLLLQTHSVQREDSSSTADPSLAVESQEAPFQVKVQSLLVNAAGQPRKEKVRLPSSLLGRKPNSIPHKKVEDPVAGRVNISSLATAKQHLSGFHLIPPQMMFGVLKEGCTYAATVVLKNVGINFSRFRVKQPPPYTGLSVMYTPGPVAAGLQVELEIEIFAMPIGGESTNGLEEISHDIEIITETETLLLPVRATVLRSEIFECRPQGYPQGGMAAAVRAVSTSPRPRVRITLPRKLSS", "length": 2228 }, "evidence": [ { "id": "E1BA36", "url": "https://omabrowser.org/oma/group/E1BA36/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZXP4-1", "protein_name": "Sperm associated antigen 17", "gene_name": "Spag17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPKKEKPTGSTSYKIWEPSLIAAHMNQNDWKASIAFVVGNRIEDELPIHALNLAVQLPQRKLFSIVSWKDILQQINEIQALVGATTKKGKKTITGNLPLHYEVLLAAKTIMDNGEKLTLPLVGKLLKFQLLQIKTKDQQRRENEKKMIEERAKSEKDKGKGKSPKEKKAATVKAGKGKSKDQPEATVTVKKTTQLKRRGEDDDTKFYIDIAAENLKRENDIKELEVFWKYLEPILNNEKPETNLLDVARLHYMVKTKHFPSDWSDYEQMLDLGTEIFENVACLMYDSLDWKRQHHHYLQSMQLINVPQVVSDKTMLEAIPIPEPPPSTAPAPGKKKAQYEESHAPPSVAFIITTEVDMRYYNDLLNPIPEEFISVPLILHCMLEQVIATEEDLTPPSLVEPAPRADGLDYRIAAHIVSILPSLCLTEKEKKNLHEIFLTEGESESKTPPKGPLLLNYHDTYAHKKYALKDQKNFDPVQIEEEMQSKLPLWEFLQFPLPPPWNSTKRLATIHELMHFCTNEVLSWNEVERAFKVFTFESLKLSEVDEAGRLKPTEVISETNVENVNIPWDNPARFAKLIRQRYIHRMSIQKAKPVLVETEHKDRTLFVNQNFAKAEQDAQGDENSPNCDHPAANNVMGSTSNSTRPRYSSDRQLTEKETSGSMCPQPESVEQIMDTEIKGGAATKDDSLEKKPKKMVVEADIEDIKKTQQRSLMDWSFTEHFQPKVLLQVLQEAHQQYRCVDSYYHTQDNSLLLVFHNPMNLHHLHCEYWNIALHSNVGFRNYLELVAKSIEEWVIQEEAKYQEAKMAEELNRAKNELDLKATTAKTSASKIGGPKKSKSNKVSSKTELTDQEKDKEKEKEKEKDKIPFILEGSLKAWKEEQERLAEEERLKEEKKAEKKGKEAGRKKGKDKADKEDTKSLKKKSSSKEKPKEEPSKSLEAIEEAVPLPEPEIVYPFRGYNMGDIPIQISGTNYYLYPSDGGQIEVEKIRFERGPTFIKVKVKKDKHSFIIHLKDPKEIVKREKEEEHSEEEEEEEEEEEEEEEEENEQKEGKEENVKQNVEMKRTQIKKEAVSKFGSFSATLENGICLSISYYGSNGMAPEVMDSDLEAMMNIPSAMTATVVPSIVTVPQGKGKTKPKGKEKHKDSFKEEELPKEEEKKNHSQEEVEPEIVIQETPYVPTFQNLNVSCPNGLLLTFIGQESTDEESTWNLMIRQSYPQRLKHYEFYKAVMPPTEQEASRVVTSQGTVIKYMLDGSTQILFADGAVSSSPDSGPVHASPETSASPHNGDVADNTSQHKSETAPSEIITKKGKGHKNQTSTASKSEAHDTLPEVVPTPMESHTGTWFTTTPDGRRIGTKGLEKITNLKPFLFFQATDPINGTVMTTREDKVIIVEKKDGTRIVDHADGTRITTFYQVYEDHITPPNDEETTEDPRTVTRQVKCMRIESSHYATIITNCEDSSCCATFGDGTSIIAKPQGSYQVLPSNTGCLYIDKDCSATYCHELSSNMYHPFQKREELRASRYIMKHTSEVICEVQDPEGNIFKVMADGSVSTALPKKKLEDKLNVQTEGYESLSSLHLEKNRMQIYGEHVPRFFVVYTDGSGVELLRDSDIEEYLSLAYGESTTVVLQEPVQEHPGALSITVLRPFHEASQWIMKKELDSIVPPNLQSRSWETFPSVEKKTPGPPFGTQIWKGLCIGAKQLTNIPAPILEGPKVLQMRQFIQHEVIKNEVKLKLQISLKDYINHILKKEDEQQEMTVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHVTEVAAHLTDLFKQSMASAPKCSPENFTKDFFEKKWREAPQGKSWKEKLEQQRNNIKKTQNYLMQIRTKEVTPYFKSELSPLIKSQYDYLEKLSKNLPPFTKKNEAETKTADPDLHSDSTLTVDAKKEVSDAHPLPNQEVAENSQESTGQKETEYVTKYLQTSSPPNQYEHLTKSPKESYSQSQSEIETNATKEPAGQNHTEKFKISTKKSASQNQIENLIKSTKEPAGQSQMENISRPPTEEPENFMPIKIPTQSLLQDVTGKARKEKVRLPHYMMSCKPKCQPHTKVEDSVGGKVNTSSIACAAIYNPDVSPFGFHLLPPSIQFGVLKEGHTYATIVKLKNVGVDFCRFRVKQPPPSTGLKVTYKPGPVAAGLQAELKVELFAMAVGEDGAKDSAHISHTIEILTEHDVLFLPVEATVLTSSNYDNRPKDLPQGRENPMVYRTSTISSSALGVVMSQKATRH", "length": 2254 }, "evidence": [ { "id": "E1BA36", "url": "https://omabrowser.org/oma/group/E1BA36/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5S003-1", "protein_name": "Sperm-associated antigen 17", "gene_name": "Spag17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKKEKPTGSANYKIWEPSLIAAHLNQNDWKASIAFVVGNRVEDDLLIHALDLAVRLPQRKLFSIVSWEDILQQMDEIQSLAESASAKKGKKPTSVNLPLHYEVFLAAKIIMESGEKLTLPLIGKLLKCQLLHIKSKDQQRRENEKKMVEERTKSEKDKGKGKSPKEKKVASAKPGKGKSKDQPEATVTVRKTTQLKRRGEDDEAKSYIDDEPDDGAQYYIIVVGFNNPQLLAIMTELGIPITSVIKISSENYEPLQTHLAAVRQQQEAVLQPEDIEAEKLKRKNSIKELEVFWKYLEPILNNEKLEIHLFDVARLQYMVKATYFPSDWSDNEQMLALGTEIFENIACLMYDSLDWKRQHHHYLQSMQLINVPQVVSEKTVLEAITIPEPPPSTAPAPTGKKKAQYEESHAPPTVAFIITTEVDMRYYNDLLNPIPEEFISVSLILHCMVEQVVATEEDLIPPSLVEPAPRADGLDYRIAAHIVSILPSLCLSEKEKKNLREIFLTEGESESKALPKGPLLLNYHDAHAHKKYALKDQKNFDPVQVEQEMQSKLPLWEFLQFPLPPPWNSTKRLATIHELMHFCTNEVLSWNEVERAFKVFTFESLKLSEVDEEGRLKPTETTSDTDVENFNIPWDNPARFAKLIRQRYIHRMSMQKAPPVVVEIENTERTLFVNKNFAKAEQDAQGDENSPNSDEPDAISVTGSTSNSTKPWNSSNRQFSEKETSGSMWPQPESMDQTMDTEIKDDAATKDDSPEKKPKKMVVEADIEDIKKTQQRSLMDWSFTEYFQPKVLLQVLQEAHQQYRCVDSYYHTQDNSLLLVFHNPMNLQRLQCEHWNIALHSNVGFRNYLELVAKSIEDWVTQEEAKYQEAKMAEELNRIRIELELKATVKTSASKIPGPKRSKTNKVSSKTELSDQEKDKEKEKDKIPFVLEGSLKAWKEEQERLAEEERLKEEKKAEKKGKDTGKKKGKDKADKDDAKALKKKSSSKEKPKEEPAKTLEVIEETAPLPVPEVVYPFRGYNMGDIPIQISGTNYYLYPSDGGQIEVEKTRFERGSTFIKVKVKKDKHNFIIHLKDPKEIVKKEKEEKNSEEEEEEEEEKEEVEEKKPKEGEEEKVKQKVEMKRAQIEKEAVSKFGSFSATLENGICLSISYYGSNGMAPEVINSELEAMMNIPSAMTATVVPAVVTVPQGKGKAKPKGKEKHKDSIKEEELPKEEEKKNHIQEEVEPEIVIQESPPYVPTFQNLNVSCPSGLLLTFIGQESTDYSIVDEEPTRNLMIRQSYPQRLKHYEFYKAVMPPLEQEASRVVTSQGTVIKYMLDGSTQILFADGAVSSSPDSGPVYTSPELPTSPHNGDLVDSASQPKSETGPEIIITKKGKGHKNQTVANKSETHDIIPEVPPPTPVESHIGTWFTTTPDGRRIGTKGLEKIEDLKPYLFFQATDPINGTVMTTREDKVIIVEKKDGTRVVDHADGTRITTFYQVYEDHITPSNDEETTEGPRTVTRQVKCMRIESSHYATIITNCEDSSCCATFGDGTSIIAKPQGSYQVLPPNTGCLYIDKDCSATYCHESSNNLYHPFQKREQLRASRYIMKHTSEVICEVQDPEGNTFQVMADGSVSTTLPKKKLEDDFNVQMEGYESLSSLHLEKNHMQIYGEHVPRFFVVYTDGSGVELLRDSDIEEYLSLAYGESTTVVLQEPVQEYPGALSITVLRPFHEASQWIMKKELDTIVPPNLQSRSWERFPSVEKKTPGPPFGTQIWKGLSIGSKQLTNIPAPILEGPKVLQMRQFIQHEVIKNEVKLKLQISLKDYINHILKKEDELQEMTVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHMTKVAAHLTVLFKQSMASAPKCSPDSYSKEFLEKKWRSLSQGTSWKEKLEQQRNNIKKTQSYLMQIKTKEVTPYFKSELSSLFKSKYDYLEKFSKSLPPFVKKNEAKLMTAVPDLYSDSTLTVDTEKEASNTHPLLNQEVAENIQESPREKETEYVNKSLQTSSSQNQYENVTISPKESVYQSQTEIETKDTKESAIQNFTEKFKKYTKKSASQNEIEDLIKSTKESVSQRQTENVTRPPTEEPDIYMPIKIPTQSLLQDVTGQARKEKVRLPYYMMSSKPKSQPYAKVEDPVGGRVNTSSIASAAMYNPNASPFGFHLLPPSVKFGVLKEGHTYATIVKLKNVGVDFCRFRVKQPPPSTGLKVTYKPGPVAAGLQAELKVELFAMAVGEDGAKGSAHISHNIEIMTEHDVLFLPVEATVLTSSNYDNRPKNLPQGKENPMVFRTSTISSSSLGVVMSQKATHH", "length": 2320 }, "evidence": [ { "id": "E1BA36", "url": "https://omabrowser.org/oma/group/E1BA36/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6Q759-1", "protein_name": "Sperm-associated antigen 17", "gene_name": "SPAG17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPKKEKGGTVNTSSKIWEPSLIAAQFNQNDWQASIAFVVGNQIEDDLLIQALTVAVQVPQRKLFSMVSWQDILQQINEINTLVGSASSKKAKKPVGGNAPLYYEVLTAAKAIMDSGEKLTLPLIGKLLKFQLLQIKFKDQQRRENEKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKGKGKDQPEANAPVKKTTQLKRRGEDDHTNRYIDDEPDDGAQHYIIVVGFNNPQLLAIMAELGIPITSVIKISSENYEPLQTHLAAVNQQQEVLLQSEDLEAEKLKKENAIKELKTFWKYLEPVLNNEKPETNLFDVARLEYMVKAADFPSDWSDGEMMLKLGTDIFENIACLMYDILDWKRQHQHYLESMQLINVPQVVNEKPVLEAMPTSEAPQPAVPAPGKKKAQYEEPQAPPPVTSVITTEVDMRYYNYLLNPIREEFISVPLILHCMLEQVVATEEDLVPPSLREPSPRADGLDHRIAAHIVSLLPSLCLSEREKKNLHDIFLSEEENESKAVPKGPLLLNYHDAHAHKKYALQDQKNFDPVQIEQEMQSKLPLWEFLQFPLPPPWNNTKRLATIHELMHFCTSDVLSWNEVERAFKVFTFESLKLSEVDEKGKLKPSGMMCGSDSEMFNIPWDNPARFAKQIRQQYVMKMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMKHSDLNNLKLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMAPEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKKEEEVEPEPVLQETLDVPTFQSLNVSCPSGLLLTFIGQESTGQYVIDEEPTWDIMVRQSYPQRVKHYEFYKTVMPPAEQEASRVITSQGTVVKYMLDGSTQILFADGAVSRSPNSGLICPPSEMPATPHSGDLMDSISQQKSETIPSEITNTKKGKSHKSQSSMAHKGEIHDPPPEAVQTVTPVEVHIGTWFTTTPEGNRIGTKGLERIADLTPLLSFQATDPVNGTVMTTREDKVVIVERKDGTRIVDHADGTRITTFYQVYEDQIILPDDQETTEGPRTVTRQVKCMRVESSRYATVIANCEDSSCCATFGDGTTIIAKPQGTYQVLPPNTGSLYIDKDCSAVYCHESSSNIYYPFQKREQLRAGRYIMRHTSEVICEVLDPEGNTFQVMADGSISTILPEKKLEDDLNEKTEGYDSLSSMHLEKNHQQIYGEHVPRFFVMYADGSGMELLRDSDIEEYLSLAYKESNTVVLQEPVQEQPGTLTITVLRPFHEASPWQVKKEDTIVPPNLRSRSWETFPSVEKKTPGPPFGTQIWKGLCIESKQLVSAPGAILKSPSVLQMRQFIQHEVIKNEVKLRLQVSLKDYINYILKKEDELQEMMVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHVTEVAAHLTDLFKQSLATPPKCPPDTFGKDFFEKTWRHTASSKRWKEKIDKTRKEIETTQNYLMDIKNRIIPPFFKSELNQLYQSQYNHLDSLSKKLPSFTKKNEDANETAVQDTSDLNLDFKPHKVSEQKSSSVPSLPKPEISADKKDFTAQNQTENLTKSPEEAESYEPVKIPTQSLLQDVAGQTRKEKVKLPHYLLSSKPKSQPLAKVQDSVGGKVNTSSVASAAINNAKSSLFGFHLLPSSVKFGVLKEGHTYATVVKLKNVGVDFCRFKVKQPPPSTGLKVTYKPGPVAAGMQTELNIELFATAVGEDGAKGSAHISHNIEIMTEHEVLFLPVEATVLTSSNYDKRPKDFPQGKENPMVQRTSTIYSSTLGVFMSRKVSPH", "length": 2223 }, "evidence": [ { "id": "E1BA36", "url": "https://omabrowser.org/oma/group/E1BA36/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "axonemal central apparatus assembly", "id": "GO:1904158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904158", "evidence": [ { "database": "UniProtKB", "id": "E1BA36", "url": "https://www.uniprot.org/uniprotkb/E1BA36" } ], "pmid": "" }, { "name": "epithelial cilium movement involved in extracellular fluid movement", "id": "GO:0003351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003351", "evidence": [ { "database": "UniProtKB", "id": "E1BA36", "url": "https://www.uniprot.org/uniprotkb/E1BA36" } ], "pmid": "" }, { "name": "motile cilium assembly", "id": "GO:0044458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044458", "evidence": [ { "database": "UniProtKB", "id": "E1BA36", "url": "https://www.uniprot.org/uniprotkb/E1BA36" } ], "pmid": "" }, { "name": "manchette assembly", "id": "GO:1905198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905198", "evidence": [ { "database": "UniProtKB", "id": "E1BA36", "url": "https://www.uniprot.org/uniprotkb/E1BA36" } ], "pmid": "" }, { "name": "intramanchette transport", "id": "GO:1990953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990953", "evidence": [ { "database": "UniProtKB", "id": "E1BA36", "url": "https://www.uniprot.org/uniprotkb/E1BA36" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "axonemal central apparatus", "id": "GO:1990716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990716", "evidence": [ { "database": "UniProtKB", "id": "E1BA36", "url": "https://www.uniprot.org/uniprotkb/E1BA36" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BA36", "url": "https://www.uniprot.org/uniprotkb/E1BA36" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BA36", "url": "https://www.uniprot.org/uniprotkb/E1BA36" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "E1BA36", "url": "https://www.uniprot.org/uniprotkb/E1BA36" } ], "pmid": "" }, { "name": "manchette", "id": "GO:0002177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002177", "evidence": [ { "database": "UniProtKB", "id": "E1BA36", "url": "https://www.uniprot.org/uniprotkb/E1BA36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1231, "end_pos": 1233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1367, "end_pos": 1369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1375, "end_pos": 1377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1432, "end_pos": 1434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1861, "end_pos": 1863, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2001, "end_pos": 2003, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2076, "end_pos": 2078, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1231, "end_pos": 1233 }, { "start_pos": 1367, "end_pos": 1369 }, { "start_pos": 1375, "end_pos": 1377 }, { "start_pos": 1432, "end_pos": 1434 }, { "start_pos": 1861, "end_pos": 1863 }, { "start_pos": 2001, "end_pos": 2003 }, { "start_pos": 2076, "end_pos": 2078 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 581, "end_pos": 583 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BA55-1", "uniprot_ac": "E1BA55", "uniprot_id": "E1BA55_BOVIN", "mass": { "chemical_mass": 35020.0, "monoisotopic_mass": 35020.0 }, "refseq": { "ac": "NP_001377328", "name": "olfactory receptor family 2 subfamily P member 2", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377328" }, "gene_names": [ { "name": "OR2P2", "type": "recommended", "evidence": [ { "id": "E1BA55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA55" } ] }, { "name": "OR2P2", "type": "synonym", "evidence": [ { "id": "NP_001377328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377328" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BA55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA55/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2B11", "type": "synonym", "evidence": [ { "id": "NP_001377328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377328" } ] }, { "name": "olfactory receptor family 2 subfamily P member 2", "type": "synonym", "evidence": [ { "id": "NP_001377328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377328" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377328" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BA55", "url": "https://www.uniprot.org/uniprotkb/E1BA55#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BA55", "url": "https://www.uniprot.org/uniprotkb/E1BA55" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2P2", "url": "https://www.uniprot.org/uniprotkb/E1BA55", "locus": { "chromosome": "23", "start_pos": 29662604, "end_pos": 29661663, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040582", "url": "https://www.ensembl.org/id/ENSBTAG00000040582" } ] } } ], "crossref": [ { "id": "E1BA55", "url": "https://alphafold.ebi.ac.uk/entry/E1BA55", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "784681", "url": "https://www.ncbi.nlm.nih.gov/gene/784681", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"MNAGNASTPKFFILLGFSDHPWLEMPLFTVVLAAYICTLVGNISIIVVSRVDPQLDSPMYFFLSNLSFLDVCFTTTTTPQLLLNLWGPDKSITYGGCVTQFYVFHFLGATECILLAMMSLDRYVAICKPLRYPVIMQQQLCIFLVVMAWLSGLANSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCADTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHVIVVSLFYGPVISMYVQPSTNSQDKNKLMSLSYSLVTPMLNPFIYTLRNKDMKRAMTSLLVLLYHQRRE", "length": 313, "header": "tr|E1BA55-1|E1BA55_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2P2 PE=3 SV=4 CANONICAL=E1BA55-1" }, "isoforms": [ { "isoform_ac": "E1BA55-1", "url": "https://www.uniprot.org/uniprotkb/E1BA55/entry#E1BA55-1", "sequence": { "sequence": "MNAGNASTPKFFILLGFSDHPWLEMPLFTVVLAAYICTLVGNISIIVVSRVDPQLDSPMYFFLSNLSFLDVCFTTTTTPQLLLNLWGPDKSITYGGCVTQFYVFHFLGATECILLAMMSLDRYVAICKPLRYPVIMQQQLCIFLVVMAWLSGLANSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCADTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHVIVVSLFYGPVISMYVQPSTNSQDKNKLMSLSYSLVTPMLNPFIYTLRNKDMKRAMTSLLVLLYHQRRE", "length": 313, "header": "tr|E1BA55-1|E1BA55_BOVIN Isoform 1 of Olfactory receptor 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"id": "Q58DS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DS5" } ] } ] }, { "uniprot_ac": "Q58DS9", "gene_name": "RAB5C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q58DS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DS9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q58DS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DS9" } ] } ] }, { "uniprot_ac": "Q58DW6", "gene_name": "RAB25", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q58DW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DW6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q58DW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DW6" } ] } ] }, { "uniprot_ac": "Q5E9J3", "gene_name": "RASL11B", "activity": [ { 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"binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 335, "end_pos": 337 }, { "start_pos": 377, "end_pos": 379 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BA63-1", "uniprot_ac": "E1BA63", "uniprot_id": "E1BA63_BOVIN", "mass": { "chemical_mass": 28534.0, "monoisotopic_mass": 28534.0 }, "refseq": { "ac": "XP_002698770", "name": "homeobox protein Nkx-6.3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698770" }, "gene_names": [ { "name": "NKX6-3", "type": "recommended", "evidence": [ { "id": "E1BA63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA63" } ] }, { "name": "NKX6-3", "type": "synonym", "evidence": [ { "id": "XP_002698770", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698770" } ] } ], "protein_names": [ { "name": "NK6 homeobox 3", "type": "synonym", "evidence": [ { "id": "E1BA63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA63/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein Nkx-6.3", "type": "synonym", "evidence": [ { "id": "XP_002698770", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698770" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BA63", "url": "https://www.uniprot.org/uniprotkb/E1BA63" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NKX6-3", "url": "https://www.uniprot.org/uniprotkb/E1BA63", "locus": { "chromosome": "27", "start_pos": 36555810, "end_pos": 36561553, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018495", "url": "https://www.ensembl.org/id/ENSBTAG00000018495" } ] } } ], "crossref": [ { "id": "E1BA63", "url": "https://alphafold.ebi.ac.uk/entry/E1BA63", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018495", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018495", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "784372", "url": "https://www.ncbi.nlm.nih.gov/gene/784372", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:784372", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784372", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EMKAPMC", "url": "https://omabrowser.org/oma/group/EMKAPMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BA63", "url": "https://www.orthodb.org/?gene=E1BA63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24340:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24340:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002698770", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698770", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BA63", "url": "https://www.uniprot.org/uniprotkb/E1BA63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BA63-1", "url": "https://www.uniprot.org/uniprotkb/E1BA63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESNLQGPFLLNNTPLAQFSEMKAPVCQYSMQNSFYKLSPPGLGPQLPAGTPHGITDILSRPVAAPNSSILPGYPHVAGFGGLGSQGVYYGPQVGSFSKAGSEYPTRTRNCWADAGQDWRGGRQCGSTPDALGNSIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSALEPSSSTPRAPGSAGAGGERAASETEDDEYNKPLDPDSDDEKIRLLLRKHRAAFSVLGLGAHGV", "length": 263, "header": "tr|E1BA63-1|E1BA63_BOVIN Isoform 1 of NK6 homeobox 3 OS=Bos taurus OX=9913 GN=NKX6-3 PE=4 SV=2 CANONICAL=E1BA63-1" }, "isoforms": [ { "isoform_ac": "E1BA63-1", "url": "https://www.uniprot.org/uniprotkb/E1BA63/entry#E1BA63-1", "sequence": { "sequence": "MESNLQGPFLLNNTPLAQFSEMKAPVCQYSMQNSFYKLSPPGLGPQLPAGTPHGITDILSRPVAAPNSSILPGYPHVAGFGGLGSQGVYYGPQVGSFSKAGSEYPTRTRNCWADAGQDWRGGRQCGSTPDALGNSIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSALEPSSSTPRAPGSAGAGGERAASETEDDEYNKPLDPDSDDEKIRLLLRKHRAAFSVLGLGAHGV", "length": 263, "header": "tr|E1BA63-1|E1BA63_BOVIN Isoform 1 of NK6 homeobox 3 OS=Bos taurus OX=9913 GN=NKX6-3 PE=4 SV=2 CANONICAL=E1BA63-1" }, "locus": { "chromosome": "27", "start_pos": 36561354, "end_pos": 36556814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047361.4", "url": "https://www.ensembl.org/id/ENSBTAT00000047361.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044573.2", "url": "https://www.ensembl.org/id/ENSBTAP00000044573.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:784372", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784372", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ARG6-1", "protein_name": "NK6 homeobox 3", "gene_name": "NKX6-3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESNLQGPFLLNNAPLAQFSEMKAPVCQYSVQNSFYKLSPPGLGPQLPAGTPHGITDILSRPVATPNSSLLSGYPHVAGFGGLGSQGVYYSPQVGNFSKAATEYPTRTRNCWADAGPDWRGGRQCGNAPDPLSDSIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSALEPSSSTPRAPGGAGGDRPASENEDDEYNKPLDPDSDDEKIRLLLRKHRAAFSVLSLGAHGV", "length": 261 }, "evidence": [ { "id": "E1BA63", "url": "https://omabrowser.org/oma/group/E1BA63/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6NJ46-1", "protein_name": "Homeobox protein Nkx-6.3", "gene_name": "NKX6-3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESNLQGTFLLNNTPLAQFPEMKAPVCQYSVQNSFYKLSPPGLGPQLAAGTPHGITDILSRPVAAPNNSLLSGYPHVAGFGGLSSQGVYYSPQVGNFSKAGNEYPTRTRNCWADTGQDWRGGRQCSNTPDPLSDSIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSALEPSSSTPRAPGGAGAGAGGDRAPSENEDDEYNKPLDPDSDDEKIRLLLRKHRAAFSVLSLGAHSV", "length": 265 }, "evidence": [ { "id": "E1BA63", "url": "https://omabrowser.org/oma/group/E1BA63/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZCL0-1", "protein_name": "NK6 homeobox 3", "gene_name": "Nkx6-3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESNLQGTFLLNNTQLAQFSEMKAPMCQYSVQNSFYKLSPPGLGPQLAAGTPHGITDILSRPVATPNSSLLSGYPHVAGFGGLSSQGVYYGPQVGSFSKTGNEYPTRTRNCWADTGQDWRGSTRPCSNTPDPLSDTIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSALEPSSSTPRAPGGASGDRAASENEDDEYNKPLDPDSDDEKIRLLLRKHRAAFSVLSLGAHSV", "length": 262 }, "evidence": [ { "id": "E1BA63", "url": "https://omabrowser.org/oma/group/E1BA63/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C0H3-1", "protein_name": "NK6 homeobox 3", "gene_name": "NKX6-3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDANLPGTFLLSGPSLAPFPEAKAPVCQYSVQSSFYKLGPPGLGAQLAAGTPHGISDILGRPTATPNSSLLPSYPHTGGFNGLSSPGVYYGPQVGALPKASSDYVPRGRSCWAEAPDWQGSRQCGGPPAHLTDSLHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSALEPSSSSQRVGGSSGERAASETEDDEYNKPLDPDSDDEKIRLLLRKHRAAFSVLGLGTHSG", "length": 259 }, "evidence": [ { "id": "E1BA63", "url": "https://omabrowser.org/oma/group/E1BA63/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RAI4-1", "protein_name": "Homeobox protein Nkx-6.3", "gene_name": "nkx6.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESNISGSFLFNNSLNQFPSDIKAPVCQYSIPNSFYKLGPANINSQLQAGTPHGISDILSRSMVSGPGTPALLSGYPSMGGFGTTVPSPGVYYNRDYTPSGLSTFPKPVVECAGMKGKSSSCWVDGGYEWRGARQQCGNNMGHNPENVGKKKHTRPTFSGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSATEPSSTQTSRGESAGDGSENEVEDEEYNKPLDPDTDDEKIRQLLRKHRRAFSVLRLGPHHI", "length": 272 }, "evidence": [ { "id": "E1BA63", "url": "https://omabrowser.org/oma/group/E1BA63/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HHI2-1", "protein_name": "Homeobox protein Nkx-6.3", "gene_name": "Nkx6-3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESNLQGTFLLNNTQLAQFSEMKAPMCQYSVQNSFYKLNPPGLGPQLAAGTPHGITDILSRPVATPNSSLLSGYPHVAGFGGLGSQGVYYGPQVGSFSKAGNEYPTRTRNCWADTGQDWRGGARPCSNTPDPLSDTIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSALEPSSSTPRAQGGAGGDRAASENEDDEYNKPLDPDSDDEKIRLLLRKHRAAFSVLSLGAHSV", "length": 262 }, "evidence": [ { "id": "E1BA63", "url": "https://omabrowser.org/oma/group/E1BA63/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3UHX8-1", "protein_name": "Homeobox protein Nkx-6.3", "gene_name": "Nkx6-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESNLQGTFLLNNTQLAQFSEMKAPMCQYSVQNSFYKLSPPGLGPQLAAGTPHGITDILSRPVATPNSSLLSGYPHVAGFGGLSSQGVYYGPQVGSFSKAGNEYPTRTRNCWADTGQDWRGSARPCSNTPDPLSDTIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSALEPSSSTPRAPGGASGDRAASENEDDEYNKPLDPDSDDEKIRLLLRKHRAAFSVLSLGAHSV", "length": 262 }, "evidence": [ { "id": "E1BA63", "url": "https://omabrowser.org/oma/group/E1BA63/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BA63", "url": "https://www.uniprot.org/uniprotkb/E1BA63" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BA63", "url": "https://www.uniprot.org/uniprotkb/E1BA63" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BA63", "url": "https://www.uniprot.org/uniprotkb/E1BA63" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, 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"https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BA63", "url": "https://www.uniprot.org/uniprotkb/E1BA63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BA63-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 263, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BA63-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BA63" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BA63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA63" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 137, "end_pos": 197, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BA69-1", "uniprot_ac": "E1BA69", "uniprot_id": "E1BA69_BOVIN", "mass": { "chemical_mass": 51019.0, "monoisotopic_mass": 51019.0 }, "refseq": { "ac": "NP_001179191", "name": "zinc finger protein 296", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179191" }, "gene_names": [ { "name": "ZNF296", "type": "recommended", "evidence": [ { "id": "E1BA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA69" } ] }, { "name": "ZNF296", "type": "synonym", "evidence": [ { "id": "NP_001179191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179191" } ] }, { "name": "ZNF342", "type": "synonym", "evidence": [ { "id": "NP_001179191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179191" } ] } ], "protein_names": [ { "name": "Zinc finger protein 296", "type": "synonym", "evidence": [ { "id": "E1BA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA69/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 296", "type": "synonym", "evidence": [ { "id": "NP_001179191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179191" } ] }, { "name": "zinc finger protein 342", "type": "synonym", "evidence": [ { "id": "NP_001179191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179191" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BA69", "url": "https://www.uniprot.org/uniprotkb/E1BA69" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF296", "url": "https://www.uniprot.org/uniprotkb/E1BA69", "locus": { "chromosome": "18", "start_pos": 52749714, "end_pos": 52753732, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013702", "url": "https://www.ensembl.org/id/ENSBTAG00000013702" } ] } } ], "crossref": [ { "id": "E1BA69", "url": "https://alphafold.ebi.ac.uk/entry/E1BA69", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013702", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013702", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539503", "url": "https://www.ncbi.nlm.nih.gov/gene/539503", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539503", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539503", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RNQWALW", "url": "https://omabrowser.org/oma/group/RNQWALW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BA69", "url": "https://www.orthodb.org/?gene=E1BA69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45993", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45993", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45993:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45993:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25491", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25491", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179191", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BA69", "url": "https://www.uniprot.org/uniprotkb/E1BA69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BA69-1", "url": "https://www.uniprot.org/uniprotkb/E1BA69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRKAGCMPRRIEPPPAASSDDEMEMRDLVIDVKPEPDPRPLQAPGLGPFTPKEVPAPERFESEPRHCAGPVSTGGLIHALGLRNQWTPLSLSPHDRQPWTDKHPDLLTCGRCMQTFPLEAITAFVDHKKLGCQLFRGPSPCQGSEHEDLKALNCLRCGRQFTGAWKLLRHAQWDHGLSIYQTEPESPEAPLLGLAEVAVAVSAVSSVVGPEAEVKGSRVGPTRRSPTCPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPYACAQSSKLNRHKKTHRQLQPQSPCLADTGQEQASTAPPEPAAHAAAPASVLPCRGGEGAGAAATAGVQEPGAPGGGAQVGPGGDSWGADTKERRTDQEKNQKMSPKKTLKPAGKNRGPGPGGSCEFCGKHFTNSSNLTVHRRSHTGERPYACELCSYACAQSSKLNRHRRMHGLGPGGPRFACPHCCVPFGLRATLDKHLRQKHPEMAGEA", "length": 474, "header": "tr|E1BA69-1|E1BA69_BOVIN Isoform 1 of Zinc finger protein 296 OS=Bos taurus OX=9913 GN=ZNF296 PE=4 SV=3 CANONICAL=E1BA69-1" }, "isoforms": [ { "isoform_ac": "E1BA69-1", "url": "https://www.uniprot.org/uniprotkb/E1BA69/entry#E1BA69-1", "sequence": { "sequence": "MSRRKAGCMPRRIEPPPAASSDDEMEMRDLVIDVKPEPDPRPLQAPGLGPFTPKEVPAPERFESEPRHCAGPVSTGGLIHALGLRNQWTPLSLSPHDRQPWTDKHPDLLTCGRCMQTFPLEAITAFVDHKKLGCQLFRGPSPCQGSEHEDLKALNCLRCGRQFTGAWKLLRHAQWDHGLSIYQTEPESPEAPLLGLAEVAVAVSAVSSVVGPEAEVKGSRVGPTRRSPTCPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPYACAQSSKLNRHKKTHRQLQPQSPCLADTGQEQASTAPPEPAAHAAAPASVLPCRGGEGAGAAATAGVQEPGAPGGGAQVGPGGDSWGADTKERRTDQEKNQKMSPKKTLKPAGKNRGPGPGGSCEFCGKHFTNSSNLTVHRRSHTGERPYACELCSYACAQSSKLNRHRRMHGLGPGGPRFACPHCCVPFGLRATLDKHLRQKHPEMAGEA", "length": 474, "header": "tr|E1BA69-1|E1BA69_BOVIN Isoform 1 of Zinc finger protein 296 OS=Bos taurus OX=9913 GN=ZNF296 PE=4 SV=3 CANONICAL=E1BA69-1" }, "locus": { "chromosome": "18", "start_pos": 52753533, "end_pos": 52749820, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018207.5", "url": "https://www.ensembl.org/id/ENSBTAT00000018207.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018207.4", "url": "https://www.ensembl.org/id/ENSBTAP00000018207.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539503", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539503", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A2P2-1", "protein_name": "Zinc finger protein 296", "gene_name": "ZNF296", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRRKAGCTPRRIDPAPAANPDDETEMPDLVICVKPEPDARPLQAPGLGPFNPKEVPAPGLSEGESRHPHGPVPAAGLIHALGLRSQCAAWTPLTPNPQDRQPWTDKHPDLLTCGRCTQTFPLEAITAFMDHKKLGCQLFRGPSPSQGSERDDLKALSCLRCGRQFTGAWKLLRHVQWDHGLSIYQTEPELPEAPLLGLAEVAAAVSAVAGPEAEAKGPRVGHPRRSPTCPMCAKTLSSFSNLKVHMRSHTGERPYACDQCPYACAQSSKLNRHKKTHRQLQPQSPCSAGSSQELASAAPPEPAAHAAAPASALPCSGGEGAGAAATAGVQEPGAPGSGAQAGPGGDGWAVATKEQRTDPTKTQKTSPKKAPKAVGKSRGPGPGGSCEFCGKHFTNSSNLTVHRRSHTGERPYACELCSYACAQSSKLNRHRRMHGLGPGGPRFECPHCCVPFGLRATLDKHLRQKHPEVGGDA", "length": 474 }, "evidence": [ { "id": "E1BA69", "url": "https://omabrowser.org/oma/group/E1BA69/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E9Q6W4-1", "protein_name": "Zinc finger protein 296", "gene_name": "Znf296", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRRKAGRVPRRVDPDTDTDIEMPDLVMDVKPDLDLRSLAQGPWIARDMPISDVKRQLQTASRPLGAPSTCAPRMPLSSKSSDRQPWTDKHPDLLTCGRCGKIFPLGAIIAFMDHKKQGCQLLQVSDPISESKELKALSCLQCGRQYTSPWKLLCHAQWDHGLCIYQTQHLDTPEAPLLGLAEVAAAMSAVAVVAPVESKPPPVSSAARRSPTCDVCKKTLSSFSNLKVHMRSHTGERPYSCDQCSYACAQSSKLNRHKKTHRQLAPGSPSTSASSRGVSPAAPPEPAAYAAAPASTLPSQTVEKAGAAATAGVQEPGAPGSGAQGGPGFVGWGAPAKVERTDPVKIEKTAPRKSHGPGGKCEFCGKSFTNSSNLTVHRRSHTGERPYTCDQCPYACAQSSKLNRHRRTHGLGTGKTVKCPHCLVPFGLQATLDKHLRQKHPEMA", "length": 445 }, "evidence": [ { "id": "E1BA69", "url": "https://omabrowser.org/oma/group/E1BA69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3W4-1", "protein_name": "Zinc finger protein 296", "gene_name": "Zfp296", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTTSRLGDEGLHPEPQAGRVPRRVDPEPNDDMEMPDLIIDVKPDRDLGSLAQGPWSARDVPMPGLFDVERRLQTASRPLGAPSTCAPWMPLSSMSSDRQPWTDKHPDLLTCGRCGKIFPLGSITAFMDHKKQGCQLRQISDPISESKELKALSCLQCGRQYTSAWKLLCHAQWDHGLCIYQTQQLETPEAPLLGLAEVAAAMSAVAVVGPVEDKPPSVSSAARRSPTCFVCKKTLSSFSNLKVHMRSHTGERPYSCDQCSYSCAQSSKLNRHKKTHRQPTPGSPSTSASSREVSPAAPPEPAAYAAAPASTPPCQNVEKAGAAATAGIQEPGAPGSGAQESPGFGGCGATAKVERTDSVKMEKTTPRKSHRAGGKCEFCGKSFTNSSNLTVHRRSHTGERPYTCDQCSYACAQSSKLNRHRRTHGLGTGKTVYKCPHCLVPFVLQATLDKHLRQKHPEMA", "length": 461 }, "evidence": [ { "id": "E1BA69", "url": "https://omabrowser.org/oma/group/E1BA69/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WUU4-1", "protein_name": "Zinc finger protein 296", "gene_name": "ZNF296", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRRKAGSAPRRVEPAPAANPDDEMEMQDLVIELKPEPDAQPQQAPRLGPFSPKEVSSAGRFGGEPHHSPGPMPAGAALLALGPRNPWTLWTPLTPNYPDRQPWTDKHPDLLTCGRCLQTFPLEAITAFMDHKKLGCQLFRGPSRGQGSEREELKALSCLRCGKQFTVAWKLLRHAQWDHGLSIYQTESEAPEAPLLGLAEVAAAVSAVVGPAAEAKSPRASGSGLTRRSPTCPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPYACAQSSKLNRHKKTHRQVPPQSPLMADTSQEQASAAPPEPAVHAAAPTSTLPCSGGEGAGAAATAGVQEPGAPGSGAQAGPGGDTWGAITTEQRTDPANSQKASPKKMPKSGGKSRGPGGSCEFCGKHFTNSSNLTVHRRSHTGERPYTCEFCNYACAQSSKLNRHRRMHGMTPGSTRFECPHCHVPFGLRATLDKHLRQKHPEAAGEA", "length": 475 }, "evidence": [ { "id": "E1BA69", "url": "https://omabrowser.org/oma/group/E1BA69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BA69", "url": "https://www.uniprot.org/uniprotkb/E1BA69" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BA69", "url": "https://www.uniprot.org/uniprotkb/E1BA69" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BA69", "url": "https://www.uniprot.org/uniprotkb/E1BA69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BA69", "url": "https://www.uniprot.org/uniprotkb/E1BA69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BA69", "url": "https://www.uniprot.org/uniprotkb/E1BA69" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BA69", "url": "https://www.uniprot.org/uniprotkb/E1BA69" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "E1BA69", "url": "https://www.uniprot.org/uniprotkb/E1BA69" } ], "pmid": "" }, { "name": "negative regulation of dendrite development", "id": "GO:2000171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000171", "evidence": [ { "database": "UniProtKB", "id": "E1BA69", "url": "https://www.uniprot.org/uniprotkb/E1BA69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BA69-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 474, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BA69-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BA69" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA69" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 177, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 396, "end_pos": 398 }, { "start_pos": 399, "end_pos": 401 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BA84-1", "uniprot_ac": "E1BA84", "uniprot_id": "E1BA84_BOVIN", "mass": { "chemical_mass": 70934.0, "monoisotopic_mass": 70934.0 }, "refseq": { "ac": "NP_001178958", "name": "ETS-related transcription factor Elf-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178958" }, "gene_names": [ { "name": "ELF4", "type": "recommended", "evidence": [ { "id": "E1BA84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ] }, { "name": "ELF4", "type": "synonym", "evidence": [ { "id": "NP_001178958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178958" } ] } ], "protein_names": [ { "name": "E74 like ETS transcription factor 4", "type": "synonym", "evidence": [ { "id": "E1BA84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA84/entry#names_and_taxonomy" } ] }, { "name": "ETS-related transcription factor Elf-4", "type": "synonym", "evidence": [ { "id": "NP_001178958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178958" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ELF4", "url": "https://www.uniprot.org/uniprotkb/E1BA84", "locus": { "chromosome": "X", "start_pos": 14045246, "end_pos": 14056197, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019061", "url": "https://www.ensembl.org/id/ENSBTAG00000019061" } ] } } ], "crossref": [ { "id": "ENSBTAG00000019061", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019061", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "504514", "url": "https://www.ncbi.nlm.nih.gov/gene/504514", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504514", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504514", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DDQEGHC", "url": "https://omabrowser.org/oma/group/DDQEGHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BA84", "url": "https://www.orthodb.org/?gene=E1BA84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12310", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12310", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178958", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178958", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BA84-1", "url": "https://www.uniprot.org/uniprotkb/E1BA84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVALQPSDLIFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPELLHLYSGLELDDVHNGIITDGTLCMTQDQILEGSFLLADDNETTSQTVSTPEVLLNVESPNNILDDKQIFSTSEMLPEPDPAPAMTLPNYLFPVSEPDALNRAGNTGDQEENCLEEKVPREESAKKTGKSKKRIRKTKGNRSTSPVTDLSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIEDEDERSEVTATSPQASAPSTSSGGSSRRASSRVSSRAAPQGKGDTSWEKPKVQHVGLQPSASLELGLSIDEEIPTTSAMLVSPPESQAKVTKAVSTSAVPSSIHLGVAPVRSGSALTLQTIPLTTVLTNGPPASTTASTQLVLQSVPPASTFKDTFTLQTSFPLNTSFQENQVAAPGAPLILSGLPQLLAGANRPTNPAPPSVMGAGPAGPSSQAPGTVIAAFIRTSGATTAPGVKEGPLRPSSYVQGMMTGAPMEGLLVSEETLRELLREQAHLQPLPSQVVSRASHNPSLLGNQTLSPPSRPTVGLTPVAELELSSSSGSLFTAEPNVSTPGSLLTRSPTPASISPFNPTSLIKMEPHDM", "length": 662, "header": "tr|E1BA84-1|E1BA84_BOVIN Isoform 1 of E74 like ETS transcription factor 4 OS=Bos taurus OX=9913 GN=ELF4 PE=3 SV=1 CANONICAL=E1BA84-1" }, "isoforms": [ { "isoform_ac": "E1BA84-1", "url": "https://www.uniprot.org/uniprotkb/E1BA84/entry#E1BA84-1", "sequence": { "sequence": "MAVALQPSDLIFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPELLHLYSGLELDDVHNGIITDGTLCMTQDQILEGSFLLADDNETTSQTVSTPEVLLNVESPNNILDDKQIFSTSEMLPEPDPAPAMTLPNYLFPVSEPDALNRAGNTGDQEENCLEEKVPREESAKKTGKSKKRIRKTKGNRSTSPVTDLSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIEDEDERSEVTATSPQASAPSTSSGGSSRRASSRVSSRAAPQGKGDTSWEKPKVQHVGLQPSASLELGLSIDEEIPTTSAMLVSPPESQAKVTKAVSTSAVPSSIHLGVAPVRSGSALTLQTIPLTTVLTNGPPASTTASTQLVLQSVPPASTFKDTFTLQTSFPLNTSFQENQVAAPGAPLILSGLPQLLAGANRPTNPAPPSVMGAGPAGPSSQAPGTVIAAFIRTSGATTAPGVKEGPLRPSSYVQGMMTGAPMEGLLVSEETLRELLREQAHLQPLPSQVVSRASHNPSLLGNQTLSPPSRPTVGLTPVAELELSSSSGSLFTAEPNVSTPGSLLTRSPTPASISPFNPTSLIKMEPHDM", "length": 662, "header": "tr|E1BA84-1|E1BA84_BOVIN Isoform 1 of E74 like ETS transcription factor 4 OS=Bos taurus OX=9913 GN=ELF4 PE=3 SV=1 CANONICAL=E1BA84-1" }, "locus": { "chromosome": "X", "start_pos": 14056135, "end_pos": 14045661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025376.6", "url": "https://www.ensembl.org/id/ENSBTAT00000025376.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025376.4", "url": "https://www.ensembl.org/id/ENSBTAP00000025376.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 632, "start_aa": "Thr", "end_pos": 632, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr632", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 642, "start_aa": "Thr", "end_pos": 642, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr642", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:504514", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504514", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZWM8-1", "protein_name": "E74 like ETS transcription factor 4", "gene_name": "Elf4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIALQPSDLVFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPELVHLYSGLDLDEVHSGIIRDRTLCMTQDQILEGSILLTDDNVSTSNNSSSTEVLFNVATPSDVLDEKQIFSTPEVLPDSNSVQAINLPNFLLSTPEPDDPKKTSDAGDQKEYSLEEVSREENLRKIGKSRKRNRKTKNNRSTSPVTDPSVPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIDDEEESTETPEDSSQASTSSTPSTSTTRRPSSRVVTRASPEDKDSPSWEKPKVEHTGLQPSASLELGLSVDEEVPTTSTMIVSPLQSQAKPAKTVSTSAPSNIHLGVAPVGPGSTVTLQTIPLTTVLTNGPPAGTTAPAQLVLQSVPQVSTFKDTLTLQTSFPLNASLQENQVATQGTPLILSGLPQLLAGANHQSNPVTSQVIGAGSAGPSSQPPGTVIAAFIRTSNGTSVPVVKEGPLRSSSYVQGVVTGAPVEGLLVPEETLRELLRDQAHLQPLQSQALSRGSHNLSLVGNQTLSPPSHPTVGLTPVAELELSSSSGSLLVTEPNMTTSGSLLTRSPTQAPFSPFNPTSLIKMEPHDI", "length": 660 }, "evidence": [ { "id": "E1BA84", "url": "https://omabrowser.org/oma/group/E1BA84/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RTH4-1", "protein_name": "E74 like ETS transcription factor 4", "gene_name": "ELF4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAITLQPSDLIFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPELLHLYSGLELDDVHNGIITDGTLCMTQDQILEGSFLLTDDNEATSQTMSTTEVLLNVESPSDILDEKQIFSTSEMLPDPEPAPAVTLPNYLFPVSEPDALNRAGDTGDQEEHCLKEKVPREDSAKKTGKSKKRIRKTKGNRSTSPVTDPSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIEDEDERSEVTAASPQASTPSTSSAGSTRRASARVSSRAAPPGKGGTSWEKPKVQQHVGLQPSASLESGPSPDEEMPTTSTVLVSPPESQAKLTKAVSTSVPSNIHLGVAPVGSGSALTLQTIPLTTVLTNGPPASTTASTQLVLQSVPPASTFKDTFTLQASFPLNTSFQENQVAAPGAPLILSGLPQLLAGTNRPNNPAPPSVTGAGPAGPSSQPPGTVIAAFIRTSGATAAPGVKEGPLRPSSYVQGVMTGAPMEGLLVPEETLRELLRDQAHLQPLPTQVVSRGSHNPSLLGNQTLSPPSHPTVGLTPVAELELSSGSGSLFMAEPSVATSGSLLTRSPTPAPFSPFNPTSLIKMEPHDI", "length": 662 }, "evidence": [ { "id": "E1BA84", "url": "https://omabrowser.org/oma/group/E1BA84/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q99607-1", "protein_name": "ETS-related transcription factor Elf-4", "gene_name": "ELF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAITLQPSDLIFEFASNGMDDDIHQLEDPSVFPAVIVEQVPYPDLLHLYSGLELDDVHNGIITDGTLCMTQDQILEGSFLLTDDNEATSHTMSTAEVLLNMESPSDILDEKQIFSTSEMLPDSDPAPAVTLPNYLFPASEPDALNRAGDTSDQEGHSLEEKASREESAKKTGKSKKRIRKTKGNRSTSPVTDPSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIEDEDESSEATAAPPQASTASVASASTTRRTSSRVSSRSAPQGKGSSSWEKPKIQHVGLQPSASLELGPSLDEEIPTTSTMLVSPAEGQVKLTKAVSASSVPSNIHLGVAPVGSGSALTLQTIPLTTVLTNGPPASTTAPTQLVLQSVPAASTFKDTFTLQASFPLNASFQDSQVAAPGAPLILSGLPQLLAGANRPTNPAPPTVTGAGPAGPSSQPPGTVIAAFIRTSGTTAAPRVKEGPLRSSSYVQGMVTGAPMEGLLVPEETLRELLRDQAHLQPLPTQVVSRGSHNPSLLGNQTLSPPSRPTVGLTPVAELELSSGSGSLLMAEPSVTTSGSLLTRSPTPAPFSPFNPTSLIKMEPHDI", "length": 663 }, "evidence": [ { "id": "E1BA84", "url": "https://omabrowser.org/oma/group/E1BA84/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2U4-1", "protein_name": "ETS-related transcription factor Elf-4", "gene_name": "Elf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIALQPSDLVFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPELVHLCSGLDLDEVHNGIIRDRTLCMTQDQILEGSILLTDDDVSTSNNVSSTEVLFNVATPSDVLDEKQIFSSPEVLSDSNSVQAINLPNFLLSTPEPDDLKKTSDAGDQKEHSEEEKVSREENLRKMGKARKRNRKTKNNRSTSPVTDPSMPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIDDEEESPETPEDSSQASTSSTPSTSTIRRASSRVGTRASPEDKDNPPWEKPKVQHTGLQPSASLELGLSVDEEVPTTSTMLASPLQSQARLTKTVSSSPAPSNIHLGVAPVGPGSTVTLQTIPLTTVLTNGPPASTTAPTQLVLQSVPQVSTFKDTFTLQTSFPLNTNLQENQVATQGAPLILSGLPQLLAGANPQSNPAPSQVIGAGSAGPSSQPPGTVIAAFIRTSSGTSVPVVKEGPLRSSSYVQGVVTGAPVEGLLVPEETLRELLRDQGHLQPLPSQVLSRGSHNLSLVGNQTLSPPSHPTVGLTPVAELELSSGSGPLFVTEPSVTRSPTQAPFSPFNPTSLIKMEPQDI", "length": 655 }, "evidence": [ { "id": "E1BA84", "url": "https://omabrowser.org/oma/group/E1BA84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1 beta production", "id": "GO:0032691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032691", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" }, { "name": "negative regulation of interleukin-6 production", "id": "GO:0032715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor production", "id": "GO:0032720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032720", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" }, { "name": "natural killer cell proliferation", "id": "GO:0001787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001787", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" }, { "name": "NK T cell proliferation", "id": "GO:0001866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001866", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BA84", "url": "https://www.uniprot.org/uniprotkb/E1BA84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BA84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA84" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 208, "end_pos": 290, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 632, 642 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 629, "end_pos": 631 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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{ "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BAA1-1", "uniprot_ac": "E1BAA1", "uniprot_id": "E1BAA1_BOVIN", "mass": { "chemical_mass": 36624.0, "monoisotopic_mass": 36624.0 }, "refseq": { "ac": "XP_002697139", "name": "receptor-transporting protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697139" }, "gene_names": [ { "name": "RTP3", "type": "recommended", "evidence": [ { "id": "E1BAA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAA1" } ] }, { "name": "RTP3", "type": "synonym", "evidence": [ { "id": "XP_002697139", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697139" } ] } ], "protein_names": [ { "name": "Receptor transporter protein 3", "type": "synonym", "evidence": [ { "id": "E1BAA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAA1/entry#names_and_taxonomy" } ] }, { "name": "receptor-transporting protein 3", "type": "synonym", "evidence": [ { "id": "XP_002697139", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697139" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BAA1", "url": "https://www.uniprot.org/uniprotkb/E1BAA1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RTP3", "url": "https://www.uniprot.org/uniprotkb/E1BAA1", "locus": { "chromosome": "22", "start_pos": 52926963, "end_pos": 52930809, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018767", "url": "https://www.ensembl.org/id/ENSBTAG00000018767" } ] } } ], "crossref": [ { "id": "E1BAA1", "url": "https://alphafold.ebi.ac.uk/entry/E1BAA1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018767", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018767", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618086", "url": "https://www.ncbi.nlm.nih.gov/gene/618086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618086", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSQPSFE", "url": "https://omabrowser.org/oma/group/CSQPSFE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BAA1", "url": "https://www.orthodb.org/?gene=E1BAA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14402", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14402", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14402:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14402:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13695", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13695", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002697139", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697139", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BAA1", "url": "https://www.uniprot.org/uniprotkb/E1BAA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAA1-1", "url": "https://www.uniprot.org/uniprotkb/E1BAA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLSWVGTPMLAPGRRHCHTQLTAMAEMAEMDLDMKVWKRVFQELIQEVKPCHTWQLTLDKSLLPNILKPGWAQYQQRTFARFQCSLCSRNWASAQVQVLFHMHWSEGESRGQVKMRVFAQRCQKCSQPSFEVPEFTEENISRILNNLVLQILKKCYREGIKFVNSPMIKAIALKGPHNSDNCEACLQGVCVQNDIGLAVQSPVALSFPTVSSPTLGITAEMPSPTSGSTRGEAVMKKKVLPRSWFPEPTPAESLPTSWSPRMNTSFQRERRDQDSSCDQSFYSHPAQHPRSTGIGCCCFILTLIVIIIIIVAVIVVAVTIRASKA", "length": 326, "header": "tr|E1BAA1-1|E1BAA1_BOVIN Isoform 1 of Receptor transporter protein 3 OS=Bos taurus OX=9913 GN=RTP3 PE=4 SV=2 CANONICAL=E1BAA1-1" }, "isoforms": [ { "isoform_ac": "E1BAA1-1", "url": "https://www.uniprot.org/uniprotkb/E1BAA1/entry#E1BAA1-1", "sequence": { "sequence": "MTLSWVGTPMLAPGRRHCHTQLTAMAEMAEMDLDMKVWKRVFQELIQEVKPCHTWQLTLDKSLLPNILKPGWAQYQQRTFARFQCSLCSRNWASAQVQVLFHMHWSEGESRGQVKMRVFAQRCQKCSQPSFEVPEFTEENISRILNNLVLQILKKCYREGIKFVNSPMIKAIALKGPHNSDNCEACLQGVCVQNDIGLAVQSPVALSFPTVSSPTLGITAEMPSPTSGSTRGEAVMKKKVLPRSWFPEPTPAESLPTSWSPRMNTSFQRERRDQDSSCDQSFYSHPAQHPRSTGIGCCCFILTLIVIIIIIVAVIVVAVTIRASKA", "length": 326, "header": "tr|E1BAA1-1|E1BAA1_BOVIN Isoform 1 of Receptor transporter protein 3 OS=Bos taurus OX=9913 GN=RTP3 PE=4 SV=2 CANONICAL=E1BAA1-1" }, "locus": { "chromosome": "22", "start_pos": 52930665, "end_pos": 52927967, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024988.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024988.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024988.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024988.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 226, "start_aa": "Thr", "end_pos": 226, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr226", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:618086", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618086", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BAA1", "url": "https://www.uniprot.org/uniprotkb/E1BAA1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BAA1", "url": "https://www.uniprot.org/uniprotkb/E1BAA1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BAA1", "url": "https://www.uniprot.org/uniprotkb/E1BAA1" } ], "pmid": "" }, { "name": "olfactory receptor binding", "id": "GO:0031849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031849", "evidence": [ { "database": "UniProtKB", "id": "E1BAA1", "url": "https://www.uniprot.org/uniprotkb/E1BAA1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { 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"Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BAB2", "url": "https://www.uniprot.org/uniprotkb/E1BAB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAB2-1", "url": "https://www.uniprot.org/uniprotkb/E1BAB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFSPLKVAVVCMSNMNRSMEAHSILRKKGFSVRSFGAGSRVRLPGTARNLPVVYDFSTTYEQMRKDLVRIDRERYTSNGILHILGRNERIKPRPERFQECRDRFDVIFTCEESVYDRVIEELWVREQETCQPVYVINVNMDDNTEDATLGSLIICELCERLQQAEDMEGSLAELLLAVERKTGRSFLHTVCFY", "length": 194, "header": "tr|E1BAB2-1|E1BAB2_BOVIN Isoform 1 of RNA polymerase II subunit A C-terminal domain phosphatase SSU72 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BAB2-1" }, "isoforms": [ { "isoform_ac": "E1BAB2-1", "url": "https://www.uniprot.org/uniprotkb/E1BAB2/entry#E1BAB2-1", "sequence": { "sequence": 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"https://omabrowser.org/oma/group/E1BAB2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "E1BAB2", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "termination of RNA polymerase II transcription", "id": "GO:0006369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006369", "evidence": [ { "database": "UniProtKB", "id": "E1BAB2", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "E1BAB2", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA polymerase II CTD heptapeptide repeat phosphatase activity", "id": "GO:0008420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008420", "evidence": [ { "database": "UniProtKB", "id": "E1BAB2", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEW5-1", "A0AAA9TV14-1", "A0AAA9S745-1", "A0A3Q1MV48-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "F1MBQ1-1", "A0AAA9RTM1-1", "A0AAF6YJP2-1", "P48452-1", "F1MI99-1", "G3N3B3-1", "O62830-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "A6H772-1", "O62829-1", "P61287-1", "A0AAA9U0H6-1", "Q3ZBF9-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q0P594-1", "Q1RMV9-1", "Q2KJ36-1", "Q2PC20-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0A3Q1N224-1", "E1BMD4-1", "A0AAF6DLF7-1", "F1N580-1", "F1MQM7-1", "F1MW60-1", "F1N719-1", "E1BF95-1", "E1BIE7-1", "F1MEZ2-1", "F1MM08-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLF7-1", "F1MI92-1", 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"gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1MLC5", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] } ] }, { "uniprot_ac": "A0A3Q1MV48", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] } ] }, { "uniprot_ac": "A0A3Q1MZU1", "gene_name": "CTDSPL2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] } ] }, { "uniprot_ac": "A0A3Q1N224", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] } ] }, { "uniprot_ac": "A0A3Q1N5B2", "gene_name": "CDC14B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S454", "gene_name": "LOC112441581", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S454" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S454" } ] } ] }, { "uniprot_ac": "A0AAA9S745", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] } ] }, { "uniprot_ac": "A0AAA9SCR0", "gene_name": "LOC112441582", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SCR0", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0AAA9TD32" } ] } ] }, { "uniprot_ac": "A0AAA9TT76", "gene_name": "PPP3CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT76" } ] } ] }, { "uniprot_ac": "A0AAA9TV14", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TV14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TV14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ] } ] 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"A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YJP2", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] } ] }, { "uniprot_ac": "A0ABI0P1A3", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0ABI0P1A3", "database": "UniProtKB", "url": 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"activity": "", "evidence": [ { "id": "A6H772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H772" } ] } ] }, { "uniprot_ac": "E1B9Y5", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] } ] }, { "uniprot_ac": "E1BAB2", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] } ] }, { "uniprot_ac": "E1BBD9", "gene_name": "LOC112445820", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] } ] }, { "uniprot_ac": "E1BEW5", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] } ] }, { "uniprot_ac": "E1BF95", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] } ] }, { "uniprot_ac": "E1BIE7", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] } ] }, { "uniprot_ac": "E1BIZ2", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] } ] }, { "uniprot_ac": "E1BMD4", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] } ] }, { "uniprot_ac": "F1MBQ1", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MI92", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MW60", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1N580", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] } ] }, { "uniprot_ac": "F1N719", "gene_name": "PPP5C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] } ] }, { "uniprot_ac": "F6RRD7", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] } ] }, { "uniprot_ac": "G3N3B3", "gene_name": "PPM1N", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] } ] }, { "uniprot_ac": "O62829", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] } ] }, { "uniprot_ac": "O62830", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62830" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62830" } ] } ] }, { "uniprot_ac": "P0C591", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] } ] }, { "uniprot_ac": "P48452", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48452" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48452" } ] } ] }, { "uniprot_ac": "P61287", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P61287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61287" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P61287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61287" } ] } ] }, { "uniprot_ac": "P67774", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P67774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67774" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P67774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67774" } ] } ] }, { "uniprot_ac": "P79126", "gene_name": "PPM1G", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P79126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79126" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P79126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79126" } ] } ] }, { "uniprot_ac": "Q0IID7", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": 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Classification" ] }, { "id": "IPR050394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BAC5", "url": "https://www.orthodb.org/?gene=E1BAC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24340:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24340:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BAC5", "url": "https://www.uniprot.org/uniprotkb/E1BAC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAC5-1", "url": "https://www.uniprot.org/uniprotkb/E1BAC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPPPFPALPQGQARCQPRRRRKPGPAGGGHRSPPKMLFFVHGVRLSGPPIGAASRAAPRFQIYPAPASFPCSAMATSGRLSFTVRRLLDLPEQDAQHLRKREPELSAPEPGPCATWLESERGHYPSSDESSPEASPRDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRARAPGVAEAPDLAAAAEVRAAPGLLRRVVVPVLVRDGQPCGGSAEGGTAAARDKSAAPPAAACPVPGYAAFGPGSAFGLFPAYQHLAPPALVSWNW", "length": 311, "header": "tr|E1BAC5-1|E1BAC5_BOVIN Isoform 1 of NK2 homeobox 8 OS=Bos taurus OX=9913 GN=NKX2-8 PE=3 SV=2 CANONICAL=E1BAC5-1" }, "isoforms": [ { "isoform_ac": "E1BAC5-1", "url": "https://www.uniprot.org/uniprotkb/E1BAC5/entry#E1BAC5-1", "sequence": { "sequence": "MSPPPFPALPQGQARCQPRRRRKPGPAGGGHRSPPKMLFFVHGVRLSGPPIGAASRAAPRFQIYPAPASFPCSAMATSGRLSFTVRRLLDLPEQDAQHLRKREPELSAPEPGPCATWLESERGHYPSSDESSPEASPRDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRARAPGVAEAPDLAAAAEVRAAPGLLRRVVVPVLVRDGQPCGGSAEGGTAAARDKSAAPPAAACPVPGYAAFGPGSAFGLFPAYQHLAPPALVSWNW", "length": 311, "header": "tr|E1BAC5-1|E1BAC5_BOVIN Isoform 1 of NK2 homeobox 8 OS=Bos taurus OX=9913 GN=NKX2-8 PE=3 SV=2 CANONICAL=E1BAC5-1" }, "locus": { "chromosome": "21", "start_pos": 46769737, "end_pos": 46767839, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017757.5", "url": "https://www.ensembl.org/id/ENSBTAT00000017757.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017757.4", "url": "https://www.ensembl.org/id/ENSBTAP00000017757.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BAC5", "url": "https://www.uniprot.org/uniprotkb/E1BAC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BAC5", "url": "https://www.uniprot.org/uniprotkb/E1BAC5" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BAC5", "url": "https://www.uniprot.org/uniprotkb/E1BAC5" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "E1BAC5", "url": "https://www.uniprot.org/uniprotkb/E1BAC5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BAC5", "url": "https://www.uniprot.org/uniprotkb/E1BAC5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BAC5", "url": "https://www.uniprot.org/uniprotkb/E1BAC5" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BAC5", "url": "https://www.uniprot.org/uniprotkb/E1BAC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BAC5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BAC5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BAC5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BAC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAC5" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 156, "end_pos": 216, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BAC7-1", "uniprot_ac": "E1BAC7", "uniprot_id": "E1BAC7_BOVIN", "mass": { "chemical_mass": 35140.0, "monoisotopic_mass": 35140.0 }, "refseq": { "ac": "XP_002688382", "name": "sulfotransferase 1 family member D1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688382" }, "gene_names": [ { "name": "SULT1D1", "type": "recommended", "evidence": [ { "id": "E1BAC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAC7" } ] }, { "name": "SULT1D1", "type": "synonym", "evidence": [ { "id": "XP_002688382", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688382" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "E1BAC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAC7/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "E1BAC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAC7/entry#names_and_taxonomy" } ] }, { "name": "sulfotransferase 1 family member D1", "type": "synonym", "evidence": [ { "id": "XP_002688382", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688382" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BAC7", "url": "https://www.uniprot.org/uniprotkb/E1BAC7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SULT1D1", "url": "https://www.uniprot.org/uniprotkb/E1BAC7", "locus": {} } ], "crossref": [ { "id": "E1BAC7", "url": "https://alphafold.ebi.ac.uk/entry/E1BAC7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000038214", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038214", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100297614", "url": "https://www.ncbi.nlm.nih.gov/gene/100297614", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100297614", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100297614", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IAEEWSQ", "url": "https://omabrowser.org/oma/group/IAEEWSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BAC7", "url": "https://www.orthodb.org/?gene=E1BAC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11783", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11783", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002688382", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688382", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "70607", "url": "https://www.rhea-db.org/rhea/70607", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BAC7", "url": "https://www.uniprot.org/uniprotkb/E1BAC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAC7-1", "url": "https://www.uniprot.org/uniprotkb/E1BAC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSKLDIFRRELVDVQGIPLFWSIVEEWSQVESFENRPDDLLIATYPKSGTTWISEILDLIYNHGDVEKCKRDAIYKRVPFMELIIPRLTNGVEDLNDMQSPRLVKKHLPVQLLPSSFWKNNCKMVYVARNANDVAVSYYYFYQMAKMHPDPGTWEEFLDKFMTGKVAFGSWYDHVKGWWEKKKDYCKLYLFYEDMKQDPKCEIQKLLKFLDKDLPEETVDKILYHSSFDMMKQNPSANYTTMPKFCMDHSVSPFMRKGVSGDWKNQFTVVQYERFEEDYEKKMKGSTLQFHSEI", "length": 295, "header": "tr|E1BAC7-1|E1BAC7_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=SULT1D1 PE=3 SV=3 CANONICAL=E1BAC7-1" }, "isoforms": [ { "isoform_ac": "E1BAC7-1", "url": "https://www.uniprot.org/uniprotkb/E1BAC7/entry#E1BAC7-1", "sequence": { "sequence": "MDSKLDIFRRELVDVQGIPLFWSIVEEWSQVESFENRPDDLLIATYPKSGTTWISEILDLIYNHGDVEKCKRDAIYKRVPFMELIIPRLTNGVEDLNDMQSPRLVKKHLPVQLLPSSFWKNNCKMVYVARNANDVAVSYYYFYQMAKMHPDPGTWEEFLDKFMTGKVAFGSWYDHVKGWWEKKKDYCKLYLFYEDMKQDPKCEIQKLLKFLDKDLPEETVDKILYHSSFDMMKQNPSANYTTMPKFCMDHSVSPFMRKGVSGDWKNQFTVVQYERFEEDYEKKMKGSTLQFHSEI", "length": 295, "header": "tr|E1BAC7-1|E1BAC7_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=SULT1D1 PE=3 SV=3 CANONICAL=E1BAC7-1" }, "locus": { "chromosome": "6", "start_pos": 85281712, "end_pos": 85256042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055587.4", "url": "https://www.ensembl.org/id/ENSBTAT00000055587.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048913.3", "url": "https://www.ensembl.org/id/ENSBTAP00000048913.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100297614", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100297614", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BPX1-1", "protein_name": "Sulfotransferase", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDNKQDIFRRDLVDFQGVPLFWSITEEWSQVESFESRPDDLLISTYPKSGTTWTSEILDLIYNNGDVEKCKRDAIYKRVPFMELIVPGLSNGVKELNDMQSPRLVKTHLPVQLLPSSFWKNNCKIVYVARNAKDVAVSYYYFYQMAKIHPEPGTWEEFLDKFIAGKVAFGSWYDHVKGWWEKRKDHRILYLFFEDMKKDPKCEIQKLLKFLDKDLPEETVDKILYHSSFDMMKQNPSANYTTLPKFSMDHSLSPFMRKGISGDWKNQFTVAQYERFEEDYKKKMKGSTLQFCSEI", "length": 295 }, "evidence": [ { "id": "E1BAC7", "url": "https://omabrowser.org/oma/group/E1BAC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F197-1", "protein_name": "Sulfotransferase", "gene_name": "LOC100763252", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDKKLDIFRRELVDVHGIPLFWSIAEQWSQVESFEARPDDLLISTYPKSGTTWISEILDLIYNNGDAEKCKRDAIYKRVPFMELIIPGLSNGVELLKNMHSPRLVKTHLPVQLLPSSFWKNDCKMVYVARNAKDVAVSYYYFYQMAKIHPEPGTWEEFLDKFMAGQVGFGSWYDHVKGWWEKRNDYRILYLFYEDMKEDPKYEIQKLLKFLEKDMPEEIVNKILYHSSFNVMKENPNANYTTMKKEEMDHAVSPFMRKGISGDWKNQFTVAQYEKFEDDYVKKMKESTLKFRSEI", "length": 295 }, "evidence": [ { "id": "E1BAC7", "url": "https://omabrowser.org/oma/group/E1BAC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1NMA2-1", "protein_name": "Sulfotransferase", "gene_name": "SULT1E1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGNDEVIRQDLGCLYDIPLYKCFVAGWPQVEAFQARPDDLLIATYPKSGTTWLSEILDAIYHDGDLEKCRRDAIYNRVPFLEMKAPGILSGVEQLEKIPSPRLVKTHLPVHLLPASFQEKDCKVIYMARNAKDVVISYYYFYQMAKIHPDPGTLSEFLQAFMDGKVAYGSWYKHVKGWWEKRHEKRLLYLFYEDMKKDPRREIQKILQFLGKEVAEETVARILHHTSFQEMKKNPATNYETMPTELMDHSLSPFMRKGISGDWANHFTVAQNERFDQHYQQQMAGSDLCFQMEA", "length": 294 }, "evidence": [ { "id": "E1BAC7", "url": "https://omabrowser.org/oma/group/E1BAC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3V9R3-1", "protein_name": "Sulfotransferase 1 family member D1", "gene_name": "Sult1d1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"https://alphafold.ebi.ac.uk/entry/E1BAI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013984", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013984", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "784635", "url": "https://www.ncbi.nlm.nih.gov/gene/784635", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:784635", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784635", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RKPHCVD", "url": "https://omabrowser.org/oma/group/RKPHCVD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BAI2", "url": "https://www.orthodb.org/?gene=E1BAI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10353:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10353:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00232", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-109704", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-109704", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1257604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-190374", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-190374", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5654219", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654219", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5654687", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654687", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5654688", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654688", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5654689", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5654693", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654693", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5654726", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654726", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6811558", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178124", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178124", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BAI2", "url": "https://www.uniprot.org/uniprotkb/E1BAI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAI2-1", "url": "https://www.uniprot.org/uniprotkb/E1BAI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPARAPPRRLRAFPPPPPPLWLLLLALGGRPLRAEPGDGAQTWARFARPPTPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHRPPAPPGDPSAAGWPSGAPSPPPPATGDVASDGYNNVFRDTEGLRELGVTHYRFSISWARVLPNGSASAPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSPRLGYLVAHNLLLAHAKIWHLYDTSFRPTQGGQVSIALSSHWISPRRMTEHSIQECQKSLDFVLGWFAKPIFIDGDYPESMKNNLSSLLPDFTESEKKFIKGTADFFALSFGPTLSFQLLDPQMKFRQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKKLLPKSSALFYQKLIENNGFPPLPENQPLEGTFPCDFAWGVVDNCIQVDTTLSQFIDPNVYLWDVHRSKRLIKVDGVLTKTRKSYCVDFAAIRPQIALLQEMHVTHFHFSLDWALILPLGNRSQVNRTVLGFYRCVASELVRANITPVVALWRPAAPHQGLPAPLARHGAWENPHTALAFAEYASLCFQDLGRHVKFWITMHEPSTRNMTYSAGHNLLKAHALAWRTYDERFRRSQKGKISIALQADWIEPACPFSPEDREVAERVLEFDIGWLAEPIFGSGDYPRVMRDWLNQRNNFLLPYFTDEEKKLIRGSFDFLALSHYTTILVDWEKEDPIKYNDYLAVQEMTDITWLNSPSQVAVVPWGLRKVLNWLKAKYGDLPMYIISNGIDDDPHAAQDNLRVYYMQTYVNEALKAYILDGINLCGYFAYSFNDRTAPKFGLYRYAANQFEPKPSMKHYRKIIDNNGFPGPETLGRFCPEEFTLCTECSFFHTRKSLLAFIAFLLFAFVISLSLIFYYSKKGRRGYK", "length": 1013, "header": "tr|E1BAI2-1|E1BAI2_BOVIN Isoform 1 of Klotho OS=Bos taurus OX=9913 GN=KL PE=3 SV=3 CANONICAL=E1BAI2-1" }, "isoforms": [ { "isoform_ac": "E1BAI2-1", "url": "https://www.uniprot.org/uniprotkb/E1BAI2/entry#E1BAI2-1", "sequence": { "sequence": "MPARAPPRRLRAFPPPPPPLWLLLLALGGRPLRAEPGDGAQTWARFARPPTPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHRPPAPPGDPSAAGWPSGAPSPPPPATGDVASDGYNNVFRDTEGLRELGVTHYRFSISWARVLPNGSASAPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSPRLGYLVAHNLLLAHAKIWHLYDTSFRPTQGGQVSIALSSHWISPRRMTEHSIQECQKSLDFVLGWFAKPIFIDGDYPESMKNNLSSLLPDFTESEKKFIKGTADFFALSFGPTLSFQLLDPQMKFRQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKKLLPKSSALFYQKLIENNGFPPLPENQPLEGTFPCDFAWGVVDNCIQVDTTLSQFIDPNVYLWDVHRSKRLIKVDGVLTKTRKSYCVDFAAIRPQIALLQEMHVTHFHFSLDWALILPLGNRSQVNRTVLGFYRCVASELVRANITPVVALWRPAAPHQGLPAPLARHGAWENPHTALAFAEYASLCFQDLGRHVKFWITMHEPSTRNMTYSAGHNLLKAHALAWRTYDERFRRSQKGKISIALQADWIEPACPFSPEDREVAERVLEFDIGWLAEPIFGSGDYPRVMRDWLNQRNNFLLPYFTDEEKKLIRGSFDFLALSHYTTILVDWEKEDPIKYNDYLAVQEMTDITWLNSPSQVAVVPWGLRKVLNWLKAKYGDLPMYIISNGIDDDPHAAQDNLRVYYMQTYVNEALKAYILDGINLCGYFAYSFNDRTAPKFGLYRYAANQFEPKPSMKHYRKIIDNNGFPGPETLGRFCPEEFTLCTECSFFHTRKSLLAFIAFLLFAFVISLSLIFYYSKKGRRGYK", "length": 1013, "header": "tr|E1BAI2-1|E1BAI2_BOVIN Isoform 1 of Klotho OS=Bos taurus OX=9913 GN=KL PE=3 SV=3 CANONICAL=E1BAI2-1" }, "locus": { "chromosome": "12", "start_pos": 28088332, "end_pos": 28052269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018586.6", "url": "https://www.ensembl.org/id/ENSBTAT00000018586.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018586.5", "url": "https://www.ensembl.org/id/ENSBTAP00000018586.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 51, "start_aa": "Thr", "end_pos": 51, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr51", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:784635", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784635", "resource": "KEGG Pathway" }, { "id": "R-BTA-109704", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-109704", "resource": "Reactome", "description": "PI3K Cascade" }, { "id": "R-BTA-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-BTA-190374", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-190374", "resource": "Reactome", "description": "FGFR1c and Klotho ligand binding and activation" }, { "id": "R-BTA-5654219", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654219", "resource": "Reactome", "description": "Phospholipase C-mediated cascade: FGFR1" }, { "id": "R-BTA-5654687", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654687", "resource": "Reactome", "description": "Downstream signaling of activated FGFR1" }, { "id": "R-BTA-5654688", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654688", "resource": "Reactome", "description": "SHC-mediated cascade:FGFR1" }, { "id": "R-BTA-5654689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654689", "resource": "Reactome", "description": "PI-3K cascade:FGFR1" }, { "id": "R-BTA-5654693", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654693", "resource": "Reactome", "description": "FRS-mediated FGFR1 signaling" }, { "id": "R-BTA-5654726", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654726", "resource": "Reactome", "description": "Negative regulation of FGFR1 signaling" }, { "id": "R-BTA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-BTA-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XR32-1", "protein_name": "Klotho", "gene_name": "KL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPPPPPVLPVLPVLLVLLGLGRPLLGAPGQGAGTWARFAHLPYPQDQLFLHDTFPDGFLWGAGSAAYQTEGGWRQGGKGASIWDTFTHRPTTPAGSILPGPTGGDVASDSYNNIFRDIEGLRHLGVSHYRFSLAWTRLMPNGTAPVNPVGLAHYSQVLSRLQELGIEPIVTLYHWDLPQGLQDAFGGWASPVLPNLFHDYAELCFRHFGGQVRYWLTMDNPYVVAWHGYGTGRLPPGVQGGPSLGYRAAHHLLQSRCTAVGALFGTLCIVTLKAVGLHTRAHAKVWHLYNDHFRPTQKGKVSIALSSHWIKPQHMTEKNIKECQKSLDFVLGWFAKPIFINGDYPESMRSNLSSLLPEFSEEDKKYIKGTADFFALSFGATLSFQLLDSHMKFQQLESISLRQLLYWISTEYNNPPVFIVENSWFVSGSTKRDDAKYIYYLKKFIMETLKAIRYDGVNVFGYTVWSLLDGFEWHRGYSIRRGLFYVDFQSHDKKLIPKSSVLFYQKLIEKNGFPPLPENQPIAGVFPCGFAWGIVDNYIQVDTTPAQFLDPNVYVWDVHQTKKLIKVDGVFTSQRKHHCVDFAAIRLQISLLQEMHVTHFHFSLKWSSVLPLGNLSLINHTLVHYYQCFASELLRVNITPVVALWQPMAENQELPTSLAKFGAWENSETVQAFVEYAKFCFASLGDHVKFWITMNEPSVKNLTYTAGHNLLRAHAKAWHLYDKEFRRSQKGKISIALQADWVEPACPFSRNDQEVADRILEFDIGWLAEPIFGSGDYPHMMRAWLHQRNSVDLYNFHLPSFSEDEKKLIQGSFDFFALSHYTTILVGWEKEDALKYDHYLEVQMISDITWLHSPSRAAVVPWGLRKVLRWVKSKYGDVPVYVMANGIDDDQNMVHDKLRVYYIQNYINEALKAYALDNVNLQGYFVYSFNDKTAPKYGLYSYAANQYEPKPSMKHYREIIDNNGFPGPDTAEVLCPEEAAMCPECHFFRTRKSLFAFISFIFVAFIVTIFCIMYYSKRAERRYK", "length": 1025 }, "evidence": [ { "id": "E1BAI2", "url": "https://omabrowser.org/oma/group/E1BAI2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RSR6-1", "protein_name": "Klotho", "gene_name": "KL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPARAPPRRPWPPLPLPLLLLALSGRCLRAEPGDGAQTWARFARPPAPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHRPAAPLSGPPGAGLPSGVPSPTLPATGDVASDSYNNVFRDTEGLRELGVTHYRFSISWARVLPTGIASAPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGGPQLGYLVAHNLLLAHAKIWHLYNASFRPTQGGQVSIALSSHWISPRRMTDHSIKECQKSLDFVLGWFAKPVFIDGDYPESMKNNLSSLLPDFTESEKKFIKGTADFFALSFGPTLSFQLLDPQMKFHQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAVRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYIDFLSQDKKLLPKSSALFYQKLIEKNGFPPLPENQPLEGTFPCDFAWGIVDNYIQVDTTLSQFTDPNVYLWDVHRSKRLIKVDGVVTKKRKSYCVDFAAIRPQVALLQDMHVSHFHFSLDWAQILPLGNQSQVNRTVLRYYRCVASELVRANITPVVALWRPAAAAAHQGLPRPLARHGAWENPHTALAFAEYASLCFRDLGHHVKFWITMSEPSTRNMTYSAGHNLLKAHALAWRVYDEKFRRTQHGKISIALQADWIEPACPFSPKDQDVAERVLEFDIGWLAEPIFGSGDYPPVMRDWLNQRNNFLLPYFTDEEKKLIRGSFDFLAVSHYTTILVDWEKEDPTKYNDYLAVQEMTDITWLNSPSQVAVVPWGLRKVLNWLRSKYGDLPMYIISNGIDDDPQAAEDQLRVYYLQNYVNEALKAYILDDINLCGYFAYSFNDRTAPKFGLYRYAANQFEPKPSMKHYRKIIDNNGFPDPETLGRFCPEEFALCTECSFFHTRKSLLAFIAFLFFAFVISLSLIFYYSKKGRKNYK", "length": 1011 }, "evidence": [ { "id": "E1BAI2", "url": "https://omabrowser.org/oma/group/E1BAI2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35082-1", "protein_name": "Klotho", "gene_name": "Kl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLARAPPRRPPRLVLLRLLLLHLLLLALRARCLSAEPGQGAQTWARFARAPAPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHSGAAPSDSPIVVAPSGAPSPPLSSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGRVSIALSSHWINPRRMTDYNIRECQKSLDFVLGWFAKPIFIDGDYPESMKNNLSSLLPDFTESEKRLIRGTADFFALSFGPTLSFQLLDPNMKFRQLESPNLRQLLSWIDLEYNHPPIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIEDNGFPPLPENQPLEGTFPCDFAWGVVDNYVQVDTTLSQFTDPNVYLWDVHHSKRLIKVDGVVAKKRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNHTVLHFYRCMISELVHANITPVVALWQPAAPHQGLPHALAKHGAWENPHTALAFADYANLCFKELGHWVNLWITMNEPNTRNMTYRAGHHLLRAHALAWHLYDDKFRAAQKGKISIALQADWIEPACPFSQNDKEVAERVLEFDIGWLAEPIFGSGDYPRVMRDWLNQKNNFLLPYFTEDEKKLVRGSFDFLAVSHYTTILVDWEKEDPMKYNDYLEVQEMTDITWLNSPSQVAVVPWGLRKVLNWLRFKYGDLPMYVTANGIDDDPHAEQDSLRIYYIKNYVNEALKAYVLDDINLCGYFAYSLSDRSAPKSGFYRYAANQFEPKPSMKHYRKIIDSNGFLGSGTLGRFCPEEYTVCTECGFFQTRKSLLVFISFLVFTFIISLALIFHYSKKGQRSYK", "length": 1014 }, "evidence": [ { "id": "E1BAI2", "url": "https://omabrowser.org/oma/group/E1BAI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UEF7-1", "protein_name": "Klotho", "gene_name": "KL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1012 }, "evidence": [ { "id": "E1BAI2", "url": "https://omabrowser.org/oma/group/E1BAI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2Y9-1", "protein_name": "Klotho", "gene_name": "Kl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"uniprot_ac": "E1BAL1", "uniprot_id": "E1BAL1_BOVIN", "mass": { "chemical_mass": 32739.0, "monoisotopic_mass": 32739.0 }, "refseq": {}, "gene_names": [ { "name": "TPGS1", "type": "recommended", "evidence": [ { "id": "E1BAL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL1" } ] } ], "protein_names": [ { "name": "Tubulin polyglutamylase complex subunit 1", "type": "synonym", "evidence": [ { "id": "E1BAL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BAL1", "url": "https://www.uniprot.org/uniprotkb/E1BAL1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TPGS1", "url": "https://www.uniprot.org/uniprotkb/E1BAL1", "locus": { "chromosome": "7", "start_pos": 43169718, "end_pos": 43164789, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010772", "url": "https://www.ensembl.org/id/ENSBTAG00000010772" } ] } } ], "crossref": [ { "id": "E1BAL1", "url": "https://alphafold.ebi.ac.uk/entry/E1BAL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010772", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010772", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22960", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22960", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505683", "url": "https://www.ncbi.nlm.nih.gov/gene/505683", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505683", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505683", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FSDYIRQ", "url": "https://omabrowser.org/oma/group/FSDYIRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BAL1", "url": "https://www.orthodb.org/?gene=E1BAL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31932:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31932:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24480", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24480", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BAL1", "url": "https://www.uniprot.org/uniprotkb/E1BAL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BAL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALPVPLPSAKMAAVEKRRQAVAQATSFTDSGRPGVPRTAATAESEEDFLRQVGVTEMLRAALLKVLEARPEEPIAFLAHYFENMGLRSPANGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRTAFNNNVGVAYECLSASGRKKKPGLDGRTYSELLKRICRDGEAPEEVVAPLLRKIQCRDHEAVPLAVFRAGMLTCFVLLEFVARAGALYRLLEDPGLAMADRRLGQAVLDTLEGALQASDDTAPARYLEAGSRLGPDSLALAMDRALVARRPSAPMTREEFLEKAAALFIAKVKPVG", "length": 302, "header": "tr|E1BAL1-1|E1BAL1_BOVIN Isoform 1 of Tubulin polyglutamylase complex subunit 1 OS=Bos taurus OX=9913 GN=TPGS1 PE=4 SV=3 CANONICAL=E1BAL1-1" }, "isoforms": [ { "isoform_ac": "E1BAL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BAL1/entry#E1BAL1-1", "sequence": { "sequence": "MAALPVPLPSAKMAAVEKRRQAVAQATSFTDSGRPGVPRTAATAESEEDFLRQVGVTEMLRAALLKVLEARPEEPIAFLAHYFENMGLRSPANGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRTAFNNNVGVAYECLSASGRKKKPGLDGRTYSELLKRICRDGEAPEEVVAPLLRKIQCRDHEAVPLAVFRAGMLTCFVLLEFVARAGALYRLLEDPGLAMADRRLGQAVLDTLEGALQASDDTAPARYLEAGSRLGPDSLALAMDRALVARRPSAPMTREEFLEKAAALFIAKVKPVG", "length": 302, "header": "tr|E1BAL1-1|E1BAL1_BOVIN Isoform 1 of Tubulin polyglutamylase complex subunit 1 OS=Bos taurus OX=9913 GN=TPGS1 PE=4 SV=3 CANONICAL=E1BAL1-1" }, "locus": { "chromosome": "7", "start_pos": 43168714, "end_pos": 43164988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014258.8", "url": "https://www.ensembl.org/id/ENSBTAT00000014258.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014258.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014258.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505683", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505683", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1S0C9-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "TPGS1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATYEKRRAAVTPTAAAGSGLGDEAEFLLQADVTAMVREALLKVLEARPEEPVSFLADYFERLVLSSSGAAGEAAAELSGPMQRLSRALWYVRLAHHSHRTAFNNNISTAYEVLGAGGRRRRLGVDGRLYSELLRRICQHGDAPQEVAAELLRRVQCRDHEAVPFDVFRYGVLTCFVLLEFVTKARMLYDVLDSGAGVADKSVCQAVLCTLEEALGASGLSVPVRYLEAGSRLGPDCLALAMDRALQERKLSTTMSREEFLKKATALFVAKVKPVE", "length": 276 }, "evidence": [ { "id": "E1BAL1", "url": "https://omabrowser.org/oma/group/E1BAL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8C2MJH8-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "Tpgs1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAALPVPLPSAKMAAVEKRRLAVTPAASFADSGRTTVSQAAAAAESEEDFLRQVGVTEMLRAALLKVLETRPEEPIAFLAHYFENMGLRSPANGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRTAFNNNVSVAYECLSASGRKKKPGLDGRTYSELLKRVCRDGGAPEEVVAPLLRKIQCRDHEAVPLGIFRAGMLSCFVLLEFVARASALFQLLEDPGLAVADRRVGQAVLDTLEGALGAGDLAAAPTHYLEAGSRLGPDSLARALDRAATGRRPSAPMAREEFLEKAAALFIAKVKPVG", "length": 303 }, "evidence": [ { "id": "E1BAL1", "url": "https://omabrowser.org/oma/group/E1BAL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B0S661-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "tpgs1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEKRRAGVLVSGSSSSSGCEADQEFVSRSGVSALLAGALLRLLDCRSGDPLGFLAEHFAHLSAEAEEGGAEQRSLSRALWMLSLQHHSQRSAFNSSVRVSYDLLSQCGAGVGGVGGRLYTETLQSLCSEGGLSASTSAPLLRRLQCREHETVPFELYRQAVLTCSVFADYIRKSQCLYAAVASAPDRPAQRTLCCAVLETLKEALETADGPDTARYLEASAKISPAKVAQAMAEAHSQTRDGETMDAQEFEDAAAALFIARVRTVT", "length": 267 }, "evidence": [ { "id": "E1BAL1", "url": "https://omabrowser.org/oma/group/E1BAL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A463-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "Tpgs1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALPVPLPPAKMAAVEKRRPAVAPAANFPDSGRTSVSQAVAAAESEEDFLRQVGVTEMLRAALLKVLETRPEEPIAFLAHYFENMGLRSPANGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRTAFNNNVSVAYECLSASGRKKKPGLDGRTYSELLKRVCRDGGAPEEVVAPLLRKIQCRDHEAVPLGIFRTGMLSCFVLLEFVARASALFQLLEDPGLAVADRRVGQAVLDTLEGALSAGDLATAPTHYLEAGSRLGPDNLARALDRAAAGRRPSAPMAREEFLEKAAALFIAKVKPVG", "length": 303 }, "evidence": [ { "id": "E1BAL1", "url": "https://omabrowser.org/oma/group/E1BAL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZTW0-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "TPGS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVEKRRQAVPPPAGFTDSGRQSVSRAAGAAESEEDFLRQVGVTEMLRAALLKVLEARPEEPIAFLAHYFENMGLRSPVNGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRAAFNNNVSVAYECLSAGGRRKRPGLDGRTYSELLRRICRDGQAPEEVVAPLLRKVQCRDHEAVPLSVFRAGTLTCFVLLEFVARAGALFQLLEDSAAAVADRRVGQAVLDTLEGALQASDAAAPARFLEAGSRLGPDSLALALDRAVGGRRPSAPMTREEFLERAAALFIAKVKPVG", "length": 290 }, "evidence": [ { "id": "E1BAL1", "url": "https://omabrowser.org/oma/group/E1BAL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99MS8-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "Tpgs1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALPVPLPPTKMAAVEKRRPAVAPAANFPDSGRTSVSQAAAAAESEEDFLRQLGVTEMLRAALLKVLEIRPEEPIAFLAHYFENMGLRSPTNGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRTAFNNNVSVAYECLSASGRKKKPGLDGRTYSELLKRVCRDGGAPEEVVAPLLRKIQCRDHEAVPLGIFRTGMLSCFVLLEFVARAGALFQLLEDPGQAVADRRVGQAVLDTLEGALSAGDMATAPTHYLEAGSRLGPDNLARALDRAASGRRPSVPMAREEFLEKAAALFIAKVKPVG", "length": 303 }, "evidence": [ { "id": "E1BAL1", "url": "https://omabrowser.org/oma/group/E1BAL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "tubulin-glutamic acid ligase activity", "id": "GO:0070740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070740", "evidence": [ { "database": "UniProtKB", "id": "E1BAL1", "url": "https://www.uniprot.org/uniprotkb/E1BAL1" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BAL1", "url": "https://www.uniprot.org/uniprotkb/E1BAL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BAL1", "url": "https://www.uniprot.org/uniprotkb/E1BAL1" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "E1BAL1", "url": "https://www.uniprot.org/uniprotkb/E1BAL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "E1BAL1", "url": "https://www.uniprot.org/uniprotkb/E1BAL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BAL1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 302, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BAL1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BAL1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BAL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL1" }, { "id": "PF24480", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24480" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubulin polyglutamylase complex subunit 1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 106, "end_pos": 299, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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GN=LYL1 PE=4 SV=3 CANONICAL=E1BAR3-1" }, "locus": { "chromosome": "7", "start_pos": 12477707, "end_pos": 12475703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025739.6", "url": "https://www.ensembl.org/id/ENSBTAT00000025739.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025739.4", "url": "https://www.ensembl.org/id/ENSBTAP00000025739.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 13, "start_aa": "Thr", "end_pos": 13, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr13", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BAR7-1", "uniprot_ac": "E1BAR7", "uniprot_id": "E1BAR7_BOVIN", "mass": { "chemical_mass": 70503.0, "monoisotopic_mass": 70503.0 }, "refseq": { "ac": "NP_001179260", "name": "XK-related protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179260" }, "gene_names": [ { "name": "XKR6", "type": "recommended", "evidence": [ { "id": "E1BAR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAR7" } ] }, { "name": "XKR6", "type": "synonym", "evidence": [ { "id": "NP_001179260", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179260" } ] } ], "protein_names": [ { "name": "XK-related protein", "type": "recommended", "evidence": [ { "id": "E1BAR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAR7/entry#names_and_taxonomy" } ] }, { "name": "XK-related protein 6", "type": "synonym", "evidence": [ { 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"id": "PTHR16024:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179260", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179260", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BAR7", "url": "https://www.uniprot.org/uniprotkb/E1BAR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BAR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAKSDGGGVGVGFAQLHNLDEAVGSGGEEDGEPGGGGCGGGGDGSEPGESSSLHICHCCNTSSCYWGCRSACLRSLLGKKPRRSAAAADGGDQPLQPPAAAGRQPPTPSAERLQPPQVERPWLDCLWIVLALLVFFGDVGTDLWLALDYYRKGDYGYFGLTLFFVLVPSLLVQSLSFRWFVQDYTGGGLGAVEGLSSRGPPMMGAGYGHGAGPAATPGAQRLCRLSVWIWQSVIHLLQMGQVWRYIRTMYLGIQSQRQKEHQRRFYWAMMYEYADVNMLRLLETFLESAPQLVLQLCIMIQKSRAETLPCVSSVTSLMSLAWVLASYHKLLRDSRDDKKSMSYRGALIHLFWRLFTISSRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNMVVGIVYIFCWFNVKEGRTRYRMFAYYTIVLTENAALTFLWYFYRNPETTDSYAVPALCCVFISFVAGIALMLLYYGVLHPTGPRVKILASSCCAELLWGIPLPPDVEPMAPQTPGYRGTQVTPTRAVTEQQEDLTADTCLPVFQVRPMGPSTPTGRPYLPEGPLIKIDMPRKRYPAWDAHFVDRRLRRTINILQYVTPTAVGIRYRDGPLLYELLQYESSL", "length": 631, "header": "tr|E1BAR7-1|E1BAR7_BOVIN Isoform 1 of XK-related protein OS=Bos taurus OX=9913 GN=XKR6 PE=3 SV=3 CANONICAL=E1BAR7-1" }, "isoforms": [ { "isoform_ac": "E1BAR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BAR7/entry#E1BAR7-1", "sequence": { "sequence": "MAAKSDGGGVGVGFAQLHNLDEAVGSGGEEDGEPGGGGCGGGGDGSEPGESSSLHICHCCNTSSCYWGCRSACLRSLLGKKPRRSAAAADGGDQPLQPPAAAGRQPPTPSAERLQPPQVERPWLDCLWIVLALLVFFGDVGTDLWLALDYYRKGDYGYFGLTLFFVLVPSLLVQSLSFRWFVQDYTGGGLGAVEGLSSRGPPMMGAGYGHGAGPAATPGAQRLCRLSVWIWQSVIHLLQMGQVWRYIRTMYLGIQSQRQKEHQRRFYWAMMYEYADVNMLRLLETFLESAPQLVLQLCIMIQKSRAETLPCVSSVTSLMSLAWVLASYHKLLRDSRDDKKSMSYRGALIHLFWRLFTISSRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNMVVGIVYIFCWFNVKEGRTRYRMFAYYTIVLTENAALTFLWYFYRNPETTDSYAVPALCCVFISFVAGIALMLLYYGVLHPTGPRVKILASSCCAELLWGIPLPPDVEPMAPQTPGYRGTQVTPTRAVTEQQEDLTADTCLPVFQVRPMGPSTPTGRPYLPEGPLIKIDMPRKRYPAWDAHFVDRRLRRTINILQYVTPTAVGIRYRDGPLLYELLQYESSL", "length": 631, "header": "tr|E1BAR7-1|E1BAR7_BOVIN Isoform 1 of XK-related protein OS=Bos taurus OX=9913 GN=XKR6 PE=3 SV=3 CANONICAL=E1BAR7-1" }, "locus": { "chromosome": "8", "start_pos": 8413435, "end_pos": 8148028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007096.7", "url": "https://www.ensembl.org/id/ENSBTAT00000007096.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007096.6", "url": "https://www.ensembl.org/id/ENSBTAP00000007096.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 108, "start_aa": "Thr", "end_pos": 108, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr108", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 217, "start_aa": "Thr", "end_pos": 217, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr217", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539914", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539914", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BAR7", "url": "https://www.uniprot.org/uniprotkb/E1BAR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "engulfment of apoptotic cell", "id": "GO:0043652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043652", "evidence": [ { "database": "UniProtKB", "id": "E1BAR7", "url": "https://www.uniprot.org/uniprotkb/E1BAR7" } ], "pmid": "" }, { "name": "phosphatidylserine exposure on apoptotic cell surface", "id": "GO:0070782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070782", "evidence": [ { "database": "UniProtKB", "id": "E1BAR7", "url": "https://www.uniprot.org/uniprotkb/E1BAR7" } ], "pmid": "" }, { "name": "apoptotic process involved in development", "id": "GO:1902742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902742", "evidence": [ { "database": "UniProtKB", "id": "E1BAR7", "url": "https://www.uniprot.org/uniprotkb/E1BAR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BAR7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 631, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BAR7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BAR7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 108, 217 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BAR8-1", "uniprot_ac": "E1BAR8", "uniprot_id": "E1BAR8_BOVIN", "mass": { "chemical_mass": 52749.0, "monoisotopic_mass": 52749.0 }, "refseq": { "ac": "NP_001179569", "name": "doublesex- and mab-3-related transcription factor A1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179569" }, "gene_names": [ { "name": "DMRTA1", "type": "recommended", "evidence": [ { "id": "E1BAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAR8" } ] }, { "name": "DMRTA1", "type": "synonym", "evidence": [ { "id": "NP_001179569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179569" } ] } ], "protein_names": [ { "name": "DMRT like family A1", "type": "synonym", "evidence": [ { "id": "E1BAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAR8/entry#names_and_taxonomy" } ] }, { "name": "doublesex- and mab-3-related transcription factor A1", "type": "synonym", "evidence": [ { "id": "NP_001179569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179569" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BAR8", "url": "https://www.uniprot.org/uniprotkb/E1BAR8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DMRTA1", "url": "https://www.uniprot.org/uniprotkb/E1BAR8", "locus": { "chromosome": "8", "start_pos": 21729254, "end_pos": 21735209, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001315", "url": "https://www.ensembl.org/id/ENSBTAG00000001315" } ] } } ], "crossref": [ { "id": "E1BAR8", "url": "https://alphafold.ebi.ac.uk/entry/E1BAR8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001315", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001315", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14417", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14417", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "527219", "url": "https://www.ncbi.nlm.nih.gov/gene/527219", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:527219", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527219", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RELQFMY", "url": "https://omabrowser.org/oma/group/RELQFMY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BAR8", "url": "https://www.orthodb.org/?gene=E1BAR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12322:SF71", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12322:SF71", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00751", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00751", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20624", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20624", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179569", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BAR8", "url": "https://www.uniprot.org/uniprotkb/E1BAR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAR8-1", "url": "https://www.uniprot.org/uniprotkb/E1BAR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQSQCGSRDRSRSGPLHLAPGLVVAAPPPPSPALPVPPGIPVPPTFLRPSSLFLRAASSAGSGGCPPPAELERGVGAVAGGYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLQRLLYPGPSGPGGRSSGGSSRTETSQTTSSGPATVTALGLSASRQASGLATPVFEIFQPDYIEEKQGQKESKCDSCQSGQEELGSKSHQFTLRSSPKSNDVTGKQNIRSSISENPNKDDSIQSLHPGEQSGGEESPRSLSSSDLESGNESEWAKDFTDSTASHPTVSSRPRDPLDILTKIFPSYRRSRLEGILQFCKGDVVQAIEEILNGKEHKPDTRDLANSGALENTAFPRVSNFSLAGIGFGTLGNKSAFSPLHTSSASYGGDSSLYSLNPRLGISPFRLAYSSPGRGLSGFMSPYLTPGLVPSLPCRPALDYAFSGMIRDSSYLPIKDSVTGGRLYSRPNQSNL", "length": 496, "header": "tr|E1BAR8-1|E1BAR8_BOVIN Isoform 1 of DMRT like family A1 OS=Bos taurus OX=9913 GN=DMRTA1 PE=3 SV=1 CANONICAL=E1BAR8-1" }, "isoforms": [ { "isoform_ac": "E1BAR8-1", "url": "https://www.uniprot.org/uniprotkb/E1BAR8/entry#E1BAR8-1", "sequence": { "sequence": "MEQSQCGSRDRSRSGPLHLAPGLVVAAPPPPSPALPVPPGIPVPPTFLRPSSLFLRAASSAGSGGCPPPAELERGVGAVAGGYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLQRLLYPGPSGPGGRSSGGSSRTETSQTTSSGPATVTALGLSASRQASGLATPVFEIFQPDYIEEKQGQKESKCDSCQSGQEELGSKSHQFTLRSSPKSNDVTGKQNIRSSISENPNKDDSIQSLHPGEQSGGEESPRSLSSSDLESGNESEWAKDFTDSTASHPTVSSRPRDPLDILTKIFPSYRRSRLEGILQFCKGDVVQAIEEILNGKEHKPDTRDLANSGALENTAFPRVSNFSLAGIGFGTLGNKSAFSPLHTSSASYGGDSSLYSLNPRLGISPFRLAYSSPGRGLSGFMSPYLTPGLVPSLPCRPALDYAFSGMIRDSSYLPIKDSVTGGRLYSRPNQSNL", "length": 496, "header": "tr|E1BAR8-1|E1BAR8_BOVIN Isoform 1 of DMRT like family A1 OS=Bos taurus OX=9913 GN=DMRTA1 PE=3 SV=1 CANONICAL=E1BAR8-1" }, "locus": { "chromosome": "8", "start_pos": 21734930, "end_pos": 21730258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001735.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001735.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001736.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001736.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:527219", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527219", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZIZ0-1", "protein_name": "DMRT-like family A1", "gene_name": "Dmrta1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQFPRRDRSGGCRPHLGPGRAVAPASAARSVSSGIPVSATFLRPPGLFLRSTASAGRAGCVPGPGLDRALGAVGCGYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLHRLLYQGPSGPGAPASGGSGRTESPQVLSSPMTVAALGAGASRHPGSRSVPAFEVFQQDFAERKQEPKQSNCESCQSRHEEPVSNTHHRSPGSSNGNVTMEKQGFMSSISEQSDKSTIILSPCPTDQSGGEDSPRSFSSSDLESGNESEWARDYTATTASLSTVTSRPRDPLGILTRIFPGYKRSRLEGILQFCKGDVVQAIEQILNGKEHKPDCRDLAHADLENAAFQRASDFSLAGIGFGTLNNKSALSPLEAASAAYGGDSSLYSFNPRLAFSPLRLAYSSPGRALSGFMSPYLTPGLVPALPFRPTLDYAFPGMIREPPHLPSKHLVTGGRLYFRPNQEHL", "length": 488 }, "evidence": [ { "id": "E1BAR8", "url": "https://omabrowser.org/oma/group/E1BAR8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SNK8-1", "protein_name": "DMRT like family A1", "gene_name": "DMRTA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQSQCGSRDLSSSGRPSLAPGLVAAAPHPQSPMLPVPPGIPLPPTFLRPPSLFLRAATAATSGSGGCPQAAGLERGVGAVACSYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEAQGLQRLLYSGPSGPGGQTSGGSRRTENLQTASSSAVVTALGLSALRQASGLATPACKIFQQDYTEGKQGQKENKCDSCQSKQEEPVCKSHHSTLGSSPKSNDVIGKQNIRSSVSENLNKDDSIQSPHPGEQSGGEESPRSPSSSDLESGNESEWAKDFTAARASLPPMSSRPRDPLDILIKIFPSYRCSRLESILQFCKGDVVQAIEQVLNGKEHQTDTRDLANSGELENTAFPRASNFSLAGIGFGTLGNKSAFSPLHTTSASYGGDSSLYSLNPRLGISPLRLAYSSPGRGLSSFMSPYLTPGLVPTLPFRPALDYAFPGMIRDSSYLPSKDSVTSDRLYSRLNQDNL", "length": 497 }, "evidence": [ { "id": "E1BAR8", "url": "https://omabrowser.org/oma/group/E1BAR8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5VZB9-1", 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"organism": "Mus musculus", "sequence": { "sequence": "MERLPHGRRDRSGGCRPHLAPGRAAAPASAARSVSSGIPVSATFLRPPGLFLRSTASSGRAGCAPGPGLDRALGAVGCGYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLHRLLYQGSSGSGAQASGGSGRTESPQVLNNPMAVAVLGAGASRHPGSRSVPTFEVFQQDYADRKQEPKQRNCESCQSRQEEPVSNTHHHSLGSSKGNVTVEKQGFMSSIPEHPDKSTIILSPCPTDQSGGEDSPRSFSSSDLESGNESEWARDYIATRASLSTVTSRPRDPLGILTRIFPGYKHSRLEGILQFCKGDVVQAIEQILNGREHKPDCRDLARADLENAAFQRASDFSLAGIGFGTLSNKSALSPLEAASAAYGGDSTLYSFNPRLAFSPLRLAYSSPGRALSGFVSPYLTPGLVPALPFRPTLDYAFPGMIREPSHLPSKHLVAGGRLYFRPNQEHL", "length": 490 }, "evidence": [ { "id": "E1BAR8", "url": "https://omabrowser.org/oma/group/E1BAR8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BAR8", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BAR8", "url": "https://www.uniprot.org/uniprotkb/E1BAR8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BAR8", "url": "https://www.uniprot.org/uniprotkb/E1BAR8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BAR8", "url": "https://www.uniprot.org/uniprotkb/E1BAR8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BAR8", "url": "https://www.uniprot.org/uniprotkb/E1BAR8" } ], "pmid": "" } ] } ] }, 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[ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BAT2", "url": "https://www.uniprot.org/uniprotkb/E1BAT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAT2-1", "url": "https://www.uniprot.org/uniprotkb/E1BAT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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[], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BAT2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 321, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BAT2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BAT2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BAT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAT2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 296, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BAT3-1", "uniprot_ac": "E1BAT3", "uniprot_id": "E1BAT3_BOVIN", "mass": { "chemical_mass": 123168.0, "monoisotopic_mass": 123168.0 }, "refseq": { "ac": "NP_001179192", "name": "leukemia inhibitory factor receptor precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179192" }, "gene_names": [ { "name": "LIFR", "type": "recommended", "evidence": [ { "id": "E1BAT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ] }, { "name": "LIFR", "type": "synonym", "evidence": [ { "id": "NP_001179192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179192" } ] } ], "protein_names": [ { "name": "Leukemia inhibitory factor receptor", "type": "recommended", "evidence": [ { "id": "E1BAT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAT3/entry#names_and_taxonomy" } ] }, { "name": "LIF receptor alpha", "type": "synonym", "evidence": [ { "id": "NP_001179192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179192" } ] }, { "name": "leukemia inhibitory factor receptor alpha", "type": "synonym", "evidence": [ { "id": "NP_001179192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179192" } ] }, { "name": "leukemia inhibitory factor receptor precursor", "type": "synonym", "evidence": [ { "id": "NP_001179192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179192" } ] } ], "function": [ { "annotation": "Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3#function" }, { "database": "UniProtKB", "id": "ARBA00054569", "url": "https://www.uniprot.org/uniprotkb/ARBA00054569#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LIFR", "url": "https://www.uniprot.org/uniprotkb/E1BAT3", "locus": { "chromosome": "20", "start_pos": 35950860, "end_pos": 35900700, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010423", "url": "https://www.ensembl.org/id/ENSBTAG00000010423" } ] } } ], "crossref": [ { "id": "E1BAT3", "url": "https://alphafold.ebi.ac.uk/entry/E1BAT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010423", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010423", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539504", "url": "https://www.ncbi.nlm.nih.gov/gene/539504", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539504", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539504", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FFLYGCK", "url": "https://omabrowser.org/oma/group/FFLYGCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BAT3", "url": "https://www.orthodb.org/?gene=E1BAT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23036:SF105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23036:SF105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17971", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17971", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25552", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25552", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6788467", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6788467", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179192", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179192", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAT3-1", "url": "https://www.uniprot.org/uniprotkb/E1BAT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMDISLCVKRPSWLVDRKRMRMASNSQWLLLTAVLLYLTNQVNSQKKSTPHDLKCVTNNLKVWDCSWRALFGAGRAASYEVCIEKRSRTCYLLEKNTTIPPLLPGHYEITVHPLYEFGSSKSKFILNEKNISLIPETPEILNLSADFSTSTLHLKWNDKGSVFPHYSNVIWEIKVLHKKNMEIVKLVTYSTTLNGRDTIHHWNWTSDMPLECAIHYVGIRCYIDDPQFSGHKEWSDWSLLKNISLPPDSQTKVFPQDKVILAGSDITVCCVTQEKVLSAQIGSTHCPLIHLDGENVAIRIRNISASASSGTNVVFSVEDNIFGTVVFAGYPPDIPQKLNCETYDLKEIICTWNPGRPTSLEGPRSTSYTLFESFSGKYVRFKGDEVSANENYQLFLQILSSQEIHNFTLNAQNLLGQTESTLLVNITEKVHPRIPTSLKAKDINSTAVILSWHLPGNFTKVKLLCQIEINKTNSEHELRNVTMRGVESSNYLTTVDKLNPYTIYTFRIRCSTDPFWKWSKWSNEKQCLTTEAIPSKGPDIWREWSSDGRNLIIYWKPLPINEAYGKILSYNVSYSSDEETKSLSEIPDTQHRAELQLDKNDYIISVVAKNSAGSSPPSKIASMEIPNDDLKIEQALGMGNRILLTWNYDPNMTCDYVIKWCNSSQSGPCLMDWKKVPPNSTETVIESDQFRPGVRYNFSVYGCRNQGYQLLRSVIGYVEELAPAVAPNFTVEDTSADSILVKWEEIPVEELRGFLRGYLFYFEKGERDTSKIMGLEPGRFDTKVKNITDISQKTLRIADLQGKTSYHLVLRAYTGGGMGPERSMFVVTKENSEGLIIAILIPVAVAVIIGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGNSALKTLEMNPCTPNNVEVLETRSVALKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPVIEEELANPGAEGGGASQVIYIDVQSMYQPQAKPEGELDSDPVGGAGYKPQMHLPVTSTVDDLDADDDLDKTAGYRPQANVNTWNLVSPDSPRSTDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKSSGGGWSFTNFFQNKPND", "length": 1095, "header": "tr|E1BAT3-1|E1BAT3_BOVIN Isoform 1 of Leukemia inhibitory factor receptor OS=Bos taurus OX=9913 GN=LIFR PE=3 SV=2 CANONICAL=E1BAT3-1" }, "isoforms": [ { "isoform_ac": "E1BAT3-1", "url": "https://www.uniprot.org/uniprotkb/E1BAT3/entry#E1BAT3-1", "sequence": { "sequence": "MMDISLCVKRPSWLVDRKRMRMASNSQWLLLTAVLLYLTNQVNSQKKSTPHDLKCVTNNLKVWDCSWRALFGAGRAASYEVCIEKRSRTCYLLEKNTTIPPLLPGHYEITVHPLYEFGSSKSKFILNEKNISLIPETPEILNLSADFSTSTLHLKWNDKGSVFPHYSNVIWEIKVLHKKNMEIVKLVTYSTTLNGRDTIHHWNWTSDMPLECAIHYVGIRCYIDDPQFSGHKEWSDWSLLKNISLPPDSQTKVFPQDKVILAGSDITVCCVTQEKVLSAQIGSTHCPLIHLDGENVAIRIRNISASASSGTNVVFSVEDNIFGTVVFAGYPPDIPQKLNCETYDLKEIICTWNPGRPTSLEGPRSTSYTLFESFSGKYVRFKGDEVSANENYQLFLQILSSQEIHNFTLNAQNLLGQTESTLLVNITEKVHPRIPTSLKAKDINSTAVILSWHLPGNFTKVKLLCQIEINKTNSEHELRNVTMRGVESSNYLTTVDKLNPYTIYTFRIRCSTDPFWKWSKWSNEKQCLTTEAIPSKGPDIWREWSSDGRNLIIYWKPLPINEAYGKILSYNVSYSSDEETKSLSEIPDTQHRAELQLDKNDYIISVVAKNSAGSSPPSKIASMEIPNDDLKIEQALGMGNRILLTWNYDPNMTCDYVIKWCNSSQSGPCLMDWKKVPPNSTETVIESDQFRPGVRYNFSVYGCRNQGYQLLRSVIGYVEELAPAVAPNFTVEDTSADSILVKWEEIPVEELRGFLRGYLFYFEKGERDTSKIMGLEPGRFDTKVKNITDISQKTLRIADLQGKTSYHLVLRAYTGGGMGPERSMFVVTKENSEGLIIAILIPVAVAVIIGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGNSALKTLEMNPCTPNNVEVLETRSVALKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPVIEEELANPGAEGGGASQVIYIDVQSMYQPQAKPEGELDSDPVGGAGYKPQMHLPVTSTVDDLDADDDLDKTAGYRPQANVNTWNLVSPDSPRSTDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKSSGGGWSFTNFFQNKPND", "length": 1095, "header": "tr|E1BAT3-1|E1BAT3_BOVIN Isoform 1 of Leukemia inhibitory factor receptor OS=Bos taurus OX=9913 GN=LIFR PE=3 SV=2 CANONICAL=E1BAT3-1" }, "locus": { "chromosome": "20", "start_pos": 35949856, "end_pos": 35900713, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013754.8", "url": "https://www.ensembl.org/id/ENSBTAT00000013754.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013754.6", "url": "https://www.ensembl.org/id/ENSBTAP00000013754.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539504", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539504", "resource": "KEGG Pathway" }, { "id": "R-BTA-6788467", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6788467", "resource": "Reactome", "description": "IL-6-type cytokine receptor ligand interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QCV3-1", "protein_name": "Leukemia inhibitory factor receptor", "gene_name": "Lifr", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDVYSGWKQPSWMVDSKRMRMTLNLPWLLSALTLLHLTIQAHSLKRGAAQDLKCTTKNMHVWDCTWSASAGVSPGTVKEVCIKDRLNSCHRLESTNIKIAALSPGDHEVTINYLNGFQNKFTLNEKDVSLIPDTPESLNLSADFSTSTLHLRWNDRGSAFPYPSNATWEIKVLQNPSMEPVKLVSFNTTLSGQDIVHHWNWTSDLPLQCAPHSVGIRWYIDHHRFSGYKVWSDWSLLKNISWTPNSETNVFPQDKVILAGSDITFCCVSQTKVLSGQIGRTFCPLIHLYGENVAIRIQNISVSENSGTNVVFTTEDNVYGTVVFAGYPPDVPQKLNCETHDFKEIICSWNPGRPTGLVGPRNTDYTLSESISGKSVAFKRFETLTNESYRLAFQMLPGQEIHNFTLTGRNPLGHAESAIFINITERVVPHVPVSLRVKDINSTVVALSWHLPGNFAKINLLCQVQICKASSEQEVRNATIKGAEGSSYLVAVDKLNPYTLYTFRVRCSTETFWKWSKWSNEKRHLTMEAIPSRGPDTWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSNEETQSLSEILDPQHKAEIQLEKNDYIISVVAKNSAGSSPPSKIASMEIPNDDILVEQAVGMGKRIFLSWHPDPNMTCDYVIKWCNSSRSEPCLMDWIKVPSNSTETIIESDQFQPGVRYNFYLYGCTNQGYQLLRSIIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFQKGERDTPKTRTFETGHSDIKLKNITDISQKTLRIADLQGKTSYHLVLRAYTHGGLGPEKSMFVVTKENSVGLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSICEGSSALKTLEMNPCTPNNVEVLESRSIVPKIEDTEIISPVAERPGECSEADPENHVVVSYCPPIIEEEISNPAADEAGGTSQVVYIDVQSMYQPQAKPEEEQGIDPGVVAGYKPQMRLPINSAVEDTTAEDEADKTAGYRPQANVNTWNLVSPDSPRSTDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKSNGGGWSFTNFFQNKPND", "length": 1093 }, "evidence": [ { "id": "E1BAT3", "url": "https://omabrowser.org/oma/group/E1BAT3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1NN90-1", "protein_name": "Leptin receptor", "gene_name": "LIFR", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MWTNPNLRCLLALAFLCLTSLVHSREIGSQGDPQNLKCVTHNLHKMVCTWEISSERRHGQTEFCYATECFKTKEERVEIPVPESSTTVKITTYSISGTAFATRHFEIHKKDISFVPLAPRILSLTPDFSTFTLTLKWSDNGSAFPYGLDASWEIEVLRNGNNVTRETYNSKLIHEDIIHSWNWKSDMPLECTSHHVRIRHYINITQFDGPKDWSAWSRVVVPGKDTEPSGSGLFPQDTVVAVGSNVTFCCVHKEGQQIQRMSYGAKDYPLIRLSSRSSAIRVLNANASSASGTNIVCTMSEDWMDGAVLFVGYGPDTPKGLSCETSNFVIIKCTWKPGRATGLYKARGTKYSLTESISGKNVSCEVNEMKKKHVCGFPVLADQKTYSFILGASNPIGQTEASLLVDLNQRVNPETPEKLTASGNSSTSVHLRWFINGSFAEIRLLCEIEISSGHSEQKLHNVSMPGGKFSNYTAQLNALHPYTKYQFRVRCSAADHFWRWSDWSGTLEYTTLEAPPTRGPDIWRERSPSGKSLRIFWKPLSLSEANGKIVSYEVSCYLLEKSLEYKEVMEPSNSTEIKLGRNDCVISVVAKNHAGSSPPSRITSVELPSDNVKTDRAVAMGNGIYISWNSFPNMTCGYIVKWCHSSGSEPCSVDWQKFPSNTTDAVIKSALFRPGVRYNFSLYGCKSSGYQLLKNITGYMKELPPKRAPNFTVEETSSDSILVKWEDMSIEDCQGFLEGYRLSFAKGEKDALRPRLLESGNPELKVKNITDLTKKSLKILDLQGKTSYQLDLQAYTAGGLSPPNSLYVVTKEDSVGLIIAILFPVAVVFLLGVVTSIFCYRKREWIKETFYPEIPNPENSKALQFQKNICEGNKSLKTLEMNPCTPNTVEVVETQSAAPKIEDTEMMSTTTDTIVPEDGSDSETENHVVVSYCPPIIEEEISNPTMDEPVGLSQVVYIDIQSMYQPQIKPEEESEIDLVTTAGYKPQMQLPVSALKIESRTPAEEESDKTAGYRPQANTNAWNMDTPDSPGSVESNNENTSFGSPCSINSRQFLLPPKDDEDSPKPSNTGWSFTHFFQNKPND", "length": 1083 }, "evidence": [ { "id": "E1BAT3", "url": "https://omabrowser.org/oma/group/E1BAT3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O70535-1", "protein_name": "Leukemia inhibitory factor receptor", "gene_name": "Lifr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"length": 1093 }, "evidence": [ { "id": "E1BAT3", "url": "https://omabrowser.org/oma/group/E1BAT3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P42702-1", "protein_name": "Leukemia inhibitory factor receptor", "gene_name": "LIFR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1097 }, "evidence": [ { "id": "E1BAT3", "url": "https://omabrowser.org/oma/group/E1BAT3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P42703-1", "protein_name": "Leukemia inhibitory factor receptor", "gene_name": "Lifr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAYSWWRQPSWMVDNKRSRMTPNLPWLLSALTLLHLTMHANGLKRGVQDLKCTTNNMRVWDCTWPAPLGVSPGTVKDICIKDRFHSCHPLETTNVKIPALSPGDHEVTINYLNGFQSKFTLNEKDVSLIPETPEILDLSADFFTSSLLLKWNDRGSALPHPSNATWEIKVLQNPRTEPVALVLLNTMLSGKDTVQHWNWTSDLPLQCATHSVSIRWHIDSPHFSGYKEWSDWSPLKNISWIRNTETNVFPQDKVVLAGSNMTICCMSPTKVLSGQIGNTLRPLIHLYGQTVAIHILNIPVSENSGTNIIFITDDDVYGTVVFAGYPPDVPQKLSCETHDLKEIICSWNPGRITGLVGPRNTEYTLFESISGKSAVFHRIEGLTNETYRLGVQMHPGQEIHNFTLTGRNPLGQAQSAVVINVTERVAPHDPTSLKVKDINSTVVTFSWYLPGNFTKINLLCQIEICKANSKKEVRNATIRGAEDSTYHVAVDKLNPYTAYTFRVRCSSKTFWKWSRWSDEKRHLTTEATPSKGPDTWREWSSDGKNLIVYWKPLPINEANGKILSYNVSCSLNEETQSVLEIFDPQHRAEIQLSKNDYIISVVARNSAGSSPPSKIASMEIPNDDITVEQAVGLGNRIFLTWRHDPNMTCDYVIKWCNSSRSEPCLLDWRKVPSNSTETVIESDQFQPGVRYNFYLYGCTNQGYQLLRSIIGYVEELAPIVAPNFTVEDTSADSILVKWDDIPVEELRGFLRGYLFYFQKGERDTPKTRSLEPHHSDIKLKNITDISQKTLRIADLQGKTSYHLVLRAYTHGGLGPEKSMFVVTKENSVGLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSNALKTLEMNPCTPNNVEVLESRSIVPKIEDTEIISPVAERPGERSEVDPENHVVVSYCPPIIEEEITNPAADEVGGASQVVYIDVQSMYQPQAKAEEEQDVDPVVVAGYKPQMRLPISPAVEDTAAEDEEGKTAGYRPQANVNTWNLVSPDSPRSTDSNNEVVSFGSPCSINSRQFLIPPKDEDSPKSNGGGWSFTNFFQNKPND", "length": 1092 }, "evidence": [ { "id": "E1BAT3", "url": "https://omabrowser.org/oma/group/E1BAT3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "ciliary neurotrophic factor receptor complex", "id": "GO:0070110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070110", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "leukemia inhibitory factor receptor activity", "id": "GO:0004923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004923", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ], "pmid": "" }, { "name": "coreceptor activity", "id": "GO:0015026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ], "pmid": "" }, { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ], "pmid": "" }, { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ], "pmid": "" }, { "name": "oncostatin-M receptor activity", "id": "GO:0004924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004924", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" } ], "pmid": "" }, { "name": "ciliary neurotrophic factor receptor binding", "id": "GO:0005127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005127", "evidence": [ { "database": "UniProtKB", "id": "E1BAT3", "url": 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"annotation": "n_glycosylation_sequon" }, { "start_pos": 786, "end_pos": 788, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BAT3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1095, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BAT3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BAT3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BAT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAT3" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": 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0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BAU5-1", "uniprot_ac": "E1BAU5", "uniprot_id": "E1BAU5_BOVIN", "mass": { "chemical_mass": 15376.0, "monoisotopic_mass": 15376.0 }, "refseq": { "ac": "XP_002692520", "name": "antileukoproteinase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692520" }, "gene_names": [ { "name": "LOC512548", "type": "recommended", "evidence": [ { "id": "E1BAU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAU5" } ] }, { "name": "LOC512548", "type": "synonym", "evidence": [ { "id": "XP_002692520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692520" } ] } ], "protein_names": [ { "name": "WAP domain-containing protein", "type": "recommended", "evidence": [ { "id": "E1BAU5", "database": 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"categories": [ "Protein" ] }, { "id": "E1BAW2", "url": "https://www.uniprot.org/uniprotkb/E1BAW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAW2-1", "url": "https://www.uniprot.org/uniprotkb/E1BAW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHQILLLLAVLTLGLATSQHRDKVPCRKVDKEVWCQGRGLLQVPSVLSRDIEVLNLSRNQLRSILALPLGFYTALRHLDLSANEISFLQPGVFQALPHLEHLNLAHNHLAVGTALNTGGLGPLLHLTSLDLSGNSLYSGLVEQLLGEAPALRTLSLAENSLTRLGRRTFLSTPALERLDLHSNVLMDIEDGAFEALPRLVHLNLSRNSLTCISDFSLQQLRVLDLSCNSIEAFQTAEPRAEYQLAWLDLRENKLLHFPDLSALPRLIYLNASNNLIRLPAEPPRGGAEGLHAPSEGWSSLPLSNPSRNTSTQPLSQLLNLDLSYNEIELVPEGFLEPLTSLRSLNLSRNCLRAFEAQPGSLPCLTLLDISHNALETLELGARALGSLRTLLLQDNALRDLPLYTFTSLASLQRLNLQGNRLSPCGGPAEPGPSGCVAFSGISSLRVLNLADNEMEILQAGAFLHTPLAELDLSSNPGLDVAPGALAGLEGSLEVLALQGNGLAVLQVDLPCFSCLKRLNLAENRLSRLPAWTQAVSLEVLDLRNNSFSLLPGSAMGGLENSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFGSQEEVSLSHVRPEDCEKGGLKNINLIIILTFAVVSAILLTTLATCCCVRRQKFSQQYKA", "length": 662, "header": "tr|E1BAW2-1|E1BAW2_BOVIN Isoform 1 of Transforming growth factor beta activator LRRC32 OS=Bos taurus OX=9913 GN=LRRC32 PE=3 SV=1 CANONICAL=E1BAW2-1" }, "isoforms": [ { "isoform_ac": "E1BAW2-1", "url": "https://www.uniprot.org/uniprotkb/E1BAW2/entry#E1BAW2-1", "sequence": { "sequence": "MSHQILLLLAVLTLGLATSQHRDKVPCRKVDKEVWCQGRGLLQVPSVLSRDIEVLNLSRNQLRSILALPLGFYTALRHLDLSANEISFLQPGVFQALPHLEHLNLAHNHLAVGTALNTGGLGPLLHLTSLDLSGNSLYSGLVEQLLGEAPALRTLSLAENSLTRLGRRTFLSTPALERLDLHSNVLMDIEDGAFEALPRLVHLNLSRNSLTCISDFSLQQLRVLDLSCNSIEAFQTAEPRAEYQLAWLDLRENKLLHFPDLSALPRLIYLNASNNLIRLPAEPPRGGAEGLHAPSEGWSSLPLSNPSRNTSTQPLSQLLNLDLSYNEIELVPEGFLEPLTSLRSLNLSRNCLRAFEAQPGSLPCLTLLDISHNALETLELGARALGSLRTLLLQDNALRDLPLYTFTSLASLQRLNLQGNRLSPCGGPAEPGPSGCVAFSGISSLRVLNLADNEMEILQAGAFLHTPLAELDLSSNPGLDVAPGALAGLEGSLEVLALQGNGLAVLQVDLPCFSCLKRLNLAENRLSRLPAWTQAVSLEVLDLRNNSFSLLPGSAMGGLENSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFGSQEEVSLSHVRPEDCEKGGLKNINLIIILTFAVVSAILLTTLATCCCVRRQKFSQQYKA", "length": 662, "header": "tr|E1BAW2-1|E1BAW2_BOVIN Isoform 1 of Transforming growth factor beta activator LRRC32 OS=Bos taurus OX=9913 GN=LRRC32 PE=3 SV=1 CANONICAL=E1BAW2-1" }, "locus": { "chromosome": "15", "start_pos": 56052796, "end_pos": 56045708, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001716.5", "url": "https://www.ensembl.org/id/ENSBTAT00000001716.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001716.3", "url": "https://www.ensembl.org/id/ENSBTAP00000001716.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:615467", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615467", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X8W1-1", "protein_name": "Leucine rich repeat containing 32", "gene_name": "LRRC32", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLYVIFLLSVVNGHQPAEGMPCEMANLQAFCHNKELRQIPRELHPNVNKIDLSGNLIQSIPDMPLPFYTSLQCLDLSSNQISFITPGVFAHMTSLLEINLANNNLYELAQTGTEGIGFLPKVEILDLSHNSLYNGMAEYFIKRAPALRYLSLAGNSIIMISHKMFQGSPNLVEIDLQSNIIMEIEEGAFETLLNLSRLNLSMNSITCISDFNLRQLEILDLSRNSIESFHTTESDDEYSLKCLDLSENKLLRFPVFPQVNKLVTLNLSKNLIQLTAESSRNKMNYMENEWLDAPFHLLDQKQSRNKSSLNLSHLAYLDLSYNEIKSIPDEFFESMFSLHTLNLSKNCLQTFEVTSDSTLVSLTVLDLSYNALQSLLLHADTLLNLKELYIQNNHLQVLQFDIFSRLTSLRWLNLQSNNITLCSMYSGLAKQRLAGEENGCISFVDAPALQHLSLADNMLSILPAHTFFKTSLIFLDLSMNPGLTVEVNALSGLEQSLEYLHLHGNSLIELNIDLPCFSHLRHLNLSENQLSWLPKWGSGSPLEVLDLRNNRFSTLQNSNILALENSLKNLYLTGNPLNCCGNMWLSLMIQNKNVQISNVEHLTCQYTQNFGYQEEMHIGNIRPEDCEKEDLKKINFLIILTVVLVLSVIIIGVGSFFCFRRQNFSQQFKA", "length": 671 }, "evidence": [ { "id": "E1BAW2", "url": "https://omabrowser.org/oma/group/E1BAW2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZVD5-1", "protein_name": "Transforming growth factor beta activator LRRC32", "gene_name": "Lrrc32", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYQILILLAMLTLGLAISQRRDQVPCRTVNKEALCHGLSLLQVPSVLSLDIQALYLSGNRLQSILVSPLSFYTALRHLDLSDNEISFLQPGVFQALPYLEHLNLAHNRLAAGMALNSGGLGRLPLVVSLDLSGNSLHGSLVERLLGEAPRLRTLSLAENSLTRLARHTFWGMPAMEQLDLHSNVLMDIEDGAFEALPQLTHLNLSRNSLTCISDFSLQQLQVLDLSCNSIETFQTAPESQAQFQLAWLDLRENKLLHFPDLAMFPRLIYLNVSNNLIQLPTGLPQDSEDLHAPSEGWSASLLSNPSRNASIHPLSQLLNLDLSYNEIELVPAGFLEHLTSLRFLNLSRNCLRSFEARRAGSLPCLVLLDLSHNVLEALELGTKVLGSLKTLLLQDNTLRELPPYTFAGLASLQRLNLQGNQVSPCGGQAEPGPPGCVDFSGIPTLHFLNMAGNSMETLRAGSFLHTPLTELDLSANPGLDVATGALVGLEASLEVLELQGNGLVVLRVDLPCFRRLKRLNLAENRLSHLPAWTRAVSLEVLDLRNNSFSLLPGNAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFGSQEEVSLSLVRPEDCEKGGLKNVNLIIILSFTLVSAIVLTTLATCCFLRRQKLSQQYKA", "length": 663 }, "evidence": [ { "id": "E1BAW2", "url": "https://omabrowser.org/oma/group/E1BAW2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FFN8-1", "protein_name": "Transforming growth factor beta activator LRRC32", "gene_name": "lrrc32", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGTCLWILMLMVSQVSPYRRPAEDSPCRVHQDDVDCSSLSLRRVPAPLPSSIRLLDLSQNLLQNLTLQDLPSRSSLRRLDLHHNQIQFLQPGLFRDLLHLEDLDLSGNALDLYAALHTPLGPLPALRRLDLSGNGLFTDMSDYFLSDAPALTNLSLDGNSITKISRTTFNGSQALQNIDLHNNVIIEIEEGAFEFLTELSELDLSVNSISCITDFNLVQLRTLNLSRNSLTNFQSLDMEDEFQLQHLDLRENKLLYFPVLPQRNRLMYLDLSRNLLRSVNCSGPLEELESLRESGYLLTAHDKPLTLCANERQQELGRLLYLDLSFNQLKTLSSSFFSSMAALESLNISNNCLQSFSVDSLRSLKTLDLSFNNLQNLSFSGGALPALEVLLLQGNALHLLDAHIFSSLPSIRSLHLQQNLLSICADPQISSGCVHLSDIPSLTYLYLSENSLSSIPDGAFKGSPLLILDLSLNPGVDITAASLSGVETSLTHLSLRGNQLHSLSIDFRVFQKLRSLDVSVNRLSGVSPWSEDSSVEILNLQNNRVEALGSALLQGRLRTLYVGWNPLSCCRNPQLLDLLQQERLHVPDLAAATCWYSGDVEQVEVSVSAALPELCSSADSRVLWVSLMVALALGLALVLTVSLKLCHSRKHRFKRGFKA", "length": 659 }, "evidence": [ { "id": "E1BAW2", "url": "https://omabrowser.org/oma/group/E1BAW2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SUL2-1", "protein_name": "Transforming growth factor beta activator LRRC32", "gene_name": "LRRC32", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSHQILLLLAMLTLGLASSQHRDKVPCKKVDKEASCQGLGLLQVPSMLARDIEALDLSGNQLRSIPASPLGFYVALRRLDLSANEISSLQPGAFQALPHLEHLNLAHNRLAQGMALGAGGLGPLPHLTALDLSGNSLYSGLAEQLLGEAPALRTLSLAENSLTRLARHTFRGAPALEWLDLHSNVLMDIEDGAFEALPRLAHLNLSRNSLTCISDFRLQQLRVLDLSCNSIEAFQTAPEPPAEYQLAWLDLRENRLLHFPDVTALPRLVYLNVSNNLIRLPEGPPQGGEGIHAPSEGWAALPASNPGRNASTPPLSQLLNLDLSYNEIELVPEGFLEHLTSLRFLNLSRNCLQAFRAWGAGSLPCLMRLDISHNALEKLELGAGALGSLRTLLLQDNALWDLPPYAFASLASLQRLNLQGNRISPCGGPGEPGPSGCVAFSGISSLRFLNLVDNKVETLRAGAFLHTPLTELDLSANPGLDVATGALAGLEGSLEVLALQGNGLATLQVDLPCFSCLKRLNLAENRLSRLPAWTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLTCHFGSQEAVSLSHVRPEDCEKGGLKNVNLVIILTFALVAAVLLTTLATCCCVRRQKFSQQYKA", "length": 663 }, "evidence": [ { "id": "E1BAW2", "url": "https://omabrowser.org/oma/group/E1BAW2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3XA59-1", "protein_name": "Transforming growth factor beta activator LRRC32", "gene_name": "Lrrc32", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHQILLLLAMLTLGLAISQRREQVPCRTVNKEALCHGLGLLQVPSVLSLDIQALYLSGNQLQSILVSPLGFYTALRHLDLSDNQISFLQAGVFQALPYLEHLNLAHNRLATGMALNSGGLGRLPLLVSLDLSGNSLHGNLVERLLGETPRLRTLSLAENSLTRLARHTFWGMPAVEQLDLHSNVLMDIEDGAFEALPHLTHLNLSRNSLTCISDFSLQQLQVLDLSCNSIEAFQTAPEPQAQFQLAWLDLRENKLLHFPDLAVFPRLIYLNVSNNLIQLPAGLPRGSEDLHAPSEGWSASPLSNPSRNASTHPLSQLLNLDLSYNEIELVPASFLEHLTSLRFLNLSRNCLRSFEARQVDSLPCLVLLDLSHNVLEALELGTKVLGSLQTLLLQDNALQELPPYTFASLASLQRLNLQGNQVSPCGGPAEPGPPGCVDFSGIPTLHVLNMAGNSMGMLRAGSFLHTPLTELDLSTNPGLDVATGALVGLEASLEVLELQGNGLTVLRVDLPCFLRLKRLNLAENQLSHLPAWTRAVSLEVLDLRNNSFSLLPGNAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFGSQEELSLSLVRPEDCEKGGLKNVNLILLLSFTLVSAIVLTTLATICFLRRQKLSQQYKA", "length": 663 }, "evidence": [ { "id": "E1BAW2", "url": "https://omabrowser.org/oma/group/E1BAW2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14392-1", "protein_name": "Transforming growth factor beta activator LRRC32", "gene_name": "LRRC32", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPQILLLLALLTLGLAAQHQDKVPCKMVDKKVSCQVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSHLPAWTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFSSQEEVSLSHVRPEDCEKGGLKNINLIIILTFILVSAILLTTLAACCCVRRQKFNQQYKA", "length": 662 }, "evidence": [ { "id": "E1BAW2", "url": "https://omabrowser.org/oma/group/E1BAW2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BAW2", "url": "https://www.uniprot.org/uniprotkb/E1BAW2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BAW2", "url": "https://www.uniprot.org/uniprotkb/E1BAW2" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E1BAW2", "url": "https://www.uniprot.org/uniprotkb/E1BAW2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "E1BAW2", "url": "https://www.uniprot.org/uniprotkb/E1BAW2" } ], "pmid": "" }, { "name": "secondary palate development", "id": "GO:0062009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062009", "evidence": [ { "database": "UniProtKB", "id": "E1BAW2", "url": "https://www.uniprot.org/uniprotkb/E1BAW2" } ], "pmid": "" }, { "name": "establishment of protein localization to extracellular region", "id": "GO:0035592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035592", "evidence": [ { "database": "UniProtKB", "id": "E1BAW2", "url": "https://www.uniprot.org/uniprotkb/E1BAW2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transforming growth factor beta binding", "id": "GO:0050431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050431", "evidence": [ { "database": "UniProtKB", "id": "E1BAW2", "url": "https://www.uniprot.org/uniprotkb/E1BAW2" } ], "pmid": "" }, { "name": "receptor ligand inhibitor activity", "id": "GO:0141069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141069", "evidence": [ { "database": "UniProtKB", "id": "E1BAW2", "url": "https://www.uniprot.org/uniprotkb/E1BAW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BAW2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 662, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BAW2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BAW2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 204, "end_pos": 206 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 309, "end_pos": 311 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 545, "end_pos": 547 }, { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "bile acid biosynthetic process", "id": "GO:0006699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006699", "evidence": [ { "database": "UniProtKB", "id": "E1BAX6", "url": "https://www.uniprot.org/uniprotkb/E1BAX6" } ], "pmid": "" }, { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "E1BAX6", "url": "https://www.uniprot.org/uniprotkb/E1BAX6" } ], "pmid": "" }, { "name": "B cell chemotaxis", "id": "GO:0035754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035754", "evidence": [ { "database": "UniProtKB", "id": "E1BAX6", "url": "https://www.uniprot.org/uniprotkb/E1BAX6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { 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"synonym", "evidence": [ { "id": "NP_001192366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192366" } ] }, { "name": "TRAPPC3L", "type": "synonym", "evidence": [ { "id": "NP_001192366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192366" } ] } ], "protein_names": [ { "name": "Trafficking protein particle complex subunit", "type": "recommended", "evidence": [ { "id": "E1BAY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAY8/entry#names_and_taxonomy" } ] }, { "name": "BET3 like", "type": "synonym", "evidence": [ { "id": "NP_001192366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192366" } ] }, { "name": "trafficking protein particle complex 3 like", "type": "synonym", "evidence": [ { "id": "NP_001192366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192366" } ] }, { "name": "trafficking protein particle complex subunit 3-like protein", "type": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF18026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193142", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193142", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BAZ9", "url": "https://www.uniprot.org/uniprotkb/E1BAZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAZ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BAZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAKSFASRLRGSRRFLSGFVAGAVAGAASTGLVVVQFLWSRDAEPAVVVREPDGSSEKAVLEQFGFPLAGTETRCYTNHALSYDQSKRVPRWVLEHISKSKITGAADRKHCKFKPDPNIPPAFSAFNEDYIGSGWSRGHMAPAGNNKFSTKAMAETFYLSNIVPQNFDNNAGYWNRIEMYCRELTERFEDVWIVSGPLTLPQTGSDGKKTVSYQVIGEDNVAVPSHLYKVILARRSAGSAEPLALGAFVVPNKAIGFQPQLSEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFREFTLYLSTRKVEGARSVVRLEKVLENLRNAGIEPDEYFMTRYEKKLEELRAQERSGVLEEKPS", "length": 368, "header": "tr|E1BAZ9-1|E1BAZ9_BOVIN Isoform 1 of Nuclease EXOG, 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"MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGSAEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQSGTQIRKPS", "length": 368 }, "evidence": [ { "id": "E1BAZ9", "url": "https://omabrowser.org/oma/group/E1BAZ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BAZ9", "url": "https://www.uniprot.org/uniprotkb/E1BAZ9" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { 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Expression" ] }, { "id": "IPR003347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RASICKC", "url": "https://omabrowser.org/oma/group/RASICKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10694", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10694", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10694:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10694:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3214842", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214842", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "60200", "url": "https://www.rhea-db.org/rhea/60200", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BB12-1", "url": "https://www.uniprot.org/uniprotkb/E1BB12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTDLFHCAQNPSCSIMIFHPTKEEFTDFDKYIAYIESQGAHRAGLAKIVPPKEWKARQTYDDINDILITAPLQQVVSGRAGVFTQYHKKKKAMTVAEYRHLANTEKYQTPFYSDFEELERKYWKTRLFESPIYGADISGSLFDENTKQWNLGRLGTIQDLLEQECGVVIEGVNTPYLYFGMWKTAFAWHTEDMDLYSINFLHFGEPKTWYAVPPEHGRRLERLAGALFPGSSRSCEAFLRHKAALISPTVLRDNGIPFGRVTQEAGEFMVTFPYGYHSGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEAQVAFSMDAFVRILQPERYELWKRGQDRAVVNHAEPAAPGGQELRAWKEVQTLGPKYFPPRRSARLRQPVSSSEGTDPRAPVRAVSLRPLPARGSCSASQFDAVAGSSSRKPSQTPPLLPGPSVASCLHPVGRCGSRRRPQEKGTQELTAPIGAKRGLALDRKAQDPKAQPLSAEGRMDNPAPTTEASSTGHSSDP", "length": 508, "header": "tr|E1BB12-1|E1BB12_BOVIN Isoform 1 of [histone H3]-trimethyl-L-lysine(9) demethylase OS=Bos taurus OX=9913 GN=KDM4D PE=3 SV=3 CANONICAL=E1BB12-1" }, "isoforms": [ { "isoform_ac": "E1BB12-1", "url": "https://www.uniprot.org/uniprotkb/E1BB12/entry#E1BB12-1", "sequence": { "sequence": "MKTDLFHCAQNPSCSIMIFHPTKEEFTDFDKYIAYIESQGAHRAGLAKIVPPKEWKARQTYDDINDILITAPLQQVVSGRAGVFTQYHKKKKAMTVAEYRHLANTEKYQTPFYSDFEELERKYWKTRLFESPIYGADISGSLFDENTKQWNLGRLGTIQDLLEQECGVVIEGVNTPYLYFGMWKTAFAWHTEDMDLYSINFLHFGEPKTWYAVPPEHGRRLERLAGALFPGSSRSCEAFLRHKAALISPTVLRDNGIPFGRVTQEAGEFMVTFPYGYHSGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEAQVAFSMDAFVRILQPERYELWKRGQDRAVVNHAEPAAPGGQELRAWKEVQTLGPKYFPPRRSARLRQPVSSSEGTDPRAPVRAVSLRPLPARGSCSASQFDAVAGSSSRKPSQTPPLLPGPSVASCLHPVGRCGSRRRPQEKGTQELTAPIGAKRGLALDRKAQDPKAQPLSAEGRMDNPAPTTEASSTGHSSDP", "length": 508, "header": "tr|E1BB12-1|E1BB12_BOVIN Isoform 1 of [histone H3]-trimethyl-L-lysine(9) demethylase OS=Bos taurus OX=9913 GN=KDM4D PE=3 SV=3 CANONICAL=E1BB12-1" }, "locus": { "chromosome": "15", "start_pos": 15419435, "end_pos": 15416391, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002234.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002234.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002234.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002234.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-3214842", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214842", "resource": "Reactome", "description": "HDMs demethylate histones" } ], "orthologs": [ { "uniprot_canonical_ac": "A1A5Q5-1", "protein_name": "Lysine-specific demethylase 4D", "gene_name": "Kdm4d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTKSTCAQNPNCSIMIFRPTKEEFNDFDKYIAYMESQGAHRAGLAKVIPPKEWRARQSYDNISNILIATPLQQVVSGQAGVFTQYHKKKKAMTVGQYRHLANSKKYQTPPHLDFEDLERKYWKNRLYESPIYGADVSGSLFDGKTQQWNVGHLGTIQDLLEQECGIVIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGQPKTWYAVPPEHGRRLELLAKELFPGSSQGCQAFLRHKVALISPTVLKENGIPFGRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVSFSMDAFVRILQPERYEMWKRGQDQAVVDHTEAMGPTSQELTTWRVIQAPRKTWGLKHLRLRQVSRCLLPVATDSNIANNTQMCHTSRQAADSKGDEVQESDPAIAPPYPLGLSSPGHMSTGKRGLGRRPCELGVQESTNGAPVKRRLPEGRDDRSPSPELQSQSVTGDLIVNSDLVNPGPQHPVTASEGGLTSDP", "length": 510 }, "evidence": [ { "id": "E1BB12", "url": "https://omabrowser.org/oma/group/E1BB12/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3U2K5-1", "protein_name": "Lysine-specific demethylase 4D", "gene_name": "Kdm4d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTKSTCAQNPNCSIMIFRPTKEEFNDFDKYIAYMESQGAHRAGLAKVIPPKEWRARQSYDNISNILIATPLQQVVSGQAGVFTQYHKKKKGMTVGEYRELANSKKYQTPPHLDFEDLERKYWKNRLYESPIYGADVSGSLFDGKTQQWNVGHLGTIQDLLEQECGIVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGQPKTWYAVPPEHGRRLERLARELFPGSSQGCQAFLRHKVALISPTVLKENGIPFGRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVSFSMDAFVRILQPERYELWKRGQDQAVVDHTETMVSTSQELTTRRVTKAPRKTWGLKRLRLRQVSRSLLPIATVSNVPCNMQVCHTSRQPSDVKGDDVQKSDSARASPHPLSLPSSGHMSTRRCSLGRRPCELGAQESSNGAPVKRQLPAGRDDTSPSPELQPQAVSGDLIVDSGLVNPGPQHLMTASEGGLTSDP", "length": 510 }, "evidence": [ { "id": "E1BB12", "url": "https://omabrowser.org/oma/group/E1BB12/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6B0I6-1", "protein_name": "Lysine-specific demethylase 4D", "gene_name": "KDM4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METMKSKANCAQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQDRAVVDHMEPRVPASQELSTQKEVQLPRRAALGLRQLPSHWARHSPWPMAARSGTRCHTLVCSSLPRRSAVSGTATQPRAAAVHSSKKPSSTPSSTPGPSAQIIHPSNGRRGRGRPPQKLRAQELTLQTPAKRPLLAGTTCTASGPEPEPLPEDGALMDKPVPLSPGLQHPVKASGCSWAPVP", "length": 523 }, "evidence": [ { "id": "E1BB12", "url": "https://omabrowser.org/oma/group/E1BB12/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V333-1", "protein_name": "Probable lysine-specific demethylase 4A", "gene_name": "Kdm4A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTRSSFADEEQNKVPRIMTFRPSYEEFQNFSAYIEYIESRGAHLAGLAKIQPPAEWVPRKSGYDIDNINMTIPAPICQVVTGAHGVYQQINIQQRRQMTLRQFMEKANSELHQTPRHFDYDDLERKYWKNITYISPLYAADVKGSLSDEDLDVWNIGRLDTILNLVNTDYNIIIDGVNTAYLYFGMWKSSFAWHTEDMDLYSINYLHFGAPKTWYAIPPAYGRRLEKLANETFSENYQECNAYLRHKMTMISPKVLRQHNIPYNKITQEAGEIMITFPFGYHAGFNHGFNGAESTNFASKRWIEYGKRASICRCRSDMVKISMETFVRRFQPERYDNWLKGQDMGCHPEEPGKICAAAPPTLNEYEKQENLRAAKSEEESPQKRGCSLAGNGCERNAESAEDVDDKASVSSYSSCRQLQPVVKLRKLPTIASVPEPSSAPKRYDFNTEAVVRVKRLWNELPCPDRGANLLTNGVVKNTKRMRFQTKVLTLDDED", "length": 495 }, "evidence": [ { "id": "E1BB12", "url": "https://omabrowser.org/oma/group/E1BB12/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" }, { "name": "histone H3K9 demethylase activity", "id": "GO:0032454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032454", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" }, { "name": "histone H3K9me2/H3K9me3 demethylase activity", "id": "GO:0140684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140684", "evidence": [ { "database": "UniProtKB", "id": "E1BB12", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60200", "name": "", "equation": "N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BPL5-1", "E1BA41-1", "A0AAA9SM03-1", "E1BB12-1" ], "evidence": [ { "id": "60200", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60200" } ] }, { "id": "R-BTA-4724279", "name": "KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BA41-1", "E1BPL5-1", "Q5EA24-1", "A0AAA9SM03-1", "E1BB12-1" ], "evidence": [ { "id": "R-BTA-4724279", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4724279" } ] }, { "id": "R-BTA-5661120", "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BA41-1", "E1BPL5-1", "Q5EA24-1", "A0AAA9SM03-1", "E1BB12-1" ], "evidence": [ { "id": "R-BTA-5661120", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5661120" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9SM03", "gene_name": "KDM4C", "activity": [ { "ec_number": "1.14.11.66", "activity": "N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "A0AAA9SM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SM03" } ] }, { "ec_number": "1.14.11.66", "activity": "", "evidence": [ { "id": "A0AAA9SM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SM03" } ] } ] }, { "uniprot_ac": "E1BA41", "gene_name": "KDM4B", "activity": [ { "ec_number": "1.14.11.66", "activity": "N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "E1BA41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA41" } ] }, { "ec_number": "1.14.11.66", "activity": "", "evidence": [ { "id": "E1BA41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BA41" } ] } ] }, { "uniprot_ac": "E1BB12", "gene_name": "KDM4D", "activity": [ { "ec_number": "1.14.11.66", "activity": "N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "E1BB12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ] }, { "ec_number": "1.14.11.66", "activity": "", "evidence": [ { "id": "E1BB12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB12" } ] } ] }, { "uniprot_ac": "E1BPL5", "gene_name": "KDM4A", "activity": [ { "ec_number": "1.14.11.69", "activity": "N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "E1BPL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPL5" } ] }, { "ec_number": "1.14.11.66", "activity": "N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "E1BPL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPL5" } ] }, { "ec_number": "1.14.11.69", "activity": "", "evidence": [ { "id": "E1BPL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPL5" } ] }, { "ec_number": "1.14.11.66", "activity": "", "evidence": [ { "id": "E1BPL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPL5" } ] } ] }, { "uniprot_ac": "Q5EA24", "gene_name": "RIOX2", "activity": [ { "ec_number": "1.14.11.-", "activity": "", "evidence": [ { "id": "Q5EA24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA24" } ] }, { "ec_number": "1.14.11.79", "activity": "L-histidyl-[protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-histidyl-[protein] + succinate + CO2.", "evidence": [ { "id": "Q5EA24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA24" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BB12-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 508, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BB12-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BB12" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BB12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB12" }, { "id": "PS51184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "JmjC", "eco_id": "ECO_0000259", "start_pos": 144, "end_pos": 310, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BB12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB12" }, { "id": "PS51183", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51183" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "JmjN", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 58, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.66", "ec_name": "N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "1.14.11.66", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.66" }, { "id": "1.14.11.66", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.66" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BB32-1", "uniprot_ac": "E1BB32", "uniprot_id": "E1BB32_BOVIN", "mass": { "chemical_mass": 67903.0, "monoisotopic_mass": 67903.0 }, "refseq": {}, "gene_names": [ { "name": "GP1BA", "type": "recommended", "evidence": [ { "id": "E1BB32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB32" } ] } ], "protein_names": [ { "name": "Glycoprotein Ib platelet subunit alpha", "type": "synonym", "evidence": [ { "id": "E1BB32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB32/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BB32", "url": "https://www.uniprot.org/uniprotkb/E1BB32" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GP1BA", "url": "https://www.uniprot.org/uniprotkb/E1BB32", "locus": { "chromosome": "19", "start_pos": 26460494, "end_pos": 26462445, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004909", "url": "https://www.ensembl.org/id/ENSBTAG00000004909" } ] } } ], "crossref": [ { "id": "E1BB32", "url": "https://alphafold.ebi.ac.uk/entry/E1BB32", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004909", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004909", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NPDFCCL", "url": "https://omabrowser.org/oma/group/NPDFCCL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BB32", "url": "https://www.uniprot.org/uniprotkb/E1BB32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BB32-1", "url": "https://www.uniprot.org/uniprotkb/E1BB32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLLLLLLLLPSPSHPVPICEVGNKDSQVEVNCENKGLKAPPPDLPADTAILHLGENPLGTFSMASVLNLSQLTELFLGKSQLTSLQADAKLPRLEVLNLAHNKLRSLPKLGRALPVLSILDVSFNELTSLPSDTLHGLSRLQELYLRGNQLRTLPPELLVPTPHLKKLSLAENDLQELPPELLKGLEELDTLYLQKNRLRTIPTDFFGMLLLPYAFFHNNSWSCDCGILYFSSWLQDNPSNVYVWEEDVDIKAMTPDVKSVRCVNMNGMYVYNFLGDSCNIPGDRDNLDYDEYEDKDEQEVPVVNTVSSLSSHTTHWDLLYLTSPTSPGSQVSSLPPVKKLTTTPITIDSITSSKTLNPTTEPPTTPTTPESTTPTTPEPTIPTTPEPTTPTTPEPTPRPPQKPTTPTTPEPTTPTTPEPTTPTTPEPTTPTTLEPTTPTTPEPISETLQPTIFLTSTESISLPTILESTITIISESDNPWKVQGLASSSNNPVLSSDSCCLFLGFYILGLLWLLVASVILILLLCWVQQVKPWALATATHTAHLELQRGRQVMVHRAWLLFFQGLLPTFRSSLFLWVRPNGRMGPLQAGRRPSALSLGRGGDLLGTVGVRYSGHSL", "length": 618, "header": "tr|E1BB32-1|E1BB32_BOVIN Isoform 1 of Glycoprotein Ib platelet subunit alpha OS=Bos taurus OX=9913 GN=GP1BA PE=4 SV=3 CANONICAL=E1BB32-1" }, "isoforms": [ { "isoform_ac": "E1BB32-1", "url": "https://www.uniprot.org/uniprotkb/E1BB32/entry#E1BB32-1", "sequence": { "sequence": "MPLLLLLLLLPSPSHPVPICEVGNKDSQVEVNCENKGLKAPPPDLPADTAILHLGENPLGTFSMASVLNLSQLTELFLGKSQLTSLQADAKLPRLEVLNLAHNKLRSLPKLGRALPVLSILDVSFNELTSLPSDTLHGLSRLQELYLRGNQLRTLPPELLVPTPHLKKLSLAENDLQELPPELLKGLEELDTLYLQKNRLRTIPTDFFGMLLLPYAFFHNNSWSCDCGILYFSSWLQDNPSNVYVWEEDVDIKAMTPDVKSVRCVNMNGMYVYNFLGDSCNIPGDRDNLDYDEYEDKDEQEVPVVNTVSSLSSHTTHWDLLYLTSPTSPGSQVSSLPPVKKLTTTPITIDSITSSKTLNPTTEPPTTPTTPESTTPTTPEPTIPTTPEPTTPTTPEPTPRPPQKPTTPTTPEPTTPTTPEPTTPTTPEPTTPTTLEPTTPTTPEPISETLQPTIFLTSTESISLPTILESTITIISESDNPWKVQGLASSSNNPVLSSDSCCLFLGFYILGLLWLLVASVILILLLCWVQQVKPWALATATHTAHLELQRGRQVMVHRAWLLFFQGLLPTFRSSLFLWVRPNGRMGPLQAGRRPSALSLGRGGDLLGTVGVRYSGHSL", "length": 618, "header": "tr|E1BB32-1|E1BB32_BOVIN Isoform 1 of Glycoprotein Ib platelet subunit alpha OS=Bos taurus OX=9913 GN=GP1BA PE=4 SV=3 CANONICAL=E1BB32-1" }, "locus": { "chromosome": "19", "start_pos": 26462445, "end_pos": 26460497, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006460.6", "url": "https://www.ensembl.org/id/ENSBTAT00000006460.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006460.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006460.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 398, "start_aa": "Thr", "end_pos": 398, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr398", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M4I1-1", "protein_name": "Platelet glycoprotein Ib alpha chain", "gene_name": "Gp1ba", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGIPSNSLCPQVHMALLILLFLLPSPLHSQPTCDVSKVTSLLEVNCEDKKLKKLPTDLPADTGILHLSKNQLGTFSTSYLVHFTHLTHLYLSRCELTSLQAHEKLLKLETLDLSHNHLQSLPSLGRALPALTTLDVSFNKLGSLSPGALEGLGQLEELYLQNNDLKSLPPGLLMPTTKLLKLSLANNKLRELPPGLLDGLEDLDTLYLQGNWLSTIPKGFFGSLLLPFVFLHANTWYCDCEILYFRNWLQENPNRVYLWKEGVDVKAMTANVASVRCANLGNAPVYSYPGKGCPTNEGDIDYDDYADTPTTRTEVKFSTNTKAHTTYWGLFYSESSTSPDSQMTSLPPIHEPTKKQPTFAHTEIPGFTTLPDTMESNTAFYSLNNTVPTTTPEPTSTQATPEPSSTPMLTTPVPTPEPSSIPMLTVPVSTPEPSSTPMLTTPVSTPEPSSIPMPTIPVPTPEPSSIPMPTIPVPTPEPSSTPMPTIPVPTPEPSSTPMFTTPVPTPEPSSTPMLTTPTLTTPESSSTPSILVSTIPPVLTTTLAPPESIPKTVLEQFYTLEPTLPRTLESTIIIPEQNSLNSQAVPQASSDTPKSNPFLNSDFCCLLPLGFYVLGLLWLLFASVVLIVLLTWIWHVTPHNLDMDQSAALATSTHTTSLEMQRARQVTMPWAWLLSLQGSLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGHGQDLLGRVGIRYSGHSL", "length": 731 }, "evidence": [ { "id": "E1BB32", "url": "https://omabrowser.org/oma/group/E1BB32/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35930-1", "protein_name": "Platelet glycoprotein Ib alpha chain", "gene_name": "Gp1ba", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLILLFLLPSPLHSQHTCSISKVTSLLEVNCENKKLTALPADLPADTGILHLGENQLGTFSTASLVHFTHLTYLYLDRCELTSLQTNGKLIKLENLDLSHNNLKSLPSLGWALPALTTLDVSFNKLGSLSPGVLDGLSQLQELYLQNNDLKSLPPGLLLPTTKLKKLNLANNKLRELPSGLLDGLEDLDTLYLQRNWLRTIPKGFFGTLLLPFVFLHANSWYCDCEILYFRHWLQENANNVYLWKQGVDVKDTTPNVASVRCANLDNAPVYSYPGKGCPTSSGDTDYDDYDDIPDVPATRTEVKFSTNTKVHTTHWSLLAAAPSTSQDSQMISLPPTHKPTKKQSTFIHTQSPGFTTLPETMESNPTFYSLKLNTVLIPSPTTLEPTSTQATPEPNIQPMLTTSTLTTPEHSTTPVPTTTILTTPEHSTIPVPTTAILTTPKPSTIPVPTTATLTTLEPSTTPVPTTATLTTPEPSTTLVPTTATLTTPEHSTTPVPTTATLTTPEHSTTPVPTTATLTTPEPSTTLTNLVSTISPVLTTTLTTPESTPIETILEQFFTTELTLLPTLESTTTIIPEQNSFLNLPEVALVSSDTSESSPFLNSDFCCFLPLGFYVLGLLWLLFASVVLILLLTWTWHVTPHSLDMEQSAALATSTHTTSLEVQRARQVTMPRAWLLFLQGSLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGRGQDLLGTVGIRYSGHSL", "length": 734 }, "evidence": [ { "id": "E1BB32", "url": "https://omabrowser.org/oma/group/E1BB32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07359-1", "protein_name": "Platelet glycoprotein Ib alpha chain", "gene_name": "GP1BA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLLLLLLLLPSPLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGNPWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCPTLGDEGDTDLYDYYPEEDTEGDKVRATRTVVKFPTKAHTTPWGLFYSWSTASLDSQMPSSLHPTQESTKEQTTFPPRWTPNFTLHMESITFSKTPKSTTEPTPSPTTSEPVPEPAPNMTTLEPTPSPTTPEPTSEPAPSPTTPEPTSEPAPSPTTPEPTSEPAPSPTTPEPTPIPTIATSPTILVSATSLITPKSTFLTTTKPVSLLESTKKTIPELDQPPKLRGVLQGHLESSRNDPFLHPDFCCLLPLGFYVLGLFWLLFASVVLILLLSWVGHVKPQALDSGQGAALTTATQTTHLELQRGRQVTVPRAWLLFLRGSLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGRGQDLLSTVSIRYSGHSL", "length": 652 }, "evidence": [ { "id": "E1BB32", "url": "https://omabrowser.org/oma/group/E1BB32/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BB32", "url": "https://www.uniprot.org/uniprotkb/E1BB32" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "E1BB32", "url": "https://www.uniprot.org/uniprotkb/E1BB32" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "blood coagulation, intrinsic pathway", "id": "GO:0007597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007597", "evidence": [ { "database": "UniProtKB", "id": "E1BB32", "url": "https://www.uniprot.org/uniprotkb/E1BB32" } ], "pmid": "" }, { "name": "fibrinolysis", "id": "GO:0042730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042730", "evidence": [ { "database": "UniProtKB", "id": "E1BB32", "url": "https://www.uniprot.org/uniprotkb/E1BB32" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "E1BB32", "url": "https://www.uniprot.org/uniprotkb/E1BB32" } ], "pmid": "" }, { "name": "positive regulation of platelet activation", "id": "GO:0010572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010572", "evidence": [ { "database": "UniProtKB", "id": "E1BB32", "url": "https://www.uniprot.org/uniprotkb/E1BB32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BB32-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 618, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BB32-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BB32" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BB32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB32" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 221, "end_pos": 281, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 398 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BB33-1", "uniprot_ac": "E1BB33", "uniprot_id": "E1BB33_BOVIN", "mass": { "chemical_mass": 76066.0, "monoisotopic_mass": 76066.0 }, "refseq": { "ac": "XP_010802163", "name": "Holliday junction recognition protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802163" }, "gene_names": [ { "name": "HJURP", "type": "recommended", "evidence": [ { "id": "E1BB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB33" } ] }, { "name": "HJURP", "type": "synonym", "evidence": [ { "id": "XP_010802163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802163" } ] } ], "protein_names": [ { "name": "Holliday junction recognition protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010802163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802163" } ] }, { "name": "Holliday junction recognition protein", "type": "synonym", "evidence": [ { "id": "E1BB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB33/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BB33", "url": "https://www.uniprot.org/uniprotkb/E1BB33" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HJURP", "url": "https://www.uniprot.org/uniprotkb/E1BB33", "locus": { "chromosome": "3", "start_pos": 113518138, "end_pos": 113529281, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024726", "url": "https://www.ensembl.org/id/ENSBTAG00000024726" } ] } } ], "crossref": [ { "id": "E1BB33", "url": "https://alphafold.ebi.ac.uk/entry/E1BB33", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024726", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024726", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617456", "url": "https://www.ncbi.nlm.nih.gov/gene/617456", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617456", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617456", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SFIAHSW", "url": "https://omabrowser.org/oma/group/SFIAHSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BB33", "url": "https://www.orthodb.org/?gene=E1BB33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15992", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15992", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15992:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15992:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12346", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12346", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-606279", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-606279", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-69273", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010802163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802163", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BB33", "url": "https://www.uniprot.org/uniprotkb/E1BB33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BB33-1", "url": "https://www.uniprot.org/uniprotkb/E1BB33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGEVLSEDELLMKLRDSRCRFQRRMQQLIEKYNQPFEDGPVIQMSTLTYQTPQGLRIWGGGLVKRSTGHMQGSPMKMDGRTDGSVRVPAGDLELPPPDTPANDSKSSDADTTFFQGEVIAGNLMPAVPWSPSKNELRRKYLTQVDILLQDEGCLEFQCAGYGEGKDTHVTLAPSLASPARPAQGYCKDISEDRPGGPLQPPPSPREGDASHSCSAGQAMMPRGDGIPLHGTGGGSFSSSPCSKGEDVCNATLSDLYAGMLHSMSRLLGARPSCIISTKTLIGQNWSFRRRHRCKGRMNRTSCRGGGRSRQSPQERRPPCSEPLEDAGTLRDRGNLPDVSVPKTDLKSGRALLKVNKPQIHTFTPPWKELQGMPQKHSSLTYLDSKVLSPLDQENRFVTLKWLISPVKIASRPRILRGQAGSRFKEIEIKFDKLHQEYCLSPGKQLSLTYPPGSAVDVYRGGPMSPGSPQGLEAHRLSSPLCKSKAKRLSEASEGLGRRSIRVGSCLPESESFPSLSKTNPTCSAGRPEHTVDLVCLGSDSGKFQESVSFSKAISVPRVQPLGFARDRYDDIKEKFDKLHRQYCQKSPQQTQAPSDKARAGVRYQKEGFSVKFNPDSGCRGPPSLSSSPQQSVKSPLASNTVGAPPSMDVALAAGSGHQVPTKRCRLSDPQVCGEGARPWSFSPVGRAMPRPGEEVDS", "length": 698, "header": "tr|E1BB33-1|E1BB33_BOVIN Isoform 1 of Holliday junction recognition protein OS=Bos taurus OX=9913 GN=HJURP PE=4 SV=3 CANONICAL=E1BB33-1" }, "isoforms": [ { "isoform_ac": "E1BB33-1", "url": "https://www.uniprot.org/uniprotkb/E1BB33/entry#E1BB33-1", "sequence": { "sequence": "MEGEVLSEDELLMKLRDSRCRFQRRMQQLIEKYNQPFEDGPVIQMSTLTYQTPQGLRIWGGGLVKRSTGHMQGSPMKMDGRTDGSVRVPAGDLELPPPDTPANDSKSSDADTTFFQGEVIAGNLMPAVPWSPSKNELRRKYLTQVDILLQDEGCLEFQCAGYGEGKDTHVTLAPSLASPARPAQGYCKDISEDRPGGPLQPPPSPREGDASHSCSAGQAMMPRGDGIPLHGTGGGSFSSSPCSKGEDVCNATLSDLYAGMLHSMSRLLGARPSCIISTKTLIGQNWSFRRRHRCKGRMNRTSCRGGGRSRQSPQERRPPCSEPLEDAGTLRDRGNLPDVSVPKTDLKSGRALLKVNKPQIHTFTPPWKELQGMPQKHSSLTYLDSKVLSPLDQENRFVTLKWLISPVKIASRPRILRGQAGSRFKEIEIKFDKLHQEYCLSPGKQLSLTYPPGSAVDVYRGGPMSPGSPQGLEAHRLSSPLCKSKAKRLSEASEGLGRRSIRVGSCLPESESFPSLSKTNPTCSAGRPEHTVDLVCLGSDSGKFQESVSFSKAISVPRVQPLGFARDRYDDIKEKFDKLHRQYCQKSPQQTQAPSDKARAGVRYQKEGFSVKFNPDSGCRGPPSLSSSPQQSVKSPLASNTVGAPPSMDVALAAGSGHQVPTKRCRLSDPQVCGEGARPWSFSPVGRAMPRPGEEVDS", "length": 698, "header": "tr|E1BB33-1|E1BB33_BOVIN Isoform 1 of Holliday junction recognition protein OS=Bos taurus OX=9913 GN=HJURP PE=4 SV=3 CANONICAL=E1BB33-1" }, "locus": { "chromosome": "3", "start_pos": 113528885, "end_pos": 113518164, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042677.4", "url": "https://www.ensembl.org/id/ENSBTAT00000042677.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040311.3", "url": "https://www.ensembl.org/id/ENSBTAP00000040311.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617456", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617456", "resource": "KEGG Pathway" }, { "id": "R-BTA-606279", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-606279", "resource": "Reactome", "description": "Deposition of new CENPA-containing nucleosomes at the centromere" }, { "id": "R-BTA-69273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69273", "resource": "Reactome", "description": "Cyclin A/B1/B2 associated events during G2/M transition" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A1W1-1", "protein_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESMNLRDRPLDQRLKESSRRFQTYMQRLIAKYNQPFEDDPLVQMATLTYETPQGLRVWGGKLIKEEDEEHTQDPSVEVIGGLSEQAPGGDSDSSGADTSLEEAEWPSCNLTREASGDTGKHQLTVPGNTLKTDLRRKYLTQVDILLQDAEYFKNTQKGDGKDTVTTCFPSWTSPVTPAPGCQDGIPAKSFGGPEGSASSCGDQASSYPCPADMTIVTRNDSFSLLGASSNSVSNQCPEVDDISNVTISDLYEGMMHSMSRLLRSKPSCIISTKTSINRNWKLKRRLSRKHGVHKNTTYCHRSKPFQRSSRKGPLHCSEPRKEARVLRDSKNLPHVDPHKTDKTGLELESVPLEGSKLQVHKLSPAWKELQGLPQKYLGLSTVNHLGREDRVKALQWLISPVKMAPRLRVPPGQVENWYREVKIKFEKLHQECCPSPEKRLRLTGPTQSWAADMYRGGSKSPGSRQSVETHKLSSPLSREKTERPGEAFEDLRGRSVKTNSCLLRRGPSPEDSPSQSPGHSQQRSGHLQEHNSEPIRKAAWPSTAISAPDFPDCGGHYDELKKEFNRLYQKYCLVSPRHAKVTLCGRLSPVKAAAAVPGQTEHLKRLNPDSPLQSSQKWSPSPDWRIRIPQDSTAVEGHRSAQTASAVVRGPWLSTKRRKLSYPAKSPDSSGAAGRL", "length": 677 }, "evidence": [ { "id": "E1BB33", "url": "https://omabrowser.org/oma/group/E1BB33/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SM16-1", "protein_name": "Holliday junction recognition protein", "gene_name": "HJURP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGEVCGEDELLQKLRDSRRRFQRRMQQLIEKYDQPFEDGPVVQMSTLTYETPQGFRIWGGGLVKERNPGQIQGFPAKADGGDNGHLQVTTRGPELSSPCTRVEDSKSSDVATTFYEEDIIAGSIMPAVPRSPLKDELRRKYLTQVDVLLREEGCLEGAGSGEGRDTCVTPVASLASPTRSAHGNCGVSEESLDGPVQPPSSPREGSALRPRPASVALVPRSDSISFPGTSGGSFSSSRCSEAEDICNATLSDLYAGMLHSMSRLLGARPCCIISTKTFIGQNWSSRRRHRCKSRMNRTSCRGGGRSRRSPRESRPPASEPRKHTAVLRDCENLLDVSGHKTGLEEGPSFLGVSKPHPPAFAPSWKGLQRTPPKLSSLTYLDSNAVYHLDQENRFMTLRWLISPVKITSRPRILQGQGRNRYREIELKFDKLHQEYCSSPQKQPGLTKLPSSSAVDVYRGRPAPPGGPWGLEACRLSSPLLRAKAKRLSEAFENLGQRSIKAGSCPPKSSAFPPLSKTDPTHSPGRSEHTADLVCRGQDLGRLRSVSPSKAISVPRVQPPGRAKDRYDDIKEKFDKLHQKYCPKSPQRTQVPSSPGAAPGEASVGVQYQKEFLGKFDPDSGSHGLPKPSPSPQWNIKSPLGSIAIEAPPSAGFALATRGRHEVPTKRRRLSEPLEGRRWSIPWDFSPVDRTTLRPGEEVGASQSDWEKKQRKEQHIFQDGREK", "length": 723 }, "evidence": [ { "id": "E1BB33", "url": "https://omabrowser.org/oma/group/E1BB33/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IET5-1", "protein_name": "Holliday junction recognition protein isoform X1", "gene_name": "Hjurp", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDPKDQPDNRLLRHLQESRNRFQTFMHRLIAKYNQPFEDDPLVQMSTLTYETPQGLRVWGGKLIKEKSKEQTQDSSMRMITRLNRQAPDSSEHLQPCIQVPGDDSESSGADTSADEEERLPGALMPTVPGSPLKNDLRWKYLTQVDILLQDEEYFKNAEKRNGKDTLMTFVSSSRVTPPPGCQDGISEKSFGSPQVSASSSRDWSTSNPCQADMTIMPRNDSFSFLGTSSSSLSSQPLEVDNICDVTVSDMYEGMMYSMSRLLSLKPSCIISTKTYINQNWNPRRRLSQKSRVHMNRTYSHRSKPFQRSSKKGPSSKPGKEVLRDCKNLLHTAPKTDLKLERGSLEGSKLQVYKFNPAWKELQVMPQKYLDLNTANYHEQENRVKTLQWLISPVKIVPRPGMLPSQAEKWYKEIEMKFDKLHQECSLSSEKQLPLAGPTESWAVDVYRGTSRSPGSPQGIKTHRLSSPFNRGKKRSSEAFEDISEMSVKADSCLPSGHPTLLPLGGNTSAGLFLQRHNFGPIRKAVSPSTANSVPWTSPWGHGRNRYDEIKEEFDKLYQKYCLMSPPQQVKMTSCVTVSSKKAGAAVPSQTEDLRKLNPDSGFQSSPKLSASGWNIRKPQDSIPVEAQMSARTAGAVMRDPRFPTKRRKLSYPPTCAH", "length": 658 }, "evidence": [ { "id": "E1BB33", "url": "https://omabrowser.org/oma/group/E1BB33/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6PG16-1", "protein_name": "Holliday junction recognition protein", "gene_name": "Hjurp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESMGRQDRRLHQQLKESSSRFQTLMKRLIAKYNQPFEDDPLVEMRTLTYETPQGLRVWGGKLMKKEDKEYTQVIDRLNGQAPEGDSESSGADTSLEENWPSCSSAMREASGDPRQRQPAVPGNTLETDLRRKYLTQVDILPQDEEYFKNAEKRGGKDTVMTWVPSVTSSVTPASGCQDAISAKSSGGPEVSALSSRGQGPSYPCPADMAIVARSDGLSLLGTSSNSVSSQSFEVDDLCNVTISDLYEGMMHSMSRLLRSKPSCIISTKTYINQSWKLRRRPSRKQGLHKNRTHCPRSKPSQRSARKGPASCSEPGKEAGILRDYGNLLHVAPHKTGLELKSVSLEGSKRQVHKSSPAWKELQMMPQKDLDLNRERENRVMTLQWLISPVKVVPRPRMLPSQVEKWYREIKIKFDKLHQEYCLSSGKQPRLTDPTESWAVDVYRSGSKSPGSRQDVETCRPSSPFGREKTERPGEALEDLRGNGKSVKTKSCLLRSCPSPEGSPSRSPSHSQLSSGLQEHNSEPTGKAVWPSTAISAPSIGSPGCGKDNYYELKKEFNRLYQKYCLSPQRAKVTSCGRVSPMKAAAALPCQSEHLKRLNPDSPQQSSQKRSISPGCHRRVLQDSTAQTASTLVRDSWLPTKRCKLSYPVACAHQAKFHDTSGASGWP", "length": 667 }, "evidence": [ { "id": "E1BB33", "url": "https://omabrowser.org/oma/group/E1BB33/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NCD3-1", "protein_name": "Holliday junction recognition protein", "gene_name": "HJURP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGTLRAMEGEDVEDDQLLQKLRASRRRFQRRMQRLIEKYNQPFEDTPVVQMATLTYETPQGLRIWGGRLIKERNEGEIQDSSMKPADRTDGSVQAAAWGPELPSHRTVLGADSKSGEVDATSDQEESVAWALAPAVPQSPLKNELRRKYLTQVDILLQGAEYFECAGNRAGRDVRVTPLPSLASPAVPAPGYCSRISRKSPGDPAKPASSPREWDPLHPSSTDMALVPRNDSLSLQETSSSSFLSSQPFEDDDICNVTISDLYAGMLHSMSRLLSTKPSSIISTKTFIMQNWNSRRRHRYKSRMNKTYCKGARRSQRSSKENFIPCSEPVKGTGALRDCKNVLDVSCRKTGLKLEKAFLEVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLDEENRFRTLKWLISPVKIVSRPTIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLPDSWAMNMYRGGPASPGGLQGLETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSDSSSSLPKTNPTHSATRPQQTSDLHVQGNSSGIFRKSVSPSKTLSVPDKEVPGHGRNRYDEIKEEFDKLHQKYCLKSPGQMTVPLCIGVSTDKASMEVRYQTEGFLGKLNPDPHFQGFQKLPSSPLGCRKSLLGSTAIEAPSSTCVARAITRDGTRDHQFPAKRPRLSEPQGSGRQGNSLGASDGVDNTVRPGDQGSSSQPNSEERGENTSYRMEEKSDFMLEKLETKSV", "length": 748 }, "evidence": [ { "id": "E1BB33", "url": "https://omabrowser.org/oma/group/E1BB33/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", 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[provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376847", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376847" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BB47", "url": "https://www.uniprot.org/uniprotkb/E1BB47#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BB47", "url": "https://www.uniprot.org/uniprotkb/E1BB47" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8A1F", "url": "https://www.uniprot.org/uniprotkb/E1BB47", "locus": { "chromosome": "29", "start_pos": 27930171, "end_pos": 27929254, "strand": "-", "evidence": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BB49-1", "uniprot_ac": "E1BB49", "uniprot_id": "E1BB49_BOVIN", "mass": { "chemical_mass": 69316.0, "monoisotopic_mass": 69316.0 }, "refseq": {}, "gene_names": [ { "name": "HIPK4", "type": "recommended", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BB49", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HIPK4", "url": "https://www.uniprot.org/uniprotkb/E1BB49", "locus": { "chromosome": "18", "start_pos": 49730332, "end_pos": 49738193, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040067", "url": "https://www.ensembl.org/id/ENSBTAG00000040067" } ] } } ], "crossref": [ { "id": "E1BB49", "url": "https://alphafold.ebi.ac.uk/entry/E1BB49", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000040067", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000040067", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "520157", "url": "https://www.ncbi.nlm.nih.gov/gene/520157", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:520157", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520157", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24058", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24058", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24058:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24058:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BB49", "url": "https://www.uniprot.org/uniprotkb/E1BB49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BB49-1", "url": "https://www.uniprot.org/uniprotkb/E1BB49-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLRCMRGLDPEEAHIIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLRALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAARKAHHFFKRNPHPDAANPWQLKSLADYLAETKVRPLERRKYMLKSLDQIETVNGVGAASRLTFPDREVLAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSTHETTRYYQLSLRSCRLSLQVEGKPPTSVLAAAEDGPPYYRLAEEEAAMGLGSTGGSGPFFREEKAPGMQRAIDQLDDLSLQEVGRGLWGETHADVVPDVLAPLKAAAVGRRLPESSPEPILAFYGTRLVGRHKVRKAPVGSKSDSNFSNLIRLSQASPEDDAPCRASGWAEGERLGASAEPPVIPQRDGDGPDIKDMTMDAESPGPELFDPNSCPGEWLSEPDWTLEGLRGPRVQGLPPHHAHPHGPPRATSFLQHVGGHH", "length": 616, "header": "tr|E1BB49-1|E1BB49_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=HIPK4 PE=3 SV=4 CANONICAL=E1BB49-1" }, "isoforms": [ { "isoform_ac": "E1BB49-1", "url": "https://www.uniprot.org/uniprotkb/E1BB49/entry#E1BB49-1", "sequence": { "sequence": "MATIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLRCMRGLDPEEAHIIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLRALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAARKAHHFFKRNPHPDAANPWQLKSLADYLAETKVRPLERRKYMLKSLDQIETVNGVGAASRLTFPDREVLAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSTHETTRYYQLSLRSCRLSLQVEGKPPTSVLAAAEDGPPYYRLAEEEAAMGLGSTGGSGPFFREEKAPGMQRAIDQLDDLSLQEVGRGLWGETHADVVPDVLAPLKAAAVGRRLPESSPEPILAFYGTRLVGRHKVRKAPVGSKSDSNFSNLIRLSQASPEDDAPCRASGWAEGERLGASAEPPVIPQRDGDGPDIKDMTMDAESPGPELFDPNSCPGEWLSEPDWTLEGLRGPRVQGLPPHHAHPHGPPRATSFLQHVGGHH", "length": 616, "header": "tr|E1BB49-1|E1BB49_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=HIPK4 PE=3 SV=4 CANONICAL=E1BB49-1" }, "locus": { "chromosome": "18", "start_pos": 49738067, "end_pos": 49730643, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052307.4", "url": "https://www.ensembl.org/id/ENSBTAT00000052307.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051851.4", "url": "https://www.ensembl.org/id/ENSBTAP00000051851.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:520157", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520157", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E1BB49", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "E1BB49", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BB49", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ], "pmid": "" }, { "name": "histone kinase activity", "id": "GO:0035173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035173", "evidence": [ { "database": "UniProtKB", "id": "E1BB49", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BB49", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BB49", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", 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"A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] } ] }, { "uniprot_ac": "A0A3Q1LWT7", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] } ] }, { "uniprot_ac": "A0A3Q1LYH3", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] } ] }, { "uniprot_ac": "A0A3Q1M1Z0", "gene_name": "ULK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] } ] }, { "uniprot_ac": "A0A3Q1M2U5", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2U5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2U5" } ] } ] }, { "uniprot_ac": "A0A3Q1M334", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] } ] }, { "uniprot_ac": "A0A3Q1M4N6", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] } ] }, { "uniprot_ac": "A0A3Q1M4X3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] } ] }, { "uniprot_ac": "A0A3Q1M5T5", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5T5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5T5" } ] } ] }, { "uniprot_ac": "A0A3Q1M614", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M614" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M614" } ] } ] }, { "uniprot_ac": "A0A3Q1M6N5", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M6N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6N5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M6N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6N5" } ] } ] }, { "uniprot_ac": "A0A3Q1M9F0", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M9F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M9F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9F0" } ] } ] }, { "uniprot_ac": "A0A3Q1M9L7", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L7" } ] } ] }, { "uniprot_ac": "A0A3Q1MA37", "gene_name": "CDC42BPG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MA37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MA37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA37" } ] } ] }, { "uniprot_ac": "A0A3Q1MD82", "gene_name": "CDK16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] } ] }, { "uniprot_ac": "A0A3Q1MEZ6", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MHH5", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] } ] }, { "uniprot_ac": "A0A3Q1MHL3", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { "uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { 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"ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": 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] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": 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"evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q58D94", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] } ] }, { "uniprot_ac": "Q8MIT6", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] } ] }, { "uniprot_ac": "Q95KV0", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] } ] }, { "uniprot_ac": "Q9N0P9", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] } ] }, { "uniprot_ac": "V6F977", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BB49-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 616, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BB49-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BB49" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 347, "start_aa": "Tyr", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 501, "end_pos": 503 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BB53-1", "uniprot_ac": "E1BB53", "uniprot_id": "E1BB53_BOVIN", "mass": { "chemical_mass": 294743.0, "monoisotopic_mass": 294743.0 }, "refseq": { "ac": "XP_005211524", "name": "telomerase protein component 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211524" }, "gene_names": [ { "name": "TEP1", "type": "recommended", "evidence": [ { "id": "E1BB53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB53" } ] }, { "name": "TEP1", "type": "synonym", "evidence": [ { "id": "XP_005211524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211524" } ] } ], "protein_names": [ { "name": "Telomerase associated protein 1", "type": "synonym", "evidence": [ { "id": "E1BB53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB53/entry#names_and_taxonomy" } ] }, { "name": "telomerase protein component 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005211524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211524" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BB53", "url": "https://www.uniprot.org/uniprotkb/E1BB53" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TEP1", "url": "https://www.uniprot.org/uniprotkb/E1BB53", "locus": { "chromosome": "10", "start_pos": 26748582, "end_pos": 26707954, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001179", "url": "https://www.ensembl.org/id/ENSBTAG00000001179" } ] } } ], "crossref": [ { "id": "ENSBTAG00000001179", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001179", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505802", "url": "https://www.ncbi.nlm.nih.gov/gene/505802", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BB53", "url": "https://www.orthodb.org/?gene=E1BB53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44791", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44791", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44791:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44791:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05731", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05731", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005211524", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211524", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BB53", "url": "https://www.uniprot.org/uniprotkb/E1BB53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BB53-1", "url": "https://www.uniprot.org/uniprotkb/E1BB53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 2656, "header": "tr|E1BB53-1|E1BB53_BOVIN Isoform 1 of Telomerase associated protein 1 OS=Bos taurus OX=9913 GN=TEP1 PE=4 SV=5 CANONICAL=E1BB53-1" }, "isoforms": [ { "isoform_ac": "E1BB53-1", "url": "https://www.uniprot.org/uniprotkb/E1BB53/entry#E1BB53-1", "sequence": { "sequence": 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"length": 2656, "header": "tr|E1BB53-1|E1BB53_BOVIN Isoform 1 of Telomerase associated protein 1 OS=Bos taurus OX=9913 GN=TEP1 PE=4 SV=5 CANONICAL=E1BB53-1" }, "locus": { "chromosome": "10", "start_pos": 26748469, "end_pos": 26715050, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001564.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001564.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001564.7", "url": "https://www.ensembl.org/id/ENSBTAP00000001564.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BB53", "url": "https://www.uniprot.org/uniprotkb/E1BB53" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "E1BB53", "url": "https://www.uniprot.org/uniprotkb/E1BB53" } ], "pmid": "" }, { "name": "telomerase holoenzyme complex", "id": "GO:0005697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005697", "evidence": [ { "database": "UniProtKB", "id": "E1BB53", "url": "https://www.uniprot.org/uniprotkb/E1BB53" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "E1BB53", "url": "https://www.uniprot.org/uniprotkb/E1BB53" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "E1BB53", "url": "https://www.uniprot.org/uniprotkb/E1BB53" } ], "pmid": "" }, { "name": "telomerase activity", "id": "GO:0003720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003720", "evidence": [ { "database": "UniProtKB", "id": "E1BB53", "url": "https://www.uniprot.org/uniprotkb/E1BB53" } ], "pmid": "" }, { "name": "telomerase RNA binding", "id": "GO:0070034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070034", "evidence": [ { "database": "UniProtKB", "id": "E1BB53", "url": "https://www.uniprot.org/uniprotkb/E1BB53" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "telomere maintenance via recombination", "id": "GO:0000722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000722", "evidence": [ { "database": "UniProtKB", "id": "E1BB53", "url": "https://www.uniprot.org/uniprotkb/E1BB53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1021, "end_pos": 1023, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1735, "end_pos": 1737, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2395, "end_pos": 2397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 703, "end_pos": 705, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BB53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB53" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 1200, "end_pos": 1468, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BB53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB53" }, { "id": "PS50988", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50988" } ], "ann_type": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BB54-1", "uniprot_ac": "E1BB54", "uniprot_id": "E1BB54_BOVIN", "mass": { "chemical_mass": 120241.0, "monoisotopic_mass": 120241.0 }, "refseq": { "ac": "XP_002691857", "name": "SUMO-specific isopeptidase USPL1 isoform X1", "summary": "", "url": 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{ "database": "UniProtKB", "id": "E1BB54", "url": "https://www.uniprot.org/uniprotkb/E1BB54" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "USPL1", "url": "https://www.uniprot.org/uniprotkb/E1BB54", "locus": { "chromosome": "12", "start_pos": 30183879, "end_pos": 30209595, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001178", "url": "https://www.ensembl.org/id/ENSBTAG00000001178" } ] } } ], "crossref": [ { "id": "E1BB54", "url": "https://alphafold.ebi.ac.uk/entry/E1BB54", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001178", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001178", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "788351", "url": "https://www.ncbi.nlm.nih.gov/gene/788351", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:788351", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788351", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NANALCW", "url": "https://omabrowser.org/oma/group/NANALCW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BB54", "url": "https://www.orthodb.org/?gene=E1BB54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15294", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15294", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15294:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15294:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15509", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15509", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002691857", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691857", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BB54", "url": "https://www.uniprot.org/uniprotkb/E1BB54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BB54-1", "url": "https://www.uniprot.org/uniprotkb/E1BB54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDSPKSGNGLPMVGPGPDIGNSSLHMVGYLGKNYDSVKVLSDGYCPACRAKGKLKALKTYRISFQESVSLCEDLQCIYPLGSKSLNNLFSPGLEDCHTPNKSQKRKILETNCEDSPLLAGSKKTKNHRGIDSEQVLNSNHNGGEYDGTSPDLPGSLYSGQQNPVRTAGCWEQNEALEADTVDMASEEDAPMVDVSGTEGTRPQNERCTSELEKPLESKHTSLCQTSCVQWKNAHALCWLDCILSALVHLEGLKSTVTDLQSKEESVFGRLFTRYSEANKLLHTSQLDGVKDGDCKKLPSEIFAKIETCLNEVRDEIFIRLQPQLRCTLGDMESPVFAFPLLLKIEPHIEQLFTYSFSWNFECSHCGHKYQNRCMKNLVTFTNVIPEWHPLKAAHFGPCNNCNNKSQIRKMVLEKVSLVFMLHFVEGLPHNDLQRYSFHSEGCLYQVTSVIQYQANNHFVTWILDADGSWLECDDLKGLCSERHETFQVPASEIHIVIWERKTSQMTDKAPACHPLKKTSDQYAFGDEKQVFPAACSAGEAASAEPSSGTHPTDVSMVPNTLSQDEAVAPGRHSLPNLKGSVDSGILPLTLEEVQSNSEGFLLEHKPVAENAGVVEANTLQSEEPLIALLVAPFEDKLTHNQPDLSFSSQLLTMPSVQVSTEDTAVTQPVNDTQAGGLIQQVKPVDTEGAVALERNASLKQFLVAETEKLNPEQHVTSQVSDWKEKETTAFSQTVTAKPLQNPPLKENQKKPFVGSWVKGLLSKGVSFMPSCVSAHNRNTVTDLQPSVKGASNFGGFQTKGSRQKASQASRKAHRRAAKPPLLSNSPPSHQSPTSTASPPRADGTGDSEVWKRCESASCGAYLNHNSHGNENGVSSPNHGDTIEGQIHKLRLKLLKKLKAKKKKLASLMSSPQNGTLPSEPSEQVSHCGSPNDSESIEGLLQELQRQIDIADNKSGCATVPGVSPYGGQTHEEILAELLSPATVVSTELSENGEADFRYLEMGDSHIPAPVPNELNSIAHNTHLRQEHNYCSPKKNQSELQPDSLTNNAFIRTLNLESPMKTDIFDEFFSASALNSLANDTLDLPHFDEYLFENC", "length": 1095, "header": "tr|E1BB54-1|E1BB54_BOVIN Isoform 1 of Ubiquitin specific peptidase like 1 OS=Bos taurus OX=9913 GN=USPL1 PE=4 SV=1 CANONICAL=E1BB54-1" }, "isoforms": [ { "isoform_ac": "E1BB54-1", "url": "https://www.uniprot.org/uniprotkb/E1BB54/entry#E1BB54-1", "sequence": { "sequence": "MTDSPKSGNGLPMVGPGPDIGNSSLHMVGYLGKNYDSVKVLSDGYCPACRAKGKLKALKTYRISFQESVSLCEDLQCIYPLGSKSLNNLFSPGLEDCHTPNKSQKRKILETNCEDSPLLAGSKKTKNHRGIDSEQVLNSNHNGGEYDGTSPDLPGSLYSGQQNPVRTAGCWEQNEALEADTVDMASEEDAPMVDVSGTEGTRPQNERCTSELEKPLESKHTSLCQTSCVQWKNAHALCWLDCILSALVHLEGLKSTVTDLQSKEESVFGRLFTRYSEANKLLHTSQLDGVKDGDCKKLPSEIFAKIETCLNEVRDEIFIRLQPQLRCTLGDMESPVFAFPLLLKIEPHIEQLFTYSFSWNFECSHCGHKYQNRCMKNLVTFTNVIPEWHPLKAAHFGPCNNCNNKSQIRKMVLEKVSLVFMLHFVEGLPHNDLQRYSFHSEGCLYQVTSVIQYQANNHFVTWILDADGSWLECDDLKGLCSERHETFQVPASEIHIVIWERKTSQMTDKAPACHPLKKTSDQYAFGDEKQVFPAACSAGEAASAEPSSGTHPTDVSMVPNTLSQDEAVAPGRHSLPNLKGSVDSGILPLTLEEVQSNSEGFLLEHKPVAENAGVVEANTLQSEEPLIALLVAPFEDKLTHNQPDLSFSSQLLTMPSVQVSTEDTAVTQPVNDTQAGGLIQQVKPVDTEGAVALERNASLKQFLVAETEKLNPEQHVTSQVSDWKEKETTAFSQTVTAKPLQNPPLKENQKKPFVGSWVKGLLSKGVSFMPSCVSAHNRNTVTDLQPSVKGASNFGGFQTKGSRQKASQASRKAHRRAAKPPLLSNSPPSHQSPTSTASPPRADGTGDSEVWKRCESASCGAYLNHNSHGNENGVSSPNHGDTIEGQIHKLRLKLLKKLKAKKKKLASLMSSPQNGTLPSEPSEQVSHCGSPNDSESIEGLLQELQRQIDIADNKSGCATVPGVSPYGGQTHEEILAELLSPATVVSTELSENGEADFRYLEMGDSHIPAPVPNELNSIAHNTHLRQEHNYCSPKKNQSELQPDSLTNNAFIRTLNLESPMKTDIFDEFFSASALNSLANDTLDLPHFDEYLFENC", "length": 1095, "header": "tr|E1BB54-1|E1BB54_BOVIN Isoform 1 of Ubiquitin specific peptidase like 1 OS=Bos taurus OX=9913 GN=USPL1 PE=4 SV=1 CANONICAL=E1BB54-1" }, "locus": { "chromosome": "12", "start_pos": 30206218, "end_pos": 30184883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001562.5", "url": "https://www.ensembl.org/id/ENSBTAT00000001562.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001562.3", "url": "https://www.ensembl.org/id/ENSBTAP00000001562.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:788351", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788351", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LEA5-1", "protein_name": "Ubiquitin specific peptidase like 1", "gene_name": "Uspl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKFRYCTDYTWRKGNEDNLFLDKLKFENHPGVLYINQCLEDLESLLLNYASAKVPADGYCPTCRAKGKLNTLKTYRISFQESIFLCEDLQCIYPLGSESLTNLISPDSEDCHTPNKPQKRKRLEDNCKNSSLPVHSKKTRGHLVTDSDQIVNGECNGEVCGDFSASFPGDSAHQDPARTAASVGQNGTLEANDNVVMATTEDPAAVGVTPELEMPSESRCLSLCQPLCVQWRNTQALCWLDCILSALVHLEVLRDAVLEVCSREECVFGKLFETYHQADKLLYTHHLHGVTGEDCKKMTTEIFTEIDTSLNKIRDEIFAKLQPKLRCTLGDMESPVFALPVLLKLEPHVENLFTYSFSWNFECSHCGHQYQNRCVKSLVTFTNVVPEWHPLNAAHFGPCNSCNSKSQIRKMVLERASPIIMLHFVEGLPRKDLQHYAFHFEGSLYQVTSVIQYRAKNHFITWTVDADGSWLECDDLKGPCAKRHEACEVPASETHIVIWERKSQVPVEGAACLPHMKLHVQSVSGEEQPSSLAGTATSEPSVAHPTPMAVAPQILPATQAVAHGDSVLSGTGGLLDSVSPSALEETIQETASVSQIDSKDCLLEDKPVVGSAGPVRTLTFQPQDSLGSSLVLNLCEGMLVAPCVDSRFPSQAVSTGLQAVPSQAGDTVVPKPVTDAPVPVLVQELKSMATEDSQTQLLPLKTDRLNPGQPPGKTQASNLRKRENAASSKPVAARSAQNQPRKDEQKKAFVGSWVKGLLSRGGAFMPPCVSAQSRAVTDLQPSVKGANNFDGFKTKSINRRSKRMSRKAKHVEEASPGSSPPLSGSTAALPQAAGNASSAQLKEQEGSRSAPLSHRPPSDESAMSPAGRAEAAEDQVHKLRLRLLKKLKAKKKKLAALMSSPRREPSVSDHSEPASHCGSPNDCDAVEDLLRELQYQIDLADNKSGCTSAPDGTSCNSQSHEEILAELLSPTALSEPSESGEPELRYLEMGDNSTPTPAPSEFSAVSQNTCLNQEHNYCSPEKSQCEVDLHSVIDSACVRALNLGSPMKTDIFDDFFPTSALNSLTNDTLDIPHFDDSLFENC", "length": 1083 }, "evidence": [ { "id": "E1BB54", "url": "https://omabrowser.org/oma/group/E1BB54/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BT05-1", "protein_name": "Ubiquitin specific peptidase like 1", "gene_name": "USPL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDTQKTTNGLRVIGQGTGIGKSTLHMVGYLGKSHAPVEKTSPDYCPVCKEKGQVQVLRTYRINFQESIYLCENPQCIYPLGYKPFNSIIISADSENLQVPSYDKKRKLCDISDLSPIESNPKQARTNNVVNVEQAINTDPVVKSCGDSLCIPQSRVCDVLENGQQKSNSEESINQKVDFETTSNTNGHQESPPKNFSSRTQLLPNSTHSSTASEVLLRDNNCSTNNTELCLQWRNKYNLCWLDCVLSALVHLEALKFALVEEDDEKCLLQRLLTKYSQATVLLNTCKRGKVKDILPKAELLLNEIRNQIFIQLQPQLKCELGKEESPVFALPLLLKQDQHAEKLFSHSFSWKFECMCCGYKYLDRCRKTLTTFTNIIPDWHPLNAVHVAPCNNCSDRSQRRQMILEKVPSILMFHFQEGLPHNKLKSYSFQLEEDVYQITSVIQYAVHKKHFITWSLNPDGTWLECDDLKGPYCRRHKRFEVPPTEIHIVIWEKKASRLPEEQDSQYQSKNIEDSSTNNVQLKSTVLHCGFDDAVDNMLAEDHQEDTVRIPDKKQQRVAEGESSARCGLENLARDGLVTQILEETPLDSEGKSMLSRKMVENNLVVETGSQEKQESAFSPNTPCTGEFIATDLAMNDKDMLSENSSMCLSLQELNPASITSSVPKKHDPNPSDSSLAQSTGDRANLINGEHGLSSGQQINCELPPVENIVQKSPDLTGASKTAVHSQVASSSVDNNSFQPSDKDQKRGFVGSWVKKLLSKNTSFLPSSASLPKNERSCKTPSVQKLSDTWLPVKGASNFGGFQGRGERKSSQTLTSVLPRSNNAQCLSKFQGFSQGTCLPRSHSAKEGPTWNKSGNTQGGSGKTTQVHPPSCNSVKAEESDSDKTRKLRLKLLKKLNAKKKKLASLDRLAVEQAKRGKPVARDVSAPSQTESHNDSELLQSFLRELQYHIDAADNSSEFSVNSGCTSHNSNDEILAELLSPASTVASSEVPKSEDECMYMEMVNSSSAAPAEPAEKTSVSHAAVTSEDRSYYGPVKDSNYERTVSKSSVKKTGFESPTREDILEDLFSISAPTTMAGDMDVPHFDETLFETW", "length": 1092 }, "evidence": [ { "id": "E1BB54", "url": "https://omabrowser.org/oma/group/E1BB54/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GWG1-1", "protein_name": "SUMO-specific isopeptidase USPL1 isoform X1", "gene_name": "Uspl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESLKIGNGLPRVGPGTDIGISSLPKLGYLGKNYDSAKVTTDGQCPACRAKGKLNNLKTYQINFQESIFLCEDLQCIYPLGSESLTNLISPDSGDCHTQNKPQKRKRLETNAKSSPLPVHSKKTRNHVVTDGEQNLNAKYNGKVCGDTSSNLPDNTSHQNHVRAVASSEQNETLEVDTVDTLDVDTVDVSTKEDPATVSVFGVLTQSQGSELEMPSESRCLPFCQTLCVQWRNSQALCWLDCILSALVHLEALRNTVMEVCSREECVFGRLFETYHQADKLLYTHHLHGVTGEDCKQLRSEILAEIETCLNGVRGEIFTKLQPKLRCTLGEMESPVFAFPALLKLEPHVEKLFTYSFSWNFECSNCGHQYQNRCLKSLVTFTNVVPEWHPLNAAHFGPCNSCNSKSQIRKMVLERASPIFMLHFVEGLPRKDLQHYAFHFEDSLYQVTCVIQYQANNHFITWIVEADGSWLECDDLKGSFAKRHVTCEVPASEIHIVVWERKSQVPTEEATCLPCTKPSAQPASGEEQPASPTLCSVGGAATSEPSVAHLTHMPVAPQTLPEVQAVAHGDSVLSGTKGLVEAASVFQVDFKDCLLEDKPVAESAELVRALSLQPQDSLMTSLLSNPYEGKLVTPPVVSTDPEAVPSQAGDTVIPNSVTDAPVPVPVQELKSMVAEKDTQIQLLPLSAERLKPAQPAKSQASNVRKRETAASSKTVMASSLQTQPQKDDQKKAFVGSWVKGLLSRGGSFMPPCVLAQNRAVTDLQPSVKGANNFDGFKTKNVNRKAKRMSRKASKHVDEPTAGSCSPPSGSTATLPHAGGNATSILLKGQESSRATPLSNNLHSSESVISPASCGDAAEDQVHKLRLKLLKKLKAKKKKLAALMSSPNRGTSVSDHSEPVSHCGSPNDCESIEDLLNELQYQIDLADNKSGCTTAPDGTSCNSQSHEEILAELLSPPALSEPSASVESELRYLEVGDSTPAPTEFNAVSQSICLGQDHNYCSPKKNQCEAEVQSLTDSACIRALNLGSPMKTDIFDDFFPTSALNSLANDTLDIPHFDEYLFENC", "length": 1064 }, "evidence": [ { "id": "E1BB54", "url": "https://omabrowser.org/oma/group/E1BB54/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LMI0-1", "protein_name": "Ubiquitin specific peptidase like 1", "gene_name": "USPL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMDSPKIGNGLPVIGPGPDIGISPLHMVGYLGKNCDSAQVPSDGYCPACRTKGKLKALKSYRISFQESVFLCEDLQCIYPLGSKSLNNVISPDLEDCHTPNKPQKRKILETNSSDSPLLANSKKTKNHIGIDGEQVLNSKHNEEERDETSSDVPGLLPDCQQNPVRTADSLEQNEILEADIDVATEEDFTTVDASATGGSSPQNEGCTSELEVPLESKRTSFCQTSCVQWKNTHALCWLDCILSALVHLEGLKNTVTDLCSEEESVFRRLFTRYNQANELLLTSQSDGVKGGECKKLHSEIFPKIETCLNEVRDEIFIRLQPQLRCTLGDMESPVFAFPLLLKIEPDIERLFTYSFSWNFECSHCGHKYQNRCMKNLVTFTNVIPEWHPLNAAHFGPCNNCNNKLQIRKMVLEKVSPMFMLHFVEGLPHNDLQRYAFHAEGCLYQISSVIQYQANNHFITWILDADGCWLECDDLKGLCSERREKFKVPASEIHIVIWERKASQMTDKASASQPLKKPSDQHAFGDEKPASPALCHLGDAASAEMALGTYPTNVSVAPNTLSQDDAIAIGHHLLSSPKGLADSMLPLTLQEIQVNSEGFLLENKAVAENAGVVKTDTLQSQESLIASLVSAPCKDKLTQDQRVDLSFSSQLVNMKMPSIQPNTEDTVVCKPVNGIHAADPIQEVTSVEIEGTVALEKDAPSKQFLSPKTEKIKPEQHVTSQVSDLKEKETAAFSQTVTAKSLQNPALKENQKKPFVGSWVKGLLSKGASFMPPCVSAHNRNAITDLQPSVKGASNFGGFKTKGSKQKANRASRKAPRCAGKGPPVSTPPPSQPSAVSPASLHGNGHVDLLKKCENASYGSHLNHSSHGSENGVSSANHRDSAEDQVHKLRLKLLKKLKAKKKKLAALMSSPQNGALAGENSEPVSHCGSPNDCESIEDLLKELQYQIDIADSKSGCTTVPSVSPYSGQTHEEILAELLSPTTAVATELSEHGEADFRYLEMGDNHIPAPEPNELNSIPQNTHLRQDHNYCSPTKKSHCEVQPDSLTNNACLRTLNSESPMKTDIFDEFFSPSALNSLANDTLDLPHFDEYLFENC", "length": 1095 }, "evidence": [ { "id": "E1BB54", "url": "https://omabrowser.org/oma/group/E1BB54/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3ULM6-1", "protein_name": "SUMO-specific isopeptidase USPL1", "gene_name": "Uspl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDDSLKIGNGLPLVGPGTDVGISSLPMLGYLGKNYASAKVTTDGHCPACRAKGKLSALKPYRISFQESVFLCEDLQCIYPLGSESLTNLISPDSEDCPTPSKPQKRKRLETNCRNSPLPVHSKKTRSHIVTDSEPIVNGKYNGEVCDDFSASFPDTSAHQDPASTAASVEQSEALEADDVVVAATEDPATVSVTSELEMPAKSRCLPLCQTLCVQWKNTQALCWLDCILSALVHLEVLRKTVLEACSREECVFGRLFEMYHQADELLHTHHLHGVTGEDCKKLTSEIFTEIDTCLNKVRDEIFAKLQPKLRCTLGDMESPVFALPVLLKLEPHVESLFTYSFSWNFECSHCGHQYQNRCVKSLVTFTNIVPEWHPLNAAHFGPCNSCNSKSQIRKMVLERASPILMLHFVEGLPRRDLQHYAFHFEGSLYQVTSVIQYQANNHFITWFLDADGSWLECDDLKGPCAKRHVTCEVPASETHIVIWERKSQVPIEEAACLPCMKPNVQPVSGEEQPTCPALCSLAGTATSEPSVAHPTSMAGAPQTLPEIQAVAHGDSVLSGAKGMVDSILPSALEETIQETASVSQVDSKDCLLEDKPVAGSAALVRVLAFQPQDSPGSSGSSLVSSLCEGKLVAPCVDSSFPSQAVSTDLQAVLSQAGDTVVPNPVTDAPVPVLVQELKSLATEKDSQTQLLPLKTEKLDPEQPGKSQASNLRKRETTASSKTVAARSAQNQPRKEDQKRAFVGSWVKGLLSRGGAFMPTCVLSQSRAVSDLQPSVKGASNFDGFKTKSISRRSKRMSRKAKHMEELSPRNSSPPLSWTAALTQAAENATSALLREQEGSRPAPLRHRSPGNESAISPASRGDAAEDQVHKLRLKLLKKLKAKKKKLAALISSPHREPSLSDHSEPASHCGTPASDQSEPVSHCGSPNDCESIEDLLKELQHQIDLADSKSGCTSAPDATSNNSQSHEEILAELLSPTAMSEPSESGELELRYLEMGDSTPAQAPSEFSVVSLNTCLKQDHDYCSPEKGQREVDLHSVMDSACIRTLNLGSPMKTDIFDDFFSTSALNSLTNDTLDIPHFDDSLFENC", "length": 1089 }, "evidence": [ { "id": "E1BB54", "url": "https://omabrowser.org/oma/group/E1BB54/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5W0Q7-1", "protein_name": "SUMO-specific isopeptidase USPL1", "gene_name": "USPL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMDSPKIGNGLPVIGPGTDIGISSLHMVGYLGKNFDSAKVPSDEYCPACREKGKLKALKTYRISFQESIFLCEDLQCIYPLGSKSLNNLISPDLEECHTPHKPQKRKSLESSYKDSLLLANSKKTRNYIAIDGGKVLNSKHNGEVYDETSSNLPDSSGQQNPIRTADSLERNEILEADTVDMATTKDPATVDVSGTGRPSPQNEGCTSKLEMPLESKCTSFPQALCVQWKNAYALCWLDCILSALVHSEELKNTVTGLCSKEESIFWRLLTKYNQANTLLYTSQLSGVKDGDCKKLTSEIFAEIETCLNEVRDEIFISLQPQLRCTLGDMESPVFAFPLLLKLETHIEKLFLYSFSWDFECSQCGHQYQNRHMKSLVTFTNVIPEWHPLNAAHFGPCNNCNSKSQIRKMVLEKVSPIFMLHFVEGLPQNDLQHYAFHFEGCLYQITSVIQYRANNHFITWILDADGSWLECDDLKGPCSERHKKFEVPASEIHIVIWERKISQVTDKEAACLPLKKTNDQHALSNEKPVSLTSCSVGDAASAETASVTHPKDISVAPRTLSQDTAVTHGDHLLSGPKGLVDNILPLTLEETIQKTASVSQLNSEAFLLENKPVAENTGILKTNTLLSQESLMASSVSAPCNEKLIQDQFVDISFPSQVVNTNMQSVQLNTEDTVNTKSVNNTDATGLIQGVKSVEIEKDAQLKQFLTPKTEQLKPERVTSQVSNLKKKETTADSQTTTSKSLQNQSLKENQKKPFVGSWVKGLISRGASFMPLCVSAHNRNTITDLQPSVKGVNNFGGFKTKGINQKASHVSKKARKSASKPPPISKPPAGPPSSNGTAAHPHAHAASEVLEKSGSTSCGAQLNHSSYGNGISSANHEDLVEGQIHKLRLKLRKKLKAEKKKLAALMSSPQSRTVRSENLEQVPQDGSPNDCESIEDLLNELPYPIDIASESACTTVPGVSLYSSQTHEEILAELLSPTPVSTELSENGEGDFRYLGMGDSHIPPPVPSEFNDVSQNTHLRQDHNYCSPTKKNPCEVQPDSLTNNACVRTLNLESPMKTDIFDEFFSSSALNALANDTLDLPHFDEYLFENY", "length": 1092 }, "evidence": [ { "id": "E1BB54", "url": "https://omabrowser.org/oma/group/E1BB54/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "deSUMOylase activity", "id": "GO:0016929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016929", "evidence": [ { "database": "UniProtKB", "id": "E1BB54", "url": "https://www.uniprot.org/uniprotkb/E1BB54" } ], "pmid": "" }, { "name": "SUMO binding", "id": "GO:0032183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032183", "evidence": [ { "database": "UniProtKB", "id": "E1BB54", "url": "https://www.uniprot.org/uniprotkb/E1BB54" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "snRNA transcription", "id": "GO:0009301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009301", "evidence": [ { "database": "UniProtKB", "id": "E1BB54", "url": "https://www.uniprot.org/uniprotkb/E1BB54" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "E1BB54", "url": "https://www.uniprot.org/uniprotkb/E1BB54" } ], "pmid": "" }, { "name": "Cajal body organization", "id": "GO:0030576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030576", "evidence": [ { "database": "UniProtKB", "id": "E1BB54", "url": "https://www.uniprot.org/uniprotkb/E1BB54" } ], "pmid": "" }, { "name": "protein desumoylation", "id": "GO:0016926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016926", "evidence": [ { "database": "UniProtKB", "id": "E1BB54", "url": "https://www.uniprot.org/uniprotkb/E1BB54" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "E1BB54", "url": "https://www.uniprot.org/uniprotkb/E1BB54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1036, "end_pos": 1038, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1079, "end_pos": 1081, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 671, "end_pos": 673, "annotation": "n_glycosylation_sequon" }, { "start_pos": 696, "end_pos": 698, "annotation": "n_glycosylation_sequon" }, { "start_pos": 914, "end_pos": 916, "annotation": "n_glycosylation_sequon" }, { "start_pos": 932, "end_pos": 934, "annotation": "n_glycosylation_sequon" }, { "start_pos": 953, "end_pos": 955, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "E1BB92", "url": "https://www.uniprot.org/uniprotkb/E1BB92" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BB92", "url": "https://www.uniprot.org/uniprotkb/E1BB92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BB92-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 115, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BB92-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BB92" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BB98-1", "uniprot_ac": "E1BB98", "uniprot_id": "E1BB98_BOVIN", "mass": { "chemical_mass": 46497.0, "monoisotopic_mass": 46497.0 }, "refseq": { "ac": "XP_059738649", "name": "protein ZNF365", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738649" }, "gene_names": [ { "name": "ZNF365", "type": "recommended", "evidence": [ { "id": "E1BB98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB98" } ] }, { "name": "ZNF365", "type": "synonym", "evidence": [ { "id": "XP_059738649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738649" } ] } ], "protein_names": [ { "name": "Zinc finger protein 365", "type": "synonym", "evidence": [ { "id": "E1BB98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB98/entry#names_and_taxonomy" } ] }, { "name": "protein ZNF365", "type": "synonym", "evidence": [ { "id": "XP_059738649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738649" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BB98", "url": "https://www.uniprot.org/uniprotkb/E1BB98" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF365", "url": "https://www.uniprot.org/uniprotkb/E1BB98", "locus": { "chromosome": "28", "start_pos": 18494490, "end_pos": 18469313, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010591", "url": "https://www.ensembl.org/id/ENSBTAG00000010591" } ] } } ], "crossref": [ { "id": "E1BB98", "url": "https://alphafold.ebi.ac.uk/entry/E1BB98", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010591", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010591", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "521207", "url": "https://www.ncbi.nlm.nih.gov/gene/521207", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521207", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521207", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNHADLK", "url": "https://omabrowser.org/oma/group/CNHADLK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BB98", "url": "https://www.orthodb.org/?gene=E1BB98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15739", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15739", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15739:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15739:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059738649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BB98", "url": "https://www.uniprot.org/uniprotkb/E1BB98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BB98-1", "url": "https://www.uniprot.org/uniprotkb/E1BB98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYQERTLLTKCSLFPSLKDTDLVTSSEPPKQGKLQSCGNIVKQKPSYVNLYSISHEHSKDRKPFEMVAERPVSYVQTYTTVDLRADSPDAPRASPGLPAPDTKAAFEAHVREKFSRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAALRQRLTESEEELLRKEEEVVTFNHFLETAAEKEVQGKARLQDFIENLLHRVELAEKQLEYYHSRQGAGPCGDPREHALTDISSNRKPKYLSRGHLHSVYNHPDLKTHFHPKGRMKKAKDDRASVQPAKSLHEQTESPRELCRPAKKGEPLGFGRKGNIRPKMAKKKPTAIVNII", "length": 405, "header": "tr|E1BB98-1|E1BB98_BOVIN Isoform 1 of Zinc finger protein 365 OS=Bos taurus OX=9913 GN=ZNF365 PE=4 SV=1 CANONICAL=E1BB98-1" }, "isoforms": [ { "isoform_ac": "E1BB98-1", "url": "https://www.uniprot.org/uniprotkb/E1BB98/entry#E1BB98-1", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYQERTLLTKCSLFPSLKDTDLVTSSEPPKQGKLQSCGNIVKQKPSYVNLYSISHEHSKDRKPFEMVAERPVSYVQTYTTVDLRADSPDAPRASPGLPAPDTKAAFEAHVREKFSRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAALRQRLTESEEELLRKEEEVVTFNHFLETAAEKEVQGKARLQDFIENLLHRVELAEKQLEYYHSRQGAGPCGDPREHALTDISSNRKPKYLSRGHLHSVYNHPDLKTHFHPKGRMKKAKDDRASVQPAKSLHEQTESPRELCRPAKKGEPLGFGRKGNIRPKMAKKKPTAIVNII", "length": 405, "header": "tr|E1BB98-1|E1BB98_BOVIN Isoform 1 of Zinc finger protein 365 OS=Bos taurus OX=9913 GN=ZNF365 PE=4 SV=1 CANONICAL=E1BB98-1" }, "locus": { "chromosome": "28", "start_pos": 18494483, "end_pos": 18471343, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014000.6", "url": "https://www.ensembl.org/id/ENSBTAT00000014000.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014000.3", "url": "https://www.ensembl.org/id/ENSBTAP00000014000.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:521207", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521207", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TUP2-1", "protein_name": "Zinc finger protein 365", "gene_name": "ZNF365", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYQERTLLTKCSIFPSIKDTDLVTSSEPLKQGKLQSCGNIVKQRPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAVDLRADSLDGPRSSPGLPTSDTKAAFEAHVREKFNQMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAALRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLHRVELAEKQLEYYHGQHAAGLHWDTSEHGLTDIASNRKPKCLSRGHPHSMCNHPDLKIHFHPKGRSYLKKAKDDRASMQPAKCMHEQAESPRDLCRPAKKGEPLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "E1BB98", "url": "https://omabrowser.org/oma/group/E1BB98/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Y3Z0-1", "protein_name": "Zinc finger protein 365", "gene_name": "ZNF365", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQQDAAEQSGFPWQDALGDASLRLPFRCPRCGERSRFRSLSALRAHLEYGHGYEERSVPPKGGPPSPRKGAGPASPPEPCGPGSATRYAPCAGFCDASSGSAEGRRALEAERGPVCCLAGYAPAGSPGSRLSSPVLPAADSKASFEAHVREKFNRMVEAVDKTIEKRIDKLTKELAQKTAELLEVRAAFVQLSQKKQEVQRRERALSRQVDVAVEMIAALKQRLTESEEELHRKEEEVVTFNHFLEEAAEKEVRGKARLQHFIENLLQRVDLAERQLEYYQNQQIACNHTGGSDHVVSQQSSFINCHPPLRGKCSASNFTDISSNKKPRCLSRGSQHTSYNIPDTKPHSFQKGRGLLKKAKEEKTSLQPVRCFYEPVDCPREIWRAQKKGEPVCSARKLSAKSKMGKKTKQL", "length": 412 }, "evidence": [ { "id": "E1BB98", "url": "https://omabrowser.org/oma/group/E1BB98/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5PQS2-1", "protein_name": "Protein ZNF365", "gene_name": "Znf365", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQQTTFEESRYRWQDSLENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLLPSLKDTDLLRSSELPKQGKLLRGHAKVTKQKPSYVNLYSISHGHSKDPKPFEMVAERPVSYVQTYTAVDIRADSLDAPRSSSGLPTQDTKAAFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALHKQVDVAVEMIAVLKQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFSHDTSEHMLTDISSSRKSRCLSRGHQHSVCNHPELKAHFHLKGRSYLKKAKDERAGMQPAKAIHEQAESPREFFRPAKKGEHLGLSRKGNFRPKMAKKKPTAIVNII", "length": 408 }, "evidence": [ { "id": "E1BB98", "url": "https://omabrowser.org/oma/group/E1BB98/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "E1BB98", "url": "https://omabrowser.org/oma/group/E1BB98/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BG89-1", "protein_name": "Protein ZNF365", "gene_name": "Znf365", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQQTTFEESRYHWQDSLENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLLPSLKDTELLRSSELPKQGKVLRGHAKVTKQKSSYVNLYSISHGHSKDTKPFEMVAERPVSYVQTYTAVDIRADSLDAPCASPGLPTQDTKAAFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFAQLTQKKQEVQRRERALNKQVDVAVEMIAVLKQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFSCDTSEHMLTDIPSNRKPRCLSRGHQHSVCNHPEMRAHFHLKGRSYLKKAKDERAGMQPAKAIHEPAESPREFFRPAKKGEHLGLSRKGNFRPKMAKKKPTAIVNII", "length": 408 }, "evidence": [ { "id": "E1BB98", "url": "https://omabrowser.org/oma/group/E1BB98/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BB98", "url": "https://www.uniprot.org/uniprotkb/E1BB98" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of oligodendrocyte differentiation", "id": "GO:0048714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048714", "evidence": [ { "database": "UniProtKB", "id": "E1BB98", "url": "https://www.uniprot.org/uniprotkb/E1BB98" } ], "pmid": "" }, { "name": "dendrite arborization", "id": "GO:0140059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140059", "evidence": [ { "database": "UniProtKB", "id": "E1BB98", "url": "https://www.uniprot.org/uniprotkb/E1BB98" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "E1BB98", "url": "https://www.uniprot.org/uniprotkb/E1BB98" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "E1BB98", "url": "https://www.uniprot.org/uniprotkb/E1BB98" } ], "pmid": "" }, { "name": 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"https://www.uniprot.org/uniprotkb/E1BB98" } ], "pmid": "" }, { "name": "regulation of double-strand break repair via homologous recombination", "id": "GO:0010569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010569", "evidence": [ { "database": "UniProtKB", "id": "E1BB98", "url": "https://www.uniprot.org/uniprotkb/E1BB98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BB98-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 405, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BB98-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BB98" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BB98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB98" }, { 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UDP-glucuronosyltransferase OS=Bos taurus OX=9913 GN=LOC100138004 PE=1 SV=3 CANONICAL=E1BBB3-1" }, "isoforms": [ { "isoform_ac": "E1BBB3-1", "url": "https://www.uniprot.org/uniprotkb/E1BBB3/entry#E1BBB3-1", "sequence": { "sequence": "MNMMAVKRLLLLLLLQLTCYFSSGSCGKVLVWPVEYSHWMNMKIILDELVMRGHEVTVLTSSASILIDPNKPSAIKFENFSVSLTKDDFEDALKNFVGNWTDLTNSFWTFPLLLQSLFDEYSDLTLKICKELISNKKLMTKLHESRFDVVLADTVGPCGELLAEIFKVPLVYSVRFTPGYSIERKSGKLPYSPSYVPVILSELSDHMTFMERVKNMIYVLYFDFYFQMLNEKKWDQFYSEVLGRPTTLLETMGKAEFWLFRSYWDFEYPCPLLPNVEFIGGLHCKPAKPLPKEMEEFVQSSGENGIVVFTLGSMVTNVTEERANMIASALAQIPQKVLWRYDGKKPDTLGPNTRLYKWVPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGLPLFAEQPDNINRVKAKGAAVRLNLETMSKTDFLNALKQVINNPSYKRNAMWLSTIQRDQPMKPLDRAVFWIEFVMRHKGAKYLRPAAHKLTWFQYHSLDVIGFLLACVATAVFVITKCFLFCCRKFAETGKKRKRE", "length": 531, "header": "tr|E1BBB3-1|E1BBB3_BOVIN Isoform 1 of UDP-glucuronosyltransferase OS=Bos taurus OX=9913 GN=LOC100138004 PE=1 SV=3 CANONICAL=E1BBB3-1" }, "locus": { "chromosome": "6", "start_pos": 84210644, "end_pos": 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"evidence": [ { "database": "UniProtKB", "id": "E1BBB3", "url": "https://www.uniprot.org/uniprotkb/E1BBB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "E1BBB3", "url": "https://www.uniprot.org/uniprotkb/E1BBB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21032", "name": "", "equation": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9T3U6-1", "G3N150-1", "F1MFF6-1", "F1MRL5-1", "E1BBB3-1", "E1BJU8-1", "A0AAA9S6P8-1", "A0A3Q1M7T0-1", "A0A3Q1MKS1-1", "A0A3Q1LYU5-1", "A0AAA9TS57-1" ], "evidence": [ { "id": "21032", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21032" } ] }, { "id": "R-BTA-158546", "name": "UGTs glucuronate APAP to APAP-GlcA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-158601" ], "output_participant_list": [ "R-ALL-158604" ], "enzyme_list": [ "E1BJU8-1", "A0A3Q1LYU5-1", "F1MFF6-1", "E1BBB3-1" ], "evidence": [ { "id": "R-BTA-158546", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-158546" } ] }, { "id": "R-BTA-9758661", "name": "UGT2B7,2B17,1A3 glucuronidates PRED metabolites", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BJU8-1", "A0A3Q1LYU5-1", "F1MFF6-1", "E1BBB3-1" ], "evidence": [ { "id": "R-BTA-9758661", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9758661" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-158601", "participant_name": "UDP-GlcA [cytosol]", "crossref": [ { "id": "58052", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215691", "database": "ZINC", "url": "" }, { "id": "C00167", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-158604", "participant_name": "APAP-GlcA [endoplasmic reticulum lumen]", "crossref": [ { "id": "ZINC000005197198", "database": "ZINC", "url": "" }, { "id": "132962", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LYU5", "gene_name": "LOC100138908", "activity": [ { 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Plays a role in RNA processing and termination.", "evidence": [ { "database": "UniProtKB", "id": "E1BBD9", "url": "https://www.uniprot.org/uniprotkb/E1BBD9#function" }, { "database": "UniProtKB", "id": "RU369031", "url": "https://www.uniprot.org/uniprotkb/RU369031#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BBD9", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC112445820", "url": "https://www.uniprot.org/uniprotkb/E1BBD9", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000019221", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019221", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HNILNKR", "url": "https://omabrowser.org/oma/group/HNILNKR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR20383", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BBD9", "url": "https://www.uniprot.org/uniprotkb/E1BBD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBD9-1", "url": "https://www.uniprot.org/uniprotkb/E1BBD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195, "header": "tr|E1BBD9-1|E1BBD9_BOVIN Isoform 1 of RNA polymerase II subunit A C-terminal domain phosphatase SSU72 OS=Bos taurus OX=9913 GN=LOC112445820 PE=3 SV=3 CANONICAL=E1BBD9-1" }, "isoforms": [ { "isoform_ac": "E1BBD9-1", "url": "https://www.uniprot.org/uniprotkb/E1BBD9/entry#E1BBD9-1", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195, "header": "tr|E1BBD9-1|E1BBD9_BOVIN Isoform 1 of RNA polymerase II subunit A C-terminal domain phosphatase SSU72 OS=Bos taurus OX=9913 GN=LOC112445820 PE=3 SV=3 CANONICAL=E1BBD9-1" }, "locus": { "chromosome": "NKLS02002208.1", "start_pos": 6043725, "end_pos": 6043057, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073504.1", "url": "https://www.ensembl.org/id/ENSBTAT00000073504.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056884.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056884.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "E1BBD9", "url": "https://omabrowser.org/oma/group/E1BBD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "E1BBD9", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "termination of RNA polymerase II transcription", "id": "GO:0006369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006369", "evidence": [ { "database": "UniProtKB", "id": "E1BBD9", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "E1BBD9", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA polymerase II CTD heptapeptide repeat phosphatase activity", "id": "GO:0008420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008420", "evidence": [ { "database": "UniProtKB", "id": "E1BBD9", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEW5-1", "A0AAA9TV14-1", "A0AAA9S745-1", "A0A3Q1MV48-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "F1MBQ1-1", "A0AAA9RTM1-1", "A0AAF6YJP2-1", "P48452-1", "F1MI99-1", "G3N3B3-1", "O62830-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "A6H772-1", "O62829-1", "P61287-1", "A0AAA9U0H6-1", "Q3ZBF9-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q0P594-1", "Q1RMV9-1", "Q2KJ36-1", "Q2PC20-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0A3Q1N224-1", "E1BMD4-1", "A0AAF6DLF7-1", "F1N580-1", "F1MQM7-1", "F1MW60-1", "F1N719-1", "E1BF95-1", "E1BIE7-1", "F1MEZ2-1", "F1MM08-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLF7-1", "F1MI92-1", "A0A3Q1MV48-1", "E1BEW5-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "A0ABI0P1A3-1", "F1MBQ1-1", "A0AAA9RTM1-1", "G3N3B3-1", "A0AAF6YJP2-1", "P48452-1", "O62829-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "Q0P594-1", "A6H772-1", "O62830-1", "P61287-1", "A0AAA9U0H6-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q1RMV9-1", "Q2KJ36-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "E1BIZ2-1", "F1MI99-1", "F1MP34-1", "F1MEZ2-1", "F1MQM7-1", "F1MM08-1", "F1N719-1", "A0AAA9T455-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0AAA9TV14-1", "A0AAA9S745-1", "F1N580-1", "E1BMD4-1", "E1BF95-1", "E1BIE7-1", "A0A3Q1N224-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1MLC5", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] } ] }, { "uniprot_ac": "A0A3Q1MV48", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] } ] }, { "uniprot_ac": "A0A3Q1MZU1", "gene_name": "CTDSPL2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] } ] }, { "uniprot_ac": "A0A3Q1N224", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] } ] }, { "uniprot_ac": "A0A3Q1N5B2", "gene_name": "CDC14B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S454", "gene_name": "LOC112441581", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S454" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S454" } ] } ] }, { "uniprot_ac": "A0AAA9S745", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] } ] }, { "uniprot_ac": "A0AAA9SCR0", "gene_name": "LOC112441582", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCR0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCR0" } ] } ] }, { "uniprot_ac": "A0AAA9SWY4", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] } ] }, { "uniprot_ac": "A0AAA9T455", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] } ] }, { "uniprot_ac": "A0AAA9TD32", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD32" } ] } ] }, { "uniprot_ac": "A0AAA9TT76", "gene_name": "PPP3CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT76" } ] } ] }, { "uniprot_ac": "A0AAA9TV14", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TV14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TV14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YJP2", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] } ] }, { "uniprot_ac": "A0ABI0P1A3", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0ABI0P1A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0ABI0P1A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ] } ] }, { "uniprot_ac": "A5PJZ2", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A5PJZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A5PJZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJZ2" } ] } ] }, { "uniprot_ac": "A6H772", "gene_name": "PPP4C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A6H772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H772" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A6H772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H772" } ] } ] }, { "uniprot_ac": "E1B9Y5", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] } ] }, { "uniprot_ac": "E1BAB2", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] } ] }, { "uniprot_ac": "E1BBD9", "gene_name": "LOC112445820", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] } ] }, { "uniprot_ac": "E1BEW5", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] } ] }, { "uniprot_ac": "E1BF95", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] } ] }, { "uniprot_ac": "E1BIE7", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] } ] }, { "uniprot_ac": "E1BIZ2", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] } ] }, { "uniprot_ac": "E1BMD4", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] } ] }, { "uniprot_ac": "F1MBQ1", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MI92", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MW60", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1N580", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] } ] }, { "uniprot_ac": "F1N719", "gene_name": "PPP5C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] } ] }, { "uniprot_ac": "F6RRD7", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] } ] }, { "uniprot_ac": "G3N3B3", "gene_name": "PPM1N", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] } ] }, { "uniprot_ac": "O62829", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"sequence": "MSSREPLSLAGPLAAYNLELVVLSGYMFYEFMATSLLANYSYLCQPVDYSQNELWMRMASVCWWCFFSKVLELLDTVFFILRKKPEQITFLHLYHHGTVLFNWWAGVKYVPGGQAFVGMLNALVHVFTYLYYGLASLGPRLHPFLWWKRHLTILQLGQFVAIAACSSYNLFAECPFPDSFNVAVLLYSLSLLALFLNSYQQTYLRNKQKKLA", "length": 212, "header": "tr|E1BBK7-1|E1BBK7_BOVIN Isoform 1 of Elongation of very long chain fatty acids protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BBK7-1" }, "locus": { "chromosome": "5", "start_pos": 105173672, "end_pos": 105167857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000037720.5", "url": "https://www.ensembl.org/id/ENSBTAT00000037720.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000037544.4", "url": "https://www.ensembl.org/id/ENSBTAP00000037544.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BBK7", "url": "https://www.uniprot.org/uniprotkb/E1BBK7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "E1BBK7", "url": "https://www.uniprot.org/uniprotkb/E1BBK7" } ], "pmid": "" }, { "name": "fatty acid elongation, monounsaturated fatty acid", "id": "GO:0034625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034625", "evidence": [ { "database": "UniProtKB", "id": "E1BBK7", "url": "https://www.uniprot.org/uniprotkb/E1BBK7" } ], "pmid": "" }, { "name": "fatty acid elongation, polyunsaturated fatty acid", "id": "GO:0034626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034626", "evidence": [ { "database": "UniProtKB", "id": "E1BBK7", "url": "https://www.uniprot.org/uniprotkb/E1BBK7" } ], "pmid": "" }, { "name": "fatty acid elongation, saturated fatty acid", "id": "GO:0019367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019367", "evidence": [ { "database": "UniProtKB", "id": "E1BBK7", "url": "https://www.uniprot.org/uniprotkb/E1BBK7" } ], "pmid": "" }, { "name": "very long-chain fatty acid biosynthetic process", "id": "GO:0042761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042761", "evidence": [ { "database": "UniProtKB", "id": "E1BBK7", "url": "https://www.uniprot.org/uniprotkb/E1BBK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "fatty acid elongase activity", "id": "GO:0009922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009922", "evidence": [ { "database": "UniProtKB", "id": "E1BBK7", "url": "https://www.uniprot.org/uniprotkb/E1BBK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "32727", "name": "", "equation": "a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BBK7-1", "F1MMX8-1", "A0JNC4-1", "Q2KJD9-1", "A0AAF6DMC9-1", "E1BBR7-1" ], "evidence": [ { "id": "32727", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32727" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAF6DMC9", "gene_name": "ELOVL6", "activity": [ { "ec_number": "2.3.1.199", "activity": "a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA.", "evidence": [ { "id": "A0AAF6DMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMC9" } ] }, { "ec_number": "2.3.1.199", "activity": "", "evidence": [ { "id": "A0AAF6DMC9", 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"https://www.uniprot.org/uniprotkb/E1BBK7" } ] } ] }, { "uniprot_ac": "E1BBR7", "gene_name": "ELOVL3", "activity": [ { "ec_number": "2.3.1.199", "activity": "a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA.", "evidence": [ { "id": "E1BBR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBR7" } ] }, { "ec_number": "2.3.1.199", "activity": "", "evidence": [ { "id": "E1BBR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBR7" } ] } ] }, { "uniprot_ac": "F1MMX8", "gene_name": "MED8", "activity": [ { "ec_number": "2.3.1.199", "activity": "a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA.", "evidence": [ { "id": "F1MMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMX8" } ] }, { "ec_number": "2.3.1.199", "activity": "", "evidence": [ { "id": "F1MMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMX8" } ] } ] }, { "uniprot_ac": "Q2KJD9", "gene_name": "ELOVL5", "activity": [ { "ec_number": "2.3.1.199", "activity": "a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA.", "evidence": [ { "id": "Q2KJD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJD9" } ] }, { "ec_number": "2.3.1.199", "activity": "", "evidence": [ { "id": "Q2KJD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJD9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BBK7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 212, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BBK7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BBK7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.199", "ec_name": "a very-long-chain acyl-CoA + 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBL2-1", "url": "https://www.uniprot.org/uniprotkb/E1BBL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGIRGFVPFCPWNWCLLLATLQCCGASSELNRSTDSSARRELNVRYAAASSQPAETISVFTLDYDYVQIPYEVTLWILLASLAKIGFHLNRRLPGLMPESCLLILVGALVGAVIFGTDHKSPPVMDSSIYFLYLLPPIVLESGYFMPTRPFFENLGSILWWAGLGALLNAFGIGLSLYLICQVPAFGLGDINLLQNLLFGSLISAVDPVAVLAVFEEACVNEQLYMMIFGEALLNDGISVVLYNILIAFTKMHKFEDIEPVDILAGCARFVIVGCGGAFFGVIFGFISAFITRFTQNISAIEPLIVFMFSYLSYLVAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSSVSETLIFIFMGVSTIGKNHEWNWAFICFTLVFCQIWRAISVFVLFYVSNQFRTFPFSIKDQCVIFYSGVRGAGSFSLAFLLPLSLFPRKKLFVTATLVVIYFTVFIQGITVGPLVRYLDVRKTNKKESINEELHTRLMDHLKAGIEDVCGQWSHYQVRDKFKKFDHKYLRKILIRKNLPKSSLVSLYKKLEMKQAIEMVESGVLSSTAFSTPRRVQKTQETKRLSPEDVESMRDILTRNMYQVRQRTLSYNKYNLQPQTSEKQAKEILIRRRNTFRESVKKGHSLPWGKPAGTKNIRYLSFPYSKPLPAGRDMKVAEFTDHDGSDSELPPITFNTHSPTGTIQERRWTPEVIPMKRLHGAGTPLHFGYRRNAGREEHLGRGGRAILRPKPLFHAVDEEFESEEESKEETPAFGSLLSSELRPGGDCNVSHSPLLQRK", "length": 797, "header": "tr|E1BBL2-1|E1BBL2_BOVIN Isoform 1 of Sodium/hydrogen exchanger OS=Bos taurus OX=9913 GN=SLC9A4 PE=3 SV=3 CANONICAL=E1BBL2-1" }, "isoforms": [ { "isoform_ac": "E1BBL2-1", "url": "https://www.uniprot.org/uniprotkb/E1BBL2/entry#E1BBL2-1", "sequence": { "sequence": "MGIRGFVPFCPWNWCLLLATLQCCGASSELNRSTDSSARRELNVRYAAASSQPAETISVFTLDYDYVQIPYEVTLWILLASLAKIGFHLNRRLPGLMPESCLLILVGALVGAVIFGTDHKSPPVMDSSIYFLYLLPPIVLESGYFMPTRPFFENLGSILWWAGLGALLNAFGIGLSLYLICQVPAFGLGDINLLQNLLFGSLISAVDPVAVLAVFEEACVNEQLYMMIFGEALLNDGISVVLYNILIAFTKMHKFEDIEPVDILAGCARFVIVGCGGAFFGVIFGFISAFITRFTQNISAIEPLIVFMFSYLSYLVAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSSVSETLIFIFMGVSTIGKNHEWNWAFICFTLVFCQIWRAISVFVLFYVSNQFRTFPFSIKDQCVIFYSGVRGAGSFSLAFLLPLSLFPRKKLFVTATLVVIYFTVFIQGITVGPLVRYLDVRKTNKKESINEELHTRLMDHLKAGIEDVCGQWSHYQVRDKFKKFDHKYLRKILIRKNLPKSSLVSLYKKLEMKQAIEMVESGVLSSTAFSTPRRVQKTQETKRLSPEDVESMRDILTRNMYQVRQRTLSYNKYNLQPQTSEKQAKEILIRRRNTFRESVKKGHSLPWGKPAGTKNIRYLSFPYSKPLPAGRDMKVAEFTDHDGSDSELPPITFNTHSPTGTIQERRWTPEVIPMKRLHGAGTPLHFGYRRNAGREEHLGRGGRAILRPKPLFHAVDEEFESEEESKEETPAFGSLLSSELRPGGDCNVSHSPLLQRK", "length": 797, "header": "tr|E1BBL2-1|E1BBL2_BOVIN Isoform 1 of Sodium/hydrogen exchanger OS=Bos taurus OX=9913 GN=SLC9A4 PE=3 SV=3 CANONICAL=E1BBL2-1" }, "locus": { "chromosome": "11", "start_pos": 7296373, "end_pos": 7241773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033196.7", "url": "https://www.ensembl.org/id/ENSBTAT00000033196.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033117.5", "url": "https://www.ensembl.org/id/ENSBTAP00000033117.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:536970", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536970", "resource": "KEGG Pathway" }, { "id": "R-BTA-425986", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-425986", "resource": "Reactome", "description": "Sodium/Proton exchangers" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M1L0-1", "protein_name": "Sodium/hydrogen exchanger", "gene_name": "Slc9a4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLAIHMAFSSWNWLLWLMVLACSEASSYVNESSNSTAQQAPDARFAASSSDPDERISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHKLPHLMPESCLLLIVGALVGGIIFGTHHKSPPVMDSSIYFLYLLPPIVLESGYFMPTRPFFENIGSILWWAGLGALINAFGIGLSLYFICQIKAFGLGDINLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGISVVLYNILIAFTKMHKFEDIEPVDILAGCARFVIVGCGGVFFGIIFGFISAFITRFTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSSVSETLIFIFMGVSTIGKNHEWNWAFICFTLVFCQIWRAISVFTLFYVSNQFRTFPFSIKDQFIIFYSGVRGAGSFSLAFLLPLSLFPRKKLFVTATLVVTYFTVFFQGITIGPLVRYLDVRKTNKKESINEELHIRLMDHLKAGIEDVCGQWSHYQVRDKFKKFDHRYLRKILIRRNLPKSSIVSLYKKLEMKQAIEMVETGILTSAAFSTLYQPERIQGTKRLSPEDVESMRDILTRNMYQVRQRTLSYNKYSLKPQTSEKQAKEILIRRQNTLRESMRKGQSLPWGKPTGTKNFRYLSFPYSNPQSARREARAAEPTDDDGIHPGFQPLMFSAHSRAGSLQERRQTQAMIPMKSLHRGEKALSFSYRSNTSWEDHAGWGRRDAIRPKPLFYAVDEEYESGEQTEEEISATGTRWIAEHRRSREHYKSHSPLLHRK", "length": 797 }, "evidence": [ { "id": "E1BBL2", "url": "https://omabrowser.org/oma/group/E1BBL2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P26434-1", "protein_name": "Sodium/hydrogen exchanger 4", "gene_name": "Slc9a4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPAMLRAFSSWKWLLLLMVLTCLEASSYVNESSSPTGQQTPDARFAASSSDPDERISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPHLMPESCLLIIVGALVGSIIFGTHHKSPPVMDSSIYFLYLLPPIVLESGYFMPTRPFFENIGSILWWAGLGALINAFGIGLSLYFICQIKAFGLGDINLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGISVVLYNILIAFTKMHKFEDIEAVDILAGCARFVIVGCGGVFFGIIFGFISAFITRFTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFVCFTLAFCQIWRAISVFTLFYVSNQFRTFPFSIKDQLIIFYSGVRGAGSFSLAFLLPLTLFPRKKLFVTATLVVTYFTVFFQGITIGPLVRYLDVRKTNKKESINEELHIRLMDHLKAGIEDVCGQWSHYQVRDKFKKFDHRYLRKILIRRNQPKSSIVSLYKKLEMKQAIEMAETGLLSSVASPTPYQSERIQGIKRLSPEDVESMRDILTRNMYQVRQRTLSYNKYNLKPQTSEKQAKEILIRRQNTLRESLRKGQSLPWVKPAGTKNFRYLSFPYSNPQPARRGARAAESTGNPCCWLLHFLLCRAMVEKIWGPGGQETQPRLLCRNLN", "length": 717 }, "evidence": [ { "id": "E1BBL2", "url": "https://omabrowser.org/oma/group/E1BBL2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AI14-1", "protein_name": "Sodium/hydrogen exchanger 4", "gene_name": "SLC9A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALQMFVTYSPWNCLLLLVALECSEASSDLNESANSTAQYASNAWFAAASSEPEEGISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVGGIIFGTDHKSPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLYLICQVKAFGLGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPFSIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVRYLDVKKTNKKESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKILIRKNLPKSSIVSLYKKLEMKQAIEMVETGILSSTAFSIPHQAQRIQGIKRLSPEDVESIRDILTSNMYQVRQRTLSYNKYNLKPQTSEKQAKEILIRRQNTLRESMRKGHSLPWGKPAGTKNIRYLSYPYGNPQSAGRDTRAAGFSDDDSSDPGSPSITFSACSRIGSLQKQEAQEIIPMKSLHRGRKAFSFGYQRNTSQEEYLGGVRRVALRPKPLFHAVDEEGESGGESEGKASLVEVRSRWTADHGHGRDHHRSHSPLLQKK", "length": 798 }, "evidence": [ { "id": "E1BBL2", "url": "https://omabrowser.org/oma/group/E1BBL2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BUE1-1", "protein_name": "Sodium/hydrogen exchanger 4", "gene_name": "Slc9a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPAMFMAFRLWNWLLLLAVLTRSEATSYVNESSNPTAQQAPDARFAASSSDPDEGISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPHLMPESCLLIIVGALVGGIIFGTHHKSPPVMDSSIYFLYLLPPIVLESGYFMPTRPFFENIGSILWWAGLGALINAFGIGLSLYFICQIKAFGLGDINLLHNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGISVVLYNILIAFTKMHKFEDIEAVDILAGCARFVIVGCGGVFFGIIFGFISAFITRFTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSSVSETLIFIFMGVSTIGKNHEWNWAFICFTLLFCQIWRAISVFTLFYVSNQFRTFPFSIKDQFIIFYSGVRGAGSFSLAFLLPLSLFPRKKLFVTATLVVTYFTVFFQGITIGPLVRYLDVRKTNKKESINEELHSRLMDHLKAGIEDVCGQWSHYQVRDKFKKFDHRYLRKILIRRNLPKSSIVSLYKKLEMKQAIEMVETGILSSVASPTPYQSERIQGIKRLSPEDVESMRDILTRSMYQVRQRTLSYNKYNLKPQTSEKQAKEILIRRQNTLRESMRKGQSLPWGKPAGTKNFRYLSFPYSNPQAARREARAAEPTDDDGTDSGFQPLMFSIHSRAGSLQERRQTQAVIPMKRLQRGEKALSFSYRSNTSWEDQAGWRRMDVLRPKPLFYAVAEEYDSGEQTEEETSAILSRWTAEHRHSTEHHKSHSPLLHRK", "length": 797 }, "evidence": [ { "id": "E1BBL2", "url": "https://omabrowser.org/oma/group/E1BBL2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "E1BBL2", "url": "https://www.uniprot.org/uniprotkb/E1BBL2" } ], "pmid": "" }, { "name": "potassium:proton antiporter activity", "id": "GO:0015386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", "evidence": [ { "database": "UniProtKB", "id": "E1BBL2", "url": "https://www.uniprot.org/uniprotkb/E1BBL2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "transepithelial ammonium transport", "id": "GO:0070634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070634", "evidence": [ { "database": "UniProtKB", "id": "E1BBL2", "url": "https://www.uniprot.org/uniprotkb/E1BBL2" } ], "pmid": "" }, { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "E1BBL2", "url": "https://www.uniprot.org/uniprotkb/E1BBL2" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "E1BBL2", "url": "https://www.uniprot.org/uniprotkb/E1BBL2" } ], "pmid": "" }, { "name": "sodium ion import across plasma membrane", "id": "GO:0098719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098719", "evidence": [ { "database": "UniProtKB", "id": "E1BBL2", "url": "https://www.uniprot.org/uniprotkb/E1BBL2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BBL2", "url": "https://www.uniprot.org/uniprotkb/E1BBL2" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "E1BBL2", "url": "https://www.uniprot.org/uniprotkb/E1BBL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 787, "end_pos": 789, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BBL2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 797, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BBL2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BBL2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BBL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBL2" }, { "id": "PF00999", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00999" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cation/H+ exchanger transmembrane", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 476, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BBL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBL2" }, { "id": "PF16644", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16644" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sodium/hydrogen exchanger regulatory region", "eco_id": "ECO_0000259", "start_pos": 567, "end_pos": 672, "start_aa": "Thr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 297, "end_pos": 299 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 787, "end_pos": 789 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BBM5-1", "uniprot_ac": "E1BBM5", "uniprot_id": "E1BBM5_BOVIN", "mass": { "chemical_mass": 38102.0, "monoisotopic_mass": 38102.0 }, "refseq": { "ac": "NP_001069873", "name": "E3 ubiquitin-protein ligase RNF167", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069873" }, "gene_names": [ { "name": "RNF167", "type": "recommended", "evidence": [ { "id": "E1BBM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" } ] }, { "name": "RNF167", "type": "synonym", "evidence": [ { "id": "NP_001069873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069873" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF167", "type": "recommended", "evidence": [ { "id": "E1BBM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM5/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "E1BBM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM5/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase RNF167", "type": "synonym", "evidence": [ { "id": "NP_001069873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069873" } ] }, { "name": "RING finger protein 167", "type": "synonym", "evidence": [ { "id": "E1BBM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BBM5", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RNF167", "url": "https://www.uniprot.org/uniprotkb/E1BBM5", "locus": { "chromosome": "19", "start_pos": 26450761, "end_pos": 26455153, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004913", "url": "https://www.ensembl.org/id/ENSBTAG00000004913" } ] } } ], "crossref": [ { "id": "E1BBM5", "url": "https://alphafold.ebi.ac.uk/entry/E1BBM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004913", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004913", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02123", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02123", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16797", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16797", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616030", "url": "https://www.ncbi.nlm.nih.gov/gene/616030", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616030", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616030", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PSYDANT", "url": "https://omabrowser.org/oma/group/PSYDANT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BBM5", "url": "https://www.orthodb.org/?gene=E1BBM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45931", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45931", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45931:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45931:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069873", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069873", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BBM5", "url": "https://www.uniprot.org/uniprotkb/E1BBM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBM5-1", "url": "https://www.uniprot.org/uniprotkb/E1BBM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHPAAFPLPVVVVTVLWGAAPSRGLIRAISDHNASMDFADLPALFGAALSQEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNSFPLGYYLIPFTGIVGLLVLAMGAVMIVRCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDDEQEEESQGQEGDEEGEPRDQPASERTPLLGSSPTPPSSFGSIAPAPLVFPGSSTDPSPSTSSAAILV", "length": 349, "header": "tr|E1BBM5-1|E1BBM5_BOVIN Isoform 1 of E3 ubiquitin-protein ligase RNF167 OS=Bos taurus OX=9913 GN=RNF167 PE=3 SV=3 CANONICAL=E1BBM5-1" }, "isoforms": [ { "isoform_ac": "E1BBM5-1", "url": "https://www.uniprot.org/uniprotkb/E1BBM5/entry#E1BBM5-1", "sequence": { "sequence": "MHPAAFPLPVVVVTVLWGAAPSRGLIRAISDHNASMDFADLPALFGAALSQEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNSFPLGYYLIPFTGIVGLLVLAMGAVMIVRCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDDEQEEESQGQEGDEEGEPRDQPASERTPLLGSSPTPPSSFGSIAPAPLVFPGSSTDPSPSTSSAAILV", "length": 349, "header": "tr|E1BBM5-1|E1BBM5_BOVIN Isoform 1 of E3 ubiquitin-protein ligase RNF167 OS=Bos taurus OX=9913 GN=RNF167 PE=3 SV=3 CANONICAL=E1BBM5-1" }, "locus": { "chromosome": "19", "start_pos": 26454571, "end_pos": 26450930, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006464.5", "url": "https://www.ensembl.org/id/ENSBTAT00000006464.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006464.5", "url": "https://www.ensembl.org/id/ENSBTAP00000006464.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 316, "start_aa": "Thr", "end_pos": 316, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr316", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:616030", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616030", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RFY0-1", "protein_name": "E3 ubiquitin-protein ligase RNF167", "gene_name": "RNF167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHPAAFPLPVVVATVLWGVAPSQGLIRAISDHNASMDFADLPALFGAALSQEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSQYLRALFVYEKGARVLLVPDNSFPLGYYLIPFTGIVGLLVLAMGAVMIVRCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDRLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEEQEEETQEQEGDEEGEPRDHPASERTPLLGSSPTLPTSFGSLAPAPLVFPGSSTDPSPSISSSAAVLV", "length": 350 }, "evidence": [ { "id": "E1BBM5", "url": "https://omabrowser.org/oma/group/E1BBM5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5XIL0-1", "protein_name": "E3 ubiquitin-protein ligase RNF167", "gene_name": "Rnf167", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHPAAFPLPVVVATVLWGAAPIRGLIRATSEHNASMDFADLPALFGATLSDEGLQGFLVEAHPENACSPIAPPPSAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSAEYLRALFVYEKGARVLLVPDNSFPLGYYLIPFTGIVGLLVLAMGTVLIVRCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDEYDVCAICLDEYEDGDKLRILPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEEQEEETQGQEEEGDEGEPRDQPASEWTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPSPSPSSAALA", "length": 349 }, "evidence": [ { "id": "E1BBM5", "url": "https://omabrowser.org/oma/group/E1BBM5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91XF4-1", "protein_name": "E3 ubiquitin-protein ligase RNF167", "gene_name": "Rnf167", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPAAFPLPVVVATVLWGAAPVRGLIRATSEHNASMDFADLPALFGATLSDEGLQGFLVEAHPENACGPIAPPPSAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSAEYLRALFVYEKGARVLLVPDNSFPLGYYLIPFTGIVGLLVLAMGTVLIVRCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDEYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEEQEEETQEQEEGDEGEPRDQPASEWTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPSPPSSAALA", "length": 347 }, "evidence": [ { "id": "E1BBM5", "url": "https://omabrowser.org/oma/group/E1BBM5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M622-1", "protein_name": "Receptor homology region, transmembrane domain- and RING domain-containing protein 1", "gene_name": "RMR1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRLVVSSCLLVAAPFLSSLLRVSLATVVLNSISASFADLPAKFDGSVTKNGICGALYVADPLDGCSPLLHAAASNWTQHRTTKFALIIRGECSFEDKLLNAQNSGFQAVIVYDNIDNEDLIVMKVNPQDITVDAVFVSNVAGEILRKYARGRDGECCLNPPDRGSAWTVLAISFFSLLLIVTFLLIAFFAPRHWTQWRGRHTRTIRLDAKLVHTLPCFTFTDSAHHKAGETCAICLEDYRFGESLRLLPCQHAFHLNCIDSWLTKWGTSCPVCKHDIRTETMSSEVHKRESPRTDTSTSRFAFAQSSQSR", "length": 310 }, "evidence": [ { "id": "E1BBM5", "url": "https://omabrowser.org/oma/group/E1BBM5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of intracellular signal transduction", "id": "GO:1902532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902532", "evidence": [ { "database": "UniProtKB", "id": "E1BBM5", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "E1BBM5", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" } ], "pmid": "" }, { "name": "negative regulation of cell cycle", "id": "GO:0045786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045786", "evidence": [ { "database": "UniProtKB", "id": "E1BBM5", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BBM5", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BBM5", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "E1BBM5", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "E1BBM5", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BBM5", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BBM5", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BBM5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 349, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BBM5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BBM5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BBM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM5" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 230, "end_pos": 272, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 316 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 33, "end_pos": 35 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.ncbi.nlm.nih.gov/protein/NP_001179234" } ] } ], "protein_names": [ { "name": "Homeobox protein", "type": "recommended", "evidence": [ { "id": "E1BBR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBR5/entry#names_and_taxonomy" } ] }, { "name": "pituitary homeobox 3", "type": "synonym", "evidence": [ { "id": "NP_001179234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179234" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BBR5", "url": "https://www.uniprot.org/uniprotkb/E1BBR5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PITX3", "url": "https://www.uniprot.org/uniprotkb/E1BBR5", "locus": { "chromosome": "26", "start_pos": 22873667, "end_pos": 22885575, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015702", "url": "https://www.ensembl.org/id/ENSBTAG00000015702" } ] } } ], "crossref": [ { "id": "E1BBR5", "url": "https://alphafold.ebi.ac.uk/entry/E1BBR5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015702", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015702", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512000", "url": "https://www.ncbi.nlm.nih.gov/gene/512000", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003654", "database": "InterPro", "categories": [ "Protein 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"MEFGLLSEAEARSPALSLSDAGTPHPPLPEHGCKGQEHSDSEKASVSLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGGFAAPLGGLVPPYEEVYPGYSYGNWPPKALGPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSISASMVPSGATAPGTVPGHGALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPTVPGPPPAANLSPCQYAVERPV", "length": 302, "header": "tr|E1BBR5-1|E1BBR5_BOVIN Isoform 1 of Homeobox protein OS=Bos taurus OX=9913 GN=PITX3 PE=3 SV=1 CANONICAL=E1BBR5-1" }, "isoforms": [ { "isoform_ac": "E1BBR5-1", "url": "https://www.uniprot.org/uniprotkb/E1BBR5/entry#E1BBR5-1", "sequence": { "sequence": "MEFGLLSEAEARSPALSLSDAGTPHPPLPEHGCKGQEHSDSEKASVSLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGGFAAPLGGLVPPYEEVYPGYSYGNWPPKALGPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSISASMVPSGATAPGTVPGHGALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPTVPGPPPAANLSPCQYAVERPV", "length": 302, "header": "tr|E1BBR5-1|E1BBR5_BOVIN Isoform 1 of Homeobox protein OS=Bos taurus OX=9913 GN=PITX3 PE=3 SV=1 CANONICAL=E1BBR5-1" }, "locus": { "chromosome": "26", "start_pos": 22875889, "end_pos": 22874294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020847.5", "url": "https://www.ensembl.org/id/ENSBTAT00000020847.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020847.4", "url": "https://www.ensembl.org/id/ENSBTAP00000020847.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512000", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512000", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O35160-1", "protein_name": "Pituitary homeobox 3", "gene_name": "Pitx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFGLLGEAEARSPALSLSDAGTPHPPLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGGFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGAPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVPGPPPAANLSPCQYAVERPV", "length": 302 }, "evidence": [ { "id": "E1BBR5", "url": "https://omabrowser.org/oma/group/E1BBR5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O75364-1", "protein_name": "Pituitary homeobox 3", "gene_name": "PITX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYAVERPV", "length": 302 }, "evidence": [ { "id": "E1BBR5", "url": "https://omabrowser.org/oma/group/E1BBR5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P81062-1", "protein_name": "Pituitary homeobox 3", "gene_name": "Pitx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEFGLLGEAEARSPALSLSDAGTPHPPLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGGFAAPLGGLVPPYEEVYPGYTYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGAPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVPGPPPAANLSPCQYAVERPV", "length": 302 }, "evidence": [ { "id": "E1BBR5", "url": "https://omabrowser.org/oma/group/E1BBR5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BBR5", "url": "https://www.uniprot.org/uniprotkb/E1BBR5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BBR5", "url": "https://www.uniprot.org/uniprotkb/E1BBR5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BBR5", "url": "https://www.uniprot.org/uniprotkb/E1BBR5" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "E1BBR5", "url": "https://www.uniprot.org/uniprotkb/E1BBR5" } ], "pmid": "" }, { "name": "lens morphogenesis in camera-type eye", "id": "GO:0002089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002089", "evidence": [ { "database": "UniProtKB", "id": "E1BBR5", "url": "https://www.uniprot.org/uniprotkb/E1BBR5" } ], "pmid": "" }, { "name": "dopaminergic neuron differentiation", "id": "GO:0071542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071542", "evidence": [ { "database": "UniProtKB", "id": "E1BBR5", "url": "https://www.uniprot.org/uniprotkb/E1BBR5" } ], "pmid": "" }, { "name": "lens fiber cell differentiation", "id": "GO:0070306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070306", "evidence": [ { "database": "UniProtKB", "id": "E1BBR5", "url": "https://www.uniprot.org/uniprotkb/E1BBR5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BBR5", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:526765", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCGYCKV", "url": "https://omabrowser.org/oma/group/RCGYCKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BBR8", "url": "https://www.orthodb.org/?gene=E1BBR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015327660", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015327660", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BBR8", "url": "https://www.uniprot.org/uniprotkb/E1BBR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBR8-1", "url": "https://www.uniprot.org/uniprotkb/E1BBR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVTNESTQGNFILLGFSDRPHLERILFVVILIAYLLTLVGNTTIILVSRLDRYLHTPMYFFLTHLSLLDLSFTTSSIPQLLYNLNGHDKTISYTGCAIQLFLFLGLGGVECLLLAVMAYDRFVAVCKPLHYMVIMNPQLCLGLVSLAWGCGVANSLIMSPMTLWLPRCGYQKVDHFLCEMPALIRMACVNTAAVEGIAFILAIGIVLSPLVFILISYGYIVRAVLSIQSSSGRHKAFNTCGSHLTVVSLFYGNIIYMYMQPGASSSKDQGKFLTLFYNIVTPLLNPLIYTLRNKEVKGALRRLTLVNLSLGRNYNKRQC", "length": 320, "header": "tr|E1BBR8-1|E1BBR8_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2W3D PE=3 SV=2 CANONICAL=E1BBR8-1" }, "isoforms": [ { "isoform_ac": "E1BBR8-1", "url": "https://www.uniprot.org/uniprotkb/E1BBR8/entry#E1BBR8-1", "sequence": { "sequence": "MDVTNESTQGNFILLGFSDRPHLERILFVVILIAYLLTLVGNTTIILVSRLDRYLHTPMYFFLTHLSLLDLSFTTSSIPQLLYNLNGHDKTISYTGCAIQLFLFLGLGGVECLLLAVMAYDRFVAVCKPLHYMVIMNPQLCLGLVSLAWGCGVANSLIMSPMTLWLPRCGYQKVDHFLCEMPALIRMACVNTAAVEGIAFILAIGIVLSPLVFILISYGYIVRAVLSIQSSSGRHKAFNTCGSHLTVVSLFYGNIIYMYMQPGASSSKDQGKFLTLFYNIVTPLLNPLIYTLRNKEVKGALRRLTLVNLSLGRNYNKRQC", "length": 320, "header": "tr|E1BBR8-1|E1BBR8_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2W3D PE=3 SV=2 CANONICAL=E1BBR8-1" }, "locus": { "chromosome": "7", "start_pos": 41280693, "end_pos": 41279734, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000051947.2", "url": "https://www.ensembl.org/id/ENSBTAT00000051947.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049676.2", "url": "https://www.ensembl.org/id/ENSBTAP00000049676.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:526765", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526765", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5NCC8-1", "protein_name": "Olfactory receptor", "gene_name": "Or2w3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGATNDSTFSHFILIGFSDRPELERVLFAIILPAYLLTLLGNSIIILVSRLDPHLHTPMYFFLTHLSFLDLSFTSSSIPQLLYNLSGPDKTISYVGCALQLVLFLGLGGVECLLLAVMAYDRFVAVCKPLHYMVIMSPRLCVGLVSVAWSCGVANSLAMSPVTLSLPRCGHRRVDHFLCEMPALIRTACVNTAAVEGTVFVLAIGIVLSPLVFILVSYGYIVRAVLQIRSAAGRQKAFNTCGSHLTVVSLFYGNIIYMYMQPGNSSSQDQGKFLTLFYNIVTPLLNPLIYTLRNKEVKGALRRLLLGSRETGKVRAGSIRTRGKLSW", "length": 327 }, "evidence": [ { "id": "E1BBR8", "url": "https://omabrowser.org/oma/group/E1BBR8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BBR8", "url": "https://www.uniprot.org/uniprotkb/E1BBR8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "E1BBR8", "url": "https://www.uniprot.org/uniprotkb/E1BBR8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BBR8", "url": "https://www.uniprot.org/uniprotkb/E1BBR8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "E1BBR8", "url": "https://www.uniprot.org/uniprotkb/E1BBR8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BBR8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BBR8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BBR8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BBR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBR8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 308, "end_pos": 310 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BBR9-1", "uniprot_ac": "E1BBR9", "uniprot_id": "E1BBR9_BOVIN", "mass": { "chemical_mass": 75314.0, "monoisotopic_mass": 75314.0 }, "refseq": { "ac": "NP_001192667", "name": "protein SPT2 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192667" }, "gene_names": [ { "name": "SPTY2D1", "type": "recommended", "evidence": [ { "id": "E1BBR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" } ] }, { "name": "SPTY2D1", "type": "synonym", "evidence": [ { "id": "NP_001192667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192667" } ] } ], "protein_names": [ { "name": "Protein SPT2 homolog", "type": "recommended", "evidence": [ { "id": "E1BBR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBR9/entry#names_and_taxonomy" } ] }, { "name": "SPT2, Suppressor of Ty, domain containing 1", "type": "synonym", "evidence": [ { "id": "NP_001192667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192667" } ] }, { "name": "protein SPT2 homolog", "type": "synonym", "evidence": [ { "id": "NP_001192667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192667" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BBR9", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPTY2D1", "url": "https://www.uniprot.org/uniprotkb/E1BBR9", "locus": { "chromosome": "29", "start_pos": 26119994, "end_pos": 26103453, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001660", "url": "https://www.ensembl.org/id/ENSBTAG00000001660" } ] } } ], "crossref": [ { "id": "E1BBR9", "url": "https://alphafold.ebi.ac.uk/entry/E1BBR9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001660", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001660", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539967", "url": "https://www.ncbi.nlm.nih.gov/gene/539967", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054552", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054552", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539967", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539967", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPMATPH", "url": "https://omabrowser.org/oma/group/GPMATPH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BBR9", "url": "https://www.orthodb.org/?gene=E1BBR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22691", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22691", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22691:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22691:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08243", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08243", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192667", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192667", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BBR9", "url": "https://www.uniprot.org/uniprotkb/E1BBR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBR9-1", "url": "https://www.uniprot.org/uniprotkb/E1BBR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFREILLIASKAQGVNNVPKRYSLAVGPPKKDPKVKGVQSAAVQAFLRRKEEELRRKALEEKRRKEELVKKRIELKHDKKARAMAKRTKDNFHGYNGIPVEEKSRKRQAMQSHTSQGTDQEYEMEEEDEFLEYNQAESEQEYEEEQEPPKVESKPKVPLKSAPPVMNFNDLLRLAEKKQYEPVEIKVVKKTEERPMTAEELREREFLERKRRKRTPETDARLPPTRRVPSQKEGVGTKLSRGSGDMHPPCKGTVLPHPEKKPRPSPADEKRLHLSSSKSVPGERTKVAPGSCSQSSLHEGRDRPVFNGAGKPHPSTYSPSVPKTSAKGPQKSATEHKAKKSPPHPSHSRPGPMATPHNKAKSPGVRPPGSSSSSAPGRPSTGTARPTVSSGPMPKRQNGSSNSGPERSVSGNRKLTSDFSPPGRTVSGTSGLGRPASSSGGPGRPVSGSSGSGRPVGSSGGPGRPVSSLHDHRRPMSGSGPPGRSISGPGRSVSGPAPAGRPVSSSGPGRPVSSLGPGRTVNTSGPPLKPKCTVVSETISSKNIISRPSNGQMNGMKPSLSGYRSGPQRLPFPSGYKRQREYEEEEDDEEEYDSEMEDFIEDEGEPQEEISKHIREIFGYDRKKYKDESDYALRYMESSWKEQQKEEAKSLRLGMQEDLEEMRREEEEMRRRKAKKLKKR", "length": 681, "header": "tr|E1BBR9-1|E1BBR9_BOVIN Isoform 1 of Protein SPT2 homolog OS=Bos taurus OX=9913 GN=SPTY2D1 PE=3 SV=2 CANONICAL=E1BBR9-1" }, "isoforms": [ { "isoform_ac": "E1BBR9-1", "url": "https://www.uniprot.org/uniprotkb/E1BBR9/entry#E1BBR9-1", "sequence": { "sequence": "MDFREILLIASKAQGVNNVPKRYSLAVGPPKKDPKVKGVQSAAVQAFLRRKEEELRRKALEEKRRKEELVKKRIELKHDKKARAMAKRTKDNFHGYNGIPVEEKSRKRQAMQSHTSQGTDQEYEMEEEDEFLEYNQAESEQEYEEEQEPPKVESKPKVPLKSAPPVMNFNDLLRLAEKKQYEPVEIKVVKKTEERPMTAEELREREFLERKRRKRTPETDARLPPTRRVPSQKEGVGTKLSRGSGDMHPPCKGTVLPHPEKKPRPSPADEKRLHLSSSKSVPGERTKVAPGSCSQSSLHEGRDRPVFNGAGKPHPSTYSPSVPKTSAKGPQKSATEHKAKKSPPHPSHSRPGPMATPHNKAKSPGVRPPGSSSSSAPGRPSTGTARPTVSSGPMPKRQNGSSNSGPERSVSGNRKLTSDFSPPGRTVSGTSGLGRPASSSGGPGRPVSGSSGSGRPVGSSGGPGRPVSSLHDHRRPMSGSGPPGRSISGPGRSVSGPAPAGRPVSSSGPGRPVSSLGPGRTVNTSGPPLKPKCTVVSETISSKNIISRPSNGQMNGMKPSLSGYRSGPQRLPFPSGYKRQREYEEEEDDEEEYDSEMEDFIEDEGEPQEEISKHIREIFGYDRKKYKDESDYALRYMESSWKEQQKEEAKSLRLGMQEDLEEMRREEEEMRRRKAKKLKKR", "length": 681, "header": "tr|E1BBR9-1|E1BBR9_BOVIN Isoform 1 of Protein SPT2 homolog OS=Bos taurus OX=9913 GN=SPTY2D1 PE=3 SV=2 CANONICAL=E1BBR9-1" }, "locus": { "chromosome": "29", "start_pos": 26119404, "end_pos": 26103468, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002177.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002177.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002177.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002177.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539967", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539967", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I258-1", "protein_name": "Protein SPT2 homolog", "gene_name": "Spty2d1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFREILLIASKGQGVNHVPKRYSLAVGPPKKDPKVKGVQSAAVQAFLRRKEEELRRKALEEKRRKEELVKKRIELKHDKKARAMAKRTKDNFHGYDGIPIEEKSKKRQTVENHLNQGTDQEYEVEEEDFLDYSQAELEQEYEEEQEPPKTESKPKAPLKNAPPPMNFTDLLRLAEKKQFEPVEIKVVKKAEERPMTAEELREREFLERKHRKRKPEADVKLPPPVSKRAPPSHKDSVGTKLSKGTGDRQLSSKGLPFPHAEKKSRPSTAIEKQVALSSSKSMPGERTKAGSGSSSQPSLRESHNRPVFNGTGKPHPNTCSPSVPKTSASGTQKSSSEHKAKKPLPSHPSHSKPGPTVLSHNKAKSPGVRQLGSNSGSAPGRPSPGTAGPTVSSGAMPRRQNGSSSTGPEQSVSGIRKLASNSHPSGRTVNGTNGPGRPASSTTGPGRLINGPSGSGRPMSSSGGPGRPVHSPHDIRRPMNSLGSPGRSVSGPGRSVSGSVPAGRTASSGPGRPVSSLGPGRTVGSPGLPIKPKCTVVSETISSKNIISRSSNGQINGTKPFLSGYRSAQGPQRLPFPTGYKRPREYEDDDDDDEYDSEMDDFIEDEGEPQEEISKHIREIFGYDRKKYKDESDYALRYMESSWKEQQKEEAKSLRLGMQEDLEEMRREEEEMKRRKAKKLKRH", "length": 684 }, "evidence": [ { "id": "E1BBR9", "url": "https://omabrowser.org/oma/group/E1BBR9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q68FG3-1", "protein_name": "Protein SPT2 homolog", "gene_name": "Spty2d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFREILLIASKGQGVNHVPKRYSLAVGPPKKDPKVKGVQSAAVQAFLRRKEEELRQKALEEKKRKEELVKKRIELKHDKKARAMAKRTKDNFHGYDGIPVEEKTKKKQLVESHLNQGTDQEYDVEEEDFIDYNQAELDQDYEEEQEPPKAESKPKAPLKSAPSPMNFTDLLRLAEKKQFEPVEIKVVKKAEDRPLTAEELREREFLERKHRKKKPEPDAKLPPPVLKKAPSHKDIMGTKPSRGAGDRQLASKGLPFPQAEKKFRPSTASEKQAALSSPKSLPGERTKVGSGSSTQPSLREGHNRPVFNGAGKPRPSTCSPSVPKTPASGTQKSASEHKAKKPLPSHPSHSKPGPTVLSHNKSKSPGVRQPGSNSGSAPGQPNPGTARPTLSSGPVPRRQNGSSSSGPEQSAGGIRKLASNSHLSGRTLNGTNGPGRPASSSSGPGRPISGSAGSGRPVGSSGGPGQPVNNPHDLRRPMNSLSSPGRAVSGPGRSISGSIPAGRTVNSGPGRPVSSLGPGRAVSNPGLPTKPRCTVVSETISSKNIISRSSNGQINGMKPLLSGYRSAQGPQRLPFPTGYKRPREYEEDDDDEYDSEMDDFIEDEGEPQEEISKHIREIFGYDRKKYKDESDYALRYMESSWKEQQKEEAKSLRLGMQEDLEEMRREEEELKRRKAKKLKRH", "length": 682 }, "evidence": [ { "id": "E1BBR9", "url": "https://omabrowser.org/oma/group/E1BBR9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6DGN6-1", "protein_name": "Protein SPT2 homolog", "gene_name": "spty2d1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDFDSVLSIASQNQGLSSLPKRYSLKTGPPKKDLKVGGVNSAAVQAFLKKKAVEQKNKEQQDKKAKEDLLAKRVELKSDRKARAMASRTKDNFRGYNGIPVIDQPKKRQSKGSSTEEQQSSTKYEGGDYDDEDNFDYEGTDSESEPSRPVKPQAISRPEYSNRVENKPKKLSAPARPASSSMNFADLLKLAEKKQFEPVELKVVKKTEERLRTAEEIRELEMERRVKKLDKGKDVRSDKNSGQKDSRSQTSSNPQKKHVDRDGKNGRFPRPSEEKHQSSSTSKKPKLQASSERTPTSAKLHGDRSNSGSSGALNSKSAMKNGASFQAKQAPPRPSQGQRPATPSDLTPRKGNVSLTQAKSSISGSCPPGAARPGQGPHKNSAHGRPSNFSTSGPSQKPANPGKLSRPGSNAPPRPGGSGVVRPFTGDPSKQPRPGGNLQSQQFPGSSRASLNGPKRMERGVSGSQINRMSSGPGRSQCTVVSETISTKNITPRPGMVQRPPGPQGPRTVIGPSGHRILVKPSGPALPPITSSYKRKFEDEEEYDSEMDDFIDDEGEDQDEISKHIREIFGYDKNKYKDESDYALKFMESSWKEQQKEEARSLRMAVLEDEEEERRELEEMQRKNAKKRK", "length": 629 }, "evidence": [ { "id": "E1BBR9", "url": "https://omabrowser.org/oma/group/E1BBR9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8IMP6-1", "protein_name": "Protein SPT2 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDFGDLLRYAKKNSDAVTKEVGQGKYYSTKYSPPKKQSKESKQLSSNIQKFLQKKEAEEAEKKRLERQKLNDLLAKRDEKSKNKIRKMLKVTKSANKSVLEDAKDYEGAIDGHEAGEGQGDDYGYVSTEANAFYDKYIEKVRDVQEDKGFTPSRPQSLKDLSGTKERVKAAITREREEAKGNTRQKSSTSTLPSSATKSKESSVARSYSTSKTLYDPNAEKLEEERKKRQEEEQRRAKIKRPAQPPPMDFQALLRLAEKKQHEPVVFEVEKKKEPERLLSAREKRELEERQRQQEQRAQRLKMRESEGKETPKSIPNRMEPNGRIPKLNQAKPANAPSDSFKKPTAPQPTKSSASSTSLSSSNSHSSASRSSVSSSRPATKSAQLTARPGATASAVGKPSSSSSRDVPSKNPYAATSLKGTVREFPPRDQSSISTLDRRKIPAAAKTRQTPSSDVQRSQGGRQFPPADVKRRKPNEPPVTKRRIYDDDDEDEYDSELDDFIDDGDCEEDISSHIRDIFGYDKRRYQGIDDDDRGMESSFAQVQREEFISKKLGMQEDLEDMRMEAAHKKQKKLVAKISSRS", "length": 581 }, "evidence": [ { "id": "E1BBR9", "url": "https://omabrowser.org/oma/group/E1BBR9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "transcription by RNA polymerase I", "id": "GO:0006360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006360", "evidence": [ { "database": "UniProtKB", "id": "E1BBR9", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BBR9", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "E1BBR9", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "E1BBR9", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BBR9", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "E1BBR9", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" } ], "pmid": "" }, { "name": "histone chaperone activity", "id": "GO:0140713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140713", "evidence": [ { "database": "UniProtKB", "id": "E1BBR9", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BBR9", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1BBR9", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BBR9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 681, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BBR9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BBR9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BBR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBR9" }, { "id": "PF22878", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SPT2 homolog N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 90, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 399, "end_pos": 401 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BBS0-1", "uniprot_ac": "E1BBS0", "uniprot_id": "E1BBS0_BOVIN", "mass": { "chemical_mass": 25872.0, "monoisotopic_mass": 25872.0 }, "refseq": { "ac": "NP_001192692", "name": "transmembrane protein 127", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192692" }, "gene_names": [ { "name": "TMEM127", "type": "recommended", "evidence": [ { "id": "E1BBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBS0" } ] }, { "name": "TMEM127", "type": "synonym", "evidence": [ { "id": "NP_001192692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192692" } ] } ], "protein_names": [ { "name": "Transmembrane protein 127", "type": "synonym", "evidence": [ { "id": "E1BBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBS0/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 127", "type": "synonym", "evidence": [ { "id": "NP_001192692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192692" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BBS0", "url": "https://www.uniprot.org/uniprotkb/E1BBS0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM127", "url": "https://www.uniprot.org/uniprotkb/E1BBS0", "locus": { "chromosome": "11", "start_pos": 2355706, "end_pos": 2367369, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015667", "url": "https://www.ensembl.org/id/ENSBTAG00000015667" } ] } } ], "crossref": [ { "id": "E1BBS0", "url": "https://alphafold.ebi.ac.uk/entry/E1BBS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015667", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015667", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "513620", "url": "https://www.ncbi.nlm.nih.gov/gene/513620", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513620", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513620", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVFWVIA", "url": "https://omabrowser.org/oma/group/CVFWVIA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BBS0", "url": "https://www.orthodb.org/?gene=E1BBS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28358", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28358", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28358:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28358:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192692", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192692", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BBS0", "url": "https://www.uniprot.org/uniprotkb/E1BBS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBS0-1", "url": "https://www.uniprot.org/uniprotkb/E1BBS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYAPGGAGLPGGRRRRSPGGSTLPKQPERSLASALPGALSITALCTALAEPAWLHIHGGTCSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP", "length": 238, "header": "tr|E1BBS0-1|E1BBS0_BOVIN Isoform 1 of Transmembrane protein 127 OS=Bos taurus OX=9913 GN=TMEM127 PE=4 SV=3 CANONICAL=E1BBS0-1" }, "isoforms": [ { "isoform_ac": "E1BBS0-1", "url": "https://www.uniprot.org/uniprotkb/E1BBS0/entry#E1BBS0-1", "sequence": { "sequence": "MYAPGGAGLPGGRRRRSPGGSTLPKQPERSLASALPGALSITALCTALAEPAWLHIHGGTCSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP", "length": 238, "header": "tr|E1BBS0-1|E1BBS0_BOVIN Isoform 1 of Transmembrane protein 127 OS=Bos taurus OX=9913 GN=TMEM127 PE=4 SV=3 CANONICAL=E1BBS0-1" }, "locus": { "chromosome": "11", "start_pos": 2366725, "end_pos": 2356461, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020807.4", "url": "https://www.ensembl.org/id/ENSBTAT00000020807.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020807.4", "url": "https://www.ensembl.org/id/ENSBTAP00000020807.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:513620", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513620", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BIG9-1", "protein_name": "Transmembrane protein 127", "gene_name": "TMEM127", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYAPGGAGLPGGRRRRSPGGSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGTCSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP", "length": 238 }, "evidence": [ { "id": "E1BBS0", "url": "https://omabrowser.org/oma/group/E1BBS0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75204-1", "protein_name": "Transmembrane protein 127", "gene_name": "TMEM127", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYAPGGAGLPGGRRRRSPGGSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGTCSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP", "length": 238 }, "evidence": [ { "id": "E1BBS0", "url": "https://omabrowser.org/oma/group/E1BBS0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BGP5-1", "protein_name": "Transmembrane protein 127", "gene_name": "Tmem127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYAPGGAGLPGGRRRRSPGSSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGTCSRQELGVSDVLGYVNPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENDPYPAEYEVINQFQPPPAYTP", "length": 238 }, "evidence": [ { "id": "E1BBS0", "url": "https://omabrowser.org/oma/group/E1BBS0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "E1BBS0", "url": "https://www.uniprot.org/uniprotkb/E1BBS0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BBS0", "url": "https://www.uniprot.org/uniprotkb/E1BBS0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BBS0", "url": "https://www.uniprot.org/uniprotkb/E1BBS0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "E1BBS0", "url": "https://www.uniprot.org/uniprotkb/E1BBS0" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "E1BBS0", "url": "https://www.uniprot.org/uniprotkb/E1BBS0" } ], "pmid": "" }, { "name": "regulation of TOR signaling", "id": "GO:0032006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032006", "evidence": [ { "database": "UniProtKB", "id": "E1BBS0", "url": "https://www.uniprot.org/uniprotkb/E1BBS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "E1BBS0", "url": "https://www.uniprot.org/uniprotkb/E1BBS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BBS0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 238, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BBS0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BBS0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBS0" }, { "id": "PF20517", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20517" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein 127 transmembrane region", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 196, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BBS2-1", "uniprot_ac": "E1BBS2", "uniprot_id": "E1BBS2_BOVIN", "mass": { "chemical_mass": 46045.0, "monoisotopic_mass": 46045.0 }, "refseq": { "ac": "XP_002697764", "name": "histamine H4 receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697764" }, "gene_names": [ { "name": "HRH4", "type": "recommended", "evidence": [ { "id": "E1BBS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBS2" } ] }, { "name": "HRH4", "type": "synonym", "evidence": [ { "id": "XP_002697764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697764" } ] } ], "protein_names": [ { "name": "Histamine receptor H4", "type": "synonym", "evidence": [ { "id": "E1BBS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBS2/entry#names_and_taxonomy" } ] }, { "name": "histamine H4 receptor", "type": "synonym", "evidence": [ { "id": "XP_002697764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697764" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BBS2", "url": "https://www.uniprot.org/uniprotkb/E1BBS2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HRH4", "url": "https://www.uniprot.org/uniprotkb/E1BBS2", "locus": { "chromosome": "24", "start_pos": 32185938, "end_pos": 32225573, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020467", "url": "https://www.ensembl.org/id/ENSBTAG00000020467" } ] } } ], "crossref": [ { "id": "E1BBS2", "url": "https://alphafold.ebi.ac.uk/entry/E1BBS2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020467", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020467", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "783354", "url": "https://www.ncbi.nlm.nih.gov/gene/783354", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:783354", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783354", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVFWLIT", "url": "https://omabrowser.org/oma/group/CVFWLIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BBS2", "url": "https://www.orthodb.org/?gene=E1BBS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24247:SF199", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24247:SF199", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-390650", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-390650", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002697764", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697764", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BBS2", "url": "https://www.uniprot.org/uniprotkb/E1BBS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBS2-1", "url": "https://www.uniprot.org/uniprotkb/E1BBS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYTHGINSSHVMPFTNDTNSSAVMPASKDIYSFSNIALAFLMSLLAFAIMLGNAVVILAFVVDKNLRHRSNYFFLNLAISDFFVGMISIPLFIPHKLFNWEFENNICVFWLTTDYLLCTASVYNIVLISFDRYQSVSNAVSYRARHTGTLKTVTLMVAVWVAAFLVHGPILVSEVRKELRGDCKPEFLKKKHILALTLVFEFLIPVLLVAYFNMYIYWSLWKRSHLSRGHSGFISAPSISSGRSFRNGLFSRPSLSNLEESAASLRSEKSGRKSSLFSSLRTQVNSLTASKTSSLSHSDSLVLHQREHLELCRGKKLAKSLAILLGVFAVCWAPYSLFTIIHSCHGTLSDFLNPVYEFTFWLQWFNSFVNPFLYPLCHKRFQKAFLKLFRVKKQSISSHNRSTSS", "length": 405, "header": "tr|E1BBS2-1|E1BBS2_BOVIN Isoform 1 of Histamine receptor H4 OS=Bos taurus OX=9913 GN=HRH4 PE=3 SV=3 CANONICAL=E1BBS2-1" }, "isoforms": [ { "isoform_ac": "E1BBS2-1", "url": "https://www.uniprot.org/uniprotkb/E1BBS2/entry#E1BBS2-1", "sequence": { "sequence": "MYTHGINSSHVMPFTNDTNSSAVMPASKDIYSFSNIALAFLMSLLAFAIMLGNAVVILAFVVDKNLRHRSNYFFLNLAISDFFVGMISIPLFIPHKLFNWEFENNICVFWLTTDYLLCTASVYNIVLISFDRYQSVSNAVSYRARHTGTLKTVTLMVAVWVAAFLVHGPILVSEVRKELRGDCKPEFLKKKHILALTLVFEFLIPVLLVAYFNMYIYWSLWKRSHLSRGHSGFISAPSISSGRSFRNGLFSRPSLSNLEESAASLRSEKSGRKSSLFSSLRTQVNSLTASKTSSLSHSDSLVLHQREHLELCRGKKLAKSLAILLGVFAVCWAPYSLFTIIHSCHGTLSDFLNPVYEFTFWLQWFNSFVNPFLYPLCHKRFQKAFLKLFRVKKQSISSHNRSTSS", "length": 405, "header": "tr|E1BBS2-1|E1BBS2_BOVIN Isoform 1 of Histamine receptor H4 OS=Bos taurus OX=9913 GN=HRH4 PE=3 SV=3 CANONICAL=E1BBS2-1" }, "locus": { "chromosome": "24", "start_pos": 32225490, "end_pos": 32211823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048201.4", "url": "https://www.ensembl.org/id/ENSBTAT00000048201.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045285.3", "url": "https://www.ensembl.org/id/ENSBTAP00000045285.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:783354", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783354", "resource": "KEGG Pathway" }, { "id": "R-BTA-390650", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-390650", "resource": "Reactome", "description": "Histamine receptors" }, { "id": "R-BTA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1S318-1", "protein_name": "Histamine receptor H4", "gene_name": "HRH4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAINDTNTNTLPLNTRIALAFLMSLLALVIMLGNAVVILAFVVDKNLRHRSNYFLLNLAISDFFVGVISIPLYIPHTLFKWKLEDNICAFWLIIDYLLCTASVYNIVLISFDRYQSVSNAVSYRTQHTGILKIVALMVGVWVLAFLVHGPVILVSEAWKQGKQDCEPGFLKEWYVLAITLFFEFLAPVLLVAYFNLYIYWSLWKRGHLSRCQSHCGLTPVSSGSWGHSFRCGLFSRTSLSDPKEAAASLHSERPRRKSTLWFSLRTRMSSLTASNKGFLSHSDSLALHQKEHLELLRARKLARSLAILLGVFAICWAPYSLLTIIRSVYPTNPFPSTAVYKFAFWLQWFNSCVNPFLYPLCHKRFQKAFLKIFCLKKQSTLSHNRSTSS", "length": 390 }, "evidence": [ { "id": "E1BBS2", "url": "https://omabrowser.org/oma/group/E1BBS2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q91ZY1-1", "protein_name": "Histamine H4 receptor", "gene_name": "Hrh4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSESNGTDVLPLTAQVPLAFLMSLLAFAITIGNAVVILAFVADRNLRHRSNYFFLNLAISDFFVGVISIPLYIPHTLFNWNFGSGICMFWLITDYLLCTASVYSIVLISYDRYQSVSNAVRYRAQHTGILKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTEECEPGFVTEWYILAITAFLEFLLPVSLVVYFSVQIYWSLWKRGSLSRCPSHAGFIATSSRGTGHSRRTGLACRTSLPGLKEPAASLHSESPRGKSSLLVSLRTHMSGSIIAFKVGSFCRSESPVLHQREHVELLRGRKLARSLAVLLSAFAICWAPYCLFTIVLSTYRRGERPKSIWYSIAFWLQWFNSLINPFLYPLCHRRFQKAFWKILCVTKQPAPSQTQSVSS", "length": 391 }, "evidence": [ { "id": "E1BBS2", "url": "https://omabrowser.org/oma/group/E1BBS2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91ZY2-1", "protein_name": "Histamine H4 receptor", "gene_name": "Hrh4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSESNSTGILPPAAQVPLAFLMSSFAFAIMVGNAVVILAFVVDRNLRHRSNYFFLNLAISDFLVGLISIPLYIPHVLFNWNFGSGICMFWLITDYLLCTASVYNIVLISYDRYQSVSNAVSYRAQHTGIMKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTKDCEPGFVTEWYILTITMLLEFLLPVISVAYFNVQIYWSLWKRRALSRCPSHAGFSTTSSSASGHLHRAGVACRTSNPGLKESAASRHSESPRRKSSILVSLRTHMNSSITAFKVGSFWRSESAALRQREYAELLRGRKLARSLAILLSAFAICWAPYCLFTIVLSTYPRTERPKSVWYSIAFWLQWFNSFVNPFLYPLCHRRFQKAFWKILCVTKQPALSQNQSVSS", "length": 391 }, "evidence": [ { "id": "E1BBS2", "url": "https://omabrowser.org/oma/group/E1BBS2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H3N8-1", "protein_name": "Histamine H4 receptor", "gene_name": "HRH4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVGVISIPLYIPHTLFEWDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSVSNAVSYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS", "length": 390 }, "evidence": [ { "id": "E1BBS2", "url": "https://omabrowser.org/oma/group/E1BBS2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BBS2", "url": "https://www.uniprot.org/uniprotkb/E1BBS2" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377747" }, "gene_names": [ { "name": "OR1J32", "type": "recommended", "evidence": [ { "id": "E1BBT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBT1" } ] }, { "name": "OR1J32", "type": "synonym", "evidence": [ { "id": "NP_001377747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377747" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BBT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBT1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 1 subfamily J member 32", "type": "synonym", "evidence": [ { "id": "NP_001377747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377747" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377747" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BBT1", "url": "https://www.uniprot.org/uniprotkb/E1BBT1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BBT1", "url": "https://www.uniprot.org/uniprotkb/E1BBT1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR1J32", "url": "https://www.uniprot.org/uniprotkb/E1BBT1", "locus": { "chromosome": "11", "start_pos": 93493070, "end_pos": 93492129, "strand": "-", "evidence": 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"id": "bta:119646078", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:119646078", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LNMQTQH", "url": "https://omabrowser.org/oma/group/LNMQTQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377747", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BBT1", "url": "https://www.uniprot.org/uniprotkb/E1BBT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBT1-1", "url": "https://www.uniprot.org/uniprotkb/E1BBT1-1", "database": "UniProtKB", "categories": [ "Protein" 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"E1BBT1", "url": "https://www.uniprot.org/uniprotkb/E1BBT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BBT1", "url": "https://www.uniprot.org/uniprotkb/E1BBT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BBT1", "url": "https://www.uniprot.org/uniprotkb/E1BBT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BBT1-F1", "pdb_chain": "global", 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"MLTLARSFCSLQGEFCQAMDSFTTVSHVGMCEETDASFNVFTLKLQFDRSHCQSLRFHQNMELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKSSAKSPGPTRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM", "length": 425, "header": "tr|E1BBU3-1|E1BBU3_BOVIN Isoform 1 of Doublecortin OS=Bos taurus OX=9913 GN=DCX PE=4 SV=4 CANONICAL=E1BBU3-1" }, "isoforms": [ { "isoform_ac": "E1BBU3-1", "url": "https://www.uniprot.org/uniprotkb/E1BBU3/entry#E1BBU3-1", "sequence": { "sequence": "MLTLARSFCSLQGEFCQAMDSFTTVSHVGMCEETDASFNVFTLKLQFDRSHCQSLRFHQNMELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKSSAKSPGPTRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM", "length": 425, "header": "tr|E1BBU3-1|E1BBU3_BOVIN Isoform 1 of Doublecortin OS=Bos taurus OX=9913 GN=DCX PE=4 SV=4 CANONICAL=E1BBU3-1" }, "locus": { "chromosome": "X", "start_pos": 59588473, "end_pos": 59472985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026104.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026104.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026104.7", "url": "https://www.ensembl.org/id/ENSBTAP00000026104.7" } ] } }, { "isoform_ac": "G3MYK0-1", "url": "https://www.uniprot.org/uniprotkb/E1BBU3/entry#G3MYK0-1", "sequence": { "sequence": "MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKSSAKSPGPTRRSKSPADSGNDQDGPVPASVLG", "length": 324, "header": "tr|G3MYK0-1|E1BBU3_BOVIN Computationally mapped isoform of Doublecortin OS=Bos taurus OX=9913 GN=DCX PE=4 SV=3 CANONICAL=E1BBU3-1" }, "locus": { "chromosome": "X", "start_pos": 59587956, "end_pos": 59473013, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066028.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066028.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054634.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054634.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 349, "start_aa": "Thr", "end_pos": 349, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr349", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" }, { "name": "regulation of postsynapse assembly", "id": "GO:0150052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150052", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BBU3", "url": "https://www.uniprot.org/uniprotkb/E1BBU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BBV0-1", "uniprot_ac": "E1BBV0", "uniprot_id": "E1BBV0_BOVIN", "mass": { "chemical_mass": 58040.0, "monoisotopic_mass": 58040.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF703", "type": "recommended", "evidence": [ { "id": "E1BBV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ] } ], "protein_names": [ { "name": "Zinc finger protein 703", "type": "synonym", "evidence": [ { "id": "E1BBV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBV0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF703", "url": "https://www.uniprot.org/uniprotkb/E1BBV0", "locus": { "chromosome": "27", "start_pos": 32982448, "end_pos": 32978490, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013943", "url": "https://www.ensembl.org/id/ENSBTAG00000013943" } ] } } ], "crossref": [ { "id": "E1BBV0", "url": "https://alphafold.ebi.ac.uk/entry/E1BBV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013943", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013943", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SQAPHMD", "url": "https://omabrowser.org/oma/group/SQAPHMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12522", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12522", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12522:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12522:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBV0-1", "url": "https://www.uniprot.org/uniprotkb/E1BBV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDSPAGSNPRTPESSGSGSGGGGKRPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAANGLGAEKDPGRSASGAASASAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSSSSSSSSLSPGDKAGFRVPSAACTPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKTGASGELDKKDQESKPSPEPAAVSRSSSGDPGPHGGGGGGEPGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSGCSTCSAHDPAGPGLKAGGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLATYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRSPHTLGLNRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "length": 587, "header": "tr|E1BBV0-1|E1BBV0_BOVIN Isoform 1 of Zinc finger protein 703 OS=Bos taurus OX=9913 GN=ZNF703 PE=3 SV=3 CANONICAL=E1BBV0-1" }, "isoforms": [ { "isoform_ac": "E1BBV0-1", "url": "https://www.uniprot.org/uniprotkb/E1BBV0/entry#E1BBV0-1", "sequence": { "sequence": "MSDSPAGSNPRTPESSGSGSGGGGKRPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAANGLGAEKDPGRSASGAASASAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSSSSSSSSLSPGDKAGFRVPSAACTPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKTGASGELDKKDQESKPSPEPAAVSRSSSGDPGPHGGGGGGEPGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSGCSTCSAHDPAGPGLKAGGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLATYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRSPHTLGLNRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "length": 587, "header": "tr|E1BBV0-1|E1BBV0_BOVIN Isoform 1 of Zinc finger protein 703 OS=Bos taurus OX=9913 GN=ZNF703 PE=3 SV=3 CANONICAL=E1BBV0-1" }, "locus": { "chromosome": "27", "start_pos": 32981444, "end_pos": 32978689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018525.8", "url": "https://www.ensembl.org/id/ENSBTAT00000018525.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018525.6", "url": "https://www.ensembl.org/id/ENSBTAP00000018525.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ABF5-1", "protein_name": "Zinc finger protein 703", "gene_name": "Zfp703", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDSPAGSNPRTPESSGSGGSGGGGKRPAVPAVVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAANGLGSEKDPSRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDGGSSSVSSTTSSSSSSPGDKAGFRVPSAACPPFPPHGAAVSTSSNSSSPGGSRGGSPHHSDCKSGSGGAGGGGELDKKDQEAKPSPEPAAGSRGSSGDSAHGGPEATASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHSASHLGGSSCSTCSAHDPAGPSLKASGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASSLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRSPHTLGLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "length": 593 }, "evidence": [ { "id": "E1BBV0", "url": "https://omabrowser.org/oma/group/E1BBV0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RX82-1", "protein_name": "Zinc finger protein 703", "gene_name": "ZNF703", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSDSPAGSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAANGLGAEKDPSRSASGAASASAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSLSPGDKAGFRVPSAACTPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGAGGSGELDKKDQEPKPSPEPAAVSRGNGGEPGGHSGSGTEAGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPGLKAGGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPTAPGSPGSLSLRSPHTLGLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "length": 591 }, "evidence": [ { "id": "E1BBV0", "url": "https://omabrowser.org/oma/group/E1BBV0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0CL69-1", "protein_name": "Zinc finger protein 703", "gene_name": "Znf703", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDSPAGSNPRTPESSGSGGGSSSGGGGGKRPAVPAVVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAANGLGSEKDPSRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTTSSSSSSPGDKAGFRVPSAACPPFPPHGASVSTSSNSSSPGGSRGGSPHHSDCKNGGGGAGELDKKEQEAKPSPEPAAGSRGSGGDSAHGGPEATASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHSASHLGGSSCSTCSAHDPTGPSLKASGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASSLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRSPHTLGLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "length": 594 }, "evidence": [ { "id": "E1BBV0", "url": "https://omabrowser.org/oma/group/E1BBV0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q90ZE2-1", "protein_name": "Zinc finger protein 703", "gene_name": "znf703", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSELPPGFAVSPRNQQTFKSHYITNDSSPTCLGLQVDSIASLPYRDPARQEKRLPIRILKMLTAHTSHILHPEYLQPLSSAPVSIELDAKKSPLALLAQTCSQIGKPDPPPSSKLGSLSSSSHGDKDSRSSSSSLKSGEHQNLDDKSSFKPYSKTGSECRKEGAGINSSADKAGFRVPNGSSSSVTCTSLPPHAPSPRASSPQQTSGQSHTHRQSQSPLSQKTAHLQTTHMDSKAAGSDPGNDSSSSGSDRNGKKDSDHNKSSLDVVQIANSSHARASVNSSSASSSSSPQPDSKTDSQPPQPSLGTGHIAPVSPFKPGHSVFPLPSSTMGYHGSIVGAYTGYPSQFVPGLDPAKSSLGMGVPGKHPSSSPLTGASPPSFMQGLCRDPYCLTYPNAPHLGGSNCSSCVHDPSSALKSGFPLMYPTHHLHSLHPSSLSSSATSSLSHPLYTYGFMLPNETLPHACNWVSVGGPCDKRFATSEELLAHLRTHTALPGVDGKLLSGYPSSVSSAASCHLHLPPPSSPGALPSSLSLRGSPGLGLARYHPYGKAHLPGAPSLPMHSLPATAPYYSPYALYSQRLGSASALGYQ", "length": 589 }, "evidence": [ { "id": "E1BBV0", "url": "https://omabrowser.org/oma/group/E1BBV0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9H7S9-1", "protein_name": "Zinc finger protein 703", "gene_name": "ZNF703", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDSPAGSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRNPHTLGLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "length": 590 }, "evidence": [ { "id": "E1BBV0", "url": "https://omabrowser.org/oma/group/E1BBV0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0017015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017015", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" }, { "name": "mammary gland epithelial cell differentiation", "id": "GO:0060644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060644", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" }, { "name": "cellular response to estradiol stimulus", "id": "GO:0071392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071392", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" }, { "name": "positive regulation of mammary gland epithelial cell proliferation", "id": "GO:0033601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033601", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BBV0", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BBV0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 587, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BBV0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BBV0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BBV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBV0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 453, "end_pos": 486, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BBV1-1", "uniprot_ac": "E1BBV1", "uniprot_id": "E1BBV1_BOVIN", "mass": { "chemical_mass": 89867.0, "monoisotopic_mass": 89867.0 }, "refseq": {}, "gene_names": [ { "name": "RSBN1", "type": "recommended", "evidence": [ { "id": "E1BBV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBV1" } ] } ], "protein_names": [ { "name": "Round spermatid basic protein 1", "type": "synonym", "evidence": [ { "id": "E1BBV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBV1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BBV1", "url": "https://www.uniprot.org/uniprotkb/E1BBV1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RSBN1", "url": "https://www.uniprot.org/uniprotkb/E1BBV1", "locus": { "chromosome": "3", "start_pos": 29618905, "end_pos": 29579106, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000031940", "url": "https://www.ensembl.org/id/ENSBTAG00000031940" } ] } } ], "crossref": [ { "id": "E1BBV1", "url": "https://alphafold.ebi.ac.uk/entry/E1BBV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000031940", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000031940", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR026306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:508231", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508231", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SQCMENI", "url": "https://omabrowser.org/oma/group/SQCMENI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BBV1", "url": "https://www.orthodb.org/?gene=E1BBV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13354", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13354", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13354:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13354:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28448", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28448", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BBV1", "url": "https://www.uniprot.org/uniprotkb/E1BBV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBV1-1", "url": "https://www.uniprot.org/uniprotkb/E1BBV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSSGRRMAEKWRVGERLQCPAGRARAALARYADGGAVGPFKCVFVGEMAAQVGAVRVVRAVAAQEEADKDGKEKPHAGVSPRGVKRQRRASSGGSQEKRGRPSQDPPLAPPHRRRRSRQHPGPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPAVAAPLPAPGTSALFTFSPLTVSAAGPKHKGHKERHKHHHHRGSDGDPGPCGELKHKDKQENGERTGGVPLLKAPKRETPDENGKTQRADDFVLKKIKKKKKKKHREDMRGRRLKMYNKEVQTICAGLTRISKEILTQGQINSTSGVNKESFRYLKDEQLCRLNLGMQEYRVPQGVQTPFMTHQEHSIRRNFLKTGTKFSNFIHEEHQSNGGALVLHAYMDELSFLSPMEMERFSEEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKKDIETTTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKMTLPWGTLSSLRLQCRSQSDDGPIMWVRPGEQMIPTADMPKSPFKRRRSMNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHPVVDASQNTEGSSNVDCDLTGKQELEVDSQCVRIKTESEETCTETQLLTTASSSFPPSSELNLQQDQMTQSIPVLKVESRLDSDQQHSLQEHSSTPV", "length": 801, "header": "tr|E1BBV1-1|E1BBV1_BOVIN Isoform 1 of Round spermatid basic protein 1 OS=Bos taurus OX=9913 GN=RSBN1 PE=3 SV=2 CANONICAL=E1BBV1-1" }, "isoforms": [ { "isoform_ac": "E1BBV1-1", "url": "https://www.uniprot.org/uniprotkb/E1BBV1/entry#E1BBV1-1", "sequence": { "sequence": "MFSSGRRMAEKWRVGERLQCPAGRARAALARYADGGAVGPFKCVFVGEMAAQVGAVRVVRAVAAQEEADKDGKEKPHAGVSPRGVKRQRRASSGGSQEKRGRPSQDPPLAPPHRRRRSRQHPGPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPAVAAPLPAPGTSALFTFSPLTVSAAGPKHKGHKERHKHHHHRGSDGDPGPCGELKHKDKQENGERTGGVPLLKAPKRETPDENGKTQRADDFVLKKIKKKKKKKHREDMRGRRLKMYNKEVQTICAGLTRISKEILTQGQINSTSGVNKESFRYLKDEQLCRLNLGMQEYRVPQGVQTPFMTHQEHSIRRNFLKTGTKFSNFIHEEHQSNGGALVLHAYMDELSFLSPMEMERFSEEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKKDIETTTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKMTLPWGTLSSLRLQCRSQSDDGPIMWVRPGEQMIPTADMPKSPFKRRRSMNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHPVVDASQNTEGSSNVDCDLTGKQELEVDSQCVRIKTESEETCTETQLLTTASSSFPPSSELNLQQDQMTQSIPVLKVESRLDSDQQHSLQEHSSTPV", "length": 801, "header": "tr|E1BBV1-1|E1BBV1_BOVIN Isoform 1 of Round spermatid basic protein 1 OS=Bos taurus OX=9913 GN=RSBN1 PE=3 SV=2 CANONICAL=E1BBV1-1" }, "locus": { "chromosome": "3", "start_pos": 29618232, "end_pos": 29579168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026134.5", "url": "https://www.ensembl.org/id/ENSBTAT00000026134.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026134.4", "url": "https://www.ensembl.org/id/ENSBTAP00000026134.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:508231", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508231", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A1U7-1", "protein_name": "Round spermatid basic protein 1", "gene_name": "Rsbn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFRSTRTTDQWRAGERLQCPAGHARAALARTADGGAVGPFKCVFVGEMAAQVGAVRVVRAVAAQEEPDKEGKEKPHVGVSPRGVKRQRRVSSGGSQEKRGRPSQDPPLAPPHRRRRSRQHPGPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPAVAAPLPAPGTSALFTFSPLTVSAAGPKHKGHKERHKHHHHRGSDGDPVACVPGDLKHKDKQENGERSGGVPLMKAPKRETADENGKTQRADDFVLKKIKKKKKKKHREDMRGRRLKMYNKEVQTVCAGLTRISKEILTQGQLNSTSGVNKESFRYLKDEQLCRLNLGMQEYRVPQGVQTPFTTHQEHSIRRNFLKTGTKFSNFIHEEHQSNGGALVLHAYMDELSFLSPMEMERFSEEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKKDIETTTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKMTLPWGTLSSLQLQCRSQSDDGPIMWVRPGEQMIPTADMPKSPFKRRRSMNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHPVVETAQNTESNSNMDCGLEVDSQCVRIKTESEERCTEMQLLTTASSSFPLPSELHLQDLKTQPIPVFKVESRLDSDQQHSLQAHPSTPV", "length": 795 }, "evidence": [ { "id": "E1BBV1", "url": "https://omabrowser.org/oma/group/E1BBV1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LIT1-1", "protein_name": "Round spermatid basic protein 1", "gene_name": "RSBN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEKWRVGERLQCPAGRARAAPARYADGGAVGPFKCVFVGEMAAQVGAVRVVRAVAAQEEPDKEGKEKPHAGVSPRGVKRQRRASSGGSQEKRGRPSQDPPLAPPHRRRRSRQHPGPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPAVAAPLPAPGTSALFTFSPLTVSAAGPKHKGHKERHKHHHHRGSDGDPSSCVPGELKHKDKQENGERTGGVPLIKAPKRETPDENGKTQRADDFVLKKIKKKKKKKHREDMRGRRLKMYNKEVQTVCAGLTRISKEILTQGQINSTSGVNKESFRYLKDEQLCRLNLGMQEYRVPQGVQTPFMTHQEHSIRRNFLKTGTKFSNFIHEEHQSNGGALVLHAYMDELSFLSPMEMERFSEEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKKDIETTTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKMTLPWGTLSSLRLQCRSQSDDGPIMWVRPGEQMIPTADMPKSPFKRRRSMNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHPVVEASQNTESSSSTDCDLNGKRELEVDSQCVRIKTESEETCTEMQLLTTASSSFPPSSELNLQQDQMTQPLPVLKVESRLDSDQQHNLQEHSSTPV", "length": 796 }, "evidence": [ { "id": "E1BBV1", "url": "https://omabrowser.org/oma/group/E1BBV1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5VWQ0-1", "protein_name": "Lysine-specific demethylase 9", "gene_name": "RSBN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFISGRRTADKWRAEERLQCPAGSARAALARCADGGAVGPFKCVFVGEMAAQVGAVRVVRAVAAQEEPDKEGKEKPHAGVSPRGVKRQRRSSSGGSQEKRGRPSQEPPLAPPHRRRRSRQHPGPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPAVAAPLPAPSTSALFTFSPLTVSAAGPKHKGHKERHKHHHHRGPDGDPSSCGTDLKHKDKQENGERTGGVPLIKAPKRETPDENGKTQRADDFVLKKIKKKKKKKHREDMRGRRLKMYNKEVQTVCAGLTRISKEILTQGQINSTSGLNKESFRYLKDEQLCRLNLGMQEYRVPQGVQTPFMTHQEHSIRRNFLKTGTKFSNFIHEEHQSNGGALVLHAYMDELSFLSPMEMERFSEEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKKDIETTTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKMTLPWGTLSSLRLQCRSQSDDGPIMWVRPGEQMIPTADMPKSPFKRRRSMNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHPVVEATQNTESNSNMDCGLTGKRELEVDSQCVRIKTESEEACTEIQLLTTASSSFPPASELNLQQDQKTQPIPVLKVESRLDSDQQHNLQEHSTTSV", "length": 802 }, "evidence": [ { "id": "E1BBV1", "url": "https://omabrowser.org/oma/group/E1BBV1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80T69-1", "protein_name": "Lysine-specific demethylase 9", "gene_name": "Rsbn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFRSTRTTDQWRVGERLQCPAGHARAALARTADGGAVGPFKCVFVGEMAAQVGAVRVVRAVAAQEEPDKEGKEKPHVGVSPRGVKRQRRASSGGSQEKRGRPSQDPPLAPPHRRRRSRQHPGPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPTVAAPLPAPGTSALFTFSPLTVSAAGPKHKGHKERHKHHHHRGSDGDPGACVPGDLKHKDKQENGERSGGVPLIKAPKRETADENGKTQRADDFVLKKIKKKKKKKHREDMRGRRLKMYNKEVQTVCAGLTRISKEILTQGQLNSTSGVNKESFRYLKDEQLCRLNLGMQEYRVPQGVQTPFTTHQEHSIRRNFLKTGTKFSNFIHEEHQSNGGALVLHAYMDELSFLSPMEMERFSEEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKKDIETTTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKMTLPWGTLSSLQLQCRSQSDDGPIMWVRPGEQMIPTADMPKSPFKRRRSMNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHPVVETAQNTESNSNMDCGLEVDSQCVRIKTESEERCTEMQLLTTASPSFPPPSELHLQDLKTQPLPVFKVESRLDSDQQHSLQAHPSTPV", "length": 795 }, "evidence": [ { "id": "E1BBV1", "url": "https://omabrowser.org/oma/group/E1BBV1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histone H4K20 demethylase activity", "id": "GO:0035575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035575", "evidence": [ { "database": "UniProtKB", "id": "E1BBV1", "url": "https://www.uniprot.org/uniprotkb/E1BBV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BBV1", "url": "https://www.uniprot.org/uniprotkb/E1BBV1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1BBV1", "url": "https://www.uniprot.org/uniprotkb/E1BBV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "E1BBV1", "url": "https://www.uniprot.org/uniprotkb/E1BBV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BBV1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 801, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BBV1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BBV1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 }, { "start_pos": 460, "end_pos": 462 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BBW9-1", "uniprot_ac": "E1BBW9", "uniprot_id": "E1BBW9_BOVIN", "mass": { "chemical_mass": 38707.0, "monoisotopic_mass": 38707.0 }, "refseq": {}, "gene_names": [ { "name": "ADH7", "type": "recommended", "evidence": [ { "id": "E1BBW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBW9" } ] } ], "protein_names": [ { "name": "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide", "type": "synonym", "evidence": [ { "id": "E1BBW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBW9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BBW9", "url": "https://www.uniprot.org/uniprotkb/E1BBW9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADH7", "url": "https://www.uniprot.org/uniprotkb/E1BBW9", "locus": { "chromosome": "6", "start_pos": 25191445, "end_pos": 25176418, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015729", "url": "https://www.ensembl.org/id/ENSBTAG00000015729" } ] } } ], "crossref": [ { "id": "E1BBW9", "url": "https://alphafold.ebi.ac.uk/entry/E1BBW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015729", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015729", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43880:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43880:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-211935", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-211935", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-71384", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-71384", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BBW9", "url": "https://www.uniprot.org/uniprotkb/E1BBW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBW9-1", "url": "https://www.uniprot.org/uniprotkb/E1BBW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KLRAGKGVIKCKVALLWEQKKLFSTEIQVVPSKAKEVCIKMLAMGISIVSKFSVIVGHEATGVVDSIGEGVTTVKPDDKVIPHFLPQCRECNACRNPDGNPCIRTDITGHGVLADGSTRFTCKGKPVYHFLSTSTFIEYTAVDETSIAKSDDAAPPEKVCLTGCGFSTGYRATIKIGKVTPSSMCVVFGLGGVGLSVIMGCNSAGASRIVGADLNKDKFEKAMAVGATECISPKDFTKPISEVLSEMTGDTTGCSFEVIGHLETMVRAMIREGSSISQDAHVHPVLLFTGHMWKGCIFEGWKSRNYVPNLVTDFLEKKFDLDKLITHDLPFRKINERFELLNSGQRYLLFYVLTF", "length": 355, "header": "tr|E1BBW9-1|E1BBW9_BOVIN Isoform 1 of Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide OS=Bos taurus OX=9913 GN=ADH7 PE=3 SV=5 CANONICAL=E1BBW9-1" }, "isoforms": [ { "isoform_ac": "E1BBW9-1", "url": "https://www.uniprot.org/uniprotkb/E1BBW9/entry#E1BBW9-1", "sequence": { "sequence": "KLRAGKGVIKCKVALLWEQKKLFSTEIQVVPSKAKEVCIKMLAMGISIVSKFSVIVGHEATGVVDSIGEGVTTVKPDDKVIPHFLPQCRECNACRNPDGNPCIRTDITGHGVLADGSTRFTCKGKPVYHFLSTSTFIEYTAVDETSIAKSDDAAPPEKVCLTGCGFSTGYRATIKIGKVTPSSMCVVFGLGGVGLSVIMGCNSAGASRIVGADLNKDKFEKAMAVGATECISPKDFTKPISEVLSEMTGDTTGCSFEVIGHLETMVRAMIREGSSISQDAHVHPVLLFTGHMWKGCIFEGWKSRNYVPNLVTDFLEKKFDLDKLITHDLPFRKINERFELLNSGQRYLLFYVLTF", "length": 355, "header": "tr|E1BBW9-1|E1BBW9_BOVIN Isoform 1 of Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide OS=Bos taurus OX=9913 GN=ADH7 PE=3 SV=5 CANONICAL=E1BBW9-1" }, "locus": { "chromosome": "6", "start_pos": 25191442, "end_pos": 25178079, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020879.8", "url": "https://www.ensembl.org/id/ENSBTAT00000020879.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020879.8", "url": "https://www.ensembl.org/id/ENSBTAP00000020879.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": 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"https://www.reactome.org/PathwayBrowser/#R-BTA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192972", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192972", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BBY0", "url": "https://www.uniprot.org/uniprotkb/E1BBY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBY0-1", "url": "https://www.uniprot.org/uniprotkb/E1BBY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH14", "url": "https://www.uniprot.org/uniprotkb/E1BH14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH14-1", "url": "https://www.uniprot.org/uniprotkb/E1BH14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPLWLCWALWVLPLAGPGAALTEERILDSLLQQLHLSEVPIVDKATVEGLVIPAHVRAQYVALLQRGHGARSRGKRFSQNFREVVGRFLTSEASSHLLVFDMEQRLPPRSELVQAVLRLFQEPVPRAALRRHERLFPRSDRARVTVQWLHVRDDGSNRTALIDSRLVTIHESGWKALDVTEAVNFWQQLRSPRQPLLLQVLVQREHLGPLASSAHRLVRFAPQGPSSGWQGEPQLELHTLDLRDYGAQGNCDPKAPVTEGTRCCRQEMYIDLQGMKWAENWVLEPPGFLAYECVGTCQQPPESLTFKWPFLGPRQCIASEATSLPMIVSIQEGGQLQPQVVSLPNMRVQTCSCAWDGVLVPRKLEP", "length": 367, "header": "tr|E1BBY0-1|E1BBY0_BOVIN Isoform 1 of Left-right determination factor OS=Bos taurus OX=9913 GN=LEFTY2 PE=3 SV=3 CANONICAL=E1BBY0-1" }, "isoforms": [ { "isoform_ac": "E1BBY0-1", "url": "https://www.uniprot.org/uniprotkb/E1BBY0/entry#E1BBY0-1", "sequence": { "sequence": "MQPLWLCWALWVLPLAGPGAALTEERILDSLLQQLHLSEVPIVDKATVEGLVIPAHVRAQYVALLQRGHGARSRGKRFSQNFREVVGRFLTSEASSHLLVFDMEQRLPPRSELVQAVLRLFQEPVPRAALRRHERLFPRSDRARVTVQWLHVRDDGSNRTALIDSRLVTIHESGWKALDVTEAVNFWQQLRSPRQPLLLQVLVQREHLGPLASSAHRLVRFAPQGPSSGWQGEPQLELHTLDLRDYGAQGNCDPKAPVTEGTRCCRQEMYIDLQGMKWAENWVLEPPGFLAYECVGTCQQPPESLTFKWPFLGPRQCIASEATSLPMIVSIQEGGQLQPQVVSLPNMRVQTCSCAWDGVLVPRKLEP", "length": 367, "header": "tr|E1BBY0-1|E1BBY0_BOVIN Isoform 1 of Left-right determination factor OS=Bos taurus OX=9913 GN=LEFTY2 PE=3 SV=3 CANONICAL=E1BBY0-1" }, "locus": { "chromosome": "16", "start_pos": 28913354, "end_pos": 28910508, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000051964.4", "url": "https://www.ensembl.org/id/ENSBTAT00000051964.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049627.3", "url": "https://www.ensembl.org/id/ENSBTAP00000049627.3" } ] } }, { "isoform_ac": "E1BH14-1", "url": "https://www.uniprot.org/uniprotkb/E1BBY0/entry#E1BH14-1", "sequence": { "sequence": "MAASHLPRAGDTHRQTRPGAWGDEETVAGHLIRGDCWQPWGWLIKRSRCQPGASEVVGRFLTSEASSHLLVFDMEQRLPPRSELVQAVLRLFQEPVPRAALRRHERLFPRSDRARVTVQWLHVRDDGSNRTALIDSRLVTIHESGWKALDVTEAVNFWQQLRSPRQPLLLQVLVQREHLGPLASSAHRLVRFAPQGPSSGWQGEPQLELHTLDLRDYGAQGNCDPKAPVTEGTRCCRQEMYIDLQGMKWAENWVLEPPGFLAYECVGTCQQPPESLTFKWPFLGPRQCIASEATSLPMIVSIQEGGQLQPQVVSLPNMRVQTCSCAWDGVLVPRKLEP", "length": 338, "header": "tr|E1BH14-1|E1BBY0_BOVIN Computationally mapped isoform of Left-right determination factor OS=Bos taurus OX=9913 GN=LEFTY2 PE=3 SV=3 CANONICAL=E1BBY0-1" }, "locus": { "chromosome": "16", "start_pos": 28912606, "end_pos": 28910508, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003702.5", "url": "https://www.ensembl.org/id/ENSBTAT00000003702.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003702.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003702.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534018", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534018", "resource": "KEGG Pathway" }, { "id": "R-BTA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "O75610-1", "protein_name": "Left-right determination factor 1", "gene_name": "LEFTY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPLWLCWALWVLPLASPGAALTGEQLLGSLLRQLQLKEVPTLDRADMEELVIPTHVRAQYVALLQRSHGDRSRGKRFSQSFREVAGRFLALEASTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPKAALHRHGRLSPRSARARVTVEWLRVRDDGSNRTSLIDSRLVSVHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPLASGAHKLVRFASQGAPAGLGEPQLELHTLDLGDYGAQGDCDPEAPMTEGTRCCRQEMYIDLQGMKWAENWVLEPPGFLAYECVGTCRQPPEALAFKWPFLGPRQCIASETDSLPMIVSIKEGGRTRPQVVSLPNMRVQKCSCASDGALVPRRLQP", "length": 366 }, "evidence": [ { "id": "E1BBY0", "url": "https://omabrowser.org/oma/group/E1BBY0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P57785-1", "protein_name": "Left-right determination factor 2", "gene_name": "Lefty2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSLWLCWALWVLPLAGPGAAMTEEQVLSSLLQQLQLSQAPTLDSADVEEMAIPTHVRSQYVALLQGSHADRSRGKRFSQNFREVAGRFLMSETSTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPRTALRRFERLSPHSARARVTIEWLRVREDGSNRTALIDSRLVSIHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPGTWSAHKLVRFAAQGTPDGKGQGEPQLELHTLDLKDYGAQGNCDPEVPVTEGTRCCRQEMYLDLQGMKWAENWILEPPGFLTYECVGSCLQLPESLTIGWPFLGPRQCVASEMTSLPMIVSVKEGGRTRPQVVSLPNMRVQTCSCASDGALIPRGIDL", "length": 368 }, "evidence": [ { "id": "E1BBY0", "url": "https://omabrowser.org/oma/group/E1BBY0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5UCE3-1", "protein_name": "Left-right determination factor", "gene_name": "Lefty2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQSLWLCWTLCVLPLAGPGAAVTEEQVLSSLLKQLQLSQAPVLDRVDVEGMAIPTHVSSQYVALLQGSHADRSRGKRFSQNFREVAGRFLVSETSSHLLVFGMEQRLPPNSELVQAMLRLFQEPVPRTALRRLERLPPHSAQARVTIEWLRVREDGSNRTALIDSRLVSIYESGWKVFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPGTWSAHKLVRFAAQGTPDGKGEPQLELHTLDLKDYGAQGNCDPEAPVTEGTRCCRKEMYLDLQGMKWAENWILEPPGFLIYECVGSCRQLPESLTIGWPFLGPRQCVASEMTSLPMIVSIKEDGKTRPQVVSLPNMRVQTCSCASDGALIPRGIDL", "length": 366 }, "evidence": [ { "id": "E1BBY0", "url": "https://omabrowser.org/oma/group/E1BBY0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BBY0", "url": "https://www.uniprot.org/uniprotkb/E1BBY0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "E1BBY0", "url": "https://www.uniprot.org/uniprotkb/E1BBY0" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor binding", "id": "GO:0005160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005160", "evidence": [ { "database": "UniProtKB", "id": "E1BBY0", "url": "https://www.uniprot.org/uniprotkb/E1BBY0" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "E1BBY0", "url": "https://www.uniprot.org/uniprotkb/E1BBY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "E1BBY0", "url": "https://www.uniprot.org/uniprotkb/E1BBY0" } ], "pmid": "" }, { "name": "anterior/posterior axis specification", "id": "GO:0009948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009948", "evidence": [ { "database": "UniProtKB", "id": "E1BBY0", "url": "https://www.uniprot.org/uniprotkb/E1BBY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BBY0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 367, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BBY0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BBY0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BBY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY0" }, { "id": "PS51362", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51362" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TGF-beta family profile", "eco_id": "ECO_0000259", "start_pos": 241, "end_pos": 355, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BBY4-1", "uniprot_ac": "E1BBY4", "uniprot_id": "E1BBY4_BOVIN", "mass": { "chemical_mass": 34243.0, "monoisotopic_mass": 34243.0 }, "refseq": { "ac": "NP_001377266", "name": "olfactory receptor family 8 subfamily B member 4", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377266" }, "gene_names": [ { "name": "OR8B4", "type": "recommended", "evidence": [ { "id": "E1BBY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY4" } ] }, { "name": "OR8B4", "type": "synonym", "evidence": [ { "id": "NP_001377266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377266" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BBY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 8 subfamily B member 4", "type": "synonym", "evidence": [ { "id": "NP_001377266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377266" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377266", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377266" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BBY4", "url": "https://www.uniprot.org/uniprotkb/E1BBY4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BBY4", "url": "https://www.uniprot.org/uniprotkb/E1BBY4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8B4", "url": "https://www.uniprot.org/uniprotkb/E1BBY4", "locus": { "chromosome": "29", "start_pos": 27789906, "end_pos": 27790835, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000033480", "url": "https://www.ensembl.org/id/ENSBTAG00000033480" } ] } } ], "crossref": [ { "id": "E1BBY4", "url": "https://alphafold.ebi.ac.uk/entry/E1BBY4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000033480", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000033480", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15405", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15405", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "782723", "url": "https://www.ncbi.nlm.nih.gov/gene/782723", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:782723", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782723", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDQGKFA", "url": "https://omabrowser.org/oma/group/MDQGKFA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BBY4", "url": "https://www.orthodb.org/?gene=E1BBY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377266", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377266", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BBY4", "url": "https://www.uniprot.org/uniprotkb/E1BBY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBY4-1", "url": "https://www.uniprot.org/uniprotkb/E1BBY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALVNSSSLTEFILVGLSERSELQLPLFLLFLGIYVSTVVGNLGLITLIAMNSSLHTPMYFFLFNLSFIDFCYSCVFTPKMLIDFISENIISYVGCMTQLFFFCFFVNSECYVLVSMAYDRFVAICHPLLYTVTMSPQVCSLMMLGSYMIGFAGAMAHTGSMLRLSFCDSNIIHHYLCEVLPLLQLSCTSTHINELVFFIVVGGVITISSISIFTSYALILSSILRIPSAEGRSKAFSTCGSHVVAVALFFGSGAFTYLTTSFPGSKDQGKFASVFYTNVVPMLNPLIYSLRNKDVKLALRKTLKTVLF", "length": 309, "header": "tr|E1BBY4-1|E1BBY4_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR8B4 PE=3 SV=3 CANONICAL=E1BBY4-1" }, "isoforms": [ { "isoform_ac": "E1BBY4-1", "url": "https://www.uniprot.org/uniprotkb/E1BBY4/entry#E1BBY4-1", "sequence": { "sequence": "MALVNSSSLTEFILVGLSERSELQLPLFLLFLGIYVSTVVGNLGLITLIAMNSSLHTPMYFFLFNLSFIDFCYSCVFTPKMLIDFISENIISYVGCMTQLFFFCFFVNSECYVLVSMAYDRFVAICHPLLYTVTMSPQVCSLMMLGSYMIGFAGAMAHTGSMLRLSFCDSNIIHHYLCEVLPLLQLSCTSTHINELVFFIVVGGVITISSISIFTSYALILSSILRIPSAEGRSKAFSTCGSHVVAVALFFGSGAFTYLTTSFPGSKDQGKFASVFYTNVVPMLNPLIYSLRNKDVKLALRKTLKTVLF", "length": 309, "header": "tr|E1BBY4-1|E1BBY4_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR8B4 PE=3 SV=3 CANONICAL=E1BBY4-1" }, "locus": { "chromosome": "29", "start_pos": 27790835, "end_pos": 27789909, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006740.6", "url": "https://www.ensembl.org/id/ENSBTAT00000006740.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044805.4", "url": "https://www.ensembl.org/id/ENSBTAP00000044805.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:782723", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782723", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0QX44-1", "protein_name": "Olfactory receptor", "gene_name": "OR8B4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLRNSSLVTKFILVGLSQQKELQLPLFLLFLGIYVLTVVGNLGLITLIGLNTSLHTPMYFFLFNLSFIDLCYSCVFTPKMLNDFVSENIISYVGCMTQLFFFCFFVNSECYVLVSMAYDRYVAICNPLLYMVTMSPQICSLLMVGSYVIGFAGAMAHAGGMLRLTFCDSNIIDHYLCEVLPLLQLSCTSTHVNELVFFIAVGVVITLSSISIFISYTLILSNIFRIPSAEGRSKAFGTCGSHIVAVVLFFGSGAFTYLTNSFSGSMDQGKFASVFYTNVIPMLNPLIYSLRNKDVKLAEESALLMILFVSIIYW", "length": 315 }, "evidence": [ { "id": "E1BBY4", "url": "https://omabrowser.org/oma/group/E1BBY4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q96RC9-1", "protein_name": "Olfactory receptor 8B4", "gene_name": "OR8B4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLRNSSSVTEFILVGLSEQPELQLPLFLLFLGIYVFTVVGNLGLITLIGINPSLHTPMYFFLFNLSFIDLCYSCVFTPKMLNDFVSESIISYVGCMTQLFFFCFFVNSECYVLVSMAYDRYVAICNPLLYMVTMSPRVCFLLMFGSYVVGFAGAMAHTGSMLRLTFCDSNVIDHYLCDVLPLLQLSCTSTHVSELVFFIVVGVITMLSSISIVISYALILSNILCIPSAEGRSKAFSTWGSHIIAVALFFGSGTFTYLTTSFPGSMNHGRFASVFYTNVVPMLNPSIYSLRNKDDKLALGKTLKRVLF", "length": 309 }, "evidence": [ { "id": "E1BBY4", "url": "https://omabrowser.org/oma/group/E1BBY4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BBY4", "url": "https://www.uniprot.org/uniprotkb/E1BBY4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "E1BBY4", "url": "https://www.uniprot.org/uniprotkb/E1BBY4" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "E1BBY4", "url": "https://www.uniprot.org/uniprotkb/E1BBY4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BBY4", "url": "https://www.uniprot.org/uniprotkb/E1BBY4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "E1BBY4", "url": "https://www.uniprot.org/uniprotkb/E1BBY4" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "E1BBY4", "url": "https://www.uniprot.org/uniprotkb/E1BBY4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BBY4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BBY4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BBY4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BBY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 52, "end_pos": 54 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BC09-1", "uniprot_ac": "E1BC09", "uniprot_id": "E1BC09_BOVIN", "mass": { "chemical_mass": 91812.0, "monoisotopic_mass": 91812.0 }, "refseq": {}, "gene_names": [ { "name": "AOC2", "type": "recommended", "evidence": [ { "id": "E1BC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC09" } ] } ], "protein_names": [ { "name": "Amine oxidase", "type": "recommended", "evidence": [ { "id": "E1BC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC09/entry#names_and_taxonomy" } ] }, { "name": "1.4.3.-", "type": "synonym", "evidence": [ { "id": "E1BC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC09/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Has a preference for 2-phenylethylamine, tryptamine and tyramine. Could also act on methylamine and benzylamine but much less efficiently.", "evidence": [ { "database": "UniProtKB", "id": "E1BC09", "url": "https://www.uniprot.org/uniprotkb/E1BC09#function" }, { "database": "UniProtKB", "id": "ARBA00057726", "url": "https://www.uniprot.org/uniprotkb/ARBA00057726#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BC09", "url": "https://www.uniprot.org/uniprotkb/E1BC09" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AOC2", "url": "https://www.uniprot.org/uniprotkb/E1BC09", "locus": { "chromosome": "19", "start_pos": 42872439, "end_pos": 42866905, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030334", "url": "https://www.ensembl.org/id/ENSBTAG00000030334" } ] } } ], "crossref": [ { "id": "E1BC09", "url": "https://alphafold.ebi.ac.uk/entry/E1BC09", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000030334", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030334", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015798", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015798", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015802", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015802", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HFTRAED", "url": "https://omabrowser.org/oma/group/HFTRAED/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10638", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10638", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10638:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10638:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02728", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02728", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-211945", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-211945", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "30591", "url": "https://www.rhea-db.org/rhea/30591", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "59416", "url": "https://www.rhea-db.org/rhea/59416", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BC09", "url": "https://www.uniprot.org/uniprotkb/E1BC09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BC09-1", "url": "https://www.uniprot.org/uniprotkb/E1BC09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQGDARGSRTLSQTTEQKIGAELYKSRSEISRPTHRVEFSLFLSILLNINPDLMSVTGRSSWWDSQLSAFTMNLKVVLVFLALSLITIFALAYVLLTSRGGSSLPPRCPSVSPRAQPWTHPGQSQLFADLSREELMAVMSFLTQKLGPDLADAAQARPSDNCIFSVELQLPPKAAALAHLDRGRPPPAREALAIVFFGRQPQPNVTELVVGPLPQPSYMRDVTVERHGGPLPYHRRPVLATESAQMWMHLKKVEFPKAPVFLASVFNYNGSTLAALHATPRGLRSGDRATWIALYHNISGVGIFLHPVGLELLLDHRALDPAHWAVQQVFYLGHYYSDLGQLEWEFKAGRLDVVRVPLPLPDGASSLRSRVSPGPLPPLEFSPQGSRYSVQGHLVESFLWTFTFGHGAFSGMRIFDVRFKGERVAYEVSVQECLSVYGADSPKTMMTRYLDSSYGLGRHSRGLVRGVDCPYQSTMVDTHVLVGQGAVQLLPGAVCVFEEAQGLPLRRHHNQLQSHFYGGLAGSALVVRSVSSVGNYDYIWDFVLHPNGALEGRVHATGYINTAFLSGGEESLLFGNRVGERVLGAVHTHAFHFKLDLDVAGLKNWVVAEDVVFKPVAAPWSPEHQLQRPQLTRQVLGREDLTAFFLGSPLPRYLYLASNQTNAWGHQRGYRIQIHSPLGIHMPLDSTMERALSWGRYQLAVTRRKEEESQSSSIYYQNDIWTATAAFADFINNETLLGEDLVAWVTTSFLHIPHAEDVPNTVTLGNRVGFLLRPYNFFDEDPSIFSPGSVYFEKGQDAGLCSVNHVACIPHLAACVPDLPPFSYQDL", "length": 828, "header": "tr|E1BC09-1|E1BC09_BOVIN Isoform 1 of Amine oxidase OS=Bos taurus OX=9913 GN=AOC2 PE=3 SV=2 CANONICAL=E1BC09-1" }, "isoforms": [ { "isoform_ac": "E1BC09-1", "url": "https://www.uniprot.org/uniprotkb/E1BC09/entry#E1BC09-1", "sequence": { "sequence": "MGQGDARGSRTLSQTTEQKIGAELYKSRSEISRPTHRVEFSLFLSILLNINPDLMSVTGRSSWWDSQLSAFTMNLKVVLVFLALSLITIFALAYVLLTSRGGSSLPPRCPSVSPRAQPWTHPGQSQLFADLSREELMAVMSFLTQKLGPDLADAAQARPSDNCIFSVELQLPPKAAALAHLDRGRPPPAREALAIVFFGRQPQPNVTELVVGPLPQPSYMRDVTVERHGGPLPYHRRPVLATESAQMWMHLKKVEFPKAPVFLASVFNYNGSTLAALHATPRGLRSGDRATWIALYHNISGVGIFLHPVGLELLLDHRALDPAHWAVQQVFYLGHYYSDLGQLEWEFKAGRLDVVRVPLPLPDGASSLRSRVSPGPLPPLEFSPQGSRYSVQGHLVESFLWTFTFGHGAFSGMRIFDVRFKGERVAYEVSVQECLSVYGADSPKTMMTRYLDSSYGLGRHSRGLVRGVDCPYQSTMVDTHVLVGQGAVQLLPGAVCVFEEAQGLPLRRHHNQLQSHFYGGLAGSALVVRSVSSVGNYDYIWDFVLHPNGALEGRVHATGYINTAFLSGGEESLLFGNRVGERVLGAVHTHAFHFKLDLDVAGLKNWVVAEDVVFKPVAAPWSPEHQLQRPQLTRQVLGREDLTAFFLGSPLPRYLYLASNQTNAWGHQRGYRIQIHSPLGIHMPLDSTMERALSWGRYQLAVTRRKEEESQSSSIYYQNDIWTATAAFADFINNETLLGEDLVAWVTTSFLHIPHAEDVPNTVTLGNRVGFLLRPYNFFDEDPSIFSPGSVYFEKGQDAGLCSVNHVACIPHLAACVPDLPPFSYQDL", "length": 828, "header": "tr|E1BC09-1|E1BC09_BOVIN Isoform 1 of Amine oxidase OS=Bos taurus OX=9913 GN=AOC2 PE=3 SV=2 CANONICAL=E1BC09-1" }, "locus": { "chromosome": "19", "start_pos": 42872044, "end_pos": 42867104, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042833.5", "url": "https://www.ensembl.org/id/ENSBTAT00000042833.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040444.4", "url": "https://www.ensembl.org/id/ENSBTAP00000040444.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-211945", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-211945", "resource": "Reactome", "description": "Phase I - Functionalization of compounds" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S1G7-1", "protein_name": "Amine oxidase", "gene_name": "AOC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLKVVLVLLALSLITIFALAYVLLTSQGGSSQPPHCPSVSHSAQPWTHPGQSQLFADLSREELTAVMNFLTQKLGPGLGEAAQARPADNCIFSVELQLPPKAAALAHLDRGSPPPAREALAIIFFGGQPQPNVTELVVGPLPQPSYVRDVTVERHGGPLPYHRRPVLGNESAQMWKHLKEVELPKAPVFLASVCSYNGSNLAALHATPRGLRSGDRATWMALYHNISGVGIFLHPVGLELLLDHRALDPVRWAVRQVFYLGRYYADLGQLEWEFKAGRLEVVRVPLPLPDGASSLRSRISPGPLPPLQFSPQGSRYSVQGHLVASSLWTFTFGHGVFSGLRIFDVRFKGERVAYEVSVQECVSIYGADSPKTMMTRYLDSSYGLGRHSRGLVRGVDCPYQSTMVDIHVLVGRGAVQLLPGAVCVFEEAQGVPLRRHHNHLQSHFYGGLAGSALVVRSVSSVGNYDYIWDFVLHPNGALEGRVRATGYINTAFLSGEESLLFGNRVGERVLGAVHTHAFHFKLDLDVAGLKNWVVAEDVVFKPVAAPWSPEHQLHRPELTRQVLRREDLTAFLWGTPLPRYLYLASNQTNAWGHQRGYRIQIHSPLGIHMPLDSDMERALSWGRYQLVVTRRKEEESQSSSIYYQNDIWTSATAFADFINNETLLGEDLVAWVTASFLHIPHAEDVPNTVTLGNRVGFLLRPYNFFDEDPSVFSPDSVYFEKGQDAGRCSVNHVACIPHLAACVPDLPPFSYRDL", "length": 755 }, "evidence": [ { "id": "E1BC09", "url": "https://omabrowser.org/oma/group/E1BC09/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75106-1", "protein_name": "Amine oxidase [copper-containing] 2", "gene_name": "AOC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHLKIVLAFLALSLITIFALAYVLLTSPGGSSQPPHCPSVSHRAQPWPHPGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQAQPSDNCIFSVELQLPPKAAALAHLDRGSPPPAREALAIVLFGGQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLRAEFTQMWRHLKEVELPKAPIFLSSTFNYNGSTLAAVHATPRGLRSGDRATWMALYHNISGVGLFLHPVGLELLLDHRALDPAHWTVQQVFYLGHYYADLGQLEREFKSGRLEVVRVPLPPPNGASSLRSRNSPGPLPPLQFSPQGSQYSVQGNLVVSSLWSFTFGHGVFSGLRIFDVRFQGERIAYEVSVQECVSIYGADSPKTMLTRYLDSSFGLGRNSRGLVRGVDCPYQATMVDIHILVGKGAVQLLPGAVCVFEEAQGLPLRRHHNYLQNHFYGGLASSALVVRSVSSVGNYDYIWDFVLYPNGALEGRVHATGYINTAFLKGGEEGLLFGNRVGERVLGTVHTHAFHFKLDLDVAGLKNWVVAEDVVFKPVAAPWNPEHWLQRPQLTRQVLGKEDLTAFSLGSPLPRYLYLASNQTNAWGHQRGYRIQIHSPLGIHIPLESDMERALSWGRYQLVVTQRKEEESQSSSIYHQNDIWTPTVTFADFINNETLLGEDLVAWVTASFLHIPHAEDIPNTVTLGNRVGFLLRPYNFFDEDPSIFSPGSVYFEKGQDAGLCSINPVACLPDLAACVPDLPPFSYHGF", "length": 756 }, "evidence": [ { "id": "E1BC09", "url": "https://omabrowser.org/oma/group/E1BC09/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q812C9-1", "protein_name": "Amine oxidase [copper-containing] 2", "gene_name": "Aoc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLKVLLLLLGLSFLTVFALVYVLLTRQGSFSQSPRCPSIPPRIHPWTHPSQSQLFADLTPEELTAVMSFLTKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPPVREALAIIFFGGQPKPNVSELVVGPLPHPSYMRDVTVERHGGPLPYYRRPMQKTEFVQIWRHLKEVELPKAPTFLASVLNYNGSTLAPLHSTASGFHAGDRATWIALYHNISGLGVFLHPVGLELLLDHGALDPADWVVQQVFYLGHYYADLAQLEWEFKVGRLEVIRVPLPTPGGASSLRPRVTPDPPLPPLQFSLQGPQYNIQGNSVTSPLWTFTFGHGVFSGLRIFDIRFKGERVAYEVSVQECLTVYGADSPKTMTIRYLDSSYGLGLNSRALVRGVDCPYQATMVDIHVLVGTGSVQLLPGAVCVFEEAQGLPLRRHHNGIGGHFYGGLASSSLVVRSVSSVGNYDYIWDFMLHPTGALEARVHATGYINTAFMSGGAESLLFGNRVGERVLGAVHTHAFHFKLDLDVAGLKNWVIAEDAVFKPVAAPWNPELQLQRPQLTRQVLSREDLAAFPWGSPLPRYLYLATNQTNAWGHQRGYRIQIHSPPGVHVPLESSEERALSWGRYQLVVTQRKEAEPHSSSIYYQNDMRSPATVFADFINNETLLGEDLVAWVTASFLHIPHAEDIPNTVTVGNRVGFLLRPYNFFNEDPSIFSPGSVYFERDQDAGLCSINPVACTQQLADCVPNLPSFSYEGL", "length": 757 }, "evidence": [ { "id": "E1BC09", "url": "https://omabrowser.org/oma/group/E1BC09/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BC09", "url": "https://www.uniprot.org/uniprotkb/E1BC09" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "E1BC09", "url": "https://www.uniprot.org/uniprotkb/E1BC09" } ], "pmid": "" }, { "name": "primary methylamine oxidase activity", "id": "GO:0008131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008131", "evidence": [ { "database": "UniProtKB", "id": "E1BC09", "url": "https://www.uniprot.org/uniprotkb/E1BC09" } ], "pmid": "" }, { "name": "quinone binding", "id": "GO:0048038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048038", "evidence": [ { "database": "UniProtKB", "id": "E1BC09", "url": "https://www.uniprot.org/uniprotkb/E1BC09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "catecholamine metabolic process", "id": "GO:0006584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006584", "evidence": [ { "database": "UniProtKB", "id": "E1BC09", "url": "https://www.uniprot.org/uniprotkb/E1BC09" } ], "pmid": "" }, { "name": "amine metabolic process", "id": "GO:0009308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009308", "evidence": [ { "database": "UniProtKB", "id": "E1BC09", "url": "https://www.uniprot.org/uniprotkb/E1BC09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 660, "end_pos": 662, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "30591", "name": "", "equation": "tyramine + O2 + H2O = (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9RYG5-1", "A0A140T837-1", "P21398-1", "P56560-1", "E1BC09-1" ], "evidence": [ { "id": "30591", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30591" } ] }, { "id": "59416", "name": "", "equation": "tryptamine + O2 + H2O = indole-3-acetaldehyde + H2O2 + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9RYG5-1", "P21398-1", "E1BC09-1" ], "evidence": [ { "id": "59416", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59416" } ] }, { "id": "R-BTA-5696146", "name": "AOC2 deaminates TYR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-5696181" ], "output_participant_list": [ "R-ALL-5696178" ], "enzyme_list": [ "E1BC09-1" ], "evidence": [ { "id": "R-BTA-5696146", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5696146" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5696178", "participant_name": "4HPAA [extracellular region]", "crossref": [ { "id": "6635", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "C03765", "database": "COMPOUND", "url": "" }, { "id": "HMDB0003767", "database": "HMDB Metabolite", "url": "" }, { "id": "15621", "database": "ChEBI", "url": "" }, { "id": "ZINC000000901834", "database": "ZINC", "url": "" }, { "id": "8143296", "database": "PubChem Substance", "url": "" } ] }, { "participant_id": "R-ALL-5696181", "participant_name": "TYR [extracellular region]", "crossref": [ { "id": "15760", "database": "ChEBI", "url": "" }, { "id": "8143353", "database": "PubChem Substance", "url": "" }, { "id": "C00483", "database": "COMPOUND", "url": "" }, { "id": "2150", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000000002233", "database": "ZINC", "url": "" }, { "id": "HMDB0000306", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T837", "gene_name": "MAOB", "activity": [ { "ec_number": "1.4.3.-", "activity": "", "evidence": [ { "id": "A0A140T837", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T837" } ] } ] }, { "uniprot_ac": "A0AAA9RYG5", "gene_name": "MAOA", "activity": [ { "ec_number": "1.4.3.-", "activity": "", "evidence": [ { "id": "A0AAA9RYG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYG5" } ] } ] }, { "uniprot_ac": "E1BC09", "gene_name": "AOC2", "activity": [ { "ec_number": "1.4.3.-", "activity": "", "evidence": [ { "id": "E1BC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC09" } ] } ] }, { "uniprot_ac": "P21398", "gene_name": "MAOA", "activity": [ { "ec_number": "1.4.3.4", "activity": "a secondary aliphatic amine + O2 + H2O = a primary amine + an aldehyde + H2O2.", "evidence": [ { "id": "P21398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21398" } ] }, { "ec_number": "1.4.3.21", "activity": "a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+).", "evidence": [ { "id": "P21398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21398" } ] }, { "ec_number": "1.4.3.4", "activity": "", "evidence": [ { "id": "P21398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21398" } ] }, { "ec_number": "1.4.3.21", "activity": "", "evidence": [ { "id": "P21398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21398" } ] } ] }, { "uniprot_ac": "P56560", "gene_name": "MAOB", "activity": [ { "ec_number": "1.4.3.4", "activity": "a secondary aliphatic amine + O2 + H2O = a primary amine + an aldehyde + H2O2.", "evidence": [ { "id": "P56560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56560" } ] }, { "ec_number": "1.4.3.21", "activity": "a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+).", "evidence": [ { "id": "P56560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56560" } ] }, { "ec_number": "1.4.3.4", "activity": "", "evidence": [ { "id": "P56560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56560" } ] }, { "ec_number": "1.4.3.21", "activity": "", "evidence": [ { "id": "P56560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56560" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BC09-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 828, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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}, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BC49", "url": "https://www.uniprot.org/uniprotkb/E1BC49" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BC49", "url": "https://www.uniprot.org/uniprotkb/E1BC49" } ], "pmid": "" }, { "name": "phosphatidylcholine lysophospholipase activity", "id": "GO:0004622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004622", "evidence": [ { "database": "UniProtKB", "id": "E1BC49", "url": "https://www.uniprot.org/uniprotkb/E1BC49" } ], "pmid": "" }, { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "E1BC49", "url": 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"evidence": [ { "database": "UniProtKB", "id": "E1BC49", "url": "https://www.uniprot.org/uniprotkb/E1BC49" } ], "pmid": "" }, { "name": "prostaglandin biosynthetic process", "id": "GO:0001516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001516", "evidence": [ { "database": "UniProtKB", "id": "E1BC49", "url": "https://www.uniprot.org/uniprotkb/E1BC49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15177", "name": "", "equation": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9T0P5-1", "Q8WMP9-1", "A4IFJ5-1", "A0A3Q1LV96-1", "Q3SZ79-1", "G3X6Z1-1", "F1MNU5-1", "E1BB89-1", "A0AAA9RYE9-1", "E1BC49-1", "F1MG30-1", "F1MGH2-1", "F1MFC1-1" ], "evidence": [ { "id": "15177", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15177" } ] }, { "id": "15801", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MFC1-1", "F1MG30-1", "E1BB89-1", "E1BC49-1", "Q8WMP9-1", "P00593-1", "A4IFJ5-1", "A0A3Q1LV96-1", "E1BLF3-1", "O77834-1", "E1B9V3-1", "E1BEG8-1", "A0AAA9T9W1-1", "Q56JZ2-1", "G3N3U6-1", "Q0VC00-1", "Q1JPB9-1", "Q2KI18-1", "A0A3Q1LNM7-1", "F1MNU5-1", "F1MSG5-1", "F6RTH3-1", "A0AAA9TQC6-1", "G5E5T0-1", "A0AAA9RYE9-1", "A0ABI0P1I9-1" ], "evidence": [ { "id": "15801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15801" } ] }, { "id": "36231", "name": "", "equation": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "P79106-1", "A0A3Q1LV96-1", "F1MNU5-1", "E1BB89-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "36231", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36231" } ] }, { "id": "40427", "name": "", "equation": "1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BC49-1", "F1MFC1-1", "F1MG30-1", "A4IFJ5-1", "P00593-1", "Q1JPB9-1", "F1MNU5-1", "E1BB89-1", "A0AAA9RYE9-1" ], "evidence": [ { "id": "40427", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40427" } ] }, { "id": "40451", "name": "", "equation": "1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "40451", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40451" } ] }, { "id": "40519", "name": "", "equation": "1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BB89-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "40519", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40519" } ] }, { "id": "40811", "name": "", "equation": "1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = (9Z,12Z)-octadecadienoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "A0A3Q1LV96-1", "E1BLF3-1", "Q56JZ2-1", "Q1JPB9-1", "F1MNU5-1", "E1BB89-1", "A0AAA9RYE9-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "40811", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40811" } ] }, { "id": "41067", "name": "", "equation": "1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BB89-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "41067", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41067" } ] }, { "id": "41071", "name": "", "equation": "1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "41071", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41071" } ] }, { "id": "41075", "name": "", "equation": "1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "41075", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41075" } ] }, { "id": "41087", "name": "", "equation": "1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "41087", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41087" } ] }, { "id": "41099", "name": "", "equation": "1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "41099", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41099" } ] }, { "id": "41123", "name": "", "equation": "1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "41123", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41123" } ] }, { "id": "41271", "name": "", "equation": "1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 2-O-hexadecyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "41271", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41271" } ] }, { "id": "41307", "name": "", "equation": "1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + H2O = (9Z,12Z,15Z)-octadecatrienoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "41307", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41307" } ] }, { "id": "53688", "name": "", "equation": "2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + sn-glycerol 3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "53688", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53688" } ] }, { "id": "53692", "name": "", "equation": "2-(prostaglandin E2)-sn-glycero-3-phosphocholine + H2O = prostaglandin E2 + sn-glycerol 3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "53692", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53692" } ] }, { "id": "53696", "name": "", "equation": "2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + sn-glycerol 3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "53696", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53696" } ] }, { "id": "53700", "name": "", "equation": "2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O = (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + sn-glycerol 3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "53700", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53700" } ] }, { "id": "53704", "name": "", "equation": "2-(prostaglandin E2)-sn-glycero-3-phosphoethanolamine + H2O = sn-glycero-3-phosphoethanolamine + prostaglandin E2 + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFJ5-1", "F1MNU5-1", "E1BC49-1", "F1MG30-1", "F1MFC1-1" ], "evidence": [ { "id": "53704", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53704" } ] }, { "id": "R-BTA-1482604", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-1524103" ], "enzyme_list": [ "F1MG30-1", "E1BC49-1" ], "evidence": [ { "id": "R-BTA-1482604", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482604" } ] }, { "id": "R-BTA-1482612", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-975614" ], "output_participant_list": [ "R-ALL-1498750" ], "enzyme_list": [ "Q9GL30-1", "F1MNU5-1", "F1MG30-1", "F1MFC1-1", "E1BC49-1" ], "evidence": [ { "id": "R-BTA-1482612", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482612" } ] }, { "id": "R-BTA-1482656", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MG30-1", "E1BC49-1" ], "evidence": [ { "id": "R-BTA-1482656", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482656" } ] }, { "id": "R-BTA-1482685", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-1524028" ], "output_participant_list": [], "enzyme_list": [ "Q9GL30-1", "F1MNU5-1", "F1MG30-1", "F1MFC1-1", "E1BC49-1" ], "evidence": [ { "id": "R-BTA-1482685", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482685" } ] }, { "id": "R-BTA-1482745", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-1524042" ], "output_participant_list": [ "R-ALL-1524027", "R-ALL-1524085" ], "enzyme_list": [ "F1MNU5-1", "F1MG30-1", "E1BC49-1" ], "evidence": [ { "id": "R-BTA-1482745", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482745" } ] }, { "id": "R-BTA-1482771", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MNU5-1", "F1MG30-1", "F1MFC1-1", "E1BC49-1" ], "evidence": [ { "id": "R-BTA-1482771", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482771" } ] }, { "id": "R-BTA-1482847", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-1524047" ], "enzyme_list": [ "F1MNU5-1", "F1MG30-1", "E1BC49-1" ], "evidence": [ { "id": "R-BTA-1482847", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482847" } ] }, { "id": "R-BTA-1482856", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9GL30-1", "F1MNU5-1", "F1MG30-1", "E1BB89-1", "E1BC49-1" ], "evidence": [ { "id": "R-BTA-1482856", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482856" } ] }, { "id": "R-BTA-1482862", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MNU5-1", "F1MG30-1", "F1MFC1-1", "E1BC49-1" ], "evidence": [ { "id": "R-BTA-1482862", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482862" } ] }, { "id": "R-BTA-1482884", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9GL30-1", "F1MNU5-1", "F1MG30-1", "F1MFC1-1", "E1BB89-1", "E1BC49-1" ], "evidence": [ { "id": "R-BTA-1482884", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482884" } ] }, { "id": "R-BTA-1482900", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MG30-1", "E1BC49-1" ], "evidence": [ { "id": "R-BTA-1482900", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482900" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1498750", "participant_name": "GPCho [cytosol]", "crossref": [ { "id": "ZINC000001532714", "database": "ZINC", "url": "" }, { "id": "16870", "database": "ChEBI", "url": "" }, { "id": "HMDB0000086", "database": "HMDB Metabolite", "url": "" }, { "id": "C00670", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-1524027", "participant_name": "1-acyl LPG [mitochondrial inner membrane]", "crossref": [ { "id": "62747", "database": "ChEBI", "url": "" }, { "id": "C18126", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-1524028", "participant_name": "1-acyl LPC [endoplasmic reticulum membrane]", "crossref": [ { "id": "17504", "database": "ChEBI", "url": "" }, { "id": "C04230", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-1524042", "participant_name": "PG [mitochondrial inner membrane]", "crossref": [ { "id": "64716", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1524047", "participant_name": "2-acyl LPG [mitochondrial inner membrane]", "crossref": [ { "id": "27923", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1524085", "participant_name": "LCFA(-) [mitochondrial inner membrane]", "crossref": [ { "id": "C00060", "database": "COMPOUND", "url": "" }, { "id": "57560", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1524103", "participant_name": "LCFA(-) [mitochondrial outer membrane]", "crossref": [ { "id": "57560", "database": "ChEBI", "url": "" }, { "id": "C00060", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-975614", "participant_name": "2-acyl LPC [endoplasmic reticulum membrane]", "crossref": [ { "id": "16728", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LNM7", "gene_name": "PLA2G2F", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LNM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNM7" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A3Q1LNM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNM7" } ] } ] }, { "uniprot_ac": "A0A3Q1LV96", "gene_name": "PLB1", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] } ] }, { "uniprot_ac": "A0AAA9RYE9", "gene_name": "PNPLA8", "activity": [ { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9RYE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYE9" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0AAA9RYE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYE9" } ] } ] }, { "uniprot_ac": "A0AAA9T0P5", "gene_name": "PNPLA6", "activity": [ { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9T0P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0P5" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0AAA9T0P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0P5" } ] } ] }, { "uniprot_ac": "A0AAA9T9W1", "gene_name": "PLA2G2C", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9T9W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9W1" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0AAA9T9W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9W1" } ] } ] }, { "uniprot_ac": "A0AAA9TQC6", "gene_name": "LOC613966", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9TQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQC6" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0AAA9TQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQC6" } ] } ] }, { "uniprot_ac": "A0ABI0P1I9", "gene_name": "", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0ABI0P1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I9" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0ABI0P1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I9" } ] } ] }, { "uniprot_ac": "A4IFJ5", "gene_name": "PLA2G4A", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A4IFJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFJ5" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A4IFJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFJ5" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A4IFJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFJ5" } ] } ] }, { "uniprot_ac": "E1B9V3", "gene_name": "LOC112443425", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1B9V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9V3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1B9V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9V3" } ] } ] }, { "uniprot_ac": "E1BB89", "gene_name": "PLA2G6", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] } ] }, { "uniprot_ac": "E1BC49", "gene_name": "PLA2G4B", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BC49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC49" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1BC49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC49" } ] } ] }, { "uniprot_ac": "E1BEG8", "gene_name": "PLA2G5", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BEG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG8" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1BEG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG8" } ] } ] }, { "uniprot_ac": "E1BLF3", "gene_name": "LOC615045", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BLF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLF3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1BLF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLF3" } ] } ] }, { "uniprot_ac": "F1MFC1", "gene_name": "PLA2G4E", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "F1MFC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFC1" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "F1MFC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFC1" } ] } ] }, { "uniprot_ac": "F1MG30", "gene_name": "PLA2G4D", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "F1MG30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG30" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "F1MG30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG30" } ] } ] }, { "uniprot_ac": "F1MGH2", "gene_name": "ASPG", "activity": [ { "ec_number": "3.5.1.1", "activity": "L-asparagine + H2O = L-aspartate + NH4(+).", "evidence": [ { "id": "F1MGH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGH2" } ] }, { "ec_number": "3.5.1.1", "activity": "", "evidence": [ { "id": "F1MGH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGH2" } ] }, { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "F1MGH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGH2" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "F1MGH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGH2" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "F1MGH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGH2" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "F1MGH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGH2" } ] } ] }, { "uniprot_ac": "F1MNU5", "gene_name": "PLA2G4F", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "F1MNU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU5" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "F1MNU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU5" } ] } ] }, { "uniprot_ac": "F1MSG5", "gene_name": "PLA2G2E", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "F1MSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG5" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "F1MSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG5" } ] } ] }, { "uniprot_ac": "F6RTH3", "gene_name": "PLA2G2D4", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "F6RTH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTH3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "F6RTH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTH3" } ] } ] }, { "uniprot_ac": "G3N3U6", "gene_name": "PLA2G2D3", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G3N3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U6" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "G3N3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U6" } ] } ] }, { "uniprot_ac": "G3X6Z1", "gene_name": "PNPLA7", "activity": [ { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G3X6Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Z1" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "G3X6Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Z1" } ] } ] }, { "uniprot_ac": "G5E5T0", "gene_name": "PNPLA2", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] } ] }, { "uniprot_ac": "O77834", "gene_name": "PRDX6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "2.3.1.23", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] } ] }, { "uniprot_ac": "P00593", "gene_name": "PLA2G1B", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "P00593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00593" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "P00593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00593" } ] } ] }, { "uniprot_ac": "P79106", "gene_name": "PAFAH2", "activity": [ { "ec_number": "2.3.1.149", "activity": "a 1-organyl-2-lyso-sn-glycero-3-phospholipid + a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine = a 1-organyl-2-acetyl-sn-glycero-3-phospholipid + a 1-O-alkyl-sn-glycero-3-phosphocholine.", "evidence": [ { "id": "P79106", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79106" } ] }, { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "P79106", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79106" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "P79106", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79106" } ] } ] }, { "uniprot_ac": "Q0VC00", "gene_name": "ABHD3", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q0VC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC00" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q0VC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC00" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "Q0VC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC00" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "Q0VC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC00" } ] } ] }, { "uniprot_ac": "Q1JPB9", "gene_name": "PLA2G3", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q1JPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPB9" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "Q1JPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPB9" } ] } ] }, { "uniprot_ac": "Q2KI18", "gene_name": "PNPLA2", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] } ] }, { "uniprot_ac": "Q3SZ79", "gene_name": "LIPC", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q3SZ79", "database": "UniProtKB", "url": 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"evidence": [ { "database": "UniProtKB", "id": "E1BC52", "url": "https://www.uniprot.org/uniprotkb/E1BC52" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CFAP418", "url": "https://www.uniprot.org/uniprotkb/E1BC52", "locus": { "chromosome": "14", "start_pos": 69079022, "end_pos": 69055163, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000065822", "url": "https://www.ensembl.org/id/ENSBTAG00000065822" } ] } } ], "crossref": [ { "id": "E1BC52", "url": "https://alphafold.ebi.ac.uk/entry/E1BC52", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000043970", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000043970", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "614744", "url": "https://www.ncbi.nlm.nih.gov/gene/614744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029239", "url": 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"Protein Classification", "Other" ] }, { "id": "XP_002692859", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692859", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BC52", "url": "https://www.uniprot.org/uniprotkb/E1BC52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BC52-1", "url": "https://www.uniprot.org/uniprotkb/E1BC52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEDLDELLDEVESKFCRPDPLRLGTVERPRGGGGGFFGHDQNRAEAKENLRSAETFEKEDDLDSLINEIFEEPHFDKKHFKLKSKSSGNTSVRASIQGLGKSCSPVYIGGSTVPCGIGTNASPRACDHLRCTACDFWVESYDDYRWDKSCDYLFFRNNMPEFHKLKTKLVKKKGTRAYACQCSWKAVEELTDLQTDHQLRWVCGKH", "length": 207, "header": "sp|E1BC52-1|CF418_BOVIN Isoform 1 of Cilia- and flagella-associated protein 418 OS=Bos taurus OX=9913 GN=CFAP418 PE=1 SV=1 CANONICAL=E1BC52-1" }, "isoforms": [ { "isoform_ac": "E1BC52-1", "url": "https://www.uniprot.org/uniprotkb/E1BC52/entry#E1BC52-1", "sequence": { "sequence": "MAEDLDELLDEVESKFCRPDPLRLGTVERPRGGGGGFFGHDQNRAEAKENLRSAETFEKEDDLDSLINEIFEEPHFDKKHFKLKSKSSGNTSVRASIQGLGKSCSPVYIGGSTVPCGIGTNASPRACDHLRCTACDFWVESYDDYRWDKSCDYLFFRNNMPEFHKLKTKLVKKKGTRAYACQCSWKAVEELTDLQTDHQLRWVCGKH", "length": 207, "header": "sp|E1BC52-1|CF418_BOVIN Isoform 1 of Cilia- and flagella-associated protein 418 OS=Bos taurus OX=9913 GN=CFAP418 PE=1 SV=1 CANONICAL=E1BC52-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "E1BC52", "url": "https://www.uniprot.org/uniprotkb/E1BC52" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] }, { "title": "Mutations in C8orf37, encoding a ciliary protein, are associated with autosomal-recessive retinal dystrophies with early macular involvement.", "journal": "Am. J. Hum. Genet.", "date": "2012", "authors": "Estrada-Cuzcano A, Neveling K, Kohl S, Banin E, Rotenstreich Y, Sharon D, Falik-Zaccai TC, Hipp S, Roepman R, Wissinger B, Letteboer SJ, Mans DA, Blokland EA, Kwint MP, Gijsen SJ, van Huet RA, Collin RW, Scheffer H, Veltman JA, Zrenner E, den Hollander AI, Klevering BJ, Cremers FP", "evidence": [ { "database": "UniProtKB", "id": "E1BC52", "url": "https://www.uniprot.org/uniprotkb/E1BC52" } ], "reference": [ { "type": "PubMed", "id": "22177090", "url": "https://glygen.org/publication/PubMed/22177090" } ] } ], "pathway": [ { "id": "bta:614744", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614744", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BAN6-1", "protein_name": "Cilia- and flagella-associated protein 418", "gene_name": "CFAP418", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"MASQVLVYPPYIYQTQSSAFCSVKKLRVEPSSCVFQERNYPRTYVNGRNVGNSHPPTKGSAFQTKIPFNRPRGHNLSLQTSAVVIKNPAGATKVIAAQAPQTQVEAPQIGAWRHRFSFLEGPQRCGLKRKSEELDNHSSAMQIVDEVSILPAMLQTNMGNPVTVVTTTTGTKQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCRETDLSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDIVHVNTVMDLEGSDLLAEKADRREFVGLLKKMLLIDADLRITPAETLNHAFVNMKHLLDFPHSNHVKSCFHIMDICKSHPNSCDANNHNKTSLLRPVAPSSTTNLAANFTKIGTLRSQALTTSAHSVVHHGIPLQAGTAHFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQQTWSGRTQQMLIPAWQQVTPLAPATTALASEGVAGSQRLGDWGKMISHSNHYSSMMPQPLLTNQITLSAPQPISVGIAHVVWPQPATTKKNKLCQNRGILVKLMEWEPGREEINAFSWSNSLQNTNIPQSAFISPKTVTGKDVQEVSCIETQDNRNSEGEAGNCCDTSIRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSSQRHSLRECKGNLDCEACQSTLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESGCDTVDGSPTSDSSGHDSPFAESSFVEDTHQNAELVTSTDTETKPAVCTVVVPPMGLENGLNADEHMANTDSICQPLIKGRSAPGRLNQPSTVGNRQQKSTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAASAHLGGQPTLLPYPSSAPLSSAAPVAHLLASPCTSRPMLQHPTYNISHPSGIVHQVPVGINPRLLPSPTIHQTQYKPIFPPHSYIAASPAYTGFPLSPTKLSQYPYM", "length": 1217, "header": "tr|E1BC69-1|E1BC69_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=HIPK3 PE=3 SV=4 CANONICAL=E1BC69-1" }, "isoforms": [ { "isoform_ac": "E1BC69-1", "url": "https://www.uniprot.org/uniprotkb/E1BC69/entry#E1BC69-1", "sequence": { "sequence": "MASQVLVYPPYIYQTQSSAFCSVKKLRVEPSSCVFQERNYPRTYVNGRNVGNSHPPTKGSAFQTKIPFNRPRGHNLSLQTSAVVIKNPAGATKVIAAQAPQTQVEAPQIGAWRHRFSFLEGPQRCGLKRKSEELDNHSSAMQIVDEVSILPAMLQTNMGNPVTVVTTTTGTKQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCRETDLSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDIVHVNTVMDLEGSDLLAEKADRREFVGLLKKMLLIDADLRITPAETLNHAFVNMKHLLDFPHSNHVKSCFHIMDICKSHPNSCDANNHNKTSLLRPVAPSSTTNLAANFTKIGTLRSQALTTSAHSVVHHGIPLQAGTAHFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQQTWSGRTQQMLIPAWQQVTPLAPATTALASEGVAGSQRLGDWGKMISHSNHYSSMMPQPLLTNQITLSAPQPISVGIAHVVWPQPATTKKNKLCQNRGILVKLMEWEPGREEINAFSWSNSLQNTNIPQSAFISPKTVTGKDVQEVSCIETQDNRNSEGEAGNCCDTSIRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSSQRHSLRECKGNLDCEACQSTLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESGCDTVDGSPTSDSSGHDSPFAESSFVEDTHQNAELVTSTDTETKPAVCTVVVPPMGLENGLNADEHMANTDSICQPLIKGRSAPGRLNQPSTVGNRQQKSTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAASAHLGGQPTLLPYPSSAPLSSAAPVAHLLASPCTSRPMLQHPTYNISHPSGIVHQVPVGINPRLLPSPTIHQTQYKPIFPPHSYIAASPAYTGFPLSPTKLSQYPYM", "length": 1217, "header": "tr|E1BC69-1|E1BC69_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=HIPK3 PE=3 SV=4 CANONICAL=E1BC69-1" }, "locus": { "chromosome": "15", "start_pos": 63962390, "end_pos": 63908516, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039686.7", "url": "https://www.ensembl.org/id/ENSBTAT00000039686.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039475.6", "url": "https://www.ensembl.org/id/ENSBTAP00000039475.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E1BC69", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "E1BC69", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BC69", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BC69", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BC69", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BC69", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "E1BC69", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "E1BC69", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ], "pmid": "" }, { "name": "mRNA transcription", "id": "GO:0009299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009299", "evidence": [ { "database": "UniProtKB", "id": "E1BC69", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1056, "end_pos": 1058, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1100, "end_pos": 1102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1155, "end_pos": 1157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q58D94", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] } ] }, { "uniprot_ac": "Q8MIT6", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] } ] }, { "uniprot_ac": "Q95KV0", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] } ] }, { "uniprot_ac": "Q9N0P9", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] } ] }, { "uniprot_ac": "V6F977", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BC69-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1217, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BC69-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BC69" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 197, "end_pos": 525, "start_aa": "Tyr", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1056, "end_pos": 1058 }, { "start_pos": 1100, "end_pos": 1102 }, { "start_pos": 1155, "end_pos": 1157 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 581, "end_pos": 583 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BC78-1", "uniprot_ac": "E1BC78", "uniprot_id": "E1BC78_BOVIN", "mass": { "chemical_mass": 156384.0, "monoisotopic_mass": 156384.0 }, "refseq": { "ac": "NP_001092490", "name": "ATPase family AAA domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092490" }, "gene_names": [ { "name": "ATAD2", "type": "recommended", "evidence": [ { "id": "E1BC78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC78" } ] }, { "name": "ATAD2", "type": "synonym", "evidence": [ { "id": "NP_001092490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092490" } ] } ], "protein_names": [ { "name": "ATPase family AAA domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "E1BC78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC78/entry#names_and_taxonomy" } ] }, { "name": "ATPase family AAA domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001092490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092490" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BC78", "url": "https://www.uniprot.org/uniprotkb/E1BC78" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ATAD2", "url": "https://www.uniprot.org/uniprotkb/E1BC78", "locus": { "chromosome": "14", "start_pos": 16517917, "end_pos": 16454611, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002002", "url": "https://www.ensembl.org/id/ENSBTAG00000002002" } ] } } ], "crossref": [ { "id": "E1BC78", "url": "https://alphafold.ebi.ac.uk/entry/E1BC78", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002002", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002002", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05528", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05528", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19517", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19517", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "522920", "url": "https://www.ncbi.nlm.nih.gov/gene/522920", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045199", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045199", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:522920", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522920", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BC78", "url": "https://www.orthodb.org/?gene=E1BC78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23069", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23069", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23069:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23069:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8866910", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866910", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001092490", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092490", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BC78", "url": "https://www.uniprot.org/uniprotkb/E1BC78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BC78-1", "url": "https://www.uniprot.org/uniprotkb/E1BC78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVLRSSLELQSHPAASATDSLDLSSEFLSLEQIGRRRLRSAGAAEQSAVTAAAAGDGSSVKEVETYHQTRTLRSLRKNAQNSSDSSFDKNTVITEKHANGRHFTRQLARQQADKKKEECKEDKAIAVTRSLRTRSIVQKTEHLHEESGDVEVRRSCRIRSRYGSVNQSVLFDKLITNTAEAVLQKMDDMEKQRRRRMRKLEDLEVFNETEEGNLNMYTRGKQKDIQRTDEETTDNQEGSVESSEEGEDQEDEDEDDEEEEDDDDDEDEEDVEEDNQKRYYLRQRKATVYYQAPLEKPRHQRKPKIFYTGPASPARPRYRLSSAGPRSPYCKRMNRRRHAIHSSDSTSSSSSEDEQQFERRRKRSRNRAINRCLPLNFRKDELKGIYKDRMKIGASLADVDPMQLDSSVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDREFLFSLPDKDARKEILKIHTRDWNPKPLDMFLEELAENSVGYCGADIKSICSEAALCALRRRYPQIYTTSEKLQLDLSSINISAKDFEVAMQKMIPASQRAVTSPGQALSTIVKPLLQSTVHKILEALQRVFPHAETRTNKALDSDISCPLLESDLAYSDDDVPSVYENGLSQKSFNKAKENFNFLHLNRNACYQPMSFRPRMLIVGEPGFGQGSHLAPAVIHALEKFTVYTLDIPVLFGVSATSPEETCAQVIREAKRTAPSIVYVPHIHLWWEIVGPTLKATFTTLLQNIPSFAPVLLLATSDKPHSTLPEEVQELFIHDYGEIFNVQLPSKEERTQFFEDLILKQAAKPPISKKKAVLQALEVLPVAPPPEPRPLTAEELKRLEEQEEDTFRELRIFLRNVTHRLAIDKRFRIFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLSDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESRKKRGCSSSKYAPSYYHVMPKQNSTPAGDKKSDPEQSEKPNRPSTPMACSTPAQLKRKVRKKSKWYLGTITKRRKISQAKDDSQNVTGDKIESDTEENQDTSVDHNETGNTGESSMEENASESKIELENNNSSPCIENEPEESGKTTACTELRKDKIACNGDASSSRIIDIFDENETKEMCVLRMTRARRSQVEQQQLISVEKALAILSQPTPSLVVDHERLKNLLKIVVKKSREYNIFQLENLYAVISQCIYQHRRDYDKTALIQKMEQEVENFSCSRS", "length": 1373, "header": "tr|E1BC78-1|E1BC78_BOVIN Isoform 1 of ATPase family AAA domain-containing protein 2 OS=Bos taurus OX=9913 GN=ATAD2 PE=3 SV=4 CANONICAL=E1BC78-1" }, "isoforms": [ { "isoform_ac": "E1BC78-1", "url": "https://www.uniprot.org/uniprotkb/E1BC78/entry#E1BC78-1", "sequence": { "sequence": 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"length": 1373, "header": "tr|E1BC78-1|E1BC78_BOVIN Isoform 1 of ATPase family AAA domain-containing protein 2 OS=Bos taurus OX=9913 GN=ATAD2 PE=3 SV=4 CANONICAL=E1BC78-1" }, "locus": { "chromosome": "14", "start_pos": 16516409, "end_pos": 16454701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061524.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061524.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053735.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053735.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 129, "start_aa": "Thr", "end_pos": 129, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr129", "evidence": [ { "id": "", 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"3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A4FUD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A4FUD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD9" } ] } ] }, { "uniprot_ac": "A4K436", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A4K436", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4K436" } ] } ] }, { "uniprot_ac": "A5D7C1", "gene_name": "DDX52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] } ] }, { "uniprot_ac": "A5PJA1", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] } ] }, { "uniprot_ac": "A5PJI5", "gene_name": "GET3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A5PJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJI5" } ] } ] }, { "uniprot_ac": "A6QLE5", "gene_name": "NLRP3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A6QLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLE5" } ] } ] }, { "uniprot_ac": "A6QLJ0", "gene_name": "ERCC2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] } ] }, { "uniprot_ac": "A6QQR4", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] } ] }, { "uniprot_ac": "A7YSY2", "gene_name": "AFG2B", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] } ] }, { "uniprot_ac": "A7Z019", "gene_name": "SMARCA4", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-BTA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-BTA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-BTA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "M0RE23-1", "protein_name": "Large ribosomal subunit protein uL24", "gene_name": "Rpl26-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIQKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIEKMQE", "length": 145 }, "evidence": [ { "id": "E1BCF5", "url": "https://omabrowser.org/oma/group/E1BCF5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9FJX2-1", "protein_name": "Large ribosomal subunit protein uL24y", "gene_name": "RPL26B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKFNPRVSSSRRKNRKAHFTAPSSVRRVLMSSPLSKDLRNKHNVRSMPIRKDDEVQVVRGTFKGREGKVMQVYRRKWVIHIERITREKVNGSTVNVGVNASNVMITKLRLDKDRKSLLERKANGRAAADKEKGTKFSAEDVMENVD", "length": 146 }, "evidence": [ { "id": "E1BCF5", "url": "https://omabrowser.org/oma/group/E1BCF5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BCF5", "url": "https://www.uniprot.org/uniprotkb/E1BCF5" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "E1BCF5", "url": "https://www.uniprot.org/uniprotkb/E1BCF5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "E1BCF5", "url": "https://www.uniprot.org/uniprotkb/E1BCF5" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", 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"E1BCF8-1", "uniprot_ac": "E1BCF8", "uniprot_id": "E1BCF8_BOVIN", "mass": { "chemical_mass": 100755.0, "monoisotopic_mass": 100755.0 }, "refseq": { "ac": "XP_003586054", "name": "zinc finger CCCH-type antiviral protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586054" }, "gene_names": [ { "name": "ZC3HAV1", "type": "recommended", "evidence": [ { "id": "E1BCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" } ] }, { "name": "ZC3HAV1", "type": "synonym", "evidence": [ { "id": "XP_003586054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586054" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH-type containing, antiviral 1", "type": "synonym", "evidence": [ { "id": "E1BCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCF8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCCH-type antiviral protein 1", "type": "synonym", "evidence": [ { "id": "XP_003586054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586054" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCF8", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZC3HAV1", "url": "https://www.uniprot.org/uniprotkb/E1BCF8", "locus": { "chromosome": "4", "start_pos": 102659900, "end_pos": 102709121, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021617", "url": "https://www.ensembl.org/id/ENSBTAG00000021617" } ] } } ], "crossref": [ { "id": "E1BCF8", "url": "https://alphafold.ebi.ac.uk/entry/E1BCF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021617", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021617", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01439", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01439", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614589", "url": "https://www.ncbi.nlm.nih.gov/gene/614589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051712", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051712", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614589", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614589", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KWKSPTS", "url": "https://omabrowser.org/oma/group/KWKSPTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCF8", "url": "https://www.orthodb.org/?gene=E1BCF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45740:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45740:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18606", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18606", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18633", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18633", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23466", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23466", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003586054", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586054", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCF8", "url": "https://www.uniprot.org/uniprotkb/E1BCF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCF8-1", "url": "https://www.uniprot.org/uniprotkb/E1BCF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADPGVCCFITKILCAHGGRMALEELLHEMQLSEEQLCEVLKEAGPDRFVVLEMGGKEGVTRSVVATTRARVCRRKYCNKPCGNLHLCKLNLLGRCHYSQSERNLCKYSHEVLSEDNFRVLTNHGLSGLNQEELAVLLLQSDPFFMPEICKNYKGEGGRQICNQQPPCERLHICEHFTRGNCGYANCFRSHNLMDRRVLAVMREHGLSSSVVQNIQDICNSRHRQKKPSAWKAPPPHRRDLAFRGRSKSRDRGSEEFLPAASASAQRSCSPSPEPPGHRGSVASDGPVEDLARQFSHLGSQECPPPASNPSAAVVLGGTPQGGGNQRLAENGSAKDLFYGNHSHAPLTFDLKPAFNWKGPASWQNDQDTGKKSWLPSSPVFSSSPGSPQTPETRKTTAVLSSDHVNAERRSGNQDGQHFPLFADKADGMAVDTTSTRRANYQTPSSRQREKSLPRNPDTGTPRSHLPTAGQMTGDGAAAFVNDSVPNVASTISSTMNEHSSNEICLDHLYKSCQLKSCNKVHFHLPYRWQMLLANSWVDLPFMEDIEKAFCDPKNCSVSVRTYNINFQKMICDFNPVRRISTPSSVTQPPSSLLTTKWIWYWRNGTKWVPYGEKKDNEQISSIDSSYLESLFLSCPRGIVPFQAGSRNYELSFQGMIQTNIASKTQKDVIRRPTFVSYWDVEQVKRRQDPQQGQTSSEPFINIYLPQPDTSVPGSNGFELLEIPSNTPEYAKVSDHFKASMRNFKIEKIKKVQNAQLLEAFKSKKNEMKREEQILFCATERSNVASICKNNFDWLLHGSHDTKYGKGNYFTKDAFSSHKNCPFDSRNIVMFVARVLVGNFIEGHTSYRSPPLQYDSCVDTRLNPSVFVIFQKDQIYPEYVIEYTEPERSEKPCLIS", "length": 896, "header": "tr|E1BCF8-1|E1BCF8_BOVIN Isoform 1 of Zinc finger CCCH-type containing, antiviral 1 OS=Bos taurus OX=9913 GN=ZC3HAV1 PE=3 SV=2 CANONICAL=E1BCF8-1" }, "isoforms": [ { "isoform_ac": "E1BCF8-1", "url": "https://www.uniprot.org/uniprotkb/E1BCF8/entry#E1BCF8-1", "sequence": { "sequence": "MADPGVCCFITKILCAHGGRMALEELLHEMQLSEEQLCEVLKEAGPDRFVVLEMGGKEGVTRSVVATTRARVCRRKYCNKPCGNLHLCKLNLLGRCHYSQSERNLCKYSHEVLSEDNFRVLTNHGLSGLNQEELAVLLLQSDPFFMPEICKNYKGEGGRQICNQQPPCERLHICEHFTRGNCGYANCFRSHNLMDRRVLAVMREHGLSSSVVQNIQDICNSRHRQKKPSAWKAPPPHRRDLAFRGRSKSRDRGSEEFLPAASASAQRSCSPSPEPPGHRGSVASDGPVEDLARQFSHLGSQECPPPASNPSAAVVLGGTPQGGGNQRLAENGSAKDLFYGNHSHAPLTFDLKPAFNWKGPASWQNDQDTGKKSWLPSSPVFSSSPGSPQTPETRKTTAVLSSDHVNAERRSGNQDGQHFPLFADKADGMAVDTTSTRRANYQTPSSRQREKSLPRNPDTGTPRSHLPTAGQMTGDGAAAFVNDSVPNVASTISSTMNEHSSNEICLDHLYKSCQLKSCNKVHFHLPYRWQMLLANSWVDLPFMEDIEKAFCDPKNCSVSVRTYNINFQKMICDFNPVRRISTPSSVTQPPSSLLTTKWIWYWRNGTKWVPYGEKKDNEQISSIDSSYLESLFLSCPRGIVPFQAGSRNYELSFQGMIQTNIASKTQKDVIRRPTFVSYWDVEQVKRRQDPQQGQTSSEPFINIYLPQPDTSVPGSNGFELLEIPSNTPEYAKVSDHFKASMRNFKIEKIKKVQNAQLLEAFKSKKNEMKREEQILFCATERSNVASICKNNFDWLLHGSHDTKYGKGNYFTKDAFSSHKNCPFDSRNIVMFVARVLVGNFIEGHTSYRSPPLQYDSCVDTRLNPSVFVIFQKDQIYPEYVIEYTEPERSEKPCLIS", "length": 896, "header": "tr|E1BCF8-1|E1BCF8_BOVIN Isoform 1 of Zinc finger CCCH-type containing, antiviral 1 OS=Bos taurus OX=9913 GN=ZC3HAV1 PE=3 SV=2 CANONICAL=E1BCF8-1" }, "locus": { "chromosome": "4", "start_pos": 102708922, "end_pos": 102660904, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028806.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028806.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028806.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028806.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614589", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614589", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZZJ3-1", "protein_name": "Zinc finger CCCH-type containing, antiviral 1", "gene_name": "ZC3HAV1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADPGVCCFITKILCTHGGRMALEELLQKVKLSEAQLCEVLTTAGPDRFVLLETGGKAGVTRSVVATTRVRVCRRKYCNRQCGNLHLCKLNLLGRCHYSQSERNLCKYSHEVLSDENFRVLNSHELSGLNKEELAVLLVQSDPFFMPEICKNYKGEGGRQICNQQPPCERLHVCEHFTRGNCSYSNCFRSHNLMDRKVLAVMREHGLSSSVVQNIQDICNSRHRRNKPSGARAPSSHRRDRGRSKSRERLCQDSVEFLPSASAAARVSRTPSPDSAGRHSSPDDGLVEHLATKFKGLGSHDCPQLSSVSSAATSQGGTGPRGGSQSFLENGSPESLLLVNCGGSIFSLASPPAPNWKGPTSWQNNKDPSRESSFSPNQAVTFSPLGSPQTPQATSTRKSPTLFSSDFVNLEGRSGNQDGQPFQLFHNNVDAVATDVASRKSLSYKSATSRQREKSLPRSPDAGAAHGLLQPAGKVAEDAAAAAFGNGSAPDARSTASSMMDDHGSNEICLDHLDKGCQLKNCSKVHFHLPYRWQMLSANTWMDLSLMENVEEAFCDPKVSVLSIGNYKLNFQEMTCDYNPIRRLSTPSSVTRPPGTVFTTKWVWYWKSGPNTWVRYGEKKDNQISNIDSAYLESFFLSCPRGIVPFQAGSQNFELSFPGMIQTNVASKVQKDVVRRPTFVSHWDVEQMKRGMGPPQVQPQLEPPAPTFLPQWDTHFSASNGYKLLEIHNYTPEYVEVSGRFKASMKNFKIDKIKKIQNTKLLNAFERKKHEVKVERILFCVKRRADVESICANNFDSDGTHDTKYGKGIYFTKDAISSHKDCPYDSKNVAMFVVRVLVGNFVEGHPYFTSPPLGFNSCVDTRLNPSVFVIFEKDQIYPEYLIEYTETDKPCVIS", "length": 894 }, "evidence": [ { "id": "E1BCF8", "url": "https://omabrowser.org/oma/group/E1BCF8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZRG1-1", "protein_name": "Zinc finger CCCH-type containing, antiviral 1", "gene_name": "ZC3HAV1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGDPVVCSFLTKTLCAEGGRLGLAELQQHVGLSAQQLQETLQAAGPERFLLLTGAGGAPEVLALTAVRICMRKQCEGCERLHLCKLHLMGRCSLRHRVCKYSHDITSAENKKVLKTHELSGLSENELRILLLQNDPFLLPDACQFYNNRVNTCSQRDDCNKLHICRYFLHGGCKFFPCKKSHNFLDSCALRLLKNGGIDEKMASNIQKVYDHKHVELHKREKPNGPSYKPRQTSEEDRTNKSSKEQKPSFETPEVSTVHAPPSEAVLFSQPSHADRSSNKTHQSEREFLTGTRSKVEGKKDDSSVNSSKDNKDKSDEICLFNVWKYCKHNEKCTSVHYHLPYRWQVYNGITWNDLSMMEEIEKAYCDPKNSSAADKGINFQTMTLSSSLIRRLSTPSSVVNPTFVLTTKWIWYWKNDHGQWTEYGTQGEQGIVNSPSSDILENLYLADPDTTIQFQAGLYYYQLNFKEMIQINTSSKTKRKVCRRPKFVSYEEVQKIKERGQRDSIPSQACPPHWDQSALPDFGYKEVEISTISSEYQEIKKQFEQTMKSCNIIKILRIQNPSLWKVFQWQKEQMKRQSGGKEVKERLLFHGTMGCLLEDICSHNFDWRVCGSNGNLYGKGSYFASDASYSHGYCQSAGKSTVMFMARVLVGDYAQGKEHYVRPPAKLVGGFQFYDSCVDDVANPSIFVIFEKNQIYPEYLIEYKDVQKKCIVC", "length": 714 }, "evidence": [ { "id": "E1BCF8", "url": "https://omabrowser.org/oma/group/E1BCF8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HH79-1", "protein_name": "Zinc finger CCCH-type antiviral protein 1 isoform X1", "gene_name": "Zc3hav1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADPGVCCFITKILCAHGGRMTLEELLAEIALPEAQLRELLEAAGPDRFVQLEIVGQTGVTRSVVATTRARVCRRKYCERPCDSLHLCKLNLLGRCHYSHSQRNLCKYSHEVLSEQNFQVLKNHELSGLNQEELAVLLVQSDPFFMPEICKSYKGEGRKQICGQPQPCERLHICEHFTRGNCSYLNCLRSHNLMDRKVLAIMKEHGLSSDVVQNIQDICNSKHSRRNPPAMRAPQPHRRGRARGRSKSRDRFFQNSLEFLPTVSPAESGPPSPDATSCKGSLEDVSADVTQKFKYLGTQDCAQLSSVSPKAAGLRGAGLKFSENGDPGGLFSRSCSDSSSNLAASGFHLDVTQTLEAMAKKTDKLSGYHMDVKNRSKAHDKQHVPFFDSCAGGAKMEGTASGILGNRATANGLGEILPSNHRKSAGNLLDLQITSRVADSIADSGQDMAFLGGKYGGNTVWASKSTHSDPNGSSQIMNKTPDVSKSSATGFGVKAAVTGRKEAMSFGGQSLRSQVLAMPEEITAAVPASRLPQTPPPSSSHRVAASEILGKNSTHATVSPVCKPSRRTSDSEYPLFSIASSTSPRMDDHGPKEICQDHLYKGCHQSNCNKSHFHLPYRWQLFIDNSWVDFQDMEDIERAYCDPQTESVMIGEYQINFQKMTCDYFPIRRLSTPSFDAQSVNSVFSTTWLWYWKDEFNKYVQYGDENKSHLSSNISSSYLESFFQSCPRGVLPFQAGSQNYELSFQGMIQTNIASKTQRRVVRRPVFVAWKDVERRRRGADRQPVMPAVEALTLDSPPLRDTGTFPFPSNRYELVELDSQDVEYATISELFKASMKYFKIVSIKRIWNQDLWETFERKKLMMKNDNEMLLFHATCRVHVDYICRNNFDWIINDSRETKYGKGNYFAKEAMYSHKNCSYEAKNIVMLVARVLAGNSIEGNMRYSSAPALYDSCVDSRLNPSVFVIFQKEQIYPAYVIEYTELEKEKACIIS", "length": 989 }, "evidence": [ { "id": "E1BCF8", "url": "https://omabrowser.org/oma/group/E1BCF8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q7Z2W4-1", "protein_name": "Zinc finger CCCH-type antiviral protein 1", "gene_name": "ZC3HAV1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGITRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKVLKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRGNCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQMLIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPANSVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYELSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPDHQPAKTSSVSLTATFRPQEDFCFLSSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQMKEEGKLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNCPYDAKNVVMFVAQVLVGKFTEGNITYTSPPPQFDSCVDTRSNPSVFVIFQKDQVYPQYVIEYTEDKACVIS", "length": 902 }, "evidence": [ { "id": "E1BCF8", "url": "https://omabrowser.org/oma/group/E1BCF8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K3Y6-1", "protein_name": "Zinc finger CCCH-type antiviral protein 1", "gene_name": "Zc3hav1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADPGVCCFITKILCAHGGRMTLEELLGEIRLPEAQLYELLETAGPDRFVLLETGGQAGITRSVVATTRARVCRRKYCQRPCDSLHLCKLNLLGRCHYAQSQRNLCKYSHDVLSEQNFQILKNHELSGLNQEELACLLVQSDPFFLPEICKSYKGEGRKQTCGQPQPCERLHICEHFTRGNCSYLNCLRSHNLMDRKVLTIMREHGLSPDVVQNIQDICNNKHARRNPPGTRAAHPHRRGGAHRDRSKSRDRFLHNSLEFLSPVVSPLGSGPPSPDVTSCKDSLEDVSVDVTQKFKYLGTHDRAQLSPVSSKAAGVQGPSQMRASQEFSEDGNLDDIFSRNRSDSSSSRASAAKVAQRNEAVAMKMGMEVKGKKEAPDIDRVPFLNSYIDGVTMEKASVSGIPGKKFTANDLENLLLLNDTWKNVAKPQDLQTTGRITDSGQDKAFLQNKYGGNPVWASASTHNAPNGSSQIMDETPNVSKSSTSGFAIKPAIAGGKEAVYSGVQSPRSQVLAVPGEATTPVQSNRLPQSPLSSSSHRAAASGSPGKNSTHTSVSPAIESSRMTSDPDEYLLRYILNPLFRMDNHGPKEICQDHLYKGCQQSHCDRSHFHLPYRWQMFVYTTWRDFQDMESIEQAYCDPHVELILIENHQINFQKMTCDSYPIRRLSTPSYEEKPLSAVFATKWIWYWKNEFNEYIQYGNESPGHTSSDINSAYLESFFQSCPRGVLPFQAGSQKYELSFQGMIQTNIASKTQRHVVRRPVFVSSNDVEQKRRGPE", "length": 776 }, "evidence": [ { "id": "E1BCF8", "url": "https://omabrowser.org/oma/group/E1BCF8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BCF8", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BCF8", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BCF8", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "E1BCF8", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of viral genome replication", "id": "GO:0045071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045071", "evidence": [ { "database": "UniProtKB", "id": "E1BCF8", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "E1BCF8", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" } ], "pmid": "" }, { "name": "positive regulation of RIG-I signaling pathway", "id": "GO:1900246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900246", "evidence": [ { "database": "UniProtKB", "id": "E1BCF8", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" } ], "pmid": "" }, { "name": "positive regulation of mRNA catabolic process", "id": "GO:0061014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061014", "evidence": [ { "database": "UniProtKB", "id": "E1BCF8", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCF8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 896, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BCF8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BCF8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 173, "end_pos": 194, "start_aa": "Ile", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" }, { "id": "PS51059", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PARP catalytic", "eco_id": "ECO_0000259", "start_pos": 705, "end_pos": 896, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCF8" }, { "id": "PS50918", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50918" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WWE", "eco_id": "ECO_0000259", "start_pos": 586, "end_pos": 671, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 331, "end_pos": 333 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 604, "end_pos": 606 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BCH0-1", "uniprot_ac": "E1BCH0", "uniprot_id": "E1BCH0_BOVIN", "mass": { "chemical_mass": 49449.0, "monoisotopic_mass": 49449.0 }, "refseq": {}, "gene_names": [ { "name": "SYT15B", "type": "recommended", "evidence": [ { "id": "E1BCH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH0" } ] } ], "protein_names": [ { "name": "Synaptotagmin 15B", "type": "synonym", "evidence": [ { "id": "E1BCH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCH0", "url": "https://www.uniprot.org/uniprotkb/E1BCH0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SYT15B", "url": "https://www.uniprot.org/uniprotkb/E1BCH0", "locus": {} } ], "crossref": [ { "id": "E1BCH0", "url": "https://alphafold.ebi.ac.uk/entry/E1BCH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018356", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018356", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08390", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08390", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08409", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08409", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BCH0", "url": "https://www.orthodb.org/?gene=E1BCH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024:SF234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024:SF234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BCH0", "url": "https://www.uniprot.org/uniprotkb/E1BCH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCH0-1", "url": "https://www.uniprot.org/uniprotkb/E1BCH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RHRHRRDQAPGPRPRRPARAAPWKVALVVGGILGGLLLLLLLTGVSYYLWKRLCATFTYEELSETTAASSTQGDALCPLDARTQASRPPGVPFVVPPSLQSQDWVPRSSREWAQVPQDPYPAPELLPHTTGSNLGDACVAGTINPELYKIPEDQSEADFPEGCLGRLWFSVEYQQEAERLLVGLIKAQRLHAPSENCSPLVKLHLLPDERRFLQSKTKCRTTSPQFNEHFVFQVSSKSVNQRVLRFSVYHVDRQRKHQLLGQVLFPLKKETLVGNCRRVLWRDLEAESLEAPSEFGDLQFCLSYNDRLNRLTVVVLRAKGLRLRENTSFVSVFVKVSLMNHNKFVKCKKTSAVLGSTNPVYSETFSFKAVPAELDTASLSLTVLQSAEGDRSHELGRVVVGPYMYTRGRELEHWNEMLSKPKELVKRWHALCRTTEP", "length": 437, "header": "tr|E1BCH0-1|E1BCH0_BOVIN Isoform 1 of Synaptotagmin 15B OS=Bos taurus OX=9913 GN=SYT15B PE=3 SV=4 CANONICAL=E1BCH0-1" }, "isoforms": [ { "isoform_ac": "E1BCH0-1", "url": "https://www.uniprot.org/uniprotkb/E1BCH0/entry#E1BCH0-1", "sequence": { "sequence": "RHRHRRDQAPGPRPRRPARAAPWKVALVVGGILGGLLLLLLLTGVSYYLWKRLCATFTYEELSETTAASSTQGDALCPLDARTQASRPPGVPFVVPPSLQSQDWVPRSSREWAQVPQDPYPAPELLPHTTGSNLGDACVAGTINPELYKIPEDQSEADFPEGCLGRLWFSVEYQQEAERLLVGLIKAQRLHAPSENCSPLVKLHLLPDERRFLQSKTKCRTTSPQFNEHFVFQVSSKSVNQRVLRFSVYHVDRQRKHQLLGQVLFPLKKETLVGNCRRVLWRDLEAESLEAPSEFGDLQFCLSYNDRLNRLTVVVLRAKGLRLRENTSFVSVFVKVSLMNHNKFVKCKKTSAVLGSTNPVYSETFSFKAVPAELDTASLSLTVLQSAEGDRSHELGRVVVGPYMYTRGRELEHWNEMLSKPKELVKRWHALCRTTEP", "length": 437, "header": "tr|E1BCH0-1|E1BCH0_BOVIN Isoform 1 of Synaptotagmin 15B OS=Bos taurus OX=9913 GN=SYT15B PE=3 SV=4 CANONICAL=E1BCH0-1" }, "locus": { "chromosome": "28", "start_pos": 41786711, "end_pos": 41778835, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024426.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024426.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024426.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024426.6" } ] } } ], "glycosylation": [], "phosphorylation": [], 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exocytosis", "id": "GO:0017158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017158", "evidence": [ { "database": "UniProtKB", "id": "E1BCH0", "url": "https://www.uniprot.org/uniprotkb/E1BCH0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "E1BCH0", "url": "https://www.uniprot.org/uniprotkb/E1BCH0" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "E1BCH0", "url": "https://www.uniprot.org/uniprotkb/E1BCH0" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "E1BCH0", "url": "https://www.uniprot.org/uniprotkb/E1BCH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCH0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 437, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BCH0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BCH0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BCH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH0" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 163, "end_pos": 282, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 326, "end_pos": 328 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BCH2-1", "uniprot_ac": "E1BCH2", "uniprot_id": "E1BCH2_BOVIN", "mass": { "chemical_mass": 41513.0, "monoisotopic_mass": 41513.0 }, "refseq": { "ac": "NP_001179413", "name": "SH3 and cysteine-rich domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179413" }, "gene_names": [ { "name": "STAC3", "type": "recommended", "evidence": [ { "id": "E1BCH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ] }, { "name": "STAC3", "type": "synonym", "evidence": [ { "id": "NP_001179413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179413" } ] } ], "protein_names": [ { "name": "SH3 and cysteine-rich domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "E1BCH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH2/entry#names_and_taxonomy" } ] }, { "name": "SH3 and cysteine-rich domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "NP_001179413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179413" } ] } ], "function": [ { "annotation": "Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane. Slows down the inactivation rate of the calcium channel CACNA1C.", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2#function" }, { "database": "UniProtKB", "id": "ARBA00057005", "url": "https://www.uniprot.org/uniprotkb/ARBA00057005#function" }, { "database": "UniProtKB", "id": "A0ABI0NQ84", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ84#function" } ] }, { "annotation": "STAC3 expression was increased during the differentiation of bovine satellite cells into myotubes.", "evidence": [ { "database": "RefSeq", "id": "NP_001179413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179413" }, { "database": "PubMed", "id": "24948655", "url": "https://glygen.org/publication/PubMed/24948655" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "STAC3", "url": "https://www.uniprot.org/uniprotkb/E1BCH2", "locus": { "chromosome": "5", "start_pos": 56199668, "end_pos": 56193530, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018358", "url": "https://www.ensembl.org/id/ENSBTAG00000018358" } ] } } ], "crossref": [ { "id": "E1BCH2", "url": "https://alphafold.ebi.ac.uk/entry/E1BCH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018358", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018358", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11834", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11834", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11986", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11986", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20882", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20882", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "518234", "url": "https://www.ncbi.nlm.nih.gov/gene/518234", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:518234", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518234", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NEEWWRI", "url": "https://omabrowser.org/oma/group/NEEWWRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCH2", "url": "https://www.orthodb.org/?gene=E1BCH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15135", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15135", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15135:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15135:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179413", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ84", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ84-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCH2-1", "url": "https://www.uniprot.org/uniprotkb/E1BCH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEKEVLESSSFPSETRKGRLQRLKQLFRKESTGTKEMELPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSSANRNDPVFETLRTGVIMANKERKKGQADKKNSLAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDETGGYVKVYTGRKVGLFPTDFLEEI", "length": 362, "header": "tr|E1BCH2-1|E1BCH2_BOVIN Isoform 1 of SH3 and cysteine-rich domain-containing protein 3 OS=Bos taurus OX=9913 GN=STAC3 PE=4 SV=1 CANONICAL=E1BCH2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQ84-1", "url": "https://www.uniprot.org/uniprotkb/E1BCH2/entry#A0ABI0NQ84-1", "sequence": { "sequence": "MTEKEVLESSSFPSETRKGRLQRLKQLFRKESTGTKEMELPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSSANRNDPVFETLRTGVIMANKERKKGQADKKNSLAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQVALVPQLKARPRGSSSNYTPFRS", "length": 353, "header": "tr|A0ABI0NQ84-1|A0ABI0NQ84_BOVIN Computationally mapped isoform of SH3 and cysteine-rich domain-containing protein 3 OS=Bos taurus OX=9913 GN=STAC3 PE=4 SV=1 CANONICAL=E1BCH2-1" }, "locus": { "chromosome": "5", "start_pos": 56199108, "end_pos": 56194434, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149177.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149177.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104304.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104304.1" } ] } }, { "isoform_ac": "E1BCH2-1", "url": "https://www.uniprot.org/uniprotkb/E1BCH2/entry#E1BCH2-1", "sequence": { "sequence": "MTEKEVLESSSFPSETRKGRLQRLKQLFRKESTGTKEMELPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSSANRNDPVFETLRTGVIMANKERKKGQADKKNSLAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDETGGYVKVYTGRKVGLFPTDFLEEI", "length": 362, "header": "tr|E1BCH2-1|E1BCH2_BOVIN Isoform 1 of SH3 and cysteine-rich domain-containing protein 3 OS=Bos taurus OX=9913 GN=STAC3 PE=4 SV=1 CANONICAL=E1BCH2-1" }, "locus": { "chromosome": "5", "start_pos": 56199297, "end_pos": 56194434, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024422.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024422.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024422.5", "url": "https://www.ensembl.org/id/ENSBTAP00000024422.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification of the STAC3 gene as a skeletal muscle-specifically expressed gene and a novel regulator of satellite cell differentiation in cattle.", "journal": "Journal of animal science", "date": "2014-08", "authors": "Zhang Y, Cong X, Wang A, Jiang H", "evidence": [ { "database": "RefSeq", "id": "NP_001179413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179413" } ], "reference": [ { "type": "PubMed", "id": "24948655", "url": "https://glygen.org/publication/PubMed/24948655" } ] } ], "pathway": [ { "id": "bta:518234", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518234", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQN6-1", "protein_name": "SH3 and cysteine-rich domain-containing protein 3", "gene_name": "Stac3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEKEVVESPQPPFPGETPQSGLQRLKQLFKKGSPETTEMEPPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQKCFGKIPPGFHRAYSSPLYSNQQYACVSAANRNDPVFETLRVGVIMANKERKKGQADKKNPLAAMMEEEPESARPEEGKSQDGNDAEKDKKAEKKTPDDKNKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI", "length": 361 }, "evidence": [ { "id": "E1BCH2", "url": "https://omabrowser.org/oma/group/E1BCH2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BZ71-1", "protein_name": "SH3 and cysteine-rich domain-containing protein 3", "gene_name": "Stac3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEKEVVESPQPPFPGETPQSGLQRLKQLFKKGSPETAEMEPPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFRRAYSSPLYSDQQYAVSAANRNDPVFETLRVGVIMANKERKKGQADKKNPLAAMMEEEPESARPEEGKSQDGNNAEKDKKAEKKTPDDKNKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI", "length": 360 }, "evidence": [ { "id": "E1BCH2", "url": "https://omabrowser.org/oma/group/E1BCH2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96MF2-1", "protein_name": "SH3 and cysteine-rich domain-containing protein 3", "gene_name": "STAC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI", "length": 364 }, "evidence": [ { "id": "E1BCH2", "url": "https://omabrowser.org/oma/group/E1BCH2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" }, { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" }, { "name": "T-tubule", "id": "GO:0030315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030315", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" }, { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BCH2", "url": "https://www.uniprot.org/uniprotkb/E1BCH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], 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"sequence": "MKAPCVSLCLLGAGLFLCSVHARGLRRCLISMNLHRVEESFRGIKTAIQAKDTFQNVTILSPSETLHGIKPLDVCCVTKNLLAFYVDRVFKDHQELNPQIMRKISSLANSFLYMQKTLQQCQNLCHCRQEATNATRIIHDNYDQLEVRSAAVKSLGELDVFLAWIDKHHRGTSAASR", "length": 177, "header": "tr|E1BCI0-1|E1BCI0_BOVIN Isoform 1 of Interleukin family protein OS=Bos taurus OX=9913 GN=IL19 PE=3 SV=2 CANONICAL=E1BCI0-1" }, "locus": { "chromosome": "16", "start_pos": 4633188, "end_pos": 4627787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008801.5", "url": "https://www.ensembl.org/id/ENSBTAT00000008801.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008801.4", "url": "https://www.ensembl.org/id/ENSBTAP00000008801.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:527634", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527634", "resource": "KEGG Pathway" }, { "id": "R-BTA-5684996", "name": "", "url": 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scrofa", "sequence": { "sequence": "MKARCVSLCLLGTMLFLCSAHARGLRRCLISIDMHRIEESFRGIKKAIQAKDTMQNVTILSPSESLHSIKPLDACCMTKNLLAFYVDRVFKDHQELDPQLLRKISSIANSFLYMQKTLQQCHEQRLCHCRQEATNATRIIHDNYDQLEVRSAAIKSLGELDIFLAWIDKNHQGTSDASGQGT", "length": 182 }, "evidence": [ { "id": "E1BCI0", "url": "https://omabrowser.org/oma/group/E1BCI0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GZS9-1", "protein_name": "Interleukin family protein", "gene_name": "Il19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKAQNISHWLLGMALVLCSVHTHSLRRCLISVDRSLIEKSFPEIKRALQTNDTFPNVTILSTLENLKSIQPVDVCCVTSRLLTFYRDRVFKDHQETSPEVMRQISSIANSFLYMQKTLEQCQVHNQCHCSQEATNATRTIHDNYDQLEASSAALKSLGELDIFLAWIDENHQETSTA", "length": 177 }, "evidence": [ { "id": "E1BCI0", "url": "https://omabrowser.org/oma/group/E1BCI0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8CJ70-1", "protein_name": 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"type": "recommended", "evidence": [ { "id": "E1BCI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCI4" } ] }, { "name": "KCNJ14", "type": "synonym", "evidence": [ { "id": "NP_001192950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192950" } ] } ], "protein_names": [ { "name": "ATP-sensitive inward rectifier potassium channel 14", "type": "recommended", "evidence": [ { "id": "E1BCI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCI4/entry#names_and_taxonomy" } ] }, { "name": "ATP-sensitive inward rectifier potassium channel 14", "type": "synonym", "evidence": [ { "id": "NP_001192950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192950" } ] }, { "name": "Inward rectifier K(+) channel Kir2.4", "type": "synonym", "evidence": [ { "id": "E1BCI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCI4/entry#names_and_taxonomy" } ] }, { "name": "Potassium channel, 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Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.", "evidence": [ { "database": "UniProtKB", "id": "E1BCI4", "url": "https://www.uniprot.org/uniprotkb/E1BCI4#function" }, { "database": "UniProtKB", "id": "ARBA00054205", "url": "https://www.uniprot.org/uniprotkb/ARBA00054205#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCI4", "url": "https://www.uniprot.org/uniprotkb/E1BCI4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KCNJ14", "url": "https://www.uniprot.org/uniprotkb/E1BCI4", "locus": { "chromosome": "18", "start_pos": 55140481, "end_pos": 55136649, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000082", "url": "https://www.ensembl.org/id/ENSBTAG00000000082" } ] } } ], "crossref": [ { "id": "E1BCI4", "url": "https://alphafold.ebi.ac.uk/entry/E1BCI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000082", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000082", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540740", "url": "https://www.ncbi.nlm.nih.gov/gene/540740", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540740", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540740", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHNGWAP", "url": "https://omabrowser.org/oma/group/CHNGWAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCI4", "url": "https://www.orthodb.org/?gene=E1BCI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01007", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01007", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17655", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17655", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1296053", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296053", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192950", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192950", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BCI4", "url": "https://www.uniprot.org/uniprotkb/E1BCI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCI4-1", "url": "https://www.uniprot.org/uniprotkb/E1BCI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLARALRRLSGALESGDDRAGDEEEAGPGLCHNGWAPAQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDLTAPPPPAPCFSQVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDRRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAERASQSPKSGFPSCLAAFCYENELALSCCQEEDEEEEATEGDAAEAEDKAASPQVLTPTLALTLPP", "length": 434, "header": "tr|E1BCI4-1|E1BCI4_BOVIN Isoform 1 of ATP-sensitive inward rectifier potassium channel 14 OS=Bos taurus OX=9913 GN=KCNJ14 PE=3 SV=1 CANONICAL=E1BCI4-1" }, "isoforms": [ { "isoform_ac": "E1BCI4-1", "url": "https://www.uniprot.org/uniprotkb/E1BCI4/entry#E1BCI4-1", "sequence": { "sequence": 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"phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540740", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540740", "resource": "KEGG Pathway" }, { "id": "R-BTA-1296053", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296053", "resource": "Reactome", "description": "Classical Kir channels" }, { "id": "R-BTA-5576886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576886", "resource": "Reactome", "description": "Phase 4 - resting membrane potential" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RL84-1", "protein_name": "ATP-sensitive inward rectifier potassium channel 14", "gene_name": "KCNJ14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"MGLARALRRLSGALEPGNSRAGDEEEAGAGLCRNGWAPGPVAGNRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLTFWLIASLHGDLAAPPPPAPCFSQVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDRRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSPKSSFPGSLAAFCYENELALSCCQEEDEEEDTKEGTSAETPDRAASPQALTPTLALTLPP", "length": 434 }, "evidence": [ { "id": "E1BCI4", "url": "https://omabrowser.org/oma/group/E1BCI4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8JZN3-1", "protein_name": "ATP-sensitive inward rectifier potassium channel 14", "gene_name": "Kcnj14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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{ "chromosome": "13", "start_pos": 48228283, "end_pos": 48213050, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000073.6", "url": "https://www.ensembl.org/id/ENSBTAT00000000073.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000073.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000073.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 437, "start_aa": "Thr", "end_pos": 437, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr437", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], 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"id": "E1BCK3-1", "url": "https://www.uniprot.org/uniprotkb/E1BCK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNHNFKYPASCCHPQERIPVHFCIFLKMSHSKFIPTVSIQSPVHHTNLKVQSTEPSFKKEDLHLISKDSLESDSESPTQKIKSQSDLEDQIQDNDMEPDSLEEENLSETEEEASRKAAQRAKKENLHTQDAAAINSRQPTEDKYSHLRYDPNWKSKKEEGKLLPVEALPESVDSSTENLTLNPLYPSKEPSMDLSAGKGEQKSPRSTASLLGSEFVSPNYELSTHRTEPFSVLSDSDPEEKSSNLSRYLKSSSSRSEAFLPGSRGPRRRKSKQYFVEKNKLTLGLPTPRMDSYLQLHNKKRGEGHLEQISYPVRVTDKTSIQNARETGNVAIDPEDKWHQRAQQLKDYQEHWSQYEHEKSSSGPRGQSSETTNGQQPSRKPAKHKIRKQRRHRHGPKSLVTEELVVSQGNQNNTPRHQQNPNKPIDTEVTQETVVIMNATNDDLQYSSVLRSQDPTVTSNQYAPLHQISDKVLYKNPARYYPVTNANRERGHNDQEEKRFSYQQLHIDTLSDMHLNYLHELNKKHPSGSQKGSQSVSNINRQASTEKKKQPKLAYTETKYKNLEILWKFHSSSEEQPAKASPDSRLSQIMEQHQQALLQLTEVQPHEGASPGLTLPPILPRVESESQLSSERSQRNQVKISRSNSESYLFQLEKGKKHRKRSSIKSSKLKGYQNRDVKLGGLGPDLESIRDKMQKLIQQKEYAKQVKEYNMKALSIPSKPQTAITENKSAVPRQKALEYAKTIPKPKPSNLSDQASKEKKTPTHAGKEDTLPEISLLEVLQNRHEREKQAVAAFKVLHIV", "length": 800, "header": "tr|E1BCK3-1|E1BCK3_BOVIN Isoform 1 of Junctional cadherin complex regulator OS=Bos taurus OX=9913 GN=JHY PE=4 SV=4 CANONICAL=E1BCK3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQ80-1", "url": "https://www.uniprot.org/uniprotkb/E1BCK3/entry#A0ABI0NQ80-1", "sequence": { "sequence": 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"MNHNFKYPASCCHPQERIPVHFCIFLKMSHSKFIPTVSIQSPVHHTNLKVQSTEPSFKKEDLHLISKDSLESDSESPTQKIKSQSDLEDQIQDNDMEPDSLEEENLSETEEEASRKAAQRAKKENLHTQDAAAINSRQPTEDKYSHLRYDPNWKSKKEEGKLLPVEALPESVDSSTENLTLNPLYPSKEPSMDLSAGKGEQKSPRSTASLLGSEFVSPNYELSTHRTEPFSVLSDSDPEEKSSNLSRYLKSSSSRSEAFLPGSRGPRRRKSKQYFVEKNKLTLGLPTPRMDSYLQLHNKKRGEGHLEQISYPVRVTDKTSIQNARETGNVAIDPEDKWHQRAQQLKDYQEHWSQYEHEKSSSGPRGQSSETTNGQQPSRKPAKHKIRKQRRHRHGPKSLVTEELVVSQGNQNNTPRHQQNPNKPIDTEVTQETVVIMNATNDDLQYSSVLRSQDPTVTSNQYAPLHQISDKVLYKNPARYYPVTNANRERGHNDQEEKRFSYQQLHIDTLSDMHLNYLHELNKKHPSGSQKGSQSVSNINRQASTEKKKQPKLAYTETKYKNLEILWKFHSSSEEQPAKASPDSRLSQIMEQHQQALLQLTEVQPHEGASPGLTLPPILPRVESESQLSSERSQRNQVKISRSNSESYLFQLEKGKKHRKRSSIKSSKLKGYQNRDVKLGGLGPDLESIRDKMQKLIQQKEYAKQVKEYNMKALSIPSKPQTAITENKSAVPRQKALEYAKTIPKPKPSNLSDQASKEKKTPTHAGKEDTLPEISLLEVLQNRHEREKQAVAAFKVLHIV", "length": 800, "header": "tr|E1BCK3-1|E1BCK3_BOVIN Isoform 1 of Junctional cadherin complex regulator OS=Bos taurus OX=9913 GN=JHY PE=4 SV=4 CANONICAL=E1BCK3-1" }, "locus": { "chromosome": "15", "start_pos": 33584395, "end_pos": 33505355, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054834.4", "url": "https://www.ensembl.org/id/ENSBTAT00000054834.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047568.4", "url": "https://www.ensembl.org/id/ENSBTAP00000047568.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "E1BCK3", "url": "https://www.uniprot.org/uniprotkb/E1BCK3" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "E1BCK3", "url": "https://www.uniprot.org/uniprotkb/E1BCK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" }, { "start_pos": 750, "end_pos": 752, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCK3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 800, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BCK9-1", "uniprot_ac": "E1BCK9", "uniprot_id": "E1BCK9_BOVIN", "mass": { "chemical_mass": 147421.0, "monoisotopic_mass": 147421.0 }, "refseq": { "ac": "XP_024855404", "name": "snRNA-activating protein complex subunit 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855404" }, "gene_names": [ { "name": "SNAPC4", "type": "recommended", "evidence": [ { "id": "E1BCK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCK9" } ] }, { "name": "SNAPC4", "type": "synonym", "evidence": [ { "id": "XP_024855404", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855404" } ] } ], "protein_names": [ { "name": "snRNA-activating protein complex subunit 4", "type": "recommended", "evidence": [ { "id": "E1BCK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCK9/entry#names_and_taxonomy" } ] }, { "name": "snRNA-activating protein complex 190 kDa subunit", "type": "synonym", "evidence": [ { "id": "E1BCK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCK9/entry#names_and_taxonomy" } ] }, { "name": "snRNA-activating protein complex subunit 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024855404", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855404" } ] } ], "function": [ { "annotation": "Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.", "evidence": [ { "database": "UniProtKB", "id": "E1BCK9", "url": "https://www.uniprot.org/uniprotkb/E1BCK9#function" }, { "database": "UniProtKB", "id": "ARBA00025193", "url": "https://www.uniprot.org/uniprotkb/ARBA00025193#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCK9", "url": "https://www.uniprot.org/uniprotkb/E1BCK9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SNAPC4", "url": "https://www.uniprot.org/uniprotkb/E1BCK9", "locus": { "chromosome": "11", "start_pos": 103833612, "end_pos": 103855064, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000054", "url": "https://www.ensembl.org/id/ENSBTAG00000000054" } ] } } ], "crossref": [ { "id": "ENSBTAG00000000054", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000054", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512086", "url": "https://www.ncbi.nlm.nih.gov/gene/512086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512086", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAFHQTK", "url": "https://omabrowser.org/oma/group/MAFHQTK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCK9", "url": "https://www.orthodb.org/?gene=E1BCK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46621", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46621", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46621:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46621:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-76071", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76071", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024855404", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855404", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCK9", "url": "https://www.uniprot.org/uniprotkb/E1BCK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCK9-1", "url": "https://www.uniprot.org/uniprotkb/E1BCK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVDAERERISREIQQLERILDPCCSSVSMDVSESSLNSDSDADLLPDEDLDSDAAGPLLSEEERWGEASNDEDDPKEKALPEDPETCLQLNMVYQEVVREKLAEVSLLLAQNREQQEEVMGDLVGVKGPKVKDDRNPPPNLYLGHFMKPYFRDRVTGVGPPANEDTREKAAQGIKAFTELLVTKWKTWEKVLLRKSVVSDRLQRLLQPKLLKLEYLQQKQSRATSELEKQILEKQAREAEKEVQDINQLPEEALLGDRLDSHDWDKISNVNFEGGRSTEEIRKFWQNHEHPSINKQEWSEQEVAQLKAVAAKHGHLDWQSIAEELGTHRSAFQCLQRYQQHNPALKRREWTEEEDRMLTRLVQAMRVGSHIPYRRIVYYMEGRDSMQLIYRWTKSLDPSLRKGLWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNSKEVKKLIELIEKYGVGHWAKIASELPHRSGSQCLSKWKIMVRQRQRARRRARWSPSSGSSSNSSWEDSEPEEAPKDVPEEAPAGGPEPPPAQYAVPDMDLWVPARQSTEELRGAVAGGCPRPPEGPDTAQATAPAPTGQLASRSRSADPRTVGCLCPATAHRWSSKGLLGKERLRQPHPPGSAPGLSPGGGSRDEARPRVQPQWARTAQRRQGHALQRRLLEHKLLTAVSPWVGEVDLLCARPRPAMRPRRADGIRRQLQGAHLASTPVFALLIQLFQIDVTGCMEVVRERKAWPPALLQAGAGDPLPLQEPSSAHSAPGCLTQSVPAQGAAKQSTCPEGGRGPQACCTASMPRAAAPAPCRPRPKPKTVSELLREKRLREARARRAAQGPAVLSARVLVSTPMVLQPLAPPGASVSRVVLSGPGGPPVTSSSVSGSWAPVKNERAPTLHAFALSPATSRAPGQVPASCPLSALGQSQAPATSRKQGLPEAPPLLPAAPSPVQLPVQPLSLTPALGMPAAASTPLPVTWVLTAQGLLPVPLQAMVSLPPPTGAPDPTQLSVILPPSPTETRASRGPRLPEQSRPGPPAASTDLEPEPPCRTEPLSKSPTEVAEACGLAELTSHEEEALVSGETSAPRTPSQDTPLAHHPATGPPSSSPQPLHGAPGAASGPREPQPLDLEEPQPLDLEEPLLPWLGLENGPLDLSLLSQESEVATQEWLRGQQGVPVPALGSQLAYQPPTLCSLRALSGLLLRKKDLEHGAAVLAPGGPAGALQASLGRVRERLHDSPAYLLLRARFLAAFTLPALLATLSPRGVPTTLSASTGPDPETDSDDFDPEEPELTDSDGQPGDPAQGAPDPSQGSAPSCPDSPDNLDVLQTRRSRHVRKRRRLQ", "length": 1351, "header": "tr|E1BCK9-1|E1BCK9_BOVIN Isoform 1 of snRNA-activating protein complex subunit 4 OS=Bos taurus OX=9913 GN=SNAPC4 PE=4 SV=3 CANONICAL=E1BCK9-1" }, "isoforms": [ { "isoform_ac": "E1BCK9-1", "url": "https://www.uniprot.org/uniprotkb/E1BCK9/entry#E1BCK9-1", "sequence": { "sequence": "MDVDAERERISREIQQLERILDPCCSSVSMDVSESSLNSDSDADLLPDEDLDSDAAGPLLSEEERWGEASNDEDDPKEKALPEDPETCLQLNMVYQEVVREKLAEVSLLLAQNREQQEEVMGDLVGVKGPKVKDDRNPPPNLYLGHFMKPYFRDRVTGVGPPANEDTREKAAQGIKAFTELLVTKWKTWEKVLLRKSVVSDRLQRLLQPKLLKLEYLQQKQSRATSELEKQILEKQAREAEKEVQDINQLPEEALLGDRLDSHDWDKISNVNFEGGRSTEEIRKFWQNHEHPSINKQEWSEQEVAQLKAVAAKHGHLDWQSIAEELGTHRSAFQCLQRYQQHNPALKRREWTEEEDRMLTRLVQAMRVGSHIPYRRIVYYMEGRDSMQLIYRWTKSLDPSLRKGLWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNSKEVKKLIELIEKYGVGHWAKIASELPHRSGSQCLSKWKIMVRQRQRARRRARWSPSSGSSSNSSWEDSEPEEAPKDVPEEAPAGGPEPPPAQYAVPDMDLWVPARQSTEELRGAVAGGCPRPPEGPDTAQATAPAPTGQLASRSRSADPRTVGCLCPATAHRWSSKGLLGKERLRQPHPPGSAPGLSPGGGSRDEARPRVQPQWARTAQRRQGHALQRRLLEHKLLTAVSPWVGEVDLLCARPRPAMRPRRADGIRRQLQGAHLASTPVFALLIQLFQIDVTGCMEVVRERKAWPPALLQAGAGDPLPLQEPSSAHSAPGCLTQSVPAQGAAKQSTCPEGGRGPQACCTASMPRAAAPAPCRPRPKPKTVSELLREKRLREARARRAAQGPAVLSARVLVSTPMVLQPLAPPGASVSRVVLSGPGGPPVTSSSVSGSWAPVKNERAPTLHAFALSPATSRAPGQVPASCPLSALGQSQAPATSRKQGLPEAPPLLPAAPSPVQLPVQPLSLTPALGMPAAASTPLPVTWVLTAQGLLPVPLQAMVSLPPPTGAPDPTQLSVILPPSPTETRASRGPRLPEQSRPGPPAASTDLEPEPPCRTEPLSKSPTEVAEACGLAELTSHEEEALVSGETSAPRTPSQDTPLAHHPATGPPSSSPQPLHGAPGAASGPREPQPLDLEEPQPLDLEEPLLPWLGLENGPLDLSLLSQESEVATQEWLRGQQGVPVPALGSQLAYQPPTLCSLRALSGLLLRKKDLEHGAAVLAPGGPAGALQASLGRVRERLHDSPAYLLLRARFLAAFTLPALLATLSPRGVPTTLSASTGPDPETDSDDFDPEEPELTDSDGQPGDPAQGAPDPSQGSAPSCPDSPDNLDVLQTRRSRHVRKRRRLQ", "length": 1351, "header": "tr|E1BCK9-1|E1BCK9_BOVIN Isoform 1 of snRNA-activating protein complex subunit 4 OS=Bos taurus OX=9913 GN=SNAPC4 PE=4 SV=3 CANONICAL=E1BCK9-1" }, "locus": { "chromosome": "11", "start_pos": 103853971, "end_pos": 103833622, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000060.6", "url": "https://www.ensembl.org/id/ENSBTAT00000000060.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000060.5", "url": "https://www.ensembl.org/id/ENSBTAP00000000060.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1028, "start_aa": "Thr", "end_pos": 1028, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1028", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:512086", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512086", "resource": "KEGG Pathway" }, { "id": "R-BTA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" }, { "id": "R-BTA-76071", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76071", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 3 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1ACK4-1", "protein_name": "snRNA-activating protein complex subunit 4", "gene_name": "SNAPC4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRRDGPAGANLNAEREKIRREIEELERSLQLDVTSVDVAVSDSSLSSDDAEGDSSDAHAEMEVEREEDSSDDDLESSLLEDPETCLQMNYVYQEVIQEKIEEVELLIAQNKEQQKEILCELDGRKTTRTGDGRNLPSNIFLGHFMKPYFKDKTTGIGPPSNEDAKEKAAQGIKSFEQLLSTKWKSKEKVLLQKSVVSDRLQRLLQPKLLKLSYSNQKLENVKTEMEKQILEKQIKEVEREIEAINQLPESDLLGGRFDEHDWEKIANVHFDGRRSSEELKKFWQNWEHPNINKNEWTEEETERLKDIAAKRGYLDWQTVAQELGTNRTAFQCLQKYQAYNKDLKRKEWTRDEDKMLLELVQEMRVGSHIPYKKIAYYMEGRDSAQLIYRWTKSVDPSLKKGPWTPEEDAMLLAAVEKYGERDWYKIRAEVPGRSDAQCSDRYLKALHRDVKKGKWSLKEEEQLIDLVQKHGLGHWSKIASELPHRTRSQCLSKWKIMIGSKKRSRSAKRQHAEESSSCSESSSEDVELDLSDTSEEEKMNKEECTFPSIDLWIPTQTDVLESCQGRHQASSPFSFGSANARTSSSKIPNARREGGEEGANAKATELSTILRGMARPHSTDITVKNPKEEINKASRCGKQVLRVTLEDVRRVLRENTCFQRKRQSKLIMSSAATLTKTSGVGASAAEKHRGLWSTMGKSRRQERARWRKMNLDRKLLMAVTPWVGDVLLPCTLRAGKMAFDQTKAYSIQQKLKSVSLSSTPLFTLFIQLFRIDTNGCMKIIRERRADAARPQQASQNLESSSGNASQPPSNTQRALPALPSPPAPLAQAHRQKPKTVSELLREKRQMEKQLKEKAMQTKVFVAPQMMLSGPLIIQHPPQQMIPSAQVGSKPGAGGSTDSQVQCVSASPSAFTSVAGSASTPVVLESHSPSVPKVGELPGSSQETKVQSNKELNEQGPQNTPERGLFPSLNPAAAGKAPDRGGCNAQVLAGTSAPVVFQNQAFVPRRVTVVPFGIDSGNSKLSLPAPITYELTHSGPVNLLPALLAPQPGSHLTPDSMLPLTWVVTQQALLSSAVQAVVGVPQGLQAIVRSQSQASVTSSGSVSGLGAPPVSSGVNMPHPSHAETKTNPQLAAGSPAGKTAGVSHSASVFPVSSADPVCSVSGVSSATSAHSDSSSKTVDSSAAHNALPGGAPTLHAQLLPQMQLPASTEGSDSRCVTDVVSLGEKQDSSTTNGSSSNSDVLHKGDELQPRASIPHNSVAGNSEGSADQGLKYRPIASKPPPEQTESAPPQPTTSSAEKTLLDYSLISLEDDELVKEWLSGKQGVQVPPLQTRLPYFPPFLCNLKTLSKLLLQKAALEKQAARFLSPDGSQTEGEVDLNAITKLVHEKLGDDPAFLLLKARFLAAFTLPAVLATLPPPKVATTLSASKREYGESDEEEWQSEEEASEDESCGDELDAPSDETGGDEPGDRDADFPSKGMETEDSAAQSIVGTCTDGTASVPQIRRSVRIRKRFTKRRRV", "length": 1518 }, "evidence": [ { "id": "E1BCK9", "url": "https://omabrowser.org/oma/group/E1BCK9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1LYZ6-1", "protein_name": "snRNA-activating protein complex subunit 4", "gene_name": "Snapc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDIDAEREKVTQEIQELERILYPGSSSVHFEVSESSLSSDSEADPLPDEDLETAGAPVLEEERSSEGSNDDEDPKDKALPEDPETCLQLNMVYQEVIREKLAEVSQLLAQNQEQQEEILFDLAGTKCPKVKDAKSLPSYMYIGHFLKPYFKDKVTGVGPPANEETREKAAQGIKAFEQLLVTKWKHWEKDLLRKSVVSDRLQRLLQPKLLKLEYLQEKQSRVSSELEKQALEKQIKEAEKEIQDINQLPEEALLGNRLDSHDWEKISNVNFEGARSAEEIRKFWQSSEHPSINKKEWSTEEVERLKTIAASHGHLEWHLVAEELGTSRSAFQCLQKFQQYNKALKRKEWTEEEDHMLTQLVQEMRVGNHIPYRRIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWAPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKKGRWDAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKILARKKQHLQKRRGQRSRHSSQWSSCSSSSSSSSSSSGSEDYGGGSSSSSNSSEDSEVELEEPLQNSRALAPQQYSVPDIDLWVPTRLIDSRSQREETGCYPVHPAVSCRTQNHHKEGSTVVSAPERNQMQECCETHSTVPRGVQSLHSSDTHGASVKEPACKSHTLVKERRRQPPLPNSRSGSDPGNSMAGPHLRRLWHGTFQNKQRRKRQALHRRLLKHRLLLAVIPWVGDINLACTQAVQRPAAVQTQADSIRMQLECARLASTPVFTLFIQLLQIDTAGCMEVVQERKTQPPALLQPGTRNTQPHLLQASSNAKNNTGCLLPGMLDEQTAKRTSQKGRPRLGSCKAEATPFQVPVAAPRGLRPKPKTVSELLREKRLRESHAKKATQALTALSSQLLVSSPVLLQPPLLPAARGSPVVGPAASSVELSVPVAPVMVSSSPSGSWQVGGISATDKQPPNLQTIPLNPSHKGTQIAAPAAFRSLALASGHVSTGCPLNTLGQTSTTSQKQSLPKVLPILPAAPSLTQLSVQPLSLPPVLNPPASGQPPATKSSLPVSWVLTTQKLLSVQVPAVVGLPQPVTTPETIGLQAKQLPSPSKTPAFLGQPPASTDTEPKGPQGQQTPPTPGPEKKALDLSLLSQESEAAILTWLTGSQGACVPPLGSRMSYHPPSLCSLRALSSLLLHKKDLEQKASSLVAGQAAGAQPEPKAGALQASLELVQRQFQNNPAYLLLKTRFLAIFSLPAFLATLPPNSVPTTLSPAMAVGSESDSEDFGDLEPRDGATQLDCMACRVRANLMAPDPVVSHLPSWERRAPSPSAVSAPSHLDASDDLDDLDVLRTRHARHSRK", "length": 1345 }, "evidence": [ { "id": "E1BCK9", "url": "https://omabrowser.org/oma/group/E1BCK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5SXM2-1", "protein_name": "snRNA-activating protein complex subunit 4", "gene_name": "SNAPC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVDAEREKITQEIKELERILDPGSSGSHVEISESSLESDSEADSLPSEDLDPADPPISEEERWGEASNDEDDPKDKTLPEDPETCLQLNMVYQEVIQEKLAEANLLLAQNREQQEELMRDLAGSKGTKVKDGKSLPPSTYMGHFMKPYFKDKVTGVGPPANEDTREKAAQGIKAFEELLVTKWKNWEKALLRKSVVSDRLQRLLQPKLLKLEYLHQKQSKVSSELERQALEKQGREAEKEIQDINQLPEEALLGNRLDSHDWEKISNINFEGSRSAEEIRKFWQNSEHPSINKQEWSREEEERLQAIAAAHGHLEWQKIAEELGTSRSAFQCLQKFQQHNKALKRKEWTEEEDRMLTQLVQEMRVGSHIPYRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGVGHWAKIASELPHRSGSQCLSKWKIMMGKKQGLRRRRRRARHSVRWSSTSSSGSSSGSSGGSSSSSSSSSEEDEPEQAQAGEGDRALLSPQYMVPDMDLWVPARQSTSQPWRGGAGAWLGGPAASLSPPKGSSASQGGSKEASTTAAAPGEETSPVQVPARAHGPVPRSAQASHSADTRPAGAEKQALEGGRRLLTVPVETVLRVLRANTAARSCTQKEQLRQPPLPTSSPGVSSGDSVARSHVQWLRHRATQSGQRRWRHALHRRLLNRRLLLAVTPWVGDVVVPCTQASQRPAVVQTQADGLREQLQQARLASTPVFTLFTQLFHIDTAGCLEVVRERKALPPRLPQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRLPAFGGVIPATEPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPLPQPGPEKGALDLGLLSQEGEAATQQWLGGQRGVRVPLLGSRLPYQPPALCSLRALSGLLLHKKALEHKATSLVVGGEAERPAGALQASLGLVRGQLQDNPAYLLLRARFLAAFTLPALLATLAPQGVRTTLSVPSRVGSESEDEDLLSELELADRDGQPGCTTATCPIQGAPDSGKCSASSCLDTSNDPDDLDVLRTRHARHTRKRRRLV", "length": 1469 }, "evidence": [ { "id": "E1BCK9", "url": "https://omabrowser.org/oma/group/E1BCK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BP86-1", "protein_name": "snRNA-activating protein complex subunit 4", "gene_name": "Snapc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDIDAEREKITQEIQELERILYPGSTSVHFEVSESSLSSDSEADSLPDEDLETAGAPILEEEGSSESSNDEEDPKDKALPEDPETCLQLNMVYQEVIREKLAEVSQLLAQNQEQQEEILFDLSGTKCPKVKDGRSLPSYMYIGHFLKPYFKDKVTGVGPPANEETREKATQGIKAFEQLLVTKWKHWEKALLRKSVVSDRLQRLLQPKLLKLEYLHEKQSRVSSELERQALEKQIKEAEKEIQDINQLPEEALLGNRLDSHDWEKISNINFEGARSAEEIRKFWQSSEHPSISKQEWSTEEVERLKAIAATHGHLEWHLVAEELGTSRSAFQCLQKFQQYNKTLKRKEWTEEEDHMLTQLVQEMRVGNHIPYRKIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWAPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKKGRWNAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKILARKKQHLQRKRGQRPRHSSQWSSSGSSSSSSEDYGSSSGSDGSSGSENSDVELEASLEKSRALTPQQYRVPDIDLWVPTRLITSQSQREGTGCYPQHPAVSCCTQDASQNHHKEGSTTVSAAEKNQLQVPYETHSTVPRGDRFLHFSDTHSASLKDPACKSHTLMKERPKQPLLPSSRSGSDPGNNTAGPHLRQLWHGTYQNKQRRKRQALHRRLLKHRLLLAVIPWVGDINLACTQAPRRPATVQTKADSIRMQLECARLASTPVFTLLIQLLQIDTAGCMEVVRERKSQPPALLQPGTRNTQPHLLQASSNAKNNTGCLPSMTGEQTAKRASHKGRPRLGSCRTEATPFQVPVAAPRGLRPKPKTVSELLREKRLRESHAKKATQALGLNSQLLVSSPVILQPPLLPVPHGSPVVGPATSSVELSVPVAPVMVSSSPSGSWPVGGISATDKQPPNLQTISLNPPHKGTQVAAPAAFRSLALAPGQVPTGGHLSTLGQTSTTSQKQSLPKVLPILRAAPSLTQLSVQPPVSGQPLATKSSLPVNWVLTTQKLLSVQVPAVVGLPQSVMTPETIGLQAKQLPSPAKTPAFLEQPPASTDTEPKGPQGQEIPPTPGPEKAALDLSLLSQESEAAIVTWLKGCQGAFVPPLGSRMPYHPPSLCSLRALSSLLLQKQDLEQKASSLAASQAAGAQPDPKAGALQASLELVQRQFRDNPAYLLLKTRFLAIFSLPAFLATLPPNSIPTTLSPDVAVVSESDSEDLGDLELKDRARQLDCMACRVQASPAAPDPVQSHLVSPGQRAPSPGEVSAPSPLDASDGLDDLNVLRTRRARHSRR", "length": 1333 }, "evidence": [ { "id": "E1BCK9", "url": "https://omabrowser.org/oma/group/E1BCK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "snRNA-activating protein complex", "id": "GO:0019185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019185", "evidence": [ { "database": "UniProtKB", "id": "E1BCK9", "url": "https://www.uniprot.org/uniprotkb/E1BCK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "snRNA transcription by RNA polymerase II", "id": "GO:0042795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042795", "evidence": [ { "database": "UniProtKB", "id": "E1BCK9", "url": "https://www.uniprot.org/uniprotkb/E1BCK9" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase III", "id": "GO:0042796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042796", "evidence": [ { "database": "UniProtKB", "id": "E1BCK9", "url": "https://www.uniprot.org/uniprotkb/E1BCK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "E1BCK9", "url": "https://www.uniprot.org/uniprotkb/E1BCK9" } ], "pmid": "" }, { "name": "RNA polymerase III type 3 promoter sequence-specific DNA binding", "id": "GO:0001006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001006", "evidence": [ { "database": "UniProtKB", "id": "E1BCK9", "url": "https://www.uniprot.org/uniprotkb/E1BCK9" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "E1BCK9", "url": "https://www.uniprot.org/uniprotkb/E1BCK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BCK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCK9" }, { "id": "PS51294", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51294" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH myb-type", "eco_id": "ECO_0000259", "start_pos": 291, "end_pos": 347, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BCK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCK9" }, { "id": "PS50090", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50090" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb-like", "eco_id": "ECO_0000259", "start_pos": 291, "end_pos": 343, "start_aa": "His", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BCK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCK9" }, { "id": "PS51293", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51293" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SANT", "eco_id": "ECO_0000259", "start_pos": 406, "end_pos": 447, "start_aa": "Trp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1028 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 522, "end_pos": 524 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BCL1-1", "uniprot_ac": "E1BCL1", "uniprot_id": "E1BCL1_BOVIN", "mass": { "chemical_mass": 52033.0, "monoisotopic_mass": 52033.0 }, "refseq": { "ac": "NP_001137580", "name": "homeobox protein PKNOX2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137580" }, "gene_names": [ { "name": "PKNOX2", "type": "recommended", "evidence": [ { "id": "E1BCL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ] }, { "name": "PKNOX2", "type": "synonym", "evidence": [ { "id": "NP_001137580", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137580" } ] } ], "protein_names": [ { "name": "PBX/knotted 1 homeobox 2", "type": "synonym", "evidence": [ { "id": "E1BCL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCL1/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein PKNOX2", "type": "synonym", "evidence": [ { "id": "NP_001137580", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137580" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PKNOX2", "url": "https://www.uniprot.org/uniprotkb/E1BCL1", "locus": { "chromosome": "29", "start_pos": 28893936, "end_pos": 28766169, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000052", "url": "https://www.ensembl.org/id/ENSBTAG00000000052" } ] } } ], "crossref": [ { "id": "E1BCL1", "url": "https://alphafold.ebi.ac.uk/entry/E1BCL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000052", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000052", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "617454", "url": "https://www.ncbi.nlm.nih.gov/gene/617454", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617454", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617454", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WERFINA", "url": "https://omabrowser.org/oma/group/WERFINA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCL1", "url": "https://www.orthodb.org/?gene=E1BCL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11850", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11850", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001137580", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137580", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMQHASPAPALTMMATQNVPPPAYQDSPQMTATAQAPSKAQAVHISTPSAAASTPVPTAPIDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDNATMAMQQAMMAAHDDSLDGTEEEEEDEMEEEEEEELEEEADELQTTNVSDLGLEHSDSLE", "length": 472, "header": "tr|E1BCL1-1|E1BCL1_BOVIN Isoform 1 of PBX/knotted 1 homeobox 2 OS=Bos taurus OX=9913 GN=PKNOX2 PE=3 SV=1 CANONICAL=E1BCL1-1" }, "isoforms": [ { "isoform_ac": "E1BCL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1/entry#E1BCL1-1", "sequence": { "sequence": "MMQHASPAPALTMMATQNVPPPAYQDSPQMTATAQAPSKAQAVHISTPSAAASTPVPTAPIDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDNATMAMQQAMMAAHDDSLDGTEEEEEDEMEEEEEEELEEEADELQTTNVSDLGLEHSDSLE", "length": 472, "header": "tr|E1BCL1-1|E1BCL1_BOVIN Isoform 1 of PBX/knotted 1 homeobox 2 OS=Bos taurus OX=9913 GN=PKNOX2 PE=3 SV=1 CANONICAL=E1BCL1-1" }, "locus": { "chromosome": "29", "start_pos": 28892932, "end_pos": 28809868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000057.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000057.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000057.4", "url": "https://www.ensembl.org/id/ENSBTAP00000000057.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617454", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617454", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYQ2-1", "protein_name": "PBX/knotted 1 homeobox 2", "gene_name": "Pknox2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMQHASPAPALTMMATQNVPPPPYQDSPQMTATAQPPSKAQAVHIAAPSATASTPVPSAPIDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGTPGTNPDGSINLDNLQSLSSDNATMAMQQAMMAAHDDSLDGTEEEDEDDMEEEEEEEEELEEEEADELQTTNVSDLGLEHSDSLE", "length": 475 }, "evidence": [ { "id": "E1BCL1", "url": "https://omabrowser.org/oma/group/E1BCL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2LN05-1", "protein_name": "Homeobox protein PKNOX2 isoform X1", "gene_name": "Pknox2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMQHASPAPALTMMATQNVPPPPYQDSPQMTATTQAPAKAQAVHISAPSATASTPVPSAPIDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGALYQPVTMVTSQGQVVTQAIPQGAIQIQSTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGTPGTNPDGSINLDNLQSLSSDNATMAMQQAMMAAHDDSLDGTEEEDEDDMEEEEEEEEELEEEADELQTTNVSDLGLEHSDSLE", "length": 474 }, "evidence": [ { "id": "E1BCL1", "url": "https://omabrowser.org/oma/group/E1BCL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BG99-1", "protein_name": "Homeobox protein PKNOX2", "gene_name": "Pknox2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMQHASPAPALTMMATQNVPPPPYQDSPQMTATAQPPSKAQAVHISAPSATASTPVPSAPIDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGTPGTNPDGSINLDNLQSLSSDNATMAMQQAMMAAHDDSLDGTEEEDEDDMEEEEEEEEELEEEADELQTTNVSDLGLEHSDSLE", "length": 474 }, "evidence": [ { "id": "E1BCL1", "url": "https://omabrowser.org/oma/group/E1BCL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96KN3-1", "protein_name": "Homeobox protein PKNOX2", "gene_name": "PKNOX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQHASPAPALTMMATQNVPPPPYQDSPQMTATAQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDSATMAMQQAMMAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDELQTTNVSDLGLEHSDSLE", "length": 472 }, "evidence": [ { "id": "E1BCL1", "url": "https://omabrowser.org/oma/group/E1BCL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ], "pmid": "" }, { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BCL1", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCL1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 472, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BCL1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BCL1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BCL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCL1" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 286, "end_pos": 349, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 329, "end_pos": 331 }, { "start_pos": 412, "end_pos": 414 }, { "start_pos": 459, "end_pos": 461 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"chromosome": "13", "start_pos": 78918165, "end_pos": 78927531, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003398", "url": "https://www.ensembl.org/id/ENSBTAG00000003398" } ] } } ], "crossref": [ { "id": "E1BCM0", "url": "https://alphafold.ebi.ac.uk/entry/E1BCM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003398", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003398", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539813", "url": "https://www.ncbi.nlm.nih.gov/gene/539813", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539813", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539813", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAFRNIL", "url": "https://omabrowser.org/oma/group/CAFRNIL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCM0", "url": "https://www.orthodb.org/?gene=E1BCM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF88", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF88", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192648", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192648", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCM0", "url": "https://www.uniprot.org/uniprotkb/E1BCM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCM0-1", "url": "https://www.uniprot.org/uniprotkb/E1BCM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLLPGDNSDYDYSALSCTSDASFHPAFFPQSQSLKGVFYRRAQRLRPQDEPRQGGQPEDRRRQIIINVGGIKYSLPWTTLEEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIQEFAETVEREDEEDALDSEDPDSEGPAEEEGRLGRCMRRLRDMVERPHSGLPGKVFAFLSVLFVTVTAVNLSISTLPSLREEEEQGRCSQMCRNIFIVESVCVGWFSLEFLLRLIQAPNKFVFLRSPLTLIDMVAILPYYVTLLVDGASAGRRKPGTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMAESPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFRRTQFLIKTKSQLSSMSHDSDILFGSASSDTRDNN", "length": 514, "header": "tr|E1BCM0-1|E1BCM0_BOVIN Isoform 1 of Potassium voltage-gated channel modifier subfamily G member 1 OS=Bos taurus OX=9913 GN=KCNG1 PE=4 SV=1 CANONICAL=E1BCM0-1" }, "isoforms": [ { "isoform_ac": "E1BCM0-1", "url": "https://www.uniprot.org/uniprotkb/E1BCM0/entry#E1BCM0-1", "sequence": { "sequence": "MTLLPGDNSDYDYSALSCTSDASFHPAFFPQSQSLKGVFYRRAQRLRPQDEPRQGGQPEDRRRQIIINVGGIKYSLPWTTLEEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIQEFAETVEREDEEDALDSEDPDSEGPAEEEGRLGRCMRRLRDMVERPHSGLPGKVFAFLSVLFVTVTAVNLSISTLPSLREEEEQGRCSQMCRNIFIVESVCVGWFSLEFLLRLIQAPNKFVFLRSPLTLIDMVAILPYYVTLLVDGASAGRRKPGTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMAESPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFRRTQFLIKTKSQLSSMSHDSDILFGSASSDTRDNN", "length": 514, "header": "tr|E1BCM0-1|E1BCM0_BOVIN Isoform 1 of Potassium voltage-gated channel modifier subfamily G member 1 OS=Bos taurus OX=9913 GN=KCNG1 PE=4 SV=1 CANONICAL=E1BCM0-1" }, "locus": { "chromosome": "13", "start_pos": 78923346, "end_pos": 78918556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004406.3", "url": "https://www.ensembl.org/id/ENSBTAT00000004406.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004406.1", "url": "https://www.ensembl.org/id/ENSBTAP00000004406.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 435, "start_aa": "Thr", "end_pos": 435, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr435", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539813", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539813", "resource": "KEGG Pathway" }, { "id": "R-BTA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HEF9-1", "protein_name": "Potassium voltage-gated channel subfamily G member 1", "gene_name": "Kcng1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTLLPGDNSDYDYSALSCASDTSFHPAFFPQRQAIKGVFYRRAQRLRPQDDLHQGSSLGDRRRQIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILSVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREGEEELLDSEDQDTEGPSASEGRLGRCMRKLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGQCSQMCHNVFIVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDGAASSRRKPSTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVLIRRAQYLIKTKSQLSGMSQDSDILFGSASSDTRDNN", "length": 514 }, "evidence": [ { "id": "E1BCM0", "url": "https://omabrowser.org/oma/group/E1BCM0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A2BDX4-1", "protein_name": "Voltage-gated potassium channel regulatory subunit KCNG1", "gene_name": "Kcng1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLLPGDNSHYDYSALSCASDTSFHPAFFPQRQAIKGVFYRRAQRLRPQDDLHQSCSLGDRRRQIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILSVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMMEREEEEEPLDSEDQESEGPSASEGRLSRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGQCSQMCHNVFIVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDGAASSRRKPSTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVLIRRAQYLIKTKSQLSGMSQDSDILFGSASSDTRDNN", "length": 514 }, "evidence": [ { "id": "E1BCM0", "url": "https://omabrowser.org/oma/group/E1BCM0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5GFZ3-1", "protein_name": "Potassium voltage-gated channel modifier subfamily G member 1", "gene_name": "KCNG1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTLLPGDNSDYDYSALSCASDASFHPAFFPQSQSLKGVFYRRAQRLRPQDEPRQGGQPEDRRRQIIINVGGIKYSLPWTTLEEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREDEDDPLDSEDRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSISTLPSLREEEEQGQCSQMCHNIFVVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERLMFRRTQFLLKTKSPLSSMSHDSDILFGSASSDTRDNN", "length": 514 }, "evidence": [ { "id": "E1BCM0", "url": "https://omabrowser.org/oma/group/E1BCM0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4AD53-1", "protein_name": "Voltage-gated potassium channel regulatory subunit KCNG1", "gene_name": "Kcng1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLLPGDNSDYDYSALSCASDTSFHPAFFPQRQAIKGVFYRRAQRLGPQDDLHQSISLGDRRRQIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILSVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMMEREDEEEALDSEDQESEGPSTSEGRLSRCMRRLRDMVEKPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGQCSQMCHNVFIVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDGAASSRRKPSTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVLIRRAQYLIKTKSQLSGMSQDSDILFGSASSDTRDNN", "length": 514 }, "evidence": [ { "id": "E1BCM0", "url": "https://omabrowser.org/oma/group/E1BCM0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C3M8-1", "protein_name": "Potassium voltage-gated channel modifier subfamily G member 1", "gene_name": "KCNG1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTLLPGENSDYDYSALSCASDASFNHTFFPETETLKGVFYQRAKLIHPEEDLLKGFHPDDRKHHIIINVGGIKYLLPWTTLDEFPLTRLGQLKFCNNFDDILNICDDYDVTCNEFFFDRNPGAFRTILTFLRVGKLRLLREMCALSFQEELLYWGIEEDNLDWCCKRRYLQKMEEFTEINEREDDLIENETTGETVEETKIGLCMKKLQDMVERPQSGLPGKVFACLSVLFVTITAVNLSISTMPDLREEEDKGECSQMCYNIFIVESVCVAWFSLEFLLRFIQAKNKFAFLRRPLTLIDIIAILPYYITLLVDTTSVGYKKPSSGSIYLDKVGLVLRILRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSQEFTSIPACYWWAVITMTTVGYGDMVPRSIPGQVVALSSILSGILLMAFPVTSIFHTFSRSYIELKQEQERIMYRRAQFLLKTKSQISNASQGSDILFPNISTDNRAMNDI", "length": 511 }, "evidence": [ { "id": "E1BCM0", "url": "https://omabrowser.org/oma/group/E1BCM0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9UIX4-1", "protein_name": "Voltage-gated potassium channel regulatory subunit KCNG1", "gene_name": "KCNG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLLPGDNSDYDYSALSCTSDASFHPAFLPQRQAIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFRRAQFLIKTKSQLSVSQDSDILFGSASSDTRDNN", "length": 513 }, "evidence": [ { "id": "E1BCM0", "url": "https://omabrowser.org/oma/group/E1BCM0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BCM0", "url": "https://www.uniprot.org/uniprotkb/E1BCM0" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "E1BCM0", "url": "https://www.uniprot.org/uniprotkb/E1BCM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "E1BCM0", "url": "https://www.uniprot.org/uniprotkb/E1BCM0" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "E1BCM0", "url": "https://www.uniprot.org/uniprotkb/E1BCM0" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "E1BCM0", "url": "https://www.uniprot.org/uniprotkb/E1BCM0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "E1BCM0", "url": "https://www.uniprot.org/uniprotkb/E1BCM0" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "E1BCM0", "url": "https://www.uniprot.org/uniprotkb/E1BCM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCM0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 514, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BCM0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BCM0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BCM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCM0" }, { "id": "SM00225", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 172, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 435 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BCM1-1", "uniprot_ac": "E1BCM1", "uniprot_id": "E1BCM1_BOVIN", "mass": { "chemical_mass": 30330.0, "monoisotopic_mass": 30330.0 }, "refseq": { "ac": "NP_001179266", "name": "SPRY domain-containing SOCS box protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179266" }, "gene_names": [ { "name": "SPSB4", "type": "recommended", "evidence": [ { "id": "E1BCM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCM1" } ] }, { "name": "SPSB4", "type": "synonym", "evidence": [ { "id": "NP_001179266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179266" } ] } ], "protein_names": [ { "name": "SPRY domain-containing SOCS box protein 4", "type": "synonym", "evidence": [ { "id": "NP_001179266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179266" } ] }, { "name": "SplA/ryanodine receptor domain and SOCS box containing 4", "type": "synonym", "evidence": [ { "id": "E1BCM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCM1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCM1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPSB4", "url": "https://www.uniprot.org/uniprotkb/E1BCM1", "locus": { "chromosome": "1", "start_pos": 127831477, "end_pos": 127917561, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009115", "url": "https://www.ensembl.org/id/ENSBTAG00000009115" } ] } } ], "crossref": [ { "id": "E1BCM1", "url": "https://alphafold.ebi.ac.uk/entry/E1BCM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009115", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009115", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03718", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03718", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12906", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12906", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512922", "url": "https://www.ncbi.nlm.nih.gov/gene/512922", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512922", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512922", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRPMAKE", "url": "https://omabrowser.org/oma/group/HRPMAKE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCM1", "url": "https://www.orthodb.org/?gene=E1BCM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12245:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12245:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179266", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179266", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCM1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCM1-1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQKLSGSLKSVEVREPALRPAKRELRGEEPGRPARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQIHWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNRPGVAYPAFLGPEEAFALPDSLLVVLDMDEGTLSFVVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLCRRCIRLALGRQRLQDISSLPLPQSLKNYLQYQ", "length": 273, "header": "tr|E1BCM1-1|E1BCM1_BOVIN Isoform 1 of SplA/ryanodine receptor domain and SOCS box containing 4 OS=Bos taurus OX=9913 GN=SPSB4 PE=3 SV=2 CANONICAL=E1BCM1-1" }, "isoforms": [ { "isoform_ac": "E1BCM1-1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1/entry#E1BCM1-1", "sequence": { "sequence": "MGQKLSGSLKSVEVREPALRPAKRELRGEEPGRPARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQIHWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNRPGVAYPAFLGPEEAFALPDSLLVVLDMDEGTLSFVVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLCRRCIRLALGRQRLQDISSLPLPQSLKNYLQYQ", "length": 273, "header": "tr|E1BCM1-1|E1BCM1_BOVIN Isoform 1 of SplA/ryanodine receptor domain and SOCS box containing 4 OS=Bos taurus OX=9913 GN=SPSB4 PE=3 SV=2 CANONICAL=E1BCM1-1" }, "locus": { "chromosome": "1", "start_pos": 127902068, "end_pos": 127832838, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012013.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012013.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012013.4", "url": "https://www.ensembl.org/id/ENSBTAP00000012013.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512922", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512922", "resource": "KEGG Pathway" }, { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NUQ3-1", "protein_name": "SplA/ryanodine receptor domain and SOCS box containing 4", "gene_name": "SPSB4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGQKISGSIKSVDVREPPFRPVKRELRGPDFCKPARLDMLLDMPPAKLEIQYKHAWNNEDRSLNIFVKEDDKLTFHRHPVAQSTDCIRGKVGYTRGLHVWQIHWPTRQRGTHAVVGVSTAEAPLHSVGYTSLVGSNSESWGWDLGRNKLYHNCKNQPGVTYPVFLEPDESFVLPDSLLVVLDMDEGTLSFMVDGQYLGVAFRGLKGKKLYPIVSAVWGHCEITMRYINGLDPEPLPLMDLCRRSIRFALGRDRLHDIEILPLPLSLKNYLQYQ", "length": 273 }, "evidence": [ { "id": "E1BCM1", "url": "https://omabrowser.org/oma/group/E1BCM1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A1Z6E0-1", "protein_name": "Protein gustavus", "gene_name": "gus", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGQKISGGVKTVSRNDSQSTFKPIIPRELQADFVKPARIDILLDMPPASRDLQLKHSWNSEDRSLNIFVKEDDKLTFHRHPVAQSTDCIRGKVGLTKGLHIWEIYWPTRQRGTHAVVGVCTADAPLHSVGYQSLVGSTEQSWGWDLGRNKLYHDSKNCAGVTYPAILKNDEAFLVPDKFLVALDMDEGTLSFIVDQQYLGIAFRGLRGKKLYPIVSAVWGHCEITMRYIGGLDPEPLPLMDLCRRTIRQKIGRTNLEEHIQQLQLPLSMKTYLLYKNRR", "length": 279 }, "evidence": [ { "id": "E1BCM1", "url": "https://omabrowser.org/oma/group/E1BCM1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "B0S5W3-1", "protein_name": "SPRY domain-containing SOCS box protein 4a", "gene_name": "spsb4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGQKISGSIKSVDVRGEPSFRPLRRELRGPDFFKPARLDLLLDMPPASYEQQLRHAWNSDDRSLNIFIKDDDKLTFHRHPVAQSTDGIRGRVGYTRGLHVWRIHWPARQRGTHAVVGVATGDAPLHSVGYTSLVGSDSESWGWDLGRNKLYHNSKNRPASSAPTYPSFLEPEEAFVLPDTLMVVLDMDEGTLSFMVDGQYLGVAFRGLKGKKLYPIVSAVWGHCEITMRYINGLDPEPLPLMDLCRRAARLALGRERLQEIETLPLPQSLKNYLQYQ", "length": 277 }, "evidence": [ { "id": "E1BCM1", "url": "https://omabrowser.org/oma/group/E1BCM1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B5DF38-1", "protein_name": "SplA/ryanodine receptor domain and SOCS box containing 4", "gene_name": "Spsb4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQKLSGSLKSVEVREPALRPAKRELRGLEPGRPARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQIHWPARQRGTHAVVGVATARAPLHSVGYTALVGSDSESWGWDLGRSRLYHDGKNRPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLCRRSIRSALGRQRLRDIGSLPLPQSLKNYLQYQ", "length": 273 }, "evidence": [ { "id": "E1BCM1", "url": "https://omabrowser.org/oma/group/E1BCM1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R5B6-1", "protein_name": "SPRY domain-containing SOCS box protein 4", "gene_name": "Spsb4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQKLSGSLKSVEVREPALRPAKRELRGLEPGRPARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQIHWPARQRGTHAVVGVATARAPLHSVGYTALVGSDSESWGWDLGRSRLYHDGKNRPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLCRRSIRSALGRQRLRDIGSLPLPQSLKNYLQYQ", "length": 273 }, "evidence": [ { "id": "E1BCM1", "url": "https://omabrowser.org/oma/group/E1BCM1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96A44-1", "protein_name": "SPRY domain-containing SOCS box protein 4", "gene_name": "SPSB4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQKLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ", "length": 273 }, "evidence": [ { "id": "E1BCM1", "url": "https://omabrowser.org/oma/group/E1BCM1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BCM1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "E1BCM1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BCM1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "E1BCM1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BCM1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "E1BCM1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1" } ], "pmid": "" }, { "name": "positive regulation of protein polyubiquitination", "id": "GO:1902916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902916", "evidence": [ { "database": "UniProtKB", "id": "E1BCM1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "E1BCM1", "url": "https://www.uniprot.org/uniprotkb/E1BCM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCM1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 273, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BCM1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BCM1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BCM2-1", "uniprot_ac": "E1BCM2", "uniprot_id": "E1BCM2_BOVIN", "mass": { "chemical_mass": 43071.0, "monoisotopic_mass": 43071.0 }, "refseq": { "ac": "NP_001180079", "name": "translocating chain-associated membrane protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180079" }, "gene_names": [ { "name": "TRAM2", "type": "recommended", "evidence": [ { "id": "E1BCM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCM2" } ] }, { "name": "TRAM2", "type": "synonym", "evidence": [ { "id": "NP_001180079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180079" } ] } ], "protein_names": [ { "name": "Translocating chain-associated membrane protein", "type": "recommended", "evidence": [ { "id": "E1BCM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCM2/entry#names_and_taxonomy" } ] }, { "name": "translocating chain-associated membrane protein 2", "type": "synonym", "evidence": [ { "id": "NP_001180079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180079" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCM2", "url": "https://www.uniprot.org/uniprotkb/E1BCM2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TRAM2", "url": "https://www.uniprot.org/uniprotkb/E1BCM2", "locus": { "chromosome": "23", "start_pos": 24893081, "end_pos": 24962338, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009112", "url": "https://www.ensembl.org/id/ENSBTAG00000009112" } ] } } ], "crossref": [ { "id": "E1BCM2", "url": "https://alphafold.ebi.ac.uk/entry/E1BCM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009112", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009112", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617287", "url": "https://www.ncbi.nlm.nih.gov/gene/617287", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617287", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617287", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LCRLCML", "url": "https://omabrowser.org/oma/group/LCRLCML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCM2", "url": "https://www.orthodb.org/?gene=E1BCM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12371", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12371", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12371:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12371:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180079", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180079", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCM2", "url": "https://www.uniprot.org/uniprotkb/E1BCM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCM2-1", "url": "https://www.uniprot.org/uniprotkb/E1BCM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNVSMPTADGETVQYHYGPKDLVTVLFYIFIAIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHLSSVIWCFYVVVTEGYLTNPRSLWEDYPHVYLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLVLLLLQYSTEFLFHTARLCHFADENNEKLFNAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLLCRLCVLLLVCAAQAWLMWRFIHSQLRHWREYWSEQSAKRRVPAAPRLAARLIKRESGYHENGVVKAENGTSTRTKKLKSP", "length": 370, "header": "tr|E1BCM2-1|E1BCM2_BOVIN Isoform 1 of Translocating chain-associated membrane protein OS=Bos taurus OX=9913 GN=TRAM2 PE=3 SV=2 CANONICAL=E1BCM2-1" }, "isoforms": [ { "isoform_ac": "E1BCM2-1", "url": "https://www.uniprot.org/uniprotkb/E1BCM2/entry#E1BCM2-1", "sequence": { "sequence": "MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNVSMPTADGETVQYHYGPKDLVTVLFYIFIAIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHLSSVIWCFYVVVTEGYLTNPRSLWEDYPHVYLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLVLLLLQYSTEFLFHTARLCHFADENNEKLFNAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLLCRLCVLLLVCAAQAWLMWRFIHSQLRHWREYWSEQSAKRRVPAAPRLAARLIKRESGYHENGVVKAENGTSTRTKKLKSP", "length": 370, "header": "tr|E1BCM2-1|E1BCM2_BOVIN Isoform 1 of Translocating chain-associated membrane protein OS=Bos taurus OX=9913 GN=TRAM2 PE=3 SV=2 CANONICAL=E1BCM2-1" }, "locus": { "chromosome": "23", "start_pos": 24957939, "end_pos": 24893265, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012010.7", "url": "https://www.ensembl.org/id/ENSBTAT00000012010.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012010.5", "url": "https://www.ensembl.org/id/ENSBTAP00000012010.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617287", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617287", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QI79-1", "protein_name": "Translocating chain-associated membrane protein", "gene_name": "Tram2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPTADSETVHYHYGPKDLVTILFYVFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHLSSVVWCLYVVVTEGYLTNLRSLWEDYPHVYLSFQVKFFYLCQLAYWLHSLPELYFQKVRKEEIPRQLQYICLYLLHIAGAYLLNLSRLGLILLLLQYSTEFLFHMARLFYFADENNERLFNAWAAAFGVTRLFILTLAVLAIGFGLARVENQVFDPEKGNFNTLPCRLGMLLLVCVAQAWLMWRFIHSQLRHWREYWKEQSAKRRVPAAPRLPARPIKREPGYHENGVVKAENGTSPRTKKLKSP", "length": 370 }, "evidence": [ { "id": "E1BCM2", "url": "https://omabrowser.org/oma/group/E1BCM2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LU55-1", "protein_name": "Translocation associated membrane protein 2", "gene_name": "Tram2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFRRRTKSYPLFSQEFVIHNHADIVFFLVLCVLIGLMFEVTAKIAFLCILPQYNVSVPTADSETVNYHYGPKDLATILFYILITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHLSSVAWCLYVVATEGYLSNPRSLWEDYPHVYLSLGSALPLHLSKSPGAVPGHTKNSLISSFQVKFFYLGQLAYWLHALPELYFQKVRKEEIPRQLQYICLYLLHIAGAYLLNLSRLGLILLLLQYSTEALFHMARLFYFADENNERLFNAWAAVFGVTRLFIFTLAVLTIGFGLARVENQVFDPEKGNFNTLPCRLGMLLLVCVAQAWLMWRFIHSQLRHWREYWKEQSAKRRVSAVPRLPARLLKREPGFHENGVVKTENGTSSRTKKLKSP", "length": 397 }, "evidence": [ { "id": "E1BCM2", "url": "https://omabrowser.org/oma/group/E1BCM2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P28496-1", "protein_name": "Ceramide synthase LAC1", "gene_name": "LAC1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTIKPSPSNNNLKVRSRPRRKSSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAIRLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVLQLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDSGLAFFSFAIFVVAWIYLRHYINLKILWSVLTQFRTEGNYVLNFATQQYKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRGILKDDRSDSESDEESDESSTTPTDSTPTKKDI", "length": 418 }, "evidence": [ { "id": "E1BCM2", "url": "https://omabrowser.org/oma/group/E1BCM2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q15035-1", "protein_name": "Translocating chain-associated membrane protein 2", "gene_name": "TRAM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPTADSETVHYHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHWREYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP", "length": 370 }, "evidence": [ { "id": "E1BCM2", "url": "https://omabrowser.org/oma/group/E1BCM2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q924Z5-1", "protein_name": "Translocating chain-associated membrane protein 2", "gene_name": "Tram2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFRRRTKSYPLFSQEFIIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPTADSETVHYHYGPKDLVTILFYVVITIIFHAVVQEYILDKISKRLHLSKVKHSKFNESGQLLVFHLSAVAWCFYVIVTEGYLTNPRSLWEDYPHVYLSFQVKFFYLGQLAYWLHSLPELYFQKVRKEEVPRQLQYICLYLLHITGAYLLNLSRLGLILLLLQYSTEALFHMARLFHFADENNERLFNAWAAVFGVTRLFILTLAVLTIGFGLARVENQVFDPEKGNFNTLPCRLGMLLLVCVAQAWLMWRFIHSQLRHWREYWKEQSAKRRVSAVPRPPAKLLKREPGYHENGVVKAENGTSSRTKKLKSP", "length": 370 }, "evidence": [ { "id": "E1BCM2", "url": "https://omabrowser.org/oma/group/E1BCM2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein insertion into ER membrane", "id": "GO:0045048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045048", "evidence": [ { "database": "UniProtKB", "id": "E1BCM2", "url": "https://www.uniprot.org/uniprotkb/E1BCM2" } ], "pmid": "" }, { "name": "collagen biosynthetic process", "id": "GO:0032964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032964", "evidence": [ { "database": "UniProtKB", "id": "E1BCM2", "url": "https://www.uniprot.org/uniprotkb/E1BCM2" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, translocation", "id": "GO:0006616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006616", "evidence": [ { "database": "UniProtKB", "id": "E1BCM2", "url": "https://www.uniprot.org/uniprotkb/E1BCM2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BCM2", "url": "https://www.uniprot.org/uniprotkb/E1BCM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCM2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 370, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BCM2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BCM2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BCM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCM2" }, { "id": "PS50922", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50922" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TLC", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 321, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BCM7-1", "uniprot_ac": "E1BCM7", "uniprot_id": "E1BCM7_BOVIN", "mass": { "chemical_mass": 39210.0, "monoisotopic_mass": 39210.0 }, "refseq": { "ac": "NP_001179170", "name": "galanin receptor type 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179170" }, "gene_names": [ { "name": "GALR1", "type": "recommended", "evidence": [ { "id": "E1BCM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCM7" } ] }, { "name": "GALR1", "type": "synonym", "evidence": [ { "id": "NP_001179170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179170" } ] } ], "protein_names": [ { "name": "Galanin receptor type 1", "type": "recommended", "evidence": [ { "id": "E1BCM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCM7/entry#names_and_taxonomy" } ] }, { "name": "galanin receptor type 1", "type": "synonym", "evidence": [ { "id": "NP_001179170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179170" } ] } ], "function": [ { "annotation": "Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.", "evidence": [ { "database": "UniProtKB", "id": "E1BCM7", "url": "https://www.uniprot.org/uniprotkb/E1BCM7#function" }, { "database": "UniProtKB", "id": "ARBA00053116", "url": "https://www.uniprot.org/uniprotkb/ARBA00053116#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCM7", "url": "https://www.uniprot.org/uniprotkb/E1BCM7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GALR1", "url": "https://www.uniprot.org/uniprotkb/E1BCM7", "locus": { "chromosome": "24", "start_pos": 2144783, "end_pos": 2157049, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021003", "url": "https://www.ensembl.org/id/ENSBTAG00000021003" } ] } } ], "crossref": [ { "id": "E1BCM7", "url": "https://alphafold.ebi.ac.uk/entry/E1BCM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021003", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021003", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15098", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15098", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539429", "url": "https://www.ncbi.nlm.nih.gov/gene/539429", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539429", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539429", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CWEQWPD", "url": "https://omabrowser.org/oma/group/CWEQWPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCM7", "url": "https://www.orthodb.org/?gene=E1BCM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179170", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179170", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCM7", "url": "https://www.uniprot.org/uniprotkb/E1BCM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCM7-1", "url": "https://www.uniprot.org/uniprotkb/E1BCM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELEVGNFSEGNASGLEPPTPDPRPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSALRVSRNALLGVGFIWALSIAMASPVAYHQRLFHRDVSNQTFCWEQWPNQRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNVSKKSEASKKKTAQTVLVVVVVFGVSWLPHHVIHLWAEFGVFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHARKESPLNDTKENKSRLDTPPSTNCTHV", "length": 349, "header": "tr|E1BCM7-1|E1BCM7_BOVIN Isoform 1 of Galanin receptor type 1 OS=Bos taurus OX=9913 GN=GALR1 PE=3 SV=1 CANONICAL=E1BCM7-1" }, "isoforms": [ { "isoform_ac": "E1BCM7-1", "url": "https://www.uniprot.org/uniprotkb/E1BCM7/entry#E1BCM7-1", "sequence": { "sequence": "MELEVGNFSEGNASGLEPPTPDPRPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSALRVSRNALLGVGFIWALSIAMASPVAYHQRLFHRDVSNQTFCWEQWPNQRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNVSKKSEASKKKTAQTVLVVVVVFGVSWLPHHVIHLWAEFGVFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHARKESPLNDTKENKSRLDTPPSTNCTHV", "length": 349, "header": "tr|E1BCM7-1|E1BCM7_BOVIN Isoform 1 of Galanin receptor type 1 OS=Bos taurus OX=9913 GN=GALR1 PE=3 SV=1 CANONICAL=E1BCM7-1" }, "locus": { "chromosome": "24", "start_pos": 2156850, "end_pos": 2145787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027969.5", "url": "https://www.ensembl.org/id/ENSBTAT00000027969.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027969.3", "url": "https://www.ensembl.org/id/ENSBTAP00000027969.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539429", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539429", "resource": "KEGG Pathway" }, { "id": "R-BTA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-BTA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1U6F0-1", "protein_name": "Galanin receptor type 1", "gene_name": "GALR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELAAGNLSEGNESWPEPPTLEPRPLFGIGVENFITLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLVAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYHQRLFHRGVGNQTFCWEQWPNQHHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGVSWLPHHVIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIGKESPLHDTKENKSRLDTPPSTNCTHV", "length": 349 }, "evidence": [ { "id": "E1BCM7", "url": "https://omabrowser.org/oma/group/E1BCM7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I6F5-1", "protein_name": "Galanin receptor type 1", "gene_name": "Galr1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MELATLNLSEGNEGNGSDPEPPAAVESRLLFGIGVENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFTHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYHQRLYYRDNNQTFCWELWPNQLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVVHLWAEFGAFPLTQASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIHKSVPSDTKENKSRIDTPPSTNCTHV", "length": 351 }, "evidence": [ { "id": "E1BCM7", "url": "https://omabrowser.org/oma/group/E1BCM7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P47211-1", "protein_name": "Galanin receptor type 1", "gene_name": "GALR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV", "length": 349 }, "evidence": [ { "id": "E1BCM7", "url": "https://omabrowser.org/oma/group/E1BCM7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P56479-1", "protein_name": "Galanin receptor type 1", "gene_name": "Galr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELAMVNLSEGNGSDPEPPAPESRPLFGIGVENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYHQRLFHRDSNQTFCWEQWPNKLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVVHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHVCDESPRSETKENKSRMDTPPSTNCTHV", "length": 348 }, "evidence": [ { "id": "E1BCM7", "url": "https://omabrowser.org/oma/group/E1BCM7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62805-1", "protein_name": "Galanin receptor type 1", "gene_name": "Galr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELAPVNLSEGNGSDPEPPAEPRPLFGIGVENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYYQRLFHRDSNQTFCWEHWPNQLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVIHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCRVCNESPHGDAKEKNRIDTPPSTNCTHV", "length": 346 }, "evidence": [ { "id": "E1BCM7", "url": "https://omabrowser.org/oma/group/E1BCM7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BCM7", "url": "https://www.uniprot.org/uniprotkb/E1BCM7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "E1BCM7", "url": "https://www.uniprot.org/uniprotkb/E1BCM7" } ], "pmid": "" }, { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "E1BCM7", "url": "https://www.uniprot.org/uniprotkb/E1BCM7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BCM7", "url": "https://www.uniprot.org/uniprotkb/E1BCM7" } ], "pmid": "" }, { "name": "positive regulation of cortisol secretion", "id": "GO:0051464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051464", "evidence": [ { "database": "UniProtKB", "id": "E1BCM7", "url": "https://www.uniprot.org/uniprotkb/E1BCM7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "E1BCM7", "url": "https://www.uniprot.org/uniprotkb/E1BCM7" } ], "pmid": "" }, { "name": "galanin receptor activity", "id": "GO:0004966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004966", "evidence": [ { "database": "UniProtKB", "id": "E1BCM7", "url": "https://www.uniprot.org/uniprotkb/E1BCM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCM7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 349, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BCM7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BCM7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BCM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCM7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 303, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 76, "end_pos": 78 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BCN2-1", "uniprot_ac": "E1BCN2", "uniprot_id": "E1BCN2_BOVIN", "mass": { "chemical_mass": 45440.0, "monoisotopic_mass": 45440.0 }, "refseq": { "ac": "NP_001193168", "name": "cobalamin binding intrinsic factor precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193168" }, "gene_names": [ { "name": "CBLIF", "type": "recommended", "evidence": [ { "id": "E1BCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCN2" } ] }, { "name": "CBLIF", "type": "synonym", "evidence": [ { "id": "NP_001193168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193168" } ] }, { "name": "GIF", "type": "synonym", "evidence": [ { "id": "NP_001193168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193168" } ] } ], "protein_names": [ { "name": "Cobalamin binding intrinsic factor", "type": "synonym", "evidence": [ { "id": "E1BCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCN2/entry#names_and_taxonomy" } ] }, { "name": "cobalamin binding intrinsic factor precursor", "type": "synonym", "evidence": [ { "id": "NP_001193168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193168" } ] }, { "name": "gastric intrinsic factor (vitamin B synthesis)", "type": "synonym", "evidence": [ { "id": "NP_001193168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193168" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCN2", "url": "https://www.uniprot.org/uniprotkb/E1BCN2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CBLIF", "url": "https://www.uniprot.org/uniprotkb/E1BCN2", "locus": { "chromosome": "15", "start_pos": 83029815, "end_pos": 83048887, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012057", "url": "https://www.ensembl.org/id/ENSBTAG00000012057" } ] } } ], "crossref": [ { "id": "E1BCN2", "url": "https://alphafold.ebi.ac.uk/entry/E1BCN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012057", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012057", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "616252", "url": "https://www.ncbi.nlm.nih.gov/gene/616252", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616252", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616252", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYNVEAQ", "url": "https://omabrowser.org/oma/group/AYNVEAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCN2", "url": "https://www.orthodb.org/?gene=E1BCN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10559:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10559:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01122", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01122", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9758881", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9758881", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193168", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193168", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCN2", "url": "https://www.uniprot.org/uniprotkb/E1BCN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCN2-1", "url": "https://www.uniprot.org/uniprotkb/E1BCN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARAALQLLTLLWAATRTSTQTRSSCSVPSAEQPWVDGIQVIMENSVINSTSPNPSVLIAMNLAGAYNVEAQKLLTFDLMASDTADLTAGQLALTIMALTSSCRDPGDKVSTLRTQMENWTPSSLGSYASTFYGPSLAILALCQNNPETTLPVAARFAKTLLASSSPFDVDAGAVATLALTCMYNRIPVGSEEGYRALFAQLLKKIVEDISTRIRDNGLIGDVYSTGLAMQALSVTPERPNKQWDCQQTMDTVLDEIKEGKFQNSMSIAQILPSLKGKTYLDVPQVSCSPDQEVQPTQPNFPSPVPTSASNITVVYTISNQLRGVELLFNVTISVSVKKGSVLLVVLEEAQRRNPKFKFETRMTSWGLEVSSINNIAGNVNDKTYWQFLSGKTPLIEGVADYIPFNHEHITANFTQY", "length": 417, "header": "tr|E1BCN2-1|E1BCN2_BOVIN Isoform 1 of Cobalamin binding intrinsic factor OS=Bos taurus OX=9913 GN=CBLIF PE=3 SV=1 CANONICAL=E1BCN2-1" }, "isoforms": [ { "isoform_ac": "E1BCN2-1", "url": "https://www.uniprot.org/uniprotkb/E1BCN2/entry#E1BCN2-1", "sequence": { "sequence": "MARAALQLLTLLWAATRTSTQTRSSCSVPSAEQPWVDGIQVIMENSVINSTSPNPSVLIAMNLAGAYNVEAQKLLTFDLMASDTADLTAGQLALTIMALTSSCRDPGDKVSTLRTQMENWTPSSLGSYASTFYGPSLAILALCQNNPETTLPVAARFAKTLLASSSPFDVDAGAVATLALTCMYNRIPVGSEEGYRALFAQLLKKIVEDISTRIRDNGLIGDVYSTGLAMQALSVTPERPNKQWDCQQTMDTVLDEIKEGKFQNSMSIAQILPSLKGKTYLDVPQVSCSPDQEVQPTQPNFPSPVPTSASNITVVYTISNQLRGVELLFNVTISVSVKKGSVLLVVLEEAQRRNPKFKFETRMTSWGLEVSSINNIAGNVNDKTYWQFLSGKTPLIEGVADYIPFNHEHITANFTQY", "length": 417, "header": "tr|E1BCN2-1|E1BCN2_BOVIN Isoform 1 of Cobalamin binding intrinsic factor OS=Bos taurus OX=9913 GN=CBLIF PE=3 SV=1 CANONICAL=E1BCN2-1" }, "locus": { "chromosome": "15", "start_pos": 83048849, "end_pos": 83029991, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015993.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015993.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015993.4", "url": "https://www.ensembl.org/id/ENSBTAP00000015993.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616252", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616252", "resource": "KEGG Pathway" }, { "id": "R-BTA-9758881", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9758881", "resource": "Reactome", "description": "Uptake of dietary cobalamins into enterocytes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1ENZ1-1", "protein_name": "Cobalamin binding intrinsic factor", "gene_name": "CBLIF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDSTGESGMARAALQLLTLLWAVAGTSTQTRSSCSVPSAEQPLVNGIQVLMEQSVTSSAFPNPSILIAMNLAGAYNTEAQELLTYKLMASNTSDLTTGQLALTIMALTSSCRDPGNRIAILQGQMENWAPPSLDTHASTFYEPSLGILTLCQNNPEKTLPLAARFAKTLLANSSPFNMDTGAMATLALTCMYNKIPVGSEEGYRALFSQVLRNTVENISMRIQDNGIIGNIYSTGLAMQALSVTPERPNKEWDCQKTMDTVLTEIKEGKFHNPMAIAQILPSLKGKTYLDVPHVSCSPGHEVPPTLPNHPSPVPTPAPNITVIYTINNQLRGVELLFNETISVSVKRGSVLLIVLEEAQRKNPKFKFETTMTSWGPVVSSINNIAENVNHRTYWQFLSGQTPLNEGVADYIPFNHEHITANFTQY", "length": 425 }, "evidence": [ { "id": "E1BCN2", "url": "https://omabrowser.org/oma/group/E1BCN2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1A3I6-1", "protein_name": "DUF4430 domain-containing protein", "gene_name": "CBLIF", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQRQRGTAGTEVLRMLGVALSTAVLLALAGCGAEGTDPQNCTVSAEERARMLGILQLSAMDSGTPNPSVLLALNLAGDSSKARQELLERIKETAAKQAKDMSSGQVALYTLALRSSCCDPRDVAAHGQSVDLLSILQEKTDQELTHLEQNGTPKSSLFSVGLDAQALCVTGAGDYESAATILAKQLQRSQDKLSVDEQAMMALALVCAYNRTEHKDVQDLLNRTLTMVSNGFLDKQAEGNGIIGNIYSTGLAMQLLLAAGKFYAPRPWDCTQPVAAITAQHLQQPMAVAQALPALVGRTYLDSASLDCSPEAPTTAGMQLDTVLTKGTTPEQAGSNITVNYTITNEVRGKHFSYSTEVEVPAGSVLLVVLEEAQKSNKTIFSFKTESTFWGPMVVSIHGLAASENDRTFWQFFNGSVPLQEGGQCWGAGRGCAGEPQPHSRSPLQGLAHTNHRMGSTSGLSSASTDGTGEQQPCWALQRGNKESFAARPPLCALTALGPTPPLCVSVTFEVPSKPTPLLSCDPCGSLPRCDILQFHVPTHGLGAAGAARGEGGRAEDSARQRGPGTHIPFPSAEGEGVDA", "length": 580 }, "evidence": [ { "id": "E1BCN2", "url": "https://omabrowser.org/oma/group/E1BCN2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P17267-1", "protein_name": "Cobalamin binding intrinsic factor", "gene_name": "Cblif", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWLSFYLLNVLWAVAGTSTRAQRSCSVPPDQQPWVNGLQLLMENSVTESDLPNPSILIAMNLASTYNLEAQKLLTYQLMASDSADLTNGQLALTIMALTSSCRDPGSKVSILQKNMESWTPSNLGAESSSFYGPALAILALCQKNSEATLPIAVRFAKTLMMESSPFSVDTGAVATLALTCMYNRIPVGSQENYRDLFGQALKVIVDNISLRIKADGIIGDIYSTGLAMQALSVTPEQPTKEWDCEKTMYTILKEIKQGKFQNPMSIAQILPSLKGKTYLDVPQVTCGPDHEVPPTLTDYPTPVPTSISNITVIYTINNQLRGVDLLFNVTIEVSVKSGSVLLAVLEEAQRRNHMFKFETTMTSWGLIVSSINNIAENVKHKTYWEFLSGKTPLGEGVAYYIPFNYEHITANFTQY", "length": 417 }, "evidence": [ { "id": "E1BCN2", "url": "https://omabrowser.org/oma/group/E1BCN2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P27352-1", "protein_name": "Cobalamin binding intrinsic factor", "gene_name": "CBLIF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAWFALYLLSLLWATAGTSTQTQSSCSVPSAQEPLVNGIQVLMENSVTSSAYPNPSILIAMNLAGAYNLKAQKLLTYQLMSSDNNDLTIGQLGLTIMALTSSCRDPGDKVSILQRQMENWAPSSPNAEASAFYGPSLAILALCQKNSEATLPIAVRFAKTLLANSSPFNVDTGAMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDNGIIGDIYSTGLAMQALSVTPEPSKKEWNCKKTTDMILNEIKQGKFHNPMSIAQILPSLKGKTYLDVPQVTCSPDHEVQPTLPSNPGPGPTSASNITVIYTINNQLRGVELLFNETINVSVKSGSVLLVVLEEAQRKNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFLSGVTPLNEGVADYIPFNHEHITANFTQY", "length": 417 }, "evidence": [ { "id": "E1BCN2", "url": "https://omabrowser.org/oma/group/E1BCN2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P52787-1", "protein_name": "Cobalamin binding intrinsic factor", "gene_name": "Cblif", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWLTLYLLSVLWAVAGTSTRAQSSCSVPPDQQPWVDGLQALMENSVTDSDFPNPSILIAMNLAGAYNVEAQKLLTYQLMASDSADLTSGQLALTVMALTSSCRDPGSKVSTLLKKMENWSPSSPGAESSAFYGPGLAILALCQKSSEATLPIAVRFAKTLMMEPSPFNVDTGAVATLALTCMYNKIPVGSQENYRDLFGQALKAIVEKISLRIKADGIIGDIYSTGLAMQALSVTPEQPTKKWDCEKTMHTILNEIKQGKFQNPMSIAQILPSLKGKTYLDVPQVTCGPDHEVPPTLTDYPTPVPTSVSNITVIYTINNQLRGVDLLFNVTIEVSVKSGSVLLAVLEEAQRKNSMFKFETTMTSWGLIVSSINNIAENVNHKTYWEFLSGKTPLDEGVAYYIPFNHEHITANFTQY", "length": 417 }, "evidence": [ { "id": "E1BCN2", "url": "https://omabrowser.org/oma/group/E1BCN2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BCN2", "url": "https://www.uniprot.org/uniprotkb/E1BCN2" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "E1BCN2", "url": "https://www.uniprot.org/uniprotkb/E1BCN2" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "E1BCN2", "url": "https://www.uniprot.org/uniprotkb/E1BCN2" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "E1BCN2", "url": "https://www.uniprot.org/uniprotkb/E1BCN2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cobalamin transport", "id": "GO:0015889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015889", "evidence": [ { "database": "UniProtKB", "id": "E1BCN2", "url": "https://www.uniprot.org/uniprotkb/E1BCN2" } ], "pmid": "" }, { "name": "cobalt ion transport", "id": "GO:0006824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006824", "evidence": [ { "database": "UniProtKB", "id": "E1BCN2", "url": "https://www.uniprot.org/uniprotkb/E1BCN2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cobalamin binding", "id": "GO:0031419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031419", "evidence": [ { "database": "UniProtKB", "id": "E1BCN2", "url": "https://www.uniprot.org/uniprotkb/E1BCN2" } ], "pmid": "" }, { "name": "cargo receptor ligand activity", "id": "GO:0140355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140355", "evidence": [ { "database": "UniProtKB", "id": "E1BCN2", "url": "https://www.uniprot.org/uniprotkb/E1BCN2" } ], "pmid": "" }, { "name": "molecular carrier activity", "id": "GO:0140104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140104", "evidence": [ { "database": "UniProtKB", "id": "E1BCN2", "url": "https://www.uniprot.org/uniprotkb/E1BCN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCN2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 417, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BCN2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BCN2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 311, "end_pos": 313 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BCR0-1", "uniprot_ac": "E1BCR0", "uniprot_id": "E1BCR0_BOVIN", "mass": { "chemical_mass": 68633.0, "monoisotopic_mass": 68633.0 }, "refseq": { "ac": "NP_001192841", "name": "SHC-transforming protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192841" }, "gene_names": [ { "name": "SHC4", "type": "recommended", "evidence": [ { "id": "E1BCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCR0" } ] }, { "name": "SHC4", "type": "synonym", "evidence": [ { "id": "NP_001192841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192841" } ] } ], "protein_names": [ { "name": "SHC (Src homology 2 domain containing) family, member 4", "type": "synonym", "evidence": [ { "id": "NP_001192841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192841" } ] }, { "name": "SHC adaptor protein 4", "type": "synonym", "evidence": [ { "id": "E1BCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCR0/entry#names_and_taxonomy" } ] }, { "name": "SHC-transforming protein 4", "type": "synonym", "evidence": [ { "id": "NP_001192841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192841" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCR0", "url": "https://www.uniprot.org/uniprotkb/E1BCR0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SHC4", "url": "https://www.uniprot.org/uniprotkb/E1BCR0", "locus": { "chromosome": "10", "start_pos": 61419640, "end_pos": 61284302, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000022583", "url": "https://www.ensembl.org/id/ENSBTAG00000022583" } ] } } ], "crossref": [ { "id": "E1BCR0", "url": "https://alphafold.ebi.ac.uk/entry/E1BCR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000022583", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000022583", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01209", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01209", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09925", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09925", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "524734", "url": "https://www.ncbi.nlm.nih.gov/gene/524734", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524734", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524734", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNIDNQQ", "url": "https://omabrowser.org/oma/group/MNIDNQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCR0", "url": "https://www.orthodb.org/?gene=E1BCR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10337:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10337:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192841", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192841", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCR0", "url": "https://www.uniprot.org/uniprotkb/E1BCR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCR0-1", "url": "https://www.uniprot.org/uniprotkb/E1BCR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRERGQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLDEGSPGVSTGSKGSPQPPYPTLAPHLPAEDAALASQESPTPLCTLIPRMASVKLANPATLLSLKNFCLGTKEVPRLKLQESQDPAPSSPASPETSLNRAVPAPPPQRDPLGHRATSLTPDACPLPGPGEPTPRNRQDRHFVQHLLGLGMNYYVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRKPPAKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECRNGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEVPVDGHAEEREDHEYYNEIPGKQPPAGGVSDVRIKVQVTEQMAYCPIRCEKLCYLPGSSKSSSMYENCLEQSRAIGNAHERGVPSQREASLMKHSCGADLFDDPCYINTQALRSTLGPAGNQSSPHPLGSPWPQETAPETVQPGATAQPASSHSLPHIKQQLRNEDCYHGKLSRKAAESLLVKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDNSLPIISSGSEVSLKQPVRKDNNPGLLHSNK", "length": 630, "header": "tr|E1BCR0-1|E1BCR0_BOVIN Isoform 1 of SHC adaptor protein 4 OS=Bos taurus OX=9913 GN=SHC4 PE=4 SV=3 CANONICAL=E1BCR0-1" }, "isoforms": [ { "isoform_ac": "E1BCR0-1", "url": "https://www.uniprot.org/uniprotkb/E1BCR0/entry#E1BCR0-1", "sequence": { "sequence": "MRERGQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLDEGSPGVSTGSKGSPQPPYPTLAPHLPAEDAALASQESPTPLCTLIPRMASVKLANPATLLSLKNFCLGTKEVPRLKLQESQDPAPSSPASPETSLNRAVPAPPPQRDPLGHRATSLTPDACPLPGPGEPTPRNRQDRHFVQHLLGLGMNYYVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRKPPAKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECRNGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEVPVDGHAEEREDHEYYNEIPGKQPPAGGVSDVRIKVQVTEQMAYCPIRCEKLCYLPGSSKSSSMYENCLEQSRAIGNAHERGVPSQREASLMKHSCGADLFDDPCYINTQALRSTLGPAGNQSSPHPLGSPWPQETAPETVQPGATAQPASSHSLPHIKQQLRNEDCYHGKLSRKAAESLLVKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDNSLPIISSGSEVSLKQPVRKDNNPGLLHSNK", "length": 630, "header": "tr|E1BCR0-1|E1BCR0_BOVIN Isoform 1 of SHC adaptor protein 4 OS=Bos taurus OX=9913 GN=SHC4 PE=4 SV=3 CANONICAL=E1BCR0-1" }, "locus": { "chromosome": "10", "start_pos": 61418636, "end_pos": 61284501, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015489.8", "url": "https://www.ensembl.org/id/ENSBTAT00000015489.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015489.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015489.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 172, "start_aa": "Thr", "end_pos": 172, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr172", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:524734", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524734", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LD01-1", "protein_name": "SHC-transforming protein 4 isoform X2", "gene_name": "Shc4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRERGQDGQAGLALYVGLFGHLGMLHRAKYSRFRNESITSLDEGSSGGSVGNKGSSPPPYPALAPHLPAEDATVPTQESPTALCTLIPRMASMKLANPVTFLSLKTFCLGTKEVPRLKLQESQDQATSSPASPETSLNRTGPAPTPHPHLHPDQVGRRTTPLSPDACPLPGPGQPIPRSRQDKHSPQHLLGSGLNYCVRYMGCIEVLKSMRSLDFGMRTQVTREAISRLCDAVPGAHGAIKKRKAPVKFLSAVLGKSNLQFSGMNIKLTVSTCSLTLMNLDNQQIIAKHQMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECHSGMAQDVISTIGQAFELRFKQYLKNPSVNTWESEEVRVEGTSEDRDHAYYNAMPRKLPPAGGISDVRIRVQATDQMAYCPIRCEKLCYLPVNSKCRGVYENCTGQRGSIGIPHQRGMHGDAALMKHACRVDLFDDPCYVNTQALQSTRGYAANQSSIQPHGSTWHIGKAPETVQPGARAQSMSSYSLPHIKQQLWSEECFHGRLSRGAAERLLVKDGDFLVRESMTSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIKYHMDNSLPIISSGSEVSLKQPVRKDNNTRLLHYKK", "length": 630 }, "evidence": [ { "id": "E1BCR0", "url": "https://omabrowser.org/oma/group/E1BCR0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0ZBZ6-1", "protein_name": "SHC adaptor protein 4", "gene_name": "SHC4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLHRAKYSRFRNDSVTSLDEGPQNIKGSSSSSHPSAPNLLAEDVPLGPQDACTTLCALIPRVANIKLANPSALPSLKGFCLGSKEVPRTKLTECVAVPGGPSSPELGCLSASYPQPGPEGPHLTPRPAGGCTGRGAAEAVSRLGGSLVTSGESAEEPGTTYSVRYMGCIEVLQSMRSLDFGTRTQVTREAISRLCEAVSGTNGAIRKRKPPVKFLSSVLGKSNLQFSGVNIKLTISTNSLTLINVDTQQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECPNGMAQEVINTIGQAFELRFKQYLKNPSSLVTSNESEAVSADGSAGNLQEREDHEYYNEIPGKEPPAGGVLDMRMKVPTDQRSGCFIQCKKQHCLTGSPTFINIYENCPEENKTVGPCAERSQKTKKDATLLKSAYRTDLFDDPCYINTQALQSAVCTARGTAATQIHGSPRSHTKLPETVQQSATSNTAGLCVLPQIKQQLRNEDCYHGKLNRKAAESLLVNDGDFLVRESTTSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDRIFDSVGHLIQYHMENNLPIISSGSEVSLKQPVRKESNMGHLHYHK", "length": 602 }, "evidence": [ { "id": "E1BCR0", "url": "https://omabrowser.org/oma/group/E1BCR0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A3K2-1", "protein_name": "SHC adaptor protein 4", "gene_name": "Shc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRERSQDSQAGLTLYVGLFGHLGMLHRTKYSRFRNESITSLDEGSPGGSVGNKGSSPPPYAALTPHLPAEDATVPNQESPTALCTLIPRMASMKLANPVTFLSLKTFCLGSKQVPRLKLQENQDQTPSSPASPETSLNSTGPAPTPLPDQVGCRPTSLRPDTCPLPGPGEPNPRSKQDGPPLQHLLGNGLNYCVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGVHGAIKKRKAPVKFLTTVLGKSNLQFSGMNIKLTVSTSSLTLMNLDNQQIIANHQMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECRSGTAQDIISTIGQAFELRFKQYLKNPSLNTWEREEVLVDGTSEDRGHDYYNSIPGKQPPAGGIADVRIQVQADPVAYCPIRCEKLCYLPGTSTCSGVYKNCMGRSRPIGIPHERAMQSDAASLRHFWRVDLFDDPCYVNTQNMRGCAGNQSSTLPQGSPWHLGKAPETVQPGATAKPGSSHALPHIKQQLWSEECFHGRLSRGAAERLLVKDGDFLVRESVTSPGQFVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIKYHMDNSLPIISSGSEVSLKQPVKKHNNPGLSHSKK", "length": 622 }, "evidence": [ { "id": "E1BCR0", "url": "https://omabrowser.org/oma/group/E1BCR0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6S5L8-1", "protein_name": "SHC-transforming protein 4", "gene_name": "SHC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRERGQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLDEGSSGGSVGNKGSPQPPHPALAPHLPTEDATLPSQESPTPLCTLIPRMASMKLANPATLLSLKNFCLGTKEVPRLKLQESRDPGSSGPSSPETSLSRSGTAPPPQQDLVGHRATALTPDSCPLPGPGEPTLRSRQDRHFLQHLLGMGMNYCVRYMGCVEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRKPPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECHNGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEVHIDSHAEEREDHEYYNEIPGKQPPVGGVSDMRIKVQATEQMAYCPIQCEKLCYLPGNSKCSSVYENCLEQSRAIGNVHPRGVQSQRDTSLLKHTCRVDLFDDPCYINTQALQSTPGSAGNQRSAQPLGSPWHCGKAPETVQPGATAQPASSHSLPHIKQQLWSEECYHGKLSRKAAESLLVKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDNSLPIISSGSEVSLKQPVRKDNNPALLHSNK", "length": 630 }, "evidence": [ { "id": "E1BCR0", "url": "https://omabrowser.org/oma/group/E1BCR0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6S5L9-1", "protein_name": "SHC-transforming protein 4", "gene_name": "Shc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRERSQDSQAGLTLYVGLFGHLGMLHRTKYSRFRNESITSLDEGSPGGSVGNKGSSPPPYPALAPHLPTEDATVSSQESPTALCTLIPRMASMKLANPITFLGLKTFCLGTKQVSRLKLQENQDQTPSRPASPESNLNRTGPAPAPDPDQVGRRPTSLRPDTCPLPGPGEPSPRSKQDGPPLQHLLGNGLNYCVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGAHGAIKKRKAPVKFLTTVLGKSNLQFSGMNIKLTVSTSSLTLMNLDNQQIIANHQMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECRSGMAQDVISTIGQAFELRFKQYLKNPSLNTWEREEVLVDGAPEDRDHDYYNSIPGKQPPEGGISDVRIQAQATDQMAYCPIRCEKLCYLPGNSTCSGVYKNCMGRSRPIGIPHERAGQGDTPSLRHFWRVDLFDDPCYVNTQALQSMHSYAGNQSSALPQGSPWHLGKAPETVQPGATAKPGSALALPHIRQQLWDEECFHGKLSRGAAEKLLVKDGDFLVRESVTSPGQFVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIKYHMDNNLPIISSGSEVRLKQPIRKYDNTGLLPPKK", "length": 626 }, "evidence": [ { "id": "E1BCR0", "url": "https://omabrowser.org/oma/group/E1BCR0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BCR0", "url": "https://www.uniprot.org/uniprotkb/E1BCR0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "E1BCR0", "url": "https://www.uniprot.org/uniprotkb/E1BCR0" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BCR0", "url": "https://www.uniprot.org/uniprotkb/E1BCR0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "E1BCR0", "url": "https://www.uniprot.org/uniprotkb/E1BCR0" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "E1BCR0", "url": "https://www.uniprot.org/uniprotkb/E1BCR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCR0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 630, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BCR0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BCR0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCR0" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 189, "end_pos": 349, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCR0" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 526, "end_pos": 617, "start_aa": "Cys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 172 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 352, "end_pos": 354 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 480, "end_pos": 482 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BCS0-1", "uniprot_ac": "E1BCS0", "uniprot_id": "E1BCS0_BOVIN", "mass": { "chemical_mass": 83582.0, "monoisotopic_mass": 83582.0 }, "refseq": { "ac": "NP_001179214", "name": "zinc finger protein 366", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179214" }, "gene_names": [ { "name": "ZNF366", "type": "recommended", "evidence": [ { "id": "E1BCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ] }, { "name": "ZNF366", "type": "synonym", "evidence": [ { "id": "NP_001179214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179214" } ] } ], "protein_names": [ { "name": "Zinc finger protein 366", "type": "recommended", "evidence": [ { "id": "E1BCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCS0/entry#names_and_taxonomy" } ] }, { "name": "Dendritic cell-specific transcript protein", "type": "synonym", "evidence": [ { "id": "E1BCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCS0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 366", "type": "synonym", "evidence": [ { "id": "NP_001179214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179214" } ] } ], "function": [ { "annotation": "Has transcriptional repression activity. Acts as a corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases.", "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0#function" }, { "database": "UniProtKB", "id": "ARBA00058623", "url": "https://www.uniprot.org/uniprotkb/ARBA00058623#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF366", "url": "https://www.uniprot.org/uniprotkb/E1BCS0", "locus": { "chromosome": "20", "start_pos": 9174870, "end_pos": 9113066, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020601", "url": "https://www.ensembl.org/id/ENSBTAG00000020601" } ] } } ], "crossref": [ { "id": "E1BCS0", "url": "https://alphafold.ebi.ac.uk/entry/E1BCS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020601", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020601", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539632", "url": "https://www.ncbi.nlm.nih.gov/gene/539632", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539632", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539632", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKHRNKS", "url": "https://omabrowser.org/oma/group/FKHRNKS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCS0", "url": "https://www.orthodb.org/?gene=E1BCS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179214", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179214", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCS0-1", "url": "https://www.uniprot.org/uniprotkb/E1BCS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQKELKMVKDEDVHFSLGVKRAPSFPHGLQPVVSRGKAPPGHPFPEALRGPFSQFRYEPPPGELDGYPGVFEGGGSRKRKSMPTKMPYNHPAEEGALGLHPEESKNPGVPDLPLLFPPPPPPRPKYDSRMIDLCNVGFQFYRSLEHLGGKAVKQEPVKPSAVWPAPAAPPFLPAPYPYYPKVAPGLVFPFFVPSASPFPFSRHTFLPKRPPEPPLPRKAEPPESEETKQKVERVDVNVQIDDSYYVDVGGAQKRWQCPTCEKSYTSKYNLVTHILGHSGIKPHACSRCGKLFKQLSHLHTHMLTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSEVKPHNCRVCGRGFAYPSELKAHEAKHASGRENICVECGLDFPTLAQLKRHLTTHRGPIQYNCSECDKTFQYPSQLQNHMMKHKDIRPYICSECGMEFVQPHHLKQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCYKSFVQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHMHLHSDSKPFKCLYCPSKFTLKGNLTRHMKVKHGVMERGLHSQGFGRGRIALAPTAGALRSLEQEEPFDLSQKRRAKGPAFQSDGESARGSSCHEEEDEDNCYEVEPDSPGLGPRGPPLCAPRDLSAKPEPGPGEEAPAEEASPPGARPLKSRDSLGPEGGPEREFARRDERPGLRVLPSTRRGPAFSDYLYFKHRDESLKELLERKMEKQAVLLGI", "length": 742, "header": "tr|E1BCS0-1|E1BCS0_BOVIN Isoform 1 of Zinc finger protein 366 OS=Bos taurus OX=9913 GN=ZNF366 PE=4 SV=1 CANONICAL=E1BCS0-1" }, "isoforms": [ { "isoform_ac": "E1BCS0-1", "url": "https://www.uniprot.org/uniprotkb/E1BCS0/entry#E1BCS0-1", "sequence": { "sequence": "MQKELKMVKDEDVHFSLGVKRAPSFPHGLQPVVSRGKAPPGHPFPEALRGPFSQFRYEPPPGELDGYPGVFEGGGSRKRKSMPTKMPYNHPAEEGALGLHPEESKNPGVPDLPLLFPPPPPPRPKYDSRMIDLCNVGFQFYRSLEHLGGKAVKQEPVKPSAVWPAPAAPPFLPAPYPYYPKVAPGLVFPFFVPSASPFPFSRHTFLPKRPPEPPLPRKAEPPESEETKQKVERVDVNVQIDDSYYVDVGGAQKRWQCPTCEKSYTSKYNLVTHILGHSGIKPHACSRCGKLFKQLSHLHTHMLTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSEVKPHNCRVCGRGFAYPSELKAHEAKHASGRENICVECGLDFPTLAQLKRHLTTHRGPIQYNCSECDKTFQYPSQLQNHMMKHKDIRPYICSECGMEFVQPHHLKQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCYKSFVQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHMHLHSDSKPFKCLYCPSKFTLKGNLTRHMKVKHGVMERGLHSQGFGRGRIALAPTAGALRSLEQEEPFDLSQKRRAKGPAFQSDGESARGSSCHEEEDEDNCYEVEPDSPGLGPRGPPLCAPRDLSAKPEPGPGEEAPAEEASPPGARPLKSRDSLGPEGGPEREFARRDERPGLRVLPSTRRGPAFSDYLYFKHRDESLKELLERKMEKQAVLLGI", "length": 742, "header": "tr|E1BCS0-1|E1BCS0_BOVIN Isoform 1 of Zinc finger protein 366 OS=Bos taurus OX=9913 GN=ZNF366 PE=4 SV=1 CANONICAL=E1BCS0-1" }, "locus": { "chromosome": "20", "start_pos": 9173866, "end_pos": 9155376, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027448.4", "url": "https://www.ensembl.org/id/ENSBTAT00000027448.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027448.2", "url": "https://www.ensembl.org/id/ENSBTAP00000027448.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539632", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539632", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y792-1", "protein_name": "Zinc finger protein 366", "gene_name": "ZNF366", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLTVKAIKGIKKEVNMMKNEDANCSVDNTQASPFSHCLQPLSPVTKAHRTTHFGEEFRQHLSHFRYGPPPLGDMESFQGSLEGGSRKRKSMPTKMPPSIALEGSSSPPHRPEDHNDIDSSSLPMAFQQPAQPKYSSQMIDLCNFGFQFYRSLEPFGAKSIKQEPVKPNLAWPSSPAFVQAPYPYYPKVHPGLMFPFIMPPNLHFRNPFQMKRPPEPPFRRAEVRESGENKQKVERVDVNLQIDDSYYVDVGGEQKRWQCPMCEKSYTSKYNLVTHILGHSGIKPHACNRCGKLFKQLSHLHTHMLTHQGTRPHKCQVCHKSFTQTSHLKRHMMQHSDIKPYNCRICGRGFAYPSELKAHESKHESGRENICVECGLDFPTLAQLKRHLTTHRGPIQYNCTECDKTFQYPSQLQNHMMKHKDIRPYICTECGMEFVQPHHLKQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCFKSFVQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHMHLHSDSKPFKCLYCPSKFTLKGNLTRHMKVKHGVMERGFHSQGFGRGRIALSQTNVLRSLEQEEPFDLSQKSQGKGISFHSDGESAKGSSCQEEEEDNCYEAEQYSPGVYHHDSNKLYVPQDLSGKPQCMMKGFRESYCSEKEEILSEEGLEKRVGDSNNQESPGERDLANDKEHLSFRAFEKASLGHSLSDYLYFKHRSKSLKELLERKMEKQTMLIGI", "length": 748 }, "evidence": [ { "id": "E1BCS0", "url": "https://omabrowser.org/oma/group/E1BCS0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A715-1", "protein_name": "Zinc finger protein 366", "gene_name": "Zfp366", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQKVMKMVKDEDGPLNAAAKSIPSFPHCLQPEASRGKAPQRHPFPEALRGPFSQFRYEPSPGDLDGFPEVFEGGGSRKRKSMPTKVPYNHSAEEATIAQESKSLGPPNLALLFPQPQHPKCDSQMIDLCNVGLQFYRTLEHLGGKPVKQEPVKPSAMWPQPTPPAFLPAPYPYYPKVHPGLMFPFFMPSSSPFPFSRHTFLPKQPPEPVLPRKVEPLESEETKQKVERVDVNVQIDDSYYVDVGGAQKRWQCPTCDKSYTSKYNLVTHILGHSGIKPHACSRCGKLFKQLSHLHTHMLTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSEVKPHNCRVCSRGFAYPSELKAHEAKHASGRENICVECGLDFPTLAQLKRHLTTHRGPIQYNCSECDKTFQYPSQLQNHMMKHKDIRPYICSECGMEFVQPHHLKQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCYKSFVQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHLHLHSDSKPFKCLYCPSKFTLKGNLTRHMKVKHGVMERGLHSQGLGRGRLVLAQSTGALRNLEQEEPFDLSQKRSAKGPMFQSDMDSTQGCLYPEEEEEEEEEADEEDKCYDVEPYSPTLALESQQLCAPEDLSTKQEQAPKGPGEGCQDQDTPEEPQEDSSEDHESRDIDCEVRDERLSSRLLQSGGQGPSFSDYLYFKHRDEGLKELLERKMEKQAVLLGI", "length": 743 }, "evidence": [ { "id": "E1BCS0", "url": "https://omabrowser.org/oma/group/E1BCS0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SK10-1", "protein_name": "Zinc finger protein 366", "gene_name": "ZNF366", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQKEMKMVKDEDVHFSLGVKAAPSFPHGLQPVVSRGKAPARHPFPEALRGPFSQFRYEPPPGDLDGFPGVFEGGGSRKRKSMPTKMPYSHPAEEAALALHPEGSKHPGRPDLPLLFPQPPRPKYDSRMIDLCNVGFQFYRSLEHLGSKAVKQEPVKPSALWPPPTPPPFLPTPYPYYPKVPPGLMFPFFVPSASPFPFSRHTFLPKQPPEPPQARKAEPRESEETKQKVERVDVNVQIDDSYYVDVGGAQKRWQCPTCEKSYTSKYNLVTHILGHSGIKPHACSRCGKLFKQLSHLHTHMLTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSEVKPHNCRVCGRGFAYPSELKAHEAKHASGRENICVECGLDFPTLAQLKRHLTTHRGPIQYSCSECDKTFQYPSQLQNHMMKHKDIRPYICSECGMEFVQPHHLKQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCYKSFVQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHMHLHSDSKPFKCLYCPSKFTLKGNLTRHMKVKHGVMERGLQSQGFGRGRLSLAQTAGGLRSLEQEEPFDLSQKRGAKGPASQSDGESARGSSCHEEEDDDHCYEAERDSPGLGPCSPPLCAPQDLSAKPAPGPREEAQAEEDAPQGDRQLQSRDSPGPERGQDRELAGRDECPGFRALQSARRGPSFSDYLYFKHRDESLKELLERKMEKQAVLLGI", "length": 740 }, "evidence": [ { "id": "E1BCS0", "url": "https://omabrowser.org/oma/group/E1BCS0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6NS86-1", "protein_name": "Zinc finger protein 366", "gene_name": "Znf366", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQKAMKMVKDEDGPLNAAAKSIPSFPHCLQPEASRGKAPQRHPFPEALRGPFSQFRYEPSPGDLDGFPEVFEGGGSRKRKSMPTKVPYTHPAEEASIAQESKSLGPPNLTLLFPQPQRPKCDSQMIDLCNVGLQFYRTLEHLGGKPVKQEPVKPSAMWPQPTPPAFLPAPYPYYPKVHPGLMFPFFVPSSSPFPFSRHTFLPKQPPEPVLPRKVEPLESEETKQKVERVDVNVQIDDSYYVDVGGAQKRWQCPTCEKSYTSKYNLVTHILGHSGIKPHACSRCGKLFKQLSHLHTHMLTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSEVKPHNCRVCSRGFAYPSELKAHEAKHASGRENICVECGLDFPTLAQLKRHLTTHRGPIQYNCSECDKTFQYPSQLQNHMMKHKDIRPYICSECGMEFVQPHHLKQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCYKSFVQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHLHLHSDSKPFKCLYCPSKFTLKGNLTRHMKVKHGVMERGLHSQGLGRGRLVLVQSAGVLRNLEQEEPFDLSQKRSANGPMFQSDVDSTQDCLCQEEEEEAGEEDNCYEVEPYSPSLAPESQQLCAPEDLSTKQEQTLQDPGEGCRDQDAPEEQQEDRSEDHEGSDIDCEGKDIDCAIREERLSSRLLQSGGQGPSFSDYLYFKHRDEGLKELLERKMEKQAVLLGI", "length": 746 }, "evidence": [ { "id": "E1BCS0", "url": "https://omabrowser.org/oma/group/E1BCS0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N895-1", "protein_name": "Zinc finger protein 366", "gene_name": "ZNF366", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQKEMKMIKDEDVHFDLAVKKTPSFPHCLQPVASRGKAPQRHPFPEALRGPFSQFRYEPPPGDLDGFPGVFEGAGSRKRKSMPTKMPYNHPAEEVTLALHSEENKNHGLPNLPLLFPQPPRPKYDSQMIDLCNVGFQFYRSLEHFGGKPVKQEPIKPSAVWPQPTPTPFLPTPYPYYPKVHPGLMFPFFVPSSSPFPFSRHTFLPKQPPEPLLPRKAEPQESEETKQKVERVDVNVQIDDSYYVDVGGSQKRWQCPTCEKSYTSKYNLVTHILGHSGIKPHACTHCGKLFKQLSHLHTHMLTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSEVKPHNCRVCGRGFAYPSELKAHEAKHASGRENICVECGLDFPTLAQLKRHLTTHRGPIQYNCSECDKTFQYPSQLQNHMMKHKDIRPYICSECGMEFVQPHHLKQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCYKSFVQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHMHLHSDSKPFKCLYCPSKFTLKGNLTRHMKVKHGVMERGLHSQGLGRGRIALAQTAGVLRSLEQEEPFDLSQKRRAKVPVFQSDGESAQGSHCHEEEEEDNCYEVEPYSPGLAPQSQQLCTPEDLSTKSEHAPEVLEEACKEEKEDASKGEWEKRSKGDLGAEGGQERDCAGRDECLSLRAFQSTRRGPSFSDYLYFKHRDESLKELLERKMEKQAVLLGI", "length": 744 }, "evidence": [ { "id": "E1BCS0", "url": "https://omabrowser.org/oma/group/E1BCS0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ], "pmid": "" }, { "name": "response to estrogen", "id": "GO:0043627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043627", "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ], "pmid": "" }, { "name": "negative regulation of intracellular estrogen receptor signaling pathway", "id": "GO:0033147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033147", "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BCS0", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCS0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 742, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BCS0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BCS0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCS0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 255, "end_pos": 282, "start_aa": "Trp", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 396, "end_pos": 398 }, { "start_pos": 549, "end_pos": 551 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BCS1-1", "uniprot_ac": "E1BCS1", "uniprot_id": "E1BCS1_BOVIN", "mass": { "chemical_mass": 80814.0, "monoisotopic_mass": 80814.0 }, "refseq": { "ac": "XP_005219830", "name": "CCR4-NOT transcription complex subunit 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219830" }, "gene_names": [ { "name": "CNOT3", "type": "recommended", "evidence": [ { "id": "E1BCS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ] }, { "name": "CNOT3", "type": "synonym", "evidence": [ { "id": "XP_005219830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219830" } ] } ], "protein_names": [ { "name": "CCR4-NOT transcription complex subunit 3", "type": "recommended", "evidence": [ { "id": "E1BCS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCS1/entry#names_and_taxonomy" } ] }, { "name": "CCR4-NOT transcription complex subunit 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005219830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219830" } ] }, { "name": "CCR4-associated factor 3", "type": "synonym", "evidence": [ { "id": "E1BCS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCS1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity.", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1#function" }, { "database": "UniProtKB", "id": "PIRNR005290", "url": "https://www.uniprot.org/uniprotkb/PIRNR005290#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CNOT3", "url": "https://www.uniprot.org/uniprotkb/E1BCS1", "locus": { "chromosome": "18", "start_pos": 63240949, "end_pos": 63257101, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014900", "url": "https://www.ensembl.org/id/ENSBTAG00000014900" } ] } } ], "crossref": [ { "id": "E1BCS1", "url": "https://alphafold.ebi.ac.uk/entry/E1BCS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014900", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014900", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "527305", "url": "https://www.ncbi.nlm.nih.gov/gene/527305", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:527305", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527305", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NHYPHAP", "url": "https://omabrowser.org/oma/group/NHYPHAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCS1", "url": "https://www.orthodb.org/?gene=E1BCS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23326", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23326", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04065", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04065", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-429947", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-429947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6804115", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804115", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005219830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219830", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCS1-1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSSQHPQSPAVPPSYPPGPPPAASALSATPGSNGAPAAAAPASALGAKASPAPSHSAGTPAPYAQAVAPPAPSGPPSAQPRPPSAQPGAGSGGGGNSGGGGGAGKQNGATSYSSVVADSPAEAALSSTGGSSTGSQALGPPPGPHNPPPSTAKEPSATAPVGAGGVAPGSGNNAGGPSLLVPLPVNPPSSPTPSFNEAKAAGSLLNGPPQFSAAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDILLSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFEQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ", "length": 744, "header": "tr|E1BCS1-1|E1BCS1_BOVIN Isoform 1 of CCR4-NOT transcription complex subunit 3 OS=Bos taurus OX=9913 GN=CNOT3 PE=3 SV=3 CANONICAL=E1BCS1-1" }, "isoforms": [ { "isoform_ac": "E1BCS1-1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1/entry#E1BCS1-1", "sequence": { "sequence": "MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSSQHPQSPAVPPSYPPGPPPAASALSATPGSNGAPAAAAPASALGAKASPAPSHSAGTPAPYAQAVAPPAPSGPPSAQPRPPSAQPGAGSGGGGNSGGGGGAGKQNGATSYSSVVADSPAEAALSSTGGSSTGSQALGPPPGPHNPPPSTAKEPSATAPVGAGGVAPGSGNNAGGPSLLVPLPVNPPSSPTPSFNEAKAAGSLLNGPPQFSAAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDILLSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFEQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ", "length": 744, "header": "tr|E1BCS1-1|E1BCS1_BOVIN Isoform 1 of CCR4-NOT transcription complex subunit 3 OS=Bos taurus OX=9913 GN=CNOT3 PE=3 SV=3 CANONICAL=E1BCS1-1" }, "locus": { "chromosome": "18", "start_pos": 63252313, "end_pos": 63241953, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019836.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019836.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019836.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019836.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 337, "start_aa": "Thr", "end_pos": 337, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr337", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 500, "start_aa": "Thr", "end_pos": 500, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr500", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 636, "start_aa": "Thr", "end_pos": 636, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr636", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:527305", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527305", "resource": "KEGG Pathway" }, { "id": "R-BTA-429947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-429947", "resource": "Reactome", "description": "Deadenylation of mRNA" }, { "id": "R-BTA-6804115", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804115", "resource": "Reactome", "description": "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AE28-1", "protein_name": "CCR4-NOT transcription complex subunit 3", "gene_name": "CNOT3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPRTSEKQLGDGPGEGVVASVPGLRREAGFLLEWAVGHPEPHSGLDSLIPQLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPSYPSGPPPTASALSTTPGNNGAPAPAAPASALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTAQPRPPSVQPGGGGGGGSGGGGGGGSSNNSSGGGGAGKQNGATSYSSVVADSPAEVALSSSGGNTTSSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAASTLLNGPPQFSAAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFEQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ", "length": 774 }, "evidence": [ { "id": "E1BCS1", "url": "https://omabrowser.org/oma/group/E1BCS1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q55AA8-1", "protein_name": "NOT2/NOT3/NOT5 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNTRKLQGEIDKTLKKVADGIIEFDCVLKKVYSAISTNQKEKYESDLKKEIKKLQRYRDQIKAWIASNDVKNKAALLESRKSIEMILINFKKNKIKKMDSFRHLERGEGKGKYSKDGGVDSSTKDEMAKTHVKTWASKAIATLRAQLESFDTELENIPVRKRKTESARVEQLQKFKNNHKYHLLALEFLLRMMDDDRIPTDEIEKIKDSVECYIDSYTQEDTYEEPGEIYSIFNFKPHNITDIEDEDFDFSLDEESDDDDDDDDYSDASDHDDDDDESSSKKDSNSENEDEIKETPKVATATATATAEKSTQPIISTSIQQQLPQPNKSPILQPNNTARIGSPTPTTNLSQQTQPTKASTPSPTFSSVTKTSIKNDNKQSHSQPTPVTIPNQQFPSLGNVPMAQRLMQQQAQQQAAAAAQLAAQQAQTQQTQQQQQQQQQQQQQQQQQQQQQQQQQNQQQQAPPQQQQAPQQQQQQNTQFKNKTGQSDINDVQDSLSQLNIKQQQQPPQQPQQQQQQQQQQQQQQQQQQQQQPQADLDDSKNNETFDNSSNLYPGTLAEISTISRINDGTYQQQHQQQQQQQSHQQSHQQSHQQSQQQSQQSQHHHQQQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQQQQPQHQSQQHQPQPQQPQQPQQPQHQPYHQQQSYQQQQQQQQQQYQQQQQQQQQQYQQQQMSQNQNQNQSQQQQQSGQLGFEEAMILTRHMMDISFKNLPDFKDYERIPTFIPRNPKPVPQYYPQSTLPLFESPNVFEKFDIDTLFFIFYFKQGTYQQYQAAKELKKQGWRYHKKYLTWFRRHEEPKEITNEFEQGTYVYFDYETGWCQRKKTEFTFEYRFLEE", "length": 866 }, "evidence": [ { "id": "E1BCS1", "url": "https://omabrowser.org/oma/group/E1BCS1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8K0V4-1", "protein_name": "CCR4-NOT transcription complex subunit 3", "gene_name": "Cnot3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTDRDIILSSTSAPPTSSQPPLQLSEVNIPLSLGVCPLGPVSLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFEQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ", "length": 751 }, "evidence": [ { "id": "E1BCS1", "url": "https://omabrowser.org/oma/group/E1BCS1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "pmid": "" }, { "name": "CCR4-NOT core complex", "id": "GO:0030015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030015", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "pmid": "" }, { "name": "trophectodermal cell differentiation", "id": "GO:0001829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001829", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "pmid": "" }, { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "pmid": "" }, { "name": "regulation of stem cell population maintenance", "id": "GO:2000036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000036", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": "https://www.uniprot.org/uniprotkb/E1BCS1" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0000289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000289", "evidence": [ { "database": "UniProtKB", "id": "E1BCS1", "url": 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179163" } ] } ], "function": [ { "annotation": "Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.", "evidence": [ { "database": "UniProtKB", "id": "E1BCX2", "url": "https://www.uniprot.org/uniprotkb/E1BCX2#function" }, { "database": "UniProtKB", "id": "ARBA00059783", "url": "https://www.uniprot.org/uniprotkb/ARBA00059783#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BCX2", "url": "https://www.uniprot.org/uniprotkb/E1BCX2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ABRA", "url": "https://www.uniprot.org/uniprotkb/E1BCX2", "locus": { 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"https://www.ebi.ac.uk/interpro/entry/IPR038095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539379", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539379", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEPKWRS", "url": "https://omabrowser.org/oma/group/DEPKWRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BCX2", "url": "https://www.orthodb.org/?gene=E1BCX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22739", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22739", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22739:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22739:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179163", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179163", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BCX2", "url": "https://www.uniprot.org/uniprotkb/E1BCX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCX2-1", "url": "https://www.uniprot.org/uniprotkb/E1BCX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPGEKKRGDGPAKSALRKVHTATLVITLARGWQQWANENSIRQAQEPAGWMPGGTQDPADASGPAIDAPSRWKAQRAPKPSSPKPEGCGEDGRGSEEASAVSPIKRKEVTKTVVSKAYERGGDLGHLSHRYEQDGDQPETRQPESDVDRLLRSRGSPTLRRKCAKLVTELTRGWKAMEQEEPKCRSDSVDTEDSGYGGETDERPEPDGEQVAVARIRRPLPSQANRFTEKLNCKAQRKYSQVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGTKTAERAKRAEEHIYREILDMCFIIRSMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLVDFEGEMLWQGRDDHVVITLLK", "length": 382, "header": "tr|E1BCX2-1|E1BCX2_BOVIN Isoform 1 of Actin-binding Rho-activating protein OS=Bos taurus OX=9913 GN=ABRA PE=4 SV=1 CANONICAL=E1BCX2-1" }, "isoforms": [ { "isoform_ac": "E1BCX2-1", "url": "https://www.uniprot.org/uniprotkb/E1BCX2/entry#E1BCX2-1", "sequence": { "sequence": "MAPGEKKRGDGPAKSALRKVHTATLVITLARGWQQWANENSIRQAQEPAGWMPGGTQDPADASGPAIDAPSRWKAQRAPKPSSPKPEGCGEDGRGSEEASAVSPIKRKEVTKTVVSKAYERGGDLGHLSHRYEQDGDQPETRQPESDVDRLLRSRGSPTLRRKCAKLVTELTRGWKAMEQEEPKCRSDSVDTEDSGYGGETDERPEPDGEQVAVARIRRPLPSQANRFTEKLNCKAQRKYSQVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGTKTAERAKRAEEHIYREILDMCFIIRSMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLVDFEGEMLWQGRDDHVVITLLK", "length": 382, "header": "tr|E1BCX2-1|E1BCX2_BOVIN Isoform 1 of Actin-binding Rho-activating protein OS=Bos taurus OX=9913 GN=ABRA PE=4 SV=1 CANONICAL=E1BCX2-1" }, "locus": { "chromosome": "14", "start_pos": 57828619, "end_pos": 57818330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024417.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024417.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024417.5", "url": "https://www.ensembl.org/id/ENSBTAP00000024417.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539379", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539379", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZTQ0-1", "protein_name": "Actin-binding Rho-activating protein", "gene_name": "ABRA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARGEKGRGEGPAKSALRKVRTATLVINLARGWQQWANENSTRQAQEPTGWMPGGARESDQPSGPVIYPTTHQKVQSAPKSPSPKPGGYGAGQSSEGATEVSPIKRKEVTKTIVSKAYERGGDVSHLSHRYEKDGDEPEPEQPESDIDRLLRSHGSPTRRRKCANLVSELTKGWKEMEQEEQEELKCRSDSIDTEDSGYGGETEERPEQDGEQVAIARIKRPLPSQANRFTEKLNCKAQRKYSQVGHLKGRWQQWADEHIQSQKLNPFSDEFDYELAMSTRLHKGDEGYGRPKEGTRTAERAKRAEEHIYREIMDMCFIIRTMAHPRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLVDFEGEMLWQGRDDHVVITLLK", "length": 384 }, "evidence": [ { "id": "E1BCX2", "url": "https://omabrowser.org/oma/group/E1BCX2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BUZ1-1", "protein_name": "Actin-binding Rho-activating protein", "gene_name": "Abra", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPGEREREAGPAKSALRKVRTATLVINLARGWQQWANENSTKQAQEPAGWLPGATHDLPNAPKEAGPYQHAPKTLSPKPDRDGEGQHSEEATEVSHIKRKEVTRTVVSKAYERGGDVNYLSHRYENDGGVSEAIQPENDIDRILLSHDSPTRRRKCTNLVSELTKGWKVMEQEEPTWKSDSVDTEDSGYGGDMEERPEQDAAPVAPARIKRPLLSQANRYSETLNCKAHRKYSQVDNLKGRWQQWADEHVQSQKLNPFSDEFDYDLAMSTRLHKGDEGYGRPKEGSKTAERAKRAEEHIYREIMELCFVIRTMARHRRDGKIQVTFGELFDRYVRISDKVVGILMRARKHGLVHFEGEMLWQGRDDHVVITLLE", "length": 375 }, "evidence": [ { "id": "E1BCX2", "url": "https://omabrowser.org/oma/group/E1BCX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K4K7-1", "protein_name": "Actin-binding Rho-activating protein", "gene_name": "Abra", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPGETEREAGPAKSALQKVRRATLVINLARGWQQWANENSTRQAQEPAGWLPGATQDLPHTPKEPGPRQHAPKPPSPKPDGDREGRGSEEATEVSHIKRKEVTRTVVSKAYERGGDVNYLSHRYEHDGGVSEAVQPDNDIDRILLSHDSPTRRRKCTNLVSELTKGWKVMEQEEPKWKSDSIDTEDSGYGGDMEERPEQDVAQVAAARIKRPLHSQANRYSETLNCKAHRKYSQVDNLKGRWQQWADEHIQSQKLNPFSDEFDYDLAMSTRLHKGDEGYGRPKEGSKTAERAKRAEEHIYREIMELCFVIRTMARHRRDGKIQVTFGELFDRYVRISDKVVGILMRARKHGLVHFEGEMLWQGKDDHVVITLLE", "length": 375 }, "evidence": [ { "id": "E1BCX2", "url": "https://omabrowser.org/oma/group/E1BCX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N0Z2-1", "protein_name": "Actin-binding Rho-activating protein", "gene_name": "ABRA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPGEKESGEGPAKSALRKIRTATLVISLARGWQQWANENSIRQAQEPTGWLPGGTQDSPQAPKPITPPTSHQKAQSAPKSPPRLPEGHGDGQSSEKAPEVSHIKKKEVSKTVVSKTYERGGDVSHLSHRYERDAGVLEPGQPENDIDRILHSHGSPTRRRKCANLVSELTKGWRVMEQEEPTWRSDSVDTEDSGYGGEAEERPEQDGVQVAVVRIKRPLPSQVNRFTEKLNCKAQQKYSPVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGTKTAERAKRAEEHIYREMMDMCFIICTMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLVDFEGEMLWQGRDDHVVITLLK", "length": 381 }, "evidence": [ { "id": "E1BCX2", "url": "https://omabrowser.org/oma/group/E1BCX2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "E1BCX2", "url": "https://www.uniprot.org/uniprotkb/E1BCX2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "E1BCX2", "url": "https://www.uniprot.org/uniprotkb/E1BCX2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BCX2", "url": "https://www.uniprot.org/uniprotkb/E1BCX2" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "E1BCX2", "url": "https://www.uniprot.org/uniprotkb/E1BCX2" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "E1BCX2", "url": "https://www.uniprot.org/uniprotkb/E1BCX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BCZ7", "url": "https://www.uniprot.org/uniprotkb/E1BCZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "E1BCZ7", "url": "https://www.uniprot.org/uniprotkb/E1BCZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BCZ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 407, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BCZ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BCZ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BCZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 350, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BD03-1", "uniprot_ac": "E1BD03", "uniprot_id": "E1BD03_BOVIN", "mass": { "chemical_mass": 66268.0, "monoisotopic_mass": 66268.0 }, "refseq": { "ac": "NP_001178373", "name": "protein phosphatase 1D", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178373" }, "gene_names": [ { "name": "PPM1D", "type": "recommended", "evidence": [ { "id": "E1BD03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BD03" } ] }, { "name": "PPM1D", "type": "synonym", "evidence": [ { "id": "NP_001178373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178373" } ] } ], "protein_names": [ { "name": "Protein phosphatase, Mg2+/Mn2+ dependent 1D", "type": "synonym", "evidence": [ { "id": "E1BD03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BD03/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1D", "type": "synonym", "evidence": [ { "id": "NP_001178373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178373" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BD03", "url": "https://www.uniprot.org/uniprotkb/E1BD03" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PPM1D", "url": "https://www.uniprot.org/uniprotkb/E1BD03", "locus": { "chromosome": "19", "start_pos": 12299125, "end_pos": 12359979, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009427", "url": "https://www.ensembl.org/id/ENSBTAG00000009427" } ] } } ], "crossref": [ { "id": "E1BD03", "url": "https://alphafold.ebi.ac.uk/entry/E1BD03", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009427", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009427", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514005", "url": "https://www.ncbi.nlm.nih.gov/gene/514005", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514005", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514005", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTIMDQK", "url": "https://omabrowser.org/oma/group/NTIMDQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BD03", "url": "https://www.orthodb.org/?gene=E1BD03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47992", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47992", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8878166", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8878166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178373", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178373", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BD03", "url": "https://www.uniprot.org/uniprotkb/E1BD03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BD03-1", "url": "https://www.uniprot.org/uniprotkb/E1BD03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPAAEEELSSRRSPSRPPPPPRSPPPPAGGEVAGRGAAGAAREARAAPPDAGASPAPGRCCRRRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQRGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGLKMYVAHVGDSGVVLGIQDDPKDDFIRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPGVDSQGHFTSEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVKPLEEDPWPRLNSKDHIPALIRSNAFSENYLEVPPEIARGNVQAAVISSKDPEPLEENCTKALTLRIHDSLNNSLSVGLVPTNSTNTITDQKNVKISSPGQMKAQEVERTPPANFKRTLEESNSGPLMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTVRRRLRGQKKIGNPLLHQHRKTVCVC", "length": 605, "header": "tr|E1BD03-1|E1BD03_BOVIN Isoform 1 of Protein phosphatase, Mg2+/Mn2+ dependent 1D OS=Bos taurus OX=9913 GN=PPM1D PE=3 SV=2 CANONICAL=E1BD03-1" }, "isoforms": [ { "isoform_ac": "E1BD03-1", "url": "https://www.uniprot.org/uniprotkb/E1BD03/entry#E1BD03-1", "sequence": { "sequence": "MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPAAEEELSSRRSPSRPPPPPRSPPPPAGGEVAGRGAAGAAREARAAPPDAGASPAPGRCCRRRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQRGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGLKMYVAHVGDSGVVLGIQDDPKDDFIRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPGVDSQGHFTSEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVKPLEEDPWPRLNSKDHIPALIRSNAFSENYLEVPPEIARGNVQAAVISSKDPEPLEENCTKALTLRIHDSLNNSLSVGLVPTNSTNTITDQKNVKISSPGQMKAQEVERTPPANFKRTLEESNSGPLMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTVRRRLRGQKKIGNPLLHQHRKTVCVC", "length": 605, "header": "tr|E1BD03-1|E1BD03_BOVIN Isoform 1 of Protein phosphatase, Mg2+/Mn2+ dependent 1D OS=Bos taurus OX=9913 GN=PPM1D PE=3 SV=2 CANONICAL=E1BD03-1" }, "locus": { "chromosome": "19", "start_pos": 12359747, "end_pos": 12300047, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012404.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012404.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012404.5", "url": "https://www.ensembl.org/id/ENSBTAP00000012404.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514005", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514005", "resource": "KEGG Pathway" }, { "id": "R-BTA-8878166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8878166", "resource": "Reactome", "description": "Transcriptional regulation by RUNX2" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NXQ2-1", "protein_name": "Protein phosphatase, Mg2+/Mn2+ dependent 1D", "gene_name": "PPM1D", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEGPYSLGVSVYSDQGGRKYMEDVTQIVVEPEPPAAAERGPAHKGGAAPGDGVRRRAGGPRAAEEGALPPGPGCGSGRRPRRSVAFFAVCDGHGGREAAQFARENLWGFIKKQKGFGSAEPAAVCAALRKGFIACHRAMWKKLPEWPKTMTGLPSTSGTTASVVIIRGSKMYVAHVGDSGVVLGVQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVINKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFYSGEFVVSPEPDTSVHTIDPQKHKYIILGSDGLWNMIPPQDAISMCQDHEEKKYFMGEHRQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPLQDSKNNLENEEELYLNLADSPCYSSPDTNIMTPSRCCTPPVKLLEDDPWPRLNASEPVPSLMHSNVISEKYAELPNEIAKSNLPSSGATLKDSGPQDEKCSKALALRIQESYSNGLSVSLSPSNSTISGTDQKGLKVSPNGQTKAQDAERTPTANFKRTLEESNSGPAVKKPRRGLSRSMGVQAEGISTTPQRKNSNKLAMRRSLRGQKKLSSSLFHPPRKAVCVC", "length": 590 }, "evidence": [ { "id": "E1BD03", "url": "https://omabrowser.org/oma/group/E1BD03/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B1WCA0-1", "protein_name": "Protein phosphatase, Mg2+/Mn2+ dependent, 1D", "gene_name": "Ppm1d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPAAEDKPAPVPRRALGLPATPSLVGVGPSGKGPAAARDPAPDAAASLPAGRCCRRRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHSGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGKFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMVPPQDAISMCQDQEEKKYLMGEQGQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPEVDNQGNFTNEDELFLNLTDSPTYNSQETCVMTPSPSSTPPVKSLEEDPWPRLNSKDHIPALVRSNAFSEKFLEVPAEIARGSIQTVVMTSKDSETLEENCPKALTLRIHDSLNNTLSVGLMPTNSTNTIMDQKNLKMSTPGQMKAQEVERTPPANFKRTLEESNSGPLMKKHRRNGLSRNSGAQASSLPTASQRRHSVTLTMRRRLRGQKKMGNPLLHQHRKTVCVC", "length": 598 }, "evidence": [ { "id": "E1BD03", "url": "https://omabrowser.org/oma/group/E1BD03/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LH52-1", "protein_name": "Protein phosphatase, Mg2+/Mn2+ dependent 1D", "gene_name": "PPM1D", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTTEEKPSPRRSLSQPSPPQRTPPALPGGEVSGKGPAVAAREARDAPPDAGASPAPGRCCRRRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGLKMYVAHVGDSGVVLGIQDDPKDDFIRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAVSMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPGVDSKGNFANEDELYLNLTDSPSYNSQETCVITPSPCSTPPVKSLEEDPWPRLNSKDHISALVRSSAFSENYLEVPTEMARGNIQPAVISSKDPEPLEENCTKALTLRIHDSLNNSLSVGLVPTNSTNSVMDQKNLKMSTPGQMKAQEVERTPPANFKRTLEESNSGPLMKKHRRNGLSRNSGAQPASLPTTSQRKNSVKLTMRRRLRGQKKIGNPLLHQHRKTVCVC", "length": 605 }, "evidence": [ { "id": "E1BD03", "url": "https://omabrowser.org/oma/group/E1BD03/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15297-1", "protein_name": "Protein phosphatase 1D", "gene_name": "PPM1D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPGGEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPEVDNQGNFTNEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVKSLEEDPWPRVNSKDHIPALVRSNAFSENFLEVSAEIARENVQGVVIPSKDPEPLEENCAKALTLRIHDSLNNSLPIGLVPTNSTNTVMDQKNLKMSTPGQMKAQEIERTPPTNFKRTLEESNSGPLMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTMRRRLRGQKKIGNPLLHQHRKTVCVC", "length": 605 }, "evidence": [ { "id": "E1BD03", "url": "https://omabrowser.org/oma/group/E1BD03/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZ67-1", "protein_name": "Protein phosphatase 1D", "gene_name": "Ppm1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF06524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BD90", "url": "https://www.uniprot.org/uniprotkb/E1BD90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BD90-1", "url": "https://www.uniprot.org/uniprotkb/E1BD90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKKKTGARKKAENHQEREKQLRASRSTIDLAKHPCNTLECDKCQRRQKNKAFCYFCNSVQKLPICAQCGKTKCMMKSLDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTNAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLCCKACFCDDHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMSTRSLKFGMQTGGEEGDGASGYDAYWKNLASDKHAGATYHDEEEDEYETEDDEEEEDEGGKDSDADSSDLFTNLNLGKTYASGCAHYEEQEN", "length": 319, "header": "tr|E1BD90-1|E1BD90_BOVIN Isoform 1 of Zinc finger protein 330 OS=Bos taurus OX=9913 GN=LOC787714 PE=3 SV=2 CANONICAL=E1BD90-1" }, "isoforms": [ { "isoform_ac": "E1BD90-1", "url": "https://www.uniprot.org/uniprotkb/E1BD90/entry#E1BD90-1", 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"https://www.ncbi.nlm.nih.gov/protein/XP_015316581" }, "gene_names": [ { "name": "DRGX", "type": "recommended", "evidence": [ { "id": "E1BDA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDA0" } ] }, { "name": "DRGX", "type": "synonym", "evidence": [ { "id": "XP_015316581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316581" } ] } ], "protein_names": [ { "name": "Dorsal root ganglia homeobox protein", "type": "recommended", "evidence": [ { "id": "E1BDA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDA0/entry#names_and_taxonomy" } ] }, { "name": "Paired-related homeobox protein-like 1", "type": "synonym", "evidence": [ { "id": "E1BDA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDA0/entry#names_and_taxonomy" } ] }, { "name": "dorsal root ganglia homeobox protein", "type": "synonym", "evidence": [ { "id": "XP_015316581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316581" } ] } ], "function": [ { "annotation": "Transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perception of pain.", "evidence": [ { "database": "UniProtKB", "id": "E1BDA0", "url": "https://www.uniprot.org/uniprotkb/E1BDA0#function" }, { "database": "UniProtKB", "id": "ARBA00058719", "url": "https://www.uniprot.org/uniprotkb/ARBA00058719#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDA0", "url": "https://www.uniprot.org/uniprotkb/E1BDA0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DRGX", "url": "https://www.uniprot.org/uniprotkb/E1BDA0", "locus": { "chromosome": "28", "start_pos": 43578135, "end_pos": 43613106, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011991", "url": "https://www.ensembl.org/id/ENSBTAG00000011991" } ] } } ], "crossref": [ { "id": "E1BDA0", "url": "https://alphafold.ebi.ac.uk/entry/E1BDA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011991", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011991", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "521995", "url": "https://www.ncbi.nlm.nih.gov/gene/521995", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521995", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521995", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NHAPTDF", "url": "https://omabrowser.org/oma/group/NHAPTDF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BDA0", "url": "https://www.orthodb.org/?gene=E1BDA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24329:SF542", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24329:SF542", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015316581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316581", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BDA0", "url": "https://www.uniprot.org/uniprotkb/E1BDA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDA0-1", "url": "https://www.uniprot.org/uniprotkb/E1BDA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFYFHCPPQLEGTAPFGNHSTGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNLNSPPPGDQARSKKEALEAQQSLGRTVGPTGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQTNRTASVAALRMKAREHSEAVLQSANLLPSTSSSPSPVAKPAPLDGSQDKTPPSKEQSEHEKSV", "length": 263, "header": "tr|E1BDA0-1|E1BDA0_BOVIN Isoform 1 of Dorsal root ganglia homeobox protein OS=Bos taurus OX=9913 GN=DRGX PE=4 SV=2 CANONICAL=E1BDA0-1" }, "isoforms": [ { "isoform_ac": "E1BDA0-1", "url": "https://www.uniprot.org/uniprotkb/E1BDA0/entry#E1BDA0-1", "sequence": { "sequence": "MFYFHCPPQLEGTAPFGNHSTGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNLNSPPPGDQARSKKEALEAQQSLGRTVGPTGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQTNRTASVAALRMKAREHSEAVLQSANLLPSTSSSPSPVAKPAPLDGSQDKTPPSKEQSEHEKSV", "length": 263, "header": "tr|E1BDA0-1|E1BDA0_BOVIN Isoform 1 of Dorsal root ganglia homeobox protein OS=Bos taurus OX=9913 GN=DRGX PE=4 SV=2 CANONICAL=E1BDA0-1" }, "locus": { "chromosome": "28", "start_pos": 43610753, "end_pos": 43579139, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015907.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015907.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015907.4", "url": "https://www.ensembl.org/id/ENSBTAP00000015907.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 146, "start_aa": "Thr", "end_pos": 146, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr146", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:521995", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521995", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MZ61-1", "protein_name": "Dorsal root ganglia homeobox protein", "gene_name": "Drgx", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFYFHCPPQLEGTAPFGNHSTGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGDQARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPSTSSSPSPASKQAPPEGSQDKTSPTKEQSEGEKSV", "length": 263 }, "evidence": [ { "id": "E1BDA0", "url": "https://omabrowser.org/oma/group/E1BDA0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1X1M6-1", "protein_name": "Dorsal root ganglia homeobox protein", "gene_name": "DRGX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFYFHCPPQLEGTAPFGNHSTGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASEQEPGAKEPMAEVTPPPVRNINSPPPGDQARSKKEALEAQQSLGRTVGPTGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPSTSSSPSPAAKPAPPDSSQDKTPLGKEQNEGEKSV", "length": 263 }, "evidence": [ { "id": "E1BDA0", "url": "https://omabrowser.org/oma/group/E1BDA0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZDA2-1", "protein_name": "Dorsal root ganglia homeobox protein", "gene_name": "DRGX", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFYFHCPPQLEGAAPFGAHSAGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGSSDQEGSKEAMAEVAPPVRNLNSPSPADQTRNKKESLEIQQSLSRAVGPTGPFFPSCLPGTLLNTATYAQALSHVASLKGSPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPTTGSPTPPAKPSPDSSQDKQLSPAKEHMEGEKSV", "length": 260 }, "evidence": [ { "id": "E1BDA0", "url": 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"length": 1063, "header": "tr|E1BDB1-1|E1BDB1_BOVIN Isoform 1 of Ras-interacting protein 1 OS=Bos taurus OX=9913 GN=RASIP1 PE=4 SV=2 CANONICAL=E1BDB1-1" }, "locus": { "chromosome": "18", "start_pos": 55372934, "end_pos": 55359326, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015431.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015431.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015431.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015431.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1061, "start_aa": "Thr", "end_pos": 1061, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1061", "evidence": [ { "id": "", "database": "GlyGen", 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"https://www.uniprot.org/uniprotkb/E1BDB1" } ], "pmid": "" }, { "name": "negative regulation of membrane permeability", "id": "GO:1905709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905709", "evidence": [ { "database": "UniProtKB", "id": "E1BDB1", "url": "https://www.uniprot.org/uniprotkb/E1BDB1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "E1BDB1", "url": "https://www.uniprot.org/uniprotkb/E1BDB1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1BDB1", "url": "https://www.uniprot.org/uniprotkb/E1BDB1" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": 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with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377504" }, "gene_names": [ { "name": "OR4D11B", "type": "recommended", "evidence": [ { "id": "E1BDB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDB3" } ] }, { "name": "OR4D11B", "type": "synonym", "evidence": [ { "id": "NP_001377504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377504" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BDB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDB3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4D11", "type": "synonym", "evidence": [ { "id": "NP_001377504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377504" } ] }, { "name": "olfactory receptor family 4 subfamily D member 11B", "type": "synonym", "evidence": [ { "id": "NP_001377504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377504" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377504", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377504" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BDB3", "url": "https://www.uniprot.org/uniprotkb/E1BDB3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDB3", "url": "https://www.uniprot.org/uniprotkb/E1BDB3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4D11B", "url": "https://www.uniprot.org/uniprotkb/E1BDB3", "locus": { "chromosome": "15", "start_pos": 82703629, "end_pos": 82702694, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000069339", "url": "https://www.ensembl.org/id/ENSBTAG00000069339" } ] } } ], "crossref": [ { "id": "E1BDB3", "url": "https://alphafold.ebi.ac.uk/entry/E1BDB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "788587", "url": "https://www.ncbi.nlm.nih.gov/gene/788587", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:788587", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788587", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MENCTRV", "url": "https://omabrowser.org/oma/group/MENCTRV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BDB3", "url": "https://www.orthodb.org/?gene=E1BDB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377504", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377504", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BDB3", "url": "https://www.uniprot.org/uniprotkb/E1BDB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDB3-1", "url": "https://www.uniprot.org/uniprotkb/E1BDB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELGNGTRVKEFIFLGLTQNQELSLVLFLFLLLVYVTTLLGNLLIMVTVTRDSRLHTPMYFLLRNLSVADICFSSITAPKVLADLLVQRKAISFNGCFTQMFFFHLIGGVDVASLSLMAFDRYVAITKPLHYVTIMSRGRCTALIMASWAGGFVHSIVQISLLLPLPFCGPNVLDTFYCDVPQVLTLACTDIFILELLMISNSGLLTTLWFVFLLVSYMVILLLIRSQAGEGRGKAISTCTAHITVVTLHFVPCIYVYARPFSTLPTDKAVSVTFTVISPLLNPLIYTLRNQEMKAAMRRLRGRLGPSDKE", "length": 311, "header": "tr|E1BDB3-1|E1BDB3_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4D11B PE=3 SV=3 CANONICAL=E1BDB3-1" }, "isoforms": [ { "isoform_ac": "E1BDB3-1", "url": "https://www.uniprot.org/uniprotkb/E1BDB3/entry#E1BDB3-1", "sequence": { "sequence": 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"EMENYTRVKELIFLGLTQSHEVSMVLFLFLLLVYVTTLLGNLLIMVTVTYESRLHTPMYFLLRNLSIADICFSSITAPKVLVDLLSDRKTISFNGCLTQMFFFHLIGGVDVFSLSVMALDRYVAISKPLHYVTIMSRGRCIGLIAASWVGGFAHSIVQISLLLTLPFCGPNVLDTFYCDVPQVIKLACTDIFVLELLMISNNGMLTTLWFFLLLISYMVILLLLRSHSGEGRKKAISTCTSHITVITLHFVPCIYVYARPFTALPTDKAISVTFTVISPLLNPLIYTLRNQEMKSAMRRLRKRLGPSHRIEK", "length": 312 }, "evidence": [ { "id": "E1BDB3", "url": "https://omabrowser.org/oma/group/E1BDB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "K7N659-1", "protein_name": "Olfactory receptor", "gene_name": "Or4d10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EMENYTRVKELIFLGLTQSQEVSMVLFLFLLLVYVTTLLGNLLIMVTVTCESRLHTPMYFLLRNLSVADICFSSITAPKVLVDLLSDRKTISFNGCLTQMFFFHLIGGVDVFSLSVMALDRYVAISKPLHYVTIMSRGRCIGLIVASWVGGFAHSIVQISLLLTLPFCGPNVLDTFYCDVPQVIKLACTDIFVLELLMISNNGMLTTLWFFLLLVSYMVILLLLKSQSGEGKKKAISTCTSHITVITLHFVPCIYVYARPFTALPTDKAISVTFTVISPLLNPLIYTLRNQEMKSAMRRLRKRLGPSYWIER", "length": 312 }, "evidence": 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"E1BDC1", "url": "https://www.uniprot.org/uniprotkb/E1BDC1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BDC1", "url": "https://www.uniprot.org/uniprotkb/E1BDC1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "E1BDC1", "url": "https://www.uniprot.org/uniprotkb/E1BDC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDC1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 575, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDC1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDC1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDC1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 294, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDC8-1", "uniprot_ac": "E1BDC8", "uniprot_id": "E1BDC8_BOVIN", "mass": { "chemical_mass": 17263.0, "monoisotopic_mass": 17263.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Glycine cleavage system H protein", "type": "recommended", "evidence": [ { "id": "E1BDC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDC8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "The H protein shuttles the methylamine group of glycine from the P protein to the T protein.", "evidence": [ { "database": "UniProtKB", "id": "E1BDC8", "url": "https://www.uniprot.org/uniprotkb/E1BDC8#function" }, { "database": "UniProtKB", "id": "RU364055", "url": "https://www.uniprot.org/uniprotkb/RU364055#function" } ] }, { "annotation": "The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). Has a pivotal role in the lipoylation of enzymes involved in cellular energetics such as the mitochondrial dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (DLAT), and the mitochondrial dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (DLST).", "evidence": [ { "database": "UniProtKB", "id": "E1BDC8", "url": "https://www.uniprot.org/uniprotkb/E1BDC8#function" }, { "database": "UniProtKB", "id": "ARBA00046240", "url": "https://www.uniprot.org/uniprotkb/ARBA00046240#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDC8", "url": "https://www.uniprot.org/uniprotkb/E1BDC8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BDC8", "locus": {} } ], "crossref": [ { "id": "E1BDC8", "url": "https://alphafold.ebi.ac.uk/entry/E1BDC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046345", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046345", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06848", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06848", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HEWAKHE", "url": "https://omabrowser.org/oma/group/HEWAKHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11715", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11715", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11715:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11715:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BDC8", "url": "https://www.uniprot.org/uniprotkb/E1BDC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDC8-1", "url": "https://www.uniprot.org/uniprotkb/E1BDC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AACAHLAPGAPCSPRPWGLRVGAVWALRTGPARLSVRKFTEKHEWVTTENGVGTVGISNFAQEALGDVVYCSLPEVGTKLNKQEEFGALESVKAASELYSPVSGEAAEINKALAENPGLVNKSCYEDGWLIKMTFSNPSELDELTREEAYEKYIKSTEE", "length": 159, "header": "tr|E1BDC8-1|E1BDC8_BOVIN Isoform 1 of Glycine cleavage system H protein OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=E1BDC8-1" }, "isoforms": [ { "isoform_ac": "E1BDC8-1", "url": "https://www.uniprot.org/uniprotkb/E1BDC8/entry#E1BDC8-1", "sequence": { "sequence": "AACAHLAPGAPCSPRPWGLRVGAVWALRTGPARLSVRKFTEKHEWVTTENGVGTVGISNFAQEALGDVVYCSLPEVGTKLNKQEEFGALESVKAASELYSPVSGEAAEINKALAENPGLVNKSCYEDGWLIKMTFSNPSELDELTREEAYEKYIKSTEE", "length": 159, "header": "tr|E1BDC8-1|E1BDC8_BOVIN Isoform 1 of Glycine cleavage system H protein OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=E1BDC8-1" }, "locus": { "chromosome": "16", "start_pos": 77634272, "end_pos": 77633796, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011039.5", "url": "https://www.ensembl.org/id/ENSBTAT00000011039.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011039.4", "url": "https://www.ensembl.org/id/ENSBTAP00000011039.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q9LQL0-1", "protein_name": "Glycine cleavage system H protein 3, mitochondrial", "gene_name": "GDH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MALRMWASSTANALKLSSSASKSHLLPAFSISRCFSSVLEGLKYANSHEWVKHEGSVATIGITDHAQDHLGEVVFVELPEANSSVSKEKSFGAVESVKATSEILSPISGEVIEVNTKLTESPGLINSSPYEDGWMIKVKPSSPAELEALMGPKEYTKFCEEEDAAH", "length": 166 }, "evidence": [ { "id": "E1BDC8", "url": "https://omabrowser.org/oma/group/E1BDC8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": 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"annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDC8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 159, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDC8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDC8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDC8" }, { "id": "PS50968", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50968" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipoyl-binding", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 134, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00583", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-209931", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-209931", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "20497", "url": "https://www.rhea-db.org/rhea/20497", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BDD3", "url": "https://www.uniprot.org/uniprotkb/E1BDD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDD3-1", "url": "https://www.uniprot.org/uniprotkb/E1BDD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1A1", "url": "https://www.uniprot.org/uniprotkb/F1N1A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1A1-1", "url": "https://www.uniprot.org/uniprotkb/F1N1A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPLKGSNWGEEARGVEGPSLSHRPFLKLGTPWVAAAPRMSTPSIHCLKPSPLHLPSGIPGSPGRQRRHTLPANEFRCLTPEDAAGVFEIEREAFISVSGNCPLNLDEVRHFLTLCPELSLGWFVEGRLVAFIIGSLWDEERLTQESLTLHRPGGRTAHLHALAVHHSFRQQGKGSVLLWRYLQHAGGQPAVRRAVLMCEDALVPFYQRFGFHPAGPCAVVVGSLTFTEMHCSLRGHAALRRNSDR", "length": 246, "header": "tr|E1BDD3-1|E1BDD3_BOVIN Isoform 1 of Serotonin N-acetyltransferase OS=Bos taurus OX=9913 GN=AANAT PE=3 SV=3 CANONICAL=E1BDD3-1" }, "isoforms": [ { "isoform_ac": "E1BDD3-1", "url": "https://www.uniprot.org/uniprotkb/E1BDD3/entry#E1BDD3-1", "sequence": { "sequence": "MGPLKGSNWGEEARGVEGPSLSHRPFLKLGTPWVAAAPRMSTPSIHCLKPSPLHLPSGIPGSPGRQRRHTLPANEFRCLTPEDAAGVFEIEREAFISVSGNCPLNLDEVRHFLTLCPELSLGWFVEGRLVAFIIGSLWDEERLTQESLTLHRPGGRTAHLHALAVHHSFRQQGKGSVLLWRYLQHAGGQPAVRRAVLMCEDALVPFYQRFGFHPAGPCAVVVGSLTFTEMHCSLRGHAALRRNSDR", "length": 246, "header": "tr|E1BDD3-1|E1BDD3_BOVIN Isoform 1 of Serotonin N-acetyltransferase OS=Bos taurus OX=9913 GN=AANAT PE=3 SV=3 CANONICAL=E1BDD3-1" }, "locus": { "chromosome": "19", "start_pos": 55290973, "end_pos": 55288604, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034708.5", "url": "https://www.ensembl.org/id/ENSBTAT00000034708.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034594.5", "url": "https://www.ensembl.org/id/ENSBTAP00000034594.5" } ] } }, { "isoform_ac": "F1N1A1-1", "url": "https://www.uniprot.org/uniprotkb/E1BDD3/entry#F1N1A1-1", "sequence": { "sequence": "MSTPSIHCLKPSPLHLPSGIPGSPGRQRRHTLPANEFRCLTPEDAAGVFEIEREAFISVSGNCPLNLDEVRHFLTLCPELSLGWFVEGRLVAFIIGSLWDEERLTQESLTLHRPGGRTAHLHALAVHHSFRQQGKGSVLLWRYLQHAGGQPAVRRAVLMCEDALVPFYQRFGFHPAGPCAVVVGSLTFTEMHCSLRGHAALRRNSDR", "length": 207, "header": "tr|F1N1A1-1|E1BDD3_BOVIN Computationally mapped isoform of Serotonin N-acetyltransferase OS=Bos taurus OX=9913 GN=AANAT PE=3 SV=1 CANONICAL=E1BDD3-1" }, "locus": { "chromosome": "19", "start_pos": 55289837, "end_pos": 55288604, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019543.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019543.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019543.5", "url": "https://www.ensembl.org/id/ENSBTAP00000019543.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-209931", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-209931", "resource": "Reactome", "description": "Serotonin and melatonin biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ATZ0-1", "protein_name": "Serotonin N-acetyltransferase", "gene_name": "AANAT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAQTSHYLKPRPLSLPPTIPESPSRQRRHTLPASEFRCLTPEDAAGVFELEREAFIPVSGTCPLNVDEVRHFLTLCPELSMGWFLEGRLLAFIIGSLWDKERITQESLTLHRPGGRTAHLHLLAVHRAFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCEARLVPFYQRFGFRPVGPCAVSVGSLVFTEMQCSMRDLVSQRRNSDC", "length": 207 }, "evidence": [ { "id": "E1BDD3", "url": "https://omabrowser.org/oma/group/E1BDD3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O88816-1", "protein_name": "Serotonin N-acetyltransferase", "gene_name": "Aanat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNINSLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESLTLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCEDALVPFYEKFGFQAVGPCAITVGSLTFTELQCSLRCHAFLRRNSGC", "length": 205 }, "evidence": [ { "id": "E1BDD3", "url": "https://omabrowser.org/oma/group/E1BDD3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P79774-1", "protein_name": "Serotonin N-acetyltransferase", "gene_name": "AANAT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPVLGAVPFLKPTPLQGPRNSPGRQRRHTLPASEFRCLSPEDAVSVFEIEREAFISVSGDCPLHLDEIRHFLTLCPELSLGWFEEGRLVAFIIGSLWDQDRLSQAALTLHNPRGTAVHIHVLAVHRTFRQQGKGSILMWRYLQYLRCLPCARRAVLMCEDFLVPFYEKCGFVAVGPCQVTVGTLAFTEMQHEVRGHAFMRRNSGC", "length": 205 }, "evidence": [ { "id": "E1BDD3", "url": "https://omabrowser.org/oma/group/E1BDD3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q16613-1", "protein_name": "Serotonin N-acetyltransferase", "gene_name": "AANAT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTQSTHPLKPEAPRLPPGIPESPSCQRRHTLPASEFRCLTPEDAVSAFEIEREAFISVLGVCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLMQESLTLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQPAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFMELHCSLRGHPFLRRNSGC", "length": 207 }, "evidence": [ { "id": "E1BDD3", "url": "https://omabrowser.org/oma/group/E1BDD3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64666-1", "protein_name": "Serotonin N-acetyltransferase", "gene_name": "Aanat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSIHPLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCPLHLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESLTLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCENALVPFYEKFGFQAMGPCAITMGSLTFTELQCSLRCHTFLRRNSGC", "length": 205 }, "evidence": [ { "id": "E1BDD3", "url": "https://omabrowser.org/oma/group/E1BDD3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BDD3", "url": "https://www.uniprot.org/uniprotkb/E1BDD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "E1BDD3", "url": "https://www.uniprot.org/uniprotkb/E1BDD3" } ], "pmid": "" }, { "name": "response to light stimulus", "id": "GO:0009416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009416", "evidence": [ { "database": "UniProtKB", "id": "E1BDD3", "url": "https://www.uniprot.org/uniprotkb/E1BDD3" } ], "pmid": "" }, { "name": "melatonin biosynthetic process", "id": "GO:0030187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030187", "evidence": [ { "database": "UniProtKB", "id": "E1BDD3", "url": "https://www.uniprot.org/uniprotkb/E1BDD3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aralkylamine N-acetyltransferase activity", "id": "GO:0004059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004059", "evidence": [ { "database": "UniProtKB", "id": "E1BDD3", "url": "https://www.uniprot.org/uniprotkb/E1BDD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20497", "name": "", "equation": "a 2-arylethylamine + acetyl-CoA = an N-acetyl-2-arylethylamine + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BDD3-1", "O02785-1", "A0AAA9TYB2-1" ], "evidence": [ { "id": "20497", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20497" } ] }, { "id": "R-BTA-209792", "name": "N-acetylation of serotonin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-209914" ], "output_participant_list": [], "enzyme_list": [ "E1BDD3-1" ], "evidence": [ { "id": "R-BTA-209792", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-209792" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-209914", "participant_name": "5HT [cytosol]", "crossref": [ { "id": "350546", "database": "ChEBI", "url": "" }, { "id": "ZINC000000057058", "database": "ZINC", "url": "" }, { "id": "C00780", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9TYB2", "gene_name": "LOC112442710", "activity": [ { "ec_number": "2.3.1.87", "activity": "serotonin + acetyl-CoA = N-acetylserotonin + CoA + H(+).", "evidence": [ { "id": "A0AAA9TYB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYB2" } ] }, { "ec_number": "2.3.1.87", "activity": "", "evidence": [ { "id": "A0AAA9TYB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYB2" } ] } ] }, { "uniprot_ac": "E1BDD3", "gene_name": "AANAT", "activity": [ { "ec_number": "2.3.1.87", "activity": "serotonin + acetyl-CoA = N-acetylserotonin + CoA + H(+).", "evidence": [ { "id": "E1BDD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDD3" } ] }, { "ec_number": "2.3.1.87", "activity": "", "evidence": [ { "id": "E1BDD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDD3" } ] } ] }, { "uniprot_ac": "O02785", "gene_name": "AANAT", "activity": [ { "ec_number": "2.3.1.87", "activity": "serotonin + acetyl-CoA = N-acetylserotonin + CoA + H(+).", "evidence": [ { "id": "O02785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02785" } ] }, { "ec_number": "2.3.1.87", "activity": "", "evidence": [ { "id": "O02785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02785" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDD3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 246, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDD3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDD3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDD3" }, { "id": "PS51186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 235, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.87", "ec_name": "serotonin + acetyl-CoA = N-acetylserotonin + CoA + H(+).", "evidence": [ { "id": "2.3.1.87", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.87" }, { "id": "2.3.1.87", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.87" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDE8-1", "uniprot_ac": "E1BDE8", "uniprot_id": "E1BDE8_BOVIN", "mass": { "chemical_mass": 56281.0, "monoisotopic_mass": 56281.0 }, "refseq": { "ac": "NP_001179282", "name": "recombining binding protein suppressor of hairless-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179282" }, "gene_names": [ { "name": "RBPJL", "type": "recommended", "evidence": [ { "id": "E1BDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDE8" } ] }, { "name": "RBPJL", "type": "synonym", "evidence": [ { "id": "NP_001179282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179282" } ] } ], "protein_names": [ { "name": "Recombining binding protein suppressor of hairless-like protein", "type": "recommended", "evidence": [ { "id": "E1BDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDE8/entry#names_and_taxonomy" } ] }, { "name": "Transcription factor RBP-L", "type": "synonym", "evidence": [ { "id": "E1BDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDE8/entry#names_and_taxonomy" } ] }, { "name": "recombining binding protein suppressor of hairless-like protein", "type": "synonym", "evidence": [ { "id": "NP_001179282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179282" } ] } ], "function": [ { "annotation": "Putative transcription factor, which cooperates with EBNA2 to activate transcription.", "evidence": [ { "database": "UniProtKB", "id": "E1BDE8", "url": "https://www.uniprot.org/uniprotkb/E1BDE8#function" }, { "database": "UniProtKB", "id": "ARBA00055625", "url": "https://www.uniprot.org/uniprotkb/ARBA00055625#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDE8", "url": "https://www.uniprot.org/uniprotkb/E1BDE8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RBPJL", "url": "https://www.uniprot.org/uniprotkb/E1BDE8", "locus": { "chromosome": "13", "start_pos": 73660385, "end_pos": 73649289, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011283", "url": "https://www.ensembl.org/id/ENSBTAG00000011283" } ] } } ], "crossref": [ { "id": "E1BDE8", "url": "https://alphafold.ebi.ac.uk/entry/E1BDE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011283", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011283", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540059", "url": "https://www.ncbi.nlm.nih.gov/gene/540059", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540059", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540059", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQGEHFH", "url": "https://omabrowser.org/oma/group/VQGEHFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BDE8", "url": "https://www.orthodb.org/?gene=E1BDE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10665", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10665", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179282", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179282", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BDE8", "url": "https://www.uniprot.org/uniprotkb/E1BDE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDE8-1", "url": "https://www.uniprot.org/uniprotkb/E1BDE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPVGADPSAPPGPLTHLSLPDSSEARPQSGADGRSLPGSWTRSSSEPSAVLREGVRRCLQQQCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPVPGQAHQAGQTGPLVCGYMGLDGASGSAAETQKLNFEEQPDSREFSCAKTLYISDADKRKHFRLVLRLMLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGDFVASARQWAAFTLHLADEQCSQGDFPPREGYVRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGGPPGGGGTYLCLATEKVVQFQASPCPNEANRALLNDNSCWTIIGTESVEFSFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAVFGSDWRWLRTPITVPVSLVRTDGLFYPSAFSFTYTPEYSARPGAPGALAAPAADADALLESIHHEFTRTNFHLFIQT", "length": 517, "header": "tr|E1BDE8-1|E1BDE8_BOVIN Isoform 1 of Recombining binding protein suppressor of hairless-like protein OS=Bos taurus OX=9913 GN=RBPJL PE=3 SV=2 CANONICAL=E1BDE8-1" }, "isoforms": [ { "isoform_ac": "E1BDE8-1", "url": "https://www.uniprot.org/uniprotkb/E1BDE8/entry#E1BDE8-1", "sequence": { "sequence": "MDPVGADPSAPPGPLTHLSLPDSSEARPQSGADGRSLPGSWTRSSSEPSAVLREGVRRCLQQQCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPVPGQAHQAGQTGPLVCGYMGLDGASGSAAETQKLNFEEQPDSREFSCAKTLYISDADKRKHFRLVLRLMLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGDFVASARQWAAFTLHLADEQCSQGDFPPREGYVRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGGPPGGGGTYLCLATEKVVQFQASPCPNEANRALLNDNSCWTIIGTESVEFSFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAVFGSDWRWLRTPITVPVSLVRTDGLFYPSAFSFTYTPEYSARPGAPGALAAPAADADALLESIHHEFTRTNFHLFIQT", "length": 517, "header": "tr|E1BDE8-1|E1BDE8_BOVIN Isoform 1 of Recombining binding protein suppressor of hairless-like protein OS=Bos taurus OX=9913 GN=RBPJL PE=3 SV=2 CANONICAL=E1BDE8-1" }, "locus": { "chromosome": "13", "start_pos": 73659381, "end_pos": 73649289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014992.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014992.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014992.5", "url": "https://www.ensembl.org/id/ENSBTAP00000014992.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540059", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540059", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BMW1-1", "protein_name": "Recombining binding protein suppressor of hairless-like protein", "gene_name": "RBPJL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPVGADPSGPPGPLTHLSLPDSSEARPQSGADGRSLRGSWTRSSPEPAALLREGVRWCLQQQCEQTVRILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPLQGQAHQAGETGPMVCGYMGLDGASGSAAETQKLNFEEQPDSREFGCAKTLYISDADKRKNFRLVLRLVLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGDFVASARQWAAFTLHLADEHSSQGDFPPREGYIRYGSLVQLVCTVSGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGGPPGGGGTYLCLATEKVVQFQASPCPKEANKALLNDSSCWTIIGTESVEFSFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMFRSPRSLVCVVPDVAAFGSDWRWLRTPITVPLSLVRADGLFYPSAFSFTYTPEYSARPGPPGAPAPAADPDELLESIHHEFTRTNFHLFIQT", "length": 516 }, "evidence": [ { "id": "E1BDE8", "url": "https://omabrowser.org/oma/group/E1BDE8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZSD9-1", "protein_name": "Recombining binding protein suppressor of hairless-like protein", "gene_name": "RBPJL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDPQRQAGADAAEPLTHPYRPRSRSPPRCWLRSNPYQADLLRDGVRRYLQLPAEQTVLILHAKVAQKSYGNEKRFFCPPPCVYLGGPGWKLKQEQLTARDVGEAGLRVWGYMGLDTMGSSLMETQKLSFEEQPDAKGFGCAKALYISDADKCKHFRLVLKLFFSNGQEIGTFHSKLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEGGAFIASARQWAAFTLHLADERCTRSEFPLREGYIRYGSVVQLICTATGITLPPLIIRKVSKQYAMLDVDEPISQLHKCAFQFQGSDHMYLCLSTEKVIQFQASPCPKEANRELLNDGSCWTIIGTETVEYSFSESLACAREPVSPVPLITALQLSGGGDVAMLEVQGEHFHAHLKVWFGDVEAETMYRSPKSLMCVVPDVSAFSSDWRWLRYPITVPLLLVRDDGLIYSSSFTFTYTPEQSFLPGQQLPADVPQDSDALLNSIHQEFTRTNFHLFMQS", "length": 501 }, "evidence": [ { "id": "E1BDE8", "url": "https://omabrowser.org/oma/group/E1BDE8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4AEG0-1", "protein_name": "Recombining binding protein suppressor of hairless-like protein", "gene_name": "Rbpjl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPGETTDPSVPPGPLTHLSLPDSSEVRLQNDGPSLLGSWTRSPPEHATILREGVRTCLQQRCEQTVWILHAKVAQKSYGTEKRFFCPPPCVYLAGPGWRVKPMQDQVHQSADTGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLFISDADKRKHFRLVLRLVQRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGDTPGGAGTYLCLSTEKVVRFQASLCPKEANRALLNDSSCWTIIGTESVEFSFSTSLACTPEPVTPVPHISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSAFSFTYTPEYSTRPRPPNAQEPAPDADALLESIHHEFTRTNFHLFCPT", "length": 515 }, "evidence": [ { "id": "E1BDE8", "url": "https://omabrowser.org/oma/group/E1BDE8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O08674-1", "protein_name": "Recombining binding protein suppressor of hairless-like protein", "gene_name": "Rbpjl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPRETTDPSLPPGPLTHLSLPDSSEVRLQSDGPSLLGSWTRSPPEHAIILREGVRTCLQQRCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPMQDQALQSAETGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGQELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPSDTPGGAGTYLCLATEKVVRFQASLCPKEANRALLNDSSCWTIIGTESVEFTFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSPFSFTYTPEYSALPRLPNAQEPAPDADTLLESIHHEFTRTNFHLFCPT", "length": 515 }, "evidence": [ { "id": "E1BDE8", "url": "https://omabrowser.org/oma/group/E1BDE8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UBG7-1", "protein_name": "Recombining binding protein suppressor of hairless-like protein", "gene_name": "RBPJL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPAGAADPSVPPNPLTHLSLQDRSEMQLQSEADRRSLPGTWTRSSPEHTTILRGGVRRCLQQQCEQTVRILHAKVAQKSYGNEKRFFCPPPCVYLSGPGWRVKPGQDQAHQAGETGPTVCGYMGLDSASGSATETQKLNFEQQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHSAQGDFPPREGYVRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGSPPGGGGTYLCLATEKVVQFQASPCPKEANRALLNDSSCWTIIGTESVEFSFSTSLACTLEPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFCSDWRWLRAPITIPMSLVRADGLFYPSAFSFTYTPEYSVRPGHPGVPEPATDADALLESIHQEFTRTNFHLFIQT", "length": 517 }, "evidence": [ { "id": "E1BDE8", "url": "https://omabrowser.org/oma/group/E1BDE8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E1BDE8", "url": "https://www.uniprot.org/uniprotkb/E1BDE8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BDE8", "url": "https://www.uniprot.org/uniprotkb/E1BDE8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BDE8", "url": "https://www.uniprot.org/uniprotkb/E1BDE8" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BDE8", "url": "https://www.uniprot.org/uniprotkb/E1BDE8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BDE8", "url": "https://www.uniprot.org/uniprotkb/E1BDE8" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "E1BDE8", "url": "https://www.uniprot.org/uniprotkb/E1BDE8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BDE8", "url": "https://www.uniprot.org/uniprotkb/E1BDE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDE8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 517, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDE8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDE8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDE8" }, { "id": "SM01268", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-trefoil DNA-binding", "eco_id": "ECO_0000259", "start_pos": 206, "end_pos": 358, "start_aa": "Leu", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDE8" }, { "id": "SM01267", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01267" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RBP-J/Cbf11/Cbf12 DNA binding", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 205, "start_aa": "Thr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDG1-1", "uniprot_ac": "E1BDG1", "uniprot_id": "E1BDG1_BOVIN", "mass": { "chemical_mass": 35869.0, "monoisotopic_mass": 35869.0 }, "refseq": { "ac": "NP_001376939", "name": "olfactory receptor family 52 subfamily AB member 4", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376939" }, "gene_names": [ { "name": "OR52AB4", "type": "recommended", "evidence": [ { "id": "E1BDG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG1" } ] }, { "name": "OR52AB4B", "type": "synonym", "evidence": [ { "id": "E1BDG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG1" } ] }, { "name": "OR52AB4", "type": "synonym", "evidence": [ { "id": "NP_001376939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376939" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BDG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 52 subfamily AB member 4", "type": "synonym", "evidence": [ { "id": "NP_001376939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376939" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BDG1", "url": "https://www.uniprot.org/uniprotkb/E1BDG1#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"" }, { "name": "beta-lactamase activity", "id": "GO:0008800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008800", "evidence": [ { "database": "UniProtKB", "id": "E1BDI1", "url": "https://www.uniprot.org/uniprotkb/E1BDI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20401", "name": "", "equation": "a beta-lactam + H2O = a substituted beta-amino acid", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3SZM7-1", "A5PJT0-1", "A0AAA9RZT6-1", "E1BDI1-1", "E1BIR2-1", "A0AAA9TZA4-1" ], "evidence": [ { "id": "20401", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20401" } ] }, { "id": "48616", "name": "", "equation": "leukotriene D4 + H2O = leukotriene E4 + glycine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3SZM7-1", "E1BDI1-1", "E1BIR2-1" ], "evidence": [ { "id": "48616", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48616" } ] }, { "id": "48940", "name": "", "equation": "an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3SZM7-1", "E1BIR2-1", "E1BDI1-1" ], "evidence": [ { "id": "48940", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48940" } ] }, { "id": "60520", "name": "", "equation": "L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3SZM7-1", "E1BDI1-1", "E1BIR2-1" ], "evidence": [ { "id": "60520", "database": 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"MAIPFAPSRGAGAANRRWLVLLPPLLLALLLSRPAAALVEGLYCGTRDCYEVLGVSRMASKAEIARAYRQLARRYHPDRYRPEPGEEGPGLTPQSAEEAFLLVATAYETLKDEETRKDYDYMLDHPEEYYSHYYHYYSRRLAPKVDVRVVILVSVCAISVFQFFSWWNSYDKTISYLATVPKYRIQAMEIAKQQGLLRKAKEKGRNKKSKEEVRDEEENIIKNIIKSKIDIKGGYQKPQIRDLLLFQILLAPFHLCSYIVWYCRWIYNFNIKGKEYGEEERLYIIRKSMKMSKSQFDSLEDHQKETFLKRELWIKENYEVYKQEQEEELKKRLANDPRWKRYRRWMKNEGPGRLTFVDD", "length": 359, "header": "tr|E1BDJ7-1|E1BDJ7_BOVIN Isoform 1 of DnaJ homolog subfamily C member 25 OS=Bos taurus OX=9913 GN=DNAJC25 PE=3 SV=2 CANONICAL=E1BDJ7-1" }, "isoforms": [ { "isoform_ac": "E1BDJ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BDJ7/entry#E1BDJ7-1", "sequence": { "sequence": "MAIPFAPSRGAGAANRRWLVLLPPLLLALLLSRPAAALVEGLYCGTRDCYEVLGVSRMASKAEIARAYRQLARRYHPDRYRPEPGEEGPGLTPQSAEEAFLLVATAYETLKDEETRKDYDYMLDHPEEYYSHYYHYYSRRLAPKVDVRVVILVSVCAISVFQFFSWWNSYDKTISYLATVPKYRIQAMEIAKQQGLLRKAKEKGRNKKSKEEVRDEEENIIKNIIKSKIDIKGGYQKPQIRDLLLFQILLAPFHLCSYIVWYCRWIYNFNIKGKEYGEEERLYIIRKSMKMSKSQFDSLEDHQKETFLKRELWIKENYEVYKQEQEEELKKRLANDPRWKRYRRWMKNEGPGRLTFVDD", "length": 359, "header": "tr|E1BDJ7-1|E1BDJ7_BOVIN Isoform 1 of DnaJ homolog subfamily C member 25 OS=Bos taurus OX=9913 GN=DNAJC25 PE=3 SV=2 CANONICAL=E1BDJ7-1" }, "locus": { "chromosome": "8", "start_pos": 101073054, "end_pos": 101055896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011980.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011980.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011980.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011980.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:535430", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535430", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2ALW5-1", "protein_name": "DnaJ homolog subfamily C member 25", "gene_name": "Dnajc25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAARLALRGGPGAAGQRPWLLLAPLLLVPLLARPAEALVEGLYCGTRDCYEVLGVSRSASKAEIARAYRQLARRYHPDRYRPEPGDGPGGAPPSAEAFLLVATAYETLKDEETRKDYDYMLDHPEEYYSHYYHYYSRRLAPKVDVRVVILVSVCAISMFQYFSWWNSYNKAISYLATVPKYRIQATEIAKEQGLLKKAKEKGKNKKSKEEIRDEEENIIKNIIKSKIDIKGGYQKPQVRDLLLFQVILAPVHLCSYIAWYCRWIYNFNIKGKEYGEEERLYIIRKSMKMSQSQFDSLEDHQKEMFLKRELWIKENYEVYKQEQEEELKKKLANDPRWKRYRRWMKNEGPGRLTFVDD", "length": 357 }, "evidence": [ { "id": "E1BDJ7", "url": "https://omabrowser.org/oma/group/E1BDJ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1NCU8-1", "protein_name": "DnaJ homolog subfamily C member 25", "gene_name": "DNAJC25", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAGGRRWLLCLWLSAALLLPRPARGLIEGLYCGRRVCYEVLGVGRQASKAEIARAYRQLARQYHPDRYRGEPAAAGGSQAAHEKFLLIATAYETLKDEETRKDYDYMLDHPEEYYRHYYHYYSRRLAPKVDVRIVILVTVCAISVFQFFSWWSSYNEAINYLATVPKYRIQATEIAKQQGLLNKTREKGKNRRSKEEIREEEEEIIKDIIKNKIDIKGGYQKPKIYDILLFQILLAPFYLCKYVIWYCWWIYCFTIKGQEYGVEEKLYIIRRYMKMSQSQFDSLEDHQKETFLERQLWIRENYEVYKQEQEEELKKKMAMDPRWKRYRRWMRNEGPGRLTFIDD", "length": 346 }, "evidence": [ { "id": "E1BDJ7", "url": "https://omabrowser.org/oma/group/E1BDJ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5BJW9-1", "protein_name": "DnaJ homolog subfamily C member 25", "gene_name": "Dnajc25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAARLAWRRGPGAAGQRPWLLLAPLLLVPLLVRPAEALVEGLYCGTRDCYEVLGVSRSASKAEIARAYRQLARRYHPDRYRPEPGDGPGGAPPSAEAFLLVATAYETLKDEETRKDYDYMLDHPEEYYSHYYHYYSRRLAPKVDVRVVILVSVCAISVFQYFSWWNSYNKSISYLATVPKYRIQATEIAKEQGLLKKAKEKGKNKKSKEEIRDEEENIIKNIIKSKIDIKGGYQKPQVRDLLLFQVLLAPVHLCSYIAWYCRWVYNFNIKGKEYGEEERLYIIRKSMKMSQSQFDSLEDHQKEMFLKRELWIKENYEVYKQEQEEELKKKLANDPRWKRYRRWMKNEGPGRLTFVDD", "length": 357 }, "evidence": [ { "id": "E1BDJ7", "url": "https://omabrowser.org/oma/group/E1BDJ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8GUN6-1", "protein_name": "Chaperone protein dnaJ 50", "gene_name": "C50", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPPVTERWCLALILLFLSLFVQSSTAIYCGAEDCYALLGVAQDANASDIKRSYYKLSLQHHPDKNPDPESRKLFVKIATAYEILKDNTTRAQYDYAIEHPEEVFYNTAQYYRAKYGHKSDPRAVLVGLLVVLSAFQYLNNVARYNEAIATVKRTPAYKNKLKALELERTGGVSNKKKGSKQIDQKLQEELSNELDLQIKGAEKPSVWELLGVRFILLPYTIIKLLVWYSSWVWRYKVKKAPYSWEDASYLTRRSLSVPADAWANLDEYRKEDLVQKRLWEKQNLENYFAEMRKESKRRR", "length": 300 }, "evidence": [ { "id": "E1BDJ7", "url": "https://omabrowser.org/oma/group/E1BDJ7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9H1X3-1", "protein_name": "DnaJ homolog subfamily C member 25", "gene_name": "DNAJC25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAPLLSPGWGAGAAGRRWWMLLAPLLPALLLVRPAGALVEGLYCGTRDCYEVLGVSRSAGKAEIARAYRQLARRYHPDRYRPQPGDEGPGRTPQSAEEAFLLVATAYETLKDEETRKDYDYMLDHPEEYYSHYYHYYSRRLAPKVDVRVVILVSVCAISVFQFFSWWNSYNKAISYLATVPKYRIQATEIAKQQGLLKKAKEKGKNKKSKEEIRDEEENIIKNIIKSKIDIKGGYQKPQICDLLLFQIILAPFHLCSYIVWYCRWIYNFNIKGKEYGEEERLYIIRKSMKMSKSQFDSLEDHQKETFLKRELWIKENYEVYKQEQEEELKKKLANDPRWKRYRRWMKNEGPGRLTFVDD", "length": 360 }, "evidence": [ { "id": "E1BDJ7", "url": "https://omabrowser.org/oma/group/E1BDJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VXT2-1", "protein_name": "DnaJ homolog subfamily C member 25 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRTHGLRLVLLALLPTMALGLLEGLYCGKENCYDVLGVTRESSKSEIGKAYRQLARRYHPDLHRGAEAKAAAETQFKLVATAYEILRDEESRTDYDYMLDNPDAYYAHYYRYYRRRVAPKVDVRVVIVVVLTIVSVIQYYSGWQRYDSAIKYFATVPKYRNQALEIARDEIQEKIQKKGKNRMSKNDQRDELERIIRRVIEEKMDVKGGYAKPTLWDVLWVQLIICPYTILSFIVWHAQWFWRYTVMKQPYGREQKLYLIRRHLGMGQHQFEAQEDKLIEEYLHLKLWKRENFVAWKAEQEEEMKKKLAENPRYKAYRRYMKNHGPGRITFED", "length": 333 }, "evidence": [ { "id": "E1BDJ7", "url": "https://omabrowser.org/oma/group/E1BDJ7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BDJ7", "url": "https://www.uniprot.org/uniprotkb/E1BDJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "E1BDJ7", "url": "https://www.uniprot.org/uniprotkb/E1BDJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDJ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 359, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDJ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDJ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDJ7" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 123, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDK3-1", "uniprot_ac": "E1BDK3", "uniprot_id": "E1BDK3_BOVIN", "mass": { "chemical_mass": 38857.0, "monoisotopic_mass": 38857.0 }, "refseq": {}, "gene_names": [ { "name": "NAA30", "type": "recommended", "evidence": [ { "id": "E1BDK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK3" } ] } ], "protein_names": [ { "name": "N-alpha-acetyltransferase 30", "type": "recommended", "evidence": [ { "id": "E1BDK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK3/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.256", "type": "synonym", "evidence": [ { "id": "E1BDK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK3/entry#names_and_taxonomy" } ] }, { "name": "N-acetyltransferase 12", "type": "synonym", "evidence": [ { "id": "E1BDK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK3/entry#names_and_taxonomy" } ] }, { "name": "N-acetyltransferase MAK3 homolog", "type": "synonym", "evidence": [ { "id": "E1BDK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK3/entry#names_and_taxonomy" } ] }, { "name": "NatC catalytic subunit", "type": "synonym", "evidence": [ { "id": "E1BDK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. N-terminal acetylation protects proteins from ubiquitination and degradation by the N-end rule pathway. Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate.", "evidence": [ { "database": "UniProtKB", "id": "E1BDK3", "url": "https://www.uniprot.org/uniprotkb/E1BDK3#function" }, { "database": "UniProtKB", "id": "ARBA00057654", "url": "https://www.uniprot.org/uniprotkb/ARBA00057654#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDK3", "url": "https://www.uniprot.org/uniprotkb/E1BDK3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NAA30", "url": "https://www.uniprot.org/uniprotkb/E1BDK3", "locus": { "chromosome": "10", "start_pos": 69789526, "end_pos": 69768121, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012998", "url": "https://www.ensembl.org/id/ENSBTAG00000012998" } ] } } ], "crossref": [ { "id": "E1BDK3", "url": "https://alphafold.ebi.ac.uk/entry/E1BDK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012998", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012998", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04301", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04301", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BDK3", "url": "https://www.orthodb.org/?gene=E1BDK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45896", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45896", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45896:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45896:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00583", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00583", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "50520", "url": "https://www.rhea-db.org/rhea/50520", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50524", "url": "https://www.rhea-db.org/rhea/50524", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50528", "url": "https://www.rhea-db.org/rhea/50528", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50532", "url": "https://www.rhea-db.org/rhea/50532", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50560", "url": "https://www.rhea-db.org/rhea/50560", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BDK3", "url": "https://www.uniprot.org/uniprotkb/E1BDK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDK3-1", "url": "https://www.uniprot.org/uniprotkb/E1BDK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ALAAAEVPPGPSSLLPPPAPSASAAAEPRCPFSAGAALACCSEDEEDDEEHEGGGCGGSPAGGEAAAKGHPCLRCPQPPQEQLQLNGLINPELRHLRAAASLKSKVLSSAEAATIAATPDGGPRATATKGAGVHSGESPPHCLPSNARTALSSPAEAAAASDPAAARNGLAEGTEQEEEEDEQVRLLASSLTAGCSLRSPSGREVEPGEDRTIRYVRYESELQMPDIMRLITKDLSEPYSIYTYRYFIHNWPQLCFLAMVGEECVGAIVCKLDMHKKMFRRGYIAMLAVDSKYRRNGIGTNLVKKAIYAMVEGDCDEVVLETEITNKSALKLYENLGFVRDKRLFRYYLNGVDALRLKLWLR", "length": 362, "header": "tr|E1BDK3-1|E1BDK3_BOVIN Isoform 1 of N-alpha-acetyltransferase 30 OS=Bos taurus OX=9913 GN=NAA30 PE=3 SV=2 CANONICAL=E1BDK3-1" }, "isoforms": [ { "isoform_ac": "E1BDK3-1", "url": "https://www.uniprot.org/uniprotkb/E1BDK3/entry#E1BDK3-1", "sequence": { "sequence": "ALAAAEVPPGPSSLLPPPAPSASAAAEPRCPFSAGAALACCSEDEEDDEEHEGGGCGGSPAGGEAAAKGHPCLRCPQPPQEQLQLNGLINPELRHLRAAASLKSKVLSSAEAATIAATPDGGPRATATKGAGVHSGESPPHCLPSNARTALSSPAEAAAASDPAAARNGLAEGTEQEEEEDEQVRLLASSLTAGCSLRSPSGREVEPGEDRTIRYVRYESELQMPDIMRLITKDLSEPYSIYTYRYFIHNWPQLCFLAMVGEECVGAIVCKLDMHKKMFRRGYIAMLAVDSKYRRNGIGTNLVKKAIYAMVEGDCDEVVLETEITNKSALKLYENLGFVRDKRLFRYYLNGVDALRLKLWLR", "length": 362, "header": "tr|E1BDK3-1|E1BDK3_BOVIN Isoform 1 of N-alpha-acetyltransferase 30 OS=Bos taurus OX=9913 GN=NAA30 PE=3 SV=2 CANONICAL=E1BDK3-1" }, "locus": { "chromosome": "10", "start_pos": 69786183, "end_pos": 69768320, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017282.8", "url": "https://www.ensembl.org/id/ENSBTAT00000017282.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017282.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017282.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BDK3", "url": "https://www.uniprot.org/uniprotkb/E1BDK3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BDK3", "url": "https://www.uniprot.org/uniprotkb/E1BDK3" } ], "pmid": "" }, { "name": "NatC complex", "id": "GO:0031417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031417", "evidence": [ { "database": "UniProtKB", "id": "E1BDK3", "url": "https://www.uniprot.org/uniprotkb/E1BDK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "E1BDK3", "url": "https://www.uniprot.org/uniprotkb/E1BDK3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-N-terminal amino-acid acetyltransferase activity", "id": "GO:0004596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004596", "evidence": [ { "database": "UniProtKB", "id": "E1BDK3", "url": "https://www.uniprot.org/uniprotkb/E1BDK3" } ], "pmid": "" }, { "name": "protein N-terminal-methionine acetyltransferase activity", "id": "GO:0120518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120518", "evidence": [ { "database": "UniProtKB", "id": "E1BDK3", "url": "https://www.uniprot.org/uniprotkb/E1BDK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "50520", "name": "", "equation": "N-terminal L-methionyl-L-leucyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-leucyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0IIJ0-1", "E1BDK3-1" ], "evidence": [ { "id": "50520", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50520" } ] }, { "id": "50524", "name": "", "equation": "N-terminal L-methionyl-L-isoleucyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-isoleucyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BDK3-1" ], "evidence": [ { "id": "50524", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50524" } ] }, { "id": "50528", "name": "", "equation": "N-terminal L-methionyl-L-phenylalanyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-phenylalanyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0IIJ0-1", "E1BDK3-1" ], "evidence": [ { "id": "50528", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50528" } ] }, { "id": "50532", "name": "", "equation": "N-terminal L-methionyl-L-tyrosyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-tyrosyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0IIJ0-1", "E1BDK3-1" ], "evidence": [ { "id": "50532", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50532" } ] }, { "id": "50560", "name": "", "equation": "N-terminal L-methionyl-L-tryptophyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-tryptophyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BDK3-1" ], "evidence": [ { "id": "50560", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50560" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BDK3", "gene_name": "NAA30", "activity": [ { "ec_number": "2.3.1.256", "activity": "N-terminal L-methionyl-L-tryptophyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-tryptophyl-[protein] + CoA + H(+).", "evidence": [ { "id": "E1BDK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK3" } ] }, { "ec_number": "2.3.1.256", "activity": "", "evidence": [ { "id": "E1BDK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK3" } ] } ] }, { "uniprot_ac": "Q0IIJ0", "gene_name": "NAA50", "activity": [ { "ec_number": "2.3.1.258", "activity": "N-terminal L-methionyl-L-threonyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-threonyl-[protein] + CoA + H(+).", "evidence": [ { "id": "Q0IIJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIJ0" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q0IIJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIJ0" } ] }, { "ec_number": "2.3.1.258", "activity": "", "evidence": [ { "id": "Q0IIJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIJ0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDK3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 362, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDK3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDK3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK3" }, { "id": "PS51186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 214, "end_pos": 362, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.256", "ec_name": "N-terminal L-methionyl-L-tryptophyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-tryptophyl-[protein] + CoA + H(+).", "evidence": [ { "id": "2.3.1.256", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.256" }, { "id": "2.3.1.256", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.256" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 326, "end_pos": 328 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDK9-1", "uniprot_ac": "E1BDK9", "uniprot_id": "E1BDK9_BOVIN", "mass": { "chemical_mass": 66777.0, "monoisotopic_mass": 66777.0 }, "refseq": { "ac": "NP_001095749", "name": "all-trans-retinol 13,14-reductase precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001095749" }, "gene_names": [ { "name": "RETSAT", "type": "recommended", "evidence": [ { "id": "E1BDK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK9" } ] }, { "name": "RETSAT", "type": "synonym", "evidence": [ { "id": "NP_001095749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001095749" } ] } ], "protein_names": [ { "name": "All-trans-retinol 13,14-reductase", "type": "recommended", "evidence": [ { "id": "E1BDK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK9/entry#names_and_taxonomy" } ] }, { "name": 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"https://www.ncbi.nlm.nih.gov/protein/NP_001095749" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDK9", "url": "https://www.uniprot.org/uniprotkb/E1BDK9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RETSAT", "url": "https://www.uniprot.org/uniprotkb/E1BDK9", "locus": { "chromosome": "11", "start_pos": 49656929, "end_pos": 49642200, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021934", "url": "https://www.ensembl.org/id/ENSBTAG00000021934" } ] } } ], "crossref": [ { "id": "E1BDK9", "url": "https://alphafold.ebi.ac.uk/entry/E1BDK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021934", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021934", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "614455", "url": "https://www.ncbi.nlm.nih.gov/gene/614455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614455", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614455", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFMFADW", "url": "https://omabrowser.org/oma/group/AFMFADW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BDK9", "url": "https://www.orthodb.org/?gene=E1BDK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46091", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46091", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46091:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46091:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001095749", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001095749", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19193", "url": "https://www.rhea-db.org/rhea/19193", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BDK9", "url": "https://www.uniprot.org/uniprotkb/E1BDK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDK9-1", "url": "https://www.uniprot.org/uniprotkb/E1BDK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWVSLLLLAALLLVVLGKVYKGLFSGSSPNPFLEDVQRPPAPLVTDKEARKKVLKQAFSVSRVPKKLDVVVIGSGFGGLAAAAILAKTGKRVLVLEQHTKAGGCCHTFGKNGLEFDTGIHYIGRMQEGSFDRFILDQITEGQLDWAALSSPFDIMVLEGPDGRKEFPMYTGMKAYIQGLKDKFPQEEAAIDKYMKLVKVVSRGGIYAVLLKILPLPVAQLLTKYGLLTYFSPFLRASTQSLAEVLQQLPASPELQAVLSYIFPTYGVTPSHTTFSMHALLVDYFLGGAFYPRGGSSEIAFHTIPVIQRAGGAVLTRAPVHSILLDSAGKACGVTVKKGEDLVNIYCPIVISDAGLFNTYEHLLPEQARCLPGVKRQLGMVRPGLSMFCVFICLRGTKEDLGLPTTNYYIYFDKDMDRAMEHYVSLPGDKAAAHMPLLFISFSSAKDPTWEDRYPDRSTAIILVPTSYEWFKEWRDEPQGKRSSAYENLKSSFVEAAVSVFLKQFPHLEGKVDSVTGGSPLSIQFYLAAPQGACYGADHDLGRLHPGAMASIRAQSPIPNLYLTGQDVLTCGLTGALQGALLCSSAILKRNLYLDLWKLGSRIQARKKKN", "length": 609, "header": "tr|E1BDK9-1|E1BDK9_BOVIN Isoform 1 of All-trans-retinol 13,14-reductase OS=Bos taurus OX=9913 GN=RETSAT PE=3 SV=1 CANONICAL=E1BDK9-1" }, "isoforms": [ { "isoform_ac": "E1BDK9-1", "url": "https://www.uniprot.org/uniprotkb/E1BDK9/entry#E1BDK9-1", "sequence": { "sequence": "MWVSLLLLAALLLVVLGKVYKGLFSGSSPNPFLEDVQRPPAPLVTDKEARKKVLKQAFSVSRVPKKLDVVVIGSGFGGLAAAAILAKTGKRVLVLEQHTKAGGCCHTFGKNGLEFDTGIHYIGRMQEGSFDRFILDQITEGQLDWAALSSPFDIMVLEGPDGRKEFPMYTGMKAYIQGLKDKFPQEEAAIDKYMKLVKVVSRGGIYAVLLKILPLPVAQLLTKYGLLTYFSPFLRASTQSLAEVLQQLPASPELQAVLSYIFPTYGVTPSHTTFSMHALLVDYFLGGAFYPRGGSSEIAFHTIPVIQRAGGAVLTRAPVHSILLDSAGKACGVTVKKGEDLVNIYCPIVISDAGLFNTYEHLLPEQARCLPGVKRQLGMVRPGLSMFCVFICLRGTKEDLGLPTTNYYIYFDKDMDRAMEHYVSLPGDKAAAHMPLLFISFSSAKDPTWEDRYPDRSTAIILVPTSYEWFKEWRDEPQGKRSSAYENLKSSFVEAAVSVFLKQFPHLEGKVDSVTGGSPLSIQFYLAAPQGACYGADHDLGRLHPGAMASIRAQSPIPNLYLTGQDVLTCGLTGALQGALLCSSAILKRNLYLDLWKLGSRIQARKKKN", "length": 609, "header": "tr|E1BDK9-1|E1BDK9_BOVIN Isoform 1 of All-trans-retinol 13,14-reductase OS=Bos taurus OX=9913 GN=RETSAT PE=3 SV=1 CANONICAL=E1BDK9-1" }, "locus": { "chromosome": "11", "start_pos": 49655598, "end_pos": 49642240, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029241.6", "url": "https://www.ensembl.org/id/ENSBTAT00000029241.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029241.4", "url": "https://www.ensembl.org/id/ENSBTAP00000029241.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 268, "start_aa": "Thr", "end_pos": 268, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr268", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:614455", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614455", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SVB2-1", "protein_name": "All-trans-retinol 13,14-reductase", "gene_name": "RETSAT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWLSLLLLAALLLAVLGQVYKWLFAGSSPNPFSEDVKRPPAPLVTDKEARKKVLKQVFSVNRVPEKLDVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKAGGCCHTFGKDGLEFDTGIHYIGRMEEGSFGRFILDQITEGQLDWATLSSPFDIMVLDGPNGRKEFPMYTGKKAYVQGLKEKFPQEEAAIDKYIKLVKMVSSRASHAILLKILPLPLAQFLSKYGLLTRFSPFLRASTQSLAKVLQQLPASPELRAVLSYIFPTYGVTPSHSTFAMHALLVDHYLKGAFYPKGGTSEIAFHTIPVIQRAGGAVLTRAPVQSILLDSAGKACGVAVKNGQELVNIFCPVVISDAGLFNTYEHLLPEKARSLPGVQRQLGAVRPGLSIFSVFICLRGTKKDLGLWSTNYYVYFDTDMDKAMEHYLSLPRDKAAAHMPLLFIASPSSKDPTWEDRFPDRSTLIVLVPTSYEWFEEWRDEPKGKRSSDYETLKSSFVEASLSVVLKLFPQLEGKVDSVTGGSPLTTQFYLAAPRGACYGADHDLSRLHPHVMASMRAQSPIPNLYLTGQDIFTCGLMGALQGALLCSGAILKRNLYSDLWKLGSKIQAQKNKKKN", "length": 611 }, "evidence": [ { "id": "E1BDK9", "url": "https://omabrowser.org/oma/group/E1BDK9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5BLE8-1", "protein_name": "All-trans-retinol 13,14-reductase", "gene_name": "retsat", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWFAVVAIFLALVAFLYRYVVGSGPNPFAIDTREPLKPMVFDRKLKNKVLKQGFLASRVPEDLDAVVVGSGIGGLAIAVLLAKVGKKVLVLEQHDRAGGCCHTFKEQGFEFDVGIHYIGELSNHKPLRCIIDQMTNGQLQWDPLENPFDNVVIGPPENRRIYQIYSGRKRYMDELKKCFPGEEKAIDEYVRLCKEVGQGVWVMVLLKFLPTPIANFLVRTGLANRLTSFSRYASRSLTDVVNELTQNKDLRAVLSYIFGTYGKIPKEASFSMHSLIVNHYMNGAWYPKGGATEIAYHMIPIIEKAGGAVLVRAPVNRILLNDAKEAIGVSVLKGQEEVHVRAPIVISDAGIFNTYEYLLPKDVQTMPAIQKQLSMLQHGDSGLSIFIGLDGTKEELGLKADNYFIYPENNIDELLEDYRSGNREESAKKNPLIFVASPSAKDSTWPERTPGKSTLTVVSFANYEWFEEWKDDKVKNRSTDYKQLKELFINYILEAVTEIYPKIKDRIEYVDAGTPITNQHYIAAPRGEIYGADHGIPRFSAELNATIRAQTPIKNLYLTGQDLMLCGFAGALTGALTCGSVILNRNLHLEAFSLAKRVQNGNNKKKT", "length": 607 }, "evidence": [ { "id": "E1BDK9", "url": "https://omabrowser.org/oma/group/E1BDK9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q64FW2-1", "protein_name": "All-trans-retinol 13,14-reductase", "gene_name": "Retsat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWITALLLAVLLLVILHRVYVGLYAASSPNPFAEDVKRPPEPLVTDKEARKKVLKQAFSVSRVPEKLDAVVIGSGIGGLASAAVLAKAGKRVLVLEQHTKAGGCCHTFGENGLEFDTGIHYIGRMREGNIGRFILDQITEGQLDWAPMASPFDLMILEGPNGRKEFPMYSGRKEYIQGLKKKFPKEEAVIDKYMELVKVVARGVSHAVLLKFLPLPLTQLLSKFGLLTRFSPFCRASTQSLAEVLQQLGASRELQAVLSYIFPTYGVTPSHTAFSLHALLVDHYIQGAYYPRGGSSEIAFHTIPLIQRAGGAVLTRATVQSVLLDSAGRACGVSVKKGQELVNIYCPVVISNAGMFNTYQHLLPETVRHLPDVKKQLAMVRPGLSMLSIFICLKGTKEDLKLQSTNYYVYFDTDMDKAMERYVSMPKEKAPEHIPLLFIAFPSSKDPTWEERFPDRSTMTALVPMAFEWFEEWQEEPKGKRGVDYETLKNAFVEASMSVIMKLFPQLEGKVESVTGGSPLTNQYYLAAPRGATYGADHDLARLHPHAMASIRAQTPIPNLYLTGQDIFTCGLMGALQGALLCSSAILKRNLYSDLQALGSKVKAQKKKM", "length": 609 }, "evidence": [ { "id": "E1BDK9", "url": "https://omabrowser.org/oma/group/E1BDK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VHE9-1", "protein_name": "All-trans-retinol 13,14-reductase", "gene_name": "Retsat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWITALLLVVLLLVVVHRVYVGLFTGSSPNPFAEDVKRPPEPLVTDKEARKKVLKQAFSVSRVPEKLDAVVIGSGIGGLASAAVLAKAGKRVLVLEQHTKAGGCCHTFGENGLEFDTGIHYIGRMREGNIGRFILDQITEGQLDWAPMASPFDLMILEGPNGRKEFPMYSGRKEYIQGLKEKFPKEEAVIDKYMELVKVVAHGVSHAILLKFLPLPLTQLLNKFGLLTRFSPFCRASTQSLAEVLKQLGASPELQAVLSYILPTYGVTPSHTTFSLHALLVDHYIQGAYYPRRGSSEIAFHTIPLIQRAGGAVLTRATVQSVLLDSAGRACGVSVKKGQELVNIYCPVVISNAGMFNTYQHLLPESVRYLPDVKKQLTMVKPGLSMLSIFICLKGTKEELKLQSTNYYVYFDTDMDKAMECYVSMPKEKAPEHIPLLFIPFPSSKDPTWEDRFPDRSTMTVLVPTAFEWFEEWQEEPKGKRGVDYETLKNTFREASMSVIMKLFPQLEGKVESVTGGSPLTNQYYLAAHRGATYGADHDLARLHPHAMASLRAQTPIPNLYLTGQDIFTCGLMGALQGALLCSSAILKRNLYSDLQALGSKVRAQKKKK", "length": 609 }, "evidence": [ { "id": "E1BDK9", "url": "https://omabrowser.org/oma/group/E1BDK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BDK9", "url": "https://www.uniprot.org/uniprotkb/E1BDK9" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "E1BDK9", "url": "https://www.uniprot.org/uniprotkb/E1BDK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retinol metabolic process", "id": "GO:0042572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042572", "evidence": [ { "database": "UniProtKB", "id": "E1BDK9", "url": "https://www.uniprot.org/uniprotkb/E1BDK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "all-trans-retinol 13,14-reductase activity", "id": "GO:0051786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051786", "evidence": [ { "database": "UniProtKB", "id": "E1BDK9", "url": "https://www.uniprot.org/uniprotkb/E1BDK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19193", "name": "", "equation": "all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BDK9-1" ], "evidence": [ { "id": "19193", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19193" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BDK9", "gene_name": "RETSAT", "activity": [ { "ec_number": "1.3.99.23", "activity": "all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH2.", "evidence": [ { "id": "E1BDK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK9" } ] }, { "ec_number": "1.3.99.23", "activity": "", "evidence": [ { "id": "E1BDK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDK9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDK9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 609, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDK9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDK9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.3.99.23", "ec_name": "all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH2.", "evidence": [ { "id": "1.3.99.23", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.99.23" }, { "id": "1.3.99.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.3.99.23" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 268 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDM4-1", "uniprot_ac": "E1BDM4", "uniprot_id": "E1BDM4_BOVIN", "mass": { "chemical_mass": 50514.0, "monoisotopic_mass": 50514.0 }, "refseq": { "ac": "XP_010808818", "name": "fibrinogen C domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010808818" }, "gene_names": [ { "name": "FIBCD1", "type": "recommended", "evidence": [ { "id": "E1BDM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM4" } ] }, { "name": "FIBCD1", "type": "synonym", "evidence": [ { "id": "XP_010808818", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010808818" } ] } ], "protein_names": [ { "name": "Fibrinogen C domain containing 1", "type": "synonym", "evidence": [ { "id": "E1BDM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM4/entry#names_and_taxonomy" } ] }, { "name": "fibrinogen C domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_010808818", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010808818" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDM4", "url": "https://www.uniprot.org/uniprotkb/E1BDM4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FIBCD1", "url": "https://www.uniprot.org/uniprotkb/E1BDM4", "locus": { "chromosome": "11", "start_pos": 101147877, "end_pos": 101178873, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017982", "url": "https://www.ensembl.org/id/ENSBTAG00000017982" } ] } } ], "crossref": [ { "id": "E1BDM4", "url": "https://alphafold.ebi.ac.uk/entry/E1BDM4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017982", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017982", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "531723", "url": "https://www.ncbi.nlm.nih.gov/gene/531723", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:531723", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531723", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MVNERWK", "url": "https://omabrowser.org/oma/group/MVNERWK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BDM4", "url": "https://www.orthodb.org/?gene=E1BDM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010808818", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010808818", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BDM4", "url": "https://www.uniprot.org/uniprotkb/E1BDM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDM4-1", "url": "https://www.uniprot.org/uniprotkb/E1BDM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVNDRWKTMGGASQLEDRPRDKPQRPSCSYVLCTVLLSLAVLLAVAVTGAVLLLNHARVPGTAPPPVVSTGPAGANSALVTVDRADSSRLSILIDPRCPDLADGFARLEGAQASVLQALSQRQAELRLPGEQEQELLDTLADQLPRLLARASELQAECSGLRKGHGALGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDVLDALQRDRGLARPHVKADLQRAPARGSRPRGCANGSRPRDCLDVLLSGQQEDGVYSVFPTHDPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYRDGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMKFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 461, "header": "tr|E1BDM4-1|E1BDM4_BOVIN Isoform 1 of Fibrinogen C domain containing 1 OS=Bos taurus OX=9913 GN=FIBCD1 PE=4 SV=3 CANONICAL=E1BDM4-1" }, "isoforms": [ { "isoform_ac": "E1BDM4-1", "url": "https://www.uniprot.org/uniprotkb/E1BDM4/entry#E1BDM4-1", "sequence": { "sequence": "MVNDRWKTMGGASQLEDRPRDKPQRPSCSYVLCTVLLSLAVLLAVAVTGAVLLLNHARVPGTAPPPVVSTGPAGANSALVTVDRADSSRLSILIDPRCPDLADGFARLEGAQASVLQALSQRQAELRLPGEQEQELLDTLADQLPRLLARASELQAECSGLRKGHGALGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDVLDALQRDRGLARPHVKADLQRAPARGSRPRGCANGSRPRDCLDVLLSGQQEDGVYSVFPTHDPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYRDGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMKFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 461, "header": "tr|E1BDM4-1|E1BDM4_BOVIN Isoform 1 of Fibrinogen C domain containing 1 OS=Bos taurus OX=9913 GN=FIBCD1 PE=4 SV=3 CANONICAL=E1BDM4-1" }, "locus": { "chromosome": "11", "start_pos": 101178873, "end_pos": 101147914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023924.6", "url": "https://www.ensembl.org/id/ENSBTAT00000023924.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023924.5", "url": "https://www.ensembl.org/id/ENSBTAP00000023924.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:531723", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531723", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AH48-1", "protein_name": "Ficolin 3", "gene_name": "FCN3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGNERWKTMGGASQLEDGQQEKPQRMSCGYVLCTVLLSVAVLLAVTVTGAILFMNHYHTPVTEPPPVISTNPEEANALVTIEKADSSRINIFIDPNCPDPAGNVGRLEGLQGSLLRALAEHDAEAKATKGQQKALLLGVADEVAKLVTHAAQLRADCDGLKKGHSAMGQELSALQSEQGRLIQLLSESQTNMARLVSSVSDVLDTLQKERGGVRPRLKADLQRAPARGARPRGCSNGSRPRDCFDIYASGQQEDGIYSIFPTHYPSGFQVYCDMTTDGGGWTVFQRREDGSVNFFRGWEAYRDGFGKLTGEHWLGLKRIHVLTVQGSYELRVDLEDFDNGTAFAHYGSFGVGLFSVDPEEDGYPISISDYSGTAGDSFLKHNGMKFTTKDLDNDHSENNCAAFYHGAWWYRNCHTSNLNGQYLKGHHSSYADGIEWSSWTGWQYSLKFTEMKIRPVREEN", "length": 460 }, "evidence": [ { "id": "E1BDM4", "url": "https://omabrowser.org/oma/group/E1BDM4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2AV25-1", "protein_name": "Fibrinogen C domain-containing protein 1", "gene_name": "Fibcd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVHERWKTVGSASQLEDRPRDKPQRASCSYVLCTVLLSLAVLLAVAVTGVVLFLNHTHTPGTAPPPIVSTGTAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRALSEHQAQPRLDGAPELLDALADQLPRLLTRASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSIFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 459 }, "evidence": [ { "id": "E1BDM4", "url": "https://omabrowser.org/oma/group/E1BDM4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4ADA1-1", "protein_name": "Fibrinogen C domain containing 1", "gene_name": "Fibcd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVHERWKTVGGASQLEDRPRDKPQRAGCSYILCTVLLSLAVLLAVAVTGAVLFLNHAHAPGTAPPPIVSTGAAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRTLSEHQAQPRLDGAPELLDALADQLPRLLARASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGPHASYADGVEWSSWTGWQYSLKFSEMKIRPLREDR", "length": 459 }, "evidence": [ { "id": "E1BDM4", "url": "https://omabrowser.org/oma/group/E1BDM4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S0X3-1", "protein_name": "Fibrinogen C domain containing 1", "gene_name": "FIBCD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNDRWKTMGGASQLEDRPRDKPQRPSCGYVLCTVLLSLAVLLAVAVTGAVLFLNHAHAPGTAPPPIVSTGPAGANSALVTVDRADSSRLSILIDPRCPDLTDGFARLEGAQASVLQALSQRQAEPRLVGEQEQELLDTLADQLPRLLARASELQTECAGLRKGHSTLGQGLSSLQSEQGRLIQLLSESQGHMVHLVNSVSDVLDALQRDRGLGRPHVKADLQRAPARGSRPRGCANGSRPRDCLDVLLSGQQEDGVYSVFPTHDPAGFQVYCDMSTDGGGWTVFQRREDGSVNFFRGWEAYRDGFGKLTGEHWLGLKRLHALTTQAAYELHVDLEDFDNGTAYAHYRSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 461 }, "evidence": [ { "id": "E1BDM4", "url": "https://omabrowser.org/oma/group/E1BDM4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8N539-1", "protein_name": "Fibrinogen C domain-containing protein 1", "gene_name": "FIBCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNDRWKTMGGAAQLEDRPRDKPQRPSCGYVLCTVLLALAVLLAVAVTGAVLFLNHAHAPGTAPPPVVSTGAASANSALVTVERADSSHLSILIDPRCPDLTDSFARLESAQASVLQALTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTECMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 461 }, "evidence": [ { "id": "E1BDM4", "url": "https://omabrowser.org/oma/group/E1BDM4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BDM4", "url": "https://www.uniprot.org/uniprotkb/E1BDM4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BDM4", "url": "https://www.uniprot.org/uniprotkb/E1BDM4" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "E1BDM4", "url": "https://www.uniprot.org/uniprotkb/E1BDM4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BDM4", "url": "https://www.uniprot.org/uniprotkb/E1BDM4" } ], "pmid": "" }, { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "E1BDM4", "url": "https://www.uniprot.org/uniprotkb/E1BDM4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDM4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 461, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDM4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDM4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM4" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", "eco_id": "ECO_0000259", "start_pos": 235, "end_pos": 458, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 }, { "start_pos": 340, "end_pos": 342 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDP0-1", "uniprot_ac": "E1BDP0", "uniprot_id": "E1BDP0_BOVIN", "mass": { "chemical_mass": 84279.0, "monoisotopic_mass": 84279.0 }, "refseq": { "ac": "NP_001179524", "name": "leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179524" }, "gene_names": [ { "name": "LRFN2", "type": "recommended", "evidence": [ { "id": "E1BDP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDP0" } ] }, { "name": "LRFN2", "type": "synonym", "evidence": [ { "id": "NP_001179524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179524" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "E1BDP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDP0/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor", "type": "synonym", "evidence": [ { "id": "NP_001179524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179524" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDP0", "url": "https://www.uniprot.org/uniprotkb/E1BDP0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LRFN2", "url": "https://www.uniprot.org/uniprotkb/E1BDP0", "locus": { "chromosome": "23", "start_pos": 14301668, "end_pos": 14344021, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017971", "url": "https://www.ensembl.org/id/ENSBTAG00000017971" } ] } } ], "crossref": [ { "id": "E1BDP0", "url": "https://alphafold.ebi.ac.uk/entry/E1BDP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017971", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017971", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "524447", "url": "https://www.ncbi.nlm.nih.gov/gene/524447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524447", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524447", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELMDFSA", "url": "https://omabrowser.org/oma/group/ELMDFSA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BDP0", "url": "https://www.orthodb.org/?gene=E1BDP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8849932", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8849932", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179524", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179524", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BDP0", "url": "https://www.uniprot.org/uniprotkb/E1BDP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDP0-1", "url": "https://www.uniprot.org/uniprotkb/E1BDP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIAEEAFEDFLLTLEDLDLSYNNLHGLPWGSVRRMINLHQLSLDHNLLDHIAEGTFTDLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGAFTCIAANAAGEATATVEVSIVQLPHLSNSTSRAAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYTQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNQEGTGKPAAAVTNVHSQTNGAQPPALGSVPSGAPVPGPPKVVVRNELMDFSASLARGSDSSSSSSLGIGEGLGRGPWRLPPPAPRPKPNLDRLMGAFASLDLKSQRKEELLDSRTPGGRGSGTSAKGHPSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAATGGVAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESGLVGARGTFGSSEWVMESTV", "length": 787, "header": "tr|E1BDP0-1|E1BDP0_BOVIN Isoform 1 of Leucine-rich repeat and fibronectin type-III domain-containing protein 2 OS=Bos taurus OX=9913 GN=LRFN2 PE=3 SV=1 CANONICAL=E1BDP0-1" }, "isoforms": [ { "isoform_ac": "E1BDP0-1", "url": "https://www.uniprot.org/uniprotkb/E1BDP0/entry#E1BDP0-1", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIAEEAFEDFLLTLEDLDLSYNNLHGLPWGSVRRMINLHQLSLDHNLLDHIAEGTFTDLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGAFTCIAANAAGEATATVEVSIVQLPHLSNSTSRAAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYTQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNQEGTGKPAAAVTNVHSQTNGAQPPALGSVPSGAPVPGPPKVVVRNELMDFSASLARGSDSSSSSSLGIGEGLGRGPWRLPPPAPRPKPNLDRLMGAFASLDLKSQRKEELLDSRTPGGRGSGTSAKGHPSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAATGGVAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESGLVGARGTFGSSEWVMESTV", "length": 787, "header": "tr|E1BDP0-1|E1BDP0_BOVIN Isoform 1 of Leucine-rich repeat and fibronectin type-III domain-containing protein 2 OS=Bos taurus OX=9913 GN=LRFN2 PE=3 SV=1 CANONICAL=E1BDP0-1" }, "locus": { "chromosome": "23", "start_pos": 14344021, "end_pos": 14302058, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023907.5", "url": "https://www.ensembl.org/id/ENSBTAT00000023907.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023907.3", "url": "https://www.ensembl.org/id/ENSBTAP00000023907.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:524447", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524447", "resource": "KEGG Pathway" }, { "id": "R-BTA-8849932", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8849932", "resource": "Reactome", "description": "Synaptic adhesion-like molecules" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C6G2-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "LRFN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEKLLCGILVFGMAVMVNACPKYCVCQNLSESLGTLCPSKGLLFVPLDIDRRTVELRLGGNFIINISRQDFANMSGLVDLTLSRNTISYIQPYSFTDLESLRSLHLDSNRLPDIGEDILRGLINLQHLILNNNQLTSISDEAFEDFLLTLEDLDLSYNNLRSIPWESIRKMINLHQLSLDHNLIDYITEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQVIPLAVTPFSPPLSLSFGGNPLHCNCELLWLRRLDRDDDMETCASPPGLKGRYFWYVREEEFVCEPPLITQHTHKLLVLEGQTATLKCKAIGDPTPIIHWVAPDDRLIGNSSRTSVYDNGTLDILITTSKDYGTFTCIAANAAGESTATIELSIVQLPHLSNGTGRAAPPKSRLSDITSSSKSNRGETKGPPERAVLVSEVTTTSALVKWTVSKSAPRVKMYQLQYNCSDDEVLIYRMIPATNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKEDYPQCQSMHSHFLGGTMILIIGGIIVATLLVFIVILMVRYKVCNNSQGKMSSVSNVYSQTNGAQPVQNGVLPQVNPKVVVRNELMEFNSGSVRSSISSSSSSMNSRDCDNYSLQSEQGTLSSKWRPPSRSKHNIDRLMGAFASLELKCQKKEETTDSRTSTAARHSDKEPLLGQPESKFRSLLMLPLEGKTKRSHSFDMGDFATSQCCTYPKKITNIWTKRSLSVNGMLLQYDDNDLTGAKGTYGSSEWVMESTV", "length": 763 }, "evidence": [ { "id": "E1BDP0", "url": "https://omabrowser.org/oma/group/E1BDP0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RVP3-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "LRFN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWGSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGAFTCIAANAAGEATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKAGDPQCQSMHSQILGGTVILVIGGTIVATLLVFIVILMVRYKVCNQEAPGKTAATVSNTHSQTNGAQPPAPSSTPSGAPVPGPPKAVVRNELVEFSASLARGSDSSSSSSLGFGEALGLGRGPWRLPPPAPRPKPNLDRLMGAFASLDLKSQRKEELLDSRTPGGRGSGTSARVHPSDREPLLGPPTARARSLLPLPLEGKAKRSHSFDMGDFAAAASAVGGVAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 791 }, "evidence": [ { "id": "E1BDP0", "url": "https://omabrowser.org/oma/group/E1BDP0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I1G3-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "Lrfn2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPNPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGAFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSAPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILIIGGIIVATLLVFIVILMVRYKVCNHDAPGKMAAATVSNVYSQTNGAQPPPLGGIPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLSRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAVAAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 788 }, "evidence": [ { "id": "E1BDP0", "url": "https://omabrowser.org/oma/group/E1BDP0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q460M5-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "Lrfn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLKTCGSPGGLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGPFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGAGEPPKSTPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHDAPGKMAAATVSNVYSQTNGAQPPPLGGMPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLSRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAAAAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEENDLVGARGTFGSSEWVMESTV", "length": 788 }, "evidence": [ { "id": "E1BDP0", "url": "https://omabrowser.org/oma/group/E1BDP0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80TG9-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "Lrfn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGSLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGPFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGAGEPPKSTPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHDTPGKMAAATVSNVYSQTNGSQPPPLGGIPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLGRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSSRGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAAAVPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 788 }, "evidence": [ { "id": "E1BDP0", "url": "https://omabrowser.org/oma/group/E1BDP0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULH4-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "LRFN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDIFITTSQDSGAFTCIAANAAGEATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSEVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHEAPSKMAAAVSNVYSQTNGAQPPPPSSAPAGAPPQGPPKVVVRNELLDFTASLARASDSSSSSSLGSGEAAGLGRAPWRIPPSAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAAAGGVVPGGYSPPRKVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 789 }, "evidence": [ { "id": "E1BDP0", "url": "https://omabrowser.org/oma/group/E1BDP0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E1BDP0", "url": "https://www.uniprot.org/uniprotkb/E1BDP0" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "E1BDP0", "url": "https://www.uniprot.org/uniprotkb/E1BDP0" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "E1BDP0", "url": "https://www.uniprot.org/uniprotkb/E1BDP0" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "E1BDP0", "url": "https://www.uniprot.org/uniprotkb/E1BDP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "E1BDP0", "url": "https://www.uniprot.org/uniprotkb/E1BDP0" } ], "pmid": "" }, { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "E1BDP0", "url": "https://www.uniprot.org/uniprotkb/E1BDP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDP0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 787, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDP0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDP0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDP0" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 421, "end_pos": 518, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BDP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDP0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 289, "end_pos": 375, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 29, "end_pos": 31 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 457, "end_pos": 459 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEJ9-1", "uniprot_ac": "E1BEJ9", "uniprot_id": "E1BEJ9_BOVIN", "mass": { "chemical_mass": 166386.0, "monoisotopic_mass": 166386.0 }, "refseq": {}, "gene_names": [ { "name": "GTF2H2", "type": "recommended", "evidence": [ { "id": "E1BEJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ] }, { "name": "NAIP", "type": "recommended", "evidence": [ { "id": "E1BEJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ] }, { "name": "GTF2H2", "type": "synonym", "evidence": [ { "id": "E1BEJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ] } ], "protein_names": [ { "name": "Ral transcription factor IIH, polypeptide 2, 44kDa", "type": "synonym", "evidence": [ { "id": "E1BEJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NAIP", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9", "locus": { "chromosome": "20", "start_pos": 10146540, "end_pos": 10176131, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003326", "url": "https://www.ensembl.org/id/ENSBTAG00000003326" } ] } } ], "crossref": [ { "id": "E1BEJ9", "url": "https://alphafold.ebi.ac.uk/entry/E1BEJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003326", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003326", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000027983", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000027983", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00022", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00022", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01453", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01453", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "511829", "url": "https://www.ncbi.nlm.nih.gov/gene/511829", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MNT2", "url": "https://www.orthodb.org/?gene=A0A3Q1MNT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MPP0", "url": "https://www.orthodb.org/?gene=A0A3Q1MPP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MYC5", "url": "https://www.orthodb.org/?gene=A0A3Q1MYC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NI60", "url": "https://www.orthodb.org/?gene=A0A3Q1NI60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12695:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12695:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46914", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46914", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46914:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46914:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04056", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04056", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07975", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07975", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17889", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17889", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22524", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MNT2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPP0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MYC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MYC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NI60", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NI60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NI60-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NI60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGY0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGY0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZE96", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZE96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZE96-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZE96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJU2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJU2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEJ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMFAVCARMCSVWTVMFLFMTLFIVVLAVFIRFQFLQLGLWINFEKMATQEKAPEERISQFDYALLPEMSAFLGVNALQFVKEIEEKEHRDREKMQKGFNSQMRSEAKRLKTFVTYNTFRSWTSQEMAEAGFYLTGTKSGIQCFCCSLILFGTSLQNTPMEHHKKFHPDCEFLLGKDVGNIAKYDVRVQKPENTLRRDDKARYQEEKARLESFKNWPFYAQGTSPRELSAAGFVFTGKHDTVQCFSCGGCLGNWEDDDDPWKEHAKWFPKCEFLQSKKSLEEITQYIQSYKGFVDVTGEHFLNSWVKRDLSVASVCCNGSNSSSFVNEELLLQSFKSWHPSYPVGAAALAKAGFFYTGKSDIVQCYSCGGYLHDWKEGDDPLEEHAKFFPNCQFLQSVKSSAEAIPDLQSHDELSELTETTNEGNLEESTAVSSIVPEVAQGEAQWFQEAESLSEHLRKVYTSAPFCHMSLLEISSCLATDQWLDCDLSFALKHITNPVQEPVVLPEVFANLNSVMCVEGEAGSGKTILLKKIAHLWASGRCPLLNRFRLVFCLSLGSTRPEQGLASVIRDQLLETKLSVTEMGLRNIIQQLKNQVLFLLDDYKEMCSVPQVIARMIQKKHLSRTCLVITVRTNRAKNIRRYLDTIIEIKAFPFYNTISILRKLFPGDLTRLRKLMVDFGMNQTWQGIQKTPLFVAAVRASWLQNRFHRSFDSVAVFESYMECLFLKHKTEADLLKATVSSCGDLALKGFFSSCFEFSDEDLIEAGIGEEEDLAMYLMSKFTAQRLRPVYQFLNPAFQEFLAGMRLTELLDSDRQEDQDLGLHYLKRINSTLMVIYPYANFLNCVSRHPSTKAGPKIVSHLLLLVDNKETLENISENDDYLKHHPEISEVMQFFRLIWQLSPQNYLSLASKHLLALAIRIAYQSNTVAACSPFILQFLRGRTLCLDVLKLQYFFDHPESLLLLRSIQVSINGNRLFKTDTPLERIFDKSQAPTIEQDYASAFELESEWKQSLDEKHEIIQNFQNMRLNAPPAINTGYWNLPSKQYKIPLLEVHVTNTHAVDQEMLRFLTEVFSAAQHIELHLNHSRGFIENIRPALEQFRASFTKCCISQCELSAIEQELLLTLTSLESLEVSETTHPQDQLFLSLDKFLCLKELSVNLQQDVFSAISEEFLNLHHMEKLLIQISSKCSPSKLVRLVQNSPNLQVFHLECNSFSDFESLVTALASRKKLEEIKFSGQFFQANPFVIVLPNFTSLKILKLGIQYIPDKETAEKFAYALGSLNNLEELILPTGDGIHQMAKLIIQQCQHLQCLQVLQFFKTLDDDSVVEIAKVAINGGFQKLKHLDFSMNHKITEEGYRNFFQTLDNLPSLQELTISRHFKECIKVQAATVKSLSQCVLRLPSLLRLNMLSWLLDAEDITLLTATIKKHPQSKHFILSWKWILPFSPIIQEPIS", "length": 1453, "header": "tr|E1BEJ9-1|E1BEJ9_BOVIN Isoform 1 of Ral transcription factor IIH, polypeptide 2, 44kDa OS=Bos taurus OX=9913 GN=NAIP PE=4 SV=4 CANONICAL=E1BEJ9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MNT2-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9/entry#A0A3Q1MNT2-1", "sequence": { "sequence": "MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIFSIYILGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKSLKAAKIRVSIIGLSAEVRVCTALARETGGTYHVILDESHYKELLTHHVSPPPASSNSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDSNTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEHNGERFCYACQGELKDQHVYVCSVCQNVFCVDCDVFVHDSLHCCPGCIHKIPVPSGI", "length": 384, "header": "tr|A0A3Q1MNT2-1|E1BEJ9_BOVIN Computationally mapped isoform of Ral transcription factor IIH, polypeptide 2, 44kDa OS=Bos taurus OX=9913 GN=NAIP PE=4 SV=1 CANONICAL=E1BEJ9-1" }, "locus": { "chromosome": "20", "start_pos": 10221071, "end_pos": 10202579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083800.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083800.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072953.1", "url": "https://www.ensembl.org/id/ENSBTAP00000072953.1" } ] } }, { "isoform_ac": "A0A3Q1MPP0-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9/entry#A0A3Q1MPP0-1", "sequence": { "sequence": "MTFLQYVRNKMDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKSLKAAKIRVSIIGLSAEVRVCTALARETGGTYHVILDESHYKELLTHHVSPPPASSNSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDSNTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEHNGERFCYACQGELKDQHVYVCSVCQNVFCVDCDVFVHDSLHCCPGCIHKIPVPSVHSANLVHLLSV", "length": 415, "header": "tr|A0A3Q1MPP0-1|E1BEJ9_BOVIN Computationally mapped isoform of Ral transcription factor IIH, polypeptide 2, 44kDa OS=Bos taurus OX=9913 GN=NAIP PE=4 SV=2 CANONICAL=E1BEJ9-1" }, "locus": { "chromosome": "20", "start_pos": 10221101, "end_pos": 10193839, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073943.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073943.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071624.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071624.2" } ] } }, { "isoform_ac": "A0A3Q1MYC5-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9/entry#A0A3Q1MYC5-1", "sequence": { "sequence": "MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKSLKAAKIRVSIIGLSAEVRVCTALARETGGTYHVILDESHYKELLTHHVSPPPASSNSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDSNTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEHNGERFCYACQGELKDQHVYVCSVCQNVFCVDCDVFVHDSLHCCPGCIHKIPVPSGKPFNITVIQDYALTTNAKEAEFEWFYEDLQDLLELTPKEDVLFIIGDWNAKVGSQEIPGITGTFGLGVQNEAEQRLTEFCQENALVIANTLFQQHKRRLYT", "length": 495, "header": "tr|A0A3Q1MYC5-1|E1BEJ9_BOVIN Computationally mapped isoform of Ral transcription factor IIH, polypeptide 2, 44kDa OS=Bos taurus OX=9913 GN=NAIP PE=4 SV=2 CANONICAL=E1BEJ9-1" }, "locus": { "chromosome": "20", "start_pos": 10221071, "end_pos": 10198871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073301.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073301.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061028.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061028.2" } ] } }, { "isoform_ac": "A0A3Q1NI60-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9/entry#A0A3Q1NI60-1", "sequence": { "sequence": "MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKLVFYIVYNL", "length": 166, "header": "tr|A0A3Q1NI60-1|E1BEJ9_BOVIN Computationally mapped isoform of Ral transcription factor IIH, polypeptide 2, 44kDa OS=Bos taurus OX=9913 GN=NAIP PE=4 SV=2 CANONICAL=E1BEJ9-1" }, "locus": { "chromosome": "20", "start_pos": 10221071, "end_pos": 10212432, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071833.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071833.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071687.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071687.2" } ] } }, { "isoform_ac": "A0AAA9TGY0-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9/entry#A0AAA9TGY0-1", "sequence": { "sequence": "MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGI", "length": 123, "header": "tr|A0AAA9TGY0-1|E1BEJ9_BOVIN Computationally mapped isoform of Ral transcription factor IIH, polypeptide 2, 44kDa OS=Bos taurus OX=9913 GN=NAIP PE=4 SV=1 CANONICAL=E1BEJ9-1" }, "locus": { "chromosome": "20", "start_pos": 10221071, "end_pos": 10202579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125792.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125792.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096123.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096123.1" } ] } }, { "isoform_ac": "A0AAF6ZE96-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9/entry#A0AAF6ZE96-1", "sequence": { "sequence": "MTFLQYVRNKMDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKSLKAAKIRVSIIGLSAEVRVCTALARETGGTYHVILDESHYKELLTHHVSPPPASSNSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDSNTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEHNGERFCYACQGELKDQHVYVCSVCQNVFCVDCDVFVHDSLHCCPGCIHKIPVPSGKRTGHWSHTDVDLNPFHDTAAALVLLVPRLKSMKPGEGLGDLPRKALGLAKLSTELCRPAGGIPGSLLPPCACLSPGRPGAMALPIGQA", "length": 493, "header": "tr|A0AAF6ZE96-1|E1BEJ9_BOVIN Computationally mapped isoform of Ral transcription factor IIH, polypeptide 2, 44kDa OS=Bos taurus OX=9913 GN=NAIP PE=4 SV=1 CANONICAL=E1BEJ9-1" }, "locus": { "chromosome": "20", "start_pos": 10221101, "end_pos": 10186821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000040362.5", "url": "https://www.ensembl.org/id/ENSBTAT00000040362.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040137.5", "url": "https://www.ensembl.org/id/ENSBTAP00000040137.5" } ] } }, { "isoform_ac": "A0ABI0NJU2-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9/entry#A0ABI0NJU2-1", "sequence": { "sequence": "MSMFAVCARMCSVWTVMFLFMTLFIVVLAVFIRFQFLQLGLWINFEKMATQEKAPEERISQFDYALLPEMSAFLGVNALQFVKEIEEKEHRDREKMQKGFNSQMRSEAKRLKTFVTYNTFRSWTSQEMAEAGFYLTGTKSGIQCFCCSLILFGTSLQNTPMEHHKKFHPDCEFLLGKDVGNIAKYDVRVQKPENTLRRDDKARYQEEKARLESFKNWPFYAQGTSPRELSAAGFVFTGKHDTVQCFSCGGCLGNWEDDDDPWKEHAKWFPKCEFLQSKKSLEEITQYIQSYKGFVDVTGEHFLNSWVKRDLSVASVCCNGSNSSSFVNEELLLQSFKSWHPSYPVGAAALAKAGFFYTGKSDIVQCYSCGGYLHDWKEGDDPLEEHAKFFPNCQFLQSVKSSAEAIPDLQSHDELSELTETTNEGNLEESTAVSSIVPEVAQGEAQWFQEAESLSEHLRKVYTSAPFCHMSLLEISSCLATDQWLDCDLSFALKHITNPVQEPVVLPEVFANLNSVMCVEGEAGSGKTILLKKIAHLWASGRCPLLNRFRLVFCLSLGSTRPEQGLASVIRDQLLETKLSVTEMGLRNIIQQLKNQVLFLLDDYKEMCSVPQVIARMIQKKHLSRTCLVITVRTNRAKNIRRYLDTIIEIKAFPFYNTISILRKLFPGDLTRLRKLMVDFGMNQTWQGIQKTPLFVAAVRASWLQNRFHRSFDSVAVFESYMECLFLKHKTEADLLKATVSSCGDLALKGFFSSCFEFSDEDLIEAGIGEEEDLAMYLMSKFTAQRLRPVYQFLNPAFQEFLAGMRLTELLDSDRQEDQDLGLHYLKRINSTLMVIYPYANFLNCVSRHPSTKAGPKIVSHLLLLVDNKETLENISENDDYLKHHPEISEVMQFFRLIWQLSPQNYLSLASKHLLALAIRIAYQSNTVAACSPFILQFLRGRTLCLDVLKLQYFFDHPESLLLLRSIQVSINGNRLFKTDTPLERIFDKSQAPTIEQDYASAFELESEWKQSLDEKHEIIQNFQNMRLNAPPAINTGYWNLPSKQYKIPLLEVHVTNTHAVDQEMLRFLTEVFSAAQHIELHLNHSRGFIENIRPALEQFRASFTKCCISQCELSAIEQELLLTLTSLESLEVSETTHPQVRLVQNSPNLQVFHLECNSFSDFESLVTALASRKKLEEIKFSGQFFQANPFVIVLPNFTSLKILKLGIQYIPDKETAEKFAYALGSLNNLEELILPTGDGIHQMAKLIIQQCQHLQCLQVLQFFKTLDDDSVVEIAKVAINGGFQKLKHLDFSMNHKITEEGYRNFFQTLDNLPSLQELTISRHFKECIKVQAATVKSLSQCVLRLPSLLRLNMLSWLLDAEDITLLTATIKKHPQSKHFILSWKWILPFSPIIQEPIS", "length": 1399, "header": "tr|A0ABI0NJU2-1|A0ABI0NJU2_BOVIN Computationally mapped isoform of Ral transcription factor IIH, polypeptide 2, 44kDa OS=Bos taurus OX=9913 GN=GTF2H2 PE=4 SV=1 CANONICAL=E1BEJ9-1" }, "locus": { "chromosome": "20", "start_pos": 10204146, "end_pos": 10147259, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140929.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140929.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104801.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104801.1" } ] } }, { "isoform_ac": "E1BEJ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9/entry#E1BEJ9-1", "sequence": { "sequence": "MSMFAVCARMCSVWTVMFLFMTLFIVVLAVFIRFQFLQLGLWINFEKMATQEKAPEERISQFDYALLPEMSAFLGVNALQFVKEIEEKEHRDREKMQKGFNSQMRSEAKRLKTFVTYNTFRSWTSQEMAEAGFYLTGTKSGIQCFCCSLILFGTSLQNTPMEHHKKFHPDCEFLLGKDVGNIAKYDVRVQKPENTLRRDDKARYQEEKARLESFKNWPFYAQGTSPRELSAAGFVFTGKHDTVQCFSCGGCLGNWEDDDDPWKEHAKWFPKCEFLQSKKSLEEITQYIQSYKGFVDVTGEHFLNSWVKRDLSVASVCCNGSNSSSFVNEELLLQSFKSWHPSYPVGAAALAKAGFFYTGKSDIVQCYSCGGYLHDWKEGDDPLEEHAKFFPNCQFLQSVKSSAEAIPDLQSHDELSELTETTNEGNLEESTAVSSIVPEVAQGEAQWFQEAESLSEHLRKVYTSAPFCHMSLLEISSCLATDQWLDCDLSFALKHITNPVQEPVVLPEVFANLNSVMCVEGEAGSGKTILLKKIAHLWASGRCPLLNRFRLVFCLSLGSTRPEQGLASVIRDQLLETKLSVTEMGLRNIIQQLKNQVLFLLDDYKEMCSVPQVIARMIQKKHLSRTCLVITVRTNRAKNIRRYLDTIIEIKAFPFYNTISILRKLFPGDLTRLRKLMVDFGMNQTWQGIQKTPLFVAAVRASWLQNRFHRSFDSVAVFESYMECLFLKHKTEADLLKATVSSCGDLALKGFFSSCFEFSDEDLIEAGIGEEEDLAMYLMSKFTAQRLRPVYQFLNPAFQEFLAGMRLTELLDSDRQEDQDLGLHYLKRINSTLMVIYPYANFLNCVSRHPSTKAGPKIVSHLLLLVDNKETLENISENDDYLKHHPEISEVMQFFRLIWQLSPQNYLSLASKHLLALAIRIAYQSNTVAACSPFILQFLRGRTLCLDVLKLQYFFDHPESLLLLRSIQVSINGNRLFKTDTPLERIFDKSQAPTIEQDYASAFELESEWKQSLDEKHEIIQNFQNMRLNAPPAINTGYWNLPSKQYKIPLLEVHVTNTHAVDQEMLRFLTEVFSAAQHIELHLNHSRGFIENIRPALEQFRASFTKCCISQCELSAIEQELLLTLTSLESLEVSETTHPQDQLFLSLDKFLCLKELSVNLQQDVFSAISEEFLNLHHMEKLLIQISSKCSPSKLVRLVQNSPNLQVFHLECNSFSDFESLVTALASRKKLEEIKFSGQFFQANPFVIVLPNFTSLKILKLGIQYIPDKETAEKFAYALGSLNNLEELILPTGDGIHQMAKLIIQQCQHLQCLQVLQFFKTLDDDSVVEIAKVAINGGFQKLKHLDFSMNHKITEEGYRNFFQTLDNLPSLQELTISRHFKECIKVQAATVKSLSQCVLRLPSLLRLNMLSWLLDAEDITLLTATIKKHPQSKHFILSWKWILPFSPIIQEPIS", "length": 1453, "header": "tr|E1BEJ9-1|E1BEJ9_BOVIN Isoform 1 of Ral transcription factor IIH, polypeptide 2, 44kDa OS=Bos taurus OX=9913 GN=NAIP PE=4 SV=4 CANONICAL=E1BEJ9-1" }, "locus": { "chromosome": "20", "start_pos": 10204146, "end_pos": 10147259, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004317.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004317.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004317.7", "url": "https://www.ensembl.org/id/ENSBTAP00000004317.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "detection of bacterium", "id": "GO:0016045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016045", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "pyroptotic inflammatory response", "id": "GO:0070269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070269", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase inhibitor activity involved in apoptotic process", "id": "GO:0043027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043027", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase inhibitor activity", "id": "GO:0004869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004869", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "transcription factor TFIIH core complex", "id": "GO:0000439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000439", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "transcription factor TFIIH holo complex", "id": "GO:0005675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005675", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" }, { "name": "IPAF inflammasome complex", "id": "GO:0072557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072557", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ9", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1084, "end_pos": 1086, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1251, "end_pos": 1253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 830, "end_pos": 832, "annotation": "n_glycosylation_sequon" }, { "start_pos": 874, "end_pos": 876, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEJ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1453, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEJ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEJ9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEJ9" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 515, "end_pos": 809, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1084, "end_pos": 1086 }, { "start_pos": 1251, "end_pos": 1253 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 683, "end_pos": 685 }, { "start_pos": 830, "end_pos": 832 }, { "start_pos": 874, "end_pos": 876 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEZ8-1", "uniprot_ac": "E1BEZ8", "uniprot_id": "E1BEZ8_BOVIN", "mass": { "chemical_mass": 134928.0, "monoisotopic_mass": 134928.0 }, "refseq": { "ac": "NP_001179428", "name": "tyrosine-protein phosphatase non-receptor type 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179428" }, "gene_names": [ { "name": "PTPN14", "type": "recommended", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] }, { "name": "PTPN14", "type": "synonym", "evidence": [ { "id": "NP_001179428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179428" } ] } ], "protein_names": [ { "name": "protein-tyrosine-phosphatase", "type": "recommended", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8/entry#names_and_taxonomy" } ] }, { "name": "tyrosine-protein phosphatase non-receptor type 14", "type": "synonym", "evidence": [ { "id": "NP_001179428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179428" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PTPN14", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8", "locus": { "chromosome": "16", "start_pos": 69223809, "end_pos": 69034895, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021553", "url": "https://www.ensembl.org/id/ENSBTAG00000021553" } ] } } ], "crossref": [ { "id": "E1BEZ8", "url": "https://alphafold.ebi.ac.uk/entry/E1BEZ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021553", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021553", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13188", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13188", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14599", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14599", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17191", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17191", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "518798", "url": "https://www.ncbi.nlm.nih.gov/gene/518798", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:518798", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518798", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKKCRQY", "url": "https://omabrowser.org/oma/group/FKKCRQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M9X9", "url": "https://www.orthodb.org/?gene=A0A3Q1M9X9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BEZ8", "url": "https://www.orthodb.org/?gene=E1BEZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45706:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45706:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179428", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179428", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M9X9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9X9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N575", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N575", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N575-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N575-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NDH9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NDH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEZ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSSVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCSLEQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQERKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNSVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELVNKEETALFHTEDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPMHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLSYLNGTVTNGGSVCSVHSVNSLSCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGVVHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTIPYGPQGGYGNKLVSPSDQLNPTNPTVPSKPGGPSAISHTVSTPELANMQLQGAHSYNAAHVLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGAVHKRHSLEAMSSMVRGMEAMTLKSLNIPMARRSTLREPGPPEEGPGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEEAPDPVPQIPVLREKVEYSTQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQACLPPAVARARLLRHGPAKAISVSRADQLAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLATLNGLSVARGSGREESRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGANVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTRNLRPPIVVHCSAGVGRTGVVILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI", "length": 1190, "header": "tr|E1BEZ8-1|E1BEZ8_BOVIN Isoform 1 of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPN14 PE=3 SV=3 CANONICAL=E1BEZ8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M9X9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8/entry#A0A3Q1M9X9-1", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSSVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCSLEQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQERKAHRTIMETVCTWAFSLWGFS", "length": 211, "header": "tr|A0A3Q1M9X9-1|E1BEZ8_BOVIN Computationally mapped isoform of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPN14 PE=3 SV=2 CANONICAL=E1BEZ8-1" }, "locus": { "chromosome": "16", "start_pos": 69186324, "end_pos": 69107098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071157.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071157.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067006.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067006.2" } ] } }, { "isoform_ac": "A0A3Q1N575-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8/entry#A0A3Q1N575-1", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSSVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCSLEQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQERKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNSVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELVNKEETALFHTEDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPMHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLSYLNGTVTNGGSVCSVHSVNSLSCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGVVHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTIPYGPQGGYGNKLVSPSDQLNPTNPTVPSKPGGPSAISHTVSTPELANMQLQGAHSYNAAHVLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGAVHKRHSLEAMSSMVRGMEAMTLKSLNIPMARRSTLREPGPPEEGPGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEEAPDPVPQIPVLREKVEYSTQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQACLPPAVARARLLRHGPAKAISVSRADQLAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLATLNGLSVARGSGREESRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTRNLRPPIVVHCSAGVGRTGVVILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI", "length": 1147, "header": "tr|A0A3Q1N575-1|E1BEZ8_BOVIN Computationally mapped isoform of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPN14 PE=3 SV=1 CANONICAL=E1BEZ8-1" }, "locus": { "chromosome": "16", "start_pos": 69223536, "end_pos": 69107098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070210.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070210.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065235.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065235.2" } ] } }, { "isoform_ac": "A0A3Q1NDH9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8/entry#A0A3Q1NDH9-1", "sequence": { "sequence": "MAPATSNKDKHRQRYQYYLQVKKDVLEGRLRCSLEQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQERKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNSVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELVNKEETALFHTEDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPMHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLSYLNGTVTNGGSVCSVHSVNSLSCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGVVHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTIPYGPQGGYGNKLVSPSDQLNPTNPTVPSKPGGPSAISHTVSTPELANMQLQGAHSYNAAHVLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGAVHKRHSLEAMSSMVRGMEAMTLKSLNIPMARRSTLREPGPPEEGPGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEEAPDPVPQIPVLREKVEYSTQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQACLPPAVARARLLRHGPAKAISVSRADQLAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLATLNGLSVARGSGREESRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGANVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTRNLRPPIVVHCSAGVGRTGVVILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI", "length": 1089, "header": "tr|A0A3Q1NDH9-1|E1BEZ8_BOVIN Computationally mapped isoform of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPN14 PE=3 SV=1 CANONICAL=E1BEZ8-1" }, "locus": { "chromosome": "16", "start_pos": 69223536, "end_pos": 69169696, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085748.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085748.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069540.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069540.2" } ] } }, { "isoform_ac": "E1BEZ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8/entry#E1BEZ8-1", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSSVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCSLEQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQERKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNSVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELVNKEETALFHTEDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPMHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLSYLNGTVTNGGSVCSVHSVNSLSCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGVVHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTIPYGPQGGYGNKLVSPSDQLNPTNPTVPSKPGGPSAISHTVSTPELANMQLQGAHSYNAAHVLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGAVHKRHSLEAMSSMVRGMEAMTLKSLNIPMARRSTLREPGPPEEGPGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEEAPDPVPQIPVLREKVEYSTQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQACLPPAVARARLLRHGPAKAISVSRADQLAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLATLNGLSVARGSGREESRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGANVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTRNLRPPIVVHCSAGVGRTGVVILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI", "length": 1190, "header": "tr|E1BEZ8-1|E1BEZ8_BOVIN Isoform 1 of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPN14 PE=3 SV=3 CANONICAL=E1BEZ8-1" }, "locus": { "chromosome": "16", "start_pos": 69223536, "end_pos": 69107098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028717.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028717.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028717.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028717.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:518798", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518798", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K2N0-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "Ptpn14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPSVSRLQQEATRYQYYLQVKKDVLEGRLRCSLEQVIRLAGLAVQADFGDYNQFDSQEFLREYVLFPMDLAMEEAALEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDSHGNSMHLGIFFMGIFVRNRIGRQAVIYRWNDIGTVTHSKAAILLELIDKEETALFHTDDIENAKYISRLFTTRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPMHVQCSEHYSETHTSQDSIFPGNEEALYCNSHNSLDLNYLNGTVTNGSVCSVHSINSLSCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSTIIVPSYRPTPDYETVMRQMKRGLLHADSQSRSLRNLNIINTHAYNQPEELVYSQPEMRERHPYTVPYAPQGGYGHKLVSPSDQVNPQNSAMPSKPGAGSISHTVSTPELANMQLQGAQHYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGGGGGAVNKRHSLEVMNSMVRGMEAMTLKSLNIPMARRNTLREQGPSEEAGGHDVHGLPQYHHKKTFSDATMLIHSSESEEEEEAPEAAPQIPELREKVEYSAQLQAALARIPSRPPPEYPGPRKSVSNGTLRQDQGTLLPAMARARVLRHGPAKALSVSRAEQLAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMTGLQAQKRPLMLAALNGLSVARVSGREDGRHDVTRVPMDERLRALKKKLEDGMVFTEYEQIPNKKANGIFSTATLPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGSEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGQERTVWHLQYTDWPHHGCPEDVQGFLSYLEEIQSVRRHTNSVLEGVKTRHPPIVVHCSAGVGRTGVVILSELMIYCLEHNEKVEVPTMLRFLREQRMFMIQTIAQYKFVYQVLVQFLQNSRLI", "length": 1189 }, "evidence": [ { "id": "E1BEZ8", "url": "https://omabrowser.org/oma/group/E1BEZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NVR5-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "PTPN14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKQLDKFANEPLLFFGVMFYVPSVSRLQQEVTRYQYYLQVKKDILDGRLRSSLEQGIRLAGLAVQADFGDYHQFESHDFLREYVLFPMDWTQDEAVLEELTQKVAQEHRTHSGITAAEAELMYINEVERLDGFGQEMFPVKDNHGNDIHLGIFFMGIFIKNRIGRTTVIYRWNDIGNIAHNKSSIVLELINKEENVLFHTDDLENAKYISRLFAARHKFYKQNKICTEQSSSPPPIRRRPTWSRSSLPRQHPFILPPMHVQCGDHYTETHNSQDSIFHGNEETFYCRSQTSLDRCPVDFSYLNGNGPNGSVCSAHSMNSLNRSQNFIQASPMSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGVIQMDSQSQSLRNLNIGNTHAYNQPEDLVYSQPEIRERHPYTVTYGPQGGGYNKPVTPSDQMNPNNAVQNKTAASAISHTVSTPELANMQLQSSQNYNTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVRQSLQEVSEPLLAVKHHAAVNKRHSLEVISNMVRGIEAMALKTLNAPLPRRNTLREQVQPEESVQMGHEVQQVPHYHHKKTFSDATMLIHSSESEEEEETTKSVSQIRALHENMKYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDHISASVAVARAKAMRPGPSKAISVSRTDQVAINGSSLGPSISEPDLTSVKERVKKEPVKERPVSEMFSIEDSIIEREIMMRNLEKQKMAGLEAQKRPLMLAALNGLSVARVPVPEDSQDEVAKVPMDERCKILKRKLEEGMVFTEYEQIPKKKADGIFTTAALPENTERNRIREVVPYEENRVELVPTKENNTGYINASHIKVTVGGEEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRSKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGDEKTVWHLQYTDWPDHGCPDEVQGFLSYLEEIQSVRRHTNSVLDSSNNCNPPIVVHCSAGVGRTGVVILTELMIGCLEHNEKVDVPVMLRHLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI", "length": 1191 }, "evidence": [ { "id": "E1BEZ8", "url": "https://omabrowser.org/oma/group/E1BEZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q15678-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 14", "gene_name": "PTPN14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCTLDQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELINKEETALFHTDDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPVHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLNYLNGTVTNGSVCSVHSVNSLNCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGILHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTVPYGPQGVYSNKLVSPSDQRNPKNNVVPSKPGASAISHTVSTPELANMQLQGSHNYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGTVNKRHSLEVMNSMVRGMEAMTLKSLHLPMARRNTLREQGPPEEGSGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEAPESVPQIPMLREKMEYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQASLPPAMARARVLRHGPAKAISMSRTDPPAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLAALNGLSVARVSGREENRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI", "length": 1187 }, "evidence": [ { "id": "E1BEZ8", "url": "https://omabrowser.org/oma/group/E1BEZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62130-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 14", "gene_name": "Ptpn14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSRLQQEATRYQYYLQVKKDVLEGRLRCSLEQVIRLAGLAVQADFGDYNQFDSQEFLREYVLFPMDLAMEEAALEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDSHGNSVHLGIFFMGIFVRNRVGRQAVIYRWNDIGSVTHSKAAILLELIDKEETALFHTDDIENAKYISRLFTTRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPMHVQCSEHYSETHTSQDSIFPGNEEALYCRSHNSLDLNYLNGTVTNGSVCSVHSVNSLSCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSTIIVPSYRPTPDYETVMRQMKRGLMHADSQSRSLRNLNIINTHAYNQPEELVYSQPEMRERHPYTVPYAHQGCYGHKLVSPSDQMNPQNCAMPIKPGASSISHTVSTPELANMQLQGAQHYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGGGGGTVNKRHSLEVMNSMVRGMEAMTLKSLNIPMARRNTLREQGPSEETGGHEVHGLPQYHHKKTFSDATMLIHSSESEEEEETLEAAPQVPVLREKVEYSAQLQAALARIPNRPPPEYPGPRKSVSNGALRQDQGTPLPAMARCRVLRHGPSKALSVSRAEQLAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMTGPQAQKRPLMLAALNGLSVARVSGREDGHHDATRVPIDERLRALKKKLEDGMVFTEYEQIPNKKANGVFSTATLPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGSEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGQERTVWHLQYTDWPHHGCPEDVQGFLSYLEEIQSVRRHTNSVLEGIRTRHPPIVVHCSAGVGRTGVVILSELMIYCLEHNEKVEVPTMLRFLREQRMFMIQTIAQYKFVYQVLVQFLQNSRLI", "length": 1189 }, "evidence": [ { "id": "E1BEZ8", "url": "https://omabrowser.org/oma/group/E1BEZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "pmid": "" }, { "name": "lymphangiogenesis", "id": "GO:0001946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001946", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "pmid": "" }, { "name": "regulation of protein export from nucleus", "id": "GO:0046825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046825", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "pmid": "" }, { "name": "positive regulation of hippo signaling", "id": "GO:0035332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035332", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ8", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 961, "end_pos": 963, "annotation": "n_glycosylation_sequon" }, { "start_pos": 967, "end_pos": 969, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1ME76-1", "F1MRH9-1", "A0AAF6DLF7-1", "A0AAA9S9Q3-1", "E1BFE2-1", "E1BL76-1", "G3MXS7-1", "A0A3Q1LUB1-1", "A0AAA9THG9-1", "F1N339-1", "F6RY99-1", "A0AAF6YUC8-1", "A0AAA9RTM1-1", "A0AAA9SMJ6-1", "A0A3Q1LZA9-1", "A7MBD1-1", "A5D7P0-1", "Q58DB6-1", "A0AAA9SEK4-1", "E1BDH9-1", "F1MGK4-1", "E1BIH4-1", "A0A3Q1M6K1-1", "E1BIU8-1", "A7MBJ4-1", "A6H730-1", "A0A3Q1MFX2-1", "A0AAA9U0H6-1", "A2VDT1-1", "E1BPU9-1", "P0C591-1", "P11064-1", "Q0IID7-1", "Q2KJ36-1", "Q2T9S4-1", "E1BPA0-1", "A0AAA9TAZ9-1", "Q5BIP9-1", "A0A3Q1M5K4-1", "F1MM08-1", "E1BJR7-1", "Q17QJ3-1", "Q17QM8-1", "F1MD22-1", "F1MI99-1", "F1MP34-1", "F1MGK5-1", "F1MEZ2-1", "F1MQM7-1", "E1BEZ8-1", "A0A3Q1M0B4-1", "A0AAA9S7W5-1", "A0A3Q1N8V6-1", "A0AAA9TFV5-1", "A0A3Q1MBB1-1", "F1MTZ3-1", "A0AAF6Z8C2-1", "F1MDF1-1", "A0AAA9T5N9-1", "E1BKT4-1", "A0A3Q1MH98-1", "F1N6L3-1", "F1MW70-1", "F1MXF2-1", "A0AAA9TWD1-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LUB1", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] } ] }, { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B4", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] } ] }, { "uniprot_ac": "A0A3Q1M5K4", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] } ] }, { "uniprot_ac": "A0A3Q1M6K1", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] } ] }, { "uniprot_ac": "A0A3Q1MBB1", "gene_name": "TNS2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] } ] }, { "uniprot_ac": "A0A3Q1MFX2", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1N8V6", "gene_name": "LOC101903026", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S7W5", "gene_name": "PTPRV", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] } ] }, { "uniprot_ac": "A0AAA9S9Q3", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] } ] }, { "uniprot_ac": "A0AAA9SEK4", "gene_name": "PTPRE", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] } ] }, { "uniprot_ac": "A0AAA9SMJ6", "gene_name": "PTPRH", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] } ] }, { "uniprot_ac": "A0AAA9T5N9", "gene_name": "", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] } ] }, { "uniprot_ac": "A0AAA9TAZ9", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] } ] }, { "uniprot_ac": "A0AAA9TFV5", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] } ] }, { "uniprot_ac": "A0AAA9THG9", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] } ] }, { "uniprot_ac": "A0AAA9TWD1", "gene_name": "PTPN20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YUC8", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] } ] }, { "uniprot_ac": "A0AAF6Z8C2", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] } ] }, { "uniprot_ac": "A2VDT1", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] } ] }, { "uniprot_ac": "A5D7P0", "gene_name": "CDC25C", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] } ] }, { "uniprot_ac": "A6H730", "gene_name": "ACP3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] } ] }, { "uniprot_ac": "A7MBD1", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] } ] }, { "uniprot_ac": "A7MBJ4", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] } ] }, { "uniprot_ac": "E1BDH9", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] } ] }, { "uniprot_ac": "E1BEZ8", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] } ] }, { "uniprot_ac": "E1BFE2", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] } ] }, { "uniprot_ac": "E1BIH4", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] } ] }, { "uniprot_ac": "E1BIU8", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] } ] }, { "uniprot_ac": "E1BJR7", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] } ] }, { "uniprot_ac": "E1BKT4", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] } ] }, { "uniprot_ac": "E1BL76", "gene_name": "CDC25B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] } ] }, { "uniprot_ac": "E1BPA0", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] } ] }, { "uniprot_ac": "E1BPU9", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] } ] }, { "uniprot_ac": "F1MD22", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] } ] }, { "uniprot_ac": "F1MDF1", "gene_name": "PTPN18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MGK4", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] } ] }, { "uniprot_ac": "F1MGK5", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MRH9", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] } ] }, { "uniprot_ac": "F1MTZ3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1MXF2", "gene_name": "MDP1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] } ] }, { "uniprot_ac": "F1N339", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] } ] }, { "uniprot_ac": "F1N6L3", "gene_name": "PTPN22", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6L3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6L3" } ] } ] }, { "uniprot_ac": "F6RY99", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F6RY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F6RY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ] } ] }, { "uniprot_ac": "G3MXS7", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ] } ] }, { "uniprot_ac": "P0C591", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] } ] }, { "uniprot_ac": "P11064", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] } ] }, { "uniprot_ac": "Q0IID7", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] } ] }, { "uniprot_ac": "Q17QJ3", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] } ] }, { "uniprot_ac": "Q17QM8", "gene_name": "DUSP14", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] } ] }, { "uniprot_ac": "Q2KJ36", "gene_name": "DUSP6", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] } ] }, { "uniprot_ac": "Q2T9S4", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] }, { "ec_number": "3.1.3.18", "activity": "2-phosphoglycolate + H2O = glycolate + phosphate.", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] }, { "ec_number": "3.1.3.18", "activity": "", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] } ] }, { "uniprot_ac": "Q58DB6", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q58DB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DB6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q58DB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DB6" } ] } ] }, { "uniprot_ac": "Q5BIP9", "gene_name": "DUSP18", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEZ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1190, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEZ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEZ8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.48", "ec_name": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48" }, { "id": "3.1.3.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.48" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 961, "end_pos": 963 }, { "start_pos": 967, "end_pos": 969 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFT7-1", "uniprot_ac": "E1BFT7", "uniprot_id": "E1BFT7_BOVIN", "mass": { "chemical_mass": 57117.0, "monoisotopic_mass": 57117.0 }, "refseq": { "ac": "XP_024840824", "name": "dynein axonemal assembly factor 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840824" }, "gene_names": [ { "name": "DNAAF8", "type": "recommended", "evidence": [ { "id": "E1BFT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFT7" } ] }, { "name": "C16orf71", "type": "synonym", "evidence": [ { "id": "XP_024840824", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840824" } ] }, { "name": "C25H16orf71", "type": "synonym", "evidence": [ { "id": "XP_024840824", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840824" } ] }, { "name": "DAAP1", "type": "synonym", "evidence": [ { "id": "XP_024840824", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840824" } ] }, { "name": "DNAAF8", "type": "synonym", "evidence": [ { "id": "XP_024840824", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840824" } ] } ], "protein_names": [ { "name": "Dynein axonemal assembly factor 8", "type": "recommended", "evidence": [ { "id": "E1BFT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFT7/entry#names_and_taxonomy" } ] }, { "name": "Dynein axonemal-associated protein 1", "type": "synonym", "evidence": [ { "id": "E1BFT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFT7/entry#names_and_taxonomy" } ] }, { "name": "dynein axonemal assembly factor 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024840824", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840824" } ] } ], "function": [ { "annotation": "In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1N7R3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7R3#function" }, { "database": "UniProtKB", "id": "ARBA00024177", "url": "https://www.uniprot.org/uniprotkb/ARBA00024177#function" }, { "database": "UniProtKB", "id": "F1MI79", "url": "https://www.uniprot.org/uniprotkb/F1MI79#function" }, { "database": "UniProtKB", "id": "E1BFT7", "url": "https://www.uniprot.org/uniprotkb/E1BFT7#function" }, { "database": "UniProtKB", "id": "A0ABI0P1N7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1N7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFT7", "url": "https://www.uniprot.org/uniprotkb/E1BFT7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DNAAF8", "url": "https://www.uniprot.org/uniprotkb/E1BFT7", "locus": {} } ], "crossref": [ { "id": "E1BFT7", "url": "https://alphafold.ebi.ac.uk/entry/E1BFT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006595", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006595", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618674", "url": "https://www.ncbi.nlm.nih.gov/gene/618674", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BFT7", "url": "https://www.orthodb.org/?gene=E1BFT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35977", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35977", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35977:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35977:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024840824", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840824", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N7R3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N7R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7R3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1N7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1N7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1N7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFT7", "url": "https://www.uniprot.org/uniprotkb/E1BFT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFT7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MI79", "url": "https://www.uniprot.org/uniprotkb/F1MI79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MI79-1", "url": "https://www.uniprot.org/uniprotkb/F1MI79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPDEDGRPSLPNPWDAILEAVKHQLPSLDSDSSASDCEDEELFIFQRNQTVLIPDLSEELADDPAGAWVTSSGSPPELAAVPVESAMEPWGEWNAWPRPQESAPLEGRAPSKSSSLLRMSAETPPRQDDDAGGTLNTSASQSPRQGPQGEATRSPQEAGLQTEPLGAASQAQEGSDAASRKALRRERRKMIEKDILHKVTWDGRNPACPDASRGKEKACDAVEVPSEGPPGCLPVLSLQELEEWDLDQVLLSLTGREEDRGDGAPGAAWWAAGRLQGQDHTEPSTQDRLMERLSLLCARQSRTAASAWRVPADTPREARPWESGSRWALLAPGPILPSGSFSQRLWCLDLKAGHLMCISLHLKNMIRCASRELGFQALAQDMQLKNPAEPPTIFTDLRPTKTSDQEPLESSSSYSSSSDSEEAEETAAQRDLQGPARLRDCTGKSRLLQQLRASREASAWPQLPAGKSPVSQKAQAPGDPAGSSPGVKQHVTLWAERGTQARPAGGRPSDSPGGLVPPWGQLQMPRV", "length": 529, "header": "tr|E1BFT7-1|E1BFT7_BOVIN Isoform 1 of Dynein axonemal assembly factor 8 OS=Bos taurus OX=9913 GN=DNAAF8 PE=4 SV=3 CANONICAL=E1BFT7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N7R3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFT7/entry#A0A3Q1N7R3-1", "sequence": { "sequence": "MASPDEDGRPSLPNPWDAILEAVKHQLPSLDSDSSASDCEDEELFIFQRNQTVLIPDLSEELADDPAGAWVTSSGSPPELAAVPVESAMEPWGEWNAWPRPQESAPLEGRAPSKSSSLLRMSAETPPRQDDDAGGTLNTSASQSPRQGPQGEATRSPQEAGLQTEPLGAASQAQEGSDAASRKALRRERRKMIEKDILHKVTWDGRNPACPDASRGKEKACDAVEVPSEGPPGCLPVLSLQELEEWDLDQVLLSLTGREEDRGDGAPGAAWWAAGRLQGQDHTEPSTQDRLMERLSLLCARQSRTAASAWRVPADTPREARPWESGSRWALLAPGPILPSGSFSQRLWCLDLKAGHLMCISLHLKNMIRCASRELGFQALAQDMQLKNPAEPPTIFTDLRPTKTSDQEPLERDCTGKSRLLQQLRASREASAWPQLPAGKSPVSQKAQAPGDPAGSSPGVKQHVTLWAERGTQARPAGGRPSDSPGGLVPPWGQLQMPRV", "length": 500, "header": "tr|A0A3Q1N7R3-1|E1BFT7_BOVIN Computationally mapped isoform of Dynein axonemal assembly factor 8 OS=Bos taurus OX=9913 GN=DNAAF8 PE=4 SV=2 CANONICAL=E1BFT7-1" }, "locus": { "chromosome": "25", "start_pos": 3830729, "end_pos": 3822318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074430.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074430.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066861.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066861.2" } ] } }, { "isoform_ac": "A0ABI0P1N7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFT7/entry#A0ABI0P1N7-1", "sequence": { "sequence": "MASPDEDGRPSLPNPWDAILEAVKHQLPSLDSDSSASDCEDEELFIFQRNQTVLIPDLSEELADDPAGAWVTSSGSPPELAAVPVESAMEPWGEWNAWPRPQESAPLEGRAPSKSSSLLRMSAETPPRQDDDAGGTLNTSASQSPRQGPQGEATRSPQEAGLQTEPLGAASQAQEGSDAASRKALRRERRKMIEKDILHKVTWDGRNPACPDASRGKEKACDAVEVPSEGPPGCLPVLSLQELEEWDLDQVLLSLTGREEDRGDGAPGAAWWAAGRLQGQDHTEPSTQDRLMERLSLLCARQSRTTCRAQPGYGTARERVGSSSSSGHLGRRPLGLSCPPARVLSVRRLRPLEIRPGPALG", "length": 361, "header": "tr|A0ABI0P1N7-1|A0ABI0P1N7_BOVIN Computationally mapped isoform of Dynein axonemal assembly factor 8 OS=Bos taurus OX=9913 GN=DNAAF8 PE=4 SV=1 CANONICAL=E1BFT7-1" }, "locus": { "chromosome": "25", "start_pos": 3830607, "end_pos": 3822318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148788.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148788.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104475.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104475.1" } ] } }, { "isoform_ac": "E1BFT7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFT7/entry#E1BFT7-1", "sequence": { "sequence": "MASPDEDGRPSLPNPWDAILEAVKHQLPSLDSDSSASDCEDEELFIFQRNQTVLIPDLSEELADDPAGAWVTSSGSPPELAAVPVESAMEPWGEWNAWPRPQESAPLEGRAPSKSSSLLRMSAETPPRQDDDAGGTLNTSASQSPRQGPQGEATRSPQEAGLQTEPLGAASQAQEGSDAASRKALRRERRKMIEKDILHKVTWDGRNPACPDASRGKEKACDAVEVPSEGPPGCLPVLSLQELEEWDLDQVLLSLTGREEDRGDGAPGAAWWAAGRLQGQDHTEPSTQDRLMERLSLLCARQSRTAASAWRVPADTPREARPWESGSRWALLAPGPILPSGSFSQRLWCLDLKAGHLMCISLHLKNMIRCASRELGFQALAQDMQLKNPAEPPTIFTDLRPTKTSDQEPLESSSSYSSSSDSEEAEETAAQRDLQGPARLRDCTGKSRLLQQLRASREASAWPQLPAGKSPVSQKAQAPGDPAGSSPGVKQHVTLWAERGTQARPAGGRPSDSPGGLVPPWGQLQMPRV", "length": 529, "header": "tr|E1BFT7-1|E1BFT7_BOVIN Isoform 1 of Dynein axonemal assembly factor 8 OS=Bos taurus OX=9913 GN=DNAAF8 PE=4 SV=3 CANONICAL=E1BFT7-1" }, "locus": { "chromosome": "25", "start_pos": 3830729, "end_pos": 3822318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008661.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008661.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008661.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008661.6" } ] } }, { "isoform_ac": "F1MI79-1", "url": "https://www.uniprot.org/uniprotkb/E1BFT7/entry#F1MI79-1", "sequence": { "sequence": "MASPDEDGRPSLPNPWDAILEAVKHQLPSLDSDSSASDCEDEELFIFQRNQTVLIPDLSEELADDPAGAWVTSSGSPPELAAVPVESAMEPWGEWNAWPRPQESAPLEGRAPSKSSSLLRMSAETPPRQDDDAGGTLNTSASQSPRQGPQGEATRSPQEAGLQTEPLGAASQAQEGSDAASRKALRRERRKMIEKDILHKVTWDGRNPACPDASRGKEKACDAVEVPSEGPPGCLPVLSLQELEEWDLDQVLLSLTGREEDRGDGAPGAAWWAAGRLQGQDHTEPSTQDRLMERLSLLCARQSRTAASAWRVPADTPREARPWESGSRWALLAPGPILPSGSFSQRLWCLDLKAGHLMCISLHLKNMIRDCTGKSRLLQQLRASREASAWPQLPAGKSPVSQKAQAPGDPAGSSPGVKQHVTLWAERGTQARPAGGRPSDSPGGLVPPWGQLQMPRV", "length": 457, "header": "tr|F1MI79-1|E1BFT7_BOVIN Computationally mapped isoform of Dynein axonemal assembly factor 8 OS=Bos taurus OX=9913 GN=DNAAF8 PE=4 SV=2 CANONICAL=E1BFT7-1" }, "locus": { "chromosome": "25", "start_pos": 3830729, "end_pos": 3822318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000037505.5", "url": "https://www.ensembl.org/id/ENSBTAT00000037505.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000037335.3", "url": "https://www.ensembl.org/id/ENSBTAP00000037335.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dynein complex binding", "id": "GO:0070840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070840", "evidence": [ { "database": "UniProtKB", "id": "E1BFT7", "url": "https://www.uniprot.org/uniprotkb/E1BFT7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "dynein axonemal particle", "id": "GO:0120293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120293", "evidence": [ { "database": "UniProtKB", "id": "E1BFT7", "url": "https://www.uniprot.org/uniprotkb/E1BFT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFT7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 529, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFT7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFT7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFF4-1", "uniprot_ac": "E1BFF4", "uniprot_id": "E1BFF4_BOVIN", "mass": { "chemical_mass": 113656.0, "monoisotopic_mass": 113656.0 }, "refseq": { "ac": "XP_010814932", "name": "kinesin-like protein KIF19 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814932" }, "gene_names": [ { "name": "KIF19", "type": "recommended", "evidence": [ { "id": "E1BFF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF4" } ] }, { "name": "KIF19", "type": "synonym", "evidence": [ { "id": "XP_010814932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814932" } ] } ], "protein_names": [ { "name": "Kinesin-like protein KIF19", "type": "recommended", "evidence": [ { "id": "E1BFF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF4/entry#names_and_taxonomy" } ] }, { "name": "kinesin-like protein KIF19 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010814932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814932" } ] } ], "function": [ { "annotation": "Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips.", "evidence": [ { "database": "UniProtKB", "id": "E1BFF4", "url": "https://www.uniprot.org/uniprotkb/E1BFF4#function" }, { "database": "UniProtKB", "id": "ARBA00055376", "url": "https://www.uniprot.org/uniprotkb/ARBA00055376#function" }, { "database": "UniProtKB", "id": "A0A3Q1MQT9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQT9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFF4", "url": "https://www.uniprot.org/uniprotkb/E1BFF4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KIF19", "url": "https://www.uniprot.org/uniprotkb/E1BFF4", "locus": { "chromosome": "19", "start_pos": 57053263, "end_pos": 57110955, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004617", "url": "https://www.ensembl.org/id/ENSBTAG00000004617" } ] } } ], "crossref": [ { "id": "E1BFF4", "url": "https://alphafold.ebi.ac.uk/entry/E1BFF4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004617", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004617", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01370", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01370", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538109", "url": "https://www.ncbi.nlm.nih.gov/gene/538109", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538109", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538109", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GEQKQLC", "url": "https://omabrowser.org/oma/group/GEQKQLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFF4", "url": "https://www.orthodb.org/?gene=E1BFF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47968", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47968", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47968:SF69", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47968:SF69", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47968:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47968:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010814932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814932", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM82", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM82-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAX1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQT9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NGC7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NGC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFF4", "url": "https://www.uniprot.org/uniprotkb/E1BFF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFF4-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKDSGDSKDQQLMVALRIRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEPGIYVRTLNDLFRAIEETSDDMEYEVSMSYLEIYNEMIRDLLNPSLGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMRGNRQRTQEPTAANQTSSRSHAVLQVAVRQRSRVRDVLQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGTNKYVNYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYASRAKSIKTRVKRNLLSVSYHIAQYTNIIADLRGEIQRLKRKIEERGGRSLDRAQLGRGDIRHIQAEVQLHSGQGEQAAMEHLREQLISTFQEQMDTRRRLLELENRGMELETDTSHHLLTIASWKHEKSRRALKWREERRKESFTKDDTRKDSDTGDNQPDIEEPAEVVSARESIATLMTEQKKLRKQKLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRRLEQRLSLCEEIIRAQRQLIQDCNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALQDSALPKISPPGTVPTPEESDLESVKMPNSESPHQHGSFLPLLGTESEANHPFKTSSRAWQAKGFCLPTPPPIRGGNLVTQEATTQVGLNGQINSSPESIENLSEIPLSHKGRKETAADTKSIAGKAARHHLQALGAKGRQLLAPTIKQSSLSLHLKGQTDDVRPPGPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVECHGNGPCPPLQGQEKSPRNKREESLEAKRKRRSQAFEVTGQGIPTQLPAHLALQPTQLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTTPVAAPSNPGDVSERVARMPRLPYGTSTQNKNGHFGHN", "length": 1014, "header": "tr|E1BFF4-1|E1BFF4_BOVIN Isoform 1 of Kinesin-like protein KIF19 OS=Bos taurus OX=9913 GN=KIF19 PE=3 SV=3 CANONICAL=E1BFF4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LM82-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF4/entry#A0A3Q1LM82-1", "sequence": { "sequence": "MKDSGDSKDQQLMVALRIRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEPGIYVRTLNDLFRAIEETSDDMEYEVSMSYLEIYNEMIRDLLNPSLGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMRGNRQRTQEPTAANQTSSRSHAVLQVAVRQRSRVRDVLQEVRQGRLFMIDLAGSERASQDSLGGNSRTVMIAHISPASSAFEESRNTLTYASRAKSIKTRVKRNLLSVSYHIAQYTNIIADLRGEIQRLKRKIEERGGRSLDRAQLGRGDIRHIQAEVQLHSGQGEQAAMEHLREQLISTFQEQMDTRRRLLELENRGMELETDTSHHLLTIASWKHEKSRRALKWREERRKESFTKDDTRKDSDTGDNQPDIEEPAEVVSARESIATLMTEQKKLRKQKLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRRLEQRLSLCEEIIRAQRQLIQDCNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALQDSALPKISPPGTVPTPEESDLESVKMPNSESPHQHGSFLPLLGTESEANHPFKTSSRAWQAKGFCLPTPPPIRGGNLVTQEATTQVGLNGQINSSPESIENLSEIPLSHKGRKETAADTKSIAGKAARHHLQALGAKGRQLLAPTIKQSSLSLHLKGQTDDVRPPGPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVECHGNGPCPPLQGQEKSPRNKREESLEAKRKRRSQAFEVTGQGIPTQLPAHLALQPTQLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTTPVAAPSNPGDVSERVARMPRLPYGTSTQNKNGHFGHN", "length": 965, "header": "tr|A0A3Q1LM82-1|E1BFF4_BOVIN Computationally mapped isoform of Kinesin-like protein KIF19 OS=Bos taurus OX=9913 GN=KIF19 PE=3 SV=1 CANONICAL=E1BFF4-1" }, "locus": { "chromosome": "19", "start_pos": 57110703, "end_pos": 57083285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077742.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077742.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057762.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057762.2" } ] } }, { "isoform_ac": "A0A3Q1MAX1-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF4/entry#A0A3Q1MAX1-1", "sequence": { "sequence": "MKDSGDSKDQQLMVALRIRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEPGIYVRTLNDLFRAIEETSDDMEYEVSMSYLEIMQLLMRGNRQRTQEPTAANQTSSRSHAVLQVAVRQRSRVRDVLQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGTNKYVNYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYASRAKSIKTRVKRNLLSVSYHIAQYTNIIADLRGEIQRLKRKIEERGGRSLDRAQLGRGDIRHIQAEVQLHSGQGEQAAMEHLREQLISTFQEQMDTRRRLLELENRGMELETDTSHHLLTIASWKHEKSRRALKWREERRKESFTKDDTRKDSDTGDNQPDIEEPAEVVSARESIATLMTEQKKLRKQKLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRRLEQRLSLCEEIIRAQRQLIQDCNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALQDSALPKISPPGTVPTPEESDLESVKMPNSESPHQHGSFLPLLGTESEANHPFKTSSRAWQAKGFCLPTPPPIRGGNLVTQEATTQVGLNGQINSSPESIENLSEIPLSHKGRKETAADTKSIAGKAARHHLQALGAKGRQLLAPTIKQSSLSLHLKGQTDDVRPPGPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVECHGNGPCPPLQGQEKSPRNKREESLEAKRKRRSQAFEVTGQGIPTQLPAHLALQPTQLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTTPVAAPSNPGDVSERVARMPRLPYGTSTQNKNGHFGHN", "length": 972, "header": "tr|A0A3Q1MAX1-1|E1BFF4_BOVIN Computationally mapped isoform of Kinesin-like protein KIF19 OS=Bos taurus OX=9913 GN=KIF19 PE=3 SV=2 CANONICAL=E1BFF4-1" }, "locus": { "chromosome": "19", "start_pos": 57110703, "end_pos": 57083285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071896.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071896.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065775.3", "url": "https://www.ensembl.org/id/ENSBTAP00000065775.3" } ] } }, { "isoform_ac": "A0A3Q1MQT9-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF4/entry#A0A3Q1MQT9-1", "sequence": { "sequence": "MKDSGDSKDQQLMVALRIRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEPGIYVRTLNDLFRAIEETSDDMEYEVSMSYLEIYNEMIRDLLNPSLGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMRGNRQRTQEPTAANQTSSRSHAVLQVAVRQRSRVRDVLQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGTNKYVNYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYASRAKSIKTRVKRNLLSVSYHIAQYTNIIADLRGEIQRLKRKIEERGGRSLDRAQLGRGDIRHIQAEVQLHSGQGEQAAMEHLREQLISTFQEQMDTRRRLLELENRGMELETDTSHHLLTIASWKHEKSRRALKWREERRKESFTKDDTRKDSDTGDNQPDIEEPAEVVSARESIATLMTEQKKLRKQKLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRRLEQRLSLCEEIIRAQRQLIQDCNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALDSALPKISPPGTVPTPEESDLESVKMPNSESPHQHGSFLPLLGTESEANHPFKTSSRAWQAKGFCLPTPPPIRGGNLVTQEATTQVGLNGQINSSPESIENLSEIPLSHKGRKETAADTKSIAGKAARHHLQALGAKGRQLLAPTIKQSSLSLHLKGQTDDVRPPGPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVECHGNGPCPPLQGQEKSPRNKREESLEAKRKRRSQAFEVTGQGLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTTPVAAPSNPGDVSERVARMPRLPYGTSTQNKNGHFGHN", "length": 998, "header": "tr|A0A3Q1MQT9-1|E1BFF4_BOVIN Computationally mapped isoform of Kinesin-like protein KIF19 OS=Bos taurus OX=9913 GN=KIF19 PE=3 SV=1 CANONICAL=E1BFF4-1" }, "locus": { "chromosome": "19", "start_pos": 57110703, "end_pos": 57053266, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084163.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084163.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056773.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056773.2" } ] } }, { "isoform_ac": "A0A3Q1NGC7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF4/entry#A0A3Q1NGC7-1", "sequence": { "sequence": "MKDSGDSKDQQLMVALRIRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEPGIYVRTLNDLFRAIEETSDDMEYEVSMSYLEIYNEMIRDLLNPSLGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMRGNRQRTQEPTAANQTSSRSHAVLQVAVRQRSRVRDVLQEVRQGRLFMIDLAGSERASQVKRNLLSVSYHIAQYTNIIADLRGEIQRLKRKIEERGGRSLDRAQLGRGDIRHIQAEVQLHSGQGEQAAMEHLREQLISTFQEQMDTRRRLLELENRGMELETDTSHHLLTIASWKHEKSRRALKWREERRKESFTKDDTRKDSDTGDNQPDIEEPAEVVSARESIATLMTEQKKLRKQKLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRRLEQRLSLCEEIIRAQRQLIQDCNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALQDSALPKISPPGTVPTPEESDLESVKMPNSESPHQHGSFLPLLGTESEANHPFKTSSRAWQAKGFCLPTPPPIRGGNLVTQEATTQVGLNGQINSSPESIENLSEIPLSHKGRKETAADTKSIAGKAARHHLQALGAKGRQLLAPTIKQSSLSLHLKGQTDDVRPPGPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVECHGNGPCPPLQGQEKSPRNKREESLEAKRKRRSQAFEVTGQGIPTQLPAHLALQPTQLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTTPVAAPSNPGDVSERVARMPRLPYGTSTQNKNGHFGHN", "length": 924, "header": "tr|A0A3Q1NGC7-1|E1BFF4_BOVIN Computationally mapped isoform of Kinesin-like protein KIF19 OS=Bos taurus OX=9913 GN=KIF19 PE=3 SV=2 CANONICAL=E1BFF4-1" }, "locus": { "chromosome": "19", "start_pos": 57110703, "end_pos": 57083285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083188.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083188.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070856.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070856.2" } ] } }, { "isoform_ac": "E1BFF4-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF4/entry#E1BFF4-1", "sequence": { "sequence": "MKDSGDSKDQQLMVALRIRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEPGIYVRTLNDLFRAIEETSDDMEYEVSMSYLEIYNEMIRDLLNPSLGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMRGNRQRTQEPTAANQTSSRSHAVLQVAVRQRSRVRDVLQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGTNKYVNYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYASRAKSIKTRVKRNLLSVSYHIAQYTNIIADLRGEIQRLKRKIEERGGRSLDRAQLGRGDIRHIQAEVQLHSGQGEQAAMEHLREQLISTFQEQMDTRRRLLELENRGMELETDTSHHLLTIASWKHEKSRRALKWREERRKESFTKDDTRKDSDTGDNQPDIEEPAEVVSARESIATLMTEQKKLRKQKLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRRLEQRLSLCEEIIRAQRQLIQDCNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALQDSALPKISPPGTVPTPEESDLESVKMPNSESPHQHGSFLPLLGTESEANHPFKTSSRAWQAKGFCLPTPPPIRGGNLVTQEATTQVGLNGQINSSPESIENLSEIPLSHKGRKETAADTKSIAGKAARHHLQALGAKGRQLLAPTIKQSSLSLHLKGQTDDVRPPGPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVECHGNGPCPPLQGQEKSPRNKREESLEAKRKRRSQAFEVTGQGIPTQLPAHLALQPTQLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTTPVAAPSNPGDVSERVARMPRLPYGTSTQNKNGHFGHN", "length": 1014, "header": "tr|E1BFF4-1|E1BFF4_BOVIN Isoform 1 of Kinesin-like protein KIF19 OS=Bos taurus OX=9913 GN=KIF19 PE=3 SV=3 CANONICAL=E1BFF4-1" }, "locus": { "chromosome": "19", "start_pos": 57110703, "end_pos": 57083285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006057.8", "url": "https://www.ensembl.org/id/ENSBTAT00000006057.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006057.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006057.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 675, "start_aa": "Thr", "end_pos": 675, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr675", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:538109", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538109", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A976-1", "protein_name": "Kinesin-like protein", "gene_name": "Kif19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDSGDSKDQQLMVALRVRPISVSELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEPGIYVRTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPALGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVAVRQRNRVKNILQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGGNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASTAFEESRNTLTYAGRAKNIRTRVKQNLLNVSYHIAQYTSIIADLRGEIQRLKCKIDQQAGRGQARGKLDRGDIRHIQAEVQLHSGQEEQAEMGQLREQLISAFHEQMDVRRRLLELENQAMEVQIDTSRHLLTIASWEHEKSRRALKWREERRKESYTKEDSEKDSDTGDEPDNLEPPEVASARENIAALVGEQKKLRKEKLALEQRCRELRARGRRLEETLPRRIGSEEQREVLSLLCRVHELEVENTEMQSHALLRDSALRHRREAVRRLEQHRSLCDEIIQGQRQIIDDYNLEIPRHLEELYEVYLRELEEGSLERATIMDRVASRALQDSSLPKITPAGTTLTPDSDLESVKTLSSEAQCPQNNTLPPLGTDSDSYHMFKASPRAWQVKSSSVPTPPPIQVGSLVTQEAPPQDSLGSQINSSPDSSENLSEILLSHKERKEILTRTKCISVKAAQRRSRALGTEGRHLLAPATERSSLSLHSLSEADDVRPPGPLACKRPPSPTLQHAISEDNLSSSTGEGPARAVGPRGDGSGPWVRGQKKCLSKKREESLEAKRRKRRSRSFEVTGQGLSRSKTHLLGPRPSEGVSDRRMPACGRPSPGVRHLGKVSLPLAKVKFPPNQNTGSGNPSPLLVPSNQAGVSRRATRGPNLPHGSSTFGKDGRLQHN", "length": 997 }, "evidence": [ { "id": "E1BFF4", "url": "https://omabrowser.org/oma/group/E1BFF4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LEH8-1", "protein_name": "Kinesin-like protein KIF19", "gene_name": "KIF19", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKDSGDSKDQQLMVALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEPGIYVRTLNDLFRAIEETSDDMEYEVSMSYLEIYNEMIRDLLNPALGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVAVRQRSRVRNILQEVRQGRLFMVDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKSGNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNLLSVSYHIAQYTSIIADLRGEIQRLKRKIDEQGGRGRARFQPERGNIRPIPAEVPLQSGQGEQAELGQLREQLISAFQEQMDVRRRLLELENHAMEVQIDTSRHLLTIAGWEHEKSRRALKWREEQRKESYTKDDSEKDSDTGDDQPDILEPPEVASARESIAALMGEQKKLRKQKVTLEQRCRELRARGRRLEETLPRRIGSEEQREVLSLLCRVHELEVENTEMQSHALLRDGALRHRREAVRRLEQHRSLCDEIIQGQRQIIDDYNLAVPQHLEELYEVYLRELEEGSLERATIMDRVASRALQDSSLPQISPAGTLLTPESEPESMKTLSTEAQRLHSSFLPPLSTESAANYTFKASPRVWQGKSSSVPTPPPIRIGNLVTQEAPTQDSLVSLSSRINSSPDSSENLSEIPLSHKERKEILTSTKCISVKAARRRTRALGTEGRHLLAPSVERSSLSLNSLSEADDARRPGPLACKRPPSPTLQHAASEDNLSSSTGDTPSRAVERRGNGPGPWLCGQKKSLGKKREESLEAKRRKRRSRSFEVMGQGLSRPKTHLLGPRPVESISDHRMPVCGHPAPGIRQPGRVMLPMAKVKLPPSQNTGPGDSSPLAVPSNPAGVSRRATHGPRLPHGTSTHGKNGRLRHN", "length": 1001 }, "evidence": [ { "id": "E1BFF4", "url": "https://omabrowser.org/oma/group/E1BFF4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2TAC6-1", "protein_name": "Kinesin-like protein KIF19", "gene_name": "KIF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKDSGDSKDQQLMVALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDQEPGIYVQTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSLGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGSNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNLLNVSYHIAQYTSIIADLRGEIQRLKRKIDEQTGRGQARGRQDRGDIRHIQAEVQLHSGQGEKAGMGQLREQLASAFQEQMDVRRRLLELENRAMEVQIDTSRHLLTIAGWKHEKSRRALKWREEQRKECYAKDDSEKDSDTGDDQPDILEPPEVAAARESIAALVDEQKQLRKQKLALEQRCRELRARGRRLEETLPRRIGSEEQREVLSLLCRVHELEVENTEMQSHALLRDGALRHRHEAVRRLEQHRSLCDEIIQGQRQIIDDYNLAVPQRLEELYEVYLRELEEGSLEQATIMDQVASRALQDSSLPKITPAGTSLTPDSDLESVKTLSSDAQHLQNSALPPLSTESEGHHVFKAGTGAWQAKSSSVPTPPPIQLGSLVTQEAPAQDSLGSWINSSPDSSENLSEIPLSHKERKEILTGTKCIWVKAARRRSRALGTEGRHLLAPATERSSLSLHSLSEGDDARPPGPLACKRPPSPTLQHAASEDNLSSSTGEAPSRAVGHHGDGPRPWLRGQKKSLGKKREESLEAKRRKRRSRSFEVTGQGLSHPKTHLLGPHQAERISDHRMPVCRHPAPGIRHLGKVTLPLAKVKLPPSQNTGPGDSSPLAVPPNPGGGSRRATRGPRLPHGTSTHGKDGCSRHN", "length": 998 }, "evidence": [ { "id": "E1BFF4", "url": "https://omabrowser.org/oma/group/E1BFF4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99PT9-1", "protein_name": "Kinesin-like protein KIF19", "gene_name": "Kif19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKDSGDSKDQQLMVALRVRPISVAELEEGATLIAHKMDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEPGIYVRTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPALGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVAVRQRSRVKNILQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGSNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASTAFEESRNTLTYAGRAKNIRTRVKQNLLNVSYHIAQYTSIIADLRGEIQRLKCKIDQQAGRGQARGKLDRGDIRHIQAEVQLHSGQEGPAEMGQLREQLISAFHEQMDVRRRLLELENQAMEVQIDTSRHLLTIAGWEHEKSRRALKWREERRKESYTKEDSEKDSDTGDEPDNLEPPEVASARENIAALVGEQKKLRKEKLALEQRCRELRARGRRLEETLPRRIGSEEQREVLSLLCRVHELEVENTEMQSHALLRDSALRHRREAVRRLEQHRSLCDEIIQGQRQIIDDYNLEVPRHLEELYEVYLRELEEGSLERATIMDRVASRALQDSSLPKITPAGATLTPDSDLESVKTLSSEAQRPQNNTLPPLGTDSESYHVFKASPRAWQVKSSSVPTPPPIQVGSLVTQEAPPQDSLGSQINSSPESSENLSEILLSHKERKEILTRTKCISVKAAQRRSRALGTEGRHLLAPATERSSLSLHSLSEADDARPPGQLACKRPPSPTLQHAISEDNLSSSTGEGPSRAVGPRGDGTGSWVRGQKKCLSKKREESLEAKRRKRRSRSFEVTGQGLSRPKTHLLGPRPSEGLSDRRMPACGRPSPGVRHLGKVSLPLAKVKFPPNQNTGSGNPSPLLVAPNQAGVSRRATRGPSLPHGSSTFGKDGRLQHN", "length": 997 }, "evidence": [ { "id": "E1BFF4", "url": "https://omabrowser.org/oma/group/E1BFF4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BFF4", "url": "https://www.uniprot.org/uniprotkb/E1BFF4" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BFF4", "url": "https://www.uniprot.org/uniprotkb/E1BFF4" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "E1BFF4", "url": "https://www.uniprot.org/uniprotkb/E1BFF4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "E1BFF4", "url": "https://www.uniprot.org/uniprotkb/E1BFF4" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "E1BFF4", "url": "https://www.uniprot.org/uniprotkb/E1BFF4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "E1BFF4", "url": "https://www.uniprot.org/uniprotkb/E1BFF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 761, "end_pos": 763, "annotation": "n_glycosylation_sequon" }, { "start_pos": 933, "end_pos": 935, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFF4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1014, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFF4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFF4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF4" }, { "id": "PS50067", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinesin motor", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 346, "start_aa": "Gln", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 675 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 753, "end_pos": 755 }, { "start_pos": 761, "end_pos": 763 }, { "start_pos": 933, "end_pos": 935 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIG0-1", "uniprot_ac": "E1BIG0", "uniprot_id": "E1BIG0_BOVIN", "mass": { "chemical_mass": 33357.0, "monoisotopic_mass": 33357.0 }, "refseq": { "ac": "NP_001039870", "name": "tRNA N(3)-cytidine methyltransferase METTL6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039870" }, "gene_names": [ { "name": "METTL6", "type": "recommended", "evidence": [ { "id": "E1BIG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ] }, { "name": "METTL6", "type": "synonym", "evidence": [ { "id": "NP_001039870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039870" } ] } ], "protein_names": [ { "name": "tRNA N(3)-cytidine methyltransferase", "type": "recommended", "evidence": [ { "id": "E1BIG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIG0/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.-", "type": "synonym", "evidence": [ { "id": "E1BIG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIG0/entry#names_and_taxonomy" } ] }, { "name": "methyltransferase like 6", "type": "synonym", "evidence": [ { "id": "NP_001039870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039870" } ] }, { "name": "tRNA N(3)-cytidine methyltransferase METTL6", "type": "synonym", "evidence": [ { "id": "NP_001039870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039870" } ] } ], "function": [ { "annotation": "S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Ser), including tRNA(Ser)(UGA) and tRNA(Ser)(GCU). Interaction with SARS1/SerRS is required for N(3)-methylcytidine methylation.", "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0#function" }, { "database": "UniProtKB", "id": "ARBA00058280", "url": "https://www.uniprot.org/uniprotkb/ARBA00058280#function" }, { "database": "UniProtKB", "id": "A0A3Q1NGQ1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGQ1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "METTL6", "url": "https://www.uniprot.org/uniprotkb/E1BIG0", "locus": { "chromosome": "1", "start_pos": 152434382, "end_pos": 152450925, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000023375", "url": "https://www.ensembl.org/id/ENSBTAG00000023375" } ] } } ], "crossref": [ { "id": "E1BIG0", "url": "https://alphafold.ebi.ac.uk/entry/E1BIG0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000023375", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000023375", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "535332", "url": "https://www.ncbi.nlm.nih.gov/gene/535332", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:535332", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535332", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAQRNWD", "url": "https://omabrowser.org/oma/group/DAQRNWD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NGQ1", "url": "https://www.orthodb.org/?gene=A0A3Q1NGQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BIG0", "url": "https://www.orthodb.org/?gene=E1BIG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22809:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22809:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08242", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08242", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001039870", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039870", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "50956", "url": "https://www.rhea-db.org/rhea/50956", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1NGQ1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NGQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1T9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1T9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIG0-1", "url": "https://www.uniprot.org/uniprotkb/E1BIG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALQRRGLQTRILSSEEEEKLKRDQALVSDFKQQKLEKEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCREFEDQKLTILEAGCGVGNCLFPLLEEDPDIFAYACDFSPRAVEYVKQNPLYDTERCKVFQCDLTKDDLLEHVPPESVDVVTLIFVLSAVHPDKMHLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKAGSKLAENFYVRQDGTRSYFFTDEFLARLFLDTGYEEEVNEYVFRETVNKKEGLCVPRVFLQSKFRKSQKNPIPVTPDLGHES", "length": 284, "header": "tr|E1BIG0-1|E1BIG0_BOVIN Isoform 1 of tRNA N(3)-cytidine methyltransferase OS=Bos taurus OX=9913 GN=METTL6 PE=3 SV=1 CANONICAL=E1BIG0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NGQ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BIG0/entry#A0A3Q1NGQ1-1", "sequence": { "sequence": "MAALQRRGLQTRILSSEEEEKLKRDQALVSDFKQQKLEKEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCREFEDQKLTILEAGCGVGNCLFPLLEEDPDIFAYACDFSPRAVEYVKQNPLYDTERCKVFQCDLTKDDLLEHVPPESVDVVTLIFVLSAVHPDKMHLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKAGSKLAENFYVRQDGTRSYFFTDGCHHQMFFFSAPCYLTALRHVRIEFLARLFLDTGYEEEVNEYVFRETVNKKEGLCVPRVFLQSKFRKSQKNPIPVTPDLGHES", "length": 307, "header": "tr|A0A3Q1NGQ1-1|E1BIG0_BOVIN Computationally mapped isoform of tRNA N(3)-cytidine methyltransferase OS=Bos taurus OX=9913 GN=METTL6 PE=3 SV=1 CANONICAL=E1BIG0-1" }, "locus": { "chromosome": "1", "start_pos": 152449786, "end_pos": 152434705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079401.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079401.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071014.1", "url": "https://www.ensembl.org/id/ENSBTAP00000071014.1" } ] } }, { "isoform_ac": "A0AAA9T1T9-1", "url": "https://www.uniprot.org/uniprotkb/E1BIG0/entry#A0AAA9T1T9-1", "sequence": { "sequence": "MAALQRRGLQTRILSSEEEEKLKRDQALVSDFKQQKLEKEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCREQNPLYDTERCKVFQCDLTKDDLLEHVPPESVDVVTLIFVLSAVHPDKMHLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKAGSKLAENFYVRQDGTRSYFFTDEFLARLFLDTGYEEEVNEYVFRETVNKKEGLCVPRVFLQSKFRKSQKNPIPVTPDLGHES", "length": 239, "header": "tr|A0AAA9T1T9-1|E1BIG0_BOVIN Computationally mapped isoform of tRNA N(3)-cytidine methyltransferase OS=Bos taurus OX=9913 GN=METTL6 PE=3 SV=1 CANONICAL=E1BIG0-1" }, "locus": { "chromosome": "1", "start_pos": 152449786, "end_pos": 152434705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094329.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094329.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092769.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092769.1" } ] } }, { "isoform_ac": "E1BIG0-1", "url": "https://www.uniprot.org/uniprotkb/E1BIG0/entry#E1BIG0-1", "sequence": { "sequence": "MAALQRRGLQTRILSSEEEEKLKRDQALVSDFKQQKLEKEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCREFEDQKLTILEAGCGVGNCLFPLLEEDPDIFAYACDFSPRAVEYVKQNPLYDTERCKVFQCDLTKDDLLEHVPPESVDVVTLIFVLSAVHPDKMHLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKAGSKLAENFYVRQDGTRSYFFTDEFLARLFLDTGYEEEVNEYVFRETVNKKEGLCVPRVFLQSKFRKSQKNPIPVTPDLGHES", "length": 284, "header": "tr|E1BIG0-1|E1BIG0_BOVIN Isoform 1 of tRNA N(3)-cytidine methyltransferase OS=Bos taurus OX=9913 GN=METTL6 PE=3 SV=1 CANONICAL=E1BIG0-1" }, "locus": { "chromosome": "1", "start_pos": 152449786, "end_pos": 152434705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031819.4", "url": "https://www.ensembl.org/id/ENSBTAT00000031819.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000031765.3", "url": "https://www.ensembl.org/id/ENSBTAP00000031765.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:535332", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535332", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0RMK9-1", "protein_name": "tRNA N(3)-cytidine methyltransferase", "gene_name": "METTL6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASLQRKGLQARVLSSEEEEKLKRDQALVSDFKQQKLEKEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAVEYVKQNPLYDTERCKAFQCDLTKDDLLEHVPPESVDVVTLIFVLSAVHPDKMRLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKAGSKLAENFYVRQDGTRSYFFTDEFLARLFLDTGYEEQVNEYVFRATVNKKEGLCVQRVFLQSKFRKSPKNPAPMTLGLDHES", "length": 284 }, "evidence": [ { "id": "E1BIG0", "url": "https://omabrowser.org/oma/group/E1BIG0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YYD4-1", "protein_name": "tRNA N(3)-cytidine methyltransferase", "gene_name": "METTL6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "GHGGNAPREPPPRRRGQPGPSRAALRGCGLSAQGSWRKAVRSDCCEAGRDCLSTLTTSTEDGAFQTKGHNTRILSPEEAERLANDRVLVSDFKQLKLEKEAQKNWDLFYKRNSTNFFKDRHWTTREFQELKACREFADQKLTILEAGCGVGNCLFPLLEEDLNIFAYACDFSPRAVEYVKKNSLYSTERCKVFQCDLTKDDLLENIPADSVDVVTLIFVLSAIHPDKMHLVLKNIYKVLKPGKCVLFRDYGLYDHAMLRFKSGSKLGENFYVRQDGTRSYFFTTEFLSQLFRAEGYEEVVNEYVHRETVNRKEDLRVPRVFLQSKFQKPFSKT", "length": 333 }, "evidence": [ { "id": "E1BIG0", "url": "https://omabrowser.org/oma/group/E1BIG0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A1ZAY5-1", "protein_name": "tRNA N(3)-methylcytidine methyltransferase", "gene_name": "Dmel\\CG34195", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEPLEPDVITTQAKELSAVERQKLDEQNKRGLVPEYKANKLEIDAQRNWDIFYKRNETRFFKDRHWTTREFQELLDQEEFHEKRTLFEVGCGVGNLVFPLLEEQTSEEGCFSNSRFFFYACDFSPRAVEFVRSNPLYDPSQISAFQCDITTQQVHDHIPPSSVDICTLIFVLSAIHPQKFKDVVQNLGKLLKPGGLLLFRDYGLYDMAQLRFKPGNKIAENLYVRQDGTRSYFFSEEEVSKLFQENGFEVITNAYVHRRTLNLKEGVDVPRIFLQGKFRRKNL", "length": 283 }, "evidence": [ { "id": "E1BIG0", "url": "https://omabrowser.org/oma/group/E1BIG0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6AXU8-1", "protein_name": "tRNA N(3)-cytidine methyltransferase METTL6", "gene_name": "Mettl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSLQRKGPQTRILSTGEEEKLKRDQALVSAFKQQKLEKEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCREYEGQKLTLLEAGCGVGNCLFPLLEEDSNIFAYACDFSPRAVDYVKQHPLYNAERCKVFQCDLTRDDLLDHIPPESVDAVTLIFVLSAVHPEKMHLVLLNVYKVLKPGRSVLFRDYGLNDHAMLRFKAGSKLGENFYVRQDGTRSYFFTDEFLAKLFVDAGYEEVVNEYVFRETVNKKEGLCVPRVFLQSKFRKPPKDPAPTTDSASLLRKEF", "length": 287 }, "evidence": [ { "id": "E1BIG0", "url": "https://omabrowser.org/oma/group/E1BIG0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86I59-1", "protein_name": "tRNA N(3)-methylcytidine methyltransferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTSSNNNNNNNNNNNKYFYNIIDDELGYARLYGYIDREKQKTLSPALIEKYEKEADKYWDKFYRKNNSNFFKDRHWLVREFPEFLKNSDKEVSKENQLLAFEIGCGVGNTTIPLLELNDNLHFVSFDFSEHAVKLLNQSVSENPKINGRCKGFVYNAIDGPSGLPDYIENDQFDLIIIIFVLSAMDPKTIPSVVDMCYRTLKPGGKVLIRDYAIDDMAQSRFDNNNPDFDNNEEEDLDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTINGGSKNKLGDNFHVRFDGTRAYYFSLEVMESLYKEKGFKTEQNHYIFRQVLNRKDNYLMDRKFIQSKFIK", "length": 341 }, "evidence": [ { "id": "E1BIG0", "url": "https://omabrowser.org/oma/group/E1BIG0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BVH9-1", "protein_name": "tRNA N(3)-cytidine methyltransferase METTL6", "gene_name": "Mettl6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFQRKGLQARILSTEEEEKLKRDQALVSAFKQQKLEKEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCREYEGQKLTLLEAGCGVGNCLFPLLEEDLNLFAYACDFSPRAVDYVKQHPLYNAERCKVFQCDLTRDDLLDHVPPESVDAVTLIFVLSAVHPEKMRLVLLNVYKVLKPGRSVLFRDYGLNDHAMLRFKAGSKLGENFYVRQDGTRSYFFTDEFLAQLFVDAGYEEVVNEYVFRETVNKKEGLCVPRVFLQSKFRKPPKDPAPTSDSASL", "length": 282 }, "evidence": [ { "id": "E1BIG0", "url": "https://omabrowser.org/oma/group/E1BIG0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TCB7-1", "protein_name": "tRNA N(3)-cytidine methyltransferase METTL6", "gene_name": "METTL6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASLQRKGLQARILTSEEEEKLKRDQTLVSDFKQQKLEQEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVVNEYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS", "length": 284 }, "evidence": [ { "id": "E1BIG0", "url": "https://omabrowser.org/oma/group/E1BIG0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ], "pmid": "" }, { "name": "tRNA (cytidine-3-)-methyltransferase activity", "id": "GO:0052735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052735", "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ], "pmid": "" }, { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "tRNA C3-cytosine methylation", "id": "GO:0106217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106217", "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ], "pmid": "" }, { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "E1BIG0", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "50956", "name": "", "equation": "cytidine(32) in tRNA(Ser) + S-adenosyl-L-methionine = N(3)-methylcytidine(32) in tRNA(Ser) + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BIG0-1" ], "evidence": [ { "id": "50956", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50956" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BIG0", "gene_name": "METTL6", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "E1BIG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIG0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 284, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIG0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIG0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIG0" }, { "id": "PF08242", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08242" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase type 12", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 182, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHI0-1", "uniprot_ac": "E1BHI0", "uniprot_id": "E1BHI0_BOVIN", "mass": { "chemical_mass": 69990.0, "monoisotopic_mass": 69990.0 }, "refseq": { "ac": "XP_010815601", "name": "WD repeat-containing protein 76 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815601" }, "gene_names": [ { "name": "WDR76", "type": "recommended", "evidence": [ { "id": "E1BHI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHI0" } ] }, { "name": "WDR76", "type": "synonym", "evidence": [ { "id": "XP_010815601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815601" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 76", "type": 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515302", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515302", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DPNTLYW", "url": "https://omabrowser.org/oma/group/DPNTLYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHI0", "url": "https://www.orthodb.org/?gene=E1BHI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14773", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14773", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14773:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14773:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010815601", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815601", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK59", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK59-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0Z6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NH12", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NH12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NH12-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NH12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQ34", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQ34-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPV9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPV9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHI0", "url": "https://www.uniprot.org/uniprotkb/E1BHI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHI0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZF6", "url": "https://www.uniprot.org/uniprotkb/G3MZF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZF6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGSRAEAEQKGGSRQRLQVNEYKENQNIADTSLRPVQTTVLGVTAKVCLVPFSLSNYNTGQLKRPKSLLDKNSNSEVTCKKSKKAEIKKSCRRLLTPKMEATSSKEESTLQKSSLDVHAESNKWQYKSPSDTVVLSPDTESSQEGDSDEDTTPGLDDFSELSPYERKRLKNISENANFFASLQLSESAARFREMIKKRQPPESKRKKPKKKENETGCRRSMRLLKVDPSGVPLPAAPIQTVLEVDENPLIPPGPLEMTPENQDDDNALFKGFLQTWAEMSKTRSKNTEKELSSIKSYKVHLNGMVISEDTVCKVTRGSISSMAIHPSEMRTLVAAGAKSGQVGLWDLTHQPKEDGVYLFQPHSQPVSCLYFSPANPAHLLSLSYDGTLRCGDFSRAVFEEVYRDETRSFSSFDFLTEDASTLIVGHWDGSMSLVDRRTPGTSCEKLIKTSLSKIRTVHVHPVQRQYLITAGLRDIHVYDARCLNLSRNQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCKLRIFDSSCISSKIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCIVVGSMAQPRRVEVFHETGKWVHSFLGGECLASVCSINAMHPTRYILAGGNSSGRVHVFMN", "length": 627, "header": "tr|E1BHI0-1|E1BHI0_BOVIN Isoform 1 of WD repeat-containing protein 76 OS=Bos taurus OX=9913 GN=WDR76 PE=3 SV=2 CANONICAL=E1BHI0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LK59-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI0/entry#A0A3Q1LK59-1", "sequence": { "sequence": "MSGSRAEAEQKGGSRQRLQVNEYKENQNIADTSLRPVQTTVLGVTAKVCLVPFSLSNYNTGQLKRPKSLLDKNSNSEVTCKKSKKAEIKKSCRRLLTPKMEATSSKEESTLQKSSLDVHAESNKWQYKSPSDTVVLSPDTESSQEGDSDEDTTPGLSAARFREMIKKRQPPESKRKKPKKKENETGCRRSMRLLKVDPSGVPLPAAPIQTVLEVDENPLIPPGPLEMTPENQDDDNALFKGFLQTWAEMSKTRSKNTEKELSSIKSYKVHLNGMVISEDTVCKVTRGSISSMAIHPSEMRTLVAAGAKSGQVGLWDLTHQPKEDGVYLFQPHSQPVSCLYFSPANPAHLLSLSYDGTLRCGDFSRAVFEEVYRDETRSFSSFDFLTEDASTLIVGHWDGSMSLVDRRTPGTSCEKLIKTSLSKIRTVHVHPVQRQYLITAGLRDIHVYDARCLNLSRNQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCKLRIFDSSCISSKIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCIVVGSMAQPRRVEVFHETGKWVHSFLGGECLASVCSINAMHPTRYILAGGNSSGRVHVFMN", "length": 596, "header": "tr|A0A3Q1LK59-1|E1BHI0_BOVIN Computationally mapped isoform of WD repeat-containing protein 76 OS=Bos taurus OX=9913 GN=WDR76 PE=3 SV=3 CANONICAL=E1BHI0-1" }, "locus": { "chromosome": "21", "start_pos": 55487546, "end_pos": 55436811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087007.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087007.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056983.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056983.3" } ] } }, { "isoform_ac": "A0A3Q1M0Z6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI0/entry#A0A3Q1M0Z6-1", "sequence": { "sequence": "MSGSRAEAEQKGGSRQRLQVNEYKENQNIADTSLRPVQTTVLGVTAKVCLVPFSLSNYNTGQLKRPKSLLDKNSNSEVTCKKSKKAEIKKSCRRLLTPKMEATSSKEESTLQKSSLDVHAESNKWQYKSPSDTVVLSPDTESSQEGDSDEDTTPGLDDFSELSPYERKRLKNISENANFFASLQLSESAARFREMIKKRQPPESKRKKPKKKENETGCRRSMRLLKVDPSGVPLPAAPIQTVLEVDENPLIPPGPLEMTPENQDDDNALFKGFLQTWAEMSKTRSKNTEKELSSIKSYKVHLNGMVISEDTVCKVTRGSISSMAIHPSEMRTLVAAGAKSGQVGLWDLTHQPKEDGVYLFQPHSQPVSCLYFSPANPAHLLSLSYDGTLRCGDFSRAVFEEVYRDETRSFSSFDFLTEDASTLIVGHWDGSMSLVDRRTPGTSCEKLIKTSLSKIRTVHVHPVQRQYLITAGLRIFDSSCISSKIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCIVVGSMAQPRRVEVFHETGKWVHSFLGGECLASVCSINAMHPTRYILAGGNSSGRVHVFMN", "length": 576, "header": "tr|A0A3Q1M0Z6-1|E1BHI0_BOVIN Computationally mapped isoform of WD repeat-containing protein 76 OS=Bos taurus OX=9913 GN=WDR76 PE=3 SV=1 CANONICAL=E1BHI0-1" }, "locus": { "chromosome": "21", "start_pos": 55487546, "end_pos": 55436811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072770.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072770.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066917.1", "url": "https://www.ensembl.org/id/ENSBTAP00000066917.1" } ] } }, { "isoform_ac": "A0A3Q1NH12-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI0/entry#A0A3Q1NH12-1", "sequence": { "sequence": "MLSRAHIARRGGFSLGEAQVFFKVRYRHQQRQKPPGSKVNEYKENQNIADTSLRPVQTTVLGVTAKVCLVPFSLSNYNTGQLKRPKSLLDKNSNSEVTCKKSKKAEIKKSCRRLLTPKMEATSSKEESTLQKSSLDVHAESNKWQYKSPSDTVVLSPDTESSQEGDSDEDTTPGLDDFSELSPYERKRLKNISENANFFASLQLSESAARFREMIKKRQPPESKRKKPKKKENETGCRRSMRLLKVDPSGVPLPAAPIQTVLEVDENPLIPPGPLEMTPENQDDDNALFKGFLQTWAEMSKTRSKNTEKELSSIKSYKVHLNGMVISEDTVCKVTRGSISSMAIHPSEMRTLVAAGAKSGQVGLWDLTHQPKEDGVYLFQPHSQPVSCLYFSPANPAHLLSLSYDGTLRCGDFSRAVFEEVYRDETRSFSSFDFLTEDASTLIVGHWDGSMSLVDRRTPGTSCEKLIKTSLSKIRTVHVHPVQRQYLITAGLRDIHVYDARCLNLSRNQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCKLRIFDSSCISSKIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCIVVGSMAQPRRVEVFHETGKWVHSFLGGECLASVCSINAMHPTRYILAGGNSSGRVHVFMN", "length": 646, "header": "tr|A0A3Q1NH12-1|E1BHI0_BOVIN Computationally mapped isoform of WD repeat-containing protein 76 OS=Bos taurus OX=9913 GN=WDR76 PE=3 SV=1 CANONICAL=E1BHI0-1" }, "locus": { "chromosome": "21", "start_pos": 55487546, "end_pos": 55436028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078876.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078876.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071172.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071172.2" } ] } }, { "isoform_ac": "A0AAA9SQ34-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI0/entry#A0AAA9SQ34-1", "sequence": { "sequence": "MSGSRAEAEQKGGSRQRLQVNEYKENQNIADTSLRPVQTTVLGVTAKMEATSSKEESTLQKSSLDVHAESNKWQYKSPSDTVVLSPDTESSQEGDSDEDTTPGLDDFSELSPYERKRLKNISENANFFASLQLSESAARFREMIKKRQPPESKRKKPKKKENETGCRRSMRLLKVDPSGVPLPAAPIQTVLEVDENPLIPPGPLEMTPENQDDDNALFKGFLQTWAEMSKTRSKNTEKELSSIKSYKVHLNGMVISEDTVCKVTRGSISSMAIHPSEMRTLVAAGAKSGQVGLWDLTHQPKEDGVYLFQPHSQPVSCLYFSPANPAHLLSLSYDGTLRCGDFSRAVFEEVYRDETRSFSSFDFLTEDASTLIVGHWDGSMSLVDRRTPGTSCEKLIKTSLSKIRTVHVHPVQRQYLITAGLRDIHVYDARCLNLSRNQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCKLRIFDSSCISSKIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCIVVGSMAQPRRVEVFHETGKWVHSFLGGECLASVCSINAMHPTRYILAGGNSSGRVHVFMN", "length": 575, "header": "tr|A0AAA9SQ34-1|E1BHI0_BOVIN Computationally mapped isoform of WD repeat-containing protein 76 OS=Bos taurus OX=9913 GN=WDR76 PE=3 SV=1 CANONICAL=E1BHI0-1" }, "locus": { "chromosome": "21", "start_pos": 55487546, "end_pos": 55436811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100277.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100277.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088432.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088432.1" } ] } }, { "isoform_ac": "A0ABI0NPV9-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI0/entry#A0ABI0NPV9-1", "sequence": { "sequence": "MSGSRAEAEQKGGSRQRLQVNEYKENQNIADTSLRPVQTTVLGVTAKVCLVPFSLSNYNTGQLKRPKSLLDKNSNSEVTCKKSKKAEIKKSCRRLLTPKMEATSSKEESTLQKSSLDVHAESNKWQYKSPSDTVVLSPDTESSQEGDSDEDTTPGLDDFSELSPYERKRLKNISENANFFASLQLSESAARFREMIKKRQPPESKRKKPKKKENETGCRRSMRLLKVDPSGVPLPAAPIQTVLEVDENPLIPPGPLEMTPENQDDDNALFKGFLQTWAEMSKTRSKNTEKELSSIKSYKVHLNGMVISEDTVCKVTRGSISSMAIHPSEMRTLVAAGAKSGQVGLWDLTHQPKEDGVYLFQPHSQPVSCLYFSPANPAHLLSLSYDGTLRCGDFSRAVFEEVYRDETRSFSSFDFLTEDASTLIVGHWDGSMSLVDRRTPGTSCEKLIKTSLSKIRTVHVHPVQRQYLITAGLRIFDSSCISSKIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCIVVGSMAQPRRVEVFHETGKWVHSFLGGECLASVCSINAMHPTRYILAGEAVAT", "length": 569, "header": "tr|A0ABI0NPV9-1|A0ABI0NPV9_BOVIN Computationally mapped isoform of WD repeat-containing protein 76 OS=Bos taurus OX=9913 GN=WDR76 PE=3 SV=1 CANONICAL=E1BHI0-1" }, "locus": { "chromosome": "21", "start_pos": 55488621, "end_pos": 55436811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152778.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152778.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105176.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105176.1" } ] } }, { "isoform_ac": "E1BHI0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI0/entry#E1BHI0-1", "sequence": { "sequence": "MSGSRAEAEQKGGSRQRLQVNEYKENQNIADTSLRPVQTTVLGVTAKVCLVPFSLSNYNTGQLKRPKSLLDKNSNSEVTCKKSKKAEIKKSCRRLLTPKMEATSSKEESTLQKSSLDVHAESNKWQYKSPSDTVVLSPDTESSQEGDSDEDTTPGLDDFSELSPYERKRLKNISENANFFASLQLSESAARFREMIKKRQPPESKRKKPKKKENETGCRRSMRLLKVDPSGVPLPAAPIQTVLEVDENPLIPPGPLEMTPENQDDDNALFKGFLQTWAEMSKTRSKNTEKELSSIKSYKVHLNGMVISEDTVCKVTRGSISSMAIHPSEMRTLVAAGAKSGQVGLWDLTHQPKEDGVYLFQPHSQPVSCLYFSPANPAHLLSLSYDGTLRCGDFSRAVFEEVYRDETRSFSSFDFLTEDASTLIVGHWDGSMSLVDRRTPGTSCEKLIKTSLSKIRTVHVHPVQRQYLITAGLRDIHVYDARCLNLSRNQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCKLRIFDSSCISSKIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCIVVGSMAQPRRVEVFHETGKWVHSFLGGECLASVCSINAMHPTRYILAGGNSSGRVHVFMN", "length": 627, "header": "tr|E1BHI0-1|E1BHI0_BOVIN Isoform 1 of WD repeat-containing protein 76 OS=Bos taurus OX=9913 GN=WDR76 PE=3 SV=2 CANONICAL=E1BHI0-1" }, "locus": { "chromosome": "21", "start_pos": 55487546, "end_pos": 55436811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022879.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022879.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022879.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022879.5" } ] } }, { "isoform_ac": "G3MZF6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI0/entry#G3MZF6-1", "sequence": { "sequence": "MFVCESAHIARRGGFSLGEAQVFFKVRYRHQQRQKPPGSKVNEYKENQNIADTSLRPVQTTVLGVTAKVCLVPFSLSNYNTGQLKRPKSLLDKNSNSEVTCKKSKKAEIKKSCRRLLTPKMEATSSKEESTLQKSSLDVHAESNKWQYKSPSDTVVLSPDTESSQEGDSDEDTTPGLDDFSELSPYERKRLKNISENANFFASLQLSESAARFREMIKKRQPPESKRKKPKKKENETGCRRSMRLLKVDPSGVPLPAAPIQTVLEVDENPLIPPGPLEMTPENQDDDNALFKGFLQTWAEMSKTRSKNTEKELSSIKSYKVHLNGMVISEDTVCKVTRGSISSMAIHPSEMRTLVAAGAKSGQVGLWDLTHQPKEDGVYLFQPHSQPVSCLYFSPANPAHLLSLSYDGTLRCGDFSRAVFEEVYRDETRSFSSFDFLTEDASTLIVGHWDGSMSLVDRRTPGTSCEKLIKTSLSKIRTVHVHPVQRQYLITAGLRDIHVYDARCLNLSRNQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCKLRIFDSSCISSKIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCIVVGSMAQPRRVEVFHETGKWVHSFLGGECLASVCSINAMHPTRYILAGGNSSGRVHVFMN", "length": 648, "header": "tr|G3MZF6-1|E1BHI0_BOVIN Computationally mapped isoform of WD repeat-containing protein 76 OS=Bos taurus OX=9913 GN=WDR76 PE=3 SV=3 CANONICAL=E1BHI0-1" }, "locus": { "chromosome": "21", "start_pos": 55487546, "end_pos": 55435105, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064513.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064513.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054953.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054953.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515302", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515302", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9Q1Q9-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "wdr76", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDTDKSDLSLETMKLLQERTPPQNPGMDGSVLRTSRRIKEKQNQRKKQNLPPKCLTFRSEVKSTKRVVKRRISGSEKEKEVKRSKADPDHESLPQGYREGLSEYQLERLENIRKNQAFLNSLNLTEISEALRPKQKPTQKGLKKEKTQVEMLPVRKSLRLQNKGPQSTTATEFTFPTTYELEKEAKPPGPIPLDPINLDEDATLPDDLLDVWNEVPLEQSTGTPDLKSYERMLKKLSIDDSRVVKVVKERICCAAFHPSSNLLMAAGDKYGHLGLWRPDAEWGDDGVVCFEPHSRAITALAFTSQPCNLITASYDGSARSMDLEKAVFDEVYRSSSSLKSFDFLSSDCSTLLFGEWNGDVAVVDRRTGNLCESLHAMTAAPLRGVHVHPVQQHYFLVAESSFVNIYDLRHLKKRNSPAVCELYGHNRSTSSAFFSPLTGSRVLTTCMDDCIRVFDSSQIAGRIPALTSIRHNMQTGRWLSRLCAVWDPKHQECFVIGTMDRPRKIKVYHESGRLLHTLQNTEHLTTVCSVTAFHPSRNALLGGNASGRLHIYTD", "length": 554 }, "evidence": [ { "id": "E1BHI0", "url": "https://omabrowser.org/oma/group/E1BHI0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A9J7G8W8-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "Wdr76", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGCNAEAEEKAGSKQCPQVQVNEYKENGNCAYTSLRPIQTTTSGKTAKAYCLSPFSLSNSKRARFKLSTSPFESHPNNAVACKKTGRKKTCRKGVTSKMKAVSSKAESLLLKPPVDAYTDSELRHSSTAESVTLSVDMGSSDEDSAPGLGDFSELSPYERKRLKNIKENANFFASLELSESAARLRGMIKKRQPPESKRKRPKKKENEIGCRRSMRLLKVDPLGVSLPAAPTQPMLEEEEENPLLPPGPLEMIPENQDDSNELFRASLKTWADMSKTSNERTKEGLSSIKSYKANLSGMVISEATVRKVTRGAISSVALHPSEVRTLVAAGAKSGQIGLWDLTRQCEDGVYVFYPHSQPVSCLYFSPTNPAHLLSLSYDGTLRCGDFSSAVFEEVYRNEGNSPSSFDFLAKDASTLLVGHWDGHLSLVDRRTPGTSHEKFFNSSMGKIRTVHVHPVSRQYFITAGLRDVHVYDVRCLNSRGSQPMISLAEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSSLSSQIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCFIVGSMAHPRRVEVFHETGESVRSLSGDCLVSVCSLSVMHPTRYVLAGGNSSGRLHVFMSQESF", "length": 624 }, "evidence": [ { "id": "E1BHI0", "url": "https://omabrowser.org/oma/group/E1BHI0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A6PWY4-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "Wdr76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGSKAESEEKAGSKQCPLVQVNEYKENEHIAYTSLRPIQITTLRKTAKVYLYPFSLSNSKLGLLKLSKSPVVNNSSKSVVHKKKDRKKTRRKVLTSKMKALSSKADSLLLKSSVDAYTESTRLGPKRTSDSATLSVDAESSDEDSAPGLDDFSGLSPYERKRLRNIRENANFFASLQLAESAARLRGMIKKRESPESKRKRPKKKENEIGCRRSMRLLKVDPLGVSLPASPTQPTLVEEEENPLLPPGPLEMIPENQDDSSELLKASLKTWAEMSQTSNEKTKKGLSSIKSYKANLSGMVISEATVRKVTKGAISSVALHPSEVRTLVAAGAKSGQIGLWDLTQQSEDAMYVFYAHSRYVSCLSFSPTNPAHLLSLSYDGTLRCGDFSSAVFEEVYRNEGNSPSSFDFLNDSSSLLVGHWDGHLSLVDRRTPGTSYEKFFNSSLEKIRTVHVHPLSRQYFVTAGLRDVHVYDARFLKSRGSQPLISLTEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSSISSQLPLLSTIRHNTVTGRWLTRFQAVWDPKQEDCFIVGSMDHPRRVEVFHESGKNVHSLWGECLVSVCSLSAVHPTRYILAGGNSSGKLHVFMHQET", "length": 622 }, "evidence": [ { "id": "E1BHI0", "url": "https://omabrowser.org/oma/group/E1BHI0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZJT1-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "Wdr76", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGFIAVAEEKAGSKQCPQVQVNEYKENENIAYTSLRPIQITTRRKAAKVYLYPFSLSNPKLGLFKLSKSPVENKSSSEMVQKKTDQKKTCRRVLTSKMKALSSKAESCLLKPALDSHTESSELEHKSISDPVTPSVDMESSDEDSAPGPDDFSGLSPYERKRMKNIRENANFFASLQLAESAARLRGMIKKNQPPESKRKRPKKKENEVGCRRSMRLLKVDPLGVSLPASLTQPTLVEEETPMIPPGPLEMIPENQDDCSELFKASLKTWAEMSQTSNEKTKKGLSSIKSYKASLSGMVVSEATIRKVTKGAISSVAIHPSGVRTLVAAGSKSGQVGLWDLTQQSEDGAYAFCPHSQPVSCLSFSPTNPAHLLSLSYDGTVRCGDFSTAVFEEVYRNERNSLSSFDFLDDASTLLVGHWSGHLSLVDRRTPGTSYEKFINSSLEKIRTVHVHPLSRQYFITAGLRDVHVYDVRCLKSGKSQPLISLTEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSSLSSQFPLVSTIRHNTITGRWLTRFQAVWDPKQEDCFTVGSMAHPRRVEVFHETGKNVHSFGGECLVSVCSLSVMHPTRYILAGGNCSGRLHVFMHQET", "length": 621 }, "evidence": [ { "id": "E1BHI0", "url": "https://omabrowser.org/oma/group/E1BHI0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12510-1", "protein_name": "DNA damage-binding protein CMR1", "gene_name": "CMR1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPELTEFQKKRLENIKRNNDLLKKLHLSGVASQIKHEAGVLEKSRAPAKKKQKTTNTRATKSASPTLPTRRSRRLRGESADDVKGIPNVNDNQLLKMGSPDGQDKNFIDAIKEKPVIGDVKLSDLIKDEDESALLEKFKRFNNGNFSSGDFFEEIKKRQGDVTGMDEFDLDLYDVFQPNEIKITYERISATYFHPAMEKKLIIAGDTSGTVGFWNVRDEPLADSEEDRMEEPDITRVKLFTKNVGRIDCFPADTSKILLTSYDGSIRSVHLNNLQSEEVLTLKNEYDDSLGISDCQFSYENPNVLFLTTLGGEFTTFDTRVKKSEYNLRRLADKKIGSMAINPMRPYEIATGSLDRTLKIWDTRNLVKKPEWSQYEDYPSHEIVSTYDSRLSVSAVSYSPTDGTLVCNGYDDTIRLFDVKSRDHLSAKLEPKLTIQHNCQTGRWTSILKARFKPNKNVFAIANMKRAIDIYNSEGQQLAHLPTATVPAVISWHPLRNWIAGGNSSGKIFLFTDDSGTIKQEE", "length": 522 }, "evidence": [ { "id": "E1BHI0", "url": "https://omabrowser.org/oma/group/E1BHI0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9H967-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "WDR76", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSGAAAEKADSRQRPQMKVNEYKENQNIAYVSLRPAQTTVLIKTAKVYLAPFSLSNYQLDQLMCPKSLSEKNSNNEVACKKTKIKKTCRRIIPPKMKNTSSKAESTLQNSSSAVHTESNKLQPKRTADAMNLSVDVESSQDGDSDEDTTPSLDFSGLSPYERKRLKNISENADFFASLQLSESAARLREMIEKRQPPKSKRKKPKRENGIGCRRSMRLLKVDPSGVSLPAAPTPPTLVADETPLLPPGPLEMTSENQEDNNERFKGFLHTWAGMSKPSSKNTEKGLSSIKSYKANLNGMVISEDTVYKVTTGPIFSMALHPSETRTLVAVGAKFGQVGLCDLTQQPKEDGVYVFHPHSQPVSCLYFSPANPAHILSLSYDGTLRCGDFSRAIFEEVYRNERSSFSSFDFLAEDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLRDTHIYDARRLNSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSCISSKIPLLTTIRHNTFTGRWLTRFQAMWDPKQEDCVIVGSMAHPRRVEIFHETGKRVHSFGGEYLVSVCSINAMHPTRYILAGGNSSGKIHVFMNEKSC", "length": 626 }, "evidence": [ { "id": "E1BHI0", "url": "https://omabrowser.org/oma/group/E1BHI0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SAI7-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "DRS1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATEYERKRLENIRRNDEMLAALNVRAKASSLLSAAKRSRDDSKSFKKKKPKPASTPTVIRMSLRTRGLNPDSAGLPDGFSDFRMGSQITHNQPSPQKQSPRLLAPIPFESAYEGYGSYTQLVDTLLGIESKSCRGKLVKGEIGVVKDENESPMVRTRSSSRVSKVSVKKEEPEDDSFSDYVNKEFSIPVKPEKIEFDLDLLTLEPQNVARVVPGRIFVVQFLPCENVKMVAAGDKLGNVGFWNLDCGNEEDNDGIYLFTPHSAPVSSIVFQQNSLSRVISSSYDGLIRLMDVEKSVFDLVYSTDEAIFSLSQRPNDEQSLYFGQDYGVFNVWDLRAGKSVFHWELHERRINSIDFNPQNPHVMATSSTDGTACLWDLRSMGAKKPKTLSTVNHSRAVHSAYFSPSGLSLATTSLDNYIGVLSGANFENTCMIYHNNTSRWISKFKAVWGWDDSYIYVGNLSKKIDVINPKLKRTVMELHNPLQRAIPCRIHCHPYNVGTLAGSTAGGQVYVWTTK", "length": 516 }, "evidence": [ { "id": "E1BHI0", "url": "https://omabrowser.org/oma/group/E1BHI0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA damage checkpoint", "id": "GO:2000001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000001", "evidence": [ { "database": "UniProtKB", "id": "E1BHI0", "url": "https://www.uniprot.org/uniprotkb/E1BHI0" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "E1BHI0", "url": "https://www.uniprot.org/uniprotkb/E1BHI0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BHI0", "url": "https://www.uniprot.org/uniprotkb/E1BHI0" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "E1BHI0", "url": "https://www.uniprot.org/uniprotkb/E1BHI0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BHI0", "url": "https://www.uniprot.org/uniprotkb/E1BHI0" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "E1BHI0", "url": "https://www.uniprot.org/uniprotkb/E1BHI0" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "E1BHI0", "url": "https://www.uniprot.org/uniprotkb/E1BHI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHI0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 627, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHI0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHI0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 485, "end_pos": 487 }, { "start_pos": 617, "end_pos": 619 } ] }, "class_list": [], "section_stats": [ { 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIM5-1", "uniprot_ac": "E1BIM5", "uniprot_id": "E1BIM5_BOVIN", "mass": { "chemical_mass": 89921.0, "monoisotopic_mass": 89921.0 }, "refseq": {}, "gene_names": [ { "name": "ARHGEF6", "type": "recommended", "evidence": [ { "id": "E1BIM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" } ] } ], "protein_names": [ { "name": "Rac/Cdc42 guanine nucleotide exchange factor 6", "type": "synonym", "evidence": [ { "id": "E1BIM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIM5", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NIH7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NIH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIM5", "url": "https://www.uniprot.org/uniprotkb/E1BIM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIM5-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSRMWLSPCSCPREVLGSIQSAVMNPEERVVTWLISLGVLDSPKKTICDPEEFLKSSLKNGVVLCKLINRLRPGSVEKYCLEPQTEADCTNNINDFLKGCAALQVEIFDPDDLYAGVNFSKVLNTLLAVNKATEDQLSERPCGRSSSLSAANSSQTNPQGAVSSTAPGLQRQSKPVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFEATPLTKNYYTVVLQNILDTEKDYAKELQSLLVTYLRPLQSNNNLSTVEFTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKTLGNVIFMSQVMVQCGTSEEKEERYLMLFSSVLIMLSASPRMSGFIYQGKIPVAGMVVTRLDEIEGNDSTFEITGNIVERIVVHCGNNQDFQDWLEHLYRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFPQGHGSSARKDSVPQVLLPEEEKLIVEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRAESSSKTSVLP", "length": 800, "header": "tr|E1BIM5-1|E1BIM5_BOVIN Isoform 1 of Rac/Cdc42 guanine nucleotide exchange factor 6 OS=Bos taurus OX=9913 GN=ARHGEF6 PE=4 SV=2 CANONICAL=E1BIM5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M910-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM5/entry#A0A3Q1M910-1", "sequence": { "sequence": "MQSRMWLSPCSCPREVLGSIQSAVMNPEERVVTWLISLGVLDSPKKTICDPEEFLKSSLKNGVVLCKLINRLRPGSVEKYCLEPQTEADCTNNINDFLKGCAALQVEIFDPDDLYAGVNFSKVLNTLLAVNKATEDQLSERPCGRSSSLSAANSSQTNPQGAVSSTAPGLQRQSKPVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFEATPLTKNYYTVVLQNILDTEKDYAKELQSLLVTYLRPLQSNNNLSTVEFTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKTLGNVIFMSQVMVQCGTSEEKEERYLMLFSSVLIMLSASPRMSGFIYQGKIPVAGMVVTRLDEIEGNDSTFEITGNIVERIVVHCGNNQDFQDWLEHLYRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKEESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFPQGHGSSARKDSVPQVLLPEEEKLIVEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRAESSSKTSVLP", "length": 793, "header": "tr|A0A3Q1M910-1|E1BIM5_BOVIN Computationally mapped isoform of Rac/Cdc42 guanine nucleotide exchange factor 6 OS=Bos taurus OX=9913 GN=ARHGEF6 PE=4 SV=2 CANONICAL=E1BIM5-1" }, "locus": { "chromosome": "X", "start_pos": 20394902, "end_pos": 20279986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082494.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082494.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064945.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064945.2" } ] } }, { "isoform_ac": "A0A3Q1NIH7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM5/entry#A0A3Q1NIH7-1", "sequence": { "sequence": "MSHCWTLFLTGPFPSVSAGESFVYLAAQFELVRRLKRILIFDPDDLYAGVNFSKVLNTLLAVNKATEDQLSERPCGRSSSLSAANSSQTNPQGAVSSTAPGLQRQSKPVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFEATPLTKNYYTVVLQNILDTEKDYAKELQSLLVTYLRPLQSNNNLSTVEFTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKTLGNVIFMSQVMVQCGTSEEKEERYLMLFSSVLIMLSASPRMSGFIYQGKIPVAGMVVTRLDEIEGNDSTFEITGNIVERIVVHCGNNQDFQDWLEHLYRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKEESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFPQGHGSSARKDSVPQVLLPEEEKLIVEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRAESSSKTSVLP", "length": 725, "header": "tr|A0A3Q1NIH7-1|E1BIM5_BOVIN Computationally mapped isoform of Rac/Cdc42 guanine nucleotide exchange factor 6 OS=Bos taurus OX=9913 GN=ARHGEF6 PE=4 SV=2 CANONICAL=E1BIM5-1" }, "locus": { "chromosome": "X", "start_pos": 20384356, "end_pos": 20279986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069262.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069262.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071827.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071827.2" } ] } }, { "isoform_ac": "E1BIM5-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM5/entry#E1BIM5-1", "sequence": { "sequence": "MQSRMWLSPCSCPREVLGSIQSAVMNPEERVVTWLISLGVLDSPKKTICDPEEFLKSSLKNGVVLCKLINRLRPGSVEKYCLEPQTEADCTNNINDFLKGCAALQVEIFDPDDLYAGVNFSKVLNTLLAVNKATEDQLSERPCGRSSSLSAANSSQTNPQGAVSSTAPGLQRQSKPVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFEATPLTKNYYTVVLQNILDTEKDYAKELQSLLVTYLRPLQSNNNLSTVEFTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKTLGNVIFMSQVMVQCGTSEEKEERYLMLFSSVLIMLSASPRMSGFIYQGKIPVAGMVVTRLDEIEGNDSTFEITGNIVERIVVHCGNNQDFQDWLEHLYRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFPQGHGSSARKDSVPQVLLPEEEKLIVEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRAESSSKTSVLP", "length": 800, "header": "tr|E1BIM5-1|E1BIM5_BOVIN Isoform 1 of Rac/Cdc42 guanine nucleotide exchange factor 6 OS=Bos taurus OX=9913 GN=ARHGEF6 PE=4 SV=2 CANONICAL=E1BIM5-1" }, "locus": { "chromosome": "X", "start_pos": 20394902, "end_pos": 20279986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023731.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023731.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023731.6", "url": "https://www.ensembl.org/id/ENSBTAP00000023731.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-BTA-446388", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446388", "resource": "Reactome", "description": "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components" }, { "id": "R-BTA-8964616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8964616", "resource": "Reactome", "description": "G beta:gamma signalling through CDC42" }, { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-BTA-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "E1BIM5", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BIM5", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "E1BIM5", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BIM5", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" } ], "pmid": "" }, { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "E1BIM5", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E1BIM5", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIM5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 800, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIM5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIM5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 135, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BIM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 265, "end_pos": 445, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BIM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 467, "end_pos": 572, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BIM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM5" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 184, "end_pos": 243, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 153, "end_pos": 155 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 536, "end_pos": 538 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHP0-1", "uniprot_ac": "E1BHP0", "uniprot_id": "E1BHP0_BOVIN", "mass": { "chemical_mass": 113046.0, "monoisotopic_mass": 113046.0 }, "refseq": {}, "gene_names": [ { "name": "LOC523503", "type": "recommended", "evidence": [ { "id": "E1BHP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP0" } ] } ], "protein_names": [ { "name": "Alpha-mannosidase", "type": "recommended", "evidence": [ { "id": "E1BHP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP0/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.-", "type": "synonym", "evidence": [ { "id": "E1BHP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Specifically cleaves terminal alpha 1,6-linked mannose residues on Man3GlcNAc and Man2GlcNAc core oligosaccharides generated by N-glycan degradation pathways, having little activity, if any, on larger mannose oligosaccharides. Does not cleave terminal alpha 1,6-linked mannose on Man3GlcNAc2, and is also unable to hydrolyze terminal alpha 1,3-mannose linkages.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1NJ35", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJ35#function" }, { "database": "UniProtKB", "id": "ARBA00094269", "url": "https://www.uniprot.org/uniprotkb/ARBA00094269#function" }, { "database": "UniProtKB", "id": "E1BHP0", "url": "https://www.uniprot.org/uniprotkb/E1BHP0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHP0", "url": "https://www.uniprot.org/uniprotkb/E1BHP0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC523503", "url": "https://www.uniprot.org/uniprotkb/E1BHP0", "locus": {} } ], "crossref": [ { "id": "E1BHP0", "url": "https://alphafold.ebi.ac.uk/entry/E1BHP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006508", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006508", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000017829", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017829", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BHP0", "url": "https://www.orthodb.org/?gene=E1BHP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11607", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11607", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11607:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11607:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01074", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01074", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07748", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07748", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "84971", "url": "https://www.rhea-db.org/rhea/84971", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "84987", "url": "https://www.rhea-db.org/rhea/84987", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M2K2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NJ35", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJ35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NJ35-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJ35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHP0", "url": "https://www.uniprot.org/uniprotkb/E1BHP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHP0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSVLTQLLLLWLLGTQPEATIRVFVVPHSHLDVGWLHTVQGSTQAYVTTVYTSVVEDLTRNKQHRFIIVDQEFFRLWWDGVASAKQKVQVRQLVDQGRLEFVLGGQVMHDEAVTHVDDQILQLTEGHRFLYETFGIRPQFSWQVDSFGASATTPTLFALAGFNGHIISRIDYDLKETMQQDQEMQFVWRGSRSLLAQQEIFTHVLDENGYCLPSQQGVSSNIPLLLSKGFYWNEKAVFPDPPWDGMYPNQTVPVTLSNIQRYANTLSYNVRKRAPWFLTPHILWPWGCDRQFFNASVQFANMDYLMGYINKHVSQFGVLMVYATLSEYFQTLHSEHEPVQVRDHRDFLPYSSDMFHSWTGFYASRSGLKGLARRASALLYAGESMFTRFMLAPHRFLDRAWGLQQLQKLRWAVSEVQHHEAITGAHTPKVSDMFVGRLNNGMHGVQKLMSAIVQDRFPAHTGKQGPCLEPGGYVAVIYNPLAWTVTTIVTLTVDFPKVSVTDESGHPVPAQVQNSKEMPSVYDLLVLTTIPGLSYQYYVIKPSRRAKGDTQVTEATMANTKQFGRRPRRHDSSVGRRLVHVENDCYSVQSNQTIQVTQQFMEYEANGDEDQGPISDNYVFTSSETAKPAWETVGMEIVEGELVTEIRQYFYRTVNDRDPTYTVYSRLARGPPGADGELLCHRIEQEYRVGPLELNREAIWRTSTNLNTARVLYSDNNGYQMQRRAYKHHENNIARNYYPMTQSAFIQDRQSRLVLLSEQAHGVSSQGSGQMEVMLHRRLWALSVNVTLNDTSVVHSVLWLLLGPSTLTRDLGQRSGVALQHRPIVLIRELSETARIHPHPQHQEAVTLPPSIHLQILSIPGWTYNSNHTKHVKNLRKDNKGEAKAEFRRVLLRLHHLYEVDEDPVRSQPVTVNLQSVLQGLGSVVSVEERSLTGTWDVSTLHRWRWPTQEPGHLRGNSSHPSLHPGSFTITIHPKEIRTFFIYFKER", "length": 988, "header": "tr|E1BHP0-1|E1BHP0_BOVIN Isoform 1 of Alpha-mannosidase OS=Bos taurus OX=9913 GN=LOC523503 PE=3 SV=4 CANONICAL=E1BHP0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M2K2-1", "url": "https://www.uniprot.org/uniprotkb/E1BHP0/entry#A0A3Q1M2K2-1", "sequence": { "sequence": "ALLSPWTSPLGPLGLTGLSHHGSPRATLACPSGSTQAYVTTVYTSVVEDLTRNKQHRFIIVDQEFFRLWWDGVASAKQKVQVRQLVDQGRLEFVLGGQVMHDEAVTHVDDQILQLTEGHRFLYETFGIRPQFSWQVDSFGASATTPTLFALAGFNGHIISRIDYDLKETMQQDQEMQFVWRGSRSLLAQQEIFTHQGVSSNIPLLLSKGFYWNEKAVFPDPPWDGMYPNQTVPVTLSNIQRYANTLSYNVRKRAPWFLTPHILWPWGCDRQFFNASVQFANMDYLMGYINKHVSQFGVLMVYATLSEYFQTLHSEHEPVQVRDHRDFLPYSSDMFHSWTGFYASRSGLKGLARRASALLYAGESMFTRFMLAPHRFLDRAWGLQQLQKLRWAVSEVQHHEAITGAHTPKVSDMFVGRLNNGMHGVQKLMSAIVQDRFPAHTGLEPGGYVAVIYNPLAWTVTTIVTLTVDFPKVSVTDESGHPVPAQVQNSKEMPSVYDLLVLTTIPGLSYQYYVIKPSRRAKGDTQVTEATMANTKQFGRRPRRHDSSVGRRLVHDTNLMHSIWERQSNQTIQVTQQFMEYEANGDEDQGPISDNYVFTSSETAKPAWETVGMEIVEGELVTEIRQYFYRTVNDRDPTYTVYSRLARGPPGADGELLCHRIEQEYRVGPLELNREAIWRTSTNLNTARVLYSDNNGYQMQRRAYKHHENNIARNYYPMTQSAFIQDRQSRLVLLSEQAHGVSSQGSGQMEVMLHRRLWALSVNVTLNDTSVVHSVLWLLLGPSTLTRDLGQRSGVALQHRPIVLIRELSETARIHPHPQHQEAVTLPPSIHLQILSIPGWTYNSNHTKHVKNLRKGEAGEAKAEFRRVLLRLHHLYEVDEDPVRSQPVTVNLQSVLQGLGSVVSVEERSLTGTWDVSTLHRWRWPTQEPGHLRGLCTPGSGCPPARDSLPAPRLGSGAGQTWLRSQLCPLRPV", "length": 973, "header": "tr|A0A3Q1M2K2-1|E1BHP0_BOVIN Computationally mapped isoform of Alpha-mannosidase OS=Bos taurus OX=9913 GN=LOC523503 PE=3 SV=2 CANONICAL=E1BHP0-1" }, "locus": { "chromosome": "6", "start_pos": 102675372, "end_pos": 102633663, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066994.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066994.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062339.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062339.2" } ] } }, { "isoform_ac": "A0A3Q1NJ35-1", "url": "https://www.uniprot.org/uniprotkb/E1BHP0/entry#A0A3Q1NJ35-1", "sequence": { "sequence": "CVESGPEPIGQPLLGGAPIGVWSADLWGSMIATPSLQKGKQGSTQAYVTTVYTSVVEDLTRNKQHRFIIVDQEFFRLWWDGVASAKQKVQVRQLVDQGRLEFVLGGQVMHDEAVTHVDDQILQLTEGHRFLYETFGIRPQFSWQVDSFGASATTPTLFALAGFNGHIISRIDYDLKETMQQDQMQFVWRGSRSLLAQQEIFTHQGVSSNIPLLLSKGFYWNEKAVFPDPPWDGMYPNQTVPVTLSNIQRYANTLSYNVRKRAPWFLTPHILWPWGCDRQFFNASVQFANMDYLMGYINKHVSQFGVLMVYATLSEYFQTLHSEHEPVQVRDHRDFLPYSSDMFHSWTGFYASRSGLKGLARRASALLYAGESMFTRFMLAPHRFLDRAWGLQQLQKLRWAVSEVQHHEAITGAHTPKVSDMFVGRLNNGMHGVQKLMSAIVQDRFPAHTGLEPGGYVAVIYNPLAWTVTTIVTLTVDFPKVSVTDESGHPVPAQVQNSKEMPSVYDLLVLTTIPGLSYQYYVIKPSRRAKGDTQVTEATMANTKQFGRRPRRHDSSVGRRLVHDTNLMHSIWERQSNQTIQVTQQFMEYEANGDEDQGPISDNYVFTSSETAKPAWETVGMEIVEGELVTEIRQYFYRTVNDRDPTYTVYSRLARGPPGADGELLCHRIEQEYRVGPLELNREAIWRTSTNLNTARVLYSDNNGYQMQRRAYKHHENNIARNYYPMTQSAFIQDRQSRLVLLSEQAHGVSSQGSGQMEVMLHRRLWALSVNVTLNDTSVVHSVLWLLLGPSTLTRDLGQRSGVALQHRPIVLIRELSETARIHPHPQHQEAVTLPPSIHLQILSIPGWTYNSNHTKHVKNLRKDNKGEAKAEFRRVLLRLHHLYEVDEDPVRSQPVTVNLQSVLQGLGSVVSVEERSLTGTWDVSTLHRWRWPTQEPGHLRGNSSHPSLHPGSFTITIHPKEIRTFFIYFKER", "length": 973, "header": "tr|A0A3Q1NJ35-1|E1BHP0_BOVIN Computationally mapped isoform of Alpha-mannosidase OS=Bos taurus OX=9913 GN=LOC523503 PE=3 SV=2 CANONICAL=E1BHP0-1" }, "locus": { "chromosome": "6", "start_pos": 102676596, "end_pos": 102633277, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083266.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083266.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072102.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072102.2" } ] } }, { "isoform_ac": "E1BHP0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHP0/entry#E1BHP0-1", "sequence": { "sequence": "MGSVLTQLLLLWLLGTQPEATIRVFVVPHSHLDVGWLHTVQGSTQAYVTTVYTSVVEDLTRNKQHRFIIVDQEFFRLWWDGVASAKQKVQVRQLVDQGRLEFVLGGQVMHDEAVTHVDDQILQLTEGHRFLYETFGIRPQFSWQVDSFGASATTPTLFALAGFNGHIISRIDYDLKETMQQDQEMQFVWRGSRSLLAQQEIFTHVLDENGYCLPSQQGVSSNIPLLLSKGFYWNEKAVFPDPPWDGMYPNQTVPVTLSNIQRYANTLSYNVRKRAPWFLTPHILWPWGCDRQFFNASVQFANMDYLMGYINKHVSQFGVLMVYATLSEYFQTLHSEHEPVQVRDHRDFLPYSSDMFHSWTGFYASRSGLKGLARRASALLYAGESMFTRFMLAPHRFLDRAWGLQQLQKLRWAVSEVQHHEAITGAHTPKVSDMFVGRLNNGMHGVQKLMSAIVQDRFPAHTGKQGPCLEPGGYVAVIYNPLAWTVTTIVTLTVDFPKVSVTDESGHPVPAQVQNSKEMPSVYDLLVLTTIPGLSYQYYVIKPSRRAKGDTQVTEATMANTKQFGRRPRRHDSSVGRRLVHVENDCYSVQSNQTIQVTQQFMEYEANGDEDQGPISDNYVFTSSETAKPAWETVGMEIVEGELVTEIRQYFYRTVNDRDPTYTVYSRLARGPPGADGELLCHRIEQEYRVGPLELNREAIWRTSTNLNTARVLYSDNNGYQMQRRAYKHHENNIARNYYPMTQSAFIQDRQSRLVLLSEQAHGVSSQGSGQMEVMLHRRLWALSVNVTLNDTSVVHSVLWLLLGPSTLTRDLGQRSGVALQHRPIVLIRELSETARIHPHPQHQEAVTLPPSIHLQILSIPGWTYNSNHTKHVKNLRKDNKGEAKAEFRRVLLRLHHLYEVDEDPVRSQPVTVNLQSVLQGLGSVVSVEERSLTGTWDVSTLHRWRWPTQEPGHLRGNSSHPSLHPGSFTITIHPKEIRTFFIYFKER", "length": 988, "header": "tr|E1BHP0-1|E1BHP0_BOVIN Isoform 1 of Alpha-mannosidase OS=Bos taurus OX=9913 GN=LOC523503 PE=3 SV=4 CANONICAL=E1BHP0-1" }, "locus": { "chromosome": "6", "start_pos": 102676596, "end_pos": 102631400, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008532.6", "url": "https://www.ensembl.org/id/ENSBTAT00000008532.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008532.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008532.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BHP0", "url": "https://www.uniprot.org/uniprotkb/E1BHP0" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "E1BHP0", "url": "https://www.uniprot.org/uniprotkb/E1BHP0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BHP0", "url": "https://www.uniprot.org/uniprotkb/E1BHP0" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "E1BHP0", "url": "https://www.uniprot.org/uniprotkb/E1BHP0" } ], "pmid": "" }, { "name": "alpha-mannosidase activity", "id": "GO:0004559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004559", "evidence": [ { "database": "UniProtKB", "id": "E1BHP0", "url": "https://www.uniprot.org/uniprotkb/E1BHP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mannose metabolic process", "id": "GO:0006013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006013", "evidence": [ { "database": "UniProtKB", "id": "E1BHP0", "url": "https://www.uniprot.org/uniprotkb/E1BHP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 786, "end_pos": 788, "annotation": "n_glycosylation_sequon" }, { "start_pos": 790, "end_pos": 792, "annotation": "n_glycosylation_sequon" }, { "start_pos": 868, "end_pos": 870, "annotation": "n_glycosylation_sequon" }, { "start_pos": 958, "end_pos": 960, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "84971", "name": "", "equation": "alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-D-GlcNAc + H2O = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-D-GlcNAc + D-mannose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BHP0-1", "G5E5M8-1" ], "evidence": [ { "id": "84971", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/84971" } ] }, { "id": "84987", "name": "", "equation": "alpha-D-Man-(1->6)-beta-D-Man-(1->4)-D-GlcNAc + H2O = 4-O-beta-D-mannopyranosyl-N-acetyl-D-glucosamine + D-mannose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BHP0-1", "G5E5M8-1" ], "evidence": [ { "id": "84987", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/84987" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BHP0", "gene_name": "LOC523503", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "E1BHP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP0" } ] } ] }, { "uniprot_ac": "G5E5M8", "gene_name": "LOC532207", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "G5E5M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5M8" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHP0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 988, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHP0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHP0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP0" }, { "id": "SM00872", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00872" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycoside hydrolase family 38 central", "eco_id": "ECO_0000259", "start_pos": 357, "end_pos": 439, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 250, "end_pos": 252 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 592, "end_pos": 594 }, { "start_pos": 786, "end_pos": 788 }, { "start_pos": 790, "end_pos": 792 }, { "start_pos": 868, "end_pos": 870 }, { "start_pos": 958, "end_pos": 960 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFE2-1", "uniprot_ac": "E1BFE2", "uniprot_id": "E1BFE2_BOVIN", "mass": { "chemical_mass": 248246.0, "monoisotopic_mass": 248246.0 }, "refseq": { "ac": "NP_001192226", "name": "receptor-type tyrosine-protein phosphatase beta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192226" }, "gene_names": [ { "name": "PTPRB", "type": "recommended", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] }, { "name": "PTPRB", "type": "synonym", "evidence": [ { "id": "NP_001192226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192226" } ] } ], "protein_names": [ { "name": "protein-tyrosine-phosphatase", "type": "recommended", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2/entry#names_and_taxonomy" } ] }, { "name": "receptor-type tyrosine-protein phosphatase beta", "type": "synonym", "evidence": [ { "id": "NP_001192226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192226" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFE2", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PTPRB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2", "locus": { "chromosome": "5", "start_pos": 43011958, "end_pos": 42885224, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015296", "url": "https://www.ensembl.org/id/ENSBTAG00000015296" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015296", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015296", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14617", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14617", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23409", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23409", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505696", "url": "https://www.ncbi.nlm.nih.gov/gene/505696", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505696", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505696", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BFE2", "url": "https://www.orthodb.org/?gene=E1BFE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18861", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18861", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192226", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192226", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RXC7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXC7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S974", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S974", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S974-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S974-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SC05", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SC05-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQG5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQG5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T282", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T282", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T282-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T282-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBI8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBI8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUX8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUX8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFE2", "url": "https://www.uniprot.org/uniprotkb/E1BFE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFE2-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAEFYMAILTCFIFVNSEGFQIVHVQKQQCLFKNGRVVMDLCNRTNQNQQWMWTEDGKLLHVKSALCLGISNSSGGPGRAAIFAPCSQAPRWTCYEKEGFLEVENASLFLKKQGVRVVVKKGRKYLHSWMKIDVNEEGKPVNESLCSKKAGPGTEVSVRSIRNTAPPQTPTTFNALPYSLGHLIRNTTEAFTRSTPENYSQNSSQSQHLSLWMAGMTSWVPWTTPPFSSTTEETGLGEPVRCNFTLTESRVSSRSVSLQWRTLAFPCNFNLTYSSDTSGVAWCHPVRIDNTTYGCNSEDLQAGTIYNFTIMSLDGEKKTMVLQTDPLPPARFEVSKEKTTTTSLHVWWTPSSGKVTWYEVQLLDDNQKIQTAQIQERASRNEYTFFNLTAGNKYNIAITAVSGDKRSSTMYANGSTVPSPVKDIGVLAKTNSLLISWSRGSGNVERYQLMLMDKGILVHSIAVDTTFYTFHGLTPGHLYNVTIVSEAAGLQNYKWKSARTTPMEVSNLKVTNEGTMTSLKVKWQRPSGNVDFYNITLSYQGTIKQSRTLASQITESQFKDLAPGRLYQVTVSCVSGELSAHRTAVGRTVPQKVGDLEANSNGSTKSLVVSWSPPAGDWEQYRILLWNDSSVLLNITVGKEETHYVIDDVGLIPGRRYEIEVTVESGNLKNSTRCQGRTVPLAVLHLRVKHANETSLSVMWQTPAAEWERYIVSLIDRDLLFIHKLLPRDAREFTFTNLVPGRKYIATVTSISGDLKNSSLTKGRTVPAQVTGLRVANQGTTNSLFTNWTQALGDVEFYQVLLIHENVVIKNESVSSETSGYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRSDYLSISWLPAPGDVDSYVVTLSHDGRVVQSLVIAKSVGECSFSSLTPGRLYNVTITTRSGKYESHSFSQERTVPNKVQGVSISNSARSDYLKVSWVHASGDFDHYEVTIKNKNNFIQTKSVPKSENECIFVKLVPGRLYSVTVSTKSGQYEASEQGNGRTIPEAVKDLTLKNRSTEDLWVTWTRADGDVDQYEIQLLFNDMKVFPPFHLVSTATEYRFTSLTPGRKYKILVLTISGDVQQSAFIEGFTVPSVVKNIHVSPSGATDSLTVNWTPGGGDVDSYVVSAFRQNQMVESQTVLKHISEHTFQRLEAGEQYRIVIASVSGSQKNQIDVLGRTIPASVQGITADNVYSSHSLIVSWQKAVGMAERYDILLLSENGILLSNTSEAATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTNLRITENSTRHLSFSWTPSEGELNSYNIFLYNPDRTLKDRALVDPQVQSFSFQNLLQGRMYRMVIVTHSGELSNESFIFGRTVPATVSNLKGSNQNMTDSLWFSWSPAPGDFDFYELILYNPNGTKKENWKDKDLTQWRFHGLVPGRKYTLCVITHSGDLSNKATGESRTAPSPPSLMSFADVTNTSLAITWKGPPDWTDYDDFELQWFPRDAITVFNPYSNRKSEGRIVHGLRPGRSYQFSVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNKKDVLISKSSINFTFNCSWFSDTNGAVKYFTVVVREADGNDELKPEPQHPLPSYLEYRHNASIRVYQTDYFASKCAESPDSNSKSFNIKLGAEMESLGGKCDPNQQKFCDGPLKPRTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGVIEGVSAGLFLIGMLVAVVALFICRRKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKVNQFEGHFMKLQADSNYLLSKEYEDLKDVGRNQSCDIALLPENRGKNRYNNILPYDSSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFRICSEEQLDAHRLIRHFHYTVWPDHGVPESTQSLIQFVRTVRDYINRTPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDSGYSRH", "length": 2211, "header": "tr|E1BFE2-1|E1BFE2_BOVIN Isoform 1 of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPRB PE=3 SV=4 CANONICAL=E1BFE2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RXC7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE2/entry#A0AAA9RXC7-1", "sequence": { "sequence": "MRSHGAGLALWTALSLLQTGLGEPVRCNFTLTESRVSSRSVSLQWRTLAFPCNFNLTYSSDTSGVAWCHPVRIDNTTYGCNSEDLQAGTIYNFTIMSLDGEKKTMVLQTDPLPPARFEVSKEKTTTTSLHVWWTPSSGKVTWYEVQLLDDNQKIQTAQIQERASRNEYTFFNLTAGNKYNIAITAVSGDKRSSTMYANGSTVPSPVKDIGVLAKTNSLLISWSRGSGNVERYQLMLMDKGILVHSIAVDTTFYTFHGLTPGHLYNVTIVSEAAGLQNYKWKSARTTPMEVSNLKVTNEGTMTSLKVKWQRPSGNVDFYNITLSYQGTIKQSRTLASQITESQFKDLAPGRLYQVTVSCVSGELSAHRTAVGRTVPQKVGDLEANSNGSTKSLVVSWSPPAGDWEQYRILLWNDSSVLLNITVGKEETHYVIDDVGLIPGRRYEIEVTVESGNLKNSTRCQGRTVPLAVLHLRVKHANETSLSVMWQTPAAEWERYIVSLIDRDLLFIHKLLPRDAREFTFTNLVPGRKYIATVTSISGDLKNSSLTKGRTVPAQVTGLRVANQGTTNSLFTNWTQALGDVEFYQVLLIHENVVIKNESVSSETSGYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRSDYLSISWLPAPGDVDSYVVTLSHDGRVVQSLVIAKSVGECSFSSLTPGRLYNVTITTRSGKYESHSFSQERTVPNKVQGVSISNSARSDYLKVSWVHASGDFDHYEVTIKNKNNFIQTKSVPKSENECIFVKLVPGRLYSVTVSTKSGQYEASEQGNGRTIPEAVKDLTLKNRSTEDLWVTWTRADGDVDQYEIQLLFNDMKVFPPFHLVSTATEYRFTSLTPGRKYKILVLTISGDVQQSAFIEGFTVPSVVKNIHVSPSGATDSLTVNWTPGGGDVDSYVVSAFRQNQMVESQTVLKHISEHTFQRLEAGEQYRIVIASVSGSQKNQIDVLGRTIPASVQGITADNVYSSHSLIVSWQKAVGMAERYDILLLSENGILLSNTSEAATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTNLRITENSTRHLSFSWTPSEGELNSYNIFLYNPDRTLKDRALVDPQVQSFSFQNLLQGRMYRMVIVTHSGELSNESFIFGRTVPATVSNLKGSNQNMTDSLWFSWSPAPGDFDFYELILYNPNGTKKENWKDKDLTQWRFHGLVPGRKYTLCVITHSGDLSNKATGESRTAPSPPSLMSFADVTNTSLAITWKGPPDWTDYDDFELQWFPRDAITVFNPYSNRKSEGRIVHGLRPGRSYQFSVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNKKDVLISKSSINFTFNCSWFSDTNGAVKYFTVVVREADGNDELKPEPQHPLPSYLEYRHNASIRVYQTDYFASKCAESPDSNSKSFNIKLGAEMESLGGKCDPNQQKFCDGPLKPRTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGVIEGVSAGLFLIGMLVAVVALFICRRKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKVNQFEGHFMKLQADSNYLLSKEYEDLKDVGRNQSCDIALLPENRGKNRYNNILPYDSSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFRICSEEQLDAHRLIRHFHYTVWPDHGVPESTQSLIQFVRTVRDYINRTPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDSGYSRH", "length": 1995, "header": "tr|A0AAA9RXC7-1|E1BFE2_BOVIN Computationally mapped isoform of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPRB PE=3 SV=1 CANONICAL=E1BFE2-1" }, "locus": { "chromosome": "5", "start_pos": 43010553, "end_pos": 42921020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116501.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116501.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077151.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077151.1" } ] } }, { "isoform_ac": "A0AAA9S974-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE2/entry#A0AAA9S974-1", "sequence": { "sequence": "MHGLRLGPGTGLGEPVRCNFTLTESRVSSRSVSLQWRTLAFPCNFNLTYSSDTSGVAWCHPVRIDNTTYGCNSEDLQAGTIYNFTIMSLDGEKKTMVLQTDPLPPARFEVSKEKTTTTSLHVWWTPSSGKVTWYEVQLLDDNQKIQTAQIQERASRNEYTFFNLTAGNKYNIAITAVSGDKRSSTMYANGSTVPSPVKDIGVLAKTNSLLISWSRGSGNVERYQLMLMDKGILVHSIAVDTTFYTFHGLTPGHLYNVTIVSEAAGLQNYKWKSARTTPMEVSNLKVTNEGTMTSLKVKWQRPSGNVDFYNITLSYQGTIKQSRTLASQITESQFKDLAPGRLYQVTVSCVSGELSAHRTAVGRTVPQKVGDLEANSNGSTKSLVVSWSPPAGDWEQYRILLWNDSSVLLNITVGKEETHYVIDDVGLIPGRRYEIEVTVESGNLKNSTRCQGRTVPLAVLHLRVKHANETSLSVMWQTPAAEWERYIVSLIDRDLLFIHKLLPRDAREFTFTNLVPGRKYIATVTSISGDLKNSSLTKGRTVPAQVTGLRVANQGTTNSLFTNWTQALGDVEFYQVLLIHENVVIKNESVSSETSGYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRSDYLSISWLPAPGDVDSYVVTLSHDGRVVQSLVIAKSVGECSFSSLTPGRLYNVTITTRSGKYESHSFSQERTVPNKVQGVSISNSARSDYLKVSWVHASGDFDHYEVTIKNKNNFIQTKSVPKSENECIFVKLVPGRLYSVTVSTKSGQYEASEQGNGRTIPEAVKDLTLKNRSTEDLWVTWTRADGDVDQYEIQLLFNDMKVFPPFHLVSTATEYRFTSLTPGRKYKILVLTISGDVQQSAFIEGFTVPSVVKNIHVSPSGATDSLTVNWTPGGGDVDSYVVSAFRQNQMVESQTVLKHISEHTFQRLEAGEQYRIVIASVSGSQKNQIDVLGRTIPASVQGITADNVYSSHSLIVSWQKAVGMAERYDILLLSENGILLSNTSEAATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTNLRITENSTRHLSFSWTPSEGELNSYNIFLYNPDRTLKDRALVDPQVQSFSFQNLLQGRMYRMVIVTHSGELSNESFIFGRTVPATVSNLKGSNQNMTDSLWFSWSPAPGDFDFYELILYNPNGTKKENWKDKDLTQWRFHGLVPGRKYTLCVITHSGDLSNKATGESRTAPSPPSLMSFADVTNTSLAITWKGPPDWTDYDDFELQWFPRDAITVFNPYSNRKSEGRIVHGLRPGRSYQFSVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNKKDVLISKSSINFTFNCSWFSDTNGAVKYFTVVVREADGNDELKPEPQHPLPSYLEYRHNASIRVYQTDYFASKCAESPDSNSKSFNIKLGAEMESLGGKCDPNQQKFCDGPLKPRTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGVIEGVSAGLFLIGMLVAVVALFICRRKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKVNQFEGHFMKLQADSNYLLSKEYEDLKDVGRNQSCDIALLPENRGKNRYNNILPYDSSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFRICSEEQLDAHRLIRHFHYTVWPDHGVPESTQSLIQFVRTVRDYINRTPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDSGYSRH", "length": 1986, "header": "tr|A0AAA9S974-1|E1BFE2_BOVIN Computationally mapped isoform of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPRB PE=3 SV=1 CANONICAL=E1BFE2-1" }, "locus": { "chromosome": "5", "start_pos": 43010553, "end_pos": 42921359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115288.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115288.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080479.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080479.1" } ] } }, { "isoform_ac": "A0AAA9SC05-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE2/entry#A0AAA9SC05-1", "sequence": { "sequence": "MRSHGAGLALWTALSLLQTGLGEPVRCNFTLTESRVSSRSVSLQWRTLAFPCNFNLTYSSDTSGVAWCHPVRIDNTTYGCNSEDLQAGTIYNFTIMSLDGEKKTMVLQTDPLPPARFEVSKEKTTTTSLHVWWTPSSGKVTWYEVQLLDDNQKIQTAQIQERASRNEYTFFNLTAGNKYNIAITAVSGDKRSSTMYANGSTVPSPVKDIGVLAKTNSLLISWSRGSGNVERYQLMLMDKGILVHSIAVDTTFYTFHGLTPGHLYNVTIVSEAAGLQNYKWKSARTTPMEVSNLKVTNEGTMTSLKVKWQRPSGNVDFYNITLSYQGTIKQSRTLASQITESQFKDLAPGRLYQVTVSCVSGELSAHRTAVGRTVPQKVGDLEANSNGSTKSLVVSWSPPAGDWEQYRILLWNDSSVLLNITVGKEETHYVIDDVGLIPGRRYEIEVTVESGNLKNSTRCQGRTVPLAVLHLRVKHANETSLSVMWQTPAAEWERYIVSLIDRDLLFIHKLLPRDAREFTFTNLVPGRKYIATVTSISGDLKNSSLTKGRTVPAQVTGLRVANQGTTNSLFTNWTQALGDVEFYQVLLIHENVVIKNESVSSETSGYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRSDYLSISWLPAPGDVDSYVVTLSHDGRVVQSLVIAKSVGECSFSSLTPGRLYNVTITTRSGKYESHSFSQERTVPNKVQGVSISNSARSDYLKVSWVHASGDFDHYEVTIKNKNNFIQTKSVPKSENECIFVKLVPGRLYSVTVSTKSGQYEASEQGNGRTIPEAVKDLTLKNRSTEDLWVTWTRADGDVDQYEIQLLFNDMKVFPPFHLVSTATEYRFTSLTPGRKYKILVLTISGDVQQSAFIEGFTVPSVVKNIHVSPSGATDSLTVNWTPGGGDVDSYVVSAFRQNQMVESQTVLKHISEHTFQRLEAGEQYRIVIASVSGSQKNQIDVLGRTIPAAVTNLRITENSTRHLSFSWTPSEGELNSYNIFLYNPDRTLKDRALVDPQVQSFSFQNLLQGRMYRMVIVTHSGELSNESFIFGRTVPATVSNLKGSNQNMTDSLWFSWSPAPGDFDFYELILYNPNGTKKENWKDKDLTQWRFHGLVPGRKYTLCVITHSGDLSNKATGESRTAPSPPSLMSFADVTNTSLAITWKGPPDWTDYDDFELQWFPRDAITVFNPYSNRKSEGRIVHGLRPGRSYQFSVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNKKDVLISKSSINFTFNCSWFSDTNGAVKYFTVVVREADGNDELKPEPQHPLPSYLEYRHNASIRVYQTDYFASKCAESPDSNSKSFNIKLGAEMESLGGKCDPNQQKFCDGPLKPRTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGVIEGVSAGLFLIGMLVAVVALFICRRKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKVNQFEGHFMKLQADSNYLLSKEYEDLKDVGRNQSCDIALLPENRGKNRYNNILPYDSSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFRICSEEQLDAHRLIRHFHYTVWPDHGVPESTQSLIQFVRTVRDYINRTPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDSGYSRH", "length": 1905, "header": "tr|A0AAA9SC05-1|E1BFE2_BOVIN Computationally mapped isoform of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPRB PE=3 SV=1 CANONICAL=E1BFE2-1" }, "locus": { "chromosome": "5", "start_pos": 43010553, "end_pos": 42921020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094928.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094928.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081047.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081047.1" } ] } }, { "isoform_ac": "A0AAA9SQG5-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE2/entry#A0AAA9SQG5-1", "sequence": { "sequence": "MDGWNDILGSLDYSTLLQHHGRDPLPPARFEVSKEKTTTTSLHVWWTPSSGKVTWYEVQLLDDNQKIQTAQIQERASRNEYTFFNLTAGNKYNIAITAVSGDKRSSTMYANGSTVPSPVKDIGVLAKTNSLLISWSRGSGNVERYQLMLMDKGILVHSIAVDTTFYTFHGLTPGHLYNVTIVSEAAGLQNYKWKSARTTPMEVSNLKVTNEGTMTSLKVKWQRPSGNVDFYNITLSYQGTIKQSRTLASQITESQFKDLAPGRLYQVTVSCVSGELSAHRTAVGRTVPQKVGDLEANSNGSTKSLVVSWSPPAGDWEQYRILLWNDSSVLLNITVGKEETHYVIDDVGLIPGRRYEIEVTVESGNLKNSTRCQGRTVPLAVLHLRVKHANETSLSVMWQTPAAEWERYIVSLIDRDLLFIHKLLPRDAREFTFTNLVPGRKYIATVTSISGDLKNSSLTKGRTVPAQVTGLRVANQGTTNSLFTNWTQALGDVEFYQVLLIHENVVIKNESVSSETSGYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRSDYLSISWLPAPGDVDSYVVTLSHDGRVVQSLVIAKSVGECSFSSLTPGRLYNVTITTRSGKYESHSFSQERTVPNKVQGVSISNSARSDYLKVSWVHASGDFDHYEVTIKNKNNFIQTKSVPKSENECIFVKLVPGRLYSVTVSTKSGQYEASEQGNGRTIPEAVKDLTLKNRSTEDLWVTWTRADGDVDQYEIQLLFNDMKVFPPFHLVSTATEYRFTSLTPGRKYKILVLTISGDVQQSAFIEGFTVPSVVKNIHVSPSGATDSLTVNWTPGGGDVDSYVVSAFRQNQMVESQTVLKHISEHTFQRLEAGEQYRIVIASVSGSQKNQIDVLGRTIPASVQGITADNVYSSHSLIVSWQKAVGMAERYDILLLSENGILLSNTSEAATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTNLRITENSTRHLSFSWTPSEGELNSYNIFLYNPDRTLKDRALVDPQVQSFSFQNLLQGRMYRMVIVTHSGELSNESFIFGRTVPATVSNLKGSNQNMTDSLWFSWSPAPGDFDFYELILYNPNGTKKENWKDKDLTQWRFHGLVPGRKYTLCVITHSGDLSNKATGESRTAPSPPSLMSFADVTNTSLAITWKGPPDWTDYDDFELQWFPRDAITVFNPYSNRKSEGRIVHGLRPGRSYQFSVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNKKDVLISKSSINFTFNCSWFSDTNGAVKYFTVVVREADGNDELKPEPQHPLPSYLEYRHNASIRVYQTDYFASKCAESPDSNSKSFNIKLGAEMESLGGKCDPNQQKFCDGPLKPRTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGVIEGVSAGLFLIGMLVAVVALFICRRKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKVNQFEGHFMKLQADSNYLLSKEYEDLKDVGRNQSCDIALLPENRGKNRYNNILPYDSSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFRICSEEQLDAHRLIRHFHYTVWPDHGVPESTQSLIQFVRTVRDYINRTPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDSGYSRH", "length": 1908, "header": "tr|A0AAA9SQG5-1|E1BFE2_BOVIN Computationally mapped isoform of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPRB PE=3 SV=1 CANONICAL=E1BFE2-1" }, "locus": { "chromosome": "5", "start_pos": 43010553, "end_pos": 42897519, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089699.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089699.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086260.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086260.1" } ] } }, { "isoform_ac": "A0AAA9T282-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE2/entry#A0AAA9T282-1", "sequence": { "sequence": "MRSHGAGLALWTALSLLQTGLGEPVRCNFTLTESRVSSRSVSLQWRTLAFPCNFNLTYSSDTSGVAWCHPVRIDNTTYGCNSEDLQAGTIYNFTIMSLDGEKKTMVLQTDPLPPARFEVSKEKTTTTSLHVWWTPSSGKVTWYEVQLLDDNQKIQTAQIQERASRNEYTFFNLTAGNKYNIAITAVSGDKRSSTMYANGSTVPSPVKDIGVLAKTNSLLISWSRGSGNVERYQLMLMDKGILVHSIAVDTTFYTFHGLTPGHLYNVTIVSEAAGLQNYKWKSARTTPMEVSNLKVTNEGTMTSLKVKWQRPSGNVDFYNITLSYQGTIKQSRTLASQITESQFKDLAPGRLYQVTVSCVSGELSAHRTAVGRTVPLAVLHLRVKHANETSLSVMWQTPAAEWERYIVSLIDRDLLFIHKLLPRDAREFTFTNLVPGRKYIATVTSISGDLKNSSLTKGRTVPAQVTGLRVANQGTTNSLFTNWTQALGDVEFYQVLLIHENVVIKNESVSSETSGYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRSDYLSISWLPAPGDVDSYVVTLSHDGRVVQSLVIAKSVGECSFSSLTPGRLYNVTITTRSGKYESHSFSQERTVPNKVQGVSISNSARSDYLKVSWVHASGDFDHYEVTIKNKNNFIQTKSVPKSENECIFVKLVPGRLYSVTVSTKSGQYEASEQGNGRTIPEAVKDLTLKNRSTEDLWVTWTRADGDVDQYEIQLLFNDMKVFPPFHLVSTATEYRFTSLTPGRKYKILVLTISGDVQQSAFIEGFTVPSVVKNIHVSPSGATDSLTVNWTPGGGDVDSYVVSAFRQNQMVESQTVLKHISEHTFQRLEAGEQYRIVIASVSGSQKNQIDVLGRTIPASVQGITADNVYSSHSLIVSWQKAVGMAERYDILLLSENGILLSNTSEAATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTNLRITENSTRHLSFSWTPSEGELNSYNIFLYNPDRTLKDRALVDPQVQSFSFQNLLQGRMYRMVIVTHSGELSNESFIFGRTVPATVSNLKGSNQNMTDSLWFSWSPAPGDFDFYELILYNPNGTKKENWKDKDLTQWRFHGLVPGRKYTLCVITHSGDLSNKATGESRTAPSPPSLMSFADVTNTSLAITWKGPPDWTDYDDFELQWFPRDAITVFNPYSNRKSEGRIVHGLRPGRSYQFSVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNKKDVLISKSSINFTFNCSWFSDTNGAVKYFTVVVREADGNDELKPEPQHPLPSYLEYRHNASIRVYQTDYFASKCAESPDSNSKSFNIKLGAEMESLGGKCDPNQQKFCDGPLKPRTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGVIEGVSAGLFLIGMLVAVVALFICRRKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKVNQFEGHFMKLQADSNYLLSKEYEDLKDVGRNQSCDIALLPENRGKNRYNNILPYDSSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFRICSEEQLDAHRLIRHFHYTVWPDHGVPESTQSLIQFVRTVRDYINRTPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDSGYSRH", "length": 1905, "header": "tr|A0AAA9T282-1|E1BFE2_BOVIN Computationally mapped isoform of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPRB PE=3 SV=1 CANONICAL=E1BFE2-1" }, "locus": { "chromosome": "5", "start_pos": 43010553, "end_pos": 42921020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093228.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093228.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089762.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089762.1" } ] } }, { "isoform_ac": "A0AAA9TBI8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE2/entry#A0AAA9TBI8-1", "sequence": { "sequence": "MEAEFYMAILTCFIFVNSEGFQIVHVQKQQCLFKNGRVVMDLCNRTNQNQQWMWTEDGKLLHVKSALCLGISNSSGGPGRAAIFAPCSQAPRWTCYEKEGFLEVENASLFLKKQGVRVVVKKGRKYLHSWMKIDVNEEGKPVNESLCSKKAGPGTEVSVRSIRNTAPPQTPTTFNALPYSLGHLIRNTTEAFTRSTPENYSQNSSQSQHLSLWMAGMTSWVPWTTPPFSSTTEETGLGEPVRCNFTLTESRVSSRSVSLQWRTLAFPCNFNLTYSSDTSGVAWCHPVRIDNTTYGCNSEDLQAGTIYNFTIMSLDGEKKTMVLQTDPLPPARFEVSKEKTTTTSLHVWWTPSSGKVTWYEVQLLDDNQKIQTAQIQERASRNEYTFFNLTAGNKYNIAITAVSGDKRSSTMYANGSTVPSPVKDIGVLAKTNSLLISWSRGSGNVERYQLMLMDKGILVHSIAVDTTFYTFHGLTPGHLYNVTIVSEAAGLQNYKWKSARTTPMEVSNLKVTNEGTMTSLKVKWQRPSGNVDFYNITLSYQGTIKQSRTLASQITESQFKDLAPGRLYQVTVSCVSGELSAHRTAVGRTVPQKVGDLEANSNGSTKSLVVSWSPPAGDWEQYRILLWNDSSVLLNITVGKEETHYVIDDVGLIPGRRYEIEVTVESGNLKNSTRCQGRTVPLAVLHLRVKHANETSLSVMWQTPAAEWERYIVSLIDRDLLFIHKLLPRDAREFTFTNLVPGRKYIATVTSISGDLKNSSLTKGRTVPAQVTGLRVANQGTTNSLFTNWTQALGDVEFYQVLLIHENVVIKNESVSSETSGYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPNKVQGVSISNSARSDYLKVSWVHASGDFDHYEVTIKNKNNFIQTKSVPKSENECIFVKLVPGRLYSVTVSTKSGQYEASEQGNGRTIPEAVKDLTLKNRSTEDLWVTWTRADGDVDQYEIQLLFNDMKVFPPFHLVSTATEYRFTSLTPGRKYKILVLTISGDVQQSAFIEGFTVPSVVKNIHVSPSGATDSLTVNWTPGGGDVDSYVVSAFRQNQMVESQTVLKHISEHTFQRLEAGEQYRIVIASVSGSQKNQIDVLGRTIPASVQGITADNVYSSHSLIVSWQKAVGMAERYDILLLSENGILLSNTSEAATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTNLRITENSTRHLSFSWTPSEGELNSYNIFLYNPDRTLKDRALVDPQVQSFSFQNLLQGRMYRMVIVTHSGELSNESFIFGRTVPATVSNLKGSNQNMTDSLWFSWSPAPGDFDFYELILYNPNGTKKENWKDKDLTQWRFHGLVPGRKYTLCVITHSGDLSNKATGESRTAPSPPSLMSFADVTNTSLAITWKGPPDWTDYDDFELQWFPRDAITVFNPYSNRKSEGRIVHGLRPGRSYQFSVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNKKDVLISKSSINFTFNCSWFSDTNGAVKYFTVVVREADGNDELKPEPQHPLPSYLEYRHNASIRVYQTDYFASKCAESPDSNSKSFNIKLGAEMESLGGKCDPNQQKFCDGPLKPRTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGVIEGVSAGLFLIGMLVAVVALFICRRKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKVNQFEGHFMKLQADSNYLLSKEYEDLKDVGRNQSCDIALLPENRGKNRYNNILPYDSSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFRICSEEQLDAHRLIRHFHYTVWPDHGVPESTQSLIQFVRTVRDYINRTPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDSGYSRH", "length": 2123, "header": "tr|A0AAA9TBI8-1|E1BFE2_BOVIN Computationally mapped isoform of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPRB PE=3 SV=1 CANONICAL=E1BFE2-1" }, "locus": { "chromosome": "5", "start_pos": 43010553, "end_pos": 42885405, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115915.2", "url": "https://www.ensembl.org/id/ENSBTAT00000115915.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094046.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094046.1" } ] } }, { "isoform_ac": "A0ABI0NUX8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE2/entry#A0ABI0NUX8-1", "sequence": { "sequence": "MRSHGAGLALWTALSLLQTGLGEPVRCNFTLTESRVSSRSVSLQWRTLAFPCNFNLTYSSDTSGVAWCHPVRIDNTTYGCNSEDLQAGTIYNFTIMSLDGEKKTMVLQTDPLPPARFEVSKEKTTTTSLHVWWTPSSGKVTWYEVQLLDDNQKIQTAQIQERASRNEYTFFNLTAGNKYNIAITAVSGDKRSSTMYANGSTVPSPVKDIGVLAKTNSLLISWSRGSGNVERYQLMLMDKGILVHSIAVDTTFYTFHGLTPGHLYNVTIVSEAAGLQNYKWKSARTTPMEVSNLKVTNEGTMTSLKVKWQRPSGNVDFYNITLSYQGTIKQSRTLASQITESQFKDLAPGRLYQVTVSCVSGELSAHRTAVGRTVPQKVGDLEANSNGSTKSLVVSWSPPAGDWEQYRILLWNDSSVLLNITVGKEETHYVIDDVGLIPGRRYEIEVTVESGNLKNSTRCQGRTVPLAVLHLRVKHANETSLSVMWQTPAAEWERYIVSLIDRDLLFIHKLLPRDAREFTFTNLVPGRKYIATVTSISGDLKNSSLTKGRTVPAQVTGLRVANQGTTNSLFTNWTQALGDVEFYQVLLIHENVVIKNESVSSETSGYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRSDYLSISWLPAPGDVDSYVVTLSHDGRVVQSLVIAKSVGECSFSSLTPGRLYNVTITTRSGKYESHSFSQERTVPNKVQGVSISNSARSDYLKVSWVHASGDFDHYEVTIKNKNNFIQTKSVPKSENECIFVKLVPGRLYSVTVSTKSGQYEASEQGNGRTIPEAVKDLTLKNRSTEDLWVTWTRADGDVDQYEIQLLFNDMKVFPPFHLVSTATEYRFTSLTPGRKYKILVLTISGDVQQSAFIEGFTVPSVVKNIHVSPSGATDSLTVNWTPGGGDVDSYVVSAFRQNQMVESQTVLKHISEHTFQRLEAGEQYRIVIASVSGSQKNQIDVLGRTIPASVQGITADNVYSSHSLIVSWQKAVGMAERYDILLLSENGILLSNTSEAATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTNLRITENSTRHLSFSWTPSEGELNSYNIFLYNPDRTLKDRALVDPQVQSFSFQNLLQGRMYRMVIVTHSGELSNESFIFGRTVPATVSNLKGSNQNMTDSLWFSWSPAPGDFDFYELILYNPNGTKKENWKDKDLTQWRFHGLVPGRKYTLCVITHSGDLSNKATGESRTEPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNKKDVLISKSSINFTFNCSWFSDTNGAVKYFTVVVREADGNDELKPEPQHPLPSYLEYRHNASIRVYQTDYFASKCAESPDSNSKSFNIKLGAEMESLGGKCDPNQQKFCDGPLKPRTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGVIEGVSAGLFLIGMLVAVVALFICRRKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKVNQFEGHFMKLQADSNYLLSKEYEDLKDVGRNQSCDIALLPENRGKNRYNNILPYDSSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFRICSEEQLDAHRLIRHFHYTVWPDHGVPESTQSLIQFVRTVRDYINRTPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDSGYSRH", "length": 1901, "header": "tr|A0ABI0NUX8-1|A0ABI0NUX8_BOVIN Computationally mapped isoform of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPRB PE=3 SV=1 CANONICAL=E1BFE2-1" }, "locus": { "chromosome": "5", "start_pos": 43010553, "end_pos": 42921020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150273.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150273.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107584.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107584.1" } ] } }, { "isoform_ac": "E1BFE2-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE2/entry#E1BFE2-1", "sequence": { "sequence": "MEAEFYMAILTCFIFVNSEGFQIVHVQKQQCLFKNGRVVMDLCNRTNQNQQWMWTEDGKLLHVKSALCLGISNSSGGPGRAAIFAPCSQAPRWTCYEKEGFLEVENASLFLKKQGVRVVVKKGRKYLHSWMKIDVNEEGKPVNESLCSKKAGPGTEVSVRSIRNTAPPQTPTTFNALPYSLGHLIRNTTEAFTRSTPENYSQNSSQSQHLSLWMAGMTSWVPWTTPPFSSTTEETGLGEPVRCNFTLTESRVSSRSVSLQWRTLAFPCNFNLTYSSDTSGVAWCHPVRIDNTTYGCNSEDLQAGTIYNFTIMSLDGEKKTMVLQTDPLPPARFEVSKEKTTTTSLHVWWTPSSGKVTWYEVQLLDDNQKIQTAQIQERASRNEYTFFNLTAGNKYNIAITAVSGDKRSSTMYANGSTVPSPVKDIGVLAKTNSLLISWSRGSGNVERYQLMLMDKGILVHSIAVDTTFYTFHGLTPGHLYNVTIVSEAAGLQNYKWKSARTTPMEVSNLKVTNEGTMTSLKVKWQRPSGNVDFYNITLSYQGTIKQSRTLASQITESQFKDLAPGRLYQVTVSCVSGELSAHRTAVGRTVPQKVGDLEANSNGSTKSLVVSWSPPAGDWEQYRILLWNDSSVLLNITVGKEETHYVIDDVGLIPGRRYEIEVTVESGNLKNSTRCQGRTVPLAVLHLRVKHANETSLSVMWQTPAAEWERYIVSLIDRDLLFIHKLLPRDAREFTFTNLVPGRKYIATVTSISGDLKNSSLTKGRTVPAQVTGLRVANQGTTNSLFTNWTQALGDVEFYQVLLIHENVVIKNESVSSETSGYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRSDYLSISWLPAPGDVDSYVVTLSHDGRVVQSLVIAKSVGECSFSSLTPGRLYNVTITTRSGKYESHSFSQERTVPNKVQGVSISNSARSDYLKVSWVHASGDFDHYEVTIKNKNNFIQTKSVPKSENECIFVKLVPGRLYSVTVSTKSGQYEASEQGNGRTIPEAVKDLTLKNRSTEDLWVTWTRADGDVDQYEIQLLFNDMKVFPPFHLVSTATEYRFTSLTPGRKYKILVLTISGDVQQSAFIEGFTVPSVVKNIHVSPSGATDSLTVNWTPGGGDVDSYVVSAFRQNQMVESQTVLKHISEHTFQRLEAGEQYRIVIASVSGSQKNQIDVLGRTIPASVQGITADNVYSSHSLIVSWQKAVGMAERYDILLLSENGILLSNTSEAATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTNLRITENSTRHLSFSWTPSEGELNSYNIFLYNPDRTLKDRALVDPQVQSFSFQNLLQGRMYRMVIVTHSGELSNESFIFGRTVPATVSNLKGSNQNMTDSLWFSWSPAPGDFDFYELILYNPNGTKKENWKDKDLTQWRFHGLVPGRKYTLCVITHSGDLSNKATGESRTAPSPPSLMSFADVTNTSLAITWKGPPDWTDYDDFELQWFPRDAITVFNPYSNRKSEGRIVHGLRPGRSYQFSVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNKKDVLISKSSINFTFNCSWFSDTNGAVKYFTVVVREADGNDELKPEPQHPLPSYLEYRHNASIRVYQTDYFASKCAESPDSNSKSFNIKLGAEMESLGGKCDPNQQKFCDGPLKPRTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGVIEGVSAGLFLIGMLVAVVALFICRRKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKVNQFEGHFMKLQADSNYLLSKEYEDLKDVGRNQSCDIALLPENRGKNRYNNILPYDSSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFRICSEEQLDAHRLIRHFHYTVWPDHGVPESTQSLIQFVRTVRDYINRTPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDSGYSRH", "length": 2211, "header": "tr|E1BFE2-1|E1BFE2_BOVIN Isoform 1 of protein-tyrosine-phosphatase OS=Bos taurus OX=9913 GN=PTPRB PE=3 SV=4 CANONICAL=E1BFE2-1" }, "locus": { "chromosome": "5", "start_pos": 43010553, "end_pos": 42885405, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020345.8", "url": "https://www.ensembl.org/id/ENSBTAT00000020345.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020345.7", "url": "https://www.ensembl.org/id/ENSBTAP00000020345.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2114, "start_aa": "Thr", "end_pos": 2114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2114", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:505696", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505696", "resource": "KEGG Pathway" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BFE2", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "E1BFE2", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "E1BFE2", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "E1BFE2", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "E1BFE2", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "E1BFE2", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "E1BFE2", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase inhibitor activity", "id": "GO:0030293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030293", "evidence": [ { "database": "UniProtKB", "id": "E1BFE2", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1043, "end_pos": 1045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1141, "end_pos": 1143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1254, "end_pos": 1256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1310, "end_pos": 1312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1377, "end_pos": 1379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1399, "end_pos": 1401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1426, "end_pos": 1428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1488, "end_pos": 1490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1581, "end_pos": 1583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1684, "end_pos": 1686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1688, "end_pos": 1690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1732, "end_pos": 1734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1930, "end_pos": 1932, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1973, "end_pos": 1975, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2106, "end_pos": 2108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 671, "end_pos": 673, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" }, { "start_pos": 788, "end_pos": 790, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 866, "end_pos": 868, "annotation": "n_glycosylation_sequon" }, { "start_pos": 923, "end_pos": 925, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1ME76-1", "F1MRH9-1", "A0AAF6DLF7-1", "A0AAA9S9Q3-1", "E1BFE2-1", "E1BL76-1", "G3MXS7-1", "A0A3Q1LUB1-1", "A0AAA9THG9-1", "F1N339-1", "F6RY99-1", "A0AAF6YUC8-1", "A0AAA9RTM1-1", "A0AAA9SMJ6-1", "A0A3Q1LZA9-1", "A7MBD1-1", "A5D7P0-1", "Q58DB6-1", "A0AAA9SEK4-1", "E1BDH9-1", "F1MGK4-1", "E1BIH4-1", "A0A3Q1M6K1-1", "E1BIU8-1", "A7MBJ4-1", "A6H730-1", "A0A3Q1MFX2-1", "A0AAA9U0H6-1", "A2VDT1-1", "E1BPU9-1", "P0C591-1", "P11064-1", "Q0IID7-1", "Q2KJ36-1", "Q2T9S4-1", "E1BPA0-1", "A0AAA9TAZ9-1", "Q5BIP9-1", "A0A3Q1M5K4-1", "F1MM08-1", "E1BJR7-1", "Q17QJ3-1", "Q17QM8-1", "F1MD22-1", "F1MI99-1", "F1MP34-1", "F1MGK5-1", "F1MEZ2-1", "F1MQM7-1", "E1BEZ8-1", "A0A3Q1M0B4-1", "A0AAA9S7W5-1", "A0A3Q1N8V6-1", "A0AAA9TFV5-1", "A0A3Q1MBB1-1", "F1MTZ3-1", "A0AAF6Z8C2-1", "F1MDF1-1", "A0AAA9T5N9-1", "E1BKT4-1", "A0A3Q1MH98-1", "F1N6L3-1", "F1MW70-1", "F1MXF2-1", "A0AAA9TWD1-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-BTA-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, tertiary granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q10741-1", "Q9MYM4-1", "Q05589-1", "Q08DI5-1", "F1MMX5-1", "Q27955-1", "A0A3Q1M9T8-1", "A0A3Q1LL74-1", "O46522-1", "E1BFE2-1" ], "evidence": [ { "id": "R-BTA-6798747", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798747" } ] }, { "id": "R-BTA-6799350", "name": "Exocytosis of specific granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, specific granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q10741-1", "Q3ZBY7-1", "A0A3Q1MGR4-1", "Q05589-1", "F1MLP3-1", "F1MMX5-1", "F1MQP2-1", "P62833-1", "Q1JPA0-1", "Q27955-1", "A0A3Q1M9T8-1", "A0A3Q1LL74-1", "A0ABI0P094-1", "A0AAA9SAV7-1", "A0A3Q1M6K1-1", "O46522-1", "E1BFE2-1" ], "evidence": [ { "id": "R-BTA-6799350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6799350" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LL74", "gene_name": "PLD1", "activity": [ { "ec_number": "3.1.4.4", "activity": "a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + ethanolamine + H(+).", "evidence": [ { "id": "A0A3Q1LL74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL74" } ] }, { "ec_number": "3.1.4.4", "activity": "", "evidence": [ { "id": "A0A3Q1LL74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL74" } ] } ] }, { "uniprot_ac": "A0A3Q1LUB1", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] } ] }, { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B4", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] } ] }, { "uniprot_ac": "A0A3Q1M5K4", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] } ] }, { "uniprot_ac": "A0A3Q1M6K1", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] } ] }, { "uniprot_ac": "A0A3Q1M9T8", "gene_name": "ATP11A", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A3Q1M9T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9T8" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A3Q1M9T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9T8" } ] } ] }, { "uniprot_ac": "A0A3Q1MBB1", "gene_name": "TNS2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] } ] }, { "uniprot_ac": "A0A3Q1MFX2", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] } ] }, { "uniprot_ac": "A0A3Q1MGR4", "gene_name": "RAB37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1N8V6", "gene_name": "LOC101903026", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S7W5", "gene_name": "PTPRV", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] } ] }, { "uniprot_ac": "A0AAA9S9Q3", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] } ] }, { "uniprot_ac": "A0AAA9SAV7", "gene_name": "AGPAT2", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0AAA9SAV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAV7" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0AAA9SAV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAV7" } ] } ] }, { "uniprot_ac": "A0AAA9SEK4", "gene_name": "PTPRE", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] } ] }, { "uniprot_ac": "A0AAA9SMJ6", "gene_name": "PTPRH", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] } ] }, { "uniprot_ac": "A0AAA9T5N9", "gene_name": "", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] } ] }, { "uniprot_ac": "A0AAA9TAZ9", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] } ] }, { "uniprot_ac": "A0AAA9TFV5", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] } ] }, { "uniprot_ac": "A0AAA9THG9", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] } ] }, { "uniprot_ac": "A0AAA9TWD1", "gene_name": "PTPN20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YUC8", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] } ] }, { "uniprot_ac": "A0AAF6Z8C2", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] } ] }, { "uniprot_ac": "A0ABI0P094", "gene_name": "HMOX2", "activity": [ { "ec_number": "1.14.14.18", "activity": "heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe(2+) + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+).", "evidence": [ { "id": "A0ABI0P094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ] }, { "ec_number": "1.14.14.18", "activity": "", "evidence": [ { "id": "A0ABI0P094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ] } ] }, { "uniprot_ac": "A2VDT1", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] } ] }, { "uniprot_ac": "A5D7P0", "gene_name": "CDC25C", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] } ] }, { "uniprot_ac": "A6H730", "gene_name": "ACP3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] } ] }, { "uniprot_ac": "A7MBD1", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] } ] }, { "uniprot_ac": "A7MBJ4", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] } ] }, { "uniprot_ac": "E1BDH9", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] } ] }, { "uniprot_ac": "E1BEZ8", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] } ] }, { "uniprot_ac": "E1BFE2", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] } ] }, { "uniprot_ac": "E1BIH4", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] } ] }, { "uniprot_ac": "E1BIU8", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] } ] }, { "uniprot_ac": "E1BJR7", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] } ] }, { "uniprot_ac": "E1BKT4", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] } ] }, { "uniprot_ac": "E1BL76", "gene_name": "CDC25B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] } ] }, { "uniprot_ac": "E1BPA0", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] } ] }, { "uniprot_ac": "E1BPU9", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] } ] }, { "uniprot_ac": "F1MD22", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] } ] }, { "uniprot_ac": "F1MDF1", "gene_name": "PTPN18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MGK4", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] } ] }, { "uniprot_ac": "F1MGK5", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MLP3", "gene_name": "BST1", "activity": [ { "ec_number": "3.2.2.6", "activity": "NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+).", "evidence": [ { "id": "F1MLP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLP3" } ] }, { "ec_number": "3.2.2.6", "activity": "", "evidence": [ { "id": "F1MLP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLP3" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MMX5", "gene_name": "ATP8B4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MMX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMX5" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MMX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMX5" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MQP2", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] } ] }, { "uniprot_ac": "F1MRH9", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] } ] }, { "uniprot_ac": "F1MTZ3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1MXF2", "gene_name": "MDP1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] } ] }, { "uniprot_ac": "F1N339", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] } ] }, { "uniprot_ac": "F1N6L3", "gene_name": "PTPN22", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6L3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6L3" } ] } ] }, { "uniprot_ac": "F6RY99", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F6RY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F6RY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ] } ] }, { "uniprot_ac": "G3MXS7", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ] } ] }, { "uniprot_ac": "O46522", "gene_name": "CYBB", "activity": [ { "ec_number": "1.6.3.-", "activity": "", "evidence": [ { "id": "O46522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46522" } ] } ] }, { "uniprot_ac": "P0C591", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] } ] }, { "uniprot_ac": "P11064", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] } ] }, { "uniprot_ac": "P62833", "gene_name": "RAP1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P62833", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62833" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P62833", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62833" } ] } ] }, { "uniprot_ac": "Q05589", "gene_name": "PLAU", "activity": [ { "ec_number": "3.4.21.73", "activity": "Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.", "evidence": [ { "id": "Q05589", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05589" } ] }, { "ec_number": "3.4.21.73", "activity": "", "evidence": [ { "id": "Q05589", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05589" } ] } ] }, { "uniprot_ac": "Q08DI5", "gene_name": "RAP2C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q08DI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DI5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q08DI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DI5" } ] } ] }, { "uniprot_ac": "Q0IID7", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] } ] }, { "uniprot_ac": "Q10741", "gene_name": "ADAM10", "activity": [ { "ec_number": "3.4.24.81", "activity": "Endopeptidase of broad specificity.", "evidence": [ { "id": "Q10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q10741" } ] }, { "ec_number": "3.4.24.81", "activity": "", "evidence": [ { "id": "Q10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q10741" } ] } ] }, { "uniprot_ac": "Q17QJ3", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] } ] }, { "uniprot_ac": "Q17QM8", "gene_name": "DUSP14", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] } ] }, { "uniprot_ac": "Q1JPA0", "gene_name": "ALDH3B1", "activity": [ { "ec_number": "1.2.1.5", "activity": "an aldehyde + NADP(+) + H2O = a carboxylate + NADPH + 2 H(+).", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.28", "activity": "benzaldehyde + NAD(+) + H2O = benzoate + NADH + 2 H(+).", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.7", "activity": "benzaldehyde + NADP(+) + H2O = benzoate + NADPH + 2 H(+).", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.48", "activity": "a long-chain fatty aldehyde + NAD(+) + H2O = a long-chain fatty acid + NADH + 2 H(+).", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.5", "activity": "", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.7", "activity": "", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.28", "activity": "", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] } ] }, { "uniprot_ac": "Q27955", "gene_name": "KCNAB2", "activity": [ { "ec_number": "1.1.1.-", "activity": "", "evidence": [ { "id": "Q27955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27955" } ] } ] }, { "uniprot_ac": "Q2KJ36", "gene_name": "DUSP6", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] } ] }, { "uniprot_ac": "Q2T9S4", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] }, { "ec_number": "3.1.3.18", "activity": "2-phosphoglycolate + H2O = glycolate + phosphate.", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] }, { "ec_number": "3.1.3.18", "activity": "", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] } ] }, { "uniprot_ac": "Q3ZBY7", "gene_name": "DEGS1", "activity": [ { "ec_number": "1.14.19.17", "activity": "an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O.", "evidence": [ { "id": "Q3ZBY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBY7" } ] }, { "ec_number": "5.2.1.-", "activity": "", "evidence": [ { "id": "Q3ZBY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBY7" } ] }, { "ec_number": "1.14.19.17", "activity": "", "evidence": [ { "id": "Q3ZBY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBY7" } ] } ] }, { "uniprot_ac": "Q58DB6", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q58DB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DB6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q58DB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DB6" } ] } ] }, { "uniprot_ac": "Q5BIP9", "gene_name": "DUSP18", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.48", "activity": 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"biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 329, "end_pos": 421, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 2092, "end_pos": 2168, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": 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Permeable to bicarbonate.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9RYU8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYU8#function" }, { "database": "UniProtKB", "id": "RU363126", "url": "https://www.uniprot.org/uniprotkb/RU363126#function" }, { "database": "UniProtKB", "id": "A0AAA9SHT8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHT8#function" }, { "database": "UniProtKB", "id": "A0AAA9SE59", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE59#function" }, { "database": "UniProtKB", "id": "E1BF90", "url": "https://www.uniprot.org/uniprotkb/E1BF90#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BF90", "url": "https://www.uniprot.org/uniprotkb/E1BF90" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BEST3", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SE59", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SE59-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SHT8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SHT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF90", "url": "https://www.uniprot.org/uniprotkb/E1BF90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF90-1", "url": "https://www.uniprot.org/uniprotkb/E1BF90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLMYRLLLTGAQKRFFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTADERKLFDHLKSPHLKYWVPFIWFGNLAAKARKEGRIRDSVDLQSLMTEMNRFRSWCSLLFGYDWVGIPLVYTQVVTLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPVFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLGSTVQMGLSGSDLPGDEWLWDFEKHGHRRSVIRRVKRFLSAHEHAASSPRRRSYGRQASDSSMFFPPRDLSPTRDLLDVPPTSPHRASAPRKHPQSPKGSPKLHSSLGELSTIQETSLSPQSSVRGSPTKMPQVAEVLVTATKALAPAAEHDRRDSTASIQSSDFTGLQPSRPGQQEDPVGSIPFSFKKGMPPRDPRSQAVPAKAEKNSLKSASEEDPHRRTSPPRLPDSSHTSLAGLSLDPMNPEPLPLLDPETSSETSGITFAAGSRVSPDVLYLIENLDTKETDIVEFNNEQTEESPKG", "length": 662, "header": "tr|E1BF90-1|E1BF90_BOVIN Isoform 1 of Bestrophin OS=Bos taurus OX=9913 GN=BEST3 PE=3 SV=4 CANONICAL=E1BF90-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RYU8-1", "url": "https://www.uniprot.org/uniprotkb/E1BF90/entry#A0AAA9RYU8-1", "sequence": { "sequence": 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"ENSBTAP00000076317.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076317.1" } ] } }, { "isoform_ac": "A0AAA9SE59-1", "url": "https://www.uniprot.org/uniprotkb/E1BF90/entry#A0AAA9SE59-1", "sequence": { "sequence": "MFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAERIGNKLKSFEKQSS", "length": 69, "header": "tr|A0AAA9SE59-1|E1BF90_BOVIN Computationally mapped isoform of Bestrophin OS=Bos taurus OX=9913 GN=BEST3 PE=3 SV=1 CANONICAL=E1BF90-1" }, "locus": { "chromosome": "5", "start_pos": 43776825, "end_pos": 43768660, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134701.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134701.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081873.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081873.1" } ] } }, { "isoform_ac": "A0AAA9SHT8-1", "url": "https://www.uniprot.org/uniprotkb/E1BF90/entry#A0AAA9SHT8-1", "sequence": { "sequence": "MFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTADERKLFDHLKSPHLKYWVPFIWFGNLAAKARKEGRIRDSVDLQSLMTEMNRFRSWCSLLFGYDWVGIPLVYTQVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLGSTVQMGLSGSDLPGDEWLWDFEKHGHRRSVIRRVKRFLSAHEHAASSPRRRSYGRQASDSSMFFPPRDLSPTRDLLDVPPTSPHRASAPRKHPQSPKGSPKLHSSLGELSTIQETSLSPQSSVRGSPTKMPQVAEVLVTATKALAPAAEHDRRDSTASIQSSDFTGLQPSRPGQQEDPVGSIPFSFKKGMPPRDPRSQAVPAKAEKNSLKSASEEDPHRRTSPPRLPDSSHTSLAGLSLDPMNPEPLPLLDPETSSETSGITFAAGSRVSPDVLYLIENLDTKETDIVEFNNEQTEESPKG", "length": 505, "header": "tr|A0AAA9SHT8-1|E1BF90_BOVIN Computationally mapped isoform of Bestrophin OS=Bos taurus OX=9913 GN=BEST3 PE=3 SV=1 CANONICAL=E1BF90-1" }, "locus": { "chromosome": "5", "start_pos": 43817030, "end_pos": 43768660, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105898.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105898.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084907.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084907.1" } ] } }, { "isoform_ac": "E1BF90-1", "url": "https://www.uniprot.org/uniprotkb/E1BF90/entry#E1BF90-1", "sequence": { "sequence": "MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLMYRLLLTGAQKRFFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTADERKLFDHLKSPHLKYWVPFIWFGNLAAKARKEGRIRDSVDLQSLMTEMNRFRSWCSLLFGYDWVGIPLVYTQVVTLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPVFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLGSTVQMGLSGSDLPGDEWLWDFEKHGHRRSVIRRVKRFLSAHEHAASSPRRRSYGRQASDSSMFFPPRDLSPTRDLLDVPPTSPHRASAPRKHPQSPKGSPKLHSSLGELSTIQETSLSPQSSVRGSPTKMPQVAEVLVTATKALAPAAEHDRRDSTASIQSSDFTGLQPSRPGQQEDPVGSIPFSFKKGMPPRDPRSQAVPAKAEKNSLKSASEEDPHRRTSPPRLPDSSHTSLAGLSLDPMNPEPLPLLDPETSSETSGITFAAGSRVSPDVLYLIENLDTKETDIVEFNNEQTEESPKG", "length": 662, "header": "tr|E1BF90-1|E1BF90_BOVIN Isoform 1 of Bestrophin OS=Bos taurus OX=9913 GN=BEST3 PE=3 SV=4 CANONICAL=E1BF90-1" }, "locus": { 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"url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] }, { "uniprot_ac": "Q5E9B7", "gene_name": "CLIC1", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "Q5E9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B7" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "Q5E9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B7" } ] } ] }, { "uniprot_ac": "Q9XSA7", "gene_name": "CLIC4", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "Q9XSA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XSA7" } ] } ] } ], "biomarkers": [], "structures": [ { 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"MASLNVSLCFFLATFALCQASRRAAKALLPGGAYAHFAREAAGAAQLGACCLEMRMLVELGPWAGGFGPDLLLTLVFLLLLVHGATLDGASANPTVSLQRFLLAEASLPCTLLELAAQALGVQAAGALTRLYWAWGLSDLHVLQSLMDPHCSSALRTAVPHGALLEGSCAFLLHLVLLRLQGSLAIHRVLAVALLLTAAACTAGPLTSAFLNPALAASVTFRCSGHSLLEYVQVYWLGPVTGMLLAVLLYHGRLPRLFQRNLLYSQKSKYRVPRGRPVPGPGGSQTPEEGSRGRGPGSGGQPLSSSH", "length": 307, "header": "tr|E1BDW5-1|E1BDW5_BOVIN Isoform 1 of Aquaporin OS=Bos taurus OX=9913 GN=AQP12 PE=3 SV=4 CANONICAL=E1BDW5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S0F9-1", "url": "https://www.uniprot.org/uniprotkb/E1BDW5/entry#A0AAA9S0F9-1", "sequence": { "sequence": "MASLNVSLCFFLATFALCQASRRAAKALLPGGAYAHFAREAMRMLVELGPWAGGFGPDLLLTLVFLLLLVHGATLDGASANPTVSLQRFLLAEASLPCTLLELAAQALGVQAAGALTRLYWAWGLSDLHVLQSLMDPHCSSALRTAVPHGALLEGSCAFLLHLVLLRLQGSLAIHRVLAVALLLTAAACTAGPLTSAFLNPALAASVTFRCSGHSLLEYVQVYWLGPVTGMLLAVLLYHGRLPRLFQRNLLYSQKSKYRVPRGRPVPGPGGSQTPEEGSRGRGPGSGGQPLSSSH", "length": 295, "header": "tr|A0AAA9S0F9-1|E1BDW5_BOVIN Computationally mapped isoform of Aquaporin OS=Bos taurus OX=9913 GN=AQP12 PE=3 SV=1 CANONICAL=E1BDW5-1" }, "locus": { "chromosome": "3", "start_pos": 120028930, "end_pos": 120025839, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090991.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090991.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079331.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079331.1" } ] } }, { "isoform_ac": "E1BDW5-1", "url": "https://www.uniprot.org/uniprotkb/E1BDW5/entry#E1BDW5-1", "sequence": { "sequence": "MASLNVSLCFFLATFALCQASRRAAKALLPGGAYAHFAREAAGAAQLGACCLEMRMLVELGPWAGGFGPDLLLTLVFLLLLVHGATLDGASANPTVSLQRFLLAEASLPCTLLELAAQALGVQAAGALTRLYWAWGLSDLHVLQSLMDPHCSSALRTAVPHGALLEGSCAFLLHLVLLRLQGSLAIHRVLAVALLLTAAACTAGPLTSAFLNPALAASVTFRCSGHSLLEYVQVYWLGPVTGMLLAVLLYHGRLPRLFQRNLLYSQKSKYRVPRGRPVPGPGGSQTPEEGSRGRGPGSGGQPLSSSH", "length": 307, "header": "tr|E1BDW5-1|E1BDW5_BOVIN Isoform 1 of Aquaporin OS=Bos taurus OX=9913 GN=AQP12 PE=3 SV=4 CANONICAL=E1BDW5-1" }, "locus": { "chromosome": "3", "start_pos": 120028930, "end_pos": 120025839, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004395.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004395.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004395.7", "url": "https://www.ensembl.org/id/ENSBTAP00000004395.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-432047", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432047", "resource": "Reactome", "description": "Passive transport by Aquaporins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BDW5", "url": "https://www.uniprot.org/uniprotkb/E1BDW5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BDW5", "url": "https://www.uniprot.org/uniprotkb/E1BDW5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "channel activity", "id": "GO:0015267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015267", "evidence": [ { "database": "UniProtKB", "id": "E1BDW5", "url": "https://www.uniprot.org/uniprotkb/E1BDW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDW5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 307, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDW5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDW5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJK1-1", "uniprot_ac": "E1BJK1", "uniprot_id": "E1BJK1_BOVIN", "mass": { "chemical_mass": 70442.0, "monoisotopic_mass": 70442.0 }, "refseq": {}, "gene_names": [ { "name": "ZDHHC17", "type": "recommended", "evidence": [ { "id": "E1BJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "E1BJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJK1/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "E1BJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJK1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZDHHC17", "url": "https://www.uniprot.org/uniprotkb/E1BJK1", "locus": { "chromosome": "5", "start_pos": 6292754, "end_pos": 6174646, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021756", "url": "https://www.ensembl.org/id/ENSBTAG00000021756" } ] } } ], "crossref": [ { "id": "E1BJK1", "url": "https://alphafold.ebi.ac.uk/entry/E1BJK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021756", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021756", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "541172", "url": "https://www.ncbi.nlm.nih.gov/gene/541172", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541172", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541172", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FWVGFRY", "url": "https://omabrowser.org/oma/group/FWVGFRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LTI4", "url": "https://www.orthodb.org/?gene=A0A3Q1LTI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BJK1", "url": "https://www.orthodb.org/?gene=E1BJK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24161:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24161:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LTI4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3B4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3B4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3B4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKJ7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T511", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T511", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T511-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T511-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJK1-1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQREEGFNTKMADGPDEYESEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSIALFYNFGKSWKSDPGIIKATEEQKKKIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETSYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV", "length": 611, "header": "tr|E1BJK1-1|E1BJK1_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC17 PE=3 SV=3 CANONICAL=E1BJK1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LTI4-1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1/entry#A0A3Q1LTI4-1", "sequence": { "sequence": "MQREEGFNTKMADGPDEYESEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSIALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETSYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFKATRDF", "length": 592, "header": "tr|A0A3Q1LTI4-1|E1BJK1_BOVIN Computationally mapped isoform of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC17 PE=3 SV=2 CANONICAL=E1BJK1-1" }, "locus": { "chromosome": "5", "start_pos": 6292647, "end_pos": 6174845, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067589.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067589.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060637.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060637.2" } ] } }, { "isoform_ac": "A0AAA9S3B4-1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1/entry#A0AAA9S3B4-1", "sequence": { "sequence": "MSIFPEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNAHLNFLFIHLPFLANSIALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETSYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV", "length": 607, "header": "tr|A0AAA9S3B4-1|E1BJK1_BOVIN Computationally mapped isoform of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC17 PE=3 SV=2 CANONICAL=E1BJK1-1" }, "locus": { "chromosome": "5", "start_pos": 6272507, "end_pos": 6175640, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098243.2", "url": "https://www.ensembl.org/id/ENSBTAT00000098243.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076588.2", "url": "https://www.ensembl.org/id/ENSBTAP00000076588.2" } ] } }, { "isoform_ac": "A0AAA9SKJ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1/entry#A0AAA9SKJ7-1", "sequence": { "sequence": "MQREEGFNTKMADGPDEYESEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSIALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETSYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQSNSGLLKKEEYPPFSYAIQGYINSLLISQV", "length": 585, "header": "tr|A0AAA9SKJ7-1|E1BJK1_BOVIN Computationally mapped isoform of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC17 PE=3 SV=1 CANONICAL=E1BJK1-1" }, "locus": { "chromosome": "5", "start_pos": 6292721, "end_pos": 6174845, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128331.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128331.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084437.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084437.1" } ] } }, { "isoform_ac": "A0AAA9T511-1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1/entry#A0AAA9T511-1", "sequence": { "sequence": "MQREEGFNTKMADGPDEYESEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSIALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVDWGLHCETSYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV", "length": 604, "header": "tr|A0AAA9T511-1|E1BJK1_BOVIN Computationally mapped isoform of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC17 PE=3 SV=1 CANONICAL=E1BJK1-1" }, "locus": { "chromosome": "5", "start_pos": 6272507, "end_pos": 6174845, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096432.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096432.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092910.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092910.1" } ] } }, { "isoform_ac": "E1BJK1-1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1/entry#E1BJK1-1", "sequence": { "sequence": "MQREEGFNTKMADGPDEYESEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSIALFYNFGKSWKSDPGIIKATEEQKKKIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETSYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV", "length": 611, "header": "tr|E1BJK1-1|E1BJK1_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC17 PE=3 SV=3 CANONICAL=E1BJK1-1" }, "locus": { "chromosome": "5", "start_pos": 6272507, "end_pos": 6174845, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028999.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028999.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028999.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028999.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:541172", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541172", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YMN9-1", "protein_name": "Palmitoyltransferase", "gene_name": "ZDHHC17", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTAVSCIQGLWCFSPALHSASHQEIKPQSHYNHGYSESLGRKSHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESPLDLAKQRKNVWMINHLQEARQAKGYDSPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGLMYGGVWAMVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFFFIHLPFLANSIALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGFHCETSYAKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCIRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQTSGSGYQLV", "length": 624 }, "evidence": [ { "id": "E1BJK1", "url": "https://omabrowser.org/oma/group/E1BJK1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A5WVX9-1", "protein_name": "Palmitoyltransferase ZDHHC17", "gene_name": "zdhhc17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADALVGYEKEAGCVPILHPEEIKPQSHYNHGYNESRKSHVDDYSTWDIVKATQYGIFERCRELVEAGYDVRQPDKENVTLLHWAAINNRVDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCVHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEANANVDAQNIKGETPLDLAKQRKNVWMINHLQEARQAKGYDSPSYLKRLKMDKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGVMYAVMWLVVQFLSKSFFDHSMHSALPLGIYLATKFWMYITWFYWFWNDLPFVTIHLPFLLNSLALFYNFGKSWKSDPGIIKASEEQKKKTIVELAETGSLDLSIFCSTCLIRKPIRSKHCAVCNRCIAKFDHHCPWVGNCVGSGNHRYFMGYLFFLLCMICWMMYGCICYWRIHCATSYTKDGFWIYITQIATCSPWMFWMFLNSVFHFMWVAVLIMCQLYQIAVLGITTNERMNARRYKHFKVTATSIESPFNHGCMRNLIDFFELRCCGLLRPVPIDWTSQYTIEYDQTSGSGYQLV", "length": 620 }, "evidence": [ { "id": "E1BJK1", "url": "https://omabrowser.org/oma/group/E1BJK1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PTT0-1", "protein_name": "Palmitoyltransferase ZDHHC17", "gene_name": "Zdhhc17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADGPDEYDTETGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHVDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLSFLSIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCVSYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQITCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV", "length": 622 }, "evidence": [ { "id": "E1BJK1", "url": "https://omabrowser.org/oma/group/E1BJK1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P39010-1", "protein_name": "Palmitoyltransferase AKR1", "gene_name": "AKR1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVNELENVPRASTLTNEEQTVDPSNNDSQEDISLGDSNEITSLASLKAIRSGNEEESGNEQVNHNDEAEEDPLLTRYHTACQRGDLATVKEMIHGKLLEVNNDGDSTEHITGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIAQEMNTVYSLREALTHSGFDYHGYPIKKWFKKSQHAKLVTFITPFLFLGIAFALFSHINPLFVIIVLFLLAIATNKGLNKFVLPSYGRMGVHNVTLLRSPLLSGVFFGTLLWVTIVWFFKVMPRTFSDEQYTNILMLVILVSVFYLFGQLVIMDPGCLPEETDHENVRQTISNLLEIGKFDTKNFCIETWIRKPLRSKFSPLNNAVVARFDHYCPWIFNDVGLKNHKAFIFFITLMESGIFTFLALCLEYFDELEDAHEDTSQKNGKCFILGASDLCSGLIYDRFVFLILLWALLQSIWVASLIFVQAFQICKGMTNTEFNVLMKESKSIGPDGLSFNENFNTTPEGFAPSIDPGEESNDTVLAPVPGSTIRKPRTCFGVCYAVTGMDQWLAVIKETIGIKDSTGHNVYSITSRIPTNYGWKRNVKDFWLTSDINAPLWRRILYPPSGSKALLNGIEVDYFKLYKLPNKDVEQGNDMV", "length": 764 }, "evidence": [ { "id": "E1BJK1", "url": "https://omabrowser.org/oma/group/E1BJK1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3EC11-1", "protein_name": "Probable protein S-acyltransferase 23", "gene_name": "PAT23", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSEIEVVPLDSNSHQSPTESPTITDVFSASAYGDLHQLKHFVEHNGSSVSLPDDNGFYALQWAALNNSLHVAQYIIQHGGDVNSADNIQQTPLHWAAVKGSIDVADLLLQHGARIEAVDVNGFRAVHVASQYGQTAFVNHIIVDYAADYNALDIEGRSPLHWAAYNGFTETVRLLLFRDACQNRQDNTGCTPLHWAVIKENVEACTLLVHAGTKEELILKDNTGSTPLKLASDKGHRQLALFLSKAMRTRKNSFVDKIFCGKLGETSYAPMLFSLIVILMVLFITSIVSASNLPKITAMVGLWACFGLSCGVYALITFYRVSRKDPGYVKRTGEANSQHTANDPLIDINFKNPSWKGNWSQLCPTCKIIRPVRSKHCPTCKRCVEQFDHHCPWISNCVGKKNKRYFLVFVIMGALTSFVGGTTAVQRLWRGIPQVHHGESWIKHIVIEHPDAAVFLFFDLLIFIATMTLTISQSYMIARNITTNELWNAKRFSYLRGPDGRFYNPYNHGLRRNCTDFLVHGYTRDDEVVPSSIL", "length": 536 }, "evidence": [ { "id": "E1BJK1", "url": "https://omabrowser.org/oma/group/E1BJK1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q80TN5-1", "protein_name": "Palmitoyltransferase ZDHHC17", "gene_name": "Zdhhc17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREEGFNTKMADGPDEYETETGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCVSYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFLWVAVLLMCQLYQITCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV", "length": 632 }, "evidence": [ { "id": "E1BJK1", "url": "https://omabrowser.org/oma/group/E1BJK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IUH5-1", "protein_name": "Palmitoyltransferase ZDHHC17", "gene_name": "ZDHHC17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQREEGFNTKMADGPDEYDTEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV", "length": 632 }, "evidence": [ { "id": "E1BJK1", "url": "https://omabrowser.org/oma/group/E1BJK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VUW9-1", "protein_name": "Palmitoyltransferase Hip14", "gene_name": "Hip14", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYQSACQAATTGSCVPGTGQQPDNERQSALIAQQPPTAPVEPDYSGFDIVKATQYGAIARVRELVESGWDVNQPDSETVTLLHWAAINNRRDIIRYFLEKGATVDAVGGELNATPLHWATRQGHLGAVVLLMAAGADPRIRDAEGCSCIHIAAQFAHTALVAYFIAKGVDPDLQDRGGMTALMWAAWKVCALDPVRLLLTLGANPAMVDYTHGNTALHWAILARNATAISTLVLKSKASLDVPNLRGETPLSMLESQTGAIWIGAKVMDRVKEAALTSQQRRSLLSKLRHDKRLRWWSMVACPFTAFYLAGIVFTVNTLYIIKFFLLGCLYSIFHTIGKALFDEHLMALLPLSVYLATKAWFYVTWLMYIDDAVSFTATVCFLISSLLLWVCFLKSWKGDPGIIRPTREQRFKTIIELSERGGIGFEPASFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAWMLYGGSKYYVNQCNVRFDDFLGAMRAIGNCDAWVGWVMGNALLHMSWVILLTICQTYQVICLGMTTNERMNRGRYRHFQAKGGHSPFTRGPIQNLVDFLECSCFGLVQPKRVDWMNYYDYDAQTHQTIEKEPLLSVDCPDGMAGDHQYV", "length": 637 }, "evidence": [ { "id": "E1BJK1", "url": "https://omabrowser.org/oma/group/E1BJK1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "Golgi-associated vesicle membrane", "id": "GO:0030660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030660", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "postsynaptic Golgi apparatus", "id": "GO:0150051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150051", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "perforant pathway to dendrate granule cell synapse", "id": "GO:0140240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140240", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "lipoprotein transport", "id": "GO:0042953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042953", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "regulation of ERK1 and ERK2 cascade", "id": "GO:0070372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070372", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "regulation of programmed cell death", "id": "GO:0043067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043067", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "regulation of neurotrophin TRK receptor signaling pathway", "id": "GO:0051386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051386", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" }, { "name": "regulation of modification of synapse structure, modulating synaptic transmission", "id": "GO:0098987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098987", "evidence": [ { "database": "UniProtKB", "id": "E1BJK1", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3X756-1", "E1BPA5-1", "F1MVC6-1", "E1B987-1", "E1BJK1-1", "F6R785-1", "A0AAA9TDW4-1", "A0AAA9TVJ9-1", "A0AAA9TM40-1", "E1B6X9-1", "E1BKA0-1", "E1BK60-1", "Q58CU4-1", "A2VDT6-1", "A0AAF6ZH94-1", "A0AAA9RZ07-1", "Q0VC89-1", "E1BLT8-1", "G3MXF3-1", "P15103-1", "Q2HJ95-1", "Q58DA8-1", "A0A3Q1M794-1", "A0A3Q1LVW6-1", "Q58DT3-1", "A0A3Q1M403-1", "A0ABI0NXA5-1" ], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LVW6", "gene_name": "ZDHHC13", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1LVW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVW6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1LVW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVW6" } ] } ] }, { "uniprot_ac": "A0A3Q1M403", "gene_name": "", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] } ] }, { "uniprot_ac": "A0A3Q1M794", "gene_name": "ZDHHC3", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M794", "database": "UniProtKB", "url": 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"evidence": [ { "id": "E1BIM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BIM7", "locus": {} } ], "crossref": [ { "id": "E1BIM7", "url": "https://alphafold.ebi.ac.uk/entry/E1BIM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008937", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008937", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12631", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12631", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12634", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12634", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12638", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12638", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034196", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034196", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034199", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034199", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LVI7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MSL2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MSL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S544", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S544", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S544-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S544-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5H7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5H7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5H7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIM7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCPKSAVTMRNEELLLSNGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATTTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAVAQMLSGMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 514, "header": "tr|E1BIM7-1|E1BIM7_BOVIN Isoform 1 of CUGBP Elav-like family member 2 OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=E1BIM7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVI7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM7/entry#A0A3Q1LVI7-1", "sequence": { "sequence": "MKQSNGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATTTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAGTINSMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 498, "header": "tr|A0A3Q1LVI7-1|E1BIM7_BOVIN Computationally mapped isoform of CUGBP Elav-like family member 2 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BIM7-1" }, "locus": { "chromosome": "13", "start_pos": 13293295, "end_pos": 12875378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080578.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080578.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064648.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064648.2" } ] } }, { "isoform_ac": "A0A3Q1MSL2-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM7/entry#A0A3Q1MSL2-1", "sequence": { "sequence": "MTSAFKLDFLPDMMVEGRLLVPDRINGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATTTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAGTINTISRRLLFESPSMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 530, "header": "tr|A0A3Q1MSL2-1|E1BIM7_BOVIN Computationally mapped isoform of CUGBP Elav-like family member 2 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BIM7-1" }, "locus": { "chromosome": "13", "start_pos": 13184680, "end_pos": 12875378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067211.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067211.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057512.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057512.2" } ] } }, { "isoform_ac": "A0AAA9S544-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM7/entry#A0AAA9S544-1", "sequence": { "sequence": "MTSAFKLDFLPDMMVEGRLLVPDRINGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATTTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAGTINSMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 471, "header": "tr|A0AAA9S544-1|E1BIM7_BOVIN Computationally mapped isoform of CUGBP Elav-like family member 2 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=E1BIM7-1" }, "locus": { "chromosome": "13", "start_pos": 13184680, "end_pos": 12875378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109542.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109542.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080302.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080302.1" } ] } }, { "isoform_ac": "A0AAA9S5H7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM7/entry#A0AAA9S5H7-1", "sequence": { "sequence": "MSWLGVRPARSTVLAFHPLGVEASGNPRGAPHFQVRSNGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATTTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAGTINSMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 531, "header": "tr|A0AAA9S5H7-1|E1BIM7_BOVIN Computationally mapped isoform of CUGBP Elav-like family member 2 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=E1BIM7-1" }, "locus": { "chromosome": "13", "start_pos": 13189242, "end_pos": 12875378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101249.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101249.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080467.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080467.1" } ] } }, { "isoform_ac": "A0AAA9SZV1-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM7/entry#A0AAA9SZV1-1", "sequence": { "sequence": "MRETTTELAGSLPSNGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATTTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAGMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 504, "header": "tr|A0AAA9SZV1-1|E1BIM7_BOVIN Computationally mapped isoform of CUGBP Elav-like family member 2 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=E1BIM7-1" }, "locus": { "chromosome": "13", "start_pos": 13305219, "end_pos": 12875378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124842.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124842.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092007.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092007.1" } ] } }, { "isoform_ac": "E1BIM7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM7/entry#E1BIM7-1", "sequence": { "sequence": "MRCPKSAVTMRNEELLLSNGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATTTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAVAQMLSGMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 514, "header": "tr|E1BIM7-1|E1BIM7_BOVIN Isoform 1 of CUGBP Elav-like family member 2 OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=E1BIM7-1" }, "locus": { "chromosome": "13", "start_pos": 13197352, "end_pos": 12875378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011768.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011768.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011768.7", "url": "https://www.ensembl.org/id/ENSBTAP00000011768.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" } ], "pmid": "" }, { "name": "lncRNA binding", "id": "GO:0106222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106222", "evidence": [ { "database": "UniProtKB", "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" } ], "pmid": "" }, { "name": "mRNA splice site recognition", "id": "GO:0006376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006376", "evidence": [ { "database": "UniProtKB", "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "E1BIM7", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM7" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 123, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 467, "end_pos": 469 }, { "start_pos": 509, "end_pos": 511 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJH8-1", "uniprot_ac": "E1BJH8", "uniprot_id": "E1BJH8_BOVIN", "mass": { "chemical_mass": 71602.0, "monoisotopic_mass": 71602.0 }, "refseq": {}, "gene_names": [ { "name": "MTMR6", "type": "recommended", "evidence": [ { "id": "E1BJH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH8" } ] } ], "protein_names": [ { "name": "Myotubularin related protein 6", "type": "synonym", "evidence": [ { "id": "E1BJH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJH8", "url": "https://www.uniprot.org/uniprotkb/E1BJH8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MTMR6", "url": "https://www.uniprot.org/uniprotkb/E1BJH8", "locus": { "chromosome": "12", "start_pos": 33969469, "end_pos": 33932187, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003116", "url": "https://www.ensembl.org/id/ENSBTAG00000003116" } ] } } ], "crossref": [ { "id": "E1BJH8", "url": "https://alphafold.ebi.ac.uk/entry/E1BJH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003116", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003116", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13343", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13343", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14585", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14585", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540589", "url": "https://www.ncbi.nlm.nih.gov/gene/540589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QWQHTDV", "url": "https://omabrowser.org/oma/group/QWQHTDV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LYK5", "url": "https://www.orthodb.org/?gene=A0A3Q1LYK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BJH8", "url": "https://www.orthodb.org/?gene=E1BJH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LYK5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5S3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5S3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJH8", "url": "https://www.uniprot.org/uniprotkb/E1BJH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BJH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDAHQKETWILHHHIASVEKLALTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDAERLRGWELIDLAEEYKRMGVPNSNWQLSDANREYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQSKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPANRYMYVMDTRPRLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAVMDAAIFLAKAIAAESASVLVHCSDGWDRTSQVCSLGSLLLDPYYRTIRGFMVLIEKDWISFGHKFSERCGHLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFNEAFLLQIHEHIHSCQFGNFIGNCQKEREELKLKEKTYSLWPFLLDDQKKYLNPLYSSQSQKSAVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESQIKQRKTKQTDGILSKELLNSVRPESPALKATLSLKEQALLPVNNVLRTIEGSSPADNRYSEYADEFSKAEPAVVSLEYGVARMTC", "length": 621, "header": "tr|E1BJH8-1|E1BJH8_BOVIN Isoform 1 of Myotubularin related protein 6 OS=Bos taurus OX=9913 GN=MTMR6 PE=3 SV=3 CANONICAL=E1BJH8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LYK5-1", "url": "https://www.uniprot.org/uniprotkb/E1BJH8/entry#A0A3Q1LYK5-1", "sequence": { "sequence": "MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDAHQKETWILHHHIASVEKLALTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDAERLRGWELIDLAEEYKRMGVPNSNWQLSDANREYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQSKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPANRYMYVMDTRPRLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAVMDAAIFLAKAIAAESASVLVHCSDGWDRTSQVCSLGSLLLDPYYRTIRGFMVLIEKDWISFGHKFSERCGHLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFNEAFLLQIHEHIHSCQFGNFIGNCQKEREELKLKEKTYSLWPFLLDDQKKYLNPLYSSQSQKSAVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESITAVSGDRPGGQAESTLTTLGQSDATRPTSC", "length": 566, "header": "tr|A0A3Q1LYK5-1|E1BJH8_BOVIN Computationally mapped isoform of Myotubularin related protein 6 OS=Bos taurus OX=9913 GN=MTMR6 PE=3 SV=2 CANONICAL=E1BJH8-1" }, "locus": { "chromosome": "12", "start_pos": 33968465, "end_pos": 33932198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069408.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069408.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062673.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062673.2" } ] } }, { "isoform_ac": "A0AAA9S5S3-1", "url": "https://www.uniprot.org/uniprotkb/E1BJH8/entry#A0AAA9S5S3-1", "sequence": { "sequence": "MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDAHQKETWILHHHIASVEKLALTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDAERLRGWELIDLAEEYKRMGVPNSNWQLSDANREYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQSKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPANRYMYVMDTRPRHRVQSWWATQKDIGRIIVRISSKIWNDEKIRESDEKKRLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAVMDAAIFLAKAIAAESASVLVHCSDGWDRTSQVCSLGSLLLDPYYRTIRGFMVLIEKDWISFGHKFSERCGHLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFNEAFLLQIHEHIHSCQFGNFIGNCQKEREELKLKEKTYSLWPFLLDDQKKYLNPLYSSQSQKSAVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESQIKQRKTKQTDGILSKELLNSVRPESPALKATLSLKEQALLPVNNVLRTIEGSSPADNRYSEYADEFSKAEPAVVSLEYGVARMTC", "length": 659, "header": "tr|A0AAA9S5S3-1|E1BJH8_BOVIN Computationally mapped isoform of Myotubularin related protein 6 OS=Bos taurus OX=9913 GN=MTMR6 PE=3 SV=1 CANONICAL=E1BJH8-1" }, "locus": { "chromosome": "12", "start_pos": 33950555, "end_pos": 33932198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100121.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100121.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077511.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077511.1" } ] } }, { "isoform_ac": "E1BJH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BJH8/entry#E1BJH8-1", "sequence": { "sequence": "MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDAHQKETWILHHHIASVEKLALTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDAERLRGWELIDLAEEYKRMGVPNSNWQLSDANREYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQSKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPANRYMYVMDTRPRLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAVMDAAIFLAKAIAAESASVLVHCSDGWDRTSQVCSLGSLLLDPYYRTIRGFMVLIEKDWISFGHKFSERCGHLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFNEAFLLQIHEHIHSCQFGNFIGNCQKEREELKLKEKTYSLWPFLLDDQKKYLNPLYSSQSQKSAVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESQIKQRKTKQTDGILSKELLNSVRPESPALKATLSLKEQALLPVNNVLRTIEGSSPADNRYSEYADEFSKAEPAVVSLEYGVARMTC", "length": 621, "header": "tr|E1BJH8-1|E1BJH8_BOVIN Isoform 1 of Myotubularin related protein 6 OS=Bos taurus OX=9913 GN=MTMR6 PE=3 SV=3 CANONICAL=E1BJH8-1" }, "locus": { "chromosome": "12", "start_pos": 33950555, "end_pos": 33932198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004052.8", "url": "https://www.ensembl.org/id/ENSBTAT00000004052.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004052.6", "url": "https://www.ensembl.org/id/ENSBTAP00000004052.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JXT6-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6", "gene_name": "Mtmr6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHIRTTKVEQVKLLDRFSTNNKSLTGTLYLTATHLLFIDAHQKETWILHHHIASVEKLALTTSGCPLVIQCKNFRIVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDTERLNGWQLIDLAAEYERMGVPNANWQLSDANREYKVCETYPRELYVPRTASRPVIVGSSNFRSKGRLPVLSYCQQGTEAAICRCSQPLSGFSARCLEDEHLLQAISKANPGNRYMYVVDTRPKLRMQSWWDTQKDIGRIIVRISSKIWNDEKIRESDEKKRLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGSKGLSVNDFYSGLESSGWLRHIKAVLDAAIFLAKAIVVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTMKGFMVLIEKDWISFGHKFSERCGHLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFNEAFLLQIHEHIHSCQFGNFLGNCQKEREELRLKEKTYSLWPFLLADKKKYLNPLYSSKSQRLTVLEPNTASFNFKFWRNMYHQFDRTLHPRQSVLNIIMNMNEQNKQLEEDVKDLEAKIKQCKSGILTKDLLHAVHPESPSLKTSLCLKEQSLLPVKDTLRAVEGSSPADNRYCDYTEEFSKSEPAVVSLEYGVARMTC", "length": 655 }, "evidence": [ { "id": "E1BJH8", "url": "https://omabrowser.org/oma/group/E1BJH8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287BBV4-1", "protein_name": "Myotubularin related protein 6", "gene_name": "MTMR6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEHIRTTKVEQVKLLDRFSTSSKSLTGTLYLTATHLLFIDSHQKETWILHHHIASVDKLALTTAGCPLVIQCKNFRIVHFVVPRERDCHDVYNSLLQLSKQAKYEDLYAFSYNPQQNESERQRGWQLLDLAEEYKRMGLPNSNWQLSDANRDYKICETYPRDLYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQAKEAAICRCSQPLSGFSARCLEDEHLLQAISKATPANRFMYVMDTRPRLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAVLDAAIFLARAIVVESASVLVHCSDGWDRTAQVCSLGSLLLDPYYRTLRGFLVLIEKDWISFGHKFSERCGHLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFNEACLLQIHEHVHSCQFGNFLGNCQKEQEELKLKEKTYSLWPLLLDDQRPYLNPLYSPRAQVAAALEPNTVSFNFKFWRNMYHQFDRTLHPRQSVLNIIMNMSEQTKQLEKDVKDLESQLNKQRKNKHADGVLTKELLNSVRPESPTLKTSLCFKEQTLLPGNAALRTIEGSNPADNRYSEYAEEFSKSEPAVVSLEYGVARMTC", "length": 622 }, "evidence": [ { "id": "E1BJH8", "url": "https://omabrowser.org/oma/group/E1BJH8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8MLR7-1", "protein_name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "gene_name": "Mtmr6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDITRFMNKFNEIERQLSPTSALRLSFDNISPETEEPPDGNKRLWGVPVPPFVSEKVVSWIEEEFNEAPVFYNGNSVLKKVENVRMIDRYNTKNPTVGTLYLTATHLIFVEPDSNKETWILHMHVASIEKLPLSTTGSPLLIRCKTFLSVTFVIPKDSECHDVYTSLLKLFQPVSINKLYCFNYQPNKDDFPKNAGWDYFKLEAEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHNNKASICRCSQPLSGFSARCLEDEQMLEAIRKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEQKSPTMSAFINALESSGWLKHIRSILDTSSFIANAVDKGVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHIQTDAREVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVDEAIKANLAPQCIKFWRGMYSRFESGIHPREPLGDVLLDSKEHCNSLEDHVQHLTKRIASFKNYISKSAKKLQDATSAPGKVNKELSSNEINDNKYNYDKKLSELSAADDDHPLKASNMSFASLSLSAEQSSPPQALPEEINSVAVDWKPMRNVTTCSCSTPFDQFSKKTHCWRCGDIFCERCIDKNVALPGHDSGKPVPVCRGCFRQMQKQSP", "length": 761 }, "evidence": [ { "id": "E1BJH8", "url": "https://omabrowser.org/oma/group/E1BJH8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8VE11-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6", "gene_name": "Mtmr6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEHIRTTKVEQVKLLDRFSTNNKSLTGTLYLTATHLLFIDAQQKETWILHHHIASVEKLALTTSGCPLVIQCKNFRIVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDTERRNGWQLIDLAAEYERMGVPNANWQLSDANREYKVCETYPRELYVPRTASRPVIVGSSNFRSKGRLPVLSYCRQGTEAAICRCSQPLSGFSARCLEDEHLLQAISKANPGNRYMYVVDTRPKLNAIANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGSKGLSVNDFYSGLESSGWLRHIKAVLDAAIFLAKAIVVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTMKGFMVLIEKDWISFGHKFSERCGHLDGDPREVSPVFTQFLECVWHLTQQFPQAFEFNEAFLLQIHEHIHSCQFGNFLGNCQKEREELRLKEKTYSLWPFLLDDKKKYLNPLYSSKSQRLTVLEPNTASFNFKFWRNMYHQFDRTLHPRQSVLSIIMNMNEQSKQLEEDIKDLEAKIKQCKNGILTKELLHAVHPESPALKTSLCLKEPSLLPVKDTLRAIEGSSPADNRYCDYAEEFSKSEPTVVSLEYGVARMTC", "length": 617 }, "evidence": [ { "id": "E1BJH8", "url": "https://omabrowser.org/oma/group/E1BJH8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y217-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6", "gene_name": "MTMR6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDSHQKETWILHHHIASVEKLALTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDSERLQGWQLIDLAEEYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQTDGILTKELLHSVHPESPNLKTSLCFKEQTLLPVNDALRTIEGSSPADNRYSEYAEEFSKSEPAVVSLEYGVARMTC", "length": 621 }, "evidence": [ { "id": "E1BJH8", "url": "https://omabrowser.org/oma/group/E1BJH8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphatidylinositol-3,5-bisphosphate phosphatase activity", "id": "GO:0106018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106018", "evidence": [ { "database": "UniProtKB", "id": "E1BJH8", "url": "https://www.uniprot.org/uniprotkb/E1BJH8" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate phosphatase activity", "id": "GO:0004438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004438", "evidence": [ { "database": "UniProtKB", "id": "E1BJH8", "url": "https://www.uniprot.org/uniprotkb/E1BJH8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1BJH8", "url": "https://www.uniprot.org/uniprotkb/E1BJH8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "E1BJH8", "url": "https://www.uniprot.org/uniprotkb/E1BJH8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BJH8", "url": "https://www.uniprot.org/uniprotkb/E1BJH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "E1BJH8", "url": "https://www.uniprot.org/uniprotkb/E1BJH8" } ], "pmid": "" }, { "name": "phosphatidylinositol metabolic process", "id": "GO:0046488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046488", "evidence": [ { "database": "UniProtKB", "id": "E1BJH8", "url": "https://www.uniprot.org/uniprotkb/E1BJH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH8" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 499, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 288, "end_pos": 290 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK15-1", "uniprot_ac": "E1BK15", "uniprot_id": "E1BK15_BOVIN", "mass": { "chemical_mass": 97235.0, "monoisotopic_mass": 97235.0 }, "refseq": { "ac": "NP_001192799", "name": "H(+)/Cl(-) exchange transporter 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192799" }, "gene_names": [ { "name": "CLCN6", "type": "recommended", "evidence": [ { "id": "E1BK15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK15" } ] }, { "name": "CLCN6", "type": "synonym", "evidence": [ { "id": "NP_001192799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192799" } ] } ], "protein_names": [ { "name": "Chloride channel protein", "type": "recommended", "evidence": [ { "id": "E1BK15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK15/entry#names_and_taxonomy" } ] }, { "name": "H(+)/Cl(-) exchange transporter 6", "type": "synonym", "evidence": [ { "id": "NP_001192799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192799" } ] }, { "name": "chloride channel 6", "type": "synonym", "evidence": [ { "id": "NP_001192799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192799" } ] } ], "function": [ { "annotation": "Voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the late endosome lumen. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters.", "evidence": [ { "database": "UniProtKB", "id": "E1BK15", "url": "https://www.uniprot.org/uniprotkb/E1BK15#function" }, { "database": "UniProtKB", "id": "ARBA00056509", "url": "https://www.uniprot.org/uniprotkb/ARBA00056509#function" }, { "database": "UniProtKB", "id": "A0AAA9SSH5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSH5#function" }, { "database": "UniProtKB", "id": "A0AAA9S6C2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6C2#function" }, { "database": "UniProtKB", "id": "A0AAA9U0K4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0K4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK15", "url": "https://www.uniprot.org/uniprotkb/E1BK15" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CLCN6", "url": "https://www.uniprot.org/uniprotkb/E1BK15", "locus": { "chromosome": "16", "start_pos": 41841830, "end_pos": 41873724, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020700", "url": "https://www.ensembl.org/id/ENSBTAG00000020700" } ] } } ], "crossref": [ { "id": "E1BK15", "url": "https://alphafold.ebi.ac.uk/entry/E1BK15", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020700", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020700", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03685", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03685", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04591", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04591", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "520210", "url": "https://www.ncbi.nlm.nih.gov/gene/520210", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:520210", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520210", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FARIDHG", "url": "https://omabrowser.org/oma/group/FARIDHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BK15", "url": "https://www.orthodb.org/?gene=E1BK15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11689", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11689", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11689:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11689:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192799", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192799", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29567", "url": "https://www.rhea-db.org/rhea/29567", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S6C2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6C2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6C2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSH5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSH5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0K4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0K4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK15", "url": "https://www.uniprot.org/uniprotkb/E1BK15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK15-1", "url": "https://www.uniprot.org/uniprotkb/E1BK15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGCRGSLCCCCRWCCCCGDRETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDPYLEVLETMDNKKGRKYEAVKWMMVFAIGVCTGLVGLFVDFFARLFTQLKFGVVQASVEECSQKGCLALSLLELLGFNLTFVFFASLLVLIEPVAAGSGIPEIKCYLNGVKVPGIVRLRTLLCKVFGVLFSVAGGLFVGKEGPMIHSGAVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWRVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFIAMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVTLVTTVVVFVASMVLGECRQVTSAAQVGNDSIPLQVTSEDVNSSIKTFFCPNETYNDMATLFFNPQESAILQLFHQDSTFSPVTLALFFVLYFSLACWTYGISVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMITLMVAKWTGDFFNKGIYDIHVGLRGVPLLEWETEVEMDKLRASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEREFMKGNQLISNNIKFKKSSILTRAGEQRRRSQSMKSYPSSELRNMCDEHVTSEEPGEKEDLLQQMLERRYTPYPNLYPDQSPSEDWTMEERFRPLTFHGLILRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAEDYPRYPDIHDLDLTLLNPRMIVDVTPYMNPAPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGVITRHNLTHEFLQARLRQHYQTL", "length": 870, "header": "tr|E1BK15-1|E1BK15_BOVIN Isoform 1 of Chloride channel protein OS=Bos taurus OX=9913 GN=CLCN6 PE=3 SV=1 CANONICAL=E1BK15-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S6C2-1", "url": "https://www.uniprot.org/uniprotkb/E1BK15/entry#A0AAA9S6C2-1", "sequence": { "sequence": "MAGCRGSLCCCCRWCCCCGDRETRTPEELTILGETQEEEDEILPRKDYEKGRKYEAVKWMMVFAIGVCTGLVGLFVDFFARLFTQLKFGVVQASVEECSQKGCLALSLLELLGFNLTFVFFASLLVLIEPVAAGSGIPEIKCYLNGVKVPGIVRLRTLLCKVFGVLFSVAGGLFVGKEGPMIHSGAVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWRVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFIAMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVTLVTTVVVFVASMVLGECRQVTSAAQVGNDSIPLQVTSEDVNSSIKTFFCPNETYNDMATLFFNPQESAILQLFHQDSTFSPVTLALFFVLYFSLACWTYGISVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMITLMVAKWTGDFFNKGIYDIHVGLRGVPLLEWETEVEMDKLRASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEREFMKGNQLISNNIKFKKSSILTRAGEQRRRSQSMKSYPSSELRNMCDEHVTSEEPGEKEDLLQQMLERRYTPYPNLYPDQSPSEDWTMEERFRPLTFHGLILRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAEDYPRYPDIHDLDLTLLNPRMIVDVTPYMNPAPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGVITRHNLTHEFLQARLRQHYQTL", "length": 848, "header": "tr|A0AAA9S6C2-1|E1BK15_BOVIN Computationally mapped isoform of Chloride channel protein OS=Bos taurus OX=9913 GN=CLCN6 PE=3 SV=1 CANONICAL=E1BK15-1" }, "locus": { "chromosome": "16", "start_pos": 41872613, "end_pos": 41841887, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095787.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095787.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078843.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078843.1" } ] } }, { "isoform_ac": "A0AAA9SSH5-1", "url": "https://www.uniprot.org/uniprotkb/E1BK15/entry#A0AAA9SSH5-1", "sequence": { "sequence": "MTILGETQEEEDEILPRKDYESLDYDRCINDPYLEVLETMDNKKGRKYEAVKWMMVFAIGVCTGLVGLFVDFFARLFTQLKFGVVQASVEECSQKGCLALSLLELLGFNLTFVFFASLLVLIEPVAAGSGIPEIKCYLNGVKVPGIVRLRTLLCKVFGVLFSVAGGLFVGKEGPMIHSGAVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWRVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFIAMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVTLVTTVVVFVASMVLGECRQVTSAAQVGNDSIPLQVTSEDVNSSIKTFFCPNETYNDMATLFFNPQESAILQLFHQDSTFSPVTLALFFVLYFSLACWTYGISVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMITLMVAKWTGDFFNKGIYDIHVGLRGVPLLEWETEVEMDKLRASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEREFMKGNQLISNNIKFKKSSILTRAGEQRRRSQSMKSYPSSELRNMCDEHVTSEEPGEKEDLLQQMLERRYTPYPNLYPDQSPSEDWTMEERFRPLTFHGLILRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAEDYPRYPDIHDLDLTLLNPRMIVDVTPYMNPAPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGVITRHNLTHEFLQARLRQHYQTL", "length": 842, "header": "tr|A0AAA9SSH5-1|E1BK15_BOVIN Computationally mapped isoform of Chloride channel protein OS=Bos taurus OX=9913 GN=CLCN6 PE=3 SV=1 CANONICAL=E1BK15-1" }, "locus": { "chromosome": "16", "start_pos": 41871954, "end_pos": 41841887, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111623.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111623.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087070.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087070.1" } ] } }, { "isoform_ac": "A0AAA9U0K4-1", "url": "https://www.uniprot.org/uniprotkb/E1BK15/entry#A0AAA9U0K4-1", "sequence": { "sequence": "MAGCRGSLCCCCRWCCCCGDRETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDPYLEVLETMDNKKGRKYEAVKWMMVFAIGVCTGLPVAAGSGIPEIKCYLNGVKVPGIVRLRTLLCKVFGVLFSVAGGLFVGKEGPMIHSGAVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWRVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFIAMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVTLVTTVVVFVASMVLGECRQVTSAAQVGNDSIPLQVTSEDVNSSIKTFFCPNETYNDMATLFFNPQESAILQLFHQDSTFSPVTLALFFVLYFSLACWTYGISVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMITLMVAKWTGDFFNKGIYDIHVGLRGVPLLEWETEVEMDKLRASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEREFMKGNQLISNNIKFKKSSILTRAGEQRRRSQSMKSYPSSELRNMCDEHVTSEEPGEKEDLLQQMLERRYTPYPNLYPDQSPSEDWTMEERFRPLTFHGLILRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAEDYPRYPDIHDLDLTLLNPRMIVDVTPYMNPAPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGVITRHNLTHEFLQARLRQHYQTL", "length": 812, "header": "tr|A0AAA9U0K4-1|E1BK15_BOVIN Computationally mapped isoform of Chloride channel protein OS=Bos taurus OX=9913 GN=CLCN6 PE=3 SV=1 CANONICAL=E1BK15-1" }, "locus": { "chromosome": "16", "start_pos": 41872613, "end_pos": 41841887, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089967.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089967.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103478.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103478.1" } ] } }, { "isoform_ac": "E1BK15-1", "url": "https://www.uniprot.org/uniprotkb/E1BK15/entry#E1BK15-1", "sequence": { "sequence": "MAGCRGSLCCCCRWCCCCGDRETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDPYLEVLETMDNKKGRKYEAVKWMMVFAIGVCTGLVGLFVDFFARLFTQLKFGVVQASVEECSQKGCLALSLLELLGFNLTFVFFASLLVLIEPVAAGSGIPEIKCYLNGVKVPGIVRLRTLLCKVFGVLFSVAGGLFVGKEGPMIHSGAVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWRVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFIAMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVTLVTTVVVFVASMVLGECRQVTSAAQVGNDSIPLQVTSEDVNSSIKTFFCPNETYNDMATLFFNPQESAILQLFHQDSTFSPVTLALFFVLYFSLACWTYGISVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMITLMVAKWTGDFFNKGIYDIHVGLRGVPLLEWETEVEMDKLRASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEREFMKGNQLISNNIKFKKSSILTRAGEQRRRSQSMKSYPSSELRNMCDEHVTSEEPGEKEDLLQQMLERRYTPYPNLYPDQSPSEDWTMEERFRPLTFHGLILRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAEDYPRYPDIHDLDLTLLNPRMIVDVTPYMNPAPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGVITRHNLTHEFLQARLRQHYQTL", "length": 870, "header": "tr|E1BK15-1|E1BK15_BOVIN Isoform 1 of Chloride channel protein OS=Bos taurus OX=9913 GN=CLCN6 PE=3 SV=1 CANONICAL=E1BK15-1" }, "locus": { "chromosome": "16", "start_pos": 41872613, "end_pos": 41841887, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027587.5", "url": "https://www.ensembl.org/id/ENSBTAT00000027587.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027587.3", "url": "https://www.ensembl.org/id/ENSBTAP00000027587.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:520210", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520210", "resource": "KEGG Pathway" }, { "id": "R-BTA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A3H5-1", "protein_name": "Chloride channel protein", "gene_name": "Clcn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGCRGSVCCCCRWCCCCGERESRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDPYLEVLETMDNKKGRRHEAVKWMVVFAIGVCTGLVGLFVDFSVRLFTQLKFGVVQTCILSTAPLFQTLGFSRLFLPVAAGSGIPEIKCYLNGVKVPGIVRLRTLLCKVFGVLFSVAGGLFVGKEGPMIHSGAVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGSWGAFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFVVMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVSLVTTVVVFVASMVLGECRQMSSTSQTGNGSFQLQVTSEDVNSTIKTFFCPNDTYNDMATLFFNSQESAILQLFHQDGTFSPVTLALFFALYFLMACWTFGTSVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHLYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMVTLMVAKWTGDFFNKGIYDIHIGLRGVPLLEWETEVEMDRLRASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEKEFMKGNQLISNNIKFKKSSILTRAGEQRKRGQSMKSYPSSELRNVCDEHVASEEPAEKEDLLQQMLERRYTPYPNLYPDQSPSEDWTMEERFRPLTFHGLVLRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAEDYPRFPDIHDLDLTLLNPRMIVDVTPYMNPSPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGIITRHNLTTEFLQARLRQHYQTL", "length": 853 }, "evidence": [ { "id": "E1BK15", "url": "https://omabrowser.org/oma/group/E1BK15/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F798-1", "protein_name": "Chloride channel protein", "gene_name": "clcn6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MACCGGCLCCQCCCNEGETRTPEELTILGETREDDDEILPRKDYESLDYDRCINEPFLEVLEGLDNKKARKYEAIKWILVFAIGVSTGLTGLFVDFFVRLFTQLKFNVVGQSVEECSENGCLALSLLELLALNMMFVFISSVLVLIEPVAAGSGIPEIKSYLNGVKVPGIVRLRTFICKVTGVLFAVAGGLFVGKEGPMIHSGAIVGAGLPQFQSITFKKIRFHFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQALTWKVLFCSMSATFTLNFFRSGINFSKWGSFQLPGLLNFGEFKCPDGDKACHLWTAVDLAFFVLMGVAGGLLGALFNCINKRLAKYRMRNVHPKARFIRVLESLLVCMVTTLVIFMSSMTLGECRDLVSNVNNNTSTQGSVNEEVNSTIRRFFCYNNTYNDMATLFFNPQEVAIHQLFHQNATFSPVTLSLFFVLYFFLSCWTYGVSVPSGLFVPSLLCGASLGRLLANVLKINFHMQIYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMITLMVAKWTGDFFNRGIYDIHIHLKGVPLLEWETEVEMDKLTASDIMEPNLTYVYPHTRIQSLVSILRTTVYHAFPVVTENRDNEKEFMKGNILISNNIKFKKTSVLTRAGEQRRRCQSMKSYPSSELRNVCDEHVVVEPTEEGQDILQQMLERRHAPYPNLYPDQSPSEEWTMEERFRPLTFHGLILRSQLVNLLIRGVCYAENQSSASQPRLSHSEMTEDYPRFPDIHDLDLALLNPRMIVDVTPYMNPCPYTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGIITRHNLTHEFLVAKLRQHYITI", "length": 863 }, "evidence": [ { "id": "E1BK15", "url": "https://omabrowser.org/oma/group/E1BK15/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35454-1", "protein_name": "H(+)/Cl(-) exchange transporter 6", "gene_name": "Clcn6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGCRGSVCCCCRWCCCCGERESRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDPYLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFSVRLFTQLKFGVVQTSVEECSQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEIKCYLNGVKVPGIVRLRTLLCKVFGVLFSVSGGLFVGKEGPMIHSGAVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFVVMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVSLVTTVVVFVASMVLGECRQMSSTSQTGNGSFQLQVTSEDVNSTIKAFFCPNDTYNDMATLFFNSQESAILQLFHQDGTFSPVTLALFFILYFLLACWTFGTSVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHLYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMVTLMVAKWTGDLFNKGIYDVHIGLRGVPLLEWETDVEMDKLRASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEKEFMKGNQLISNNIKFKKSSILTRAGEQRKRGQSMKSYPSSELRNVCDEHVASEEPAEKEDLLQQMLERRYTPYPNLYPDQSPSEDWTMEERFRPLTFHGLVLRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAEDYPRYPDIHDLDLTLLNPRMIVDVTPYMNPSPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGIITRHNLTNEFLQARLRQHYQTL", "length": 870 }, "evidence": [ { "id": "E1BK15", "url": "https://omabrowser.org/oma/group/E1BK15/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P51797-1", "protein_name": "H(+)/Cl(-) exchange transporter 6", "gene_name": "CLCN6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDPYLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEECSQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGGLFVEKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFVVMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVSLVTTVVVFVASMVLGECRQMSSSSQIGNDSFQLQVTEDVNSSIKTFFCPNDTYNDMATLFFNPQESAILQLFHQDGTFSPVTLALFFVLYFLLACWTYGISVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMVTLMVAKWTGDFFNKGIYDIHVGLRGVPLLEWETEVEMDKLRASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEKEFMKGNQLISNNIKFKKSSILTRAGEQRKRSQSMKSYPSSELRNMCDEHIASEEPAEKEDLLQQMLERRYTPYPNLYPDQSPSEDWTMEERFRPLTFHGLILRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAEDYPRYPDIHDLDLTLLNPRMIVDVTPYMNPSPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGIITRHNLTYEFLQARLRQHYQTI", "length": 869 }, "evidence": [ { "id": "E1BK15", "url": "https://omabrowser.org/oma/group/E1BK15/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P92941-1", "protein_name": "Chloride channel protein CLC-a", "gene_name": "CLC-A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDEDGNLQISNSNYNGEEEGEDPENNTLNQPLLKRHRTLSSTPLALVGAKVSHIESLDYEINENDLFKHDWRSRSKAQVFQYIFLKWTLACLVGLFTGLIATLINLAVENIAGYKLLAVGYYIAQDRFWTGLMVFTGANLGLTLVATVLVVYFAPTAAGPGIPEIKAYLNGIDTPNMFGFTTMMVKIVGSIGAVAAGLDLGKEGPLVHIGSCIASLLGQGGPDNHRIKWRWLRYFNNDRDRRDLITCGSASGVCAAFRSPVGGVLFALEEVATWWRSALLWRTFFSTAVVVVVLRAFIEICNSGKCGLFGSGGLIMFDVSHVEVRYHAADIIPVTLIGVFGGILGSLYNHLLHKVLRLYNLINQKGKIHKVLLSLGVSLFTSVCLFGLPFLAECKPCDPSIDEICPTNGRSGNFKQFNCPNGYYNDLSTLLLTTNDDAVRNIFSSNTPNEFGMVSLWIFFGLYCILGLITFGIATPSGLFLPIILMGSAYGRMLGTAMGSYTNIDQGLYAVLGAASLMAGSMRMTVSLCVIFLELTNNLLLLPITMFVLLIAKTVGDSFNLSIYEIILHLKGLPFLEANPEPWMRNLTVGELNDAKPPVVTLNGVEKVANIVDVLRNTTHNAFPVLDGADQNTGTELHGLILRAHLVKVLKKRWFLNEKRRTEEWEVREKFTPVELAEREDNFDDVAITSSEMQLYVDLHPLTNTTPYTVVQSMSVAKALVLFRSVGLRHLLVVPKIQASGMSPVIGILTRQDLRAYNILQAFPHLDKHKSGKAR", "length": 775 }, "evidence": [ { "id": "E1BK15", "url": "https://omabrowser.org/oma/group/E1BK15/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q86AZ6-1", "protein_name": "Chloride channel protein B", "gene_name": "clcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNNYKAGTAINGNDYLLLNIDGNKDCDTDNGFFSGKNFFGGNQTSITHRRHHKMTTKTDRELMSHFESLDFNAIDNIIHRKYTFEKKKYQKILKTLGKWVICTLIGVVVGLVCYCLKESVDQLQSLKLTQVKKFYSTESTIFIPFLVYLGFNLCYGLISGLLVCIFGPMSSSSGLPEVKGYLNGIRISKAFNLKTVLGKLVSLIFSFSSGLVLGPEGPMFHIGAGIGSSMSQFKSKTLKFHLKSFWIFQNDSDKRDFISCGAAAGIAAAFGAPIGGVLFCLEEGSSFWSRQLTWRTFFSCLIATMTANLFLQGFTQQIHDYGVLTFGVSKSYLYTYTELIPFMIMGIIGGLLGAIFVHVNVRVNHWRKKLFANKSKLYKMIEVCVIVILSSVVCFFPALLADCRPISGISGLTPGTCDPGDDSTLILNQFNCAEGYYNPMATLTLTTLENSLQIVFSRSTNIFTAQTLLTFSIFYYVLTIITSGLYVASGIFIPMMLIGSSWGRLIGIFLSKYFTSIDPSIYALIGAASMMAGSLRMTISLVVIIVELTETTQYLLPVILSVMVGKWCGDIFNESIYEHLIELKHIPYLNSQPPNHLRKKTVAEAMSTDVKTLPEIVKVKTALTILETCPHNGFPVVMLPQLHSNSNLNDSNQLSLSLNLNNNNNNNNNNNNNNNNNNNNNNNNNNNNILCGLILRSQLSVLLRRKIFNSPEDLKNIDFISDKGYNLPIDHTEFSQELASKIPPIHELSKLITKEDLDMYIDLRPYMNFAVVSIKNYSSLSEAYQIFRQVGLRHMVVINVFNNVVGMLTRKDLC", "length": 815 }, "evidence": [ { "id": "E1BK15", "url": "https://omabrowser.org/oma/group/E1BK15/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BK15", "url": "https://www.uniprot.org/uniprotkb/E1BK15" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "E1BK15", "url": "https://www.uniprot.org/uniprotkb/E1BK15" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "E1BK15", "url": "https://www.uniprot.org/uniprotkb/E1BK15" } ], "pmid": "" }, { "name": "voltage-gated chloride channel activity", "id": "GO:0005247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005247", "evidence": [ { "database": "UniProtKB", "id": "E1BK15", "url": "https://www.uniprot.org/uniprotkb/E1BK15" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "E1BK15", "url": "https://www.uniprot.org/uniprotkb/E1BK15" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chloride transport", "id": "GO:0006821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006821", "evidence": [ { "database": "UniProtKB", "id": "E1BK15", "url": "https://www.uniprot.org/uniprotkb/E1BK15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 853, "end_pos": 855, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29567", "name": "", "equation": "2 chloride(in) + H(+)(out) = 2 chloride(out) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29567", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29567" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BK15-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 870, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BK15-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BK15" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BK15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK15" }, { "id": "PS51371", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51371" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBS", "eco_id": "ECO_0000259", "start_pos": 808, "end_pos": 869, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 853, "end_pos": 855 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHZ6-1", "uniprot_ac": "E1BHZ6", "uniprot_id": "E1BHZ6_BOVIN", "mass": { "chemical_mass": 68820.0, "monoisotopic_mass": 68820.0 }, "refseq": {}, "gene_names": [ { "name": "GLS2", "type": "recommended", "evidence": [ { "id": "E1BHZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6" } ] } ], "protein_names": [ { "name": "glutaminase", "type": "recommended", "evidence": [ { "id": "E1BHZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6/entry#names_and_taxonomy" } ] }, { "name": "3.5.1.2", "type": "synonym", "evidence": [ { "id": "E1BHZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHZ6", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GLS2", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6", "locus": { "chromosome": "5", "start_pos": 56923311, "end_pos": 56910595, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009284", "url": "https://www.ensembl.org/id/ENSBTAG00000009284" } ] } } ], "crossref": [ { "id": "E1BHZ6", "url": "https://alphafold.ebi.ac.uk/entry/E1BHZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009284", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009284", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BHZ6", "url": "https://www.orthodb.org/?gene=E1BHZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12544", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12544", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12544:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12544:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04960", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04960", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-210500", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-210500", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8964539", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8964539", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "15889", "url": "https://www.rhea-db.org/rhea/15889", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S8X6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8X6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWE2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TK95", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TK95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TK95-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TK95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0H4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0H4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHZ6", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHZ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSFKALQNSLSRAGSHCRRGGWGHLSQNPLLTWGVRHHLSEAAAQGKETPHSHQTQHQDQRSREQFSGSCPSPLSLPPNSDSSESGMLSRLGDLLFYTIGEGQERIPIHKFTTALKATGLQTSDPRLRDCMSQMRRMVRQSNSGGLLDRDLFRKCVSSNIVLLTQAFRKKFVIPDFEEFTSHVDRIFEDAKELTGGKVAAYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHKFVGKEPSGLRYNTLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNIMGMMCLSPPLDKLGNSYRGVNFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAASSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTPSETWAEAAAEALSKENLESMV", "length": 622, "header": "tr|E1BHZ6-1|E1BHZ6_BOVIN Isoform 1 of glutaminase OS=Bos taurus OX=9913 GN=GLS2 PE=3 SV=5 CANONICAL=E1BHZ6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S8X6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6/entry#A0AAA9S8X6-1", "sequence": { "sequence": "MRSFKALQNSLSRAGSHCRRGGWGHLSQNPLLTWGVRHHLSEAAAQGKETPHSHQTQHQDHDSSESGMLSRLGDLLFYTIGEGQERIPIHKFTTALKATGLQTSDPRLRDCMSQMRRMVRQSNSGGLLDRDLFRKCVSSNIVLLTQAFRKKFVIPDFEEFTSHVDRIFEDAKELTGGKVAAYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHKFVGKEPSGLRYNTLSLNEEGIPHNPMVNAGAIVVSSLIKVLQYLNKMAGNEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNIMGMMCLSPPLDKLGNSYRGVNFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAASSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTPSETWAEAAAEALSKENLESMV", "length": 591, "header": "tr|A0AAA9S8X6-1|E1BHZ6_BOVIN Computationally mapped isoform of glutaminase OS=Bos taurus OX=9913 GN=GLS2 PE=3 SV=1 CANONICAL=E1BHZ6-1" }, "locus": { "chromosome": "5", "start_pos": 56922800, "end_pos": 56910794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133567.2", "url": "https://www.ensembl.org/id/ENSBTAT00000133567.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080373.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080373.1" } ] } }, { "isoform_ac": "A0AAA9SWE2-1", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6/entry#A0AAA9SWE2-1", "sequence": { "sequence": "MRSFKALQNSLSRAGSHCRRGGWGHLSQNPLLTWGVRHHLSEAAAQGKETPHSHQTQHQDHDSSESGMLSRLGDLLFYTIGEGQERIPIHKFTTALKATGLQTSDPRLRDCMSQMRRMVRQSNSGGLLDRDLFRKCVSSNIVLLTQAFRKKFVIPDFEEFTSHVDRIFEDAKELTGGKVAAYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHKFVGKEPSGLRYNTLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNIMGMMCLSPPLDKLGNSYRGVNFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAASSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTPSETWAEAAAEALSKENLESMV", "length": 560, "header": "tr|A0AAA9SWE2-1|E1BHZ6_BOVIN Computationally mapped isoform of glutaminase OS=Bos taurus OX=9913 GN=GLS2 PE=3 SV=1 CANONICAL=E1BHZ6-1" }, "locus": { "chromosome": "5", "start_pos": 56922800, "end_pos": 56910794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106468.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106468.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090792.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090792.1" } ] } }, { "isoform_ac": "A0AAA9TK95-1", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6/entry#A0AAA9TK95-1", "sequence": { "sequence": "MRSFKALQNSLSRAGSHCRRGGWGHLSQNPLLTWGVRHHLSEAAAQGKETPHSHQTQHQDHDSSESGMLSRLGDLLFYTIGEGQERIPIHKFTTALKATGLQTSDPRLRDCMSQMRRMVRQSNSGGLLDRDLFRKCVSSNIVLLTQAFRKKFVIPDFEEFTSHVDRIFEDAKELTGGKVAAYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHKFVGKEPSGLRYNTLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNIMGMMCLSPPLDKLGNSYRGVNFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAASSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFVKDR", "length": 551, "header": "tr|A0AAA9TK95-1|E1BHZ6_BOVIN Computationally mapped isoform of glutaminase OS=Bos taurus OX=9913 GN=GLS2 PE=3 SV=2 CANONICAL=E1BHZ6-1" }, "locus": { "chromosome": "5", "start_pos": 56922496, "end_pos": 56910794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129443.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129443.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096681.2", "url": "https://www.ensembl.org/id/ENSBTAP00000096681.2" } ] } }, { "isoform_ac": "A0AAA9U0H4-1", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6/entry#A0AAA9U0H4-1", "sequence": { "sequence": "MRSFKALQNSLSRAGSHCRRGGWGHLSQNPLLTWGVRHHLSEAAAQGKETPHSHQTQHQDQRSREQFSGSCPSPLSLPPNSDSSESGMLSRLGDLLFYTIGEGQERIPIHKFTTALKATGLQTSDPRLRDCMSQMRRMVRQSNSGGLLDRDLFRKCVSSNIVLLTQAFRKKFVIPDFEEFTSHVDRIFEDAKELTGGKVAAYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHKFVGKEPSGLRYNTLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQVGLPAKSAVSGAILLVVPNIMGMMCLSPPLDKLGNSYRGVNFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAASSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTPSETWAEAAAEALSKENLESMV", "length": 563, "header": "tr|A0AAA9U0H4-1|E1BHZ6_BOVIN Computationally mapped isoform of glutaminase OS=Bos taurus OX=9913 GN=GLS2 PE=3 SV=2 CANONICAL=E1BHZ6-1" }, "locus": { "chromosome": "5", "start_pos": 56922800, "end_pos": 56910794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102566.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102566.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103108.2", "url": "https://www.ensembl.org/id/ENSBTAP00000103108.2" } ] } }, { "isoform_ac": "E1BHZ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6/entry#E1BHZ6-1", "sequence": { "sequence": "MRSFKALQNSLSRAGSHCRRGGWGHLSQNPLLTWGVRHHLSEAAAQGKETPHSHQTQHQDQRSREQFSGSCPSPLSLPPNSDSSESGMLSRLGDLLFYTIGEGQERIPIHKFTTALKATGLQTSDPRLRDCMSQMRRMVRQSNSGGLLDRDLFRKCVSSNIVLLTQAFRKKFVIPDFEEFTSHVDRIFEDAKELTGGKVAAYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHKFVGKEPSGLRYNTLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNIMGMMCLSPPLDKLGNSYRGVNFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAASSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTPSETWAEAAAEALSKENLESMV", "length": 622, "header": "tr|E1BHZ6-1|E1BHZ6_BOVIN Isoform 1 of glutaminase OS=Bos taurus OX=9913 GN=GLS2 PE=3 SV=5 CANONICAL=E1BHZ6-1" }, "locus": { "chromosome": "5", "start_pos": 56922800, "end_pos": 56910794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012233.8", "url": "https://www.ensembl.org/id/ENSBTAT00000012233.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012233.8", "url": "https://www.ensembl.org/id/ENSBTAP00000012233.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-210500", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-210500", "resource": "Reactome", "description": "Glutamate Neurotransmitter Release Cycle" }, { "id": "R-BTA-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-BTA-8964539", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8964539", "resource": "Reactome", "description": "Glutamate and glutamine metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ6", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "glutamine metabolic process", "id": "GO:0006541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006541", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ6", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6" } ], "pmid": "" }, { "name": "glutamate biosynthetic process", "id": "GO:0006537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006537", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ6", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6" } ], "pmid": "" }, { "name": "L-glutamine catabolic process", "id": "GO:0006543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006543", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ6", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glutaminase activity", "id": "GO:0004359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004359", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ6", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15889", "name": "", "equation": "L-glutamine + H2O = L-glutamate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BHZ6-1", "F1MVC0-1", "A0A3Q1NBH6-1" ], "evidence": [ { "id": "15889", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15889" } ] }, { "id": "R-BTA-70609", "name": "glutamine + H2O => glutamate + NH4+ (GLS)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-113522" ], "output_participant_list": [], "enzyme_list": [ "E1BHZ6-1" ], "evidence": [ { "id": "R-BTA-70609", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70609" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113522", "participant_name": "L-Gln [mitochondrial matrix]", "crossref": [ { "id": "58359", "database": "ChEBI", "url": "" }, { "id": "ZINC000001532526", "database": "ZINC", "url": "" }, { "id": "C00064", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1NBH6", "gene_name": "GLS", "activity": [ { "ec_number": "3.5.1.2", "activity": "L-glutamine + H2O = L-glutamate + NH4(+).", "evidence": [ { "id": "A0A3Q1NBH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBH6" } ] }, { "ec_number": "3.5.1.2", "activity": "", "evidence": [ { "id": "A0A3Q1NBH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBH6" } ] } ] }, { "uniprot_ac": "E1BHZ6", "gene_name": "GLS2", "activity": [ { "ec_number": "3.5.1.2", "activity": "L-glutamine + H2O = L-glutamate + NH4(+).", "evidence": [ { "id": "E1BHZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6" } ] }, { "ec_number": "3.5.1.2", "activity": "", "evidence": [ { "id": "E1BHZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6" } ] } ] }, { "uniprot_ac": "F1MVC0", "gene_name": "CAD", "activity": [ { "ec_number": "6.3.4.16", "activity": "hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+).", "evidence": [ { "id": "F1MVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC0" } ] }, { "ec_number": "2.1.3.2", "activity": "carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+).", "evidence": [ { "id": "F1MVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC0" } ] }, { "ec_number": "3.5.2.3", "activity": "(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate + H(+).", "evidence": [ { "id": "F1MVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC0" } ] }, { "ec_number": "6.3.5.5", "activity": "hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+).", "evidence": [ { "id": "F1MVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC0" } ] }, { "ec_number": "3.5.1.2", "activity": "L-glutamine + H2O = L-glutamate + NH4(+).", "evidence": [ { "id": "F1MVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC0" } ] }, { "ec_number": "2.1.3.2", "activity": "", "evidence": [ { "id": "F1MVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC0" } ] }, { "ec_number": "6.3.4.16", "activity": "", "evidence": [ { "id": "F1MVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC0" } ] }, { "ec_number": "6.3.5.5", "activity": "", "evidence": [ { "id": "F1MVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC0" } ] }, { "ec_number": "3.5.2.3", "activity": "", "evidence": [ { "id": "F1MVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC0" } ] }, { "ec_number": "3.5.1.2", "activity": "", "evidence": [ { "id": "F1MVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHZ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 622, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHZ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHZ6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHZ6" }, { "id": "PF17959", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17959" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glutaminase EF-hand", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 175, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.1.2", "ec_name": "L-glutamine + H2O = L-glutamate + NH4(+).", "evidence": [ { "id": "3.5.1.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2" }, { "id": "3.5.1.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.1.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 328, "end_pos": 330 }, { "start_pos": 504, "end_pos": 506 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BL46-1", "uniprot_ac": "E1BL46", "uniprot_id": "E1BL46_BOVIN", "mass": { "chemical_mass": 36116.0, "monoisotopic_mass": 36116.0 }, "refseq": {}, "gene_names": [ { "name": "CA11", "type": "recommended", "evidence": [ { "id": "E1BL46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL46" } ] } ], "protein_names": [ { "name": "Carbonic anhydrase-related protein 11", "type": "recommended", "evidence": [ { "id": "E1BL46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL46/entry#names_and_taxonomy" } ] }, { "name": "CA-RP XI", "type": "synonym", "evidence": [ { "id": "E1BL46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL46/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Does not have a catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S9G2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9G2#function" }, { "database": "UniProtKB", "id": "ARBA00002258", "url": "https://www.uniprot.org/uniprotkb/ARBA00002258#function" }, { "database": "UniProtKB", "id": "E1BL46", "url": "https://www.uniprot.org/uniprotkb/E1BL46#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BL46", "url": "https://www.uniprot.org/uniprotkb/E1BL46" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CA11", "url": "https://www.uniprot.org/uniprotkb/E1BL46", "locus": { "chromosome": "18", "start_pos": 55279515, "end_pos": 55285506, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006757", "url": "https://www.ensembl.org/id/ENSBTAG00000006757" } ] } } ], "crossref": [ { "id": "E1BL46", "url": "https://alphafold.ebi.ac.uk/entry/E1BL46", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006757", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006757", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03121", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03121", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "326334", "url": "https://www.ncbi.nlm.nih.gov/gene/326334", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HKNQNAC", "url": "https://omabrowser.org/oma/group/HKNQNAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BL46", "url": "https://www.orthodb.org/?gene=E1BL46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952:SF93", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952:SF93", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S9G2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9G2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL46", "url": "https://www.uniprot.org/uniprotkb/E1BL46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL46-1", "url": "https://www.uniprot.org/uniprotkb/E1BL46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNLSAATRGPNGLAILSLFVNVAGSSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNGRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGAPHGR", "length": 328, "header": "tr|E1BL46-1|E1BL46_BOVIN Isoform 1 of Carbonic anhydrase-related protein 11 OS=Bos taurus OX=9913 GN=CA11 PE=3 SV=3 CANONICAL=E1BL46-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S9G2-1", "url": "https://www.uniprot.org/uniprotkb/E1BL46/entry#A0AAA9S9G2-1", "sequence": { "sequence": "MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNLSAATRGPNGLAILSLFVNVAGSSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNGRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHGMMQSPTPSTSWSNPPMCLPLMFQYDAVQPLPCCFCVTQPPELSLALSPFVSKWYSPPSCPRPLQVRDLQFFTACNLQLGV", "length": 401, "header": "tr|A0AAA9S9G2-1|E1BL46_BOVIN Computationally mapped isoform of Carbonic anhydrase-related protein 11 OS=Bos taurus OX=9913 GN=CA11 PE=3 SV=1 CANONICAL=E1BL46-1" }, "locus": { "chromosome": "18", "start_pos": 55285152, "end_pos": 55280189, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125281.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125281.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078771.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078771.1" } ] } }, { "isoform_ac": "E1BL46-1", "url": "https://www.uniprot.org/uniprotkb/E1BL46/entry#E1BL46-1", "sequence": { "sequence": "MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNLSAATRGPNGLAILSLFVNVAGSSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNGRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGAPHGR", "length": 328, "header": "tr|E1BL46-1|E1BL46_BOVIN Isoform 1 of Carbonic anhydrase-related protein 11 OS=Bos taurus OX=9913 GN=CA11 PE=3 SV=3 CANONICAL=E1BL46-1" }, "locus": { "chromosome": "18", "start_pos": 55285152, "end_pos": 55279611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008890.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008890.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008890.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008890.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BBM0-1", "protein_name": "Carbonic anhydrase-related protein 10 isoform X1", "gene_name": "ca10b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPHVWEFVLILNINVIFVEAQPVSSKLHDGWWAYKDVVQGSFIPVPSFWGLVNTAWNLCAIGKRQSPVNIETSRMIFDPFLNPLRLNAGQRKVSGTMYNTGRHVSLRPDKSHLVNISGGPLSYSYRLEEIRLHFGSEDNRGSEHLLNGQAFPGEVQLIHYNQDLYLNYSDAVRSPNGIAVVSIFMKISEPTNVFLNRMLNRETVTRITYKHDAYLLMGLNIEELYPETSRFITYEGSITIPPCLETATWILMNKPIYISQIEMQSLRLLSQNQPSQIFLSMGDNMRPTQTLHQRCIRTNINFSQRRDCPNNRMLRPQYRVNEWLLK", "length": 326 }, "evidence": [ { "id": "E1BL46", "url": "https://omabrowser.org/oma/group/E1BL46/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O70354-1", "protein_name": "Carbonic anhydrase-related protein 11", "gene_name": "Ca11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGAARLSAPQALVLWAALGAAAHIGPAPDPEDWWSYKENLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPASRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHEGFSAEVQLIHFNQELYGNLSAASRGPNGLAILSLFVNVAGSSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNGRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGGPHGR", "length": 328 }, "evidence": [ { "id": "E1BL46", "url": "https://omabrowser.org/oma/group/E1BL46/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O75493-1", "protein_name": "Carbonic anhydrase-related protein 11", "gene_name": "CA11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGVPHGR", "length": 328 }, "evidence": [ { "id": "E1BL46", "url": "https://omabrowser.org/oma/group/E1BL46/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q811X3-1", "protein_name": "Carbonic anhydrase-related protein 11", "gene_name": "Ca11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGAARLSAPQALVLWAALGAAAHIGPAPDPEDWWSYKENLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPASRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNLSAASRGPNGLAILSLFVNVAGSSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNGRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGGPHGR", "length": 328 }, "evidence": [ { "id": "E1BL46", "url": "https://omabrowser.org/oma/group/E1BL46/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9W3P7-1", "protein_name": "4.2.1.-", "gene_name": "CARPA", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPSPGHHTSFCCSTAGFIACSAIVLLCSSEVLSSWEEWWTYDGISGPSFWGLINPQWNMCNKGRRQSPIDVVPDKLLFDPYLRPLHIDKHKVSGTLHNTGQSLVFRVDKDTKQHVNISGGPLAYRYQFEEIYIHYGTENVRGSEHFIQGYSFPGEIQIYGFNKELYHNMSEAQHKSQGIVGLSLMVQIGETPNPELRIITSTFNKVLYRGFSTPIRHISVRSLLPNTDHYITYEGSTTHPGCWESTVWIIVNKPIYITKQELYQLRRLMQGSESTPKAPLGNNARPVQSLHHRTVRTNIDFKRNKNQYACPSMYKDMYYRANRWSPDTGLLIR", "length": 333 }, "evidence": [ { "id": "E1BL46", "url": "https://omabrowser.org/oma/group/E1BL46/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BL46", "url": "https://www.uniprot.org/uniprotkb/E1BL46" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "E1BL46", "url": "https://www.uniprot.org/uniprotkb/E1BL46" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BL46", "url": "https://www.uniprot.org/uniprotkb/E1BL46" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "E1BL46", "url": "https://www.uniprot.org/uniprotkb/E1BL46" } ], "pmid": "" }, { "name": "hydro-lyase activity", "id": "GO:0016836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016836", "evidence": [ { "database": "UniProtKB", "id": "E1BL46", "url": "https://www.uniprot.org/uniprotkb/E1BL46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BL46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL46" }, { "id": "PS51144", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-carbonic anhydrase", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 303, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 260, "end_pos": 262 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJF9-1", "uniprot_ac": "E1BJF9", "uniprot_id": "E1BJF9_BOVIN", "mass": { "chemical_mass": 18688.0, "monoisotopic_mass": 18688.0 }, "refseq": {}, "gene_names": [ { "name": "LOC104968478", "type": "recommended", "evidence": [ { "id": "E1BJF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF9" } ] } ], "protein_names": [ { "name": "Serum amyloid A protein", "type": "recommended", "evidence": [ { "id": "E1BJF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Major acute phase reactant. Apolipoprotein of the HDL complex.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SDM7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDM7#function" }, { "database": "UniProtKB", "id": "RU000539", "url": "https://www.uniprot.org/uniprotkb/RU000539#function" }, { "database": "UniProtKB", "id": "E1BJF9", "url": "https://www.uniprot.org/uniprotkb/E1BJF9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJF9", "url": "https://www.uniprot.org/uniprotkb/E1BJF9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC104968478", "url": "https://www.uniprot.org/uniprotkb/E1BJF9", "locus": {} } ], "crossref": [ { "id": "E1BJF9", "url": "https://alphafold.ebi.ac.uk/entry/E1BJF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000022395", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000022395", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "104968478", "url": "https://www.ncbi.nlm.nih.gov/gene/104968478", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BJF9", "url": "https://www.orthodb.org/?gene=E1BJF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23424:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23424:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SDM7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDM7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJF9", "url": "https://www.uniprot.org/uniprotkb/E1BJF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJF9-1", "url": "https://www.uniprot.org/uniprotkb/E1BJF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTCKDFPRAPVQLFSSRPTSQGWLSINIATTPQQAGTSRSDPLGISTMKLFTGLILCSLVLGVHSQWMSFFGEAYEGAKDMWRAYSDMREANYKDADKYFHARGNYDAARRGPGGAWAAKVISDARENIQRFTGQGQEDSRADQAANEWGRSGKDPNHFRPAGLPDKY", "length": 168, "header": "tr|E1BJF9-1|E1BJF9_BOVIN Isoform 1 of Serum amyloid A protein OS=Bos taurus OX=9913 GN=LOC104968478 PE=3 SV=3 CANONICAL=E1BJF9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SDM7-1", "url": "https://www.uniprot.org/uniprotkb/E1BJF9/entry#A0AAA9SDM7-1", "sequence": { "sequence": "MRTTIGVHTMKLFTGLILCSLVLGVHSQWMSFFGEAYEGAKDMWRAYSDMREANYKDADKYFHARGNYDAARRGPGGAWAAKVISDARENIQRFTDPLFKGTTSGQGQEDSRADQAANEWGRSGKDPNHFRPAGLPDKY", "length": 139, "header": "tr|A0AAA9SDM7-1|E1BJF9_BOVIN Computationally mapped isoform of Serum amyloid A protein OS=Bos taurus OX=9913 GN=LOC104968478 PE=3 SV=1 CANONICAL=E1BJF9-1" }, "locus": { "chromosome": "29", "start_pos": 26443604, "end_pos": 26440405, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132967.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132967.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080459.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080459.1" } ] } }, { "isoform_ac": "E1BJF9-1", "url": "https://www.uniprot.org/uniprotkb/E1BJF9/entry#E1BJF9-1", "sequence": { "sequence": "MTCKDFPRAPVQLFSSRPTSQGWLSINIATTPQQAGTSRSDPLGISTMKLFTGLILCSLVLGVHSQWMSFFGEAYEGAKDMWRAYSDMREANYKDADKYFHARGNYDAARRGPGGAWAAKVISDARENIQRFTGQGQEDSRADQAANEWGRSGKDPNHFRPAGLPDKY", "length": 168, "header": "tr|E1BJF9-1|E1BJF9_BOVIN Isoform 1 of Serum amyloid A protein OS=Bos taurus OX=9913 GN=LOC104968478 PE=3 SV=3 CANONICAL=E1BJF9-1" }, "locus": { "chromosome": "29", "start_pos": 26443550, "end_pos": 26440405, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030327.5", "url": "https://www.ensembl.org/id/ENSBTAT00000030327.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030311.5", "url": "https://www.ensembl.org/id/ENSBTAP00000030311.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "high-density lipoprotein particle", "id": "GO:0034364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034364", "evidence": [ { "database": "UniProtKB", "id": "E1BJF9", "url": "https://www.uniprot.org/uniprotkb/E1BJF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "acute-phase response", "id": "GO:0006953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006953", "evidence": [ { "database": "UniProtKB", "id": "E1BJF9", "url": "https://www.uniprot.org/uniprotkb/E1BJF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJF9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 168, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJF9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJF9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJ14-1", "uniprot_ac": "E1BJ14", "uniprot_id": "E1BJ14_BOVIN", "mass": { "chemical_mass": 82854.0, "monoisotopic_mass": 82854.0 }, "refseq": { "ac": "XP_005212599", "name": "stonin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212599" }, "gene_names": [ { "name": "STON1", "type": "recommended", "evidence": [ { "id": "E1BJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ] }, { "name": "STON1", "type": "synonym", "evidence": [ { "id": "XP_005212599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212599" } ] } ], "protein_names": [ { "name": "Stonin-1", "type": "recommended", "evidence": [ { "id": "E1BJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ14/entry#names_and_taxonomy" } ] }, { "name": "stonin-1", "type": "synonym", "evidence": [ { "id": "XP_005212599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212599" } ] } ], "function": [ { "annotation": "May be involved in the endocytic machinery.", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14#function" }, { "database": "UniProtKB", "id": "PIRNR037099", "url": "https://www.uniprot.org/uniprotkb/PIRNR037099#function" }, { "database": "UniProtKB", "id": "ARBA00059680", "url": "https://www.uniprot.org/uniprotkb/ARBA00059680#function" }, { "database": "UniProtKB", "id": "A0AAA9SE16", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE16#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "STON1", "url": "https://www.uniprot.org/uniprotkb/E1BJ14", "locus": { "chromosome": "11", "start_pos": 30892686, "end_pos": 30865426, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004168", "url": "https://www.ensembl.org/id/ENSBTAG00000004168" } ] } } ], "crossref": [ { "id": "E1BJ14", "url": "https://alphafold.ebi.ac.uk/entry/E1BJ14", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004168", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004168", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100140704", "url": "https://www.ncbi.nlm.nih.gov/gene/100140704", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NIMVHFP", "url": "https://omabrowser.org/oma/group/NIMVHFP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJ14", "url": "https://www.orthodb.org/?gene=E1BJ14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10529", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10529", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00928", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00928", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005212599", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212599", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SE16", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SE16-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ14-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSTNPGNWVTFDDDPTFQSSQKSKNFPLENQGICRPNGLKLNLSGAKEFPSGSSSTSSTPLSSPIIDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSNSPLTTATGSSSLATKPTCFSQASLPSDHSCIHPASKVGLADEMSPHQAEGFQSDTPQFQYFREDCAFSSPFWKDEGSASQLTFDPPGSRKIFPSRDKEVPVDQKGLNQCSLNYICEKLEYLQSAENQDSFGNLSMQCLYAEDPASSFVPHMLFRSQPKAGWSFMMRIPEKKNMMSSRQWGPIFLKVLPGGILQMYYEKGLEKPFKELQLDPYCRLSEPKVENFSMAGKIHTVKIEHVSYTEKRKYHSKTEVVHEPDIEQMLKLGSTEYHDFLDFLTTVEEELIRLPAVSKPKKNYEEQEIFLEIVDNFWGKITKEEGKLVESAVITQISCLCFVNGNTECFLTLNDHELQKRNERYFEKDPEKKGIDMLDYHFHKCVKAQEFEQSRIIKFVPLDACRFELMRFKTSHSGEDLPFSLKSVVVVQGAYVELQAFVNMAPLVQRPSHAGSWRSCDNIMIHFPVPSQWIKALWTMNLQRQKSLKAKMNRRACLGSLHELESEPVIQVTVGSAKYESAYRAVVWKIDRLPDKNSSPDHPHCLSYKLELGSDQEIPSDWYPFATIQFGILDTTASRTEVRSLGVESDVQPQKHIHHRACYNIQVEIEKKWIKIDGEDPDKAGDCVTQ", "length": 732, "header": "tr|E1BJ14-1|E1BJ14_BOVIN Isoform 1 of Stonin-1 OS=Bos taurus OX=9913 GN=STON1 PE=3 SV=3 CANONICAL=E1BJ14-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SE16-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ14/entry#A0AAA9SE16-1", "sequence": { "sequence": "MSRGSHLGCTLWRNRLFSETTYLIHWQDHSLIPKMCSTNPGNWVTFDDDPTFQSSQKSKNFPLENQGICRPNGLKLNLSGAKEFPSGSSSTSSTPLSSPIIDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSNSPLTTATGSSSLATKPTCFSQASLPSDHSCIHPASKVGLADEMSPHQAEGFQSDTPQFQYFREDCAFSSPFWKDEGSASQLTFDPPGSRKIFPSRDKEVPVDQKGLNQCSLNYICEKLEYLQSAENQDSFGNLSMQCLYAEDPASSFVPHMLFRSQPKAGWSFMMRIPEKKNMMSSRQWGPIFLKVLPGGILQMYYEKGLEKPFKELQLDPYCRLSEPKVENFSMAGKIHTVKIEHVSYTEKRKYHSKTEVVHEPDIEQMLKLGSTEYHDFLDFLTTVEEELIRLPAVSKPKKNYEEQEIFLEIVDNFWGKITKEEGKLVESAVITQISCLCFVNGNTECFLTLNDHELQKRNERYFEKDPEKKGIDMLDYHFHKCVKAQEFEQSRIIKFVPLDACRFELMRFKTSHSGEDLPFSLKSVVVVQGAYVELQAFVNMAPLVQRPSHAGSWRSCDNIMIHFPVPSQWIKALWTMNLQRQKSLKAKMNRRACLGSLHELESEPVIQVTVGSAKYESAYRAVVWKIDRLPDKNSSPDHPHCLSYKLELGSDQEIPSDWYPFATIQFGILDTTASRTEVRSLGVESDVQPQKHIHHRACYNIQVEIEKKWIKIDGEDPDKAGDCVTQ", "length": 766, "header": "tr|A0AAA9SE16-1|E1BJ14_BOVIN Computationally mapped isoform of Stonin-1 OS=Bos taurus OX=9913 GN=STON1 PE=3 SV=1 CANONICAL=E1BJ14-1" }, "locus": { "chromosome": "11", "start_pos": 30889725, "end_pos": 30865430, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128147.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128147.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082062.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082062.1" } ] } }, { "isoform_ac": "E1BJ14-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ14/entry#E1BJ14-1", "sequence": { "sequence": "MCSTNPGNWVTFDDDPTFQSSQKSKNFPLENQGICRPNGLKLNLSGAKEFPSGSSSTSSTPLSSPIIDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSNSPLTTATGSSSLATKPTCFSQASLPSDHSCIHPASKVGLADEMSPHQAEGFQSDTPQFQYFREDCAFSSPFWKDEGSASQLTFDPPGSRKIFPSRDKEVPVDQKGLNQCSLNYICEKLEYLQSAENQDSFGNLSMQCLYAEDPASSFVPHMLFRSQPKAGWSFMMRIPEKKNMMSSRQWGPIFLKVLPGGILQMYYEKGLEKPFKELQLDPYCRLSEPKVENFSMAGKIHTVKIEHVSYTEKRKYHSKTEVVHEPDIEQMLKLGSTEYHDFLDFLTTVEEELIRLPAVSKPKKNYEEQEIFLEIVDNFWGKITKEEGKLVESAVITQISCLCFVNGNTECFLTLNDHELQKRNERYFEKDPEKKGIDMLDYHFHKCVKAQEFEQSRIIKFVPLDACRFELMRFKTSHSGEDLPFSLKSVVVVQGAYVELQAFVNMAPLVQRPSHAGSWRSCDNIMIHFPVPSQWIKALWTMNLQRQKSLKAKMNRRACLGSLHELESEPVIQVTVGSAKYESAYRAVVWKIDRLPDKNSSPDHPHCLSYKLELGSDQEIPSDWYPFATIQFGILDTTASRTEVRSLGVESDVQPQKHIHHRACYNIQVEIEKKWIKIDGEDPDKAGDCVTQ", "length": 732, "header": "tr|E1BJ14-1|E1BJ14_BOVIN Isoform 1 of Stonin-1 OS=Bos taurus OX=9913 GN=STON1 PE=3 SV=3 CANONICAL=E1BJ14-1" }, "locus": { "chromosome": "11", "start_pos": 30889725, "end_pos": 30875530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005457.8", "url": "https://www.ensembl.org/id/ENSBTAT00000005457.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005457.6", "url": "https://www.ensembl.org/id/ENSBTAP00000005457.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-BTA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BRM0-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCSTNPANWVTFDDEPLFQSPQKLVHNQSSCKANGLKLNLSTVHESSSRSSSTGSTPLSSPVVDFYLSPGPPSNSPLTTPTREYPGIQKHGIHVLYPIPEWPPNTNLPSPGVCSSLASQKPSSLLLTNDGSVKTSVSKSVDEGNADLQGGCDKSEESSAVGQFPYFQTDCGFSSPFWKEGCSLSTSPANINVYRKDKVLDKGTCHSTEKEICHDQKSLNQGSFSYICERLEHLQADGSDAVGSLPISSSHEWHKDSSAVPHGLFRSRKADGWPFMLRIPEKKNMMSSRQWGPIYLRVLAGGILQMYYEKGLEKPFKEFQLQPHCKLSEPKLESYNVSGKIHTVKIECVSYTEKRRYHPKVEVIHEPEVEQMLKLGTTDYNDFTDFLVTVEEELMKLPTTSKQRRNYEEQEMTLEIVDNFWGKVTKGEGKLVESAVITHVYCLCFVNGGTDCFLTLNDLELQKRDECYFEKEAEKKWISILDCHFHNCVKMQEFEQLRIIKFTPPDACRLELMRFRTQYHGEDLPFSLKATVVVQGAYVELQAFINMSSTALIPTRLPSVKCCENVMIHFPVPAQWVKALWTMNLQRQKSLKAKMNRRTCLGSLHEIESDPVIQVSIGTAKYESAYRAVVWKIDRLPDKNSSADHPHSLSYKLELGSDQEIPSDWYPFATVQFIVHDTCASGTEVKSLGLESDVQPQKHVIQKAFYNCQVEIEKKWIRLDGEDPDKAGNCLMQ", "length": 732 }, "evidence": [ { "id": "E1BJ14", "url": "https://omabrowser.org/oma/group/E1BJ14/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3H5R3-1", "protein_name": "Stonin-1", "gene_name": "Ston1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCSTNPGSWVTFDEDPAFQSSQKAKDFSLETQSVCRPNGLKLNLPGLRDFPSTSSSASSTPLSSPMVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGSHVLYPIPECSSSSPPKTAGGTGPSLSLTKPTCSPQASLPSDHLGAQLTPKAGLEDDASPQRAPSETLQFEYFRDDCAFSNPFWKDEGSSSQFPFDSLAGRKPFSSRDKEVSMDQKSLNQCSLNYICEKLEHLQSAETQDPPGNLSRQSLSAGDTSPSFVPHTLFRSQPRDGWSFMLRIPEKKNMMSSRQWGPIFLKVLPGGILQMYYEQGLEKPFKEFQLDPHCRLSEPKLENFSMAGKIHTVKVEHVSYSEKRKYHSKTEVVREPEVEQMLKLGSTDHGDFLEFLTTVEEELIKLPIVAKPRKNYEEQEIYLDIVDNFWGKVTKGDGKLVESAVITQISCLCFVNGPAQCFLTLNDLELQKRDECCFEKEPDKRGIDILNYHFHSCVKAEEFRQSRVIKFVPLDACRFELMRFKTSYEGDELPFSVKSVVAVQGAYVELQAFVNMTPGLQRSPHASSLRCCENIMIHFPVPAQWIKALWTRNLQRQKSLKAKMNRRACLGSLQEPESEPIIQVTVGSAKYESAYRAVVWKIDRLPDKNSSPDQPHCLSYKLELGSDQEIPSDWYPFATVQFSMPEASASGTEVRSLGVDSDVQPQKHVCQRACYSIQVEIERKWIQIDGEDPDKAGDCVTQ", "length": 731 }, "evidence": [ { "id": "E1BJ14", "url": "https://omabrowser.org/oma/group/E1BJ14/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCSTNPGKWVTFDDDPAVQSSQKSKNFPLENQGVCRPNGLKLNLPGLREFPSGSSSTSSTPLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDSPLAISGGESSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQSDDLPQFQYFREDCAFSSPFWKDEGSDSHFTLDPPGSKKMFSSRNKEMPIDQKSLNKCSLNYICEKLEHLQSAENQDSLRSLSMHCLCAEENASSFVPHTLFRSQPKSGWSFMLRIPEKKNMMSSRQWGPIFLKVLPGGILQMYYEQGLEKPFKEIQLDPYCRLSEPKVENFSVAGKIHTVKIEHVSYTEKRKYHSKTEVVHEPDIEQMLKLGSTSYHDFLDFLTTVEEELMKLPAVSKPKKNYEEQEISLEIVDNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLNDLELPKRDESYYEKDSEKKGIDILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFKTLYNGDNLPFSLKSVVVVQGAYVELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQWIKALWTMNLQRQKSLKAKMNRRACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSLDHPHCLSYKLELGSDQEIPSDWYPFATVQFSVPDTCASRTEVRSLGVESDVQPQKHVQQRACYNIQVEIEKKWIKIDGEDPDKIGDCITQ", "length": 735 }, "evidence": [ { "id": "E1BJ14", "url": "https://omabrowser.org/oma/group/E1BJ14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" }, { "name": "AP-2 adaptor complex", "id": "GO:0030122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030122", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cargo adaptor activity", "id": "GO:0140312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140312", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" }, { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "E1BJ14", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJ14-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 732, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJ14-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJ14" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" }, { "id": "PS51072", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51072" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MHD", "eco_id": "ECO_0000259", "start_pos": 408, "end_pos": 712, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ14" }, { 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"categories": [ "Protein Classification" ] }, { "id": "IPR013519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053792", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053792", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100140050", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140050", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "bta:338035", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:338035", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M2K1", "url": "https://www.orthodb.org/?gene=A0A3Q1M2K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BFX5", "url": "https://www.orthodb.org/?gene=E1BFX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MUF3", "url": "https://www.orthodb.org/?gene=F1MUF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10125", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10125", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10125:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10125:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220:SF79", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220:SF79", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00864", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00864", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01839", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01839", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-139853", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-139853", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-216083", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-216083", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-418346", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418346", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001411997", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411997", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M2K1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2K1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIB8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIB8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6P2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6P2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX77", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX77-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFX5", "url": "https://www.uniprot.org/uniprotkb/E1BFX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFX5-1", "url": "https://www.uniprot.org/uniprotkb/E1BFX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MUF3", "url": "https://www.uniprot.org/uniprotkb/F1MUF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MUF3-1", "url": "https://www.uniprot.org/uniprotkb/F1MUF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLFHSLLCVTSLAPLAAFNVDVVRTWVTPEGGDPYVLSSLLHQDSSTKKTWLLVTSPRTSRTAKPLHQCSLIQDELHCQPVEHIPIPKGRYQGVTAVQNHHGVLVCIQVPTRQPHSLSSELTGNCSLLTPDLRPRAQVYFSNLERFLDPDASVDAGACRRDKKDSTENTARRRRDLKVEEEEEEEEAAGTEIAIVLDGSGSIDPPDFQKAKDFIYDMMKNFYTKCFECRFAVVQYGEVIQTELDLLDSQDVRASLDRVKNISQVGKITKTASAMQHVLDNIFTPNQGSRAKASKVMVVLTDGEIFQDPLNLTTVINSPKMHGVERFAIGVGEAFNKSKAYHELKLIASDPDEDHAFKVTNYMALDGLLNKLQESIIRVEGTVGDALHYQLAQVGFSAQILDKGQVLLGTVGAFDWSGGALLYDTHRCNGIFLNQTAVDTKSAQYGYLGYSVAVLHKAHGLSYVAGAPRHKQQGAVFELQKVGRETNNFMPVLEGEQLGSYFGSELCPVDVDMDGITDLLLVAAPFYHIQGEEGRVYMYRVNKQDGSFSLARRLSGHPRLTYARFGFAMATVGDISQDGLTDVAIGAPLEDFEADNGAGFGSVYIYNGRSTNQLADLSATQPQRIRASAVAPGLQYFGTSVAGGLDFNGDGLADITVGALGRAAVLRSRPVVHLKVSMNFTPKALPIGFSSSVNVCLCFEINSTTLAAESGLGETSLNFTLDVDVVKQRKRLQHSDKRMDQSSLREWGRGPLLCESFLLIPTDGDLCQEDCFSNITIKVSYHLQTPEGRMDQPQPILDFYAEPSAIFQLPYEKNCKNKLFCVAELQLATTISQQELVVGLTKELTMNISLTNSGEDSYMTSMAVNFPRNLQFKRIQKPPSPDIQCGDPKPIASVLVMKCKIGHPILKRSSANFSLVWQLEESAFPNRTANITVMVTNSNERRSLVNKTHSLQIKHAFIAVLPKPSVMYMNTSQGSSHHKEFLFNIHGENLFGAEFQLQICVPVKLQGFQFLTVTNLTKIQAHTVCTQALERVCGSDLVQLVEEWHSVSCKVTSDKENVTVAAELSLNQLKQLLRDVTELQILGEISFNKSLYEGLNTENHRTKITVILLKDEEAYSLSLIIKSSVGGLLVLIVIIVILVKCGFFKRKYRELNLESVRKDQLKSQSLLEEDN", "length": 1171, "header": "sp|E1BFX5-1|ITAE_BOVIN Isoform 1 of Integrin alpha-E OS=Bos taurus OX=9913 GN=ITGAE PE=3 SV=3 CANONICAL=E1BFX5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M2K1-1", "url": "https://www.uniprot.org/uniprotkb/E1BFX5/entry#A0A3Q1M2K1-1", "sequence": { "sequence": "MGQAGCKGLYQSLFDYKTEKYVIAKNKKVGLLYRLLQVSILTYLVVWVFLVKKCYQDTDTSLQSSIITKVKGVTFTNTSELGERLWDVADYVIPPQGENVFFVITNLVVTPNQRQETCAESASVPDALCYEDSDCPPGEPVAAGNGVRTGRCLREGSAQKGTCEIFAWCPVETRSRPTKPLLGEAKDFTVYIKNFIRFPKFNFSKTNVLDTTDRTFLKSCKFSPENPYCPIFRLGSVVSWTGSNFQEIAVQGGVIGIQIEWDCDLDKAPSECYPRYYFNRLDNRFSGNSISSGYNFRFAKYYRDAAGVEFRTLFKAYGIRFDVMVNGKAGKFNIIPTIINVGSGVALMGVGSFFCDLVLIYFIKKSHFYRDKKYEEVRSGHQGNGKVNVEQLQSLQTVEA", "length": 400, "header": "tr|A0A3Q1M2K1-1|ITAE_BOVIN Computationally mapped isoform of Integrin alpha-E OS=Bos taurus OX=9913 GN=ITGAE PE=3 SV=1 CANONICAL=E1BFX5-1" }, "locus": { "chromosome": "19", "start_pos": 24384507, "end_pos": 24372129, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072471.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072471.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067651.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067651.1" } ] } }, { "isoform_ac": "A0AAA9SIB8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFX5/entry#A0AAA9SIB8-1", "sequence": { "sequence": "MGQAGCKGLYQSLFDYKTEKYVIAKNKKVGLLYRLLQVSILTYLVVWVFLVKKCYQDTDTSLQSSIITKVKGVTFTNTSELGERLWDVADYVIPPQGENVFFVITNLVVTPNQRQETCAESASVPDALCYEDSDCPPGEPVAAGNGVRTGRCLREGSAQKGTCEIFAWCPVETRSRPTKPLLGEAKDFTVYIKNFIRFPKFNFSKTNVLDTTDRTFLKSCKFSPENPYCPIFRLGSVVSWTGSNFQEIAVQGGVIGIQIEWDCDLDKAPSECYPRYYFNRLDNRFSGNSISSGYNFRFAKYYRDAAGVEFRTLFKAYGIRFDVMVNGKAGKFNIIPTIINVGSGVALMGVGSFFCDLVLIYFIKKSHFYRDKKYEEVRAASPMLLSDVDILELPEPQDGGGCADRWPAGHPSLERCPGQPGKGGSPGACFASASLCAPGQAPGPFWA", "length": 447, "header": "tr|A0AAA9SIB8-1|ITAE_BOVIN Computationally mapped isoform of Integrin alpha-E OS=Bos taurus OX=9913 GN=ITGAE PE=3 SV=1 CANONICAL=E1BFX5-1" }, "locus": { "chromosome": "19", "start_pos": 24384507, "end_pos": 24372833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106259.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106259.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083490.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083490.1" } ] } }, { "isoform_ac": "A0AAA9T6P2-1", "url": "https://www.uniprot.org/uniprotkb/E1BFX5/entry#A0AAA9T6P2-1", "sequence": { "sequence": "MGQAGCKGLYQSLFDYKTEKYVIAKNKKVGLLYRLLQVSILTYLVVWVFLVKKCYQDTDTSLQSSIITKVKGVTFTNTSELGERLWDVADYVIPPQGENVFFVITNLVVTPNQRQETCAESASVPDALCYEDSDCPPGEPVAAGNGVRTGRCLREGSAQKGTCEIFAWCPVETRSRPTKPLLGEAKDFTVYIKNFIRFPKFNFSKTNVLDTTDRTFLKSCKFSPENPYCPIFRLGSVVSWTGSNFQEIAVQGGVIGIQIEWDCDLDKAPSECYPRYYFNRLDNRFSGNSISSGYNFRFAKYYRDAAGVEFRTLFKAYGIRFDVMVNGKAGKFNIIPTIINVGSGVALMGVGSFFCDLVLIYFIKKSHFYRDKKYEEVRDLEVLAQMAESSQQSVAPDAAGLAEQPEVQDEGGAQKENGCVCGQLLQPARAASPMLLSDVDILELPEPQDGGGCADRWPAGHPSLERCPGQPGKGGSPGACFASASLCA", "length": 488, "header": "tr|A0AAA9T6P2-1|ITAE_BOVIN Computationally mapped isoform of Integrin alpha-E OS=Bos taurus OX=9913 GN=ITGAE PE=3 SV=1 CANONICAL=E1BFX5-1" }, "locus": { "chromosome": "19", "start_pos": 24384507, "end_pos": 24372863, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126843.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126843.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093561.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093561.1" } ] } }, { "isoform_ac": "A0ABI0NX77-1", "url": "https://www.uniprot.org/uniprotkb/E1BFX5/entry#A0ABI0NX77-1", "sequence": { "sequence": "MGQAGCKGLYQSLFDYKTEKYVIAKNKKVGLLYRLLQVSILTYLVVWVFLVKKCYQDTDTSLQSSIITKVKGVTFTNTSELGERLWDVADYVIPPQGENVFFVITNLVVTPNQRQETCAESASVPDALCYEDSDCPPGEPVAAGNGVRTGRCLREGSAQKGTCEIFAWCPVETRSRPTKPLLGEAKDFTVYIKNFIRFPKFNFSKTNVLDTTDRTFLKSCKFSPENPYCPIFRLGSVVSWTGSNFQEIAVQGGVIGIQIEWDCDLDKAPSECYPRYYFNRLDNRFSGNSISSGYNFRFAKYYRDAAGVEFRTLFKAYGIRFDVMVNGKAGKFNIIPTIINVGSGVALMGVTAAHQAPPSLGFSRQEHWSGLPFPSPMHESEK", "length": 382, "header": "tr|A0ABI0NX77-1|A0ABI0NX77_BOVIN Computationally mapped isoform of P2X purinoceptor OS=Bos taurus OX=9913 GN=ITGAE PE=3 SV=1 CANONICAL=E1BFX5-1" }, "locus": { "chromosome": "19", "start_pos": 24384507, "end_pos": 24375954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152881.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152881.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105755.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105755.1" } ] } }, { "isoform_ac": "E1BFX5-1", "url": "https://www.uniprot.org/uniprotkb/E1BFX5/entry#E1BFX5-1", "sequence": { "sequence": "MWLFHSLLCVTSLAPLAAFNVDVVRTWVTPEGGDPYVLSSLLHQDSSTKKTWLLVTSPRTSRTAKPLHQCSLIQDELHCQPVEHIPIPKGRYQGVTAVQNHHGVLVCIQVPTRQPHSLSSELTGNCSLLTPDLRPRAQVYFSNLERFLDPDASVDAGACRRDKKDSTENTARRRRDLKVEEEEEEEEAAGTEIAIVLDGSGSIDPPDFQKAKDFIYDMMKNFYTKCFECRFAVVQYGEVIQTELDLLDSQDVRASLDRVKNISQVGKITKTASAMQHVLDNIFTPNQGSRAKASKVMVVLTDGEIFQDPLNLTTVINSPKMHGVERFAIGVGEAFNKSKAYHELKLIASDPDEDHAFKVTNYMALDGLLNKLQESIIRVEGTVGDALHYQLAQVGFSAQILDKGQVLLGTVGAFDWSGGALLYDTHRCNGIFLNQTAVDTKSAQYGYLGYSVAVLHKAHGLSYVAGAPRHKQQGAVFELQKVGRETNNFMPVLEGEQLGSYFGSELCPVDVDMDGITDLLLVAAPFYHIQGEEGRVYMYRVNKQDGSFSLARRLSGHPRLTYARFGFAMATVGDISQDGLTDVAIGAPLEDFEADNGAGFGSVYIYNGRSTNQLADLSATQPQRIRASAVAPGLQYFGTSVAGGLDFNGDGLADITVGALGRAAVLRSRPVVHLKVSMNFTPKALPIGFSSSVNVCLCFEINSTTLAAESGLGETSLNFTLDVDVVKQRKRLQHSDKRMDQSSLREWGRGPLLCESFLLIPTDGDLCQEDCFSNITIKVSYHLQTPEGRMDQPQPILDFYAEPSAIFQLPYEKNCKNKLFCVAELQLATTISQQELVVGLTKELTMNISLTNSGEDSYMTSMAVNFPRNLQFKRIQKPPSPDIQCGDPKPIASVLVMKCKIGHPILKRSSANFSLVWQLEESAFPNRTANITVMVTNSNERRSLVNKTHSLQIKHAFIAVLPKPSVMYMNTSQGSSHHKEFLFNIHGENLFGAEFQLQICVPVKLQGFQFLTVTNLTKIQAHTVCTQALERVCGSDLVQLVEEWHSVSCKVTSDKENVTVAAELSLNQLKQLLRDVTELQILGEISFNKSLYEGLNTENHRTKITVILLKDEEAYSLSLIIKSSVGGLLVLIVIIVILVKCGFFKRKYRELNLESVRKDQLKSQSLLEEDN", "length": 1171, "header": "sp|E1BFX5-1|ITAE_BOVIN Isoform 1 of Integrin alpha-E OS=Bos taurus OX=9913 GN=ITGAE PE=3 SV=3 CANONICAL=E1BFX5-1" }, "locus": {} }, { "isoform_ac": "F1MUF3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFX5/entry#F1MUF3-1", "sequence": { "sequence": "MRGSTQRTTELSWVFLVKKCYQDTDTSLQSSIITKVKGVTFTNTSELGERLWDVADYVIPPQGENVFFVITNLVVTPNQRQETCAESASVPDALCYEDSDCPPGEPVAAGNGVRTGRCLREGSAQKGTCEIFAWCPVETRSRPTKPLLGEAKDFTVYIKNFIRFPKFNFSKTNVLDTTDRTFLKSCKFSPENPYCPIFRLGSVVSWTGSNFQEIAVQGGVIGIQIEWDCDLDKAPSECYPRYYFNRLDNRFSGNSISSGYNFRFAKYYRDAAGVEFRTLFKAYGIRFDVMVNGKAGKFNIIPTIINVGSGVALMGVGSFFCDLVLIYFIKKSHFYRDKKYEEVRDLEVLAQMAESSQQSVAPDAAGLAEQPEVQDEGGAQKENGCVCGQLLQPARSGHQGNGKVNVEQLQSLQTVEA", "length": 417, "header": "tr|F1MUF3-1|ITAE_BOVIN Computationally mapped isoform of Integrin alpha-E OS=Bos taurus OX=9913 GN=ITGAE PE=3 SV=4 CANONICAL=E1BFX5-1" }, "locus": { "chromosome": "19", "start_pos": 24396532, "end_pos": 24372129, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020298.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020298.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020298.7", "url": "https://www.ensembl.org/id/ENSBTAP00000020298.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1015, "start_aa": "Asn", "end_pos": 1015, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1015", "evidence": [ { "id": "E1BFX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFX5#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1057, "start_aa": "Asn", "end_pos": 1057, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1057", "evidence": [ { "id": "E1BFX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFX5#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1088, "start_aa": "Asn", "end_pos": 1088, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1088", "evidence": [ { "id": "E1BFX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFX5#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2151201", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2151201", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-3299685", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3299685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "20696", "url": "https://www.rhea-db.org/rhea/20696", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SIV8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNU0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNU0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U061", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U061", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U061-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U061-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1X3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1X3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHL1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYVNSAAQSLARGGCTVTLLSGLAEVPRSVHSERTLTPGSSWRGTAPTPSQSQGPLSCETASAHGCAPMRLPETLVFALCEGPGTPRLPPTPPRQRPGRSRNAAAGFPARPAGPGPPIRGPRQAVPSRGRNAEPYHLFRGLGGGKTAALPLATRPETRSRSGGPAARAAAGETAGPLSHLRWARSTGGADHSAEHPISPELEAARAAGRGRGERSGAGSRRAQEGGAAGRAGGGAAAVVSLRRSPGHKRIVSGQRGAATRAPRGPRAASTMLSRAACSTSRRLVPALSVLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVAEEKYREALEKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPQGELLEAIKRDFGSFAKFKEKLTAVSVGVQGSGWGWLGFNKEQGRLQIAACSNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTARYTACSK", "length": 492, "header": "tr|E1BHL1-1|E1BHL1_BOVIN Isoform 1 of Superoxide dismutase [Mn], mitochondrial OS=Bos taurus OX=9913 GN=SOD2 PE=3 SV=3 CANONICAL=E1BHL1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SIV8-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1/entry#A0AAA9SIV8-1", "sequence": { "sequence": "MLSRAACSTSRRLVPALSVLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVAEEKYREALEKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPQGELLEAIKRDFGSFAKFKEKLTAVSVGVQGSGWGWLGFNKEQGRLQIAACSNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTARYTACSKKGTINTEALYCFIGFSSKRKTTPNSVTLHMAFLLSFFDWSCSEQQGPFCIWLQVFPVHQIPPHR", "length": 286, "header": "tr|A0AAA9SIV8-1|E1BHL1_BOVIN Computationally mapped isoform of Superoxide dismutase [Mn], mitochondrial OS=Bos taurus OX=9913 GN=SOD2 PE=3 SV=1 CANONICAL=E1BHL1-1" }, "locus": { "chromosome": "9", "start_pos": 95965317, "end_pos": 95954841, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102188.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102188.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083723.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083723.1" } ] } }, { "isoform_ac": "A0AAA9TNU0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1/entry#A0AAA9TNU0-1", "sequence": { "sequence": "MLSRAACSTSRRLVPALSVLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVAEEKYREALEKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPQGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTARYTACSK", "length": 162, "header": "tr|A0AAA9TNU0-1|E1BHL1_BOVIN Computationally mapped isoform of Superoxide dismutase [Mn], mitochondrial OS=Bos taurus OX=9913 GN=SOD2 PE=3 SV=1 CANONICAL=E1BHL1-1" }, "locus": { "chromosome": "9", "start_pos": 95965317, "end_pos": 95956001, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103866.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103866.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098010.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098010.1" } ] } }, { "isoform_ac": "A0AAA9U061-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1/entry#A0AAA9U061-1", "sequence": { "sequence": "MLSRAACSTSRRLVPALSVLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVAEEKYREALEKGELLEAIKRDFGSFAKFKEKLTAVSVGVQGSGWGWLGFNKEQGRLQIAACSNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTARYTACSK", "length": 183, "header": "tr|A0AAA9U061-1|E1BHL1_BOVIN Computationally mapped isoform of Superoxide dismutase [Mn], mitochondrial OS=Bos taurus OX=9913 GN=SOD2 PE=3 SV=1 CANONICAL=E1BHL1-1" }, "locus": { "chromosome": "9", "start_pos": 95965317, "end_pos": 95956001, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122495.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122495.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103957.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103957.1" } ] } }, { "isoform_ac": "A0AAA9U1X3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1/entry#A0AAA9U1X3-1", "sequence": { "sequence": "MYVNSAAQSLARGGCTVTLLSGLAEVPRSVHSERTLTPGSSWRGTAPTPSQSQGPLSCETASAHGCAPMRLPETLVFALCEGPGTPRLPPTPPRQRPGRSRNAAAGFPARPAGPGPPIRGPRQAVPSRGRNAEPYHLFRGLGGGKTAALPLATRPETRSRSGGPAARAAAGETAGPLSHLRWARSTGGADHSAEHPISPELEAARAAGRGRGQRGAATRAPRGPRAASTMLSRAACSTSRRLVPALSVLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVAEEKYREALEKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPQGELLEAIKRDFGSFAKFKEKLTAVSVGVQGSGWGWLGFNKEQGRLQIAACSNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTARYTACSK", "length": 451, "header": "tr|A0AAA9U1X3-1|E1BHL1_BOVIN Computationally mapped isoform of Superoxide dismutase [Mn], mitochondrial OS=Bos taurus OX=9913 GN=SOD2 PE=3 SV=1 CANONICAL=E1BHL1-1" }, "locus": { "chromosome": "9", "start_pos": 95966127, "end_pos": 95956001, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128895.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128895.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103312.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103312.1" } ] } }, { "isoform_ac": "E1BHL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1/entry#E1BHL1-1", "sequence": { "sequence": "MYVNSAAQSLARGGCTVTLLSGLAEVPRSVHSERTLTPGSSWRGTAPTPSQSQGPLSCETASAHGCAPMRLPETLVFALCEGPGTPRLPPTPPRQRPGRSRNAAAGFPARPAGPGPPIRGPRQAVPSRGRNAEPYHLFRGLGGGKTAALPLATRPETRSRSGGPAARAAAGETAGPLSHLRWARSTGGADHSAEHPISPELEAARAAGRGRGERSGAGSRRAQEGGAAGRAGGGAAAVVSLRRSPGHKRIVSGQRGAATRAPRGPRAASTMLSRAACSTSRRLVPALSVLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVAEEKYREALEKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPQGELLEAIKRDFGSFAKFKEKLTAVSVGVQGSGWGWLGFNKEQGRLQIAACSNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTARYTACSK", "length": 492, "header": "tr|E1BHL1-1|E1BHL1_BOVIN Isoform 1 of Superoxide dismutase [Mn], mitochondrial OS=Bos taurus OX=9913 GN=SOD2 PE=3 SV=3 CANONICAL=E1BHL1-1" }, "locus": { "chromosome": "9", "start_pos": 95966127, "end_pos": 95956001, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008569.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008569.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008569.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008569.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 48, "start_aa": "Thr", "end_pos": 48, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr48", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 91, "start_aa": "Thr", "end_pos": 91, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr91", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-2151201", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2151201", "resource": "Reactome", "description": "Transcriptional activation of mitochondrial biogenesis" }, { "id": "R-BTA-3299685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3299685", "resource": "Reactome", "description": "Detoxification of Reactive Oxygen Species" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "E1BHL1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BHL1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BHL1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1" } ], "pmid": "" }, { "name": "superoxide dismutase activity", "id": "GO:0004784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004784", "evidence": [ { "database": "UniProtKB", "id": "E1BHL1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "E1BHL1", "url": "https://www.uniprot.org/uniprotkb/E1BHL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20696", "name": "", "equation": "2 superoxide + 2 H(+) = H2O2 + O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BHL1-1", "A0AAF6ZBG6-1", "P00442-1", "E1BMU2-1", "P41976-1", "F1MNQ4-1", "E1BE86-1" ], "evidence": [ { "id": "20696", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20696" } ] }, { "id": "R-BTA-3299680", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-3299683" ], "output_participant_list": [], "enzyme_list": [ "E1BHL1-1" ], "evidence": [ { "id": "R-BTA-3299680", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3299680" } ] }, { "id": "R-BTA-5688289", "name": "SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-5688337" ], "enzyme_list": [ "Q04467-1", "G5E521-1", "A0A140T871-1", "E1BHL1-1" ], "evidence": [ { "id": "R-BTA-5688289", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5688289" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-3299683", "participant_name": "O2.- [mitochondrial matrix]", "crossref": [ { "id": "18421", "database": "ChEBI", "url": "" }, { "id": "C00704", "database": "COMPOUND", "url": "" }, { "id": "HMDB0002168", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-5688337", "participant_name": "2'-O-acetyl-ADP-ribose [mitochondrial matrix]", "crossref": [ { "id": "83767", "database": "ChEBI", "url": "" }, { "id": "ZINC000096095472", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T871", "gene_name": "GLUD1", "activity": [ { "ec_number": "1.4.1.3", "activity": "L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+).", "evidence": [ { "id": "A0A140T871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ] }, { "ec_number": "1.4.1.3", "activity": "", "evidence": [ { "id": "A0A140T871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ] } ] }, { "uniprot_ac": "A0AAF6ZBG6", "gene_name": "SOD1", "activity": [ { "ec_number": "1.15.1.1", "activity": "2 superoxide + 2 H(+) = H2O2 + O2.", "evidence": [ { "id": "A0AAF6ZBG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZBG6" } ] }, { "ec_number": "1.15.1.1", "activity": "", "evidence": [ { "id": "A0AAF6ZBG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZBG6" } ] } ] }, { "uniprot_ac": "E1BE86", "gene_name": "CCS", "activity": [ { "ec_number": "1.15.1.1", "activity": "2 superoxide + 2 H(+) = H2O2 + O2.", "evidence": [ { "id": "E1BE86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE86" } ] }, { "ec_number": "1.15.1.1", "activity": "", "evidence": [ { "id": "E1BE86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE86" } ] } ] }, { "uniprot_ac": "E1BHL1", "gene_name": "SOD2", "activity": [ { "ec_number": "1.15.1.1", "activity": "2 superoxide + 2 H(+) = H2O2 + O2.", "evidence": [ { "id": "E1BHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL1" } ] }, { "ec_number": "1.15.1.1", "activity": "", "evidence": [ { "id": "E1BHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL1" } ] } ] }, { "uniprot_ac": "E1BMU2", "gene_name": "CYGB", "activity": [ { "ec_number": "1.15.1.1", "activity": "2 superoxide + 2 H(+) = H2O2 + O2.", "evidence": [ { "id": "E1BMU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMU2" } ] }, { "ec_number": "1.15.1.1", "activity": "", "evidence": [ { "id": "E1BMU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMU2" } ] } ] }, { "uniprot_ac": "F1MNQ4", "gene_name": "", "activity": [ { "ec_number": "1.15.1.1", "activity": "2 superoxide + 2 H(+) = H2O2 + O2.", "evidence": [ { "id": "F1MNQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNQ4" } ] }, { "ec_number": "1.15.1.1", "activity": "", "evidence": [ { "id": "F1MNQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNQ4" } ] } ] }, { "uniprot_ac": "G5E521", "gene_name": "SIRT3", "activity": [ { "ec_number": "2.3.1.286", "activity": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].", "evidence": [ { "id": "G5E521", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ] }, { "ec_number": "2.3.1.286", "activity": "", "evidence": [ { "id": "G5E521", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ] } ] }, { "uniprot_ac": "P00442", "gene_name": "SOD1", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P00442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00442" } ] }, { "ec_number": "1.15.1.1", "activity": "2 superoxide + 2 H(+) = H2O2 + O2.", "evidence": [ { "id": "P00442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00442" } ] }, { "ec_number": "1.15.1.1", "activity": "", "evidence": [ { "id": "P00442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00442" } ] } ] }, { "uniprot_ac": "P41976", "gene_name": "SOD2", "activity": [ { "ec_number": "1.15.1.1", "activity": "2 superoxide + 2 H(+) = H2O2 + O2.", "evidence": [ { "id": "P41976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41976" } ] }, { "ec_number": "1.15.1.1", "activity": "", "evidence": [ { "id": "P41976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41976" } ] } ] }, { "uniprot_ac": "Q04467", "gene_name": "IDH2", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "Q04467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04467" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "Q04467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04467" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHL1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 492, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHL1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHL1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL1" }, { "id": "PF02777", "database": "Pfam", "url": 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"id": "PIRSR000349-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000349-1" } ], "binding_site_uniprot": 123, "amino_acid": "Gln", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 123, "end_pos": 123, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0AAA9TNU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU0#function" }, { "id": "A0AAA9TNU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU0" }, { "id": "PIRSR000349-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000349-1" } ], "binding_site_uniprot": 127, "amino_acid": "Ser", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 127, "end_pos": 127, 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"url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000349-1" } ], "binding_site_uniprot": 148, "amino_acid": "Ala", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 148, "end_pos": 148, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0AAA9TNU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU0#function" }, { "id": "A0AAA9TNU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU0" }, { "id": "PIRSR000349-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000349-1" }, { "id": "A0AAA9U061", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U061#function" }, { "id": "A0AAA9U061", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U061" } ], "binding_site_uniprot": 50, "amino_acid": "Ser", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 50, "end_pos": 50, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0AAA9TNU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU0#function" }, { "id": "A0AAA9TNU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU0" }, { "id": "PIRSR000349-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000349-1" } ], "binding_site_uniprot": 98, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 98, "end_pos": 98, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.15.1.1", "ec_name": "2 superoxide + 2 H(+) = H2O2 + O2.", "evidence": [ { "id": "1.15.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.15.1.1" }, { "id": "1.15.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.15.1.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 48, 91 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 367, "end_pos": 369 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 482, "end_pos": 484 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGF8-1", "uniprot_ac": "E1BGF8", "uniprot_id": "E1BGF8_BOVIN", "mass": { "chemical_mass": 49255.0, "monoisotopic_mass": 49255.0 }, "refseq": { "ac": "NP_001179443", "name": "glycerol-3-phosphate acyltransferase 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179443" }, "gene_names": [ { "name": "GPAT3", "type": "recommended", "evidence": [ { "id": "E1BGF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGF8" } ] }, { "name": "AGPAT9", "type": "synonym", "evidence": [ { "id": "NP_001179443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179443" } ] }, { "name": "GPAT3", "type": "synonym", "evidence": [ { "id": "NP_001179443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179443" } ] } ], "protein_names": [ { "name": "1-acylglycerol-3-phosphate O-acyltransferase 9", "type": "synonym", "evidence": [ { "id": "NP_001179443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179443" } ] }, { "name": "Glycerol-3-phosphate acyltransferase 3", "type": "synonym", "evidence": [ { "id": "E1BGF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGF8/entry#names_and_taxonomy" } ] }, { "name": "glycerol-3-phosphate acyltransferase 3", "type": "synonym", "evidence": [ { "id": "NP_001179443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179443" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGF8", "url": "https://www.uniprot.org/uniprotkb/E1BGF8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPAT3", "url": "https://www.uniprot.org/uniprotkb/E1BGF8", "locus": { "chromosome": "6", "start_pos": 98360326, "end_pos": 98289255, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017592", "url": "https://www.ensembl.org/id/ENSBTAG00000017592" } ] } } ], "crossref": [ { "id": "E1BGF8", "url": "https://alphafold.ebi.ac.uk/entry/E1BGF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017592", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017592", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07991", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07991", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "519739", "url": "https://www.ncbi.nlm.nih.gov/gene/519739", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519739", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519739", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAGNGCR", "url": "https://omabrowser.org/oma/group/MAGNGCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGF8", "url": "https://www.orthodb.org/?gene=E1BGF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23063:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23063:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1483166", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179443", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179443", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SIY0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIY0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUF7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUF7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUV3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUV3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGF8", "url": "https://www.uniprot.org/uniprotkb/E1BGF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGF8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGAELAGQILYTWLTLVLGLILLPSAFGVSLGISEIYMKILVKTLEWATLRIETGVAKQSVLKNSASVGIIQRDESPMEKGLSGLRGRDFELSDVFYFSKKGLEAIVEDEVTQRFSSEELVSWNLLTRTNVNFQYVSPRLTMVWVLGVIVRYCVLLPLRLTLAVIGISLFVIGTTLVGQLPRNRLKNFLSEVVHLTCCRICVRALSGTIHYHNRQYRPQKGGICVANHTSPIDVLILTTDGCYTMVGQVHGGLMGIIQRSMVKACPHIWFERSEMKDRHLVIRRLKEHIALKEELPILIFPEGTCINNTSVMMFKKGSFEIGGTIHPVAIKYNPRFGDAFWNSSKYNIVSYLLRVMTSWAIVCDVWYMPPMTREEGEDAVQFANRVKSAIAVQGGLTELPWDGGLKRAKVKDTFKEEQQKNYSKMIVGNGSLKSELD", "length": 438, "header": "tr|E1BGF8-1|E1BGF8_BOVIN Isoform 1 of Glycerol-3-phosphate acyltransferase 3 OS=Bos taurus OX=9913 GN=GPAT3 PE=3 SV=1 CANONICAL=E1BGF8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SIY0-1", "url": "https://www.uniprot.org/uniprotkb/E1BGF8/entry#A0AAA9SIY0-1", "sequence": { "sequence": "MPGLLRSDRGGLSVSSPSGERKDACSLRIIQRDESPMEKGLSGLRGRDFELSDVFYFSKKGLEAIVEDEVTQRFSSEELVSWNLLTRTNVNFQYVSPRLTMVWVLGVIVRYCVLLPLRLTLAVIGISLFVIGTTLVGQLPRNRLKNFLSEVVHLTCCRICVRALSGTIHYHNRQYRPQKGGICVANHTSPIDVLILTTDGCYTMVGQVHGGLMGIIQRSMVKACPHIWFERSEMKDRHLVIRRLKEHIALKEELPILIFPEGTCINNTSVMMFKKGSFEIGGTIHPVAIKYNPRFGDAFWNSSKYNIVSYLLRVMTSWAIVCDVWYMPPMTREEGEDAVQFANRVKSAIAVQGGLTELPWDGGLKRAKVKDTFKEEQQKNYSKMIVGNGSLKSELD", "length": 396, "header": "tr|A0AAA9SIY0-1|E1BGF8_BOVIN Computationally mapped isoform of Glycerol-3-phosphate acyltransferase 3 OS=Bos taurus OX=9913 GN=GPAT3 PE=3 SV=1 CANONICAL=E1BGF8-1" }, "locus": { "chromosome": "6", "start_pos": 98359175, "end_pos": 98322404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116759.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116759.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082508.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082508.1" } ] } }, { "isoform_ac": "A0AAA9SUF7-1", "url": "https://www.uniprot.org/uniprotkb/E1BGF8/entry#A0AAA9SUF7-1", "sequence": { "sequence": "MLANYAWASKIRPGRPQCLLSFGRTEGRLQPTWILYQLSRQGSPPSHTCIIQRDESPMEKGLSGLRGRDFELSDVFYFSKKGLEAIVEDEVTQRFSSEELVSWNLLTRTNVNFQYVSPRLTMVWVLGVIVRYCVLLPLRLTLAVIGISLFVIGTTLVGQLPRNRLKNFLSEVVHLTCCRICVRALSGTIHYHNRQYRPQKGGICVANHTSPIDVLILTTDGCYTMVGQVHGGLMGIIQRSMVKACPHIWFERSEMKDRHLVIRRLKEHIALKEELPILIFPEGTCINNTSVMMFKKGSFEIGGTIHPVAIKYNPRFGDAFWNSSKYNIVSYLLRVMTSWAIVCDVWYMPPMTREEGEDAVQFANRVKSAIAVQGGLTELPWDGGLKRAKVKDTFKEEQQKNYSKMIVGNGSLKSELD", "length": 417, "header": "tr|A0AAA9SUF7-1|E1BGF8_BOVIN Computationally mapped isoform of Glycerol-3-phosphate acyltransferase 3 OS=Bos taurus OX=9913 GN=GPAT3 PE=3 SV=1 CANONICAL=E1BGF8-1" }, "locus": { "chromosome": "6", "start_pos": 98359175, "end_pos": 98322391, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099964.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099964.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090082.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090082.1" } ] } }, { "isoform_ac": "A0AAA9TUV3-1", "url": "https://www.uniprot.org/uniprotkb/E1BGF8/entry#A0AAA9TUV3-1", "sequence": { "sequence": "MDGAELAGQILYTWLTLVLGLILLPSAFGVSLGISEIYMKILVKTLEWATLRIETGVAKQSVLKNSASVGIIQRDESPMEKGLSGLRGRDFELSDVFYFSKKGLEAIVEDEVTQRFSSEELVSWNLLTRTNVNFQYVSPRLTMVWVLGVIVRYCVLLPLRLKNFLSEVVHLTCCRICVRALSGTIHYHNRQYRPQKGGICVANHTSPIDVLILTTDGCYTMVGQVHGGLMGIIQRSMVKACPHIWFERSEMKDRHLVIRRLKEHIALKEELPILIFPEGTCINNTSVMMFKKGSFEIGGTIHPVAIKYNPRFGDAFWNSSKYNIVSYLLRVMTSWAIVCDVWYMPPMTREEGEDAVQFANRVKSAIAVQGGLTELPWDGGLKRAKVKDTFKEEQQKNYSKMIVGNGSLKSELD", "length": 413, "header": "tr|A0AAA9TUV3-1|E1BGF8_BOVIN Computationally mapped isoform of Glycerol-3-phosphate acyltransferase 3 OS=Bos taurus OX=9913 GN=GPAT3 PE=3 SV=1 CANONICAL=E1BGF8-1" }, "locus": { "chromosome": "6", "start_pos": 98359175, "end_pos": 98289617, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113883.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113883.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100911.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100911.1" } ] } }, { "isoform_ac": "E1BGF8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGF8/entry#E1BGF8-1", "sequence": { "sequence": "MDGAELAGQILYTWLTLVLGLILLPSAFGVSLGISEIYMKILVKTLEWATLRIETGVAKQSVLKNSASVGIIQRDESPMEKGLSGLRGRDFELSDVFYFSKKGLEAIVEDEVTQRFSSEELVSWNLLTRTNVNFQYVSPRLTMVWVLGVIVRYCVLLPLRLTLAVIGISLFVIGTTLVGQLPRNRLKNFLSEVVHLTCCRICVRALSGTIHYHNRQYRPQKGGICVANHTSPIDVLILTTDGCYTMVGQVHGGLMGIIQRSMVKACPHIWFERSEMKDRHLVIRRLKEHIALKEELPILIFPEGTCINNTSVMMFKKGSFEIGGTIHPVAIKYNPRFGDAFWNSSKYNIVSYLLRVMTSWAIVCDVWYMPPMTREEGEDAVQFANRVKSAIAVQGGLTELPWDGGLKRAKVKDTFKEEQQKNYSKMIVGNGSLKSELD", "length": 438, "header": "tr|E1BGF8-1|E1BGF8_BOVIN Isoform 1 of Glycerol-3-phosphate acyltransferase 3 OS=Bos taurus OX=9913 GN=GPAT3 PE=3 SV=1 CANONICAL=E1BGF8-1" }, "locus": { "chromosome": "6", "start_pos": 98359175, "end_pos": 98289617, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023396.8", "url": "https://www.ensembl.org/id/ENSBTAT00000023396.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023396.5", "url": "https://www.ensembl.org/id/ENSBTAP00000023396.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:519739", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519739", "resource": "KEGG Pathway" }, { "id": "R-BTA-1483166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483166", "resource": "Reactome", "description": "Synthesis of PA" } ], "orthologs": [ { "uniprot_canonical_ac": "G3IK30-1", "protein_name": "Glycerol-3-phosphate acyltransferase 3 isoform X1", "gene_name": "Gpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGADLAVKVLSTWLTLVVGLIVLPSAFGLSLGISEFYMKILVKTLEWATLRIEKGAPNESVLKNSASVGIIQRDESPMEKGLSGLRGRVFELSDVFYFSKKGLEAIVEDEVTQRFSSEELVSWNLLTRTNVNFQYISPKLTMVWVLGVLIRYCFLLPLRVTLAFIGISLLIIGTTLVGQLPDSRIKNWLSELVHLTCCRICVRSLSGTIHYHNKQYRPQKGGICVANHTSPIDVLILTTDGCYAMVGQVHGGLMGIIQRAMVKACPHVWFERSEMKDRHLVTKRLREHVADKKKLPILIFPEGTCINNTSVMMFKKGSFEIGGTIYPVAIKYNPQFGDAFWNSSKYGMVSYLLRIMTSWAIVCDVWYMPPMTREEGEDAVQFANRVKSAIAVQGGLTELPWDGGLKRAKVKDTFKEEQQKNYSKMIVGNGSPNLELD", "length": 438 }, "evidence": [ { "id": "E1BGF8", "url": "https://omabrowser.org/oma/group/E1BGF8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6DG38-1", "protein_name": "Glycerol-3-phosphate acyltransferase 3", "gene_name": "gpat3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEGAWDVAFVLLHVWMSIVAGLIVLPAMFGVSLGFTDIYIKLLVKTLEWATLRIQRGQKEQPTLPLQLANGIIEKDDGSMEEEIVELRRSHPKNLAEGNFTLCDAFYFCKKGIENIVEDQVTQRFSSEELASWNLLTRTNNNFRYISVRLTIIWGLGVFVRYCVLLPLRITLAVIGLSWLVIGTTLVGFLPNSKVKNWLSDLVHITCYRICARGLSATIRYHNKENRPKKGGICVANHTSPIDIVILANDGCYAMVGQVHGGLMGVIQRSMVRSCPHVWFERSEMKDRHAVAKRLKDHISDKTKLPILIFPEGTCINNTSVMMFKKGSFEFGGTIYPVAIKYDPRFGDAFWNSAKYNMVSYILRMMTSWAIVCNVWYLPPMTQQDGEDAVHFANRVKSAIAHQGGLVDLSWDGGLKRSKVKESFKEEQQKMYSSMIVGLDSHEATVGPA", "length": 449 }, "evidence": [ { "id": "E1BGF8", "url": "https://omabrowser.org/oma/group/E1BGF8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BGF8", "url": "https://www.uniprot.org/uniprotkb/E1BGF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "E1BGF8", "url": "https://www.uniprot.org/uniprotkb/E1BGF8" } ], "pmid": "" }, { "name": "triglyceride biosynthetic process", "id": "GO:0019432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019432", "evidence": [ { "database": "UniProtKB", "id": "E1BGF8", "url": "https://www.uniprot.org/uniprotkb/E1BGF8" } ], "pmid": "" }, { "name": "regulation of TOR signaling", "id": "GO:0032006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032006", "evidence": [ { "database": "UniProtKB", "id": "E1BGF8", "url": "https://www.uniprot.org/uniprotkb/E1BGF8" } ], "pmid": "" }, { "name": "glycerol-3-phosphate metabolic process", "id": "GO:0006072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006072", "evidence": [ { "database": "UniProtKB", "id": "E1BGF8", "url": "https://www.uniprot.org/uniprotkb/E1BGF8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "O-acyltransferase activity", "id": "GO:0008374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008374", "evidence": [ { "database": "UniProtKB", "id": "E1BGF8", "url": "https://www.uniprot.org/uniprotkb/E1BGF8" } ], "pmid": "" }, { "name": "1-acylglycerol-3-phosphate O-acyltransferase activity", "id": "GO:0003841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003841", "evidence": [ { "database": "UniProtKB", "id": "E1BGF8", "url": "https://www.uniprot.org/uniprotkb/E1BGF8" } ], "pmid": "" }, { "name": "glycerol-3-phosphate O-acyltransferase activity", "id": "GO:0004366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004366", "evidence": [ { "database": "UniProtKB", "id": "E1BGF8", "url": "https://www.uniprot.org/uniprotkb/E1BGF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGF8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 438, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGF8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGF8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGF8" }, { "id": "SM00563", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00563" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phospholipid/glycerol acyltransferase", "eco_id": "ECO_0000259", "start_pos": 223, "end_pos": 334, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 309, "end_pos": 311 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 430, "end_pos": 432 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJ07-1", "uniprot_ac": "E1BJ07", "uniprot_id": "E1BJ07_BOVIN", "mass": { "chemical_mass": 71006.0, "monoisotopic_mass": 71006.0 }, "refseq": { "ac": "XP_010818510", "name": "XK-related protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818510" }, "gene_names": [ { "name": "XKR5", "type": "recommended", "evidence": [ { "id": "E1BJ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ07" } ] }, { "name": "XKR5", "type": "synonym", "evidence": [ { "id": "XP_010818510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818510" } ] } ], "protein_names": [ { "name": "XK-related protein", "type": "recommended", "evidence": [ { "id": "E1BJ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ07/entry#names_and_taxonomy" } ] }, { "name": "XK-related protein 5", "type": "synonym", "evidence": [ { "id": "XP_010818510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818510" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJ07", "url": "https://www.uniprot.org/uniprotkb/E1BJ07" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "XKR5", "url": "https://www.uniprot.org/uniprotkb/E1BJ07", "locus": { "chromosome": "27", "start_pos": 5895148, "end_pos": 5913373, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007473", "url": "https://www.ensembl.org/id/ENSBTAG00000007473" } ] } } ], "crossref": [ { "id": "E1BJ07", "url": "https://alphafold.ebi.ac.uk/entry/E1BJ07", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007473", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007473", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "529365", "url": "https://www.ncbi.nlm.nih.gov/gene/529365", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:529365", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529365", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VDSTCHW", "url": "https://omabrowser.org/oma/group/VDSTCHW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJ07", "url": "https://www.orthodb.org/?gene=E1BJ07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010818510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818510", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SL52", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SL52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SL52-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SL52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ07", "url": "https://www.uniprot.org/uniprotkb/E1BJ07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ07-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHAGVLGLSALLLAAEQSARLCAVIYYFTTGRLLWAWLVLLVLLPGFLVQGLSYLWFREDGRQGGCLLVVLHLLQLGVWKRHWDAVSASLWKEGQAAPQTRLLLWEADLAALHLLEALLQVGPHLLVQTYVFLASDFTAPVPGVSALCSWTTLSWALVCYARSLRSMKPDHSSAPWTALGCQQLWRMGMVGARVLSLVLFFWAYRVWVLVVAGAHWLVMTFWLVAQQSDIVDSTCRWRLFNLLMGAVFILCYLNVWDGPSRNRMVTFYTVMLLENIILVLLATDFLQGASWTSLGAVAGVLSGFLIGSVSLVLYYSLLHPKSTDIWRGCVHTSCGPTEGNKAEEDSSPQAPGPAGEGLDSLGPCPEETSELPSLEKPPSPQWTPPEAGLESQTAGEASLLSRHHWLLVKLALKTGNVSKINAAFGEDGLARFCSPEWGLSQHHSEGRTPPPPQQEPPSSPQDPLTSEEGSEFPVVPKAEAEETSSYLSFDSQSPDRAPAQQPSAARWEGGSEEGSRAAPGARGAGGHPGGEGGQGGSTLYFSATAEGALPSPAEPTPLSGRGLGLGSSAQPATERFPLSVADISPILGPGGRLQPSGRARGGAGLRGQRESPRRPVAAGTQRPLPEVHPRPVDAPCLTSTPVHGARRGLRPQGEADGRGFLH", "length": 662, "header": "tr|E1BJ07-1|E1BJ07_BOVIN Isoform 1 of XK-related protein OS=Bos taurus OX=9913 GN=XKR5 PE=3 SV=2 CANONICAL=E1BJ07-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SL52-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ07/entry#A0AAA9SL52-1", "sequence": { "sequence": "MGLQLRDPQGLCAVIYYFTTGRLLWAWLVLLVLLPGFLVQGLSYLWFREDGRQGGCLLVVLHLLQLGVWKRHWDAVSASLWKEGQAAPQTRLLLWEADLAALHLLEALLQVGPHLLVQTYVFLASDFTAPVPGVSALCSWTTLSWALVCYARSLRSMKPDHSSAPWTALGCQQLWRMGMVGARVLSLVLFFWAYRVWVLVVAGAHWLVMTFWLVAQQSDIVDSTCRWRLFNLLMGAVFILCYLNVWDGPSRNRMVTFYTVMLLENIILVLLATDFLQGASWTSLGAVAGVLSGFLIGSVSLVLYYSLLHPKSTDIWRGCVHTSCGPTEGNKAEEDSSPQAPGPAGEGLDSLGPCPEETSELPSLEKPPSPQWTPPEAGLESQTAGEASLLSRHHWLLVKLALKTGNVSKINAAFGEDGLARFCSPEWGLSQHHSEGRTPPPPQQEPPSSPQDPLTSEEGSEFPVVPKAEAEETSSYLSFDSQSPDRAPAQQPSAARWEGGSEEGSRAAPGARGAGGHPGGEGGQGGSTLYFSATAEGALPSPAEPTPLSGRGLGLGSSAQPATERFPLSVADISPILGPGGRLQPSGRARGGAGLRGQRESPRRPVAAGTQRPLPEVHPRPVDAPCLTSTPVHGARRGLRPQGEADGRGFLH", "length": 652, "header": "tr|A0AAA9SL52-1|E1BJ07_BOVIN Computationally mapped isoform of XK-related protein OS=Bos taurus OX=9913 GN=XKR5 PE=3 SV=1 CANONICAL=E1BJ07-1" }, "locus": { "chromosome": "27", "start_pos": 5912490, "end_pos": 5896152, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112184.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112184.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084621.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084621.1" } ] } }, { "isoform_ac": "E1BJ07-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ07/entry#E1BJ07-1", "sequence": { "sequence": "MHAGVLGLSALLLAAEQSARLCAVIYYFTTGRLLWAWLVLLVLLPGFLVQGLSYLWFREDGRQGGCLLVVLHLLQLGVWKRHWDAVSASLWKEGQAAPQTRLLLWEADLAALHLLEALLQVGPHLLVQTYVFLASDFTAPVPGVSALCSWTTLSWALVCYARSLRSMKPDHSSAPWTALGCQQLWRMGMVGARVLSLVLFFWAYRVWVLVVAGAHWLVMTFWLVAQQSDIVDSTCRWRLFNLLMGAVFILCYLNVWDGPSRNRMVTFYTVMLLENIILVLLATDFLQGASWTSLGAVAGVLSGFLIGSVSLVLYYSLLHPKSTDIWRGCVHTSCGPTEGNKAEEDSSPQAPGPAGEGLDSLGPCPEETSELPSLEKPPSPQWTPPEAGLESQTAGEASLLSRHHWLLVKLALKTGNVSKINAAFGEDGLARFCSPEWGLSQHHSEGRTPPPPQQEPPSSPQDPLTSEEGSEFPVVPKAEAEETSSYLSFDSQSPDRAPAQQPSAARWEGGSEEGSRAAPGARGAGGHPGGEGGQGGSTLYFSATAEGALPSPAEPTPLSGRGLGLGSSAQPATERFPLSVADISPILGPGGRLQPSGRARGGAGLRGQRESPRRPVAAGTQRPLPEVHPRPVDAPCLTSTPVHGARRGLRPQGEADGRGFLH", "length": 662, "header": "tr|E1BJ07-1|E1BJ07_BOVIN Isoform 1 of XK-related protein OS=Bos taurus OX=9913 GN=XKR5 PE=3 SV=2 CANONICAL=E1BJ07-1" }, "locus": { "chromosome": "27", "start_pos": 5913347, "end_pos": 5896152, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009827.5", "url": "https://www.ensembl.org/id/ENSBTAT00000009827.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009827.4", "url": "https://www.ensembl.org/id/ENSBTAP00000009827.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 337, "start_aa": "Thr", "end_pos": 337, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr337", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:529365", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529365", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BT87-1", "protein_name": "XK-related protein", "gene_name": "XKR5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHAGVLGLSTLLLAAEQSARLYTVVYYFTTGQLLWGWLVLSVLLPGFLVQGLSYLWFCEDGHQGHCLLVLHLLQLGVWKRHWDTATTGLRRAGVATCPGQLLLQEADLSALRLLEALLQVGPHLLLQTYVFLASDFTDVVPGVSALCSWSALSWALVCYACFMGSLKLGHLAAPWTALSCQQLWRMGMVGARVLSLALFFKAYHVWVLVVGGAHWLVMTFWLVAQQSDIVDSTCHWRLFNLLVGAVYILCYLNFWDSPSRTRMATFYTIMLLENMILVLLATDFLQGVSWTSMWTAAGVLTGFLIGSISLVIYYSLLHPKSADIWQGFVKKSSSIAGGDKVVGDPSPRAQGPAGRRPESLGMFPEESYEMTSLGKPPSPQWGLPEAEQESQMAREDSFFSHHHWLLLKLALKTGNVSKIQAVLGEGNPGSFGSPAWGLNQHCNQQGKPPFSQQEHPLSPQDTLTLEKGSEFHVVPKAEADPLETSSYNSFTSDNPDKAPAQKASATWQEGNPEGGARDASGVQRRGGGGTSEGSTLYFSATAEGATSSNEEGREGPLHKSHSGSTLGKGRPAQPPSPLPATKPFPVTMANISPILGPGPGRSFYPSGRALGGSQPAEQQGSMGDRGHPPTAGTRTSLPKVSLRPADEPCLTSTPKSESTRRDCSWRERLKTETSFFI", "length": 677 }, "evidence": [ { "id": "E1BJ07", "url": "https://omabrowser.org/oma/group/E1BJ07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2QPH2-1", "protein_name": "XK-related protein", "gene_name": "Xkr5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFAGLLGLSALLQAAEQSARLCTIVYYFATGHLLWAWLALSVLLPGFLVQALSYLWFQADGHRGPWWLVLLHLLQLGVWKRHWDSLAAALWKGREAPCWGQLYLQEVDLSALRLLEALLQTGPHLLLQVYVFLDSGFTDTVPGISALLSWSSLSWALVSYNQFLGVMKPGHRAMLWAALLCQQLWRMGMLGARVLSLVLFCRVYRVWVLVVGGAHWLVMTFWLVAQQSDIVESTCHWRLFNLLVGAVYILCYINFWDSPSRSRMASFYLVMLLENSILLLLATDFLQRAPWASLWTVAGVLSGFLIGSVSLVIYYSLLHPKSADIQQNFLRKCCGPIENDKAESEPSPRAMVPAGERPESANWCQEESYELTSLDKASSPMQNTTEVGQGDQRSWEYSFYSHHHWLLVKLALKTGSVSKINAALGVNSPGCSCPPVLGSNQHCNLQRKPLFSQQDIPSSPCDPLALEKGSAYAGAPKAEMESLETSSFVSFASEHEDNSTAQKPPAPQEEDSPKDGPKADLEAQEMDAVGPLKGEEGQASTTLYFSATMERTTPSYQKGSPVALRASHLGTLRESRPVQPDLPQAVTKPFPVTMANISPIPGRNFCPSTGLLGRAPESSECEEWRGPAKDVSIQRSLPMMSLREPCFTSTPKSESIQRDCSCRDRKNQEVSFFI", "length": 674 }, "evidence": [ { "id": "E1BJ07", "url": "https://omabrowser.org/oma/group/E1BJ07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F7F7I4-1", "protein_name": "XK-related protein", "gene_name": "Xkr5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALWKGKEAPSWGQLHLQEADLSALRLLEALLQTGPHLLLQVYVFLASDFTDVVPGISALLSWSSLSWALVSYNRFLGIMKPGHRTMLWAALLCQQLWRMGMLGARVLTLVLFCRVYRVWVLVVGGAHWLVMTFWLVAQQSDIVESTCHWRLFNLLVGAVFILCYINFWDSPSRSRMASFYLVMLLENSILLLLATDFLQGAPWTSLWTVVGVLSGFLIGCASLVVYYSLLHPKSSDIQENFMRKCCGPIENNKSDSEPPPRAMVPTGERPDSSSWCQEKSYELTSLDKAPSPGKSTAELRLEEQRSGEDSFFSHHHWLLLKLALKTGSISKINAALGGDSPGCSCPPRLGSSQHCDLQRKPLFSQQDLPSSPRDPLTLEKGPEYVGAPKAEMESLETSSYISFASDLEDNATTQKPPATQEDSPKAGTKADLAAQGKDTDGPLKGKEGQESTTLYFSATMDRTTCHQKGSPVALRTSHLGTLGESRPVQPALPQAVTKPFPVALANISPIPGRNFCPDAGLPGRAPESSEWEEWEDPAKNPSTQSSLPKVRLRAAEEPCVTSTPKSESIQRDYNCRDRVKQEVSFFI", "length": 588 }, "evidence": [ { "id": "E1BJ07", "url": "https://omabrowser.org/oma/group/E1BJ07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5GH66-1", "protein_name": "XK-related protein 5", "gene_name": "Xkr5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHAGLLGLSALLQAAEQSARLCSIVFYFATGRLLWGWLALSVLLPGFLVQALSFLWFRADGHQGQWWLAVLHLLQLGVWKRHWDSVATALWKGKEAPSWGQLHLQEADLSALRLLEALLQTGPHLLLQAYVFLASDFTDIVPGISALLSWSSLSWALVSYNRFLGIMKPGHHTMLWAALLCQQLWRMGMLGARVLSLVLFCRVYRVWVLVVGGAHWLVMTFWLVAQQSDIVESTCHWRLFNLLVGAVFILCYINFWDSPSRSRVASFYLVMLLENSILLLLATDFLQGVPGTSLWTVVGVLSGFLIGCASLVIYYSLLHPKSSDIQQSFMRKCCGPIEDNKPESEPPPRAVDPTGEMPDSSSWCQEESYELTSLDKAPSPEQNTAEVGLGEQRSGESSFFSHHHWLLLKLALKTGSVSRINAALGGDSPGCSCPPLLGSSQHCDLQRKPLFSHQDLPSSPCDPLTLEKGSEYVGAPKAEMESLETSSYLSFASELEDNATTQKPPATQEDSPKLAGSKADLAAQGKETEGPLQGKEGQESTTLYFSAAMDRTTSHQRGSPVVLRISHSETLVESRPGQPALPQAVTKPFPVTVANISPIPGRNFRPSAELPGRAPDSSECEEWKDAARDPSMQSSLPKMRLKAAEEPCFTSTPKSESIQRDYSCRDRVRQEMSFFI", "length": 676 }, "evidence": [ { "id": "E1BJ07", "url": "https://omabrowser.org/oma/group/E1BJ07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UX68-1", "protein_name": "XK-related protein 5", "gene_name": "XKR5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHARLLGLSALLQAAEQSARLYTVAYYFTTGRLLWGWLALAVLLPGFLVQALSYLWFRADGHPGHCSLMMLHLLQLGVWKRHWDAALTSLQKELEAPHRGWLQLQEADLSALRLLEALLQTGPHLLLQTYVFLASDFTDIVPGVSTLFSWSSLSWALVSYTRFMGFMKPGHLAMPWAALFCQQLWRMGMLGTRVLSLVLFYKAYHFWVFVVAGAHWLVMTFWLVAQQSDIIDSTCHWRLFNLLVGAVYILCYLSFWDSPSRNRMVTFYMVMLLENIILLLLATDFLQGASWTSLQTIAGVLSGFLIGSVSLVIYYSLLHPKSTDIWQGCLRKSCGIAGGDKTERRDSPRATDLAGKRTESSGSCQGASYEPTILGKPPTPEQVPPEAGLGTQVAVEDSFLSHHHWLWVKLALKTGNVSKINAAFGDNSPAYCPPAWGLSQQDYLQRKALSAQQELPSSSRDPSTLENSSAFEGVPKAEADPLETSSYVSFASDQQDEAPTQNPAATQGEGTPKEGADAVSGTQGKGTGGQQRGGEGQQSSTLYFSATAEVATSSQQEGSPATLQTAHSGRRLGKSSPAQPASPHPVGLAPFPDTMADISPILGTGPCRGFCPSAGFPGRTLSISELEEPLEPKRELSHHAAVGVWVSLPQLRTAHEPCLTSTPKSESIQTDCSCREQMKQEPSFFI", "length": 686 }, "evidence": [ { "id": "E1BJ07", "url": "https://omabrowser.org/oma/group/E1BJ07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BJ07", "url": "https://www.uniprot.org/uniprotkb/E1BJ07" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BJ07", "url": "https://www.uniprot.org/uniprotkb/E1BJ07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJ07-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 662, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJ07-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJ07" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 337 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 416, "end_pos": 418 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJF0-1", "uniprot_ac": "E1BJF0", "uniprot_id": "E1BJF0_BOVIN", "mass": { "chemical_mass": 59744.0, "monoisotopic_mass": 59744.0 }, "refseq": {}, "gene_names": [ { "name": "LOC504295", "type": "recommended", "evidence": [ { "id": "E1BJF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF0" } ] } ], "protein_names": [ { "name": "Butyrophilin-like protein 1", "type": "recommended", "evidence": [ { "id": "E1BJF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJF0", "url": "https://www.uniprot.org/uniprotkb/E1BJF0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC504295", "url": "https://www.uniprot.org/uniprotkb/E1BJF0", "locus": {} } ], "crossref": [ { "id": "E1BJF0", "url": "https://alphafold.ebi.ac.uk/entry/E1BJF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007618", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007618", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05713", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05713", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100:SF134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100:SF134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BJF0", "url": "https://www.uniprot.org/uniprotkb/E1BJF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJF0-1", "url": "https://www.uniprot.org/uniprotkb/E1BJF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASHHLLSILGMNVLCFQRAPCSALKMAGFPGLFPAGVLPALLLWVSMWGSPASGFSVMGPAQPIKVSLGADATLPCQLSSEQSAAHMQIRWYRTQLSPAVLVYQDGQEQDGEQMLEYRGRTELVEDSIGRGAVALLIQHVRASDDGQYWCHFNDGHISREAVVELHVIGLGSAPHVRMMGPEDHGIQVLCSSGGWFPKPRVQWSDTAGEKLLSLSEYQTQDGDGLFHVEASLVVTDSSLGNVTCSIQNPVSGQEKASAIFLPEPFFPRTSPWKIALAGTLPVLVLLLIGISYIGWKEHKAKNGEVEKKKKASHERDKVAREKEEAHSLKRKLEEDLEQRKALYNKDWKKALIYPDWRKEQFERVLVIENHENVHQNNSDFRKEPQAVLCKEQGGGNLLKLDQKGFTKGRHYWEVDIEDTDEWTLGIYEEPTEKSELLSDLQKMKFNVLEKKGCEYRALICSRQGIFHKESLPIEKCPLKIVIFLDYEDSDISFYNMTDETHIFSFTHTNFSGSVYPYFKLKSMEFSPSA", "length": 530, "header": "tr|E1BJF0-1|E1BJF0_BOVIN Isoform 1 of Butyrophilin-like protein 1 OS=Bos taurus OX=9913 GN=LOC504295 PE=3 SV=3 CANONICAL=E1BJF0-1" }, "isoforms": [ { "isoform_ac": "E1BJF0-1", "url": "https://www.uniprot.org/uniprotkb/E1BJF0/entry#E1BJF0-1", "sequence": { "sequence": "MASHHLLSILGMNVLCFQRAPCSALKMAGFPGLFPAGVLPALLLWVSMWGSPASGFSVMGPAQPIKVSLGADATLPCQLSSEQSAAHMQIRWYRTQLSPAVLVYQDGQEQDGEQMLEYRGRTELVEDSIGRGAVALLIQHVRASDDGQYWCHFNDGHISREAVVELHVIGLGSAPHVRMMGPEDHGIQVLCSSGGWFPKPRVQWSDTAGEKLLSLSEYQTQDGDGLFHVEASLVVTDSSLGNVTCSIQNPVSGQEKASAIFLPEPFFPRTSPWKIALAGTLPVLVLLLIGISYIGWKEHKAKNGEVEKKKKASHERDKVAREKEEAHSLKRKLEEDLEQRKALYNKDWKKALIYPDWRKEQFERVLVIENHENVHQNNSDFRKEPQAVLCKEQGGGNLLKLDQKGFTKGRHYWEVDIEDTDEWTLGIYEEPTEKSELLSDLQKMKFNVLEKKGCEYRALICSRQGIFHKESLPIEKCPLKIVIFLDYEDSDISFYNMTDETHIFSFTHTNFSGSVYPYFKLKSMEFSPSA", "length": 530, "header": "tr|E1BJF0-1|E1BJF0_BOVIN Isoform 1 of Butyrophilin-like protein 1 OS=Bos taurus OX=9913 GN=LOC504295 PE=3 SV=3 CANONICAL=E1BJF0-1" }, "locus": { "chromosome": "23", "start_pos": 25907060, "end_pos": 25900327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016055.8", "url": "https://www.ensembl.org/id/ENSBTAT00000016055.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016055.7", "url": "https://www.ensembl.org/id/ENSBTAP00000016055.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "extrathymic T cell selection", "id": "GO:0045062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045062", "evidence": [ { "database": "UniProtKB", "id": "E1BJF0", "url": "https://www.uniprot.org/uniprotkb/E1BJF0" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "E1BJF0", "url": "https://www.uniprot.org/uniprotkb/E1BJF0" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "E1BJF0", "url": 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"https://www.ncbi.nlm.nih.gov/protein/NP_001192923" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKQ1", "url": "https://www.uniprot.org/uniprotkb/E1BKQ1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HS3ST2", "url": "https://www.uniprot.org/uniprotkb/E1BKQ1", "locus": { "chromosome": "25", "start_pos": 20592087, "end_pos": 20473990, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017391", "url": "https://www.ensembl.org/id/ENSBTAG00000017391" } ] } } ], "crossref": [ { "id": "E1BKQ1", "url": "https://alphafold.ebi.ac.uk/entry/E1BKQ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017391", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017391", "database": "Bgee", "categories": 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"Protein Classification" ] }, { "id": "PTHR10605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022928", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192923", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SR33", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SR33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SR33-1", "url": 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"https://www.uniprot.org/uniprotkb/E1BKQ1/entry#A0AAA9SR33-1", "sequence": { "sequence": "MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSLLCCCDDLGQSRLLGAPRCLRGPGAGGQKLLQESRPCDPSGPTPGEPGAPSAPAAGAPSPRLSGSNHSGSPKLGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRTLGLVDVSWNAIRIGMYALHLESWLRYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRLITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFSVTWRLGQLSLCFMTATSDGTCTPRFFRPQLDPLIIM", "length": 401, "header": "tr|A0AAA9SR33-1|E1BKQ1_BOVIN Computationally mapped isoform of Sulfotransferase OS=Bos taurus OX=9913 GN=HS3ST2 PE=3 SV=1 CANONICAL=E1BKQ1-1" }, "locus": { "chromosome": "25", "start_pos": 20591870, "end_pos": 20474135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096254.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096254.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087804.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087804.1" } ] } }, { "isoform_ac": "E1BKQ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BKQ1/entry#E1BKQ1-1", "sequence": { "sequence": "MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSLLCCCDDLGQSRLLGAPRCLRGPGAGGQKLLQESRPCDPSGPTPGEPGAPSAPAAGAPSPRLSGSNHSGSPKLGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRTLGLVDVSWNAIRIGMYALHLESWLRYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRLITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE", "length": 367, "header": "tr|E1BKQ1-1|E1BKQ1_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=HS3ST2 PE=3 SV=1 CANONICAL=E1BKQ1-1" }, "locus": { "chromosome": "25", "start_pos": 20590245, "end_pos": 20474135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023123.6", "url": "https://www.ensembl.org/id/ENSBTAT00000023123.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023123.4", "url": "https://www.ensembl.org/id/ENSBTAP00000023123.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:532099", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532099", "resource": "KEGG Pathway" }, { "id": "R-BTA-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ATW7-1", "protein_name": "Sulfotransferase", "gene_name": "HS3ST2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSLLCCCDDLGQSRLLGAPRCLRGPGAGGQKLLQKSRPCDPPGPTPSEPSAASAPAAAAPASRLSGVNHSGSPKLGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRTLGLVDASWNAIRIGMYALHLESWLRYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRLITDKHFYFNKTKGFPCLKKTQSSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE", "length": 367 }, "evidence": [ { "id": "E1BKQ1", "url": "https://omabrowser.org/oma/group/E1BKQ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q673U1-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 2", "gene_name": "Hs3st2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSFLCCCDGLGQSRLLGAPRCLRGPSASGQKLLAKSRPCDPPGPTPSEPSAPSAPAAAAPAPRLSGSNHSGSPKPGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLETQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRSLGLVDVSWNAIRIGMYALHLESWLRYFPLAQIHFVSGERLITDPAGEMGRIQDFLGIKRFITDKHFYFNKTKGFPCLKKPESTLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE", "length": 367 }, "evidence": [ { "id": "E1BKQ1", "url": "https://omabrowser.org/oma/group/E1BKQ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80W66-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 2", "gene_name": "Hs3st2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSFLCCCDGLGQSRLLGAPRCLRGPSASGQKLLAKSRPCDPPGPTPSEPSAPSAPAAAAPAPRLSGSNHSGSPKPGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLETQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRSLGLVDVSWNAIRIGMYALHLESWLRYFPLAQIHFVSGERLITDPAGEMGRIQDFLGIKRFITDKHFYFNKTKGFPCLKKPESTLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE", "length": 367 }, "evidence": [ { "id": "E1BKQ1", "url": "https://omabrowser.org/oma/group/E1BKQ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y278-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 2", "gene_name": "HS3ST2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSFLCCCDDLGRSRLLGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSGSNHSGSPKLGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRTLGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE", "length": 367 }, "evidence": [ { "id": "E1BKQ1", "url": "https://omabrowser.org/oma/group/E1BKQ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "E1BKQ1", "url": "https://www.uniprot.org/uniprotkb/E1BKQ1" } ], "pmid": "" }, { "name": "[heparan sulfate]-glucosamine 3-sulfotransferase activity", "id": "GO:0008467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008467", "evidence": [ { "database": "UniProtKB", "id": "E1BKQ1", "url": "https://www.uniprot.org/uniprotkb/E1BKQ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BKQ1", "url": "https://www.uniprot.org/uniprotkb/E1BKQ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "E1BKQ1", "url": "https://www.uniprot.org/uniprotkb/E1BKQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-2076611", "name": "HS3ST2-6 sulfate GlcN at C3 in heparan sulfate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKQ1-1", "E1BNJ7-1", "E1BP03-1" ], "evidence": [ { "id": "R-BTA-2076611", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2076611" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BKQ1", "gene_name": "HS3ST2", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BKQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ1" } ] } ] }, { "uniprot_ac": "E1BNJ7", "gene_name": "HS3ST3A1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7" } ] } ] }, { "uniprot_ac": "E1BP03", "gene_name": "HS3ST3B1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BP03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP03" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ1" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 350, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 79 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 306, "end_pos": 308 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK37-1", "uniprot_ac": "E1BK37", "uniprot_id": "E1BK37_BOVIN", "mass": { "chemical_mass": 36554.0, "monoisotopic_mass": 36554.0 }, "refseq": { "ac": "XP_005223314", "name": "3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223314" }, "gene_names": [ { "name": "HMGCLL1", "type": "recommended", "evidence": [ { "id": "E1BK37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ] }, { "name": "HMGCLL1", "type": "synonym", "evidence": [ { "id": "XP_005223314", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223314" } ] } ], "protein_names": [ { "name": "hydroxymethylglutaryl-CoA lyase", "type": "recommended", "evidence": [ { "id": "E1BK37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK37/entry#names_and_taxonomy" } ] }, { "name": "3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005223314", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223314" } ] }, { "name": "4.1.3.4", "type": "synonym", "evidence": [ { "id": "E1BK37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK37/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK37", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HMGCLL1", "url": "https://www.uniprot.org/uniprotkb/E1BK37", "locus": { "chromosome": "23", "start_pos": 4987742, "end_pos": 4789437, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025718", "url": "https://www.ensembl.org/id/ENSBTAG00000025718" } ] } } ], "crossref": [ { "id": "E1BK37", "url": "https://alphafold.ebi.ac.uk/entry/E1BK37", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000025718", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000025718", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07938", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07938", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "535508", "url": "https://www.ncbi.nlm.nih.gov/gene/535508", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VATAWDC", "url": "https://omabrowser.org/oma/group/VATAWDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MQ25", "url": "https://www.orthodb.org/?gene=A0A3Q1MQ25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BK37", "url": "https://www.orthodb.org/?gene=E1BK37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42738:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42738:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00682", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00682", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-77111", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77111", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005223314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223314", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24404", "url": "https://www.rhea-db.org/rhea/24404", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MQ25", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQ25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQ25-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQ25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SR63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SR63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SR63-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SR63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVF1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVF1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK37", "url": "https://www.uniprot.org/uniprotkb/E1BK37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK37-1", "url": "https://www.uniprot.org/uniprotkb/E1BK37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNVPCAVKHCLSYQQLLREHLWIGDSVAGALEPAQESAQLSGFPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQMADHTEVMKGIHQYPGIRYPVLTPNLQGFHRAVAAGATEVSVFGAASESFSKKNINCSIEESMKKFEEVVKSARHMNIPARGYVSCALGCPYEGNITLQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKKMLESVMKEIPPRALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGVNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFNA", "length": 340, "header": "tr|E1BK37-1|E1BK37_BOVIN Isoform 1 of hydroxymethylglutaryl-CoA lyase OS=Bos taurus OX=9913 GN=HMGCLL1 PE=3 SV=2 CANONICAL=E1BK37-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MQ25-1", "url": "https://www.uniprot.org/uniprotkb/E1BK37/entry#A0A3Q1MQ25-1", "sequence": { "sequence": "MGNVPCAVKHCLSYQQLLREHLWIGDSVAGALEPAQESAQLSGFPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQVAAGATEVSVFGAASESFSKKNINCSIEESMKKFEEVVKSARHMNIPARGYVSCALGCPYEGNITLQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKKMLESVMKEIPPRALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGVNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFNA", "length": 308, "header": "tr|A0A3Q1MQ25-1|E1BK37_BOVIN Computationally mapped isoform of hydroxymethylglutaryl-CoA lyase OS=Bos taurus OX=9913 GN=HMGCLL1 PE=3 SV=1 CANONICAL=E1BK37-1" }, "locus": { "chromosome": "23", "start_pos": 4986738, "end_pos": 4789563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069672.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069672.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074065.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074065.1" } ] } }, { "isoform_ac": "A0AAA9SR63-1", "url": "https://www.uniprot.org/uniprotkb/E1BK37/entry#A0AAA9SR63-1", "sequence": { "sequence": "MGNVPCAVKHCLSYQQLLREHLWIGDSVAGALEPAQESAQLSGFPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQVSKRLYGMGCYEISLGDTIGVGTPGSMKKMLESVMKEIPPRALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGVNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFNA", "length": 237, "header": "tr|A0AAA9SR63-1|E1BK37_BOVIN Computationally mapped isoform of hydroxymethylglutaryl-CoA lyase OS=Bos taurus OX=9913 GN=HMGCLL1 PE=3 SV=1 CANONICAL=E1BK37-1" }, "locus": { "chromosome": "23", "start_pos": 4986738, "end_pos": 4789563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122069.2", "url": "https://www.ensembl.org/id/ENSBTAT00000122069.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088832.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088832.1" } ] } }, { "isoform_ac": "A0AAA9TVF1-1", "url": "https://www.uniprot.org/uniprotkb/E1BK37/entry#A0AAA9TVF1-1", "sequence": { "sequence": "MGNVPCAVKHCLSYQQLLREHLWIGDSVAGALEPAQESAQLSGFPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGVNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFNA", "length": 174, "header": "tr|A0AAA9TVF1-1|E1BK37_BOVIN Computationally mapped isoform of hydroxymethylglutaryl-CoA lyase OS=Bos taurus OX=9913 GN=HMGCLL1 PE=3 SV=1 CANONICAL=E1BK37-1" }, "locus": { "chromosome": "23", "start_pos": 4986738, "end_pos": 4789563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091302.2", "url": "https://www.ensembl.org/id/ENSBTAT00000091302.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102342.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102342.1" } ] } }, { "isoform_ac": "E1BK37-1", "url": "https://www.uniprot.org/uniprotkb/E1BK37/entry#E1BK37-1", "sequence": { "sequence": "MGNVPCAVKHCLSYQQLLREHLWIGDSVAGALEPAQESAQLSGFPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQMADHTEVMKGIHQYPGIRYPVLTPNLQGFHRAVAAGATEVSVFGAASESFSKKNINCSIEESMKKFEEVVKSARHMNIPARGYVSCALGCPYEGNITLQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKKMLESVMKEIPPRALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGVNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFNA", "length": 340, "header": "tr|E1BK37-1|E1BK37_BOVIN Isoform 1 of hydroxymethylglutaryl-CoA lyase OS=Bos taurus OX=9913 GN=HMGCLL1 PE=3 SV=2 CANONICAL=E1BK37-1" }, "locus": { "chromosome": "23", "start_pos": 4986738, "end_pos": 4789563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019954.8", "url": "https://www.ensembl.org/id/ENSBTAT00000019954.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019954.5", "url": "https://www.ensembl.org/id/ENSBTAP00000019954.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-77111", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77111", "resource": "Reactome", "description": "Synthesis of Ketone Bodies" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X2E0-1", "protein_name": "hydroxymethylglutaryl-CoA lyase", "gene_name": "HMGCLL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGTVPSALKHCLSYQHLLKEQLWIGEPTAPPHPGQESQASGLPEYVKIVEVGPRDGLQNEKVIVPTDTKIELINRLSKTGLPAIEVTSFVSSKWVPQMADHKEVMRGIERHPGVQYPVLTPNLKGFHSAIAAGATEVSVFGAASESFSKMNINCSIEESIEKFEEVAKSARNMNIPVRGYVSCALGCPYEGDITPAKVAEVSKRLYSMGCYEISLGDTIGVGTPGSMKRMLEAVMKEIPLSALAVHCHDTYGQALANILTAIQMGVAVVDSSVAGLGGCPYAKGATGNVATEDVIYMLNGLGINTGVNLYTVMEAGNFICTALNKKTNSKVAQASFNTGAVK", "length": 342 }, "evidence": [ { "id": "E1BK37", "url": "https://omabrowser.org/oma/group/E1BK37/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A5C3-1", "protein_name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "gene_name": "Hmgcll1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNLPSAAKHCLNYQQLLREHLWSGESVAGALDPAQEASQLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWVPQMADHAEVMGGIHQYPGVRYPVLVPNLQGLQHAVAAGATEIAVFGAASESFSKKNINCSIEESMGRFEQVISSARHMNIPVRGYVSCALGCPYEGSIMPQKVTEVSKRLYSMGCYEISLGDTVGVGTPGSMKTMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGMGLNTGVDLHKVMEAGDFICKAVNKTTNSKVAQASFKARLE", "length": 343 }, "evidence": [ { "id": "E1BK37", "url": "https://omabrowser.org/oma/group/E1BK37/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RZW6-1", "protein_name": "hydroxymethylglutaryl-CoA lyase", "gene_name": "HMGCLL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQEPSRLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQMADHTEVMKGIRQYPGIRYPVLTPNLQGFHRAVAAGATEVSVFGAASESFSKKNINCSIEESMEKFEEVVKSARHMNIPARGYVSCALGCPYEGNITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKKILESVMKEIPPRALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLVYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFHA", "length": 340 }, "evidence": [ { "id": "E1BK37", "url": "https://omabrowser.org/oma/group/E1BK37/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8JZS7-1", "protein_name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "gene_name": "Hmgcll1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNLPSAAKHCLNYQQLLREHLWSGDSVAGALDAAQEASQLPGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIELINQLSQTGLSVIEVTSFVSSRWVPQMADHAEVMRGIRQYPGVRYPVLTPNLQGFQHAVAAGATEIAVFGAASESFSKKNINCSIEESMGRFQEVISSARHMDIPVRGYVSCALGCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKMMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGMGLNTGVDLYKVMEAGEFICKAVNKTTNSKVAQASFNARLE", "length": 343 }, "evidence": [ { "id": "E1BK37", "url": "https://omabrowser.org/oma/group/E1BK37/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TB92-1", "protein_name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "gene_name": "HMGCLL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQTSLLTNLHCFQPDVSGFSVSLAGTVACIHWETSQLSGLPEFVKIVEVGPRDGLQNEKVIVPTDIKIEFINRLSQTGLSVIEVTSFVSSRWVPQMADHTEVMKGIHQYPGVRYPVLTPNLQGFHHAVAAGATEISVFGAASESFSKKNINCSIEESMGKFEEVVKSARHMNIPARGYVSCALGCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKRMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFNA", "length": 370 }, "evidence": [ { "id": "E1BK37", "url": "https://omabrowser.org/oma/group/E1BK37/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VM58-1", "protein_name": "hydroxymethylglutaryl-CoA lyase", "gene_name": "Hmgcl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MISAPIRSILALTAKRTAVTSAANQVRIVEVGPRDGLQNEPKLLPAATKIELINQLSETGLRTIEATSFVSAKWVPQMGDNAEVLKGIRKVTGISYPVLTPNLKGFESALEAGAEEVAVFGAASDAFSLKNVNCTAAEAIERFKPVLKAAQKHGVRVRGYVSTVVGCPYEGAVAPSAVVKVVEALYQMGCYEISLGDTIGVGTPGTMRRMLDEVTKVVPAKDLAVHCHDTYGQALSNILVSLDYGIRVVDSSVSGLGGCPYAKGASGNAATEDVVYLLHGMGLDTGVNLDKLIQVGRYICTELGRTSESKVNRAWKGPQARVK", "length": 323 }, "evidence": [ { "id": "E1BK37", "url": "https://omabrowser.org/oma/group/E1BK37/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BK37", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ], "pmid": "" }, { "name": "hydroxymethylglutaryl-CoA lyase activity", "id": "GO:0004419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004419", "evidence": [ { "database": "UniProtKB", "id": "E1BK37", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BK37", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BK37", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BK37", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1BK37", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ketone body biosynthetic process", "id": "GO:0046951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046951", "evidence": [ { "database": "UniProtKB", "id": "E1BK37", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ], "pmid": "" }, { "name": "L-leucine catabolic process", "id": "GO:0006552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006552", "evidence": [ { "database": "UniProtKB", "id": "E1BK37", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24404", "name": "", "equation": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK37-1", "Q29448-1" ], "evidence": [ { "id": "24404", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24404" } ] }, { "id": "R-BTA-6788597", "name": "HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK37-1" ], "evidence": [ { "id": "R-BTA-6788597", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6788597" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BK37", "gene_name": "HMGCLL1", "activity": [ { "ec_number": "4.1.3.4", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "E1BK37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ] }, { "ec_number": "4.1.3.4", "activity": "", "evidence": [ { "id": "E1BK37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK37" } ] } ] }, { "uniprot_ac": "Q29448", "gene_name": "HMGCL", "activity": [ { "ec_number": "4.1.3.4", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "Q29448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29448" } ] }, { "ec_number": "4.1.3.4", "activity": "", "evidence": [ { "id": "Q29448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29448" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BK37-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 340, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BK37-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BK37" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BK37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK37" }, { "id": "PS50991", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50991" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pyruvate carboxyltransferase", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 315, "start_aa": "Val", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.1.3.4", "ec_name": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "4.1.3.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.4" }, { "id": "4.1.3.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.1.3.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 326, "end_pos": 328 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJU8-1", "uniprot_ac": "E1BJU8", "uniprot_id": "E1BJU8_BOVIN", "mass": { "chemical_mass": 60726.0, "monoisotopic_mass": 60726.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100296421", "type": "recommended", "evidence": [ { "id": "E1BJU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJU8" } ] } ], "protein_names": [ { "name": "UDP-glucuronosyltransferase", "type": "recommended", "evidence": [ { "id": "E1BJU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJU8/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.17", "type": "synonym", "evidence": [ { "id": "E1BJU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJU8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJU8", "url": "https://www.uniprot.org/uniprotkb/E1BJU8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC100296421", "url": "https://www.uniprot.org/uniprotkb/E1BJU8", "locus": {} } ], "crossref": [ { "id": "E1BJU8", "url": "https://alphafold.ebi.ac.uk/entry/E1BJU8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000049291", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049291", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000051713", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000051713", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03784", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03784", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WKFARTA", "url": "https://omabrowser.org/oma/group/WKFARTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJU8", "url": "https://www.orthodb.org/?gene=E1BJU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48043:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48043:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9753281", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9753281", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9757110", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9757110", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "21032", "url": "https://www.rhea-db.org/rhea/21032", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LWZ2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYL1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYL1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJU8", "url": "https://www.uniprot.org/uniprotkb/E1BJU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJU8-1", "url": "https://www.uniprot.org/uniprotkb/E1BJU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMKWLLLLQLLQLTCYFSSGNCGKVLVWPVEFSHWMNMKTILDELVMRGHEVTVLQSSASTLIDPNKPLAMKFETFPVSLTKDDFQTLAKILIETWCLRKDFFWIHLSTIQSLFDEFSDIGMKICSEVVSNKKLMTKLQESRFDVVLADAVGPCGELLAEILKVPLVYSLYFSPGYLVEKRSARLSFPPSYVPVMLSELSDHMTFMERVKNMIYVLYFDYWFQLYDEKKWNQFYSEVVGRPTTMAELMGKAEMWLIRNYWDFSFPRPRLPNVEFVGGLHCKPAKPLPKEMEEFVQSSGEHGIVVFSLGSMVSNISEERANVIASALAQIPQKVLWRYDGKKPDALGPNTWLFKWIPQNDLLGHPKTKAFITHGGSNGIYEAIYHGIPMVGLPLFADQPHNIVHMTAKGAAIRLDLETMSTEDLLNALKEVINNPFYKENIMRLSAIQHDQPMKPLDRAIFWIEFVMRHKGAKHLRPASHNLTWFQYHSLDVIGFLLACVTTVVFVITKCCLFCCRKFASIGKKRKRD", "length": 528, "header": "tr|E1BJU8-1|E1BJU8_BOVIN Isoform 1 of UDP-glucuronosyltransferase OS=Bos taurus OX=9913 GN=LOC100296421 PE=3 SV=5 CANONICAL=E1BJU8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LWZ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BJU8/entry#A0A3Q1LWZ2-1", "sequence": { "sequence": "MNKMSMKWLLLLQLLQLTCYFSSGNCGKVLVWPVEFSHWMNMKTILDELVMRGHEVTVLQSSASTLIDPNKPLAMKFETFPVSLTKDDFQTLAKILIETWMLAVKDFFWIHLSTIQSLFDEFSDIGMKICSEVVSNKKLMTKLQESRFDVVLADAVGPCGELLAEILKVPLVYSLYFSPGYLVEKRSARLSFPPSYVPVMLSELSDHMTFMERVKNMIYVLYFDYWFQLYDEKKWNQFYSEVVGRPTTMAELMGKAEMWLIRNYWDFSFPRPRLPNVEFVGGLHCKPAKPLPKEMEEFVQSSGEHGIVVFSLGSMVSNISEERANVIASALAQIPQKVLWRYDGKKPDALGPNTWLFKWIPQNDLLGHPKTKAFITHGGSNGIYEAIYHGIPMVGLPLFADQPHNIVHMTAKGAAIRLDLETMSTEDLLNALKEVINNPFYKENIMRLSAIQHDQLMKPLDRAVFWIEFVMCHKGVNHLRPAIHDLNWFQ", "length": 490, "header": "tr|A0A3Q1LWZ2-1|E1BJU8_BOVIN Computationally mapped isoform of UDP-glucuronosyltransferase OS=Bos taurus OX=9913 GN=LOC100296421 PE=3 SV=2 CANONICAL=E1BJU8-1" }, "locus": { "chromosome": "6", "start_pos": 84513082, "end_pos": 84473438, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076372.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076372.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061729.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061729.2" } ] } }, { "isoform_ac": "A0AAA9SYL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BJU8/entry#A0AAA9SYL1-1", "sequence": { "sequence": "MNKMSMKWLLLLQLLQLTCYFSSGNCGKVLVWPVEFSHWMNMKTILDELVMRGHEVTVLQSSASTLIDPNKPLAMKFETFPVSLTKDDFQTLAKILIETWMLAVKDFFWIHLSTIQSLFDEFSDIGMKICSEVVSNKKLMTKLQESRFDVVLADAVGPCGELLAEILKVPLVYSLYFSPGYLVEKRSARLSFPPSYVPVMLSELSDHMTFMERVKNMIYVLYFDYWFQLYDEKKWNQFYSEVVGRPTTMAELMGKAEMWLIRNYWDFSFPRPRLPNVEFVGGLHCKPAKPLPKVLWRYDGKKPDALGPNTWLFKWIPQNDLLGHPKTKAFITHGGSNGIYEAIYHGIPMVGLPLFADQPHNIVHMTAKGAAIRLDLETMSTEDLLNALKEVINNPFYKENIMRLSAIQHDQPMKPLDRAIFWIEFVMRHKGAKHLRPASHNLTWFQYHSLDVIGFLLACVTTVVFVITKCCLFCCRKFASIGKKRKRD", "length": 488, "header": "tr|A0AAA9SYL1-1|E1BJU8_BOVIN Computationally mapped isoform of UDP-glucuronosyltransferase OS=Bos taurus OX=9913 GN=LOC100296421 PE=3 SV=1 CANONICAL=E1BJU8-1" }, "locus": { "chromosome": "6", "start_pos": 84513082, "end_pos": 84497385, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107606.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107606.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088447.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088447.1" } ] } }, { "isoform_ac": "E1BJU8-1", "url": "https://www.uniprot.org/uniprotkb/E1BJU8/entry#E1BJU8-1", "sequence": { "sequence": "MSMKWLLLLQLLQLTCYFSSGNCGKVLVWPVEFSHWMNMKTILDELVMRGHEVTVLQSSASTLIDPNKPLAMKFETFPVSLTKDDFQTLAKILIETWCLRKDFFWIHLSTIQSLFDEFSDIGMKICSEVVSNKKLMTKLQESRFDVVLADAVGPCGELLAEILKVPLVYSLYFSPGYLVEKRSARLSFPPSYVPVMLSELSDHMTFMERVKNMIYVLYFDYWFQLYDEKKWNQFYSEVVGRPTTMAELMGKAEMWLIRNYWDFSFPRPRLPNVEFVGGLHCKPAKPLPKEMEEFVQSSGEHGIVVFSLGSMVSNISEERANVIASALAQIPQKVLWRYDGKKPDALGPNTWLFKWIPQNDLLGHPKTKAFITHGGSNGIYEAIYHGIPMVGLPLFADQPHNIVHMTAKGAAIRLDLETMSTEDLLNALKEVINNPFYKENIMRLSAIQHDQPMKPLDRAIFWIEFVMRHKGAKHLRPASHNLTWFQYHSLDVIGFLLACVTTVVFVITKCCLFCCRKFASIGKKRKRD", "length": 528, "header": "tr|E1BJU8-1|E1BJU8_BOVIN Isoform 1 of UDP-glucuronosyltransferase OS=Bos taurus OX=9913 GN=LOC100296421 PE=3 SV=5 CANONICAL=E1BJU8-1" }, "locus": { "chromosome": "6", "start_pos": 84513073, "end_pos": 84497385, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004581.8", "url": "https://www.ensembl.org/id/ENSBTAT00000004581.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004581.8", "url": "https://www.ensembl.org/id/ENSBTAP00000004581.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-9753281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9753281", "resource": "Reactome", "description": "Paracetamol ADME" }, { "id": "R-BTA-9757110", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9757110", "resource": "Reactome", "description": "Prednisone ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M3E3-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "AC114845.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPWKWISALLLLQISCCFKSGNCGKVLMWPMDFSHWMNIKIILDELVQRGHEVTVLKSSAFFFLDPKKSSDLKFELFPTSVSKDELQNHFIKLLDVWTYELPRDTYLSYSPILQNMVYEFSSFYLRLCKDAVSNKQLMAKLQSKFDLLLSDPVAACGDLIAELLHIPFLYSLRFSPGHKLEKSIGKCILPPSYVPVILSGLAGKMTFIDRVKNMICMLYFDFWFERLRHKEWDMFYSEILGRPTTVEETMGKAEMWLIRSYWDLEFPHPTLPNVDYVGGFHCKPAKSLPKDMEEFVQSSGEHGVVVFSLGSMVSNMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGPNTRVYTWLPQNDLLGHPKTKAFVTHGGANGLYEAIYHGIPMIGIPIFGEQYDNIAHMVAKGAAVSLNIRTMSKSDLLSALEEVIDNPFYKKNAMLLSTIHHDQPMKPLDRVVFWIEFIMCHKGAKHLRPLGHDLSWYQYHSLDVIGFLLACLAVIAALIVKCFLLVYQIFVKKEKTMKNE", "length": 529 }, "evidence": [ { "id": "E1BJU8", "url": "https://omabrowser.org/oma/group/E1BJU8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P06133-1", "protein_name": "UDP-glucuronosyltransferase 2B4", "gene_name": "UGT2B4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSMKWTSALLLIQLSCYFSSGSCGKVLVWPTEFSHWMNIKTILDELVQRGHEVTVLASSASISFDPNSPSTLKFEVYPVSLTKTEFEDIIKQLVKRWAELPKDTFWSYFSQVQEIMWTFNDILRKFCKDIVSNKKLMKKLQESRFDVVLADAVFPFGELLAELLKIPFVYSLRFSPGYAIEKHSGGLLFPPSYVPVVMSELSDQMTFIERVKNMIYVLYFEFWFQIFDMKKWDQFYSEVLGRPTTLSETMAKADIWLIRNYWDFQFPHPLLPNVEFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSMVSNTSEERANVIASALAKIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAVSLDFHTMSSTDLLNALKTVINDPLYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVTGFLLACVATVIFIITKCLFCVWKFVRTGKKGKRD", "length": 528 }, "evidence": [ { "id": "E1BJU8", "url": "https://omabrowser.org/oma/group/E1BJU8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BJU8", "url": "https://www.uniprot.org/uniprotkb/E1BJU8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "E1BJU8", "url": "https://www.uniprot.org/uniprotkb/E1BJU8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21032", "name": "", "equation": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9T3U6-1", "G3N150-1", "F1MFF6-1", "F1MRL5-1", "E1BBB3-1", "E1BJU8-1", "A0AAA9S6P8-1", "A0A3Q1M7T0-1", "A0A3Q1MKS1-1", "A0A3Q1LYU5-1", "A0AAA9TS57-1" ], "evidence": [ { "id": "21032", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21032" } ] }, { "id": "R-BTA-158546", "name": "UGTs glucuronate APAP to APAP-GlcA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-158601" ], "output_participant_list": [ "R-ALL-158604" ], "enzyme_list": [ "E1BJU8-1", "A0A3Q1LYU5-1", "F1MFF6-1", "E1BBB3-1" ], "evidence": [ { "id": "R-BTA-158546", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-158546" } ] }, { "id": "R-BTA-9758661", "name": "UGT2B7,2B17,1A3 glucuronidates PRED metabolites", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BJU8-1", "A0A3Q1LYU5-1", "F1MFF6-1", "E1BBB3-1" ], "evidence": [ { "id": "R-BTA-9758661", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9758661" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-158601", "participant_name": "UDP-GlcA [cytosol]", "crossref": [ { "id": "58052", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215691", "database": "ZINC", "url": "" }, { "id": "C00167", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-158604", "participant_name": "APAP-GlcA [endoplasmic reticulum lumen]", "crossref": [ { "id": "ZINC000005197198", "database": "ZINC", "url": "" }, { "id": "132962", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LYU5", "gene_name": "LOC100138908", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0A3Q1LYU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYU5" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0A3Q1LYU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYU5" } ] } ] }, { "uniprot_ac": "A0A3Q1M7T0", "gene_name": "LOC100140261", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0A3Q1M7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7T0" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0A3Q1M7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7T0" } ] } ] }, { "uniprot_ac": "A0A3Q1MKS1", "gene_name": "LOC530553", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0A3Q1MKS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKS1" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKS1" } ] } ] }, { "uniprot_ac": "A0AAA9S6P8", "gene_name": "LOC525484", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0AAA9S6P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6P8" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0AAA9S6P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6P8" } ] } ] }, { "uniprot_ac": "A0AAA9T3U6", "gene_name": "UGT1A1", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0AAA9T3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3U6" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0AAA9T3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3U6" } ] } ] }, { "uniprot_ac": "A0AAA9TS57", "gene_name": "LOC615303", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0AAA9TS57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS57" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0AAA9TS57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS57" } ] } ] }, { "uniprot_ac": "E1BBB3", "gene_name": "LOC100138004", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "E1BBB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBB3" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "E1BBB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBB3" } ] } ] }, { "uniprot_ac": "E1BJU8", "gene_name": "LOC100296421", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "E1BJU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJU8" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "E1BJU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJU8" } ] } ] }, { "uniprot_ac": "F1MFF6", "gene_name": "UGT2B10", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "F1MFF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFF6" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "F1MFF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFF6" } ] } ] }, { "uniprot_ac": "F1MRL5", "gene_name": "LOC540544", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "F1MRL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRL5" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "F1MRL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRL5" } ] } ] }, { "uniprot_ac": "G3N150", "gene_name": "UGT2A1", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "G3N150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N150" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "G3N150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N150" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJU8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 528, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJU8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJU8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.17", "ec_name": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "2.4.1.17", "database": "Rhea", "url": 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR002961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043226", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043226", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11471", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11471", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11471:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11471:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47904", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47904", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47904:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47904:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5668541", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5668541", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5676594", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5676594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LWP4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZ45", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZ45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZ45-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZ45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T488", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T488", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T488-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T488-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8Z1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLX3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLX3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVB7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVB7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK50", "url": "https://www.uniprot.org/uniprotkb/E1BK50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK50-1", "url": "https://www.uniprot.org/uniprotkb/E1BK50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QYZ6", "url": "https://www.uniprot.org/uniprotkb/F6QYZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QYZ6-1", "url": "https://www.uniprot.org/uniprotkb/F6QYZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VATINPPRASYCPCSLTSGYAPRLILLSWLGCPRDGDVLSVSLLVLFSCSCDAVVSRCHQAPSWSYVTGTADPGTQAPAHQRFESGELPEEDSETDLSPRLPAAHLIGAWTTGQGLGWEAKKEEAFLSSGTQFSGAEGLALPQDGLYYLYCHIGYRGRAPPPAVEPLDGSVTLLSRLYRAGGAYGSGTPELLLEGAETVTPVSDPARRHDYGPLWYTSVGFGGLVQLRRGERVYVNISHPDMVDYRRGKTFFGAVMVG", "length": 258, "header": "tr|E1BK50-1|E1BK50_BOVIN Isoform 1 of Lymphotoxin-beta OS=Bos taurus OX=9913 GN=LTB PE=3 SV=3 CANONICAL=E1BK50-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LWP4-1", "url": "https://www.uniprot.org/uniprotkb/E1BK50/entry#A0A3Q1LWP4-1", "sequence": { "sequence": "MTQRRLDTAMEGCVRCLRSQGVKVLGTPSDMAQMLLFIFIIIRPGSCVLWVSQPPEIRTQEGSPAFLPCSFNASQGSLAIGSVTWYRDKVAPGMEVRNETAEFQGRLAPLPSSRFLCDHQAELHIWDTRGRDTGVYVCRVEVLGLGVGTGNGTLLVVEEGPPQLAAGTVLLLRAGFYAFSFLSVAMGSSMYYQGKYHCHKGTPCHSLDGL", "length": 210, "header": "tr|A0A3Q1LWP4-1|E1BK50_BOVIN Computationally mapped isoform of Lymphotoxin-beta OS=Bos taurus OX=9913 GN=LTB PE=3 SV=2 CANONICAL=E1BK50-1" }, "locus": { "chromosome": "23", "start_pos": 27706002, "end_pos": 27698308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071628.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071628.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061662.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061662.2" } ] } }, { "isoform_ac": "A0AAA9SZ45-1", "url": "https://www.uniprot.org/uniprotkb/E1BK50/entry#A0AAA9SZ45-1", "sequence": { "sequence": "MQISPSAASSFLREGCVRCLRSQGVKVLGTPSDMAQMLLFIFIIIRPGSCVLWVSQPPEIRTQEGSPAFLPCSFNASQGSLAIGSVTWYRDKVAPGMEVRNETAEFQGRLAPLPSSRFLCDHQAELHIWDTRGRDTGVYVCRVEVLGLGVGTGNGTLLVVEEGPPQLAAGTVLLLRAGFYAFSFLSVAMGSSMYYQGKCECWSRDTWAWRWEGM", "length": 214, "header": "tr|A0AAA9SZ45-1|E1BK50_BOVIN Computationally mapped isoform of Lymphotoxin-beta OS=Bos taurus OX=9913 GN=LTB PE=3 SV=1 CANONICAL=E1BK50-1" }, "locus": { "chromosome": "23", "start_pos": 27705872, "end_pos": 27703526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098345.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098345.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090666.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090666.1" } ] } }, { "isoform_ac": "A0AAA9T488-1", "url": "https://www.uniprot.org/uniprotkb/E1BK50/entry#A0AAA9T488-1", "sequence": { "sequence": "MDWDYMDCTLPGSSVRWNFPGDLELSCHFLLQGILPIHPNPGSCVLWVSQPPEIRTQEGSPAFLPCSFNASQGSLAIGSVTWYRDKVAPGMEVRNETAEFQGRLAPLPSSRFLCDHQAELHIWDTRGRDTGVYVCRVEVLGLGVGTGNGTLLVVEEGPPQLAAGTVLLLRAGFYAFSFLSVAMGSSMYYQGKCECWSRDTWAWRWEGM", "length": 208, "header": "tr|A0AAA9T488-1|E1BK50_BOVIN Computationally mapped isoform of Lymphotoxin-beta OS=Bos taurus OX=9913 GN=LTB PE=3 SV=1 CANONICAL=E1BK50-1" }, "locus": { "chromosome": "23", "start_pos": 27705872, "end_pos": 27673929, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127148.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127148.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093606.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093606.1" } ] } }, { "isoform_ac": "A0AAA9T8Z1-1", "url": "https://www.uniprot.org/uniprotkb/E1BK50/entry#A0AAA9T8Z1-1", "sequence": { "sequence": "MTQRRLDTAMEGCVRCLRSQGVKVLGTPSDMAQMLLFIFIIIRPGSCVLWVSQPPEIRTQEGSPAFLPCSFNASQGSLAIGSVTWYRDKVAPGMEVRNETAEFQGRLAPLPSSRFLCDHQAELHIWDTRGRDTGVYVCRVEVLGLGVGTGNGTLLVVEEGPPQLAAGTVLLLRAGFYAFSFLSVAMGSSMYYQGKCECWSRDTWAWRWEGM", "length": 211, "header": "tr|A0AAA9T8Z1-1|E1BK50_BOVIN Computationally mapped isoform of Lymphotoxin-beta OS=Bos taurus OX=9913 GN=LTB PE=3 SV=1 CANONICAL=E1BK50-1" }, "locus": { "chromosome": "23", "start_pos": 27705872, "end_pos": 27698308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118766.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118766.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093305.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093305.1" } ] } }, { "isoform_ac": "A0AAA9TLX3-1", "url": "https://www.uniprot.org/uniprotkb/E1BK50/entry#A0AAA9TLX3-1", "sequence": { "sequence": "MRPQSSRAAWPLSPLPASSVTTRLSCTSGTPEAVTLESTCAGWRCWAWVSEQGMGPCWWWRKVTGTADPGTQAPAHQRFESGELPEEDSETDLSPRLPAAHLIGAWTTGQGLGWEAKKEEAFLSSGTQFSGAEGLALPQDGLYYLYCHIGYRGRAPPPAVEPLDGSVTLLSRLYRAGGAYGSGTPELLLEGAETVTPVSDPARRHDYGPLWYTSVGFGGLVQLRRGERVYVNISHPDMVDYRRGKTFFGAVMVG", "length": 254, "header": "tr|A0AAA9TLX3-1|E1BK50_BOVIN Computationally mapped isoform of Lymphotoxin-beta OS=Bos taurus OX=9913 GN=LTB PE=3 SV=1 CANONICAL=E1BK50-1" }, "locus": { "chromosome": "23", "start_pos": 27713959, "end_pos": 27705362, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118508.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118508.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097952.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097952.1" } ] } }, { "isoform_ac": 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"sequence": { "sequence": "VATINPPRASYCPCSLTSGYAPRLILLSWLGCPRDGDVLSVSLLVLFSCSCDAVVSRCHQAPSWSYVTGTADPGTQAPAHQRFESGELPEEDSETDLSPRLPAAHLIGAWTTGQGLGWEAKKEEAFLSSGTQFSGAEGLALPQDGLYYLYCHIGYRGRAPPPAVEPLDGSVTLLSRLYRAGGAYGSGTPELLLEGAETVTPVSDPARRHDYGPLWYTSVGFGGLVQLRRGERVYVNISHPDMVDYRRGKTFFGAVMVG", "length": 258, "header": "tr|E1BK50-1|E1BK50_BOVIN Isoform 1 of Lymphotoxin-beta OS=Bos taurus OX=9913 GN=LTB PE=3 SV=3 CANONICAL=E1BK50-1" }, "locus": { "chromosome": "23", "start_pos": 27713959, "end_pos": 27712291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027554.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027554.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027554.6", "url": "https://www.ensembl.org/id/ENSBTAP00000027554.6" } ] } }, { "isoform_ac": "F6QYZ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BK50/entry#F6QYZ6-1", "sequence": { "sequence": "MQISPSAASSFLREGCVRCLRSQGVKVLGTPSDMAQMLLFIFIIIRPGSCVLWVSQPPEIRTQEGSPAFLPCSFNASQGSLAIGSVTWYRDKVAPGMEVRNETAEFQGRLAPLPSSRFLCDHQAELHIWDTRGRDTGVYVCRVEVLGLGVGTGNGTLLVVEEGPPQLAAGTVLLLRAGFYAFSFLSVAMGSSMYYQGKYHCHKGTPCHSLDGL", "length": 213, "header": "tr|F6QYZ6-1|E1BK50_BOVIN Computationally mapped isoform of Lymphotoxin-beta OS=Bos taurus OX=9913 GN=LTB PE=3 SV=1 CANONICAL=E1BK50-1" }, "locus": { "chromosome": "23", "start_pos": 27706002, "end_pos": 27703526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024407.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024407.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024407.5", "url": "https://www.ensembl.org/id/ENSBTAP00000024407.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5668541", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5668541", "resource": "Reactome", "description": "TNFR2 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"Protein" ] }, { "id": "A0AAA9RS90-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RS90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLM4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLM4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZT9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZT9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPF9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPF9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQJ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGA0", "url": "https://www.uniprot.org/uniprotkb/E1BGA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGA0-1", "url": "https://www.uniprot.org/uniprotkb/E1BGA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGTPGRDPWGTPGICYLFGSLLAGLLFPGAAAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADVQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDVIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCVQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVTLSGERLTSGFGYSLAVADLNNDGWTDLVVGAPYFFERQEELGGAVYVYMNEGGHWAGVAPLRLCGSLDSMFGISLAVLGDLNQDGFPDLAVGAPFDGDGKVFIYHGSSLGVVTKPSQVLEGEAVGIKSFGYSLSGGLDADGNHYPDLLVGSLDDTAVLFRARPVLHVSHEVSILPRAIDLEQPNCANGHLVWVQRRAHWSRPHPSSLAPPLPPVTALDYMLDGDTDRRLRGQVPRVTFLSRGPDDPKHQSSGTVWLKHQHDRVCGDTMLQLQENVKDKLRAIVVTLSYGLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRTEIHFLKQGCGEDKICQSNLQLVQARFCARVSDTEFQPLPMDADGTTALFALSGQPVIGLELKVTNLPSDPAQPQADGDDAHEAQLLVTLPAALHYSGVRGLDPVEKPLCLSDENASHVECELGNPMKRGAQVTFYLILSTSGITIETTELEVELLLATISEQELHPVLARARVFIELPLSITGVAIPQQLFFSGVVRGESAMRSERDVGSKVKYEVTVSNQGQSLNTLGSAFLNIMWPHEIANGKWLLYPMRVELEGGQGPGQRGLCSPRPNILQLDVDSRDRRRRELGPPESQEPREQPEPSTSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPAAVAAEGVPWWVILLAVLAGLLVLALLVLLMWKMGFFKRARYPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAGDGHPELGSDGHTVPGTA", "length": 1144, "header": "tr|E1BGA0-1|E1BGA0_BOVIN Isoform 1 of Integrin alpha-7 OS=Bos taurus OX=9913 GN=ITGA7 PE=3 SV=3 CANONICAL=E1BGA0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RS90-1", "url": "https://www.uniprot.org/uniprotkb/E1BGA0/entry#A0AAA9RS90-1", "sequence": { "sequence": "MAGTPGRDPWGTPGICYLFGSLLAGLLFPGAAAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADVQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDVIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGLAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVTLSGERLTSGFGYSLAVADLNNDGWTDLVVGAPYFFERQEELGGAVYVYMNEGGHWAGVAPLRLCGSLDSMFGISLAVLGDLNQDGFPDLAVGAPFDGDGKVFIYHGSSLGVVTKPSQVLEGEAVGIKSFGYSLSGGLDADGNHYPDLLVGSLDDTAVLFRARPVLHVSHEVSILPRAIDLEQPNCANGHLVCMDLRVCFSYIASPSSYSPTVALDYMLDGDTDRRLRGQVPRVTFLSRGPDDPKHQSSGTVWLKHQHDRVCGDTMLQLQENVKDKLRAIVVTLSYGLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRTEIHFLKQGCGEDKICQSNLQLVQARFCARVSDTEFQPLPMDADGTTALFALSGQPVIGLELKVTNLPSDPAQPQADGDDAHEAQLLVTLPAALHYSGVRGLDPVEKPLCLSDENASHVECELGNPMKRGAQVTFYLILSTSGITIETTELEVELLLATISEQELHPVLARARVFIELPLSITGVAIPQQLFFSGVVRGESAMRSERDVGSKVKYEVTVSNQGQSLNTLGSAFLNIMWPHEIANGKWLLYPMRVELEGGQGPGQRGLCSPRPNILQLDVDSRDRRRRELGPPESQEPREQPEPSTSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPAAVAAEGVPWWVILLAVLAGLLVLALLVLLMWKMGFFKRARYPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAGDGHPELGSDGHTVPGTA", "length": 1137, "header": "tr|A0AAA9RS90-1|E1BGA0_BOVIN Computationally mapped isoform of Integrin alpha-7 OS=Bos taurus OX=9913 GN=ITGA7 PE=3 SV=1 CANONICAL=E1BGA0-1" }, "locus": { "chromosome": "5", "start_pos": 57571526, "end_pos": 57548981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133099.2", "url": "https://www.ensembl.org/id/ENSBTAT00000133099.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075342.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075342.1" } ] } }, { "isoform_ac": "A0AAA9SLM4-1", "url": "https://www.uniprot.org/uniprotkb/E1BGA0/entry#A0AAA9SLM4-1", "sequence": { "sequence": "MAGTPGRDPWGTPGICYLFGSLLAGLLFPGAAAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADVQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDVIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCVQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVTLSGERLTSGFGYSLAVADLNNDGWTDLVVGAPYFFERQEELGGAVYVYMNEGGHWAGVAPLRLCGSLDSMFGISLAVLGDLNQDGFPDLAVGAPFDGDGKVFIYHGSSLGVVTKPSQVLEGEAVGIKSFGYSLSGGLDADGNHYPDLLVGSLDDTAVLFRARPVLHVSHEVSILPRAIDLEQPNCANGHLVCMDLRVCFSYIASPSSYSPTVALDYMLDGDTDRRLRGQVPRVTFLSRGPDDPKHQSSGTVWLKHQHDRVCGDTMLQLQENVKDKLRAIVVTLSYGLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRTEIHFLKQGCGEDKICQSNLQLVQARFCARVSDTEFQPLPMDADGTTALFALSGQPVIGLELKVTNLPSDPAQPQADGDDAHEAQLLVTLPAALHYSGVRGLDPVEKPLCLSDENASHVECELGNPMKRGAQVTFYLILSTSGITIETTELEVELLLATISEQELHPVLARARVFIELPLSITGVAIPQQLFFSGVVRGESAMRSERDVGSKVKYEVTVSNQGQSLNTLGSAFLNIMWPHEIANGKWLLYPMRVELEGGQGPGQRGLCSPRPNILQLDVDSRDRRRRELGPPESQEPREQPEPSTSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPAAVAAEGVPWWVILLAVLAGLLVLALLVLLMWKCGFFRRSSQSSSFSTNYHRARLAVQPSAVEAGGPGTVGWDSSSERGTPKPPYPSTMR", "length": 1122, "header": "tr|A0AAA9SLM4-1|E1BGA0_BOVIN Computationally mapped isoform of Integrin alpha-7 OS=Bos taurus OX=9913 GN=ITGA7 PE=3 SV=1 CANONICAL=E1BGA0-1" }, "locus": { "chromosome": "5", "start_pos": 57571356, "end_pos": 57548981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106790.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106790.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083564.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083564.1" } ] } }, { "isoform_ac": "A0AAA9SZT9-1", "url": "https://www.uniprot.org/uniprotkb/E1BGA0/entry#A0AAA9SZT9-1", "sequence": { "sequence": "MAGTPGRDPWGTPGICYLFGSLLAGLLFPGAAAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADVQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDVIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCVQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVTLSGERLTSGFGYSLAVADLNNDGWTDLVVGAPYFFERQEELGGAVYVYMNEGGHWAGVAPLRLCGSLDSMFGISLAVLGDLNQDGFPDLAVGAPFDGDGKVFIYHGSSLGVVTKPSQVLEGEAVGIKSFGYSLSGGLDADGNHYPDLLVGSLDDTAVLFRARPVLHVSHEVSILPRAIDLEQPNCANGHLVCMDLRVCFSYIASPSSYSPTVALDYMLDGDTDRRLRGQVPRVTFLSRGPDDPKHQSSGTVWLKHQHDRVCGDTMLQLQENVKDKLRAIVVTLSYGLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRTEIHFLKQGCGEDKICQSNLQLVQARFCARVSDTEFQPLPMDADGTTALFALSGQPVIGLELKVTNLPSDPAQPQADGDDAHEAQLLVTLPAALHYSGVRGLDPVEKPLCLSDENASHVECELGNPMKRGAQVTFYLILSTSGITIETTELEVELLLATISEQELHPVLARARVFIELPLSITGVAIPQQLFFSGVVRGESAMRSERDVGSKVKYEVTVSNQGQSLNTLGSAFLNIMWPHEIANGKWLLYPMRVELEGGQGPGQRGLCSPRPNILQLDVDSRDRRRRELGPPESQEPREQPEPSTSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPAAVAAEGVPWWVILLAVLAGLLVLALLVLLMWKMGFFKRARYPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAGDGHPELGSDGHTVPGTA", "length": 1141, "header": "tr|A0AAA9SZT9-1|E1BGA0_BOVIN Computationally mapped isoform of Integrin alpha-7 OS=Bos taurus OX=9913 GN=ITGA7 PE=3 SV=2 CANONICAL=E1BGA0-1" }, "locus": { "chromosome": "5", "start_pos": 57571526, "end_pos": 57548981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134133.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134133.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088898.2", "url": "https://www.ensembl.org/id/ENSBTAP00000088898.2" } ] } }, { "isoform_ac": "A0AAA9TPF9-1", "url": "https://www.uniprot.org/uniprotkb/E1BGA0/entry#A0AAA9TPF9-1", "sequence": { "sequence": "MAGTPGRDPWGTPGICYLFGSLLAGLLFPGAAAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADVQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDVIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCVQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGLLFVTNIDSSDPDQLVYKTLDPADRLPGLAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVTLSGERLTSGFGYSLAVADLNNDGWTDLVVGAPYFFERQEELGGAVYVYMNEGGHWAGVAPLRLCGSLDSMFGISLAVLGDLNQDGFPDLAVGAPFDGDGKVFIYHGSSLGVVTKPSQVLEGEAVGIKSFGYSLSGGLDADGNHYPDLLVGSLDDTAVLFRARPVLHVSHEVSILPRAIDLEQPNCANGHLVCMDLRVCFSYIASPSSYSPTVALDYMLDGDTDRRLRGQVPRVTFLSRGPDDPKHQSSGTVWLKHQHDRVCGDTMLQLQENVKDKLRAIVVTLSYGLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRTEIHFLKQGCGEDKICQSNLQLVQARFCARVSDTEFQPLPMDADGTTALFALSGQPVIGLELKVTNLPSDPAQPQADGDDAHEAQLLVTLPAALHYSGVRGLDPVEKPLCLSDENASHVECELGNPMKRGAQVTFYLILSTSGITIETTELEVELLLATISEQELHPVLARARVFIELPLSITGVAIPQQLFFSGVVRGESAMRSERDVGSKVKYEVTVSNQGQSLNTLGSAFLNIMWPHEIANGKWLLYPMRVELEGGQGPGQRGLCSPRPNILQLDVDSRDRRRRELGPPESQEPREQPEPSTSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPAAVAAEGVPWWVILLAVLAGLLVLALLVLLMWKMGFFKRARYPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAGDGHPELGSDGHTVPGTA", "length": 1181, "header": "tr|A0AAA9TPF9-1|E1BGA0_BOVIN Computationally mapped isoform of Integrin alpha-7 OS=Bos taurus OX=9913 GN=ITGA7 PE=3 SV=1 CANONICAL=E1BGA0-1" }, "locus": { "chromosome": "5", "start_pos": 57571526, "end_pos": 57548981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119011.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119011.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098905.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098905.1" } ] } }, { "isoform_ac": "A0ABI0NQJ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BGA0/entry#A0ABI0NQJ0-1", "sequence": { "sequence": "MAGTPGRDPWGTPGICYLFGSLLAGLLFPGAAAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADVQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDVIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVTLSGERLTSGFGYSLAVADLNNDGWTDLVVGAPYFFERQEELGGAVYVYMNEGGHWAGVAPLRLCGSLDSMFGISLAVLGDLNQDGFPDLAVGAPFDGDGKVFIYHGSSLGVVTKPSQVLEGEAVGIKSFGYSLSGGLDADGNHYPDLLVGSLDDTAVLFRARPVLHVSHEVSILPRAIDLEQPNCANGHLVCMDLRVCFSYIASPSSYSPTVALDYMLDGDTDRRLRGQVPRVTFLSRGPDDPKHQSSGTVWLKHQHDRVCGDTMLQLQENVKDKLRAIVVTLSYGLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRTEIHFLKQGCGEDKICQSNLQLVQARFCARVSDTEFQPLPMDADGTTALFALSGQPVIGLELKVTNLPSDPAQPQADGDDAHEAQLLVTLPAALHYSGVRGLDPVEKPLCLSDENASHVECELGNPMKRGAQVTFYLILSTSGITIETTELEVELLLATISEQELHPVLARARVFIELPLSITGVAIPQQLFFSGVVRGESAMRSERDVGSKVKYEVTVSNQGQSLNTLGSAFLNIMWPHEIANGKWLLYPMRVELEGGQGPGQRGLCSPRPNILQLDVDSRDRRRRELGPPESQEPREQPEPSTSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPAAVAAEGVPWWVILLAVLAGLLVLALLVLLMWKMGFFKRARYPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAGDGHPELGSDGHTVPGTA", "length": 1097, "header": "tr|A0ABI0NQJ0-1|A0ABI0NQJ0_BOVIN Computationally mapped isoform of Integrin subunit alpha 7 OS=Bos taurus OX=9913 GN=ITGA7 PE=3 SV=1 CANONICAL=E1BGA0-1" }, "locus": { "chromosome": "5", "start_pos": 57571526, "end_pos": 57548981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147233.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147233.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104493.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104493.1" } ] } }, { "isoform_ac": "E1BGA0-1", "url": "https://www.uniprot.org/uniprotkb/E1BGA0/entry#E1BGA0-1", "sequence": { "sequence": "MAGTPGRDPWGTPGICYLFGSLLAGLLFPGAAAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADVQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDVIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCVQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVTLSGERLTSGFGYSLAVADLNNDGWTDLVVGAPYFFERQEELGGAVYVYMNEGGHWAGVAPLRLCGSLDSMFGISLAVLGDLNQDGFPDLAVGAPFDGDGKVFIYHGSSLGVVTKPSQVLEGEAVGIKSFGYSLSGGLDADGNHYPDLLVGSLDDTAVLFRARPVLHVSHEVSILPRAIDLEQPNCANGHLVWVQRRAHWSRPHPSSLAPPLPPVTALDYMLDGDTDRRLRGQVPRVTFLSRGPDDPKHQSSGTVWLKHQHDRVCGDTMLQLQENVKDKLRAIVVTLSYGLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRTEIHFLKQGCGEDKICQSNLQLVQARFCARVSDTEFQPLPMDADGTTALFALSGQPVIGLELKVTNLPSDPAQPQADGDDAHEAQLLVTLPAALHYSGVRGLDPVEKPLCLSDENASHVECELGNPMKRGAQVTFYLILSTSGITIETTELEVELLLATISEQELHPVLARARVFIELPLSITGVAIPQQLFFSGVVRGESAMRSERDVGSKVKYEVTVSNQGQSLNTLGSAFLNIMWPHEIANGKWLLYPMRVELEGGQGPGQRGLCSPRPNILQLDVDSRDRRRRELGPPESQEPREQPEPSTSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPAAVAAEGVPWWVILLAVLAGLLVLALLVLLMWKMGFFKRARYPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAGDGHPELGSDGHTVPGTA", "length": 1144, "header": "tr|E1BGA0-1|E1BGA0_BOVIN Isoform 1 of Integrin alpha-7 OS=Bos taurus OX=9913 GN=ITGA7 PE=3 SV=3 CANONICAL=E1BGA0-1" }, "locus": { "chromosome": "5", "start_pos": 57571526, "end_pos": 57548981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017145.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017145.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017145.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017145.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:506953", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506953", "resource": "KEGG Pathway" }, { "id": "R-BTA-3000178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3000178", "resource": "Reactome", "description": "ECM proteoglycans" } ], "orthologs": [ { "uniprot_canonical_ac": "Q13683-1", "protein_name": "Integrin alpha-7", "gene_name": "ITGA7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA", "length": 1181 }, "evidence": [ { "id": "E1BGA0", "url": "https://omabrowser.org/oma/group/E1BGA0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61738-1", "protein_name": "Integrin alpha-7", "gene_name": "Itga7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARIPRCDFLRPPGIYYLITSLLAGLFLPPAIAFNLDVMGAIRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDRGANVQKESKENQWLGVSVRSQGAGGKIVTCAHRYESRQRVDQALETRDVIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAATFSPDSHYLVFGAPGTYNWKGTARVELCAQGSPDLAHLDDGPYEAGGEKEQDPRLIPVPANSYLGLLFVTNIDSSDPDQLVYKTLDPADRLTGPAGDLTLNSYLGFSIDSGKGLMRSEELSFVAGAPRANHKGAVVILRKDSATRLIPEVVLSGERLTSGFGYSLAVTDLNNDGWADLIVGAPYFFERQEELGGAVYVYMNQGGHWADISPLRICGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVVKPSQVLEGEAVGIKSFGYSLSGGLDVDGNHYPDLLVGSLADTAALFRARPVLHVSQEIFIDPRAIDLEQPNCADGRLVCVDIKICFSYVAVPSSYSPSVALDYMLDGDTDRRLRGQVPRVTFLSRGLDDLRHQSSGTVWLKHQHDRVCGDTVFQLQENVKDKLRAIVVTLSYGLRTPPLGRQAPGQELPTVAPILNAHQPSTQRTEIHFLKQGCGQDKICQSNLQLERYQFCSRISDTEFQALPMDLDGRTALFALSGQPFIGLELTVTNLPSDPSRPQADGDDAHEAQLLVTLPASLRYSGVRALDSVEKPLCLSNDSASHVECELGNPMKRGAQVTFYLILSTSGITIETTELEVKLLLATISEQELDPVSVRAHVFIELPLSISGVATPQQLFFSGEVKGESAMRSERELGRKVKYEVTVSNQGQSLNTLGSANLNIMWPHEIANGKWLLYPMRVELEGGQGPGKRGICSPRPNILQLDVDSRDRRRRELGQPEPQEPPEKVEPSTSWWPVSSAEKRNMTLDCPRTAKCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYMAVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPMAVVVEGVPWWVILLGVLAGLLVLALLVLLLWKLGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTIQRSNWGNSQWEGSDAHPILAADWHPELGPDGHPVPATA", "length": 1179 }, "evidence": [ { "id": "E1BGA0", "url": "https://omabrowser.org/oma/group/E1BGA0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63258-1", "protein_name": "Integrin alpha-7", "gene_name": "Itga7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARIPRCDFLGLPGICYLLSFLLAGLLLPRASAFNLDVMGAIRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDRGANVQKESKENQWLGVSVRSQGAGGKVVTCAHRYESRQRVDQVLETRDVIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAATFSPDSHYLIFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLTGPAGDLTLNSYLGFSIDSGKGLMRSEELSFVAGAPRANHKGAVVILRKDSASRLIPEVVLSGERLTSGFGYSLAVTDLNSDGWADLIVGAPYFFERQEELGGAVYVYMNQGGHWADISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVTKPSQVLEGEAVGIKSFGYSLSGGLDVDGNHYPDLLVGSLADTAALFRARPVLHVSQEIFIDPRAIDLEQPNCADGRLVCVHVKVCFSYVAVPSSYSPIVVLDYVLDGDTDRRLRGQAPRVTFPGRGPDDLKHQSSGTVSLKHQHDRVCGDTVFQLQENVKDKLRAIVVTLSYGLQTPRLRRQAPDQGLPLVAPILNAHQPSTQRTEIHFLKQGCGDDKICQSNLQLAQAQFCSRISDTEFQALPMDLDGTALFALSGQPFIGLELTVTNLPSDPARPQADGDDAHEAQLLATLPASLRYSGVRTLDSVEKPLCLSNENASHVECELGNPMKRGTQVTFYLILSTSGITIETTELKVELLLATISEQDLHPVSVRAHVFIELPLSISGVATPQQLFFSGKVKGESAMRSERDVGSKVKYEVTVSNQGQSLNTLGSAFLNIMWPHEIANGKWLLYPMRVELEGGQGPEKKGICSPRPNILHLDVDSRDRRRRELGQPEPQEPPEKVEPSTSWWPVSSAEKRNVTLDCAQGTAKCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYMSVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPVAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKLGFFKRAKHPEATVPQYHAVKILREDRQQFKEEKTGTIQRSNWGNSQWEGSDAHPILAADWHPELGPDGHPVSVTA", "length": 1135 }, "evidence": [ { "id": "E1BGA0", "url": "https://omabrowser.org/oma/group/E1BGA0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "E1BGA0", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" } ], "pmid": "" }, { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "E1BGA0", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" } ], "pmid": "" }, { "name": "heterotypic cell-cell adhesion", "id": "GO:0034113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034113", "evidence": [ { "database": "UniProtKB", "id": "E1BGA0", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" } ], "pmid": "" }, { "name": "endodermal cell differentiation", "id": "GO:0035987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035987", "evidence": [ { "database": "UniProtKB", "id": "E1BGA0", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "E1BGA0", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" } ], "pmid": "" }, { "name": "leukocyte migration", "id": "GO:0050900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050900", "evidence": [ { "database": "UniProtKB", "id": "E1BGA0", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "integrin complex", "id": "GO:0008305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008305", "evidence": [ { "database": "UniProtKB", "id": "E1BGA0", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E1BGA0", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BGA0", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "E1BGA0", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1008, "end_pos": 1010, "annotation": "n_glycosylation_sequon" }, { "start_pos": 749, "end_pos": 751, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" }, { "start_pos": 952, "end_pos": 954, "annotation": "n_glycosylation_sequon" }, { "start_pos": 988, "end_pos": 990, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" }, { "id": "PF08441", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08441" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrin alpha first immunoglubulin-like", "eco_id": "ECO_0000259", "start_pos": 475, "end_pos": 642, "start_aa": "Ala", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BGA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" }, { "id": "PF20805", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrin alpha second immunoglobulin-like", "eco_id": "ECO_0000259", "start_pos": 644, "end_pos": 806, "start_aa": "Cys", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BGA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA0" }, { "id": "PF20806", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20806" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrin alpha third immunoglobulin-like", "eco_id": "ECO_0000259", "start_pos": 814, "end_pos": 1032, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1008, "end_pos": 1010 }, { "start_pos": 749, "end_pos": 751 }, { "start_pos": 86, "end_pos": 88 }, { "start_pos": 952, "end_pos": 954 }, { "start_pos": 988, "end_pos": 990 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEI2-1", "uniprot_ac": "E1BEI2", "uniprot_id": "E1BEI2_BOVIN", "mass": { "chemical_mass": 24888.0, "monoisotopic_mass": 24888.0 }, "refseq": {}, "gene_names": [ { "name": "SPCS2", "type": "recommended", "evidence": [ { "id": "E1BEI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI2" } ] } ], "protein_names": [ { "name": "Signal peptidase complex subunit 2", "type": "recommended", "evidence": [ { "id": "E1BEI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T485", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T485#function" }, { "database": "UniProtKB", "id": "RU368033", "url": "https://www.uniprot.org/uniprotkb/RU368033#function" }, { "database": "UniProtKB", "id": "ARBA00045608", "url": "https://www.uniprot.org/uniprotkb/ARBA00045608#function" }, { "database": "UniProtKB", "id": "E1BEI2", "url": "https://www.uniprot.org/uniprotkb/E1BEI2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEI2", "url": "https://www.uniprot.org/uniprotkb/E1BEI2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPCS2", "url": "https://www.uniprot.org/uniprotkb/E1BEI2", "locus": { "chromosome": "15", "start_pos": 54247479, "end_pos": 54223233, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006644", "url": "https://www.ensembl.org/id/ENSBTAG00000006644" } ] } } ], "crossref": [ { "id": "E1BEI2", "url": "https://alphafold.ebi.ac.uk/entry/E1BEI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006644", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006644", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "INKWDGT", "url": "https://omabrowser.org/oma/group/INKWDGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEI2", "url": "https://www.orthodb.org/?gene=E1BEI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13085", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13085", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13085:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13085:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-422085", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-422085", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9768727", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9768727", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9T485", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T485", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T485-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T485-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEI2", "url": "https://www.uniprot.org/uniprotkb/E1BEI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEI2-1", "url": "https://www.uniprot.org/uniprotkb/E1BEI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAASQGGRAGGGGGSSGAGGGSGCGTGSSRSGLLDKWKIDDKPVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLIICTISCFFAIVALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLATERKIK", "length": 226, "header": "tr|E1BEI2-1|E1BEI2_BOVIN Isoform 1 of Signal peptidase complex subunit 2 OS=Bos taurus OX=9913 GN=SPCS2 PE=1 SV=2 CANONICAL=E1BEI2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T485-1", "url": "https://www.uniprot.org/uniprotkb/E1BEI2/entry#A0AAA9T485-1", "sequence": { "sequence": "MAAAASQGGRAGGGGGSSGAGGGSGCGTGSSRSGLLDKWKIDDKPVKIDKWDGSAVKNSLDDSAKKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLATERKIK", "length": 157, "header": "tr|A0AAA9T485-1|E1BEI2_BOVIN Computationally mapped isoform of Signal peptidase complex subunit 2 OS=Bos taurus OX=9913 GN=SPCS2 PE=1 SV=2 CANONICAL=E1BEI2-1" }, "locus": { "chromosome": "15", "start_pos": 54246475, "end_pos": 54223332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097775.2", "url": "https://www.ensembl.org/id/ENSBTAT00000097775.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091472.2", "url": "https://www.ensembl.org/id/ENSBTAP00000091472.2" } ] } }, { "isoform_ac": "E1BEI2-1", "url": "https://www.uniprot.org/uniprotkb/E1BEI2/entry#E1BEI2-1", "sequence": { "sequence": "MAAAASQGGRAGGGGGSSGAGGGSGCGTGSSRSGLLDKWKIDDKPVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLIICTISCFFAIVALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLATERKIK", "length": 226, "header": "tr|E1BEI2-1|E1BEI2_BOVIN Isoform 1 of Signal peptidase complex subunit 2 OS=Bos taurus OX=9913 GN=SPCS2 PE=1 SV=2 CANONICAL=E1BEI2-1" }, "locus": { "chromosome": "15", "start_pos": 54246475, "end_pos": 54223332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008726.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008726.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008726.5", "url": "https://www.ensembl.org/id/ENSBTAP00000008726.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-422085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-422085", "resource": "Reactome", "description": "Synthesis, secretion, and deacylation of Ghrelin" }, { "id": "R-BTA-9768727", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9768727", "resource": "Reactome", "description": "Regulation of CDH1 posttranslational processing and trafficking to plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZD11-1", "protein_name": "Signal peptidase complex subunit 2", "gene_name": "Spcs2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAASQGGRSGGGGGSSGPGGGPSCGTSSSRSGLLDKWKIDDKPVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLTICTISCFFAIVALIWDYMHPFPESKPVLALCVVSYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLATERKIK", "length": 226 }, "evidence": [ { "id": "E1BEI2", "url": "https://omabrowser.org/oma/group/E1BEI2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P58684-1", "protein_name": "Signal peptidase complex subunit 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEKKTESTNKNVKKANLLDHHSIKHILDESVSDIVTSRGYKEDVRLSNLKLILGTIIIVVALVAQFYNKKFPENRDFLIGCIALYVVLNAVLQLILYTKEKNAILFTYPPEGSFTSTGLVVSSKLPRFSDQYTLTIDSADPKSISAGKSVQLTKSVTQWFTKDGVLVEGLFWKDVEALIKNYAEEEPKKKK", "length": 192 }, "evidence": [ { "id": "E1BEI2", "url": "https://omabrowser.org/oma/group/E1BEI2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q15005-1", "protein_name": "Signal peptidase complex subunit 2", "gene_name": "SPCS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAVQGGRSGGSGGCSGAGGASNCGTGSGRSGLLDKWKIDDKPVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLTICTISCFFAIVALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLAIERKIK", "length": 226 }, "evidence": [ { "id": "E1BEI2", "url": "https://omabrowser.org/oma/group/E1BEI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55E35-1", "protein_name": "Signal peptidase complex subunit 2", "gene_name": "spcs2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSTTTTTTTTEKPIQVTLYDSNTIKQTLDDSIVKYVTSALSYTQNQKLNYTKVLFGLIGCTLAAIAQFYPIPFPKNKPVLILCVALYVVISLILYYINIFIQKDYILQASKSNDEIKVATVLQKYDPNYQVKIENAKNSSINVPFSKSIDLYFDTKGTFLESNFHNDLSVQFKKFAKLNVKDK", "length": 183 }, "evidence": [ { "id": "E1BEI2", "url": "https://omabrowser.org/oma/group/E1BEI2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9CYN2-1", "protein_name": "Signal peptidase complex subunit 2", "gene_name": "Spcs2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASASQGGRSGGGGGSSGAGGGPSCGTSSSRSGLLDKWKIDDKPVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLTICTISCFFAIVALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLATERKIK", "length": 226 }, "evidence": [ { "id": "E1BEI2", "url": "https://omabrowser.org/oma/group/E1BEI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VYY2-1", "protein_name": "Signal peptidase complex subunit 2", "gene_name": "Spase25", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKKDEKSQQGEELVKVNKWDGSAVKHALDDAVKTCLLGDRPQLKEQFGLVNTRLALCALAVSVAIMAHAWDFTHPFPESRPVLLFSVLAYFALLGILTLHSSFREKGTFAVALQKDKERERLWEASSDMRKYDDKYLLTLSVRDTKNGKRREQSSNKSCAAFIDQNGIVLDNLVANEVNRLFNALAADKKNASSLSSN", "length": 199 }, "evidence": [ { "id": "E1BEI2", "url": "https://omabrowser.org/oma/group/E1BEI2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "E1BEI2", "url": "https://www.uniprot.org/uniprotkb/E1BEI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal peptide processing", "id": "GO:0006465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006465", "evidence": [ { "database": "UniProtKB", "id": "E1BEI2", "url": "https://www.uniprot.org/uniprotkb/E1BEI2" } ], "pmid": "" }, { "name": "protein targeting to ER", "id": "GO:0045047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045047", "evidence": [ { "database": "UniProtKB", "id": "E1BEI2", "url": "https://www.uniprot.org/uniprotkb/E1BEI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "signal peptidase complex", "id": "GO:0005787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005787", "evidence": [ { "database": "UniProtKB", "id": "E1BEI2", "url": "https://www.uniprot.org/uniprotkb/E1BEI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEI2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 226, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEI2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEI2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BF09-1", "uniprot_ac": "E1BF09", "uniprot_id": "E1BF09_BOVIN", "mass": { "chemical_mass": 28985.0, "monoisotopic_mass": 28985.0 }, "refseq": { "ac": "NP_001179959", "name": "transmembrane protein 150A precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179959" }, "gene_names": [ { "name": "TMEM150A", "type": "recommended", "evidence": [ { "id": "E1BF09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF09" } ] }, { "name": "TMEM150A", "type": "synonym", "evidence": [ { "id": "NP_001179959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179959" } ] }, { "name": "TMEM150", "type": "synonym", "evidence": [ { "id": "NP_001179959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179959" } ] } ], "protein_names": [ { "name": "Transmembrane protein 150A", "type": "recommended", "evidence": [ { "id": "E1BF09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF09/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 150", "type": "synonym", "evidence": [ { "id": "E1BF09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF09/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 150A precursor", "type": "synonym", "evidence": [ { "id": "NP_001179959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179959" } ] }, { "name": "transmembrane protein 150", "type": "synonym", "evidence": [ { "id": "NP_001179959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179959" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BF09", "url": "https://www.uniprot.org/uniprotkb/E1BF09" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM150A", "url": "https://www.uniprot.org/uniprotkb/E1BF09", "locus": { "chromosome": "11", "start_pos": 49411187, "end_pos": 49406589, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018289", "url": "https://www.ensembl.org/id/ENSBTAG00000018289" } ] } } ], "crossref": [ { "id": "E1BF09", "url": "https://alphafold.ebi.ac.uk/entry/E1BF09", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018289", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018289", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515742", "url": "https://www.ncbi.nlm.nih.gov/gene/515742", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515742", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515742", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DPAKHGY", "url": "https://omabrowser.org/oma/group/DPAKHGY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BF09", "url": "https://www.orthodb.org/?gene=E1BF09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179959", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179959", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T5Y8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDE2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF09", "url": "https://www.uniprot.org/uniprotkb/E1BF09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF09-1", "url": "https://www.uniprot.org/uniprotkb/E1BF09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAWILLPVSLSAFSITGLWTVYAMAVMNHHVCPVENWSYNESCSPDPTEQGGPKTCCTLDDIPLISKCGSYPPESCLFSLIGNLGAFMVALICLLRYGQLLEQSRHSWVNTTTLITGCTNAAGLVVVGNFQVDHAKSLHYVGTGVAFTAGLLFVCLHCALSYHGATAPQDLAVAYLRIVLATIAFVTLILSGVFFIHESSQLQHGAALCEWVFVIDILIFYGTFSYEFGAVSSDTLVAALQPTPGRACKSSGSSSTSTHLNCSPESVAMI", "length": 271, "header": "tr|E1BF09-1|E1BF09_BOVIN Isoform 1 of Transmembrane protein 150A OS=Bos taurus OX=9913 GN=TMEM150A PE=3 SV=1 CANONICAL=E1BF09-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T5Y8-1", "url": "https://www.uniprot.org/uniprotkb/E1BF09/entry#A0AAA9T5Y8-1", "sequence": { "sequence": "TCAPWRTGLTTNLALLTPRSKGAPRPAAPWMTSPSSVALICLLRYGQLLEQSRHSWVNTTTLITGCTNAAGLVVVGNFQVDHAKSLHYVGTGVAFTAGLLFVCLHCALSYHGATAPQDLAVAYLRIVLATIAFVTLILSGVFFIHESSQLQHGAALCEWVFVIDILIFYGTFSYEFGAVSSDTLVAALQPTPGRACKSSGSSSTSTHLNCSPESVAMI", "length": 218, "header": "tr|A0AAA9T5Y8-1|E1BF09_BOVIN Computationally mapped isoform of Transmembrane protein 150A OS=Bos taurus OX=9913 GN=TMEM150A PE=3 SV=1 CANONICAL=E1BF09-1" }, "locus": { "chromosome": "11", "start_pos": 49410129, "end_pos": 49407816, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105291.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105291.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091178.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091178.1" } ] } }, { "isoform_ac": "A0AAA9TDE2-1", "url": "https://www.uniprot.org/uniprotkb/E1BF09/entry#A0AAA9TDE2-1", "sequence": { "sequence": "MAHSTDSLTLKLPSSLFPLGPGLPRARRRHWASLLFSDIGSACPLPRSYNESCSPDPTEQGGPKTCCTLDDIPLISKCGSYPPESCLFSLIGNLGAFMVALICLLRYGQLLEQSRHSWVNTTTLITGCTNAAGLVVVGNFQVDHAKSLHYVGTGVAFTAGLLFVCLHCALSYHGATAPQDLAVAYLRIVLATIAFVTLILSGVFFIHESSQLQHGAALCEWVFVIDILIFYGTFSYEFGAVSSDTLVAALQPTPGRACKSSGSSSTSTHLNCSPESVAMI", "length": 280, "header": "tr|A0AAA9TDE2-1|E1BF09_BOVIN Computationally mapped isoform of Transmembrane protein 150A OS=Bos taurus OX=9913 GN=TMEM150A PE=3 SV=1 CANONICAL=E1BF09-1" }, "locus": { "chromosome": "11", "start_pos": 49410129, "end_pos": 49407840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108726.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108726.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094886.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094886.1" } ] } }, { "isoform_ac": "E1BF09-1", "url": "https://www.uniprot.org/uniprotkb/E1BF09/entry#E1BF09-1", "sequence": { "sequence": "MTAWILLPVSLSAFSITGLWTVYAMAVMNHHVCPVENWSYNESCSPDPTEQGGPKTCCTLDDIPLISKCGSYPPESCLFSLIGNLGAFMVALICLLRYGQLLEQSRHSWVNTTTLITGCTNAAGLVVVGNFQVDHAKSLHYVGTGVAFTAGLLFVCLHCALSYHGATAPQDLAVAYLRIVLATIAFVTLILSGVFFIHESSQLQHGAALCEWVFVIDILIFYGTFSYEFGAVSSDTLVAALQPTPGRACKSSGSSSTSTHLNCSPESVAMI", "length": 271, "header": "tr|E1BF09-1|E1BF09_BOVIN Isoform 1 of Transmembrane protein 150A OS=Bos taurus OX=9913 GN=TMEM150A PE=3 SV=1 CANONICAL=E1BF09-1" }, "locus": { "chromosome": "11", "start_pos": 49410129, "end_pos": 49407305, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024342.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024342.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024342.5", "url": "https://www.ensembl.org/id/ENSBTAP00000024342.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 244, "start_aa": "Thr", "end_pos": 244, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr244", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:515742", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515742", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AF19-1", "protein_name": "Transmembrane protein 150A", "gene_name": "TMEM150A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVMNHHVCPVENWSYNESCSPDPTEQGGPKTCCTLDDVPLISRCGTYPPESCLFSLIGNVGAFMVALICLLRYGQLLEQGRHSWVNTTTLITGCTNAAGLVLLGNFQVDHAKALHYVGTGVAFTTGLLFVCLHCALSYHGATAPQDLAVAYLRIVLAAIAFVTLILSGVFFIHESSQLQHGAALCEWMFVIDILIFYGTFSYEFGVVSSETLVAALQPAPGRACKSSGSSSASTHLNCAPESVAMI", "length": 247 }, "evidence": [ { "id": "E1BF09", "url": "https://omabrowser.org/oma/group/E1BF09/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HPY7-1", "protein_name": "Transmembrane protein 150A", "gene_name": "Tmem150a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTAWILLPVSLSAFSITGIWTVYAMAVMNRHVCPVENWSYNESCSPDPAEQGGPKTCCTLDDVPLISKCGTYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWINTTALITGCTNAAGLVVVGNFQVDHAKSLHYIGAGVAFPAGLLFVCLQCVLFYHGATTTLDLAMAYLRSVLAVIAFITLVLSGVFFLHESSQLQHGAALCEWVFVLDILIFYGTFSYEFGAVSSDTLVAALQPAPGRACKSSGSSSTSTHLNCAPESIAMI", "length": 271 }, "evidence": [ { "id": "E1BF09", "url": "https://omabrowser.org/oma/group/E1BF09/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q86TG1-1", "protein_name": "Transmembrane protein 150A", "gene_name": "TMEM150A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAWILLPVSLSAFSITGIWTVYAMAVMNHHVCPVENWSYNESCPPDPAEQGGPKTCCTLDDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTALITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSSDTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI", "length": 271 }, "evidence": [ { "id": "E1BF09", "url": "https://omabrowser.org/oma/group/E1BF09/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91WN2-1", "protein_name": "Transmembrane protein 150A", "gene_name": "Tmem150a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAWILLPVSLSAFSITGIWTVYAMAVMNRHVCPVENWSYNESCSPDPAEQGGPKSCCTLDDVPLISKCGTYPPESCLFSLIGNMGAVMVALICLLRYGQLLEQSRHSWINTTALITGCTNAAGLVVVGNFQVDHAKSLHYIGTGVAFTAGLLFVCLHCVLFYHGATTPLDMAMAYLRSVLAVIAFITLVLSGVFFLHESSQLQHGAALCEWVFVLDILIFYGTFSYEFGTISSDTLVAALQPAPGRACKSSGSSSTSTHLNCAPESIAMI", "length": 271 }, "evidence": [ { "id": "E1BF09", "url": "https://omabrowser.org/oma/group/E1BF09/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QZE9-1", "protein_name": "Transmembrane protein 150A", "gene_name": "Tmem150a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAWILLPVSLSAFSITGIWTVYAMAVMNRHVCPVENWSYNDSCSPDPAEQGGPKTCCTLDDVPLISKCGTYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQNRHSWINTTALITGCTNAAGLVVVGNFQVDHAKSLHYIGAGVAFPAGLLFVCLHCVLFYHGATTPLDMAMAYLRSVLAVIAFVTLVLSGVFFLHESSELQHGAALCEWVFVLDILIFYGTFSYEFGAVSSDTLVAALQPAPGRACKSSGSSSTSTHLNCAPESIAMI", "length": 271 }, "evidence": [ { "id": "E1BF09", "url": "https://omabrowser.org/oma/group/E1BF09/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BF09", "url": "https://www.uniprot.org/uniprotkb/E1BF09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "E1BF09", "url": "https://www.uniprot.org/uniprotkb/E1BF09" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "E1BF09", "url": "https://www.uniprot.org/uniprotkb/E1BF09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BF09-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 271, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BF09-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BF09" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BF09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF09" }, { "id": "PF10277", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10277" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CWH43-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 231, "start_aa": "Trp", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 244 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 262, "end_pos": 264 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK60-1", "uniprot_ac": "E1BK60", "uniprot_id": "E1BK60_BOVIN", "mass": { "chemical_mass": 51890.0, "monoisotopic_mass": 51890.0 }, "refseq": { "ac": "XP_024852362", "name": "palmitoyltransferase ZDHHC14 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852362" }, "gene_names": [ { "name": "ZDHHC14", "type": "recommended", "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ] }, { "name": "ZDHHC14", "type": "synonym", "evidence": [ { "id": "XP_024852362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852362" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60/entry#names_and_taxonomy" } ] }, { "name": "palmitoyltransferase ZDHHC14 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024852362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852362" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK60", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZDHHC14", "url": "https://www.uniprot.org/uniprotkb/E1BK60", "locus": { "chromosome": "9", "start_pos": 94302851, "end_pos": 94011819, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018464", "url": "https://www.ensembl.org/id/ENSBTAG00000018464" } ] } } ], "crossref": [ { "id": "E1BK60", "url": "https://alphafold.ebi.ac.uk/entry/E1BK60", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018464", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018464", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "517451", "url": "https://www.ncbi.nlm.nih.gov/gene/517451", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BK60", "url": "https://www.orthodb.org/?gene=E1BK60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22883", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22883:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024852362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852362", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9T7L1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7L1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK60", "url": "https://www.uniprot.org/uniprotkb/E1BK60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK60-1", "url": "https://www.uniprot.org/uniprotkb/E1BK60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPGGGGPMKDCEYSQISTHSSSPMESPHKKKKIAARRKWEVFPGRNKFFCNGRIMMARQTGVFYLTLVLILVTSGLFFAFDCPYLAVKITPAIPVVGGILFFFVMGTLLRTSFSDPGVLPRATPDEAADLERQIGNPEDIANGTSSGGYRPPPRTKEVIINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVERFDHHCPWVGNCVGKRNYRFFYMFILSLSFLTVFIFAFVITHVILRSQQAGFLNALKDSPASVLEAVVCFFSVWSIVGLSGFHTYLISSNQTTNEDIKGSWSNKRGKENYNPYSYGNIFTNCCVALCGPISPSLIDRRGYIQPDTPQPAAPSNGMATYGATQSQSDMAAATPLLQSEPSLTSDELHLPGKPGLGTPCASLTLGPPTPPSSMPNLAAEAALTDILPLKDEHVGHQFLTPDEAPSPPTMLAGSPLAHSRTMHVLGLASQDSLHEDSVRGLVKLSSV", "length": 477, "header": "tr|E1BK60-1|E1BK60_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC14 PE=3 SV=3 CANONICAL=E1BK60-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T7L1-1", "url": "https://www.uniprot.org/uniprotkb/E1BK60/entry#A0AAA9T7L1-1", "sequence": { "sequence": "MPPGGGGPMKDCEYSQISTHSSSPMESPHKKKKIAARRKWEVFPGRNKFFCNGRIMMARQTGVFYLTLVLILVTSGLFFAFDCPYLAVKITPAIPVVGGILFFFVMGTLLRTSFSDPGVLPRATPDEAADLERQIDIANGTSSGGYRPPPRTKEVIINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVERFDHHCPWVGNCVGKRNYRFFYMFILSLSFLTVFIFAFVITHVILRSQQAGFLNALKDSPASVLEAVVCFFSVWSIVGLSGFHTYLISSNQTTNEDIKGSWSNKRGKENYNPYSYGNIFTNCCVALCGPISPSLIDRRGYIQPDTPQPAAPSNGMATYGATQSQSDMGLHTSPWSGRHGPPSGANLSKEVFLEATQCGPSAVCRPESPTTEAMTNRLRHRYVFRKEAVTLQDLGVESMRRPGAGSQECPLPVSLGTR", "length": 446, "header": "tr|A0AAA9T7L1-1|E1BK60_BOVIN Computationally mapped isoform of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC14 PE=3 SV=1 CANONICAL=E1BK60-1" }, "locus": { "chromosome": "9", "start_pos": 94288217, "end_pos": 94012018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108335.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108335.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092761.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092761.1" } ] } }, { "isoform_ac": "E1BK60-1", "url": "https://www.uniprot.org/uniprotkb/E1BK60/entry#E1BK60-1", "sequence": { "sequence": "MPPGGGGPMKDCEYSQISTHSSSPMESPHKKKKIAARRKWEVFPGRNKFFCNGRIMMARQTGVFYLTLVLILVTSGLFFAFDCPYLAVKITPAIPVVGGILFFFVMGTLLRTSFSDPGVLPRATPDEAADLERQIGNPEDIANGTSSGGYRPPPRTKEVIINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVERFDHHCPWVGNCVGKRNYRFFYMFILSLSFLTVFIFAFVITHVILRSQQAGFLNALKDSPASVLEAVVCFFSVWSIVGLSGFHTYLISSNQTTNEDIKGSWSNKRGKENYNPYSYGNIFTNCCVALCGPISPSLIDRRGYIQPDTPQPAAPSNGMATYGATQSQSDMAAATPLLQSEPSLTSDELHLPGKPGLGTPCASLTLGPPTPPSSMPNLAAEAALTDILPLKDEHVGHQFLTPDEAPSPPTMLAGSPLAHSRTMHVLGLASQDSLHEDSVRGLVKLSSV", "length": 477, "header": "tr|E1BK60-1|E1BK60_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC14 PE=3 SV=3 CANONICAL=E1BK60-1" }, "locus": { "chromosome": "9", "start_pos": 94301847, "end_pos": 94012018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024571.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024571.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024571.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024571.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BK60", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BK60", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BK60", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "E1BK60", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "E1BK60", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3X756-1", "E1BPA5-1", "F1MVC6-1", "E1B987-1", "E1BJK1-1", "F6R785-1", "A0AAA9TDW4-1", "A0AAA9TVJ9-1", "A0AAA9TM40-1", "E1B6X9-1", "E1BKA0-1", "E1BK60-1", "Q58CU4-1", "A2VDT6-1", "A0AAF6ZH94-1", "A0AAA9RZ07-1", "Q0VC89-1", "E1BLT8-1", "G3MXF3-1", "P15103-1", "Q2HJ95-1", "Q58DA8-1", "A0A3Q1M794-1", "A0A3Q1LVW6-1", "Q58DT3-1", "A0A3Q1M403-1", "A0ABI0NXA5-1" ], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LVW6", "gene_name": "ZDHHC13", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1LVW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVW6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1LVW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVW6" } ] } ] }, { "uniprot_ac": "A0A3Q1M403", "gene_name": "", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] } ] }, { "uniprot_ac": "A0A3Q1M794", "gene_name": "ZDHHC3", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M794" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1M794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M794" } ] } ] }, { "uniprot_ac": "A0AAA9RZ07", "gene_name": "ZDHHC8", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9RZ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ07" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9RZ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ07" } ] } ] }, { "uniprot_ac": "A0AAA9TDW4", "gene_name": "ZDHHC7", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TDW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDW4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TDW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDW4" } ] } ] }, { "uniprot_ac": "A0AAA9TM40", "gene_name": "ZDHHC18", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM40" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM40" } ] } ] }, { "uniprot_ac": "A0AAA9TVJ9", "gene_name": "ZDHHC23", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TVJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TVJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ9" } ] } ] }, { "uniprot_ac": "A0AAF6ZH94", "gene_name": "ZDHHC9", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAF6ZH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZH94" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAF6ZH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZH94" } ] } ] }, { "uniprot_ac": "A0ABI0NXA5", "gene_name": "ZDHHC15", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0ABI0NXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0ABI0NXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5" } ] } ] }, { "uniprot_ac": "A2VDT6", "gene_name": "ZDHHC21", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A2VDT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A2VDT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT6" } ] } ] }, { "uniprot_ac": "E1B6X9", "gene_name": "ZDHHC12", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1B6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1B6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X9" } ] } ] }, { "uniprot_ac": "E1B987", "gene_name": "ZDHHC22", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ] } ] }, { "uniprot_ac": "E1BJK1", "gene_name": "ZDHHC17", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ] } ] }, { "uniprot_ac": "E1BK60", "gene_name": "ZDHHC14", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ] } ] }, { "uniprot_ac": "E1BKA0", "gene_name": "ZDHHC4", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BKA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA0" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BKA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA0" } ] } ] }, { "uniprot_ac": "E1BLT8", "gene_name": "ZDHHC5", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BLT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLT8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BLT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLT8" } ] } ] }, { "uniprot_ac": "E1BPA5", "gene_name": "ZDHHC24", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BPA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA5" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BPA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA5" } ] } ] }, { "uniprot_ac": "F1MVC6", "gene_name": "", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "F1MVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "F1MVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC6" } ] } ] }, { "uniprot_ac": "F6R785", "gene_name": "ZDHHC1", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ] } ] }, { "uniprot_ac": "G3MXF3", "gene_name": "ZDHHC2", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "G3MXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXF3" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "G3MXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXF3" } ] } ] }, { "uniprot_ac": "G3X756", "gene_name": "", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "G3X756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "G3X756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ] } ] }, { "uniprot_ac": "P15103", "gene_name": "GLUL", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] }, { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] } ] }, { "uniprot_ac": "Q0VC89", "gene_name": "ZDHHC20", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] } ] }, { "uniprot_ac": "Q2HJ95", "gene_name": "ZDHHC6", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q2HJ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ95" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q2HJ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ95" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q2HJ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ95" } ] } ] }, { "uniprot_ac": "Q58CU4", "gene_name": "ZDHHC16", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q58CU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58CU4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q58CU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58CU4" } ] } ] }, { "uniprot_ac": "Q58DA8", "gene_name": "ZDHHC9", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q58DA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DA8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q58DA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DA8" } ] } ] }, { "uniprot_ac": "Q58DT3", "gene_name": "ZDHHC4", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q58DT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DT3" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q58DT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DT3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BK60-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 477, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BK60-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BK60" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60" }, { "id": "PF01529", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Palmitoyltransferase DHHC", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 291, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.225", "ec_name": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "2.3.1.225", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225" }, { "id": "2.3.1.225", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.225" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 399 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 }, { "start_pos": 283, "end_pos": 285 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHZ3-1", "uniprot_ac": "E1BHZ3", "uniprot_id": "E1BHZ3_BOVIN", "mass": { "chemical_mass": 84200.0, "monoisotopic_mass": 84200.0 }, "refseq": { "ac": "XP_005212882", "name": "protein FAM161A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212882" }, "gene_names": [ { "name": "FAM161A", "type": "recommended", "evidence": [ { "id": "E1BHZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ] }, { "name": "FAM161A", "type": "synonym", "evidence": [ { "id": "XP_005212882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212882" } ] } ], "protein_names": [ { "name": "Protein FAM161A", "type": "recommended", "evidence": [ { "id": "E1BHZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3/entry#names_and_taxonomy" } ] }, { "name": "protein FAM161A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005212882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212882" } ] } ], "function": [ { "annotation": "Involved in ciliogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TB97", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB97#function" }, { "database": "UniProtKB", "id": "ARBA00037165", "url": "https://www.uniprot.org/uniprotkb/ARBA00037165#function" }, { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM161A", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3", "locus": { "chromosome": "11", "start_pos": 60420699, "end_pos": 60449802, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009290", "url": "https://www.ensembl.org/id/ENSBTAG00000009290" } ] } } ], "crossref": [ { "id": "E1BHZ3", "url": "https://alphafold.ebi.ac.uk/entry/E1BHZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009290", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009290", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "532883", "url": "https://www.ncbi.nlm.nih.gov/gene/532883", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532883", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532883", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR21501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21501:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21501:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005212882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212882", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TB97", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB97-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHZ3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASHRAAKLAASSLQTPVNPNTRARVAQYERKDPLNSLSAAAAAMEEEEEEEEKEAAARLARAPADFNTSISRVNEQKHISHEDFVNFSDIYHSNEEYFRKLEELKAAHIETMAKLEKLYQSKLNLKEVQPAVTREEAASVSSGSLSEKNSYHPVSLMTSISEPDLSQSSSLIVSSSEEELPNLEKKYSEKSGMMTYAKELINNMWTNFSVEDYIQHEDVNLPVLEKQRKKPKEWVPRITVPEPFQMMVREQKKKEENMKSKSDIEMVHKLLKKQEEESECKKKFRANPVPAFVFLPLYHDIVKQNEVRRRAMKERNKEALLASQKPFKFVAREEQKQAVREKQLKDFFKSKKKTNRFKARPVPRSTYSSTINDKLTEEELYKNMRAQQRTQDFLQNPSPRPYSPARRSFATRKSRGPEQAEKSKYKHRVRRQAADSEDLPERYQKHHSEQKYRKFLTVCEPCDLQAASHSATKREKILADIEADEENLKETRWPYLSPRRKSPVRAANTKPAPCSCNPPTPTVSSRGREQATRRSLEEKKMLEEERHRILTKQKQRMKELQKLLTTRAKAYDSHESLAQMSKSRIKALRKSEKERMREYRRELEEREEKLKNRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKIFEYFSNQEMKNFTEDKESFNEEEKIEERENGEENYLTDTNSQDSCKETDEVNEENGEEKCVEE", "length": 721, "header": "tr|E1BHZ3-1|E1BHZ3_BOVIN Isoform 1 of Protein FAM161A OS=Bos taurus OX=9913 GN=FAM161A PE=3 SV=3 CANONICAL=E1BHZ3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TB97-1", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3/entry#A0AAA9TB97-1", "sequence": { "sequence": "MAASHRAAKLAASSLQTPVNPNTRARVAQYERKDPLNSLSAAAAAMEEEEEEEEKEAAARLARAPADFNTSISRVNEQKHISHEDFVNFSDIYHSNEEYFRKLEELKAAHIETMAKLEKLYQSKLNLKEVQPAVTREEAASVSSGSLSEKNSYHPVSLMTSISEPDLSQSSSLIVSSSEEELPNLEKKYSEKSGMMTYAKELINNMWTNFSVEDYIQHEDVNLPVLEKQRKKPKEWVPRITVPEPFQMMVREQKKKEENMKSKSDIEMVHKLLKKQEEESECKKKFRANPVPAFVFLPLYHDIVKQNEVRRRAMKERNKEALLASQKPFKFVAREEQKQAVREKQLKDFFKSKKKTNRFKARPVPRSTYSSTINDKLTEEELYKNMRAQQRTQDFLQNPSPRPYSPARRSFATRKSRGPEQAEKSKYKHRVRRQAADSEDLPERYQKHHSEQKYRKFLTVCEPCDLQAASHSATKREKILADIEADEENLKETRWPYLSPRRKSPVRAANTKPAPCSCNPPTPTVSSRGREQATRKSEKERMREYRRELEEREEKLKNRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKIFEYFSNQEMKNFTEDKESFNEEEKIEERENGEENYLTDTNSQDSCKETDEVNEENGEEKCVEE", "length": 665, "header": "tr|A0AAA9TB97-1|E1BHZ3_BOVIN Computationally mapped isoform of Protein FAM161A OS=Bos taurus OX=9913 GN=FAM161A PE=3 SV=1 CANONICAL=E1BHZ3-1" }, "locus": { "chromosome": "11", "start_pos": 60449603, "end_pos": 60421301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092987.1", "url": "https://www.ensembl.org/id/ENSBTAT00000092987.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095254.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095254.1" } ] } }, { "isoform_ac": "E1BHZ3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3/entry#E1BHZ3-1", "sequence": { "sequence": "MAASHRAAKLAASSLQTPVNPNTRARVAQYERKDPLNSLSAAAAAMEEEEEEEEKEAAARLARAPADFNTSISRVNEQKHISHEDFVNFSDIYHSNEEYFRKLEELKAAHIETMAKLEKLYQSKLNLKEVQPAVTREEAASVSSGSLSEKNSYHPVSLMTSISEPDLSQSSSLIVSSSEEELPNLEKKYSEKSGMMTYAKELINNMWTNFSVEDYIQHEDVNLPVLEKQRKKPKEWVPRITVPEPFQMMVREQKKKEENMKSKSDIEMVHKLLKKQEEESECKKKFRANPVPAFVFLPLYHDIVKQNEVRRRAMKERNKEALLASQKPFKFVAREEQKQAVREKQLKDFFKSKKKTNRFKARPVPRSTYSSTINDKLTEEELYKNMRAQQRTQDFLQNPSPRPYSPARRSFATRKSRGPEQAEKSKYKHRVRRQAADSEDLPERYQKHHSEQKYRKFLTVCEPCDLQAASHSATKREKILADIEADEENLKETRWPYLSPRRKSPVRAANTKPAPCSCNPPTPTVSSRGREQATRRSLEEKKMLEEERHRILTKQKQRMKELQKLLTTRAKAYDSHESLAQMSKSRIKALRKSEKERMREYRRELEEREEKLKNRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKIFEYFSNQEMKNFTEDKESFNEEEKIEERENGEENYLTDTNSQDSCKETDEVNEENGEEKCVEE", "length": 721, "header": "tr|E1BHZ3-1|E1BHZ3_BOVIN Isoform 1 of Protein FAM161A OS=Bos taurus OX=9913 GN=FAM161A PE=3 SV=3 CANONICAL=E1BHZ3-1" }, "locus": { "chromosome": "11", "start_pos": 60449603, "end_pos": 60421301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012239.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012239.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012239.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012239.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 524, "start_aa": "Thr", "end_pos": 524, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr524", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:532883", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532883", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" }, { "name": "astral microtubule", "id": "GO:0000235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000235", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ3", "url": "https://www.uniprot.org/uniprotkb/E1BHZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHZ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 721, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHZ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHZ3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], 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{ "uniprot_canonical_ac": "E1BKQ9-1", "uniprot_ac": "E1BKQ9", "uniprot_id": "E1BKQ9_BOVIN", "mass": { "chemical_mass": 106750.0, "monoisotopic_mass": 106750.0 }, "refseq": { "ac": "NP_001137331", "name": "polypeptide N-acetylgalactosaminyltransferase 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137331" }, "gene_names": [ { "name": "GALNT5", "type": "recommended", "evidence": [ { "id": "E1BKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ] }, { "name": "GALNT5", "type": "synonym", "evidence": [ { "id": "NP_001137331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137331" } ] } ], "protein_names": [ { "name": "Polypeptide N-acetylgalactosaminyltransferase", "type": "recommended", "evidence": [ { "id": "E1BKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "E1BKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9/entry#names_and_taxonomy" } ] }, { "name": "Protein-UDP acetylgalactosaminyltransferase", "type": "synonym", "evidence": [ { "id": "E1BKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9/entry#names_and_taxonomy" } ] }, { "name": "UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)", "type": "synonym", "evidence": [ { "id": "NP_001137331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137331" } ] }, { "name": "polypeptide N-acetylgalactosaminyltransferase 5", "type": "synonym", "evidence": [ { "id": "NP_001137331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137331" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKQ9", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GALNT5", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9", "locus": { "chromosome": "2", "start_pos": 39026684, "end_pos": 39069321, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017376", "url": "https://www.ensembl.org/id/ENSBTAG00000017376" } ] } } ], "crossref": [ { "id": "E1BKQ9", "url": "https://alphafold.ebi.ac.uk/entry/E1BKQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017376", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017376", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02510", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02510", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "504711", "url": "https://www.ncbi.nlm.nih.gov/gene/504711", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504711", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504711", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGMHHVL", "url": "https://omabrowser.org/oma/group/HGMHHVL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKQ9", "url": "https://www.orthodb.org/?gene=E1BKQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001137331", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137331", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TM51", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TM51-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKQ9", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKQ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNKIRKFFRGSGRVLAFIFAASVIWLLFDMAALRLSFSEINTQILKEDIVRRERVGFRVQSDQVKSLDSSRTEMKPPWKGHGKGVWGKENFRKTEESKLKVEDDLDQTQKERKVQNAPGRGKVAPLWHPAYRQTHPVTFTKWKTEGRDIRPAVSSHPMTPKQMTAQGLEKTPFIAARGTPLAKISVHTGPVGINKQGPKSHGLNSDISKQAAERYPTVTTSLSNDRLKQRYQAGVNERNYPASPPVPRPREAIALNKTETPSKELNANRHKANKNLTFSKFIANSDRLKKPSINEIQWGGLLKDDRAKVAGGKKLNLSESHVVIITKEEELKTDTREVPNSNTKTTSTIVLGKSQEKRIGMKNNEASFSSLALQRAAVSQANQALTEGQELGKINLTAKTRPAQLNQSQTKALSPEDGRMHRVLRIDATLSPRDPKAPGQFGRPVVVPHGKEKEVERRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNNLPTTSIIMCFVDEVWSTLLRSVHSVLNRSPPHLIKEILLVDDFSTKDYLKDNLDKYMSQFPKVRILRLKERHGLIRARLAGAQKATGDVLTFLDSHVECNIGWLEPLLERVYLSRKKVACPVIEVINDKDMSYMTVDNFQRGIFVWPMNFGWRTIPPDVVAKNKIKETDIIRCPVMAGGLFSIDKNYFFELGTYDPGLDVWGGENMELSFKVWMCGGEIEIVPCSRVGHIFRNDNPYSFPKDRMKTVERNLGRVAEVWLDEYKELFYGHGNHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLENVFPDLKAPIVRASGVLINVALGKCISIRNTTAILEDCDGSSQLQQFNYTWLRLIKHGAWCLAPVPDNGALRLHLCDNRNKGLRWLHKSTSVFRPELVNHLVFGNYHQLLCLEGDFTQKTLKVAPCDPAKPDQKWKFENYYED", "length": 940, "header": "tr|E1BKQ9-1|E1BKQ9_BOVIN Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Bos taurus OX=9913 GN=GALNT5 PE=3 SV=2 CANONICAL=E1BKQ9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TM51-1", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9/entry#A0AAA9TM51-1", "sequence": { "sequence": "MNKIRKFFRGSGRVLAFIFAASVIWLLFDMAALRLSFSEINTQILKEDIVRRERVGFRVQSDQVKSLDSSRTEMKPPWKGHGKGVWGKENFRKTEESKLKVEDDLDQTQKERKVQNAPGRGKVAPLWHPAYRQTHPVTFTKWKTEGRDIRPAVSSHPMTPKQMTAQGLEKTPFIAARGTPLAKISVHTGPVGINKQGPKSHGLNSDISKQAAERYPTVTTSLSNDRLKQRYQAGVNERNYPASPPVPRPREAIALNKTETPSKELNANRHKANKNLTFSKFIANSDRLKKPSINEIQWGGLLKDDRAKVAGGKKLNLSESHVVIITKEEELKTDTREVPNSNTKTTSTIVLGKSQEKRIGMKNNEASFSSLALQRAAVSQANQALTEGQELGKINLTAKTRPAQLNQSQTKALSPEDGRMHRVLRIDATLSPRDPKAPGQFGRPVVVPHGKEKEVERRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNNLPTTSIIMCFVDEVWSTLLRSVHSVLNRSPPHLIKEILLVDDFSTKDYLKDNLDKYMSQFPKVRILRLKERHGLIRARLAGAQKATGDVLTFLDSHVECNIGWLEPLLERVYLSRKKVACPVIEVINDKDMRCPVMAGGLFSIDKNYFFELGTYDPGLDVWGGENMELSFKVWMCGGEIEIVPCSRVGHIFRNDNPYSFPKDRMKTVERNLGRVAEVWLDEYKELFYGHGNHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLENVFPDLKAPIVRASGVLINVALGKCISIRNTTAILEDCDGSSQLQQFNYTWLRLIKHGAWCLAPVPDNGALRLHLCDNRNKGLRWLHKSTSVFRPELVNHLVFGNYHQLLCLEGDFTQKTLKVAPCDPAKPDQKWKFENYYED", "length": 900, "header": "tr|A0AAA9TM51-1|E1BKQ9_BOVIN Computationally mapped isoform of Polypeptide N-acetylgalactosaminyltransferase OS=Bos taurus OX=9913 GN=GALNT5 PE=3 SV=1 CANONICAL=E1BKQ9-1" }, "locus": { "chromosome": "2", "start_pos": 39069122, "end_pos": 39027688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130736.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130736.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098326.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098326.1" } ] } }, { "isoform_ac": "E1BKQ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9/entry#E1BKQ9-1", "sequence": { "sequence": "MNKIRKFFRGSGRVLAFIFAASVIWLLFDMAALRLSFSEINTQILKEDIVRRERVGFRVQSDQVKSLDSSRTEMKPPWKGHGKGVWGKENFRKTEESKLKVEDDLDQTQKERKVQNAPGRGKVAPLWHPAYRQTHPVTFTKWKTEGRDIRPAVSSHPMTPKQMTAQGLEKTPFIAARGTPLAKISVHTGPVGINKQGPKSHGLNSDISKQAAERYPTVTTSLSNDRLKQRYQAGVNERNYPASPPVPRPREAIALNKTETPSKELNANRHKANKNLTFSKFIANSDRLKKPSINEIQWGGLLKDDRAKVAGGKKLNLSESHVVIITKEEELKTDTREVPNSNTKTTSTIVLGKSQEKRIGMKNNEASFSSLALQRAAVSQANQALTEGQELGKINLTAKTRPAQLNQSQTKALSPEDGRMHRVLRIDATLSPRDPKAPGQFGRPVVVPHGKEKEVERRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNNLPTTSIIMCFVDEVWSTLLRSVHSVLNRSPPHLIKEILLVDDFSTKDYLKDNLDKYMSQFPKVRILRLKERHGLIRARLAGAQKATGDVLTFLDSHVECNIGWLEPLLERVYLSRKKVACPVIEVINDKDMSYMTVDNFQRGIFVWPMNFGWRTIPPDVVAKNKIKETDIIRCPVMAGGLFSIDKNYFFELGTYDPGLDVWGGENMELSFKVWMCGGEIEIVPCSRVGHIFRNDNPYSFPKDRMKTVERNLGRVAEVWLDEYKELFYGHGNHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLENVFPDLKAPIVRASGVLINVALGKCISIRNTTAILEDCDGSSQLQQFNYTWLRLIKHGAWCLAPVPDNGALRLHLCDNRNKGLRWLHKSTSVFRPELVNHLVFGNYHQLLCLEGDFTQKTLKVAPCDPAKPDQKWKFENYYED", "length": 940, "header": "tr|E1BKQ9-1|E1BKQ9_BOVIN Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Bos taurus OX=9913 GN=GALNT5 PE=3 SV=2 CANONICAL=E1BKQ9-1" }, "locus": { "chromosome": "2", "start_pos": 39069122, "end_pos": 39027688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023104.5", "url": "https://www.ensembl.org/id/ENSBTAT00000023104.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023104.3", "url": "https://www.ensembl.org/id/ENSBTAP00000023104.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:504711", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504711", "resource": "KEGG Pathway" }, { "id": "R-BTA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LCH7-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "GALNT5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNKIRKFFRGSGRVLAFIFVASVIWLLFDMAALRLSFSEINSRVLKEDIVRRERIGFRVQPDQVKILYSSVKDMKPPLKGHRKGIWGKENFRKTEESKLKVEDNLDQTQKERKMQNAPGRGKVAPLWRPAYLQTLPVTFIKRKTEARDISPKASSHHVTPKQTTAQGAQKVPLITTRRIPLAKISIHQGPVSINQEARKNHSLSSDTSKQTAERNMNATISLNIDRSKQQSQAVANERTHPASPPVPKPREAIALNKTETQSKELSANKHKANKNFPFSKFFANSNLLKKQSINETQLRGLPKDGGAKVADGRKLHLPESHIVIITKEEELKTETKEVPKTKTKTLFPIGPAESQGKHIAKNRSEASFSSLAPQRAIVSQTSQALPGGLEPSRINSTTKAEPTQLNRSHITAHSPKDGGMHRVLSIDLTLSPRDPKAPGQFGRPVVVPQGKEKEVEKRWKEGNFNVYLSDLIPVDRAIEDTRPAGCADQLVHNKLPTTSVIMCFVDEVWSTLLRSVHSVLNRSPPHLIKEILLVDDFSTKDYLKDNLDKYMSQFPKVRILRLKERHGLIRARLAGAQIATGDVLTFLDSHVECNVGWLEPLLERVYLSRKKVACPVIEVINDKDMSYMTVDNFQRGIFVWPMNFGWRTIPPDIVAKNKIKETDIIRCPVMAGGLFSIDKTYFFELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDEYKELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLENVFPDLKAPIVRASGVLINVALGKCISIKNTTAILEDCDGSSKLQQFNYTWLRLIKQGEWCLAPVPDNGALTLHPCDNRNKGLKWLHKSTSVFHPELVNHIVFGNYHQLLCLEGNMSLKTLKVAACDPVKPYQKWKFEKYYED", "length": 940 }, "evidence": [ { "id": "E1BKQ9", "url": "https://omabrowser.org/oma/group/E1BKQ9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O88422-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 5", "gene_name": "Galnt5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNKIRKFFRGSGRVLAFIFVASVIWLLFDMAALRLSFSEINTGILKEDIMRREQTGFRVEADQMTILSPSSRGMRPPRNGAGGKESFRKAENRVLKVEENVDQVQRKGKMQFLLGRGKAVSLWHRTHVQTLPVTLPMQKTQGRDSKPEVSSLHMMSKQTTVLGSEKDSFTVSRGVPLNKTAEHTETLDKKQEAPENYNLSSDTSKQASQRALNVTISVRTDRSKQQSQTVTKSSIQFASLPILKPEEVTVTKKTEAQGKDLKYEAHKARPLLKFTADVGHLKKQSTNETGLGVLPEADGAKVAPGKKLNFSESQIVIITKEEGQKTDTKEVPNSKIQTVFPKLLGESQGKHIPRSQSQTLSSPLAPKRAVSQSKPTLAEELHTARSNLTAKATTVGHQQSHANISENPGKHHVLRIDVTLSPRDLNAPGQFGRPVVVPPGKKKEAEQRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNDLPTTSIIMCFVDEVWSALLRSVHSVLNRSPPHLIKEILLVDDFSTKDYLKANLDKYMSQFPKVRILRLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLNRKKVACPVIEVINDKDMSYMTVDNFQRGVFTWPMNFGWRTIPPDVIAKNGIKETDIIRCPVMAGGLFSIDKSYFYELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDEYKELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCQSFKWYLDNVFPDLKAPVVRASGVFINLALGKCVSIKNITVVLEDCDGSSELQQFNYTWVRLIKHGEWCVAPIPDKGSLTLYPCDNRNNRLKWLHRSASAFHPELVDHIVFESYQQLLCMEGNFSQKTLKLAACNPTEPQQKWKFEKYYDV", "length": 930 }, "evidence": [ { "id": "E1BKQ9", "url": "https://omabrowser.org/oma/group/E1BKQ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z7M9-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 5", "gene_name": "GALNT5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRIRKFFRGSGRVLAFIFVASVIWLLFDMAALRLSFSEINTRVIKEDIVRRERIGFRVQPDQGKIFYSSIKEMKPPLRGHGKGAWGKENVRKTEESVLKVEVDLDQTQRERKMQNALGRGKVVPLWHPAHLQTLPVTPNKQKTDGRGTKPEASSHQGTPKQTTAQGAPKTSFIAAKGTQVVKISVHMGRVSLKQEPRKSHSPSSDTSKLAAERDLNVTISLSTDRPKQRSQAVANERAHPASTAVPKSGEAMALNKTKTQSKEVNANKHKANTSLPFPKFTVNSNRLRKQSINETPLGSLSKDDGARGAHGKKLNFSESHLVIITKEEEQKADPKEVSNSKTKTIFPKVLGKSQSKHISRNRSEMSSSSLAPHRVPLSQTNHALTGGLEPAKINITAKAPSTEYNQSHIKALLPEDSGTHQVLRIDVTLSPRDPKAPGQFGRPVVVPHGKEKEAERRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNNLPTTSVIMCFVDEVWSTLLRSVHSVINRSPPHLIKEILLVDDFSTKDYLKDNLDKYMSQFPKVRILRLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLSRKKVACPVIEVINDKDMSYMTVDNFQRGIFVWPMNFGWRTIPPDVIAKNRIKETDTIRCPVMAGGLFSIDKSYFFELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDEYKELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLENVFPDLRAPIVRASGVLINVALGKCISIENTTVILEDCDGSKELQQFNYTWLRLIKCGEWCIAPIPDKGAVRLHPCDNRNKGLKWLHKSTSVFHPELVNHIVFENNQQLLCLEGNFSQKILKVAACDPVKPYQKWKFEKYYEA", "length": 940 }, "evidence": [ { "id": "E1BKQ9", "url": "https://omabrowser.org/oma/group/E1BKQ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C102-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 5", "gene_name": "Galnt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNKIRKFFRGSGRVLAFIFAASVIWLLFDMAALRLSFSEINAGLLKEDIIRREHTGFRVEPDQVKVLYTSIRGMGLPRNGAWGKENFRKAENHELKVEENMDQVQRKGKMQNLLGRRKAVPLWHLAHLQTLPVTIPMQKTQGRDSKPEVSSQYMMSKWMTVLESEKTPFTASRGVPLTKIAGRTETFDKKQEAPQNYNVSSDTSKQASERTLNMTISVKTDRSKQKSQTVTKLRMHFASPPILKSEEVTVIKKAEAQSKDLKHEALKALPLLKFIADMGHLKNQSTNETQLGRLPEDDAAKVAPGKKLNFSESHVVIITKEEELKTDTKEVPNSKTQTVFPKLLGGSPHKQIPRNQSKTSSSPPALKKAVSQSKPTISGGLHTARSNLTAKAPTVGYQQSHANIPENPGMHHVFRIDVTLSPRDLNAPGQFGRPVVVPPEKKKEAEQRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNDLPTTSIIMCFVDEVWSALLRSVHSVLNRSPPHLIKEILLVDDFSTKEYLKADLDKYMSQFPKVRILRLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLNRKKVACPVIEVINDKDMSYMTVDNFQRGVFTWPMNFGWKTIPPDVVAKNGIKETDIIRCPVMAGGLFSIDKSYFYELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDDYRELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLDNVFPDLKAPVVRASGVLINMALGKCVSIENITVTLEDCDGSSQLQQFNYTWVRLIKHGEWCVAPIPEKGSLTLYHCDNRNNRLKWLHKSASAFHPELVDHIVFENYQQLLCMEGNFSQKTLKLAACNPMELQQKWKFEKYYEV", "length": 930 }, "evidence": [ { "id": "E1BKQ9", "url": "https://omabrowser.org/oma/group/E1BKQ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BKQ9", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BKQ9", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "E1BKQ9", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "E1BKQ9", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BKQ9", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ], "pmid": "" }, { "name": "polypeptide N-acetylgalactosaminyltransferase activity", "id": "GO:0004653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004653", "evidence": [ { "database": "UniProtKB", "id": "E1BKQ9", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "E1BKQ9", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" }, { "start_pos": 845, "end_pos": 847, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-913675", "name": "GALNTs transfer GalNAc to Mucins to form Tn antigens", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-9942384" ], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M986-1", "Q07537-1", "E1BDW8-1", "E1BHN6-1", "A0AAA9T153-1", "F1N554-1", "F6QA59-1", "F6RJ62-1", "A0AAA9S1Y7-1", "E1BPR6-1", "E1B9U7-1", "A0AAA9S5W3-1", "E1BKQ9-1" ], "evidence": [ { "id": "R-BTA-913675", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913675" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9942384", "participant_name": "UDP-GalNAc [Golgi lumen]", "crossref": [ { "id": "67138", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551132", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M986", "gene_name": "GALNT2", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A3Q1M986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M986" } ] } ] }, { "uniprot_ac": "A0AAA9S1Y7", "gene_name": "GALNT14", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0AAA9S1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1Y7" } ] } ] }, { "uniprot_ac": "A0AAA9S5W3", "gene_name": "GALNT3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0AAA9S5W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W3" } ] } ] }, { "uniprot_ac": "A0AAA9T153", "gene_name": "GALNT7", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0AAA9T153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T153" } ] } ] }, { "uniprot_ac": "E1B9U7", "gene_name": "GALNT17", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1B9U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9U7" } ] } ] }, { "uniprot_ac": "E1BDW8", "gene_name": "GALNT11", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BDW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDW8" } ] } ] }, { "uniprot_ac": "E1BHN6", "gene_name": "GALNT15", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BHN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHN6" } ] } ] }, { "uniprot_ac": "E1BKQ9", "gene_name": "GALNT5", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ] } ] }, { "uniprot_ac": "E1BPR6", "gene_name": "GALNT9", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BPR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPR6" } ] } ] }, { "uniprot_ac": "F1N554", "gene_name": "GALNT10", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F1N554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N554" } ] } ] }, { "uniprot_ac": "F6QA59", "gene_name": "GALNT8", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F6QA59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QA59" } ] } ] }, { "uniprot_ac": "F6RJ62", "gene_name": "GALNT18", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F6RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ] } ] }, { "uniprot_ac": "Q07537", "gene_name": "GALNT1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "Q07537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07537" } ] }, { "ec_number": "2.4.1.41", "activity": "L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "Q07537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07537" } ] }, { "ec_number": "2.4.1.41", "activity": "", "evidence": [ { "id": "Q07537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07537" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKQ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 940, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKQ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKQ9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" }, { "id": "SM00458", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00458" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ricin B lectin", "eco_id": "ECO_0000259", "start_pos": 809, "end_pos": 935, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00027JG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00030VN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00031MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00032MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00033MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034UM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00035MO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00036MO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00037MO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00038MO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00039MO", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G00040MO", 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHM3-1", "uniprot_ac": "E1BHM3", "uniprot_id": "E1BHM3_BOVIN", "mass": { "chemical_mass": 22389.0, "monoisotopic_mass": 22389.0 }, "refseq": { "ac": "NP_001179986", "name": "protein lin-28 homolog A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179986" }, "gene_names": [ { "name": "LIN28A", "type": "recommended", "evidence": [ { "id": "E1BHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ] }, { "name": "LIN28A", "type": "synonym", "evidence": [ { "id": "NP_001179986", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179986" } ] }, { "name": "LIN28", "type": "synonym", "evidence": [ { "id": "NP_001179986", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179986" } ] } ], "protein_names": [ { "name": "Protein lin-28 homolog A", "type": "recommended", "evidence": [ { "id": "E1BHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHM3/entry#names_and_taxonomy" } ] }, { "name": "lin-28 homolog A", "type": "synonym", "evidence": [ { "id": "NP_001179986", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179986" } ] }, { "name": "protein lin-28 homolog A", "type": "synonym", "evidence": [ { "id": "NP_001179986", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179986" } ] } ], "function": [ { "annotation": "Lin28 pseudogenes do not acquire patterns of tissue-specific methylation as for the parental gene, but rather are methylated in patterns specific to the local genomic environment into which they were inserted. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001179986", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179986" }, { "database": "PubMed", "id": "25884154", "url": "https://glygen.org/publication/PubMed/25884154" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LIN28A", "url": "https://www.uniprot.org/uniprotkb/E1BHM3", "locus": { "chromosome": "2", "start_pos": 126707948, "end_pos": 126721394, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040497", "url": "https://www.ensembl.org/id/ENSBTAG00000040497" } ] } } ], "crossref": [ { "id": "E1BHM3", "url": "https://alphafold.ebi.ac.uk/entry/E1BHM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000040497", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000040497", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04458", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04458", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614997", "url": "https://www.ncbi.nlm.nih.gov/gene/614997", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614997", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614997", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NEPQPLH", "url": "https://omabrowser.org/oma/group/NEPQPLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHM3", "url": "https://www.orthodb.org/?gene=E1BHM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46109:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46109:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21890", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21890", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179986", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179986", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TWQ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHM3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSVSNQQFAGGCAKAPEEAPEDAARAAEEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKNMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSINHMVASCPLKAQQAPSSQGKPAYFREEEEEIHSSAMLPEAQN", "length": 205, "header": "tr|E1BHM3-1|E1BHM3_BOVIN Isoform 1 of Protein lin-28 homolog A OS=Bos taurus OX=9913 GN=LIN28A PE=3 SV=1 CANONICAL=E1BHM3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TWQ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BHM3/entry#A0AAA9TWQ2-1", "sequence": { "sequence": "MRKNSLHGINWERFERSRETRWETQRHSETDLERPRLGGCAKAPEEAPEDAARAAEEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKNMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSINHMVASCPLKAQQAPSSQGKPAYFREEEEEIHSSAMLPEAQN", "length": 232, "header": "tr|A0AAA9TWQ2-1|E1BHM3_BOVIN Computationally mapped isoform of Protein lin-28 homolog A OS=Bos taurus OX=9913 GN=LIN28A PE=3 SV=1 CANONICAL=E1BHM3-1" }, "locus": { "chromosome": "2", "start_pos": 126721195, "end_pos": 126708952, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093911.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093911.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101024.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101024.1" } ] } }, { "isoform_ac": "E1BHM3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHM3/entry#E1BHM3-1", "sequence": { "sequence": "MGSVSNQQFAGGCAKAPEEAPEDAARAAEEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKNMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSINHMVASCPLKAQQAPSSQGKPAYFREEEEEIHSSAMLPEAQN", "length": 205, "header": "tr|E1BHM3-1|E1BHM3_BOVIN Isoform 1 of Protein lin-28 homolog A OS=Bos taurus OX=9913 GN=LIN28A PE=3 SV=1 CANONICAL=E1BHM3-1" }, "locus": { "chromosome": "2", "start_pos": 126720207, "end_pos": 126708950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004196.4", "url": "https://www.ensembl.org/id/ENSBTAT00000004196.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004196.2", "url": "https://www.ensembl.org/id/ENSBTAP00000004196.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "DNA methylation of the LIN28 pseudogene family.", "journal": "BMC genomics", "date": "2015-04-11", "authors": "Davis Aaron P, Benninghoff Abby D, Thomas Aaron J, Sessions Benjamin R, White Kenneth L", "evidence": [ { "database": "RefSeq", "id": "NP_001179986", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179986" } ], "reference": [ { "type": "PubMed", "id": "25884154", "url": "https://glygen.org/publication/PubMed/25884154" } ] } ], "pathway": [ { "id": "bta:614997", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614997", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q45KJ5-1", "protein_name": "Protein lin-28 homolog A", "gene_name": "LIN28A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGSVSNQQFAGAKPGEEPSGDSPKAENESQPLHGSGICKWFNVRMGFGFLSMTAKGGAMLDSPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSSKGLESIRVTGPGGVFCIGSERRPKSKSLQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVANCPAKAQQSPSSQGKPAYFREKEDMHSSALLPETRE", "length": 202 }, "evidence": [ { "id": "E1BHM3", "url": "https://omabrowser.org/oma/group/E1BHM3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8K3Y3-1", "protein_name": "Protein lin-28 homolog A", "gene_name": "Lin28a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSVSNQQFAGGCAKAAEKAPEEAPPDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKNMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSINHMVASCPLKAQQGPSSQGKPAYFREEEEEIHSPALLPEAQN", "length": 209 }, "evidence": [ { "id": "E1BHM3", "url": "https://omabrowser.org/oma/group/E1BHM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H9Z2-1", "protein_name": "Protein lin-28 homolog A", "gene_name": "LIN28A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQGPSAQGKPTYFREEEEEIHSPTLLPEAQN", "length": 209 }, "evidence": [ { "id": "E1BHM3", "url": "https://omabrowser.org/oma/group/E1BHM3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of miRNA-mediated gene silencing", "id": "GO:0060964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060964", "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "pmid": "" }, { "name": "post-transcriptional regulation of gene expression", "id": "GO:0010608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "database": "UniProtKB", "id": "E1BHM3", "url": "https://www.uniprot.org/uniprotkb/E1BHM3" } ], "pmid": "" }, { "name": "pre-miRNA processing", "id": "GO:0031054", "url": 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CANONICAL=E1BJD3-1" }, "locus": { "chromosome": "18", "start_pos": 62109590, "end_pos": 62106933, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117670.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117670.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086907.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086907.1" } ] } }, { "isoform_ac": "A0AAA9TM09-1", "url": "https://www.uniprot.org/uniprotkb/E1BJD3/entry#A0AAA9TM09-1", "sequence": { "sequence": "MPPHSDSGSGHSKGNEPHPHWLEAERRFRGELRISSQPSPQVGLLPYHWGTRPEAWGPQLEAPEGWGGNMVGSGIPALGLLLLMQGSADGNGIQGFFYPWSCEGDVWDRESCGGQAAIENPNLCLRLRCCYRDGVCYHQRPDENMRRKHMWALGWTCGGLLFLITSICLFWWARRHDMLRLPWFLKGKCDLSRTVSLLSKLRAKKTPSVGSIPPAAPTEGALDVSGGTEGEGTEGGEETEGGDEDD", "length": 246, "header": "tr|A0AAA9TM09-1|TM190_BOVIN Computationally mapped isoform of Transmembrane protein 190 OS=Bos taurus OX=9913 GN=TMEM190 PE=3 SV=1 CANONICAL=E1BJD3-1" }, "locus": { "chromosome": "18", "start_pos": 62109590, "end_pos": 62107594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104795.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104795.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098282.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098282.1" } ] } }, { "isoform_ac": "A0AAF6Z941-1", "url": "https://www.uniprot.org/uniprotkb/E1BJD3/entry#A0AAF6Z941-1", "sequence": { "sequence": "MSPILTGWKLSAGSGENSGSVPNPVPRSLPTEAPEGWGGNMVGSGIPALGLLLLMQGSADGNGIQGFFYPWSCEGDVWDRESCGGQAAIENPNLCLRLRCCYRDGVCYHQRPDENMRRKHMWALGWTCGGLLFLITSICLFWWARRHDMLRLPWFLKGKCDLSRTVSLLSKDRTPSEKKTPSVGSIPPAAPTEGALDVSGGTEGEGTEGGEETEGGDEDD", "length": 220, "header": "tr|A0AAF6Z941-1|TM190_BOVIN Computationally mapped isoform of Transmembrane protein 190 OS=Bos taurus OX=9913 GN=TMEM190 PE=3 SV=1 CANONICAL=E1BJD3-1" }, "locus": { "chromosome": "18", "start_pos": 62109547, "end_pos": 62107594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIQ6-1", "uniprot_ac": "E1BIQ6", "uniprot_id": "E1BIQ6_BOVIN", "mass": { "chemical_mass": 92429.0, "monoisotopic_mass": 92429.0 }, "refseq": { "ac": "XP_059745859", "name": "transcription regulator protein BACH2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745859" }, "gene_names": [ { "name": "BACH2", "type": "recommended", "evidence": [ { "id": "E1BIQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6" } ] }, { "name": "BACH2", "type": "synonym", "evidence": [ { "id": "XP_059745859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745859" } ] } ], "protein_names": [ { "name": "BTB domain and CNC homolog 2", "type": "synonym", "evidence": [ { "id": "E1BIQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6/entry#names_and_taxonomy" } ] }, { "name": "transcription regulator protein BACH2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059745859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745859" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIQ6", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BACH2", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6", "locus": { "chromosome": "9", "start_pos": 60342241, "end_pos": 59950876, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020713", "url": "https://www.ensembl.org/id/ENSBTAG00000020713" } ] } } ], "crossref": [ { "id": "E1BIQ6", "url": "https://alphafold.ebi.ac.uk/entry/E1BIQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020713", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020713", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14719", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14719", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18278", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18278", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538296", "url": "https://www.ncbi.nlm.nih.gov/gene/538296", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538296", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538296", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MMGDGMY", "url": "https://omabrowser.org/oma/group/MMGDGMY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03131", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03131", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059745859", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745859", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGL2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIQ6", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIQ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVDEKPDSPMYVYESTVHCANILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKNDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMHNLEDSCFSFLQTQLLNSEDGLFVCRKDAACQRPHEDPEDSAGEEEDEEEETMDSDTAKMACPRDQMLPDPISFEATTIPVAEKEEVLLPESDVPADTKESSAKDALTQYPRYKKYQLACTKNVYNASSHSTSGFASTFSEDHSGTSLKPGLAVGQIKSEPPSEENEEESITLCLSGDEPDVKDRAGDVEMDRKQPSPAPAPVPAPPAGAACLERSRGAPSPSCLRSLFSITKSVESSGLPGTSQQHFARSSACPFDKGITQGDLKTDYAPFPGNYGQPHMGQKDTSSFTMGSPLKGPGLEALCKQEGELDRRSVIFSSSACDQVSTAVHSYSGVSALDKDLSEPVPKGLWVGAGQSLPSSQAYPHGGLMADHLPGRMRPNTSCPVPIKVCPRSPPLETRTRTSSSCSSYSYAEDGSGGSPCSLPLCEFSSSPCSQGARFLATEHQEPGLMGDGMYNQVRPQIKCEQSYGTNSSDESGSFSEADSESCPVQDRGQEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDVRRRSKNRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNQLKACMGELLDNFSCLSQEVCRDIQSPEQIQALHRYCPVLRPVGLPTAPSINPTPLSVEQNLATPQCAVGESAPCCLEQGAAAPGPPWAPSNASENCTSARRLEGTDPGTFSERGPPLEPRSQTVTVDFCQEMTDKCTTDEQPRKDYTQ", "length": 844, "header": "tr|E1BIQ6-1|E1BIQ6_BOVIN Isoform 1 of BTB domain and CNC homolog 2 OS=Bos taurus OX=9913 GN=BACH2 PE=3 SV=2 CANONICAL=E1BIQ6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MGL2-1", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6/entry#A0A3Q1MGL2-1", "sequence": { "sequence": "MNKGVNGMSVDEKPDSPMYVYESTVHCANILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKNDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMHNLEDSCFSFLQTQLLNSEDGLFVCRKDAACQRPHEDPEDSAGEEEDEEEETMDSDTAKMACPRDQMLPDPISFEATTIPVAEKEEVLLPESDVPADTKESSAKDALTQYPRYKKYQLACTKNVYNASSHSTSGFASTFSEDHSGTSLKPGLAVGQIKSEPPSEENEEESITLCLSGDEPDVKDRAGDVEMDRKQPSPAPAPVPAPPAGAACLERSRGAPSPSCLRSLFSITKSVESSGLPGTSQQHFARSSACPFDKGITQGDLKTDYAPFPGNYGQPHMGQKDTSSFTMGSPLKGPGLEALCKQEGELDRRSVIFSSSACDQVSTAVHSYSGVSALDKDLSEPVPKGLWVGAGQSLPSSQAYPHGGLMADHLPGRMRPNTSCPVPIKVCPRSPPLETRTRTSSSCSSYSYAEDGSGGSPCSLPLCEFSSSPCSQGARFLATEHQEPGLMGDGMYNQVRPQIKCEQSYGTNSSDESGSFSEADSESCPVQDRGQEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDVRRRSKNRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNQLKACMGELLDNFSCLSQEVCRDIQSPEQIQALHRYCPVLRPVGLPTAPSINPTPLSVEQNLATPQCAVGESAPCCLEQGAAAPGPPWAPSNASENCTSARRLEGTDPGTFSERGPPLEPRSQTVTVDFCQEMTDKCTTDEQPRKDYTQ", "length": 851, "header": "tr|A0A3Q1MGL2-1|E1BIQ6_BOVIN Computationally mapped isoform of BTB domain and CNC homolog 2 OS=Bos taurus OX=9913 GN=BACH2 PE=3 SV=1 CANONICAL=E1BIQ6-1" }, "locus": { "chromosome": "9", "start_pos": 60341237, "end_pos": 60047433, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068721.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068721.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070325.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070325.2" } ] } }, { "isoform_ac": "E1BIQ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6/entry#E1BIQ6-1", "sequence": { "sequence": "MSVDEKPDSPMYVYESTVHCANILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKNDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMHNLEDSCFSFLQTQLLNSEDGLFVCRKDAACQRPHEDPEDSAGEEEDEEEETMDSDTAKMACPRDQMLPDPISFEATTIPVAEKEEVLLPESDVPADTKESSAKDALTQYPRYKKYQLACTKNVYNASSHSTSGFASTFSEDHSGTSLKPGLAVGQIKSEPPSEENEEESITLCLSGDEPDVKDRAGDVEMDRKQPSPAPAPVPAPPAGAACLERSRGAPSPSCLRSLFSITKSVESSGLPGTSQQHFARSSACPFDKGITQGDLKTDYAPFPGNYGQPHMGQKDTSSFTMGSPLKGPGLEALCKQEGELDRRSVIFSSSACDQVSTAVHSYSGVSALDKDLSEPVPKGLWVGAGQSLPSSQAYPHGGLMADHLPGRMRPNTSCPVPIKVCPRSPPLETRTRTSSSCSSYSYAEDGSGGSPCSLPLCEFSSSPCSQGARFLATEHQEPGLMGDGMYNQVRPQIKCEQSYGTNSSDESGSFSEADSESCPVQDRGQEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDVRRRSKNRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNQLKACMGELLDNFSCLSQEVCRDIQSPEQIQALHRYCPVLRPVGLPTAPSINPTPLSVEQNLATPQCAVGESAPCCLEQGAAAPGPPWAPSNASENCTSARRLEGTDPGTFSERGPPLEPRSQTVTVDFCQEMTDKCTTDEQPRKDYTQ", "length": 844, "header": "tr|E1BIQ6-1|E1BIQ6_BOVIN Isoform 1 of BTB domain and CNC homolog 2 OS=Bos taurus OX=9913 GN=BACH2 PE=3 SV=2 CANONICAL=E1BIQ6-1" }, "locus": { "chromosome": "9", "start_pos": 60341237, "end_pos": 60255450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027603.5", "url": "https://www.ensembl.org/id/ENSBTAT00000027603.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027603.4", "url": "https://www.ensembl.org/id/ENSBTAP00000027603.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538296", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538296", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2UDQ5-1", "protein_name": "BTB domain and CNC homolog 2", "gene_name": "BACH2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSVPEYSWTSRESCHSGAVEPEGVNGMSVDEKTDSPMYVYESTVHCTNILLCLNDQRKQDILCDVTLIVEGKEFRAHRAVLAACSEYFLQALVGQTENDLVVSLPEEVTVRGFGPLLQFAYTAKLLLSRENIQEVIHCAEFLRMHNLEDSCFSFLQTQLLNNEDGLFLCKKDTTCQRMHDEENSDGDEEETMESETSKISCPRERMHQEPFNFETAVAGADKGEGILPNSDMLRDSKDNLDKDAVTRYPRYKKYQLACTKNVYNTSHISTSGFASTFSEESSGNGLKSGLAMGQIKSEPQNEENDEESITLCLSGDEPDIRDKEGDVEMDRKQPSPTCVDRPKSGSSPSCLRSFFNRTKSIDLVGFPSTSQQHFGRSPACPFEKGTTQGDHKTDYVPFTGNYGQSHAMQKDASNFTVGSPLRGPGFETLCKQEGELDRRSVIFSSNACDQVNTSVHSYSGVSSLDKDLTETVPKGLWAGGSQSLPSSQTYSHSGLTADHLSGRMRPNTSCPVPIKVCPRSPPLETRTRTSSSCSSYSYAEDGSGGSPCSLRLCELSSSPCSQGPRFLAPEHQEPGVVGDGLYNPVRAQIKCEPSYGTNSSDESGSFSEADSESCPVQDRGHEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDVRRRSKNRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNQLKASMGELLDNFSCLSQEVCRDMQSPEQIQALHRYCPVLRPMDLQTATNISPPTGVEQGLATSQCVGEGMQCCSEQGPVQLGASWLPNNVSENCSASGGGLDGAEPGTYPERELPREQSSQTVTVDFCQEMTDKCTTDEQPRKDYT", "length": 850 }, "evidence": [ { "id": "E1BIQ6", "url": "https://omabrowser.org/oma/group/E1BIQ6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZW33-1", "protein_name": "BTB domain and CNC homolog 2", "gene_name": "Bach2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVDEKPDSPMYVYESTVHCANILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKDDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMHNLEDSCFSFLQTQLLNREDGLFVCRKDSACQRPQEDHGNSAGEEEEEEETMDSETARMACATDQMLPDPISFEATAIPVAEKEEALLPESEVPTDTKENSEKGALTQYPRYKKYQLACTKNVYSAASHGTSGFAGTFSEESPGNSLKPGLSVGQIKSEPPNEETEEESITLCLSGDETDIKDRPGDVEMDRKQPSPAPPPGTPTGATSLDRSRSVSSPSCLRSLFSIAKGVESTGLPSTSQQHFVRSSACPFNKGISQGDLKTDYTPLAGNYGQPHVGQKDVSNFAMGSPLRGPGPETLCKQEGELDRRSVIFSASTCDQPNTPVHSYSSVSSLDKDLSEPVPKSLWVGAGQSLPSSQAYSHGGLMADHLPGRIRPNTSCPVPIKVCPRSPPLETRTRTSSSCSSYSYAEDGSGGSPCSLPLCEFSSSPCSQGARFLATEHQEPGLMGDGMYNQVRPQIKCEQSYGTNSSDESGSFSEADSESCPVQDRGQEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDIRRRSKNRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNQLKVCMGELLDNFSCLSQEVCRDIQSPEQIQALHRYCPVLIPMDLPGASVNPPPLGVEQSLAPSQCAVGGSVPCCLEPGAAPPGLPWVPSNTSENCTSGRRLEGSDPGTFSERGPPLEARSQSVTVDFCQEMTEKCTTDEQPRKDYA", "length": 839 }, "evidence": [ { "id": "E1BIQ6", "url": "https://omabrowser.org/oma/group/E1BIQ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RY18-1", "protein_name": "BTB domain and CNC homolog 2", "gene_name": "BACH2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVDEKPDSPMYVYESTVHCTNILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKHDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVLRCAELLRMHNLEDSCFSFLQTQLLNSEDGLFVCRKDAACQRAHEDRENSAGEEEEEEEETMDSETAKMACPRDQMLPDPISFEATAIPVAEKEEVLLPESDVPTDTKESSAKDSLTQYPRYKKYQLACTKNVYNASSHSTSGFASTFGEDNSGNSLKPGLAMGQIKSEPPSEENEEESITLCLSGDEPDIKDRAGDVEMDRKQPSPAPAPAPAPAPAAGAACLERSRGASSPSCLRSLFIAKSVELSGPPGTSQQHFARSSACPFDKGITQGDLKTDYAPFTGNYGQPHMGQKDASSFAMGSPLKGPGLEALCKQEGELDRRSVIFSSSACDQVSTAVHSYSGVSALDKDLSEPVPKGLWVGAGQSLPTSQTYSHGGLMADHLPGRMRPNTSCPVPIKVCPRSPPLETRTRTSSSCSSYSYAEDGSGGSPCSLPLCEFSSSPCSQGARFLATEHQEPGLMGDGMYNQVRPQIKCEQSYGTNSSDESGSFSEADSESCPVQDRGQEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDVRRRSKNRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNQLKACMGELLDNFSCLSQEVCRDIQSPEQIQALHRYCPVLRPVGLPAASSINPTPLGVEQNLATPQCAVGESAPCCLEQGTAPPGPPWAAGNVSENCTARRLEGTDPGTFSERGPPLEPRSQTVTVDFCQEMTDKCTTDEQPRKDYT", "length": 843 }, "evidence": [ { "id": "E1BIQ6", "url": "https://omabrowser.org/oma/group/E1BIQ6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97303-1", "protein_name": "Transcription regulator protein BACH2", "gene_name": "Bach2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVDEKPGSPMYVYESTVHCANILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKDDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMHNLEDSCFSFLQTQLLNREDGLFVCRKDSACQRPQEDHGNSAGEEEEEEETMDSETARMACATDQMLPDPISFEATAIPVAEKEEALLPESEVPTDTKENSEKGALTQYPRYKKYQLACTKNVYSAPSHGTSGFASTFSEDSPGNSLKPGLPMGQIKSEPPSEETEEESITLCLSGDETDIKDRPGDVEMDRKQPSPAPTPSTPTGAACLDRSRSVSSPSCLRSLFGITKGVESTGLPSTSQQPLVRSSACPFNKGISQGDLKTDYTPLAGNYGQPHVGQKDVSNFAMGSPLRGPGPETLCKQEGELDRRSVIFSASACDQPNTPVHSYSAVSNLDKDLSEPVPKSLWVGAGQSLPSSQAYSHSGLMADHLPGRIRPNTSCPVPIKVCPRSPPLETRTRTSSSCSSYSYAEDGSGGSPCSLPLCEFSSSPCSQGARFLATEHQEPGLMGDGMYNQVRPQIKCEQSYGTNSSDESGSFSEADSESCPVQDRGQEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDIRRRSKNRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNHLKACMGELLDNFSCLSQEVCRDIQSPEQIQALHRYCPVLIPMDLPGASVNPPPVGVEQSLAPSPCAVGGSVPCCLEPGAAPPGLPWVPSNTSENCTSGRRLEGSDPGTFSERGPPLEARSQSVTVDFCQEMTEKCTTDEQPRKDYA", "length": 839 }, "evidence": [ { "id": "E1BIQ6", "url": "https://omabrowser.org/oma/group/E1BIQ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RIW6-1", "protein_name": "Transcription regulator protein BACH2 isoform X1", "gene_name": "bach2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLTLGAVIATSCQSSQTMEQTTGVSGMSVDEKSEAPMYVYESTVHCTNILLGLNEQRKQGLLCDVTVLVEGKEFRAHRAVLAACSEYFLQGFATQTDNDLVLSMPEEVSARGFAPLLQFAYTAKLLLSRENIQEVIRCAEFLRMHNLEDSCFRFLEAQLRSEEDGLLLCRKMASESNHSEDEGMQPELLTTTAVTLPGSPRSRLCAEALHSLRRPDHEQLAGTEDFTDGPMDFERHGTSDLPRCPKYRKYQLACNKHNNDASSHTSTSGFPSTFKEMSRPAVMQIKQEPRSEEESISLCLSGNEQEDGEKDDVAEMDLDGSITVDQPKGRSKSPTCLRALFKKDLPSTPQQLLANRLINAQDKGTTQGDHKKDYRPSLGNEFGMPVAFPKDTDGFPPGLSLKSPSCDGVCKQEVEPDRRSVIFSSGACDRLGTPTHSHPSGNSLEKELSEHMPKGLWAGASQSLPSSQTYSPSTTASDPPLLCRQRPNTSCPVPIKVCPRSPPSETRTRTSSSCSSYSYAEDGSGGSPCSLPQFEFSPSPCPNVTRCLTSDQQEAGGGTDALFARVRPKIKCEQSYGTNSSDESGSFSEGDSESCHVREQGPEVKLPFPVDQITNLPRNDFQMMVKMHKLTSEQLEFIHDVRRRSKNRIAAQRCRKRKLDCILNLECEIRKLVCEKEKLLTERNQLKACMGELWENFSCLSEEVCRDVQLSPEQVHHYCPILRPGNTASVAPGSIDLTASSTPEQSFHKSSSTKDGTTRKPQWKTGNGAEDAANHREEQEAGSAFMEVGLSLEQSNQTVTVDFCQEMTDKCTTDEQPNRKDCT", "length": 823 }, "evidence": [ { "id": "E1BIQ6", "url": "https://omabrowser.org/oma/group/E1BIQ6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9BYV9-1", "protein_name": "Transcription regulator protein BACH2", "gene_name": "BACH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVDEKPDSPMYVYESTVHCTNILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKNDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMHNLEDSCFSFLQTQLLNSEDGLFVCRKDAACQRPHEDCENSAGEEEDEEEETMDSETAKMACPRDQMLPEPISFEAAAIPVAEKEEALLPEPDVPTDTKESSEKDALTQYPRYKKYQLACTKNVYNASSHSTSGFASTFREDNSSNSLKPGLARGQIKSEPPSEENEEESITLCLSGDEPDAKDRAGDVEMDRKQPSPAPTPTAPAGAACLERSRSVASPSCLRSLFSITKSVELSGLPSTSQQHFARSPACPFDKGITQGDLKTDYTPFTGNYGQPHVGQKEVSNFTMGSPLRGPGLEALCKQEGELDRRSVIFSSSACDQVSTSVHSYSGVSSLDKDLSEPVPKGLWVGAGQSLPSSQAYSHGGLMADHLPGRMRPNTSCPVPIKVCPRSPPLETRTRTSSSCSSYSYAEDGSGGSPCSLPLCEFSSSPCSQGARFLATEHQEPGLMGDGMYNQVRPQIKCEQSYGTNSSDESGSFSEADSESCPVQDRGQEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDVRRRSKNRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNQLKACMGELLDNFSCLSQEVCRDIQSPEQIQALHRYCPVLRPMDLPTASSINPAPLGAEQNIAASQCAVGENVPCCLEPGAAPPGPPWAPSNTSENCTSGRRLEGTDPGTFSERGPPLEPRSQTVTVDFCQEMTDKCTTDEQPRKDYT", "length": 841 }, "evidence": [ { "id": "E1BIQ6", "url": "https://omabrowser.org/oma/group/E1BIQ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BIQ6", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BIQ6", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BIQ6", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BIQ6", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6" } ], "pmid": "" }, { "name": "primary adaptive immune response involving T cells and B cells", "id": "GO:0090721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090721", "evidence": [ { "database": "UniProtKB", "id": "E1BIQ6", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BIQ6", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BIQ6", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BIQ6", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BIQ6", "url": "https://www.uniprot.org/uniprotkb/E1BIQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 707, "end_pos": 709, "annotation": "n_glycosylation_sequon" }, { "start_pos": 787, "end_pos": 789, "annotation": "n_glycosylation_sequon" }, { "start_pos": 791, "end_pos": 793, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 590, "end_pos": 592 }, { "start_pos": 707, "end_pos": 709 }, { "start_pos": 787, "end_pos": 789 }, { "start_pos": 791, "end_pos": 793 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGQ5-1", "uniprot_ac": "E1BGQ5", "uniprot_id": "E1BGQ5_BOVIN", "mass": { "chemical_mass": 112920.0, "monoisotopic_mass": 112920.0 }, "refseq": { "ac": "XP_010817643", "name": "centriolar coiled-coil protein of 110 kDa isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817643" }, "gene_names": [ { "name": "CCP110", "type": "recommended", "evidence": [ { "id": "E1BGQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5" } ] }, { "name": "CCP110", "type": "synonym", "evidence": [ { "id": "XP_010817643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817643" } ] } ], "protein_names": [ { "name": "Centriolar coiled-coil protein 110", "type": "synonym", "evidence": [ { "id": "E1BGQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5/entry#names_and_taxonomy" } ] }, { "name": "centriolar coiled-coil protein of 110 kDa isoform X3", "type": "synonym", "evidence": [ { "id": "XP_010817643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817643" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGQ5", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCP110", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5", "locus": { "chromosome": "25", "start_pos": 17154325, "end_pos": 17132697, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003960", "url": "https://www.ensembl.org/id/ENSBTAG00000003960" } ] } } ], "crossref": [ { "id": "E1BGQ5", "url": "https://alphafold.ebi.ac.uk/entry/E1BGQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003960", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003960", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538197", "url": "https://www.ncbi.nlm.nih.gov/gene/538197", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538197", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538197", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFKSNGV", "url": "https://omabrowser.org/oma/group/QFKSNGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGQ5", "url": "https://www.orthodb.org/?gene=E1BGQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13594", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13594", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13594:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13594:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013424", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010817643", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817643", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MM78", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MM78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MM78-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MM78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLL3", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLL3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGQ5", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGQ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEYEKFCEKSLSRIQEASLSTESFLPVQSESISLIRFHGVAVLSPLLNIEKRKEMQQEKQKALDVEARRQVNRKKALLSRVQEILENVQVRKAPDASDFHQWETETVYSNSEVRNLNVPATLPNILPSPTEHSTLAEFEKITGILPLNNEDRFKSNRIDLARDSEELSYLKQCDSSNISQAENEASLKTSSTAAQETLTSDVLFPTNEEQDPSLLEEVTPDPYIMSLQNLMKKSKEYIEREQSRRSLRSSVKRSVNESHSDKENDAVKVTDNGKEKSPLIGKHCGSVIPDKPSLNKSNVLLQGAFTQASSMNTSVLGNFSKVDISIRTGHTTVLETDSNFQGIPTFVTENNVIKSLTGSYAKIPSPEPSLSPKMHRRRSRPSSACHILINNPINASELSPKGKEQAVELVVQETDEKTNVPETVPKLPVCSSKVYVSKNTEAIQEMVLGKSNQVCQPSGNQLENKVIHGLAIMEGQLISDARGPHRVDSTCTAGERLHEPYATRECVLSQNFGSVSGVKSTNVLEKNSCNLQMELNKSYDVKNPSPLLMQNQNTRQQMDTPTVSCGKEQFLDNSFGKVKRRLDLDIDNLQKENYPYVVTTGIAEQERQHLPEKRYSKGSVYIKNKMLESSSKEGEEILKSKILAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKDIEEQEKMLKEKTIITAEASELDISNAVDFGWRKISDSGLLDTVLSQVDSLHTSNSNSSGFTSSALQHSFASANEVPFYLWGSSSSGLTKLSVTRPFGRAKTKWSQVFSPEVQAKLNKVTAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPSKKFLVKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKSSQSRVPSRAPVSGVYAGKIQRKRPNVATI", "length": 1006, "header": "tr|E1BGQ5-1|E1BGQ5_BOVIN Isoform 1 of Centriolar coiled-coil protein 110 OS=Bos taurus OX=9913 GN=CCP110 PE=4 SV=3 CANONICAL=E1BGQ5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MM78-1", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5/entry#A0A3Q1MM78-1", "sequence": { "sequence": "MEEYEKFCEKSLSRIQEASLSTESFLPVQSESISLIRFHGVAVLSPLLNIEKRKEMQQEKQKALDVEARRQVNRKKALLSRVQEILENVQVRKAPDASDFHQWETETVYSNSEVRNLNVPATLPNILPSPTEHSTLAEFEKITGILPLNNEDRFKSNRIDLARDSEELSYLKQCDSSNISQAENEASLKTSSTAAQETLTSDVLFPTNEEQDPSLLEEVTPDPYIMSLQNLMKKSKEYIEREQSRRSLRSSVKRSVNESHSDKENDAVKVTDNGKEKSPLIGKHCGSVIPDKPSLNKSNVLLQGAFTQASSMNTSVLGNFSKVDISIRTGHTTVLETDSNFQGIPTFVTENNVIKSLTGSYAKIPSPEPSLSPKMHRRRSRPSSACHILINNPINASELSPKGKEQAVELVVQETDEKTNVPETVPKLPVCSSKVYVSKNTEAIQEMVLGKSNQVCQPSGNQLENKVIHGLAIMEGQLISDARGPHRVDSTCTAGERLHEPYATRECVLSQNFGSVSGVKSTNVLEKNSCNLQMELNKSYDVKNPSPLLMQNQNTRQQMDTPTVSCGKEQFLDNSFGKVKRRLDLDIDNLQKENYPYVVTTGIAEQERQHLPEKRYSKGSVYIKNKMLESSSKEGEEILKSKILAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKDIEEQEKMLKEKTIITAEASELDISNAVDFGWRKISDSGLLDTVLSQVDSLHTSNSNSSGFTSSALQHSFASANEVPFYLWGSSSSGLTKLSVTRPFGRAKTKWSQVFSPEVQAKLNKVTAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQMGIFSTQGSNLSLLCLLQWQDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPSKKFLVKQNPSETRVLQPNQGQNAPVHRLLSRQGSICRKNPKKAAKCCDNLRRQHSLG", "length": 1004, "header": "tr|A0A3Q1MM78-1|E1BGQ5_BOVIN Computationally mapped isoform of Centriolar coiled-coil protein 110 OS=Bos taurus OX=9913 GN=CCP110 PE=4 SV=1 CANONICAL=E1BGQ5-1" }, "locus": { "chromosome": "25", "start_pos": 17153321, "end_pos": 17136534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069171.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069171.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070489.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070489.2" } ] } }, { "isoform_ac": "A0AAF6DLL3-1", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5/entry#A0AAF6DLL3-1", "sequence": { "sequence": "MEEYEKFCEKSLSRIQEASLSTESFLPVQSESISLIRFHGVAVLSPLVRKAPDASDFHQWETETVYSNSEVRNLNVPATLPNILPSPTEHSTLAEFEKITGILPLNNEDRFKSNRIDLARDSEELSYLKQCDSSNISQAENEASLKTSSTAAQETLTSDVLFPTNEEQDPSLLEEVTPDPYIMSLQNLMKKSKEYIEREQSRRSLRSSVKRSVNESHSDKENDAVKVTDNGKEKSPLIGKHCGSVIPDKPSLNKSNVLLQGAFTQASSMNTSVLGNFSKVDISIRTGHTTVLETDSNFQGIPTFVTENNVIKSLTGSYAKIPSPEPSLSPKMHRRRSRPSSACHILINNPINASELSPKGKEQAVELVVQETDEKTNVPETVPKLPVCSSKVYVSKNTEAIQEMVLGKSNQVCQPSGNQLENKVIHGLAIMEGQLISDARGPHRVDSTCTAGERLHEPYATRECVLSQNFGSVSGVKSTNVLEKNSCNLQMELNKSYDVKNPSPLLMQNQNTRQQMDTPTVSCGKEQFLDNSFGKVKRRLDLDIDNLQKENYPYVVTTGIAEQERQHLPEKRYSKGSVYIKNKMLESSSKEGEEILKSKILAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKDIEEQEKMLKEKTIITAEASELDISNAVDFGWRKISDSGLLDTVLSQVDSLHTSNSNSSGFTSSALQHSFASANEVPFYLWGSSSSGLTKLSVTRPFGRAKTKWSQVFSPEVQAKLNKVTAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPSKKFLVKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKSSQSRVPSRAPVSGVYAGKIQRKRPNVATI", "length": 963, "header": "tr|A0AAF6DLL3-1|E1BGQ5_BOVIN Computationally mapped isoform of Centriolar coiled-coil protein 110 OS=Bos taurus OX=9913 GN=CCP110 PE=4 SV=2 CANONICAL=E1BGQ5-1" }, "locus": { "chromosome": "25", "start_pos": 17153298, "end_pos": 17136534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063871.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063871.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055461.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055461.3" } ] } }, { "isoform_ac": "E1BGQ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5/entry#E1BGQ5-1", "sequence": { "sequence": "MEEYEKFCEKSLSRIQEASLSTESFLPVQSESISLIRFHGVAVLSPLLNIEKRKEMQQEKQKALDVEARRQVNRKKALLSRVQEILENVQVRKAPDASDFHQWETETVYSNSEVRNLNVPATLPNILPSPTEHSTLAEFEKITGILPLNNEDRFKSNRIDLARDSEELSYLKQCDSSNISQAENEASLKTSSTAAQETLTSDVLFPTNEEQDPSLLEEVTPDPYIMSLQNLMKKSKEYIEREQSRRSLRSSVKRSVNESHSDKENDAVKVTDNGKEKSPLIGKHCGSVIPDKPSLNKSNVLLQGAFTQASSMNTSVLGNFSKVDISIRTGHTTVLETDSNFQGIPTFVTENNVIKSLTGSYAKIPSPEPSLSPKMHRRRSRPSSACHILINNPINASELSPKGKEQAVELVVQETDEKTNVPETVPKLPVCSSKVYVSKNTEAIQEMVLGKSNQVCQPSGNQLENKVIHGLAIMEGQLISDARGPHRVDSTCTAGERLHEPYATRECVLSQNFGSVSGVKSTNVLEKNSCNLQMELNKSYDVKNPSPLLMQNQNTRQQMDTPTVSCGKEQFLDNSFGKVKRRLDLDIDNLQKENYPYVVTTGIAEQERQHLPEKRYSKGSVYIKNKMLESSSKEGEEILKSKILAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKDIEEQEKMLKEKTIITAEASELDISNAVDFGWRKISDSGLLDTVLSQVDSLHTSNSNSSGFTSSALQHSFASANEVPFYLWGSSSSGLTKLSVTRPFGRAKTKWSQVFSPEVQAKLNKVTAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPSKKFLVKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKSSQSRVPSRAPVSGVYAGKIQRKRPNVATI", "length": 1006, "header": "tr|E1BGQ5-1|E1BGQ5_BOVIN Isoform 1 of Centriolar coiled-coil protein 110 OS=Bos taurus OX=9913 GN=CCP110 PE=4 SV=3 CANONICAL=E1BGQ5-1" }, "locus": { "chromosome": "25", "start_pos": 17153298, "end_pos": 17136534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005166.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005166.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005166.5", "url": "https://www.ensembl.org/id/ENSBTAP00000005166.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538197", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538197", "resource": "KEGG Pathway" }, { "id": "R-BTA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-BTA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-BTA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-BTA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-BTA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-BTA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-BTA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-BTA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" }, { "id": "R-BTA-9013424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013424", "resource": "Reactome", "description": "RHOV GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZT05-1", "protein_name": "Centriolar coiled-coil protein 110", "gene_name": "Ccp110", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEYEKFCEKALARAQEASLSTDSFLPAQAESVSLIRFHGVAVLSPLLTIEKREKIQQEKQKALDVQTRKQANRKKALLTRVQEILENVQVRKAPNASDFDQWATETIASNSEVTGLSVPVTVPSDLLSPTEHCTSGKLGKTTGLLPVNNEDQQSPERMGLPKDSEVFGSLKQCESPGSRWAENGAAPRLSSASSQETVISDDPLLAKEEQEPSCLAEVTPDPYIISLQNLMKRSKEYVEREQSSWSLRSSLKKSVHETHSDKENDAAKASDCVKEKAPPMPVGRHCGSAIPDKPSLNKSNVLLQGASQASSLGTSVLASFLKTDLPVGTGPPTVPDAESDFKVIPTFVTENKVKSLIGPYAKLPSPEPSMSPTMHRRHSRSSSACQILINNPVNACELSPKGKEEAVDRIAPAAAETNESEIVPKPPTDLTGVGSSKVSATKVMSDTIREMVMGKPSQVHQALGNQLGNNVTVEQFAMEGPFIPDGRGMQKVDGTCIAVPKLHELQPTSQCVSSQTLEDACGLKAASVLAKNSCNVQMELNKSYDVKRPSPLLMQTQNSRQQMDTPPVPRGNEQFVDNSFEKVKRRLDLDVDSLQKENCPHILTAGSAEQERERPPERRYPKGSVYGNKNKMLETSPKEGQELLKSKMLAFEEMRKRLEEQHVQQLSLLIAEQEREQEQLQKEIEEQEKMLKEKAVTTDVSGLNSALELEWRKRSDPAFLETMLSQVDSLQTSNNSGFLSSALQYSFGSASEVPLYLRGSLTSGVTKLSVTRPFGRAQPKWSQVFSPEIQAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMRSPRVALSVATQKSLDRKKFMKVAEMGMANKKFLLKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGAYAGKTQRKRPNVATI", "length": 1007 }, "evidence": [ { "id": "E1BGQ5", "url": "https://omabrowser.org/oma/group/E1BGQ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZH40-1", "protein_name": "Centriolar coiled-coil protein 110", "gene_name": "CCP110", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKMEDYETFCKKHLSRIQEEATKGENSSTSLDRNVSLIQFHGVPVLSPLLSFEKRKEIQQYRQKALDLETWRQNSHKRALLNRVQEILENIQNRKVSGKSDVNTWDAENTCPDSDSKALTDLAAVSDANLPCSPERHCSVQLEKSQELLPPDSMQQVTSNATEVGKPAEENVPSKESGSHFSRDVPCPRAASPDSVQSKLVSPALQKQEGQGVPSSDKEVQDPYAVSLQNLMKKSREYIEKEQSRRSSKSSSKKSMNESHSDKENDAVKTSDPVKERVKLTGRSSTALPLDKPCLNKSNAHIQGASTHTSNTSMSTLSSFSKVDIPMRVGTPPLVDSDSDEEFKNTSTIDRDSSIVRSLTGSYTKLPSPEPSMSPKMHRRRPRPLSMGHIVINNPVNAYELSPKGKGRAMDLIMQDIADKNNVSESVPKFMMDFSMLCPSRVPGVLRSSSGPSDGLLVGKPNRHSFGHSEGKGTLSAAMEGQVVMDNRGPYKVETGTVGSKLNEPFSINQSTVTQKLLAVNETKASSLQENTKSPVELNKSYDVESPSPLLMQSKSMHQQMDTPSIPPANEQFLENSFEKVKRRLDLDTDDCQKDNNPCVVTVGMEEQERQWLQEQKYPVTSVYITKNAASDSSMAKEEILKTKMLAFEEMRKRLEEQHAQQLSILIAEQEREQEKLQKELEEQERKGKKIATTEIEISKVNINSRMELEWRKSESGLVESVQSQLETIHNANSTSIGFAHTTSPNTFTSTSETSFFLWGPSGSGVIKTSVSRPSNRIKTRWTQIFTPEIQMKFDKITAVAKGFLTRRLLQTEKLKHLKQTVKDTMEFIRNFQSEAPLKRGSVSAQDASLHERVMAQLRAALYDIHDIFFTMEASERMNILRHDREVRKEKMLRQMDKVKSPRERATLSTATQKSLDRKKYMKASEMGMPSKKIVIKQRSPESRVLQPNQGQNAPVHRLLCRQGTPKTSMKGVEQNRKKASESRVSNKAVSGAYAGRTQRKKPNVVTI", "length": 1008 }, "evidence": [ { "id": "E1BGQ5", "url": "https://omabrowser.org/oma/group/E1BGQ5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O43303-1", "protein_name": "Centriolar coiled-coil protein of 110 kDa", "gene_name": "CCP110", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEYEKFCEKSLARIQEASLSTESFLPAQSESISLIRFHGVAILSPLLNIEKRKEMQQEKQKALDVEARKQVNRKKALLTRVQEILDNVQVRKAPNASDFDQWEMETVYSNSEVRNLNVPATFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKTDGIDLARDSEGFNSPKQCDSSNISHVENEAFPKTSSATPQETLISDGPFSVNEQQDLPLLAEVIPDPYVMSLQNLMKKSKEYIEREQSRRSLRGSINRIVNESHLDKEHDAVEVADCVKEKGQLTGKHCVSVIPDKPSLNKSNVLLQGASTQASSMSMPVLASFSKVDIPIRTGHPTVLESNSDFKVIPTFVTENNVIKSLTGSYAKLPSPEPSMSPKMHRRRSRTSSACHILINNPINACELSPKGKEQAMDLIIQDTDENTNVPEIMPKLPTDLAGVCSSKVYVGKNTSEVKEDVVLGKSNQVCQSSGNHLENKVTHGLVTVEGQLTSDERGAHIMNSTCAAMPKLHEPYASSQCIASPNFGTVSGLKPASMLEKNCSLQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEIQAKFNKITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPNKKFLVKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRVPVSGVYAGKIQRKRPNVATI", "length": 1012 }, "evidence": [ { "id": "E1BGQ5", "url": "https://omabrowser.org/oma/group/E1BGQ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TSH4-1", "protein_name": "Centriolar coiled-coil protein of 110 kDa", "gene_name": "Ccp110", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEYEEFCEKALGRAQEASLSTGSFLPAQAESVSLIRFHGVAVLSPLLTIEKRKKIQEEKQKALDVQSRKQANRKKALLTRVQEILENVQVRKAPNASDFDQWATETIYSNPEVTDLNVPVRVPNSLPSPTEHCTSVKLEKITGLLPVNNEDQQTPKRVGLPGDSEVSGSLRQCESPESRQAEDGAALRLSSASPQETIISDVLGKEEQDPSCLAEVTPDPYIMSLQNLMKRSKEYVERELSSRSLRNSLKRSVNETHSDRENDAAKASDCVKEKAPPMPIGRHCGSAIPDKPSLNKSNVLLQGASQASSMGTAGLASFSKIDLPAGAAPPAAPDAGSDFTVIPTFVTENKVKSLKGPYAKLPSPEPSMSPTMHRRHSRSASACQILINNPVNACELSPKGKEEAVDRTAPAAAETTNESETVPKSPTDLTGVCSSNVSATKITSESTREMVVGKPSQRQQALGAHLGNNVTVERSAMEGPFIADDRGAQKVDGTCMAVPKLHELQPSSQCVSSQTLEDVCELKSASLLAKNSCNLQMELNKSYDVKHPSPLLTQTQTSRQQMDTPPVFRGNEQFVDNSFEKVKRRLDLDVDSLQKENCPYIITAGVAEQERDRLLERRYPKGFVHINKNKMLETSPKEGQELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQEQLQKEIEEQEKMLKEKAVTTDVSDLNSALEWRQRTDSALLETMLSQVDSLQTSNNSGFITSALQYSFGSAGEAPFYLWGSLTSGVTRVSGTRPCGRAQAKWSQVFNPEIHAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMKSPRVALSVATQKSLDRKKFMKVAEMGMPNKKFLLKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGAYAGKTQRKRPNVATI", "length": 1004 }, "evidence": [ { "id": "E1BGQ5", "url": "https://omabrowser.org/oma/group/E1BGQ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1BGQ5", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BGQ5", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "E1BGQ5", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "E1BGQ5", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "E1BGQ5", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5" } ], "pmid": "" }, { "name": "negative regulation of cilium assembly", "id": "GO:1902018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902018", "evidence": [ { "database": "UniProtKB", "id": "E1BGQ5", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5" } ], "pmid": "" }, { "name": "positive regulation of cilium assembly", "id": "GO:0045724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045724", "evidence": [ { "database": "UniProtKB", "id": "E1BGQ5", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5" } ], "pmid": "" }, { "name": "ciliary basal body organization", "id": "GO:0032053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032053", "evidence": [ { "database": "UniProtKB", "id": "E1BGQ5", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BGQ5", "url": "https://www.uniprot.org/uniprotkb/E1BGQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 395, "end_pos": 397 }, { "start_pos": 537, "end_pos": 539 }, { "start_pos": 734, "end_pos": 736 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGH8-1", "uniprot_ac": "E1BGH8", "uniprot_id": "MMS22_BOVIN", "mass": { "chemical_mass": 142274.0, "monoisotopic_mass": 142274.0 }, "refseq": {}, "gene_names": [ { "name": "MMS22L", "type": "recommended", "evidence": [ { "id": "E1BGH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ] } ], "protein_names": [ { "name": "Protein MMS22-like", "type": "recommended", "evidence": [ { "id": "E1BGH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH8/entry#names_and_taxonomy" } ] }, { "name": "Methyl methanesulfonate-sensitivity protein 22-like", "type": "synonym", "evidence": [ { "id": "E1BGH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the MMS22L-TONSL complex, a complex that promotes homologous recombination-mediated repair of double-strand breaks (DSBs) at stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication. It mediates the assembly of RAD51 filaments on single-stranded DNA (ssDNA): the MMS22L-TONSL complex is recruited to DSBs following histone replacement by histone chaperones and eviction of the replication protein A complex (RPA/RP-A) from DSBs. Following recruitment to DSBs, the TONSL-MMS22L complex promotes recruitment of RAD51 filaments and subsequent homologous recombination. Within the complex, MMS22L acts by binding ssDNA.", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8#function" }, { "database": "UniProtKB", "id": "Q6ZRQ5", "url": "https://www.uniprot.org/uniprotkb/Q6ZRQ5#function" }, { "database": "UniProtKB", "id": "A0A3Q1LTN5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTN5#function" }, { "database": "UniProtKB", "id": "ARBA00045147", "url": "https://www.uniprot.org/uniprotkb/ARBA00045147#function" }, { "database": "UniProtKB", "id": "A0A3Q1MDR7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDR7#function" }, { "database": "UniProtKB", "id": "A0A452DHT7", "url": "https://www.uniprot.org/uniprotkb/A0A452DHT7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MMS22L", "url": "https://www.uniprot.org/uniprotkb/E1BGH8", "locus": { "chromosome": "9", "start_pos": 52617857, "end_pos": 52495368, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000629", "url": "https://www.ensembl.org/id/ENSBTAG00000000629" } ] } } ], "crossref": [ { "id": "E1BGH8", "url": "https://alphafold.ebi.ac.uk/entry/E1BGH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000629", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000629", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "532916", "url": "https://www.ncbi.nlm.nih.gov/gene/532916", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532916", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532916", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RVYLCLL", "url": "https://omabrowser.org/oma/group/RVYLCLL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LTN5", "url": "https://www.orthodb.org/?gene=A0A3Q1LTN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MDR7", "url": "https://www.orthodb.org/?gene=A0A3Q1MDR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BGH8", "url": "https://www.orthodb.org/?gene=E1BGH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28547", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28547", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28547:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28547:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14910", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14910", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14911", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14911", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LTN5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDR7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DHT7", "url": "https://www.uniprot.org/uniprotkb/A0A452DHT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DHT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DHT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNCPPASTFLTDSLELELQTEWCNPPCFSCDFDNRGGGKHFSGESYLSSGALKRVILNLDPLPTNFEEDTVEIFGIEWVTETALVNSSRVLFHLFRQQLYNLETLLQASCDFGKISTLHCKAHNIRQLCVTFLHYVKVFIFRSLQVRNAESHVPVHPYETLEAQLPSVLVDELHGLLLYIGHLSELPTTNTGAFVNQNQTKLYPPSWHLLHLHLDIHWLVLEILHMLGEKLKQVVYSHQFMNLAGDNLTNVSLFEEHCENLLCDLINLSLNRYDKKVRPSEALMSHHCPCPCIKELWVLLIHLLNHRSKWSLSESFWNWLNKLLKTLLEKSNDQRRSVLIVQPRDPLGFSWWIITHVASFYQFDRHGTPDEMRQMESNWNFVEELLKKSISVQDGILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPLKGLTYIIKSPLSMLEMVKTCCCDKQDHDLYKSSSSYTIFLCILAKVVKKAMKNNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLRLLDFLKPTFKTSPLIWKGQMAFLLMYTQKNLDIGVLAEKFSNAFREKAKEFLVSKNDEMGQRQTLWTLLSIYMDSVQEVFETSRCLHPSHEKLLNDGFSMLLRACQESELRTVLNFLQAVLARIRSLHQQLRQELQREHGDLSVQSSLSTKERHLAAVASALWRHFFSFLKSQRMSQIVPLSQLADAAADFTLLAMDLPSTAPSDLQPQPVTSMIQLFGWDDIIWPQVVARYLSHFLQNSMLCEALSHSGCVSFQALTVRSWIRCILQMYVKNLHVPDDSFIDINPEQAVEKDYMEQLTELTRLLFKLSEVKNIFSKSQVELPIPDDPKKALIRFFEAVGITYGNLQTVSDKSAMVTKSLEYLGEILKYIKPYLGKKVSSAGLQLTYTMMGTLVKSWALIFATSKAQKLLFRIIDCLLLPHTVLQQEKELPAPMLTAIQKSLPLYLQGMCIVCCQSQNTNAYLNQLLGNVIEQYIGRFLPASAHVLGLGQHPVLLALKNSASVPPMSLLKKCIVHVIRKSYFEFKGSLLPPRLASILAFILQLVKETNTDVSEIELLLPGVLKCLLLVSEPQVKRLATENLQCMVRACQVGSGGEPAAQLTSVFRQFIEDYGMRYDYQIYSILEAVAALDQQVVIHLVPTLTQSLKNSERKWGLGRNSAQREAYSKLLSQLGQVGQDEIQRLENDHIESML", "length": 1244, "header": "sp|E1BGH8-1|MMS22_BOVIN Isoform 1 of Protein MMS22-like OS=Bos taurus OX=9913 GN=MMS22L PE=3 SV=1 CANONICAL=E1BGH8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LTN5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGH8/entry#A0A3Q1LTN5-1", "sequence": { "sequence": "MLFRSWSNLVTAYGKISTLHCKAHNIRQLCVTFLHYVKVFIFRSLQVRNAESHVPVHPYETLEAQLPSVLVDELHGLLLYIGHLSELPTTNTGAFVNQNQTKLYPPSWHLLHLHLDIHWLVLEILHMLGEKLKQVVYSHQFMNLAGDNLTNVSLFEEHCENLLCDLINLSLNRYDKVRPSEALMSHHCPCPCIKELWVLLIHLLNHRSKWSLSESFWNWLNKLLKTLLEKSNDQRRSVLIVQPRDPLGFSWWIITHVASFYQFDRHGTPDEMRQMESNWNFVEELLKKSISVQDGILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPLKGLTYIIKSPLSMLEMVKTCCCDKQDHDLYKSSSSYTIFLCILAKVVKKAMKNNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLRLLDFLKPTFKTSPLIWKGQMAFLLMYTQKNLDIGVLAEKFSNAFREKAKEFLVSKNDEMGQRQTLWTLLSIYMDSVQEVFETSRCLHPSHEKLLNDGFSMLLRACQESELRTVLNFLQAVLARIRSLHQQLRQELQREHGDLSVQSSLSTKERHLAAVASALWRHFFSFLKSQRMSQIVPLSQLADAAADFTLLAMDLPSTAPSDLQPQPVTSMIQLFGWDDIIWPQVVARYLSHFLQNSMLCEALSHSGCVSFQALTVRSWIRCILQMYVKNLHVPDDSFIDINPEQAVEKDYMEQLTELTRLLFKLSEVKNIFSKSQVELPIPDDPKKALIRFFEAVGITYGNLQTVSDKSAMVTKSLEYLGEILKYIKPYLGKKVSSAGLQLTYTMMGTLVKSWALIFATSKAQKLLFRIIDCLLLPHTVLQQEKELPAPMLTAIQKSLPLYLQGMCIVCCQSQNTNAYLNQLLGNVIEQYIGRFLPASAHVLGLGQHPVLLALKNSASVPPMSLLKKCIVHVIRKSYFEFKGSLLPPRLASILAFILQLVKETNTDVSEIELLLPGVLKCLLLVSEPQVKRLATENLQCMVRACQVGSGGEPAAQLTSVFRQFIEDYGMRYDYQIYSILEAVAALDQQVVIHLVPTLTQSLKNSERKWGLGRNSAQREAYSKLLSQLGQVGQDEIQRLENDHIESML", "length": 1143, "header": "tr|A0A3Q1LTN5-1|MMS22_BOVIN Computationally mapped isoform of Protein MMS22-like OS=Bos taurus OX=9913 GN=MMS22L PE=3 SV=2 CANONICAL=E1BGH8-1" }, "locus": { "chromosome": "9", "start_pos": 52617673, "end_pos": 52501956, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087328.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087328.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060442.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060442.2" } ] } }, { "isoform_ac": "A0A3Q1MDR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BGH8/entry#A0A3Q1MDR7-1", "sequence": { "sequence": "MDNCPPASTFLTDSLELELQTEWCNPPCFSCDFDNRGGGKHFSGESYLSSGALKRVILNLDPLPTNFEEDTVEIFGIEWVTETALVNSSRVLFHLFRQQLYNLETLLQASCDFGKISTLHCKAHNIRQLCVTFLHYVKVFIFRSLQVRNAESHVPVHPYETLEAQLPSVLVDELHGLLLYIGHLSELPTTNTGAFVNQNQTKLYPPSWHLLHLHLDIHWLVLEILHMLGEKLKQVVYSHQFMNLAGDNLTNVSLFEEHCENLLCDLINLSLNRYDKVRPSEALMSHHCPCPCIKELWVLLIHLLNHRSKWSLSESFWNWLNKLLKTLLEKSNDQRRSVLIVQPRDPLGFSWWIITHVASFYQFDRHGTPDEMRQMESNWNFVEELLKKSISVQNSSFSISWLPLKGLTYIIKSPLSMLEMVKTCCCDKQDHDLYKSSSSYTIFLCILAKVVKKAMKNNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLRLLDFLKPTFKTSPLIWKGQMAFLLMYTQKNLDIGVLAEKFSNAFREKAKEFLVSKNDEMGQRQTLWTLLSIYMDSVQEVFETSRCLHPSHEKLLNDGFSMLLRACQESELRTVLNFLQAVLARIRSLHQQLRQELQREHGDLSVQSSLSTKERHLAAVASALWRHFFSFLKSQRMSQIVPLSQLADAAADFTLLAMDLPSTAPSDLQPQPVTSMIQLFGWDDIIWPQVVARYLSHFLQNSMLCEALSHSGCVSFQALTVRSWIRCILQMYVKNLHVPDDSFIDINPEQAVEKDYMEQLTELTRLLFKLSEVKNIFSKSQVELPIPDDPKKALIRFFEAVGITYGNLQTVSDKSAMVTKSLEYLGEILKYIKPYLGKKVSSAGLQLTYTMMGTLVKSWALIFATSKAQKLLFRIIDCLLLPHTVLQQEKELPAPMLTAIQKSLPLYLQGMCIVCCQSQNTNAYLNQLLGNVIEQYIGRFLPASAHVLGLGQHPVLLALKNSASVPPMSLLKKCIVHVIRKSYFEFKGSLLPPRLASILAFILQLVKETNTDVSEIELLLPGVLKCLLLVSEPQVKRLATENLQCMVRACQVGSGGEPAAQLTSVFRQFIEDYGMRYDYQIYSILEAVAALDQQVVIHLVPTLTQSLKNSERKWGLGRNSAQREAYSKLLSQLGQVGQDEIQRLENDHIESML", "length": 1203, "header": "tr|A0A3Q1MDR7-1|MMS22_BOVIN Computationally mapped isoform of Protein MMS22-like OS=Bos taurus OX=9913 GN=MMS22L PE=3 SV=1 CANONICAL=E1BGH8-1" }, "locus": { "chromosome": "9", "start_pos": 52617673, "end_pos": 52496313, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081269.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081269.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072278.1", "url": "https://www.ensembl.org/id/ENSBTAP00000072278.1" } ] } }, { "isoform_ac": "A0A452DHT7-1", "url": "https://www.uniprot.org/uniprotkb/E1BGH8/entry#A0A452DHT7-1", "sequence": { "sequence": "MDNCPPASTFLTDSLELELQTEWCNPPCFSCDFDNRGGGKHFSGESYLSSGALKRVILNLDPLPTNFEEDTVEIFGIEWVTETALVNSSRVLFHLFRQQLYNLETLLQASCDFGKISTLHCKAHNIRQLCVTFLHYVKVFIFRSLQVRNAESHVPVHPYETLEAQLPSVLVDELHGLLLYIGHLSELPTTNTGAFVNQNQTKLYPPSWHLLHLHLDIHWLVLEILHMLGEKLKQVVYSHQFMNLAGDNLTNVSLFEEHCENLLCDLINLSLNRYDKVRPSEALMSHHCPCPCIKELWVLLIHLLNHRSKWSLSESFWNWLNKLLKTLLEKSNDQRRSVLIVQPRDPLGFSWWIITHVASFYQFDRHGTPDEMRQMESNWNFVEELLKKSISVQDGILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPLKGLTYIIKSPLSMLEMVKTCCCDKQDHDLYKSSSSYTIFLCILAKVVKKAMKNNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLRLLDFLKPTFKTSPLIWKGQMAFLLMYTQKNLDIGVLAEKFSNAFREKAKEFLVSKNDEMGQRQTLWTLLSIYMDSVQEVFETSRCLHPSHEKLLNDGFSMLLRACQESELRTVLNFLQAVLARIRSLHQQLRQELQREHGDLSVQSSLSTKERHLAAVASALWRHFFSFLKSQRMSQIVPLSQLADAAADFTLLAMDLPSTAPSDLQPQPVTSMIQLFGWDDIIWPQVVARYLSHFLQNSMLCEALSHSGCVSFQALTVRSWIRCILQMYVKNLHVPDDSFIDINPEQAVEKDYMEQLTELTRLLFKLSEVKNIFSKSQVELPIPDDPKKALIRFFEAVGITYGNLQTVSDKSAMVTKSLEYLGEILKYIKPYLGKKVSSAGLQLTYTMMGTLVKSWALIFATSKAQKLLFRIIDCLLLPHTVLQQEKELPAPMLTAIQKSLPLYLQGMCIVCCQSQNTNAYLNQLLGNVIEQYIGRFLPASAHVLGLGQHPVLLALKNSASVPPMSLLKKCIVHVIRKSYFEFKGSLLPPRLASILAFILQLVKETNTDVSEIELLLPGVLKCLLLVSEPQVKRLATENLQCMVRACQVGSGGEPAAQLTSVFRQFIEDYGMRYDYQIYSILEAVAALDQQVVIHLVPTLTQSLKNSERKWGLGRNSAQREAYSKLLSQLGQVGQDEIQRLENDHIESML", "length": 1243, "header": "tr|A0A452DHT7-1|MMS22_BOVIN Computationally mapped isoform of Protein MMS22-like OS=Bos taurus OX=9913 GN=MMS22L PE=3 SV=1 CANONICAL=E1BGH8-1" }, "locus": { "chromosome": "9", "start_pos": 52617673, "end_pos": 52496313, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000830.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000830.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000830.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000830.6" } ] } }, { "isoform_ac": "E1BGH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGH8/entry#E1BGH8-1", "sequence": { "sequence": "MDNCPPASTFLTDSLELELQTEWCNPPCFSCDFDNRGGGKHFSGESYLSSGALKRVILNLDPLPTNFEEDTVEIFGIEWVTETALVNSSRVLFHLFRQQLYNLETLLQASCDFGKISTLHCKAHNIRQLCVTFLHYVKVFIFRSLQVRNAESHVPVHPYETLEAQLPSVLVDELHGLLLYIGHLSELPTTNTGAFVNQNQTKLYPPSWHLLHLHLDIHWLVLEILHMLGEKLKQVVYSHQFMNLAGDNLTNVSLFEEHCENLLCDLINLSLNRYDKKVRPSEALMSHHCPCPCIKELWVLLIHLLNHRSKWSLSESFWNWLNKLLKTLLEKSNDQRRSVLIVQPRDPLGFSWWIITHVASFYQFDRHGTPDEMRQMESNWNFVEELLKKSISVQDGILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPLKGLTYIIKSPLSMLEMVKTCCCDKQDHDLYKSSSSYTIFLCILAKVVKKAMKNNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLRLLDFLKPTFKTSPLIWKGQMAFLLMYTQKNLDIGVLAEKFSNAFREKAKEFLVSKNDEMGQRQTLWTLLSIYMDSVQEVFETSRCLHPSHEKLLNDGFSMLLRACQESELRTVLNFLQAVLARIRSLHQQLRQELQREHGDLSVQSSLSTKERHLAAVASALWRHFFSFLKSQRMSQIVPLSQLADAAADFTLLAMDLPSTAPSDLQPQPVTSMIQLFGWDDIIWPQVVARYLSHFLQNSMLCEALSHSGCVSFQALTVRSWIRCILQMYVKNLHVPDDSFIDINPEQAVEKDYMEQLTELTRLLFKLSEVKNIFSKSQVELPIPDDPKKALIRFFEAVGITYGNLQTVSDKSAMVTKSLEYLGEILKYIKPYLGKKVSSAGLQLTYTMMGTLVKSWALIFATSKAQKLLFRIIDCLLLPHTVLQQEKELPAPMLTAIQKSLPLYLQGMCIVCCQSQNTNAYLNQLLGNVIEQYIGRFLPASAHVLGLGQHPVLLALKNSASVPPMSLLKKCIVHVIRKSYFEFKGSLLPPRLASILAFILQLVKETNTDVSEIELLLPGVLKCLLLVSEPQVKRLATENLQCMVRACQVGSGGEPAAQLTSVFRQFIEDYGMRYDYQIYSILEAVAALDQQVVIHLVPTLTQSLKNSERKWGLGRNSAQREAYSKLLSQLGQVGQDEIQRLENDHIESML", "length": 1244, "header": "sp|E1BGH8-1|MMS22_BOVIN Isoform 1 of Protein MMS22-like OS=Bos taurus OX=9913 GN=MMS22L PE=3 SV=1 CANONICAL=E1BGH8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532916", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532916", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ALT1-1", "protein_name": "Protein MMS22-like", "gene_name": "MMS22L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDSCSAASTFLTDSLELELEREWCNPPCFSCDFDNRGGGRHFSGESYLSSGALKRLILNLDPLPTNFEEDTVEIFGIQWVTETALVNSSRVLFHLFRQQLYNLETLLHANCDFGKISTLHCKAANIRQQCVTFLHYVKVFIFRSLKVQNAESHVSVHPYEALEAQLPSVLVDELHGLLLYIGHLSEFPSINAGAFVNQNQTKLFPPSWHLLHLHLDIHWLVLEILHMLGEKSKQVVYSHQFMNLTGDNLTNVSLFEEHCENLLYNLISLSLNRYDKVRPSEALMSHHCACPCIKELWILFIHLLDHRSKWSHSESFWHWLNKLLKTVFEKSNDQRRPSVPLIQPRDPLGFTWWIITHVASFYRFDRHGAPDEMRQMESNWNFVEELLKKSINVQDGVLEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPLKGLAYIVKSPLSMLEMVKTCCCDKQDHDLYKSSSSYTIFLCILAKVVKKAMKSNGLHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLGLLNFLKPAFMTSPLIWKGQMAFLLMYTQKNLDISVLAEKFSGAFREKAKEFLVSKNDDMGQRQTLWTLLSIYIDGVQEVFETSHCLHPSHEKLLNDGFSMLLRACQESELRTLLGFLQALLARIRSMHQQLCQELQRENSDLVVQSSLAAKERHLAAVASTLWRHFFSFLKSQRMSQIVPLSQLADAAADFTLLAVDLPSTAPSDLQPQPVLSLIQLFGWDDIIWPQVVARYLSHVLQNSMLCEALSHSGCVSFQALTVRSWIRCTLQMYIKNLYVPDDSFIDTNPEQAVEKDYMEQLTELTRLLFKLPEVKDILSKAQVEYLLIPEDPKKALVRFLEAVGITYGNLQTLSDKSAMVTKSLEYLGEILKYIKPYLGKKISSAGLQLTYMMMGVLVKSWAQIFATSKAQKLLFRIIDCLLLPHTVLQQEKELPAPMLTAIQKSLPLYLQGMCVVCCQSQNPNTYLSQLLGNVIELYIGRFLPTSPHGLGVGQHPVLLALRNSATVPLMSSLKKCILQVIRKSYFDFKGSLLPPRLASVLAFILQLVKETNIDVSEIELLLPGVLKCLVLVSEPQVKRLATENLQYMVKSCQVGSGGEPAAQLTSVFRQFIEDYGMRYNYQIYSILETVAALDQQVVINLISTLTQSLKSSERKWGLGRNIAQREAYSKLLSHLGQVGQDEIQRLENDNTESIL", "length": 1245 }, "evidence": [ { "id": "E1BGH8", "url": "https://omabrowser.org/oma/group/E1BGH8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B1AUR6-1", "protein_name": "Protein MMS22-like", "gene_name": "Mms22l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGCSAASTFLTDSLELELGTEWCKPPCFSCAFDNREGKFSGESYLASGALKRLILNLDPLPTNFEEDTVELFGFQWVTETALVYSCRELFHLFRQQIFNLESLVQVSCDFGKIATLHAKADSIRQQCVVFLHYIKVFIFRCLKVQEAESHSRPAHPYEALEAQLPSMLVDELRGLLLYIGHLAALPSVTVGAFVNQNQMKLFPPSWHLLHLYLDTHWLVLEILHILGEKLKQVVYGRQFIGQAGDNLTNVSLFEEHCEHLFCDLICLSLNRFDKVMPSEALLISHCPCSCVKELWVLLIHLLDHRRKWSVADSFWNWLNKLLRTLFEKSSDQRRSSVSLTQAKDPLGFSWWISVHVASLYQIDRHGVSDKMKQMESNWSFIEELLKRSVTVQDSILEEQLRMHLHCCLTLCDFWEPNISVVTILWEYYSKNLNSSFSISWLPLKGLTNIIKSPLSMLTLVRNCCSDKQDPDLYKSSSSYIIFLCILAKVVKKAMRTSGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEIEDVASHVLDLLRFLRPASMSSHGALVWKGQMAFLLMYAQKNLDIGVWAEKLSCEFQEKAKEFLVSKNDEMVQRHALWTLLCIYIDGVQEVFETSSCLYPSHEHLLNDGFSMLLPACRESELRTVLNFLQAVLARIRSVHQQLCQELQRENVDLTVQSSLSAKERPLAAVAGALWRHFFSFLKSQRMTQVVPLSQLADAAADFTLLAVDMPNTAPPDLQPQPVISIIQLFGWDDIIWPQVVARYLSHLLQNSTVYEALSQSSCVSSQSLTIRSWVRCVLQMHIKHLSDPDLLIDVNPEQAVEKEYMEQLAEMTRLLFTLSEVKSVFSKAQIEQLPSPDDPKQALIQFLEAVGVTYRTLQTFSDKSAMVTKSLEYLGEVLKYIKPYLGKKVSSAGLQLTYGIMGILVKSWAHIFATSKAQKLLFRIIDCLLLPHTVLQQDKELPGPMLTAIQKTLPLYLQGICIVCCQSQNPNAYLNQLLRNVIEQYIGRFLPTSPCVSDLGQHPVLLALRNPASVPSMTPLRKHTVHAIRKSYLEFKGSSPPPRLASVLAFVLQLFKDTEMGACDLELLLPGILKCLVLVNEPQVKKLATENLQCMVQTCQVGSEGGPATQLTSLFRQFIQDYGMQYSYQVYSILETVATLNQHVVIQLIPTLTQSLKDSELKWGLGRNIAQREAYSRLLSGLGQVGQGEKQRLEK", "length": 1238 }, "evidence": [ { "id": "E1BGH8", "url": "https://omabrowser.org/oma/group/E1BGH8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B3DIY3-1", "protein_name": "Protein MMS22-like", "gene_name": "mms22l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESEFSQSLTPPVSPSALNHYGESAPSRPPCFTCAYEAGREDTGRLSSNGYISRGALKRLLLKLDPAPADFGGDTVDIFDFPWVTETALVESTKLLFGLFRQKVLKLETLVQSSSHDFGQASSLHYEAEELRQQCVLFLSYIKVFIYRFLEPSQSLDEGPVHPFKDAEAQLPSVLVEELFSITLLIGRIGNLPANVQSAFTIQHQGKLFPPSWQLLHLHLDIHWSVLEILHLLEQRMMGQVVYAHQFVNLTGETLTNISLFEDQVNNLFCDLIGLAMNKYNKVRPTETLNTHHYHCLCTKELWILLIHLLEHRSKSIHTQSFWSYINALLQTVLKGTTSGDRDPGFPVHCKDPEGFTWWLLTHLAQIGMHNRNGTAQQEKQLEDNWSFVIGLLKSICDPKKAAQEEQIRVVVHCCLSLSLMWGPNVSAVTTFWEYYSKNLNSSFTVPWLGVSGLGSICRTPLCLLQQAKSCCSPAPVGSSSHTQLYRTANSFHIFLRILALHLSQEHAGGAPWRQIKGRLYSKFHQRRMMELSDMGLLHFLLLFLVLAQCAELEDVASRACDLLAMLPTNSTPLALRALQWRGQLALVLLYLEKGLDVGALAEQLAVYFSQAAREFYLKTTEPSRKLALWAPLSSYLEGVSEVFETSPNLTLSEERLLNEGFGLLLPACRQSELSSALGFLQTVLAQLRRVHQRCGQPSHSVDSPSWAPLPSVAKERHQAVAAALWSHFFPFLCSMRLSQTPPPQLADAAAGFTLLALDMPGSAPQNLQPHPIQSIMQSFGWDEMLHPLLVTHYLNHLLQNGELVSWVSSGQGSGSAQALCVRAWIRCVLQQYLHKSPDAPDARAGRNLDEQLAELTRQVFRLPEVEFVLQRAGLQSAAVKDPKAAMAVFLKAVGRSYCELQLLSERSSAVSRALEYVGDILKYIKPYLQNKSREGLQLAYWTIGCLVKHWSHLLATSKAQQLLFRIVDVLLLPHALLQQDTAAHTQMLSALKDSLPMFLQGLSVAVSVSHSQGAYLKQQQHSVISQYLSRFLPATPSTGAVVNHPVLLAACESTPSPQGERLRKSILHVLRENFLQFKGLAPPPRLAAVLCFLLELLKRNSDRDPALLTIPLPSVLRCLMLVNEPQVKRLSSEVTQLIVERCTAAVGEQPCEHTTAILRAFVDENEGVYDQQVYNVLEVVAVLHPFTVAALIPFLTLSLRKTECKRGLGKNTSLRNGYRRLLALLGDSGQAEMISLEED", "length": 1240 }, "evidence": [ { "id": "E1BGH8", "url": "https://omabrowser.org/oma/group/E1BGH8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZS39-1", "protein_name": "Protein MMS22-like", "gene_name": "Mms22l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGGSAASTFLTDSLELELGTEWCKPPCFSCAFDSRDGKFSGESYLASGALKRLILNLDPLPTNFEEDTVELFGIQWVTETALVHSCRELFHLFRQQIFNLESLLQVNCDFGKIAALHAKADSIRQQCVVFLHYLKVFIFRWLKVQEAESHSLLVHPYEVLEAQLPSMLVDELHGLLLYIGHLAELPSVTLGAFVNQNQIKLFPPSWHLLHLFLDTHWLVLEILHMLGEKLKQVVYGRQFISQAGDSLTNVSLFEEHCEHLFCDLICLSLNRYDKVMPSEALMISHYPCSCVKELWVLLIHLLDHRSKWSAAESFWNWLNKLLRTLFEKSSEQRRPVSITHAKDPLGFSWWISVHVASLFQIDRHGVLDEMRQMESNWSFVEELLKQSVTVQDGILEEQLRMHLHCCLTLCDFWEPNLSVVTILWEYYCKNLNSSFSISWLPLKGLTNIIKSPLSMLTLVKNCYCDKQDPDLYKSSSSYIIFLCILAKVVKKAMKNSGSHPWKQVKGRIYSKFHQRRMEELTEVGLQNFFCLFLLLAAVAEIEDVASHVLDLLRFLRPASMSSHGTLVWKGQMAFLLMYAQKNLDIGVWAEKLSCEFQEKAKEFLVSKHDEMVQRHDLWTQLSIYIDGVQEVFETSSCLCPSHEHLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSIRQQLCQELQRENVDRILQSSLSAKERPLAAVAGALWRHFFSFLKSQRMTQVVPLSQLADAAADFTLLAVDMPNTAPPDLQPQPVISIMQLFGWDDIIWPQVVARYLSHLLQNSTVCEALSQSSCVSFQSLTIRSWVRCVLQMYVKHLSEPDLLIDMNPDQVMEKEYMEQLTEMTRLLFTLSEVKNIFSKAQIEYLPNPEDPKQALIQFLEAVGVTYRTLQTFSDKSAMVTKSLEYLGEILKYIKPYLGKKVSSAGLQLTYGIMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHTVLQQDKELPVPMLTAIQKTLPLYLQGICAVCCQSQNPNAYLNQLLRNVIEQYIGRFLPASPSVSDLGQHPVLLALRSPASVPWMMPLRKHIVHAIRKSYLEFKGSSPPPRLASVLAFILQLFKDTTLGVCDLELLLPGVLKCLVLVNEPQVKRLATENLQCMVKTCQVGSEGGPATQLTSLFRQFIQDYGMQYSYQVYSILETVAALSQHIGIQLIPTLTQSLKDSELKWGLGKNIAQREAYSKLLSRLGQAGQDEKQRLESDKL", "length": 1240 }, "evidence": [ { "id": "E1BGH8", "url": "https://omabrowser.org/oma/group/E1BGH8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O46089-1", "protein_name": "Protein MMS22-like", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYDLFQSDDEEILATFIQATQKQETLSAQIDVDDSEEDLVDGLHLPEFNCSGRDTLKSQLCEGGFLGNGYAQLDPPRSRLDYLCFDFAPAQLAVGAVRNYLYGEACKNVQKLLTVVMGQQHLQATAASMNSGWYRVRQQVTHFYHLMLLLRGNELLPSHFLDGFRQLLNDQLDADTWKVLYFAEHNKGNDCQAPAYHLYHGVLEWRFLDLHILYASGNDQAFLGQLERTLDDLIVCAGHHYRSKHRSELIHSSPFMCRCNKELWLLLKRLIPKWLGERELDFWTLFHKAMQRHKSLHFQGESNAISLAYHELYSWLRLGLARLDEYNSEGWYQPDHSPLTAAPESFQTASLLKQFLASQPDEQQRRVYLIQLSPLQLQLGKPDTDVLCQLWEYFHRSLNCNFSVGTELDQLPLTCSNGSAYVDRYNKLLSKSHIEDLNLSSFTMYAWMLGKTLKLLPSQGRSNQRQKLLGRIFSKFSAAKLLALNEPGIHHVIELFLCLLLCHEDLSELAPKLREMLLCLALEKLPPVRRILVAKGHMALLLLHAQHRLSMDDYVSKLLNQLATIRNDAEVGAIYVGSLQAIFNLADDFNRGEQQLLGPWLAHYVEKCGQASQDRVWQTLHNLILRLSERRAVAGNASGIKEALQQHIMPLVRTQYVSSHSSWLPKLAANFIALENNGDKLLLGFLQGPEPINMAASAQLLLQVLEDGGRPASSTILQVWVKSLVLLNAQHESVLALMPHVTQLEEFRLLAIDPTSLEGGREPLCAFFGALGRRAQQEEAAAHVRMQLSHKLHAYVNHFELWLPPDRSRSELGSRFYSFLAIVIYNCSTLAYVRSKPSCFFHLAMVRFLLTTQLQAGVPPEGRLPQVVHKIFPVLLQGIGRLPYRTDAYVAKTLEQLVQHWTPHFSFSSNAKLVARPYATLLQADVDGELAQFVLQLLVTQFLVVQRRRAGQHAGLVITIMQQLIESTGKEQEEQLLTVLRGVHIPLLEHVMFVDEVDLSRNQVFGLYKVLISHDAYKRSQAVRDMCSNHLRSLAEKHLAHCTYFYFQMLINLAELAPDLVAPILSFIREQAEQVELKRGAGEDVGIRKCLQRLQKVLSRV", "length": 1102 }, "evidence": [ { "id": "E1BGH8", "url": "https://omabrowser.org/oma/group/E1BGH8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6ZRQ5-1", "protein_name": "Protein MMS22-like", "gene_name": "MMS22L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENCSAASTFLTDSLELELGTEWCKPPYFSCAVDNRGGGKHFSGESYLCSGALKRLILNLDPLPTNFEEDTLEIFGIQWVTETALVNSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLHCKADNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDELHGLLLYIGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQFMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLLIHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQGVILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSSYTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLDLLNFLKPAFVTSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLENDNT", "length": 1243 }, "evidence": [ { "id": "E1BGH8", "url": "https://omabrowser.org/oma/group/E1BGH8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" }, { "name": "FACT complex", "id": "GO:0035101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035101", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" }, { "name": "MCM complex", "id": "GO:0042555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042555", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "E1BGH8", "url": "https://www.uniprot.org/uniprotkb/E1BGH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGH8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1244, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGH8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGH8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 251, "end_pos": 253 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"MNSYRHSGCEGRPLGGGLGALGRDPLDPEAGHPPQPPNGPGIQVVVAKSEPAQPSPGSPRGQPQDQEEEEDEEEDEAVRQRGSGKPPSVGHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKLFMVDNGADDWRIAMTCERVFLISLELAVCAIHPVPGHYRFTWTARLAFTYTPSAAEADVDVLLSVPMFLRLYLLGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQLRSVKIEQGKLNDQTNTLADLAKTQNVMYDLMSELHAQHEELEARLAALESRLDALGTSLQALPGLIAQAIRPPPPTLPPWPGSGPLDQVARSPPHWWPPVAPSDCG", "length": 508, "header": "tr|A0AAA9RT13-1|E1BGY2_BOVIN Computationally mapped isoform of Potassium calcium-activated channel subfamily N member 1 OS=Bos taurus OX=9913 GN=KCNN1 PE=4 SV=1 CANONICAL=E1BGY2-1" }, "locus": { "chromosome": "7", "start_pos": 5208126, "end_pos": 5185460, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096500.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096500.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074887.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074887.1" } ] } }, { "isoform_ac": "A0AAA9TQB0-1", "url": "https://www.uniprot.org/uniprotkb/E1BGY2/entry#A0AAA9TQB0-1", "sequence": { "sequence": "MRALPLPPAPPPRGLAPARCCPPRPQPRPRPRPRPRPGGPWPRGSLSLPASSARPSRVPQVSAGARLLSHARPQAAGSKPNASTHIVMNSYRHSGCEGRPLGGGLGALGRDPLDPEAGHPPQPPNGPGIQVVVAKSEPAQPSPGSPRGQPQDQEEEEDEEEDEAVRQRGSGKPPSVGHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESLYSFALKCLISLSTVILLGLVILYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIHPVPGHYRFTWTARLAFTYTPSAAEADVDVLLSVPMFLRLYLLGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQLRSVKIEQGKLNDQTNTLADLAKTQNVMYDLMSELHAQHEELEARLAALESRLDALGTSLQALPGLIAQAIRPPPPTLPPWPGSGPLDQVARSPPHWWPPVAPSDCG", "length": 627, "header": "tr|A0AAA9TQB0-1|E1BGY2_BOVIN Computationally mapped isoform of Potassium calcium-activated channel subfamily N member 1 OS=Bos taurus OX=9913 GN=KCNN1 PE=4 SV=1 CANONICAL=E1BGY2-1" }, "locus": { "chromosome": "7", "start_pos": 5214434, "end_pos": 5185460, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105932.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105932.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099210.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099210.1" } ] } }, { "isoform_ac": "E1BGY2-1", "url": "https://www.uniprot.org/uniprotkb/E1BGY2/entry#E1BGY2-1", "sequence": { "sequence": "MNSYRHSGCEGRPLGGGLGALGRDPLDPEAGHPPQPPNGPGIQVVVAKSEPAQPSPGSPRGQPQDQEEEEDEEEDEAVRQRGSGKPPSVGHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESLYSFALKCLISLSTVILLGLVILYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIHPVPGHYRFTWTARLAFTYTPSAAEADVDVLLSVPMFLRLYLLGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERENMYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQAQKLRSVKIEQGKLNDQTNTLADLAKTQNVMYDLMSELHAQHEELEARLAALESRLDALGTSLQALPGLIAQAIRPPPPTLPPWPGSGPLDQVARSPPHWWPPVAPSDCG", "length": 546, "header": "tr|E1BGY2-1|E1BGY2_BOVIN Isoform 1 of Potassium calcium-activated channel subfamily N member 1 OS=Bos taurus OX=9913 GN=KCNN1 PE=4 SV=4 CANONICAL=E1BGY2-1" }, "locus": { "chromosome": "7", "start_pos": 5208126, "end_pos": 5185460, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011376.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011376.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011376.7", "url": "https://www.ensembl.org/id/ENSBTAP00000011376.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1296052", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296052", "resource": "Reactome", "description": "Ca2+ activated K+ channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "E1BGY2", "url": "https://www.uniprot.org/uniprotkb/E1BGY2" } ], "pmid": "" }, { "name": "small conductance calcium-activated potassium channel activity", "id": "GO:0016286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016286", "evidence": [ { "database": "UniProtKB", "id": "E1BGY2", "url": "https://www.uniprot.org/uniprotkb/E1BGY2" } ], "pmid": "" }, { "name": "inward rectifier potassium channel activity", "id": "GO:0005242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005242", "evidence": [ { "database": "UniProtKB", "id": "E1BGY2", "url": "https://www.uniprot.org/uniprotkb/E1BGY2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BGY2", "url": "https://www.uniprot.org/uniprotkb/E1BGY2" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "E1BGY2", "url": "https://www.uniprot.org/uniprotkb/E1BGY2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BGY2", "url": "https://www.uniprot.org/uniprotkb/E1BGY2" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "E1BGY2", "url": "https://www.uniprot.org/uniprotkb/E1BGY2" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "E1BGY2", "url": "https://www.uniprot.org/uniprotkb/E1BGY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "E1BGY2", "url": "https://www.uniprot.org/uniprotkb/E1BGY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], 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"monoisotopic_mass": 40860.0 }, "refseq": { "ac": "XP_010810461", "name": "ribonucleoside-diphosphate reductase subunit M2 B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810461" }, "gene_names": [ { "name": "RRM2B", "type": "recommended", "evidence": [ { "id": "E1BFQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8" } ] }, { "name": "RRM2B", "type": "synonym", "evidence": [ { "id": "XP_010810461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810461" } ] } ], "protein_names": [ { "name": "ribonucleoside-diphosphate reductase", "type": "recommended", "evidence": [ { "id": "E1BFQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8/entry#names_and_taxonomy" } ] }, { "name": "1.17.4.1", "type": "synonym", "evidence": [ { "id": "E1BFQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8/entry#names_and_taxonomy" } ] }, { "name": "ribonucleoside-diphosphate reductase subunit M2 B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010810461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810461" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFQ8", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RRM2B", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8", "locus": { "chromosome": "14", "start_pos": 62171350, "end_pos": 62133683, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021208", "url": "https://www.ensembl.org/id/ENSBTAG00000021208" } ] } } ], "crossref": [ { "id": "E1BFQ8", "url": "https://alphafold.ebi.ac.uk/entry/E1BFQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021208", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021208", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01049", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01049", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "528960", "url": "https://www.ncbi.nlm.nih.gov/gene/528960", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:528960", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528960", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LEPMFLG", "url": "https://omabrowser.org/oma/group/LEPMFLG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFQ8", "url": "https://www.orthodb.org/?gene=E1BFQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23409:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23409:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00268", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00268", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-499943", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-499943", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010810461", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810461", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RXC3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXC3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SK67", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SK67-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTV8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFQ8", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFQ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDPERPEAARPQPEERLSSDTNENEAKSDEEPLLRKSSRRFVIFPIQYPDIWKMYKKAQASFWTAEEVDLSKDLPHWNKLKSEEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVNAVEIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLTELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF", "length": 351, "header": "tr|E1BFQ8-1|E1BFQ8_BOVIN Isoform 1 of ribonucleoside-diphosphate reductase OS=Bos taurus OX=9913 GN=RRM2B PE=3 SV=1 CANONICAL=E1BFQ8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RXC3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8/entry#A0AAA9RXC3-1", "sequence": { "sequence": "MGDPERPEAARPQPEERLSSDTNENEAKSDEEPLLRKSSRRFVIFPIQYPDIWKMYKKAQASFWTAEEVDLSKDLPHWNKLKSEEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVNAVEIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLTELGFSKIIGEANGNSLQYSCLENPMDREAWWATVHRITKSWPRLSTHTPQVIADELVHLKHL", "length": 357, "header": "tr|A0AAA9RXC3-1|E1BFQ8_BOVIN Computationally mapped isoform of ribonucleoside-diphosphate reductase OS=Bos taurus OX=9913 GN=RRM2B PE=3 SV=1 CANONICAL=E1BFQ8-1" }, "locus": { "chromosome": "14", "start_pos": 62160781, "end_pos": 62134044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128849.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128849.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078157.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078157.1" } ] } }, { "isoform_ac": "A0AAA9SK67-1", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8/entry#A0AAA9SK67-1", "sequence": { "sequence": "MGDPERPEAARPQPEERLSSDTNENEAKSDEEPLLRKSSRRFVIFPIQYPDIWKMYKKAQASFWTAEEVDLSKDLPHWNKLKSEEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVNAVEIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLTELGFSKELRVWNLHLGGPREPGV", "length": 318, "header": "tr|A0AAA9SK67-1|E1BFQ8_BOVIN Computationally mapped isoform of ribonucleoside-diphosphate reductase OS=Bos taurus OX=9913 GN=RRM2B PE=3 SV=1 CANONICAL=E1BFQ8-1" }, "locus": { "chromosome": "14", "start_pos": 62170942, "end_pos": 62134044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129270.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129270.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084268.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084268.1" } ] } }, { "isoform_ac": "A0AAA9TTV8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8/entry#A0AAA9TTV8-1", "sequence": { "sequence": "MLLWLRQERLSSDTNENEAKSDEEPLLRKSSRRFVIFPIQYPDIWKMYKKAQASFWTAEEVDLSKDLPHWNKLKSEEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVNAVEIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLTELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF", "length": 343, "header": "tr|A0AAA9TTV8-1|E1BFQ8_BOVIN Computationally mapped isoform of ribonucleoside-diphosphate reductase OS=Bos taurus OX=9913 GN=RRM2B PE=3 SV=2 CANONICAL=E1BFQ8-1" }, "locus": { "chromosome": "14", "start_pos": 62164908, "end_pos": 62133730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087532.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087532.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102054.2", "url": "https://www.ensembl.org/id/ENSBTAP00000102054.2" } ] } }, { "isoform_ac": "E1BFQ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8/entry#E1BFQ8-1", "sequence": { "sequence": "MGDPERPEAARPQPEERLSSDTNENEAKSDEEPLLRKSSRRFVIFPIQYPDIWKMYKKAQASFWTAEEVDLSKDLPHWNKLKSEEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVNAVEIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLTELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF", "length": 351, "header": "tr|E1BFQ8-1|E1BFQ8_BOVIN Isoform 1 of ribonucleoside-diphosphate reductase OS=Bos taurus OX=9913 GN=RRM2B PE=3 SV=1 CANONICAL=E1BFQ8-1" }, "locus": { "chromosome": "14", "start_pos": 62164908, "end_pos": 62134044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028260.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028260.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028260.4", "url": "https://www.ensembl.org/id/ENSBTAP00000028260.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:528960", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528960", "resource": "KEGG Pathway" }, { "id": "R-BTA-499943", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-499943", "resource": "Reactome", "description": "Interconversion of nucleotide di- and triphosphates" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YJX1-1", "protein_name": "ribonucleoside-diphosphate reductase", "gene_name": "RRM2B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTHASTGTGARGLASLETRKRKQRNCGNYSLLQKSLLSSSPSAAENGLKPHEEPLLRKNPRRFVIFPIQHPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHVLAFFAASDGIVNENLVARFSQEVQIPEARCFYGFQILIENVHSEMYSLLIDTYIKDPEKRDFLFNAIETMPCVKKKADWALKWIEDRESTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFHYLVNRPSEERVREIIVNAVEIEQEFLTEALPVGLIGMNCTLMKQYIEFVADRLLMELGFSKVFHAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETMDNVFTLDADF", "length": 372 }, "evidence": [ { "id": "E1BFQ8", "url": "https://omabrowser.org/oma/group/E1BFQ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ADQ1-1", "protein_name": "ribonucleoside-diphosphate reductase", "gene_name": "Rrm2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDPERPEAARPEEGEQLCPETKENEVRSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKSEEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVMEIIVDAVKIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF", "length": 351 }, "evidence": [ { "id": "E1BFQ8", "url": "https://omabrowser.org/oma/group/E1BFQ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P50651-1", "protein_name": "Ribonucleoside-diphosphate reductase small chain A", "gene_name": "RNR2A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGSLKEGQGRDMEEGESEEPLLMAQNQRFTMFPIRYKSIWEMYKKAEASFWTAEEVDLSTDVQQWEALTDSEKHFISHILAFFAASDGIVLENLAARFLNDVQVPEARAFYGFQIAMENIHSEMYSLLLETFIKDSKEKDRLFNAIETIPCISKKAKWCLDWIQSPMSFAVRLVAFACVEGIFFSGSFCAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLLYSLLQKQLPLEKVYQIVHEAVEIETEFVCKALPCDLIGMNSNLMSQYIQFVADRLLVTLGCERTYKAENPFDWMEFISLQGKTNFFEKRVGEYQKASVMSNLQNGNQNYEFTTEEDF", "length": 341 }, "evidence": [ { "id": "E1BFQ8", "url": "https://omabrowser.org/oma/group/E1BFQ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6PEE3-1", "protein_name": "Ribonucleoside-diphosphate reductase subunit M2 B", "gene_name": "Rrm2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDPERPEAARPEKGEQLCSETEENVVRSNEEPLLRKSSRRFVIFPIQYPDIWRMYKQAQASFWTAEEVDLSKDLPHWNKLKSDEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEDRVREIIADAVQIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF", "length": 351 }, "evidence": [ { "id": "E1BFQ8", "url": "https://omabrowser.org/oma/group/E1BFQ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7LG56-1", "protein_name": "Ribonucleoside-diphosphate reductase subunit M2 B", "gene_name": "RRM2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MNSCTSNTPTVITGYQNGHKDVDPNSVEDEPLLRENPKRFVIFPIQYPDIWKMYKQAQASFWTVEEVDLSKDLTHWDGLKSEEKHFISHVLAFFAASDGIVNENLVQRFSQEVQLPEARSFYGFQILIENVHSEMYSMLINTYIRDLKERDYLFNAVQTMPCVRRKADWALQWISDTNSTFGERLVAFAAVEGIFFSGSFAAIYWLKKRGLMPGLTYSNELISRDEGLHCNFACLIYSYLVKKPSVDRVNDIIAKAVSIEQEFLTEALPVNLIGMNCSLMKQYIEFVADRLLTDLGLPKAYCSENPFDFMESISLEGKTNFFEKRVAEYQRLGVMSNVKDCEFTLDADF", "length": 349 }, "evidence": [ { "id": "E1BFQ8", "url": "https://omabrowser.org/oma/group/E1BFQ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BFQ8", "url": "https://www.uniprot.org/uniprotkb/E1BFQ8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MSF1-1", "E1BFQ8-1" ], "evidence": [ { "id": "R-BTA-111804", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111804" } ] }, { "id": "R-BTA-8866405", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BL29-1", "uniprot_ac": "E1BL29", "uniprot_id": "E1BL29_BOVIN", "mass": { "chemical_mass": 52931.0, "monoisotopic_mass": 52931.0 }, "refseq": { "ac": "NP_001290550", "name": "bleomycin hydrolase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290550" }, "gene_names": [ { "name": "BLMH", "type": "recommended", "evidence": [ { "id": "E1BL29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ] }, { "name": "BLMH", "type": "synonym", "evidence": [ { "id": "NP_001290550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290550" } ] } ], "protein_names": [ { "name": "Bleomycin hydrolase", "type": "recommended", "evidence": [ { "id": "E1BL29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL29/entry#names_and_taxonomy" } ] }, { "name": "3.4.22.40", "type": "synonym", "evidence": [ { "id": "E1BL29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL29/entry#names_and_taxonomy" } ] }, { "name": "bleomycin hydrolase", "type": "synonym", "evidence": [ { "id": "NP_001290550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290550" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BLMH", "url": "https://www.uniprot.org/uniprotkb/E1BL29", "locus": { "chromosome": "19", "start_pos": 21333634, "end_pos": 21375948, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021370", "url": "https://www.ensembl.org/id/ENSBTAG00000021370" } ] } } ], "crossref": [ { "id": "E1BL29", "url": "https://alphafold.ebi.ac.uk/entry/E1BL29", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021370", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021370", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00585", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00585", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "504483", "url": "https://www.ncbi.nlm.nih.gov/gene/504483", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504483", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504483", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QSYTFFW", "url": "https://omabrowser.org/oma/group/QSYTFFW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BL29", "url": "https://www.orthodb.org/?gene=E1BL29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10363:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10363:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03051", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03051", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001290550", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290550", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RZG4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZG4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1Z8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TL10", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TL10-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL29-1", "url": "https://www.uniprot.org/uniprotkb/E1BL29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGAGIPAGLNSEKVAALLQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQGTQHVFQHAVHQEGKPVTNQKSSGRCWIFSCLNVMRLPFMRRFNIEEFEFSQSYLFFWDKVERCYFFLNAFVDTAQKKEPEDGRLVQYLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPETYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKEEISATQDSMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLKFYRQHVKPLFNMEDKICLVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPVDFLKKMVAASIKDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSMKNMNKAERLTFGESLMTHAMTFTAVSEKDDQEGGFIKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDKKHVPEEVLAVLEQEPIVLPAWDPMGALAK", "length": 459, "header": "tr|E1BL29-1|E1BL29_BOVIN Isoform 1 of Bleomycin hydrolase OS=Bos taurus OX=9913 GN=BLMH PE=3 SV=1 CANONICAL=E1BL29-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RZG4-1", "url": "https://www.uniprot.org/uniprotkb/E1BL29/entry#A0AAA9RZG4-1", "sequence": { "sequence": "MNGAGIPAGLNSEKVAALLQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQGTQHVFQHAVHQEGKPVTNQKSSGRCWIFSCLNVMRLPFMRRFNIEEFEFSQSYLFFWDKVERCYFFLNAFVDTAQKKEPEDGRLVQYLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPETYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKEEISATQDSMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLKFYRQHVKPLFNMEDKICLVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPVDFLKKMVAASIKDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSMKNMNKAERLTFGESLMTHAMTFTAVSEKDDQEGGFIKWRVENSWGEDHGHKAFLPAAWEA", "length": 418, "header": "tr|A0AAA9RZG4-1|E1BL29_BOVIN Computationally mapped isoform of Bleomycin hydrolase OS=Bos taurus OX=9913 GN=BLMH PE=3 SV=1 CANONICAL=E1BL29-1" }, "locus": { "chromosome": "19", "start_pos": 21374730, "end_pos": 21350583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103128.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103128.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078047.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078047.1" } ] } }, { "isoform_ac": "A0AAA9S1Z8-1", "url": "https://www.uniprot.org/uniprotkb/E1BL29/entry#A0AAA9S1Z8-1", "sequence": { "sequence": "MSNWMLVEPTVGEGIPAGLNSEKVAALLQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQGTQHVFQHAVHQEGKPVTNQKSSGRCWIFSCLNVMRLPFMRRFNIEEFEFSQSYLFFWDKVERCYFFLNAFVDTAQKKEPEDGRLVQYLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPETYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKEEISATQDSMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLKFYRQHVKPLFNMEDKICLVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPVDFLKKMVAASIKDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSMKNMNKAERLTFGESLMTHAMTFTAVSEKDDQEGGFIKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDKKHVPEEVLAVLEQEPIVLPAWDPMGALAK", "length": 468, "header": "tr|A0AAA9S1Z8-1|E1BL29_BOVIN Computationally mapped isoform of Bleomycin hydrolase OS=Bos taurus OX=9913 GN=BLMH PE=3 SV=1 CANONICAL=E1BL29-1" }, "locus": { "chromosome": "19", "start_pos": 21375749, "end_pos": 21334452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122776.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122776.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079916.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079916.1" } ] } }, { "isoform_ac": "A0AAA9TL10-1", "url": "https://www.uniprot.org/uniprotkb/E1BL29/entry#A0AAA9TL10-1", "sequence": { "sequence": "MLKLKLQYSCHLIRRADSLKETMMPGKIEGRCWIFSCLNVMRLPFMRRFNIEEFEFSQSYLFFWDKVERCYFFLNAFVDTAQKKEPEDGRLVQYLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPETYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKEEISATQDSMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLKFYRQHVKPLFNMEDKICLVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPVDFLKKMVAASIKDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSMKNMNKAERLTFGESLMTHAMTFTAVSEKDDQEGGFIKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDKKHVPEEVLAVLEQEPIVLPAWDPMGALAK", "length": 414, "header": "tr|A0AAA9TL10-1|E1BL29_BOVIN Computationally mapped isoform of Bleomycin hydrolase OS=Bos taurus OX=9913 GN=BLMH PE=3 SV=1 CANONICAL=E1BL29-1" }, "locus": { "chromosome": "19", "start_pos": 21371341, "end_pos": 21334452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135393.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135393.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096968.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096968.1" } ] } }, { "isoform_ac": "E1BL29-1", "url": "https://www.uniprot.org/uniprotkb/E1BL29/entry#E1BL29-1", "sequence": { "sequence": "MNGAGIPAGLNSEKVAALLQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQGTQHVFQHAVHQEGKPVTNQKSSGRCWIFSCLNVMRLPFMRRFNIEEFEFSQSYLFFWDKVERCYFFLNAFVDTAQKKEPEDGRLVQYLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPETYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKEEISATQDSMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLKFYRQHVKPLFNMEDKICLVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPVDFLKKMVAASIKDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSMKNMNKAERLTFGESLMTHAMTFTAVSEKDDQEGGFIKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDKKHVPEEVLAVLEQEPIVLPAWDPMGALAK", "length": 459, "header": "tr|E1BL29-1|E1BL29_BOVIN Isoform 1 of Bleomycin hydrolase OS=Bos taurus OX=9913 GN=BLMH PE=3 SV=1 CANONICAL=E1BL29-1" }, "locus": { "chromosome": "19", "start_pos": 21374730, "end_pos": 21334452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028490.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028490.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028490.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028490.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:504483", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504483", "resource": "KEGG Pathway" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AEU4-1", "protein_name": "Bleomycin hydrolase", "gene_name": "BLMH", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNAHGLSTEKAAAFTRRLRAEPQFLLAQNVATCSDPLEVCLQRQVVQDTIQVFQHAVPAEGKPVTNQKNSGRCWIFSCLNAMRLPFMKKYNIEEFEFSQSYLFFWDKVERCYYFLNAFVETAQKKEPIDGRLVQFLLTNPTNDGGQWDMLVNIVEKYGVVPKKYFPESHTTEATRRMNEILNHKMREYCLRLRNMVGTGTNKEELCAAMDTMIEEVFRIVSTCLGNPPETFCWEFRDKEKNYHKFGPMTPVQFYNEHVKPYFNMEDKVCLVNDPRPQNPYCQLYTVEYLGNMAGGRKTLYNNQPIEVLKKLAATSIKDGEAVWFGCDVAKHFYSKLGINDLNIFNHELVFGVSVKNMNKAERLIFGDSLMTHAMVLTAVSEKDGQEDCYEKWRVENSWGEDRGNKGYLIMTDDWFSEYVYEVVVDKKYVPEDVLAVMEQEPIVLPAWDPMGALAK", "length": 455 }, "evidence": [ { "id": "E1BL29", "url": "https://omabrowser.org/oma/group/E1BL29/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P70645-1", "protein_name": "Bleomycin hydrolase", "gene_name": "Blmh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNAGLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQGAQHVFQHVVPQEGKPVTNQKSSGRCWIFSCLNVMRLPFMKKFNIEEFEFSQSYLFFWDKVERCYFFLNAFVDTAQKKEPEDGRLVQYLLMNPTNDGGQWDMLVNIVEKYGVVPKKCFPESHTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISSTQDAMMEEIFRVVCICLGNPPETFTWEYRDKDKNYHKVGPITPLQFYKEHVKPLFNMEDKICFVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPIDFLKKMVAASIRDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSLKNMNKAERLAFGESLMTHAMTFTAVSEKDDQEGAFVKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDKKHVPEEVLAVLEQEPIVLPAWDPMGALA", "length": 454 }, "evidence": [ { "id": "E1BL29", "url": "https://omabrowser.org/oma/group/E1BL29/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13867-1", "protein_name": "Bleomycin hydrolase", "gene_name": "BLMH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSSGLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQRAQHVFQHAVPQEGKPITNQKSSGRCWIFSCLNVMRLPFMKKLNIEEFEFSQSYLFFWDKVERCYFFLSAFVDTAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLEFYREHVKPLFNMEDKICLVNDPRPQHKYNKLYTVEYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNMNKAERLTFGESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDRKHVPEEVLAVLEQEPIILPAWDPMGALAE", "length": 455 }, "evidence": [ { "id": "E1BL29", "url": "https://omabrowser.org/oma/group/E1BL29/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R016-1", "protein_name": "Bleomycin hydrolase", "gene_name": "Blmh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNNAGLNSEKVSALIQKLNSDPQFVLAQNVGTTHDLLDICLRRATVQGAQHVFQHVVPQEGKPVTNQKSSGRCWIFSCLNVMRLPFMKKFNIEEFEFSQSYLFFWDKVERCYFFLNAFVDTAQKKEPEDGRLVQYLLMNPTNDGGQWDMLVNIVEKYGVVPKKCFPESHTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISSTQDAMMEEIFRVVCICLGNPPETFTWEYRDKDKNYHKIGPITPLQFYKEHVKPLFNMEDKICFVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSLKNMNKAERLAFGESLMTHAMTFTAVSEKDNQEGTFVKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDKKHVPEEVLAVLEQEPIVLPAWDPMGALAE", "length": 455 }, "evidence": [ { "id": "E1BL29", "url": "https://omabrowser.org/oma/group/E1BL29/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X2JEJ0-1", "protein_name": "Bleomycin hydrolase", "gene_name": "Dmel\\CG1440", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFWAVRRSVTQIKINSPKLSQNPNTYRNRIPYPQQQQEPAMYYSKESVQTHTISGERCQSHLLAADNNSGSGGGGSGGGGAGNNNSANSGKNSTHRFAETSVITNQLLEKWRKNFYSEPKNLLAQNVCSRVDPFDVCLSRKALETTNHVFNYKVETEGKPVTNQRSSGRCWLFAALNCIRLPFMKNYNLDEFEFSQAFLFYWDKIERCNYFLNNVVKTAQRGEKVDGRLVSFLLLDPTSDGGQWDMLVNLITKHGLMPKKCFPESFSCESSLRMNAILKSKLREYARNLRVLMEKNPTDEEIACKIQEQMAEIYKVVGICLGIPSETFTWEYYDKSKNYQSIGPVSSLEFYERYVKPHFNVEDKVCLVTDPRPTSSYDQAYTVDCLGNVVGGRPVLYNNQSVELLLAVVTKSLKAGEAVWFGCEVSKRFASKQGIEDVDVHDFKLVFDIDIQTTFSKADRLIYGESAMTHAMVFTAVSVDKSGVAQKLRVENSWGEDRGEKGYLVMNADWFREFGFEVVVDKKYVPEDVLRVFDMDPIVLPAWDPMGTLAQ", "length": 551 }, "evidence": [ { "id": "E1BL29", "url": "https://omabrowser.org/oma/group/E1BL29/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ], "pmid": "" }, { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ], "pmid": "" }, { "name": "homocysteine catabolic process", "id": "GO:0043418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043418", "evidence": [ { "database": "UniProtKB", "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ], "pmid": "" }, { "name": "cysteine-type aminopeptidase activity", "id": "GO:0070005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070005", "evidence": [ { "database": "UniProtKB", "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ], "pmid": "" }, { "name": "cysteine-type peptidase activity", "id": "GO:0008234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008234", "evidence": [ { "database": "UniProtKB", "id": "E1BL29", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-983162", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BP91-1", "A0A3Q1M996-1", "E1BL29-1" ], "evidence": [ { "id": "R-BTA-983162", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983162" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M996", "gene_name": "TPP2", "activity": [ { "ec_number": "3.4.14.10", "activity": "Release of an N-terminal tripeptide from a polypeptide.", "evidence": [ { "id": "A0A3Q1M996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M996" } ] }, { "ec_number": "3.4.14.10", "activity": "", "evidence": [ { "id": "A0A3Q1M996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M996" } ] } ] }, { "uniprot_ac": "E1BL29", "gene_name": "BLMH", "activity": [ { "ec_number": "3.4.22.40", "activity": "Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.", "evidence": [ { "id": "E1BL29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ] }, { "ec_number": "3.4.22.40", "activity": "", "evidence": [ { "id": "E1BL29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL29" } ] } ] }, { "uniprot_ac": "E1BP91", "gene_name": "NPEPPS", "activity": [ { "ec_number": "3.4.11.-", "activity": "", "evidence": [ { "id": "E1BP91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP91" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.22.40", "ec_name": "Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.", "evidence": [ { "id": "3.4.22.40", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.22.40" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHV6-1", "uniprot_ac": "E1BHV6", "uniprot_id": "E1BHV6_BOVIN", "mass": { "chemical_mass": 86813.0, "monoisotopic_mass": 86813.0 }, "refseq": { "ac": "XP_024852034", "name": "cilium assembly protein DZIP1L isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852034" }, "gene_names": [ { "name": "DZIP1L", "type": "recommended", "evidence": [ { "id": "E1BHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV6" } ] }, { "name": "DZIP1L", "type": "synonym", "evidence": [ { "id": "XP_024852034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852034" } ] } ], "protein_names": [ { "name": "DAZ interacting zinc finger protein 1 like", "type": "synonym", "evidence": [ { "id": "E1BHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV6/entry#names_and_taxonomy" } ] }, { "name": "cilium assembly protein DZIP1L isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024852034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852034" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHV6", "url": "https://www.uniprot.org/uniprotkb/E1BHV6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DZIP1L", "url": "https://www.uniprot.org/uniprotkb/E1BHV6", "locus": { "chromosome": "1", "start_pos": 131070422, "end_pos": 131015200, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015198", "url": "https://www.ensembl.org/id/ENSBTAG00000015198" } ] } } ], "crossref": [ { "id": "E1BHV6", "url": "https://alphafold.ebi.ac.uk/entry/E1BHV6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015198", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015198", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "512800", "url": "https://www.ncbi.nlm.nih.gov/gene/512800", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SLWDEFK", "url": "https://omabrowser.org/oma/group/SLWDEFK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21502:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21502:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25977", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25977", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024852034", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852034", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MES1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MES1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MES1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MES1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0J4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0J4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZE7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7I2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7I2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHV6", "url": "https://www.uniprot.org/uniprotkb/E1BHV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHV6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSPTTTAQGLSGPLFGAYTLPTFKFQPRRESVDWRRISALDVDRVARELDVATLQENIAGVTFCNLDREVCGRCGQPVDPVLLKVLRLAQLSIEYLLHCQDCLSTSVAQLEARLQASLGQQERGQQELGRQADELKGVREESRRRRKMISALQQLLLQTGAHSYHTCHLCDKTFMNATFLRGHIQRRHTGMVEGGKQRKQEQPVEEVLEELRAKLKWTQGELEAQREAERQRQLQEAEIIRQREAETKKEFDEWKEKERAKLYGEIDKLKKLFWDEFKSVANQNSTLEEKLQALQSHSVMKSNLGSLRDEEPEERLRQAQELWALKEKMEIQKTEWRRKMKALQEEHAAQKRELQEQNERLQATLSQDQRKAAAQAQRQIHALRTQLQEQARLIASQEEMMQALSLRKVEGICEGPKAVDTDEDSSEEELEDSHSGQQKVLEALRRNPTLLKQFRPVLEDTLEEKLESMGIKRDAKGIPAQTLRHLESILRAQREQKARRFSEFLSLREKLIKEATSRVKDRQRDRAPVSQPEGEVPVKSQQSPLVTKEVQPKARTLHVAQPSKPAEPPVTSLQSRSSHSLGLAPGPSPTPRSRASGPPGTPASPGPGLSTPPFSSEEDSEGDAGPRASLQPPRVPSRVGPRPQDDWDWSDTETSEGSAQSPGKGSGGLASSGTLVQSMVRNLEKQLEAPAKKPAGGVSLFSVPSAGPQRAAVPGGKPQLSEDESDLEISSLEDLPQNLNQREKPKPLSRSKLPEKFGTSSWSPSQPRVPGW", "length": 773, "header": "tr|E1BHV6-1|E1BHV6_BOVIN Isoform 1 of DAZ interacting zinc finger protein 1 like OS=Bos taurus OX=9913 GN=DZIP1L PE=3 SV=3 CANONICAL=E1BHV6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MES1-1", "url": "https://www.uniprot.org/uniprotkb/E1BHV6/entry#A0A3Q1MES1-1", "sequence": { "sequence": "MQSPTTTAQGLSGPLFGAYTLPTFKFQPRRESVDWRRISALDVDRVARELDVATLQENIAGVTFCNLDREVCGRCGQPVDPVLLKVLRLAQLSIEYLLHCQDCLSTSVAQLEARLQASLGQQERGQQELGRQADELKGVREESRRRRKMISALQQLLLQTGAHSYHTCHLCDKTFMNATFLRGHIQRRHTGMVEGGKQRKQEQPVEEVLEELRAKLKWTQGELEAQREAERQRQLQEAEIIRQREAETKKEFDEWKEKERAKLYGEIDKLKKLFWDEFKSVANQNSTLEEKLQALQSHSVMKSNLGSLRDEEPEERLRQAQELWALKEKMEIQKTEWRRKMKALQEEHAAQKRELQEQNERLQATLSQDQRKAAAQAQRQIHALRTQLQEQARLIASQEEMMQALSLRKVEGICEGPKAVDTDEDSSEEELEDSHSGQQKVLEALRRNPTLLKQFRPVLEDTLEEKLESMGIKRDAKGIPAQTLRHLESILRAQREQKARRFSEFLSLREKLIKEATSRVKDRQRDRAPVSQPEGEVPATLKAHGNDYLVKSQQSPLVTKEVQPKARTLHVAQPSKPAEPPVTSLQSRSSHSLGLAPGPSPTPRSRASGPPGTPASPGPGLSTPPFSSEEDSEGDAGPRASLQPPRVPSRVGPRPQDDWDWSDTETSEGSAQSPGKGSGGLASSGTLVQSMVRNLEKQLEAPAKKPAGGVSLFSVPSAGPQRAAVPGGKPQLSEDESDLEISSLEDLPQNLNQREKPKPLSRSKLPEKFGTSSWSPSQPRVPGW", "length": 784, "header": "tr|A0A3Q1MES1-1|E1BHV6_BOVIN Computationally mapped isoform of DAZ interacting zinc finger protein 1 like OS=Bos taurus OX=9913 GN=DZIP1L PE=3 SV=2 CANONICAL=E1BHV6-1" }, "locus": { "chromosome": "1", "start_pos": 131069418, "end_pos": 131037131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079710.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079710.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072655.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072655.2" } ] } }, { "isoform_ac": "A0AAA9S0J4-1", "url": "https://www.uniprot.org/uniprotkb/E1BHV6/entry#A0AAA9S0J4-1", "sequence": { "sequence": "MQSPTTTAQGLSGPLFGAYTLPTFKFQPRRESVDWRRISALDVDRVARELDVATLQENIAGVTFCNLDREVCGRCGQPVDPVLLKVLRLAQLSIEYLLHCQDCLSTSVAQLEARLQASLGQQERGQQELGRQADELKGVREESRRRRKMISALQQLLLQTGAHSYHTCHLCDKTFMNATFLRGHIQRRHTGMVEGGKQRKQEQPVEEVLEELRAKLKWTQGELEAQREAERQRQLQEAEIIRQREAETKKEFDEWKEKERAKLYGEIDKLKKLFWDEFKSVANQNSTLEEKLQALQSHSVMKSNLGSLRDEEPEERLRQAQELWALKEKMEIQKTEWRRKMKALQEEHAAQKREMQALSLRKVEGICEGPKAVDTDEDSSEEELEDSHSGQQKVLEALRRNPTLLKQFRPVLEDTLEEKLESMGIKRDAKGIPAQTLRHLESILRAQREQKARRFSEFLSLREKLIKEATSRVKDRQRDRAPVSQPEGEVPVKSQQSPLVTKEVQPKARTLHVAQPSKPAEPPVTSLQSRSSHSLGLAPGPSPTPRSRASGPPGTPASPGPGLSTPPFSSEEDSEGDAGPRASLQPPRVPSRVGPRPQDDWDWSDTETSEGSAQSPGKGSGGLASSGTLVQSMVRNLEKQLEAPAKKPAGGVSLFSVPSAGPQRAAVPGGKPQLSEDESDLEISSLEDLPQNLNQREKPKPLSRSKLPEKFGTSSWSPSQPRVPGW", "length": 726, "header": "tr|A0AAA9S0J4-1|E1BHV6_BOVIN Computationally mapped isoform of DAZ interacting zinc finger protein 1 like OS=Bos taurus OX=9913 GN=DZIP1L PE=3 SV=1 CANONICAL=E1BHV6-1" }, "locus": { "chromosome": "1", "start_pos": 131069418, "end_pos": 131037131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092565.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092565.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079372.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079372.1" } ] } }, { "isoform_ac": "A0AAA9SZE7-1", "url": "https://www.uniprot.org/uniprotkb/E1BHV6/entry#A0AAA9SZE7-1", "sequence": { "sequence": "MQSPTTTAQGLSGPLFGAYTLPTFKFQPRRESVDWRRISALDVDRVARELDVATLQENIAGVTFCNLDREVCGRCGQPVDPVLLKVLRLAQLSIEYLLHCQDCLSTSVAQLEARLQASLGQQERGQQELGRQADELKGVREESRRRRKMISALQQLLLQTGAHSYHTCHLCDKTFMNATFLRGHIQRRHTGMVEGGKQRKQEQPVEEVLEELRAKLKWTQGELEAQREAERQRQLQEAEIIRQREAETKKEFDEWKEKERAKLYGEIDKLKKLFWDEFKSVANQNSTLEEKLQALQSHSVMKSNLGSLRDEEPEERLRQAQELWALKEKMEIQKTEWRRKMKALQEEHAAQKRELQEQNERLQATLSQDQRKAAAQAQRQIHALRTQLQEQARLIASQEEMMQALSLRKVEGICEGPKAVDTDEDSSEEELEDSHSGQQKVLEALRRNPTLLKQFRPVLEDTLEEKLESMGIKRDAKGIPAQTLRHLESILRAQREQKARRFSEFLSLREKLIKEATSRVKDRQRDRAPVSQPEGEVPGRPNLSSLCKGNFQSVVHTSLGVKSQQSPLVTKEVQPKARTLHVAQPSKPAEPPVTSLQSRSSHSLGLAPGPSPTPRSRASGPPGTPASPGPGLSTPPFSSEEDSEGDAGPRASLQPPRVPSRVGPRPQDDWDWSDTETSEGSAQSPGKGSGGLASSGTLVQSMVRNLEKQLEAPAKKPAGGVSLFSVPSAGPQRAAVPGGKPQLSEDESDLEISSLEDLPQNLNQREKPKPLSRSKLPEKFGTSSWSPSQPRVPGW", "length": 795, "header": "tr|A0AAA9SZE7-1|E1BHV6_BOVIN Computationally mapped isoform of DAZ interacting zinc finger protein 1 like OS=Bos taurus OX=9913 GN=DZIP1L PE=3 SV=1 CANONICAL=E1BHV6-1" }, "locus": { "chromosome": "1", "start_pos": 131069418, "end_pos": 131037131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108834.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108834.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091831.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091831.1" } ] } }, { "isoform_ac": "A0AAA9T7I2-1", "url": "https://www.uniprot.org/uniprotkb/E1BHV6/entry#A0AAA9T7I2-1", "sequence": { "sequence": "MQSPTTTAQGLSGPLFGAYTLPTFKFQPRRESVDWRRISALDVDRVARELDVATLQENIAGVTFCNLDREVCGRCGQPVDPVLLKVLRLAQLSIEYLLHCQDCLSTSVAQLEARLQASLGQQERGQQELGRQADELKGVREESRRRRKMISALQQLLLQTGAHSYHTCHLCDKTFMNATFLRGHIQRRHTGMVEGGKQRKQEQPVEEVLEELRAKLKWTQGELEAQREAERQRQLQEAEIIRQREAETKKEFDEWKEKERAKLYGEIDKLKKLFWDEFKSVANQNSTLEEKLQALQSHSVMKSNLGSLRDEEPEERLRQAQELWALKEKMEIQKTEWRRKMKALQEEHAAQKRELQEQNERLQATLSQDQRKAAAQAQRQIHALRTQLQEQARLIASQEEMMQALSLRKVEGICEGPKAVDTDEDSSEEELEDSHSGQQKVLEALRRNPTLLKQFRPVLEDTLEEKLESMGIKRDAKGIPAQTLRHLESILRAQREQKARRFSEFLSLREKLIKEATSRVKDRQRDRAPVSQPEGEVPGRPNLSSLCKGNFQSVVHTSLGATLKAHGNDYLVKSQQSPLVTKEVQPKARTLHVAQPSKPAEPPVTSLQSRSSHSLGLAPGPSPTPRSRASGPPGTPASPGPGLSTPPFSSEEDSEGDAGPRASLQPPRVPSRVGPRPQDDWDWSDTETSEGSAQSPGKGSGGLASSGTLVQSMVRNLEKQLEAPAKKPAGGVSLFSVPSAGPQRAAVPGGKPQLSEDESDLEISSLEDLPQNLNQREKPKPLSRSKLPEKFGTSSWSPSQPRVPGW", "length": 806, "header": "tr|A0AAA9T7I2-1|E1BHV6_BOVIN Computationally mapped isoform of DAZ interacting zinc finger protein 1 like OS=Bos taurus OX=9913 GN=DZIP1L PE=3 SV=1 CANONICAL=E1BHV6-1" }, "locus": { "chromosome": "1", "start_pos": 131069418, "end_pos": 131037131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128659.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128659.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093885.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093885.1" } ] } }, { "isoform_ac": "E1BHV6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHV6/entry#E1BHV6-1", "sequence": { "sequence": "MQSPTTTAQGLSGPLFGAYTLPTFKFQPRRESVDWRRISALDVDRVARELDVATLQENIAGVTFCNLDREVCGRCGQPVDPVLLKVLRLAQLSIEYLLHCQDCLSTSVAQLEARLQASLGQQERGQQELGRQADELKGVREESRRRRKMISALQQLLLQTGAHSYHTCHLCDKTFMNATFLRGHIQRRHTGMVEGGKQRKQEQPVEEVLEELRAKLKWTQGELEAQREAERQRQLQEAEIIRQREAETKKEFDEWKEKERAKLYGEIDKLKKLFWDEFKSVANQNSTLEEKLQALQSHSVMKSNLGSLRDEEPEERLRQAQELWALKEKMEIQKTEWRRKMKALQEEHAAQKRELQEQNERLQATLSQDQRKAAAQAQRQIHALRTQLQEQARLIASQEEMMQALSLRKVEGICEGPKAVDTDEDSSEEELEDSHSGQQKVLEALRRNPTLLKQFRPVLEDTLEEKLESMGIKRDAKGIPAQTLRHLESILRAQREQKARRFSEFLSLREKLIKEATSRVKDRQRDRAPVSQPEGEVPVKSQQSPLVTKEVQPKARTLHVAQPSKPAEPPVTSLQSRSSHSLGLAPGPSPTPRSRASGPPGTPASPGPGLSTPPFSSEEDSEGDAGPRASLQPPRVPSRVGPRPQDDWDWSDTETSEGSAQSPGKGSGGLASSGTLVQSMVRNLEKQLEAPAKKPAGGVSLFSVPSAGPQRAAVPGGKPQLSEDESDLEISSLEDLPQNLNQREKPKPLSRSKLPEKFGTSSWSPSQPRVPGW", "length": 773, "header": "tr|E1BHV6-1|E1BHV6_BOVIN Isoform 1 of DAZ interacting zinc finger protein 1 like OS=Bos taurus OX=9913 GN=DZIP1L PE=3 SV=3 CANONICAL=E1BHV6-1" }, "locus": { "chromosome": "1", "start_pos": 131069418, "end_pos": 131037131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020222.6", "url": "https://www.ensembl.org/id/ENSBTAT00000020222.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020222.5", "url": "https://www.ensembl.org/id/ENSBTAP00000020222.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 591, "start_aa": "Thr", "end_pos": 591, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr591", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 602, "start_aa": "Thr", "end_pos": 602, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr602", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BHV6", "url": "https://www.uniprot.org/uniprotkb/E1BHV6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "E1BHV6", "url": "https://www.uniprot.org/uniprotkb/E1BHV6" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "E1BHV6", "url": "https://www.uniprot.org/uniprotkb/E1BHV6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1BHV6", "url": "https://www.uniprot.org/uniprotkb/E1BHV6" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "E1BHV6", "url": "https://www.uniprot.org/uniprotkb/E1BHV6" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "E1BHV6", "url": "https://www.uniprot.org/uniprotkb/E1BHV6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BHV6", "url": "https://www.uniprot.org/uniprotkb/E1BHV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 166, "end_pos": 194, "start_aa": "His", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 591, 602 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 285, "end_pos": 287 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFW1-1", "uniprot_ac": "E1BFW1", "uniprot_id": "E1BFW1_BOVIN", "mass": { "chemical_mass": 26375.0, "monoisotopic_mass": 26375.0 }, "refseq": { "ac": "NP_001192755", "name": "coiled-coil domain-containing protein 134 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192755" }, "gene_names": [ { "name": "CCDC134", "type": "recommended", "evidence": [ { "id": "E1BFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFW1" } ] }, { "name": "CCDC134", "type": "synonym", "evidence": [ { "id": "NP_001192755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192755" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 134", "type": "synonym", "evidence": [ { "id": "E1BFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFW1/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 134 precursor", "type": "synonym", "evidence": [ { "id": "NP_001192755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192755" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFW1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC134", "url": "https://www.uniprot.org/uniprotkb/E1BFW1", "locus": { "chromosome": "5", "start_pos": 112828967, "end_pos": 112813766, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021173", "url": "https://www.ensembl.org/id/ENSBTAG00000021173" } ] } } ], "crossref": [ { "id": "E1BFW1", "url": "https://alphafold.ebi.ac.uk/entry/E1BFW1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021173", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021173", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "516012", "url": "https://www.ncbi.nlm.nih.gov/gene/516012", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516012", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516012", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GIGFCNQ", "url": "https://omabrowser.org/oma/group/GIGFCNQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFW1", "url": "https://www.orthodb.org/?gene=E1BFW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14735", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14735", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14735:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14735:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192755", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S3N7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3N7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3N7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG81", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG81-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMD3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMD3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFW1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFW1-1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLLQFLTSLSVLLLSGTGVTDTLRTSLDPSLEIYKKMFEVKRREQLLALKNLAQLNDVHQQYKILDVMLKGLFKVLEDSRTVLTAAGVLPDGPFPQDEKLKDAFSQVVENTAFFGDVVLRFPRIVHHYFDHNSNWNLLIRWGISFCNQSGVFDQGPHSPILGLMAQELGISEKHSDFQNPFKVDRTEFISSTDPFQKALREEEKRRKKEEKRKEIRKGPRISRSQSEL", "length": 229, "header": "tr|E1BFW1-1|E1BFW1_BOVIN Isoform 1 of Coiled-coil domain containing 134 OS=Bos taurus OX=9913 GN=CCDC134 PE=4 SV=1 CANONICAL=E1BFW1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S3N7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1/entry#A0AAA9S3N7-1", "sequence": { "sequence": "MDLLQFLTSLSVLLLSGTGVTDTLRTSLDPSLEIYKKMFEVKRREQLLALKNLAQLNDVHQQYKILDVMLKGLFKVLEDSRTVLTAAGVLPDGPFPQDEKLKDAFSQVVENTAFFGDVVLRFPRIVHHYFDHNSNWNLLIRWGISFCNQSGVFDQGPHSPILGLMAQELGISEKHSDFQNPFKVDRTEMLTDCWGRYRRSTVPVEHDHWNQWERDVSRAMGPMRGNLWK", "length": 229, "header": "tr|A0AAA9S3N7-1|E1BFW1_BOVIN Computationally mapped isoform of Coiled-coil domain containing 134 OS=Bos taurus OX=9913 GN=CCDC134 PE=4 SV=1 CANONICAL=E1BFW1-1" }, "locus": { "chromosome": "5", "start_pos": 112823861, "end_pos": 112815386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118045.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118045.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077880.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077880.1" } ] } }, { "isoform_ac": "A0AAA9SG81-1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1/entry#A0AAA9SG81-1", "sequence": { "sequence": "MDLLQFLTSLSVLLLSGTGVTDTLRTSLDPSLEIYKKMFEVKRREQLLALKNLAQLNDVHQQYKILDVMLKGLFKFISSTDPFQKALREEEKRRKKEEKRKEIRKGPRISRSQSEL", "length": 116, "header": "tr|A0AAA9SG81-1|E1BFW1_BOVIN Computationally mapped isoform of Coiled-coil domain containing 134 OS=Bos taurus OX=9913 GN=CCDC134 PE=4 SV=1 CANONICAL=E1BFW1-1" }, "locus": { "chromosome": "5", "start_pos": 112828485, "end_pos": 112815386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087803.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087803.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084377.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084377.1" } ] } }, { "isoform_ac": "A0AAA9TMD3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1/entry#A0AAA9TMD3-1", "sequence": { "sequence": "ESTALLVASRPSSRLLPDSCPPRPPGPLQSLGYGPSSVPDLPVCPAIVWNRSHRHPEDLPGPEPGDLYPLGLEVLEDSRTVLTAAGVLPDGPFPQDEKLKDAFSQVVENTAFFGDVVLRFPRIVHHYFDHNSNWNLLIRWGISFCNQSGVFDQGPHSPILGLMAQELGISEKHSDFQNPFKVDRTEFISSTDPFQKALREEEKRRKKEEKRKEIRKGPRISRSQSEL", "length": 227, "header": "tr|A0AAA9TMD3-1|E1BFW1_BOVIN Computationally mapped isoform of Coiled-coil domain containing 134 OS=Bos taurus OX=9913 GN=CCDC134 PE=4 SV=2 CANONICAL=E1BFW1-1" }, "locus": { "chromosome": "5", "start_pos": 112828485, "end_pos": 112813821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102807.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102807.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099639.2", "url": "https://www.ensembl.org/id/ENSBTAP00000099639.2" } ] } }, { "isoform_ac": "E1BFW1-1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1/entry#E1BFW1-1", "sequence": { "sequence": "MDLLQFLTSLSVLLLSGTGVTDTLRTSLDPSLEIYKKMFEVKRREQLLALKNLAQLNDVHQQYKILDVMLKGLFKVLEDSRTVLTAAGVLPDGPFPQDEKLKDAFSQVVENTAFFGDVVLRFPRIVHHYFDHNSNWNLLIRWGISFCNQSGVFDQGPHSPILGLMAQELGISEKHSDFQNPFKVDRTEFISSTDPFQKALREEEKRRKKEEKRKEIRKGPRISRSQSEL", "length": 229, "header": "tr|E1BFW1-1|E1BFW1_BOVIN Isoform 1 of Coiled-coil domain containing 134 OS=Bos taurus OX=9913 GN=CCDC134 PE=4 SV=1 CANONICAL=E1BFW1-1" }, "locus": { "chromosome": "5", "start_pos": 112828485, "end_pos": 112815386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028215.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028215.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028215.4", "url": "https://www.ensembl.org/id/ENSBTAP00000028215.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:516012", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516012", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KTT4-1", "protein_name": "Coiled-coil domain-containing protein 134", "gene_name": "ccdc134", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSVCALLLLAAPAALGSDSDRHRHDSNLEIYKRLFETKRKDQLNALKNLVELNDVNQQYKIIDIMLKGLFKVLEDSRAVLIAANMRPDDPFPLDDKLKEAYSHVVENTAFFGDVALRFPRIVHHYYERNADWSVLLRWGLSFCNHTGVFSGGAHQHVLTLMSQELGITEKSADFVNPYRTERDDVLQTAEAFQKILREEEKRRRKEEKRKEIRKGPRISRSRNEL", "length": 226 }, "evidence": [ { "id": "E1BFW1", "url": "https://omabrowser.org/oma/group/E1BFW1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A287A6Q1-1", "protein_name": "Coiled-coil domain containing 134", "gene_name": "CCDC134", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLLQFPAFLSVLLLSGTAVTGTLSTSLDPSLEIYKKMFEVKRREQLLALKNLAQLNDVHQQYKILDVMLKGLFKVLEDSRTVLIAANVLPEGPFPQDEKLKDAFSQVVENTAFFGDVVLRFPRIVHHYFDHNSNWNLLIRWGISFCNQSGVFDQGPHSPILSLMAQELGISEKDSDFQNPFKVDRTEFISSTDPFQKALREEEKRRKKEEKRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BFW1", "url": "https://omabrowser.org/oma/group/E1BFW1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MJE0-1", "protein_name": "Coiled-coil domain-containing protein 134", "gene_name": "Ccdc134", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLLQFLVSFFVLLLSGSEVTGTQKTTLDPSLKIYKKMFEVKRREQLLALKNLAQLNDIHQQYKILDVMLKGLFKVLEDSRTVLTAANVLPDGPLPQDEKLKDAFSHVVENTAFFGDVVLRFPKIVHHYFDHNSNWNLLIRWGISFCNQTGVFDQGPHSPILNLMAQELGISEKDSDFQNPFKIDRTEFIPSTDPFQKALREEEKRRKKEERRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BFW1", "url": "https://omabrowser.org/oma/group/E1BFW1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BVM7-1", "protein_name": "Coiled-coil domain containing 134", "gene_name": "CCDC134", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDFLWICLILLAVVLPEGSLADLEKQRMGSGLEIYKKLFEVKRKDQMNALKNLIELNDINQQYKIIDIMLKGLFKVLEDSRAVLIAADVPPDGPFPQDEKLKDAYSHVVENTAFFGDVVLRFPKIVHHYFDRNSNWNNLIRWGIGFCNLTGVFEQGPHSQLLGLMAQELGISEKSPNYRNPFKADHSEFFPSADTFQKALREEEKRRRKEEKRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BFW1", "url": "https://omabrowser.org/oma/group/E1BFW1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5M862-1", "protein_name": "Coiled-coil domain-containing protein 134", "gene_name": "Ccdc134", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLQSLAVFFVLLLPGTEVTGTLKSTLDPSLKIYKKMFEVKRREQLLALKNLAQLNDIHQQYKILDVMLKGLFKVLEDSRTVLIAADVLPDGPLPQDEKLKDAFSHVVENTAFFGDVVLRFPKIVHHYFDHNSNWNLLIRWGISFCNQTGVFDQGPHSPVLSLMAQELGITEKDSDFQNPFTIDRTEFIPSTDPFQKALREEEKRRKKEEKRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BFW1", "url": "https://omabrowser.org/oma/group/E1BFW1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C7V8-1", "protein_name": "Coiled-coil domain-containing protein 134", "gene_name": "Ccdc134", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLLQFLAAFSVLLWPGTEVTGALKSTLDPSLKIYKKMFEVKRREQLLALKNLAQLNDIHQQYKILDVMLKGLFKVLEDSRTVLIAADVLPDGPVPQDEKLKDAFSHVVENTAFFGDVVLRFPKIVHHYFDHNSNWNLLIRWGISFCNQTGVFDQGPHSPILSLMAQELGITEKDSDFRNPFKTDQTEFIPSTDPFQKALREEEKRRKKEERRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BFW1", "url": "https://omabrowser.org/oma/group/E1BFW1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H6E4-1", "protein_name": "Coiled-coil domain-containing protein 134", "gene_name": "CCDC134", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLLQFLAFLFVLLLSGMGATGTLRTSLDPSLEIYKKMFEVKRREQLLALKNLAQLNDIHQQYKILDVMLKGLFKVLEDSRTVLTAADVLPDGPFPQDEKLKDAFSHVVENTAFFGDVVLRFPRIVHYYFDHNSNWNLLIRWGISFCNQTGVFNQGPHSPILSLMAQELGISEKDSNFQNPFKIDRTEFIPSTDPFQKALREEEKRRKKEEKRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BFW1", "url": "https://omabrowser.org/oma/group/E1BFW1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "E1BFW1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BFW1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BFW1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of ossification", "id": "GO:0030278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030278", "evidence": [ { "database": "UniProtKB", "id": "E1BFW1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1" } ], "pmid": "" }, { "name": "regulation of glycoprotein biosynthetic process", "id": "GO:0010559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010559", "evidence": [ { "database": "UniProtKB", "id": "E1BFW1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway", "id": "GO:0030177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030177", "evidence": [ { "database": "UniProtKB", "id": "E1BFW1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1" } ], "pmid": "" }, { "name": "positive regulation of MyD88-dependent toll-like receptor signaling pathway", "id": "GO:0034126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034126", "evidence": [ { "database": "UniProtKB", "id": "E1BFW1", "url": "https://www.uniprot.org/uniprotkb/E1BFW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJZ5-1", "uniprot_ac": "E1BJZ5", "uniprot_id": "E1BJZ5_BOVIN", "mass": { "chemical_mass": 110788.0, "monoisotopic_mass": 110788.0 }, "refseq": { "ac": "NP_001179765", "name": "sal-like protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179765" }, "gene_names": [ { "name": "SALL4", "type": "recommended", "evidence": [ { "id": "E1BJZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ] }, { "name": "SALL4", "type": "synonym", "evidence": [ { "id": "NP_001179765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179765" } ] } ], "protein_names": [ { "name": "Sal-like protein 4", "type": "recommended", "evidence": [ { "id": "E1BJZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein SALL4", "type": "synonym", "evidence": [ { "id": "E1BJZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5/entry#names_and_taxonomy" } ] }, { "name": "sal-like 4", "type": "synonym", "evidence": [ { "id": "NP_001179765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179765" } ] }, { "name": "sal-like protein 4", "type": "synonym", "evidence": [ { "id": "NP_001179765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179765" } ] } ], "function": [ { "annotation": "Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.", "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5#function" }, { "database": "UniProtKB", "id": "ARBA00054938", "url": "https://www.uniprot.org/uniprotkb/ARBA00054938#function" }, { "database": "UniProtKB", "id": "A0AAA9S6K0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6K0#function" }, { "database": "UniProtKB", "id": "A0AAA9TL65", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL65#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SALL4", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5", "locus": { "chromosome": "13", "start_pos": 79567590, "end_pos": 79583684, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003101", "url": "https://www.ensembl.org/id/ENSBTAG00000003101" } ] } } ], "crossref": [ { "id": "E1BJZ5", "url": "https://alphafold.ebi.ac.uk/entry/E1BJZ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003101", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003101", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "541170", "url": "https://www.ncbi.nlm.nih.gov/gene/541170", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541170", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541170", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIRMNPY", "url": "https://omabrowser.org/oma/group/HIRMNPY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJZ5", "url": "https://www.orthodb.org/?gene=E1BJZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23233:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23233:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8943724", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8943724", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179765", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179765", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S6K0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6K0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWZ7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TL65", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TL65-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJZ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRKQAKPQHINSEEDQGERQPQQPAPECADAAPAAPAAGAPGAPMNYLGGRGNDELNGDGAGIKRPRREETHVCEKCCAEFFSFSEFLDHKKNCTKTPPVLILKDSEGPMSSEDLSGTVLSPQPPSPGRREGHRDNGSGGGAPGDLREKPGAESVLYLKTEAALPPAPQDISYLPKGKVANTNVTLQALRGTKVAVNQRSADVPPAPVPGAGSLPWVLEQILCLQQQQLQQIQLTEQIRVQVNMWASHALHAGHAADSLKTLGGHVSQQVSAAVALLSQKAGSAGLPLDALKPAKLPHANVPSAGGSASPGLPPFALKPDATRVLPGVLSRLPGALLPQAQGSVLFQSPFSAVALDPSKKGKGKPPSVSPVEVKLKDEALCRHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVHFHRHPQVKANPQLFADFHDKTAVGGGLPFALAGPVPLEEAGLSLDSKPALAAGTPSVVGLAQNLPSGPHPKDVAGGPLPGDLQPGPSPESEDGSILPGVGPTHPSPRVGGFPGGGPPEPGSETLKLQRLVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFPCKVCGRAFSTKGNLKTHLGVHRTSASVKTQHSCPICQKKFTNAVLLQQHIRMHMGGQIPNTPLPESPCEFAGPEPSAAGENGSPGAPAHDGVMEAIDVDEACPQEAAPSSSSRVLGPLAGVLAASPTPGLATAASLDAPVKAGLAALVLQRQGSRENGSVESDGLTNDDASSVMGDPECASRSPDVLESTSFQAVSPAHSQAESVKSKSPDADGKGDGSESSRTEMEGRSSVPSTFIRAQPTYVKVEVPGGFVGPTTMSPGMTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTHGANNSSARRGRKLAIENTMALLGTDAKRVPEMFPKEIVAPSVSVDPVVWSQYATMLNGGLAMKTNEISVIQSGGVPTLPVSLGASSVVNNTAASKIDGSQSAAGAEVEKPGTADNVPKHQFPHLLEENKIAVS", "length": 1061, "header": "tr|E1BJZ5-1|E1BJZ5_BOVIN Isoform 1 of Sal-like protein 4 OS=Bos taurus OX=9913 GN=SALL4 PE=3 SV=3 CANONICAL=E1BJZ5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S6K0-1", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5/entry#A0AAA9S6K0-1", "sequence": { "sequence": "MSRRKQAKPQHINSEEDQGERQPQQPAPECADAAPAAPAAGAPGCTHNRTAKKRKQSSHLQSLHSPGPRHLAEAWLPSAPMNYLGGRGNDELNGDGAGIKRPRREETHVCEKCCAEFFSFSEFLDHKKNCTKTPPVLILKDSEGPMSSEDLSGTVLSPQPPSPGRREGHRDNGSGGGAPGDLREKPGAESVLYLKTEAALPPAPQDISYLPKGKVANTNVTLQALRGTKVAVNQRSADVPPAPVPGAGSLPWVLEQILCLQQQQLQQIQLTEQIRVQVNMWASHALHAGHAADSLKTLGGHVSQQVSAAVALLSQKAGSAGLPLDALKPAKLPHANVPSAGGSASPGLPPFALKPDATRVLPGVLSRLPGALLPQAQGSVLFQSPFSAVALDPSKKGKGKPPSVSPVEVKLKDEALCRHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVHFHRHPQVKANPQLFADFHDKTAVGGGLPFALAGPVPLEEAGLSLDSKPALAAGTPSVVGLAQNLPSGPHPKDVAGGPLPGDLQPGPSPESEDGSILPGVGPTHPSPRVGGFPGGGPPEPGSETLKLQRLVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFPCKVCGRAFSTKGNLKTHLGVHRTSASVKTQHSCPICQKKFTNAVLLQQHIRMHMGGQIPNTPLPESPCEFAGPEPSAAGENGSPGAPAHDGVMEAIDVDEACPQEAAPSSSSRVLGPLAGVLAASPTPGLATAASLDAPVKAGLAALVLQRQGSRENGSVESDGLTNDDASSVMGDPECASRSPDVLESTSFQAVSPAHSQAESVKSKSPDADGKGDGSESSRTEMEGRSSVPSTFIRAQPTYVKVEVPGGFVGPTTMSPGMTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTHGANNSSARRGRKLAIENTMALLGTDAKRVPEMFPKEIVAPSVSVDPVVWSQYATMLNGGLAMKTNEISVIQSGGVPTLPVSLGASSVVNNTAASKIDGSQSAAGAEVEKPGTADNVPKHQFPHLLEENKIAVS", "length": 1095, "header": "tr|A0AAA9S6K0-1|E1BJZ5_BOVIN Computationally mapped isoform of Sal-like protein 4 OS=Bos taurus OX=9913 GN=SALL4 PE=3 SV=1 CANONICAL=E1BJZ5-1" }, "locus": { "chromosome": "13", "start_pos": 79583485, "end_pos": 79567787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104792.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104792.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080821.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080821.1" } ] } }, { "isoform_ac": "A0AAA9SWZ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5/entry#A0AAA9SWZ7-1", "sequence": { "sequence": "MSRRKQAKPQHINSEEDQGERQPQQPAPECADAAPAAPAAGAPGRSSVPSTFIRAQPTYVKVEVPGGFVGPTTMSPGMTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTHGANNSSARRGRKLAIENTMALLGTDAKRVPEMFPKEIVAPSVSVDPVVWSQYATMLNGGLAMKTNEISVIQSGGVPTLPVSLGASSVVNNTAASKIDGSQSAAGAEVEKPGTADNVPKHQFPHLLEENKIAVS", "length": 276, "header": "tr|A0AAA9SWZ7-1|E1BJZ5_BOVIN Computationally mapped isoform of Sal-like protein 4 OS=Bos taurus OX=9913 GN=SALL4 PE=3 SV=1 CANONICAL=E1BJZ5-1" }, "locus": { "chromosome": "13", "start_pos": 79583485, "end_pos": 79567787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129763.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129763.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089844.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089844.1" } ] } }, { "isoform_ac": "A0AAA9TL65-1", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5/entry#A0AAA9TL65-1", "sequence": { "sequence": "MSRRKQAKPQHINSEEDQGERQPQQPAPECADAAPAAPAAGAPGAPMNYLGGRGNDELNGDGAGIKRPRREETHVCEKCCAEFFSFSEFLDHKKNCTKTPPVLILKDSEGPMSSEDLSGTVLSPQPPSPGRREGHRDNGSGGGAPGDLREKPGAESVLYLKTEAALPPAPQDISYLPKGKVANTNVTLQALRGTKVAVNQRSADVPPAPVPGAGSLPWVLEQILCLQQQQLQQIQLTEQIRVQVNMWASHALHAGHAADSLKTLGGHVSQQVSAAVALLSQKAGSAGLPLDALKPAKLPHANVPSAGGSASPGLPPFALKPDATRVLPGVLSRLPGALLPQAQGSVLFQSPFSAVALDPSKKGKGKPPSVSPVEVKLKDEALCRHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVHFHRHPQVKANPQLFADFHDKTAVGGGLPFALAGPVPLEEAGLSLDSKPALAAGTPSVVGLAQNLPSGPHPKDVAGGPLPGDLQPGPSPESEDGSILPGVGPTHPSPRVGGFPGGGPPEPGSETLKLQRLVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFPCKVCGRAFSTKGNLKTHLGVHRTSASVKTQHSCPICQKKFTNAVLLQQHIRMHMGGQIPNTPLPESPCEFAGPEPSAAGENGSPGAPAHDGVMEAIDVDEACPQEAAPSSSSRVLGPLAGVLAASPTPGLATAASLDAPVKAGLAALVLQRQGSRENGSVESDGLTNDDASSVMGDPECASRSPDVLESTSFQAVSPAHSQAESVKSKSPDADGKGDGSESSRTEMEGRSSVPSTFIRAQPTYVKVEVPGGFVGPTTMSPGMTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKGQVTACLHCWVPGSSPGWGTKILPALQCSEKKKEKRNRLSHSISEVGMFVAFIKSCRSGNIDCDCHARNIKWINPV", "length": 998, "header": "tr|A0AAA9TL65-1|E1BJZ5_BOVIN Computationally mapped isoform of Sal-like protein 4 OS=Bos taurus OX=9913 GN=SALL4 PE=3 SV=1 CANONICAL=E1BJZ5-1" }, "locus": { "chromosome": "13", "start_pos": 79583485, "end_pos": 79569434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092148.1", "url": "https://www.ensembl.org/id/ENSBTAT00000092148.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097029.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097029.1" } ] } }, { "isoform_ac": "E1BJZ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5/entry#E1BJZ5-1", "sequence": { "sequence": "MSRRKQAKPQHINSEEDQGERQPQQPAPECADAAPAAPAAGAPGAPMNYLGGRGNDELNGDGAGIKRPRREETHVCEKCCAEFFSFSEFLDHKKNCTKTPPVLILKDSEGPMSSEDLSGTVLSPQPPSPGRREGHRDNGSGGGAPGDLREKPGAESVLYLKTEAALPPAPQDISYLPKGKVANTNVTLQALRGTKVAVNQRSADVPPAPVPGAGSLPWVLEQILCLQQQQLQQIQLTEQIRVQVNMWASHALHAGHAADSLKTLGGHVSQQVSAAVALLSQKAGSAGLPLDALKPAKLPHANVPSAGGSASPGLPPFALKPDATRVLPGVLSRLPGALLPQAQGSVLFQSPFSAVALDPSKKGKGKPPSVSPVEVKLKDEALCRHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVHFHRHPQVKANPQLFADFHDKTAVGGGLPFALAGPVPLEEAGLSLDSKPALAAGTPSVVGLAQNLPSGPHPKDVAGGPLPGDLQPGPSPESEDGSILPGVGPTHPSPRVGGFPGGGPPEPGSETLKLQRLVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFPCKVCGRAFSTKGNLKTHLGVHRTSASVKTQHSCPICQKKFTNAVLLQQHIRMHMGGQIPNTPLPESPCEFAGPEPSAAGENGSPGAPAHDGVMEAIDVDEACPQEAAPSSSSRVLGPLAGVLAASPTPGLATAASLDAPVKAGLAALVLQRQGSRENGSVESDGLTNDDASSVMGDPECASRSPDVLESTSFQAVSPAHSQAESVKSKSPDADGKGDGSESSRTEMEGRSSVPSTFIRAQPTYVKVEVPGGFVGPTTMSPGMTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTHGANNSSARRGRKLAIENTMALLGTDAKRVPEMFPKEIVAPSVSVDPVVWSQYATMLNGGLAMKTNEISVIQSGGVPTLPVSLGASSVVNNTAASKIDGSQSAAGAEVEKPGTADNVPKHQFPHLLEENKIAVS", "length": 1061, "header": "tr|E1BJZ5-1|E1BJZ5_BOVIN Isoform 1 of Sal-like protein 4 OS=Bos taurus OX=9913 GN=SALL4 PE=3 SV=3 CANONICAL=E1BJZ5-1" }, "locus": { "chromosome": "13", "start_pos": 79583485, "end_pos": 79567787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004035.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004035.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004035.6", "url": "https://www.ensembl.org/id/ENSBTAP00000004035.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 533, "start_aa": "Thr", "end_pos": 533, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr533", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 728, "start_aa": "Thr", "end_pos": 728, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr728", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:541170", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541170", "resource": "KEGG Pathway" }, { "id": "R-BTA-8943724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8943724", "resource": "Reactome", "description": "Regulation of PTEN gene transcription" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BJZ5", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1017, "end_pos": 1019, "annotation": "n_glycosylation_sequon" }, { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 682, "end_pos": 684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" }, { "start_pos": 931, "end_pos": 933, "annotation": "n_glycosylation_sequon" }, { "start_pos": 932, "end_pos": 934, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJZ5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 385, "end_pos": 412, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 533, 728 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1017, "end_pos": 1019 }, { "start_pos": 138, "end_pos": 140 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 682, "end_pos": 684 }, { "start_pos": 758, "end_pos": 760 }, { "start_pos": 886, "end_pos": 888 }, { "start_pos": 931, "end_pos": 933 }, { "start_pos": 932, "end_pos": 934 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDX4-1", "uniprot_ac": "E1BDX4", "uniprot_id": "E1BDX4_BOVIN", "mass": { "chemical_mass": 87263.0, "monoisotopic_mass": 87263.0 }, "refseq": {}, "gene_names": [ { "name": "ZBTB17", "type": "recommended", "evidence": [ { "id": "E1BDX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 17", "type": "recommended", "evidence": [ { "id": "E1BDX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDX4/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 151", "type": "synonym", "evidence": [ { "id": "E1BDX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDX4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZBTB17", "url": "https://www.uniprot.org/uniprotkb/E1BDX4", "locus": { "chromosome": "16", "start_pos": 51633362, "end_pos": 51602848, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018730", "url": "https://www.ensembl.org/id/ENSBTAG00000018730" } ] } } ], "crossref": [ { "id": "E1BDX4", "url": "https://alphafold.ebi.ac.uk/entry/E1BDX4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018730", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018730", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18206", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18206", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BDX4", "url": "https://www.orthodb.org/?gene=E1BDX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SB07", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SB07-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T0H5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T0H5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDX4-1", "url": "https://www.uniprot.org/uniprotkb/E1BDX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVDFKAHKAVLAACSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLSLSSENVDDVLAVASFLQMQDIITACHALKSLAEPAASPGENMEASAAEVGDKRAKEEKAAATPLSELDPARSSPPTGPGREPKEERGGQAESTGSGAEQTEKADAPREPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEREEEEGAAPAVVKEEGPPLEKGEAPEESEESASTDSGQELGAEARGLRSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCVHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGGEVSVVTVDDMVTLATEALAATAVTQLTGLAIPPTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGSTWPAGQVLQAGELVFRPRDGADGQPALAETPPTAPECPPPAE", "length": 800, "header": "tr|E1BDX4-1|E1BDX4_BOVIN Isoform 1 of Zinc finger and BTB domain-containing protein 17 OS=Bos taurus OX=9913 GN=ZBTB17 PE=3 SV=4 CANONICAL=E1BDX4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SB07-1", "url": "https://www.uniprot.org/uniprotkb/E1BDX4/entry#A0AAA9SB07-1", "sequence": { "sequence": "MGLQASKAESSRLPKGQARDWHSVTAGQSHTEPPRFSWSLVAAMDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVDFKAHKAVLAACSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLSLSSENVDDVLAVASFLQMQDIITACHALKSLAEPAASPGENMEASAAEVGDKRAKEEKAAATPLSELDPARSSPPTGPGREPKEERGGQAESTGSGAEQTEKADAPREPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEREEEEGAAPAVVKEEGPPLEKGEAPEESEESASTDSGQELGAEARGLRSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCVHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGGEVSVVTVDDMVTLATEALAATAVTQLTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGSTWPAGQVLGAGPKGLGHTAYQDPGHPCRAQLEGSFSQSSKVGRVPNQAGHRPGSFGLKEARAHHTCFMVTLAARSRPGQRHLLGTFTCPQSVDLLR", "length": 890, "header": "tr|A0AAA9SB07-1|E1BDX4_BOVIN Computationally mapped isoform of Zinc finger and BTB domain-containing protein 17 OS=Bos taurus OX=9913 GN=ZBTB17 PE=3 SV=1 CANONICAL=E1BDX4-1" }, "locus": { "chromosome": "16", "start_pos": 51632358, "end_pos": 51621042, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104679.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104679.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079360.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079360.1" } ] } }, { "isoform_ac": "A0AAA9SJM1-1", "url": "https://www.uniprot.org/uniprotkb/E1BDX4/entry#A0AAA9SJM1-1", "sequence": { "sequence": "MDIYLEICSFLKGEPACFFSLENTDLEKDPAMDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVDFKAHKAVLAACSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLSLSSENVDDVLAVASFLQMQDIITACHALKSLAEPAASPGENMEASAAEVGDKRAKEEKAAATPLSELDPARSSPPTGPGREPKEERGGQAESTGSGAEQTEKADAPREPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEREEEEGAAPAVVKEEGPPLEKGEAPEESEESASTDSGQELGAEARGLRSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCVHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGGEVSVVTVDDMVTLATEALAATAVTQLTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGSTWPAGQVLQAGELVFRPRDGADGQPALAETPPTAPECPPPAE", "length": 824, "header": "tr|A0AAA9SJM1-1|E1BDX4_BOVIN Computationally mapped isoform of Zinc finger and BTB domain-containing protein 17 OS=Bos taurus OX=9913 GN=ZBTB17 PE=3 SV=1 CANONICAL=E1BDX4-1" }, "locus": { "chromosome": "16", "start_pos": 51631655, "end_pos": 51624610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134257.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134257.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084091.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084091.1" } ] } }, { "isoform_ac": "A0AAA9T0H5-1", "url": "https://www.uniprot.org/uniprotkb/E1BDX4/entry#A0AAA9T0H5-1", "sequence": { "sequence": "MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVDFKAHKAVLAACSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLSLSSENVDDVLAVASFLQMQDIITACHALKSLAEPAASPGENMEASAAEGAEQTEKADAPREPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEREEEEGAAPAVVKEEGPPLEKGEAPEESEESASTDSGQELGAEARGLRSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCVHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGGEVSVVTVDDMVTLATEALAATAVTQLTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGSTWPAGQVLQAGELVFRPRDGADGQPALAETPPTAPECPPPAE", "length": 746, "header": "tr|A0AAA9T0H5-1|E1BDX4_BOVIN Computationally mapped isoform of Zinc finger and BTB domain-containing protein 17 OS=Bos taurus OX=9913 GN=ZBTB17 PE=3 SV=1 CANONICAL=E1BDX4-1" }, "locus": { "chromosome": "16", "start_pos": 51631655, "end_pos": 51625615, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098563.2", "url": "https://www.ensembl.org/id/ENSBTAT00000098563.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090018.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090018.1" } ] } }, { "isoform_ac": "E1BDX4-1", "url": "https://www.uniprot.org/uniprotkb/E1BDX4/entry#E1BDX4-1", "sequence": { "sequence": "MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVDFKAHKAVLAACSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLSLSSENVDDVLAVASFLQMQDIITACHALKSLAEPAASPGENMEASAAEVGDKRAKEEKAAATPLSELDPARSSPPTGPGREPKEERGGQAESTGSGAEQTEKADAPREPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEREEEEGAAPAVVKEEGPPLEKGEAPEESEESASTDSGQELGAEARGLRSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCVHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGGEVSVVTVDDMVTLATEALAATAVTQLTGLAIPPTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGSTWPAGQVLQAGELVFRPRDGADGQPALAETPPTAPECPPPAE", "length": 800, "header": "tr|E1BDX4-1|E1BDX4_BOVIN Isoform 1 of Zinc finger and BTB domain-containing protein 17 OS=Bos taurus OX=9913 GN=ZBTB17 PE=3 SV=4 CANONICAL=E1BDX4-1" }, "locus": { "chromosome": "16", "start_pos": 51631655, "end_pos": 51625615, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044658.6", "url": "https://www.ensembl.org/id/ENSBTAT00000044658.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042135.5", "url": "https://www.ensembl.org/id/ENSBTAP00000042135.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "protein-DNA complex", "id": "GO:0032993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032993", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "transcription coactivator binding", "id": "GO:0001223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001223", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BDX4", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 86, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BDX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDX4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 323, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BER3-1", "uniprot_ac": "E1BER3", "uniprot_id": "E1BER3_BOVIN", "mass": { "chemical_mass": 85629.0, "monoisotopic_mass": 85629.0 }, "refseq": { "ac": "NP_001192986", "name": "inactive carboxypeptidase-like protein X2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192986" }, "gene_names": [ { "name": "CPXM2", "type": "recommended", "evidence": [ { "id": "E1BER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER3" } ] }, { "name": "CPXM2", "type": "synonym", "evidence": [ { "id": "NP_001192986", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192986" } ] } ], "protein_names": [ { "name": "Inactive carboxypeptidase-like protein X2", "type": "recommended", "evidence": [ { "id": "E1BER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER3/entry#names_and_taxonomy" } ] }, { "name": "inactive carboxypeptidase-like protein X2 precursor", "type": "synonym", "evidence": [ { "id": "NP_001192986", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192986" } ] } ], "function": [ { "annotation": "May be involved in cell-cell interactions.", "evidence": [ { "database": "UniProtKB", "id": "E1BER3", "url": "https://www.uniprot.org/uniprotkb/E1BER3#function" }, { "database": "UniProtKB", "id": "ARBA00053417", "url": "https://www.uniprot.org/uniprotkb/ARBA00053417#function" }, { "database": "UniProtKB", "id": "A0AAA9T9R4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9R4#function" }, { "database": "UniProtKB", "id": "A0AAA9TCM8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCM8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BER3", "url": "https://www.uniprot.org/uniprotkb/E1BER3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CPXM2", "url": "https://www.uniprot.org/uniprotkb/E1BER3", "locus": { "chromosome": "26", "start_pos": 43495815, "end_pos": 43632953, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018941", "url": "https://www.ensembl.org/id/ENSBTAG00000018941" } ] } } ], "crossref": [ { "id": "E1BER3", "url": "https://alphafold.ebi.ac.uk/entry/E1BER3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018941", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018941", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00057", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00057", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03869", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03869", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11308", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11308", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534505", "url": "https://www.ncbi.nlm.nih.gov/gene/534505", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534505", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534505", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QHGKGIP", "url": "https://omabrowser.org/oma/group/QHGKGIP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BER3", "url": "https://www.orthodb.org/?gene=E1BER3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11532", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11532", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11532:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11532:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192986", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192986", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SBX3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBX3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCB4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCB4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9R4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9R4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCM8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCM8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BER3", "url": "https://www.uniprot.org/uniprotkb/E1BER3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BER3-1", "url": "https://www.uniprot.org/uniprotkb/E1BER3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARRGAAALVLALALLAVAPARVGARGAAVEDPNDDIQETWSLEPSYARREPEPEPFSPPLPAGPGAGERGPRPPQPRPPKKATTKPKKAPKREKLAPQTPRPGKNINRKGMRTKSSEKAASDDHGVPLARDAVREGCPPLGLETLKITDFQLHASTSKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLHQWIEVDARRLTKFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDDLDFKHHNHKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELMLLLMQFLCQEYLAGNLRIVRLVEETRIHILPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNIPRKVPNHYIAIPEWFLSENATVAVETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDMVRSLWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEDGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESELPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAVISVEGVNHDIRTASDGDYWRLLNPGEYVVTAKAEGFTSSTKNCMVGYDMGATQCDFTLSKTNLARIREIMEKFRKQPVSLPARRLKLQGRKRRQRG", "length": 758, "header": "tr|E1BER3-1|E1BER3_BOVIN Isoform 1 of Inactive carboxypeptidase-like protein X2 OS=Bos taurus OX=9913 GN=CPXM2 PE=3 SV=3 CANONICAL=E1BER3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SBX3-1", "url": "https://www.uniprot.org/uniprotkb/E1BER3/entry#A0AAA9SBX3-1", "sequence": { "sequence": "MARRGAAALVLALALLAVAPARVGARGAAVEDPNDDIQETWSLEPSYARREPEPEPFSPPLPAGPGAGERGPRPPQPRPPKKATTKPKKAPKREKLAPQTPRPGKNINRKGMRTKSSEKAASDDHGVPLARDAVREGCPPLGLETLKITDFQLHASTSKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLHQWIEVDARRLTKFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDDLDFKHHNHKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELMLLLMQFLCQEYLAGNLRIVRLVEETRIHILPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNIPRKVPNHYIAIPEWFLSENATVAVETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDMVRSLWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEDGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESELPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAVISVEGVNHDIRTEVKSPTLIRLFYIYSHAKGSQETRHRWLFKMAFCGKGIRFRSSSS", "length": 719, "header": "tr|A0AAA9SBX3-1|E1BER3_BOVIN Computationally mapped isoform of Inactive carboxypeptidase-like protein X2 OS=Bos taurus OX=9913 GN=CPXM2 PE=3 SV=1 CANONICAL=E1BER3-1" }, "locus": { "chromosome": "26", "start_pos": 43632754, "end_pos": 43497471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122786.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122786.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083594.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083594.1" } ] } }, { "isoform_ac": "A0AAA9SCB4-1", "url": "https://www.uniprot.org/uniprotkb/E1BER3/entry#A0AAA9SCB4-1", "sequence": { "sequence": "MARRGAAALVLALALLAVAPARVGARGAAVEDPNDDIQETWSLEPSYARREPEPEPFSPPLPAGPGAGERGPRPPQPRPPKKATTKPKKAPKREKLAPQTPRPGKNINRKGMRTKSSEKAASDDHGVPLARDAVREGCPPLGLETLKITDFQLHASTSKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLHQWIEVDARRLTKFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDDLDFKHHNHKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELMLLLMQFLCQEYLAGNLRIVRLVEETRIHILPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNIPRKVPNHYIAIPEWFLSENATVAVETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDMVRSLWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEDGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESELPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAVISVEGVNHDIRTGGSQMLREAGGPTEGSGASDGDYWRLLNPGEYVVTAKAEGFTSSTKNCMVGYDMGATQCDFTLSKTNLARIREIMEKFRKQPVSLPARRLKLQGRKRRQRG", "length": 775, "header": "tr|A0AAA9SCB4-1|E1BER3_BOVIN Computationally mapped isoform of Inactive carboxypeptidase-like protein X2 OS=Bos taurus OX=9913 GN=CPXM2 PE=3 SV=1 CANONICAL=E1BER3-1" }, "locus": { "chromosome": "26", "start_pos": 43632754, "end_pos": 43496908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125633.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125633.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083026.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083026.1" } ] } }, { "isoform_ac": "A0AAA9T9R4-1", "url": "https://www.uniprot.org/uniprotkb/E1BER3/entry#A0AAA9T9R4-1", "sequence": { "sequence": "MRRGRLSFIHWSPPVRHCPRCLDIWRPCAPHDFQRGKNINRKGMRTKSSEKAASDDHGVPLARDAVREGCPPLGLETLKITDFQLHASTSKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLHQWIEVDARRLTKFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDDLDFKHHNHKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELMLLLMQFLCQEYLAGNLRIVRLVEETRIHILPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNIPRKVPNHYIAIPEWFLSENATVAVETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDMVRSLWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEDGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESELPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAVISVEGVNHDIRTASDGDYWRLLNPGEYVVTAKAEGFTSSTKNCMVGYDMGATQCDFTLSKTNLARIREIMEKFRKQPVSLPARRLKLQGRKRRQRG", "length": 690, "header": "tr|A0AAA9T9R4-1|E1BER3_BOVIN Computationally mapped isoform of Inactive carboxypeptidase-like protein X2 OS=Bos taurus OX=9913 GN=CPXM2 PE=3 SV=1 CANONICAL=E1BER3-1" }, "locus": { "chromosome": "26", "start_pos": 43624011, "end_pos": 43496908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116734.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116734.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094740.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094740.1" } ] } }, { "isoform_ac": "A0AAA9TCM8-1", "url": "https://www.uniprot.org/uniprotkb/E1BER3/entry#A0AAA9TCM8-1", "sequence": { "sequence": "MARRGAAALVLALALLAVAPARVGARGAAVEDPNDDIQETWSLEPSYARREPEPEPFSPPLPAGPGAGERGPRPPQPRPPKKATTKPKKAPKREKLAPQTPRPGCPPLGLETLKITDFQLHASTSKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLHQWIEVDARRLTKFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDDLDFKHHNHKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELMLLLMQFLCQEYLAGNLRIVRLVEETRIHILPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNIPRKVPNHYIAIPEWFLSENATVAVETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDMVRSLWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEDGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESELPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAVISVEGVNHDIRTASDGDYWRLLNPGEYVVTAKAEGFTSSTKNCMVGYDMGATQCDFTLSKTNLARIREIMEKFRKQPVSLPARRLKLQGRKRRQRG", "length": 725, "header": "tr|A0AAA9TCM8-1|E1BER3_BOVIN Computationally mapped isoform of Inactive carboxypeptidase-like protein X2 OS=Bos taurus OX=9913 GN=CPXM2 PE=3 SV=1 CANONICAL=E1BER3-1" }, "locus": { "chromosome": "26", "start_pos": 43632754, "end_pos": 43496908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102697.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102697.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094613.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094613.1" } ] } }, { "isoform_ac": "E1BER3-1", "url": "https://www.uniprot.org/uniprotkb/E1BER3/entry#E1BER3-1", "sequence": { "sequence": "MARRGAAALVLALALLAVAPARVGARGAAVEDPNDDIQETWSLEPSYARREPEPEPFSPPLPAGPGAGERGPRPPQPRPPKKATTKPKKAPKREKLAPQTPRPGKNINRKGMRTKSSEKAASDDHGVPLARDAVREGCPPLGLETLKITDFQLHASTSKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLHQWIEVDARRLTKFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDDLDFKHHNHKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELMLLLMQFLCQEYLAGNLRIVRLVEETRIHILPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNIPRKVPNHYIAIPEWFLSENATVAVETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDMVRSLWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEDGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESELPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAVISVEGVNHDIRTASDGDYWRLLNPGEYVVTAKAEGFTSSTKNCMVGYDMGATQCDFTLSKTNLARIREIMEKFRKQPVSLPARRLKLQGRKRRQRG", "length": 758, "header": "tr|E1BER3-1|E1BER3_BOVIN Isoform 1 of Inactive carboxypeptidase-like protein X2 OS=Bos taurus OX=9913 GN=CPXM2 PE=3 SV=3 CANONICAL=E1BER3-1" }, "locus": { "chromosome": "26", "start_pos": 43632754, "end_pos": 43496908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025207.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025207.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025207.6", "url": "https://www.ensembl.org/id/ENSBTAP00000025207.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534505", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534505", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XDI9-1", "protein_name": "Inactive carboxypeptidase-like protein X2", "gene_name": "CPXM2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTALRKRSSCPSQLCPALCALGLVVLGGLSWAVPMDEQDYYLQEISNRDHYYSFPYPGEEYFSFTEQPKEEGTIRASEPEEHPGFKPSRKELKPKKSSKKGKAILEPPPDCPPLGLETLKITDFQLHASTAKRYGLGAHRGRLNIQAGVNENDFYDGAWCAGRNDPFQWIEVDARRLTKFTGVITQGRNSLWSSNWVTSFRVLVSNDSHAWTAVRNESGDVIFEGNSEKEIPVLNMLPVPLVARYIRINPRSWYEEGSICMRLEILGCPLPDPNNYYHRRNEMTTTDNLDFKHHNYKEMRQLMKTVNKMCPNITRIYNIGKSHQGLKLYAVEISDNPGEHEVGEPEFRYIAGAHGNEVLGRELILLLMQFMCQEYLAGNPRIVHLIEDTRIHLLPSVNPDGYDKAYKAGSELGGWSLGRWTQDGIDINNNFPDLNSLLWESEDQKKSKRKVPNHHIPIPDWYLSENATVAVETRAIIAWMEKIPFVLGGNLQGGELVVAYPYDMVRSLWKTQDYTPTPDDHVFRWLAYSYASTHRLMTDARRRACHTEDFQKEDGTVNGASWHTVAGSINDFSYLHTNCFELSIYVGCDKYPHESELPEEWENNRESLIVFMEQVHRGIKGIVKDTHGRGIPNAIISVEGVNHDIRTGADGDYWRLLNPGEYLVSVKAEGYTTATKNCEVGYDMGATLCDFTISKTNLARIKEIMRKFGKQPISLSLRRLRQRARQWRQRR", "length": 731 }, "evidence": [ { "id": "E1BER3", "url": "https://omabrowser.org/oma/group/E1BER3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0M7U0-1", "protein_name": "Inactive carboxypeptidase-like protein X2", "gene_name": "Cpxm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLGTAFPAVALALVAVALAGVRAQGEAFEEPDYYSQELWRRGRYYENGEPEPEPELFSPSQHEDLRVEEQEQQEPHQQGPRKPKKATKPKKAPKREKLVAETPPPGKNSNRKGRRSKNLEKAARDDHGVPVVREDVRESCPPLGLETLKITDFQLHASTTKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLHQWIEVDARRLTKFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNNEKETPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLLEFLCQEYLAQNTRIVRLVEETRIHILPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNAPRKVPNHYIAIPEWFLSENATVAMETRAIIAWMEKIPFVLGGNLQGGELVVAYPYDMVRSLWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEEFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESELPEEWENNRESLIVFMEQVHRGIKGIVRDLQGKGISNAIISVEGVNHDIRTASDGDYWRLLNPGEYVVTAKAEGFITSTKNCMVGYDMGATRCDFTLSKTNLARIREIMETFGKQPVNLPARRLKLRGRKRRQRGIGELQVGPPSGGELR", "length": 777 }, "evidence": [ { "id": "E1BER3", "url": "https://omabrowser.org/oma/group/E1BER3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N436-1", "protein_name": "Inactive carboxypeptidase-like protein X2", "gene_name": "CPXM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRPGTATPALALVLLAVTLAGVGAQGAALEDPDYYGQEIWSREPYYARPEPELETFSPPLPAGPGEEWERRPQEPRPPKRATKPKKAPKREKSAPEPPPPGKHSNKKVMRTKSSEKAANDDHSVRVAREDVRESCPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSKTNMARIREIMEKFGKQPVSLPARRLKLRGQKRRQRG", "length": 756 }, "evidence": [ { "id": "E1BER3", "url": "https://omabrowser.org/oma/group/E1BER3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D2L5-1", "protein_name": "Inactive carboxypeptidase-like protein X2", "gene_name": "Cpxm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLGTACPALALALALVAVALAGVRAQGAAFEEPDYYSQELWRRGRYYGHPEPEPEQELFSPSMHEDLRVEEQEQQEPHQQGHRTPKKAIKPKKAPKREKLVAETPPPGKNSNRKGRRSKNLEKAASDDHGVPVAHEDVRESCPPLGLETLKITDFQLHASTSKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLHQWIEVDARRLTKFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLLHFLCQEYSAQNARIVRLVEETRIHILPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNSLLWEAEDQQNAPRKVPNHYIAIPEWFLSENATVATETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDMVRSLWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESELPEEWENNRESLIVFMEQVHRGIKGIVRDLQGKGISNAVISVEGVNHDIRTASDGDYWRLLNPGEYVVTAKAEGFITSTKNCMVGYDMGATRCDFTLTKTNLARIREIMETFGKQPVSLPSRRLKLRGRKRRQRG", "length": 764 }, "evidence": [ { "id": "E1BER3", "url": "https://omabrowser.org/oma/group/E1BER3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BER3", "url": "https://www.uniprot.org/uniprotkb/E1BER3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BER3", "url": "https://www.uniprot.org/uniprotkb/E1BER3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BER3", "url": "https://www.uniprot.org/uniprotkb/E1BER3" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "E1BER3", "url": "https://www.uniprot.org/uniprotkb/E1BER3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER3" }, { "id": "PS50022", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F5/8 type C", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 295, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER3" }, { "id": "PS52035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M14", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 642, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 493, "end_pos": 495 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK10-1", "uniprot_ac": "E1BK10", "uniprot_id": "E1BK10_BOVIN", "mass": { "chemical_mass": 53555.0, "monoisotopic_mass": 53555.0 }, "refseq": {}, "gene_names": [ { "name": "ITGBL1", "type": "recommended", "evidence": [ { "id": "E1BK10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ] } ], "protein_names": [ { "name": "Integrin beta-like protein 1", "type": "recommended", "evidence": [ { "id": "E1BK10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK10/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ITGBL1", "url": "https://www.uniprot.org/uniprotkb/E1BK10", "locus": { "chromosome": "12", "start_pos": 78126514, "end_pos": 77891049, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000044027", "url": "https://www.ensembl.org/id/ENSBTAG00000044027" } ] } } ], "crossref": [ { "id": "E1BK10", "url": "https://alphafold.ebi.ac.uk/entry/E1BK10", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000044027", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044027", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CGNDCKK", "url": "https://omabrowser.org/oma/group/CGNDCKK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10082:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10082:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07974", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07974", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SGE3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGE3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5R3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5R3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5R3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TA83", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TA83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TA83-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TA83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK10-1", "url": "https://www.uniprot.org/uniprotkb/E1BK10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPAGLASVLLLVSSLLLPGGLSAVPQSFSPSLRSGPGAAACRLSRAESERRCRAPGQPPGGALCHGRGRCDCGVCICHVSEPGVYFGPLCECHEWVCETYDGSTCAGHGKCDCGRCKCDEGWFGDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGNGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCQAGWHGDKCEFQCDITPWESKRRCTSPDGKVCSNRGICVCGECSCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKVGWYGKKCEHPRSCPLSTEESIRKCQGSATLPCSGRGKCECGKCTCYPPGDSKVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCEKGWFGTLCQHPRKCNLTEEQSNSLCESADGILCSGKGSCHCGKCLCSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEIWLGTEYP", "length": 496, "header": "tr|E1BK10-1|E1BK10_BOVIN Isoform 1 of Integrin beta-like protein 1 OS=Bos taurus OX=9913 GN=ITGBL1 PE=4 SV=3 CANONICAL=E1BK10-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SGE3-1", "url": "https://www.uniprot.org/uniprotkb/E1BK10/entry#A0AAA9SGE3-1", "sequence": { "sequence": "MRPAGLASVLLLVSSLLLPGGLSAVPQSFSPSLRSGPGAAACRLSRAESERRCRAPGQPPGGALCHGRGRCDCGVCICHVSEPGVYFGPLCECHEWVCETYDGSTCAGTCHCGRCKCDNSDGNGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCQAGWHGDKCEFQCDITPWESKRRCTSPDGKVCSNRGICVCGECSCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKVGWYGKKCEHPRSCPLSTEESIRKCQGSATLPCSGRGKCECGKCTCYPPGDSKVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCEKGWFGTLCQHPRKCNLTEEQSNSLCESADGILCSGKGSCHCGKCLCSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEIWLGTEYP", "length": 447, "header": "tr|A0AAA9SGE3-1|E1BK10_BOVIN Computationally mapped isoform of Integrin beta-like protein 1 OS=Bos taurus OX=9913 GN=ITGBL1 PE=4 SV=1 CANONICAL=E1BK10-1" }, "locus": { "chromosome": "12", "start_pos": 78126183, "end_pos": 77891285, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099207.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099207.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082945.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082945.1" } ] } }, { "isoform_ac": "A0AAA9T5R3-1", "url": "https://www.uniprot.org/uniprotkb/E1BK10/entry#A0AAA9T5R3-1", "sequence": { "sequence": "SLLAAMETFNKGHGKCDCGRCKCDEGWFGDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGNGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCQAGWHGDKCEFQCDITPWESKRRCTSPDGKVCSNRGICVCGECSCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKVGWYGKKCEHPRSCPLSTEESIRKCQGSATLPCSGRGKCECGKCTCYPPGDSKVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCEKGWFGTLCQHPRKCNLTEEQSNSLCESADGILCSGKGSCHCGKCLCSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEIWLGTEYP", "length": 400, "header": "tr|A0AAA9T5R3-1|E1BK10_BOVIN Computationally mapped isoform of Integrin beta-like protein 1 OS=Bos taurus OX=9913 GN=ITGBL1 PE=4 SV=1 CANONICAL=E1BK10-1" }, "locus": { "chromosome": "12", "start_pos": 78126183, "end_pos": 77917581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130459.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130459.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091092.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091092.1" } ] } }, { "isoform_ac": "A0AAA9TA83-1", "url": "https://www.uniprot.org/uniprotkb/E1BK10/entry#A0AAA9TA83-1", "sequence": { "sequence": "MRPAGLASVLLLVSSLLLPGGLSAVPQSFSPSLRSGPGAAACRLSRAESERRCRAPGQPPGGALCHGRGRCDCGVCICHVSEPGVYFGPLCECHEWVCETYDGSTCAGHGKCDCGRCKCDEGWFGDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGNGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCQAGWHGDKCEFQCDITPWESKRRCTSPDGKVCSNRGICVCGECSCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKVGWYGKKCEHPRSCPLSTEESIRKCQGSATLPCSGRGEKIRFTELTTLILIHGMKLLEQVIFEDTDDCFIRSTNTHISLSLGVRTDWFDLLAVQGTLKILLQHHQTHLGKCECGKCTCYPPGDSKVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCEKGWFGTLCQHPRKCNLTEEQSNSLCESADGILCSGKGSCHCGKCLCSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEIWLGTEYP", "length": 568, "header": "tr|A0AAA9TA83-1|E1BK10_BOVIN Computationally mapped isoform of Integrin beta-like protein 1 OS=Bos taurus OX=9913 GN=ITGBL1 PE=4 SV=1 CANONICAL=E1BK10-1" }, "locus": { "chromosome": "12", "start_pos": 78126183, "end_pos": 77891285, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112306.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112306.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095621.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095621.1" } ] } }, { "isoform_ac": "E1BK10-1", "url": "https://www.uniprot.org/uniprotkb/E1BK10/entry#E1BK10-1", "sequence": { "sequence": "MRPAGLASVLLLVSSLLLPGGLSAVPQSFSPSLRSGPGAAACRLSRAESERRCRAPGQPPGGALCHGRGRCDCGVCICHVSEPGVYFGPLCECHEWVCETYDGSTCAGHGKCDCGRCKCDEGWFGDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGNGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCQAGWHGDKCEFQCDITPWESKRRCTSPDGKVCSNRGICVCGECSCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKVGWYGKKCEHPRSCPLSTEESIRKCQGSATLPCSGRGKCECGKCTCYPPGDSKVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCEKGWFGTLCQHPRKCNLTEEQSNSLCESADGILCSGKGSCHCGKCLCSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEIWLGTEYP", "length": 496, "header": "tr|E1BK10-1|E1BK10_BOVIN Isoform 1 of Integrin beta-like protein 1 OS=Bos taurus OX=9913 GN=ITGBL1 PE=4 SV=3 CANONICAL=E1BK10-1" }, "locus": { "chromosome": "12", "start_pos": 78126183, "end_pos": 77891285, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061277.3", "url": "https://www.ensembl.org/id/ENSBTAT00000061277.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053831.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053831.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XPU9-1", "protein_name": "Integrin beta-like protein 1", "gene_name": "ITGBL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHARGLLGLVLLMVSVGSVPSLRPATPPALRSSLGSPVLCLLPRAEAELRCRVPGGPLCSGRGRCDCGVCICQVTEAGKYYGPLCECQDWVCEIYDGKVCAGHGKCDCGKCKCDEGWYGEACQYPTTCNLTRKKSNEMCKNSQDIICSGAGTCQCGRCKCVNSGGSGLVYGKFCECDDRECIDDETEEICTGHGQCYCGNCYCEAGWHGDKCEFQCDITPWEIKKRCTSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERNCKAVYDRYSDDFCSGHGQCNCGKCDCKEGWTGKKCEHPRSCPLSAEESVKKCKGNSNLPCSGRGKCECGQCTCFPPGDNRVYGKNCECDDRQCESADGNVCGGHGICSCGRCVCQEGWFGKLCQYSRKCNMTEEESRSLCESADGVLCSGKGSCHCGKCICSPQEWYISGDFCECDDRDCDKHDGLICTGNGVCNCGNCECWEGWNGNACEIWLGTEYP", "length": 490 }, "evidence": [ { "id": "E1BK10", "url": "https://omabrowser.org/oma/group/E1BK10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RP09-1", "protein_name": "Integrin beta-like protein 1", "gene_name": "ITGBL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPAGFRNFLLLASSLLFAGLSAVPQSFSPSLRSGPGAACRLSRAESERRCRAPGQPPGGALCHGRGRCDCGVCICHVSEPGVYFGPLCECHEWVCETYDGSTCAGHGRCDCGKCLCDEGWSGDACQYPTKCDLTKKKSNQMCKNSQDVICSNAGTCHCGRCKCDNSDGNGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCQAGWHGDKCEFQCDITPWESKRRCTSPDGQVCSNRGICVCGECSCHDVDPTGDWGDVHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKVGWYGKKCEHPRSCPLTAEESLKKCQGSSALPCSGRGKCECGRCTCYPPGDSRVYGKTCECDNRRCEDLDGVVCGGHGSCSCGRCLCERGWFGKLCQHPRKCNMTEEQSKGLCESADGTLCSGKGSCHCGKCICSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICNCGNCECWDGWNGNACEIWLGTEYP", "length": 494 }, "evidence": [ { "id": "E1BK10", "url": "https://omabrowser.org/oma/group/E1BK10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95965-1", "protein_name": "Integrin beta-like protein 1", "gene_name": "ITGBL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPPGFRNFLLLASSLLFAGLSAVPQSFSPSLRSWPGAACRLSRAESERRCRAPGQPPGAALCHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQHPRKCNMTEEQSKNLCESADGILCSGKGSCHCGKCICSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEIWLGSEYP", "length": 494 }, "evidence": [ { "id": "E1BK10", "url": "https://omabrowser.org/oma/group/E1BK10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5PQQ8-1", "protein_name": "Integrin beta-like protein 1", "gene_name": "Itgbl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHPPGFKNFLLLVSSLFFIGLSAAPQSFSPSLRSLSGAPCRLSRAESERRCRAPGQPPGSALCHDRGRCECGVCICHVTEPGTYFGPLCECHDWVCETYDGKTCAGHGTCDCGKCKCDVGWSGEACQYPTKCDLTKKISNQMCKNSQDVICSNAGTCHCGRCKCDNSDGHGLIYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCEAGWHGDKCEFQCDITPWESKRRCTSPDGKVCSNRGTCVCGECSCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCRAGWYGKKCEHPKNCPLSAEESTRKCQGSSDLPCSGRGRCECGRCTCYPPGDSRVYGKTCECDDRRCEDLDGVVCGGRGTCSCGRCVCEKGWFGKLCQHPRKCNMTEEQSRSLCESADGTLCSGKGSCHCGKCICSGEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEIWLGTEYP", "length": 494 }, "evidence": [ { "id": "E1BK10", "url": "https://omabrowser.org/oma/group/E1BK10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VDV0-1", "protein_name": "Integrin beta-like protein 1", "gene_name": "Itgbl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPPGFRNFLLLVSSLLFIGLSAAPQSFLPSLRSLSGAPCRLSRAESERRCRAPGQPPGSALCHDRGRCECGVCICHVTEPGTYFGPLCECHEWICETYDGKTCAGHGNCDCGKCKCDVGWSGEACQYPTKCDLTKKISNQMCKNSQDVICSNAGTCHCGRCKCDNSDGHGLIYGKFCECDDRECIDDETEEVCGGHGKCYCGNCYCEAGWHGDKCEFQCDITPWESKRRCTSPDGKVCSNRGTCVCGECSCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCRAGWYGKKCEHPRNCPLSAEESTKKCQGSSDLPCSGRGRCECGRCTCYPPGDSRVYGKTCECDDRRCEDLDGVVCGGHGMCSCGRCVCEKGWFGKLCQHLRKCNMTEEQSRSLCESADGTLCSGKGSCHCGKCICSGEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEIWLGTEYP", "length": 494 }, "evidence": [ { "id": "E1BK10", "url": "https://omabrowser.org/oma/group/E1BK10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "pmid": "" }, { "name": "integrin complex", "id": "GO:0008305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008305", "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "pmid": "" }, { "name": "cell adhesion mediated by integrin", "id": "GO:0033627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033627", "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "E1BK10", "url": "https://www.uniprot.org/uniprotkb/E1BK10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BK10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK10" }, { "id": "SM00181", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 129, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 407, "end_pos": 409 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"https://www.reactome.org/PathwayBrowser/#R-BTA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-BTA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-BTA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-BTA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-BTA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FB32-1", "protein_name": "Shugoshin 2 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"MYTVYFKSWWLLFRMYQFTFMLLLLISTIVSPHPTPILSLPFTLVMEYPVMEVNPVTSGIKRRVKDRIGKTKLNVSLASKIKTKILNNSSIFKISLKHNNRALAQALSREKENSRRITTEKMLLQKEVEKLNFENTFLRLKLNNLNKKLIEIESLVNNNLITAIEMSSLSEFHQSSFLSASKKKRISKQCKSVHLPFARVPLTSENEDDDDGSDDDGDKWKTDCNIRITSKTADTTSSGSRQSFSLHQCNLEVLLPKKENQNTCDSGYSEHTSSVEVLPKEGRDDSDQSLKSSLTEMKTAPSPSFIREKPSLNVTERRKRGSSTADNLYVTDFDYQQITSPGFNRNNKISGCASETRSNLQKNTQCLPDLPSKSASNPNAKHMETVQKTDDFQLQNTLYENADMDLTASEVSKIITISKSNKNQSMKKTDCGKETFRKVKDASSEKKKERSKRKCKGSSEMGAEGKMENGPERGSVVLDGRGDAEDLNCIPSTEQLPQATMLKKITLQSSWDQGNTQNTKRNRTRRTGEQEQGSFSQCAVKLLQDSKFDQCQDTLHCNRNKPSRQTFVIHKSEKDNLFPNQKDEETSNENPEDANEFHRANVSTKDNENVCDYETKTTLDLEKYVSAQQSQSKINKPKQKINRRTKIISSMNQIYEDNDNDKDIRVLEKHNFPLQTQANKETTYGNVEASKEFEAPPLFTRNNENLHDCQTQNVLDLHKQIANMHPAQNESQISKIPRKKVNRKTEIISISVVNHFSNDRGVHCSEKDESFLLKKDKDIPETLKDLSNFEVPAFCNKDSEKLCDYKTQTLLGLRKDDHNMQPSCYNDLKVDKKPRQKVHRKTEIISKTKQIHENDGESVHDPLNKKLCQKVGKSEIVSQMNQIHENINEDMNGFKSYINDQDVMSYCGEINNNKEESCDPIPDACVLVKKHRKKLPGGAKNILTGGKNRHILQLTDSSQKSVALESGVYHDSEGTDSVPGELTNLPKSQRQSTVSTLEDALSMGVEKGESCPAKRVKKLTSKSKKRKTSIDLSSDTHGVVEITSNTDHIQQTDKENYLENEKIAKSKTDFCTKVLKPLSQICSSNIKISSLNDMCESSVPLSICSSKNLMMEENASLESTCIFQVDDDACEKIKERTHKSCRTTEASGIDRGTFQDMMDSSSASSNTENASEGQSAQLMRRKRQCAPLNLREPNLVSKMRR", "length": 1201 }, "evidence": [ { "id": "E1BLA0", "url": "https://omabrowser.org/oma/group/E1BLA0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZWI4-1", "protein_name": "Shugoshin 2", "gene_name": "Sgo2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"length": 1163 }, "evidence": [ { "id": "E1BLA0", "url": "https://omabrowser.org/oma/group/E1BLA0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q562F6-1", "protein_name": "Shugoshin 2", "gene_name": "SGO2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MECPVMETGSLFTSGIKRHLKDKRISKTTKLNVSLASKIKTKILNNSSIFKISLKHNNRALAQALSREKENSRRITTEKMLLQKEVEKLNFENTFLRLKLNNLNKKLIDIEALMNNNLITAIEMSSLSEFHQSSFLLSASKKKRISKQCKLMRLPFARVPLTSNDDEDEDKEKMQCDNNIKSKTLPDIPSSGSTTQPLSTQDNSEVLFLKENNQNVYGLDDSEHISSIVDVPPRESHSHSDQSSKTSLMSEMRNAQSIGRRWEKPSPSNVTERKKRGSSWESNNLSADTPCATVLDKQHISSPELNCNNEINGHTNETNTEMQRNKQDLPGLSSESAREPNAECMNQIEDNDDFQLQKTVYDADMDLTASEVSKIVTVSTGIKKKSNKKTNEHGMKTFRKVKDSSSEKKRERSKRQFKNSSDVDIGEKIENRTERSDVLDGKRGAEDPGFIFNNEQLAQMNEQLAQVNELKKMTLQTGFEQGDRENVLCNKKEKRITNEQEETYSLSQSSGKFHQESKFDKGQNSLTCNKSKASRQTFVIHKLEKDNLLPNQKDKVTIYENLDVTNEFHTANLSTKDNGNLCDYGTHNILDLKKYVTDIQPSEQNESNINKLRKKVNRKTEIISGMNHMYEDNDKDVVHGLKKGNFFFKTQEDKEPISENIEVSKELQIPALSTRDNENQCDYRTQNVLGLQKQITNMYPVQQNESKVNKKLRQKVNRKTEIISEVNHLDNDKSIEYTVKSHSLFLTQKDKEIIPGNLEDPSEFETPALSTKDSGNLYDSEIQNVLGVKHGHDMQPACQNDSKIGKKPRLNVCQKSEIIPETNQIYENDNKGVHDLEKDNFFSLTPKDKETISENLQVTNEFQTVDLLIKDNGNLCDYDTQNILELKKYVTDRKSAEQNESKINKLRNKVNWKTEIISEMNQIYEDNDKDAHVQESYTKDLDFKVNKSKQKLECQDIINKHYMEVNSNEKESCDQILDSYKVVKKRKKESSCKAKNILTKAKNKLASQLTESSQTSISLESDLKHITSEADSDPGNPVELCKTQKQSTTTLNKKDLPFVEEIKEGECQVKKVNKMTSKSKKRKTSIDPSPESHEVMERILDSVQGKSTVSEQADKENNLENEKMVKNKPDFYTKAFRSLSEIHSPNIQDSSFDSVREGLVPLSVSSGKNVIIKENFALECSPAFQVSDDEHEKMNKMKFKVNRRTQKSGIGDRPLQDLSNTSFVSNNTAESENKSEDLSSERTSRRRRCTPFYFKEPSLRDKMRR", "length": 1265 }, "evidence": [ { "id": "E1BLA0", "url": "https://omabrowser.org/oma/group/E1BLA0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TSY8-1", "protein_name": "Shugoshin 2A", "gene_name": "Sgo2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEYPGIKVDTVTSGIQRRVKGRIAKTNLNVSLASKIKAKILNNSSIFKISLKHNNRALARALSKEKENSRRITTEKMQLQKEVEKLNFENTFLRLKLNTLNKKLVEIESHVSNDLLTAIEISSLSEFHQGSFLLSATKKQRNSKQCKPAHLPYARVLLTSENDDDDGADDKWQTKCNNRTISKTSPDSTSSVSRQPSSLHQCNLKAFPPKEDNQKTCGSGHLEHTSSVDILPNESHSDQSPKSSLSEMKTAPSPSLRREKLSHGNVTMRKKCVSSTPDILYVTDLDHQPTSSPGSNWNNEIHGHTNETSNNTQRNAECFLDLPSESSSEPDAKRMELVQKNTDSFHFQKTVYDAADMELTATDIGKIVAVSKSKKNQNKKKADCRKETFRKVKGASSDKKRESSKRECKDGSEVGAEEEADAARAERGAGVLDGRGDSEEPNCISSTEQPSQVNTQKKRTLQNSSDQENIQNTKRRQTYTTDEQEETNPFSRHSVKFLQDGKFDLCQKTLHHNLSKPSRQTFVIRKSEKDNLFPNQEDKDTISENLEVTNEFHIDDLSIEANENVCDHETQTMLDLKKSVSAQQNQTKINKTKQKINRRTKIISVMSQVYEDNDKDIHVLEKDNFPFHTQANKETTSGNLESSKEFESPLLFTRDNGSLRDCKTQNVLDLHKQIPDLYPDRNESQISKIPRQKVNRKTEVISGVKCFSNDQGVHCSEKDKSLLLQKDKDFPGTLKDLSEFDTPAFCNKDSAKSCDYKSEMLLGLKKHDPNMQPACQDDSKAGKKLRQKVNRKTEIISKITQIHENDRGSTHDSLNKKLCQKVNISKIISQMNQIYETINEDGNGFKSSIKDCEDIKSCDFGEINSNKKENYDPIQDPCTLVKKTKRKGSCKAGSSLAGAKNRCGLQLTDSSQVQSVPLDSGLRHHPNEADSGPGEQTNLPKMQKQSAGRSLGDAFSVSLGKEGSRPAKAVSKMTPKSKKRKLPLGCSPETHGTVEITPNTDLAKAVDSQQTEKENYLEKEKIAKRKPDFCTKVLKPLSETCSSNIKNSSLDSMCKSSLPLSISSRKTLMLEESSSLESTCIFQVGDAAHEKITTGTRNPHHRTQKSTPGSRTSLVLVDTSSVSDTNPANPENESEGQSSHPMRRKRQCVPLNLTEPSLRSKMRR", "length": 1164 }, "evidence": [ { "id": "E1BLA0", "url": "https://omabrowser.org/oma/group/E1BLA0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitotic cohesin complex", "id": "GO:0030892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030892", "evidence": [ { "database": "UniProtKB", "id": "E1BLA0", "url": "https://www.uniprot.org/uniprotkb/E1BLA0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BLA0", "url": "https://www.uniprot.org/uniprotkb/E1BLA0" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "E1BLA0", "url": "https://www.uniprot.org/uniprotkb/E1BLA0" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "E1BLA0", "url": "https://www.uniprot.org/uniprotkb/E1BLA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "E1BLA0", "url": "https://www.uniprot.org/uniprotkb/E1BLA0" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E1BLA0", "url": "https://www.uniprot.org/uniprotkb/E1BLA0" } ], "pmid": "" }, { "name": "homologous chromosome segregation", "id": "GO:0045143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045143", "evidence": [ { "database": "UniProtKB", "id": "E1BLA0", "url": "https://www.uniprot.org/uniprotkb/E1BLA0" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion, centromeric", "id": "GO:0071962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071962", "evidence": [ { "database": "UniProtKB", "id": "E1BLA0", "url": "https://www.uniprot.org/uniprotkb/E1BLA0" } ], "pmid": "" }, { "name": "meiotic sister chromatid cohesion", "id": "GO:0051177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051177", "evidence": [ { "database": "UniProtKB", "id": "E1BLA0", "url": "https://www.uniprot.org/uniprotkb/E1BLA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1293, "end_pos": 1295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 694, "end_pos": 696, "annotation": "n_glycosylation_sequon" }, { "start_pos": 699, "end_pos": 701, "annotation": "n_glycosylation_sequon" }, { "start_pos": 721, "end_pos": 723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" }, { "start_pos": 975, "end_pos": 977, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1293, "end_pos": 1295 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 314, "end_pos": 316 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 46, "end_pos": 48 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 635, "end_pos": 637 }, { "start_pos": 694, "end_pos": 696 }, { "start_pos": 699, "end_pos": 701 }, { "start_pos": 721, "end_pos": 723 }, { "start_pos": 781, "end_pos": 783 }, { "start_pos": 975, "end_pos": 977 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIX7-1", "uniprot_ac": "E1BIX7", "uniprot_id": "E1BIX7_BOVIN", "mass": { "chemical_mass": 76323.0, "monoisotopic_mass": 76323.0 }, "refseq": { "ac": "NP_001179284", "name": "G-protein-signaling modulator 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179284" }, "gene_names": [ { "name": "GPSM2", "type": "recommended", "evidence": [ { "id": "E1BIX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIX7" } ] }, { "name": "GPSM2", "type": "synonym", "evidence": [ { "id": "NP_001179284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179284" } ] } ], "protein_names": [ { "name": "G protein signaling modulator 2", "type": "synonym", "evidence": [ { "id": "E1BIX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIX7/entry#names_and_taxonomy" } ] }, { "name": "G-protein signaling modulator 2 (AGS3-like, C. elegans)", "type": "synonym", "evidence": [ { "id": "NP_001179284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179284" } ] }, { "name": "G-protein-signaling modulator 2", "type": "synonym", "evidence": [ { "id": "NP_001179284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179284" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIX7", "url": "https://www.uniprot.org/uniprotkb/E1BIX7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPSM2", "url": "https://www.uniprot.org/uniprotkb/E1BIX7", "locus": { "chromosome": "3", "start_pos": 34431970, "end_pos": 34485343, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017124", "url": "https://www.ensembl.org/id/ENSBTAG00000017124" } ] } } ], "crossref": [ { "id": "E1BIX7", "url": "https://alphafold.ebi.ac.uk/entry/E1BIX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017124", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017124", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "513654", "url": "https://www.ncbi.nlm.nih.gov/gene/513654", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513654", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513654", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQSVLGH", "url": "https://omabrowser.org/oma/group/NQSVLGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIX7", "url": "https://www.orthodb.org/?gene=E1BIX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45954", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45954", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45954:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45954:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179284", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179284", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SM38", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SM38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SM38-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SM38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPR7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPR7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIX7", "url": "https://www.uniprot.org/uniprotkb/E1BIX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIX7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEENLINMREDHSFHVRYRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQEVGEFPEEVRNALQAAVDYYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAIEAQSCYSLGNTYTLLQDYEKAIDYHLKHLTIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDRSGELTARLNLSDLQMVLGLSYSTNNSMISENIEIDNSLHGARPKFGRRHSMENMELMKLTPEKVQNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDTSNSIDHRIPNSQRKISADSIGDEGFFDLLSRFQSNRMDDQRCCLQEKNSTSAAAAASSTPLKRMLKTPPVSVLSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTQNNSQSVLGHLMTNDNKEPEEDFFDILVKCQGSRLDDQRCAPPPAATKGPTVPDEDFLSLILRSQAKRMDEQRALLQRDQNRDTEFGLKDLLQSNALLELENSGKK", "length": 681, "header": "tr|E1BIX7-1|E1BIX7_BOVIN Isoform 1 of G protein signaling modulator 2 OS=Bos taurus OX=9913 GN=GPSM2 PE=3 SV=2 CANONICAL=E1BIX7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SM38-1", "url": "https://www.uniprot.org/uniprotkb/E1BIX7/entry#A0AAA9SM38-1", "sequence": { "sequence": "MVPQVTTVCLSPWVKPCAIIRILSYGDIMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQEVGEFPEEVRNALQAAVDYYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAIEAQSCYSLGNTYTLLQDYEKAIDYHLKHLTIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDRSGELTARLNLSDLQMVLGLSYSTNNSMISENIEIDNSLHGARPKFGRRHSMENMELMKLTPEKVQNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDTSNSIDHRIPNSQRKISADSIGDEGFFDLLSRFQSNRMDDQRCCLQEKNSTSAAAAASSTPLKRMLKTPPVSVLSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTQNNSQSVLGHLMTNDNKEPEEDFFDILVKCQGSRLDDQRCAPPPAATKGPTVPDEDFLSLILRSQAKRMDEQRALLQRDQNRDTEFGLKDLLQSNALLELENSGKK", "length": 690, "header": "tr|A0AAA9SM38-1|E1BIX7_BOVIN Computationally mapped isoform of G protein signaling modulator 2 OS=Bos taurus OX=9913 GN=GPSM2 PE=3 SV=1 CANONICAL=E1BIX7-1" }, "locus": { "chromosome": "3", "start_pos": 34461739, "end_pos": 34432562, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129165.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129165.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084957.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084957.1" } ] } }, { "isoform_ac": "A0AAA9SPR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIX7/entry#A0AAA9SPR7-1", "sequence": { "sequence": "MEENLINMREDHSFHVRYRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQEVGEFPEEVRNALQAAVDYYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAIEAQSCYSLGNTYTLLQDYEKAIDYHLKHLTIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDRSGELTARLNLSDLQMVLGLSYSTNNSMISENIEIDNSLHGARPKFGRRHSMENMELMKLTPEKVQNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDTSNSIDHRIPNSQRKISADSIGDEGFFDLLSRFQSNRMDDQRCCLQEKNSTSAAAAASSTPLKRMLKRVQIR", "length": 538, "header": "tr|A0AAA9SPR7-1|E1BIX7_BOVIN Computationally mapped isoform of G protein signaling modulator 2 OS=Bos taurus OX=9913 GN=GPSM2 PE=3 SV=1 CANONICAL=E1BIX7-1" }, "locus": { "chromosome": "3", "start_pos": 34466997, "end_pos": 34432773, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103974.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103974.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088289.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088289.1" } ] } }, { "isoform_ac": "E1BIX7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIX7/entry#E1BIX7-1", "sequence": { "sequence": "MEENLINMREDHSFHVRYRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQEVGEFPEEVRNALQAAVDYYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAIEAQSCYSLGNTYTLLQDYEKAIDYHLKHLTIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDRSGELTARLNLSDLQMVLGLSYSTNNSMISENIEIDNSLHGARPKFGRRHSMENMELMKLTPEKVQNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDTSNSIDHRIPNSQRKISADSIGDEGFFDLLSRFQSNRMDDQRCCLQEKNSTSAAAAASSTPLKRMLKTPPVSVLSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTQNNSQSVLGHLMTNDNKEPEEDFFDILVKCQGSRLDDQRCAPPPAATKGPTVPDEDFLSLILRSQAKRMDEQRALLQRDQNRDTEFGLKDLLQSNALLELENSGKK", "length": 681, "header": "tr|E1BIX7-1|E1BIX7_BOVIN Isoform 1 of G protein signaling modulator 2 OS=Bos taurus OX=9913 GN=GPSM2 PE=3 SV=2 CANONICAL=E1BIX7-1" }, "locus": { "chromosome": "3", "start_pos": 34466997, "end_pos": 34432562, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022762.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022762.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022762.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022762.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 626, "start_aa": "Thr", "end_pos": 626, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr626", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:513654", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513654", "resource": "KEGG Pathway" }, { "id": "R-BTA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AGM3-1", "protein_name": "G-protein signaling modulator 2", "gene_name": "Gpsm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPTLLSYTPSLSLRLFLRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQDVGEFPEEVRLALQAAVELYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYRKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIEYHLKHLAIAQELKDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSMMSENIEIDGSLHGAGTKLGRRHSMENMELMKLTPEKVPNWNSEILAKQKPCIAKSSAKLLFVNRLKGKKSKSGSASTKALHHASNPIDHRAPHAQKKVGSDAVGDEGFFDLLRRLQSSRMEDQRCHLQENRTASVAASSATPKMVKAPSASVVSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTEGNNQSVLERLMTNDKKEPDEDFFDILVKCQGSRLDDQRCAPPPAATKGPTVPDEDFFSLILRSQAKRMDEQRVLLQRDPNRDSEFGLKELLQNNALLEFKHSGK", "length": 678 }, "evidence": [ { "id": "E1BIX7", "url": "https://omabrowser.org/oma/group/E1BIX7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YCV2-1", "protein_name": "G protein signaling modulator 2", "gene_name": "GPSM2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHFFRTRDNWTKYCIQSDRYLFLLNLCRMEASCLELALEGERLCKAGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHEYAKALEYHHHDLTLARTIGDLVGEAKASGNLGNTLKVLGNFEEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHSKGKNVACAGTHDPGELPEDVKNALQKAANYYEENLTIVTELGDRAAQGRAFGNLGNTHYLLGNFRSAVLAHEQRLLIAKEFGDRSAERRAYSNLGNAYIFLGEFETASEYYKRTLQLARQLKDRAVEAQACYSLGNTYTLLQDYEKAIDYHLKHLVIAQELNDKIGEGRACWSLGNAYTALGNHDQAMHFAERHLEISREVGDRSGELTARLNLSDLQMVLGLSYSTNTSMMSESHAVDNSLNGTRPRVGRRHSMENMELMKLTPEKVQSWNSEILAKQKPLIAKPSAKLHFVNRLKGKKYKNGTASKVLQDASNSIDSRLPSAQRRNSRETVADEGFFDLLSRFQSNRMDDQRCHFQEKNRFSAASVATSSTPPKTIQKSFSASVVSPHTDEFLDLLASSQSRRLDDQRASFSNLPGLRLNHRTSPSVLGHLMASNNRELDEDFFDILIKCQGSRLDDQRCAPPSSAKGPTVPDEDFFSLIVRSQAKRMDEQRVHLPSAIKGPSSS", "length": 670 }, "evidence": [ { "id": "E1BIX7", "url": "https://omabrowser.org/oma/group/E1BIX7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7JBF3-1", "protein_name": "G-protein-signaling modulator 1", "gene_name": "Gpsm2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGEPGAGRRRRGAQALRDPGWRWDTERPAGESEALAHVTSRGRALGARAGLPRCPCEARRRGGDRPAGSAVVSSLRPEALTPAAPSRSQEPLAGGRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQDVGEFPEEVRNALQAAVDLYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYRKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSMMSENIELDGSLHGARSKLGRRHSMENMELMKLTPEKVPNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKSSSTTKVLHDASNSIDHHAPNPQKKTSAETIGDEGFFDLLRRFQSNRMDDQRCYLQENCRTSSTAASSTTPKMMKAPSVPVVSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTKNNNQSVLEHLMTNDKKEPDEDFFDILVKCQGSRLDDQRCAPPPATTKGPTVPDEDFFSLILRSQAKRMDEQRVLLQRDPNRDTELGLKELLQNNALLEFKHSGK", "length": 755 }, "evidence": [ { "id": "E1BIX7", "url": "https://omabrowser.org/oma/group/E1BIX7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P81274-1", "protein_name": "G protein-signaling modulator 2", "gene_name": "GPSM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEENLISMREDHSFHVRYRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQDVGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSIMSENTEIDSSLNGVRPKLGRRHSMENMELMKLTPEKVQNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDASNSIDHRIPNSQRKISADTIGDEGFFDLLSRFQSNRMDDQRCCLQEKNCHTASTTTSSTPPKMMLKTSSVPVVSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTQNSQSVLSHLMTNDNKEADEDFFDILVKCQGSRLDDQRCAPPPATTKGPTVPDEDFFSLILRSQGKRMDEQRVLLQRDQNRDTDFGLKDFLQNNALLEFKNSGKKSADH", "length": 684 }, "evidence": [ { "id": "E1BIX7", "url": "https://omabrowser.org/oma/group/E1BIX7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VDU0-1", "protein_name": "G protein-signaling modulator 2", "gene_name": "Gpsm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGNLISMREDHSFHVRYRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQDTGEFPEDVRNALQAAVDLYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSMMSENIEIDGSLHGAGAKLGRRHSMENLELMKLTPEKVPNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKSGSACTKVLQDASNSVDHRAPRSQKKISSDTIGDEGFFDLLRRFQSNRMDDQRCHLQGNCRTTSTAAASATPKLMKAPSVSVVSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTKGNSPSVLERLMTNDKKEPDEDFFDILVKCQGSRLDDQRCAPPSAATKGPTVPDEDFFSLILRSQAKRMDEQRVLLQRDPNRDSEFGLKELLQNNALLEFKHSGK", "length": 679 }, "evidence": [ { "id": "E1BIX7", "url": "https://omabrowser.org/oma/group/E1BIX7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VB22-1", "protein_name": "Partner of inscuteable", "gene_name": "pins", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSLSASAENVSSLGLGSGGGGTTSHDGNSQQGSGSDGGSSMCLELALEGERLCKAGDCRAGVAFFQAAIQAGTEDLRTLSAIYSQLGNAYFYLGDYNKAMQYHKHDLTLAKSMNDRLGEAKSSGNLGNTLKVMGRFDEAAICCERHLTLARQLGDRLSEGRALYNLGNVYHAKGKHLGQRNPGKFGDDVKEALTRAVEFYQENLKLMRDLGDRGAQGRACGNLGNTYYLLGDFQAAIEHHQERLRIAREFGDRAAERRANSNLGNSHIFLGQFEDAAEHYKRTLALAVELGEREVEAQSCYSLGNTYTLLHEFNTAIEYHNRHLAIAQELGDRIGEARACWSLGNAHSAIGGHERALKYAEQHLQLAKELHDPVGESTARVNISDLRKLLGMPDSEPSPTEEEARSTASDHSASGNQSDGSENSQGRMVRVRRQSMEQLDLIKITPDGKRMQEEKLRAQATRKAKDDDFFEMLSRSQSKRMDDQRCSIKVNPAGAPAVATGATRKPLVQQNSLFVDPTNLPGLKSPSSANPSAIGHGPLARSATTTQQPDDDFLDMLMRCQGSRLEEQRSELPRPNVTMDAEAEAPPRSVPEAAVPGAPRGQTGRGATVPDEDFFSLIMKVQSGRMEDQRASIPFRNANNNNNSRSNNNGSAGGAGK", "length": 658 }, "evidence": [ { "id": "E1BIX7", "url": "https://omabrowser.org/oma/group/E1BIX7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of spindle assembly", "id": "GO:1905832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905832", "evidence": [ { "database": "UniProtKB", "id": "E1BIX7", "url": "https://www.uniprot.org/uniprotkb/E1BIX7" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cell cortex", "id": "GO:1904778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904778", "evidence": [ { "database": "UniProtKB", "id": "E1BIX7", "url": "https://www.uniprot.org/uniprotkb/E1BIX7" } ], "pmid": "" }, { "name": "maintenance of centrosome location", "id": "GO:0051661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051661", "evidence": [ { "database": "UniProtKB", "id": "E1BIX7", "url": "https://www.uniprot.org/uniprotkb/E1BIX7" } ], "pmid": "" }, { "name": "regulation of mitotic spindle organization", "id": "GO:0060236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060236", "evidence": [ { "database": "UniProtKB", "id": "E1BIX7", "url": "https://www.uniprot.org/uniprotkb/E1BIX7" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "E1BIX7", "url": "https://www.uniprot.org/uniprotkb/E1BIX7" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "E1BIX7", "url": "https://www.uniprot.org/uniprotkb/E1BIX7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPSAGAAAEEEPPAPRPRRRRSLRRLFGRFLLALGSRSRLGDSPPRPRPQPQSGHGDGDGEGGFEGKDPAAPGSPGEERPPGPQPQLPAGDAARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALRRYRAEPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGAQFQGNAQHDALEFLLWLLDRVHEDLEGSSRGPGSDKLQPEARKTSENLLSPSAPLSMGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRIGLAVPILSTVAALRKMVAEEGGVSPEEVILVELYPSGLQRSFFDEEDLNTIAEGDNVYAFQAPPSPGQEMLSARPSGLLVSPCLAAREGQRLSLPVHNETSVLILFCNLVGSGQQASRFGPPFLVREDRAISWIQLQQCILSKVRYLMKSEVPIQNLGSLFSIRVVGLSLACSYLSPQDSRPLCHWAVDRALHLRRPGGPPHIKLAVEWDVDTKERLFGSPQEERVQDADSVRRQQQAHQQHSCTLDECFQFYTKEEQLAQDDAWRCPHCQALQQGVVKLSLWTLPDILIIHLKRFCQVGERRNKLSTLVKFPLAGLNMAPHVAQRSTSPKAMPGAWPPSWKQPACLPTSYPPDFLYDLYAVCNHHGSLQGGHYTAYCRNSLDGQWYSYDDSMVEPLLEDEVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLLRLGSSNGSTRGSLLSWSSAPGPARPRLPESAFCTNSLPRQEKGGLESRPLARGIQGRSISMKVPTPSRAKQGAFKTMPLRWSFGPREKPLGTSVELVEYLESRRRPRSTSQSIVQLLTGPAGGHQKSHATLSAESEDSRRTSDTVLATAPCPSGHPGHCVVPGNSDGLNAARKLKENSSQDIRLPKQFDLPLTVMSSTEDDGRRARPEGQRTTSCKGSGLTGSSGQAPSPKEGPSAAALPRKSADSRPNSPGKMRANGERRDPETDRFPQGTLTLLRSVFWKKEIRKRDRPEAAPQVAPVSLVSGRRSPAVDGEARSSSPSLRIRESLARGPAGHLERERDIRSAPSSLVLPRKTGRPPRANALGMSQRSVPGEQTSFGTLPKVKYHTLSLRRKKSLPESSF", 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"MDPSAGAAAEEEPPAPRPRRRRSLRRLFGRFLLALGSRSRLGDSPPRPRPQPQSGHGDGDGEGGFEGKDPAAPGSPGEERPPGPQPQLPAGDAARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALRRYRAEPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGAQFQGNAQHDALEFLLWLLDRVHEDLEGSSRGPGSDKVWNKAQGDSQDHSASRVAPAWSDLPDTPCFLQPEARKTSENLLSPSAPLSMGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRIGLAVPILSTVAALRKMVAEEGGVSPEEVILVELYPSGLQRSFFDEEDLNTIAEGDNVYAFQAPPSPGQEMLSARPSGLLVSPCLAAREGQRLSLPVHNETSVLILFCNLVGSGQQASRFGPPFLVREDRAISWIQLQQCILSKVRYLMKSEVPIQNLGSLFSIRVVGLSLACSYLSPQDSRPLCHWAVDRALHLRRPGGPPHIKLAVEWDVDTKERLFGSPQEERVQDADSVRRQQQAHQQHSCTLDECFQFYTKEEQLAQDDAWRCPHCQALQQGVVKLSLWTLPDILIIHLKRFCQVGERRNKLSTLVKFPLAGLNMAPHVAQRSTSPKAMPGAWPPSWKQPACLPTSYPPDFLYDLYAVCNHHGSLQGGHYTAYCRNSLDGQWYSYDDSMVEPLLEDEVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLLRLGSSNGSTRGSLLSWSSAPGPARPRLPESAFCTNSLPRQEKGGLESRPLARGIQGRSISMKVPTPSRAKQGAFKTMPLRWSFGPREKPLGTSVELVEYLESRRRPRSTSQSIVQLLTGPAGGHQKSHATLSAESEDSRRTSDTVLATAPCPSGHPGHCVVPGNSDGLNAARKLKENSSQDIRLPKQFDLPLTVMSSTEDDGRRARPEGQRTTSCKGSGLTGSSGQAPSPKEGPSAAALPRKSADSRPNSPGKMRANGERRDPETDRFPQGTLTLLRSVFWKKEIRKRDRPEAAPQVAPVSLVSGRRSPAVDGEARSSSPSLRIRESLARGPAGHLERERDIRSAPSSLVLPRKTGRPPRANALGMSQRSVPGEQTSFGTLPKVKYHTLSLRRKKSLPESSF", "length": 1168, "header": "tr|A0AAA9SV36-1|E1BKF4_BOVIN Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Bos taurus OX=9913 GN=USP43 PE=4 SV=1 CANONICAL=E1BKF4-1" }, "locus": { "chromosome": "19", "start_pos": 28946568, "end_pos": 28895714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108330.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108330.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088038.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088038.1" } ] } }, { "isoform_ac": "E1BKF4-1", "url": "https://www.uniprot.org/uniprotkb/E1BKF4/entry#E1BKF4-1", "sequence": { "sequence": "MDPSAGAAAEEEPPAPRPRRRRSLRRLFGRFLLALGSRSRLGDSPPRPRPQPQSGHGDGDGEGGFEGKDPAAPGSPGEERPPGPQPQLPAGDAARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALRRYRAEPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGAQFQGNAQHDALEFLLWLLDRVHEDLEGSSRGPGSDKLQPEARKTSENLLSPSAPLSMGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRIGLAVPILSTVAALRKMVAEEGGVSPEEVILVELYPSGLQRSFFDEEDLNTIAEGDNVYAFQAPPSPGQEMLSARPSGLLVSPCLAAREGQRLSLPVHNETSVLILFCNLVGSGQQASRFGPPFLVREDRAISWIQLQQCILSKVRYLMKSEVPIQNLGSLFSIRVVGLSLACSYLSPQDSRPLCHWAVDRALHLRRPGGPPHIKLAVEWDVDTKERLFGSPQEERVQDADSVRRQQQAHQQHSCTLDECFQFYTKEEQLAQDDAWRCPHCQALQQGVVKLSLWTLPDILIIHLKRFCQVGERRNKLSTLVKFPLAGLNMAPHVAQRSTSPKAMPGAWPPSWKQPACLPTSYPPDFLYDLYAVCNHHGSLQGGHYTAYCRNSLDGQWYSYDDSMVEPLLEDEVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLLRLGSSNGSTRGSLLSWSSAPGPARPRLPESAFCTNSLPRQEKGGLESRPLARGIQGRSISMKVPTPSRAKQGAFKTMPLRWSFGPREKPLGTSVELVEYLESRRRPRSTSQSIVQLLTGPAGGHQKSHATLSAESEDSRRTSDTVLATAPCPSGHPGHCVVPGNSDGLNAARKLKENSSQDIRLPKQFDLPLTVMSSTEDDGRRARPEGQRTTSCKGSGLTGSSGQAPSPKEGPSAAALPRKSADSRPNSPGKMRANGERRDPETDRFPQGTLTLLRSVFWKKEIRKRDRPEAAPQVAPVSLVSGRRSPAVDGEARSSSPSLRIRESLARGPAGHLERERDIRSAPSSLVLPRKTGRPPRANALGMSQRSVPGEQTSFGTLPKVKYHTLSLRRKKSLPESSF", "length": 1138, "header": "tr|E1BKF4-1|E1BKF4_BOVIN Isoform 1 of ubiquitinyl hydrolase 1 OS=Bos taurus OX=9913 GN=USP43 PE=4 SV=3 CANONICAL=E1BKF4-1" }, "locus": { "chromosome": "19", "start_pos": 28946568, "end_pos": 28895714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000131.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000131.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000131.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000131.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:506996", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506996", "resource": "KEGG Pathway" }, { "id": "R-BTA-5656169", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZED6-1", "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Usp43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPGVGDALGEGPPAPRPRRRRSLRRLLNRFLLALVSRSRSGDSPPRAPAQPSPYDGDGEGGFACAPGPAPASSGSPGPDRPLGSQPQISSGDGARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAVPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSTHGQGSEQLPPEASKISEDLRSSAAPPSLGPSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRVGLAVPILSTVAALRKMVAEEGGVPAEEVILVELYPNGFQRSFFDEEDLNTIAEGDNVYAFQVPPLPGPGTLAAHPPGLSVSPRLAVRDSQRFSVPLHSENRVLILFCNLVGSGQQASRFGPPFLIREDRTISWAQLQQCILSKVRCLMRNEVSAQDLGTLFSIRVVGLSLACSYLSPQDSRPLCHWAVDRALHLRRPGGPPHVKLAVEWDSSVTERLFGSLQEERVQDADSVWRQQQAHQQPSCTLDECFQSYTKEEQLAQDDAWKCPHCQVLQQGVVKLSLWTLPDILIIHLKRFCQVGERRNKLSTLVKFPLSGLNMAPHVARRSTNSKAGPGPWSSWKQPICLPTTYPLDFLYDLYAVCNHHGSLQGGHYTAYCRNSLDGQWYSYDDSTVEPLREDEVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLMRLGSLNNSTRGSLMSWSSAPCPSVARVPDSPVFTNGVCQQDKGVEAGPLVQGVGGRSISMKVPPTSRSRHGPFKTMPLRWSFGHREKRPGASVELVEYLESRRRPRSTSQSIVPLLTRAAGGDETSASPRSDATLPAKSDNSGRATGQGTNGVPLSSCHLNHHSALGSLDDGLHTARTRTGNASQDIRLPKKFDLPLTVMPSAEDGKHARPEGQKMTTWKGSSQVGSQSSPPSPSTGLLRNFKDNGLGTLPKMKAKAAMEERAPDKDRGQGTFTLLKSVFWKKEHKRAVRTESSPPAPSISLASDRLSPALNEHARGSSPALRIRESPARGLGNHSERDIRSAPSSLHLPRKASRPPRASAAVSSQRTIPGELTSYGTLQRVKYHTLSLGRKKSLPESSF", "length": 1136 }, "evidence": [ { "id": "E1BKF4", "url": "https://omabrowser.org/oma/group/E1BKF4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70EL4-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 43", "gene_name": "USP43", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLGPGDAAGGGPLAPRPRRRRSLRRLFSRFLLALGSRSRPGDSPPRPQPGHCDGDGEGGFACAPGPVPAAPGSPGEERPPGPQPQLQLPAGDGARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSSRGPVSEKLPPEATKTSENCLSPSAQLPLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRVGLAVPILSTVAALRKMVAEEGGVPADEVILVELYPSGFQRSFFDEEDLNTIAEGDNVYAFQVPPSPSQGTLSAHPLGLSASPRLAAREGQRFSLSLHSESKVLILFCNLVGSGQQASRFGPPFLIREDRAVSWAQLQQSILSKVRHLMKSEAPVQNLGSLFSIRVVGLSVACSYLSPKDSRPLCHWAVDRVLHLRRPGGPPHVKLAVEWDSSVKERLFGSLQEERAQDADSVWQQQQAHQQHSCTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRFCQVGERRNKLSTLVKFPLSGLNMAPHVAQRSTSPEAGLGPWPSWKQPDCLPTSYPLDFLYDLYAVCNHHGNLQGGHYTAYCRNSLDGQWYSYDDSTVEPLREDEVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLLRLGSHAGSTRGSLLSWSSAPCPSLPQVPDSPIFTNSLCNQEKGGLEPRRLVRGVKGRSISMKAPTTSRAKQGPFKTMPLRWSFGSKEKPPGASVELVEYLESRRRPRSTSQSIVSLLTGTAGEDEKSASPRSNVALPANSEDGGRAIERGPAGVPCPSAQPNHCLAPGNSDGPNTARKLKENAGQDIKLPRKFDLPLTVMPSVEHEKPARPEGQKAMNWKESFQMGSKSSPPSPYMGFSGNSKDSRRGTSELDRPLQGTLTLLRSVFRKKENRRNERAEVSPQVPPVSLVSGGLSPAMDGQAPGSPPALRIPEGLARGLGSRLERDVWSAPSSLRLPRKASRAPRGSALGMSQRTVPGEQASYGTFQRVKYHTLSLGRKKTLPESSF", "length": 1123 }, "evidence": [ { "id": "E1BKF4", "url": "https://omabrowser.org/oma/group/E1BKF4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BUM9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 43", "gene_name": "Usp43", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPGVGNALGEGPPAPRPRRRRSLRRLLNRFLLALGSRSRSGDSPPRPPAQPSPYDGDGEGGFACAPGPAPASAGSPGPDRPPGSQPQISSGDGARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSAHGLVSEQLPPEVSKISEDLRPSAAPTSLGPSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRVGLAVPILSTVAALRKMVAEEGGVPAEEVILVELYPNGFQRSFFDEEDLNTIAEGDNVYAFQVPPSPGLGTLSAHPSGLSVSPRLPVRDSQRFSGPLHSENRVVFLFCNLVGSGQQASRFGPPFLIREDRTISWAQLQQCILSKVRCLMRSEVSAQDLGTLFSIRVVGLSLACSYLSPKDNRPLCHWAVDRALHLRRPGGPPHVKLAVEWDSSVTERLFGSLQEERVQDADSVWRQQQAHQQPSCTLDECFQSYTKEEQLAQDDAWKCPHCQVLQQGVVKLSLWTLPDILIIHLKRFCQVGERRNKLSTLVKFPLSGLNMAPHVARRSTNSKAGPGPWSSWKQPICLPTTYPLDFLYDLYAVCNHHGSLQGGHYTAYCRNSLDGQWYSYDDSTVEALREDEVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLMRLGSLNNSTRGSLLSWSSAPCPSMARVPDSPVFTNGVCHQDKGGVETRPLVRGVGGRSISMKASPASRSRHGPFKTMPLRWSFGHREKRPGASVELVEYLESRRRPRSTSQSIVPLLTRAAGGEETSASPRSDGTLPAKSEDSGRAIGQGTTGVPLSSCHLNHHPALGSLDDSLHTARTRTGNVSQDIRLPKKFDLPLTVMPSVGDEKPARPEGQKMTPWKGSSQVGSQSSPPSPSTGLLRNFKDSGPGTLPKMKSKAAMEERAPDKDRGQGTFTLLKSVFWKKEHKRTVRTESSPPAPPISLGSDRLSPAAMNEQALRIRESPAKGLGNHMERDIRSAPSSLHLPRKASRPPRASTAGTSQRTIPGEQISYGTLQRVKYHTLSLGRKKSLPESSF", "length": 1132 }, "evidence": [ { "id": "E1BKF4", "url": "https://omabrowser.org/oma/group/E1BKF4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BKF4", "url": "https://www.uniprot.org/uniprotkb/E1BKF4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BKF4", "url": "https://www.uniprot.org/uniprotkb/E1BKF4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "E1BKF4", "url": "https://www.uniprot.org/uniprotkb/E1BKF4" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BKF4", "url": "https://www.uniprot.org/uniprotkb/E1BKF4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "E1BKF4", "url": "https://www.uniprot.org/uniprotkb/E1BKF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" }, { "start_pos": 913, "end_pos": 915, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-5653780", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKF4-1" ], "evidence": [ { "id": "R-BTA-5653780", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5653780" } ] }, { "id": "R-BTA-5653786", "name": "USP43 deISGylates ISG:K164,ISG:K168-PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-BTA-5653665", "R-BTA-5653784" ], "enzyme_list": [ "E1BKF4-1" ], "evidence": [ { "id": "R-BTA-5653786", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5653786" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-5653665", "participant_name": "ISG15 [nucleoplasm]", "crossref": [ { "id": "ENSBTAT00000019573", "database": "ENSEMBL", "url": "" }, { "id": "6JH1", "database": "PDB", "url": "" }, { "id": "ENSBTAG00000014707", "database": "ENSEMBL", "url": "" }, { "id": "30293", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000019573", "database": "ENSEMBL", "url": "" }, { "id": "NP_776791.1", "database": "RefSeq", "url": "" }, { "id": "O02741", "database": "UniProt", "url": "" }, { "id": "9JTC", "database": "PDB", "url": "" } ] }, { "participant_id": "R-BTA-5653784", "participant_name": "USP43 [nucleoplasm]", "crossref": [ { "id": "ENSBTAP00000000131", "database": "ENSEMBL", "url": "" }, { "id": "XP_005220488.1", "database": "RefSeq", "url": "" }, { "id": "E1BKF4", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000000120", "database": "ENSEMBL", "url": "" }, { "id": "36730", "database": "VGNC", "url": "" }, { "id": "ENSBTAT00000000131", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BKF4", "gene_name": "USP43", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "E1BKF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKF4" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "E1BKF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKF4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKF4" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 710, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 393, "end_pos": 395 }, { "start_pos": 742, "end_pos": 744 }, { "start_pos": 913, "end_pos": 915 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJW6-1", "uniprot_ac": "E1BJW6", "uniprot_id": "E1BJW6_BOVIN", "mass": { "chemical_mass": 44158.0, "monoisotopic_mass": 44158.0 }, "refseq": { "ac": "XP_002695173", "name": "napsin-A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695173" }, "gene_names": [ { "name": "NAPSA", "type": "recommended", "evidence": [ { "id": "E1BJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJW6" } ] }, { "name": "NAPSA", "type": "synonym", 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"database": "Ensembl Peptide", "id": "ENSBTAP00000008917.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008917.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539259", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539259", "resource": "KEGG Pathway" }, { "id": "R-BTA-5683826", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5683826", "resource": "Reactome", "description": "Surfactant metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AH87-1", "protein_name": "Napsin-A", "gene_name": "NAPSA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"bta:534344", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534344", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IYCQLPK", "url": "https://omabrowser.org/oma/group/IYCQLPK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIW8", "url": "https://www.orthodb.org/?gene=E1BIW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15379:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15379:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179736", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179736", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TET9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TET9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TET9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TET9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIW8", "url": "https://www.uniprot.org/uniprotkb/E1BIW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIW8-1", "url": "https://www.uniprot.org/uniprotkb/E1BIW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFNTRVFKKQMRQVKNPFGLEITNPSSASITTGITLTTDCLEDSLLTCYWGCSVQKLYEALQKHFYCFRISTPRALEDALYSEYLYQEQYFIKKDSKEEIYCQLPRDTKIEDFGTVPRSRYPLVALLTLADKDDREIYDIISMVSVIHIPDKTYKLSCRILYQYLLLAQGQFHDLKQLFMSANNNSTPSSNSSPEEKNTDRSLLEKAGLSESEVEPPEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQQCPMCRQFVQESFALCSQKEQDKDKLKSL", "length": 332, "header": "tr|E1BIW8-1|E1BIW8_BOVIN Isoform 1 of Cell growth regulator with RING finger domain protein 1 OS=Bos taurus OX=9913 GN=CGRRF1 PE=4 SV=1 CANONICAL=E1BIW8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TET9-1", "url": "https://www.uniprot.org/uniprotkb/E1BIW8/entry#A0AAA9TET9-1", "sequence": { "sequence": "MAESEEELKSRLMKVKVESEKVGLKLNIQKTKIMASGLITSWQIDGETVETVSDFIFLGSKITADGDCSHEIKRRFLLGRKVMTNLDSMFKSRDITLPTKVHLVKAMVFPVVMYGCESWTVKKAERRRINAFELWCWRRLLRVPWTARRSNQSILQEISPGISLEGMMLKLKLQYFGHLMQRVDSLEKTLMLGGIGGRRRRGRQRMRWLDGITDQMDVSLSVLRELVMDRFGWDVPVILRNSEETQFNTRVFKKQMRQVKNPFGLEITNPSSASITTGITLTTDCLEDSLLTCYWGCSVQKLYEALQKHFYCFRISTPRALEDALYSEYLYQEQYFIKKDSKEEIYCQLPRDTKIEDFGTVPRSRYPLVALLTLADKDDREIYDIISMVSVIHIPDKTYKLSCRILYQYLLLAQGQFHDLKQLFMSANNNSTPSSNSSPEEKNTDRSLLEKAGLSESEVEPPEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQQCPMCRQFVQESFALCSQKEQDKDKLKSL", "length": 527, "header": "tr|A0AAA9TET9-1|E1BIW8_BOVIN Computationally mapped isoform of Cell growth regulator with RING finger domain protein 1 OS=Bos taurus OX=9913 GN=CGRRF1 PE=4 SV=2 CANONICAL=E1BIW8-1" }, "locus": { "chromosome": "10", "start_pos": 67041607, "end_pos": 67020576, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130320.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130320.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095340.2", "url": "https://www.ensembl.org/id/ENSBTAP00000095340.2" } ] } }, { "isoform_ac": "E1BIW8-1", "url": "https://www.uniprot.org/uniprotkb/E1BIW8/entry#E1BIW8-1", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFNTRVFKKQMRQVKNPFGLEITNPSSASITTGITLTTDCLEDSLLTCYWGCSVQKLYEALQKHFYCFRISTPRALEDALYSEYLYQEQYFIKKDSKEEIYCQLPRDTKIEDFGTVPRSRYPLVALLTLADKDDREIYDIISMVSVIHIPDKTYKLSCRILYQYLLLAQGQFHDLKQLFMSANNNSTPSSNSSPEEKNTDRSLLEKAGLSESEVEPPEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQQCPMCRQFVQESFALCSQKEQDKDKLKSL", "length": 332, "header": "tr|E1BIW8-1|E1BIW8_BOVIN Isoform 1 of Cell growth regulator with RING finger domain protein 1 OS=Bos taurus OX=9913 GN=CGRRF1 PE=4 SV=1 CANONICAL=E1BIW8-1" }, "locus": { "chromosome": "10", "start_pos": 67041607, "end_pos": 67014730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022778.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022778.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022778.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022778.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 237, "start_aa": "Thr", "end_pos": 237, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr237", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:534344", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534344", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MGK4-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "Cgrrf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEEIQFSTRAFKKQMRQVKNPFGLEITNSSSASLAAGVTLTTDCLEDSRLTCFWGCSVQRLYEALQKHRYCFRISTPQALEEALYSDYLHREQYFIKKHSKEEIYCQLPRDTEIEDFGPVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLPCRILYQYLLLAQGQFYDLKQLFMSANSSPSPSSKPSPADRNAEQSLLEKAGLAGSEVEPVEESSKDCVVCQNGGVNWVLLPCRHACLCDSCVCYFKQCPMCRQFVQESFALCGQKEPDKDMLETS", "length": 332 }, "evidence": [ { "id": "E1BIW8", "url": "https://omabrowser.org/oma/group/E1BIW8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0Z858-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "CGRRF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYITVVFVCFLVTSGLVLGWFGLGVPVILRNSEGTESSTRVLKKRMRQVKNPFGLEISHPDTASVTRGITLIPDCLEDCVLTCYWGCNVQKLHEALQKHVYCFRINTPQALEDALYDEYLYRQQYFIKKNDKEEKYCQLPEDAQVVDFGPVPRLCYPLIALLTLADEEDREIYDIISMVSVIHVPDESYRLSCRILYQYLLLAQGQYHDLKQLFMSANSTTPPSCGTSPDERSTDRSLLEKAGLAEDEPELHEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCIKYFQQCPMCRQFVQESFPLCSKKEQDEDESTQILQDVHPGRVF", "length": 342 }, "evidence": [ { "id": "E1BIW8", "url": "https://omabrowser.org/oma/group/E1BIW8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LCB8-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "CGRRF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFNTRVFKKQMRQVKNPFGLEITNPSSASITTGITLRTDCLEDSLLTCYWGCSVQRLYEALQKHFYCFRISTPRALDDALYSEYLYQEQYFIKKDSKEEIYCQLPRENKIEDFGMVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLSCRILYQYLLLAQGQFHDLKQLFMSANNNSTPSSNSSPEGKNTDQSLMEKAGLSESEVEPLEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQQCPMCRQFVQESFALCSQKEQDKDKLKSL", "length": 332 }, "evidence": [ { "id": "E1BIW8", "url": "https://omabrowser.org/oma/group/E1BIW8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97587-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "Cgrrf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIATTGLVLGWLGWDVPVILRNSEETQFSTRAFKKQMRQVKNPFGLEITNSSAASLATGVTLTTDCLEDSRLTCYWGCSVQKLYEALQKHVYCFRISTPQALEEALYSDYLHREQYFIKKHSKEEIYCQLPSSTGVEDFGPVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLPCRILYQYLILAQGQFYDLKQLFMSANNSATPSRDQSPADGSVEHSLLEKAGLAGAEVDPVEESSKDCVVCQNGGVNWVLLPCRHACLCDSCVCYFKQCPMCRQFVQESFALCGQKEADKDILETS", "length": 332 }, "evidence": [ { "id": "E1BIW8", "url": "https://omabrowser.org/oma/group/E1BIW8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BMJ7-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "Cgrrf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFSTRAFKKQMRQVKNPFGLEITNSSAASLATGMALRTDCLEDSRLTCYWGCSVQKLYEALQKHAYCFRISTPQALEEALYSDYLHREQYFIKKHSKEEIYCQLPSDTEIEDFGPVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLPCRILYQYLILAQGQFYDLKQLFMSANNSPPPSNDESPEDRSVEQSLLEKVGLAGNDGDPVEESSRDCVVCQNGGVNWVLLPCRHACLCDSCVRYFKQCPMCRQFVQESFALCGQKEPDKDLLETS", "length": 332 }, "evidence": [ { "id": "E1BIW8", "url": "https://omabrowser.org/oma/group/E1BIW8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99675-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "CGRRF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFSTRVFKKQMRQVKNPFGLEITNPSSASITTGITLTTDCLEDSLLTCYWGCSVQKLYEALQKHVYCFRISTPQALEDALYSEYLYQEQYFIKKDSKEEIYCQLPRDTKIEDFGTVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDRTYKLSCRILYQYLLLAQGQFHDLKQLFMSANNNFTPSNNSSSEEKNTDRSLLEKVGLSESEVEPSEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQQCPMCRQFVQESFALCSQKEQDKDKPKTL", "length": 332 }, "evidence": [ { "id": "E1BIW8", "url": "https://omabrowser.org/oma/group/E1BIW8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BIW8", "url": "https://www.uniprot.org/uniprotkb/E1BIW8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BIW8", "url": "https://www.uniprot.org/uniprotkb/E1BIW8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BIW8", "url": "https://www.uniprot.org/uniprotkb/E1BIW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "E1BIW8", "url": "https://www.uniprot.org/uniprotkb/E1BIW8" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "E1BIW8", "url": "https://www.uniprot.org/uniprotkb/E1BIW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIW8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 332, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIW8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIW8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW8" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 274, "end_pos": 309, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 237 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 279, "end_pos": 281 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGU2-1", "uniprot_ac": "E1BGU2", "uniprot_id": "E1BGU2_BOVIN", "mass": { "chemical_mass": 169271.0, "monoisotopic_mass": 169271.0 }, "refseq": {}, "gene_names": [ { "name": "CLASP1", "type": "recommended", "evidence": [ { "id": "E1BGU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGU2" } ] } ], "protein_names": [ { "name": "CLIP-associating protein 1", "type": "recommended", "evidence": [ { "id": "E1BGU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGU2/entry#names_and_taxonomy" } ] }, { "name": "Cytoplasmic linker-associated protein 1", "type": "synonym", "evidence": [ { "id": "E1BGU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGU2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.", "evidence": [ { "database": "UniProtKB", "id": "G3N2Y5", "url": "https://www.uniprot.org/uniprotkb/G3N2Y5#function" }, { "database": "UniProtKB", "id": "ARBA00055763", "url": "https://www.uniprot.org/uniprotkb/ARBA00055763#function" }, { "database": "UniProtKB", "id": "E1BGU2", "url": "https://www.uniprot.org/uniprotkb/E1BGU2#function" }, { "database": "UniProtKB", "id": "A0A3Q1LPZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPZ9#function" }, { "database": "UniProtKB", "id": "A0A3Q1LUB8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGU2", "url": "https://www.uniprot.org/uniprotkb/E1BGU2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CLASP1", "url": "https://www.uniprot.org/uniprotkb/E1BGU2", "locus": { "chromosome": "2", "start_pos": 73072008, "end_pos": 73344983, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019781", "url": "https://www.ensembl.org/id/ENSBTAG00000019781" } ] } } ], "crossref": [ { "id": "ENSBTAG00000019781", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019781", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21567", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21567", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21567:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21567:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12348", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12348", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LPZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUB8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGU2", "url": "https://www.uniprot.org/uniprotkb/E1BGU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGU2-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2Y5", "url": "https://www.uniprot.org/uniprotkb/G3N2Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2Y5-1", "url": "https://www.uniprot.org/uniprotkb/G3N2Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRMEACLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQALLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGTCLCLVATLNASGAHTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPASSRRNVGMGTTRRLGSSSLGSKSSAAKEGAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQTHLKSSDSVVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSASTAGSLQRSRSDIDVNAAASAKSKISSAAGTAPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPADSRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYSGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSTSQGCSRDASRESSRDTSPARGFAPLDRFGLGQAGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWAERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFINSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHPSSRTSPLTSPTNCSHGGLSPSRLWGCNADGLSRHPPPFPQPNSIPTAPSHKTLRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGRKDCDIVSRDGGIASPATEGRGGSEVVEGGRTALDNKTSLLNTQPPRAFPGPRARDYSPYPYSDTISAYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIVQTADYPINLAAIKMQTKVVERIAKESLLQLLADIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", "length": 1540, "header": "tr|E1BGU2-1|E1BGU2_BOVIN Isoform 1 of CLIP-associating protein 1 OS=Bos taurus OX=9913 GN=CLASP1 PE=3 SV=4 CANONICAL=E1BGU2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPZ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU2/entry#A0A3Q1LPZ9-1", "sequence": { "sequence": "MEPRMEACLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQALLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGTCLCLVATLNASGAHTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPASSRRNVGMGTTRRLGSSSLGSKSSAAKEGAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQTHLKSSDSVVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSASTAGSLQRSRSDIDVNAAASAKSKISSAAGTAPFSSAAALPPGSYASLDGTATKAEGRIRTRRQSSGSATNVASTPADSRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYSGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLDRFGLGQAGRIPGSVNAMRVLSTSTDLEAAVADALLLGDSRSKKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWAERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFINSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHPSSRTSPLTSPTNCSHGGLSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGRKDCDIVSRDGGIASPATEGRGGSEVVEGGRTALDNKTSLLNTQPPRAFPGPRARDYSPYPYSDTISAYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIVQTADYPINLAAIKMQTKVVERIAKESLLQLLADIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", "length": 1480, "header": "tr|A0A3Q1LPZ9-1|E1BGU2_BOVIN Computationally mapped isoform of CLIP-associating protein 1 OS=Bos taurus OX=9913 GN=CLASP1 PE=3 SV=2 CANONICAL=E1BGU2-1" }, "locus": { "chromosome": "2", "start_pos": 73306062, "end_pos": 73074891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073889.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073889.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059030.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059030.2" } ] } }, { "isoform_ac": "A0A3Q1LUB8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU2/entry#A0A3Q1LUB8-1", "sequence": { "sequence": "MEPRMEACLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQALLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGTCLCLVATLNASGAHTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPASSRRNVGMGTTRRLGSSSLGSKSSAAKEGAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQTHLKSSDSVVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSASTAGSLQRSRSDIDVNAAASAKSKISSAAGTAPFSSAAALPPGSYASLESKHMRGDTEPLGLDSGRIRTRRQSSGSATNVASTPADSRGRSRAKVVSQSQPGSRSSSPGKLLGSGYSGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLDRFGLGQAGRIPGSVNAMRVLSTSTDLEAAVADALLLGDSRSKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWAERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFINSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHPSSRTSPLTSPTNCSHGGLSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGRKDCDIVSRDGGIASPATEGRGGSEVVEGGRTALDNKTSLLNTQPPRAFPGPRARDYSPYPYSDTISAYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIVQTADYPINLAAIKMQTKVVERIAKESLLQLLADIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", "length": 1479, "header": "tr|A0A3Q1LUB8-1|E1BGU2_BOVIN Computationally mapped isoform of CLIP-associating protein 1 OS=Bos taurus OX=9913 GN=CLASP1 PE=3 SV=2 CANONICAL=E1BGU2-1" }, "locus": { "chromosome": "2", "start_pos": 73306062, "end_pos": 73074891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082283.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082283.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058811.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058811.2" } ] } }, { "isoform_ac": "E1BGU2-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU2/entry#E1BGU2-1", "sequence": { "sequence": "MEPRMEACLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQALLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGTCLCLVATLNASGAHTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPASSRRNVGMGTTRRLGSSSLGSKSSAAKEGAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQTHLKSSDSVVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSASTAGSLQRSRSDIDVNAAASAKSKISSAAGTAPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPADSRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYSGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSTSQGCSRDASRESSRDTSPARGFAPLDRFGLGQAGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWAERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFINSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHPSSRTSPLTSPTNCSHGGLSPSRLWGCNADGLSRHPPPFPQPNSIPTAPSHKTLRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGRKDCDIVSRDGGIASPATEGRGGSEVVEGGRTALDNKTSLLNTQPPRAFPGPRARDYSPYPYSDTISAYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIVQTADYPINLAAIKMQTKVVERIAKESLLQLLADIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", "length": 1540, "header": "tr|E1BGU2-1|E1BGU2_BOVIN Isoform 1 of CLIP-associating protein 1 OS=Bos taurus OX=9913 GN=CLASP1 PE=3 SV=4 CANONICAL=E1BGU2-1" }, "locus": { "chromosome": "2", "start_pos": 73306062, "end_pos": 73074891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031027.6", "url": "https://www.ensembl.org/id/ENSBTAT00000031027.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030991.6", "url": "https://www.ensembl.org/id/ENSBTAP00000030991.6" } ] } }, { "isoform_ac": "G3N2Y5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU2/entry#G3N2Y5-1", "sequence": { "sequence": "MEPRMEACLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQALLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGTCLCLVATLNASGAHTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPASSRRNVGMGTTRRLGSSSLGSKSSAAKEGAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQTHLKSSDSVVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSASTAGSLQRSRSDIDVNAAASAKSKISSAAGTAPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPADSRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYSGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSTSQGCSRDASRESSRDTSPARGFAPLASRRHSRSTSALATADSVGQSDRFGLGQAGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWAERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFINSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHPSSRTSPLTSPTNCSHGGLSPSRLWGCNADGLSRHPPPFPQPNSIPTAPSHKTLRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGRKDCDIVSRDGGIASPATEGRGGSEVVEGGRTALDNKTSLLNTQPPRAFPGPRARDYSPYPYSDTISAYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIVQTADYPINLAAIKMQTKVVERIAKESLLQLLADIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", 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"https://www.ensembl.org/id/ENSBTAT00000080032.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065012.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065012.2" } ] } }, { "isoform_ac": "E1BHF7-1", "url": "https://www.uniprot.org/uniprotkb/E1BHF7/entry#E1BHF7-1", "sequence": { "sequence": "MAGAPGPLRLALLLLGAVGRAGPRPQGATVSLSETVQKWREYRRQCQRFLTEAPPPAADLFCNRTFDDYACWPDGSPGSFVNVSCPWYLPWASSVLQGHVYRFCTADGLWLHKDNSSLPWRDLSECEDSKRGDRSSPEQQLLSLYVIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDTVLKWMYSTAAQQHQWDGLLSYQESLGCRLVFLLMQYCVAANYYWLLVEGVYLYSLLALSVFSEQRVFRLYLSIGWGVPLLFVIPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLQANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGVLRFVKLFTELSFTSFQGLMVAILYCFVNNEVQMEFRKSWERWQLEHLHVQRENSMKPFKCPTSSLSCGATAGSSVYAASCQTSCS", "length": 463, "header": "tr|E1BHF7-1|E1BHF7_BOVIN Isoform 1 of Glucagon-like peptide 1 receptor OS=Bos taurus OX=9913 GN=GLP1R PE=3 SV=3 CANONICAL=E1BHF7-1" }, "locus": { "chromosome": "23", "start_pos": 12946093, "end_pos": 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Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro).", "evidence": [ { "database": "UniProtKB", "id": "E1BJH1", "url": "https://www.uniprot.org/uniprotkb/E1BJH1#function" }, { "database": "UniProtKB", "id": "ARBA00055550", "url": "https://www.uniprot.org/uniprotkb/ARBA00055550#function" }, { "database": "UniProtKB", "id": "A0A3Q1M752", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M752#function" }, { "database": "UniProtKB", "id": "A0ABI0NXC1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXC1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJH1", "url": "https://www.uniprot.org/uniprotkb/E1BJH1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EDC4", "url": "https://www.uniprot.org/uniprotkb/E1BJH1", "locus": { "chromosome": "18", "start_pos": 35381885, "end_pos": 35370839, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006417", "url": "https://www.ensembl.org/id/ENSBTAG00000006417" } ] } } ], "crossref": [ { "id": "ENSBTAG00000006417", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006417", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "513171", "url": "https://www.ncbi.nlm.nih.gov/gene/513171", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513171", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513171", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TREHMGT", "url": "https://omabrowser.org/oma/group/TREHMGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJH1", "url": "https://www.orthodb.org/?gene=E1BJH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15598", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15598", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15598:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15598:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21289", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21289", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-430039", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-430039", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002694948", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694948", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M752", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M752", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M752-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M752-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXC1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXC1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJH1", "url": "https://www.uniprot.org/uniprotkb/E1BJH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJH1-1", "url": "https://www.uniprot.org/uniprotkb/E1BJH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSCASIDIEDATQHLRDILKLDRPAGGPSAENQRPSNAYNGDLNGLLVPDPLCSGDSASTNKPGFRAMPPINLQEKQVICLLGDDSSTGIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALINGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEEGSPTVALLHEDRAEVWDLDMLRTNHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSPVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPSHSTHEDFPFGESRPELGSEGLGSATHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQIAASPSSSSSSSSSSSSSSSSLTAVSAMSSTSAVDPSLPRPPEELTLSPKLQLDGGLTMSSSSLQASPRGLLPSLLPGPADKLTPKGSGQVPTAASALALELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGASAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLSLDGVPGDGDRHSTPSLLEAALTQEATAPDSQVWPTAPDITRETCSSLAESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDASAEQSDHDDEVASLASAAGNFGTKVPTPRLPAKDWKTKGSPRASPKLKRKGKKDDGDSSLGSRLTEHQVAETPEDWPALIWQQQRELAQLRHSQEELLQRLCAQLEGLQSTVTGHVERALESRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSVRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVESSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVGTLQGATEQMAATVSGSVRAEVQHQLHVAVGSLQEAILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPAAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPGQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLMTPSLP", "length": 1400, "header": "tr|E1BJH1-1|E1BJH1_BOVIN Isoform 1 of Enhancer of mRNA-decapping protein 4 OS=Bos taurus OX=9913 GN=EDC4 PE=3 SV=2 CANONICAL=E1BJH1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M752-1", "url": "https://www.uniprot.org/uniprotkb/E1BJH1/entry#A0A3Q1M752-1", "sequence": { "sequence": "MASSCASIDIEDATQHLRDILKLDRPAGGPSAENQRPSNAYNGDLNGLLVPDPLCSGDSASTNKPGFRAMPPINLQEKQVICLLGDDSSTGIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALINGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEEGSPTVALLHEDRAEVWDLDMLRTNHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSPVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPSHSTHEDFPFGESRPELGSEGLGSATHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQIAASPSSSSSSSSSSSSSSSSLTAVSAMSSTSAVDPSLPRPPEELTLSPKLQLDGGLTMSSSSLQASPRGLLPSLLPGPADKLTPKGSGQVPTAASALALELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGASAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLSLDGVPGDGDRHSTPSLLEAALTQEATAPDSQVWPTAPDITRETCSSLAESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDASAEQSDHDDEVASLASAAGNFGTKVPTPRLPAKDWKTKGSPRASPKLKRKGKKDDGDSSLGSRLTEHQVAETPEDWPALIWQQQRELAQLRHSQEELLQRLCAQLEGLQSTVTGHVERALESRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSVRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVESSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVGTLQGATEQMAATVSGSVRAEVQHQLHVAVGSLQEAILAQAMRSAAGTPVPAAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPGQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLMTPSLP", "length": 1374, "header": "tr|A0A3Q1M752-1|E1BJH1_BOVIN Computationally mapped isoform of Enhancer of mRNA-decapping protein 4 OS=Bos taurus OX=9913 GN=EDC4 PE=3 SV=2 CANONICAL=E1BJH1-1" }, "locus": { "chromosome": "18", "start_pos": 35381562, "end_pos": 35370972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081134.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081134.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064230.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064230.2" } ] } }, { "isoform_ac": "A0ABI0NXC1-1", "url": "https://www.uniprot.org/uniprotkb/E1BJH1/entry#A0ABI0NXC1-1", "sequence": { "sequence": "MPPINLQEKQVICLLGDDSSTGIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALINGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEEGSPTVALLHEDRAEVWDLDMLRTNHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSPVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPSHSTHEDFPFGESRPELGSEGLGSATHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQIAASPSSSSSSSSSSSSSSSSLTAVSAMSSTSAVDPSLPRPPEELTLSPKLQLDGGLTMSSSSLQASPRGLLPSLLPGPADKLTPKGSGQVPTAASALALELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGASAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLSLDGVPGDGDRHSTPSLLEAALTQEATAPDSQVWPTAPDITRETCSSLAESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDASAEQSDHDDEVASLASAAGNFGTKVPTPRLPAKDWKTKGSPRASPKLKRKGKKDDGDSSLGSRLTEHQVAETPEDWPALIWQQQRELAQLRHSQEELLQRLCAQLEGLQSTVTGHVERALESRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSVRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVESSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVGTLQGATEQMAATVSGSVRAEVQHQLHVAVGSLQEAILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPAAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPGQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLMTPSLP", "length": 1331, "header": "tr|A0ABI0NXC1-1|A0ABI0NXC1_BOVIN Computationally mapped isoform of Enhancer of mRNA-decapping protein 4 OS=Bos taurus OX=9913 GN=EDC4 PE=3 SV=1 CANONICAL=E1BJH1-1" }, "locus": { "chromosome": "18", "start_pos": 35381562, "end_pos": 35373492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140510.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140510.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104653.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104653.1" } ] } }, { "isoform_ac": "E1BJH1-1", "url": "https://www.uniprot.org/uniprotkb/E1BJH1/entry#E1BJH1-1", "sequence": { "sequence": "MASSCASIDIEDATQHLRDILKLDRPAGGPSAENQRPSNAYNGDLNGLLVPDPLCSGDSASTNKPGFRAMPPINLQEKQVICLLGDDSSTGIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALINGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEEGSPTVALLHEDRAEVWDLDMLRTNHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSPVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPSHSTHEDFPFGESRPELGSEGLGSATHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQIAASPSSSSSSSSSSSSSSSSLTAVSAMSSTSAVDPSLPRPPEELTLSPKLQLDGGLTMSSSSLQASPRGLLPSLLPGPADKLTPKGSGQVPTAASALALELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGASAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLSLDGVPGDGDRHSTPSLLEAALTQEATAPDSQVWPTAPDITRETCSSLAESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDASAEQSDHDDEVASLASAAGNFGTKVPTPRLPAKDWKTKGSPRASPKLKRKGKKDDGDSSLGSRLTEHQVAETPEDWPALIWQQQRELAQLRHSQEELLQRLCAQLEGLQSTVTGHVERALESRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSVRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVESSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVGTLQGATEQMAATVSGSVRAEVQHQLHVAVGSLQEAILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPAAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPGQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLMTPSLP", "length": 1400, "header": "tr|E1BJH1-1|E1BJH1_BOVIN Isoform 1 of Enhancer of mRNA-decapping protein 4 OS=Bos taurus OX=9913 GN=EDC4 PE=3 SV=2 CANONICAL=E1BJH1-1" }, "locus": { "chromosome": "18", "start_pos": 35381562, "end_pos": 35370972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008416.8", "url": "https://www.ensembl.org/id/ENSBTAT00000008416.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008416.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008416.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 828, "start_aa": "Thr", "end_pos": 828, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr828", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:513171", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513171", "resource": "KEGG Pathway" }, { "id": "R-BTA-430039", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-430039", "resource": "Reactome", "description": "mRNA decay by 5' to 3' exoribonuclease" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P1Q3-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "EDC4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASSNSIDIEDATQHLRDILKLDRPGGSVNENQRPSSSYNGDLNGLLVPDPLVAGDGPALAKPVHRSISLGAVQEKQVICLSGDDSSTCIVISAKDVEIVASSDSSITSKARGSNKVKIQPVARYDWEQKYYYGNLIAVSNSYLAYAIRAASNGSAMVRVLSVSTAERTLLKGFTGGVADLAFAHLNSNQLACLDEAGNLFVWRLAMEEDKIQEEILVNIKRPDGTPLNTSRRIIWCPFIPDDNEENSEEGSQTLALLHEDRAEVWDLDIIRSNNRSWPVEVPNIKEGFIVVKGHSTYLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTVRFSPDIFSSMSILPSLKVCLDLSAEYLILSDVQRKVLYVMELMQNQEKGKAYFSSISEFLLTHPVLSFGIQAVSRCRLRHTEVLPAEEENDNLSIEGAQGAGAVESAAGVLIKLFCVHTKALQDVQIRFQPLHSPDMGASVPSHGSHEEFAFPDHIADLGAEGLGSEKGSVHGSQPDLRRIADLPVPADFLSLSNDAKPKLMTPDAFMTPSTSLQQITVSPGSSVSSLTAVTAMSSTSVTDASMSRPSEDLTVSPKMQLDTSLTLSSSSSSLQTSPRSHSVLIPGLPDKLTPKAPVPVTPGGNSSLALELQEVEPLVVPQASPTRERSPDVISSASTAMSQDIPEIASETLQRSFAAAPPALSAEVLEPSHHADSMASAASALHLLSPRNRHNSEHSHHSLDMPPVEVDRLNAPSLLETALTQENASLDSVVSQPWPAAPDITRETRNSMADSPRDEVEEKHKSSSYHRHSYHLLQHDSQDASAEQSDHDDEVASLASTSGGFGAKASTQRLPMKDWKAKASPRASPKLKRKGKKDDGDVNQSPRSSNNQVTPEFQEELMCVLRSQQRELSELRQNQMELLQRLTDHLDAVQSSLMGHMERVIDSQQEQEQRRLDRALTEGQQRNGQLQEHLSQQLSQTLSSAVCNRLERTVREEMKKTVPQCISKSVDPVAGQLSSTIATKLTAVEGTLKENITKLVKSKNLTDSVVRATADTLQGPIQSAYREAFQSVVLPAFEKSCQSMFQQINDTFKQGTQEYIQQLETHMKNKKAREQEARDPLLNQLRQLISTFQSSTEQLASTIAANIHAEVQHQLHIIVGNLQESILTQVQRVIKGEVSLAMKEQQAAVTSSIVQAMRSAAGTPIPSTHLDFQSQQTHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDTQQVFGQQPCPLSQPVLLSLIQQLSSDLGTRTELKLNYLEEAVMHLDHSDPITRDHMGSVMSQVRQKLFQFLQVEPHNTLSKPARRLMIMLQGLVTPGMT", "length": 1403 }, "evidence": [ { "id": "E1BJH1", "url": "https://omabrowser.org/oma/group/E1BJH1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S2J4-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "EDC4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASSCASIDIEDATQHLRDILKLDRPAGGPSAESQRPSNAYNGDLNGLLVPDPLCSGDGTSANKPGLRAMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHVNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEEGSPTVALLHEDRAEVWDLDMLRSNHNTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGCACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEETDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHPAHEDFAFGESRSELGSEGLGSTTHGSQPDLRRIVELPAPANFLSLSNETKPKLMTPDAFMTPSASLQQIAASPSSSSSSSSSSSSSSSSSLTAVSAMSSTSAVDPSLPRPPEELTLSPKLQLDGGLTISSSSSLQASPRGLLPGLLPGPADKLTPKGPGQVLTAASALSLELQEMEPLGLPQASPTRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLSLDGGPGDGDRHSAPSLLEAALTQETTAPDSQVWPTAPDITRETCSSLAESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDASAEQSDHDDEVASLASAAGGFGTKVPTPRLPAKDWKTKGSPRASPKLKRKGKKDDGDSSMGSRLTEHQVAETPEDWPALIWQQQRELAQLRHSQEELLQRLCTQLEGLQSTVMGHVERALESRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMKESISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQGATEQMAATVSSSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPAAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPGQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLMTPSLP", "length": 1402 }, "evidence": [ { "id": "E1BJH1", "url": "https://omabrowser.org/oma/group/E1BJH1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3UJB9-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "Edc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASCASIDIEDATQHLRDILKLDRPAGGSNAESQRPSSAYNGDLNGLLVPDPLSSGDGNSTNKPGIRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVKGKIQEEILVHIRQPEGTALNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHNTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQDEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGTESSHGAGALESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLSTHTAHEDFTFGESRPELGSEGLASAAHGSQPDLRRIVELPAPADFLSLSSETKPELMTPDAFMTPTASLQQISASPSSSSSSSSSSSSSSSSSSSSLTAVSAVSSSSAMDPSLPRPPEELTLSPKLQLDGSLTLNSSSSSLQASPRSLLPGLLPGPADKLISKGPGQVSTAASALSLDLQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSVPEGLIEPNSMASAASALHLLSPRPRQGPELGSQLGLDGGPGDGDRHSTPSLLEAALTQEVATPDSQVWPTAPDITRETCSTLTESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDTSAEQSDHDDEVASLASASGGFGSKIPTPRLPSKDWKTKGSPRTSPKLKRKSKKDDGDSAVGSRLTEHQVAEPPEDWPALIWQQQRELAELWHNQEELLQRLCAQLEGLQSTVTDHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSVRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVSSSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQATVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRSDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQADPHNSLSKAARRLSLMLHGLVTPSLP", "length": 1406 }, "evidence": [ { "id": "E1BJH1", "url": "https://omabrowser.org/oma/group/E1BJH1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZAV8-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "Edc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASCASIDIEDATQHLRDILKLDRPAGGSNVESQRPSSAYNGDLNGLLVPDPLSSGDGNSTSKPGIRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGDLFVWRLALVKGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQDEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEESDSLGTESSHGAGTLESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLSTHTAHEDFTFGESRPELGSEGLASAPHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPTASLQQISASPSSSSSSSSSSSSSSSSSSSSSLTAVSAVSSSSAMDPSLPSRPPEELTLSPKLQLDGSLTISSSSSLQASPRSLLPGLLPGPADKLIPKGPGQVSSGTSALSLDLQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSVPEGLIEPDSMASAASALHLLSPRPRQGPELSSQLGLDGGPGDGDRHSTPSLLEAALTQEVATSDSQVWPTAPDITRETCSTLTESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDTSAEQSDHDDEVASLASASGGFGSKIPTPRLPAKDWKTKGSPRTSPKLKRKSKKDDGDSAVGSRLTEHQVVEPPEDWPALIWQQQRELAELWHNQEELLQRLCAQLEGLQSTVTDHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLDSHMKSRKAREQEAREPVLAQLRGLVSTLQNATEQMAATVSSSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQATVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRSDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQADPHNSLGKAARRLSLMLHGLVTPSLP", "length": 1407 }, "evidence": [ { "id": "E1BJH1", "url": "https://omabrowser.org/oma/group/E1BJH1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P2E9-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "EDC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASCASIDIEDATQHLRDILKLDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANKTGLRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGYVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPDVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGHACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHTAHEDFTFGESRPELGSEGLGSAAHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQITASPSSSSSGSSSSSSSSSSSLTAVSAMSSTSAVDPSLTRPPEELTLSPKLQLDGSLTMSSSGSLQASPRGLLPGLLPAPADKLTPKGPGQVPTATSALSLELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLGLDGGPGDGDRHNTPSLLEAALTQEASTPDSQVWPTAPDITRETCSTLAESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDASAEQSDHDDEVASLASASGGFGTKVPAPRLPAKDWKTKGSPRTSPKLKRKSKKDDGDAAMGSRLTEHQVAEPPEDWPALIWQQQRELAELRHSQEELLQRLCTQLEGLQSTVTGHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPMAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVAGSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLVTPSLP", "length": 1401 }, "evidence": [ { "id": "E1BJH1", "url": "https://omabrowser.org/oma/group/E1BJH1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VKK1-1", "protein_name": "Enhancer of mRNA-decapping protein 4 homolog", "gene_name": "Ge-1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLIALFALAHLPIFRKTPLSASSSPPPSVHRSPRCGKASTAYHPPPADACISITASAIDAASGMSNSAEQDKPIAANGNAAEPQEIEVIHFQAQEKQCCRVIRSNKTKVLTSGGVHTRGSSKVKLKNIVDYKWERKYYYPGHLVAVHRDGKHLAYAINVNNKATGMEGMVRVCNIATSMRALIKGMSGEVLDLQFAHTDCERILAVIDVSSLFVYKVDQIEGNLLCNLVLKVEDPIANYVPEYDMVSWCPYVCSSSATVPINDDDDENQLLIWSRSSQFQCFQVKMIVSEHGRGKIQPAALESGYLKIEEDSLITCAALSPDGTTVAAACADGLVRFYQIYLFDVRNHRCLHEWKPHDGKKVCSLFFLDNINKPVEESYWQHVITTSDANTEIKLWNCSLWKCLQTINVVASPSSLQPRNFIAGIDRSANYLVLSCLDSLAVYVMQIGSTGGADSENRSSDSEGEGCDTSKRIQNVAEFKLSSGILSFSIVNASMRRVKNSIESYYPIEEPDDFDDDSNSTSALVLHMFVVQAKSLQECQIIYQPCVAEKTERSSLNSKRSQTPEDNLLIKEEPESPNSGTVGAVQLDALFAKSAKRASTGSSSAMVAVAAAAAAAPSAILQDATKEAAKSESPQLSSAYTQQVNLMTPDAFSASGTAAAAAVFVSTSTTTSIGTDSSTTTSGQDRSIDSAVLQTIRMLATVTSKTSENPNAEVLLNLMNNTLIEDREQQKLKEKLDARKKFIAIDRNPERNVAENLASGSSSPSREVQEIMATQDDADAYEAELENLDDDDDDEEEELANSSPLPEAVDGTWPIVKLSSHSAELQNAAQIMSQAVQNTNNGNVPPTLGGGHNNNTSVGSNSNNNTATTLSTSNTSSSNNAGGTCVDSSGTGELNAKMELLIDLVKAQSKQINKLENEVNKLQKQQEAAAALHSKQDTSLEPKNLSQLAYKIEMQLSKLMEQYLKRYENEHKKKLTEFLAARESQNRELRDSVLQVLNQYVMNHFTDIIGNVLNMELQRQLLPRVNANMDQLQAQMQVEIVQKLSVFDKTVKENIAQVCKSKQFLDTFGKSVLIGVQTSLQTAFIESMSSTLIPAYEKSSQNMFKQLHDAFSVGIKDFMVQFNTYLQHMPQPQAGSGNTEEINNKLSMLKQLVESSLHKHRTELTDAMLETQREVKSLEILLARQVQETIRAELRKHMEAQNVAMRSQAATPAPPYDLRDSIKQLLMAGQINKAFHQALLANDLGLVEFTLRHTDSNQAFAPEGCRLEQKVLLSLIQQISADMTNHNELKQRYLNEALLAINMADPITREHAPKVLTELYRNCQQFIKNSPKNSQFSNVRLLMKAIITYRDQLK", "length": 1354 }, "evidence": [ { "id": "E1BJH1", "url": "https://omabrowser.org/oma/group/E1BJH1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BJH1", "url": "https://www.uniprot.org/uniprotkb/E1BJH1" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "E1BJH1", "url": "https://www.uniprot.org/uniprotkb/E1BJH1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BJH1", "url": "https://www.uniprot.org/uniprotkb/E1BJH1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "deadenylation-independent decapping of nuclear-transcribed mRNA", "id": "GO:0031087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031087", "evidence": [ { "database": "UniProtKB", "id": "E1BJH1", "url": "https://www.uniprot.org/uniprotkb/E1BJH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1083, "end_pos": 1085, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1092, "end_pos": 1094, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1137, "end_pos": 1139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH1" }, { "id": "PF21289", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21289" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enhancer of mRNA-decapping protein 4 C-terminal", "eco_id": "ECO_0000259", "start_pos": 1267, "end_pos": 1387, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH1" }, { "id": "PF16529", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16529" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enhancer of mRNA-decapping protein 4 WD40 repeat region", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 442, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 828 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1083, "end_pos": 1085 }, { "start_pos": 1092, "end_pos": 1094 }, { "start_pos": 1137, "end_pos": 1139 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 485, "end_pos": 487 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKZ0-1", "uniprot_ac": "E1BKZ0", "uniprot_id": "E1BKZ0_BOVIN", "mass": { "chemical_mass": 358944.0, "monoisotopic_mass": 358944.0 }, "refseq": {}, "gene_names": [ { "name": "PCNT", "type": "recommended", "evidence": [ { "id": "E1BKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" } ] } ], "protein_names": [ { "name": "Pericentrin", "type": "synonym", "evidence": [ { "id": "E1BKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKZ0", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PCNT", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0", "locus": { "chromosome": "1", "start_pos": 146106892, "end_pos": 146001687, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030670", "url": "https://www.ensembl.org/id/ENSBTAG00000030670" } ] } } ], "crossref": [ { "id": "ENSBTAG00000030670", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030670", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019528", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019528", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EQRGMFT", "url": "https://omabrowser.org/oma/group/EQRGMFT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1H6", "url": "https://www.orthodb.org/?gene=A0A3Q1M1H6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M9D8", "url": "https://www.orthodb.org/?gene=A0A3Q1M9D8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MQR2", "url": "https://www.orthodb.org/?gene=A0A3Q1MQR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BKZ0", "url": "https://www.orthodb.org/?gene=E1BKZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44981:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44981:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10495", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10495", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9646399", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9646399", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M1H6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9D8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQR2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKZ0", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKZ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDDEQEQRRRKVEAGRAKLAHFRQRKTKGDCTHSKKTPAKRKGTTVNAPVTEESPVAAPGNTGPLGGLDIGKNPTCSDTPDGAEAAQLQEPSRERTPPKLDGHCAEQPGVMTKELELEVLRLSLSDMHAARLERTQAHLQREKEAALAELHAELTGRHAQERALLQSRARRELELVREEAAELKEKLQSEIEKNAQMMEILKQDWESERDSCLENLRQELLEKHRSELENLQNQFKKELAQQKAEFEKVFQAKNQAECSLQTQEAQHEASLSKLRADLQLEHCQYLEELERKFRKKEKENQLELERLRASYEELQAQSREEIQCLGAQLESARSSRQELSELREQLLARASHVEELELLKRDLEQQQQQERSRHESELEQLRLYFEEKLREAEQSYQEDLTLLQRRLQEGRDDSLLEAMGTSACLEETSEEERDHLNGLSLQREQLEESLGLRTRLEENHQCQLAAGTSSQDAQQEALEGELPTGPSEEPGQELAREPLLCAQSVALELETEVQAGDMGLETAHRAQLVLLPVELKKEIDLLKVENRNLQEKLQREICLKEDLEKVKQNLVEAHQEELKSAEERIEQIKQELREREAEWKVTSEDLRRGAEEKLTKMLLDLREQVESEKRSMMNRFELRESEMRQLQDQQAAQILDLEGSLVEQQGRLRQLELGLTGDESLRCSHCGRELGCSPAPGAQDQELAILHLKEDCALQLKVAQSRFLEERRAITEKLAAEQDAFLREAQEQHAHELRLLQEGHQRHILSLTAELETRHQAEVDALRSSLERERLALAEAREAELQVKHAADINVLEARHASHLDALRLQYLSELQAVQGRHRQALELLRLDLEERLQKEDMAHHAVLTQVLELLELRCAEEPQPAEDSLRGDGSVEPQEGVRAVRLSMAHKGEFGSERKAALHGKEEIHKLDHEKAHSLYEKEKESLSLQLQEKNNQILQLKDQILSLNREVEERHSELEKLQERRERENQEGTALIAMLKSDVDLSHGERRALQDTLRRLLGLFGETLQTAIALKSRIGERVGLCLEDRSPPTTQPGGQSPPTDPALDDMWAGLDVASLEPDGTVAECAETSSVAEISSHVCESFFLSPERTLDCEQPVRRVFQSLGLAVDGLLEMVLDSARQLEEARQIHSRFEKEFSCKNEETAQVVRKHQELLEQLEAESKAKAQLALELHKAEGIIEGFKEEKAGLQEALGQKEASERGLVGELEGLRQQLQRAARRQAELREENAALCSQTEALAADAREREAALRREVESLTQEQSEARRQADKDRASLLSQMRFLEAELEEQLSHQQACARQAEELAALRQQIDSLDQHLRRQRQFMDEQAVEREREREDFQQEIQRLEEQLRQAARPRSPGLRDSHRAQLDKEVELLEEKLREKSDGLNELILKKELVDRQVLIQGEEIRRLEETNASTTRKLLQLQEELETQRRAVRALQQDKEALQEQQMSNLLQVSALQSRLDEGKCPVPPEGGRPDRAEAQLEAMQGALRQREAEVSDIKEQLENLKDDLVNKNEEILHLNWKLGLQDNSTAASIKELQEENAHLKTLLQNKESEMMHVRESAEAQLARTGSGALSEVVCNRSSEVEELKSIIETLRENQARLQKDNAEEIEQLHEVIEKLQRELPLGGPEAPKAGEGGAMSLQSELLGLPAEGAEAPAVLAGELHAALEAKEALSQRLAEQERQHSQALEALQQRLQAAEEAATRQLAELQPEGVASQIREFEAALHAREAKIAERDLEIQALRREKSTHSAELEAILAAVARFRHALEQQLLAASGEPPELQRLREQCVCLSRQLQALNQRFLKCQKELDERQACGEGGSQGWVPRGKETSCSEELQQDVDGRQLAQALDSRGSDPQSLVKDDLQPAKALPTLTCARPSQQDSVISVLTVCQQQLESELLLVKKEMRLHAEDGGRASGAVKDKGKLLEDCRLQKVDLIAQVKQLQEKLNHLVCSMSFQNIEMEDFKYQQALASPCALEDGLSDGSDNSEETDKSPPIDTFNIIWDLAEVTGNSDSLIRNEPDAPTGEQVTLQDRSLCLQSHLHGCSQDLTHSQGSKPLKNVLRTMGLSPWSSPEVVREDSTLEPLPNLPLTPCSDALSLHSLDTSLWDGTSTHVLQADQSGRLCYPGESAAGTAPKWVGSPLAADGVPSANHHAQRVPVEKDVEDFIITSLDSQEKSRSPPLGLEGKSDGKSGGVEFAEPLSQGSGRLGAPTASPAAPPVTPRDCRRPLDTMKEKEVHPKQVKALLQMVCDESHHILALSEYREPPHILSRSEPSARLECLPLGGQGLLEAVPAPREHPTPGSQKGEKASSNVGLDWKGDFLQTVQEAFEKEWEMLRVELWPQLCGLGPGGCGSLLERLEKVVHEQGDQQERSLEHLCLSDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCTALTSAEARGSRQEHRLRRQVELLAYKVEQEKCIASDLQKTLNEEQEKANNVRKLLVAEQNAVRDLKSELCECRQDNERLLKSLNDVQKEVLQLRSMLDSKESDLQAALQHLEGERMKEQALQSQLEEERLQHMQREGQSAKTLEELRASLEQQCAQSNQLCVVLKHEQTAKDNLRQELQIEASRCEALLAQERGHMSELQRSLEAERDRARELSEALQHERILTERLSRRPQERPAHQALLQKLRAQEEHVRELEVALEAAQRRALEAEAHVHREEVEREQEVSAAPKTPPETLPGTRERPARGRGRVEQDACEDVRTGAELRPSRADTQPWSRWQRDKETLRELELQRQRDEHKIQQLQRTVQELQARVALPNTEPEHLREQQRGLEKVRQQLLCAAGLLTSFINQTVDRTISDWTSSNEKAVASLLHTLETLKSELGTSSSCRKTAAELQIQLVDVLLKDNESLSRALSTVTREKAELCKALSRLERAHRVPRTLQEGCARKRSDRSAWKQDKMVSPGSARHPDPALDAGACSAKMEKLYLRYLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKAAGPRPLTRFRTAVRVVIAVLRLRFLVKKWQQVDGRGALAPGQALRPGEGFLVPRRQQSPPVTRESPPTRDVSSSQARDPVPKASPRRREKSSPPSNPRSERSLTASQDPEHSLTEYIHHLEMIQQRLGGVLPDSTSKKSCCQKMKQ", "length": 3175, "header": "tr|E1BKZ0-1|E1BKZ0_BOVIN Isoform 1 of Pericentrin OS=Bos taurus OX=9913 GN=PCNT PE=4 SV=4 CANONICAL=E1BKZ0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M1H6-1", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0/entry#A0A3Q1M1H6-1", "sequence": { "sequence": "MEDDEQEQRRRKVEAGRAKLAHFRQRKTKGDCTHSKKTPAKRKGTTVNAPVTEESPVAAPGNTGPLGGLDIGKNPTCSDTPDGAEAAQLQEPSRERTPPKLDGHCAEQPGVMTKELELEVLRLSLSDMHAARLERTQAHLQREKEAALAELHAELTGRHAQERALLQSRARRELELVREEAAELKEKLQSEIEKNAQMMEILKQDWESERDSCLENLRQELLEKHRSELENLQNQFKKELAQQKAEFEKVFQAKNQAECSLQTQEAQHEASLSKLRADLQLEHCQYLEELERKFRKKEKENQLELERLRASYEELQAQSREEIQCLGAQLESARSSRQELSELREQLLARASHVEELELLKRDLEQQQQQERSRHESELEQLRLYFEEKLREAEQSYQEDLTLLQRRLQEGRDDSLLEAMGTSACLEETSEEERDHLNGLSLQREQLEESLGLRTRLEENHQCQLAAGTSSQDAQQEALEGELPTGPSEEPGQELAREPLLCAQSVALELETEVQAGDMGLETAHRAQLVLLPVELKKEIDLLKVENRNLQEKLQREICLKEDLEKVKQNLVEAHQEELKSAEERIEQIKQELREREAEWKVTSEDLRRGAEEKLTKMLLDLREQVESEKRSMMNRFELRESEMRQLQDQQAAQILDLEGSLVEQQGRLRQLELGLTGDESLRCSHCGRELGCSPAPGAQDQELAILHLKEDCALQLKVAQSRFLEERRAITEKLAAEQDAFLREAQEQHAHELRLLQEGHQRHILSLTAELETRHQAEVDALRSSLERERLALAEAREAELQVKHAADINVLEARHASHLDALRLQYLSELQAVQGRHRQALELLRLDLEERLQKEDMAHHAVLTQVLELLELRCAEEPQPAEDSLRGDGSVEPQEGVRAVRLSMAHKGEFGSERKAALHGKEEIHKLDHEKAHSLYEKEKESLSLQLQEKNNQILQLKDQILSLNREVEERHSELEKLQERRERENQEGTALIAMLKSDVDLSHGERRALQDTLRRLLGLFGETLQTAIALKSRIGERVGLCLEDRSPPTTQPGGQSPPTDPALDDMWAGLDVASLEPDGTVAECAETSSVAEISSHVCESFFLSPERTLDCEQPVRRVFQSLGLAVDGLLEMVLDSARQLEEARQIHSRFEKEFSCKNEETAQVVRKHQELLEQLEAESKAKAQLALELHKAEGIIEGFKEEKAGLQEALGQKEASERGLVGELEGLRQQLQRAARRQAELREENAALCSQTEALAADAREREAALRREVESLTQEQSEARRQADKDRASLLSQMRFLEAELEEQLSHQQACARQAEELAALRQQIDSLDQHLRRQRQFMDEQAVEREREREDFQQEIQRLEEQLRQAARPRSPGLRDSHVELLEEKLREKSDGLNELILKKELVDRQVLIQGEEIRRLEETNASTTRKLLQLQEELETQRRAVRALQQDKEALQEQQMSNLLQVSALQSRLDEGKCPVPPEGGRPDRAEAQLEAMQGALRQREAEVSDIKEQLENLKDDLVNKNEEILHLNWKLGLQDNSTAASIKELQEENAHLKTLLQNKESEMMHVRESAEAQLARTGSGALSEVVCNRSSEVEELKSIIETLRENQARLQKDNAEEIEQLHEVIEKLQRELPLGGPEAPKAGEGGAMSLQSELLGLPAEGAEAPAVLAGELHAALEAKEALSQRLAEQERQHSQALEALQQRLQAAEEAATRQLAELQPEGVASQIREFEAALHAREAKIAERDLEIQALRREKSTHSAELEAILAAVARFRHALEQQLLAASGEPPELQRLREQCVCLSRQLQALNQRFLKCQKELDERQACGEGGSQGWVPRGKETSCSEELQQDVDGRQLAQALDSRGSDPQSLVKDDLQPAKALPTLTCARPSQQDSVISVLTVCQQQLESELLLVKKEMRLHAEDGGRASGAVKDKGKLLEDCRLQKVDLIAQVKQLQEKLNHLVCSMSFQNIEMEDFKYQQALASPCALEDGLSDGSDNSEETDKSPPIDTFNIIWDLAEVTGNSDSLIRNEPDAPTGEQVTLQDRSLCLQSHLHGCSQDLTHSQGSKPLKNVLRTMGLSPWSSPEVVREDSTLEPLPNLPLTPCSDALSLHSLDTSLWDGTSTHVLQADQSGRLCYPGESAAGTAPKWVGSPLAADGVPSANHHAQRVPVEKDVEDFIITSLDSQEKSRSPPLGLEGKSDGKSQLRSCGRTARLHPVPSEQPSVLGGGVEFAEPLSQGSGRLGAPTASPAAPPVTPRDCRRPLDTMKEKEVHPKQVKALLQMVCDESHHILALSEYREPPHILSRSEPSARLECLPLGGQGLLEAVPAPREHPTPGSQKGEKASSNVGLDWKGDFLQTVQEAFEKEWEMLRVELWPQLCGLGPGGCGSLLERLEKVVHEQGDQQERSLEHLCLSDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCTALTSAEARGSRQEHRLRRQVELLAYKVEQEKCIASDLQKTLNEEQEKANNVRKLLVAEQNAVRDLKSELCECRQDNERLLKSLNDVQKEVLQLRSMLDSKESDLQAALQHLEGERMKEQALQSQLEEERLQHMQREGQSAKTLEELRASLEQQCAQSNQLCVVLKHEQTAKDNLRQELQIEASRCEALLAQERGHMSELQRSLEAERDRARELSEALQHERILTERLSRRPQERPAHQALLQKLRAQEEHVRELEVALEAAQRRALEAEAHVHREEVEREQERELELQRQRDEHKIQQLQRTVQELQARVALPNTEPEHLREQQRGLEKVRQQLLCAAGLLTSFINQTVDRTISDWTSSNEKAVASLLHTLETLKSELGTSSSCRKKTAAELQIQLVDVLLKDNESLSRALSTVTREKAELCKALSRLERAHRVPRTLQEGCARKRSDRSAWKQDKMVSPGSARHPDPALDAGACSAKMEKLYLRYLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKAAGPRPLTRFRTAVRVVIAVLRLRFLVKKWQQVDGRGALAPGQALRPGEGFLVPRRQQSPPVTRESPPTRDVSSSQARDPVPKASPRRREKSSPPSNPRSERSLTASQDPEHSLTEYIHHLEMIQQRLGGVLPDSTSKKSCCQKMKQ", "length": 3132, "header": "tr|A0A3Q1M1H6-1|E1BKZ0_BOVIN Computationally mapped isoform of Pericentrin OS=Bos taurus OX=9913 GN=PCNT PE=4 SV=1 CANONICAL=E1BKZ0-1" }, "locus": { "chromosome": "1", "start_pos": 146105888, "end_pos": 146001886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072914.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072914.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067187.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067187.1" } ] } }, { "isoform_ac": "A0A3Q1M9D8-1", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0/entry#A0A3Q1M9D8-1", "sequence": { "sequence": "MEDDEQEQRRRKVEAGRAKLAHFRQRKTKGDCTHSKKTPAKRKGTTVNAPVTEESPVAAPGNTGPLGGLDIGKNPTCSDTPDGAEAAQLQEPSRERTPPKLDGHCAEQPGVMTKELELEVLRLSLSDMHAARLERTQAHLQREKEAALAELHAELTGRHAQERALLQSRARRELELVREEAAELKEKLQSEIEKNAQMMEILKQDWESERDSCLENLRQELLEKHRSELENLQNQFKKELAQQKAEFEKVFQAKNQAECSLQTQEAQHEASLSKLRADLQLEHCQYLEELERKFRKKEKENQLELERLRASYEELQAQSREEIQCLGAQLESARSSRQELSELREQLLARASHVEELELLKRDLEQQQQQERSRHESELEQLRLYFEEKLREAEQSYQEDLTLLQRRLQEGRDDSLLEAMGTSACLEETSEEERDHLNGLSLQREQLEESLGLRTRLEENHQCQLAAGTSSQDAQQEALEGELPTGPSEEPGQELAREPLLCAQSVALELETEVQAGDMGLETAHRAQLVLLPVELKKEIDLLKVENRNLQEKLQREICLKEDLEKVKQNLVEAHQEELKSAEERIEQIKQELREREAEWKVTSEDLRRGAEEKLTKMLLDLREQVESEKRSMMNRFELRESEMRQLQDQQAAQILDLEGSLVEQQGRLRQLELGLTGDESLRCSHCGRELGCSPAPGAQDQELAILHLKEDCALQLKVAQSRFLEERRAITEKLAAEQDAFLREAQEQHAHELRLLQEGHQRHILSLTAELETRHQAEVDALRSSLERERLALAEAREAELQVKHAADINVLEARHASHLDALRLQYLSELQAVQGRHRQALELLRLDLEERLQKEDMAHHAVLTQVLELLELRCAEEPQPAEDSLRGDGSVEPQEGVRAVRLSMAHKGEFGSERKAALHGKEEIHKLDHEKAHSLYEKEKESLSLQLQEKNNQILQLKDQILSLNREVEERHSELEKLQERRERENQEGTALIAMLKSDVDLSHGERRALQDTLRRLLGLFGETLQTAIALKSRIGERVGLCLEDRSPPTTQPGGQSPPTDPALDDMWAGLDVASLEPDGTVAECAETSSVAEISSHVCESFFLSPERTLDCEQPVRRVFQSLGLAVDGLLEMVLDSARQLEEARQIHSRFEKEFSCKNEETAQVVRKHQELLEQLEAESKAKAQLALELHKAEGIIEGFKEEKAGLQEALGQKEASERGLVGELEGLRQQLQRAARRQAELREENAALCSQTEALAADAREREAALRREVESLTQEQSEARRQADKDRASLLSQMRFLEAELEEQLSHQQACARQAEELAALRQQIDSLDQHLRRQRQFMDEQAVEREREREDFQQEIQRLEEQLRQAARPRSPGLRDSHRAQLDKEVELLEEKLREKSDGLNELILKKELVDRQVLIQGEEIRRLEETNASTTRKLLQLQEELETQRRAVRALQQDKEALQEQQMSNLLQVSALQSRLDEGKCPVPPEGGRPDRAEAQLEAMQGALRQREAEVSDIKEQLENLKDDLVNKNEEILHLNWKLGLQDNSTAASIKELQEENAHLKTLLQNKESEMMHVRESAEAQLARTGSGALSEVVCNRSSEVEELKSIIETLRENQARLQKDNAEEIEQLHEVIEKLQRELPLGGPEAPKAGEGGAMSLQSELLGLPAEGAEAPAVLAGELHAALEAKEALSQRLAEQERQHSQALEALQQRLQAAEEAATRQLAELQPEGVASQIREFEAALHAREAKIAERDLEIQALRREKSTHSAELEAILAAVARFRHALEQQLLAASGEPPELQRLREQCVCLSRQLQALNQRFLKCQKELDERQACGEGGSQGWVPRGKETSCSEELQQDVDGRQLAQALDSRGSDPQSLVKDDLQPAKALPTLTCARPSQQDSVISVLTVCQQQLESELLLVKKEMRLHAEDGGRASGAVKDKGKLLEDCRLQKVDLIAQVKQLQEKLNHLVCSMSFQNIEMEDFKYQQALASPCALEDGLSDGSDNSEETDKSPPIDTFNIIWDLAEVTGNSDSLIRNEPDAPTGEQVTLQDRSLCLQSHLHGCSQDLTHSQGSKPLKNVLRTMGLSPWSSPEVVREDSTLEPLPNLPLTPCSDALSLHSLDTSLWDGTSTHVLQADQSGRLCYPGESAAGTAPKWVGSPLAADGVPSANHHAQRVPVEKDVEDFIITSLDSQEKSRSPPLGLEGKSDGKSQLRSCGRTARLHPVPSEQPSVLGGGVEFAEPLSQGSGRLGAPTASPAAPPVTPRDCRRPLDTMKEKEVHPKQVKALLQMVCDESHHILALSEYREPPHILSRSEPSARLECLPLGGQGLLEAVPAPREHPTPGSQKGEKASSNVGLDWKGDFLQTVQEAFEKEWEMLRVELWPQLCGLGPGGCGSLLERLEKVVHEQGDQQERSLEHLCLSDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCTALTSAEARGSRQEHRLRRQVELLAYKVEQEKCIASDLQKTLNEEQEKANNVRKLLVAEQNAVRDLKSELCECRQDNERLLKSLNDVQKEVLQLRSMLDSKESDLQAALQHLEGERMKEQALQSQLEEERLQHMQREGQSAKTLEELRASLEQQCAQSNQLCVVLKHEQTAKDNLRQELQIEASRCEALLAQERGHMSELQRSLEAERDRARELSEALQHERILTERLSRRPQERPAHQALLQKLRAQEEHVRELEVALEAAQRRALEAEAHVHREEVEREQERELELQRQRDEHKIQQLQRTVQELQARVALPNTEPEHLREQQRGLEKVRQQLLCAAGLLTSFINQTVDRTISDWTSSNEKAVASLLHTLETLKSELGTSSSCRKKTAAELQIQLVDVLLKDNESLSRALSTVTREKAELCKALSRLERAHRVPRTLQEGCARKRSDRSAWKQDKMVSPGSARHPDPALDAGACSAKMEKLYLRYLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKAAGPRPLTRFRTAVRVVIAVLRLRFLVKKWQQVDGRGALAPGQALRPGEGFLVPRRQQSPPVTRESPPTRDVSSSQARDPVPKASPRRREKSSPPSNPRSERSLTASQDPEHSLTEYIHHLEMIQQRLGGVLPDSTSKKSCCQKMKQ", "length": 3139, "header": "tr|A0A3Q1M9D8-1|E1BKZ0_BOVIN Computationally mapped isoform of Pericentrin OS=Bos taurus OX=9913 GN=PCNT PE=4 SV=1 CANONICAL=E1BKZ0-1" }, "locus": { "chromosome": "1", "start_pos": 146105888, "end_pos": 146001886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078760.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078760.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067172.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067172.1" } ] } }, { "isoform_ac": "A0A3Q1MQR2-1", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0/entry#A0A3Q1MQR2-1", "sequence": { "sequence": "MEDDEQEQRRRKVEAGRAKLAHFRQRKTKGDCTHSKKTPAKRKGTTVNAPVTEESPVAAPGNTGPLGGLDIGKNPTCSDTPDGAEAAQLQEPSRERTPPKLDGHCAEQPGVMTKELELEVLRLSLSDMHAARLERTQAHLQREKEAALAELHAELTGRHAQERALLQSRARRELELVREEAAELKEKLQSEIEKNAQMMEILKQDWESERDSCLENLRQELLEKHRSELENLQNQFKKELAQQKAEFEKVFQAKNQAECSLQTQEAQHEASLSKLRADLQLEHCQYLEELERKFRKKEKENQLELERLRASYEELQAQSREEIQCLGAQLESARSSRQELSELREQLLARASHVEELELLKRDLEQQQQQERSRHESELEQLRLYFEEKLREAEQSYQEDLTLLQRRLQEGRDDSLLEAMGTSACLEETSEEERDHLNGLSLQREQLEESLGLRTRLEENHQCQLAAGTSSQDAQQEALEGELPTGPSEEPGQELAREPLLCAQSVALELETEVQAGDMGLETAHRAQLVLLPVELKKEIDLLKVENRNLQEKLQREICLKEDLEKVKQNLVEAHQEELKSAEERIEQIKQELREREAEWKVTSEDLRRGAEEKLTKMLLDLREQVESEKRSMMNRFELRESEMRQLQDQQAAQILDLEGSLVEQQGRLRQLELGLTGDESLRCSHCGRELGCSPAPGAQDQELAILHLKEDCALQLKVAQSRFLEERRAITEKLAAEQDAFLREAQEQHAHELRLLQEGHQRHILSLTAELETRHQAEVDALRSSLERERLALAEAREAELQVKHAADINVLEARHASHLDALRLQYLSELQAVQGRHRQALELLRLDLEERLQKEDMAHHAVLTQVLELLELRCAEEPQPAEDSLRGDGSVEPQEGVRAVRLSMAHKEPEAQCSAPQAGQEEELELLERKPEASLEQQVALLQGEFGSERKAALHGKEEIHKLDHEKAHSLYEKEKESLSLQLQEKNNQILQLKDQILSLNREVEERHSELEKLQERRERENQEGTALIAMLKSDVDLSHGERRALQDTLRRLLGLFGETLQTAIALKSRIGERVGLCLEDRSPPTTQPGGQSPPTDPALDDMWAGLDVASLEPDGTVAECAETSSVAEISSHVCESFFLSPERTLDCEQPVRRVFQSLGLAVDGLLEMVLDSARQLEEARQIHSRFEKEFSCKNEETAQVVRKHQELLEQLEAESKAKAQLALELHKAEGIIEGFKEEKAGLQEALGQKEASERGLVGELEGLRQQLQRAARRQAELREENAALCSQTEALAADAREREAALRREVESLTQEQSEARRQADKDRASLLSQMRFLEAELEEQLSHQQACARQAEELAALRQQIDSLDQHLRRQRQFMDEQAVEREREREDFQQEIQRLEEQLRQAARPRSPGLRDSHRAQLDKEVELLEEKLREKSDGLNELILKKELVDRQVLIQGEEIRRLEETNASTTRKLLQLQEELETQRRAVRALQQDKEALQEQQMSNLLQVSALQSRLDEGKCPVPPEGGRPDRAEAQLEAMQGALRQREAEVSDIKEQLENLKDDLVNKNEEILHLNWKLGLQDNSTAASIKELQEENAHLKTLLQNKESEMMHVRESAEAQLARTGSGALSEVVCNRSSEVEELKSIIETLRENQARLQKDNAEEIEQLHEVIEKLQRELPLGGPEAPKAGEGGAMSLQSELLGLPAEGAEAPAVLAGELHAALEAKEALSQRLAEQERQHSQALEALQQRLQAAEEAATRQLAELQPEGVASQIREFEAALHAREAKIAERDLEIQALRREKSTHSAELEAILAAVARFRHALEQQLLAASGEPPELQRLREQCVCLSRQLQALNQRFLKCQKELDERQACGEGGSQGWVPRGKETSCSEELQQDVDGRQLAQALDSRGSDPQSLVKDDLQPAKALPTLTCARPSQQDSVISVLTVCQQQLESELLLVKKEMRLHAEDGGRASGAVKDKGKLLEDCRLQKVDLIAQVKQLQEKLNHLVCSMSFQNIEMEDFKYQQALASPCALEDGLSDGSDNSEETDKSPPIDTFNIIWDLAEVTGNSDSLIRNEPDAPTGEQVTLQDRSLCLQSHLHGCSQDLTHSQGSKPLKNVLRTMGLSPWSSPEVVREDSTLEPLPNLPLTPCSDALSLHSLDTSLWDGTSTHVLQADQSGRLCYPGESAAGTAPKWVGSPLAADGVPSANHHAQRVPVEKDVEDFIITSLDSQEKSRSPPLGLEGKSDGKSGGVEFAEPLSQGSGRLGAPTASPAAPPVTPRDCRRPLDTMKEKEVHPKQVKALLQMVCDESHHILALSEYREPPHILSRSEPSARLECLPLGGQGLLEAVPAPREHPTPGSQKGEKASSNVGLDWKGDFLQTVQEAFEKEWEMLRVELWPQLCGLGPGGCGSLLERLEKVVHEQGDQQERSLEHLCLSDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCTALTSAEARGSRQEHRLRRQVELLAYKVEQEKCIASDLQKTLNEEQEKANNVRKLLVAEQNAVRDLKSELCECRQDNERLLKSLNDVQKEVLQLRSMLDSKESDLQAALQHLEGERMKEQALQSQLEEERLQHMQREGQSAKTLEELRASLEQQCAQSNQLCVVLKHEQTAKDNLRQELQIEASRCEALLAQERGHMSELQRSLEAERDRARELSEALQHERILTERLSRRPQERPAHQALLQKLRAQEEHVRELEVALEAAQRRALEAEAHVHREEVEREQERELELQRQRDEHKIQQLQRTVQELQARVALPNTEPEHLREQQRGLEKVRQQLLCAAGLLTSFINQTVDRTISDWTSSNEKAVASLLHTLETLKSELGTSSSCRKKTAAELQIQLVDVLLKDNESLSRALSTVTREKAELCKALSRLERAHRVPRTLQEGCARKRSDRSAWKQDKMVSPGSARHPDPALDAGACSAKMEKLYLRYLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKAAGPRPLTRFRTAVRVVIAVLRLRFLVKKWQQVDGRGALAPGQALRPGEGFLVPRRQQSPPVTRESPPTRDVSSSQARDPVPKASPRRREKSSPPSNPRSERSLTASQDPEHSLTEYIHHLEMIQQRLGGVLPDSTSKKSCCQKMKQ", "length": 3152, "header": "tr|A0A3Q1MQR2-1|E1BKZ0_BOVIN Computationally mapped isoform of Pericentrin OS=Bos taurus OX=9913 GN=PCNT PE=4 SV=2 CANONICAL=E1BKZ0-1" }, "locus": { "chromosome": "1", "start_pos": 146105888, "end_pos": 146001886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077625.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077625.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073957.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073957.2" } ] } }, { "isoform_ac": "E1BKZ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0/entry#E1BKZ0-1", "sequence": { "sequence": "MEDDEQEQRRRKVEAGRAKLAHFRQRKTKGDCTHSKKTPAKRKGTTVNAPVTEESPVAAPGNTGPLGGLDIGKNPTCSDTPDGAEAAQLQEPSRERTPPKLDGHCAEQPGVMTKELELEVLRLSLSDMHAARLERTQAHLQREKEAALAELHAELTGRHAQERALLQSRARRELELVREEAAELKEKLQSEIEKNAQMMEILKQDWESERDSCLENLRQELLEKHRSELENLQNQFKKELAQQKAEFEKVFQAKNQAECSLQTQEAQHEASLSKLRADLQLEHCQYLEELERKFRKKEKENQLELERLRASYEELQAQSREEIQCLGAQLESARSSRQELSELREQLLARASHVEELELLKRDLEQQQQQERSRHESELEQLRLYFEEKLREAEQSYQEDLTLLQRRLQEGRDDSLLEAMGTSACLEETSEEERDHLNGLSLQREQLEESLGLRTRLEENHQCQLAAGTSSQDAQQEALEGELPTGPSEEPGQELAREPLLCAQSVALELETEVQAGDMGLETAHRAQLVLLPVELKKEIDLLKVENRNLQEKLQREICLKEDLEKVKQNLVEAHQEELKSAEERIEQIKQELREREAEWKVTSEDLRRGAEEKLTKMLLDLREQVESEKRSMMNRFELRESEMRQLQDQQAAQILDLEGSLVEQQGRLRQLELGLTGDESLRCSHCGRELGCSPAPGAQDQELAILHLKEDCALQLKVAQSRFLEERRAITEKLAAEQDAFLREAQEQHAHELRLLQEGHQRHILSLTAELETRHQAEVDALRSSLERERLALAEAREAELQVKHAADINVLEARHASHLDALRLQYLSELQAVQGRHRQALELLRLDLEERLQKEDMAHHAVLTQVLELLELRCAEEPQPAEDSLRGDGSVEPQEGVRAVRLSMAHKGEFGSERKAALHGKEEIHKLDHEKAHSLYEKEKESLSLQLQEKNNQILQLKDQILSLNREVEERHSELEKLQERRERENQEGTALIAMLKSDVDLSHGERRALQDTLRRLLGLFGETLQTAIALKSRIGERVGLCLEDRSPPTTQPGGQSPPTDPALDDMWAGLDVASLEPDGTVAECAETSSVAEISSHVCESFFLSPERTLDCEQPVRRVFQSLGLAVDGLLEMVLDSARQLEEARQIHSRFEKEFSCKNEETAQVVRKHQELLEQLEAESKAKAQLALELHKAEGIIEGFKEEKAGLQEALGQKEASERGLVGELEGLRQQLQRAARRQAELREENAALCSQTEALAADAREREAALRREVESLTQEQSEARRQADKDRASLLSQMRFLEAELEEQLSHQQACARQAEELAALRQQIDSLDQHLRRQRQFMDEQAVEREREREDFQQEIQRLEEQLRQAARPRSPGLRDSHRAQLDKEVELLEEKLREKSDGLNELILKKELVDRQVLIQGEEIRRLEETNASTTRKLLQLQEELETQRRAVRALQQDKEALQEQQMSNLLQVSALQSRLDEGKCPVPPEGGRPDRAEAQLEAMQGALRQREAEVSDIKEQLENLKDDLVNKNEEILHLNWKLGLQDNSTAASIKELQEENAHLKTLLQNKESEMMHVRESAEAQLARTGSGALSEVVCNRSSEVEELKSIIETLRENQARLQKDNAEEIEQLHEVIEKLQRELPLGGPEAPKAGEGGAMSLQSELLGLPAEGAEAPAVLAGELHAALEAKEALSQRLAEQERQHSQALEALQQRLQAAEEAATRQLAELQPEGVASQIREFEAALHAREAKIAERDLEIQALRREKSTHSAELEAILAAVARFRHALEQQLLAASGEPPELQRLREQCVCLSRQLQALNQRFLKCQKELDERQACGEGGSQGWVPRGKETSCSEELQQDVDGRQLAQALDSRGSDPQSLVKDDLQPAKALPTLTCARPSQQDSVISVLTVCQQQLESELLLVKKEMRLHAEDGGRASGAVKDKGKLLEDCRLQKVDLIAQVKQLQEKLNHLVCSMSFQNIEMEDFKYQQALASPCALEDGLSDGSDNSEETDKSPPIDTFNIIWDLAEVTGNSDSLIRNEPDAPTGEQVTLQDRSLCLQSHLHGCSQDLTHSQGSKPLKNVLRTMGLSPWSSPEVVREDSTLEPLPNLPLTPCSDALSLHSLDTSLWDGTSTHVLQADQSGRLCYPGESAAGTAPKWVGSPLAADGVPSANHHAQRVPVEKDVEDFIITSLDSQEKSRSPPLGLEGKSDGKSGGVEFAEPLSQGSGRLGAPTASPAAPPVTPRDCRRPLDTMKEKEVHPKQVKALLQMVCDESHHILALSEYREPPHILSRSEPSARLECLPLGGQGLLEAVPAPREHPTPGSQKGEKASSNVGLDWKGDFLQTVQEAFEKEWEMLRVELWPQLCGLGPGGCGSLLERLEKVVHEQGDQQERSLEHLCLSDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCTALTSAEARGSRQEHRLRRQVELLAYKVEQEKCIASDLQKTLNEEQEKANNVRKLLVAEQNAVRDLKSELCECRQDNERLLKSLNDVQKEVLQLRSMLDSKESDLQAALQHLEGERMKEQALQSQLEEERLQHMQREGQSAKTLEELRASLEQQCAQSNQLCVVLKHEQTAKDNLRQELQIEASRCEALLAQERGHMSELQRSLEAERDRARELSEALQHERILTERLSRRPQERPAHQALLQKLRAQEEHVRELEVALEAAQRRALEAEAHVHREEVEREQEVSAAPKTPPETLPGTRERPARGRGRVEQDACEDVRTGAELRPSRADTQPWSRWQRDKETLRELELQRQRDEHKIQQLQRTVQELQARVALPNTEPEHLREQQRGLEKVRQQLLCAAGLLTSFINQTVDRTISDWTSSNEKAVASLLHTLETLKSELGTSSSCRKTAAELQIQLVDVLLKDNESLSRALSTVTREKAELCKALSRLERAHRVPRTLQEGCARKRSDRSAWKQDKMVSPGSARHPDPALDAGACSAKMEKLYLRYLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKAAGPRPLTRFRTAVRVVIAVLRLRFLVKKWQQVDGRGALAPGQALRPGEGFLVPRRQQSPPVTRESPPTRDVSSSQARDPVPKASPRRREKSSPPSNPRSERSLTASQDPEHSLTEYIHHLEMIQQRLGGVLPDSTSKKSCCQKMKQ", "length": 3175, "header": "tr|E1BKZ0-1|E1BKZ0_BOVIN Isoform 1 of Pericentrin OS=Bos taurus OX=9913 GN=PCNT PE=4 SV=4 CANONICAL=E1BKZ0-1" }, "locus": { "chromosome": "1", "start_pos": 146105888, "end_pos": 146001886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029328.8", "url": "https://www.ensembl.org/id/ENSBTAT00000029328.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029328.7", "url": "https://www.ensembl.org/id/ENSBTAP00000029328.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2244, "start_aa": "Thr", "end_pos": 2244, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2244", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2323, "start_aa": "Thr", "end_pos": 2323, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2323", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-BTA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-BTA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-BTA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-BTA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-BTA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-BTA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" }, { "id": "R-BTA-9646399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9646399", "resource": "Reactome", "description": "Aggrephagy" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LT86-1", "protein_name": "Pericentrin", "gene_name": "Pcnt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDEQEQRRRKVEAGRAKLANFRQRKTKGDGPNSKKKTAKRKGSAVHASVQEEGSVAPPNSELPQGAAVSERESCGNTLEGTGGAFAAQEQQDCELGVTDLQGQQQPQQQPQPPQTAHSLELEALRLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELMREQHAREKEEMALRNEQETAELKEKFRSEMEKTVQMMETLKQDWESERELCLETLRKELSAKHQSEMEGLQNQFQKELSEQKAELEKIFQAKHEAEVSLKNLEAQHQAAIRKLQEDLRSEHCQYLQDLELRFREKEKAKELELETLQASYEDLKAQSQEEIRHLWSQLESMKTNREEQNGSWEPLLAQASHLEELQHLRSDFAQQQQQERAQHESELEHLRVYFEKKLNDAEKTYQEDLTVFQQRLQEAREESLESAEISSSCMFPEETSGRERKEPPDPLDLQLEQPKAQGSLIEDYQEKLSNAEEKIELMKQEFQKKEAEWELSREDLKRDAEEKLASMFLELREKAESEKLSIINRFELRESSMRHLQDQQAAQISDLERSLREQQGHLRQLEQELTRDEVLLCSQCGKEPSVAQDEKSAILLREKEDCALQLLTAQNRFLEERKEIMEKFAKEQDAFLLDTQEKHSHELQLLQQGHQQQLLALRMELETKHHSELTEQLASLESKQQALLETHVAKMQVKHDAEISALEKRHLSNLDELESCYVADIQTIRDEHKKALELLRAELEEQLQKKDSCHREILTQELEKLKLKHAEELQSVRNSLRVKMSAQHTESGKGPAADLQGAHQKAPAMALHNEGHQLEEDGDAALGGADTEDLQHHAEPREREGPHTVEMQTSQTELAKPQELQASQDQGAQVRDQVFLLSRELEECRGELEQLQQRRERENQEGATLICMLRADVDLAQSEGKALRDALRRLLDLFGETLKAAVTLKSRISERAGLLLDHEDAVDTSGAQLAAAALGEMWPDEGLLDIDRTLPEGAETSSVCEISSHVCESFFMSPENTQECEQPIRKVYQSLSTAVEGLLDMALDSSKQLEDARQLHRCVEKEFRHRDEEMAQAVQKQQELLERLREESAAKDRLALELHTAEGLLEGFKVEKADLQEALGKKEESEQQLIVELEDLRKQLQQASRELLTLKEENSVLWNQKETFTNEAKEREAALQKEVESLTRDQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVTTLKQQLATLDKHLRSQRQFMDEQAAEREHEREEFQQEIKWLEGQLRQATRPRPPGPRDSQCAKLDEEVELLQEKLREKLDGFNELVIKKDLADQQLLIQEEEIKHLEETNENIQRQMAQLQEELEKQRRSTEELEVVNSRNSEIEELKAIIEHLQENQEQLQKAKAEEIEQLHEVIEKLQSELSLMGPTVHEMSDLPPGSLHTELSCLQAEGMGGQALHNELQAAQAAKGAFGQLLADHGHSQALEALQERLQDAEAAAARHLTELEHCVALRQAEVEAMASRIQEFEATLKAKEAIIVQRDLEIDAVNKWKVSHSVELEALLLALAHFQHAVEQQTSATPDEPPKLQQLLVQCARLSHQLHVLYRRFLRCQVELGQHQPRVASVGCADPPAEAQGKRDGELEQDGVSSGLALAPHSLVAQAKEEQPEDCHLGNTSLRAQLRQLEEKLDPQAHSVAFRDTSMETCKLQQPNPLENGSSNHCHNGEESRPSPPNDVPAKTTWDVIGVIKNQDLLAQIEMPDSPTPEKLASQGGAFSSQASVHGASLLPEEAEPQKDPVRALDLSSWSSPEVLRKEPSLEPQHSLPLTPGVGTVSLHSVDISSPDWTDPLLQADVSGLLCYPGKSATGQAPLWVVAPSAEKHHVERTATEKDVEDFIVTSFDSQESLTSPSHELARRSDGSGKSDGPDIAAMLTLGSEGSETPTTDLVAATTGPFSRRFVQSPGAMREKEVHAKQMKALLQMVFDESHQILALSESQDSSSALSKGEPRDPLDGVPRDRQALSEGTSDRGEKEALGTHLTWSEELLQAIQEVFAREQENAELQPRPYSSDLGDYNSLVKKLEKVIQEQGDLQKVREHACLPDRSSLLAEIQALRAQLRMTHLQNQEKLQQLCAALTSTEARGSQREHQLRRQVELLAYKVEQEKCIANDLQKTLSKEQEAASDVRKRLMVEQGAVQDLKSELHACKQENTNLLESLDKVQQEVLRLRAVLDGKENELKVVLEELECERGKGQVLQAQQEEQQLRHLQREGQSSRALEELKISLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELRKSLEAERSRSLELSEALQHERLLTEQLSRNAQEACARQDTQAQHALLRKLKAEKARALELEAMLEKVQKQAAHTQQQLEAQAQERCLELRREKEVSGNLRSAVDALQTHKQELGCCLEREREKAAWLQAELEQLSARVKQQEARQDEKRMDRRSSREDLDKRKWQRVKEKLRELELQRQRDEHKIEQLQRLVRELRWKEEAPGGNGPCRGSPCLGSLERDQFQEQQQELEKIRQQLLCAAGFLTSFTNHTVDRTIKDWTSSNEKAVSSLMRTLEELKSELSMPTSFQKKMAAELQVQLMNELLSDNDALTKAVGMATREKAELCKTVSRLEKTLKHHTQKGCILNRQSKTPLKQDGMDLQSSLPHSDPEWHPQTTGGDTNTCNIKMEKLYLHYLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKVTASRPFTRFRTAVRVVIAVLRLRFLVKKWQEVDRKGALIHHSRSTRHGHRTSQRQNSPSGTRASLPTRDVSSGHTKDSRHSPKCSATSLGKGRSTSSTSSRLERSLTASQDPEQSLTEYIHLLEMTQQRLAGLPPDAPQKACPQKIKQ", "length": 2921 }, "evidence": [ { "id": "E1BKZ0", "url": "https://omabrowser.org/oma/group/E1BKZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58JQD6-1", "protein_name": "Pericentrin isoform X1", "gene_name": "pcnt", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDQDERQRKLEAGRAKLAHFRQRRAKSESSSTQKKTAKRKGQNVQTNDRSTEERHLEDTQTQDFHGEISEGYSIEASLNPDGTDSSAPEAHQCSRESDETDVQEQSSSSGSLAELPDQTEEQLTEMIMVAHTGKEQLKQLQAAVEKRNEIISQLSKNLQVALQSRDQVQVEAQQLTDQIQELQQQLQQAKEYLRSKTQGGVDVTQAAQNQLHVQLEESQQVTKEQECLLAQKEAEITELQQKLSVMKQSLSHLQHAFNHRGDDQTDFRLDRHSGLDLASVSAEFPCNSPDSISDALLQRLQTELDEERKNSQRAQEQVEAFQKRIRSLENEKTQMEARLAEVAEKQALDIEQYKAEKVELNQEMVRLDNLVKELQNHLREEEETGHHLRTKYEADISNYDLRLQTLEEERELNVAQLTEAHEAALRHLQEEHSKEINRIKELLSQAQSQYSDSPHNHSKDFGGEELWNKVYKQKLNEEPAAVGVVRNNYSFDVSGGGFQDVLMERYLASEGLQESSLIELSLEEHGLVENSETSRFELDSEVMIQVSNVPNNVSSDGEKSEPEQSVISVGEVHQHDEMSFTDTQWQNSTSVIDEINESAGNMDLAKELLIQQCQDLTEQLEERERQLEVLQEEVRRSAEEVEEARERWSKASEELEEAKWELELEREKRIQFEEVINQKTHEQDNLKNTQSHIETQDNERVMPEKTDSNKTSIPSSTELLLQELQEEKAQLVLQLKDQEQLLKDIYEKKDSDHSSSELSSLQVQRDELLIQLEQLKEKNQATSVLLGQRTLQVDQTNNELLQLKAEVEEKVAKLQDLEKEKTDLESKLTCLKENLTSMEEEKASLKMRLQALEDQVKSMENVLETELKNFEHQLESKDAELKEIRDSQEKAELEYMEKESALMKELAIVKQDVVEKQKQHEEEQKMLEEKHKKEVKYLNVRFERELSEQSAHLEDEQKRQISLIKQVYEREHERELTQLAAQHSEEINRLKEEFSRDLQEGMEAAHQAELQHTQTKHNLELEALRLSLTNLHTAQLELSQSNMQKDKDVALSELQTMLREKWAQESAMLQTRQQFELERIREQNREQEERNQRVHQQEIGNLNQKWETRLVEMKTSVEQLQSCKLEDLKAEYLLESEKIKTEFQSELNNVRHKLSETETALTQAEAALSDTQGKLEELQRSSDHDLKNLEKELKQALMDRDAAARAVEELVACHKVALQEQQERTRVLGQREIELKQEVDRLQSEKEELKTSSEQEISNLWSQLESMRTSRQELGELKEQLLARSSRVDDIERLKQEFTQQRQEIKEQNEVELENLRTYFEQRLRVTEESHREEIALLQLRLVEGALEDSVLKTGDASFLSEGNCEDDNSDAMAEITRQLEKHKEELDSLRLQLEERHQQELEQLRSSMTLAYKEDLLQARTELTDRYYKDIDQLNTKHAHELEQLRAKLSDNHIKEINKIRLQSAQEAARQAEAEVNERTKDYQARVTQLESRLSQLSKMHSEELEKAASQHREQLRQMEETHQKDVAEKLETQKAERNRASEEFTEKQDRLREQAKNQLASQREELQKSALEERGKLEQAFLEVQKQLDMESEKLGALQKSLECQESPQVVALKQKLQAQYDGEMSAAKSAMAAEVKELNALLQDQLKSKLQEALYRHQEEQKQLEDNLSLQRDAALDQQREQHAIELQTQKTLLEQRAAQLEHLEKECQELKIHHREELESLIANHKTALETLEMELTNKHKVELDKLEAVLQETNLAQLEAQEAELQARHKREKEELEERLLANMDTLESTYLKEIQLVQDEKRGELRDLQEHYSNEIERVRKEEQVIRDELRSELAKVHMEKFSAMAAELNQAHQAELSEAVASQRAALEDEHRSALEALQQQVVALEDQHSAALLEIADLANAEKLQLQKRLDELADQHQQQLQEFRGVSVRELEALRRELEEEASRQRLHFLEEAELLKCNAEEQLQQTITQLKEESDQEKAVALEELEKTLRQQHEQTELTYSDKMSQLTAQLQQLDTVVSQLRAEVSGLQGELEGKGAEMETLESLLHRREREKQEGDNLMAMLRTDLSTATQQRQDLQTARDKLQRIVKEMLRITITTEEHISHKLGSCVSGGQSEEKTPSSMTARNSRDSHETGEATGVEAETDCSVWSSAVDEVSELSQRLCESVFSGPEGELEAEGEELMLGACTRLRTSVDKLLELLSESSQQLEQMCSLQAVLNERFRDGGEAGASLLFQNSQLLEQLDHEASLKSQLQLELHKAEGLIEGYVAEKATLEEVLQQKETQEQRLAEELESARMQLKQIGENHTLLLRQREALTADLGDTEKGFLDAEEETALLAEAERLGQECVEVQRQAEKDRGGLASRLHMLEQALEEQESRAHQLEEQHRLQTEDLQQHIDALEKQLKHNRQFIDEQAVEREHERDEFQQEIKNLEAQLKHPSKGHASVDSKGQRIEDLAIQVESLQALIKDKMEDYSVLLLAKEQCQRDVEERNDEIEKLATRIRELEQALLSCAEASRTVTQLEQELQKGHKNFQELTQDNEALQQQLYANKLQISALQSKLDETRHRFPDVTPDPNLLEQLETTQQDLLAKEQEVELLSERASELEKDLVVREEEVRQLTLQLELTTRDSRAAEEQLHAHITHLQETVDTLTRRLEEGSDESILQLPSALLEEKNLEIDHLNQQLLQLQQELDTTNDNKILEEKQAEIEELRSLVERLQCDQERLQQAKEEEMEQLHEVINKLQEEISQLDPNHHEISDPNTDSPESSDFPWSPRPRQQRASEESLCQELNSHRLQSSRARLQELQTELEQATGEKDSLQRLLHSQEEQYGGQVEALGRSLGEERGKVAVLEQEVKKLTLQLEEKRTEAERLAACVEELEDQERSLQSCLRESELHLRMVEERRDEFQEEVKKQRAEKELLENQISELQHREQENQGELEDLRSRLEELEEHVQADMVNLSALETSKCELSMERNALRKREGRLQEEIERLRQEMTSKTNYIKELHEQQEAAVAKQGEAQKEVLTCAEETLAKAETALREREQQLILLRAEHEALRAELAAVKEGLSNSTERAEKLQEEGQTKDRALADLEIHNQHLKAELRSLQDDLAVQEEELAYQQRELEQLRQRCNLQDHHPKHSYRFLEGLSQDPSLSASLSSPEVLRRLDCSEERPSRLQVSHLSELSALHNASLELHSKPSPMERDKERAHVRQTFSPASEEAPPSTHSASPCSVTVSEHLSVLESLDADKVDDLDNSDVTPSRSPIGSTSPVSVPEWVSDGYGSNVSSELEAMLKLELENTERLDAHFVEYLRCRGMSPAENTDSAAGSMHDSHEALTPELQAMLKRVYQESCRILSLSHRPAPSGQSRPDSDPAPPPSWQRERRALQETILSLRELLCRMADREPKADDGDVDWRRELLQAVRSVFDSEREWLHTQLQAFMATSTQMDLTPLLDQLKKLFQKQEEQQWKSLEQIFNADRHSLLAEVRSLHAQLHASTQQSQQQLRQLQDSLHTTKEQGMETQHQLHSDVKELEMRLQQEQTQSHDLRCSLEAEKSRGLEQQKQLEAELKAVSVLKAELEEMRTELQSSYKHQEELKSEIHKLRLSLENFEAERQTCLQAVEKEQAKVQLLQEELKQQQLHSQQTTVQNKQTQESLHQALNEQASQVSQLNSALDQERITSSNLRSELQIEQSRCEALLAQERERTELALSRLEEERSRSTELSNSLSRQAQEHARRLEEEARRQESASAHDRKFIQDLRAQLEHERSQGEDLAAMLERLQGQVLEGKRRQAEAAEQEAHKEQEEIRRLRAALEGLQNQKTEVGRTLEAERGRAAQLQVELDAMKEKMRAVRVKEEQMERQRKQEQAEKERRQEHANEKLLELELLHQKDQQRLKQLQQTLTDLEREEKRLTSERLQRETHSNALNKHTNISQDSSTPSLIERLMKENSEFSECLAALSEEKISLKHTISCLERDLQSLKRMEQVKSSAVTEECMVSEKLAWQKEKATLQSALRKAEAELSKATASNENRPINDLSNSKVQRLYERYLRAESYRKSLVYQKRYLLLLLGRFQECEQATLALIARMGALPTLSQSRTSRPLNRFRTAVRVVIAISRLKFLNRKWQRATRKISAGTATVTVHGTGSSAAPALRTEVLRPQQGGVAFNSPPTRDHAFTQRGVVSSVVPPIKSPFRLNHRMYTSPVLGAAERSFSSTQDQERSLTEYIQHLETVQQRLGAACPVPRANRRHSLPDTMSFQQKWFLENRTWLYLSCLPPGSVWPLGSPSVLPNARKSAR", "length": 4302 }, "evidence": [ { "id": "E1BKZ0", "url": "https://omabrowser.org/oma/group/E1BKZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O95613-1", "protein_name": "Pericentrin", "gene_name": "PCNT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDSSHSEKKTAKRKGSAVDASVQEESPVTKEDSALCGGGDICKSTSCDDTPDGAGGAFAAQPEDCDGEKREDLEQLQQKQVNDHPPEQCGMFTVSDHPPEQHGMFTVGDHPPEQRGMFTVSDHPPEQHGMFTVSDHPPEQRGMFTISDHQPEQRGMFTVSDHTPEQRGIFTISDHPAEQRGMFTKECEQECELAITDLESGREDEAGLHQSQAVHGLELEALRLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQHAREKEEVVLRCGQEAAELKEKLQSEMEKNAQIVKTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQRAELEKIFQDKNQAERALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLELENLQASYEDLKAQSQEEIRRLWSQLDSARTSRQELSELHEQLLARTSRVEDLEQLKQREKTQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQRLQGAREDALLDSVEVGLSCVGLEEKPEKGRKDHVDELEPERHKESLPRFQAELEESHRHQLEALESPLCIQHEGHVSDRCCVETSALGHEWRLEPSEGHSQELPWVHLQGVQDGDLEADTERAARVLGLETEHKVQLSLLQTELKEEIELLKIENRNLYGKLQHETRLKDDLEKVKHNLIEDHQKELNNAKQKTELMKQEFQRKETDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIINKFELREAEMRQLQDQQAAQILDLERSLTEQQGRLQQLEQDLTSDDALHCSQCGREPPTAQDGELAALHVKEDCALQLMLARSRFLEERKEITEKFSAEQDAFLQEAQEQHARELQLLQERHQQQLLSVTAELEARHQAALGELTASLESKQGALLAARVAELQTKHAADLGALETRHLSSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLWKKDSLHQTILTQELEKLKRKHEGELQSVRDHLRTEVSTELAGTVAHELQGVHQGEFGSEKKTALHEKEETLRLQSAQAQPFHQEEKESLSLQLQKKNHQVQQLKDQVLSLSHEIEECRSELEVLQQRRERENREGANLLSMLKADVNLSHSERGALQDALRRLLGLFGETLRAAVTLRSRIGERVGLCLDDAGAGLALSTAPALEETWSDVALPELDRTLSECAEMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLMEMALDSSRQLEEARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVETADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATATDAEAREAALRKEVEDLTKEQSETRKQAEKDRSALLSQMKILESELEEQLSQHRGCAKQAEAVTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEGQLRQAAKPQPWGPRDSQQAPLDGEVELLQQKLREKLDEFNELAIQKESADRQVLMQEEEIKRLEEMNINIRKKVAQLQEEVEKQKNIVKGLEQDKEVLKKQQMSSLLLASTLQSTLDAGRCPEPPSGSPPEGPEIQLEVTQRALLRRESEVLDLKEQLEKMKGDLESKNEEILHLNLKLDMQNSQTAVSLRELEEENTSLKVIYTRSSEIEELKATIENLQENQKRLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSELLCSQAGGPRGQALQGELEAALEAKEALSRLLADQERRHSQALEALQQRLQGAEEAAELQLAELERNVALREAEVEDMASRIQEFEAALKAKEATIAERNLEIDALNQRKAAHSAELEAVLLALARIRRALEQQPLAAGAAPPELQWLRAQCARLSRQLQVLHQRFLRCQVELDRRQARRATAHTRVPGAHPQPRMDGGAKAQVTGDVEASHDAALEPVVPDPQGDLQPVLVTLKDAPLCKQEGVMSVLTVCQRQLQSELLLVKNEMRLSLEDGGKGKEKVLEDCQLPKVDLVAQVKQLQEKLNRLLYSMTFQNVDAADTKSLWPMASAHLLESSWSDDSCDGEEPDISPHIDTCDANTATGGVTDVIKNQAIDACDANTTPGGVTDVIKNWDSLIPDEMPDSPIQEKSECQDMSLSSPTSVLGGSRHQSHTAEAGPRKSPVGMLDLSSWSSPEVLRKDWTLEPWPSLPVTPHSGALSLCSADTSLGDRADTSLPQTQGPGLLCSPGVSAAALALQWAESPPADDHHVQRTAVEKDVEDFITTSFDSQETLSSPPPGLEGKADRSEKSDGSGFGARLSPGSGGPEAQTAGPVTPASISGRFQPLPEAMKEKEVRPKHVKALLQMVRDESHQILALSEGLAPPSGEPHPPRKEDEIQDISLHGGKTQEVPTACPDWRGDLLQVVQEAFEKEQEMQGVELQPRLSGSDLGGHSSLLERLEKIIREQGDLQEKSLEHLRLPDRSSLLSEIQALRAQLRMTHLQNQEKLQHLRTALTSAEARGSQQEHQLRRQVELLAYKVEQEKCIAGDLQKTLSEEQEKANSVQKLLAAEQTVVRDLKSDLCESRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQRAQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKEEKSRVVDLQAMLEKVQQQALHSQQQLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKAARRSAEARQSPAAAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQQTVRDLESKDEVPGSRLHLGSARRAAGSDADHLREQQRELEAMRQRLLSAARLLTSFTSQAVDRTVNDWTSSNEKAVMSLLHTLEELKSDLSRPTSSQKKMAAELQFQFVDVLLKDNVSLTKALSTVTQEKLELSRAVSKLEKLLKHHLQKGCSPSRSERSAWKPDETAPQSSLRRPDPGRLPPAASEEAHTSNVKMEKLYLHYLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERKITSRPFTRFRTAVRVVIAILRLRFLVKKWQEVDRKGALAQGKAPRPGPRARQPQSPPRTRESPPTRDVPSGHTRDPARGRRLAAAASPHSGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGVLPDSTSKKSCHPMIKQ", "length": 3336 }, "evidence": [ { "id": "E1BKZ0", "url": "https://omabrowser.org/oma/group/E1BKZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P48725-1", "protein_name": "Pericentrin", "gene_name": "Pcnt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 2898 }, "evidence": [ { "id": "E1BKZ0", "url": "https://omabrowser.org/oma/group/E1BKZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "E1BKZ0", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BKZ0", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BKZ0", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1BKZ0", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "E1BKZ0", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BKZ0", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "E1BKZ0", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "E1BKZ0", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" } ], "pmid": "" }, { "name": "positive regulation of intracellular protein transport", "id": "GO:0090316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090316", "evidence": [ { "database": "UniProtKB", "id": "E1BKZ0", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1433, "end_pos": 1435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1550, "end_pos": 1552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1602, "end_pos": 1604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2841, "end_pos": 2843, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2898, "end_pos": 2900, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKZ0" }, { "id": "PF10495", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10495" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pericentrin/AKAP-450 centrosomal targeting", "eco_id": "ECO_0000259", "start_pos": 2979, "end_pos": 3058, "start_aa": "Arg", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 2244, 2323 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1433, "end_pos": 1435 }, { "start_pos": 1550, "end_pos": 1552 }, { "start_pos": 1602, "end_pos": 1604 }, { "start_pos": 2841, "end_pos": 2843 }, { "start_pos": 2898, "end_pos": 2900 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJ93-1", "uniprot_ac": "E1BJ93", "uniprot_id": "E1BJ93_BOVIN", "mass": { "chemical_mass": 45762.0, "monoisotopic_mass": 45762.0 }, "refseq": { "ac": "XP_005207710", "name": "lymphoid enhancer-binding factor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207710" }, "gene_names": [ { "name": "LEF1", "type": "recommended", "evidence": [ { "id": "E1BJ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ93" } ] }, { "name": "LEF1", "type": "synonym", "evidence": [ { "id": "XP_005207710", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207710" } ] } ], "protein_names": [ { "name": "Lymphoid enhancer-binding factor 1", "type": "recommended", "evidence": [ { "id": "E1BJ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ93/entry#names_and_taxonomy" } ] }, { "name": "lymphoid enhancer-binding factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005207710", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207710" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], 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"https://www.reactome.org/PathwayBrowser/#R-BTA-8951430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9825892", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9825892", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005207710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207710", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MZ99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZ99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MZ99-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZ99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SB85", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SB85-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ93", "url": "https://www.uniprot.org/uniprotkb/E1BJ93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ93-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQLSGAGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQESYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPEIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESTSGGKRSSFPTCKAKAATPGPLLEMEAC", "length": 414, "header": "tr|E1BJ93-1|E1BJ93_BOVIN Isoform 1 of Lymphoid enhancer-binding factor 1 OS=Bos taurus OX=9913 GN=LEF1 PE=3 SV=3 CANONICAL=E1BJ93-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MAH2-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ93/entry#A0A3Q1MAH2-1", "sequence": { "sequence": "MPQLSGAGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQESYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPEIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESTSGGKRSSFPTCKAKAATPGPLLEMEAC", "length": 386, "header": "tr|A0A3Q1MAH2-1|E1BJ93_BOVIN Computationally mapped isoform of Lymphoid enhancer-binding factor 1 OS=Bos taurus OX=9913 GN=LEF1 PE=3 SV=1 CANONICAL=E1BJ93-1" }, "locus": { "chromosome": "6", "start_pos": 17199577, "end_pos": 17084564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067746.3", "url": 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[ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068676.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068676.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061494.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061494.2" } ] } }, { "isoform_ac": "A0AAA9SB85-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ93/entry#A0AAA9SB85-1", "sequence": { "sequence": "MAGVARQAQTSQESYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPEIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI", "length": 303, "header": "tr|A0AAA9SB85-1|E1BJ93_BOVIN Computationally mapped isoform of Lymphoid enhancer-binding factor 1 OS=Bos taurus OX=9913 GN=LEF1 PE=3 SV=1 CANONICAL=E1BJ93-1" }, "locus": { "chromosome": "6", "start_pos": 17187323, "end_pos": 17085985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107434.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107434.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079451.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079451.1" } ] } }, { "isoform_ac": "E1BJ93-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ93/entry#E1BJ93-1", "sequence": { "sequence": "MPQLSGAGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQESYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPEIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESTSGGKRSSFPTCKAKAATPGPLLEMEAC", "length": 414, "header": "tr|E1BJ93-1|E1BJ93_BOVIN Isoform 1 of Lymphoid enhancer-binding factor 1 OS=Bos taurus OX=9913 GN=LEF1 PE=3 SV=3 CANONICAL=E1BJ93-1" }, "locus": { "chromosome": "6", "start_pos": 17199577, "end_pos": 17084564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008991.8", "url": "https://www.ensembl.org/id/ENSBTAT00000008991.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008991.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008991.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 208, "start_aa": "Thr", "end_pos": 208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr208", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 404, "start_aa": "Thr", "end_pos": 404, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr404", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:535399", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535399", "resource": "KEGG Pathway" }, { "id": "R-BTA-201722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-201722", "resource": "Reactome", "description": "Formation of the beta-catenin:TCF transactivating complex" }, { "id": "R-BTA-3769402", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3769402", "resource": "Reactome", "description": "Deactivation of the beta-catenin transactivating complex" }, { "id": "R-BTA-4086398", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4086398", "resource": "Reactome", "description": "Ca2+ pathway" }, { "id": "R-BTA-4641265", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4641265", "resource": "Reactome", "description": "Repression of WNT target genes" }, { "id": "R-BTA-8951430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951430", "resource": "Reactome", "description": "RUNX3 regulates WNT signaling" }, { "id": "R-BTA-9825892", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9825892", "resource": "Reactome", "description": "Regulation of MITF-M-dependent genes involved in cell cycle and proliferation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XV79-1", "protein_name": "Lymphoid enhancer-binding factor 1", "gene_name": "LEF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPQLPGAGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESEIAPGSGGHEVSRQTPAQDSYHDKGREHPEEGKHPDGGLYSKGPSYSGYSGYIMMPNMNNDPYMPNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVSSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPISSGFRQPYPSSLSVDPSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHNDSELMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI", "length": 397 }, "evidence": [ { "id": "E1BJ93", "url": "https://omabrowser.org/oma/group/E1BJ93/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P27782-1", "protein_name": "Lymphoid enhancer-binding factor 1", "gene_name": "Lef1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPQLSGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESEIIPASNGHEVVRQAPSSQEPYHDKAREHPDEGKHPDGGLYNKGPSYSSYSGYIMMPNMNSDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPEIPTFYPLSPGGVGQITPPIGWQGQPVYPITGGFRQPYPSSLSGDTSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI", "length": 397 }, "evidence": [ { "id": "E1BJ93", "url": "https://omabrowser.org/oma/group/E1BJ93/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QXN1-1", "protein_name": "Lymphoid enhancer-binding factor 1", "gene_name": "Lef1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQLSGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESEIIPASNGHEVVGQTQSSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNSDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSEVNPKQGMSRHPPAPEMPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQAYPSSLSGDTSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPEHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI", "length": 397 }, "evidence": [ { "id": "E1BJ93", "url": "https://omabrowser.org/oma/group/E1BJ93/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UJU2-1", "protein_name": "Lymphoid enhancer-binding factor 1", "gene_name": "LEF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI", "length": 399 }, "evidence": [ { "id": "E1BJ93", "url": "https://omabrowser.org/oma/group/E1BJ93/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 15, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BJ93", "url": "https://www.uniprot.org/uniprotkb/E1BJ93" } ], "pmid": "" }, { "name": "DNA binding, bending", "id": "GO:0008301", "url": 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"database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "519751", "url": "https://www.ncbi.nlm.nih.gov/gene/519751", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519751", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519751", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMNSVET", "url": "https://omabrowser.org/oma/group/AMNSVET/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MCV7", "url": "https://www.orthodb.org/?gene=A0A3Q1MCV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BJ04", "url": "https://www.orthodb.org/?gene=E1BJ04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23159:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23159:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192793", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192793", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCL9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXQ9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7W1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7W1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZI5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ04", "url": "https://www.uniprot.org/uniprotkb/E1BJ04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ04-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKASRSVGSAPKVSGTSRVQAADKARPESSSSASAGSRPVKPGAAAALSKTKSSDDLLAGMAGGVTVTNGVKGKKNACSSAAPAAPAPAVSATENRPRTGTGTSSSTKRSTCTGNKEPSSTRERLRERTRLNQSKKLPSAGQGANDVASAKRSRSRTAAECDVRMSKSKSDNQISDKAALEARVKDLLTLAKTKDVEILHLRSELRDMRAQLGISEDPLTEGAETSEEKEASTVHQPTDVESTLLQLQEQNAAIREELNQLKNENRMLKDRLNALGFSLEQRLDHSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSLDNLDSECSEVYQPLTSSDDALDAPSSSESEGLPSVERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENSRFEREQLLGVQQHLSNTLKMAEQDNKEAQELIGALKERSHHMERAVESEQKGKAALAATLEELRATLASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQGEAKKQIEDLNVAVEKLRSELEERDTERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPSPAAAAMPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSSTSRPASLPRVPAMESAKTLSVSRRSSEEMKRDVSAPEGTSPAALMAMGATSPQLSLSSSPTASVTPTARSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFTLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET", "length": 1119, "header": "tr|E1BJ04-1|E1BJ04_BOVIN Isoform 1 of Cytospin-A OS=Bos taurus OX=9913 GN=SPECC1L PE=3 SV=1 CANONICAL=E1BJ04-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MCL9-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ04/entry#A0A3Q1MCL9-1", "sequence": { "sequence": "MASLTRWTFACKCIAKRQPRMKKASRSVGSAPKVSGTSRVQAADKARPESSSSASAGSRPVKPGAAAALSKTKSSDDLLAGMAGGVTVTNGVKGKKNACSSAAPAAPAPAVSATENRPRTGTGTSSSTKRSTCTGNKEPSSTRERLRERTRLNQSKKLPSAGQGANDVASAKRSRSRTAAECDVRMSKSKSDNQISDKAALEARVKDLLTLAKTKDVEILHLRSELRDMRAQLGISEDPLTEGAETSEEKEASTVHQPTDVESTLLQLQEQNAAIREELNQLKNENRMLKDRLNALGFSLEQRLDHSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSLDNLDSECSEVYQPLTSSDDALDAPSSSESEGLPSVERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENSRFEREQLLGVQQHLSNTLKMAEQDNKEAQELIGALKERSHHMERAVESEQKGKAALAATLEELRATLASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQGEAKKQIEDLNVAVEKLRSELEERDTERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPSPAAAAMPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSSTSRPASLPRVPAMESAKTLSVSRRSSEEMKRDVSAPEGTSPAALMAMGATSPQLSLSSSPTASVTPTARSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFTLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET", "length": 1139, "header": "tr|A0A3Q1MCL9-1|E1BJ04_BOVIN Computationally mapped isoform of Cytospin-A OS=Bos taurus OX=9913 GN=SPECC1L PE=3 SV=1 CANONICAL=E1BJ04-1" }, "locus": { "chromosome": "17", "start_pos": 71692420, "end_pos": 71613410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085585.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085585.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068592.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068592.2" } ] } }, { "isoform_ac": "A0A3Q1MCV7-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ04/entry#A0A3Q1MCV7-1", "sequence": { "sequence": "MKKASRSVGSAPKVSGTSRVQAADKARPESSSSASAGSRPVKPGAAAALSKTKSSDDLLAGMAGGVTVTNGVKGKKNACSSAAPAAPAPAVSATENRPRTGTGTSSSTKRSTCTGQGANDVASAKRSRSRTAAECDVRMSKSKSDNQISDKAALEARVKDLLTLAKTKDVEILHLRSELRDMRAQLGISEDPLTEGAETSEEKEASTVHQPTDVESTLLQLQEQNAAIREELNQLKNENRMLKDRLNALGFSLEQRLDHSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSLDNLDSECSEVYQPLTSSDDALDAPSSSESEGLPSVERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENSRFEREQLLGVQQHLSNTLKMAEQDNKEAQELIGALKERSHHMERAVESEQKGKAALAATLEELRATLASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQGEAKKQIEDLNVAVEKLRSELEERDTERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPSPAAAAMPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSSTSRPASLPRVPAMESAKTLSVSRRSSEEMKRDVSAPEGTSPAALMAMGATSPQLSLSSSPTASVTPTARSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFTLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET", "length": 1092, "header": "tr|A0A3Q1MCV7-1|E1BJ04_BOVIN Computationally mapped isoform of Cytospin-A OS=Bos taurus OX=9913 GN=SPECC1L PE=3 SV=1 CANONICAL=E1BJ04-1" }, "locus": { "chromosome": "17", "start_pos": 71675123, "end_pos": 71613410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076366.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076366.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066641.1", "url": "https://www.ensembl.org/id/ENSBTAP00000066641.1" } ] } }, { "isoform_ac": "A0AAA9RXQ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ04/entry#A0AAA9RXQ9-1", "sequence": { "sequence": "MKKASRSVGSAPKVSGTSRVQAADKARPESSSSASAGSRPVKPGAAAALSKTKSSDDLLAGMAGGVTVTNGVKGKKNACSSAAPAAPAPAVSATENRPRTGTGTSSSTKRSTCTGNKEPSSTRERLRERTRLNQSKKLPSAGQGANDVASAKRSRSRTAAECDVRMSKSKSDNQISDKAALEARVKDLLTLAKTKDVEILHLRSELRDMRAQLGISEDPLTEGAETSEEKEASTVHQPTDVESTLLQLQEQNAAIREELNQLKNENRMLKDRLNALGFSLEQRLDHSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSLDNLDSECSEVYQPLTSSDDALDAPSSSESEGLPSVERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENSRFEREQLLGVQQHLSNTLKMAEQDNKEAQELIGALKERSHHMERAVESEQKGKAALAATLEELRATLASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQGEAKKQIEDLNVAVEKLRSELEERDTERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPSPAAAAMPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSSTSRPASLPRVPAMESAKTLSVSRRSSEEMKRDVSAPEGTSPAALMAMGATSPQLSLSSSPTASVTPTARSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQRRNFTLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET", "length": 1080, "header": "tr|A0AAA9RXQ9-1|E1BJ04_BOVIN Computationally mapped isoform of Cytospin-A OS=Bos taurus OX=9913 GN=SPECC1L PE=3 SV=1 CANONICAL=E1BJ04-1" }, "locus": { "chromosome": "17", "start_pos": 71675123, "end_pos": 71613410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090819.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090819.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074607.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074607.1" } ] } }, { "isoform_ac": "A0AAA9S7W1-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ04/entry#A0AAA9S7W1-1", "sequence": { "sequence": "MKKASRSVGSAPKVSGTSRVQAADKARPESSSSASAGSRPVKPGAAAALSKTKSSDDLLAGMAGGVTVTNGVKGKKNACSSAAPAAPAPAVSATENRPRTGTGTSSSTKRSTCTGQGANDVASAKRSRSRTAAECDVRMSKSKSDNQISDKAALEARVKDLLTLAKTKDVEILHLRSELRDMRAQLGISEDPLTEGAETSEEKEASTVHQPTDVESTLLQLQEQNAAIREELNQLKNENRMLKDRLNALGFSLEQRLDHSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSLDNLDSECSEVYQPLTSSDDALDAPSSSESEGLPSVERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENSRFEREQLLGVQQHLSNTLKMAEQDNKEAQELIGALKERSHHMERAVESEQKGKAALAATLEELRATLASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQGEAKKQIEDLNVAVEKLRSELEERDTERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQEHLLRTSSTSRPASLPRVPAMESAKTLSVSRRSSEEMKRDVSAPEGTSPAALMAMGATSPQLSLSSSPTASVTPTARSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFTLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET", "length": 1031, "header": "tr|A0AAA9S7W1-1|E1BJ04_BOVIN Computationally mapped isoform of Cytospin-A OS=Bos taurus OX=9913 GN=SPECC1L PE=3 SV=1 CANONICAL=E1BJ04-1" }, "locus": { "chromosome": "17", "start_pos": 71675123, "end_pos": 71613410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130297.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130297.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082122.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082122.1" } ] } }, { "isoform_ac": "A0AAA9SZI5-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ04/entry#A0AAA9SZI5-1", "sequence": { "sequence": "MKKASRSVGSAPKVSGTSRVQAADKARPESSSSASAGSRPVKPGAAAALSKTKSSDDLLAGMAGGVTVTNGVKGKKNACSSAAPAAPAPAVSATENRPRTGTGTSSSTKRSTCTGNKEPSSTRERLRERTRLNQSKKLPSAGQGANDVASAKRSRSRTAAECDVRMSKSKSDNQISDKAALEARVKDLLTLAKTKDVEILHLRSELRDMRAQLGISEDPLTEGAETSEEKEASTVHQPTDVESTLLQLQEQNAAIREELNQLKNENRMLKDRLNALGFSLEQRLDHSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSLDNLDSECSEVYQPLTSSDDALDAPSSSESEGLPSVERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENSRFEREQLLGVQQHLSNTLKMAEQDNKEAQELIGALKERSHHMERAVESEQKGKAALAATLEELRATLASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQGEAKKQIEDLNVAVEKLRSELEERDTERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPSPAAAAMPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSSTSRPASLPRVPAMESAKTLSVSRRSSEEMKRDVSAPEGTSPAALMAMGATSPQLSLSSSPTASVTPTARSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQSPACQS", "length": 1037, "header": "tr|A0AAA9SZI5-1|E1BJ04_BOVIN Computationally mapped isoform of Cytospin-A OS=Bos taurus OX=9913 GN=SPECC1L PE=3 SV=1 CANONICAL=E1BJ04-1" }, "locus": { "chromosome": "17", "start_pos": 71675123, "end_pos": 71630918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103473.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103473.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089709.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089709.1" } ] } }, { "isoform_ac": "E1BJ04-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ04/entry#E1BJ04-1", "sequence": { "sequence": "MKKASRSVGSAPKVSGTSRVQAADKARPESSSSASAGSRPVKPGAAAALSKTKSSDDLLAGMAGGVTVTNGVKGKKNACSSAAPAAPAPAVSATENRPRTGTGTSSSTKRSTCTGNKEPSSTRERLRERTRLNQSKKLPSAGQGANDVASAKRSRSRTAAECDVRMSKSKSDNQISDKAALEARVKDLLTLAKTKDVEILHLRSELRDMRAQLGISEDPLTEGAETSEEKEASTVHQPTDVESTLLQLQEQNAAIREELNQLKNENRMLKDRLNALGFSLEQRLDHSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSLDNLDSECSEVYQPLTSSDDALDAPSSSESEGLPSVERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENSRFEREQLLGVQQHLSNTLKMAEQDNKEAQELIGALKERSHHMERAVESEQKGKAALAATLEELRATLASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQGEAKKQIEDLNVAVEKLRSELEERDTERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPSPAAAAMPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSSTSRPASLPRVPAMESAKTLSVSRRSSEEMKRDVSAPEGTSPAALMAMGATSPQLSLSSSPTASVTPTARSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFTLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET", "length": 1119, "header": "tr|E1BJ04-1|E1BJ04_BOVIN Isoform 1 of Cytospin-A OS=Bos taurus OX=9913 GN=SPECC1L PE=3 SV=1 CANONICAL=E1BJ04-1" }, "locus": { "chromosome": "17", "start_pos": 71675123, "end_pos": 71613410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029400.4", "url": "https://www.ensembl.org/id/ENSBTAT00000029400.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029400.2", "url": "https://www.ensembl.org/id/ENSBTAP00000029400.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 840, "start_aa": "Thr", "end_pos": 840, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr840", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:519751", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519751", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q0KHX7-1", "protein_name": "Split discs, isoform B", "gene_name": "spdi", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIKLKSLFRRGQGNSSSHSSNSSHKQQQNSSNNNRQKSQSSTSLNTAHEQQQQHSITAATTKFYAHQETASYERGVDVGDEGALLLTNQQQEQRRQQQQLLQQPQSNTLPQKKSKLKGQKQPKLLPVQQPHSNAPEPHDPQQPLMTSLAAVPQASATGSSSNSNINNNNALAALQDGGAAAAAAADFYQQLAAAATATATATSANGSNTSADSPVSSFPAAAAAVAVAAVAASSYQQQQQQQQLLNNEQQQQQLLEANNKMQELHKQMERFRSEQMQLETRITELLPYQSEVAKLKGDLVKMQSLQEKSQMEIGNLKYENESLRNRLRDVVNSPLSDAEKHQIIQDSQRLHSSAPASIALPSTHDAHDGTPCLTPDWDKQSSSSEISVACLQDKIIQMEETHYSTNEELQATLQELADLQTQLTDTQTENERLAEEKDVLFQSLCRQTEKLNESRTQISTLQELLLRDTKQPAPEVSASEREQKLLDLIKTSQEEREAVLLKQEELGAELAEMKQAREAGQLELQRQRERIALLDSQLDAANAERRQGEAQFSQAMEEISQRAIEISRLSTLLENARSKIEELEADLSRGDKTDLSEVLDVARKEKDALEERVAELQDQCSRSQAELRRLRDQLSGLTEECKVVKNNAKCAVSHLEYRLEQLQRDKDKIAGEWQALEERVAELQVQCKCHQEDKAQLQSLLAETQRHLGDVQLKLGEAECRLDQETQLRRKEAEEWQQFQADLLMTVRVANDFKTEALSAREQLVLDNKTQKEKIRLLEQQLEKLTKQQMQQSETPQSVLSTVQREMEMATRRSKLSFSRQDSRLSVKTLIESIENNKAQGKADESESHYSSTSSLNSGTPDLGTTPIIFPPSSDWHESIRLPVLQSTNLHVNVGNEVGAGQGTNTSSGSGGDLASTTKATLPLRDQQQLAITSTQSQVQNVSQPSTPATPSSAGSSSSGGLPFGNVSKSFISGERKDPLNMLAKNGGSKRNALLKWCQNKTVGYRNIDITNFSSSWNDGLAFCAILHSYLPDRIPYDQLTPANKRRNFSLAFAAAESVGIGTTLNINDMCQIERPDWMQVMSYVTAVYKYFET", "length": 1094 }, "evidence": [ { "id": "E1BJ04", "url": "https://omabrowser.org/oma/group/E1BJ04/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2KN98-1", "protein_name": "Cytospin-A", "gene_name": "Specc1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKANRSAGSVPKVSGISKPQTVEKSKPENSSSAPTGVKPVRPGAAAALSKTKSNDDLLAGMAGGVNVTNGIKAKKSTCSSAAPSAPAPAMTISENKSKISTGTSSSAKRSTSAGNKESSSTRERLRERTRLNQSKKLPSVSQGANDVALAKRSRSRTAAEGDIRMSKSKSDNQISDKAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGISEDHCEGEDRSEVKETIIAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGVPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFGRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDTIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSELEEKDTERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNAAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRSNYGELPVQEHLLRTSSTSRPASLPRVPAMESAKTISVSRRSSEEMKRDISASEGASPASLMAMGTTSPQLSLSSSPTASVTPSTRSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKKRNFTLAFQAAESVGIKSTLDINEMARTERPDWQNVMLYVTAIYKYFET", "length": 1118 }, "evidence": [ { "id": "E1BJ04", "url": "https://omabrowser.org/oma/group/E1BJ04/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2KN99-1", "protein_name": "Cytospin-A", "gene_name": "Specc1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKANRSAGSVPKVSGISKPQTVEKSKSENSSSAPTGGKPVKPGAAAALSKTKSNDDLLAGMAGGVNVTNGVKAKKSNCSSAAPSAPAPAMTISESKSKSSTGTSSSAKRSTSAGNKESSSTRERLRERTRLNQSKKLPSVSQGANDVALAKRSRSRTATEGDIRMSKSKSDNQISDKAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGISEDHCEGEDRSEEKETIIAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMAHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGVPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFGRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLEKEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDTIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSELEEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDLERENKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNAAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPVSTSKPLTALSDKRSNYGEIPGQEHLLRTSSTSRPASLPRVPAMESAKTISVSRRSSEEMKRDISASEGASPASLMAMGTTSPQLSLSSSPTASVTPSTRSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQEKKRNFTLAFQAAESVGIKSTLDINEMARTERPDWQNVMLYVTAIYKYFET", "length": 1118 }, "evidence": [ { "id": "E1BJ04", "url": "https://omabrowser.org/oma/group/E1BJ04/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q69YQ0-1", "protein_name": "Cytospin-A", "gene_name": "SPECC1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKASRSVGSVPKVSAISKTQTAEKIKPENSSSASTGGKLVKPGTAASLSKTKSSDDLLAGMAGGVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTGTASSTKRSTSTGNKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEGASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET", "length": 1117 }, "evidence": [ { "id": "E1BJ04", "url": "https://omabrowser.org/oma/group/E1BJ04/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BJ04", "url": "https://www.uniprot.org/uniprotkb/E1BJ04" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "E1BJ04", "url": "https://www.uniprot.org/uniprotkb/E1BJ04" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "E1BJ04", "url": "https://www.uniprot.org/uniprotkb/E1BJ04" } ], "pmid": "" }, { "name": "filamentous actin", "id": "GO:0031941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031941", "evidence": [ { "database": "UniProtKB", "id": "E1BJ04", "url": "https://www.uniprot.org/uniprotkb/E1BJ04" } ], "pmid": "" }, { "name": "gap junction", "id": "GO:0005921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005921", "evidence": [ { "database": "UniProtKB", "id": "E1BJ04", "url": "https://www.uniprot.org/uniprotkb/E1BJ04" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E1BJ04", "url": "https://www.uniprot.org/uniprotkb/E1BJ04" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "E1BJ04", "url": "https://www.uniprot.org/uniprotkb/E1BJ04" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "E1BJ04", "url": "https://www.uniprot.org/uniprotkb/E1BJ04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1037, "end_pos": 1039, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1073, "end_pos": 1075, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 840 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1037, "end_pos": 1039 }, { "start_pos": 1073, "end_pos": 1075 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 389, "end_pos": 391 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG65-1", "uniprot_ac": "E1BG65", "uniprot_id": "E1BG65_BOVIN", "mass": { "chemical_mass": 102285.0, "monoisotopic_mass": 102285.0 }, "refseq": { "ac": "XP_010801384", "name": "semaphorin-6C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801384" }, "gene_names": [ { "name": "SEMA6C", "type": "recommended", "evidence": [ { "id": "E1BG65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ] }, { "name": "SEMA6C", "type": "synonym", "evidence": [ { "id": "XP_010801384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801384" } ] } ], "protein_names": [ { "name": "Semaphorin-6C", "type": "recommended", "evidence": [ { "id": "E1BG65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG65/entry#names_and_taxonomy" } ] }, { "name": "Semaphorin-Y", "type": "synonym", "evidence": [ { "id": "E1BG65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG65/entry#names_and_taxonomy" } ] }, { "name": "semaphorin-6C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010801384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801384" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SEMA6C", "url": "https://www.uniprot.org/uniprotkb/E1BG65", "locus": { "chromosome": "3", "start_pos": 19687263, "end_pos": 19673478, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007281", "url": "https://www.ensembl.org/id/ENSBTAG00000007281" } ] } } ], "crossref": [ { "id": "E1BG65", "url": "https://alphafold.ebi.ac.uk/entry/E1BG65", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007281", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007281", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "524464", "url": "https://www.ncbi.nlm.nih.gov/gene/524464", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524464", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524464", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMKNCAM", "url": "https://omabrowser.org/oma/group/DMKNCAM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BG65", "url": "https://www.orthodb.org/?gene=E1BG65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010801384", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801384", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHT4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MHZ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MHZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MLI0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MLI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJI5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJI5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG65-1", "url": "https://www.uniprot.org/uniprotkb/E1BG65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRAPHFMPLLLLLLLSIPHTQAAFPQDPLPLLTSDLHGISPLSWFRGLEDDAVVAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKYLTWRSQDVENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAVFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVHALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVNLYGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGVAALFPSSRDLPDDVLTFIKAHPLLDPAVPPATHQPLLTLTSRALLTQVAVDGMAGPYSNITVLFLGSNDGTVLKVLPPGGQSGGSEPILLEEIDAYSPSRCSGKRAAQTARRVIGLELDTEGHRLFVAFSGCIIYLPLSRCARHGACRRSCLASQDPYCGWDSSRGCVDIRAPGGIDVDPTGNQESMEHDDCQDGATGSQSGTGDSTYVLLSPGPSPETPSPPSDAHPRPQSSTLGAHTQGVRRDLPPASASRSVPIPLLLACVAAAFALGASVSGLLVSCACRRAHRRRSKDIESAGIPRPLSLRSLARLHGAGPEPPPPSKDGEGAQTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRHAGGPWEWNQNGNNAKEGRSRARGGNAAGGAAPRVLVKPPPPGCPGQAVEVTTLEELLRYLHGPQAPRKEAEPPVAAPFTSRPLPPEPSPTLFAGPSLLPRDCAPPRRLDVPPEGKCPAPAARPALSAPAPRLGVGGSRKLPFSSHRAPPALLTRVPSGGPSRYSGGAGRHLLYLGRPEGHRGRALKRVEGREAPGAPEASLCRALLAGGRP", "length": 956, "header": "tr|E1BG65-1|E1BG65_BOVIN Isoform 1 of Semaphorin-6C OS=Bos taurus OX=9913 GN=SEMA6C PE=3 SV=3 CANONICAL=E1BG65-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LHT4-1", "url": "https://www.uniprot.org/uniprotkb/E1BG65/entry#A0A3Q1LHT4-1", "sequence": { "sequence": "MPRAPHFMPLLLLLLLSIPHTQAAFPQDPLPLLTSDLHGISPLSWFRGLEDDAVVAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKYLTWRSQDVENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAVFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVHALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVNLYGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGVAALFPSSRDLPDDVLTFIKAHPLLDPAVPPATHQPLLTLTSRALLTQVAVDGMAGPYSNITVLFLGSNDGTVLKVLPPGGQSGGSEPILLEEIDAYSPSRCSGKRAAQTARRVIGLELDTEGHRLFVAFSGCIIYLPLSRCARHGACRRSCLASQDPYCGWDSSRGCVDIRAPGGIDVDPTGNQESMEHDDCQDGATGSQSGTGDSTYGVRRDLPPASASRSVPIPLLLACVAAAFALGASVSGLLVSCACRRAHRRRSKDIESAGIPRPLSLRSLARLHGAGPEPPPPSKDGEGAQTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRHAGGPWEWNQNGNNAKEGRSRARGGNAAGGAAPRVLVKPPPPGCPGQAVEVTTLEELLRYLHGPQAPRKEAEPPVAAPFTSRPLPPEPSPTLFAGPSLLPRDCAPPRRLDVPPEGKCPAPAARPALSAPAPRLGVGGSRKLPFSSHRAPPALLTRVPSGGPSRELLQGLKWDPRGPCPQRP", "length": 893, "header": "tr|A0A3Q1LHT4-1|E1BG65_BOVIN Computationally mapped isoform of Semaphorin-6C OS=Bos taurus OX=9913 GN=SEMA6C PE=3 SV=2 CANONICAL=E1BG65-1" }, "locus": { "chromosome": "3", "start_pos": 19686259, "end_pos": 19677608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082115.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082115.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058390.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058390.2" } ] } }, { "isoform_ac": "A0A3Q1MHZ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BG65/entry#A0A3Q1MHZ5-1", "sequence": { "sequence": "MPRAPHFMPLLLLLLLSIPHTQAAFPQDPLPLLTSDLHGISPLSWFRGLEDDAVVAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKYLTWRSQDVENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAVFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVHALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVNLYGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGVAALFPSSRDLPDDVLTFIKAHPLLDPAVPPATHQPLLTLTSRALLTQVAVDGMAGPYSNITVLFLGSNDGTVLKVLPPGGQSGGSEPILLEEIDAYSPSRSCLASQDPYCGWDSSRGCVDIRAPGGIDVDPTGNQESMEHDDCQDGATGSQSGTGDSTYGVRRDLPPASASRSVPIPLLLACVAAAFALGASVSGLLVSCACRRAHRRRSKDIESAGIPRPLSLRSLARLHGAGPEPPPPSKDGEGAQTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRHAGGPWEWNQNGNNAKEGRSRARGGNAAGGAAPRVLVKPPPPGCPGQAVEVTTLEELLRYLHGPQAPRKEAEPPVAAPFTSRPLPPEPSPTLFAGPSLLPRDCAPPRRLDVPPEGKCPAPAARPALSAPAPRLGVGGSRKLPFSSHRAPPALLTRVPSGGPSRYSGGAGRHLLYLGRPEGHRGRALKRVEGREAPGAPEASLCRALLAGGRP", "length": 875, "header": "tr|A0A3Q1MHZ5-1|E1BG65_BOVIN Computationally mapped isoform of Semaphorin-6C OS=Bos taurus OX=9913 GN=SEMA6C PE=3 SV=2 CANONICAL=E1BG65-1" }, "locus": { "chromosome": "3", "start_pos": 19686177, "end_pos": 19677608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084524.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084524.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070858.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070858.2" } ] } }, { "isoform_ac": "A0A3Q1MLI0-1", "url": "https://www.uniprot.org/uniprotkb/E1BG65/entry#A0A3Q1MLI0-1", "sequence": { "sequence": "MPRAPHFMPLLLLLLLSIPHTQAAFPQDPLPLLTSDLHGISPLSWFRGLEDDAVVAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKYLTWRSQDVENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAVFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVHALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVNLYGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGVAALFPSSRDLPDDVLTFIKAHPLLDPAVPPATHQPLLTLTSRALLTQVAVDGMAGPYSNITVLFLGSNDGTVLKVLPPGGQSGGSEPILLEEIDAYSPSRCSGKRAAQTARRVIGLELDTEGHRLFVAFSGCIIYLPLSRCARHGACRRSCLASQDPYCGWDSSRGCVDIRAPGGIDVDPTGNQESMEHDDCQDGATGSQSGTGDSTYGVRRDLPPASASRSVPIPLLLACVAAAFALGASVSGLLVSCACRRAHRRRSKDIESAGIPRPLSLRSLARLHGAGPEPPPPSKDGEGAQTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRHAGGPWEWNQNGNNAKEGRSRARGGNAAGGAAPRVLVKPPPPGCPGQAVEVTTLEELLRYLHGPQAPRKEAEPPVAAPFTSRPLPPEPSPTLFAGPSLLPRDCAPPRRLDVPPEGKCPAPAARPALSAPAPRLGVGGSRKLPFSSHRAPPALLTRVPSGGPSRYSGGAGRHLLYLGRPEGHRGRALKRVEGREAPGAPEASLCRALLAGGRP", "length": 924, "header": "tr|A0A3Q1MLI0-1|E1BG65_BOVIN Computationally mapped isoform of Semaphorin-6C OS=Bos taurus OX=9913 GN=SEMA6C PE=3 SV=1 CANONICAL=E1BG65-1" }, "locus": { "chromosome": "3", "start_pos": 19686177, "end_pos": 19677608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070067.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070067.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072555.1", "url": "https://www.ensembl.org/id/ENSBTAP00000072555.1" } ] } }, { "isoform_ac": "A0ABI0NJI5-1", "url": "https://www.uniprot.org/uniprotkb/E1BG65/entry#A0ABI0NJI5-1", "sequence": { "sequence": "MPRAPHFMPLLLLLLLSIPHTQAAFPQDPLPLLTSDLHGISPLSWFRGLEDDAVVAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKYLTWRSQDVENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAVFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVHALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVNLYGRSALFGVFTTQTNRPGSCAGVGVAALFPSSRDLPDDVLTFIKAHPLLDPAVPPATHQPLLTLTSRALLTQVAVDGMAGPYSNITVLFLGSNDGTVLKVLPPGGQSGGSEPILLEEIDAYSPSRCSGKRAAQTARRVIGLELDTEGHRLFVAFSGCIIYLPLSRCARHGACRRSCLASQDPYCGWDSSRGCVDIRAPGGIDVDPTGNQESMEHDDCQDGATGSQSGTGDSTYGVRRDLPPASASRSVPIPLLLACVAAAFALGASVSGLLVSCACRRAHRRRSKDIESAGIPRPLSLRSLARLHGAGPEPPPPSKDGEGAQTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRHAGGPWEWNQNGNNAKEGRSRARGGNAAGGAAPRVLVKPPPPGCPGQAVEVTTLEELLRYLHGPQAPRKEAEPPVAAPFTSRPLPPEPSPTLFAGPSLLPRDCAPPRRLDVPPEGKCPAPAARPALSAPAPRLGVGGSRKLPFSSHRAPPALLTRVPSGGPSRYSGGAGRHLLYLGRPEGHRGRALKRVEGREAPGAPEASLCRALLAGGRP", "length": 880, "header": "tr|A0ABI0NJI5-1|A0ABI0NJI5_BOVIN Computationally mapped isoform of Semaphorin 6C OS=Bos taurus OX=9913 GN=SEMA6C PE=4 SV=1 CANONICAL=E1BG65-1" }, "locus": { "chromosome": "3", "start_pos": 19686177, "end_pos": 19677608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149513.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149513.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104578.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104578.1" } ] } }, { "isoform_ac": "E1BG65-1", "url": "https://www.uniprot.org/uniprotkb/E1BG65/entry#E1BG65-1", "sequence": { "sequence": "MPRAPHFMPLLLLLLLSIPHTQAAFPQDPLPLLTSDLHGISPLSWFRGLEDDAVVAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKYLTWRSQDVENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAVFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVHALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVNLYGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGVAALFPSSRDLPDDVLTFIKAHPLLDPAVPPATHQPLLTLTSRALLTQVAVDGMAGPYSNITVLFLGSNDGTVLKVLPPGGQSGGSEPILLEEIDAYSPSRCSGKRAAQTARRVIGLELDTEGHRLFVAFSGCIIYLPLSRCARHGACRRSCLASQDPYCGWDSSRGCVDIRAPGGIDVDPTGNQESMEHDDCQDGATGSQSGTGDSTYVLLSPGPSPETPSPPSDAHPRPQSSTLGAHTQGVRRDLPPASASRSVPIPLLLACVAAAFALGASVSGLLVSCACRRAHRRRSKDIESAGIPRPLSLRSLARLHGAGPEPPPPSKDGEGAQTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRHAGGPWEWNQNGNNAKEGRSRARGGNAAGGAAPRVLVKPPPPGCPGQAVEVTTLEELLRYLHGPQAPRKEAEPPVAAPFTSRPLPPEPSPTLFAGPSLLPRDCAPPRRLDVPPEGKCPAPAARPALSAPAPRLGVGGSRKLPFSSHRAPPALLTRVPSGGPSRYSGGAGRHLLYLGRPEGHRGRALKRVEGREAPGAPEASLCRALLAGGRP", "length": 956, "header": "tr|E1BG65-1|E1BG65_BOVIN Isoform 1 of Semaphorin-6C OS=Bos taurus OX=9913 GN=SEMA6C PE=3 SV=3 CANONICAL=E1BG65-1" }, "locus": { "chromosome": "3", "start_pos": 19686177, "end_pos": 19677608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009575.6", "url": "https://www.ensembl.org/id/ENSBTAT00000009575.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009575.5", "url": "https://www.ensembl.org/id/ENSBTAP00000009575.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:524464", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524464", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AJG3-1", "protein_name": "Semaphorin 6C", "gene_name": "SEMA6C", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPPRAAAAPPLPLLVLVGPAALALSFPRDLEPRSAVGLSATASYPRFGGLRGDNGSAEFGIGFQRMLRLNGTLLVAARDHLYAFALGGDPTALYPHRSVTWEPRDRAGCAVRGEVQDGCHNHIRVLLPRDARTLFVCGTNAFSPVCRTYQALTLQQEGEELPGQARCPFDARQSIAATFADDRLYSATVADFQASDAVIYRSVRGPALRSIKYSSRWLREPHFVHAMPHGAHVYFFFREMAAELGLPGKVPVSRVGRVCRNDAGGSPRVLERRWTSFLKKRLQCAVPGDVPFHFDVLEAVTAPHTLHGQPAVLAVFGTQRNSIPGSAVCAFYLADVERAFEGPFADPRGAAAPWPPVPEERVPRPRPGCCAGMGSAAAIVTSGDIPDETLSFAKEHPLLHGAVVPAGGRPLFTQTGTRLTQLAVDVGAGPRGNHTVLFVGSEDGRVLKVLTAARRPGDNGQHGDTAGHGDGNGDNNGDNNGDGGTEAVLLEEIRLYEAGRCRGPRGASRVLGLELHPEGRELFVAFSGCIVRLPLSRCARHGQCRRSCLAARDPYCVWLPPGGCVPFSEDLPDGFEQDVEGSSGLTGTCAGAASAGDGDADNGDVAHRVRGAVPEAAVPVPVLVGCVLGAFVLGALVAGLGAACTRRPAAPKGAPEPPSPRPPPAPRLYPPLPPHSGAWDPHPELPSPEPSPEPPTRTPHGLSTPQPPGPGPPLRATLEGSGAAGWSLPPPGPMANRVQPGSSPFAPWDGAPRRLDVPPDSPPPPRRPLAQRHSLGGPGGAARPPGMARGLTRMYSLGAPGGAPPWGPHAIPLQRSLSMKPPLSTKPPLPPKPPPVP", "length": 837 }, "evidence": [ { "id": "E1BG65", "url": "https://omabrowser.org/oma/group/E1BG65/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SSX9-1", "protein_name": "Semaphorin-6C", "gene_name": "SEMA6C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPRTPYFMPLLLLLLLLSLPHTQAAFPQDPLPLLTSDLQGISPLSWFRGLEDDAVVAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKYLTWRSQDMENCAVRGKLTDECYNYIRVLVPWNSQTLLACGTNSFSPMCRSYGITSLQQEGEELSGQARCPFDATQSNVAVFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVHALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVNLYGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGVAALFPSSRDLPDDVLTFIKAHPLLDPAVPPATHQPLLTLTSRALLTQVAVDGMAGPYRNTTVLFLGSSDGTVLKVLPPGGQSGAHEPILLEEIDAYSPSRCSGKRAAQTARRVIGLELDTEGHRLFVAFSGCIIYLPLSRCARHGACRRSCLASQDPYCGWDSSRGCVDIRGPGGTDVDPAGKQESMEVDDCQDGATGSQSGTGDSTYGVRRDLPPASASRSVPIPLLLACVAAAFAMGASVSGLLVSCACRRAHRHRSKDIESPGLPRPLSLRSLARLHGAGPEPPPPPKDGEGALTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRHPGGPWEWNQNGNNAKEGRGRTRGGNATGGPAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPPRKEAEPPAAAPFTSRALPPEPTPSPTLFAGSCLLPRDCAPPRRLDVPPEGKGPAPAARPALSAPAPRLGVGGSRRLPFSTHRAPPALLTRVPSGGPSRYSGGAGKHLLYLGRPDGYRGRALKRVDVEKSQGPSKPPLVGPPSQQVVPNGSHFNF", "length": 934 }, "evidence": [ { "id": "E1BG65", "url": "https://omabrowser.org/oma/group/E1BG65/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9WTL3-1", "protein_name": "Semaphorin-6C", "gene_name": "Sema6c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRAPHSMPLLLLLLLSLPQAQTAFPQDPIPLLTSDLQGTSPSSWFRGLEDDAVAAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKFLTWRSQDMENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSTVAISAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVYALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQSLTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKEQRSLDGAWTPVSEDKVPSPRPGSCAGVGAAALFSSSQDLPDDVLLFIKAHPLLDPAVPPATHQPLLTLTSRALLTQVAVDGMAGPHRNTTVLFLGSNDGTVLKVLPPGGQSLGPEPIILEEIDAYSHARCSGKRSPRAARRIIGLELDTEGHRLFVAFPGCIVYLSLSRCARHGACQRSCLASLDPYCGWHRFRGCVNIRGPGGTDVDLTGNQESMEHGDCQDGATGSQSGPGDSAYVLLGPGPSPETPSSPSDAHPGPQSSTLGAHTQGVRRDLSPASASRSIPIPLLLACVAAAFALGASVSGLLVSCACRRANRRRSKDIETPGLPRPLSLRSLARLHGGGPEPPPPPKDGDAAQTPQLYTTFLPPPEGGSPPELACLPTPETTPELPVKHLRASGGPWEWNQNGNNASEGPGRPRGCSAAGGPAPRVLVRPPPPGCPGQEVEVTTLEELLRYLHGPQPPRKGSEPLASAPFTSRPPASEPGAALFVDSSPMPRDCVPPLRLDVPPDGKRAAPSGRPALSAPAPRLGVSGSRRLPFPTHRAPPGLLTRVPSGGPSRYSGGPGRHLLYLGRPDGHRGRSLKRVDVKSPLSPKPPLATPPQPAPHGSHFNF", "length": 960 }, "evidence": [ { "id": "E1BG65", "url": "https://omabrowser.org/oma/group/E1BG65/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WTM3-1", "protein_name": "Semaphorin-6C", "gene_name": "Sema6c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRAPHSMPLLLLLLLLSSLPQAQAAFPQDPTPLLTSDLQGASPSSWFRGLEDDAVAAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKFLTWRSQDMENCAVRGKLTDECYNYIRVLVPWNSQTLLACGTNSFSPMCRSYGITSLQQEGEELSGQARCPFDATQSTVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVYALEHGEHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQSLTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKEQRSLDGAWTPVSEDKVPSPRPGSCAGVGAAASFSSSQDLPDDVLLFIKAHPLLDPAVPPATHQPLLTLTSRALLTQVAVDGMAGPHRNTTVLFLGSNDGTVLKVLPPGGQSLGSEPIVLEEIDAYSHARCSGKRSPRAARRIIGLELDTEGHRLFVAFPGCIVYLSLSRCARHGACQRSCLASLDPYCGWHRSRGCMSIRGPGGTDVDLTGNQESTEHGDCQDGATGSQSGPGDSAYGVRRDLSPASASRSIPIPLLLACVAAAFALGASVSGLLVSCACRRANRRRSKDIETPGLPRPLSLRSLARLHGGGPEPPPPPKDGDAAQTPQLYTTFLPPPDGGSPPELACLPTPETTPELPVKHLRASGGPWEWNQNGNNASEGPGRPPRGCSGAGGPAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPPRKGSEPLASAPFTSRPPASEPGASLFVDSSPMPRDGVPPLRLDVPPEGKRAAPSGRPALSAPAPRLGVGGSRRLPFPTHRAPPGLLTRVPSGGPARYSGGPGRHLLYLGRPEGHRGRSLKRVDVKSPLSPKPPLASPPQPAPHGGHFNF", "length": 931 }, "evidence": [ { "id": "E1BG65", "url": "https://omabrowser.org/oma/group/E1BG65/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499", "evidence": [ { "database": "UniProtKB", "id": "E1BG65", "url": "https://www.uniprot.org/uniprotkb/E1BG65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BG65-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 956, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BG65-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BG65" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BG65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG65" }, { "id": "PS51004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sema", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 515, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 285, "end_pos": 287 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHP6-1", "uniprot_ac": "E1BHP6", "uniprot_id": "E1BHP6_BOVIN", "mass": { "chemical_mass": 49644.0, "monoisotopic_mass": 49644.0 }, "refseq": { "ac": "XP_010819358", "name": "E3 ubiquitin-protein ligase pellino homolog 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819358" }, "gene_names": [ { "name": "PELI3", "type": "recommended", "evidence": [ { "id": "E1BHP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP6" } ] }, { "name": "PELI3", "type": "synonym", "evidence": [ { "id": "XP_010819358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819358" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase pellino homolog", "type": "recommended", "evidence": [ { "id": "E1BHP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP6/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "E1BHP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP6/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase pellino homolog 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_010819358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819358" } ] } ], "function": [ { "annotation": "E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MK28", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK28#function" }, { "database": "UniProtKB", "id": "PIRNR038886", "url": "https://www.uniprot.org/uniprotkb/PIRNR038886#function" }, { "database": "UniProtKB", "id": "E1BHP6", "url": "https://www.uniprot.org/uniprotkb/E1BHP6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHP6", "url": "https://www.uniprot.org/uniprotkb/E1BHP6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PELI3", "url": "https://www.uniprot.org/uniprotkb/E1BHP6", "locus": { "chromosome": "29", "start_pos": 44518262, "end_pos": 44507848, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021097", "url": "https://www.ensembl.org/id/ENSBTAG00000021097" } ] } } ], "crossref": [ { "id": "E1BHP6", "url": "https://alphafold.ebi.ac.uk/entry/E1BHP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021097", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021097", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "504839", "url": "https://www.ncbi.nlm.nih.gov/gene/504839", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504839", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504839", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VICERWP", "url": "https://omabrowser.org/oma/group/VICERWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MK28", "url": "https://www.orthodb.org/?gene=A0A3Q1MK28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BHP6", "url": "https://www.orthodb.org/?gene=E1BHP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12098", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12098", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12098:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12098:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04710", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04710", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20723", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20723", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9020702", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9020702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-937039", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-937039", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-975144", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975144", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010819358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819358", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MK28", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MK28-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHP6", "url": "https://www.uniprot.org/uniprotkb/E1BHP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHP6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLEGNPEVGSPRTSDLQHPGNQGSCVLSSPSEDAQPGEEPIKYGELIVLGCCEEGGEETKAQRGEVAGPRAHSCYNGCLASGDKGRRRSRLALSRRPHANGVKPDVIHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTHDGDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD", "length": 460, "header": "tr|E1BHP6-1|E1BHP6_BOVIN Isoform 1 of E3 ubiquitin-protein ligase pellino homolog OS=Bos taurus OX=9913 GN=PELI3 PE=3 SV=3 CANONICAL=E1BHP6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MK28-1", "url": "https://www.uniprot.org/uniprotkb/E1BHP6/entry#A0A3Q1MK28-1", "sequence": { "sequence": "MVLEGNPEVGSPRTSDLQHPGNQGSCVLSSPSEDAQPGEEPIKYGELIVLGYNGCLASGDKGRRRSRLALSRRPHANGVKPDVIHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTHDGDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD", "length": 436, "header": "tr|A0A3Q1MK28-1|E1BHP6_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase pellino homolog OS=Bos taurus OX=9913 GN=PELI3 PE=3 SV=2 CANONICAL=E1BHP6-1" }, "locus": { "chromosome": "29", "start_pos": 44517258, "end_pos": 44509181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122370.2", "url": "https://www.ensembl.org/id/ENSBTAT00000122370.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083939.2", "url": "https://www.ensembl.org/id/ENSBTAP00000083939.2" } ] } }, { "isoform_ac": "E1BHP6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHP6/entry#E1BHP6-1", "sequence": { "sequence": "MVLEGNPEVGSPRTSDLQHPGNQGSCVLSSPSEDAQPGEEPIKYGELIVLGCCEEGGEETKAQRGEVAGPRAHSCYNGCLASGDKGRRRSRLALSRRPHANGVKPDVIHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTHDGDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD", "length": 460, "header": "tr|E1BHP6-1|E1BHP6_BOVIN Isoform 1 of E3 ubiquitin-protein ligase pellino homolog OS=Bos taurus OX=9913 GN=PELI3 PE=3 SV=3 CANONICAL=E1BHP6-1" }, "locus": { "chromosome": "29", "start_pos": 44517258, "end_pos": 44509181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028102.8", "url": "https://www.ensembl.org/id/ENSBTAT00000028102.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028102.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028102.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:504839", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504839", "resource": "KEGG Pathway" }, { "id": "R-BTA-9020702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9020702", "resource": "Reactome", "description": "Interleukin-1 signaling" }, { "id": "R-BTA-937039", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-937039", "resource": "Reactome", "description": "IRAK1 recruits IKK complex" }, { "id": "R-BTA-975144", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975144", "resource": "Reactome", "description": "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480L492-1", "protein_name": "E3 ubiquitin-protein ligase pellino homolog", "gene_name": "PELI3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLEGNPEVGSPRTSDLQHPENQGSCILSSPGEDAQPGEEPIKYGELIVLGCCEEGGEETEAQRGEVTGPRAHSCYNGCLASGDKGRRRSRLALNRRPHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD", "length": 469 }, "evidence": [ { "id": "E1BHP6", "url": "https://omabrowser.org/oma/group/E1BHP6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LEF3-1", "protein_name": "E3 ubiquitin-protein ligase pellino homolog", "gene_name": "Peli3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLEGNPDVGSPRTSDLQHPGSKGSCILSSPGEEALPGEEPIKYGELIVLGYNGCLASGDKGRRRSRLALSRRPHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGGGATEGPSAQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD", "length": 445 }, "evidence": [ { "id": "E1BHP6", "url": "https://omabrowser.org/oma/group/E1BHP6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7F7M5-1", "protein_name": "E3 ubiquitin-protein ligase pellino homolog 1", "gene_name": "peli3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLEGSSEALCPPPSLELRPSCNKNQSSPPLGSGSQSHDALCPEDKEPIKYGELIVLGHNGSLASGDKGRRRSRLALYKRPKANGVKPDVIHNVSTPLVSKALSNKSQHSISYTLSRSHSVIVEYTHDPNTDMFQIGRSTESMIDFVVTDTASSGGGGQGQGGAGGEGGQSAQSTISRYACRIMCERSAPYTARIYAAGFDSSKNIFLGERAAKWRTSDGLMDGLTTNGVLVMHPAGEFVSEPAPGVWREISVCGNVFALRETRSAQQRGKLVENESNMLQDGSLIDLCGATLLWRTPSGLRHTPTLKQLESLRQELNAARPQCPVGFNTLAFPSLAQRATIDKKQPWVYMNCGHVHGYHNWGFRKEKAGVAAVALTGGGGTAPATTGERECPMCRGVGPYVPLWLGCEGGLYLDAGPPTHAFCPCGHVCSEKTVQGWSQIPLPHGTHAFHAACPFCGTWLTGEQGYIKLIFQGPVD", "length": 477 }, "evidence": [ { "id": "E1BHP6", "url": "https://omabrowser.org/oma/group/E1BHP6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BXR6-1", "protein_name": "E3 ubiquitin-protein ligase pellino homolog 3", "gene_name": "Peli3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLEGNPDVGSPRTSDLQHPGSQGSCILSCPGEEALAGEEPIKYGELIVLGYNGCLASGDKGRRRSRLALSRRPHANGVKPDVMHHISTPLVSKALSNRGQHSISFTLSRSHSVIVEYTHDSDKDMFQIGRSTENMIDFVVTDTSPGGGATEGPSAQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGELGCVRLIFQGPLD", "length": 445 }, "evidence": [ { "id": "E1BHP6", "url": "https://omabrowser.org/oma/group/E1BHP6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N2H9-1", "protein_name": "E3 ubiquitin-protein ligase pellino homolog 3", "gene_name": "PELI3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLGCCEEGGEETEAQRGEVTGPRAHSCYNGCLASGDKGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD", "length": 469 }, "evidence": [ { "id": "E1BHP6", "url": "https://omabrowser.org/oma/group/E1BHP6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BHP6", "url": "https://www.uniprot.org/uniprotkb/E1BHP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "E1BHP6", "url": "https://www.uniprot.org/uniprotkb/E1BHP6" } ], "pmid": "" }, { "name": "regulation of Toll signaling pathway", "id": "GO:0008592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008592", "evidence": [ { "database": "UniProtKB", "id": "E1BHP6", "url": "https://www.uniprot.org/uniprotkb/E1BHP6" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "E1BHP6", "url": "https://www.uniprot.org/uniprotkb/E1BHP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-450690", "name": "hp-IRAK1,hp-IRAK4 bind Pellino1,2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1RMT8-1", "Q2LGB3-1", "E1BHP6-1" ], "evidence": [ { "id": "R-BTA-450690", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-450690" } ] }, { "id": "R-BTA-450827", "name": "hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1RMT8-1", "Q2LGB3-1", "E1BHP6-1" ], "evidence": [ { "id": "R-BTA-450827", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-450827" } ] }, { "id": "R-BTA-451418", "name": "Pellino ubiquitinates IRAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P5K3-1", "Q2LGB3-1", "E1BHP6-1" ], "evidence": [ { "id": "R-BTA-451418", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-451418" } ] }, { "id": "R-BTA-8948063", "name": "hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P5K3-1", "Q1RMT8-1", "Q2LGB3-1", "E1BHP6-1" ], "evidence": [ { "id": "R-BTA-8948063", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8948063" } ] }, { "id": "R-BTA-8948066", "name": "K63polyUb-IRAK1 dissociates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P5K3-1", "Q2LGB3-1", "E1BHP6-1" ], "evidence": [ { "id": "R-BTA-8948066", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8948066" } ] }, { "id": "R-BTA-937034", "name": "IRAK1 phosphorylates Pellino", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3ZCC3-1", "Q2LGB3-1", "E1BHP6-1" ], "evidence": [ { "id": "R-BTA-937034", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-937034" } ] }, { "id": "R-BTA-937044", "name": "Pellino binds hp-IRAK1:TRAF6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3ZCC3-1", "Q2LGB3-1", "E1BHP6-1" ], "evidence": [ { "id": "R-BTA-937044", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-937044" } ] }, { "id": "R-BTA-937050", "name": "Pellino ubiquitinates hp-IRAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp",
"cellular_location": "cytosol, plasma membrane",
"input_participant_list": [],
"output_participant_list": [],
"enzyme_list": [
"Q3ZCC3-1",
"Q0P5K3-1",
"Q2LGB3-1",
"E1BHP6-1"
],
"evidence": [
{
"id": "R-BTA-937050",
"database": "Reactome",
"url": "https://www.reactome.org/PathwayBrowser/#R-BTA-937050"
}
]
},
{
"id": "R-BTA-975122",
"name": "Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
",
"equation": "",
"summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3ZCC3-1", "Q0P5K3-1", "Q2LGB3-1", "E1BHP6-1" ], "evidence": [ { "id": "R-BTA-975122", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975122" } ] }, { "id": "R-BTA-975139", "name": "IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3ZCC3-1", "Q2LGB3-1", "E1BHP6-1" ], "evidence": [ { "id": "R-BTA-975139", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975139" } ] }, { "id": "R-BTA-975142", "name": "Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3ZCC3-1", "Q2LGB3-1", "E1BHP6-1" ], "evidence": [ { "id": "R-BTA-975142", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975142" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BHP6", "gene_name": "PELI3", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BHP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BHP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP6" } ] } ] }, { "uniprot_ac": "Q0P5K3", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q3ZCC3", "gene_name": "TRAF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q3ZCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCC3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q3ZCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCC3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHP6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 460, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHP6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHP6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP6" }, { "id": "PF04710", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04710" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pellino FHA", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 311, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BHP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP6" }, { "id": "PF20723", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20723" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pellino RING", "eco_id": "ECO_0000259", "start_pos": 317, "end_pos": 460, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJJ0-1", "uniprot_ac": "E1BJJ0", "uniprot_id": "E1BJJ0_BOVIN", "mass": { "chemical_mass": 53000.0, "monoisotopic_mass": 53000.0 }, "refseq": { "ac": "XP_010818068", "name": "monocarboxylate transporter 12 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818068" }, "gene_names": [ { "name": "SLC16A12", "type": "recommended", "evidence": [ { "id": "E1BJJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0" } ] }, { "name": "SLC16A12", "type": "synonym", "evidence": [ { "id": "XP_010818068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818068" } ] } ], "protein_names": [ { "name": "Monocarboxylate transporter 12", "type": "recommended", "evidence": [ { "id": "E1BJJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 16 member 12", "type": "synonym", "evidence": [ { "id": "E1BJJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0/entry#names_and_taxonomy" } ] }, { "name": "monocarboxylate transporter 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010818068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818068" } ] } ], "function": [ { "annotation": "Functions as a transporter for creatine and as well for its precursor guanidinoacetate. Transport of creatine and GAA is independent of resting membrane potential and extracellular Na(+), Cl(-), or pH. Contributes to the process of creatine biosynthesis and distribution.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MLG4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLG4#function" }, { "database": "UniProtKB", "id": "ARBA00037605", "url": "https://www.uniprot.org/uniprotkb/ARBA00037605#function" }, { "database": "UniProtKB", "id": "E1BJJ0", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJJ0", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC16A12", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0", "locus": { "chromosome": "26", "start_pos": 11104253, "end_pos": 11145436, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004662", "url": "https://www.ensembl.org/id/ENSBTAG00000004662" } ] } } ], "crossref": [ { "id": "E1BJJ0", "url": "https://alphafold.ebi.ac.uk/entry/E1BJJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004662", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004662", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17424", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17424", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538469", "url": "https://www.ncbi.nlm.nih.gov/gene/538469", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538469", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538469", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GSWMALT", "url": "https://omabrowser.org/oma/group/GSWMALT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MLG4", "url": "https://www.orthodb.org/?gene=A0A3Q1MLG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BJJ0", "url": "https://www.orthodb.org/?gene=E1BJJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360:SF318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360:SF318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010818068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818068", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "73043", "url": "https://www.rhea-db.org/rhea/73043", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73047", "url": "https://www.rhea-db.org/rhea/73047", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MLG4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MLG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJJ0", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJJ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKVKRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFSQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHFSCQVGIMLGGLLASTGLILGSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGISLSGSGIGIFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDQTTPEQNHVCRTQTQDFKQASPCSTWTKEWVQTCLCGSLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYFVPYALSVGVTHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAIGLDGLCYLCLPMLQSLPLLVPFACTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFSMIFSSLLLGFARVVKKMKRTQLRFLAKESDPKLQLWTNGSVAYSVARELDQRDGESVALAMLGSSPT", "length": 486, "header": "tr|E1BJJ0-1|E1BJJ0_BOVIN Isoform 1 of Monocarboxylate transporter 12 OS=Bos taurus OX=9913 GN=SLC16A12 PE=3 SV=1 CANONICAL=E1BJJ0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MLG4-1", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0/entry#A0A3Q1MLG4-1", "sequence": { "sequence": "MAKVKRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFSQDYAQTAWIHSIVDCVTMLCVGIMLGGLLASTGLILGSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGISLSGSGIGIFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDQTTPEQNHVCRTQTQDFKQASPCSTWTKEWVQTCLCGSLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYFVPYALSVGVTHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAIGLDGLCYLCLPMLQSLPLLVPFACTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFSMIFSSLLLGFARVVKKMKRTQLRFLAKESDPKLQLWTNGSVAYSVARELDQRDGESVALAMLGSSPT", "length": 472, "header": "tr|A0A3Q1MLG4-1|E1BJJ0_BOVIN Computationally mapped isoform of Monocarboxylate transporter 12 OS=Bos taurus OX=9913 GN=SLC16A12 PE=3 SV=2 CANONICAL=E1BJJ0-1" }, "locus": { "chromosome": "26", "start_pos": 11125409, "end_pos": 11105257, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076522.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076522.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071856.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071856.2" } ] } }, { "isoform_ac": "E1BJJ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0/entry#E1BJJ0-1", "sequence": { "sequence": "MAKVKRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFSQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHFSCQVGIMLGGLLASTGLILGSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGISLSGSGIGIFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDQTTPEQNHVCRTQTQDFKQASPCSTWTKEWVQTCLCGSLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYFVPYALSVGVTHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAIGLDGLCYLCLPMLQSLPLLVPFACTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFSMIFSSLLLGFARVVKKMKRTQLRFLAKESDPKLQLWTNGSVAYSVARELDQRDGESVALAMLGSSPT", "length": 486, "header": "tr|E1BJJ0-1|E1BJJ0_BOVIN Isoform 1 of Monocarboxylate transporter 12 OS=Bos taurus OX=9913 GN=SLC16A12 PE=3 SV=1 CANONICAL=E1BJJ0-1" }, "locus": { "chromosome": "26", "start_pos": 11125409, "end_pos": 11105257, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067650.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067650.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061923.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061923.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538469", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538469", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SCX9-1", "protein_name": "Monocarboxylate transporter 12", "gene_name": "SLC16A12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFSQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILGSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFNRRKALAYGISMSGSGIGIFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDRSTPEQNHVCRTQTQDLKQGSPCSTWTKKWVHTCLCGSLQQEYSFLLMSDFVVLAISVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGLDGLCYLCLPMLQSLPLLVPFACTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFSMIFSSVLLAFARLMKKMKKTQLRFLAKESDPKLQLWTNGSVAYSVTRELDQRDGESVAIAMLGSNLT", "length": 486 }, "evidence": [ { "id": "E1BJJ0", "url": "https://omabrowser.org/oma/group/E1BJJ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "E1BJJ0", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BJJ0", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "E1BJJ0", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0" } ], "pmid": "" }, { "name": "creatine transmembrane transporter activity", "id": "GO:0005308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005308", "evidence": [ { "database": "UniProtKB", "id": "E1BJJ0", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0" } ], "pmid": "" }, { "name": "uniporter activity", "id": "GO:0015292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015292", "evidence": [ { "database": "UniProtKB", "id": "E1BJJ0", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "creatine transmembrane transport", "id": "GO:0015881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015881", "evidence": [ { "database": "UniProtKB", "id": "E1BJJ0", "url": "https://www.uniprot.org/uniprotkb/E1BJJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "73043", "name": "", "equation": "creatine(in) = creatine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73043", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73043" } ] }, { "id": "73047", "name": "", "equation": "guanidinoacetate(in) = 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BI74-1", "uniprot_ac": "E1BI74", "uniprot_id": "E1BI74_BOVIN", "mass": { "chemical_mass": 33891.0, "monoisotopic_mass": 33891.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "type": "recommended", "evidence": [ { "id": "E1BI74", "database": "UniProtKB", "url": 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"https://alphafold.ebi.ac.uk/entry/E1BI74", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000026796", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000026796", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WEHRRQG", "url": "https://omabrowser.org/oma/group/WEHRRQG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10339:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10339:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19149", "url": "https://www.rhea-db.org/rhea/19149", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MMX1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI74", "url": "https://www.uniprot.org/uniprotkb/E1BI74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI74-1", "url": "https://www.uniprot.org/uniprotkb/E1BI74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAALLIALSCLSLHTLGSSVRPSVPWQNISIQNLSLAPDTFDDAYVGCSEEMEEKAVLLLEKEMADHALLRESWETAQKAWEQKRAGLTLPPGFRSQHGIAIMVYTNSSNTLYRELNQAVRTGGGSWESYMNHFPFKALHFYLTRALQLLRGGGGCSREPGQVVFRGVGTIRFEPKSVGDSIRLGQFTSSSLDETVARGFGNATFFSLRTCFGAPIQALSVFPKEREVLIPPHEVFVVTSFFKDGNNSLVTLSSSDQMCSHFNCAYLGEKKRLSCESVPSEQADSLSKGPFLCSPGRPCSWPLGGSSF", "length": 309, "header": "tr|E1BI74-1|E1BI74_BOVIN Isoform 1 of NAD(P)(+)--arginine ADP-ribosyltransferase OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=E1BI74-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MMX1-1", "url": "https://www.uniprot.org/uniprotkb/E1BI74/entry#A0A3Q1MMX1-1", "sequence": { "sequence": "MLAALLIALSCLSLHTLGSSVRPSVPWQNISIQNLSLAPDTFDDAYVGCSEEMEEKAVLLLEKEMADHALLRESWETAQKAWEQKRAGLTLPPGFRSQHGIAIMVYTNSSNTLYRELNQAVRTGGGSWESYMNHFPFKALHFYLTRALQLLRGGGGCSREPGQVVFRGVGTIRFEPKSVGDSIRLGQFTSSSLDETVARGFGNATFFSLRTCFGAPIQALSVFPKEREVLIPPHEVFVVTSFFKDGNNSLVTLSSSDQMCSHFNCAYLGGVLGTCDLQMKKGGFNEPGEATRWFQTQT", "length": 298, "header": "tr|A0A3Q1MMX1-1|E1BI74_BOVIN Computationally mapped isoform of NAD(P)(+)--arginine ADP-ribosyltransferase OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=E1BI74-1" }, "locus": { "chromosome": "15", "start_pos": 51514649, "end_pos": 51511666, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078388.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078388.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072541.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072541.2" } ] } }, { "isoform_ac": "E1BI74-1", "url": "https://www.uniprot.org/uniprotkb/E1BI74/entry#E1BI74-1", "sequence": { "sequence": "MLAALLIALSCLSLHTLGSSVRPSVPWQNISIQNLSLAPDTFDDAYVGCSEEMEEKAVLLLEKEMADHALLRESWETAQKAWEQKRAGLTLPPGFRSQHGIAIMVYTNSSNTLYRELNQAVRTGGGSWESYMNHFPFKALHFYLTRALQLLRGGGGCSREPGQVVFRGVGTIRFEPKSVGDSIRLGQFTSSSLDETVARGFGNATFFSLRTCFGAPIQALSVFPKEREVLIPPHEVFVVTSFFKDGNNSLVTLSSSDQMCSHFNCAYLGEKKRLSCESVPSEQADSLSKGPFLCSPGRPCSWPLGGSSF", "length": 309, "header": "tr|E1BI74-1|E1BI74_BOVIN Isoform 1 of NAD(P)(+)--arginine ADP-ribosyltransferase OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=E1BI74-1" }, "locus": { "chromosome": "15", "start_pos": 51514524, "end_pos": 51511666, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039859.6", "url": "https://www.ensembl.org/id/ENSBTAT00000039859.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039645.5", "url": "https://www.ensembl.org/id/ENSBTAP00000039645.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A061ICQ0-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MILEDLLMVLSCLGLHTLWKVQAVPILPLSLVPDTFDDAYVGCSEEMDEKAGLLLKEEMARHPLLRESWEAAQEAWEHRRHMLTLPPGFRAQHGIAIMVYTNSSNTLYWELNQAVRTGGGSRELYMRHFPFKALHFYLTRALQLLRDTGGCSRGDGEVVFRGVGSLHFEPKRLGDFVRLGQFTSSSLDETVARGFGNATFFSLRTCFGALIQALSVFPEEREVLIPPHEVFLVTGFFQDGAQRIVTLWSSNQTCSHFNCAYLGGEKRHGCVSSTTVGQPELSSTEALALRSGKTMLLAPGELQLSRAGP", "length": 309 }, "evidence": [ { "id": "E1BI74", "url": "https://omabrowser.org/oma/group/E1BI74/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SUY8-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "ART5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMLAALLIILSCTGLHTFRTPNPEAAPEARNVSLLSLAPDTFDDAYVGCSELMEEKAAPLLEEEMARHPQLRESWGTAQKAWERRRPGLSLPPGFQAQHGIAIMVYTNSSNTLYRELNRAVRTLGDSRESYMTRFPFKALHFYLTRGLQLLQSSGGCSRGPGETVFRGVSSLRFAPKGLGDSVRFGQFASSSKDEAVARRFGTATFFSLRTCFGAPIEALSVFPDEREVLILPHEVFFVTNFSQHGAQNLVTLSSGNQLCSYFNCAYLGEKKRLGCEPVPPRGQASSLFKGAFPLLVASWGFQLLGAGL", "length": 309 }, "evidence": [ { "id": "E1BI74", "url": "https://omabrowser.org/oma/group/E1BI74/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P70352-1", "protein_name": "Ecto-ADP-ribosyltransferase 5", "gene_name": "Art5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MILEDLLMVLSCLSLHALWKVRAVPILPLSLVPDTFDDAYVGCSEEMEEKAGLLLKEEMARHALLRESWEAAQEAWAHRRHKLTLPPGFKAQHGVAIMVYTNSSNTLYWELNQAVRTGGGSRELYMRHFPFKALHFYLTRALQLLRGSGGCSRGPGEVVFRGVGSLHFEPKRLGDSVRLGQFTSSSVDERVARRFGNATFFNLRTCFGAPIQALSVFPEEREVLIPPHEVFLVTGFSQDGAQSIVTLWSYDQTCSHFNCAYLGGEKRRGCVSSRAVGQPEAPSTEALALQSGKTLLLDPRKLQLSRAGP", "length": 309 }, "evidence": [ { "id": "E1BI74", "url": "https://omabrowser.org/oma/group/E1BI74/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5XHY4-1", "protein_name": "Ecto-ADP-ribosyltransferase 5", "gene_name": "Art5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILEDLLMVLSCLALHILWKVQAVPILPLSLVPDTFDDAYVGCSEEMEEKAGLLLKEEMARHALLRESWEAAQEAWAHGRHKLTLPPGFKAQHGVAVMVYTNSSNTLYWELNQAVRTGGRSRELYMRHFPFKALHFYLTRALQLLRGTGGCSREAGEVVFRGVSSLHFEPKRLGDSVRLGQFASSSVDERVARRFGNATFFNLRTCFGAPIQALSVFPEEREVLIPPHEVFLVTGFSQDGAQSIVTLWSYNQTCSHFNCAYLGGEKRRGCVSSRAGQPESFSTEALALQSGKTLLLAPGELQLSRAGP", "length": 308 }, "evidence": [ { "id": "E1BI74", "url": "https://omabrowser.org/oma/group/E1BI74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96L15-1", "protein_name": "Ecto-ADP-ribosyltransferase 5", "gene_name": "ART5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALAALMIALGSLGLHTWQAQAVPILPLGLAPDTFDDTYVGCAEEMEEKAAPLLKEEMAHHALLRESWEAAQETWEDKRRGLTLPPGFKAQNGIAIMVYTNSSNTLYWELNQAVRTGGGSRELYMRHFPFKALHFYLIRALQLLRGSGGCSRGPGEVVFRGVGSLRFEPKRLGDSVRLGQFASSSLDKAVAHRFGNATLFSLTTCFGAPIQAFSVFPKEREVLIPPHEVFLVTRFSQDGAQSLVTLWSYNQTCSHFNCAYLGGEKRRGCVSAPGALGTGDLHMTKRHLQQP", "length": 291 }, "evidence": [ { "id": "E1BI74", "url": "https://omabrowser.org/oma/group/E1BI74/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "E1BI74", "url": "https://www.uniprot.org/uniprotkb/E1BI74" } ], "pmid": "" }, { "name": "NAD+-protein-arginine ADP-ribosyltransferase activity", "id": "GO:0106274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106274", "evidence": [ { "database": "UniProtKB", "id": "E1BI74", "url": "https://www.uniprot.org/uniprotkb/E1BI74" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "E1BI74", "url": "https://www.uniprot.org/uniprotkb/E1BI74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19149", "name": "", "equation": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RR68-1", "E1BAP6-1", "E1BI74-1", "A0AAA9S718-1", "A0A3Q1MF93-1", "F1MHV9-1", "Q0VC22-1", "A0A3Q1MZC4-1", "A0AAA9SJA1-1" ], "evidence": [ { "id": "19149", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19149" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MF93", "gene_name": "LOC112441637", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0A3Q1MF93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF93" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0A3Q1MF93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF93" } ] } ] }, { "uniprot_ac": "A0A3Q1MZC4", "gene_name": "", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0A3Q1MZC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZC4" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0A3Q1MZC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZC4" } ] } ] }, { "uniprot_ac": "A0AAA9S718", "gene_name": "SMCO3", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0AAA9S718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S718" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0AAA9S718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S718" } ] } ] }, { "uniprot_ac": "A0AAA9SJA1", "gene_name": "SIRT6", "activity": [ { "ec_number": "2.3.1.286", "activity": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].", "evidence": [ { "id": "A0AAA9SJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA1" } ] }, { "ec_number": "2.3.1.286", "activity": "", "evidence": [ { "id": "A0AAA9SJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA1" } ] } ] }, { "uniprot_ac": "E1BAP6", "gene_name": "", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "E1BAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAP6" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "E1BAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAP6" } ] } ] }, { "uniprot_ac": "E1BI74", "gene_name": "", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "E1BI74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI74" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "E1BI74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI74" } ] } ] }, { "uniprot_ac": "F1MHV9", "gene_name": "LOC618664", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "F1MHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHV9" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "F1MHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHV9" } ] } ] }, { "uniprot_ac": "F6RR68", "gene_name": "ART1", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "F6RR68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RR68" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "F6RR68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RR68" } ] } ] }, { "uniprot_ac": "Q0VC22", "gene_name": "ART5", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "Q0VC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC22" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "Q0VC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC22" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BI74-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BI74-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BI74" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.2.31", "ec_name": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "2.4.2.31", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.31" }, { "id": "2.4.2.31", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.2.31" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"E1BKG4_BOVIN", "mass": { "chemical_mass": 150729.0, "monoisotopic_mass": 150729.0 }, "refseq": { "ac": "XP_024849312", "name": "sister chromatid cohesion protein PDS5 homolog A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849312" }, "gene_names": [ { "name": "PDS5A", "type": "recommended", "evidence": [ { "id": "E1BKG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKG4" } ] }, { "name": "PDS5A", "type": "synonym", "evidence": [ { "id": "XP_024849312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849312" } ] } ], "protein_names": [ { "name": "PDS5 cohesin associated factor A", "type": "synonym", "evidence": [ { "id": "E1BKG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKG4/entry#names_and_taxonomy" } ] }, { "name": "sister chromatid cohesion protein PDS5 homolog A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024849312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849312" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKG4", "url": "https://www.uniprot.org/uniprotkb/E1BKG4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PDS5A", "url": "https://www.uniprot.org/uniprotkb/E1BKG4", "locus": { "chromosome": "6", "start_pos": 58885510, "end_pos": 59019773, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017809", "url": "https://www.ensembl.org/id/ENSBTAG00000017809" } ] } } ], "crossref": [ { "id": "ENSBTAG00000017809", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017809", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19953", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19953", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "533206", "url": "https://www.ncbi.nlm.nih.gov/gene/533206", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:533206", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533206", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EKWEIVA", "url": "https://omabrowser.org/oma/group/EKWEIVA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKG4", "url": "https://www.orthodb.org/?gene=E1BKG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12663:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12663:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2468052", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2468052", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2470946", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2470946", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024849312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MP68", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MP68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MP68-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MP68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8D8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8D8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKG4", "url": "https://www.uniprot.org/uniprotkb/E1BKG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKG4-1", "url": "https://www.uniprot.org/uniprotkb/E1BKG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTKDAQSPDESKTNEKLYTVCDVALCVINSKSALCNAESPKDPVLPVKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGAETGSNINVNSELNPSTGNRPREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQSAQGNISSDRGKKRTVTAAGAENIQQKTDEKADESGPPAPSKPRRGRRPKSESQGNATKNDDINKPLSKGRKRAAVSQESPGGLEAGNAKAPKLQDTAKKAAPTERQIDLQR", "length": 1337, "header": "tr|E1BKG4-1|E1BKG4_BOVIN Isoform 1 of PDS5 cohesin associated factor A OS=Bos taurus OX=9913 GN=PDS5A PE=3 SV=3 CANONICAL=E1BKG4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MP68-1", "url": "https://www.uniprot.org/uniprotkb/E1BKG4/entry#A0A3Q1MP68-1", "sequence": { "sequence": "MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAIRLQQYMDHELPDVQAGFTKGRGTRNQIANILWIIEKAREFQENIYFCFIDYAKAFDCVDHHKLWKILKEMGIPDHLTCLFRNLALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTKDAQSPDESKTNEKLYTVCDVALCVINSKSALCNAESPKDPVLPVKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGAETGSNINVNSELNPSTGNRPREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQSAQGNISSDRGKKRTVTAAGAENIQQKTDEKADESGPPAPSKPRRGRRPKSESQGNATKNDDINKPLSKGRKRAAVSQESPGGLEAGNAKAPKLQDTAKKAAPTERQIDLQR", "length": 1419, "header": "tr|A0A3Q1MP68-1|E1BKG4_BOVIN Computationally mapped isoform of PDS5 cohesin associated factor A OS=Bos taurus OX=9913 GN=PDS5A PE=3 SV=2 CANONICAL=E1BKG4-1" }, "locus": { "chromosome": "6", "start_pos": 59018718, "end_pos": 58888380, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085347.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085347.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073674.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073674.2" } ] } }, { "isoform_ac": "A0AAA9T8D8-1", "url": "https://www.uniprot.org/uniprotkb/E1BKG4/entry#A0AAA9T8D8-1", "sequence": { "sequence": "MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTKDAQSPDESKTNEKLYTVCDVALCVINSKSALCNAESPKDPVLPVKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGAETGSNINVNSELNPSTGNRPREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQSAQGNISSDRGKKRTVTAAGAENIQQKTDEKADESGPPAPSKPRRGRRPKSESQGNATKNDDINKPLSKGRKRAAVSQESPGGLEAGNAKAPKLQDTAKKAAPTERQIDLQRFWTSHIPIRKQRPPSDF", "length": 1354, "header": "tr|A0AAA9T8D8-1|E1BKG4_BOVIN Computationally mapped isoform of PDS5 cohesin associated factor A OS=Bos taurus OX=9913 GN=PDS5A PE=3 SV=1 CANONICAL=E1BKG4-1" }, "locus": { "chromosome": "6", "start_pos": 59018718, "end_pos": 58885598, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087519.1", "url": "https://www.ensembl.org/id/ENSBTAT00000087519.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094999.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094999.1" } ] } }, { "isoform_ac": "E1BKG4-1", "url": "https://www.uniprot.org/uniprotkb/E1BKG4/entry#E1BKG4-1", "sequence": { "sequence": "MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTKDAQSPDESKTNEKLYTVCDVALCVINSKSALCNAESPKDPVLPVKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGAETGSNINVNSELNPSTGNRPREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQSAQGNISSDRGKKRTVTAAGAENIQQKTDEKADESGPPAPSKPRRGRRPKSESQGNATKNDDINKPLSKGRKRAAVSQESPGGLEAGNAKAPKLQDTAKKAAPTERQIDLQR", "length": 1337, "header": "tr|E1BKG4-1|E1BKG4_BOVIN Isoform 1 of PDS5 cohesin associated factor A OS=Bos taurus OX=9913 GN=PDS5A PE=3 SV=3 CANONICAL=E1BKG4-1" }, "locus": { "chromosome": "6", "start_pos": 59018718, "end_pos": 58888380, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023680.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023680.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023680.6", "url": "https://www.ensembl.org/id/ENSBTAP00000023680.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:533206", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533206", "resource": "KEGG Pathway" }, { "id": "R-BTA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-BTA-2468052", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2468052", "resource": "Reactome", "description": "Establishment of Sister Chromatid Cohesion" }, { "id": "R-BTA-2470946", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2470946", "resource": "Reactome", "description": "Cohesin Loading onto Chromatin" }, { "id": "R-BTA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BMZ8-1", "protein_name": "PDS5 cohesin associated factor A", "gene_name": "PDS5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTKDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGAETGSNINVNSELNPSTGNRSREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQAAQGNISSDRGKKRTVTAAGAENIQQKTDEKVDESGPPAPSKPRRGRRPKSESQGNATKNDDINKPLSKGRKRAAVSQESPGGLETGNAKAPKLQDVAKKAAPAERQIDLQRAVDEGRRERPQPSPSCRQRL", "length": 1357 }, "evidence": [ { "id": "E1BKG4", "url": "https://omabrowser.org/oma/group/E1BKG4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LFI0-1", "protein_name": "Sister chromatid cohesion protein PDS5 homolog A isoform X1", "gene_name": "Pds5a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFTQPKPAAALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLTLVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDSAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFSNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSAMCNADSPKDPVLPTKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPTGVLGTVNKPLSATGRKPYVRSAGAETGSNVNTNSELSPSAGSRSREQSSEASETGVSENEENPVRIISVTPVKNIDTVKNKEINSDQPTQGNISTDRGKKRIATAAGTENIQQKADEKVDESGPPAPSKPRRGRRPKSESQGNVTKNDDLNKPTSKGRKRAAGSQESPGGLEASNAKAPKQQDGAKKAAPAERQIDLQR", "length": 1336 }, "evidence": [ { "id": "E1BKG4", "url": "https://omabrowser.org/oma/group/E1BKG4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A4L9P7-1", "protein_name": "Sister chromatid cohesion protein PDS5 homolog A", "gene_name": "Pds5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFTQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDSAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFSNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDEAKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFSNDKSYISEETRVLLLTGKPKPTGVLGTVNKPLSATGRKPYVRSAGTETGSNINASSELSPSAGNRSREQSSEASETGVSENEENPVRIISVTPVKSIDTVKNKEINSDQSTQGNISSDRGKKRIVTAAGAENIQQKPDEKADESGPPAPSKPRRGRRPKSESQGNATKNDDLSKPVSKGRKRAAGSQESLEAGNAKAPKLQDGAKKAVPAERQIDLQR", "length": 1333 }, "evidence": [ { "id": "E1BKG4", "url": "https://omabrowser.org/oma/group/E1BKG4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q29RF7-1", "protein_name": "Sister chromatid cohesion protein PDS5 homolog A", "gene_name": "PDS5A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGTETGSNINVNSELNPSTGNRSREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQATQGNISSDRGKKRTVTAAGAENIQQKTDEKVDESGPPAPSKPRRGRRPKSESQGNATKNDDLNKPINKGRKRAAVGQESPGGLEAGNAKAPKLQDLAKKAAPAERQIDLQR", "length": 1337 }, "evidence": [ { "id": "E1BKG4", "url": "https://omabrowser.org/oma/group/E1BKG4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6A026-1", "protein_name": "Sister chromatid cohesion protein PDS5 homolog A", "gene_name": "Pds5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFTQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNTKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPQLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDSAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFSNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVYLLRLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPTGVLGTVNKPLSATGRKPYVRSAGTETGSNINANSELSPSAGSRSREQSSEASETGVSENEENPVRIISVTPVKNIDTVKNKEINSDQSTQGNISSDRGKKRIVTAAGAENIQKPDEKVDESGPPAPSKPRRGRRPKSESQGNATKNDDLNKPVSKGRKRAAGSQESLEAGNAKAPKLQDGAKKAVPAERQIDLQR", "length": 1332 }, "evidence": [ { "id": "E1BKG4", "url": "https://omabrowser.org/oma/group/E1BKG4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BKG4", "url": "https://www.uniprot.org/uniprotkb/E1BKG4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BKG4", "url": "https://www.uniprot.org/uniprotkb/E1BKG4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BKG4", "url": "https://www.uniprot.org/uniprotkb/E1BKG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E1BKG4", "url": "https://www.uniprot.org/uniprotkb/E1BKG4" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "E1BKG4", "url": "https://www.uniprot.org/uniprotkb/E1BKG4" } ], "pmid": "" }, { "name": "negative regulation of DNA replication", "id": "GO:0008156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008156", "evidence": [ { "database": "UniProtKB", "id": "E1BKG4", "url": "https://www.uniprot.org/uniprotkb/E1BKG4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cohesin unloader activity", "id": "GO:0140670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140670", "evidence": [ { "database": "UniProtKB", "id": "E1BKG4", "url": "https://www.uniprot.org/uniprotkb/E1BKG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1044, "end_pos": 1046, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1230, "end_pos": 1232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1281, "end_pos": 1283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 852, "end_pos": 854, "annotation": "n_glycosylation_sequon" }, { "start_pos": 858, "end_pos": 860, "annotation": "n_glycosylation_sequon" }, { "start_pos": 975, "end_pos": 977, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1044, "end_pos": 1046 }, { "start_pos": 1230, "end_pos": 1232 }, { "start_pos": 1281, "end_pos": 1283 }, { "start_pos": 176, "end_pos": 178 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 636, "end_pos": 638 }, { "start_pos": 852, "end_pos": 854 }, { "start_pos": 858, "end_pos": 860 }, { "start_pos": 975, "end_pos": 977 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDZ8-1", "uniprot_ac": "E1BDZ8", "uniprot_id": "E1BDZ8_BOVIN", "mass": { "chemical_mass": 91122.0, "monoisotopic_mass": 91122.0 }, "refseq": { "ac": "NP_001179171", "name": "enhancer of polycomb homolog 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179171" }, "gene_names": [ { "name": "EPC2", "type": "recommended", "evidence": [ { "id": "E1BDZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" } ] }, { "name": "EPC2", "type": "synonym", "evidence": [ { "id": "NP_001179171", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179171" } ] } ], "protein_names": [ { "name": "Enhancer of polycomb homolog", "type": "recommended", "evidence": [ { "id": "E1BDZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8/entry#names_and_taxonomy" } ] }, { "name": "enhancer of polycomb homolog 2", "type": "synonym", "evidence": [ { "id": "NP_001179171", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179171" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDZ8", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EPC2", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8", "locus": { "chromosome": "2", "start_pos": 47420198, "end_pos": 47680086, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018581", "url": "https://www.ensembl.org/id/ENSBTAG00000018581" } ] } } ], "crossref": [ { "id": "E1BDZ8", "url": "https://alphafold.ebi.ac.uk/entry/E1BDZ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018581", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018581", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539432", "url": "https://www.ncbi.nlm.nih.gov/gene/539432", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539432", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539432", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DQANHTC", "url": "https://omabrowser.org/oma/group/DQANHTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MPA3", "url": "https://www.orthodb.org/?gene=A0A3Q1MPA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BDZ8", "url": "https://www.orthodb.org/?gene=E1BDZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14898", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14898", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179171", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179171", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPA3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTS7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTS7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJA8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJA8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDZ8", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDZ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKINRSEKELYTTPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEAVLTSQQPTPETLPVINKSDLKQYDFHSSEEDEFPQVPSPASEPEEENDPDGPCAFRRRAGCQYYAPRLDQTNRSFGNSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRIATEHDPVLKQIDPEMLNGFSSASQNIDFSSNFSRTNASNKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNRRVSVASVALLNTSKNGISVSGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHSNINGVVQPSGTSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 807, "header": "tr|E1BDZ8-1|E1BDZ8_BOVIN Isoform 1 of Enhancer of polycomb homolog OS=Bos taurus OX=9913 GN=EPC2 PE=3 SV=1 CANONICAL=E1BDZ8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MPA3-1", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8/entry#A0A3Q1MPA3-1", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKINRSEKELYTTPATLHNGNHHKVQECKTKVPSPASEPEEENDPDGPCAFRRRAGCQYYAPRLDQTNRSFGNSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRIATEHDPVLKQIDPEMLNGFSSASQNIDFSSNFSRTNASNKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNRRVSVASVALLNTSKNGISVSGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHSNINGVVQPSGTSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 743, "header": "tr|A0A3Q1MPA3-1|E1BDZ8_BOVIN Computationally mapped isoform of Enhancer of polycomb homolog OS=Bos taurus OX=9913 GN=EPC2 PE=3 SV=1 CANONICAL=E1BDZ8-1" }, "locus": { "chromosome": "2", "start_pos": 47547236, "end_pos": 47421394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067897.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067897.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073717.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073717.1" } ] } }, { "isoform_ac": "A0AAA9RTS7-1", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8/entry#A0AAA9RTS7-1", "sequence": { "sequence": "MPREKANRRHLGGGLSASRMEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKINRSEKELYTTPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEAVLTSQQPTPETLPVINKSDLKQYDFHSSEEDEFPQVPSPASEPEEENDPDGPCAFRRRAGCQYYAPRLDQTNRSFGNSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRIATEHDPVLKQIDPEMLNGFSSASQNIDFSSNFSRTNASNKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNRRVSVASVALLNTSKNGISVSGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHSNINGVVQPSGTSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 776, "header": "tr|A0AAA9RTS7-1|E1BDZ8_BOVIN Computationally mapped isoform of Enhancer of polycomb homolog OS=Bos taurus OX=9913 GN=EPC2 PE=3 SV=1 CANONICAL=E1BDZ8-1" }, "locus": { "chromosome": "2", "start_pos": 47679887, "end_pos": 47421394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088486.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088486.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075387.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075387.1" } ] } }, { "isoform_ac": "A0AAA9SJA8-1", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8/entry#A0AAA9SJA8-1", "sequence": { "sequence": "MVFPLVMYACESWTVKNAECRRIDAFEVWCWRRLLRVPWTARRSNQSIVKEEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKINRSEKELYTTPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEAVLTSQQPTPETLPVINKSDLKQYDFHSSEEDEFPQVPSPASEPEEENDPDGPCAFRRRAGCQYYAPRLDQTNRSFGNSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRIATEHDPVLKQIDPEMLNGFSSASQNIDFSSNFSRTNASNKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNRRVSVASVALLNTSKNGISVSGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHSNINGVVQPSGTSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 807, "header": "tr|A0AAA9SJA8-1|E1BDZ8_BOVIN Computationally mapped isoform of Enhancer of polycomb homolog OS=Bos taurus OX=9913 GN=EPC2 PE=3 SV=1 CANONICAL=E1BDZ8-1" }, "locus": { "chromosome": "2", "start_pos": 47495467, "end_pos": 47421394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132732.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132732.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083893.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083893.1" } ] } }, { "isoform_ac": "E1BDZ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8/entry#E1BDZ8-1", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKINRSEKELYTTPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEAVLTSQQPTPETLPVINKSDLKQYDFHSSEEDEFPQVPSPASEPEEENDPDGPCAFRRRAGCQYYAPRLDQTNRSFGNSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRIATEHDPVLKQIDPEMLNGFSSASQNIDFSSNFSRTNASNKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNRRVSVASVALLNTSKNGISVSGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHSNINGVVQPSGTSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 807, "header": "tr|E1BDZ8-1|E1BDZ8_BOVIN Isoform 1 of Enhancer of polycomb homolog OS=Bos taurus OX=9913 GN=EPC2 PE=3 SV=1 CANONICAL=E1BDZ8-1" }, "locus": { "chromosome": "2", "start_pos": 47547236, "end_pos": 47421394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024730.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024730.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024730.5", "url": "https://www.ensembl.org/id/ENSBTAP00000024730.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539432", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539432", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y495-1", "protein_name": "Enhancer of polycomb homolog", "gene_name": "EPC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSSQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKLNRPEKEMSTTASTLHNGNHHKVPECKIKHPHHSSLKEEISDVVRQKKKYLKKPKMECVVTAQQPSAEPLPVINKSDIKQYDFHSSDEDEFPQVPSPVSEAEEENDPDGPCAFRRRAGCQYYAPRLDQTNSSYENSELAELDKLRFRHCLTTLTIPRRCIGFARRRVGRGGRVIMDRISTEHDPVLRQIDPEMLNSFSSSSQTLDFSSNFSRTNASNKRCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSISDCMSKTLDSASAHFAASAVVSAPAPGRSEATKEQTPSHNNINGVVQPSGTSRTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 807 }, "evidence": [ { "id": "E1BDZ8", "url": "https://omabrowser.org/oma/group/E1BDZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ADG5-1", "protein_name": "Enhancer of polycomb homolog", "gene_name": "Epc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRSEKELYASPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKHPKKPKAEAVLAPPQPTPETVPVINKSDIKQYDFQSSDEDEFPQVPSPASEPEEENDPDGPCAFRRRAGCQYYAPRLDQANNHPCESSELADLDKLRYKHCLTTLTVPRRCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGLSSSSQTIDFSSNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQDIDSEECTSRKPGQTVSSKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLAQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 808 }, "evidence": [ { "id": "E1BDZ8", "url": "https://omabrowser.org/oma/group/E1BDZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S0I9-1", "protein_name": "Enhancer of polycomb homolog", "gene_name": "EPC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKISRSEKELYATPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEALITSQQPTPETLPVINKSDIKQYDFHSSDEDEFPQVPSPVSEAEEENDPDGPCAFRRRAGCQYYAPRLDQINHSFENSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRIATEHDPVLKQIDPEMLNGFSSASQTIDFSSNFSRTNASSKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHNNINGVVQPSGTSKTLYSTNMALSSSPGISTVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 807 }, "evidence": [ { "id": "E1BDZ8", "url": "https://omabrowser.org/oma/group/E1BDZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q52LR7-1", "protein_name": "Enhancer of polycomb homolog 2", "gene_name": "EPC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKISRSEKELYATPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEALITSQQPTPETLPVINKSDIKQYDFHSSDEDEFPQVLSPVSEPEEENDPDGPCAFRRRAGCQYYAPRLDQANHSCENSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNSFSSSSQTIDFSSNFSRTNASSKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHNNINGVVQPSGTSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 807 }, "evidence": [ { "id": "E1BDZ8", "url": "https://omabrowser.org/oma/group/E1BDZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C0I4-1", "protein_name": "Enhancer of polycomb homolog 2", "gene_name": "Epc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRSEKELYASPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEAGIAPQQPTPETLPVINKSDIKQYDFQSSDEDEFPQVLSPASEAEEENDPDGSCAFRRRAGCQYYAPRLDQANNHMCENSELADLDKLRYKHCLTTLTVPRRCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGFSSSSQTIDFSSNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQDIDSEECTSRKPGQTVSSKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQRQQLAQLHQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGLAETTVAMEVT", "length": 808 }, "evidence": [ { "id": "E1BDZ8", "url": "https://omabrowser.org/oma/group/E1BDZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BDZ8", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "E1BDZ8", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" } ], "pmid": "" }, { "name": "piccolo histone acetyltransferase complex", "id": "GO:0032777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032777", "evidence": [ { "database": "UniProtKB", "id": "E1BDZ8", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BDZ8", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BDZ8", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "E1BDZ8", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "E1BDZ8", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "E1BDZ8", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BDZ8", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 723, "end_pos": 725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 735, "end_pos": 737, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDZ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 807, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDZ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDZ8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" }, { "id": "PF06752", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06752" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enhancer of polycomb C-terminal", "eco_id": "ECO_0000259", "start_pos": 578, "end_pos": 807, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BDZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDZ8" }, { "id": "PF10513", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10513" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enhancer of polycomb-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 148, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 289, "end_pos": 291 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 566, "end_pos": 568 }, { "start_pos": 723, "end_pos": 725 }, { "start_pos": 735, "end_pos": 737 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BL19-1", "uniprot_ac": "E1BL19", "uniprot_id": "E1BL19_BOVIN", "mass": { "chemical_mass": 55938.0, "monoisotopic_mass": 55938.0 }, "refseq": {}, "gene_names": [ { "name": "GPBP1L1", "type": "recommended", "evidence": [ { "id": "E1BL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL19" } ] } ], "protein_names": [ { "name": "GC-rich promoter binding protein 1 like 1", "type": "synonym", "evidence": [ { "id": "E1BL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL19/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], 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taurus OX=9913 GN=GPBP1L1 PE=3 SV=3 CANONICAL=E1BL19-1" }, "locus": { "chromosome": "3", "start_pos": 100452840, "end_pos": 100420738, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011603.6", "url": "https://www.ensembl.org/id/ENSBTAT00000011603.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011603.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011603.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BL19", "url": "https://www.uniprot.org/uniprotkb/E1BL19" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BL19", "url": "https://www.uniprot.org/uniprotkb/E1BL19" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BL19", "url": "https://www.uniprot.org/uniprotkb/E1BL19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BL19", "url": "https://www.uniprot.org/uniprotkb/E1BL19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BL19", "url": "https://www.uniprot.org/uniprotkb/E1BL19" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", 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"categories": [ "Protein" ] }, { "id": "A0A3Q1LPE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZZ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHB0", "url": "https://www.uniprot.org/uniprotkb/E1BHB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHB0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQPPPPPPAPPAAPQQPPGPPLQPQPPQLQQQQQQQPQHPLSQLTQLQSQPVHPGLLHSSPTAFRGPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGGRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEPEGQPLQLFSPSNPPEIIISSREDNHAHQTLLHHPNATHNHQHAGTTASSATFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCESPESATRLSHSSLPAWYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSALMEARGVSVAVGTTHTPLSDSPIGVSSTSFPTPYTSSSSC", "length": 736, "header": "tr|E1BHB0-1|E1BHB0_BOVIN Isoform 1 of Potassium calcium-activated channel subfamily N member 3 OS=Bos taurus OX=9913 GN=KCNN3 PE=4 SV=2 CANONICAL=E1BHB0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LH76-1", "url": "https://www.uniprot.org/uniprotkb/E1BHB0/entry#A0A3Q1LH76-1", "sequence": { "sequence": "MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQPPPPPPAPPAAPQQPPGPPLQPQPPQLQQQQQQQPQHPLSQLTQLQSQPVHPGLLHSSPTAFRGPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGGRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEPEGQPLQLFSPSNPPEIIISSREDNHAHQTLLHHPNATHNHQHAGTTASSATFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSALMEARGVSVAVGTTHTPLSDSPIGVPLLGSRKRR", "length": 715, "header": "tr|A0A3Q1LH76-1|E1BHB0_BOVIN Computationally mapped isoform of Potassium calcium-activated channel subfamily N member 3 OS=Bos taurus OX=9913 GN=KCNN3 PE=4 SV=1 CANONICAL=E1BHB0-1" }, "locus": { "chromosome": "3", "start_pos": 15891602, "end_pos": 15725419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084122.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084122.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058026.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058026.1" } ] } }, { "isoform_ac": "A0A3Q1LPE5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHB0/entry#A0A3Q1LPE5-1", "sequence": { "sequence": "MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQPPPPPPAPPAAPQQPPGPPLQPQPPQLQQQQQQQPQHPLSQLTQLQSQPVHPGLLHSSPTAFRGPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGGRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEPEGQPLQLFSPSNPPEIIISSREDNHAHQTLLHHPNATHNHQHAGTTASSATFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSALMEARGVSVAVGTTHTPLSDSPIGVSSTSFPTPYTSSSSC", "length": 689, "header": "tr|A0A3Q1LPE5-1|E1BHB0_BOVIN Computationally mapped isoform of Potassium calcium-activated channel subfamily N member 3 OS=Bos taurus OX=9913 GN=KCNN3 PE=4 SV=2 CANONICAL=E1BHB0-1" }, "locus": { "chromosome": "3", "start_pos": 15891373, "end_pos": 15725419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068409.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068409.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056788.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056788.2" } ] } }, { "isoform_ac": "A0AAA9RZZ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHB0/entry#A0AAA9RZZ6-1", "sequence": { "sequence": "MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQPPPPPPAPPAAPQQPPGPPLQPQPPQLQQQQQQQPQHPLSQLTQLQSQPVHPGLLHSSPTAFRGPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGGRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEPEGQPLQLFSPSNPPEIIISSREDNHAHQTLLHHPNATHNHQHAGTTASSATFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKSSQLKLFWPPVRNGGRCISFYLMKMPKKRALLSEPYSRSAFLALNCHKYCKETRSFCESLD", "length": 684, "header": "tr|A0AAA9RZZ6-1|E1BHB0_BOVIN Computationally mapped isoform of Potassium calcium-activated channel subfamily N member 3 OS=Bos taurus OX=9913 GN=KCNN3 PE=4 SV=1 CANONICAL=E1BHB0-1" }, "locus": { "chromosome": "3", "start_pos": 15885524, "end_pos": 15725419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128412.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128412.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076942.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076942.1" } ] } }, { "isoform_ac": "E1BHB0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHB0/entry#E1BHB0-1", "sequence": { "sequence": "MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQPPPPPPAPPAAPQQPPGPPLQPQPPQLQQQQQQQPQHPLSQLTQLQSQPVHPGLLHSSPTAFRGPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGGRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEPEGQPLQLFSPSNPPEIIISSREDNHAHQTLLHHPNATHNHQHAGTTASSATFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCESPESATRLSHSSLPAWYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSALMEARGVSVAVGTTHTPLSDSPIGVSSTSFPTPYTSSSSC", "length": 736, "header": "tr|E1BHB0-1|E1BHB0_BOVIN Isoform 1 of Potassium calcium-activated channel subfamily N member 3 OS=Bos taurus OX=9913 GN=KCNN3 PE=4 SV=2 CANONICAL=E1BHB0-1" }, "locus": { "chromosome": "3", "start_pos": 15891373, "end_pos": 15725419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024292.5", "url": "https://www.ensembl.org/id/ENSBTAT00000024292.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024292.4", "url": "https://www.ensembl.org/id/ENSBTAP00000024292.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1296052", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296052", "resource": "Reactome", "description": "Ca2+ activated K+ channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "E1BHB0", "url": "https://www.uniprot.org/uniprotkb/E1BHB0" } ], "pmid": "" }, { "name": "small conductance calcium-activated potassium channel activity", "id": "GO:0016286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016286", "evidence": [ { "database": "UniProtKB", "id": "E1BHB0", "url": "https://www.uniprot.org/uniprotkb/E1BHB0" } ], "pmid": "" }, { "name": "inward rectifier potassium channel activity", "id": "GO:0005242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005242", "evidence": [ { "database": "UniProtKB", "id": "E1BHB0", "url": "https://www.uniprot.org/uniprotkb/E1BHB0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BHB0", "url": "https://www.uniprot.org/uniprotkb/E1BHB0" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "E1BHB0", "url": "https://www.uniprot.org/uniprotkb/E1BHB0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BHB0", "url": "https://www.uniprot.org/uniprotkb/E1BHB0" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "E1BHB0", "url": "https://www.uniprot.org/uniprotkb/E1BHB0" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "E1BHB0", "url": "https://www.uniprot.org/uniprotkb/E1BHB0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "E1BHB0", "url": "https://www.uniprot.org/uniprotkb/E1BHB0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHB0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 736, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHB0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHB0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHB0" }, { "id": "SM01053", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calmodulin-binding", "eco_id": "ECO_0000259", "start_pos": 566, "end_pos": 642, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 228, "end_pos": 230 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGJ4-1", "uniprot_ac": "E1BGJ4", "uniprot_id": "E1BGJ4_BOVIN", "mass": { "chemical_mass": 137064.0, "monoisotopic_mass": 137064.0 }, "refseq": { "ac": "XP_059735055", "name": "alpha-mannosidase 2x isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059735055" }, "gene_names": [ { "name": "MAN2A2", "type": "recommended", "evidence": [ { "id": "E1BGJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" } ] }, { "name": "MAN2A2", "type": "synonym", "evidence": [ { "id": "XP_059735055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059735055" } ] } ], "protein_names": [ { "name": "Alpha-mannosidase", "type": "recommended", "evidence": [ { "id": "E1BGJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.-", "type": "synonym", "evidence": [ { "id": "E1BGJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4/entry#names_and_taxonomy" } ] }, { "name": "alpha-mannosidase 2x isoform X3", "type": "synonym", "evidence": [ { "id": "XP_059735055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059735055" } ] } ], "function": [ { "annotation": "Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LI72", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI72#function" }, { "database": "UniProtKB", "id": "ARBA00059516", "url": "https://www.uniprot.org/uniprotkb/ARBA00059516#function" }, { "database": "UniProtKB", "id": "E1BGJ4", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4#function" }, { "database": "UniProtKB", "id": "A0A3Q1M671", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M671#function" }, { "database": "UniProtKB", "id": "A0AAA9TAH8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAH8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGJ4", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MAN2A2", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4", "locus": { "chromosome": "21", "start_pos": 21741603, "end_pos": 21766521, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018905", "url": "https://www.ensembl.org/id/ENSBTAG00000018905" } ] } } ], "crossref": [ { "id": "E1BGJ4", "url": "https://alphafold.ebi.ac.uk/entry/E1BGJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018905", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018905", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "527449", "url": "https://www.ncbi.nlm.nih.gov/gene/527449", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "1341413", "url": "https://www.iedb.org/epitope/1341413", "database": "IEDB", "categories": [ "Other" ] }, { "id": "IPR000602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:527449", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527449", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LI72", "url": "https://www.orthodb.org/?gene=A0A3Q1LI72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M671", "url": "https://www.orthodb.org/?gene=A0A3Q1M671", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BGJ4", "url": "https://www.orthodb.org/?gene=E1BGJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11607", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11607", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11607:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11607:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01074", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01074", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07748", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07748", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-975578", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975578", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_059735055", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059735055", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LI72", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LI72-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M671", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M671", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M671-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M671-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAH8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAH8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGJ4", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGJ4-1", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPCQVVTEHEKLLFLWSQANWCPAGAGTHWDIWWKDHHGIFACRSYICCPSSQVCVEASMKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPARHQNGGNFPRSQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTANVEGPPALLPYYVANGSWVVPPEPRPSFFSISPQDCQFALGGRGPKPELQMLTISEELPFDNVDGGVWKQGFDISYSPHDWDSEDLQVFVVPHSHNDPGWLKTFDKYYTEQTQHILNNMVSKLQEDPRRRFIWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLEKNLGATPRSGWAVDPFGYSPTMPYLLRRANLTSMLIQRVHYAIKKHFAASHSLEFMWRQTWDSDASTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRISCPWKVPPRAITEANVAERAGLLLDQYRKKSRLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFLNSKPDLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKNLDRVLEAHLRGAEILYSLAVAHARRAGLASQFPLSNFALLTDARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVSLKQVIMNAAHYLVLGDKKTYHFDPEVPFLQMDDTRLNHDALPERTVIQLESSPRYVVLFNPLEQERLSVVSLLVSSPRVRVLSEEGQPLAVQVSAHWSSATDMVPDVYQVSVPVRLPALGLGVLQLQQGLDGPRTLPSSVRVYLHGRPLSVSRNEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSVRRVDEEQEQRVDMEFLVYGTRSSKDKSGAYLFLPDGEAKPYVPRDPPVLRVTEGPFFSEVVACYEHVHQVVRLYNLPGVEGLSLDVSSLVDIRDYVNKELALRIRTDINSQGIFFTDLNGFQVQPRRYLKKLPLQANFYPMPVMAYLQDAQNRLTLHTAQALGVSSLHDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNHFRLLLERRTPGREVREAASASFPSLLSHLTSMYLNTPVLALPVARRQAPGPALRSFHPLASSLPCDFHLLNLRTLQAEEDGLPSAETALLLHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYVEPMEITTFRLRLG", "length": 1210, "header": "tr|E1BGJ4-1|E1BGJ4_BOVIN Isoform 1 of Alpha-mannosidase OS=Bos taurus OX=9913 GN=MAN2A2 PE=3 SV=2 CANONICAL=E1BGJ4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LI72-1", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4/entry#A0A3Q1LI72-1", "sequence": { "sequence": "MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPARHQNGGNFPRSQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTANVEGPPALLPYYVANGSWVVPPEPRPSFFSISPQDCQFALGGRGPKPELQMLTISEELPFDNVDGGVWKQGFDISYSPHDWDSEDLQVFVVPHSHNDPGWLKTFDKYYTEQTQHILNNMVSKLQEDPRRRFIWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLEKNLGATPRSGWAVDPFGYSPTMPYLLRRANLTSMLIQRVHYAIKKHFAASHSLEFMWRQTWDSDASTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRISCPWKVPPRAITEANVAERAGLLLDQYRKKSRLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFLNSKPDLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKNLDRVLEAHLRGAEILYSLAVAHARRAGLASQFPLSNFALLTDARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVSLKQVIMNAAHYLVLGDKKTYHFDPEVPFLQMDDTRLNHDALPERTVIQLESSPRYVVLFNPLEQERLSVVSLLVSSPRVRVLSEEGQPLAVQVSAHWSSATDMVPDVYQVSVPVRLPALGLGVLQLQQGLDGPRTLPSSVRVYLHGRPLSVSRNEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSVRRVDEEQEQRVDMEFLVYGTRSSKDKSGAYLFLPDGEAKPYVPRDPPVLRVTEGPFFSEVVACYEHVHQVVRLYNLPGVEGLSLDVSSLVDIRDYVNKELALRIRTDINSQGIFFTDLNGFQVQPRRYLKKLPLQANFYPMPVMAYLQDAQNRLTLHTAQALGVSSLHDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNHFRLLLERRTPGREVREAASASFPSLLSHLTSMYLNTPVLALPVARRQAPGPALRSFHPLASSLPCDFHLLNLRTLQAEEDGLPSAETALLLHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYVEPMEITTFRLRLG", "length": 1150, "header": "tr|A0A3Q1LI72-1|E1BGJ4_BOVIN Computationally mapped isoform of Alpha-mannosidase OS=Bos taurus OX=9913 GN=MAN2A2 PE=3 SV=2 CANONICAL=E1BGJ4-1" }, "locus": { "chromosome": "21", "start_pos": 21758884, "end_pos": 21742691, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080016.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080016.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058647.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058647.2" } ] } }, { "isoform_ac": "A0A3Q1M671-1", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4/entry#A0A3Q1M671-1", "sequence": { "sequence": "MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPARHQNGGNFPRSQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTANVEGPPALLPYYVANGSWVVPPEPRPSFFSISPQDCQFALGGRGPKPELQMLTISEELPFDNVDGGVWKQGFDISYSPHDWDSEDLQVFVVPHSHNDPGWLKTFDKYYTEQTQHILNNMVSKLQEDPRRRFIWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLEKNLGATPRSGWAVDPFGYSPTMPYLLRRANLTSMLIQRVHYAIKKHFAASHSLEFMWRQTWDSDASTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRISCPWKVPPRAITEANVAERAGLLLDQYRKKSRLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFLNSKPDLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKNLDRVLEAHLRGAEILYSLAVAHARRAGLASQFPLSNFALLTDARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVSLKQVIMNAAHYLVLGDKKTYHFDPEVPFLQMDDTRLNHDALPERTVIQLESSPRYVVLFNPLEQERLSVVSLLVSVPVRLPALGLGVLQLQQGLDGPRTLPSSVRVYLHGRPLSVSRNEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSVRRVDEEQEQRVDMEFLVYGTRSSKDKSGAYLFLPDGEAKPYVPRDPPVLRVTEGPFFSEVVACYEHVHQVVRLYNLPGVEGLSLDVSSLVDIRDYVNKELALRIRTDINSQGIFFTDLNGFQVQPRRYLKKLPLQANFYPMPVMAYLQDAQNRLTLHTAQALGVSSLHDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNHFRLLLERRTPGREVREAASASFPSLLSHLTSMYLNTPVLALPVARRQAPGPALRSFHPLASSLPCDFHLLNLRTLQAEEDGLPSAETALLLHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYVEPMEITTFRLRLG", "length": 1114, "header": "tr|A0A3Q1M671-1|E1BGJ4_BOVIN Computationally mapped isoform of Alpha-mannosidase OS=Bos taurus OX=9913 GN=MAN2A2 PE=3 SV=3 CANONICAL=E1BGJ4-1" }, "locus": { "chromosome": "21", "start_pos": 21758884, "end_pos": 21742691, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071300.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071300.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065459.3", "url": "https://www.ensembl.org/id/ENSBTAP00000065459.3" } ] } }, { "isoform_ac": "A0AAA9TAH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4/entry#A0AAA9TAH8-1", "sequence": { "sequence": "MLDHIKAKRKKNGTNIQEKNNRSRPTNDPNIGFGSQVCVEASMKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPARHQNGGNFPRSQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTANVEGPPALLPYYVANGSWVVPPEPRPSFFSISPQDCQFALGGRGPKPELQMLTISEELPFDNVDGGVWKQGFDISYSPHDWDSEDLQVFVVPHSHNDPGWLKTFDKYYTEQTQHILNNMVSKLQEDPRRRFIWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLEKNLGATPRSGWAVDPFGYSPTMPYLLRRANLTSMLIQRVHYAIKKHFAASHSLEFMWRQTWDSDASTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRISCPWKVPPRAITEANVAERAGLLLDQYRKKSRLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFLNSKPDLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKNLDRVLEAHLRGAEILYSLAVAHARRAGLASQFPLSNFALLTDARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVSLKQVIMNAAHYLVLGDKKTYHFDPEVPFLQMDDTRLNHDALPERTVIQLESSPRYVVLFNPLEQERLSVVSLLVSSPRVRVLSEEGQPLAVQVSAHWSSATDMVPDVYQVSVPVRLPALGLGVLQLQQGLDGPRTLPSSVRVYLHGRPLSVSRNEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSVRRVDEEQEQRVDMEFLVYGTRSSKDKSGAYLFLPDGEAKPYVPRDPPVLRVTEGPFFSEVVACYEHVHQVVRLYNLPGVEGLSLDVSSLVDIRDYVNKELALRIRTDINSQGIFFTDLNGFQVQPRRYLKKLPLQANFYPMPVMAYLQDAQNRLTLHTAQALGVSSLHDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNHFRLLLERRTPGREVREAASASFPSLLSHLTSMYLNTPVLALPVARRQAPGPALRSFHPLASSLPCDFHLLNLRTLQAEEDGLPSAETALLLHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYVEPMEITTFRLRLG", "length": 1192, "header": "tr|A0AAA9TAH8-1|E1BGJ4_BOVIN Computationally mapped isoform of Alpha-mannosidase OS=Bos taurus OX=9913 GN=MAN2A2 PE=3 SV=1 CANONICAL=E1BGJ4-1" }, "locus": { "chromosome": "21", "start_pos": 21766429, "end_pos": 21742691, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105161.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105161.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093010.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093010.1" } ] } }, { "isoform_ac": "E1BGJ4-1", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4/entry#E1BGJ4-1", "sequence": { "sequence": "MPPCQVVTEHEKLLFLWSQANWCPAGAGTHWDIWWKDHHGIFACRSYICCPSSQVCVEASMKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPARHQNGGNFPRSQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTANVEGPPALLPYYVANGSWVVPPEPRPSFFSISPQDCQFALGGRGPKPELQMLTISEELPFDNVDGGVWKQGFDISYSPHDWDSEDLQVFVVPHSHNDPGWLKTFDKYYTEQTQHILNNMVSKLQEDPRRRFIWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLEKNLGATPRSGWAVDPFGYSPTMPYLLRRANLTSMLIQRVHYAIKKHFAASHSLEFMWRQTWDSDASTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRISCPWKVPPRAITEANVAERAGLLLDQYRKKSRLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFLNSKPDLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKNLDRVLEAHLRGAEILYSLAVAHARRAGLASQFPLSNFALLTDARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVSLKQVIMNAAHYLVLGDKKTYHFDPEVPFLQMDDTRLNHDALPERTVIQLESSPRYVVLFNPLEQERLSVVSLLVSSPRVRVLSEEGQPLAVQVSAHWSSATDMVPDVYQVSVPVRLPALGLGVLQLQQGLDGPRTLPSSVRVYLHGRPLSVSRNEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSVRRVDEEQEQRVDMEFLVYGTRSSKDKSGAYLFLPDGEAKPYVPRDPPVLRVTEGPFFSEVVACYEHVHQVVRLYNLPGVEGLSLDVSSLVDIRDYVNKELALRIRTDINSQGIFFTDLNGFQVQPRRYLKKLPLQANFYPMPVMAYLQDAQNRLTLHTAQALGVSSLHDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNHFRLLLERRTPGREVREAASASFPSLLSHLTSMYLNTPVLALPVARRQAPGPALRSFHPLASSLPCDFHLLNLRTLQAEEDGLPSAETALLLHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYVEPMEITTFRLRLG", "length": 1210, "header": "tr|E1BGJ4-1|E1BGJ4_BOVIN Isoform 1 of Alpha-mannosidase OS=Bos taurus OX=9913 GN=MAN2A2 PE=3 SV=2 CANONICAL=E1BGJ4-1" }, "locus": { "chromosome": "21", "start_pos": 21759064, "end_pos": 21742691, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025161.6", "url": "https://www.ensembl.org/id/ENSBTAT00000025161.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025161.5", "url": "https://www.ensembl.org/id/ENSBTAP00000025161.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "HLA-DO Modulates the Diversity of the MHC-II Self-peptidome.", "journal": "Molecular & cellular proteomics : MCP", "date": "2019-03", "authors": "Nanaware Padma P, Jurewicz Mollie M, Leszyk John D, Shaffer Scott A, Stern Lawrence J", "evidence": [ { "database": "IEDB", "id": "1341413", "url": "https://www.iedb.org/epitope/1341413" } ], "reference": [ { "type": "PubMed", "id": "30573663", "url": "https://glygen.org/publication/PubMed/30573663" } ] } ], "pathway": [ { "id": "bta:527449", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527449", "resource": "KEGG Pathway" }, { "id": "R-BTA-975578", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975578", "resource": "Reactome", "description": "Reactions specific to the complex N-glycan synthesis pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ4", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ4", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ4", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" } ], "pmid": "" }, { "name": "mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity", "id": "GO:0004572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004572", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ4", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" } ], "pmid": "" }, { "name": "alpha-mannosidase activity", "id": "GO:0004559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004559", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ4", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" } ], "pmid": "" }, { "name": "hydrolase activity, hydrolyzing N-glycosyl compounds", "id": "GO:0016799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016799", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ4", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mannose metabolic process", "id": "GO:0006013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006013", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ4", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ4", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1153, "end_pos": 1155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1191, "end_pos": 1193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-975814", "name": "Trimming of mannoses on the alpha1,6 arm by MAN2A1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-964837" ], "output_participant_list": [ "R-ALL-964752" ], "enzyme_list": [ "A0AAA9SXF2-1", "E1BGJ4-1" ], "evidence": [ { "id": "R-BTA-975814", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975814" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-964752", "participant_name": "Man [Golgi lumen]", "crossref": [ { "id": "4650", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000003830679", "database": "ZINC", "url": "" }, { "id": "4208", "database": "ChEBI", "url": "" }, { "id": "G70323CJ", "database": "GlyTouCan", "url": "" }, { "id": "C00159", "database": "COMPOUND", "url": "" }, { "id": "ZINC000003860903", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-964837", "participant_name": "(GlcNAc)3 (Man)5 (Asn)1 [Golgi lumen]", "crossref": [ { "id": "60625", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9SXF2", "gene_name": "MAN2A1", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "A0AAA9SXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXF2" } ] } ] }, { "uniprot_ac": "E1BGJ4", "gene_name": "MAN2A2", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "E1BGJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGJ4" }, { "id": "SM00872", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00872" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycoside hydrolase family 38 central", "eco_id": "ECO_0000259", "start_pos": 562, "end_pos": 648, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1153, "end_pos": 1155 }, { "start_pos": 1191, "end_pos": 1193 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 365, "end_pos": 367 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1BHL8-1", "uniprot_ac": "E1BHL8", "uniprot_id": "E1BHL8_BOVIN", "mass": { "chemical_mass": 44979.0, "monoisotopic_mass": 44979.0 }, "refseq": {}, "gene_names": [ { "name": "TNFRSF25", "type": "recommended", "evidence": [ { "id": "E1BHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL8" } ] } ], "protein_names": [ { "name": "TNF receptor superfamily member 25", "type": "synonym", "evidence": [ { "id": "E1BHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHL8", "url": "https://www.uniprot.org/uniprotkb/E1BHL8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TNFRSF25", "url": "https://www.uniprot.org/uniprotkb/E1BHL8", "locus": { "chromosome": "16", "start_pos": 46909417, "end_pos": 46904983, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006519", "url": "https://www.ensembl.org/id/ENSBTAG00000006519" } ] } } ], "crossref": [ { "id": "E1BHL8", "url": "https://alphafold.ebi.ac.uk/entry/E1BHL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006519", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006519", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13420", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13420", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "783432", "url": "https://www.ncbi.nlm.nih.gov/gene/783432", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001368", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001368", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GVFWVQV", "url": "https://omabrowser.org/oma/group/GVFWVQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LIC4", "url": "https://www.orthodb.org/?gene=A0A3Q1LIC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BHL8", "url": "https://www.orthodb.org/?gene=E1BHL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47220:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47220:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5669034", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5669034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LIC4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LIC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHL8", "url": "https://www.uniprot.org/uniprotkb/E1BHL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHL8-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRPRPGTSAAAAAAALLFLLLLGARASTPSPRCDCGHSFPKRSGLGCCKGCPAGHYLKAPCTKPCGAATCLPCPQGTFLARENHYETRCARCQACDELAPQMALRNCSAVADTHCGCRPGWFMDCMVSQCRHGSPFRCRPCTDCGALHRHTQTPCSSRDTHCGTCLPGFYEYDKSCVSCPTSTLGSCPEPCVAVCGWRQMFWVQMLVAGLVVPLLLGATLTYTYHRCHPCKAIGPADDTGVEVWTPLQTTHLSPPDSGPALLVTPSSSEKVCPVHLVGHSCTSGSPQTQEAPCLEATWSWDQLPSRAPGLPPPPSPAPPAGSAAATLQPGPQLYDVMDAVPARRWKEFMRTLGLREAEIEAVEVEVGRFRDQQYEMLKRWRQQQHAGLGAVYAALERMGLDGCAEDLRSRLQRGP", "length": 417, "header": "tr|E1BHL8-1|E1BHL8_BOVIN Isoform 1 of TNF receptor superfamily member 25 OS=Bos taurus OX=9913 GN=TNFRSF25 PE=4 SV=2 CANONICAL=E1BHL8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LIC4-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL8/entry#A0A3Q1LIC4-1", "sequence": { "sequence": "MGTSSAQEPGKWAALRASARVGETGQREAPAWAARLGVSSPCPQALLFLLLLGARASTPSPRCDCGHSFPKRSGLGCCKGCPAGHYLKAPCTKPCGAATCLPCPQGTFLARENHYETRCARCQACDELAPQMALRNCSAVADTHCGCRPGWFMDCMVSQCRHGSPFRCRPCTDCGALHRHTQTPCSSRDTHCGTCLPGFYEYDKSCVSCPTSTLGSCPEPCVAVCGWRQMFWVQMLVAGLVVPLLLGATLTYTYHRCHPCKAIGPADDTGVEVWTPLQTTHLSPPDSGPALLVTPSSSEKVCPVHLVGHSCTSGSPQTQEAPCLEATWSWDQLPSRAPGLPPPPSPAPPAGSAAATLQPGPQLYDVMDAVPARRWKEFMRTLGLREAEIEAVEVEVGRFRDQQYEMLKRWRQQQHAGLGAVYAALERMGLDGCAEDLRSRLQRGP", "length": 445, "header": "tr|A0A3Q1LIC4-1|E1BHL8_BOVIN Computationally mapped isoform of TNF receptor superfamily member 25 OS=Bos taurus OX=9913 GN=TNFRSF25 PE=4 SV=1 CANONICAL=E1BHL8-1" }, "locus": { "chromosome": "16", "start_pos": 46909144, "end_pos": 46905473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085571.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085571.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058752.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058752.1" } ] } }, { "isoform_ac": "E1BHL8-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL8/entry#E1BHL8-1", "sequence": { "sequence": "MEPRPRPGTSAAAAAAALLFLLLLGARASTPSPRCDCGHSFPKRSGLGCCKGCPAGHYLKAPCTKPCGAATCLPCPQGTFLARENHYETRCARCQACDELAPQMALRNCSAVADTHCGCRPGWFMDCMVSQCRHGSPFRCRPCTDCGALHRHTQTPCSSRDTHCGTCLPGFYEYDKSCVSCPTSTLGSCPEPCVAVCGWRQMFWVQMLVAGLVVPLLLGATLTYTYHRCHPCKAIGPADDTGVEVWTPLQTTHLSPPDSGPALLVTPSSSEKVCPVHLVGHSCTSGSPQTQEAPCLEATWSWDQLPSRAPGLPPPPSPAPPAGSAAATLQPGPQLYDVMDAVPARRWKEFMRTLGLREAEIEAVEVEVGRFRDQQYEMLKRWRQQQHAGLGAVYAALERMGLDGCAEDLRSRLQRGP", "length": 417, "header": "tr|E1BHL8-1|E1BHL8_BOVIN Isoform 1 of TNF receptor superfamily member 25 OS=Bos taurus OX=9913 GN=TNFRSF25 PE=4 SV=2 CANONICAL=E1BHL8-1" }, "locus": { "chromosome": "16", "start_pos": 46909144, "end_pos": 46905103, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008557.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008557.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008557.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008557.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5669034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5669034", "resource": "Reactome", "description": "TNFs bind their physiological receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z929-1", "protein_name": "TNF receptor superfamily member 25", "gene_name": "TNFRSF25", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKRRCPGAASVLLAALWLLASGSQPPGCQDCSMLRSQQGLVLPPNRPRRSTVKSSCPSGMSWIHSAGRCCTQCPPGKFLQTRCTSHGNDSVCVACPAGTFLSHPNTLSKCNACHMCDHQTFQTVVSNCSATSNIACGCESGHFRECQNKDDSCSDFSCKKCNTCPGKLLLQPCSDRQDAQCGSCKPDFYAEGSECRPCHTSNPETCGEECQRVCGHRARGSGLEYILLGLTGPLFLGALAIYHKRKRLQMETLAVSPHPTVPPWDCPDPTACMHPITQRAAATEVVQCQVWEPGPSVARRSSESLALLHQQPSRAALPNGTAEPSVPQEPSTVHSPAPLSSSPQRCALLQGSQLYAVINAVPVRRWKEFMRVLELRDTEIELVEMEVAPFRDRQYEMLKRWCQQTSATLDRIFAALEHMDLSGCAETLRQSLALGP", "length": 436 }, "evidence": [ { "id": "E1BHL8", "url": "https://omabrowser.org/oma/group/E1BHL8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0M411-1", "protein_name": "TNF receptor superfamily member 25", "gene_name": "Tnfrsf25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGLQEWRRCLGGRGRLLGQPQLGQLHVFSSLCSYHRCCCCCYCCLVAMARVVRPAGVTVPVSHRRGQYMKAPCTEPCGDSSCLPCPPGTFLARDSHFKTDCTRCQVCDEEALQVTLENCSAETDTHCGCQSGWCVDCSTEPCGKSSPFSCTPCSSYEPTTYRPCPPGFYIHGNGCASCPTSFSSVCPKACTAVCGWKQMFWVQVLLGASFLLGTVLICAYCRWQPCKPVVTADIAGMETLASPQTTHFSASDSAHTLLPPPGSTGKVCTTVQLVGNNWTPGLSQTEEVVCRQASQPWDQLPNRTLGPPLVPPLSPAPPAGSPAAVLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEICRFRDQQYEMLKRWRQQQPAGLGAIYAALERMGLEGCAEDLRSRLQRGP", "length": 415 }, "evidence": [ { "id": "E1BHL8", "url": "https://omabrowser.org/oma/group/E1BHL8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B1AWN9-1", "protein_name": "Tumor necrosis factor receptor superfamily, member 25", "gene_name": "Tnfrsf25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEARLLRGCVVEPLFLPLLLLLLLLLGGQGQGGMSGRCDCASESQKRYGPFCCRGCPKGHYMKAPCAEPCGNSTCLPCPSDTFLTRDNHFKTDCTRCQVCDEEALQVTLENCSAKSDTHCGCQSGWCVDCSTEPCGKSSPFSCVPCGATTPVHEAPTPRPCLPGFYIRGNDCTSCPTGFSSVCPKACTAVCGWKQMFWVQVLLGVAFLFGAILICAYCRWQPCKAVVTADTAGTETLASPQTAHLSASDSAHTLLAPPSSTGKICTTVQLVGNNWTPGLSQTQEVVCGQASQPWDQLPNRTLGTPLASPLSPAPPAGSPAAVLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEICRFRDQQYEMLKRWRQQQPAGLGAIYAALERMGLEGCAEDLRSRLQRGP", "length": 411 }, "evidence": [ { "id": "E1BHL8", "url": "https://omabrowser.org/oma/group/E1BHL8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q93038-1", "protein_name": "Tumor necrosis factor receptor superfamily member 25", "gene_name": "TNFRSF25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP", "length": 417 }, "evidence": [ { "id": "E1BHL8", "url": "https://omabrowser.org/oma/group/E1BHL8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BHL8", "url": "https://www.uniprot.org/uniprotkb/E1BHL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BHL8", "url": "https://www.uniprot.org/uniprotkb/E1BHL8" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1BHL8", "url": "https://www.uniprot.org/uniprotkb/E1BHL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL8" }, { "id": "PS50017", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Death", "eco_id": "ECO_0000259", "start_pos": 332, "end_pos": 413, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL8" }, { "id": "PS50050", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50050" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TNFR-Cys", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 117, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIA7-1", "uniprot_ac": "E1BIA7", "uniprot_id": "E1BIA7_BOVIN", "mass": { "chemical_mass": 150791.0, "monoisotopic_mass": 150791.0 }, "refseq": { "ac": "XP_024836473", "name": "clustered mitochondria protein homolog isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836473" }, "gene_names": [ { "name": "CLUH", "type": "recommended", "evidence": [ { "id": "E1BIA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA7" } ] }, { "name": "CLUH", "type": "synonym", "evidence": [ { "id": "XP_024836473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836473" } ] } ], "protein_names": [ { "name": "Clustered mitochondria protein homolog", "type": "recommended", "evidence": [ { "id": "E1BIA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA7/entry#names_and_taxonomy" } ] }, { "name": "clustered mitochondria protein homolog isoform X4", "type": "synonym", "evidence": [ { "id": "XP_024836473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836473" } ] } ], "function": [ { "annotation": "mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9RYZ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYZ1#function" }, { "database": "HAMAP", "id": "MF_03013", "url": "https://hamap.expasy.org/signature/MF_03013" }, { "database": "UniProtKB", "id": "A0AAA9SS10", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS10#function" }, { "database": "UniProtKB", "id": "A0A3Q1LJJ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJJ5#function" }, { "database": "UniProtKB", "id": "E1BIA7", "url": "https://www.uniprot.org/uniprotkb/E1BIA7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIA7", "url": "https://www.uniprot.org/uniprotkb/E1BIA7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CLUH", "url": "https://www.uniprot.org/uniprotkb/E1BIA7", "locus": { "chromosome": "19", "start_pos": 23578776, "end_pos": 23608032, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011786", "url": "https://www.ensembl.org/id/ENSBTAG00000011786" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011786", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011786", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15466", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15466", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "531049", "url": "https://www.ncbi.nlm.nih.gov/gene/531049", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LJJ5", "url": "https://www.orthodb.org/?gene=A0A3Q1LJJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BIA7", "url": "https://www.orthodb.org/?gene=E1BIA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12601", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12601", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12601:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12601:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12807", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12807", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024836473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836473", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJJ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYZ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SS10", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SS10-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIA7", "url": "https://www.uniprot.org/uniprotkb/E1BIA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIA7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVIKTDELPAAAPADSAREPSPQAGGKGRPGAAELPSVMLLNGDCPESLKKEEGPAEPPRENGLDETEPGEETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNMLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSLDPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRRMHGDLMYLFVITAEDRQVSITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAALQKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGDVAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIYGSIDFGKTVVSHPRYLELLERTSRPLKILRHRVLNDRDEEVELCSSVECKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEALPEECARAGFPRAHRHKLCCLRQELVDAFVEHRYLLFMKLAALQLMQQKASKMESPTSLENGDGLSSESKPDAPPAPEAGGEEEGSSASGLATVKELAETVASDDGTDPRGREVIRNACKAVGSISSTAFDVRFNPDIFSPGVRFPESCQEEVRDQKQLLKDAAAFLLSCQIPGLVKDFTDHAVLPMDGATLAEVMRQRGINMRYLGKVLDLVMRSPARDQLDHIYKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLPADELISKKRNRRRRNRPPGAADNTAWAVMTPQELWKNICQEAKNYFDFSLECETVDQAVETYGLQKITLLREISLKTGIQILLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLTLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKSLKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRQQLQEASRNRDKAEEPMATEPEPVGASEDAATQPPAAKDPSSPSLQG", "length": 1348, "header": "tr|E1BIA7-1|E1BIA7_BOVIN Isoform 1 of Clustered mitochondria protein homolog OS=Bos taurus OX=9913 GN=CLUH PE=3 SV=4 CANONICAL=E1BIA7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJJ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA7/entry#A0A3Q1LJJ5-1", "sequence": { "sequence": "MAWARVCASCCRQLAEAVLPTPTGVGAEERTPLLGPTPASQSPGPSIWRVPGSPDAGFSCPTNCFISSDPLWGGSGEAGLSPGGSFTRGPEATRASWPTAVLADLEQDARQGECALPRAATAGLAPLKPEANQSSSPGPTSCMGAKVEAQPRTRDTGSAGPEPQSGGLRCHGGPVSPEPRKGRRPTTPELPSVMLLNGDCPESLKKEEGPAEPPRENGLDETEPGEETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNMLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSLDPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRRMHGDLMYLFVITAEDRQVSITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAALQKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGDVAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIYGSIDFGKTVVSHPRYLELLERTSRPLKILRHRVLNDRDEEVELCSSVECKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEALPEECARAGFPRAHRHKLCCLRQELVDAFVEHRYLLFMKLAALQLMQQKASKMESPTSLENGDGLSSESKPDAPPAPEAGGEEEGSSASGLATVKELAETVASDDGTADPRGREVIRNACKAVGSISSTAFDVRFNPDIFSPGVRFPESCQEEVRDQKQLLKDAAAFLLSCQIPGLVKDFTDHAVLPMDGATLAEVMRQRGINMRYLGKVLDLVMRSPARDQLDHIYKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLPADELISKKRNRRRRNRPPGAADNTAWAVMTPQELWKNICQEAKNYFDFSLECETVDQAVETYGLQKITLLREISLKTGIQILLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLTLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKSLKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRQQLQEASRNRDKAEEPMATEPEPVGASEDAATQPPAAKDPSSPSLQG", "length": 1504, "header": "tr|A0A3Q1LJJ5-1|E1BIA7_BOVIN Computationally mapped isoform of Clustered mitochondria protein homolog OS=Bos taurus OX=9913 GN=CLUH PE=3 SV=1 CANONICAL=E1BIA7-1" }, "locus": { "chromosome": "19", "start_pos": 23604183, "end_pos": 23588089, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076822.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076822.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056706.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056706.1" } ] } }, { "isoform_ac": "A0AAA9RYZ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA7/entry#A0AAA9RYZ1-1", "sequence": { "sequence": "MLLNGDCPESLKKEEGPAEPPRENGLDETEPGEETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNMLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSLDPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRRMHGDLMYLFVITAEDRQVSITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAALQKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGDVAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIYGSIDFGKTVVSHPRYLELLERTSRPLKILRHRVLNDRDEEVELCSSVECKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEALPEECARAGFPRAHRHKLCCLRQELVDAFVEHRYLLFMKLAALQLMQQKASKMESPTSLENGDGLSSESKPDAPPAPEAGGEEEGSSASGLATVKELAETVASDDGTADPRGREVIRNACKAVGSISSTAFDVRFNPDIFSPGVRFPESCQEEVRDQKQLLKDAAAFLLSCQIPGLVKDFTDHAVLPMDGATLAEVMRQRGINMRYLGKVLDLVMRSPARDQLDHIYKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLPADELISKKRNRRRRNRPPGAADNTAWAVMTPQELWKNICQEAKNYFDFSLECETVDQAVETYGLQKITLLREISLKTGIQILLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLTLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKSLKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLRARYTWIQLRTIPEIRRSLLRKWRMSGNSTKQQAVALSQQG", "length": 1290, "header": "tr|A0AAA9RYZ1-1|E1BIA7_BOVIN Computationally mapped isoform of Clustered mitochondria protein homolog OS=Bos taurus OX=9913 GN=CLUH PE=3 SV=1 CANONICAL=E1BIA7-1" }, "locus": { "chromosome": "19", "start_pos": 23600383, "end_pos": 23579780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103929.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103929.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074995.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074995.1" } ] } }, { "isoform_ac": "A0AAA9SS10-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA7/entry#A0AAA9SS10-1", "sequence": { "sequence": "MVIKTDELPAAAPADSAREPSPQAGGKGRPGAAELPSVMLLNGDCPESLKKEEGPAEPPRENGLDETEPGEETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNMLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSLDPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRRMHGDLMYLFVITAEDRQVSITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAALQKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGDVAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIYGSIDFGKTVVSHPRYLELLERTSRPLKILRHRVLNDRDEEVELCSSVECKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEALPEECARAGFPRAHRHKLCCLRQELVDAFVEHRYLLFMKLAALQLMQQKASKMESPTSLENGDGLSSESKPDAPPAPEAGGEEEGSSASGLATVKELAETVASDDGTADPRGREVIRNACKAVGSISSTAFDVRFNPDIFSPGVRFPESCQEEVRDQKQLLKDAAAFLLSCQIPGLKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLPADELISKKRNRRRRNRPPGAADNTAWAVMTPQELWKNICQEAKNYFDFSLECETVDQAVETYGLQKITLLREISLKTGIQILLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLTLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKSLKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRQQLQEASRNRDKAEEPMATEPEPVGASEDAATQPPAAKDPSSPSLQG", "length": 1298, "header": "tr|A0AAA9SS10-1|E1BIA7_BOVIN Computationally mapped isoform of Clustered mitochondria protein homolog OS=Bos taurus OX=9913 GN=CLUH PE=3 SV=1 CANONICAL=E1BIA7-1" }, "locus": { "chromosome": "19", "start_pos": 23607833, "end_pos": 23588089, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105715.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105715.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085793.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085793.1" } ] } }, { "isoform_ac": "E1BIA7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA7/entry#E1BIA7-1", "sequence": { "sequence": "MVIKTDELPAAAPADSAREPSPQAGGKGRPGAAELPSVMLLNGDCPESLKKEEGPAEPPRENGLDETEPGEETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNMLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSLDPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRRMHGDLMYLFVITAEDRQVSITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAALQKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGDVAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIYGSIDFGKTVVSHPRYLELLERTSRPLKILRHRVLNDRDEEVELCSSVECKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEALPEECARAGFPRAHRHKLCCLRQELVDAFVEHRYLLFMKLAALQLMQQKASKMESPTSLENGDGLSSESKPDAPPAPEAGGEEEGSSASGLATVKELAETVASDDGTDPRGREVIRNACKAVGSISSTAFDVRFNPDIFSPGVRFPESCQEEVRDQKQLLKDAAAFLLSCQIPGLVKDFTDHAVLPMDGATLAEVMRQRGINMRYLGKVLDLVMRSPARDQLDHIYKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLPADELISKKRNRRRRNRPPGAADNTAWAVMTPQELWKNICQEAKNYFDFSLECETVDQAVETYGLQKITLLREISLKTGIQILLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLTLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKSLKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRQQLQEASRNRDKAEEPMATEPEPVGASEDAATQPPAAKDPSSPSLQG", "length": 1348, "header": "tr|E1BIA7-1|E1BIA7_BOVIN Isoform 1 of Clustered mitochondria protein homolog OS=Bos taurus OX=9913 GN=CLUH PE=3 SV=4 CANONICAL=E1BIA7-1" }, "locus": { "chromosome": "19", "start_pos": 23607833, "end_pos": 23588089, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015643.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015643.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015643.7", "url": "https://www.ensembl.org/id/ENSBTAP00000015643.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BIA7", "url": "https://www.uniprot.org/uniprotkb/E1BIA7" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1BIA7", "url": "https://www.uniprot.org/uniprotkb/E1BIA7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BIA7", "url": "https://www.uniprot.org/uniprotkb/E1BIA7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "E1BIA7", "url": "https://www.uniprot.org/uniprotkb/E1BIA7" } ], "pmid": "" }, { "name": "intracellular distribution of mitochondria", "id": "GO:0048312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048312", "evidence": [ { "database": "UniProtKB", "id": "E1BIA7", "url": "https://www.uniprot.org/uniprotkb/E1BIA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1252, "end_pos": 1254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA7" }, { "id": "PS51823", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51823" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Clu", "eco_id": "ECO_0000259", "start_pos": 373, "end_pos": 615, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1252, "end_pos": 1254 }, { "start_pos": 299, "end_pos": 301 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK80-1", "uniprot_ac": "E1BK80", "uniprot_id": "E1BK80_BOVIN", "mass": { "chemical_mass": 99251.0, "monoisotopic_mass": 99251.0 }, "refseq": {}, "gene_names": [ { "name": "PDE6A", "type": "recommended", "evidence": [ { "id": "E1BK80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ] } ], "protein_names": [ { "name": "Phosphodiesterase", "type": "recommended", "evidence": [ { "id": "E1BK80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK80/entry#names_and_taxonomy" } ] }, { "name": "3.1.4.-", "type": "synonym", "evidence": [ { "id": "E1BK80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK80/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PDE6A", "url": "https://www.uniprot.org/uniprotkb/E1BK80", "locus": { "chromosome": "7", "start_pos": 61195051, "end_pos": 61269840, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012945", "url": "https://www.ensembl.org/id/ENSBTAG00000012945" } ] } } ], "crossref": [ { "id": "E1BK80", "url": "https://alphafold.ebi.ac.uk/entry/E1BK80", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012945", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012945", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00077", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00077", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GPHFTKR", "url": "https://omabrowser.org/oma/group/GPHFTKR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LRJ8", "url": "https://www.orthodb.org/?gene=A0A3Q1LRJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BK80", "url": "https://www.orthodb.org/?gene=E1BK80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00233", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00233", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01590", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01590", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2485179", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2485179", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2514859", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2514859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4086398", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4086398", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LRJ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZ82", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZ82-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK80-1", "url": "https://www.uniprot.org/uniprotkb/E1BK80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEVTAEEVEKFLDSNVSFAKQYYNLRYRAKVISDLLGPREAAVDFSNYHALNSVEESEIIFDLLRDFQDNLQAEKCVFNVMKKLCFLLQADRMSLFMYRARNGIAELATRLFNVHKDAVLEECLVAPDSEIVFPLDMGVVGHVALSKKIVNVPNTEEDEHFCDFVDTLTEYQTKNILASPIMNGKDVVAIIMAVNKVDGPHFTENDEEILLKYLNFANLIMKVFHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAPPYAGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPTYVAQNGLICNIMNAPSEDFFAFQKEPLDESGWVIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLMESLAQFLGWSVLNPDTYELMNKLENRKDIFQDMVKYHVKCDNEEIQTILKTREVYGKEPWECEEEELAEILQGELPDADKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRRITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYETQQEWTQYMMLDQTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYETKMKGLEEEKQKQQAANQAAAGSQHGGKQPGGGPASKSCCVQ", "length": 859, "header": "tr|E1BK80-1|E1BK80_BOVIN Isoform 1 of Phosphodiesterase OS=Bos taurus OX=9913 GN=PDE6A PE=3 SV=3 CANONICAL=E1BK80-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LRJ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BK80/entry#A0A3Q1LRJ8-1", "sequence": { "sequence": "MGEVTAEEVEKFLDSNVSFAKQYYNLRYRAKVISDLLGPREAAVDFSNYHALNSVEESEIIFDLLRDFQDNLQAEKCVFNVMKKLCFLLQADRMSLFMYRARNGIAELATRLFNVHKDAVLEECLVAPDSEIVFPLDMGVVGHVALSKKIVNVPNTEEDEHFCDFVDTLTEYQTKNILASPIMNGKDVVAIIMAVNKVDGPHFTENDEEILLKYLNFANLIMKVFHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAPPYAGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPTYVAQNGLVSNITLKGESFESKEPLDESGWVIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLMESLAQFLGWSVLNPDTYELMNKLENRKDIFQDMVKYHVKCDNEEIQTILKTREVYGKEPWECEEEELAEILQGELPDADKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRRITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYETQQEWTQYMMLDQTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYETKMKGLEEEKQKQQAANQAAAGSQHGGKQPGGGPASKSCCVQ", "length": 856, "header": "tr|A0A3Q1LRJ8-1|E1BK80_BOVIN Computationally mapped isoform of Phosphodiesterase OS=Bos taurus OX=9913 GN=PDE6A PE=3 SV=1 CANONICAL=E1BK80-1" }, "locus": { "chromosome": "7", "start_pos": 61269750, "end_pos": 61195586, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077504.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077504.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062900.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062900.1" } ] } }, { "isoform_ac": "A0AAA9RZ82-1", "url": "https://www.uniprot.org/uniprotkb/E1BK80/entry#A0AAA9RZ82-1", "sequence": { "sequence": "MGEVTAEEVEKFLDSNVSFAKQYYNLRYRAKVISDLLGPREAAVDFSNYHALNSVEESEIIFDLLRDFQDNLQAEKCVFNVMKKLCFLLQADRMSLFMYRARNGIAELATRLFNVHKDAVLEECLVAPDSEIVFPLDMGVVGHVALSKKIVNVPNTEEILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAPPYAGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPTYVAQNGLICNIMNAPSEDFFAFQKEPLDESGWVIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLMESLAQFLGWSVLNPDTYELMNKLENRKDIFQDMVKYHVKCDNEEIQTILKTREVYGKEPWECEEEELAEILQGELPDADKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRRITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYETQQEWTQYMMLDQTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYETKMKGLEEEKQKQQAANQAAAGSQHGGKQPGGGPASKSCCVQ", "length": 778, "header": "tr|A0AAA9RZ82-1|E1BK80_BOVIN Computationally mapped isoform of Phosphodiesterase OS=Bos taurus OX=9913 GN=PDE6A PE=3 SV=1 CANONICAL=E1BK80-1" }, "locus": { "chromosome": "7", "start_pos": 61269750, "end_pos": 61195586, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132124.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132124.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078903.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078903.1" } ] } }, { "isoform_ac": "E1BK80-1", "url": "https://www.uniprot.org/uniprotkb/E1BK80/entry#E1BK80-1", "sequence": { "sequence": "MGEVTAEEVEKFLDSNVSFAKQYYNLRYRAKVISDLLGPREAAVDFSNYHALNSVEESEIIFDLLRDFQDNLQAEKCVFNVMKKLCFLLQADRMSLFMYRARNGIAELATRLFNVHKDAVLEECLVAPDSEIVFPLDMGVVGHVALSKKIVNVPNTEEDEHFCDFVDTLTEYQTKNILASPIMNGKDVVAIIMAVNKVDGPHFTENDEEILLKYLNFANLIMKVFHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAPPYAGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPTYVAQNGLICNIMNAPSEDFFAFQKEPLDESGWVIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLMESLAQFLGWSVLNPDTYELMNKLENRKDIFQDMVKYHVKCDNEEIQTILKTREVYGKEPWECEEEELAEILQGELPDADKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRRITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYETQQEWTQYMMLDQTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYETKMKGLEEEKQKQQAANQAAAGSQHGGKQPGGGPASKSCCVQ", "length": 859, "header": "tr|E1BK80-1|E1BK80_BOVIN Isoform 1 of Phosphodiesterase OS=Bos taurus OX=9913 GN=PDE6A PE=3 SV=3 CANONICAL=E1BK80-1" }, "locus": { "chromosome": "7", "start_pos": 61269750, "end_pos": 61195586, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036662.5", "url": "https://www.ensembl.org/id/ENSBTAT00000036662.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036518.5", "url": "https://www.ensembl.org/id/ENSBTAP00000036518.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-2485179", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2485179", "resource": "Reactome", "description": "Activation of the phototransduction cascade" }, { "id": "R-BTA-2514859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2514859", "resource": "Reactome", "description": "Inactivation, recovery and regulation of the phototransduction cascade" }, { "id": "R-BTA-4086398", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4086398", "resource": "Reactome", "description": "Ca2+ pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z8C9-1", "protein_name": "Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha", "gene_name": "Pde6a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEVTAEEVEKFLDSNIGFAKQYYNFHYRGKVVSDLLGAKEAAVDFSNYHDVNRVEESEIIFDLLRDFQENLQAEKCTFNVMKKLCFLLRADRMSLFMYRTRNGIAELATRLFNVHKDAVLEDCLVMPDSEIVFPLDMGVVGHVAHSKKIANVPNTEEDEHFCDFVDSLTEYQTKSILASPIMNGKDVVAIIMAVNKIDEPHFTKRDEEILLKYLNFVNLIMKVFHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAPAYSGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPADHWALVSGLPTYVAQNGLICNIMNAPAEDFFEFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDDMDETLMESLTQFLGWSVLNPDTYESMNKLENRKDIFQDIVKYHVKCDNEEIQKILKTREVYGKEPWECEEEELAEILQEELPDAEKYEINKFHFSDLPLTELELVKCGIQMYYELRVVDKFHIPQEALVRFMYSLSKGYRRITYHNWRHGFNVGQTMFSLLMTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYESTQEWTQYMMLEQTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYEARMKALEEEKQKQQAAKQAASGNQPGGNPSPGGAPASKSCCIQ", "length": 860 }, "evidence": [ { "id": "E1BK80", "url": "https://omabrowser.org/oma/group/E1BK80/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RL89-1", "protein_name": "Phosphodiesterase", "gene_name": "PDE6A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGEVTAEEVEKFLDSNVGFAKRYFNLRYRPKVISELLGAREAAVDLSHYHPLNSVEESEVVFDLLRDFQENLQAEKCIFNVMKKLSFLLQADRMSLFMHRARNGTAELATRLFNVHKDAVLEDCLVAPDSEIVFPLDMGVVGHVALSKKMVNVPNAQEDEHFCDFVDKLTEYQTKHLLASPIMNGKDVVAVLMAVNKVDGPHFTQRDEEILVKYLNFANIIMKVFHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAPPYSGPRTPDGREISFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPTYVAQNGLICNIMNAPAEDFFAFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDDMDETLMESLAQFLGWSVLNPDTYESMNKLENRKDIFQDMVKYHVKCDNEEIQKILKTRETYGKEPWECEEDELAEILREELPDAEKYEISKFHFSDLPLTELELVKCGIRMYYELRVVDKFHIPQEALVRFMYSLSKGYRRITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYETQQEWTQYMMLEQTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERSVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRREWKALADAYDAKTKAQEEEKQKQPAASQGPRRAEDGELRPGAGSPSPGDAPASKSCSIQ", "length": 866 }, "evidence": [ { "id": "E1BK80", "url": "https://omabrowser.org/oma/group/E1BK80/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P16499-1", "protein_name": "Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha", "gene_name": "PDE6A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEVTAEEVEKFLDSNIGFAKQYYNLHYRAKLISDLLGAKEAAVDFSNYHSPSSMEESEIIFDLLRDFQENLQTEKCIFNVMKKLCFLLQADRMSLFMYRTRNGIAELATRLFNVHKDAVLEDCLVMPDQEIVFPLDMGIVGHVAHSKKIANVPNTEEDEHFCDFVDILTEYKTKNILASPIMNGKDVVAIIMAVNKVDGSHFTKRDEEILLKYLNFANLIMKVYHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEVPPYSGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPAYVAQNGLICNIMNAPAEDFFAFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLMESLTQFLGWSVLNPDTYESMNKLENRKDIFQDIVKYHVKCDNEEIQKILKTREVYGKEPWECEEEELAEILQAELPDADKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRKITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYESEQEWTQYMMLEQTRKEIVMAMMMTACDLSAITKPWEVQSQVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYDAKMKVQEEKKQKQQSAKSAAAGNQPGGNPSPGGATTSKSCCIQ", "length": 860 }, "evidence": [ { "id": "E1BK80", "url": "https://omabrowser.org/oma/group/E1BK80/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q800E7-1", "protein_name": "Phosphodiesterase", "gene_name": "pde6a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAVDKDVAEKFLDSNPMFAKQYYDSRFRAKVVSDLLSTTKQTAVDISSHHELSSMEECEIIFDMVRDMQENLHMERAVFNLMRHLSFMIRADRMSLFMYRQRNGIAELATRIFNVHKDATLEECLVPPDSEIVYPLDTGIVGHVATAKKTVNVPDVTKDSHFSDFVDNLTEYETKNVLATPIMNGKDMVAVMMAVNKIGAPHFTAQDEETLKKYLNFANLVLRVFHLSYLHNCETRRGQVLLWSASKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKTKEFFDLWPVLMGEVPPYSGPKTPDGREVIFYKVIDYILHGKEDIKVIPNPPADHWALVSGLPTYVAENGLICNIMNAAQDEFFEFQKEPLDESGWMIKNVLSLPIVNKKEEIVGVATFYNRKDGKPFDEMDETLMESLTQFLGWSVLNTDTYDKMNKLENRKDIFQDMVMYHVKCRKDEIQNILNTREMYDKEPDECEEDELEDILNEVLPDSEESEIFEFHFCDFEFSELDLVKCGIKMYYELGVVDKFHIPRETLVRFVYSVSKGYRKITYHNWRHGFNVGQTMFTLLMTGDLKRYYTDLEAMAMVTAGLCHDIDHRGTNNLYQMKSGNPLAKLHGSSILERHHLEFGKTLLRDEALNIYQNLNRRQHETVIHLMDIAIIATDLALYFKKRTMFQKIVDQSKTYDSWDSWTKYMMLETTRKEIVMAMMMTACDLSAIAKPWEIQSKVALSVAAEFWEQGDLERTVLEQQPIPMMDRNKAEELPKLQCGFIDFVCSFVYKEFSRFHVEITPMLERLLNNRKEWNALKEIHEAKVAKLDEAKKAKEEAHANSDHKQGNSVQPAAQSKTCVIS", "length": 858 }, "evidence": [ { "id": "E1BK80", "url": "https://omabrowser.org/oma/group/E1BK80/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ], "pmid": "" }, { "name": "negative regulation of cAMP/PKA signal transduction", "id": "GO:0141162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141162", "evidence": [ { "database": "UniProtKB", "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ], "pmid": "" }, { "name": "3',5'-cyclic-nucleotide phosphodiesterase activity", "id": "GO:0004114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004114", "evidence": [ { "database": "UniProtKB", "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ], "pmid": "" }, { "name": "3',5'-cyclic-GMP phosphodiesterase activity", "id": "GO:0047555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047555", "evidence": [ { "database": "UniProtKB", "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ], "pmid": "" }, { "name": "3',5'-cyclic-AMP phosphodiesterase activity", "id": "GO:0004115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004115", "evidence": [ { "database": "UniProtKB", "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "photoreceptor disc membrane", "id": "GO:0097381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097381", "evidence": [ { "database": "UniProtKB", "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ], "pmid": "" }, { "name": "photoreceptor outer segment membrane", "id": "GO:0042622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042622", "evidence": [ { "database": "UniProtKB", "id": "E1BK80", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-2584246", "name": "GNAT1-GTP hydrolyses its bound GTP to GDP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, photoreceptor disc membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P04695-1", "F1N0U0-1", "E1BK80-1" ], "evidence": [ { "id": "R-BTA-2584246", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2584246" } ] }, { "id": "R-BTA-4086392", "name": "PDE6 hydrolyses cGMP to GMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-30991" ], "output_participant_list": [], "enzyme_list": [ "F1N0U0-1", "E1BK80-1" ], "evidence": [ { "id": "R-BTA-4086392", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4086392" } ] }, { "id": "R-BTA-74059", "name": "PDE6 hydrolyses cGMP to GMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, photoreceptor disc membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P04695-1", "F1N0U0-1", "E1BK80-1" ], "evidence": [ { "id": "R-BTA-74059", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-74059" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-30991", "participant_name": "cGMP [cytosol]", "crossref": [ { "id": "57746", "database": "ChEBI", "url": "" }, { "id": "ZINC000004095501", "database": "ZINC", "url": "" }, { "id": "C00942", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BK80", "gene_name": "PDE6A", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "E1BK80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK80" } ] } ] }, { "uniprot_ac": "F1N0U0", "gene_name": "PDE6B", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "F1N0U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0U0" } ] } ] }, { "uniprot_ac": "P04695", "gene_name": "GNAT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P04695", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04695" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BK80-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 859, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BK80-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BK80" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BK80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK80" }, { "id": "PS51845", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51845" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "66324", "url": "https://www.rhea-db.org/rhea/66324", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "66328", "url": "https://www.rhea-db.org/rhea/66328", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LZF9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDX2", "url": "https://www.uniprot.org/uniprotkb/E1BDX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDX2-1", "url": "https://www.uniprot.org/uniprotkb/E1BDX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MITLTELKCLADAQSCYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASVNASSDAGMPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLTLSKSKVLLSSSGCSAGDVDSNKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRLHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTYITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKVELHLFMLNGLPDNVFELTEIEVLSLELIPEVKLPSAISQLVSLKELHVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQVSTMQLEGFQDLKNLRTLYLKSSLSRIPQVITDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMSLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRSCLIVEENLLNTLPPPVTERLQTCLDKC", "length": 804, "header": "tr|E1BDX2-1|E1BDX2_BOVIN Isoform 1 of Leucine rich repeat containing 8 VRAC subunit B OS=Bos taurus OX=9913 GN=LRRC8B PE=3 SV=1 CANONICAL=E1BDX2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LZF9-1", "url": "https://www.uniprot.org/uniprotkb/E1BDX2/entry#A0A3Q1LZF9-1", "sequence": { "sequence": "MITLTELKCLADAQSCYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASVNASSDAGMPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLTLSKSKVLLSSSGCSAGDVDSNKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRLHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTYITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKVELHLFMLNGLPDNVFELTEIEVLSLELIPEVKLPSAISQLVSLKELHVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQVSTMQLEGFQDLKNLRTLYLKSSLSRIPQVITDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMSLSPHVGELSNLTHLELIGIVMPFQTMK", "length": 767, "header": "tr|A0A3Q1LZF9-1|E1BDX2_BOVIN Computationally mapped isoform of Leucine rich repeat containing 8 VRAC subunit B OS=Bos taurus OX=9913 GN=LRRC8B PE=3 SV=1 CANONICAL=E1BDX2-1" }, "locus": { "chromosome": "3", "start_pos": 53700159, "end_pos": 53688976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069929.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069929.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061087.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061087.1" } ] } }, { "isoform_ac": "E1BDX2-1", "url": "https://www.uniprot.org/uniprotkb/E1BDX2/entry#E1BDX2-1", "sequence": { "sequence": "MITLTELKCLADAQSCYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASVNASSDAGMPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLTLSKSKVLLSSSGCSAGDVDSNKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRLHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTYITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKVELHLFMLNGLPDNVFELTEIEVLSLELIPEVKLPSAISQLVSLKELHVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQVSTMQLEGFQDLKNLRTLYLKSSLSRIPQVITDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMSLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRSCLIVEENLLNTLPPPVTERLQTCLDKC", "length": 804, "header": "tr|E1BDX2-1|E1BDX2_BOVIN Isoform 1 of Leucine rich repeat containing 8 VRAC subunit B OS=Bos taurus OX=9913 GN=LRRC8B PE=3 SV=1 CANONICAL=E1BDX2-1" }, "locus": { "chromosome": "3", "start_pos": 53700159, "end_pos": 53690416, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026919.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026919.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026919.4", "url": "https://www.ensembl.org/id/ENSBTAP00000026919.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:517584", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517584", "resource": "KEGG Pathway" }, { "id": "R-BTA-5223345", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5223345", "resource": "Reactome", "description": "Miscellaneous transport and binding events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7H9C0-1", "protein_name": "Volume-regulated anion channel subunit LRRC8B", "gene_name": "Lrrc8b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MITLTELKYLADAQSTYHILKPWWDVFWYYITLVMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDLLKASRNMSSNTAMPLPLPLRIQNDLHRQQYSYIDAVCYERQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILQKCFDSPWTTRALSETVAEQSVRPLKPSKSKTLLSTSCSADTDANKQALPYPQPGLESPGIESPTSSVLDKKEGEQAKAIFEKVKRFRLHVEQRDIIYRVYLRQIIVKVIFFVLIITYVPYFLSYITLEIDCLIDVQAFTGYKRYQCVYTLAEIFKVLASFYVVLVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVRNSQDKVELHLFMLSGLPDNIFELTEVEVLSLELIPEVKLPASISQLVNLKELHVYHSSLVVDHPALAFLEGNLKTLRLKFTEMGKIPRWVFYLKNLKELYLSGCVLPEQLGTTQMEGFQDLKNLTTLYLKSNLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMINLKSLELLSCDLERIPHSIFSLNNLHELDLKENNLKTVEEIISFQHLPSLSCLKLWHNNIAYIPAQIGTLSNLEQLFLSHNNIESLPLQLFLCTKLHYLDLSDNHLTFIPDEIQYLTNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLTYLSPLVGELSNLTHLELTGNYLETLPPELEGCQALKRSCLIVEDSLLNTLPLPVTERLQTCLDKC", "length": 802 }, "evidence": [ { "id": "E1BDX2", "url": "https://omabrowser.org/oma/group/E1BDX2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A758-1", "protein_name": "Leucine rich repeat containing 8 VRAC subunit B", "gene_name": "Lrrc8b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITLTELKCLADAQSSYHILKPWWDVFWYYLTLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDLLKASENTSSNSGLPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVSILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKTLLSTSGGSADIDASKQSLPYPQPGLESPGIESPTSSVLDKKEGEQAKAIFEKVKRFRLHVEQRDIIYRVYLKQIIVKVILFVLIITYVPYFLSYITLEIDCSIDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVMLYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNSQDKVELHLFMLNGLPDNVFELTDMEVLSLELIPEVKLPAAASQLVNLRELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSSMQPEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELLSCDLERIPHSIFSLNNLHELDLKENNLKTVEEIISFQHLPSLSCLKLWHNNIAYIPAQIGALSNLEQLYLGHNNIESLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLTNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGRNSLTDLSPLVGELSNLTHLELIGNYLETLPVELEGCQSLKRSCLIVEDSLLNSLPLPVTERLQTCLDKC", "length": 803 }, "evidence": [ { "id": "E1BDX2", "url": "https://omabrowser.org/oma/group/E1BDX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BZK2-1", "protein_name": "Leucine rich repeat containing 8 VRAC subunit B", "gene_name": "LOC107056693", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MITLTELKYLADAQSSYHILKPWWDVFWYYLTMIMLLVAVLAGALQLTQTRVLCCLPCKLEFDNHCAVPWDLIKTNLNMSASSTAQIIIPLKIQNDLHRQQYSYIDAVCYERQLHWFAKFFPYLVLLHTFIFAACSNFWLYYPSTSSRLEHFVAILQKCFDSPWTTRALSETVAEQSVRKLPVAKSKAVISSPGSSVDVGASRQSLPYTQPGLETTGRENSSVLDKKEGEQAKAIFEKVKKFRVHVEEKDVIYRVYMKQIIVKVIVFVIIIIYVPYYLSFIKLEIDCIVNVQAFTGYKRYQCVYSLAEIFKVLASFYVVLVIFYGLTCTYSLWWMLRSSLKQYSFEKLREKSNYSDIPDVKNDFAFILHLADQYDPLYSQRFSIFLSDLSENKLKQINLNNEWSVEKLKNKLIRNSQDKVELHLFMLSGLPDSVFELTEIEVLSLELIPEAKLPSAVTQLVNLKDLNVYHSSITMDYPAVSFLEENLKTLRLKSSEMGRIPFWVFHLKNLKELCLTGYFMLDHQNSIYNESFQGLKNLRSIHLKNNLSRIPQVVTDLPSLQHLSINNEGNKLIVLNNLKKLVNLRTLELICCDLERIPHSIFTLNNLHEIDLRENNLRTVEEIISFQHLKNLSCLKLWHNSISYVPVQIGALSNLEQLYLNYNNIKDVPLQLFLCKKLQYLDLSYNKLTSIPEEIGYLTNLQYLALTKNHIEMLPDRLFQCKKLQFLLLGNNSLMNLSPLVGQLLNLVHLELTGNYLESLPAELEECQFLKRNSLIVEERLLKTLPPRVRDRLQTSSDKC", "length": 800 }, "evidence": [ { "id": "E1BDX2", "url": "https://omabrowser.org/oma/group/E1BDX2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5DU41-1", "protein_name": "Volume-regulated anion channel subunit LRRC8B", "gene_name": "Lrrc8b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNQCAVPWDLLKGSENASSNSGLLLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVSILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKTLLSTSGGSADIDASKQSLPYPQPGLESPGIESPTSSVLDKKEGEQAKAIFEKVKRFRLHVEQRDIIYRVYLKQIIVKVILFVLIITYVPYFLSYITLEIDCSIDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVMLYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVERLKSKLVKNSQDKVELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPAAVAQLVNLRELHVYHSSLVVDHPALAFLEENLRILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSSLHLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELLSCDLERIPHSIFSLNNLHELDLKENNLKTVEEIISFQHLPSLSCLKLWHNNIAYIPAQIGALSNLEQLFLGHNNIESLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLTNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGRNSLTDLSPLVGELSNLTHLELTGNYLETLPVELEGCQSLKRSCLIVEDSLLNSLPLPVAERLQTCLDKC", "length": 803 }, "evidence": [ { "id": "E1BDX2", "url": "https://omabrowser.org/oma/group/E1BDX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6P9F7-1", "protein_name": "Volume-regulated anion channel subunit LRRC8B", "gene_name": "LRRC8B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC", "length": 803 }, "evidence": [ { "id": "E1BDX2", "url": "https://omabrowser.org/oma/group/E1BDX2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BDX2", "url": "https://www.uniprot.org/uniprotkb/E1BDX2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BDX2", "url": "https://www.uniprot.org/uniprotkb/E1BDX2" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "E1BDX2", "url": "https://www.uniprot.org/uniprotkb/E1BDX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "E1BDX2", "url": "https://www.uniprot.org/uniprotkb/E1BDX2" } ], "pmid": "" }, { "name": "monoatomic anion transmembrane transport", "id": "GO:0098656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098656", "evidence": [ { "database": "UniProtKB", "id": "E1BDX2", "url": "https://www.uniprot.org/uniprotkb/E1BDX2" } ], "pmid": "" }, { "name": "aspartate transmembrane transport", "id": "GO:0015810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015810", "evidence": [ { "database": "UniProtKB", "id": "E1BDX2", "url": "https://www.uniprot.org/uniprotkb/E1BDX2" } ], "pmid": "" }, { "name": "cyclic-GMP-AMP transmembrane import across plasma membrane", "id": "GO:0140361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140361", "evidence": [ { "database": "UniProtKB", "id": "E1BDX2", "url": "https://www.uniprot.org/uniprotkb/E1BDX2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "volume-sensitive anion channel activity", "id": "GO:0005225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005225", "evidence": [ { "database": "UniProtKB", "id": "E1BDX2", "url": "https://www.uniprot.org/uniprotkb/E1BDX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 750, "end_pos": 752, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29823", "name": "", "equation": "chloride(in) = chloride(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MN01-1", "Q5E9B7-1", "Q9XSA7-1", "P35071-1", "P35526-1" ], "evidence": [ { "id": "29823", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29823" } ] }, { "id": "66324", "name": "", "equation": "iodide(out) = iodide(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5E9B7-1", "Q9XSA7-1" ], "evidence": [ { "id": "66324", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66324" } ] }, { "id": "66328", "name": "", "equation": "taurine(out) = taurine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "66328", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66328" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] }, { "uniprot_ac": "Q5E9B7", "gene_name": "CLIC1", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "Q5E9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B7" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "Q5E9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B7" } ] } ] }, { "uniprot_ac": "Q9XSA7", "gene_name": "CLIC4", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "Q9XSA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XSA7" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDX2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 804, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDX2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDX2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 356, "end_pos": 358 }, { "start_pos": 635, "end_pos": 637 }, { "start_pos": 750, "end_pos": 752 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDR3-1", "uniprot_ac": "E1BDR3", "uniprot_id": "E1BDR3_BOVIN", "mass": { "chemical_mass": 74722.0, "monoisotopic_mass": 74722.0 }, "refseq": { "ac": "XP_002688491", "name": "sulfate anion transporter 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688491" }, "gene_names": [ { "name": "SLC26A1", "type": "recommended", "evidence": [ { "id": "E1BDR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ] }, { "name": "SLC26A1", "type": "synonym", "evidence": [ { "id": "XP_002688491", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688491" } ] } ], "protein_names": [ { "name": "Solute carrier family 26 member 1", "type": "synonym", "evidence": [ { "id": "E1BDR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDR3/entry#names_and_taxonomy" } ] }, { "name": "sulfate anion transporter 1", "type": "synonym", "evidence": [ { "id": "XP_002688491", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688491" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC26A1", "url": "https://www.uniprot.org/uniprotkb/E1BDR3", "locus": { "chromosome": "6", "start_pos": 117387602, "end_pos": 117377049, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007001", "url": "https://www.ensembl.org/id/ENSBTAG00000007001" } ] } } ], "crossref": [ { "id": "E1BDR3", "url": "https://alphafold.ebi.ac.uk/entry/E1BDR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007001", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007001", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100140312", "url": "https://www.ncbi.nlm.nih.gov/gene/100140312", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036513", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036513", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100140312", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140312", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNENQDL", "url": "https://omabrowser.org/oma/group/WNENQDL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M3P2", "url": "https://www.orthodb.org/?gene=A0A3Q1M3P2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BDR3", "url": "https://www.orthodb.org/?gene=E1BDR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11814", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11814", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01740", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01740", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-174362", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174362", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-427601", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-427601", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002688491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688491", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3P2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDR3-1", "url": "https://www.uniprot.org/uniprotkb/E1BDR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEASPEYTEWGGQLVLVRWRPPPPPGLGEVLKAGLRRSCACSLQGTWAQLQALFPAVHWLRQYRPREALVGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELLLAGFDPAQDGLGPGANRSSLNGSAAALVLGLQDCARDCYAIRVATALTLVAGLYQVLMGILGLGFVSAYLSQPLLDGFAMGASVTILTSQLRHLLGVRVPRHQGPGLVVSTWLSLLRSAGQANLCDVLTSAVCLAVLLAAKELSDRFRHRLRVPLPAELLVIVVATIVSHLGQFHERFGSSVAGDIPTGFMAPRVPDAGLMWRVALDAASLALVGSAFSISLAEMFARSHGYAVRANQELLAVGCCNVLPAFFHCFATSAALAKSLVKTATGCHTQLSSVVSAAVVLMVLLVLAPLFRDLQRSVLACVILVSLRGALRKVRDVPRLWRLSPADALVWVATAATCVLVSTEAGLLAGVLFSLLSLAGRTRHPRTALLARAGGSSFYGDPAEFEGLAPEPGVQVFRFTGPLYYANKDFFLQSLYSLTGLDVGYAIARRKERGPGEGAGEGDPVGGRDPGSGSGGASLVPAVTRFHAVVIDCAPLLFLDVAGLATLQELHRDYGALGISLLLACCNPSVTDTLRRGGFLGEDQGDVAEDGQLFPSVHCAVQAARARHQELAASNSIL", "length": 706, "header": "tr|E1BDR3-1|E1BDR3_BOVIN Isoform 1 of Solute carrier family 26 member 1 OS=Bos taurus OX=9913 GN=SLC26A1 PE=4 SV=3 CANONICAL=E1BDR3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M3P2-1", "url": "https://www.uniprot.org/uniprotkb/E1BDR3/entry#A0A3Q1M3P2-1", "sequence": { "sequence": "MYLLARRETRFLHSNTCCLSSKLVKRPEGLPISSKPAATRVASHRSPAWCSQAGTEAAPSGQPGGPRRTRPRRDGEASGTRAMWQLTWDELVLPEKVQVPIQAASGTAPSPPPPLCPSACAARTRRAARRFSQGAHCPTMEASPEYTEWGGQLVLVRWRPPPPPGLGEVLKAGLRRSCACSLQGTWAQLQALFPAVHWLRQYRPREALVGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELLLAGFDPAQDGLGPGANRSSLNGSAAALVLGLQDCARDCYAIRVATALTLVAGLYQVLMGILGLGFVSAYLSQPLLDGFAMGASVTILTSQLRHLLGVRVPRHQGPGLVVSTWLSLLRSAGQANLCDVLTSAVCLAVLLAAKELSDRFRHRLRVPLPAELLVIVVATIVSHLGQFHERFGSSVAGDIPTGFMAPRVPDAGLMWRVALDAASLALVGSAFSISLAEMFARSHGYAVRANQELLAVGCCNVLPAFFHCFATSAALAKSLVKTATGCHTQLSSVVSAAVVLMVLLVLAPLFRDLQRSVLACVILVSLRGALRKVRDVPRLWRLSPADALVWVATAATCVLVSTEAGLLAGVLFSLLSLAGRTRHPRTALLARAGGSSFYGDPAEFEGLAPEPGVQVFRFTGPLYYANKDFFLQSLYSLTGLDVGYAIARRKERGPGEGAGEGDPVGGRDPGSGSGGASLVPAVTRFHAVVIDCAPLLFLDVAGLATLQELHRDYGALGISLLLACCNPSVTDTLRRGGFLGEDQGDVAEDGQLFPSVHCAVQAARARHQELAASNSIL", "length": 845, "header": "tr|A0A3Q1M3P2-1|E1BDR3_BOVIN Computationally mapped isoform of Solute carrier family 26 member 1 OS=Bos taurus OX=9913 GN=SLC26A1 PE=4 SV=2 CANONICAL=E1BDR3-1" }, "locus": { "chromosome": "6", "start_pos": 117386598, "end_pos": 117377248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074945.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074945.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068144.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068144.2" } ] } }, { "isoform_ac": "E1BDR3-1", "url": "https://www.uniprot.org/uniprotkb/E1BDR3/entry#E1BDR3-1", "sequence": { "sequence": "MEASPEYTEWGGQLVLVRWRPPPPPGLGEVLKAGLRRSCACSLQGTWAQLQALFPAVHWLRQYRPREALVGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELLLAGFDPAQDGLGPGANRSSLNGSAAALVLGLQDCARDCYAIRVATALTLVAGLYQVLMGILGLGFVSAYLSQPLLDGFAMGASVTILTSQLRHLLGVRVPRHQGPGLVVSTWLSLLRSAGQANLCDVLTSAVCLAVLLAAKELSDRFRHRLRVPLPAELLVIVVATIVSHLGQFHERFGSSVAGDIPTGFMAPRVPDAGLMWRVALDAASLALVGSAFSISLAEMFARSHGYAVRANQELLAVGCCNVLPAFFHCFATSAALAKSLVKTATGCHTQLSSVVSAAVVLMVLLVLAPLFRDLQRSVLACVILVSLRGALRKVRDVPRLWRLSPADALVWVATAATCVLVSTEAGLLAGVLFSLLSLAGRTRHPRTALLARAGGSSFYGDPAEFEGLAPEPGVQVFRFTGPLYYANKDFFLQSLYSLTGLDVGYAIARRKERGPGEGAGEGDPVGGRDPGSGSGGASLVPAVTRFHAVVIDCAPLLFLDVAGLATLQELHRDYGALGISLLLACCNPSVTDTLRRGGFLGEDQGDVAEDGQLFPSVHCAVQAARARHQELAASNSIL", "length": 706, "header": "tr|E1BDR3-1|E1BDR3_BOVIN Isoform 1 of Solute carrier family 26 member 1 OS=Bos taurus OX=9913 GN=SLC26A1 PE=4 SV=3 CANONICAL=E1BDR3-1" }, "locus": { "chromosome": "6", "start_pos": 117386598, "end_pos": 117384057, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009210.5", "url": "https://www.ensembl.org/id/ENSBTAT00000009210.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009210.4", "url": "https://www.ensembl.org/id/ENSBTAP00000009210.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100140312", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140312", "resource": "KEGG Pathway" }, { "id": "R-BTA-174362", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174362", "resource": "Reactome", "description": "Transport and metabolism of PAPS" }, { "id": "R-BTA-427601", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-427601", "resource": "Reactome", "description": "Inorganic anion exchange by SLC26 transporters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ATM3-1", "protein_name": "Solute carrier family 26 member 1", "gene_name": "SLC26A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEESPECAPQGRGPVLVRRRPPERPGLREALKARLRRGCTCSVQGAWALLQGLFPAMHWLRRYRAREDLAGDVMSGLLIGIILVPQAIAYSLLAGLQPVYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELLQAGFDPAQDGPGPEANSSAPNASATTLALGLQDCGRDCYAIRVATALTLVAGIYQVLMGILRLGFVSAYLSQPLLDGFAMGASVTILTSQLRHLLGVQVPRHQGPGLVISTWLSLLRGAGQANLCDLLTSAVCLTVLLAAKELSDRCRHRLKVPLPAELLVIVVATLASHFGRFHQRFGSSVAGDIPTGFVAPRVPDLGLMWRVAPDAVSLALVGSAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFFHCFATSAALAKSLVKTATGCRTQVSSVVSAAVVLLVLLALAPLFRDLQRSVLACIIVVSLRGALRKVRDVPRLWRLSPADALVWVATAATCVLLSTEAGLLAGVLLSLLSLAGRTQRPRAALLARVADSSFYEDTAEFEGLVPEPGVQVFRFAGPLYYANKDFFLQSLYRLTGLDAGRAASRGRERGPGGQGGRGEPVESRDLGPVSSAAALVPTATCFHAVVVDCAPLLFLDATGLATLQDLRRDYGALGISLLLACCSPSVTDTLRRGGFLGEEPGDAAEEGQLFHSVHSAVLAARACHGEPAATDSTL", "length": 706 }, "evidence": [ { "id": "E1BDR3", "url": "https://omabrowser.org/oma/group/E1BDR3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M3ATV7-1", "protein_name": "Sulfate transporter", "gene_name": "slc26a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGASSLEAMEEDLNCVAVGLLKRRVRQKRGVREIIKTKIQRNLSCTGPKIKSTLTGFFPVVKWLPKYKVKEYIWGDVMSGLIIGIILIPQAIAYCLLAGLEPIYGLYTSFFSNIIYFFMGTSRHVSVGIFSLMSLMVGQVVDREVFLAGFDLNEDSTKNAFGFNDTGETNITAVNLKIMSLNMECGKECYAISIATALTFLAGVYQVLMAFLRLGFVSVYLSSPMLDGFATGASCTILSVQAKYLLGLKIPRHQGYGTVVVTWINIFKNIHKTNFCDLITSAICIIVLLAGKEIQDRYKKILKIPLPTELVVVAVATIVSHFADLNGQFSSSISGAIPTGFIPPKMPSIELMPRIAWDAIPLAVISFAFTVSLSEMFAKKHGYTVRPNQEMIAIGFCNIIPSFFHSFTTSAALAKTMVKDSAGCQTQVSSIVSALVVLLVLLFFAPFFYALQKCVLACIIIVSLRGALRKFRDVPKQWRQSKIEAIVWLVTMSSTALISVELGLVIGVIFSMICVVVQTQNPKVSLLGQIEQTNDYEDMEEYDNLSPVPNVKIFRFQAPLFYANKDFFLKSLYKATKLEPFLELTRRRKLEKKARAKGQKMTDGVDQTNGDVGICLISKDVGFHTIILDCSCISMIDTTAVSTFKTVSKDYKEVGVNVILACCNTTVIDSLRKGSFFGADDIDMDRLLFHTIHSAVCFANSTTQPVNDSSV", "length": 711 }, "evidence": [ { "id": "E1BDR3", "url": "https://omabrowser.org/oma/group/E1BDR3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0YKK9-1", "protein_name": "Sulfate transporter", "gene_name": "SLC26A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKRLYADRINKREQRLCKLTEKPLFNSSSGTAFSKESCAPEELCYCALIRNLLWIYCSCFVPLEKIHEVKARTMERPLEATKMENSTSCFFMERKAHVKARRKEIVLAKLRKSFSCTPRKLKNFVMDFLPVLRWLPKYQCKEYIWGDVMSGLVIGIILVPQAIAYSLLAGLKPIYSLYTSFFANIIYFLMGTSRHVSVGIFSLISLMVGQVVDRELLLAGFDLNDDVTPALGPGSLQTDSQFNTTVFNLTTEGMNAECGKECYAIGIATALTFVAGVYQVLMGVFRLGFVSMYLSESVLDGFATGASLTILTAQVKYLIGIKIPRSQGHGMLVITWINIFRNISQANICDIITSSICIVVLVTAKELGDRYKHKLKFPLPTELVVIVVATLVSHYGNLNEVYSSSVSGAIPTGFIAPKVPRFDLMIRVAIDALPLAVVSFVFTVSLSEMCAKKYAYTIRANQEMFAVGFCNIIPSFFHSFATSAALAKTLVKTSTGCQTQVSGVISAMVVLLVLLFLAPLFYSLQKCVLACIIIVSLRGALRKFRDVPARYHVNKVDTVVWVVTMFASALISTEIGLLVGIVFSMLCIIVRTQQPRTALLGQIPDTNFYEDDLEYENLSSVPKVKIFRFEAPLYYANRNYFLKSLYRLTDLDPNLEAARRKKYEKKERQQLKEGNQPTVNGLGSRDTTLQLVPKQIDFQALIVDCSSIPFLDTTGVNTLKEILKDYKELNISVLLACCNPSVIDSLKRGGYFGKDFGSMQEMLFYSIHNAVRFAKDQKLTADSSV", "length": 785 }, "evidence": [ { "id": "E1BDR3", "url": "https://omabrowser.org/oma/group/E1BDR3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P45380-1", "protein_name": "Sulfate anion transporter 1", "gene_name": "Slc26a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDASPEPPQKGGTLVLVRRQPPVSQGLLETLKARLKKSCTCSMPCAQALVQGLFPVIRWLPQYRLKEYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVNVGIFSLLCLMVGQVVDRELQLAGFDPSQDSLGPGNNDSTLNNTATLTVGLQDCGRDCHAIRIATALTLMAGLYQVLMGILRLGFVSTYLSQPLLDGFAMGASVTILTSQAKHLLGVRIPRHQGLGMVIHTWLSLLQNVGQANLCDVVTSAVCLAVLLTAKELSDRYRHYLKVPVPTELLVIVVATIASHFGQLHTRFGSSVAGNIPTGFVAPQIPDPKIMWSVALDAMSLALVGSAFSISLAEMFARSHGYSVSANQELLAVGCCNVLPAFFHCFATSAALSKTLVKIATGCQTQLSSVVSAAVVLLVLLVLAPLFHDLQRCVLACIIVVSLRGALRKVKDLPQLWRLSPADALVWVATAATCVLVSIEAGLLAGVFFSLLSLAGRTQRPRAALLARIGDSTFYEDAAEFEGLLPPPEVRVFRFTGPLYYANKDFFLRSLYSLTGLDAGYSATRKDRGTEVGVSNRSLVDRKDLGSVSSGDGLVVPLAFGFHTVVIDCAPLLFLDVAGMATLKDLRKNYRALDITLLLACCSPSVRDTLRKGGFLGEDQGTAEELLFPSVHSAVETACARREELMAADSAL", "length": 703 }, "evidence": [ { "id": "E1BDR3", "url": "https://omabrowser.org/oma/group/E1BDR3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P58735-1", "protein_name": "Sulfate anion transporter 1", "gene_name": "Slc26a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDASPEPQQKGGTLVLVRRQPPVSQGLLETLKARLKKSCTCSMPCAQALVQGLFPAIHWLPQYRLKEYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVNVGIFSLLCLMVGQVVDRELQLAGFDPSQDSLGPKNNDSTLNNSATTLIIGLQDCRRDCYAIRVATALTLMAGLYQVLMGILRLGFVSTYLSQPLLDGFAMGASVTILTSQAKHMLGVQIPRHQGLGMVVHTWLSLLQNVGQANICDVVTSALCLGVLLAAKELSDRYRHRLKVPIPTELFVIVVATIVSHFGQLHTRFDSRVAGNIPTGFVAPQVPDPKIMWRVALDAMSLALVGSAFSISLAEMFARSHGYSVSANQELLAVGCCNVLPAFFHCFATSAALSKTLVKIATGCQTQLSSVVSAAVVLLVLLVLAPLFHDLQRCVLACIIVVSLRGALRKVKDLPQLWRLSPADALVWVATAATCVLVSTEAGLLAGVFFSLLSLAGRTQRPRAALLARIGDSTFYEDAAEFEGLLPPPEVRVFRFTGPLYYANKDFFLRSLYRLTGLDAGHSATRKDQGPEVGVSNRSLVDGKDLGSVSSGAGLVVPLAFGFHTVVIDCAPLLFLDVAGMATLKDLRRDYRALDITLLLACCSPSVRDTLRKGGFLGEEQGAENELLFPSVHSAVEAACARREELLAADSAL", "length": 704 }, "evidence": [ { "id": "E1BDR3", "url": "https://omabrowser.org/oma/group/E1BDR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2B4-1", "protein_name": "Sulfate anion transporter 1", "gene_name": "SLC26A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARARHRELEATDAHL", "length": 701 }, "evidence": [ { "id": "E1BDR3", "url": "https://omabrowser.org/oma/group/E1BDR3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LW86-1", "protein_name": "Probable sulfate transporter 3.4", "gene_name": "SULTR3;4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGHGTNRVEDMASPNNGTAGETVVEIHSVCLPPKKTAFQKLKKRVGDVFFPDDPLQRFRNQTWRNRVILGLQSLFPIFTWGSQYDLKLLRSDVISGLTIASLAIPQGISYAKLANLPPIVGLYSSFVPPLIYAVLGSSRHLAVGPVSIASLVMGSMLSESVSPTQDSILYLKLAFTSTFFAGVFQASLGLLRLGFMIDFLSKATLIGFTAGAAVIVSLQQLKGLLGIVHFTGKMQIVPVMSSVFNHRSEWSWETIVMGIGFLSILLTTRHISMRKPKLFWISAASPLASVIISTLLVYLIRSKTHAISFIGHLPKGLNPPSLNMLYFSGAHLALAIKTGIITGILSLTEGIAVGRTFASLKNYQVNGNKEMMAIGFMNMAGSCTSCYVTTGSFSRSAVNYNAGAKTAVSNIVMASAVLVTLLFLMPLFYYTPNVILAAIILTAVIGLIDYQAAYKLWKVDKFDFFTCLCSFFGVLFVSVPLGLAIAVAVSVIKILLHVTRPNTSEFGNIPGTQIYQSLGRYREASRIPGFLILAIESPIYFANSTYLQDRILRWAREEENRIKENNGTTLKCIILDMTAVSAIDTSGLEAVFELRRRLEKQSLQLVLVNPVGTVMEKLHKSKIIEALGLSGLYLTVGEAVADLSSTWKANGQP", "length": 653 }, "evidence": [ { "id": "E1BDR3", "url": "https://omabrowser.org/oma/group/E1BDR3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ], "pmid": "" }, { "name": "sulfate transmembrane transport", "id": "GO:1902358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902358", "evidence": [ { "database": "UniProtKB", "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "oxalate transmembrane transporter activity", "id": "GO:0019531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019531", "evidence": [ { "database": "UniProtKB", "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ], "pmid": "" }, { "name": "sulfate transmembrane transporter activity", "id": "GO:0015116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015116", "evidence": [ { "database": "UniProtKB", "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ], "pmid": "" }, { "name": "chloride:bicarbonate antiporter activity", "id": "GO:0140900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140900", "evidence": [ { "database": "UniProtKB", "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ], "pmid": "" }, { "name": "sulfate:bicarbonate antiporter activity", "id": "GO:0015383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015383", "evidence": [ { "database": "UniProtKB", "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ], "pmid": "" }, { "name": "secondary active sulfate transmembrane transporter activity", "id": "GO:0008271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008271", "evidence": [ { "database": "UniProtKB", "id": "E1BDR3", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDR3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 706, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDR3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDR3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDR3" }, { "id": "PS50801", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50801" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "STAS", "eco_id": "ECO_0000259", "start_pos": 540, "end_pos": 692, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 163, "end_pos": 165 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK57-1", "uniprot_ac": "E1BK57", "uniprot_id": "E1BK57_BOVIN", "mass": { "chemical_mass": 77551.0, "monoisotopic_mass": 77551.0 }, "refseq": { "ac": "XP_024833524", "name": "T-box transcription factor TBX3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833524" }, "gene_names": [ { "name": "TBX3", "type": "recommended", "evidence": [ { "id": "E1BK57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ] }, { "name": "TBX3", "type": "synonym", "evidence": [ { "id": "XP_024833524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833524" } ] } ], "protein_names": [ { "name": "T-box transcription factor 3", "type": "synonym", "evidence": [ { "id": "E1BK57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK57/entry#names_and_taxonomy" } ] }, { "name": "T-box transcription factor TBX3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024833524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833524" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TBX3", "url": "https://www.uniprot.org/uniprotkb/E1BK57", "locus": { "chromosome": "17", "start_pos": 60101468, "end_pos": 60088665, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021706", "url": "https://www.ensembl.org/id/ENSBTAG00000021706" } ] } } ], "crossref": [ { "id": "E1BK57", "url": "https://alphafold.ebi.ac.uk/entry/E1BK57", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021706", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021706", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20188", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20188", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "781063", "url": "https://www.ncbi.nlm.nih.gov/gene/781063", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:781063", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781063", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QGIAMSP", "url": "https://omabrowser.org/oma/group/QGIAMSP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M881", "url": "https://www.orthodb.org/?gene=A0A3Q1M881", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267:SF91", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267:SF91", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9856649", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9856649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024833524", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833524", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M881", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M881", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M881-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M881-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK57-1", "url": "https://www.uniprot.org/uniprotkb/E1BK57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQTHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDDRHKKENGTSDESSSEQAAFNCFAQSSSPAVSTVGTSNLKDLCPSEGESDAEADSKEEHGPEACDTAKISTTTSEDPCRDKGSPAVKAHLFAAEPGGRARDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPGRDSAATSKAAEEARVLPGKEAFAPLTVQTDPAAAHLGQGPLPGLGFAPGLAGQQFFNGHPLFLHPGQFAMGGAFSSMAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPLPVPDSSGLLTTALPSMAAAAATAGPLDGKAAALAASPASVAVDSGSELNSRSSTLSSSSVSLSPKLCPEKEAATSELQNIQRLVSGLEAKPDRSRSASP", "length": 728, "header": "tr|E1BK57-1|E1BK57_BOVIN Isoform 1 of T-box transcription factor 3 OS=Bos taurus OX=9913 GN=TBX3 PE=4 SV=3 CANONICAL=E1BK57-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M881-1", "url": "https://www.uniprot.org/uniprotkb/E1BK57/entry#A0A3Q1M881-1", "sequence": { "sequence": "MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQTHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDQATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDDRHKKENGTSDESSSEQAAFNCFAQSSSPAVSTVGTSNLKDLCPSEGESDAEADSKEEHGPEACDTAKISTTTSEDPCRDKGSPAVKAHLFAAEPGGRARDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPGRDSAATSKAAEEARVLPGKEAFAPLTVQTDPAAAHLGQGPLPGLGFAPGLAGQQFFNGHPLFLHPGQFAMGGAFSSMAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPLPVPDSSGLLTTALPSMAAAAATAGPLDGKAAALAASPASVAVDSGSELNSRSSTLSSSSVSLSPKLCPEKEAATSELQNIQRLVSGLEAKPDRSRSASP", "length": 748, "header": "tr|A0A3Q1M881-1|E1BK57_BOVIN Computationally mapped isoform of T-box transcription factor 3 OS=Bos taurus OX=9913 GN=TBX3 PE=4 SV=1 CANONICAL=E1BK57-1" }, "locus": { "chromosome": "17", "start_pos": 60100464, "end_pos": 60088864, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077533.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077533.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064625.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064625.1" } ] } }, { "isoform_ac": "E1BK57-1", "url": "https://www.uniprot.org/uniprotkb/E1BK57/entry#E1BK57-1", "sequence": { "sequence": "MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQTHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDDRHKKENGTSDESSSEQAAFNCFAQSSSPAVSTVGTSNLKDLCPSEGESDAEADSKEEHGPEACDTAKISTTTSEDPCRDKGSPAVKAHLFAAEPGGRARDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPGRDSAATSKAAEEARVLPGKEAFAPLTVQTDPAAAHLGQGPLPGLGFAPGLAGQQFFNGHPLFLHPGQFAMGGAFSSMAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPLPVPDSSGLLTTALPSMAAAAATAGPLDGKAAALAASPASVAVDSGSELNSRSSTLSSSSVSLSPKLCPEKEAATSELQNIQRLVSGLEAKPDRSRSASP", "length": 728, "header": "tr|E1BK57-1|E1BK57_BOVIN Isoform 1 of T-box transcription factor 3 OS=Bos taurus OX=9913 GN=TBX3 PE=4 SV=3 CANONICAL=E1BK57-1" }, "locus": { "chromosome": "17", "start_pos": 60100464, "end_pos": 60088864, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028930.8", "url": "https://www.ensembl.org/id/ENSBTAT00000028930.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028930.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028930.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:781063", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781063", "resource": "KEGG Pathway" }, { "id": "R-BTA-9856649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9856649", "resource": "Reactome", "description": "Transcriptional and post-translational regulation of MITF-M expression and activity" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NXF3-1", "protein_name": "T-box transcription factor 3", "gene_name": "TBX3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNIPMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALALPPNGAAALSLPGALAKPIMDQLVGAAETAIPFSSLGHQAAAHLRPLKTLEPEEEVEDDPKVHLEAKELWEQFHKRGTEMVITKSGRRMFPPFKVRCTGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVYDERQKKENPTSDESSNEQTAFKCFAQSSCPAVPAVGTSSLKDLCPSEGDSDADSKDDPLLEASESGKISTTTATTPAPASSGAAASDDPRDKGGSPSKSHFFPSDSATSRSRERTEKAPPDSRHSPATISSSSRGGGLSGEELKSPLRDGPKVDENRLLGKEPFAPLTVQTDSTAHLSQGHLQNLGFPPALAGQQFFNPLGSGHPLLLHPGQFAMGGAFSGMAAGMGPLLATVSGASAGGSGLDSTVMATAAAQGLSGASTAALPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAASNSVHRHPFLNAVRPRLRYSPYPLPVPLPDGSSLLTTAMPGALAATSGETKGSALASSPGAVPLDSASDLTSRSSTLSSGSVSLSPKLGADKEAATSELQNIQRLVSGLDPKQDRSRSGSP", "length": 732 }, "evidence": [ { "id": "E1BK57", "url": "https://omabrowser.org/oma/group/E1BK57/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B8JKS6-1", "protein_name": "T-box transcription factor TBX3a", "gene_name": "tbx3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRDPVIQGSSMAYHPFLPHRGPEFAMSAMLGHQPPFFPALALPPNGSLSLPGALGKPIMEQLMGAAETGLHFSSLGHQAAHLRPLKTLEPEEEVEDDPKVHLEAKELWELFHKRGTEMVITKSGRRMFPPFKVRCTGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVNFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDHNPFAKGFRDTGNGRREKRKQLALQSMRSYEEQQKKENGTSDDSSGEQASFKCFRQASSPAVSTAGHNHLKDFCDSDEDSDEEDKDANAKEGPDSSKISTTTEDSKDQDAGLGKSVFGESDSSSGRRSEKTRADSRSPITLISSTTRSGEELKSPVREPAKTTDDCRTVSKENYMPLTVQTDGAAHLNQNHLHNFGFPPGLAGQQFFNHLGGAHPFLLHPSQFNMGGAFSNMAAGMGPILAAVSSGGVGSLDGSSLPSPSQSLTGAPMPFHLQQHVLASQGLAMSPFGGLFPYPYTYMAAAAAASSAASSSVHRHPFLSAVRPRLRYSPYSLPSVPDSTLLTTAMQPMASSGLEVKGDGMNTSPASAALDSEVTSRSSGSVSLSPKTCTEKDSSSELQSIQRLVSGLEPKPDRARSVSP", "length": 689 }, "evidence": [ { "id": "E1BK57", "url": "https://omabrowser.org/oma/group/E1BK57/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O15119-1", "protein_name": "T-box transcription factor TBX3", "gene_name": "TBX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTVGTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPGKEAFAPLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPSQFAMGGAFSSMAAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTALPSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSELQSIQRLVSGLEAKPDRSRSASP", "length": 743 }, "evidence": [ { "id": "E1BK57", "url": "https://omabrowser.org/oma/group/E1BK57/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70324-1", "protein_name": "T-box transcription factor TBX3", "gene_name": "Tbx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEDVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFEERHKKETSDESSSEQAAFNCFAQASSPAVSIVGTSNLKDLCPSEAESDAEAESKEEHGPEACDAAKISTTTAEEPGRDKGSPATRAQLFPAEPSRARDTARLDKASPDSRHSPATISSSTRVPGADERRSPGREGPVATKVDEARAIPAKDAFAPLSVQTDATAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPGQFAMGGAFSSMAAGMGPLLATVSGASTGVSGLESTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASTAAASSSVHRHPFLNLNSMRPRLRYSPYSIPVPVPDSSSLLATALPSMASAAGPLDGKAAALAASPASVAVDSGSELNSRSSTLSSGSVSLSPKLCSEKEAATSELQSIQRLVSGLEAKPDRSCSGSP", "length": 741 }, "evidence": [ { "id": "E1BK57", "url": "https://omabrowser.org/oma/group/E1BK57/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TST9-1", "protein_name": "T-box transcription factor TBX3", "gene_name": "Tbx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEDVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKETGTSDESSSEQAAFNCFAQASSPAVSTVGTSNLKDLCPSEAESDAEAESKEEHGPEACDTAKISTTTAEEPGRDKGSPATRAQLFPAEPSRARDTARLDKASPDSRHSPATISSSTRVPGADEHRSPGREGPVSAKVDEARALPAKDAFAPLSVQTDATAHLTQGPLPGLGFAPGLAGQQFFNGHPLFLHPGQFAMGGAFSSMAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNSMRPRLRYSPYSIPVPVPDSSSLLATALPSMASAAGPLDGKSAVLAASPASVAVDSGSELNSRSSTLSSGSVSLSPKLCSEKEAATSELQSIQRLVSGLEAKPDRSCSGSP", "length": 743 }, "evidence": [ { "id": "E1BK57", "url": "https://omabrowser.org/oma/group/E1BK57/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 29, "go_terms": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "luteinizing hormone secretion", "id": "GO:0032275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032275", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "follicle-stimulating hormone secretion", "id": "GO:0046884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046884", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "female genitalia development", "id": "GO:0030540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030540", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "semicircular canal morphogenesis", "id": "GO:0048752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048752", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "mesoderm morphogenesis", "id": "GO:0048332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048332", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "sinoatrial node cell development", "id": "GO:0060931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060931", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "embryonic forelimb morphogenesis", "id": "GO:0035115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035115", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "positive regulation of cell cycle", "id": "GO:0045787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045787", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "embryonic digit morphogenesis", "id": "GO:0042733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042733", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "cardiac epithelial to mesenchymal transition", "id": "GO:0060317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060317", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "cellular senescence", "id": "GO:0090398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090398", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "negative regulation of myoblast differentiation", "id": "GO:0045662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045662", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "male genitalia development", "id": "GO:0030539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030539", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "mammary gland development", "id": "GO:0030879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030879", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "atrioventricular canal morphogenesis", "id": "GO:1905222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905222", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "endocardial cushion formation", "id": "GO:0003272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003272", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "negative regulation of cell proliferation involved in heart morphogenesis", "id": "GO:2000137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000137", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "regulation of protein complex stability", "id": "GO:0061635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061635", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "anterior/posterior axis specification, embryo", "id": "GO:0008595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008595", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "cardiac jelly development", "id": "GO:1905072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905072", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BK57", "url": "https://www.uniprot.org/uniprotkb/E1BK57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BK57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK57" }, { "id": "PS50252", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50252" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-box", "eco_id": "ECO_0000259", "start_pos": 107, "end_pos": 285, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 }, { "start_pos": 313, "end_pos": 315 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BL76-1", "uniprot_ac": "E1BL76", "uniprot_id": "E1BL76_BOVIN", "mass": { "chemical_mass": 60002.0, "monoisotopic_mass": 60002.0 }, "refseq": { "ac": "NP_001178344", "name": "M-phase inducer phosphatase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178344" }, "gene_names": [ { "name": "CDC25B", "type": "recommended", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] }, { "name": "CDC25B", "type": "synonym", "evidence": [ { "id": "NP_001178344", "database": "RefSeq", "url": 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Directly dephosphorylates CDK1 and stimulates its kinase activity. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. The three isoforms seem to have a different level of activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMN3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN3#function" }, { "database": "UniProtKB", "id": "ARBA00056746", "url": "https://www.uniprot.org/uniprotkb/ARBA00056746#function" }, { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76#function" }, { "database": "UniProtKB", "id": "A0A3Q1MCU3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCU3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CDC25B", "url": "https://www.uniprot.org/uniprotkb/E1BL76", "locus": { "chromosome": "13", "start_pos": 51395121, "end_pos": 51404718, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008436", "url": "https://www.ensembl.org/id/ENSBTAG00000008436" } ] } } ], "crossref": [ { "id": "E1BL76", "url": "https://alphafold.ebi.ac.uk/entry/E1BL76", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008436", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008436", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01530", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01530", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505847", "url": "https://www.ncbi.nlm.nih.gov/gene/505847", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505847", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505847", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHSKCRR", "url": "https://omabrowser.org/oma/group/MHSKCRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMN3", "url": "https://www.orthodb.org/?gene=A0A3Q1LMN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MCU3", "url": "https://www.orthodb.org/?gene=A0A3Q1MCU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BL76", "url": "https://www.orthodb.org/?gene=E1BL76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10828", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL76-1", "url": "https://www.uniprot.org/uniprotkb/E1BL76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELPQPESVAGSALSPAGMRGGAQRPGHLPGLGLGAHGLLGSPERAAASSPVTTLTQTMHHLAGLGSETPKSQVGSLLTCLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPNMAEQTFEQAIQAASRVIQNEQFAIRRFQSLPDGFVFKMPGKLKHPSHSRALGEWASRREAFAQRPSSAPDLMCLTPERKMEVEELIPLARCQFSVTPSTGAVEEDDGFVDILETDLKENDVVPPGMESLISAPLVKTSEKEEEQDLIMYSKCQRLFRSPSMPCGVIRPILKRLERPQDRDLPVQNKRKRSVTPPEEELQEAEEPKARILRSKSLCHDEIENILDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETVVALLTGKFSHIVEKFVIVDCRYPYEYEGGHIKTAVNLPLERDAETFLLQSPITPCSLDKRIILIFHCEFSSERGPRMCRFIRERDRASNDYPSLYYPEMYILKGGYKDFFPQHPTFCEPQDYRPMNHEDFKDEMKTFRLKTRSWAGERSRRELCSRLQDQ", "length": 533, "header": "tr|E1BL76-1|E1BL76_BOVIN Isoform 1 of M-phase inducer phosphatase OS=Bos taurus OX=9913 GN=CDC25B PE=3 SV=2 CANONICAL=E1BL76-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMN3-1", "url": "https://www.uniprot.org/uniprotkb/E1BL76/entry#A0A3Q1LMN3-1", "sequence": { "sequence": "MELPQPESVAGSALSPAGMRGGAQRPGHLPGLGLGAHGLLGSPERAAASSPVTTLTQTMHHLAGLGSETPKSQVGSLLTCLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPNMAEQTFEQAIQAASRVIQNEQFAIRRFQSLPGRLLGHSPVLRNITNSQASGTWRKTEACDQAAHGSGEDKENDGFVFKMPGKLKHPSHSRALGEWASRREAFAQRPSSAPDLMCLTPERKMEVEELIPLARCQFSVTPSTGAVEEDDGFVDILETDLKENDVVPPGMESLISAPLVKTSEKEEEQDLIMYSKCQRLFRSPSMPCGVIRPILKRLERPQDRDLPVQNKRKRSVTPPEEELQEAEEPAFLLQTVDGKHQDLKYISPETVVALLTGKFSHIVEKFVIVDCRYPYEYEGGHIKTAVNLPLERDAETFLLQSPITPCSLDKRIILIFHCEFSSERGPRMCRFIRERDRASNDYPSLYYPEMYILKGGYKDFFPQHPTFCEPQDYRPMNHEDFKDEMKTFRLKTRSWAGERSRRELCSRLQDQ", "length": 542, "header": "tr|A0A3Q1LMN3-1|E1BL76_BOVIN Computationally mapped isoform of M-phase inducer phosphatase OS=Bos taurus OX=9913 GN=CDC25B PE=3 SV=1 CANONICAL=E1BL76-1" }, "locus": { "chromosome": "13", "start_pos": 51404499, "end_pos": 51396269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079047.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079047.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061150.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061150.1" } ] } }, { "isoform_ac": "A0A3Q1MCU3-1", "url": "https://www.uniprot.org/uniprotkb/E1BL76/entry#A0A3Q1MCU3-1", "sequence": { "sequence": "MELPQPESVAGSALSPAGMRGGAQRPGHLPGLGLGAHGLLGSPERAAASSPVTTLTQTMHHLAGLGSETPKSQVGSLLTCLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPNMAEQTFEQAIQAASRVIQNEQFAIRRFQSLPGRLLGHSPVLRNITNSQASGTWRKTEACDQAAHGSGEDKENDGFVFKMPGKLKHPSHSRALGEWASRREAFAQRPSSAPDLMCLTPERKMEVEELIPLARCQFSVTPSTGAVEEDDGFVDILETDLKENDVVPPGMESLISAPLVKTSEKEEEQDLIMYSKCQRLFRSPSMPCGVIRPILKRLERPQDRDLPVQNKRKRSVTPPEEELQEAEEPKARILRSKSLCHDEIENILDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETVVALLTGKFSHIVEKFVIVDCRYPYEYEGGHIKTAVNLPLERDAETFLLQSPITPCSLDKRIILIFHCEFSSERGPRMCRFIRERDRASNDYPSLYYPEMYILKGGYKDFFPQHPTFCEPQDYRPMNHEDFKDEMKTFRLKTRSWAGERSRRELCSRLQDQ", "length": 574, "header": "tr|A0A3Q1MCU3-1|E1BL76_BOVIN Computationally mapped isoform of M-phase inducer phosphatase OS=Bos taurus OX=9913 GN=CDC25B PE=3 SV=1 CANONICAL=E1BL76-1" }, "locus": { "chromosome": "13", "start_pos": 51404499, "end_pos": 51396269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075264.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075264.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068685.1", "url": "https://www.ensembl.org/id/ENSBTAP00000068685.1" } ] } }, { "isoform_ac": "A0AAA9S7T2-1", "url": "https://www.uniprot.org/uniprotkb/E1BL76/entry#A0AAA9S7T2-1", "sequence": { "sequence": "MELPQPESVAGSALSPAGMRGGAQRPGHLPGLGLGAHGLLGSPERAAASSPVTTLTQTMHHLAGLGSETPKSQVGSLLTCLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPNMAEQTFEQAIQAASRVIQNEQFAIRRFQSLPGRLLGHSPVLRNITNSQASGTWRKTEACDQAAHGSGEDKENDGFVFKMPGKLKHPSHSRALGEWASRREAFAQRPSSAPDLMCLTPERKMEVEELIPLARCQFSVTPSTGAVEEDDGFVDILETDLKENDVVPPGMESLISAPLVKTSEKEEEQDLIMYSKCQRLFRSPSMPCGVIRPILKRLERPQDRDLPVQNKRKRSVTPPEEELQEAEEPKARILRSKSLCHDEIENILDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETTAVNLPLERDAETFLLQSPITPCSLDKRIILIFHCEFSSERGPRMCRFIRERDRASNDYPSLYYPEMYILKGGYKDFFPQHPTFCEPQDYRPMNHEDFKDEMKTFRLKTRSWAGERSRRELCSRLQDQ", "length": 541, "header": "tr|A0AAA9S7T2-1|E1BL76_BOVIN Computationally mapped isoform of M-phase inducer phosphatase OS=Bos taurus OX=9913 GN=CDC25B PE=3 SV=1 CANONICAL=E1BL76-1" }, "locus": { "chromosome": "13", "start_pos": 51404499, "end_pos": 51396269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094068.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094068.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078207.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078207.1" } ] } }, { "isoform_ac": "E1BL76-1", "url": "https://www.uniprot.org/uniprotkb/E1BL76/entry#E1BL76-1", "sequence": { "sequence": "MELPQPESVAGSALSPAGMRGGAQRPGHLPGLGLGAHGLLGSPERAAASSPVTTLTQTMHHLAGLGSETPKSQVGSLLTCLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPNMAEQTFEQAIQAASRVIQNEQFAIRRFQSLPDGFVFKMPGKLKHPSHSRALGEWASRREAFAQRPSSAPDLMCLTPERKMEVEELIPLARCQFSVTPSTGAVEEDDGFVDILETDLKENDVVPPGMESLISAPLVKTSEKEEEQDLIMYSKCQRLFRSPSMPCGVIRPILKRLERPQDRDLPVQNKRKRSVTPPEEELQEAEEPKARILRSKSLCHDEIENILDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETVVALLTGKFSHIVEKFVIVDCRYPYEYEGGHIKTAVNLPLERDAETFLLQSPITPCSLDKRIILIFHCEFSSERGPRMCRFIRERDRASNDYPSLYYPEMYILKGGYKDFFPQHPTFCEPQDYRPMNHEDFKDEMKTFRLKTRSWAGERSRRELCSRLQDQ", "length": 533, "header": "tr|E1BL76-1|E1BL76_BOVIN Isoform 1 of M-phase inducer phosphatase OS=Bos taurus OX=9913 GN=CDC25B PE=3 SV=2 CANONICAL=E1BL76-1" }, "locus": { "chromosome": "13", "start_pos": 51404499, "end_pos": 51396269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011100.6", "url": "https://www.ensembl.org/id/ENSBTAT00000011100.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011100.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011100.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 426, "start_aa": "Thr", "end_pos": 426, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr426", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:505847", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505847", "resource": "KEGG Pathway" }, { "id": "R-BTA-69273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69273", "resource": "Reactome", "description": "Cyclin A/B1/B2 associated events during G2/M transition" }, { "id": "R-BTA-69656", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69656", "resource": "Reactome", "description": "Cyclin A:Cdk2-associated events at S phase entry" } ], "orthologs": [ { "uniprot_canonical_ac": "P30305-1", "protein_name": "M-phase inducer phosphatase 2", "gene_name": "CDC25B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ", "length": 580 }, "evidence": [ { "id": "E1BL76", "url": "https://omabrowser.org/oma/group/E1BL76/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P30306-1", "protein_name": "M-phase inducer phosphatase 2", "gene_name": "Cdc25b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVPLQKSAPGSALSPARVLGGIQRPRHLSVFEFESDGFLGSPEPTASSSPVTTLTQTMHNLAGLGSEPPKAQVGSLSFQNRLADLSLSRRTSECSLSSESSESSDAGLCMDSPSPVDPQMAERTFEQAIQAASRVIQNEQFTIKRFRSLPVRLLEHSPVLQSITNSRALDSWRKTEAGYRAAANSPGEDKENDGYIFKMPQELPHSSSAQALAEWVSRRQAFTQRPSSAPDLMCLTTEWKMEVEELSPVAQSSSLTPVERASEEDDGFVDILESDLKDDEKVPAGMENLISAPLVKKLDKEEEQDLIMFSKCQRLFRSPSMPCSVIRPILKRLERPQDRDVPVQSKRRKSVTPLEEQQLEEPKARVFRSKSLCHEIENILDSDHRGLIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVEKFVIVDCRYPYEYEGGHIKNAVNLPLERDAETFLLQRPIMPCSLDKRIILIFHCEFSSERGPRMCRFIRERDRAANDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFRDELRNFRLKTRSWAGERSRRELCSRLQDQ", "length": 576 }, "evidence": [ { "id": "E1BL76", "url": "https://omabrowser.org/oma/group/E1BL76/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48966-1", "protein_name": "M-phase inducer phosphatase 2", "gene_name": "Cdc25b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPPQKSAPGSALSTARVLGGIQRPRHLSGFGFGSDGLLGSPERAASSSPVTTLTQTMYNLAGLGSETPKTQVGSLSFQNRLTDLSLSRRTSECSLSSESSESSDAGLCMDSPSPMDPQTAERTFEQAIQAASRVIQKMQFTIKASVFASEAAGHSPVLQNITNSQALDSWEKDEAGYRAASSPGEDKENDGYIFKMPQKLPHSSSARALAEWASRREAFTQRPSSAPDLMCLTTDGKMDVEEASPVAQSSSLTPVERACEEDDGFVDILESDLKDDDMVPAGMENLISAPLVKKLDKEEEQDLIMFSKCQRLFRSPSMPCSVIRPILKRLERPHDRDVPVLSKRRKSGTPLEEQQLEEPKARVFRSKSLCHEIESILDSDHRGLIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVEKFVIVDCRYPYEYEGGHIKNAVNLPLEPDAETFLLKHPITPCNLDKRIILIFHCEFSSERGPRMCRFIRERDRAANDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHAAFRDELRNFRLKTRSWAGERSTTQLCSRLQDQ", "length": 574 }, "evidence": [ { "id": "E1BL76", "url": "https://omabrowser.org/oma/group/E1BL76/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" }, { "name": "positive regulation of cell cycle G2/M phase transition", "id": "GO:1902751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902751", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" }, { "name": "positive regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010971", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" }, { "name": "positive regulation of cytokinesis", "id": "GO:0032467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032467", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" }, { "name": "positive regulation of G2/MI transition of meiotic cell cycle", "id": "GO:0110032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110032", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E1BL76", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1ME76-1", "F1MRH9-1", "A0AAF6DLF7-1", "A0AAA9S9Q3-1", "E1BFE2-1", "E1BL76-1", "G3MXS7-1", "A0A3Q1LUB1-1", "A0AAA9THG9-1", "F1N339-1", "F6RY99-1", "A0AAF6YUC8-1", "A0AAA9RTM1-1", "A0AAA9SMJ6-1", "A0A3Q1LZA9-1", "A7MBD1-1", "A5D7P0-1", "Q58DB6-1", "A0AAA9SEK4-1", "E1BDH9-1", "F1MGK4-1", "E1BIH4-1", "A0A3Q1M6K1-1", "E1BIU8-1", "A7MBJ4-1", "A6H730-1", "A0A3Q1MFX2-1", "A0AAA9U0H6-1", "A2VDT1-1", "E1BPU9-1", "P0C591-1", "P11064-1", "Q0IID7-1", "Q2KJ36-1", "Q2T9S4-1", "E1BPA0-1", "A0AAA9TAZ9-1", "Q5BIP9-1", "A0A3Q1M5K4-1", "F1MM08-1", "E1BJR7-1", "Q17QJ3-1", "Q17QM8-1", "F1MD22-1", "F1MI99-1", "F1MP34-1", "F1MGK5-1", "F1MEZ2-1", "F1MQM7-1", "E1BEZ8-1", "A0A3Q1M0B4-1", "A0AAA9S7W5-1", "A0A3Q1N8V6-1", "A0AAA9TFV5-1", "A0A3Q1MBB1-1", "F1MTZ3-1", "A0AAF6Z8C2-1", "F1MDF1-1", "A0AAA9T5N9-1", "E1BKT4-1", "A0A3Q1MH98-1", "F1N6L3-1", "F1MW70-1", "F1MXF2-1", "A0AAA9TWD1-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-BTA-170120", "name": "Translocation of Cdc25B to the cytoplasm", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nuclear envelope", "input_participant_list": [], "output_participant_list": [ "R-BTA-157412" ], "enzyme_list": [ "E1BL76-1" ], "evidence": [ { "id": "R-BTA-170120", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170120" } ] }, { "id": "R-BTA-170153", "name": "Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5D7P0-1", "A7MBD1-1", "P48734-1", "E1BL76-1" ], "evidence": [ { "id": "R-BTA-170153", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170153" } ] }, { "id": "R-BTA-170159", "name": "Translocation of Cdc25 to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nuclear envelope", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5D7P0-1", "A7MBD1-1", "E1BL76-1" ], "evidence": [ { "id": "R-BTA-170159", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170159" } ] }, { "id": "R-BTA-170161", "name": "Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P48734-1", "E1BL76-1" ], "evidence": [ { "id": "R-BTA-170161", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170161" } ] }, { "id": "R-BTA-174110", "name": "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A7MBD1-1", "Q5E9Y0-1", "E1BL76-1" ], "evidence": [ { "id": "R-BTA-174110", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174110" } ] }, { "id": "R-BTA-9929935", "name": "CCNA:CDK1 phosphorylates CDC25B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-BTA-69734" ], "output_participant_list": [ "R-BTA-9929936" ], "enzyme_list": [ "P48734-1", "E1BL76-1" ], "evidence": [ { "id": "R-BTA-9929935", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9929935" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-157412", "participant_name": "CDC25B [cytosol]", "crossref": [ { "id": "ENSBTAG00000008436", "database": "ENSEMBL", "url": "" }, { "id": "A0A3Q1MCU3", "database": "UniProt", "url": "" }, { "id": "XP_005214622.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAP00000068685", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000075264", "database": "ENSEMBL", "url": "" }, { "id": "27063", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-69734", "participant_name": "CDC25B [nucleoplasm]", "crossref": [ { "id": "A0A3Q1MCU3", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000008436", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000068685", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000075264", "database": "ENSEMBL", "url": "" }, { "id": "XP_005214622.1", "database": "RefSeq", "url": "" }, { "id": "27063", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-9929936", "participant_name": "phospho-CDC25B [nucleoplasm]", "crossref": [ { "id": "ENSBTAG00000008436", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000075264", "database": "ENSEMBL", "url": "" }, { "id": "27063", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000068685", "database": "ENSEMBL", "url": "" }, { "id": "A0A3Q1MCU3", "database": "UniProt", "url": "" }, { "id": "XP_005214622.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LUB1", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] } ] }, { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B4", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] } ] }, { "uniprot_ac": "A0A3Q1M5K4", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] } ] }, { "uniprot_ac": "A0A3Q1M6K1", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] } ] }, { "uniprot_ac": "A0A3Q1MBB1", "gene_name": "TNS2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] } ] }, { "uniprot_ac": "A0A3Q1MFX2", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1N8V6", "gene_name": "LOC101903026", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S7W5", "gene_name": "PTPRV", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] } ] }, { "uniprot_ac": "A0AAA9S9Q3", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] } ] }, { "uniprot_ac": "A0AAA9SEK4", "gene_name": "PTPRE", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] } ] }, { "uniprot_ac": "A0AAA9SMJ6", "gene_name": "PTPRH", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] } ] }, { "uniprot_ac": "A0AAA9T5N9", "gene_name": "", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] } ] }, { "uniprot_ac": "A0AAA9TAZ9", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] } ] }, { "uniprot_ac": "A0AAA9TFV5", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] } ] }, { "uniprot_ac": "A0AAA9THG9", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] } ] }, { "uniprot_ac": "A0AAA9TWD1", "gene_name": "PTPN20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YUC8", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] } ] }, { "uniprot_ac": "A0AAF6Z8C2", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] } ] }, { "uniprot_ac": "A2VDT1", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] } ] }, { "uniprot_ac": "A5D7P0", "gene_name": "CDC25C", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] } ] }, { "uniprot_ac": "A6H730", "gene_name": "ACP3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] } ] }, { "uniprot_ac": "A7MBD1", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] } ] }, { "uniprot_ac": "A7MBJ4", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] } ] }, { "uniprot_ac": "E1BDH9", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] } ] }, { "uniprot_ac": "E1BEZ8", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] } ] }, { "uniprot_ac": "E1BFE2", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] } ] }, { "uniprot_ac": "E1BIH4", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] } ] }, { "uniprot_ac": "E1BIU8", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] } ] }, { "uniprot_ac": "E1BJR7", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] } ] }, { "uniprot_ac": "E1BKT4", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] } ] }, { "uniprot_ac": "E1BL76", "gene_name": "CDC25B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] } ] }, { "uniprot_ac": "E1BPA0", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] } ] }, { "uniprot_ac": "E1BPU9", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] } ] }, { "uniprot_ac": "F1MD22", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] } ] }, { "uniprot_ac": "F1MDF1", "gene_name": "PTPN18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MGK4", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] } ] }, { "uniprot_ac": "F1MGK5", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MRH9", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] } ] }, { "uniprot_ac": "F1MTZ3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1MXF2", "gene_name": "MDP1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] } ] }, { 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"Serine/threonine-protein kinase TAO3", "type": "recommended", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1/entry#names_and_taxonomy" } ] }, { "name": "Thousand and one amino acid protein 3", "type": "synonym", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHE1", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TAOK3", "url": "https://www.uniprot.org/uniprotkb/E1BHE1", "locus": { "chromosome": "17", "start_pos": 57072044, "end_pos": 56979996, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012550", "url": "https://www.ensembl.org/id/ENSBTAG00000012550" } ] } } ], "crossref": [ { "id": "E1BHE1", "url": "https://alphafold.ebi.ac.uk/entry/E1BHE1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012550", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012550", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06633", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06633", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "E1BHE1", "url": "https://www.ebi.ac.uk/intact/interactors/id:E1BHE1*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534620", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534620", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEKIKEX", "url": "https://omabrowser.org/oma/group/KEKIKEX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPH8", "url": "https://www.orthodb.org/?gene=A0A3Q1LPH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BHE1", "url": "https://www.orthodb.org/?gene=E1BHE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47167:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47167:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LPH8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHE1", "url": "https://www.uniprot.org/uniprotkb/E1BHE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHE1-1", "url": "https://www.uniprot.org/uniprotkb/E1BHE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKGVPRDPEIADLFYKDDPEELFIGLHEIGHGSFGAVYFKWQDILKEVKFLQQLRHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEMEIAAITHGALQGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIEMAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKMPQERPTSAELLRHDFVRRDRPLRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLSRELDSLGSNHSIPSMSVSTGSQGSSVNSMQEVMDDSSSELVMMHDDESPVNSTPSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKYLLERQEREIETFDMESLRMGFGNLVTLDFPKEDYR", "length": 874, "header": "tr|E1BHE1-1|E1BHE1_BOVIN Isoform 1 of Serine/threonine-protein kinase TAO3 OS=Bos taurus OX=9913 GN=TAOK3 PE=3 SV=2 CANONICAL=E1BHE1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BHE1/entry#A0A3Q1LPH8-1", "sequence": { "sequence": "MRKGVPRDPEIADLFYKDDPEELFIGLHEIGHGSFGAVYFATNAHTNEVVAIKKMSYSGKQAHEKWQDILKEVKFLQQLRHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEMEIAAITHGALQGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIEMAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKMPQERPTSAELLRHDFVRRDRPLRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLSRELDSLGSNHSIPSMSDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKYLLERQEREIETFDMESLRMGFGNLVTLDFPKEDYR", "length": 854, "header": "tr|A0A3Q1LPH8-1|E1BHE1_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase TAO3 OS=Bos taurus OX=9913 GN=TAOK3 PE=3 SV=2 CANONICAL=E1BHE1-1" }, "locus": { "chromosome": "17", "start_pos": 57070840, "end_pos": 56986804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079941.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079941.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061979.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061979.2" } ] } }, { "isoform_ac": "E1BHE1-1", "url": "https://www.uniprot.org/uniprotkb/E1BHE1/entry#E1BHE1-1", "sequence": { "sequence": "MRKGVPRDPEIADLFYKDDPEELFIGLHEIGHGSFGAVYFKWQDILKEVKFLQQLRHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEMEIAAITHGALQGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIEMAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKMPQERPTSAELLRHDFVRRDRPLRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLSRELDSLGSNHSIPSMSVSTGSQGSSVNSMQEVMDDSSSELVMMHDDESPVNSTPSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKYLLERQEREIETFDMESLRMGFGNLVTLDFPKEDYR", "length": 874, "header": "tr|E1BHE1-1|E1BHE1_BOVIN Isoform 1 of Serine/threonine-protein kinase TAO3 OS=Bos taurus OX=9913 GN=TAOK3 PE=3 SV=2 CANONICAL=E1BHE1-1" }, "locus": { "chromosome": "17", "start_pos": 57070840, "end_pos": 56986804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016661.7", "url": "https://www.ensembl.org/id/ENSBTAT00000016661.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016661.6", "url": "https://www.ensembl.org/id/ENSBTAP00000016661.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 367, "start_aa": "Thr", "end_pos": 367, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr367", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:534620", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534620", "resource": "KEGG Pathway" }, { "id": "R-BTA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-BTA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2TRY2-1", "protein_name": "Serine/threonine-protein kinase TAO3", "gene_name": "TAOK3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRKGVPKDPEIADLFYKDDPEEIFVGLHEIGHGSFGAVYFATNSHTNEVVAVKKMSYSGKQTNEKWQDIIKEVKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHCKIHRDIKAGNILLTEPGQVKLADFGSASIVSPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWSDSFRGFVDYCLQKIPQERPSSADLLRHDFVRRDRPPRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLTESQEEEEDSEHGSNLSRKMDSLGSNHSIPSMSVSTGSQSSSVSSMQEVLDESSPELVMMHSDESTVNSTSSVVQKKDHVFIRDEVGHRDRRPEVRPTQSVQNQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAVMEKEAKTAAADEKKFQQQILAQQKKDLATFLESQKKQYKLCKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLSQQRLYYDKNCRFFKRKTMIKRHELEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHFMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVTPKSEHKTILKSLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKFLLERQEREIETFDMESLRMGFGNLVTLDYPKEDYR", "length": 898 }, "evidence": [ { "id": "E1BHE1", "url": "https://omabrowser.org/oma/group/E1BHE1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A4X1TUN3-1", "protein_name": "Serine/threonine-protein kinase TAO3", "gene_name": "TAOK3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRKGVPKDPETADLFYKDDPEELFIGLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQAHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALHGLAYLHSHDLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIEMAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKMPQERPTSAELLRHDFVRRDRPLRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLRREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDDSSSELVMMHDEESPLNSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKYLLERQEREIETFDMESLRMGFGNLVTLDFPKEDYR", "length": 898 }, "evidence": [ { "id": "E1BHE1", "url": "https://omabrowser.org/oma/group/E1BHE1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q53UA7-1", "protein_name": "Serine/threonine-protein kinase TAO3", "gene_name": "Taok3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRKGVLKDPEIAELFFKEDPEELFIDLHEIGHGSFGAVYFATNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVRFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSREWTDSFRRFVDYCLHKIPQERPAAAELLRHDFIRRERPPRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEEEEDSEQGSNLNREVDSLGSIHSIPSVSVSTGSRSSSVNSMQEVMDEGSPELVMMQEDEGTVNSSSSMVHKKDHVFVRDEAGHGDPRPEPRPTQSVQSRALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVATIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDRNCRCFKRKIMTKRHEVEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKAILKTLKEEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKTLLERQERETETFDMESLRMGFGNLVTLDFPKEDYR", "length": 898 }, "evidence": [ { "id": "E1BHE1", "url": "https://omabrowser.org/oma/group/E1BHE1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BYC6-1", "protein_name": "Serine/threonine-protein kinase TAO3", "gene_name": "Taok3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRKGALKDPEIADLFFKDDPEELFIDLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSREWTDSFRRFVDYCLHKIPQERPAAVELLRHDFIRRERPPKVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEEEEDGEQGSNLNREVDSLGSIHSIPSTSVSTGSRSSSVNSMQEVMDESSSELVMMQEDEGTANSSASTVHKKDHVFVRDEAGHGDPRPEPRPTQSVQSRALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVATIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDRNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKAILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKTLLERQERETETFDMESLRMGFGNLVTLDFPKEDYR", "length": 898 }, "evidence": [ { "id": "E1BHE1", "url": "https://omabrowser.org/oma/group/E1BHE1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2K8-1", "protein_name": "Serine/threonine-protein kinase TAO3", "gene_name": "TAOK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRKGVLKDPEIADLFYKDDPEELFIGLHEIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESSSELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKNLLERQEREIETFDMESLRMGFGNLVTLDFPKEDYR", "length": 898 }, "evidence": [ { "id": "E1BHE1", "url": "https://omabrowser.org/oma/group/E1BHE1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E1BHE1", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BHE1", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BHE1", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ], "pmid": "" }, { "name": "lipid 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"A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", 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"A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-BTA-9014294", "name": "RAC2 binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P32871-1", "A0A3Q1M0G8-1", "Q08E52-1", "Q2KJ93-1", "E1BJ31-1", "A0A3Q1MFB9-1", "E1BHE1-1", "Q9TU25-1" ], "evidence": [ { "id": "R-BTA-9014294", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9014294" } ] }, { "id": "R-BTA-9018808", "name": "RAC3 binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "Q08E52-1", "Q2KJ93-1", "E1BJ31-1", "O46522-1", "E1BHE1-1" ], "evidence": [ { "id": "R-BTA-9018808", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9018808" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] } ] }, { "uniprot_ac": "A0A3Q1LWT7", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] } ] }, { "uniprot_ac": "A0A3Q1LYH3", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] } ] }, { "uniprot_ac": "A0A3Q1M0G8", "gene_name": "PAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "O46522", "gene_name": "CYBB", "activity": [ { "ec_number": "1.6.3.-", "activity": "", "evidence": [ { "id": "O46522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46522" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJ93", "gene_name": "CDC42", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q2KJ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ93" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q2KJ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ93" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q58D94", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] } ] }, { "uniprot_ac": "Q8MIT6", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] } ] }, { "uniprot_ac": "Q95KV0", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] } ] }, { "uniprot_ac": "Q9N0P9", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] } ] }, { "uniprot_ac": "Q9TU25", "gene_name": "RAC2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q9TU25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9TU25" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q9TU25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9TU25" } ] } ] }, { "uniprot_ac": "V6F977", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 253, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 367 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 479, "end_pos": 481 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFI2-1", "uniprot_ac": "E1BFI2", "uniprot_id": "E1BFI2_BOVIN", "mass": { "chemical_mass": 97456.0, "monoisotopic_mass": 97456.0 }, "refseq": {}, "gene_names": [ { "name": "DHTKD1", "type": "recommended", "evidence": [ { "id": "E1BFI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFI2" } ] } ], "protein_names": [ { "name": "2-oxoadipate dehydrogenase complex component E1", "type": "recommended", "evidence": [ { "id": "E1BFI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFI2/entry#names_and_taxonomy" } ] }, { "name": "2-oxoadipate dehydrogenase, mitochondrial", "type": "synonym", "evidence": [ { "id": "E1BFI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFI2/entry#names_and_taxonomy" } ] }, { "name": "Alpha-ketoadipate dehydrogenase", "type": "synonym", "evidence": [ { "id": "E1BFI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFI2/entry#names_and_taxonomy" } ] }, { "name": "Dehydrogenase E1 and transketolase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "E1BFI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFI2/entry#names_and_taxonomy" } ] }, { "name": "Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial", "type": "synonym", "evidence": [ { "id": "E1BFI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFI2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "2-oxoadipate dehydrogenase (E1a) component of the 2-oxoadipate dehydrogenase complex (OADHC). Participates in the first step, rate limiting for the overall conversion of 2-oxoadipate (alpha-ketoadipate) to glutaryl-CoA and CO(2) catalyzed by the whole OADHC. Catalyzes the irreversible decarboxylation of 2-oxoadipate via the thiamine diphosphate (ThDP) cofactor and subsequent transfer of the decarboxylated acyl intermediate on an oxidized dihydrolipoyl group that is covalently amidated to the E2 enzyme (dihydrolipoyllysine-residue succinyltransferase or DLST). Can catalyze the decarboxylation of 2-oxoglutarate in vitro, but at a much lower rate than 2-oxoadipate. Responsible for the last step of L-lysine, L-hydroxylysine and L-tryptophan catabolism with the common product being 2-oxoadipate.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1M6S6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6S6#function" }, { "database": "UniProtKB", "id": "ARBA00045379", "url": "https://www.uniprot.org/uniprotkb/ARBA00045379#function" }, { "database": "UniProtKB", "id": "A0A3Q1N7S2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7S2#function" }, { "database": "UniProtKB", "id": "A0A3Q1NLM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLM6#function" }, { "database": "UniProtKB", "id": "E1BFI2", "url": "https://www.uniprot.org/uniprotkb/E1BFI2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFI2", "url": "https://www.uniprot.org/uniprotkb/E1BFI2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DHTKD1", "url": "https://www.uniprot.org/uniprotkb/E1BFI2", "locus": { "chromosome": "13", "start_pos": 12236002, "end_pos": 12281750, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000291", "url": "https://www.ensembl.org/id/ENSBTAG00000000291" } ] } } ], "crossref": [ { "id": "E1BFI2", "url": "https://alphafold.ebi.ac.uk/entry/E1BFI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000291", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000291", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02016", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02016", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "517113", "url": "https://www.ncbi.nlm.nih.gov/gene/517113", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:517113", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517113", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PAQYYHV", "url": "https://omabrowser.org/oma/group/PAQYYHV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M6S6", "url": "https://www.orthodb.org/?gene=A0A3Q1M6S6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N7S2", "url": "https://www.orthodb.org/?gene=A0A3Q1N7S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23152", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23152", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23152:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23152:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00676", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00676", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16870", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16870", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9858328", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9858328", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "69576", "url": "https://www.rhea-db.org/rhea/69576", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M6S6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6S6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N7S2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N7S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NLM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NLM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFI2", "url": "https://www.uniprot.org/uniprotkb/E1BFI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFI2-1", "url": "https://www.uniprot.org/uniprotkb/E1BFI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWVAVAAARLGLGRASPLFLRRGYQTERGVYGYRPRKPESREPEGGLARPPGLLNMGKEEASLEEVVAYLNQIYCGQISIETSQLQSQEEKDWFAKRFEELKKEAFTTEERKHLSKLMLESQEFDHFLATKFATVKRYGGEGAESMMGFFYELLKMAAYSGVTDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENISAVGDVLSHLTSSVDLDFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSLDSSAQPGDKVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRAAQLAFEYQRQFRKDVIVDLLCYRQWGHNELDEPFFTNPGMYQIIRARKSIPDMYAEYLMANGLTTQEEVSEIKASYYVKLNGHLTHAAHYRPPATSLQAHWQGLVQPEACITSWNTGVPLDLLQFIGKKSVEVPEEFQIHSHLLKMHVQSRVEKVMDGTKLDWATAEALALGSLLAEGFNVRLSGQDVGRGTFSQRHAMVVCQKTDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPNLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVVLLPHGYDGAGPEHSSCRIERFLQMCDSTEEGVDGDTVNMCVAHPTTPAQYFHLLRRQMIRNFRKPLILVSPKTLLRLPAAVSTLQEMAPGTTFKPVIGDSSVDPKKVKSLVFCCGKHFYALMKQRESLEARKHDFAIIRIEELCPFPLDSLQQEMSKYKHVRDVIWSQEEPQNMGPWFFVSPRFEKQLACKLRLVSRPALPVPAVGIGTIHLQQHEEILTKTFNP", "length": 869, "header": "tr|E1BFI2-1|E1BFI2_BOVIN Isoform 1 of 2-oxoadipate dehydrogenase complex component E1 OS=Bos taurus OX=9913 GN=DHTKD1 PE=1 SV=3 CANONICAL=E1BFI2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M6S6-1", "url": "https://www.uniprot.org/uniprotkb/E1BFI2/entry#A0A3Q1M6S6-1", "sequence": { "sequence": "MAWVAVAAARLGLGRASPLFLRRGYQTERGVYGYRPRKPESREPEGGLARPPVDHGLARLVTVYCEHGHKAAKINPLFTGQALQENVPEIQALVQTLQGPFNTTGLLNMGKEEASLEEVVAYLNQIYCGQISIETSQLQSQEEKDWFAKRFEELKKEAFTTEERKHLSKLMLESQEFDHFLATKFATVKRYGGEGAESMMGFFYELLKMAAYSGVTDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENISAVGDVLSHLTSSVDLDFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSLDSSAQPGDKVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRAAQLAFEYQRQFRKDVIVDLLCYRQWGHNELDEPFFTNPGMYQIIRARKSIPDMYAEYLMANGLTTQEEVSEIKASYYVKLNGHLTHAAHYRPPATSLQAHWQGLVQPEACITSWNTGVPLDLLQFIGKKSVEVPEEFQIHSHLLKMHVQSRVEKVMDGTKLDWATAEALALGSLLAEGFNVRLSGQDVGRGTFSQRHAMVVCQKTDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPNLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVVLLPHGYDGAGPEHSSCRIERFLQMCDSTEEGVDGDTVNMCVAHPTTPAQYFHLLRRQMIRNFRKPLILVSPKTLLRLPAAVSTLQEMAPGTTFKPVIGDSSVDPKKVKSLVFCCGKHFYALMKQRESLEARKHDFAIIRIEELCPFPLDSLQQEMSKYKHVRDVIWSQEEPQNMGPWFFVSPRFEKQLACKLRLVSRPALPVPAVGIGTIHLQQHEEILTKTFNP", "length": 921, "header": "tr|A0A3Q1M6S6-1|E1BFI2_BOVIN Computationally mapped isoform of 2-oxoadipate dehydrogenase complex component E1 OS=Bos taurus OX=9913 GN=DHTKD1 PE=1 SV=1 CANONICAL=E1BFI2-1" }, "locus": { "chromosome": "13", "start_pos": 12281625, "end_pos": 12237918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079686.1", "url": "https://www.ensembl.org/id/ENSBTAT00000079686.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069454.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069454.1" } ] } }, { "isoform_ac": "A0A3Q1N7S2-1", "url": "https://www.uniprot.org/uniprotkb/E1BFI2/entry#A0A3Q1N7S2-1", "sequence": { "sequence": "MAWVAVAAARLGLGRASPLFLRRGYQTERGVYGYRPRKPESREPEGGLARPPVDHGLARLVTVYCEHGHKAAKINPLFTGQALQENVPEIQALVQTLQGPFNTTGLLNMGKEEASLEEVVAYLNQIYCGQISIETSQLQSQEEKDWFAKRFEELKKEAFTTEERKHLSKLMLESQEFDHFLATKFATVKRYGGEGAESMMGFFYELLKMAAYSGVTDVIIGMPHRGRLNLLTGLLQFPPEVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRAAQLAFEYQRQFRKDVIVDLLCYRQWGHNELDEPFFTNPGMYQIIRARKSIPDMYAEYLMANGLTTQEEVSEIKASYYVKLNGHLTHAAHYRPPATSLQAHWQGLVQPEACITSWNTGVPLDLLQFIGKKSVEVPEEFQIHSHLLKMHVQSRVEKVMDGTKLDWATAEALALGSLLAEGFNVRLSGQDVGRGTFSQRHAMVVCQKTDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPNLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVVLLPHGYDGAGPEHSSCRIERFLQMCDSTEEGVDGDTVNMCVAHPTTPAQYFHLLRRQMIRNFRKPLILVSPKTLLRLPAAVSTLQEMAPGTTFKPVIGDSSVDPKKVKSLVFCCGKHFYALMKQRESLEARKHDFAIIRIEELCPFPLDSLQQEMSKYKHVRDVIWSQEEPQNMGPWFFVSPRFEKQLACKLRLVSRPALPVPAVGIGTIHLQQHEEILTKTFNP", "length": 831, "header": "tr|A0A3Q1N7S2-1|E1BFI2_BOVIN Computationally mapped isoform of 2-oxoadipate dehydrogenase complex component E1 OS=Bos taurus OX=9913 GN=DHTKD1 PE=1 SV=1 CANONICAL=E1BFI2-1" }, "locus": { "chromosome": "13", "start_pos": 12281625, "end_pos": 12237918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070859.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070859.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066881.1", "url": "https://www.ensembl.org/id/ENSBTAP00000066881.1" } ] } }, { "isoform_ac": "A0A3Q1NLM6-1", "url": "https://www.uniprot.org/uniprotkb/E1BFI2/entry#A0A3Q1NLM6-1", "sequence": { "sequence": "MAWVAVAAARLGLGRASPLFLRRGYQTERGVYGYRPRKPESREPEGGLARPPVDHGLARLVTVYCEHGHKAAKINPLFTGQALQENVPEIQALVQTLQGPFNTTGLLNMGKEEASLEEVVAYLNQIYCGQISIETSQLQSQEEKDWFAKRFEELKKEAFTTEERKHLSKLMLESQEFDHFLATKFATVKRYGGEGAESMMGFFYELLKMAAYSGVTDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENISAVGDVLSHLTSSVDLDFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSLDSSAQPGDKVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRAAQLAFEYQRQFRKDVIVDLLCYRQWGHNELDEPFFTNPGMYQIIRARKSIPDMYAEYLMANGLTTQEEVSEIKASYYVKLNGHLTHAAHYRPPATSLQAHWQGLVQPEACITSWNTGVPLDLLQFIGKKSVEVPEEFQIHSHLLKMHVQSRVEKVMDGTKLDWATAEALALGSLLAEGFNVRLSGQDVGRGTFSQRHAMVVCQKTDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPNLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVVLLPHGYDGAGPEHSSCRIERFLQAAVSTLQEMAPGTTFKPVIGDSSVDPKKVKSLVFCCGKHFYALMKQRESLEARKHDFAIIRIEELCPFPLDSLQQEMSKYKHVRDVIWSQEEPQNMGPWFFVSPRFEKQLACKLRLVSRPALPVPAVGIGTIHLQQHEEILTKTFNP", "length": 866, "header": "tr|A0A3Q1NLM6-1|E1BFI2_BOVIN Computationally mapped isoform of 2-oxoadipate dehydrogenase complex component E1 OS=Bos taurus OX=9913 GN=DHTKD1 PE=1 SV=1 CANONICAL=E1BFI2-1" }, "locus": { "chromosome": "13", "start_pos": 12281625, "end_pos": 12237918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078440.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078440.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073346.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073346.1" } ] } }, { "isoform_ac": "E1BFI2-1", "url": "https://www.uniprot.org/uniprotkb/E1BFI2/entry#E1BFI2-1", "sequence": { "sequence": "MAWVAVAAARLGLGRASPLFLRRGYQTERGVYGYRPRKPESREPEGGLARPPGLLNMGKEEASLEEVVAYLNQIYCGQISIETSQLQSQEEKDWFAKRFEELKKEAFTTEERKHLSKLMLESQEFDHFLATKFATVKRYGGEGAESMMGFFYELLKMAAYSGVTDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENISAVGDVLSHLTSSVDLDFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSLDSSAQPGDKVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRAAQLAFEYQRQFRKDVIVDLLCYRQWGHNELDEPFFTNPGMYQIIRARKSIPDMYAEYLMANGLTTQEEVSEIKASYYVKLNGHLTHAAHYRPPATSLQAHWQGLVQPEACITSWNTGVPLDLLQFIGKKSVEVPEEFQIHSHLLKMHVQSRVEKVMDGTKLDWATAEALALGSLLAEGFNVRLSGQDVGRGTFSQRHAMVVCQKTDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPNLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVVLLPHGYDGAGPEHSSCRIERFLQMCDSTEEGVDGDTVNMCVAHPTTPAQYFHLLRRQMIRNFRKPLILVSPKTLLRLPAAVSTLQEMAPGTTFKPVIGDSSVDPKKVKSLVFCCGKHFYALMKQRESLEARKHDFAIIRIEELCPFPLDSLQQEMSKYKHVRDVIWSQEEPQNMGPWFFVSPRFEKQLACKLRLVSRPALPVPAVGIGTIHLQQHEEILTKTFNP", "length": 869, "header": "tr|E1BFI2-1|E1BFI2_BOVIN Isoform 1 of 2-oxoadipate dehydrogenase complex component E1 OS=Bos taurus OX=9913 GN=DHTKD1 PE=1 SV=3 CANONICAL=E1BFI2-1" }, "locus": { "chromosome": "13", "start_pos": 12281625, "end_pos": 12237918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000364.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000364.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000364.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000364.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:517113", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517113", "resource": "KEGG Pathway" }, { "id": "R-BTA-9858328", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9858328", "resource": "Reactome", "description": "OADH complex synthesizes glutaryl-CoA from 2-OA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M9M1-1", "protein_name": "2-oxoadipate dehydrogenase complex component E1", "gene_name": "Dhtkd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASATMAAARRGLCLSVSLLRRGYQTERGVYGYRPRKAESSEPRGDHARLSVDHGLARLVTVYCEHGHKAAQINPLFPGQALLDTVPEIQALVQTLQGPFTTTGLLNMGKEEASLEEVLAYLNHIYCGPISIETTQLQSQEEKDWFARRFEELKKETFTTEERKQLAKLLLESQEFDHFLATKFATVKRYGGEGAESMMGFFHELLKSSAYGGITDIIIGMPHRGRLNLLTGLLQLPPELMFRKMRGLSEFPENVSATGDVLSHLTSSVDLDFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSREDGDYSLHSSAQPGDKVICLQVHGDASFCGQGIVLETFTLSNLPHFRIGGSIHLIVNNQLGYTTPAERGRSSLYSSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIVDLLCYRQWGHNELDEPFFTNPVMYKIIRARKSIPDTYAEHLIASGLMTQEEVSDIKSSYYTKLNDHLTNVAHYSPPATNLQAHWQGLVQPEAHITTWDTGVPLELLRFIGVKSVEVPEELQLHNHLLKMYVQSRMEKVKSGTDLDWATAETLALGSLLAQGFNVRLSGQDVGRGTFSQRHAMVVCQNTDNAYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDSDTVNMFVVHPTTPAQYFHLLRRQMIRNFRKPLIIASPKVLLRYPAAVSTLQEMAPGTAFKPVIGDSSVDPKNVKTLIFCCGKHFYALLKQRESLGTKKHDFAIIRIEELCPFPLDSLQQEMSKYKHVKDIIWSQEEPQNMGPWFFVSPRFEKQLACKLRLVSRPPLPAPAVGIGTVHQQQHEDILTKTFAS", "length": 920 }, "evidence": [ { "id": "E1BFI2", "url": "https://omabrowser.org/oma/group/E1BFI2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XQ19-1", "protein_name": "2-oxoadipate dehydrogenase complex component E1", "gene_name": "DHTKD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAASTARCALWRWPWRAGLRRWYRTERGVYGYKPRKAAGESSAEPRDAGASGKAVDHALARLITAYSEHGHKAAKINPLFAGQAVMNVVPEIQELTEVLQGPLITTGLLNMGKEEASVEDVLAYLDHVYCGHISIETSQLPTLEERKWFTKRFEELKQEAFTTEEKKHLCKLMLESQEFDRFLATKFATVKRYGGEGAESMMGFFHELFKMCAYSGVTDIILGMPHRGRLNLLTGLLQLPPELMFRKMRGLSEFPENSAAIGDVLSHLTSSVDLDFGSHRPVHVTLLPNPSHLEAINPVAVGKTRGRQQSLLDGDYSPESSAQPGDKVICLQVHGDGAFSGQGIVPETLTLSNLPHFRVGGSIHLIVNNQLGYTTPPERGRSSLYCSDIGKIVGCAVIHVNGDDPEEVVRATRLAVEYQRHFRRDVIVDLLCYRQWGHNELDEPFFTNPSMYKIIRSRKSIPDTYAEHLVAAGLMTDVEVSEIKTTYYSKLNDHLANMTLYSPPPTNLQAHWKGLAEPSAKITTWDTGMPIPLLQFIGVKSVEVPEELQMHSHLLKTYAQSRVQKMEEGKKLDWATAETLAFGSLLSQGFNIRLSGQDVGRGTFSQRHAMLVCQETDDTYIPLNHMSPDQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPIWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPEHSSCRMERFLQMCDSSEEGVDGDRVNMSVVHPTTPAQYFHLLRRQMVRNFRKPLIVASPKVLLRLPAAASSFEEMAPRTTFKPVIGDSSVDPKSVTHVVFCSGKHYYALVKQRETLGEKQHNTAVIRLEELCPFPLEALQQELSKYSHAKVFTWSQEEPQNMGPWSFVSPRFEKQLGVKLRLVSRPPLPAPAVGIGTLHHQQQEDILTSTFI", "length": 922 }, "evidence": [ { "id": "E1BFI2", "url": "https://omabrowser.org/oma/group/E1BFI2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2ATU0-1", "protein_name": "2-oxoadipate dehydrogenase complex component E1", "gene_name": "Dhtkd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASAATVAAAGRALRRAVLLLRRGYQTERGVYGYRPRKAKSGEPRGDRARPSVDHGLARLVTVYCEHGHKAAQINPLFPGQALLDTVPEIQALVRTLQGPFTTTGLLNLGKEAASLEEVLAYLNHIYCGPISIETAQLQSQEERDWFARRFEELKKETFTTEERKYLSKLLLESQEFDHFLATKFATVKRYGGEGAESMMGFFHELLKLSAYGGITDIIIGMPHRGRLNLLTGLLQLPPELMFRKMRGLSEFPENVATIGDVLSHLTSSVDLDFGAHQPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSREDGDYSPNGSAQPGDKVICLQVHGDASFCGQGIVLETFTLSNLPHFRIGGSIHLIVNNQLGYTTPAERGRSSLYSSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIVDLLCYRQWGHNELDEPFFTNPVMYKIIRARKSIPDTYAEHLIASGLMTQEEVSDIKTSYYTKLNDHLANVAHYSPPATNLQARWQGLVQPEACVTTWDTGVPLELLRFIGVKSVEVPEELQVHSHLLKMYVQSRMEKVKNGSGLDWATAETLALGSLLAQGFNVRLSGQDVGRGTFSQRHAMVVCQDTDDAYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPTLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGLVILLPHGYDGAGPEHSSCRIERFLQMCDSAEEGVDSDTVNMFVVHPTTPAQYFHLLRRQMIRNFRKPLIVASPKMLLRYPAAVSTLEEMAPGTAFKPVIGDSSVDPKNVKTLIFCSGKHFYALLKQRESLGTKKHDFAIIRLEELCPFPLDALQQEMSKYKHVRDVIWSQEEPQNMGPWSFVSPRFEKQLACRLRLVSRPPLPAPAVGIGTVHQQQHEDILSKTFTQ", "length": 921 }, "evidence": [ { "id": "E1BFI2", "url": "https://omabrowser.org/oma/group/E1BFI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4KLP0-1", "protein_name": "2-oxoadipate dehydrogenase complex component E1", "gene_name": "Dhtkd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASATVAAAGRALRRAVPLLRRSYQTERGVYGYRPRKAGSGEPRGDRARPSVDHGLARLVTVYCEHGHKAAQINPLFPGQALLDTVPEIQALVQTLQGPFTTTGLLNMGKEEASLEEVLAYLNHIYCGPISIETAQLQSQEEKDWFARRFEELKKETFTTEERKHLSKLLLESQEFDHFLATKFATVKRYGGEGAESMMGFFHELLKLSAYGGITDIIIGMPHRGRLNLLTGLLQLPPELMFRKMRGLSEFPENVAAIGDVLSHLTSSVDLDFGAHRPLHVTMLPNPSHLEAINPVAVGKTRGRQQSQEDGDYSPNGSAQPGDKVICLQVHGDASFCGQGIVLETFTLSNLPHFRIGGSIHLIVNNQLGYTTPAERGRSSLYSSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFFTNPVMYKIIRARKSIPDTYAEHLIASGLMTQEEVSDIKASYYAKLNGHLANVAHYSPPAPHLQARWQGLVQPAACVTTWDTGVPLELLRFVGVKSVEVPEELQLHSHLLKMYVQSRMEKVKNGTNLDWATAETLALGSLLAQGFNVRLSGQDVGRGTFSQRHAMVVCQNTDDVYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGLVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDSDTVNMFVVHPTTPAQYFHLLRRQMMRNFRKPLIVASPKMLLRYPVAVSTLEEMAPGTAFKPVIGDSSVDPKNVKTLIFCSGKHFYALLKQRESLGAKKRDFAIIRLEELCPFPLDSLQQEMGKYKHVQDIIWSQEEPQNMGPWSFVYPRFEKQLACKLRLVSRPPLPAPAVGIGTVHQQQHEAILFKTFTS", "length": 920 }, "evidence": [ { "id": "E1BFI2", "url": "https://omabrowser.org/oma/group/E1BFI2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54VG0-1", "protein_name": "Probable 2-oxoadipate dehydrogenase complex component E1 homolog", "gene_name": "odhA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIGLRSISKNKQTINSISKSFYCTSSPSSSSVKLSVTRLIDGYRAHGHLAANIDPLARMERIRSQLLDLDRYNLVKGQSIPSTIDLINQDLTNLDQVVSFLENAYCNDVTAQFDHIESIEEKAWLYEKFEQLQHQNPSKSEKINILKNLIKSEIFDQFMQKKFPTFKRYGLEGNESMMVSCDSIFRESAKNQLKNVVIGMPHRGRLNLLVQMCNYPAKDFFWKVKGNSEFSEGILGVGDVTSHIAVSTDLQFNNNKESVHVSLIHNPSHLEAVDPVAAGKTRAKQFYEKNEGGSESLCLMLHGDAAVAGQGVVTETLQLSQLSGFNIGGCVHVIVNNQIGFTTVPTNGRSNRYSSDIGKFIGAPIIVVNSQSPEQVEKVSRLAVEYRQKFKKDIIIDLIGWRKFGHNEVDEPSFTQPTMYQNIRKRQSIPQKYATQIISQGIFSEQELLEFTQKEQAILEEQFQLSTPENFKYSPMDHLQGKWSGLIQSKHIADDSKLDTGYSVEELSEIANDSVKVPSDFQVHQRLLRSFSNARLEKLKQNQADWATAESMAVGSLMKQGYNVRISGQDVGRGTFSQRHFNLTEQNSDRIYQPLNNMGAKGELDVVNSNLSEFAVLCYEYGYSLESPDTLPIWEAQFGDFINGAQIAIDQFVTSGESKWLRQSGIVILLPHGFDGAGPEHSSCRIERFLQLSDTEAVNVKDDTLINQETNFYFINPSTPANYFHALRRQMIRNYRKPLIVAGPKVLLRHPNCFSTLNEMAPGTHFQTVLSDPDTINNASTIKRVIFCSGKVFYDLQEERKAKNFNDVAIIRLEQIAPFPYQRIQEEINRYSNATKFAWVQEEQQNGGCWSFVEPRFKQRYPQTSQIKYIGRPPLAASAIGISSIHKKEVSQLLIDAFNF", "length": 900 }, "evidence": [ { "id": "E1BFI2", "url": "https://omabrowser.org/oma/group/E1BFI2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q96HY7-1", "protein_name": "2-oxoadipate dehydrogenase complex component E1", "gene_name": "DHTKD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASATAAAARRGLGRALPLFWRGYQTERGVYGYRPRKPESREPQGALERPPVDHGLARLVTVYCEHGHKAAKINPLFTGQALLENVPEIQALVQTLQGPFHTAGLLNMGKEEASLEEVLVYLNQIYCGQISIETSQLQSQDEKDWFAKRFEELQKETFTTEERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHELLKMSAYSGITDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVDLYFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSPDNSAQPGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYKIIRARKSIPDTYAEHLIAGGLMTQEEVSEIKSSYYAKLNDHLNNMAHYRPPALNLQAHWQGLAQPEAQITTWSTGVPLDLLRFVGMKSVEVPRELQMHSHLLKTHVQSRMEKMMDGIKLDWATAEALALGSLLAQGFNVRLSGQDVGRGTFSQRHAIVVCQETDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDTVNMFVVHPTTPAQYFHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGDSSVDPKKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIRVEELCPFPLDSLQQEMSKYKHVKDHIWSQEEPQNMGPWSFVSPRFEKQLACKLRLVGRPPLPVPAVGIGTVHLHQHEDILAKTFA", "length": 919 }, "evidence": [ { "id": "E1BFI2", "url": "https://omabrowser.org/oma/group/E1BFI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VA02-1", "protein_name": "Probable 2-oxoadipate dehydrogenase complex component E1 homolog", "gene_name": "Oadh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRYLALSEAGIAKLPRPQSRCYHSEKGVWGYKPIAQREFQVAEDVRASRNSQANVYRFVEAFRQHGHKLAAVNPISIRTSQQELQELSPAFYGLQTQEPVRTDGLLSGPQVAHNVAQLEQLLKDIYCGRSTSAEFSYVEDIEEREWLARNFETLDQQQLGKSERCEIAELLIKSQAWDNFMALKFPTVKRYGGEGAESMLAFFWQLLRDSVQANIEHVVLAMPHRGRTPLQAALLNMRPAKVFRKLSGASEFSEDIEAMSDVISHFHVSEQLKILGKKLSFSMVRNPSHLEAANPVAMGKTRSKQQARGEGAFGDGSQPFGEHVLNVILHGDAAFAGQGINQECLNMAYVPHFEVGGSLHLIVNNQVGFTTPGDRGRSTAYTSDLAKSIQAPVFHVNGDDPEALARVTSLAFRYQREFRKDIFIDLNCFRRWGHNELDDPTFTNPLVYKIVHQRESVPDLYAQQLAKEQVLSESKAKEMRDEYMKYLGEELALAPAYQPPPSYFEKQWTNFQLAPSKELTYWDTGLDYSLLHYIGQQSVTFPEDFNIHPHLLKTHVNARLKKLENGVKIDWSTAEALAIGSLMYQGHNVRISGEDVGRGTFSHRHAMLVDQQTNEMFIPLNSMEGGNGGKLELAHSILSEEAVLGFEYGMAIDNPNNLIIWEAQFGDFANGAQIIIDTFIVSGETKWMESNALVMLLPHGYDGAASEHSSCRIERFLQLCDSKETSADGDSVNVHIVNPTTPAQYYHVLRRQLARNFRKPLVVVAPKTLLRLPAATSTHEDFQPGTLFHNVLGDTIAKPEQVRKVILCSGKHYYTLAEEREKRQAYDTAILRLESLCPFPIQELQAQLAQYGNVQSFVWSQEEHRNMGAWTFVRPRFENLIGQQLHYCGRCEAPTPATGIGKVHKREVDEIVAAPFEL", "length": 919 }, "evidence": [ { "id": "E1BFI2", "url": "https://omabrowser.org/oma/group/E1BFI2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BFI2", "url": "https://www.uniprot.org/uniprotkb/E1BFI2" } ], "pmid": "" }, { "name": "oxoadipate dehydrogenase complex", "id": "GO:0160167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160167", "evidence": [ { "database": "UniProtKB", "id": "E1BFI2", "url": "https://www.uniprot.org/uniprotkb/E1BFI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "E1BFI2", "url": "https://www.uniprot.org/uniprotkb/E1BFI2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "thiamine pyrophosphate binding", "id": "GO:0030976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030976", "evidence": [ { "database": "UniProtKB", "id": "E1BFI2", "url": "https://www.uniprot.org/uniprotkb/E1BFI2" } ], "pmid": "" }, { "name": "2-oxoadipate dehydrogenase activity", "id": "GO:0160166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160166", "evidence": [ { "database": "UniProtKB", "id": "E1BFI2", "url": "https://www.uniprot.org/uniprotkb/E1BFI2" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor", "id": "GO:0016624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016624", "evidence": [ { "database": "UniProtKB", "id": "E1BFI2", "url": "https://www.uniprot.org/uniprotkb/E1BFI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "69576", "name": "", "equation": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 2-oxoadipate + H(+) = N(6)-[(R)-S(8)-glutaryldihydrolipoyl]-L-lysyl-[protein] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "69576", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69576" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFI2" }, { "id": "SM00861", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00861" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transketolase-like pyrimidine-binding", "eco_id": "ECO_0000259", "start_pos": 518, "end_pos": 721, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFA7-1", "uniprot_ac": "E1BFA7", "uniprot_id": "E1BFA7_BOVIN", "mass": { "chemical_mass": 92590.0, "monoisotopic_mass": 92590.0 }, "refseq": { "ac": "XP_024834731", "name": "kinesin-like protein KIFC3 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834731" }, "gene_names": [ { "name": "KIFC3", "type": "recommended", "evidence": [ { "id": "E1BFA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ] }, { "name": "KIFC3", "type": "synonym", "evidence": [ { "id": "XP_024834731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834731" } ] } ], "protein_names": [ { "name": "Kinesin-like protein", "type": "recommended", "evidence": [ { "id": "E1BFA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFA7/entry#names_and_taxonomy" } ] }, { "name": "kinesin-like protein KIFC3 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_024834731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834731" } ] } ], "function": [ { "annotation": "Minus-end microtubule-dependent motor protein. Involved in apically targeted transport. Required for zonula adherens maintenance.", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7#function" }, { "database": "UniProtKB", "id": "ARBA00060102", "url": "https://www.uniprot.org/uniprotkb/ARBA00060102#function" }, { "database": "UniProtKB", "id": "A0A3Q1NNJ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNJ6#function" }, { "database": "UniProtKB", "id": "A0AAA9SGB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGB5#function" }, { "database": "UniProtKB", "id": "A0A3Q1N6U5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6U5#function" }, { "database": "UniProtKB", "id": "A0AAA9TSJ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KIFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFA7", "locus": { "chromosome": "18", "start_pos": 25721853, "end_pos": 25769858, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007181", "url": "https://www.ensembl.org/id/ENSBTAG00000007181" } ] } } ], "crossref": [ { "id": "E1BFA7", "url": "https://alphafold.ebi.ac.uk/entry/E1BFA7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007181", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007181", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01366", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01366", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539231", "url": "https://www.ncbi.nlm.nih.gov/gene/539231", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RHDMQKC", "url": "https://omabrowser.org/oma/group/RHDMQKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NNJ6", "url": "https://www.orthodb.org/?gene=A0A3Q1NNJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47972:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47972:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024834731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834731", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N6U5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N6U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NNJ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NNJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGB5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSJ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFA7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPSRRTWNLGATPSLRGLWRVGRAGEPDPGMARPAPASPAARPFPHTGPGRLRTGRGKDSPAGGDEDSGTRSAARPALAQCRALSVDWAGPGSPHRLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRAKPAAPCTGCEHSQESAQLRDRLSQLQLEVAENKGLLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPIKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTAQLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALKSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDPDDDSIIHLLHKGKPVSFELDKVFSSQASQQDVFQEVQALITSCIDGFNVCIFAYGQTGAGKTYTMEGTPENPGINQRALRLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGQEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVEDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGSRRTELGSWSSQEHLEWESACQTPQPSARAHSAPGSGTTSRPGSIRRKLQPSGKSRPLPV", "length": 831, "header": "tr|E1BFA7-1|E1BFA7_BOVIN Isoform 1 of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIFC3 PE=3 SV=4 CANONICAL=E1BFA7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N6U5-1", "url": "https://www.uniprot.org/uniprotkb/E1BFA7/entry#A0A3Q1N6U5-1", "sequence": { "sequence": "MSLLIKEDPRQVPGTQQAARCPEEATKPRRAMVPSRRTWNLGATPSLRGLWRVGRAGEPDPGMARPAPASPAARPFPHTGPGRLRTGRGKDSPAGGDEDSGTRSAARPALAQCRALSVDWAGPGSPHRLYLTLQQALQDKGCESKSQGTKEEKPLKRQAPAPRRDREAQEAGGAMNVEKTGGRPFGSGRCSSLSGSPSAAPVVHRMVEAMSQLREEKAQLQEELVALRERLAVRDSEQQAASTQLQNQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRAKPAAPCTGCEHSQESAQLRDRLSQLQLEVAENKGLLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPIKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTAQLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALKSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDPDDDSIIHLLHKGKPVSFELDKVFSSQASQQDVFQEVQALITSCIDGFNVCIFAYGQTGAGKTYTMEGTPENPGINQRALRLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGQEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVEDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGSRRTELGSWSSQEHLEWESACQTPQPSARAHSAPGSGTTSRPGSIRRKLQPSA", "length": 969, "header": "tr|A0A3Q1N6U5-1|E1BFA7_BOVIN Computationally mapped isoform of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIFC3 PE=3 SV=2 CANONICAL=E1BFA7-1" }, "locus": { "chromosome": "18", "start_pos": 25753197, "end_pos": 25723103, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078698.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078698.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066287.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066287.2" } ] } }, { "isoform_ac": "A0A3Q1NNJ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BFA7/entry#A0A3Q1NNJ6-1", "sequence": { "sequence": "MVPSRRTWNLGATPSLRGLWRVGRAGEPDPGMARPAPASPAARPFPHTGPGRLRTGRGKDSPAGGDEDSGTRSAARPALAQCRALSVDWAGPGSPHRLYLTLQQALQDKGCESKSQGTKEEKPLKRQAPAPRRDREAQEAGGAMNVEKTGGRPFGSGRCSSLSGSPSAAPVVHRMVEAMSQLREEKAQLQEELVALRERLAVRDSEQQAASTQLQNQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRAKPAAPCTGCEHSQESAQLRDRLSQLQLEVAENKGLLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPIKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTAQLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALKSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDPDDDSIIHLLHKGKPVSFELDKVFSSQASQQDVFQEVQALITSCIDGFNVCIFAYGQTGAGKTYTMEGTPENPGINQRALRLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGQEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVEDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGSRRTELGSWSSQEHLEWESACQTPQPSARAHSAPGSGTTSRPGSIRRKLQPSGKSRPLPV", "length": 945, "header": "tr|A0A3Q1NNJ6-1|E1BFA7_BOVIN Computationally mapped isoform of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIFC3 PE=3 SV=1 CANONICAL=E1BFA7-1" }, "locus": { "chromosome": "18", "start_pos": 25752545, "end_pos": 25722857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070950.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070950.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074405.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074405.1" } ] } }, { "isoform_ac": "A0AAA9SGB5-1", "url": "https://www.uniprot.org/uniprotkb/E1BFA7/entry#A0AAA9SGB5-1", "sequence": { "sequence": "THKVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRAKPAAPCTGCEHSQESAQLRDRLSQLQLEVAENKGLLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPIKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTAQLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALKSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDPDDDSIIHLLHKGKPVSFELDKVFSSQASQQDVFQEVQALITSCIDGFNVCIFAYGQTGAGKTYTMEGTPENPGINQRALRLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGQEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVEDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGSRRTELGSWSSQEHLEWESACQTPQPSARAHSAPGSGTTSRPGSIRRKLQPSA", "length": 724, "header": "tr|A0AAA9SGB5-1|E1BFA7_BOVIN Computationally mapped isoform of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIFC3 PE=3 SV=1 CANONICAL=E1BFA7-1" }, "locus": { "chromosome": "18", "start_pos": 25736481, "end_pos": 25723103, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089570.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089570.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085206.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085206.1" } ] } }, { "isoform_ac": "A0AAA9TSJ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFA7/entry#A0AAA9TSJ8-1", "sequence": { "sequence": "MYGFQAARCPEEATKPRRAMVPSRRTWNLGATPSLRGLWRVGRAGEPDPGMARPAPASPAARPFPHTGPGRLRTGRGKDSPAGGDEDSGTRSAARPALAQCRALSVDWAGPGSPHRLYLTLQQALQDKGCESKSQGTKEEKPLKRQAPAPRRDREAQEAGGAMNVEKTGGRPFGSGRCSSLSGSPSAAPVVHRMVEAMSQLREEKAQLQEELVALRERLAVRDSEQQAASTQLQNQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRAKPAAPCTGCEHSQESAQLRDRLSQLQLEVAENKGLLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPIKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTAQLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALKSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDPDDDSIIHLLHKGKPVSFELDKVFSSQASQQDVFQEVQALITSCIDGFNVCIFAYGQTGAGKTYTMEGTPENPGINQRALRLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGQEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVEDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGSRRTELGSWSSQEHLEWESACQTPQPSARAHSAPGSGTTSRPGSIRRKLQPSA", "length": 957, "header": "tr|A0AAA9TSJ8-1|E1BFA7_BOVIN Computationally mapped isoform of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIFC3 PE=3 SV=1 CANONICAL=E1BFA7-1" }, "locus": { "chromosome": "18", "start_pos": 25769627, "end_pos": 25723103, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102643.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102643.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100333.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100333.1" } ] } }, { "isoform_ac": "E1BFA7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFA7/entry#E1BFA7-1", "sequence": { "sequence": "MVPSRRTWNLGATPSLRGLWRVGRAGEPDPGMARPAPASPAARPFPHTGPGRLRTGRGKDSPAGGDEDSGTRSAARPALAQCRALSVDWAGPGSPHRLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRAKPAAPCTGCEHSQESAQLRDRLSQLQLEVAENKGLLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPIKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTAQLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALKSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDPDDDSIIHLLHKGKPVSFELDKVFSSQASQQDVFQEVQALITSCIDGFNVCIFAYGQTGAGKTYTMEGTPENPGINQRALRLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGQEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVEDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGSRRTELGSWSSQEHLEWESACQTPQPSARAHSAPGSGTTSRPGSIRRKLQPSGKSRPLPV", "length": 831, "header": "tr|E1BFA7-1|E1BFA7_BOVIN Isoform 1 of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIFC3 PE=3 SV=4 CANONICAL=E1BFA7-1" }, "locus": { "chromosome": "18", "start_pos": 25752545, "end_pos": 25722857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032447.6", "url": "https://www.ensembl.org/id/ENSBTAT00000032447.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032379.6", "url": "https://www.ensembl.org/id/ENSBTAP00000032379.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 13, "start_aa": "Thr", "end_pos": 13, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr13", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZSI9-1", "protein_name": "Kinesin-like protein", "gene_name": "Kifc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWAELLFGEGTLAAFWRSRDKDEPEVETGITTQQNKPARHPEEVAEPRAMVPSRRTWNLGATPSLRGLWRVGRVQEPKPGMARPAPASPAARPFPHTGQGRLRTGRGKDTLPGGEEDSTSRSAARPSLAQCRALSVDWPGPRSPHRLYLTVQQALQDKGCESKSQGTKEDRLPKRQAPAPRRDREAPEAGGTMNVEKPGGRLLGIGRCSSLSGSPGPDPVVHRTVEAMSQLQEELVVLRERLALHDSDRQATTTQLQNQVENLKEKLISQAQEVSRLRSELGGTDVEKHRDRLMVENEQLRQELRRCEAELQELRAQPVVPCQGCEHSQESTQLRDRLSQLQLEVAENKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLKAQSPPVKYVIKTVEVESSKTKQALSESQTRNQHLQEQVAMQRQVLKEMEQQLQNSHQLTIQLRAQIAMYEAELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDPDDDSIIHLLHKGKPVSFELDKVFSPWASQQDVFQEVQALITSCIDGFNVCIFAYGQTGAGKTYTMEGTPENPGINQRALQLLFSEVQEKASDWQYNITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGYNNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGNRLREAQHINRSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGSRRTELGSWSSQEHLEWEPACQTPQPTARAHSAPGSGTSSRPGSIRRKLQPSGKLRPVPV", "length": 988 }, "evidence": [ { "id": "E1BFA7", "url": "https://omabrowser.org/oma/group/E1BFA7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZD66-1", "protein_name": "Kinesin-like protein", "gene_name": "KIFC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHALGALAALSVLGWTKGSKRQSVALQSTGGLPGARRWAAGPGPQAQVLLERGQQPALVRTTEEPPASPCEPAVPGQAARTMSLEKAGGRFCSGKRAGLPAQRPFPVIQKVVASMAHLQEEKLRLQEELLALQEKLAARESEEIAASVQLRGQVENLKANLREQAQEIGRLRSEMGGTDAEKHRDLLAAENERLRQEMKAREGELRELRRQQAACRDCTHLQESAGLQERLCQLQREAEEARAKLAELELEVQQKTNRLAEVELRLKDSLAERAQEEERLSRRLRDSQETIASLRAQPQQIKYVIKTVEVESAKAKQALCESQSRNQYLQEQVGMQRQVLKEMEQQLQSSQKTAAQLRAQIAMYETELERAHGQMLEEMQAMEDEKNRAIEEAFSRAQVEMKAVHENLAGVRTNLLTLQPALRTLTHDYNSLKRQVRDFPLLLQETLRSARAEIGQAIEEVNSTNRELLRKYRRELQLRKKCHNELVRLKGNIRVFGRVRPITKEDGEGPEAVSAVTFDADDDAVLHLLHKGKQVSFELDKVFPPQASQEEVFQEVQALVTSCIDGYNVCIFAYGQTGAGKTYTMEGTSANPGINQRALQLLFSEVRSKAADWDYAISVSVAEIYNEALRDLLGKEPQEKLEIKLCPDGSGQLYVPGLTEFSVQSVEDINKVFEFGHVNRVTECTNLNEHSSRSHALLIVTVRGLDRSTGLRTTGKLNLVDLAGSERVGRSGAEGSRLREAQYINRSLSALGDVIYALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMMVQVSPAEKNSSETLCSLKFAERVRSVELGPVSRKAELVSWPSQEQLEGDLPGSSGRGHASPSPGLPSGRSTSIRRKLQTSA", "length": 870 }, "evidence": [ { "id": "E1BFA7", "url": "https://omabrowser.org/oma/group/E1BFA7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O35231-1", "protein_name": "Kinesin-like protein KIFC3", "gene_name": "Kifc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVPSRRTWNLGATPSLRGLWRVGRVQEPKPGMARPAPASPAARPFPHTGQGRLRTGRGKDILPSGEEDSTSRTAARPSLAQCRALSVDWPGPRSPHRLYLTVQVENLKEKLISQAQEVSRLRSELGGTDAEKHRDRLMVENEQLRQELRRCEVELQELRAQPVVPCEGCEHSQESSQLRDKLSQLQLEVAENKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQTRNQHLQEQVAMQRQVLKEMEQQLQNSHQLTVQLRAQIAMYEAELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDPDDDSIIHLLHKGKPVSFELDKVFSPWASQQDVFQEVQALITSCIDGFNVCIFAYGQTGAGKTYTMEGTPENPGINQRALQLLFSEVQEKASDWQYNITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGYNNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGNRLREAQHINRSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLRFAERVRSVELGPGSRRTELGSWSSQEHLEWEPACQTPQPTARAHSAPGSGTSSRPGSIRRKLQPSA", "length": 824 }, "evidence": [ { "id": "E1BFA7", "url": "https://omabrowser.org/oma/group/E1BFA7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BVG8-3", "protein_name": "Kinesin-like protein KIFC3", "gene_name": "KIFC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPSGKSRPLPV", "length": 833 }, "evidence": [ { "id": "E1BFA7", "url": "https://omabrowser.org/oma/group/E1BFA7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "zonula adherens", "id": "GO:0005915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005915", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "zonula adherens maintenance", "id": "GO:0045218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045218", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "epithelial cell-cell adhesion", "id": "GO:0090136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090136", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" }, { "name": "microtubule-based process", "id": "GO:0007017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", "evidence": [ { "database": "UniProtKB", "id": "E1BFA7", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 696, "end_pos": 698, "annotation": "n_glycosylation_sequon" }, { "start_pos": 749, "end_pos": 751, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFA7" }, { "id": "PS50067", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinesin motor", "eco_id": "ECO_0000259", "start_pos": 443, "end_pos": 766, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 13 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 630, "end_pos": 632 }, { "start_pos": 696, "end_pos": 698 }, { "start_pos": 749, "end_pos": 751 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BES3-1", "uniprot_ac": "E1BES3", "uniprot_id": "E1BES3_BOVIN", "mass": { "chemical_mass": 147262.0, "monoisotopic_mass": 147262.0 }, "refseq": { "ac": "XP_024848740", "name": "limbin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024848740" }, "gene_names": [ { "name": "EVC2", "type": "recommended", "evidence": [ { "id": "E1BES3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BES3" } ] }, { "name": "EVC2", "type": "synonym", "evidence": [ { "id": "XP_024848740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024848740" } ] }, { "name": "LBN", "type": "synonym", "evidence": [ { "id": "XP_024848740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024848740" } ] } ], "protein_names": [ { "name": "EvC ciliary complex subunit 2", "type": "synonym", "evidence": [ { "id": "E1BES3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BES3/entry#names_and_taxonomy" } ] }, { "name": "limbin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024848740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024848740" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BES3", "url": "https://www.uniprot.org/uniprotkb/E1BES3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EVC2", "url": "https://www.uniprot.org/uniprotkb/E1BES3", "locus": { "chromosome": "6", "start_pos": 103662794, "end_pos": 103500498, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004277", "url": "https://www.ensembl.org/id/ENSBTAG00000004277" } ] } } ], "crossref": [ { "id": "ENSBTAG00000004277", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004277", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "280834", "url": "https://www.ncbi.nlm.nih.gov/gene/280834", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IFFAQIK", "url": "https://omabrowser.org/oma/group/IFFAQIK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BES3", "url": "https://www.orthodb.org/?gene=E1BES3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16795", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16795", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16795:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16795:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5632684", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5632684", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5635838", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5635838", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024848740", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024848740", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9THK4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BES3", "url": "https://www.uniprot.org/uniprotkb/E1BES3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BES3-1", "url": "https://www.uniprot.org/uniprotkb/E1BES3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTPRGPGRATWVLAGSLLAAALALPAESRNLGQLPAGQVPLQHPLGPQPLRDPHTVPGAGLERTAQDLPLGIWPSVENSHVTTPEEAPFGMKFSKEIEVFNPPLASSASSGPWVHSVFAFTHSWPRKTLFKRDSAVTHRLYGDISRDFQGTSENGVIFQKCAVVSVQSEWPSAHVRLFVNNTRTPTAANLSDLFLLDNITGLTIRESAGNQTSRGFQAFRKKFLQVGDSFSVSYTASLEARDVGSGDILLLPAQLSFQSSSPNRTQLKAPFTITAEEKITVLPNHGLHAAGFCVAFILSLVLTWAVLFFMVRYQCVKGSSLTRHQVQHHENKLEHSQFTSADGVNEDLALNDQMIDILSSEDPGSMLQALEELEIATLNRADSDLEACRTQISKDIIALLLKNLTSSGQLSPQVERRMGAVFKKQFLLLEKEIQEEYDRKMVALTAECDLETRKKTESQYQREMAAMEEAEEVLKRVSERSAVECSSLLRTLHGLEQEHLRRSLALQQEEDLAKAHRQLAIFQRNELHNIFFTQIKSAIFKGELKPEAAKMLLQDYSKIQESVEELMDFFQASKRYHLSKRFGHREYLVQNIQSSETRMQGLLSTASAQLTLLIQKHERAGYLDEDQMQVLLERAQTEVFSIKQKLDNDLKQEKKKLHQKLIIKRRREMLQKHKEQRREQLSIAEASGAAEDAGQYLGQWRGLMAEHSAALEELQERLDQAALDELRALTLSLSEKATEELRRLQNSGMTQELLKRGVPWLFLQQILEEHSRDLAARAERLEGEERDRGQEGVQSVRQRLKDDALEASTEEQAELRHWEHLIFTKLCSSAFSLSEEELLGMRQEVHGCFAQMDRSLALPKIRARVLLQRFQTAWREAEFLKLDQAMTAPELQPQSKARKPRSKSRSKIDLLKKCTEDKIQLFKEQAPEDLVEKVRGELLRERVQQLEAQEGLFAESLVSLQFQKAARMARTLWAYTALLSIQDLLLEELNSSETLTKSACMQILESHSPELQELERKLEDQLAHQEAAQLQRALDSWQQWAGEGPALLQEPEETDSERHVSAVLQRALSKGQKLLEYHQQSLREEQEDSVVLEDLLENMETDTFVTLYGQELRLASYLSKLTMLPGGTLRRLLTVALPAASQAELLAVLDSVGQKHQDHSVENDGSRVQADLGRRGKHQGWWQALESKLRGELINRGLEKMLWAQKRKESILKKTCPPLRERVIFSGKRSWPHLSLESTDELTPVPIVGAEAVDLLNTGEKLFIFRNPKEPEISLHVPPRKKKKNFLNAKKAAWALGLN", "length": 1300, "header": "tr|E1BES3-1|E1BES3_BOVIN Isoform 1 of EvC ciliary complex subunit 2 OS=Bos taurus OX=9913 GN=EVC2 PE=4 SV=3 CANONICAL=E1BES3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9THK4-1", "url": "https://www.uniprot.org/uniprotkb/E1BES3/entry#A0AAA9THK4-1", "sequence": { "sequence": "MLGGGGAGPGVRKLPQLRLHPPLVGSRDPGGRWIPRGARGGPRGCWRGACWPLHWRCPRSPETSASSPRGRFPSSTPWAHSLSGTPTRFPGRGLSGPPRTYPLGFGPVWKTLTLQLQYGDISRDFQGTSENGVIFQKCAVVSVQSEWPSAHVRLFVNNTRTPTAANLSDLFLLDNITGLTIRESAGNQTSRGFQAFRKKFLQVGDSFSVSYTASLEARDVGSGDILLLPAQLSFQSSSPNRTQLKAPFTITAEEKITVLPNHGLHAAGFCVAFILSLVLTWAVLFFMVRYQCVKGSSLTRHQVQHHENKLEHSQFTSADGVNEDLALNDQMIDILSSEDPGSMLQALEELEIATLNRADSDLEACRTQISKDIIALLLKNLTSSGQLSPQVERRMGAVFKKQFLLLEKEIQEEYDRKMVALTAECDLETRKKTESQYQREMAAMEEAEEVLKRVSERSAVECSSLLRTLHGLEQEHLRRSLALQQEEDLAKAHRQLAIFQRNELHNIFFTQIKSAIFKGELKPEAAKMLLQDYSKIQESVEELMDFFQASKRYHLSKRFGHREYLVQNIQSSETRMQGLLSTASAQLTLLIQKHERAGYLDEDQMQVLLERAQTEVFSIKQKLDNDLKQEKKKLHQKLIIKRRREMLQKHKEQRREQLSIAEASGAAEDAGQYLGQWRGLMAEHSAALEELQERLDQAALDELRALTLSLSEKATEELRRLQNSGMTQELLKRGVPWLFLQQILEEHSRDLAARAERLEGEERDRGQEGVQSVRQRLKDDALEASTEEQAELRHWEHLIFTKLCSSAFSLSEEELLGMRQEVHGCFAQMDRSLALPKIRARVLLQRFQTAWREAEFLKLDQAMTAPELQPQSKARKPRSKSRSKIDLLKKCTEDKIQLFKEQAPEDLVEKVRGELLRERVQQLEAQEGLFAESLVSLQFQKAARMARTLWAYTALLSIQDLLLEELNSSETLTKSACMQILESHSPELQELERKLEDQLAHQEAAQLQRALDSWQQWAGEGPALLQEPEETDSERHVSAVLQRALSKGQKLLEYHQQSLREEQEDSVVLEDLLENMETDTFVTLYGQELRLASYLSKLTMLPGGTLRRLLTVALPAASQAELLAVLDSVGQKHQDHSVENDGSRVQADLGRRGKHQGWWQALESKLRGELINRGLEKMLWAQKRKESILKKTCPPLRERVIFSGKRSWPHLSLESTDELTPVPIVGAEAVDLLNTGEKLFIFRNPKEPEISLHVPPRKKKKNFLNAKKAAWALGLN", "length": 1276, "header": "tr|A0AAA9THK4-1|E1BES3_BOVIN Computationally mapped isoform of EvC ciliary complex subunit 2 OS=Bos taurus OX=9913 GN=EVC2 PE=4 SV=1 CANONICAL=E1BES3-1" }, "locus": { "chromosome": "6", "start_pos": 103662342, "end_pos": 103500622, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128571.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128571.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095694.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095694.1" } ] } }, { "isoform_ac": "E1BES3-1", "url": "https://www.uniprot.org/uniprotkb/E1BES3/entry#E1BES3-1", "sequence": { "sequence": "MDTPRGPGRATWVLAGSLLAAALALPAESRNLGQLPAGQVPLQHPLGPQPLRDPHTVPGAGLERTAQDLPLGIWPSVENSHVTTPEEAPFGMKFSKEIEVFNPPLASSASSGPWVHSVFAFTHSWPRKTLFKRDSAVTHRLYGDISRDFQGTSENGVIFQKCAVVSVQSEWPSAHVRLFVNNTRTPTAANLSDLFLLDNITGLTIRESAGNQTSRGFQAFRKKFLQVGDSFSVSYTASLEARDVGSGDILLLPAQLSFQSSSPNRTQLKAPFTITAEEKITVLPNHGLHAAGFCVAFILSLVLTWAVLFFMVRYQCVKGSSLTRHQVQHHENKLEHSQFTSADGVNEDLALNDQMIDILSSEDPGSMLQALEELEIATLNRADSDLEACRTQISKDIIALLLKNLTSSGQLSPQVERRMGAVFKKQFLLLEKEIQEEYDRKMVALTAECDLETRKKTESQYQREMAAMEEAEEVLKRVSERSAVECSSLLRTLHGLEQEHLRRSLALQQEEDLAKAHRQLAIFQRNELHNIFFTQIKSAIFKGELKPEAAKMLLQDYSKIQESVEELMDFFQASKRYHLSKRFGHREYLVQNIQSSETRMQGLLSTASAQLTLLIQKHERAGYLDEDQMQVLLERAQTEVFSIKQKLDNDLKQEKKKLHQKLIIKRRREMLQKHKEQRREQLSIAEASGAAEDAGQYLGQWRGLMAEHSAALEELQERLDQAALDELRALTLSLSEKATEELRRLQNSGMTQELLKRGVPWLFLQQILEEHSRDLAARAERLEGEERDRGQEGVQSVRQRLKDDALEASTEEQAELRHWEHLIFTKLCSSAFSLSEEELLGMRQEVHGCFAQMDRSLALPKIRARVLLQRFQTAWREAEFLKLDQAMTAPELQPQSKARKPRSKSRSKIDLLKKCTEDKIQLFKEQAPEDLVEKVRGELLRERVQQLEAQEGLFAESLVSLQFQKAARMARTLWAYTALLSIQDLLLEELNSSETLTKSACMQILESHSPELQELERKLEDQLAHQEAAQLQRALDSWQQWAGEGPALLQEPEETDSERHVSAVLQRALSKGQKLLEYHQQSLREEQEDSVVLEDLLENMETDTFVTLYGQELRLASYLSKLTMLPGGTLRRLLTVALPAASQAELLAVLDSVGQKHQDHSVENDGSRVQADLGRRGKHQGWWQALESKLRGELINRGLEKMLWAQKRKESILKKTCPPLRERVIFSGKRSWPHLSLESTDELTPVPIVGAEAVDLLNTGEKLFIFRNPKEPEISLHVPPRKKKKNFLNAKKAAWALGLN", "length": 1300, "header": "tr|E1BES3-1|E1BES3_BOVIN Isoform 1 of EvC ciliary complex subunit 2 OS=Bos taurus OX=9913 GN=EVC2 PE=4 SV=3 CANONICAL=E1BES3-1" }, "locus": { "chromosome": "6", "start_pos": 103662342, "end_pos": 103500717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005613.8", "url": "https://www.ensembl.org/id/ENSBTAT00000005613.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005613.6", "url": "https://www.ensembl.org/id/ENSBTAP00000005613.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5632684", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5632684", "resource": "Reactome", "description": "Hedgehog 'on' state" }, { "id": "R-BTA-5635838", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5635838", "resource": "Reactome", "description": "Activation of SMO" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M8S3-1", "protein_name": "Limbin isoform X2", "gene_name": "Evc2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGATGPTGARGRATWVLAGGVLAAALVLGAGPRAFSPAFPALGPGSPNRPGPGGPQPSLQYRDISREAQGPSENGIIFQKCSLVSGKSKSQAMHVQLSVNNTRTPLSTNLSDLLVLDEITSLIVKESPGNKTRDGIQTFRKRFLQVGEFYSVSYMASLDPTALGTGEILDLPALLIFQSPSQNRTQLKAHFTITVEEKITVLPNHGLHAAGFIAAFLISLVLTLVALFFLAKGRCLQGNVLTRCRVQHAENKLEPSPFTSANGVSQDLSFNDQVIDILTSEDPGSMLQALEELEIATLNQADADLEACRNQISKDIIALLMKNLASGGHLSPQTQRKVTAALKEQFLLLEKEIQEEYERKMLALTAECDLEARKKTESQYQREMVAMEEAEEVLKRVSERSAAECSSLLRTLHGLEQEDMQRSLALHQAEDFAQAHRQLVVFQRNELHNIVYTQIQSAVAKGELRPEVAKMLLQDYSKTQESVEELMDFFQATKRYHLSKRFGHREYLVQSLQAMETRVQGLLSTAAAQLTSLIHKHERAGYLDEDQMEMLLERAQTETFSIKQKLDNDLKQEKKRLHQKLITKRRRELLQKHKEQQKEQVSLGEASSTAEDAVQYLYQWRSVMAEHTAALEELQERLDQAALDDLRVLTVSLSEKATEELRRLQSTAMTQELLKRSAPWLFLQQILEEHSRESAARTAQLEAEERQHGQELVQGVRQRLQQDLPEACTEEQAELRHWEHLVFIALLRNQPCCQENQARKLCCAAISLSEEDLLRVRQEAQGCFTQLDRSLALPRVRARVLQQQLQMAWREAEFRKLDQALAAPELQSKTRKLRSKGRGKADLLKKILEDKIRLFEERTPEDLADKVRGELLHERVQRLEAQEAHFAESLVALQFQKVARAAETLSVYTALLTIQDLLLGELSESETLTKSACAQILESHSPELQELERKLEERLVQQEAAEQQQVLESWQQWMADGPGLGEPGEMDPERQVSAMLRQALNKGQKLLEQQQQRVREERQNSAVLEDSLESMEADTMASLCSQGLRLVSYLSKMTMVPGSTLLRLLGVVLPAASQPQLLALLDTVSEKHSDHTAENGSSGDQAEQGKRRKHQGWWQALDSRLRADLVSQGLERMLWARRKKESILKKVYTPVQERVTFPGKGSWPHLSLEPIGELAPMPITGVDTMDILNTGEKIFVFKSPKEPEISLRVPPRRKKNFLNAKKASRALGLD", "length": 1230 }, "evidence": [ { "id": "E1BES3", "url": "https://omabrowser.org/oma/group/E1BES3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0YCE0-1", "protein_name": "EvC ciliary complex subunit 2", "gene_name": "EVC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDAKAEARSGSGQRGAPRAGPVPCGAGRLLAGLLVVLLSSAPAQPLGAAAWCPTQGHGVPGPPRGHCGRTAAGVITDDPWLQKEMNCLRMTALQLPVVVQASEVPDLILTSAASEDQWSHSIFALISSWTRKILFKRESSVNHQLSFPLPPQPEDVSNLSASSGFGITLQKCAVVDVEHDPQTAYIRLLINNTNSLLSRNITDLILLDNITGLHVQKDSGNETRDGMQIYRKRFLQVGEYFAINYTALLDAKKTWKGRVLTLPAQLTFRSSSQNQTDLVSLTTLFTITEEEKTEVSYSHAIHASGFFIAFFVSLVLTCAVFFILYRTQLLRWSFYSENQEIQHELSQNHKLEHSQFSSGDLFSEGVIMNDQIIDILTFEESGNMLQALEDLEVASLTRADADLEAYRMQICKEVIAIMMKNMVLSHSLIPHVEKRMSSIFKKQFLTMEREFQEEYERKVVALTAECNLETRKKMEAQRQKERAANEEAEELIRKVNEMPAVEYKSLLDRLHSLEQDHLKRFLLVKQEEYFAKAYRQLAVSQRKELHNIFFTQITNATFKGELKLEIAKSLVEDYSKIQGDIEELMDFLQASKKYHLNRRFAYREYLIKKIQLRDSQASALINAAATQILNLINKMERAGHLHESHLGMLLDRAEAEINSVKQKFNHDLKQEKQKLQQKLITKRKWKMLQKKEHWKEQLSIGNPFKTSREITDYLSHWKTVLSDHAIEFEELTEKLDNEGSEELRDLIFNLAEKTVEELKLVQYGVFVQELIKLSVPKMFLLEVVEEHKKEFIVKHEHLEREEREKSMAAEELLQLTRQKLSQELESSLSQQKKLRNWEQSVFMQLLTLPLSLSEEELLKMRQEFHCCFSQLDSSLALPKIRARALLQAFELEWRDAQLLKVSQNLAMTNKQPHSKTKKTGSKNRNKIDVLKKSLQDKIFIYEDSVKVENLTKVNYELLLEKDCQIHDLENKLGEYIASLEFQKSVKKCKMLELYAAVISVQGLLLENLSMSKTLSKSECIQILEAHNPEIEELDRKLEYEMLHKESAQQQQHLMNKQRWTPDGLRPSSEVVETNVDRQVTFLLRQAMNRCMQFINLHRQSLRDEQWNCMVLEDLLENIEMDAFLALYSQELRLAGYLARLTRVPMGMLHRILNLLLPSSSQSEVLSILDSIGVYSDGAAESDSNADESGSCKKRRNQECWQALEYKVREDLISKSLERILSLNRRKDSLIKKKQLALLERPSFIHLESLPTRPPVERSTPHVSFNSVTAEAIEVLDTGEKIFLFRDRSDPTLSFHNYPRKKKKNFLNSKKAARANIN", "length": 1317 }, "evidence": [ { "id": "E1BES3", "url": "https://omabrowser.org/oma/group/E1BES3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZWN3-1", "protein_name": "EvC ciliary complex subunit 2", "gene_name": "Evc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATGLTGTGGQATWVLAGNILAAALVLGVGPCALPPSFPALGPGSPSPPDPVGPRASSQHSDISRDAQGPSENGVIFQKCSLVSGQSESQTMHVQLSVNNTRTPMSANLSDLLVLDDITGLTVKESPGNVTQEGIQTFRKRFLQVGECYSVSYMASLDPTALGPGESLDLPAQLIFQRPSQNRTQLRARFTITVEEKIMVQHPENKLEPSPFTSANGVSQDLSLNDQLVAILTSEEPGSMLQALEELEIATLNQADADLEACRNQISKDIIALLMKNLISGGHLSLQTERKMAAAFKKQFLLLENEIQEEYERKMLALTAECDLEVRKKTENQYQREMVAMEEAEEVLKRVSERSAAECSSLLRTLHGLEQEDLQRSLTLQQAEDFAQAHRQLAVFQRNELHSIVYTQIQSAVAKGELRPEVAKMLLQDYSKTQESIEELMDFFQATKRYHLSKRFGHREYLVQRLQAMETRVQGLLSTAATQLTSLIHKHERAGYLDEDQMEMLLERAQTETFSIKQKLDNDLKQEKKRLHQKLITKRRRELLQKHKEQQKEQVSLGEASSTAEDAIQYLQQWRSVMAEHTTALEELQERLDQAALDDLRVLTVSLSEKATEELRRLQSTAMTQELLKRSAPWLFLQQILEEHSRESAARTAQLEAEERERGQELVQGVRQRLQQDAPEACTEEQAELRHWEHLVFTKLCSAAISLSEEDLLRVRQEAQGCFTQLDRSLALPRVRARVLQQQMQMTWREAEFRKLDQALAVPELQSKSRKLRSKGRGKADLLKKNLEDKIRLFEERAPEDLADQVRGELLQERVQRLEAQEAHFAESLVALQFQKVARAAETLSVYTALLSIQDLLLGELSESETLTKSACVQILESHRPELLELERMLEDRLVQQEEAEQRRVLESRQRWAADGPALGEPEEIDPERQVSAVLRQALNKGQKLLEQYQQRVREEQQNGAVLEDSLESMETDTMASLCSQGLRLVSYLSRMTMVPGGTLLRLLSVVLPAASQPQLLALLDAVSEKHSDHTAENESGGEQAQAEQGKRRKHQSWWKALDSRFRADLVSQGLERMLWARRKKESILKKRYVPVQERVVFPGKGSWPHLSLEPIGELAPIPITGLDTMDILNTGEKIFVFRSPKEPEISLRVPPRRKKNFLNAKAASRALGLD", "length": 1172 }, "evidence": [ { "id": "E1BES3", "url": "https://omabrowser.org/oma/group/E1BES3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86UK5-1", "protein_name": "Limbin", "gene_name": "EVC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPSGSRGRPTWVLAGGLLAVALALGGRGCLGASSRPRWRPLGAQPPRDPQVAPRSGPGLRIPPGRSGAGPESSTQDLPCMIWPKVECCHFKTAVEAPLGMKLDKKMEVFIPLSTSAASSGPWAHSLFAFIPSWPKKNLFKRESPITHRLYGDISREVQGTSENGVIFQKCALVSGSSEAQTARIWLLVNNTKTTSSANLSELLLLDSIAGLTIWDSVGNRTSEGFQAFSKKFLQVGDAFAVSYAATLQAGDLGNGESLKLPAQLTFQSSSRNRTQLKVLFSITAEENVTVLPHHGLHAAGFFIAFLLSLVLTWAALFLMVRYQCLKGNMLTRHRVWQYESKLEPLPFTSADGVNEDLSLNDQMIDILSSEDPGSMLQALEELEIATLNRADADLEACRTQISKDIIALLLKNLTSSGHLSPQVERKMSAVFKKQFLLLENEIQEEYDRKMVALTAECDLETRKKMENQYQREMMAMEEAEELLKRAGERSAVECSNLLRTLHGLEQEHLRKSLALQQEEDFAKAHRQLAVFQRNELHSIFFTQIKSAIFKGELKPEAAKMLLQNYSKIQENVEELMDFFQASKRYHLSKRFGHREYLVQNLQSSETRVQGLLSTAAAQLTHLIQKHERAGYLDEDQMEMLLERAQTEVFSIKQKLDNDLKQEKKKLHQKLITKRRRELLQKHREQRREQASVGEAFRTVEDAGQYLHQKRSLMEEHGATLEELQERLDQAALDDLRTLTLSLFEKATDELRRLQNSAMTQELLKRGVPWLFLQQILEEHGKEMAARAEQLEGEERDRDQEGVQSVRQRLKDDAPEAVTEEQAELRRWEHLIFMKLCSSVFSLSEEELLRMRQEVHGCFAQMDRSLALPKIRARVLLQQFQTAWREAEFVKLDQAVAAPELQQQSKVRKSRSKSKSKGELLKKCIEDKIHLCEEQASEDLVEKVRGELLRERVQRMEAQEGGFAQSLVALQFQKASRVTETLSAYTALLSIQDLLLEELSASEMLTKSACTQILESHSRELQELERKLEDQLVQQEAAQQQQALASWQQWVADGPGILNEPGEVDSERQVSTVLHQALSKSQTLLEQHQQCLREEQQNSVVLEDLLENMEADTFATLCSQELRLASYLARMAMVPGATLRRLLSVVLPTASQPQLLALLDSATERHVDHAAESDGGAEQADVGRRRKHQSWWQALDGKLRGDLISRGLEKMLWARKRKQSILKKTCLPLRERMIFSGKGSWPHLSLEPIGELAPVPIVGAETIDLLNTGEKLFIFRNPKEPEISLHVPPRKKKNFLNAKKAMRALGMD", "length": 1308 }, "evidence": [ { "id": "E1BES3", "url": "https://omabrowser.org/oma/group/E1BES3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K1G2-1", "protein_name": "Limbin", "gene_name": "Evc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGATGPTGAGGRATWVLAGNILAAALVLGSGPRALPPSFPALGPGSPSRPGPAGPWASSQYSDISREARGPFENGVIFQKCSLVSGQSESQTMHVQLSVNNTRTPTSVNLSNLLVLDEITGLAVKESPGNNTQDGIQTFRKSFLQVGECYSVSYTASLDPTALGTGESLDLPARLIFQSPSQNRTQLKAPFTITVEEKIMVLPNHGLHAAGFIAAFLISLLLTVAALFFLARGRCLQGGMLSRCRIQHPENKLEPSPFTSANGVSQDLSLNDQVVAILTSEEPGSMLQALEELEIATLNQADADLEACRNQISKDIIALLMKNLVSGGHLSPQTERKMAAAFKKQFLLLENEIQEEYERKMLALTAECDLEMRKKTENQYQREMVAMEEAEEVLKRVSERSAAECSSLLRTLHGLEQEDMQRSLTLDQAEDFAQAHRQLAVFQRNELHSIVYTQIQSAVSKGELRPEVAKMMLQDYSKTQESVEELMDFFQATKRYHLSKRFGHREYLVQRLQAMETRVQGLLNTAATQLTSLIHKHERAGYLDEDQMETLLERAQTETFSIKQKLDNDLKQEKKRLHQRLITRRRRELLQKHKEQQKEQVSLGEASSTAEDAVQYLHQWRSVMAEHTAALEELQERLDQAALDDLRVLTVSLSEKATEELRRLQSTAMTQELLKRSAPWLFLQQILEEHSRESAARTTQLEAEERERGQELVQGVRQRLQQDALEAYTEEQAELRHWEHLVFMKLCCAAISLSEEDLLRVRQEAQGCFSQLDRSLALPRVRARVLQQQAQMAWREAEFRKLDQALAAPELQSKARKLRSKGRGKADLLKKNLEDKIRLFEERAPVELADQVRGELLQERVQRLEAQEAHFAESLVALQFQKVARAAETLSVYTALLSIQDLLLGELSESETLTKSACVQILESHRPELQELQELERKLEDQLVQQEEAEQQRVLESWQRWAADGPGLSEPEEMDPERQVSAILRQALNKGQKLLEQHQQRVREEWQNGAVLEDSLESIEADTMASLCSQGLRLVSYLSRMTMVPGSTLLRLLSVVLPAASQPQLLALLDAVSEKHSDHTAENESSGEQAQAEQSKRRKHQVWWKVLDSRFRADLVSQGLERMLWARQKKERILKKIYVPVQERVMFPGKGSWPHLSLEPIGELAPIPITGADAMDILNTGEKIFVFRSPREPEISLRVPPRRKKNFLNAKKANRALGLD", "length": 1220 }, "evidence": [ { "id": "E1BES3", "url": "https://omabrowser.org/oma/group/E1BES3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "E1BES3", "url": "https://www.uniprot.org/uniprotkb/E1BES3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "E1BES3", "url": "https://www.uniprot.org/uniprotkb/E1BES3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BES3", "url": "https://www.uniprot.org/uniprotkb/E1BES3" } ], "pmid": "" }, { "name": "plasma membrane protein complex", "id": "GO:0098797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098797", "evidence": [ { "database": "UniProtKB", "id": "E1BES3", "url": "https://www.uniprot.org/uniprotkb/E1BES3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 991, "end_pos": 993, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BES3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BES3" }, { "id": "PF12297", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12297" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Limbin", "eco_id": "ECO_0000259", "start_pos": 235, "end_pos": 740, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 404, "end_pos": 406 }, { "start_pos": 991, "end_pos": 993 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHU1-1", "uniprot_ac": "E1BHU1", "uniprot_id": "E1BHU1_BOVIN", "mass": { "chemical_mass": 149529.0, "monoisotopic_mass": 149529.0 }, "refseq": { "ac": "XP_002689339", "name": "treacle protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689339" }, "gene_names": [ { "name": "TCOF1", "type": "recommended", "evidence": [ { "id": "E1BHU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" } ] }, { "name": "TCOF1", "type": "synonym", "evidence": [ { "id": "XP_002689339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689339" } ] } ], "protein_names": [ { "name": "Treacle ribosome biosis factor 1", "type": "synonym", "evidence": [ { "id": "E1BHU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHU1/entry#names_and_taxonomy" } ] }, { "name": "treacle protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002689339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689339" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHU1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TCOF1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1", "locus": { "chromosome": "7", "start_pos": 61746778, "end_pos": 61708311, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015224", "url": "https://www.ensembl.org/id/ENSBTAG00000015224" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015224", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015224", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "513591", "url": "https://www.ncbi.nlm.nih.gov/gene/513591", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513591", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513591", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VYDTPRN", "url": "https://omabrowser.org/oma/group/VYDTPRN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LFY9", "url": "https://www.orthodb.org/?gene=A0A3Q1LFY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LX56", "url": "https://www.orthodb.org/?gene=A0A3Q1LX56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BHU1", "url": "https://www.orthodb.org/?gene=E1BHU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20787", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20787", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20787:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20787:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002689339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFY9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LX56", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LX56-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHU1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHU1-1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEARKRRELLPLIYQHLLQAGYVRAAREVKEQSGQKIFLSQPVTLLDIYTHWQQTSEIGRKRKAEEDAALQAKRSRVSDPISSSESSEEEEEEEEAEAKTTKPTPRLAATNSSVTGTVSSSNVKEKAKAKTTKASKTVNSTTHPAPGKAVAHLLTGKSPQKTSGPSANAVLVSETEEEGSVSALRTATTPGMASADQADSSSEDTTSSSDETDLEAKAAVKPLQVRASATAVKESPRKSAAPTPGKAGVVTPQVRGGAVTPASRAKKPEEVSESSEESDESEEAAPAGTPSQVKALEKTVPIRVAPSPAKGTPGKGATPAPPGKAGPLGKPEEDSESSSEESDSEEETQAVKTPVQAKPSGKIPQVKAASTPKIQVFFPKKGSPPTSPGKAGPAATQAQPRKQEEEESSSSSSKESDSEGEVPTAMQQTTSLAQAKPLEKNSQVRAASATGAGPSAKGTVPALPQKARSVAAQDGKQEDSESSSEEESDSEEEMQKAGTSAQAQSSGKALQIRPASGPTKRPPQKAGPATTQVKVERAEEDSESSEEESDSEDEAPVAKTPAQAKSAVKTSQIKASPRKGTPITPSSARVPPVQVGTPAPRTAAAVSTPTCASSPAIVRHTQKPGEDSSSSEESESEEETAPAAAGGQMKSIGKTLPVKAASPATKGPSGKGTTPGPPGKAGPAVAQVKAEVQEDSESSEESDNEEAAATPAQVKTSVKTPQTKANSSATRVASAKAAAPAPGKGGLAVAQAKVGSPAKVKPPARTPQSSAVSGRGQVSVPAVGKAAAAAAQAQPGPVKGSQEDSESSEEESDSEGEAPPQGKPSGKTPQVRTASAPTKASPKKGAAPVPPGKAGPPATQAKRQEEDSESSSEEESDSDGDVPAAAPPAQKEGSSKTATSKTLAPASLEKKAEESSTSSDEDLPSSQVIKTPLIFVDPNRSPAGPAATPAQAQATGTLRKAQALESTARSSSESEDEDVIPATQCPTPATRTSVVTVPTAPPKAALRASVVGAPSSEDTSQGSEGKKQEASATQVTKRNLPLTQAALKVLAQKASEAQSPAAKTPSSSGTDSAVGTLSTASPQSTPTQVRMANKLRKPEVPTAQQATATPSGHPTAKAPATSDDSNSSSSGSEDDAKGSQAAPSAHRPGPAPSRRETLVEETTTESSDDEVVAPSQSLLSGFVTPGLTPAGSKTSKAAPKPDASPSVSSTPATRDAPEGKQEVEPQQAAGTMSPKTGRKEAGATPQKPGKGLGSPPASMLALQSNITQRLLSEPWPLSEAQVQASVAKVLTELLEQERKKAMDTAKEGSRKGRLGHKRKLSEDQTAPKAPKNKKKKQLAAADGGEHVVSSEKAPRTVKGKSKKDRASGDVKEKKEKESPGSQGAKEKPVGELGTPKGDGGDHGNLKMKKEKKKSDKKKKDKEKKEKKKKAKKASTKDPGSPSQKKKKRKKKTAEQTV", "length": 1458, "header": "tr|E1BHU1-1|E1BHU1_BOVIN Isoform 1 of Treacle ribosome biosis factor 1 OS=Bos taurus OX=9913 GN=TCOF1 PE=1 SV=2 CANONICAL=E1BHU1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFY9-1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1/entry#A0A3Q1LFY9-1", "sequence": { "sequence": "MAEARKRRELLPLIYQHLLQAGYVRAAREVKEQSGQKIFLSQPVTLLDIYTHWQQTSEIGRKRKAEEDAALQAKRSRVSDPISSSESSEEEEEEEEAEAKTTKPTPRLAATNSSVTGTVSSSNVKEKAKAKTTKASKTVNSTTHPAPGKAVAHLLTGKSPQKTSGPSANAVLVSETEEEGSVSALRTATTPGMASADQADSSSEDTTSSSDETDLEAKAAVKPLQVRASATAVKESPRKSAAPTPGKAGVVTPQVRGGAVTPASRAKKPEEVSESSEESDESEEAAPAGTPSQVKALEKTVPIRVAPSPAKGTPGKGATPAPPGKAGPLGKPEEDSESSSEESDSEEETQAVKTPVQAKPSGKIPQVKAASTPKIQVFFPKKGSPPTSPGKAGPAATQAQPRKQEEEESSSSSSKESDSEGEVPTAMQQTTSLAQAKPLEKNSQVRAASATGAGPSAKGTVPALPQKARSVAAQDGKQEDSESSSEEESDSEEEMQKAGTSAQAQSSGKALQIRPASGPTKRPPQKAGPATTQVKVERAEEDSESSEEESDSEDEAPVAKTPAQAKSAVKTSQIKASPRKGTPITPSSARVPPVQVGTPAPRTAAAVSTPTCASSPAIVRHTQKPGEDSSSSEESESEEETAPAAAGGQMKSIGKTLPVKAASPATKGPSGKGTTPGPPGKAGPAVAQVKAEVQEDSESSEESDNEEAAATPAQVKTSVKTPQTKANSSATRVASAKAAAPAPGKGGLAVAQAKVGSPAKVKPPARTPQSSAVSGRGQVSVPAVGKAAAAAAQAQPGPVKGSQEDSESSEEESDSEGEAPPQGKPSGKTPQVRTASAPTKASPKKGAAPVPPGKAGPPATQAKRQEEDSESSSEEESDSDGDVPAAAPPAQKEGSSKTATSKTLAPASLEKKAEESSTSSDEDLPSSQVTKRNLPLTQAALKVLAQKASEAQSPAAKTPSSSGTDSAVGTLSTASPQSTPTQVRMANKLRKPEVPTAQQATATPSGHPTAKAPATSDDSNSSSSGSEDDAKGSQAAPSAHRPGPAPSRRETLVEETTTESSDDEVVAPSQSLLSGFVTPGLTPAGSKTSKAAPKPDASPSVSSTPATRDAPEGKQEVEPQQAAGTMSPKTGRKEAGATPQKPGKGLGSPPASMLALQSNITQRLLSEPWPLSEAQVQASVAKVLTELLEQERKKAMDTAKEGSRKGRLGHKRKLSEDQTAPKAPKNKKKKQLAAADGGEHVVSSEKAPRTVKGKSKKDRASGDVKEKKEKESPGSQGAKEKPVGELGTPKGDGGDHGNLKMKKEKKKSDKKKKDKEKKEKKKKAKKASTKDPGSPSQKKKKRKKKTAEQTV", "length": 1351, "header": "tr|A0A3Q1LFY9-1|E1BHU1_BOVIN Computationally mapped isoform of Treacle ribosome biosis factor 1 OS=Bos taurus OX=9913 GN=TCOF1 PE=1 SV=1 CANONICAL=E1BHU1-1" }, "locus": { "chromosome": "7", "start_pos": 61745574, "end_pos": 61708318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072043.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072043.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057207.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057207.1" } ] } }, { "isoform_ac": "A0A3Q1LX56-1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1/entry#A0A3Q1LX56-1", "sequence": { "sequence": "MAEARKRRELLPLIYQHLLQAGYVRAAREVKEQSGQKIFLSQPVTLLDIYTHWQQTSEIGRKRKAEEDAALQAKRSRVSDPISSSESSEEEEEEEEAEAKTTKPTPRLAATNSSVTGTVSSSNVKEKAKAKTTKASKTVNSTTHPAPGKAVAHLLTGKSPQKTSGPSANAVLVSETEEEGSVSALRTATTPGMASADQADSSSEDTTSSSDETDLEAKAAVKPLQVRASATAVKESPRKSAAPTPGKAGVVTPQVRGGAVTPASRAKKPEEVSESSEESDESEEAAPAGTPSQAKPSGKIPQVKAASTPKIQVFFPKKGSPPTSPGKAGPAATQAQPRKQEEEESSSSSSKESDSEGEVPTAMQQTTSLAQAKPLEKNSQVRAASATGAGPSAKGTVPALPQKARSVAAQDGKQEDSESSSEEESDSEEEMQKAGTSAQAQSSGKALQIRPASGPTKRPPQKAGPATTQVKVERAEEDSESSEEESDSEDEAPVAKTPAQAKSAVKTSQIKASPRKGTPITPSSARVPPVQVGTPAPRTAAAVSTPTCASSPAIVRHTQKPGEDSSSSEESESEEETAPAAAGGQMKSIGKTLPVKAASPATKGPSGKGTTPGPPGKAGPAVAQVKAEVQEDSESSEESDNEEAAATPAQVKTSVKTPQTKANSSATRVASAKAAAPAPGKGGLAVAQAKVGSPAKVKPPARTPQSSAVSGRGQVSVPAVGKAAAAAAQAQPGPVKGSQEDSESSEEESDSEGEAPPQGKPSGKTPQVRTASAPTKASPKKGAAPVPPGKAGPPATQAKRQEEDSESSSEEESDSDGDVPAAAPPAQKEGSSKTATSKTLAPASLEKKAEESSTSSDEDLPSSQVIKTPLIFVDPNRSPAGPAATPAQAQATGTLRKAQALESTARSSSESEDEDVIPATQCPTPATRTSVVTVPTAPPKAALRASVVGAPSSEDTSQGSEGKKQEASATQVTKRNLPLTQAALKVLAQKASEAQSPAAKTPSSSGTDSAVGTLSTASPQSTPTQVRMANKLRKPEVPTAQQATATPSGHPTAKAPATSDDSNSSSSGSEDDAKGSQAAPSAHRPGPAPSRRETLVEETTTESSDDEVVAPSQSLLSGFVTPGLTPAGSKTSKAAPKPDASPSVSSTPATRDAPEGKQEVEPQQAAGTMSPKTGRKEAGATPQKPGKGLGSPPASMLALQSNITQRLLSEPWPLSEAQVQASVAKVLTELLEQERKKAMDTAKEGSRKGRLGHKRKLSEDQTAPKAPKNKKKKQLAAADGGEHVVSSEKAPRTVKGKSKKDRASGDVKEKKEKESPGSQGAKEKPVGELGTPKGDGGDHGNLKMKKEKKKSDKKKKDKEKKEKKKKAKKASTKDPGSPSQKKKKRKKKTAEQTV", "length": 1394, "header": "tr|A0A3Q1LX56-1|E1BHU1_BOVIN Computationally mapped isoform of Treacle ribosome biosis factor 1 OS=Bos taurus OX=9913 GN=TCOF1 PE=1 SV=1 CANONICAL=E1BHU1-1" }, "locus": { "chromosome": "7", "start_pos": 61745574, "end_pos": 61708318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070090.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070090.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062051.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062051.1" } ] } }, { "isoform_ac": "E1BHU1-1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1/entry#E1BHU1-1", "sequence": { "sequence": "MAEARKRRELLPLIYQHLLQAGYVRAAREVKEQSGQKIFLSQPVTLLDIYTHWQQTSEIGRKRKAEEDAALQAKRSRVSDPISSSESSEEEEEEEEAEAKTTKPTPRLAATNSSVTGTVSSSNVKEKAKAKTTKASKTVNSTTHPAPGKAVAHLLTGKSPQKTSGPSANAVLVSETEEEGSVSALRTATTPGMASADQADSSSEDTTSSSDETDLEAKAAVKPLQVRASATAVKESPRKSAAPTPGKAGVVTPQVRGGAVTPASRAKKPEEVSESSEESDESEEAAPAGTPSQVKALEKTVPIRVAPSPAKGTPGKGATPAPPGKAGPLGKPEEDSESSSEESDSEEETQAVKTPVQAKPSGKIPQVKAASTPKIQVFFPKKGSPPTSPGKAGPAATQAQPRKQEEEESSSSSSKESDSEGEVPTAMQQTTSLAQAKPLEKNSQVRAASATGAGPSAKGTVPALPQKARSVAAQDGKQEDSESSSEEESDSEEEMQKAGTSAQAQSSGKALQIRPASGPTKRPPQKAGPATTQVKVERAEEDSESSEEESDSEDEAPVAKTPAQAKSAVKTSQIKASPRKGTPITPSSARVPPVQVGTPAPRTAAAVSTPTCASSPAIVRHTQKPGEDSSSSEESESEEETAPAAAGGQMKSIGKTLPVKAASPATKGPSGKGTTPGPPGKAGPAVAQVKAEVQEDSESSEESDNEEAAATPAQVKTSVKTPQTKANSSATRVASAKAAAPAPGKGGLAVAQAKVGSPAKVKPPARTPQSSAVSGRGQVSVPAVGKAAAAAAQAQPGPVKGSQEDSESSEEESDSEGEAPPQGKPSGKTPQVRTASAPTKASPKKGAAPVPPGKAGPPATQAKRQEEDSESSSEEESDSDGDVPAAAPPAQKEGSSKTATSKTLAPASLEKKAEESSTSSDEDLPSSQVIKTPLIFVDPNRSPAGPAATPAQAQATGTLRKAQALESTARSSSESEDEDVIPATQCPTPATRTSVVTVPTAPPKAALRASVVGAPSSEDTSQGSEGKKQEASATQVTKRNLPLTQAALKVLAQKASEAQSPAAKTPSSSGTDSAVGTLSTASPQSTPTQVRMANKLRKPEVPTAQQATATPSGHPTAKAPATSDDSNSSSSGSEDDAKGSQAAPSAHRPGPAPSRRETLVEETTTESSDDEVVAPSQSLLSGFVTPGLTPAGSKTSKAAPKPDASPSVSSTPATRDAPEGKQEVEPQQAAGTMSPKTGRKEAGATPQKPGKGLGSPPASMLALQSNITQRLLSEPWPLSEAQVQASVAKVLTELLEQERKKAMDTAKEGSRKGRLGHKRKLSEDQTAPKAPKNKKKKQLAAADGGEHVVSSEKAPRTVKGKSKKDRASGDVKEKKEKESPGSQGAKEKPVGELGTPKGDGGDHGNLKMKKEKKKSDKKKKDKEKKEKKKKAKKASTKDPGSPSQKKKKRKKKTAEQTV", "length": 1458, "header": "tr|E1BHU1-1|E1BHU1_BOVIN Isoform 1 of Treacle ribosome biosis factor 1 OS=Bos taurus OX=9913 GN=TCOF1 PE=1 SV=2 CANONICAL=E1BHU1-1" }, "locus": { "chromosome": "7", "start_pos": 61745574, "end_pos": 61708318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020259.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020259.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020259.5", "url": "https://www.ensembl.org/id/ENSBTAP00000020259.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1110, "start_aa": "Thr", "end_pos": 1110, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1110", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1185, "start_aa": "Thr", "end_pos": 1185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1185", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1211, "start_aa": "Thr", "end_pos": 1211, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1211", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 244, "start_aa": "Thr", "end_pos": 244, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr244", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 261, "start_aa": "Thr", "end_pos": 261, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr261", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 290, "start_aa": "Thr", "end_pos": 290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr290", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 675, "start_aa": "Thr", "end_pos": 675, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr675", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 711, "start_aa": "Thr", "end_pos": 711, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr711", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 949, "start_aa": "Thr", "end_pos": 949, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr949", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 988, "start_aa": "Thr", "end_pos": 988, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr988", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:513591", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513591", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R8J0-1", "protein_name": "Treacle ribosome biosis factor 1", "gene_name": "TCOF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNQRTPKVLHLNTALRAGNEAQVLRQDRRRPCGDTQGSFPAEVDAAVRSERREKSFLTQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISSSESSEEEEEEEEAAEARNAKATPRPASTNSSVPGPVLPSSIKDEGAAKTKKASQTGNPTARAASGKPVAQLLGQKSPRKAAGPSANAVLASETEEEGSVSALRTAAKPGMTAASQAHSSSEDTSSSSDETDVEGKPLVAPAQVKASAATAQEPPRKRAPPTPGKAGAGTPQGRGGTLTPASRAKKPEEVSESSEEESESDDQAPASTPSQTKASEKTQVRAASGPARGAPGKGATPAPPGRAGPAAARDKVVKPEEGSESSSEEASSSSDSEEEAPAAKTPPQAKPPGKVPGVRATSAAPAKESPRKGAPPAPASRAAQAGQREEDSESSSEESDAGGQAAAAAPQTSSPALVKPMGQNSHGRAPRALAGKGAVPALPGQAGQQDSGSSSEDSDSGDSEEEAATTAKPSEKVLPARTASGPSTGPPQKARPAATQVKAERSESSEESSTDSEEEAPAAAAAAQAKPAVKTPQTKASPRKGGPVTPASAKAAPVRVGTPAPWKAGATTASPATAKAAQRPEADSSSSETSESEEEEEEAPPAAAAGRMKNSVTAPQTKATPAVPRVASAKVAASAPGKGAPAGAQATLGSPAKVRPPARTPQGRPGAGKGPGAVPAVGKAATTAAPQPGPVGGAEDDSESSDGDSDSEEAAPAQAKPTRKTPQVRAASAPSKASPRKGAAPAPAGKTGPPATQAGKPTEDSESSSEESSGSDGEAPPAQGGGCSPASGRPPAATASAGKAEQKKTKEEKAEGPSASSDDELPASQVIKTPLIFVDPNRSPAGPAATLAQAQATSAGRKVQASESTAGSSSESEDEDVVPATQCSAPALRTSSATAPPVPPRTAPRASSGKEPGQAAEGRKPEAPATQVTKRSPADLPLTQAALKVLAQKASEGRPAAARTPSSCATDGLGTLPTTRPQSAPAQTRGANELRKPGVPAAPPSKRPKAKASGTSEDSEDGSSSSSSGSEDDAAGPRVAPGAPGPGAAPARKETLVEETTAESSDDEVVAPSQSLLSGYVTPGLTPGTSQASKTTPKPAPSPSVSSPPATKDALGGKRGAEAPRAAGTTSPKSGRGEAGATPQRPREGPESPQASRLALQHDIARRLLGEPWPLSEAHVQASVAKVLTELLEQERRKAADAAREGRRKGRKRKLSEDQTAAKAPKSKKKKQLAAGEGGERAVSPDKAPRTCQGKPKRDRAGGASKEKQEKEAPGSQGAKEKLEGEPGMVKGEGGDQGAPRSKKEKKKPDKSKCSRRPAGSCPHAGGQPLASTGPRLACPGSRGRIGRARARFGTTGPPLPRG", "length": 1399 }, "evidence": [ { "id": "E1BHU1", "url": "https://omabrowser.org/oma/group/E1BHU1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A206-1", "protein_name": "Treacle ribosome biogenesis factor 1", "gene_name": "Tcof1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEARKRRELLPLIYHHLLQAGYVRAAREVKEQSGQKNFLTHPVTLLDIYTHWQQTSELGLKQKAENDETLQAKKSRVSDPISSSESSEEEEEEAETGTAKATPRPTPVNSTAAALPSNMKQKAKTKTANKTVNSVLPPASGKTAVQLLSGKSPKKSAEPLASIVLASETEEEGSAQVLGPTAKPGMVSAGQASSSSEDTSSSSDETDVEVKPSTKPQAKAPVTPAKDPPARTASGPTKLGDVTPASARAAATKAAESESSEEDSESEDEAPAGLPSQVTTPGKGLHVRAASVSAKGMSRKGPISATPEKTGPITPQAKTGRPQKDMETSSEDDSDSEDEMPVTVTTPQARPSGKSPQVRGTSAPAKESSQKGAPAVTPGKTRPVAAQAQAGKPETRSSEESESDSGETPAAGTLTTSPAKVKPLGKSPQVRPASTANLGSSRKGANPPCLGKVGSAVLKVQTGKEEEDSESSSEESDSDGAVNAAKAKPPGRKATPALPRKTGPVATQVKTDKGKDHAESSEESTDSEEEAAPAASAAQAKPAPIKQMKASPRKGTAASTTGASASSPRKAGTKTSSASLSSLALPKGTQKPDVDSSSEWESEGAAPGTTGVQGKSGGKGLQGRAASGQGVAPLHAQKTGPSGAQVKATAQEDSESSEEESSSEEEDETPAQVMALGRLPPAKANPPPTKTPLASASGKAAAVVPPPKGKAPASTVQNSTISARGQRAVPATGKAGAPATQAQKGPMAGTGEDSESSSEEESDSEEETPAQVKPVGKTSQVRAASAPVKESPNKGAYSGTSRKTGPPATQAQTGKTEDSESSSEESDSDREIPPAITPAQDGISQSTRSKLSGLAPPEKSTEESSESSDEDLPSGQAIKSPPISVNPNRGPAAPVPTPEQHQAVNTRKAQASGSTAQSSSSESEDEDMIPATQPPTLAIRTNVTTPTALSQTAAQPSKSEQSSRMPKGKKPKTASTQISSAMEALPVTLPQSTPAQSKTTNKLGDPKLAEKQQLTPGYPKAPRSSEDSSDTSSESEEDAKRPQMSKSSQRLDPDASQKETVVEETPTESSDDEMVAPSQSLLSGYVTPGLTVANSQPSKATPRPDANPLVSSAPATKDNPDGKQKSKSQDSTADTTLRKTGRKEASSGSTPQKPKKPKKSTLSSPAPAQTLPNSITQRLLEQPWPLSEAQVQASVMKVLTELLEQERQKATEAIKESGKKGQKRKLSGDQVEAGAPKNKKKKQQLAAGTSAGSPEKASRTSKAKSKLNKGSAGGKGKGSPVPQGAKEKPEGKLGIKLESGEQSDPKSKKEKKKSSKKKKDKEKKEKKKGKKTPAKDSASPVQKKKKKKKKTAEPAV", "length": 1357 }, "evidence": [ { "id": "E1BHU1", "url": "https://omabrowser.org/oma/group/E1BHU1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O08784-1", "protein_name": "Treacle protein", "gene_name": "Tcof1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEARKRRELLPLIYHHLLQAGYVRAAREVKEQSGQKSFLTQPVTLLDIYTHWQQTSELGQKQKAEDDETLQAKKSRVSDPVSSSESSDQEKEEEAATERAKATPRPTPVNSATAALPSKVKEKGKTKTANKTVNSVSHPGSGKTVVHLLSGKSPKKSAEPLANTVLASETEEEGNAQALGPTAKSGTVSAGQGSSSSEDSSISSDETDVEVKSPAKPAQAKASAAPAKDPPARTAPGPTKLGNVAPTPAKPARAAAAAAAAAVAAAAAAAAEESESSEEDSDSEDEAPAGLPSQVKASGKGPHVRADSVSAKGISGKGPILATPGKTGPAATQAKAERPEKDSETSSEDDSDSEDEMPVTVNTPQARTSGKSPRARGTSAPAKESSQKGAPAVTPGKARPVAAQAGKPEAKSSEESESDSGETPAAATLTTSPAKVKPLGKSSQVRPVSTVTPGSSGKGANLPCPGKVGSAALRVQMVKKEDVSESSSAELDSDGPGSPAKAKASLALPQKVRPVATQVKTDRGKGHSGSSEESSDSEEEAAPAASAAQAKPALEKQMKASSRKGTPASATGASTSSHCKAGAVTSSASLSSPALAKGTQRSDVDSSSESESEGAAPSTPRVQGKSGGKGLQGKAALGQGVAPVHTQKTGPSVKAMAQEDSESLEEDSSSEEEDETPAQATPLGRLPQAKANPPPTKTPPASASGKAVAAPTKGKPPVPNSTVSARGQRSVPAAGKAGAPATQAQKGPVAGTGEDSESSSKEESDSEEETPAQIKPVGKTSQVRAASAPAKESPKKGAHPGTPGKTGSSATQAQPGKTEDSDSSSEESDSDTEMPSAQAIKSPPVSVNRNSSPAVPAPTPEGVQAVNTTKKASGTTAQSSSSESEDGDEDLIPATQPSTYALRTSVTTPAALSRAASQPSKSEQSSRMPKGKKAKAAASAQTSSAVETLPMMPPQSAPIQPKATNKLGKSKLPEKQQLAPGYPKAPRSSEDSSDTSSEDEEDAKRPQMPKSAHRLDPDPSQKETVVEETPTESSEDEMVAPSQSLLSGYMTPGLTVANSQASKATPRPDSNSLASSAPATKDNPDGKQKSKSQHAADTALPKTGRKEASSGSTPQKPKKLKKSTSSSPAPTQTLPNSITQRLLEQAWPLSEAQVQASVVKVLTELLEQERLKATEAIKESGKKSQKRKLSGDLEAGAPKNKKKKEQPVPRASAVSPEKAPMTSKAKSKLDKGSAGGKGKGSPGPQGAKEKPDGELLGIKLESGEQSDPKSKSKKKKSLKKKKDKEKKEKKKGKKSLAKDSASPIQKKKKKKKKSAEPAV", "length": 1320 }, "evidence": [ { "id": "E1BHU1", "url": "https://omabrowser.org/oma/group/E1BHU1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q13428-1", "protein_name": "Treacle protein", "gene_name": "TCOF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV", "length": 1488 }, "evidence": [ { "id": "E1BHU1", "url": "https://omabrowser.org/oma/group/E1BHU1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "neural crest formation", "id": "GO:0014029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014029", "evidence": [ { "database": "UniProtKB", "id": "E1BHU1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "E1BHU1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" } ], "pmid": "" }, { "name": "neural crest cell development", "id": "GO:0014032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014032", "evidence": [ { "database": "UniProtKB", "id": "E1BHU1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" } ], "pmid": "" }, { "name": "nucleolar large rRNA transcription by RNA polymerase I", "id": "GO:0042790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042790", "evidence": [ { "database": "UniProtKB", "id": "E1BHU1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1BHU1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "E1BHU1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BHU1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "E1BHU1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" } ], "pmid": "" }, { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "E1BHU1", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1127, "end_pos": 1129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1266, "end_pos": 1268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHU1" }, { "id": "PF03546", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03546" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Treacle protein", "eco_id": "ECO_0000259", "start_pos": 253, "end_pos": 329, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 244, 261, 290, 675, 711, 949, 988, 1110, 1185, 1211 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1127, "end_pos": 1129 }, { "start_pos": 112, "end_pos": 114 }, { "start_pos": 1266, "end_pos": 1268 }, { "start_pos": 140, "end_pos": 142 }, { "start_pos": 727, "end_pos": 729 }, { "start_pos": 940, "end_pos": 942 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 10 }, { "field": "total_sites", "count": 10 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 10 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 10 }, { "field": "exact_o_linked_sites", "count": 10 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 10 }, { "field": "total_sites", "count": 10 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 10 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 10 }, { "field": "exact_o_linked_sites", "count": 10 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BE18-1", "uniprot_ac": "E1BE18", "uniprot_id": "E1BE18_BOVIN", "mass": { "chemical_mass": 92701.0, "monoisotopic_mass": 92701.0 }, "refseq": { "ac": "NP_001179505", "name": "zinc finger protein 341", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179505" }, "gene_names": [ { "name": "ZNF341", "type": "recommended", "evidence": [ { "id": "E1BE18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ] }, { "name": "ZFP341", "type": "synonym", "evidence": [ { "id": "NP_001179505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179505" } ] }, { "name": "ZNF341", "type": "synonym", "evidence": [ { "id": "NP_001179505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179505" } ] } ], "protein_names": [ { "name": "Zinc finger protein 341", "type": "synonym", "evidence": [ { "id": "E1BE18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE18/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 341", "type": "synonym", "evidence": [ { "id": "NP_001179505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179505" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF341", "url": "https://www.uniprot.org/uniprotkb/E1BE18", "locus": { "chromosome": "13", "start_pos": 63214476, "end_pos": 63174421, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000039313", "url": "https://www.ensembl.org/id/ENSBTAG00000039313" } ] } } ], "crossref": [ { "id": "E1BE18", "url": "https://alphafold.ebi.ac.uk/entry/E1BE18", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000039313", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039313", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "523204", "url": "https://www.ncbi.nlm.nih.gov/gene/523204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523204", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DGPCAML", "url": "https://omabrowser.org/oma/group/DGPCAML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LGS2", "url": "https://www.orthodb.org/?gene=A0A3Q1LGS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BE18", "url": "https://www.orthodb.org/?gene=E1BE18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21020:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21020:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24409:SF295", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24409:SF295", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179505", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179505", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LGS2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LGS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TX04", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TX04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TX04-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TX04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE18-1", "url": "https://www.uniprot.org/uniprotkb/E1BE18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQTIFEALEGMDNQTVLAVQSLLDGQGAVPDPTGQSVSAPPAIQPLDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGSALPLATVSLATNSIYTPSAAPSAIQQAPPPPNRQISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQPMPQGPQPVQSNLNMHPAPNYLAQPPPPPPPPPPLPPPPPPQPPPPPPQSLGPAGRPNPGGNGVVEVYNATAPLTGSGTVEIQALGMQPYPPLEVPNQCVEAPVYPTPQVYSPGKQGFKPKGPNPAAPMTSATGGTVASFDSPPSLKTRRTKGPSGLPEAAGKPKAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHKVWPPGRSGGTVSRNSVTVQVMALNPSRQEDEDNTGLGQTLSSAPQPQALPTAGEGEGDKLEAKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHSLLSQNSPKKDSAVYKCVKCVNKYSTPEALDHHLQTATHNFPCPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKDHRCRLGPQKDKDLQARRPPRRRAAPRSGSGGGHKVVTPLPDPLGLEELKDTGAGPMPEAAPGKPPFSEPDAVLSIVVGGTVGGEPELVVPGHAEGLGSNLALAELQAGAEGSCAMLAVPVYIQASE", "length": 854, "header": "tr|E1BE18-1|E1BE18_BOVIN Isoform 1 of Zinc finger protein 341 OS=Bos taurus OX=9913 GN=ZNF341 PE=4 SV=3 CANONICAL=E1BE18-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LGS2-1", "url": "https://www.uniprot.org/uniprotkb/E1BE18/entry#A0A3Q1LGS2-1", "sequence": { "sequence": "MAQTIFEALEGMDNQTVLAVQSLLDGQGAVPDPTGQSVSAPPAIQPLDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGSALPLATVSLATNSIYTPSAAPSAIQQAPPPPNRQISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQPMPQGPQPVQ", "length": 163, "header": "tr|A0A3Q1LGS2-1|E1BE18_BOVIN Computationally mapped isoform of Zinc finger protein 341 OS=Bos taurus OX=9913 GN=ZNF341 PE=4 SV=2 CANONICAL=E1BE18-1" }, "locus": { "chromosome": "13", "start_pos": 63185841, "end_pos": 63174497, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071242.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071242.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057733.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057733.2" } ] } }, { "isoform_ac": "A0AAA9TX04-1", "url": "https://www.uniprot.org/uniprotkb/E1BE18/entry#A0AAA9TX04-1", "sequence": { "sequence": "MAQTIFEALEGMDNQTVLAVQSLLDGQGAVPDPTGQSVSAPPAIQPLDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGSALPLATVSLATNSIYTPSAAPSAIQQAPPPPNRQISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQPMPQGPQPVQVPNQCVEAPVYPTPQVYSPGKQGFKPKGPNPAAPMTSATGGTVASFDSPPSLKTRRTKGPSGLPEAAGKPKAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHKVWPPGRSGGTVSRNSVTVQVMALNPSRQEDEDNTGLGQTLSSAPQPQALPTAGEGEGDKLEAKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHSLLSQNSPKKDSAVYKCVKCVNKYSTPEALDHHLQTATHNFPCPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKDHRCRLGPQKDKDLQARRPPRRRAAPRSGSGGGHKVVTPLPDPLGLEELKDTGAGPMPEAAPGKPPFSEPDAVLSIVVGGTVGGEPELVVPGHAEGLGSNLALAELQAGAEGSCAMLAVPVYIQASE", "length": 770, "header": "tr|A0AAA9TX04-1|E1BE18_BOVIN Computationally mapped isoform of Zinc finger protein 341 OS=Bos taurus OX=9913 GN=ZNF341 PE=4 SV=1 CANONICAL=E1BE18-1" }, "locus": { "chromosome": "13", "start_pos": 63213781, "end_pos": 63174497, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109062.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109062.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101996.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101996.1" } ] } }, { "isoform_ac": "E1BE18-1", "url": "https://www.uniprot.org/uniprotkb/E1BE18/entry#E1BE18-1", "sequence": { "sequence": "MAQTIFEALEGMDNQTVLAVQSLLDGQGAVPDPTGQSVSAPPAIQPLDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGSALPLATVSLATNSIYTPSAAPSAIQQAPPPPNRQISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQPMPQGPQPVQSNLNMHPAPNYLAQPPPPPPPPPPLPPPPPPQPPPPPPQSLGPAGRPNPGGNGVVEVYNATAPLTGSGTVEIQALGMQPYPPLEVPNQCVEAPVYPTPQVYSPGKQGFKPKGPNPAAPMTSATGGTVASFDSPPSLKTRRTKGPSGLPEAAGKPKAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHKVWPPGRSGGTVSRNSVTVQVMALNPSRQEDEDNTGLGQTLSSAPQPQALPTAGEGEGDKLEAKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHSLLSQNSPKKDSAVYKCVKCVNKYSTPEALDHHLQTATHNFPCPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKDHRCRLGPQKDKDLQARRPPRRRAAPRSGSGGGHKVVTPLPDPLGLEELKDTGAGPMPEAAPGKPPFSEPDAVLSIVVGGTVGGEPELVVPGHAEGLGSNLALAELQAGAEGSCAMLAVPVYIQASE", "length": 854, "header": "tr|E1BE18-1|E1BE18_BOVIN Isoform 1 of Zinc finger protein 341 OS=Bos taurus OX=9913 GN=ZNF341 PE=4 SV=3 CANONICAL=E1BE18-1" }, "locus": { "chromosome": "13", "start_pos": 63213781, "end_pos": 63174497, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061145.3", "url": "https://www.ensembl.org/id/ENSBTAT00000061145.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053666.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053666.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 260, "start_aa": "Thr", "end_pos": 260, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr260", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:523204", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523204", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZTX0-1", "protein_name": "Zinc finger protein 341", "gene_name": "ZNF341", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAQAIFEALEGMDNQTVLAVQSLLDGQGGVTDPSAQNVNAAAPMQPMDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAPSLSTVSLATNSVYTPSITSVQQAPSTSRQQISTYITVPPSPLIQTLVQGNILVSDEVLMSAMSAFTSLDQPMPAVQPPVQSSLSMHAGAGYLSQPPPPPPPPPPPPPQPPPPPPPSLGAPGQPSTGSGVVEVYSAPAPMAANSSVEIQALGMQPYPAMEVPSQCVESPVYPSPPVYSPGKQGFKPKSASVPTPLTSAGGGNVVGFDSTSAVKSRRSKSESGLQEGKPKSPKLKCTYCDKAFTKNFDLQQHIRSHTGEKPFQCIVCGRAFAQKSNVKKHMQTHKVWPPGLGCTISRNSITVQVMALNPNQVEDEENTGLTQPSRNPAQPPQDMSPMDESDAGKLEAKQVVLIDSSYQCQFCPSKFNTYFQLKSHMTQHKNEQVYKCVVKSCAQTFQKLESFLDHIKSHQEELSYRCHLCSKDFPSLYELGVHQYSHSLLPQHSPKKDVAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHCQKVFPCERYLRRHIPTHGGGSKFKCQICKKFFRREHYLKLHAHIHSGEKPFKCSVCDAAFNRKDKLKRHMLIHEPFKKYKCPFSSHTGCNKEFNRPDKLKAHILSHSGMKIHKCQYCNKSFSRRAHMIEHQRSHTGNYKYRCPTCSKGFTRHKYMKDHKCRLGSPKDKDLQLRKPQKKRVVRGRKVGLSLPNQLALGELKDSVGGESPQEGVPNKEPFQESDAVLSIVVGGSGAADSDLVVPGQPSSIASNLSLAELQAASDGPCTMLAVPVYIQTTE", "length": 840 }, "evidence": [ { "id": "E1BE18", "url": "https://omabrowser.org/oma/group/E1BE18/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F7ETL6-1", "protein_name": "Zinc finger protein 341", "gene_name": "Zfp341", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQAIFEALEGMDNQTVLAVQSLLDGQGAVPDPTGQGVSAPPAIQPLDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAPALATVSLATNSIYTPSAAPAAVQQAPPPANRQISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQPMPQGPSPVQNSLNMHPVPNYLTQPPPPPPPPPPLPPPPQPPPPPPQTLGPSGRSNPVGNSVVEVYSAAAPMAGNGTVDIQALGMQPYPPLEVPNQCVEAPVYPTPPVYSPGKQEFKPKGPNSTAPMTSATGSTVATFDPPPTLKTRRAKGASGLPEAAGKPKAQKLKCSYCDKSFTKNFDLQQHVRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHKVWPPGRSGGTVSRNSVTVQVMALNPNRQEEEDTGLGQSLSSTTQPQALPTAGEEEGNKPEAKQVVLIDSSYLCQFCPSKFSTYFQLKSHMIQHKKEQVYKCVVKSCAQMFPKLDTFLEHIRSHQEELSYRCHLCSKDFPSLYDLGVHQYSHSLLPQHSPRKDSTVYKCVKCVNKYSTPEALEHHVQTATHSFPCPHCQKVFPCERYLRRHLPTHGSGGRFRCQICKKFFRKEHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSMHTGCSKEFNRQDKLKAHILSHAGLKLHKCGLCSKSFSRRAHLAEHQHAHTGNYKFRCAGCAKGFSRHKYLKDHRCRLGPSKDKDLQTRRPPRRRATARGAGNIASVHKEENPLPDPLGLEELKAAGPSPEAAPGKPPFEQDAVLSIVVGGDPELVVPGHTEGLGSNLALAELQAGTEGGCAMLAVPVYIQASE", "length": 846 }, "evidence": [ { "id": "E1BE18", "url": "https://omabrowser.org/oma/group/E1BE18/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BYN7-1", "protein_name": "Zinc finger protein 341", "gene_name": "ZNF341", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQAIFEALEGMDNQTVLAVQSLLDGQGAVPDPTGQSVNAPPAIQPLDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAPALATVSLATNSIYPPSAAPTAVQQAPTPANRQISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQPMPQGPPPVQSSLNMHSVPSYLTQPPPPPPPPPPLPPPPPPQPPPPPPQSLGPPGRPNPGGNGVVEVYSAAAPLAGSGTVEIQALGMQPYPPLEVPNQCVEPPVYPTPTVYSPGKQGFKPKGPNPAAPMTSATGGTVATFDSPATLKTRRAKGARGLPEAAGKPKAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHKVWPPGHSGGTVSRNSVTVQVMALNPSRQEDEESTGLGQPLPGAPQPQALSTAGEEEGDKPESKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHSLLPQHSPKKDNAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKDHRCRLGPQKDKDLQTRRPPQRRAAPRSCGSGGRKVLTPLPDPLGLEELKDTGAGLVPEAVPGKPPFAEPDAVLSIVVGGAVGAETELVVPGHAEGLGSNLALAELQAGAEGPCAMLAVPVYIQASE", "length": 854 }, "evidence": [ { "id": "E1BE18", "url": "https://omabrowser.org/oma/group/E1BE18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity", "id": "GO:0001216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001216", "evidence": [ { "database": "UniProtKB", "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BE18", "url": "https://www.uniprot.org/uniprotkb/E1BE18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BE18-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 854, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BE18-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BE18" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BE18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE18" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 322, "end_pos": 349, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 260 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 222, "end_pos": 224 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDW9-1", "uniprot_ac": "E1BDW9", "uniprot_id": "E1BDW9_BOVIN", "mass": { "chemical_mass": 103343.0, "monoisotopic_mass": 103343.0 }, "refseq": { "ac": "NP_001193088", "name": "exocyst complex component 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193088" }, "gene_names": [ { "name": "EXOC2", "type": "recommended", "evidence": [ { "id": "E1BDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDW9" } ] }, { "name": "EXOC2", "type": "synonym", "evidence": [ { "id": "NP_001193088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193088" } ] } ], "protein_names": [ { "name": "Exocyst complex component 2", "type": "recommended", "evidence": [ { "id": "E1BDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDW9/entry#names_and_taxonomy" } ] }, { "name": "exocyst complex component 2", "type": "synonym", "evidence": [ { "id": "NP_001193088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193088" } ] } ], "function": [ { "annotation": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL76", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL76#function" }, { "database": "UniProtKB", "id": "RU365069", "url": "https://www.uniprot.org/uniprotkb/RU365069#function" }, { "database": "UniProtKB", "id": "ARBA00002660", "url": "https://www.uniprot.org/uniprotkb/ARBA00002660#function" }, { "database": "UniProtKB", "id": "A0AAA9S5C4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5C4#function" }, { "database": "UniProtKB", "id": "A0AAA9SE22", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE22#function" }, { "database": "UniProtKB", "id": "E1BDW9", "url": "https://www.uniprot.org/uniprotkb/E1BDW9#function" }, { "database": "UniProtKB", "id": "A0AAA9TNU9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDW9", "url": "https://www.uniprot.org/uniprotkb/E1BDW9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EXOC2", "url": "https://www.uniprot.org/uniprotkb/E1BDW9", "locus": { "chromosome": "23", "start_pos": 52169676, "end_pos": 52071554, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020215", "url": "https://www.ensembl.org/id/ENSBTAG00000020215" } ] } } ], "crossref": [ { "id": "E1BDW9", "url": "https://alphafold.ebi.ac.uk/entry/E1BDW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020215", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020215", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00603", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00603", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513431", "url": "https://www.ncbi.nlm.nih.gov/gene/513431", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039481", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039481", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513431", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513431", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMWMDVD", "url": "https://omabrowser.org/oma/group/RMWMDVD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BDW9", "url": "https://www.orthodb.org/?gene=E1BDW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13043:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13043:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-264876", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-264876", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5620916", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193088", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193088", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LL76", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LL76-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5C4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5C4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SE22", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SE22-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNU9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNU9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDW9", "url": "https://www.uniprot.org/uniprotkb/E1BDW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDW9-1", "url": "https://www.uniprot.org/uniprotkb/E1BDW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPADLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGKFPQKDLEMLFPGMSADFTSENFSAAWYLIENHSNTSFEQLKMAITHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLEKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHRWILQLMHGCREGCVRDLKGPPGLHSTSLDLDAEVRASAPSHLGQTASLKRGSSFQPGRDDAWRCKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQNDFKKMIQEVMQCLVKLVRGALLPLGAAEGSGRQLGGWEGKAELSGPWLAHVIQTLRLTYESLAALEIPNDLLQTIQDLVLDLRVRCVLVTLQHTAEDIKRLAEKEDWVVDSEGLTSLPCRFERCVVLSLQSLRGVLECKPGEASVFQHPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADVDTAHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFESYIELKADPIVGSLEPGIYAGYFDWRDCLPPTGVRNYLKEALVNIIAVHAEVFTVSKDLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICTLRDTVAAHLTLESRSSFKQALEALPQLSSGADRKLLEELLSRVKSGMHLQLACFQAAPPPAVKT", "length": 924, "header": "tr|E1BDW9-1|E1BDW9_BOVIN Isoform 1 of Exocyst complex component 2 OS=Bos taurus OX=9913 GN=EXOC2 PE=3 SV=1 CANONICAL=E1BDW9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LL76-1", "url": "https://www.uniprot.org/uniprotkb/E1BDW9/entry#A0A3Q1LL76-1", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPADLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGKFPQKDLEMLFPGMSADFTSENFSAAWYLIENHSNTSFEQLKMAITHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLEKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHRWILQLMHGCREGCVRDLKGPPGLHSTSLDLDAEVRASAPSHLGQTASLKRGSSFQPGRDDAWRCKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQNDFKKMIQEVMQCLVKLVRGALLPLGAAEGSGRQLGGWEGKAELSGPWLAHVIQTLRLTYESLAALEIPNDLLQTIQDLVLDLRVRCVLVTLQHTAEDIKRLAEKEDWVVDSEGLTSLPCRFERCVVLSLQSLRGVLECKPGEASVFQHPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADVDTAHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFESYIELKADPIVGSLEPGIYAGYFDWRDCLPPTGVRNYLKEALVNIIAVHAEVFTVSKDLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQAAGGAAEPGQEWHAPAAGLLPGCPPTRREDVEPPGDAR", "length": 891, "header": "tr|A0A3Q1LL76-1|E1BDW9_BOVIN Computationally mapped isoform of Exocyst complex component 2 OS=Bos taurus OX=9913 GN=EXOC2 PE=3 SV=1 CANONICAL=E1BDW9-1" }, "locus": { "chromosome": "23", "start_pos": 52168583, "end_pos": 52071596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070275.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070275.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057225.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057225.2" } ] } }, { "isoform_ac": "A0AAA9S5C4-1", "url": "https://www.uniprot.org/uniprotkb/E1BDW9/entry#A0AAA9S5C4-1", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPADLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGKFPQKDLEMLFPGMSADFTSENFSAAWYLIENHSNTSFEQLKMAITHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLEKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHRWILQLMHGCREGCVRDLKAWRCKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQNDFKKMIQEVMQCLVKLVRGALLPLGAAEGSGRQLGGWEGKAELSGPWLAHVIQTLRLTYESLAALEIPNDLLQTIQDLVLDLRVRCVLVTLQHTAEDIKRLAEKEDWVVDSEGLTSLPCRFERCVVLSLQSLRGVLECKPGEASVFQHPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADVDTAHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFESYIELKADPIVGSLEPGIYAGYFDWRDCLPPTGVRNYLKEALVNIIAVHAEVFTVSKDLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICTLRDTVAAHLTLESRSSFKQALEALPQLSSGADRKLLEELLSRVKSGMHLQLACFQAAPPPAVKT", "length": 882, "header": "tr|A0AAA9S5C4-1|E1BDW9_BOVIN Computationally mapped isoform of Exocyst complex component 2 OS=Bos taurus OX=9913 GN=EXOC2 PE=3 SV=1 CANONICAL=E1BDW9-1" }, "locus": { "chromosome": "23", "start_pos": 52168560, "end_pos": 52071596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101659.2", "url": "https://www.ensembl.org/id/ENSBTAT00000101659.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081145.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081145.1" } ] } }, { "isoform_ac": "A0AAA9SE22-1", "url": "https://www.uniprot.org/uniprotkb/E1BDW9/entry#A0AAA9SE22-1", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPADLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGKFPQKDLEMLFPGMSADFTSENFSAAWYLIENHSNTSFEQLKMAITHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLEKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHRWILQLMHGCREGCVRDLKGPPGLHSTSLDLDAEVRASAPSHLGQTASLKRGSSFQPGRDDAWRCKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQNDFKKMIQEVMQCLVKLVRGALLPLGAAEGSGRQLGGWEGKAELSGPWLAHVIQTLRLTYESLAALEIPNDLLQTIQDLVLDLRVRCVLVTLQHTAEDIKRLAEKEDWVVDSEGLTSLPCRFERCVVLSLQSLRGVLECKPGEASVFQHPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADVDTAHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFESYIELKADPIVGSLEPGIYAGYFDWRDCLPPTGVRNYLKEALVNIIAVHAEVFTVSKDLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQIQFQAGPGSPASALERSRQKAAGGAAEPGQEWHAPAAGLLPGCPPTRREDVEPPGDAR", "length": 911, "header": "tr|A0AAA9SE22-1|E1BDW9_BOVIN Computationally mapped isoform of Exocyst complex component 2 OS=Bos taurus OX=9913 GN=EXOC2 PE=3 SV=1 CANONICAL=E1BDW9-1" }, "locus": { "chromosome": "23", "start_pos": 52168583, "end_pos": 52071596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100596.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100596.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081838.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081838.1" } ] } }, { "isoform_ac": "A0AAA9TNU9-1", "url": "https://www.uniprot.org/uniprotkb/E1BDW9/entry#A0AAA9TNU9-1", "sequence": { "sequence": "MTNLDSILKNGGHHFADKGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGKFPQKDLEMLFPGMSADFTSENFSAAWYLIENHSNTSFEQLKMAITHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLEKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHRWILQLMHGCREGCVRDLKGPPGLHSTSLDLDAEVRASAPSHLGQTASLKRGSSFQPGRDDAWRCKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQNDFKKMIQEVMQCLVKLVRGALLPLGAAEGSGRQLGGWEGKAELSGPWLAHVIQTLRLTYESLAALEIPNDLLQTIQDLVLDLRVRCVLVTLQHTAEDIKRLAEKEDWVVDSEGLTSLPCRFERCVVLSLQSLRGVLECKPGEASVFQHPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADVDTAHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFESYIELKADPIVGSLEPGIYAGYFDWRDCLPPTGVRNYLKEALVNIIAVHAEVFTVSKDLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICTLRDTVAAHLTLESRSSFKQALEALPQLSSGADRKLLEELLSRVKSGMHLQLACFQAAPPPAVKT", "length": 903, "header": "tr|A0AAA9TNU9-1|E1BDW9_BOVIN Computationally mapped isoform of Exocyst complex component 2 OS=Bos taurus OX=9913 GN=EXOC2 PE=3 SV=1 CANONICAL=E1BDW9-1" }, "locus": { "chromosome": "23", "start_pos": 52168560, "end_pos": 52072672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120506.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120506.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100246.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100246.1" } ] } }, { "isoform_ac": "E1BDW9-1", "url": "https://www.uniprot.org/uniprotkb/E1BDW9/entry#E1BDW9-1", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPADLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGKFPQKDLEMLFPGMSADFTSENFSAAWYLIENHSNTSFEQLKMAITHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLEKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHRWILQLMHGCREGCVRDLKGPPGLHSTSLDLDAEVRASAPSHLGQTASLKRGSSFQPGRDDAWRCKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQNDFKKMIQEVMQCLVKLVRGALLPLGAAEGSGRQLGGWEGKAELSGPWLAHVIQTLRLTYESLAALEIPNDLLQTIQDLVLDLRVRCVLVTLQHTAEDIKRLAEKEDWVVDSEGLTSLPCRFERCVVLSLQSLRGVLECKPGEASVFQHPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADVDTAHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFESYIELKADPIVGSLEPGIYAGYFDWRDCLPPTGVRNYLKEALVNIIAVHAEVFTVSKDLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICTLRDTVAAHLTLESRSSFKQALEALPQLSSGADRKLLEELLSRVKSGMHLQLACFQAAPPPAVKT", "length": 924, "header": "tr|E1BDW9-1|E1BDW9_BOVIN Isoform 1 of Exocyst complex component 2 OS=Bos taurus OX=9913 GN=EXOC2 PE=3 SV=1 CANONICAL=E1BDW9-1" }, "locus": { "chromosome": "23", "start_pos": 52168560, "end_pos": 52071596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026920.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026920.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026920.3", "url": "https://www.ensembl.org/id/ENSBTAP00000026920.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:513431", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513431", "resource": "KEGG Pathway" }, { "id": "R-BTA-264876", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-264876", "resource": "Reactome", "description": "Insulin processing" }, { "id": "R-BTA-5620916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620916", "resource": "Reactome", "description": "VxPx cargo-targeting to cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "F1P2A7-1", "protein_name": "Exocyst complex component 2", "gene_name": "EXOC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRARQPPLVTGISPNEGISWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIDKGRFPQKDLETLFPGMSADFTSENFSAAWYLIENHSTASFDQLKMAVVNLKKQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHQWILQLMHNCKESYVKEQKGTSLLHSSMLDLDSDVRPSPIGHLSQTASLKRGSSFQSGRNDAWRYKAPQQVVFVEKLTKLVVSQLPNFWKLWISYVNGSLFSETAEKSGQMEKSKKNARQRQNDFKKMIQEVMHSLEKLIRGALLPFSLKEGESRQYGGWEMKSELSGQWLTHVIQTVRLSSESLTALEIPNDMLQIIQDLILDLRVRCIIVTLQHTAEDIKRLAEKEDWVVDNEGLTSLPSHFEQCIVHSLQSLKTVLDCKPGEASVFQQQKIQEDVCQLSIGILQVFIDCLEQLSTKPDGDIDTSHLSVDVSSPDLFGSIHEDSSLTSEQRVLIALSNCRYLERHTFLNIAEHFEKHGFQGVDKITQVSMESLKELDQRLFEMYIESKADPIVGSLEPGIYAGYFDWKDCLVPAGVRNYLKEALVNIIAVHAEVFTISKDLVPRVMSRIVEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAIYLTPESNSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQTSSSAMIKT", "length": 925 }, "evidence": [ { "id": "E1BDW9", "url": "https://omabrowser.org/oma/group/E1BDW9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RXP8-1", "protein_name": "Exocyst complex component 2", "gene_name": "EXOC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRSRPPPLVTGISPNEGIPWTKVTIRGENLGTGTPDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGVLDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGQFPQKDLEVLFPGMSADFTSENLSAAWYLIENHSNTSFEQLKMAVAHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALTVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLRAPGDPAWQCIGAQHRWILQLMHDCREGCARDLTGTSGLHSAVSDPDSDARPPALGHLGHTASLKRGSGFQSGRGDAWRYKTPQRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQSDFKKMIQEVMHCLVKLIRGALLPPSAAEGGVRPGTGREVKAELSGQWLAHVIQTLRLTYESLTALEIPSDLLQTIQDLVLDLRGRCVAATLQHTAEEIKRLAEKEDWVVDSEGLTSLPCQFERRVVQSLQSLRGVLECRPGEASVFQQPKTQEEVCQLSINIMQIFICCLEQLSTKPDADVDTAHLSVDVASPDLFGSIHQELSLTPEQRLLIVLSNCCYLERHTFRNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVSIIAVHAEVFAVCKGLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDILAAHLTPESRSSFKQALEALPQLSSGAERTSSHQCSLKAEKRRTRGTGNRPAVAWGGGRAKAAGRTAEPGQRQHAPAAGLLPGCPTACCEDLGVPPCCACPRPQCSRRQASV", "length": 976 }, "evidence": [ { "id": "E1BDW9", "url": "https://omabrowser.org/oma/group/E1BDW9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O54921-1", "protein_name": "Exocyst complex component 2", "gene_name": "Exoc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKCKLPQKNLEVLFHGMSADFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMKSLKGNPGPHSPMLDLDNDARPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLIRGALLPFSLREGDGRQYGGWEVQAELSGQWLAHVIQTIRLTYESLTALEIPNDMLQIIQDLILDLRIHCIMVTLQHTAEEIKRLAEKEDWIVDNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPKTQEEVCQLCISIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFGLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLETGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVIEAVSEELSRLMQCVSSFSRNGALQARLEICALRDTVAIYLTPESRSSFKQALEALPQLASGADKKLLEELLNKFKSSMHLQLTCFQAASPTVMKT", "length": 924 }, "evidence": [ { "id": "E1BDW9", "url": "https://omabrowser.org/oma/group/E1BDW9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P89102-1", "protein_name": "Exocyst complex component SEC5", "gene_name": "SEC5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDRFQIGDEQLLRFYQLKTINPTHSWAQDSSKLNNEEATSNELGVETSFDILKDFKYGNQISIDKESRAYLNDESLSYIRDPLNGQEMSKELQHLPNDSMRLNYLVNSKQFNVKAFLRDMHKQDSFNDLNNSLDRLDSDIQDQSIHLKQLVGKNFTKYVKIKNKLDQIYKEFDEKTNEKNQCDSPKENQINVESLNKKVDEVIRTTTFKLKPLMDNYQKILNYQATKKFIELNKFYFNLPKSLKRCLTNNDFNEFIIEYSKGLTLRRRFNQSSDASQSLVIKRIWTQIENLLVTYKDLIWNSLINSNFNIDQPQETILSLFSKLLNLENFINNNQRESESGNKNTTSSSNENPILRWMSIKMNGFQNELNELSGHMISKIIHSQRLILQNNTNQDKSQGCVELSYYLKINQLFQIISDTGKDSEGLKSTVEPNKVNTISGTSYLNLNCQPSSQGLTDSPTIIEMWLLILKYINDLWKICDQFIEFWEHIEKFLDGTYQNSIINEKRKENILIGDSNIIESYQKSLILKEEQINEVRLKGEEFITSVSQNLISFFTSSQSSLPSSLKDSTGDITRSNKDSGSPLDYGFIPPNCNGLSCLRYLPKIVEPILKFSTELAQLNITTNGITICRNTLSTIINRCVGAISSTKLRDISNFYQLENWQVYETVTFSSKSQDSSKNLTFEYGVTQFPEIVTSFQEVSIKTTRDLLFAYEKLPIINGISVVSYPSKQLLTGIEIQQIISMEAVLEAILKNAAKDKDNPRNSHTILTLTNLQYFRECAFPNILQYFDDAFEWNLASKNLELFSLLSKMESSIFGNYLSDLKINLRDTLEEKFHEINWPMYTSNSFRVGDYIIEALMILIVVHSECFRIGPQLIHKILIETQIFIARYLFEAFKPYVGNLSNDGSLQIIVDLEFFQKVMGPLLEKDTEATLRACLQNCFQNDTNRLQKCINEINPIVSANLKRTAIQFAAFS", "length": 971 }, "evidence": [ { "id": "E1BDW9", "url": "https://omabrowser.org/oma/group/E1BDW9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8S3U9-1", "protein_name": "Exocyst complex component SEC5A", "gene_name": "SEC5A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDSNDLDEDELLQMALKEQAKRDLTYQKPPSSSARKPVANLVQQPRQQKPVAAAAAPPKKSAAAVRKPSMDEDEESEVELLSISSGDDDLEREREIGGSSGGAGRGRGSDVREKGRARKEDDGAWDGGEPDCWKRVNEAELARRVRDMRESRTAPVVQKVEGKAPAPGKKVALTSLQSLPRGMECIDPLKLGIIDNKTLRLITESSGSPSKAEKVDNTLREKLVYFSDHFDPKLFLSRIHQDTTAADLEAGALGLKSDLKGRNLQRKQLVKDNFDCFVSCKTTIDDIESKLKRIEEDPEGSGTTHLFNCMKSVTSRANLAFEPLFERQAQAEKIRSVQGMLQRFRTLFNLPSIIRSSISKGEYDLAVREYKKAKSIALPSHVNILKRVLEEVEKVMLEFKGTLYKSMEDPKIDFTSLENTVRLLLELEPESDPVWHYLNVQNHRIHGLLEKCTYDHEARVEILRNDTHEKAISDAKWQQIQQNGVSYSDTASSNENNAVQVDLQSVEFPSEEIDILKGRYIKRLTAVLVHHIPVFWKTAISIFSGKFAKSSQVTDTSANKAEEKVTEARYSTHSLEEVAGMIRKTISVYEAKVNSTFCDFDESCILRPFMSDAINEVSKACQAFEAKESTPHSAVVALRKIQAEITKIYIQRLCSWMRASTEGISKEETWIPVSILERNRSPYAISYLPLAFRSVIVSGMEQVNLMILSVKSEAAKSEDMFAQIEEIIISVRLAFLNCFLDFAAHLEQIGADLSQSTSRQDNWKNGYSDEHQEEPSANTYGSVIDPHRRLLMVLSNIGYCKDELASELYNKFKYTWLQSRDKNEDSSDLQDLIMSFSGLGEKVLEHYTFAKANLIRTAATNYLLDSGIQWGSAPQVKGIRDAAVELLHTLVAVHAEVFAGAKPLLDKILGVLIEGLIDTFLSVVEENRSSDLRSIDANGFCQLMFELEYFETVLYSYFTSAATESLKSLQGTVLEIAIESISEAVETPGHNRRPTRGSEDTVSDDKQSVSADDLLALTKQCSNELLQQELERTRVNTACFAESAPLESTPPLPKATYSSFRGSMDSPSRNYRGSQSSGSPINARPRRR", "length": 1090 }, "evidence": [ { "id": "E1BDW9", "url": "https://omabrowser.org/oma/group/E1BDW9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96KP1-1", "protein_name": "Exocyst complex component 2", "gene_name": "EXOC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKSKFSQKDLEMLFHGMSADFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVKCELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKRLAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQAASSTMMKT", "length": 924 }, "evidence": [ { "id": "E1BDW9", "url": "https://omabrowser.org/oma/group/E1BDW9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4H1-1", "protein_name": "Exocyst complex component 2", "gene_name": "Exoc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKCKLPQKNLEVLFHGMSADFTSENFSAAWYLIENHSTTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMKSLKGHPGPHSPMLDLDNDVRPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQSERSKNVRQRQNDFKKMIQEVMHSLVKLIRGALLPLSLREGDGRQYGGWEVQAELSGQWLAHVIQTIRLTYESLTALEIPNDMLQIIQDLILDLRIRCIMVTLQHTAEEIKRLAEKEDWVVDNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPKTQEEVCQLCINIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDTVAIYLTSESRSSFKQALEALPQLASGADKKSLEELLNKFKSSMHLQLTCFQAASPAVMKT", "length": 924 }, "evidence": [ { "id": "E1BDW9", "url": "https://omabrowser.org/oma/group/E1BDW9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VQQ9-1", "protein_name": "Exocyst complex component 2", "gene_name": "Sec5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAPQPVVTGLSPKEGPPGTRVIIRGEFLGTRVQDLIGLKICGSDCLLSAEWKSPNKIIARTGPAKGKGDIIVTTLSGGVGTSTVQFRAYHETIGPLKESAVWIEESPSQNFAWGRRTLAQSGLTQEDPLGLSIEGNEQKIPEDLRDLFPEACGDLSQEHFSPAWFLLENHLATSFEDLKAGLSYLKRKVESQKEGQLSFLKSNAGSVIDQLDTLMNIRDKLQEDVKLHGNETLNILETSIENSISESQKIFTDVLVRKEKADSTRSVLFALSRHKFLFCLPNSVDRRAKAGEYDIVVNDYSRAKNLFGKTEIPIFRKVLEEVDHRILSIRKQLHEKVVKMPQSVEQQKKLIKALISLELQQSGTPIGDKLRNIDPAWDAIEARAKYLEWTFRQTFDQHTSKDSGAQEKAKNRDSSQAPNRVNFCEELCDIAASQLPDLWRLGQLYFTGELRGPHDPKPGDFKRMVLNAIEKFCVYLRLAILIATDQRALRQSSGLAWPIGSASATHQFLPWIPQCLRFTRIAYATLISLDLPSEALDIIQKLIDEVRLFCFSIIFKRATDRCKKLGSQETWELGVEEYPGATLLPAALETLLIETLDEVQSVCMQRETREGNLLEPQSDGQREVTQRLQEFLSAFSAVIEELAFHSHDEETPTHNVSQLLGFPNAQQPDSVAGSGGAAAVTWEQRMLCCLANYAYCNKIFFPRLGDIFVRYGYPLPTLAIETARYTVNQLFTNLLEEYVEHKGDPLVGTIEPSMYLGRFQWDHEMEIGQLRPYAHECCDNLVGVYSEIYSISPALLRPILESIVQTISEELARLMSCVQRFSFTGAIQAHVDIRLLRDSLEGYVNETAKNYFMEALEAINPPLSGEQKRKADEILERVKRNMRLQLLCFSVKDP", "length": 894 }, "evidence": [ { "id": "E1BDW9", "url": "https://omabrowser.org/oma/group/E1BDW9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "E1BDW9", "url": "https://www.uniprot.org/uniprotkb/E1BDW9" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "E1BDW9", "url": "https://www.uniprot.org/uniprotkb/E1BDW9" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "E1BDW9", "url": "https://www.uniprot.org/uniprotkb/E1BDW9" } ], "pmid": "" }, { "name": "regulation of entry of bacterium into host cell", "id": "GO:2000535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000535", "evidence": [ { "database": "UniProtKB", "id": "E1BDW9", "url": "https://www.uniprot.org/uniprotkb/E1BDW9" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "E1BDW9", "url": "https://www.uniprot.org/uniprotkb/E1BDW9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "E1BDW9", "url": "https://www.uniprot.org/uniprotkb/E1BDW9" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "E1BDW9", "url": "https://www.uniprot.org/uniprotkb/E1BDW9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, 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166 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 475, "end_pos": 477 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"id": "618637", "url": "https://www.ncbi.nlm.nih.gov/gene/618637", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618637", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618637", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACTVNEC", "url": "https://omabrowser.org/oma/group/ACTVNEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LME7", "url": "https://www.orthodb.org/?gene=A0A3Q1LME7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BKW8", "url": "https://www.orthodb.org/?gene=E1BKW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002696253", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696253", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LME7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LME7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LME7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LME7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKW8-1", "url": "https://www.uniprot.org/uniprotkb/E1BKW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAQQLEDKLTCSICLELYKEPVTLLCGHNFCGACIRDWWGLCEKVCPECREPFPDGAELRRNVALSGVVEELRATPGPGPDPSHGARCPRHGQPLELFCRTEGLCVCCVCTVRECRLHERVLLDAERRAREAQLRATLEVTQQQAAQAQRQLQELQQRSSQIQNSACTLTSVISGKFSCLLQALEMRRVRALRDINVAKTQALEQAQQEKQRLQGHLEAVSFCDRRIRHLLEHLDDWTFLQESQQLVPPGPLGPLTLPQWDEDQQLGGLKESLSQLCALLLEEGAHSGVPTEAADLGSVESPGPLAPVLSPVCPLRRRLWQNYRNLTFDPVSANRHLYLSQQDQRVKHLLKPRGPDGPGSFELWQVQCAQSFQAGQHYWEVRASSHSVTLGVAYSELTRRRQGPHTDNIGRGPSSWGLCIQEDCTQAWHDGKAQRLPVVSGRLLGVDLNLASGCLTFYSLEPKTQPLHTFHAIFTRPLYPIFWLLEGRTLTLCHQPEATLPPGLQEEASGLSGGRQGTSATPVARCHHSHGPQNRPSCSPGDLRPQL", "length": 548, "header": "tr|E1BKW8-1|E1BKW8_BOVIN Isoform 1 of E3 ubiquitin-protein ligase TRIM65 OS=Bos taurus OX=9913 GN=TRIM65 PE=3 SV=3 CANONICAL=E1BKW8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LME7-1", "url": "https://www.uniprot.org/uniprotkb/E1BKW8/entry#A0A3Q1LME7-1", "sequence": { "sequence": "MAAQQLEDKLTCSICLELYKEPVTLLCGHNFCGACIRDWWGLCEKVCPECREPFPDGAELRRNVALSGVVEELRATPGPGPDPSHGARCPRHGQPLELFCRTEGLCVCCVCTVRECRLHERVLLDAERRAREAQLRATLEVTQQQAAQAQRQLQELQQRSSQIQNSACTLTSVISGKFSCLLQALEMRRVRALRDINVAKTQALEQAQQEKQRLQGHLEAVSFCDRRIRHLLEHLDDWTFLQESQQLVPPGPLGPLTLPQWDEDQQLGGLKESLSQLCALLLEEGAHSGVPTEAADLGSVDYRNLTFDPVSANRHLYLSQQDQRVKHLLKPRGPDGPGSFELWQVQCAQSFQAGQHYWEVRASSHSVTLGVAYSELTRRRQGPHTDNIGRGPSSWGLCIQEDCTQAWHDGKAQRLPVVSGRLLGVDLNLASGCLTFYSLEPKTQPLHTFHAIFTRPLYPIFWLLEGRTLTLCHQPEATLPPGLQEEASGLSGGRQGTSATPVARCHHSHGPQNRPSCSPGDLRPQL", "length": 526, "header": "tr|A0A3Q1LME7-1|E1BKW8_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM65 OS=Bos taurus OX=9913 GN=TRIM65 PE=3 SV=1 CANONICAL=E1BKW8-1" }, "locus": { "chromosome": "19", "start_pos": 55731300, "end_pos": 55727639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073528.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073528.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057843.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057843.1" } ] } }, { "isoform_ac": "E1BKW8-1", "url": "https://www.uniprot.org/uniprotkb/E1BKW8/entry#E1BKW8-1", "sequence": { "sequence": "MAAQQLEDKLTCSICLELYKEPVTLLCGHNFCGACIRDWWGLCEKVCPECREPFPDGAELRRNVALSGVVEELRATPGPGPDPSHGARCPRHGQPLELFCRTEGLCVCCVCTVRECRLHERVLLDAERRAREAQLRATLEVTQQQAAQAQRQLQELQQRSSQIQNSACTLTSVISGKFSCLLQALEMRRVRALRDINVAKTQALEQAQQEKQRLQGHLEAVSFCDRRIRHLLEHLDDWTFLQESQQLVPPGPLGPLTLPQWDEDQQLGGLKESLSQLCALLLEEGAHSGVPTEAADLGSVESPGPLAPVLSPVCPLRRRLWQNYRNLTFDPVSANRHLYLSQQDQRVKHLLKPRGPDGPGSFELWQVQCAQSFQAGQHYWEVRASSHSVTLGVAYSELTRRRQGPHTDNIGRGPSSWGLCIQEDCTQAWHDGKAQRLPVVSGRLLGVDLNLASGCLTFYSLEPKTQPLHTFHAIFTRPLYPIFWLLEGRTLTLCHQPEATLPPGLQEEASGLSGGRQGTSATPVARCHHSHGPQNRPSCSPGDLRPQL", "length": 548, "header": "tr|E1BKW8-1|E1BKW8_BOVIN Isoform 1 of E3 ubiquitin-protein ligase TRIM65 OS=Bos taurus OX=9913 GN=TRIM65 PE=3 SV=3 CANONICAL=E1BKW8-1" }, "locus": { "chromosome": "19", "start_pos": 55731300, "end_pos": 55727639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029353.8", "url": "https://www.ensembl.org/id/ENSBTAT00000029353.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029353.6", "url": "https://www.ensembl.org/id/ENSBTAP00000029353.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:618637", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618637", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZY16-1", "protein_name": "E3 ubiquitin-protein ligase TRIM65", "gene_name": "Trim65", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSCPGRPEGAAPQLPVRQKPDKGDLDPCQGTFRGTRAQRSRCPCALPSSWTVLRPSVASVPLRGLRTQDLASAMAVQLLEEDLVTCPICLGRYCDPVTLPCGHTFCGNCIQDSWRCCEKICPECRQPFPEGAKLSRNVKLSTLLQGLPAAIQRLESGTSQSARCPRHGRPLEFFCLTEGLCVCSACTVHDCSHHERALLDVERRVREDRLRARVMVTRQQATQAETQLEELQQQSSQIESSARTLASVVSRRFSSLLQVLEKQQASTLSDIEGAKKRALDQVLHERQRLTDHLKALSQYDQSVQDLLGQGDDFIFFQGLQQLSEPIGSLGPPTPPQWDEEEQLNSVNQLLSPLCELLLEEKTLPTAADKAASAGPMEALGPLAPVPSAMCPLRKKLWQNYRNLTFDPETANRYLLLSHKAQQVTHHFQAQSPARSGSFELWQVQCTQSFQTGQHYWEVRASDHSITLGVTYPELPRRKLGTHTDNIGRGPYSWGLCIQEDSIQAWHNGRAQRLSRAGVSGGLLGVDLNLTSGCLTFYSLEPHTQPLHTFYAVFSRPLFPVFWLLEGRTLSLCHQPEAELPPRPQEEAIAPS", "length": 592 }, "evidence": [ { "id": "E1BKW8", "url": "https://omabrowser.org/oma/group/E1BKW8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RW04-1", "protein_name": "E3 ubiquitin-protein ligase TRIM65", "gene_name": "TRIM65", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAQRLEDRLTCAICLGLYQVPVTLLCGHNFCRGCIQDWWGRHEKACPECREPFPAGAEPRRNVALSGVVEELRARPAPGPGPGPDPGPGPDSDSGARCPRHGRPLELFCRTEGLCVCSACTVRECRLHERVLLDAERREREAQLRATLEVTQKQATKAESQLRELQQRSIQVQSSACTLASMVSGKFSRLLQALEMQRAMALKDIEAAKTQALEQARDEEQRLQGHLEALTHCDHRIHDLLEQSDDCTFLQESQLLAPPGPLGPLTLPQWNEDQFGDLKESLSQLCGLLLEAGSPPVVPAEAAAFDSMEAPGPLAPVLSPLCPLRRKLWQNYRNLTFDPISANRHLYLSQQDQQVKHCRKPQGPDGPDSFELWQVQCAQSFQAGRHYWEVRASSHSVTLGVAYPELKRRKLGPHTDNIGRGPTSWGLCIQEDRTQAWHNGVAQRLPGVSGRLLGMDLDLASGCLSFYSLEPKTQLLHTFHAIFTRPLYPIFWLLEGRTLTLCHRPEAKPPPGLQVEAAGLS", "length": 522 }, "evidence": [ { "id": "E1BKW8", "url": "https://omabrowser.org/oma/group/E1BKW8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6PJ69-1", "protein_name": "E3 ubiquitin-protein ligase TRIM65", "gene_name": "TRIM65", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKACPECREPFPDGAELRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCTVRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCRQSRGPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHSVTLGVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTFHALFNQPLTPVFWLLEGRTLTLCHQPGAVFPLGPQEEVLS", "length": 517 }, "evidence": [ { "id": "E1BKW8", "url": "https://omabrowser.org/oma/group/E1BKW8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BFW4-1", "protein_name": "E3 ubiquitin-protein ligase TRIM65", "gene_name": "Trim65", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAQLLEEDVVTCSICLGRYRDPVTLPCGHSFCGNCIQDSWRSCEKSCPECRQPFPEGAKLSRNVKMSTLLQALPVLPAPPAVTPRRDSATSHSARCLRHGRPLEFFCRTEGLCVCSACTVHDCSHHERALLDVERRVREDQLRARVLVTQQQVAQAETQLQELQEQRSRIESSACTLASVVSRRFSSLLQALEKQQASTLSDIEVAKKQALGQVLNEKQRLTDHLRALSQYDQSVQDLLAQADDCIFFQELQQLPEPTESLGPLTSPQWNEEQQLSNVNQLLSPLCELLLEEKSLPKVAAKAADAGPLETLGPLAPVPSAVCPLRKKLWQNYRNLTFDPETANQYLHLSHKDQRVTHHFQAQGPAKSGSFELWQVQCTQSFQTGQHYWEVRVSDHSVTLGVTYPKLSRQKLGTHTDNIGRGPCSWGLCIQEDSMQAWHNGKSQRLRGLPGQLLGVDLNLTSGCLTFYSLEPRTQPLHTFYAVFSQPLFPVFWLLEGRTLTLCHQPEATLPARPQEEATAPS", "length": 522 }, "evidence": [ { "id": "E1BKW8", "url": "https://omabrowser.org/oma/group/E1BKW8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WBJ0-1", "protein_name": "E3 ubiquitin-protein ligase TRIM65", "gene_name": "trim65", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDHMQCTICLDQFKFPVTIPCGHTFCKTCISKFWDGREKDFQCPVCKECYETRPQLNRNVSMSVLTEVACTVSPVKSDVCRGAAFQTEPEQICERHQKPLVIYCRNDGMCVCYECSLNECKGHDKILVETEQRNREAGLKKKSAEIKKHQEATEQNRLELMENLEKEKVSLQQTSQWVNSKFSQLIKVLAEKQEVTQLFLEQQQELTVLQAEESLSVLEERTTRLSALQEEIDSLCLLPPCQLIKDSRFMEVPRFAEVPVDVHAGVQEKLAPVTDVLSRVSKLVCEDLERAVQLSTGHQKDNSPQDKRPVLAVVPSPATPSYPAEREGLNAYHCALTFDPRTANAHLRLSQSNRRAEHLVSGPRPVPADESRFDHTWQVLCFQGFTSGQHYWELEVSKPWAYIGVTYPNIPRKQKGKRCMVGMNDLSWSLQLDERQMSAWHAGCKETVAGQLDNTHPLRIGLLLDYEAGTLTYYGEGQVRLHAFHCVFNQALFPACWIGEGVTVTLCEPRP", "length": 512 }, "evidence": [ { "id": "E1BKW8", "url": "https://omabrowser.org/oma/group/E1BKW8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" }, { "name": "regulation of protein-containing complex assembly", "id": "GO:0043254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043254", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" }, { "name": "positive regulation of interferon-beta production", "id": "GO:0032728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032728", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" }, { "name": "negative regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900226", "evidence": [ { "database": "UniProtKB", "id": "E1BKW8", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKW8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 548, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKW8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKW8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 307, "end_pos": 500, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKW8" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 51, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFX4-1", "uniprot_ac": "E1BFX4", "uniprot_id": "E1BFX4_BOVIN", "mass": { "chemical_mass": 57845.0, "monoisotopic_mass": 57845.0 }, "refseq": {}, "gene_names": [ { "name": "SGSH", "type": "recommended", "evidence": [ { "id": "E1BFX4", "database": "UniProtKB", "url": 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"id": "E1BFX4", "url": "https://www.orthodb.org/?gene=E1BFX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43108:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43108:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2024096", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2024096", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LQX3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFX4", "url": "https://www.uniprot.org/uniprotkb/E1BFX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFX4-1", "url": "https://www.uniprot.org/uniprotkb/E1BFX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R5B9", "url": "https://www.uniprot.org/uniprotkb/F6R5B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R5B9-1", "url": "https://www.uniprot.org/uniprotkb/F6R5B9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSSGQGCWVLLISVGLCCVHRARPRNVLLILADDGGFESGAYNNSAISTPHLDALARRSLVFRNAFTSVSSCSPSRASLLTGLPQHLCLQHQNGMYGLHQDVHHFNSFDRVQSLPLLLGRAGIHTGIIGKKHVGPEMVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTRGDRPFFLYVAFHDPHRCGHSQPQYGAFCEKFGNGESGMGRIPDWTPQTYNPKDVQVPYFVPDTPAARADLAAQYTTIGRMDQGIGLVLQELRGAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPMLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGTKTVQLTGRSLLPVLEAEPLWTTVFGSQSYHEVTMSYPMRSVHHQNFHLVHNLHFKMPFPIDQDFYISPTFQDLLNRTTAGQPTGWYKDLHQYYYRERWELYDRNQDPHETHNLAADPRYTQVLELLQTQLVKWQWETHDPWVCAPDGVLEEKLAPQCRPLHNEL", "length": 510, "header": "tr|E1BFX4-1|E1BFX4_BOVIN Isoform 1 of N-sulfoglucosamine sulfohydrolase OS=Bos taurus OX=9913 GN=SGSH PE=3 SV=2 CANONICAL=E1BFX4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQX3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFX4/entry#A0A3Q1LQX3-1", "sequence": { "sequence": "MRSSGQGCWVLLISVGLCCVHRARPRNVLLILADDGGFESGAYNNSAISTPHLDALARRSLVFRNAFTSVSSCSPSRASLLTGLPQSVVFPGKYKSQSPMGRTCGPVRRGVKDGENLSEDAKSGACEGPASLLAASEWNVRPAPGCPPLQLLRPGAEPATAAGPSWHSHRPFFLYVAFHDPHRCGHSQPQYGAFCEKFGNGESGMGRIPDWTPQTYNPKDVQVPYFVPDTPAARADLAAQYTTIGRMDQGIGLVLQELRGAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPMLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGTKTVQLTGRSLLPVLEAEPLWTTVFGSQSYHEVTMSYPMRSVHHQNFHLVHNLHFKMPFPIDQDFYISPTFQDLLNRTTAGQPTGWYKDLHQYYYRERWELYDRNQDPHETHNLAADPRYTQVLELLQTQLVKWQWETHDPWVCAPDGVLEEKLAPQCRPLHNEL", "length": 503, "header": "tr|A0A3Q1LQX3-1|E1BFX4_BOVIN Computationally mapped isoform of N-sulfoglucosamine sulfohydrolase OS=Bos taurus OX=9913 GN=SGSH PE=3 SV=2 CANONICAL=E1BFX4-1" }, "locus": { "chromosome": "19", "start_pos": 52430565, "end_pos": 52424231, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084291.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084291.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062616.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062616.2" } ] } }, { "isoform_ac": "E1BFX4-1", "url": "https://www.uniprot.org/uniprotkb/E1BFX4/entry#E1BFX4-1", "sequence": { "sequence": "MRSSGQGCWVLLISVGLCCVHRARPRNVLLILADDGGFESGAYNNSAISTPHLDALARRSLVFRNAFTSVSSCSPSRASLLTGLPQHLCLQHQNGMYGLHQDVHHFNSFDRVQSLPLLLGRAGIHTGIIGKKHVGPEMVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTRGDRPFFLYVAFHDPHRCGHSQPQYGAFCEKFGNGESGMGRIPDWTPQTYNPKDVQVPYFVPDTPAARADLAAQYTTIGRMDQGIGLVLQELRGAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPMLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGTKTVQLTGRSLLPVLEAEPLWTTVFGSQSYHEVTMSYPMRSVHHQNFHLVHNLHFKMPFPIDQDFYISPTFQDLLNRTTAGQPTGWYKDLHQYYYRERWELYDRNQDPHETHNLAADPRYTQVLELLQTQLVKWQWETHDPWVCAPDGVLEEKLAPQCRPLHNEL", "length": 510, "header": "tr|E1BFX4-1|E1BFX4_BOVIN Isoform 1 of N-sulfoglucosamine sulfohydrolase OS=Bos taurus OX=9913 GN=SGSH PE=3 SV=2 CANONICAL=E1BFX4-1" }, "locus": { "chromosome": "19", "start_pos": 52430565, "end_pos": 52424231, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020308.6", "url": "https://www.ensembl.org/id/ENSBTAT00000020308.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020308.4", "url": "https://www.ensembl.org/id/ENSBTAP00000020308.4" } ] } }, { "isoform_ac": "F6R5B9-1", "url": "https://www.uniprot.org/uniprotkb/E1BFX4/entry#F6R5B9-1", "sequence": { "sequence": "MPSPLSAAAHPAAPASSLACPSIRMECTACTRMSTTSTPSTGCRACHCCWAELAFTQVPYFVPDTPAARADLAAQYTTIGRMDQGIGLVLQELRGAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPMLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGTKTVQLTGRSLLPVLEAEPLWTTVFGSQSYHEVTMSYPMRSVHHQNFHLVHNLHFKMPFPIDQDFYISPTFQDLLNRTTAGQPTGWYKDLHQYYYRERWELYDRNQDPHETHNLAADPRYTQVLELLQTQLVKWQWETHDPWVCAPDGVLEEKLAPQCRPLHNEL", "length": 338, "header": "tr|F6R5B9-1|E1BFX4_BOVIN Computationally mapped isoform of N-sulfoglucosamine sulfohydrolase OS=Bos taurus OX=9913 GN=SGSH PE=3 SV=1 CANONICAL=E1BFX4-1" }, "locus": { "chromosome": "19", "start_pos": 52430565, "end_pos": 52425537, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056223.3", "url": "https://www.ensembl.org/id/ENSBTAT00000056223.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049692.2", "url": "https://www.ensembl.org/id/ENSBTAP00000049692.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-2024096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2024096", "resource": "Reactome", "description": "HS-GAG degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1BFX4", "url": "https://www.uniprot.org/uniprotkb/E1BFX4" } ], "pmid": "" }, { "name": "N-sulfoglucosamine sulfohydrolase activity", "id": "GO:0016250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016250", "evidence": [ { "database": "UniProtKB", "id": "E1BFX4", "url": "https://www.uniprot.org/uniprotkb/E1BFX4" } ], "pmid": "" }, { "name": "sulfuric ester hydrolase activity", "id": "GO:0008484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008484", "evidence": [ { "database": "UniProtKB", "id": "E1BFX4", "url": "https://www.uniprot.org/uniprotkb/E1BFX4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "E1BFX4", "url": "https://www.uniprot.org/uniprotkb/E1BFX4" } ], "pmid": "" }, { "name": "lysosomal lumen", "id": "GO:0043202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043202", "evidence": [ { "database": "UniProtKB", "id": "E1BFX4", "url": "https://www.uniprot.org/uniprotkb/E1BFX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycosaminoglycan catabolic process", "id": "GO:0006027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006027", "evidence": [ { "database": "UniProtKB", "id": "E1BFX4", "url": "https://www.uniprot.org/uniprotkb/E1BFX4" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan catabolic process", "id": "GO:0030200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030200", "evidence": [ { "database": "UniProtKB", "id": "E1BFX4", "url": "https://www.uniprot.org/uniprotkb/E1BFX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFX4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 510, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFX4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFX4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFX4" }, { "id": "PF16347", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16347" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-sulphoglucosamine sulphohydrolase C-terminal", "eco_id": "ECO_0000259", "start_pos": 427, "end_pos": 479, "start_aa": "Gln", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BFX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFX4" }, { "id": "PF00884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 335, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKT2-1", "uniprot_ac": "E1BKT2", "uniprot_id": "E1BKT2_BOVIN", "mass": { "chemical_mass": 60639.0, "monoisotopic_mass": 60639.0 }, "refseq": { "ac": "XP_002694823", "name": "TOX high mobility group box family member 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694823" }, "gene_names": [ { "name": "TOX3", "type": "recommended", "evidence": [ { "id": "E1BKT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ] }, { "name": "TOX3", "type": "synonym", "evidence": [ { "id": "XP_002694823", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694823" } ] } ], "protein_names": [ { "name": "TOX high mobility group box family member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002694823", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694823" } ] }, { "name": "TOX high mobility group box family member 3", "type": "synonym", "evidence": [ { "id": "E1BKT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TOX3", "url": "https://www.uniprot.org/uniprotkb/E1BKT2", "locus": { "chromosome": "18", "start_pos": 20893616, "end_pos": 21014959, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000418", "url": "https://www.ensembl.org/id/ENSBTAG00000000418" } ] } } ], "crossref": [ { "id": "E1BKT2", "url": "https://alphafold.ebi.ac.uk/entry/E1BKT2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000418", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000418", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21995", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21995", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539135", "url": "https://www.ncbi.nlm.nih.gov/gene/539135", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539135", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539135", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYSKFGN", "url": "https://omabrowser.org/oma/group/AYSKFGN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKT2", "url": "https://www.orthodb.org/?gene=E1BKT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45781", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45781", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45781:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45781:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002694823", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694823", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LR78", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LR78-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXJ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKT2-1", "url": "https://www.uniprot.org/uniprotkb/E1BKT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVRFYPAAAGDPAGLDFAQCLGYYGYSKFGNNNNYMNMAEANNAFFAASEQTFHTPSLGDEEFEIPPITPPPESDPALGMPDVLLPFQGLSDPLPSQGSEFTPQFPPQSLDLPSITISRNLVEQDGVLHSSGLHMDQSHTQVSQYRQDPSVIMRSIVHMTDAARSGIMPPAQLTTINQSQLSAQLGLNLGGASVPHTSPSPPASKSATPSPSSSINEEDADETNRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNPPLSQHGTVSASPQTLQPSLPRSIAPKPLTMRLPVNPMVTSVTIAANMPSNLGAPLISSMVGSASSAQVSPSVQTQQQQQQQQMQQLQQQQLQQQQLQQQQLQQQLQQQHFQHHVQLQQQQLQQHINQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVTSQITSPIPALGSPQPASQQHPSQIQSQTQTQVLSQVSIF", "length": 556, "header": "tr|E1BKT2-1|E1BKT2_BOVIN Isoform 1 of TOX high mobility group box family member 3 OS=Bos taurus OX=9913 GN=TOX3 PE=4 SV=1 CANONICAL=E1BKT2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LR78-1", "url": "https://www.uniprot.org/uniprotkb/E1BKT2/entry#A0A3Q1LR78-1", "sequence": { "sequence": "MNLRAPCFGNNNNYMNMAEANNAFFAASEQTFHTPSLGDEEFEIPPITPPPESDPALGMPDVLLPFQGLSDPLPSQGSEFTPQFPPQSLDLPSITISRNLVEQDGVLHSSGLHMDQSHTQVSQYRQDPSVIMRSIVHMTDAARSGIMPPAQLTTINQSQLSAQLGLNLGGASVPHTSPSPPASKSATPSPSSSINEEDADETNRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNPPLSQHGTVSASPQTLQPSLPRSIAPKPLTMRLPVNPMVTSVTIAANMPSNLGAPLISSMVGSASSAQVSPSVQTQQQQQQQQMQQLQQQQLQQQQLQQQQLQQQLQQQHFQHHVQLQQQQLQQHINQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVTSQITSPIPALGSPQPASQQHPSQIQSQTQTQVLSQVSIF", "length": 534, "header": "tr|A0A3Q1LR78-1|E1BKT2_BOVIN Computationally mapped isoform of TOX high mobility group box family member 3 OS=Bos taurus OX=9913 GN=TOX3 PE=4 SV=2 CANONICAL=E1BKT2-1" }, "locus": { "chromosome": "18", "start_pos": 20928393, "end_pos": 20894620, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082075.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082075.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059495.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059495.2" } ] } }, { "isoform_ac": "A0AAA9SXJ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BKT2/entry#A0AAA9SXJ6-1", "sequence": { "sequence": "MKFGNNNNYMNMAEANNAFFAASEQTFHTPSLGDEEFEIPPITPPPESDPALGMPDVLLPFQGLSDPLPSQGSEFTPQFPPQSLDLPSITISRNLVEQDGVLHSSGLHMDQSHTQVSQYRQDPSVIMRSIVHMTDAARSGIMPPAQLTTINQSQLSAQLGLNLGGASVPHTSPSPPASKSATPSPSSSINEEDADETNRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNPPLSQHGTVSASPQTLQPSLPRSIAPKPLTMRLPVNPMVTSVTIAANMPSNLGAPLISSMVGSASSAQVSPSVQTQQQQQQQQMQQLQQQQLQQQQLQQQQLQQQLQQQHFQHHVQLQQQQLQQHINQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVTSQITSPIPALGSPQPASQQHPSQIQSQTQTQVLSQVSIF", "length": 529, "header": "tr|A0AAA9SXJ6-1|E1BKT2_BOVIN Computationally mapped isoform of TOX high mobility group box family member 3 OS=Bos taurus OX=9913 GN=TOX3 PE=4 SV=1 CANONICAL=E1BKT2-1" }, "locus": { "chromosome": "18", "start_pos": 20984765, "end_pos": 20894620, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096952.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096952.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088941.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088941.1" } ] } }, { "isoform_ac": "E1BKT2-1", "url": "https://www.uniprot.org/uniprotkb/E1BKT2/entry#E1BKT2-1", "sequence": { "sequence": "MDVRFYPAAAGDPAGLDFAQCLGYYGYSKFGNNNNYMNMAEANNAFFAASEQTFHTPSLGDEEFEIPPITPPPESDPALGMPDVLLPFQGLSDPLPSQGSEFTPQFPPQSLDLPSITISRNLVEQDGVLHSSGLHMDQSHTQVSQYRQDPSVIMRSIVHMTDAARSGIMPPAQLTTINQSQLSAQLGLNLGGASVPHTSPSPPASKSATPSPSSSINEEDADETNRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNPPLSQHGTVSASPQTLQPSLPRSIAPKPLTMRLPVNPMVTSVTIAANMPSNLGAPLISSMVGSASSAQVSPSVQTQQQQQQQQMQQLQQQQLQQQQLQQQQLQQQLQQQHFQHHVQLQQQQLQQHINQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVTSQITSPIPALGSPQPASQQHPSQIQSQTQTQVLSQVSIF", "length": 556, "header": "tr|E1BKT2-1|E1BKT2_BOVIN Isoform 1 of TOX high mobility group box family member 3 OS=Bos taurus OX=9913 GN=TOX3 PE=4 SV=1 CANONICAL=E1BKT2-1" }, "locus": { "chromosome": "18", "start_pos": 21014760, "end_pos": 20894620, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000539.5", "url": "https://www.ensembl.org/id/ENSBTAT00000000539.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000539.3", "url": "https://www.ensembl.org/id/ENSBTAP00000000539.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 209, "start_aa": "Thr", "end_pos": 209, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr209", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 70, "start_aa": "Thr", "end_pos": 70, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr70", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539135", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539135", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PEI4-1", "protein_name": "TOX high mobility group box family member 3", "gene_name": "TOX3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDVRFYPSAAGGSLPGDPSNLDFAQCLGYYNYNKFGNNNNYMNMAEANNAFLAANEQTFHTPSLGDEEFEIPPITPPPESDPALGMADILLPFQGLGDQLPAQGNEFTPQFPPQSLDLPSITISRNLMEQDGVIHSNGLHMDQSHTQVSQYRQDHSLIMRSIVHMTDAAHSGIMTPSQLTTINQSQLSAQLGLNLGGTNLPHTSPSPPASKSATPSPSSSINEEDADESNRATGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLSSSLILNTSLSQHATVSASPQTLQQSLPRAIAPKPLTMRLPMNQIVASVTIASNMPTNIAAPLISSMGTNMVATPSSSQVSPSMQSQQHQIQQLQQQQMQQMQQQQLHQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQMQQQLQHIQLQQMQQQQMQHMQHQSQPSPQQHSPVASQITSPIPAIGSPQPAPQQHQSQIQSQTQTQVLSQVSIF", "length": 580 }, "evidence": [ { "id": "E1BKT2", "url": "https://omabrowser.org/oma/group/E1BKT2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A480R5F1-1", "protein_name": "TOX high mobility group box family member 3", "gene_name": "TOX3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRFYPAAAGDPAGLDFAQCLGYYGYSKFANNNNYMNMAEANNAFFAASEQTFHTPSLGDEEFEIPPITPPPESDPALGMPDVLLPFQGLSDALPSQGSEFTPQFPPQSLDLPSITISRNLVEQDGVLHSSGLHMDQSHTQVSQYRQDPSLVMRSIVHMTDAARSGIMPPAQLTTINQSQLSAQLGLNLGGASVPHTSPSPPASKSATPSPSSSINEEDADESNRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNPPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAPLISSMVGSASSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQHLQQQINQQQLQQQLQQHLQLQQLQHLQHQSQPSPRQHSPVTSQITSPVPTIGSPQPASQQHQSQIQSQTQTQVLSQVSIF", "length": 571 }, "evidence": [ { "id": "E1BKT2", "url": "https://omabrowser.org/oma/group/E1BKT2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B7SBD2-1", "protein_name": "TOX high mobility group box family member 3", "gene_name": "Tox3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVRFYPAAAGDPAGLDFAQCLGYYGYSKLGNNNYMNMAEANNAFFAASEQTFHTPSLGDEEFEIPPITPPPESDPTLGMPDVLLPFQTLSDPLPSQGNEFTPQFPPQSLDLPSITISRNLVEQDGVLHSNGLHMDQSHTQVSQYRQDPSLVMRSIVHMTDAARSGIMPPAQLTTINQSQLSAQLGLNLGGASVPHTSPSPPASKSATPSPSSSINEEDADETNRAVGEKRTAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNTSLSQHGTVPASPQTLPQSLPRSIAPKPLTMRLPMSQIVTSVTIAANMPSNIGAPLISSMGTTMVGSVSSTQVSPSVQTQQHQLQLQQQQQQQQQQMQQMQHQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQQHLQQQISQQQLQQQLQQHLQLQQQLQHMQHQSQPSPRQHSPVTSQITSPIPAIGSPQPASQQHQPQIQSQTQTQVLPQVSIF", "length": 577 }, "evidence": [ { "id": "E1BKT2", "url": "https://omabrowser.org/oma/group/E1BKT2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15405-1", "protein_name": "TOX high mobility group box family member 3", "gene_name": "TOX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVRFYPAAAGDPASLDFAQCLGYYGYSKFGNNNNYMNMAEANNAFFAASEQTFHTPSLGDEEFEIPPITPPPESDPALGMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLPSITISRNLVEQDGVLHSSGLHMDQSHTQVSQYRQDPSLIMRSIVHMTDAARSGVMPPAQLTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVLSQVSIF", "length": 576 }, "evidence": [ { "id": "E1BKT2", "url": "https://omabrowser.org/oma/group/E1BKT2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80W03-1", "protein_name": "TOX high mobility group box family member 3", "gene_name": "Tox3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDVRFYPAAAGDPAGLDFAQCLGYYGYSKLGNNNYMNMAEANNAFFAASEQTFHTPSLGDEEFEIPPITPPPESDPTLGMPDALLPFQTLSDPLPSQGTEFTPQFPPQSLDLPSITISRNLVEQDGVLHSNGLHMDQSHTQVSQYRQDPSLVMRSIVHMTDGARSGIMPPAQLTTINQSQLSAQLGLNLGGANVSHTSPSPPASKSATPSPSSSINEEDADDANRAIGEKRTAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNTSLSQHGTVPASPQTLPQSLPRSIAPKPLTMRLPMSQIVTSVTIAANMPSNIGAPLISSMGTTMVGSATSTQVSPSVQTQQHQMQLQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQQHLQQQLSQQQLQQQLQQHLQLQQLQHMQHQSQPSPRQHSPVTSQITSPIPAIGSPQPASQQHQPQIQSQTQTQVLPQVSIF", "length": 575 }, "evidence": [ { "id": "E1BKT2", "url": "https://omabrowser.org/oma/group/E1BKT2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "pmid": "" }, { "name": "phosphoprotein binding", "id": "GO:0051219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051219", "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "E1BKT2", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKT2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 556, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKT2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKT2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT2" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 255, "end_pos": 323, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 70, 209 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 351, "end_pos": 353 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEL3-1", "uniprot_ac": "E1BEL3", "uniprot_id": "E1BEL3_BOVIN", "mass": { "chemical_mass": 85735.0, "monoisotopic_mass": 85735.0 }, "refseq": { "ac": "NP_788808", "name": "myb-related protein A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788808" }, "gene_names": [ { "name": "MYBL1", "type": "recommended", "evidence": [ { "id": "E1BEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" } ] }, { "name": "MYBL1", "type": "synonym", "evidence": [ { "id": "NP_788808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788808" } ] } ], "protein_names": [ { "name": "MYB proto-onco like 1", "type": "synonym", "evidence": [ { "id": "E1BEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL3/entry#names_and_taxonomy" } ] }, { "name": "myb-related protein A", "type": "synonym", "evidence": [ { "id": "NP_788808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788808" } ] } ], "function": [ { "annotation": "Evaluation of MYBL1 as the master regulator for pachytene spermatocyte genes dysregulated in interspecific hybrid dzo.", "evidence": [ { "database": "RefSeq", "id": "NP_788808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788808" }, { "database": "PubMed", "id": "37059660", "url": "https://glygen.org/publication/PubMed/37059660" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEL3", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MYBL1", "url": "https://www.uniprot.org/uniprotkb/E1BEL3", "locus": { "chromosome": "14", "start_pos": 30827097, "end_pos": 30862266, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011981", "url": "https://www.ensembl.org/id/ENSBTAG00000011981" } ] } } ], "crossref": [ { "id": "E1BEL3", "url": "https://alphafold.ebi.ac.uk/entry/E1BEL3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011981", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011981", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "338034", "url": "https://www.ncbi.nlm.nih.gov/gene/338034", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:338034", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:338034", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QMGGFPF", "url": "https://omabrowser.org/oma/group/QMGGFPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LRR5", "url": "https://www.orthodb.org/?gene=A0A3Q1LRR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BEL3", "url": "https://www.orthodb.org/?gene=E1BEL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45614:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45614:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46621", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46621", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46621:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46621:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07988", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07988", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09316", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09316", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_788808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788808", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRR5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCY8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEL3", "url": "https://www.uniprot.org/uniprotkb/E1BEL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEL3-1", "url": "https://www.uniprot.org/uniprotkb/E1BEL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCATMDHLQTQNQFYIPVQIPGYQYVSPEGNCVEHVQASSAFIQQPFVDEDPDKEKKIKELELLLMSAENEVRRKRVPSQPGSFSSWPGSFLMDDSMSNTLNSLEEHASEFYSMDENQTVSAQQNSPTKFLAVEANAVLSSLQTIPEFAETLELIESDPVAWSDVTSFDLSDAAASPVKSTPVKLMRIQHNEGAMECQFNVSLVLEGKRNGCNGADGEAVPLTSPSVPKFSTPPTILRKKRRMRVGQSPGSELGDSSFNDGGHTALKHTPMKTLPFSPSQFFNTCPGNEQINIENPSFTSTPICGQKVLITTPLHKETTPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETGTDIFLKEEDEPAYKSCKQEHTASVKKVRKSLILDNWEKEEPGTQLLNEDLSDLQSENIFTTSLLMIPLLEIHDNRCNLTPEKQDINSTNKTYTLNKKKPNPNTSKVVTLEKNLQSTCEWETVVYGKTEDQLIMTEQARRYLSTYTATGSTSRALIL", "length": 752, "header": "tr|E1BEL3-1|E1BEL3_BOVIN Isoform 1 of MYB proto-onco like 1 OS=Bos taurus OX=9913 GN=MYBL1 PE=4 SV=3 CANONICAL=E1BEL3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LRR5-1", "url": "https://www.uniprot.org/uniprotkb/E1BEL3/entry#A0A3Q1LRR5-1", "sequence": { "sequence": "MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCATMDHLQTQNQFYIPVQIPGYQYVSPEGNCVEHVQASSAFIQQPFVDEDPDKEKKIKELELLLMSAENEVRRKRVPSQPGSFSSWPGSFLMDDSMSNTLNSLEEHASEFYSMDENQTVSAQQNSPTKFLAVEANAVLSSLQTIPEFAETLELIESDPVAWSDVTSFDLSDAAASPVKSTPVKLMRIQHNEGAMECQFNVSLVLEGKRNGCNGADGEAVPLTSPSVPKFSTPPTILRKKRRMRVGQSPGSELGDSSFNDGGHTALKHTPMKTLPFSPSQFFNTCPGNEQINIENPSFTSTPICGQKVLITTPLHKETTPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETGTDIFLKEEDEPAYKSCKQEHTASVKKVRKSLILDNWEKEEPGTQLLNEDLSDLQSTCEWETVVYGKTEDQLIMTEQARRYLSTYTATGSTSRALIL", "length": 692, "header": "tr|A0A3Q1LRR5-1|E1BEL3_BOVIN Computationally mapped isoform of MYB proto-onco like 1 OS=Bos taurus OX=9913 GN=MYBL1 PE=4 SV=1 CANONICAL=E1BEL3-1" }, "locus": { "chromosome": "14", "start_pos": 30862209, "end_pos": 30828101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069403.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069403.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062971.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062971.1" } ] } }, { "isoform_ac": "A0AAA9SCY8-1", "url": "https://www.uniprot.org/uniprotkb/E1BEL3/entry#A0AAA9SCY8-1", "sequence": { "sequence": "MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGKKRRMRVGQSPGSELGDSSFNDGGHTALKHTPMKTLPFSPSQFFNTCPGNEQINIENPSFTSTPICGQKVLITTPLHKETTPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETGTDIFLKEEDEPAYKSCKQEHTASVKKVRKSLILDNWEKEEPGTQLLNEDLSDLQSENIFTTSLLMIPLLEIHDNRCNLTPEKQDINSTNKTYTLNKKKPNPNTSKVVTLEKNLQSTCEWETVVYGKTEDQLIMTEQARRYLSTYTATGSTSRALIL", "length": 410, "header": "tr|A0AAA9SCY8-1|E1BEL3_BOVIN Computationally mapped isoform of MYB proto-onco like 1 OS=Bos taurus OX=9913 GN=MYBL1 PE=4 SV=1 CANONICAL=E1BEL3-1" }, "locus": { "chromosome": "14", "start_pos": 30862209, "end_pos": 30828101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135222.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135222.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083989.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083989.1" } ] } }, { "isoform_ac": "E1BEL3-1", "url": "https://www.uniprot.org/uniprotkb/E1BEL3/entry#E1BEL3-1", "sequence": { "sequence": "MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCATMDHLQTQNQFYIPVQIPGYQYVSPEGNCVEHVQASSAFIQQPFVDEDPDKEKKIKELELLLMSAENEVRRKRVPSQPGSFSSWPGSFLMDDSMSNTLNSLEEHASEFYSMDENQTVSAQQNSPTKFLAVEANAVLSSLQTIPEFAETLELIESDPVAWSDVTSFDLSDAAASPVKSTPVKLMRIQHNEGAMECQFNVSLVLEGKRNGCNGADGEAVPLTSPSVPKFSTPPTILRKKRRMRVGQSPGSELGDSSFNDGGHTALKHTPMKTLPFSPSQFFNTCPGNEQINIENPSFTSTPICGQKVLITTPLHKETTPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETGTDIFLKEEDEPAYKSCKQEHTASVKKVRKSLILDNWEKEEPGTQLLNEDLSDLQSENIFTTSLLMIPLLEIHDNRCNLTPEKQDINSTNKTYTLNKKKPNPNTSKVVTLEKNLQSTCEWETVVYGKTEDQLIMTEQARRYLSTYTATGSTSRALIL", "length": 752, "header": "tr|E1BEL3-1|E1BEL3_BOVIN Isoform 1 of MYB proto-onco like 1 OS=Bos taurus OX=9913 GN=MYBL1 PE=4 SV=3 CANONICAL=E1BEL3-1" }, "locus": { "chromosome": "14", "start_pos": 30862209, "end_pos": 30828101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015897.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015897.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015897.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015897.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Evaluation of MYBL1 as the master regulator for pachytene spermatocyte genes dysregulated in interspecific hybrid dzo.", "journal": "Journal of dairy science", "date": "2023-06", "authors": "Zhang Gong-Wei, Wang Ling, Wu Jingjing, Ye Yiru, Zhao Jianjun, Du Yanan, Tu Yun, Luo Zonggang, Fu Shubing, Zuo Fuyuan", "evidence": [ { "database": "RefSeq", "id": "NP_788808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788808" } ], "reference": [ { "type": "PubMed", "id": "37059660", "url": "https://glygen.org/publication/PubMed/37059660" } ] } ], "pathway": [ { "id": "bta:338034", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:338034", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ARW4-1", "protein_name": "MYB proto-oncogene like 1", "gene_name": "Mybl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCATMDHLQTQNQFYIPVQIPGYQYVSPDGNCVEHVQTSAFIQQPFVDEDPDKEKKIKELELLLMSAENEVRRKRLPPQPGSFSSWSGSFLMDDSMSNTLNNLEEHTTEFYSMDENQTVSAQQNSPTKFLAVEANAVLSSLQTIPEFAETLELIESDPVAWSDVTSFDLSDAAASPVKSTPVKLMRIQHNEGAMECQFNVSLVLEGKKNSCNGGDSEAIPLASPNVVKFSTPPTILRKKKRLRVGQSAGSELGEGSLSEGNNAALKHTPVKTLPFSPSQFFNTCPGSEQLNIENPSFTSTPICGQKVLITTPLQKEATPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETGTDIFLKEEDEPAYKSCKQEHSASVKKVRKSLALESWDKEEPGTQLLTEDISDMQSENILTTSLLMIPLLEIHDNRCNLTPEKQDINSANKTYTLTKKRPNPNTCKAVKLEKSLQSNCEWETVVYGKTEDQLIMTEQARRYLSTYTAPSSTSRALIL", "length": 751 }, "evidence": [ { "id": "E1BEL3", "url": "https://omabrowser.org/oma/group/E1BEL3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2B9R3-1", "protein_name": "Myb-related protein A isoform X1", "gene_name": "mybl1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANMKSRSEDEDEDRHSTDPDSREPKNSKRTLCKIKWSRDEDEKLKKLVEQQGTDNWKLIANYFPTRTDGQCQHRWQKVLNPELVKGPWTKEEDQRVIELVHKYGPKRWSVIAKHLQGRIGKQCRERWHNHLNPEVKKSSWTQEEDRIIYEAHKRLGNRWAEISKLLPGRTDNSIKNHWNSTMRRKVEHEGYLQEGNKSYNSDPGQKKRPKSSPTVEYPHDQNQPILSGQSQPPRYPYRSQSAQCLENINVRISSFVSPFHDDPDKEKRIKELELLLMSAESEVRRQSGPRNPESYSSWSDSLPDDSVESVEDRGVEDGRSVSIPLPVSPSKFLAAEASAVLSTLETIPEFAETMELIDSVSRDPLAWSDVTSFDLSESGPSPKPTNPADVCTETLAFPINAPTVQTMTRPCAAVSQGKSGTLPNTCMNRFSSPPTSICRKKRREGGDQSPAEERSCSYIDNSGNSPKHTPVKGLPFSPSQFFNVSGGEPLSLDNPALTSTPVCGQKCLLNTPHQKETTPKHQKENAGFRTPKLHKNIVVHTPRTPTPFKNALAAQEKMHGPLRMVPQPLALLEEDIREVLKEETGADIFTQVQNQLQYRSYEQMEAPARKVRKSLVLDSWEKDCLNVQLFPQQQINNNGTTSQSDGLLTRSMLMMPLTEREENSCSPESLKDSLSVVCSVSPQGKRENMIQRSPLYQTPTPANNEWDAVVFGKTEDQLIMTEQARRYLNPNPTACISRALVL", "length": 743 }, "evidence": [ { "id": "E1BEL3", "url": "https://omabrowser.org/oma/group/E1BEL3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0XBS3-1", "protein_name": "MYB proto-onco like 1", "gene_name": "MYBL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPRSSAGGRESSQEREASFGRRCPSPPPARPELGGCGAGSSGGGWGAPLPWRPPLCCDPRMAKRPRSSEEDDDFQYADHDYEISQQRSLKKICNRVKWTRDEDEKLKKLVEQNGTDDWAFIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEEDRVIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGTKSSSERTGSSTLAQKPCVTMEHLHTQNQFYIPVQTHIPVYQYASPEDSCIEHASASANLVQQSFIDDDPDKEKKIKELELLLMSTENEIRRKRLSSQAGSLPGWSGSFVMEDCVPNTLNSLGEQTSEFYSMDETQGTSVQQNSPTKYLAVEANAVLSSLQTIPEFAETLELIESDPLAWSDVTSFDLSEAVASPVKPAPLKLMRIQHNERAAECQFNVSVMLDGKKHSSISGEEEAVFPTTPNLTKYSTPPAILRKKKRLRAGQSPVNELNDGLCNDAINVALKHTPVKTLPFSPSQFFNTCSGNEQFNLENPAFTSTPICGQKVLITTPLHKETTPTDQKENAGFRTPTIRRSLLGSTPRTPTPFKNALAAQEKKYGPLKLTSQPLAFLEEDIREVLKEETGTDIFLKEEDDSVYKSCKQEHNSSKKVRKSLVLDAWEKEELGAQLFTEDSGLDVQSENAYTTSLLMIPLLEIHDNRCNLPSENQDTNSSNKANAVIKKKLNACSSKNIKLEKSLQPNYEWEAVVYGKTEDQLIMTEQARRYLNAYTATSNTSRALIL", "length": 817 }, "evidence": [ { "id": "E1BEL3", "url": "https://omabrowser.org/oma/group/E1BEL3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P10243-1", "protein_name": "Myb-related protein A", "gene_name": "MYBL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCAAMDHMQTQNQFYIPVQIPGYQYVSPEGNCIEHVQPTSAFIQQPFIDEDPDKEKKIKELEMLLMSAENEVRRKRIPSQPGSFSSWSGSFLMDDNMSNTLNSLDEHTSEFYSMDENQPVSAQQNSPTKFLAVEANAVLSSLQTIPEFAETLELIESDPVAWSDVTSFDISDAAASPIKSTPVKLMRIQHNEGAMECQFNVSLVLEGKKNTCNGGNSEAVPLTSPNIAKFSTPPAILRKKRKMRVGHSPGSELRDGSLNDGGNMALKHTPLKTLPFSPSQFFNTCPGNEQLNIENPSFTSTPICGQKALITTPLHKETTPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETGTDLFLKEEDEPAYKSCKQENTASGKKVRKSLVLDNWEKEESGTQLLTEDISDMQSENRFTTSLLMIPLLEIHDNRCNLIPEKQDINSTNKTYTLTKKKPNPNTSKVVKLEKNLQSNCEWETVVYGKTEDQLIMTEQARRYLSTYTATSSTSRALIL", "length": 752 }, "evidence": [ { "id": "E1BEL3", "url": "https://omabrowser.org/oma/group/E1BEL3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51960-1", "protein_name": "Myb-related protein A", "gene_name": "Mybl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCATMDHLQTQNQFYIPVQIPGYQYVSPDGNCVEHVQTSAFIQQPFVDEDPDKEKKIKELELLLMSAENEVRRKRLPPQPGSFSSWSGSFLMDDSMSNTLNNLEEHTTEFYSMDENQTVSAQQNSPTKFLAVEANAVLSSLQTIPEFPRTLELIESDPVAWSDVTSFDLSDAAASPVKSTPVKLMRIQHNEGAMECQFNVSLVLEGKKNSRNGGDSEAIPLTSPNVVKFSTPPTISRKKKRIRVGQSAGSELGSASLSEVGNRRIKHTPVKTLPFSPSQFFNTCPGNEQLNIENPSFTSTPICGQKVLITTPLQKEATPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETGTDIFLKEEDEPAYKSCKQEHSASVKKVRKSLALESWDKEEPGTQLLTEDISDMQSENILTTSLLMIPLLEIHDNRCNLTPEKQDINSANKTYTLNKKRPNPNPCKAVKLEKSLQSNCEWETVVYGKTEDQLIMTEQARRYLSTYTATSSTSRALIL", "length": 751 }, "evidence": [ { "id": "E1BEL3", "url": "https://omabrowser.org/oma/group/E1BEL3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BEL3", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BEL3", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BEL3", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BEL3", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BEL3", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BEL3", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BEL3", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "E1BEL3", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BEL3", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 682, "end_pos": 684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 698, "end_pos": 700, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEL3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 752, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEL3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEL3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" }, { "id": "PS51294", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51294" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH myb-type", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 81, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL3" }, { "id": "PS50090", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50090" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb-like", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 81, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 673, "end_pos": 675 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 682, "end_pos": 684 }, { "start_pos": 685, "end_pos": 687 }, { "start_pos": 698, "end_pos": 700 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1BH05-1", "uniprot_ac": "E1BH05", "uniprot_id": "E1BH05_BOVIN", "mass": { "chemical_mass": 149431.0, "monoisotopic_mass": 149431.0 }, "refseq": { "ac": "XP_010818492", "name": "rho guanine nucleotide exchange factor 10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818492" }, "gene_names": [ { "name": "ARHGEF10", "type": "recommended", "evidence": [ { "id": "E1BH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH05" } ] }, { "name": "ARHGEF10", "type": "synonym", "evidence": [ { "id": "XP_010818492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818492" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 10", "type": "recommended", "evidence": [ { "id": "E1BH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH05/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010818492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818492" } ] } ], "function": [ { "annotation": "May play a role in developmental myelination of peripheral nerves.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LS11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS11#function" }, { "database": "UniProtKB", "id": "ARBA00058240", "url": "https://www.uniprot.org/uniprotkb/ARBA00058240#function" }, { "database": "UniProtKB", "id": "E1BH05", "url": "https://www.uniprot.org/uniprotkb/E1BH05#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BH05", "url": "https://www.uniprot.org/uniprotkb/E1BH05" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARHGEF10", "url": "https://www.uniprot.org/uniprotkb/E1BH05", "locus": { "chromosome": "27", "start_pos": 1408800, "end_pos": 1347276, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008585", "url": "https://www.ensembl.org/id/ENSBTAG00000008585" } ] } } ], "crossref": [ { "id": "ENSBTAG00000008585", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008585", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100138303", "url": "https://www.ncbi.nlm.nih.gov/gene/100138303", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100138303", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138303", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NSDSEPX", "url": "https://omabrowser.org/oma/group/NSDSEPX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LS11", "url": "https://www.orthodb.org/?gene=A0A3Q1LS11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BH05", "url": "https://www.orthodb.org/?gene=E1BH05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12877", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12877", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12877:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12877:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19056", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19056", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010818492", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818492", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LS11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LS11-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH05", "url": "https://www.uniprot.org/uniprotkb/E1BH05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH05-1", "url": "https://www.uniprot.org/uniprotkb/E1BH05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQPGPPAPAREENEVKYDTNNNEEEEEEGEQLDLDSGDEAPEADRQAPGSAEAGDAGADAPATAATAATAGPCASSGHHPGTSQPTCGLDRPGEGCEKGPGVEPLKPGVPSRVNPYSVIDITPLQEDQPPPPDPDAEGEGGGLHVPSGYLVPVPCGYAVPSSLPLLLPAYTSPVLPAPPADPAETQEAAEDSQLNSLSSEDPANSEDPDQKEDSALARWVADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGHSSLEYGWSSSEFESYEEQSDSESRSGVPRSFLRGDHRKQLSHDLTRLKEHYERKMRELMANTVGAVEIQQLKHKHELKMQKLVRAAREGTKDGLEKTKAAVKRGRSFIRTKSFISADHRSCLEEEQNVFIDVDCKHPEAILTPMPEGLSQQQVVRRYILGSIVDSEKNYVDALKRILEQYEKPLWEMEPKVLSERKLRTVFFRVKEVLQCHCLLQIALAGRVAEWDSVEMIGDVFVASFSKSMVLDAYSEYVNNFSTAVAILKKTCATKPAFLEFLKQCQESSPDRVTLHSLMTKPIQRFPQFILLLQDMLKNTPRGHPDRLPLQMALTELETLAEKLNERKRDADQRCEIKQIAKAINERYLNKLLSSGSRYLIRSDDVIETVYNDRGEIMKTKERRLFMLNDVLMCATVSTRAPSSRSASHDGGAVTSGQRYLLKWSVPLGQAEVVEYGGGEGVAEGGRCPTGPAPESLLAASTKPHRVYVGPGQLYQDLQNLLHDLSVIGHITQLVGNLKGNYQNLNPLVAQDWMSGLQRLILKKEEEIRAADCCRVQLQLPGKQDKSGRPTFFTAVFNTFTPAIKESWINSLQMAKLALEEENHLGWFCVEDDGNQIRKERHPLLLGHMPVTVAKQQEFKIECAVYNPEPYLNNENQSDSFSVAHGFLWIGSCTSQMGQIAIVSFHNSSPKVIECFNVESRVLCMVYVPAEDRPREPEGGGRVLGVPAVCLGTEEGSISIYKSSQGCKKVRLQHFFTPEKSTVMSLACTAQSLYAGLVNGAVAVYARADDGSWNSEPQTVIKLGVLPVRSLLLMEDTLWAASGGQVFIISVETLAVEGQLEAHQEEGMVVSHMAIAGVGIWVAFTSGSTLRLFHTETLKHLQDVNIATPVHHMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGLVSHHAHHGPVKFLVVAAAALKADKDRPRDSPPPGADPQDDEQRDVPSSEGPGLCMGRGGPDAVWLGTSPGSITQGSDVSSSSGSPTPSQGSGSLEPRPEESLAQDLLRLPCTSPSRGRRARRPRASSVLVACGGQGHRRVSRKARPQRPEELASSLMVWQIPLLHV", "length": 1366, "header": "tr|E1BH05-1|E1BH05_BOVIN Isoform 1 of Rho guanine nucleotide exchange factor 10 OS=Bos taurus OX=9913 GN=ARHGEF10 PE=4 SV=3 CANONICAL=E1BH05-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LS11-1", "url": "https://www.uniprot.org/uniprotkb/E1BH05/entry#A0A3Q1LS11-1", "sequence": { "sequence": "MDQPGPPAPAREENEVKYDTNNNEEEEEEGEQLDLDSGDEAPEADRQAPGSAEAGDAGADAPATAATAATAGPCASSGHHPGTSQPTCGLDRPGEGCEKGPGVEPLKPGVPSRVNPYSVIDITPLQEDQPPPPDPDAEGEGGGLHVPSGYLVPVPCGYAVPSSLPLLLPAYTSPVLPAPPADPAETQEAAEDSQLNSLSSEDPANSEDPDQKEDSALARWVADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGHSSLEYGWSSSEFESYEEQSDSESRSGVPRSFLRGDHRKQMQKLVRAAREGTKDGLEKTKAAVKRGRSFIRTKSFISADHRSCLEEEQNVFIDVDCKHPEAILTPMPEGLSQQQVVRRYILGSIVDSEKNYVDALKRILEQYEKPLWEMEPKVLSERKLRTVFFRVKEVLQCHCLLQIALAGRVAEWDSVEMIGDVFVASFSKSMVLDAYSEYVNNFSTAVAILKKTCATKPAFLEFLKQCQESSPDRVTLHSLMTKPIQRFPQFILLLQDMLKNTPRGHPDRLPLQMALTELETLAEKLNERKRDADQRCEIKQIAKAINERYLNKLLSSGSRYLIRSDDVIETVYNDRGEIMKTKERRLFMLNDVLMCATVSTRAPSSRSASHDGGAVTSGQRYLLKWSVPLGQAEVVEYGGGEGVAEGGRCPTGPAPESLLAASTKPHRVYVGPGQLYQDLQNLLHDLSVIGHITQLVGNLKGNYQNLNPLVAQDWMSGLQRLILKKEEEIRAADCCRVQLQLPGKQDKSGRPTFFTAVFNTFTPAIKESWINSLQMAKLALEEENHLGWFCVEDDGNQIRKERHPLLLGHMPVTVAKQQEFKIECAVYNPEPYLNNENQSDSFSVAHGFLWIGSCTSQMGQIAIVSFHNSSPKVIECFNVESRVLCMVYVPAEDRPREPEGGGRVLGVPAVCLGTEEGSISIYKSSQGCKKVRLQHFFTPEKSTVMSLACTAQSLYAGLVNGAVAVYARADDGSWNSEPQTVIKLGVLPVRSLLLMEDTLWAASGGQVFIISVETLAVEGQLEAHQEEGMVVSHMAIAGVGIWVAFTSGSTLRLFHTETLKHLQDVNIATPVHHMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGLVSHHAHHGPVKFLVVAAAALKADKDRPRDSPPPGADPQDDEQRDVPSSEGPGLCMGRGGPDAVWLGTSPGSITQGSDVSSSSGSPTPSQGSGSLEPRPEESLAQDLLRLPCTSPSRGRRARRPRASSVLVACGGQGHRRVSRKARPQRPEELASSLMVWQIPLLHV", "length": 1327, "header": "tr|A0A3Q1LS11-1|E1BH05_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 10 OS=Bos taurus OX=9913 GN=ARHGEF10 PE=4 SV=1 CANONICAL=E1BH05-1" }, "locus": { "chromosome": "27", "start_pos": 1407796, "end_pos": 1359222, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070320.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070320.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059985.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059985.1" } ] } }, { "isoform_ac": "E1BH05-1", "url": "https://www.uniprot.org/uniprotkb/E1BH05/entry#E1BH05-1", "sequence": { "sequence": "MDQPGPPAPAREENEVKYDTNNNEEEEEEGEQLDLDSGDEAPEADRQAPGSAEAGDAGADAPATAATAATAGPCASSGHHPGTSQPTCGLDRPGEGCEKGPGVEPLKPGVPSRVNPYSVIDITPLQEDQPPPPDPDAEGEGGGLHVPSGYLVPVPCGYAVPSSLPLLLPAYTSPVLPAPPADPAETQEAAEDSQLNSLSSEDPANSEDPDQKEDSALARWVADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGHSSLEYGWSSSEFESYEEQSDSESRSGVPRSFLRGDHRKQLSHDLTRLKEHYERKMRELMANTVGAVEIQQLKHKHELKMQKLVRAAREGTKDGLEKTKAAVKRGRSFIRTKSFISADHRSCLEEEQNVFIDVDCKHPEAILTPMPEGLSQQQVVRRYILGSIVDSEKNYVDALKRILEQYEKPLWEMEPKVLSERKLRTVFFRVKEVLQCHCLLQIALAGRVAEWDSVEMIGDVFVASFSKSMVLDAYSEYVNNFSTAVAILKKTCATKPAFLEFLKQCQESSPDRVTLHSLMTKPIQRFPQFILLLQDMLKNTPRGHPDRLPLQMALTELETLAEKLNERKRDADQRCEIKQIAKAINERYLNKLLSSGSRYLIRSDDVIETVYNDRGEIMKTKERRLFMLNDVLMCATVSTRAPSSRSASHDGGAVTSGQRYLLKWSVPLGQAEVVEYGGGEGVAEGGRCPTGPAPESLLAASTKPHRVYVGPGQLYQDLQNLLHDLSVIGHITQLVGNLKGNYQNLNPLVAQDWMSGLQRLILKKEEEIRAADCCRVQLQLPGKQDKSGRPTFFTAVFNTFTPAIKESWINSLQMAKLALEEENHLGWFCVEDDGNQIRKERHPLLLGHMPVTVAKQQEFKIECAVYNPEPYLNNENQSDSFSVAHGFLWIGSCTSQMGQIAIVSFHNSSPKVIECFNVESRVLCMVYVPAEDRPREPEGGGRVLGVPAVCLGTEEGSISIYKSSQGCKKVRLQHFFTPEKSTVMSLACTAQSLYAGLVNGAVAVYARADDGSWNSEPQTVIKLGVLPVRSLLLMEDTLWAASGGQVFIISVETLAVEGQLEAHQEEGMVVSHMAIAGVGIWVAFTSGSTLRLFHTETLKHLQDVNIATPVHHMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGLVSHHAHHGPVKFLVVAAAALKADKDRPRDSPPPGADPQDDEQRDVPSSEGPGLCMGRGGPDAVWLGTSPGSITQGSDVSSSSGSPTPSQGSGSLEPRPEESLAQDLLRLPCTSPSRGRRARRPRASSVLVACGGQGHRRVSRKARPQRPEELASSLMVWQIPLLHV", "length": 1366, "header": "tr|E1BH05-1|E1BH05_BOVIN Isoform 1 of Rho guanine nucleotide exchange factor 10 OS=Bos taurus OX=9913 GN=ARHGEF10 PE=4 SV=3 CANONICAL=E1BH05-1" }, "locus": { "chromosome": "27", "start_pos": 1407796, "end_pos": 1359222, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011327.8", "url": "https://www.ensembl.org/id/ENSBTAT00000011327.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011327.6", "url": "https://www.ensembl.org/id/ENSBTAP00000011327.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1286, "start_aa": "Thr", "end_pos": 1286, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1286", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100138303", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138303", "resource": "KEGG Pathway" }, { "id": "R-BTA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-BTA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-BTA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XDF6-1", "protein_name": "Rho guanine nucleotide exchange factor 10", "gene_name": "ARHGEF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDTEEFPPPPPEVLEHEPKAVSTNDEEEDEGELFDFDSGDEIPEADRQALVPPPPDPGSNTEHQEANVTAKGADNLEKSEKLQASEPTAEDAPRKVNPYSVINISPMQEKDPSSSPDPSPQDEPASPNVSSGYSVPVPCGYAVPSNLPLMLPAYSSPVIIRSVSVDEEAGMQSATEECHCNSLNSEEPQNSEDNQVKREDDALAKWVADPANTEWMENPDEVIYDDVPRENSDSEPEEMIYDDVENGDDGGNSSLEYGWSSSEFESYEEQSDSECKNGIPSSFLRGNHKRHLSHDLTRLKEHYEKKMKDLMANTVGAVEIQQLKQKHELKMQKLMRAAREGTKDGLEKTKAAVKKGRSFIRTKSFISQDHRSSCLEEEELNLFIDVDCVHTEAIMTPMPEGLSQQQVVRRYILGSVVDSEKNYVDALKRILEQYEKPLSEMEPKLLSERKLKMVFYRIKEILQCHSMFQIALASRVSEWDSVEMIGDVFVASFSKSMVLDAYSEYVNNFSTAVGILKKTCATKPAFLDFLKQCQESSPDRITLYGLMMKPIQRFPQFILLLQDMLKNTSKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEIKQIAKAMNERYLNKLLSSGNRYLIRTDDMVETVYNDKGEIIKTKERRLFMLNDVLMCATVNVRTSYESSGTMTTGQRYLLKWSVPLGQVEVIEYGSSEGQGENCRFPPQHSAENVIVNSKPNKLYMGPGQLYHDLQNLLHDLNVVGQISQLIGSLKGNYQNLNQSVAHDWTSGLQKLILKKEDEIRAADRCRIQLQLPGKQDKSGRPTFFTAVFNTFTPAIKQSWINNLQMAKLALAEDNLLGWFCVEDDGNQIKKEKHPLLVRHMPVMMAKQQEFKIECAAYNPELYLSGETDSDSCSMEHGFLWIGSCTNQMGQIAIVSFQSSGPKVIECFNVESRILCMVYIPEEEKIKEINMSLNSENVPTKASNVPTICLGMEEGSISIYKSCQGSKKIRLQHFFTPEKSTVMSLTYMSQYLFAGLVNGNIAIYTKAEDGTWNMEPQKTVKLGVLPVRSLLVMEDTIWAACGGQIFIISTVTHFIESHFEAHQEEGMVISHMAVAGVGVWIAFTSGSTLRLFHTETLKHLQDINIATPVHNMLPGQQRVSVTSLLVCHGLLLVGTNLGIIVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFLVMATSLNKKNKNKLRNSLPRGSESKDKDQRNVLHNDRPGSSNGSNPDTSVWLGGSAGSIAQKSDLSSSSGSLTSSSLEHRPEDSNIYELLKDQNISFKNKRQRSKKMKASSVLVISGGQGHRRVNKKTKQQRQDELVSSVMVWQIPLLNI", "length": 1352 }, "evidence": [ { "id": "E1BH05", "url": "https://omabrowser.org/oma/group/E1BH05/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "M0R3X3-1", "protein_name": "Rho guanine nucleotide exchange factor 10", "gene_name": "Arhgef10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQGEASPPVPAEHEVKCDTSNNEEEGELFDFESGDEVPEADRQAPTADDGTGVAEADGADENTSPDGTGVAEADGADENTSPDGTRVDEADGADENTSPAGNGTGAESVPEAEPEKLVVPIKVNPYSVIDITPFQEDQPPSPDANPEEEGVGLRVPSGYCVPVPCGYAVPSNLPLLLPTYSSQIIIRAQSVEEEVAAEVAGDGQCNSLSSEDLPHSGDQGSQEGSALARWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGGEGGNSSLEYGWSSSEFESYEEPSDSEGKNGIPRSFLRSNHKKQLSHDLTRFKAHCEEKMRGLVASTVGAMEAQQRQEWKMQRLMKAAKEGTRDGLEKTKAAVKRGRSFIRTKSLVSQDHRYYFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLRMVFYRIKEILQCHSMFQIALASRVSEWDAVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEIKQIAKAINERYLNKLLSSGNRYLVRSDDVIETVYNDRGEIVKTKQRRIFMLNDVLMCATASSRNSHESHAMMNQRYLLKWSVPLGQVDVIEYSGSSGTGDHSRHHTAHSPESLAVVANVKPHKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLNQSVAHDWTSGLQQLILRKEDAIRAADRCRIQLQLPGKQDKSGRPTFFTAVFNTFTPAIKESWVSSLQMAKLALEEENHMGWFCVDDDGSLAKKETHPLLVGHTSVMVAKQPEFKIECAAYNPEPYPSNDNQPASPSTARGFLWIGSCSNQMGQVAIVSFQSANPKVIECFNVESRILCMIYIPAEESKPQEPADTKDPEATASRAPHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYTPDKSTVMSLACSPHGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASVETHTVENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVTATAFQNKDRARDRPRSSSELQDEDPKDLLCGEEGTSCLGQTDTSTAVWLGDSLGLTAQNDLSSSSGSLSHGSSSLEHRSVDSSLCDLLRDPSAFPRSRAQSSRRARASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLGM", "length": 1373 }, "evidence": [ { "id": "E1BH05", "url": "https://omabrowser.org/oma/group/E1BH05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15013-1", "protein_name": "Rho guanine nucleotide exchange factor 10", "gene_name": "ARHGEF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPPGFLSRAPSLNRAERGIWSCSMDQREPLPPAPAENEMKYDTNNNEEEEGEQFDFDSGDEIPEADRQAPSAPETGGAGASEAPAPTGGEDGAGAETTPVAEPTKLVLPMKVNPYSVIDITPFQEDQPPTPVPSAEEENVGLHVPCGYLVPVPCGYAVPSNLPLLLPAYSSPVIICATSLDEEAETPEVTEDRQPNSLSSEEPPTSEDQVGREDSALARWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECKNGIPRSFLRSNHKKQLSHDLTRLKEHYEKKMRDLMASTVGVVEIQQLRQKHELKMQKLVKAAKDGTKDGLERTRAAVKRGRSFIRTKSLIAQDHRSSLEEEQNLFIDVDCKHPEAILTPMPEGLSQQQVVRRYILGSVVDSEKNYVDALKRILEQYEKPLSEMEPKVLSERKLKTVFYRVKEILQCHSLFQIALASRVSEWDSVEMIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPAFLEFLKQEQEASPDRTTLYSLMMKPIQRFPQFILLLQDMLKNTSKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSGSRYLIRSDDMIETVYNDRGEIVKTKERRVFMLNDVLMCATVSSRPSHDSRVMSSQRYLLKWSVPLGHVDAIEYGSSAGTGEHSRHLAVHPPESLAVVANAKPNKVYMGPGQLYQDLQNLLHDLNVIGQITQLIGNLKGNYQNLNQSVAHDWTSGLQRLILKKEDEIRAADCCRIQLQLPGKQDKSGRPTFFTAVFNTFTPAIKESWVNSLQMAKLALEEENHMGWFCVEDDGNHIKKEKHPLLVGHMPVMVAKQQEFKIECAAYNPEPYLNNESQPDSFSTAHGFLWIGSCTHQMGQIAIVSFQNSTPKVIECFNVESRILCMLYVPVEEKRREPGAPPDPETPAVRASDVPTICVGTEEGSISIYKSSQGSKKVRLQHFFTPEKSTVMSLACTSQSLYAGLVNGAVASYARAPDGSWDSEPQKVIKLGVLPVRSLLMMEDTLWAASGGQVFIISVETHAVEGQLEAHQEEGMVISHMAVSGVGIWIAFTSGSTLRLFHTETLKHLQDINIATPVHNMLPGHQRLSVTSLLVCHGLLMVGTSLGVLVALPVPRLQGIPKVTGRGMVSYHAHNSPVKFIVLATALHEKDKDKSRDSLAPGPEPQDEDQKDALPSGGAGSSLSQGDPDAAIWLGDSLGSMTQKSDLSSSSGSLSLSHGSSSLEHRSEDSTIYDLLKDPVSLRSKARRAKKAKASSALVVCGGQGHRRVHRKARQPHQEELAPTVMVWQIPLLNI", "length": 1369 }, "evidence": [ { "id": "E1BH05", "url": "https://omabrowser.org/oma/group/E1BH05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C033-1", "protein_name": "Rho guanine nucleotide exchange factor 10", "gene_name": "Arhgef10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQGEASPPVPAEHEAKCDTSNNEEEGELFDFDSGDEVPEADRQVPSADDRTRGAEAGGADENTCPAGNGTGAEPAPEAEPAKLVVPTKVNPYSVIDITPLQEDQPSSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAETVGDGQCNSLSSEDLPHSSEQGSQEGSALARWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGEEGGNSSPEYGWSSSEFESYEEPSDSEGKNGIPRSFLRSSHKKQLSHDLTRFKAHCEEKMRGLVASTVGAMEIQQAKQRQERKMQKLMKAAKEGTKDGLEKTKAAVKRGGSFIRTRSLVSQDHRCYFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLRMVFYRVKEILQCHSMFQIALASRVSEWDVVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEIKQIAKAINERYLNKLLSSGNRYLVRSDDVIETVYNDRGEIVKTKQRRIFMLNDVLMCATASSRNSHESHAVMSQRYLLKWSVPLGHVDVIQYNGGSGAGEHCRHHAAHSPESLAVVANAKPHKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLNQSVAHDWTSGLQRLILRKEDAIRAADRCRIQLQLPGKQDKSGRPTFFTAVFNTLTPAIKESWVSSLQMAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVAKQPEFKIECAAYNPEPYLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQGSNPKVIECFNVESRILCMVYIPAEESKPQETTETKDPEATASRAPHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYAPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASVETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVSATAFQNKDRARDSPRSGSELQDEDPKDLLCSEEGPSCPGQPDTYTSVWLGDSLGLPTQKNDLSSSSGSLNLSHGSSSLEHRSVDSSLCDLLRDPSASPRSRPQGSRRARASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLGM", "length": 1345 }, "evidence": [ { "id": "E1BH05", "url": "https://omabrowser.org/oma/group/E1BH05/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BH05", "url": "https://www.uniprot.org/uniprotkb/E1BH05" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BH05", "url": "https://www.uniprot.org/uniprotkb/E1BH05" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "E1BH05", "url": "https://www.uniprot.org/uniprotkb/E1BH05" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "E1BH05", "url": "https://www.uniprot.org/uniprotkb/E1BH05" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "E1BH05", "url": "https://www.uniprot.org/uniprotkb/E1BH05" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "E1BH05", "url": "https://www.uniprot.org/uniprotkb/E1BH05" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": 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"header": "tr|E1BGG6-1|E1BGG6_BOVIN Isoform 1 of Regulatory factor X5 OS=Bos taurus OX=9913 GN=RFX5 PE=3 SV=2 CANONICAL=E1BGG6-1" }, "locus": { "chromosome": "3", "start_pos": 19468603, "end_pos": 19463915, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023377.5", "url": "https://www.ensembl.org/id/ENSBTAT00000023377.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023377.3", "url": "https://www.ensembl.org/id/ENSBTAP00000023377.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "", "database": "GlyGen", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BGG6", "url": "https://www.uniprot.org/uniprotkb/E1BGG6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BGG6", "url": "https://www.uniprot.org/uniprotkb/E1BGG6" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "E1BGG6", "url": "https://www.uniprot.org/uniprotkb/E1BGG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BGG6", "url": "https://www.uniprot.org/uniprotkb/E1BGG6" } ], "pmid": "" }, { 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{ "id": "PS51526", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51526" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RFX-type winged-helix", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 225, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 250 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 537, "end_pos": 539 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGX4-1", "uniprot_ac": "E1BGX4", "uniprot_id": "E1BGX4_BOVIN", "mass": { "chemical_mass": 28149.0, "monoisotopic_mass": 28149.0 }, "refseq": { "ac": "NP_001179061", "name": "WW domain-binding protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179061" }, "gene_names": [ { "name": "WBP2", "type": "recommended", "evidence": [ { "id": "E1BGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ] }, { "name": "WBP2", "type": "synonym", "evidence": [ { "id": "NP_001179061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179061" } ] } ], "protein_names": [ { "name": "WW domain binding protein 2", "type": "synonym", "evidence": [ { "id": "E1BGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX4/entry#names_and_taxonomy" } ] }, { "name": "WW domain-binding protein 2", "type": "synonym", "evidence": [ { "id": "NP_001179061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179061" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "WBP2", "url": "https://www.uniprot.org/uniprotkb/E1BGX4", "locus": { "chromosome": "19", "start_pos": 55768270, "end_pos": 55761584, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008634", "url": "https://www.ensembl.org/id/ENSBTAG00000008634" } ] } } ], "crossref": [ { "id": "E1BGX4", "url": "https://alphafold.ebi.ac.uk/entry/E1BGX4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008634", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008634", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "507060", "url": "https://www.ncbi.nlm.nih.gov/gene/507060", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507060", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507060", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYPGINA", "url": "https://omabrowser.org/oma/group/PYPGINA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LZT9", "url": "https://www.orthodb.org/?gene=A0A3Q1LZT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BGX4", "url": "https://www.orthodb.org/?gene=E1BGX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31606", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31606", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31606:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31606:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179061", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179061", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZT9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXF5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGX4-1", "url": "https://www.uniprot.org/uniprotkb/E1BGX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALNKNHSEGGGVIVNNTESILMSYDHVELTFSDMRNVPEAFKGTKKGTVYLTPYRVIFLSKARDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFMSGGAIEFGQRMLQVASQASRGEAPSGAYGYSYMPSGAYVFPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTSAAEAKAAEAAASAYYNPGNPHNVYMPTNQPPPPPYYPPEDKKTQ", "length": 261, "header": "tr|E1BGX4-1|E1BGX4_BOVIN Isoform 1 of WW domain binding protein 2 OS=Bos taurus OX=9913 GN=WBP2 PE=4 SV=3 CANONICAL=E1BGX4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LZT9-1", "url": "https://www.uniprot.org/uniprotkb/E1BGX4/entry#A0A3Q1LZT9-1", "sequence": { "sequence": "MALNKNHSEGGGVIVNNTESILMSYDHVELTFSDMRNVPEAFKGTKKGTVYLTPYRVIFLSKARDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFMSGGAIEFGQRMLQVASQASRGEAPSGAYGYSYMPSGAYVFPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTSAEPASTTSLLPPRR", "length": 231, "header": "tr|A0A3Q1LZT9-1|E1BGX4_BOVIN Computationally mapped isoform of WW domain binding protein 2 OS=Bos taurus OX=9913 GN=WBP2 PE=4 SV=2 CANONICAL=E1BGX4-1" }, "locus": { "chromosome": "19", "start_pos": 55768019, "end_pos": 55761636, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075188.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075188.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066411.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066411.2" } ] } }, { "isoform_ac": "A0AAA9TXF5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGX4/entry#A0AAA9TXF5-1", "sequence": { "sequence": "MALNKNHSEGGGVIVNNTESILMSYDHVELTFSDMRNVPEAFKGTKKGTVYLTPYRVIFLSKARDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFMSGGAIEFGQRMLQVASQEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTSAAEAKAAEAAASAYYNPGNPHNVYMPTNQPPPPPYYPPEDKKTQ", "length": 216, "header": "tr|A0AAA9TXF5-1|E1BGX4_BOVIN Computationally mapped isoform of WW domain binding protein 2 OS=Bos taurus OX=9913 GN=WBP2 PE=4 SV=1 CANONICAL=E1BGX4-1" }, "locus": { "chromosome": "19", "start_pos": 55768032, "end_pos": 55761636, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128425.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128425.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101328.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101328.1" } ] } }, { "isoform_ac": "E1BGX4-1", "url": "https://www.uniprot.org/uniprotkb/E1BGX4/entry#E1BGX4-1", "sequence": { "sequence": "MALNKNHSEGGGVIVNNTESILMSYDHVELTFSDMRNVPEAFKGTKKGTVYLTPYRVIFLSKARDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFMSGGAIEFGQRMLQVASQASRGEAPSGAYGYSYMPSGAYVFPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTSAAEAKAAEAAASAYYNPGNPHNVYMPTNQPPPPPYYPPEDKKTQ", "length": 261, "header": "tr|E1BGX4-1|E1BGX4_BOVIN Isoform 1 of WW domain binding protein 2 OS=Bos taurus OX=9913 GN=WBP2 PE=4 SV=3 CANONICAL=E1BGX4-1" }, "locus": { "chromosome": "19", "start_pos": 55768032, "end_pos": 55761636, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011385.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011385.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011385.6", "url": "https://www.ensembl.org/id/ENSBTAP00000011385.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507060", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507060", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HTV2-1", "protein_name": "WW domain-binding protein 2", "gene_name": "Wbp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFLSKGKDAMQSFMMPFYLMKDCEIKQPVFGANFIKGTVKAEAGGGWEGAASYKLTFTAGGAIEFGQRMLQVASQASRGEAPNGAYGYPYMPSGAYVFPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPSAPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ", "length": 261 }, "evidence": [ { "id": "E1BGX4", "url": "https://omabrowser.org/oma/group/E1BGX4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P97765-1", "protein_name": "WW domain-binding protein 2", "gene_name": "Wbp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFLSKGKDAMQSFMMPFYLMKDCEIKQPVFGANFIKGIVKAEAGGGWEGSASYKLTFTAGGAIEFGQRMLQVASQASRGEVPNGAYGYPYMPSGAYVFPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPSAPATPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ", "length": 261 }, "evidence": [ { "id": "E1BGX4", "url": "https://omabrowser.org/oma/group/E1BGX4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R478-1", "protein_name": "WW domain-binding protein 2", "gene_name": "Wbp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFLSKGKDAMRSFMMPFYLMKDCEVKQPVFGANFIKGTVKAEAGGGWEGSASYKLTFTAGGAIEFGQQMLQVASQASRGEVPNGAYGYPYMPSGAYVFPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVVSGPSAPPTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ", "length": 262 }, "evidence": [ { "id": "E1BGX4", "url": "https://omabrowser.org/oma/group/E1BGX4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q969T9-1", "protein_name": "WW domain-binding protein 2", "gene_name": "WBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFLSKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAGGAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ", "length": 261 }, "evidence": [ { "id": "E1BGX4", "url": "https://omabrowser.org/oma/group/E1BGX4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VU19-1", "protein_name": "WW domain binding protein 2, isoform E", "gene_name": "Wbp2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSVNTAHANNGVLIHAGEYILLHSDSVSMEFSGQDNPIFKGSKGGRIYLTSHRMIFNSKKSSDSMQSFSAPFVALSDVEIEQPVFGANYIKGKVRAQPNGNYVGEVKFKLHFKAGGAIEYGQALLRSAKTAMNNYHRGGLAGDDPPPYQPAGSWNEAPPPAYQPPPGYYGWLPQHDAFSGPAPNTVYMSDNPPPYPGIAPPAHQPAPQQPQAPSSNEPNWYGFSAPPPQQQQQQPGYGPQGWAGGYVQPPPYASCAPNCPPQPPYAAPAQTYNGPQPYGGYGNVPGGFNTPGFQQPNGNPNGYPGGPPPPGQQAAGAAGGAAASGASFMGFSLPPGNSKEAEAAASAYNTPYNQGGPSGSGNNDLPPSYNNLPPSYDDASKKNH", "length": 384 }, "evidence": [ { "id": "E1BGX4", "url": "https://omabrowser.org/oma/group/E1BGX4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "response to progesterone", "id": "GO:0032570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032570", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "positive regulation of intracellular estrogen receptor signaling pathway", "id": "GO:0033148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033148", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "establishment of protein localization to chromatin", "id": "GO:0071169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071169", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" }, { "name": "progesterone receptor signaling pathway", "id": "GO:0050847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050847", "evidence": [ { "database": "UniProtKB", "id": "E1BGX4", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGX4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 261, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGX4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGX4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX4" }, { "id": "PF02893", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GRAM", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 131, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BID7-1", "uniprot_ac": "E1BID7", "uniprot_id": "E1BID7_BOVIN", "mass": { "chemical_mass": 57493.0, "monoisotopic_mass": 57493.0 }, "refseq": { "ac": "XP_024853944", "name": "E3 ubiquitin-protein ligase TRIM69 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853944" }, "gene_names": [ { "name": "TRIM69", "type": "recommended", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] }, { "name": "TRIM69", "type": "synonym", "evidence": [ { "id": "XP_024853944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853944" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase TRIM69", "type": "recommended", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase TRIM69 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024853944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853944" } ] }, { "name": "RING finger protein 36", "type": "synonym", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase TRIM69", "type": "synonym", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7/entry#names_and_taxonomy" } ] }, { "name": "Tripartite motif-containing protein 69", "type": "synonym", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "E3 ubiquitin ligase that plays an important role in antiviral immunity by restricting different viral infections including dengue virus or vesicular stomatitis indiana virus. Ubiquitinates viral proteins such as dengue virus NS3 thereby limiting infection. In addition, acts as a key mediator of type I interferon induced microtubule stabilization by directly associating to microtubules independently of its E3 ligase activity. Also plays a role in cataract formation together with TP53. Mechanistically, inhibits UVB-induced cell apoptosis and reactive oxygen species (ROS) production by inducing TP53 ubiquitination. Regulates centrosome dynamics and mitotic progression by ubiquitinating STK3/MST2; leading to its redistribution to the perinuclear cytoskeleton and subsequent phosphorylation by PLK1.", "evidence": [ { "database": "UniProtKB", "id": "E1BID7", "url": "https://www.uniprot.org/uniprotkb/E1BID7#function" }, { "database": "UniProtKB", "id": "ARBA00057076", "url": "https://www.uniprot.org/uniprotkb/ARBA00057076#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BID7", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TRIM69", "url": "https://www.uniprot.org/uniprotkb/E1BID7", "locus": { "chromosome": "10", "start_pos": 103195439, "end_pos": 103159674, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007518", "url": "https://www.ensembl.org/id/ENSBTAG00000007518" } ] } } ], "crossref": [ { "id": "E1BID7", "url": "https://alphafold.ebi.ac.uk/entry/E1BID7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007518", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007518", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15818", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15818", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16611", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16611", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "618372", "url": "https://www.ncbi.nlm.nih.gov/gene/618372", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618372", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618372", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024853944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853944", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M074", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M074-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M074-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZR8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BID7", "url": "https://www.uniprot.org/uniprotkb/E1BID7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BID7-1", "url": "https://www.uniprot.org/uniprotkb/E1BID7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVSSNLSSKTDTDSDSYAEVNDVITQISSKVQIQDITTELHCPLCNDWFRDALMLSCGHNFCQSCIQNFWKQQANETFCPECKMLCQYSNCTFNLVLEKLVEKIKKLPLLKGHPRCPEHGENLKLFSKPDGRLICFQCKDARLSVGQSKEFLQISDAVHFFTEELTIHQGQLEATLKELQSLKNMQKDAIAAHKENKLHLQQHISLEFLKLHQFLHSKEKDLLSELREEGKALNEEMELNLSHIQEQCLLAKEMLVSIQARMEQQNPFDFLKDITPLLDSLEQGMRMLTPKELVSRKLSPGVFKGPIQYTIWRDMQSTLSPGLSPLTLDPKTAHPNLVLSKNRTSVWHGDIKQLMPDDPERFDSSVAVLGSKGFTSGKWYWEVEVAKKTKWTVGVVRESILRKGSCPLTPEQGFWLLRLRNQTDLKALDFPSCSLKLTNNLNKVGIYLDYEGGQVSFYNAKTMTHIYTFSSVFMEKLYPYFCPCLNDGGENKEPLHILHPQ", "length": 502, "header": "tr|E1BID7-1|E1BID7_BOVIN Isoform 1 of E3 ubiquitin-protein ligase TRIM69 OS=Bos taurus OX=9913 GN=TRIM69 PE=3 SV=3 CANONICAL=E1BID7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M074-1", "url": "https://www.uniprot.org/uniprotkb/E1BID7/entry#A0A3Q1M074-1", "sequence": { "sequence": "MEEELTIHQGQLEATLKELQSLKNMQKDAIAAHKDITPLLDSLEQGMRMLTPKELVSRKLSPGVFKGPIQYTIWRDMQSTLSPGLSPLTLDPKTAHPNLVLSKNRTSVWHGDIKQLMPDDPERFDSSVAVLGSKGFTSGKWYWEVEVAKKTKWTVGVVRESILRKGSCPLTPEQGFWLLRLRNQTDLKALDFPSCSLKLTNNLNKVGIYLDYEGGQVSFYNAKTMTHIYTFSSVFMEKLYPYFCPCLNDGGENKEPLHILHPQ", "length": 263, "header": "tr|A0A3Q1M074-1|E1BID7_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM69 OS=Bos taurus OX=9913 GN=TRIM69 PE=3 SV=2 CANONICAL=E1BID7-1" }, "locus": { "chromosome": "10", "start_pos": 103195381, "end_pos": 103159829, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071222.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071222.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061357.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061357.2" } ] } }, { "isoform_ac": "A0AAA9RZR8-1", "url": "https://www.uniprot.org/uniprotkb/E1BID7/entry#A0AAA9RZR8-1", "sequence": { "sequence": "MEEELTIHQGQLEATLKELQSLKNMQKDAIAAHKENKLHLQQHISLEFLKLHQFLHSKEKDLLSELREEGKALNEEMELNLSHIQEQCLLAKEMLVSIQARMEQQNPFDFLKDITPLLDSLEQGMRMLTPKELVSRKLSPGVFKGPIQYTIWRDMQSTLSPGLSPLTLDPKTAHPNLVLSKNRTSVWHGDIKQLMPDDPERFDSSVAVLGSKGFTSGKWYWEVEVAKKTKWTVGVVRESILRKGSCPLTPEQGFWLLRLRNQTDLKALDFPSCSLKLTNNLNKVGIYLDYEGGQVSFYNAKTMTHIYTFSSVFMEKLYPYFCPCLNDGGENKEPLHILHPQ", "length": 341, "header": "tr|A0AAA9RZR8-1|E1BID7_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM69 OS=Bos taurus OX=9913 GN=TRIM69 PE=3 SV=1 CANONICAL=E1BID7-1" }, "locus": { "chromosome": "10", "start_pos": 103195381, "end_pos": 103159829, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121574.2", "url": "https://www.ensembl.org/id/ENSBTAT00000121574.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076580.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076580.1" } ] } }, { "isoform_ac": "E1BID7-1", "url": "https://www.uniprot.org/uniprotkb/E1BID7/entry#E1BID7-1", "sequence": { "sequence": "MEVSSNLSSKTDTDSDSYAEVNDVITQISSKVQIQDITTELHCPLCNDWFRDALMLSCGHNFCQSCIQNFWKQQANETFCPECKMLCQYSNCTFNLVLEKLVEKIKKLPLLKGHPRCPEHGENLKLFSKPDGRLICFQCKDARLSVGQSKEFLQISDAVHFFTEELTIHQGQLEATLKELQSLKNMQKDAIAAHKENKLHLQQHISLEFLKLHQFLHSKEKDLLSELREEGKALNEEMELNLSHIQEQCLLAKEMLVSIQARMEQQNPFDFLKDITPLLDSLEQGMRMLTPKELVSRKLSPGVFKGPIQYTIWRDMQSTLSPGLSPLTLDPKTAHPNLVLSKNRTSVWHGDIKQLMPDDPERFDSSVAVLGSKGFTSGKWYWEVEVAKKTKWTVGVVRESILRKGSCPLTPEQGFWLLRLRNQTDLKALDFPSCSLKLTNNLNKVGIYLDYEGGQVSFYNAKTMTHIYTFSSVFMEKLYPYFCPCLNDGGENKEPLHILHPQ", "length": 502, "header": "tr|E1BID7-1|E1BID7_BOVIN Isoform 1 of E3 ubiquitin-protein ligase TRIM69 OS=Bos taurus OX=9913 GN=TRIM69 PE=3 SV=3 CANONICAL=E1BID7-1" }, "locus": { "chromosome": "10", "start_pos": 103195381, "end_pos": 103159829, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009893.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009893.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009893.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009893.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:618372", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618372", "resource": "KEGG Pathway" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BID7", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BID7", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BID7", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BID7", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BID7", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "E1BID7", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1BID7", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ], "pmid": "" }, { "name": "protein localization to centrosome", "id": "GO:0071539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071539", "evidence": [ { "database": "UniProtKB", "id": "E1BID7", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983140" } ] }, { "id": "R-BTA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4I9-1", "E1BJS7-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q1JQA1-1", "Q29RQ5-1", "Q32LN5-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0AAA9RXI4-1", "Q4U5R4-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983147" } ] }, { "id": "R-BTA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983156" } ] }, { "id": "R-BTA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1MAR8", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] } ] }, { "uniprot_ac": "A0A3Q1MLB6", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] } ] }, { "uniprot_ac": "A0A3Q1MLH2", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] } ] }, { "uniprot_ac": "A0A3Q1N3G7", "gene_name": "TRIM36", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] } ] }, { "uniprot_ac": "A0AAA9RXI4", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] } ] }, { "uniprot_ac": "A0AAA9RXX2", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] } ] }, { "uniprot_ac": "A0AAA9RZ14", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] } ] }, { "uniprot_ac": "A0AAA9S100", "gene_name": "MKRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] } ] }, { "uniprot_ac": "A0AAA9TKS8", "gene_name": "RNF217", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] } ] }, { "uniprot_ac": "A0AAA9TWH7", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] } ] }, { "uniprot_ac": "A0AAF6DMH9", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] } ] }, { "uniprot_ac": "A0ABI0NWC8", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] } ] }, { "uniprot_ac": "A0JN74", "gene_name": "TRIM11", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] } ] }, { "uniprot_ac": "A1A4I9", "gene_name": "UFL1", "activity": [ { "ec_number": "2.3.2.-", "activity": "", "evidence": [ { "id": "A1A4I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I9" } ] } ] }, { "uniprot_ac": "A3KN22", "gene_name": "UBE2M", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] } ] }, { "uniprot_ac": "A5D7F8", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] } ] }, { "uniprot_ac": "A5PJC4", "gene_name": "UBE2L6", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] } ] }, { "uniprot_ac": "A5PKG6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] } ] }, { "uniprot_ac": "A6H795", "gene_name": "UBE2W", "activity": [ { "ec_number": "2.3.2.25", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein].", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] } ] }, { "uniprot_ac": "E1B782", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] } ] }, { "uniprot_ac": "E1B7D3", "gene_name": "TRIM39", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] } ] }, { "uniprot_ac": "E1B7G3", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] } ] }, { "uniprot_ac": "E1B7Q7", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] } ] }, { "uniprot_ac": "E1B8R6", "gene_name": "ARIH2", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] } ] }, { "uniprot_ac": "E1BAV2", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] } ] }, { "uniprot_ac": "E1BBN5", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] } ] }, { "uniprot_ac": "E1BBY2", "gene_name": "TRIM41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] } ] }, { "uniprot_ac": "E1BCU1", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] } ] }, { "uniprot_ac": "E1BCW1", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] } ] }, { "uniprot_ac": "E1BH71", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] } ] }, { "uniprot_ac": "E1BID7", "gene_name": "TRIM69", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] } ] }, { "uniprot_ac": "E1BIP5", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] } ] }, { "uniprot_ac": "E1BIW0", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] } ] }, { "uniprot_ac": "E1BJS7", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] } ] }, { "uniprot_ac": "E1BL26", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] } ] }, { "uniprot_ac": "E1BNQ6", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] } ] }, { "uniprot_ac": "E1BNY9", "gene_name": "HUWE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] } ] }, { "uniprot_ac": "F1MBM6", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] } ] }, { "uniprot_ac": "F1MEX6", "gene_name": "RNF19B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] } ] }, { "uniprot_ac": "F1MJ10", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] } ] }, { "uniprot_ac": "F1MJS5", "gene_name": "HECTD3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] } ] }, { "uniprot_ac": "F1MLS5", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] } ] }, { "uniprot_ac": "F1MM41", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] } ] }, { "uniprot_ac": "F1MTS8", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] } ] }, { "uniprot_ac": "F1MWS4", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] } ] }, { "uniprot_ac": "F1MYL0", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] } ] }, { "uniprot_ac": "F1N1X8", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] } ] }, { "uniprot_ac": "F1N3I3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] } ] }, { "uniprot_ac": "F1N495", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] } ] }, { "uniprot_ac": "F1N5G3", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] } ] }, { "uniprot_ac": "F1N645", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] } ] }, { "uniprot_ac": "F1N6G5", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] } ] }, { "uniprot_ac": "F1N703", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] } ] }, { "uniprot_ac": "F1N7A0", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] } ] }, { "uniprot_ac": "P61085", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] } ] }, { "uniprot_ac": "Q0II22", "gene_name": "RNF126", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] } ] }, { "uniprot_ac": "Q0P5K3", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] } ] }, { "uniprot_ac": "Q17QG5", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] } ] }, { "uniprot_ac": "Q1JQA1", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] } ] }, { "uniprot_ac": "Q1RML1", "gene_name": "UBE2S", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] } ] }, { "uniprot_ac": "Q1RMW1", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] } ] }, { "uniprot_ac": "Q1RMX2", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] } ] }, { "uniprot_ac": "Q29RQ5", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] } ] }, { "uniprot_ac": "Q2T9X7", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] } ] }, { "uniprot_ac": "Q2TA03", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] } ] }, { "uniprot_ac": "Q2TA10", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] } ] }, { "uniprot_ac": "Q32L27", "gene_name": "UBE2Q2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] } ] }, { "uniprot_ac": "Q32LN1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] } ] }, { "uniprot_ac": "Q32LN5", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] } ] }, { "uniprot_ac": "Q32P99", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] } ] }, { "uniprot_ac": "Q32PA5", "gene_name": "UBE2C", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] } ] }, { "uniprot_ac": "Q3MHP1", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] } ] }, { "uniprot_ac": "Q4U5R4", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] } ] }, { "uniprot_ac": "Q5E9J6", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] } ] }, { "uniprot_ac": "Q7YRV4", "gene_name": "TRIM21", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BID7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 502, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BID7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BID7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 307, "end_pos": 502, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 84, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 241, "end_pos": 243 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 6, "end_pos": 8 }, { "start_pos": 76, "end_pos": 78 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BF48-1", "uniprot_ac": "E1BF48", "uniprot_id": "E1BF48_BOVIN", "mass": { "chemical_mass": 46080.0, "monoisotopic_mass": 46080.0 }, "refseq": {}, "gene_names": [ { "name": "CD177", "type": "recommended", "evidence": [ { "id": "E1BF48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF48" } ] } ], "protein_names": [ { "name": "CD177 molecule", "type": "synonym", "evidence": [ { "id": "E1BF48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF48/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BF48", "url": "https://www.uniprot.org/uniprotkb/E1BF48" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CD177", "url": "https://www.uniprot.org/uniprotkb/E1BF48", "locus": { "chromosome": "18", "start_pos": 51557281, "end_pos": 51546417, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002976", "url": "https://www.ensembl.org/id/ENSBTAG00000002976" } ] } } ], "crossref": [ { "id": "E1BF48", "url": "https://alphafold.ebi.ac.uk/entry/E1BF48", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002976", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002976", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23623", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23623", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23624", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23624", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23637", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23637", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR016054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HVCREKD", "url": "https://omabrowser.org/oma/group/HVCREKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16529", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16529", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16529:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16529:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00021", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00021", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-202733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9769739", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769739", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M1B6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1B6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF48", "url": "https://www.uniprot.org/uniprotkb/E1BF48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF48-1", "url": "https://www.uniprot.org/uniprotkb/E1BF48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPALLLALLGITLALPGARALNCYSGVAETIRNVSEQPFRWTTSQVNCGEGLGCQEMVLITQNDPLLYLVLIKGCTQAANQEARVTDHRAGPGLSIVSYTRVCRENLCNDLSTSLPLWTPLPRTVPGSVRCPVCLSGEGCLSAPEMTCPAKSSHCYNGVLQLTAGDPPGGSSTSRLKVQGCISQAGCNLLNGTQEVGPISLWETCIPKGALTCYRGIMLQMSPNLSQDPVDWSTTTEQQCNPGEVCQETLLLIDVGPRSILLGSKGCSQVNIQGDFMHSRPPGVLVASYARVCSSDYCNSAASSSVLVNALPRPAPPAPGHLQCPVCLALGSCSQSSNVMCPKGTSHCYKGQIFLRGGGLTAPVDIQGCVAHPSSTLLGRRWSIGVFTVTETREGGAEVDEPLISSGAAPGPSLAWAVGLALALWCGAPSLLTLFPQDP", "length": 440, "header": "tr|E1BF48-1|E1BF48_BOVIN Isoform 1 of CD177 molecule OS=Bos taurus OX=9913 GN=CD177 PE=1 SV=3 CANONICAL=E1BF48-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M1B6-1", "url": "https://www.uniprot.org/uniprotkb/E1BF48/entry#A0A3Q1M1B6-1", "sequence": { "sequence": "MSPALLLALLGITLALPGARALNCYSGVAETIRNVSEQPFRWTTSQVNCGEGLGCQEMVLITQNDPLLYLVLIKGCTQAANQEARVTDHRAGPGLSIVSYTRVCRENLCNDLSTSLPLWTPLPRTVPGSVRCPVCLSGEGCLSAPEMTCPAKSSHCYNGVLQLTAGDPPGGSSTSRLKVQGCISQAGCNLLNGTQEVGPISLWETCIPKGECHGDKTKHFGRGCQETEKVRGPRSILLGSKGCSQVNIQGDFMHSRPPGVLVASYARVCSSDYCNSAASSSVLVNALPRPAPPAPGHLQCPVCLALGSCSQSSNVMCPKGTSHCYKGQIFLRGGGLTAPVDIQGCVAHPSSTLLGRRWSIGVFTVTETREGGAEVDEPLISSGAAPGPSLAWAVGLALALWCGAPSLLTLFPQDP", "length": 415, "header": "tr|A0A3Q1M1B6-1|E1BF48_BOVIN Computationally mapped isoform of CD177 molecule OS=Bos taurus OX=9913 GN=CD177 PE=1 SV=1 CANONICAL=E1BF48-1" }, "locus": { "chromosome": "18", "start_pos": 51557006, "end_pos": 51546449, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085706.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085706.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063495.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063495.1" } ] } }, { "isoform_ac": "E1BF48-1", "url": "https://www.uniprot.org/uniprotkb/E1BF48/entry#E1BF48-1", "sequence": { "sequence": "MSPALLLALLGITLALPGARALNCYSGVAETIRNVSEQPFRWTTSQVNCGEGLGCQEMVLITQNDPLLYLVLIKGCTQAANQEARVTDHRAGPGLSIVSYTRVCRENLCNDLSTSLPLWTPLPRTVPGSVRCPVCLSGEGCLSAPEMTCPAKSSHCYNGVLQLTAGDPPGGSSTSRLKVQGCISQAGCNLLNGTQEVGPISLWETCIPKGALTCYRGIMLQMSPNLSQDPVDWSTTTEQQCNPGEVCQETLLLIDVGPRSILLGSKGCSQVNIQGDFMHSRPPGVLVASYARVCSSDYCNSAASSSVLVNALPRPAPPAPGHLQCPVCLALGSCSQSSNVMCPKGTSHCYKGQIFLRGGGLTAPVDIQGCVAHPSSTLLGRRWSIGVFTVTETREGGAEVDEPLISSGAAPGPSLAWAVGLALALWCGAPSLLTLFPQDP", "length": 440, "header": "tr|E1BF48-1|E1BF48_BOVIN Isoform 1 of CD177 molecule OS=Bos taurus OX=9913 GN=CD177 PE=1 SV=3 CANONICAL=E1BF48-1" }, "locus": { "chromosome": "18", "start_pos": 51557006, "end_pos": 51546449, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003875.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003875.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003875.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003875.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-202733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-202733", "resource": "Reactome", "description": "Cell surface interactions at the vascular wall" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-BTA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RMW7-1", "protein_name": "CD177 molecule", "gene_name": "CD177", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"MSAVLLLALLGFILPLPGVQALLCQFGTVQHVWKVSDLPRQWTPKNTSCDSGLGCQDTLMLIESGPQVSLVLSKGCTEAKDQEPRVTEHRMGPGLSLISYTFVCRQEDFCNNLVNSLPLWAPQPPADPGSLRCPVCLSMEGCLEGTTEEICPKGTTHCYDGLLRLRGGGIFSNLRVQGCMPQPGCNLLNGTQEIGPVGMTENCNRKDFLTCHRGTTIMTHGNLAQEPTDWTTSNTEMCEVGQVCQETLLLLDVGLTSTLVGTKGCSTVGAQNSQKTTIHSAPPGVLVASYTHFCSSDLCNSASSSSVLLNSLPPQAAPVPGDRQCPTCVQPLGTCSSGSPRMTCPRGATHCYDGYIHLSGGGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSAREKRDVQPPASQHEGGGAEGLESLTWGVGLALAPALWWGVVCPSC", "length": 437 }, "evidence": [ { "id": "E1BF48", "url": "https://omabrowser.org/oma/group/E1BF48/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BF48", "url": "https://www.uniprot.org/uniprotkb/E1BF48" } ], "pmid": "" }, { "name": "plasma membrane raft", "id": "GO:0044853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044853", "evidence": [ { "database": "UniProtKB", "id": "E1BF48", "url": "https://www.uniprot.org/uniprotkb/E1BF48" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "leukocyte cell-cell adhesion", "id": "GO:0007159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007159", "evidence": [ { "database": "UniProtKB", "id": "E1BF48", "url": "https://www.uniprot.org/uniprotkb/E1BF48" } ], "pmid": "" }, { "name": "regulation of integrin-mediated signaling pathway", "id": "GO:2001044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001044", "evidence": [ { "database": "UniProtKB", "id": "E1BF48", "url": "https://www.uniprot.org/uniprotkb/E1BF48" } ], "pmid": "" }, { "name": "positive regulation of neutrophil degranulation", "id": "GO:0043315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043315", "evidence": [ { "database": "UniProtKB", "id": "E1BF48", "url": "https://www.uniprot.org/uniprotkb/E1BF48" } ], "pmid": "" }, { "name": "cell-cell junction maintenance", "id": "GO:0045217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045217", "evidence": [ { "database": "UniProtKB", "id": "E1BF48", "url": "https://www.uniprot.org/uniprotkb/E1BF48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BF48-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 440, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BF48-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BF48" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BF48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF48" }, { "id": "PF00021", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UPAR/Ly6", "eco_id": "ECO_0000259", "start_pos": 129, "end_pos": 206, "start_aa": "Ser", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BF93-1", "uniprot_ac": "E1BF93", "uniprot_id": "E1BF93_BOVIN", "mass": { "chemical_mass": 21789.0, "monoisotopic_mass": 21789.0 }, "refseq": { "ac": "NP_001289882", "name": "amelotin precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289882" }, "gene_names": [ { "name": "AMTN", "type": "recommended", "evidence": [ { "id": "E1BF93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF93" } ] }, { "name": "AMTN", "type": "synonym", "evidence": [ { "id": "NP_001289882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289882" } ] } ], "protein_names": [ { "name": "Amelotin", "type": "synonym", "evidence": [ { "id": "E1BF93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF93/entry#names_and_taxonomy" } ] }, { "name": "amelotin precursor", "type": "synonym", "evidence": [ { "id": "NP_001289882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289882" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BF93", "url": "https://www.uniprot.org/uniprotkb/E1BF93" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AMTN", "url": "https://www.uniprot.org/uniprotkb/E1BF93", "locus": { "chromosome": "6", "start_pos": 85917032, "end_pos": 85903765, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002928", "url": "https://www.ensembl.org/id/ENSBTAG00000002928" } ] } } ], "crossref": [ { "id": "E1BF93", "url": "https://alphafold.ebi.ac.uk/entry/E1BF93", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002928", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002928", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618393", "url": "https://www.ncbi.nlm.nih.gov/gene/618393", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618393", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618393", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PQMLPIF", "url": "https://omabrowser.org/oma/group/PQMLPIF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M408", "url": "https://www.orthodb.org/?gene=A0A3Q1M408", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BF93", "url": "https://www.orthodb.org/?gene=E1BF93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36858", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36858", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36858:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36858:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15757", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15757", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001289882", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289882", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M408", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M408", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M408-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M408-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF93", "url": "https://www.uniprot.org/uniprotkb/E1BF93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF93-1", "url": "https://www.uniprot.org/uniprotkb/E1BF93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAAILLFCLLGSTLSLPMQLNPALVLPPTKLVPDQATLLNPQQPNQVFSSLSLIPLTHMLTLGSNLQLLNPAAGMPSGTQTLPLALGGLKVQQQLQPQMLPVIVAHFGAQGTILSSEELQGTSQILTGLIFHPLFPGAILPTSQANPDAQNGILPAGQAGANPAAQGTPEDPFSTPSGTDDDFASTTPAGIQRGRPTTEETPTGSPKGIQ", "length": 211, "header": "tr|E1BF93-1|E1BF93_BOVIN Isoform 1 of Amelotin OS=Bos taurus OX=9913 GN=AMTN PE=4 SV=2 CANONICAL=E1BF93-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M408-1", "url": "https://www.uniprot.org/uniprotkb/E1BF93/entry#A0A3Q1M408-1", "sequence": { "sequence": "MKAAILLFCLLGSTLSLPMQLNPALVLPPTKLVPDQATLLNPQQPNQVFSSLSLIPLTHMLTLGSNLQLLNPAAGMPSGTQTLPLALGGLKVQQQLQPQMLPVIVAHFGAQQGTSQILTGLIFHPLFPGAILPTSQANPDAQNGILPAGQAGANPAAQGTPEDPFSTPSGTDDDFASTTPAGIQRGRPTTEETPTGSPKGIQ", "length": 202, "header": "tr|A0A3Q1M408-1|E1BF93_BOVIN Computationally mapped isoform of Amelotin OS=Bos taurus OX=9913 GN=AMTN PE=4 SV=1 CANONICAL=E1BF93-1" }, "locus": { "chromosome": "6", "start_pos": 85916982, "end_pos": 85903781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087300.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087300.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064919.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064919.1" } ] } }, { "isoform_ac": "E1BF93-1", "url": "https://www.uniprot.org/uniprotkb/E1BF93/entry#E1BF93-1", "sequence": { "sequence": "MKAAILLFCLLGSTLSLPMQLNPALVLPPTKLVPDQATLLNPQQPNQVFSSLSLIPLTHMLTLGSNLQLLNPAAGMPSGTQTLPLALGGLKVQQQLQPQMLPVIVAHFGAQGTILSSEELQGTSQILTGLIFHPLFPGAILPTSQANPDAQNGILPAGQAGANPAAQGTPEDPFSTPSGTDDDFASTTPAGIQRGRPTTEETPTGSPKGIQ", "length": 211, "header": "tr|E1BF93-1|E1BF93_BOVIN Isoform 1 of Amelotin OS=Bos taurus OX=9913 GN=AMTN PE=4 SV=2 CANONICAL=E1BF93-1" }, "locus": { "chromosome": "6", "start_pos": 85916982, "end_pos": 85903781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003804.5", "url": "https://www.ensembl.org/id/ENSBTAT00000003804.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003804.4", "url": "https://www.ensembl.org/id/ENSBTAP00000003804.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:618393", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618393", "resource": "KEGG Pathway" }, { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-BTA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3HS82-1", "protein_name": "Amelotin", "gene_name": "Amtn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTVVLLLCLLGSAQSLPRQLSPALGAPATKPTPGQVTPLTQQQPNQVFPSISLIPLTQLLTLGSDLPLFNPATMPHGTQTLPFTLGPLNGQQQLQPQMLPIIVAQLGAQGALLSSEELPLASQIFTGLLIHPLFPGAIQPSGQTGAKPDVQNGALPTRQAGASPANQATTPGHTTPAVTDDDDYEMSTPAGLQRATHTTEGTTMDPPNRTK", "length": 212 }, "evidence": [ { "id": "E1BF93", "url": "https://omabrowser.org/oma/group/E1BF93/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6UX39-1", "protein_name": "Amelotin", "gene_name": "AMTN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSTILLFCLLGSTRSLPQLKPALGLPPTKLAPDQGTLPNQQQSNQVFPSLSLIPLTQMLTLGPDLHLLNPAAGMTPGTQTHPLTLGGLNVQQQLHPHVLPIFVTQLGAQGTILSSEELPQIFTSLIIHSLFPGGILPTSQAGANPDVQDGSLPAGGAGVNPATQGTPAGRLPTPSGTDDDFAVTTPAGIQRSTHAIEEATTESANGIQ", "length": 209 }, "evidence": [ { "id": "E1BF93", "url": "https://omabrowser.org/oma/group/E1BF93/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D3J8-1", "protein_name": "Amelotin", "gene_name": "Amtn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTMILLLCLLGSAQSLPKQLNPASGVPATKPTPGQVTPLPQQQPNQVFPSISLIPLTQLLTLGSDLPLFNPAAGPHGAHTLPFTLGPLNGQQQLQPQMLPIIVAQLGAQGALLSSEELPLASQIFTGLLIHPLFPGAIPPSGQAGTKPDVQNGVLPTRQAGAKAVNQGTTPGHVTTPGVTDDDDYEMSTPAGLRRATHTTEGTTIDPPNRTQ", "length": 213 }, "evidence": [ { "id": "E1BF93", "url": "https://omabrowser.org/oma/group/E1BF93/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "odontogenesis of dentin-containing tooth", "id": "GO:0042475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042475", "evidence": [ { "database": "UniProtKB", "id": "E1BF93", "url": "https://www.uniprot.org/uniprotkb/E1BF93" } ], "pmid": "" }, { "name": "positive regulation of enamel mineralization", "id": "GO:0070175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070175", "evidence": [ { "database": "UniProtKB", "id": "E1BF93", "url": "https://www.uniprot.org/uniprotkb/E1BF93" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "E1BF93", "url": "https://www.uniprot.org/uniprotkb/E1BF93" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "E1BF93", "url": "https://www.uniprot.org/uniprotkb/E1BF93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BF93-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 211, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BF93-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BF93" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIS1-1", "uniprot_ac": "E1BIS1", "uniprot_id": "E1BIS1_BOVIN", "mass": { "chemical_mass": 69011.0, "monoisotopic_mass": 69011.0 }, "refseq": { "ac": "XP_005220664", "name": "suppressor of cytokine signaling 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220664" }, "gene_names": [ { "name": "SOCS7", "type": "recommended", "evidence": [ { "id": "E1BIS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" } ] }, { "name": "SOCS7", "type": "synonym", "evidence": [ { "id": "XP_005220664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220664" } ] } ], "protein_names": [ { "name": "Suppressor of cytokine signaling 7", "type": "recommended", "evidence": [ { "id": "E1BIS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS1/entry#names_and_taxonomy" } ] }, { "name": "suppressor of cytokine signaling 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005220664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220664" } ] } ], "function": [ { "annotation": "Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DAB1 and IRS1. Specifically recognizes and binds phosphorylated proteins via its SH2 domain, promoting their ubiquitination. The ECS(SOCS7) complex acts as a key regulator of reelin signaling by mediating ubiquitination and degradation of phosphorylated DAB1 in the cortical plate of the developing cerebral cortex, thereby regulating neuron positioning during cortex development. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Also inhibits prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.", "evidence": [ { "database": "UniProtKB", "id": "E1BIS1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1#function" }, { "database": "UniProtKB", "id": "ARBA00059017", "url": "https://www.uniprot.org/uniprotkb/ARBA00059017#function" }, { "database": "UniProtKB", "id": "A0A3Q1M426", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M426#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIS1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SOCS7", "url": "https://www.uniprot.org/uniprotkb/E1BIS1", "locus": { "chromosome": "19", "start_pos": 39036089, "end_pos": 39010987, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008535", "url": "https://www.ensembl.org/id/ENSBTAG00000008535" } ] } } ], "crossref": [ { "id": "E1BIS1", "url": "https://alphafold.ebi.ac.uk/entry/E1BIS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008535", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008535", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03741", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03741", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10388", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10388", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540586", "url": "https://www.ncbi.nlm.nih.gov/gene/540586", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SHTHIHH", "url": "https://omabrowser.org/oma/group/SHTHIHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M426", "url": "https://www.orthodb.org/?gene=A0A3Q1M426", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BIS1", "url": "https://www.orthodb.org/?gene=E1BIS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10155:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10155:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005220664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220664", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M426", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M426", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M426-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M426-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIS1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIS1-1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGAELRDGEAAAAAASYRVLSRLLGYGEAAPEPGPPPPPPGHGPAPPPFLARPGPRGSRPPQLMVFRNVGRPPEEEDAEAAQEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQTPGPELPPVPFPMQDLVPPGRLSRGEQPQQPPPPPPPPGPLRPLAGLSRKGSLKIRLSRLFRTKSCNGGSGGGDGAGKRPSGELVASAASLTDMGGSAGRELDAGRKPRLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVLEPST", "length": 642, "header": "tr|E1BIS1-1|E1BIS1_BOVIN Isoform 1 of Suppressor of cytokine signaling 7 OS=Bos taurus OX=9913 GN=SOCS7 PE=4 SV=2 CANONICAL=E1BIS1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M426-1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1/entry#A0A3Q1M426-1", "sequence": { "sequence": "MQGAELRDGEAAAAAASYRVLSRLLGYGEAAPEPGPPPPPPGHGPAPPPFLARPGPRGSRPPQLMVFRNVGRPPEEEDAEAAQEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQTPGPELPPVPFPMQDLVPPGRLSRGEQPQQPPPPPPPPGPLRPLAGLSRKGSLKIRLSRLFRTKSCNGGSGGGDGAGKRPSGELVASAASLTDMGGSAGRELDAGRKPRLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVLEPST", "length": 608, "header": "tr|A0A3Q1M426-1|E1BIS1_BOVIN Computationally mapped isoform of Suppressor of cytokine signaling 7 OS=Bos taurus OX=9913 GN=SOCS7 PE=4 SV=1 CANONICAL=E1BIS1-1" }, "locus": { "chromosome": "19", "start_pos": 39036056, "end_pos": 39011186, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068649.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068649.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062973.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062973.1" } ] } }, { "isoform_ac": "E1BIS1-1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1/entry#E1BIS1-1", "sequence": { "sequence": "MQGAELRDGEAAAAAASYRVLSRLLGYGEAAPEPGPPPPPPGHGPAPPPFLARPGPRGSRPPQLMVFRNVGRPPEEEDAEAAQEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQTPGPELPPVPFPMQDLVPPGRLSRGEQPQQPPPPPPPPGPLRPLAGLSRKGSLKIRLSRLFRTKSCNGGSGGGDGAGKRPSGELVASAASLTDMGGSAGRELDAGRKPRLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVLEPST", "length": 642, "header": "tr|E1BIS1-1|E1BIS1_BOVIN Isoform 1 of Suppressor of cytokine signaling 7 OS=Bos taurus OX=9913 GN=SOCS7 PE=4 SV=2 CANONICAL=E1BIS1-1" }, "locus": { "chromosome": "19", "start_pos": 39036056, "end_pos": 39011186, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011251.4", "url": "https://www.ensembl.org/id/ENSBTAT00000011251.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011251.2", "url": "https://www.ensembl.org/id/ENSBTAP00000011251.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 367, "start_aa": "Thr", "end_pos": 367, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr367", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 561, "start_aa": "Thr", "end_pos": 561, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr561", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K9S1-1", "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "Socs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGAELRDGEAAAAAASYRVLSRLLGYGEAAPEPGPPPPPPGHGPPPPPFLARPGSRGARPPQLMVFRNVGRPPEEEDAEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPVAGLEAQLAALGLGQPAGPGIKTAGGGCCPCPCPPQPPPPQPPPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGVGGRLLLQPPGPELPPVPFPLQDLVPPGRLSRGEQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGDLAASAASLTDMGGSAVRELDAGRKPRLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRASESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST", "length": 642 }, "evidence": [ { "id": "E1BIS1", "url": "https://omabrowser.org/oma/group/E1BIS1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZQS3-1", "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "SOCS7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQRAELRDGEAAAAASYRVLSRLLGYGAGPEAGAAGGPGSGAAVAGPPGPGGARLPLPVPAPGGAPRPPPQLMVFRNAAEGRPGEEEAAAGGGEGPAGGPELLCPRHRCALEPKAAAGGGWGPPGGLELQLAALGLRPPALGAKGPAACPCLGPPAAEETSDALLVLEALEPDEAESCSEEEPGSPGPADPQEPPRGAAAAAARRAVPGPGAAGGRKGSLRVRLSRLFRTKSCSGGSAPGDGGGGSRRGAELTASAHSLSDGGGARGRGQEEGRKHRLTRTQSAFSPVVFSPLFTGETVSLVDVDISQRGLSSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVGPMGSSLQSFPLPPPPPPHAPDAFPRVVPLRPTEPAPIQPAPHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPELPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISRQKQDAESST", "length": 592 }, "evidence": [ { "id": "E1BIS1", "url": "https://omabrowser.org/oma/group/E1BIS1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F6Q553-1", "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "SOCS7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQGAELRDGEAAAAAASYRVLSRLLGYGEAAPEPGPPPPPPGHGPAPPPFLARPGPRGSRPPQLMVFRNVGRPPEEEDAEAAPDPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQSAGPGVKTVSGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPMQDLVLPGRLSRGEQQQQQQQPPPPPPPPGPLRPLAGPSRKGSLKIRLSRLFRTKSCNGGSGGGDGAGKRPSGELAASAGSLTDMGGSAGRELDTGRKPRLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPTRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEIKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVLEPST", "length": 645 }, "evidence": [ { "id": "E1BIS1", "url": "https://omabrowser.org/oma/group/E1BIS1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O14512-1", "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "SOCS7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST", "length": 581 }, "evidence": [ { "id": "E1BIS1", "url": "https://omabrowser.org/oma/group/E1BIS1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VHQ2-1", "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "Socs7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVFRNVGRPPEEEDAEAAREPGPSELLCPRHRCALDPKALPPGLALERTWGPVAGLEAQLAALGLGQPAGPGIKTAGGGCCPCPCPPQPPPPQPPPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGVGGRLLLQPPGPELPPVPFPLQDLVPPGRLSRGEQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGDLAASAASLTDMGGSAVRELDTGRKPRLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRASESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST", "length": 579 }, "evidence": [ { "id": "E1BIS1", "url": "https://omabrowser.org/oma/group/E1BIS1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BIS1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BIS1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BIS1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BIS1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BIS1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "E1BIS1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "E1BIS1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "E1BIS1", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIS1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 642, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIS1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIS1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 460, "end_pos": 569, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BIS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS1" }, { "id": "PS50225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SOCS box", "eco_id": "ECO_0000259", "start_pos": 564, "end_pos": 614, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 367, 561 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BI86-1", "uniprot_ac": "E1BI86", "uniprot_id": "E1BI86_BOVIN", "mass": { "chemical_mass": 39750.0, "monoisotopic_mass": 39750.0 }, "refseq": {}, "gene_names": [ { "name": "FAM76B", "type": "recommended", "evidence": [ { "id": "E1BI86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI86" } ] } ], "protein_names": [ { "name": "Protein FAM76B", "type": "recommended", "evidence": [ { "id": "E1BI86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI86/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BI86", "url": "https://www.uniprot.org/uniprotkb/E1BI86" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM76B", "url": "https://www.uniprot.org/uniprotkb/E1BI86", "locus": { "chromosome": "15", "start_pos": 14509960, "end_pos": 14488841, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020748", "url": "https://www.ensembl.org/id/ENSBTAG00000020748" } ] } } ], "crossref": [ { "id": "E1BI86", "url": "https://alphafold.ebi.ac.uk/entry/E1BI86", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020748", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020748", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "519943", "url": "https://www.ncbi.nlm.nih.gov/gene/519943", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519943", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519943", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CACAYKR", "url": "https://omabrowser.org/oma/group/CACAYKR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M8T2", "url": "https://www.orthodb.org/?gene=A0A3Q1M8T2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BI86", "url": "https://www.orthodb.org/?gene=E1BI86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46176:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46176:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1M8T2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8T2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAS8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAS8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI86", "url": "https://www.uniprot.org/uniprotkb/E1BI86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI86-1", "url": "https://www.uniprot.org/uniprotkb/E1BI86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VEWDKIKPNSKLKTLHHFPRAKRRRELEFDPGTPLQECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHAKHHHHHHHHHHRHSSSHHKISNLSPEQEQGLWKQSHKSSAAIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP", "length": 346, "header": "tr|E1BI86-1|E1BI86_BOVIN Isoform 1 of Protein FAM76B OS=Bos taurus OX=9913 GN=FAM76B PE=3 SV=2 CANONICAL=E1BI86-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M8T2-1", "url": "https://www.uniprot.org/uniprotkb/E1BI86/entry#A0A3Q1M8T2-1", "sequence": { "sequence": "AKPQRNSPLRLPPPLSGPKRERLGRRHWECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHAKHHHHHHHHHHRHSSSHHKISNLSPEQEQGLWKQSHKSSAAIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP", "length": 338, "header": "tr|A0A3Q1M8T2-1|E1BI86_BOVIN Computationally mapped isoform of Protein FAM76B OS=Bos taurus OX=9913 GN=FAM76B PE=3 SV=2 CANONICAL=E1BI86-1" }, "locus": { "chromosome": "15", "start_pos": 14508671, "end_pos": 14489549, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078319.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078319.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064869.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064869.2" } ] } }, { "isoform_ac": "A0AAA9SAS8-1", "url": "https://www.uniprot.org/uniprotkb/E1BI86/entry#A0AAA9SAS8-1", "sequence": { "sequence": "MAASALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHAKHHHHHHHHHHRHSSSHHKISNLSPEQEQGLWKQSHKSSAAIQNETPKKKPKLESKPSNGDSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP", "length": 338, "header": "tr|A0AAA9SAS8-1|E1BI86_BOVIN Computationally mapped isoform of Protein FAM76B OS=Bos taurus OX=9913 GN=FAM76B PE=3 SV=2 CANONICAL=E1BI86-1" }, "locus": { "chromosome": "15", "start_pos": 14508671, "end_pos": 14489857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116297.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116297.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082450.2", "url": "https://www.ensembl.org/id/ENSBTAP00000082450.2" } ] } }, { "isoform_ac": "E1BI86-1", "url": "https://www.uniprot.org/uniprotkb/E1BI86/entry#E1BI86-1", "sequence": { "sequence": "VEWDKIKPNSKLKTLHHFPRAKRRRELEFDPGTPLQECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHAKHHHHHHHHHHRHSSSHHKISNLSPEQEQGLWKQSHKSSAAIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP", "length": 346, "header": "tr|E1BI86-1|E1BI86_BOVIN Isoform 1 of Protein FAM76B OS=Bos taurus OX=9913 GN=FAM76B PE=3 SV=2 CANONICAL=E1BI86-1" }, "locus": { "chromosome": "15", "start_pos": 14508671, "end_pos": 14489040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027650.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027650.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027650.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027650.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:519943", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519943", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GG35-1", "protein_name": "Protein FAM76B", "gene_name": "Fam76b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGAPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHSKHHHHHHHHHHRHSSGHHKVSSLSPEQEQGLWKQSHKSSAAIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRAKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSVLTSP", "length": 339 }, "evidence": [ { "id": "E1BI86", "url": "https://omabrowser.org/oma/group/E1BI86/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NYM6-1", "protein_name": "Protein FAM76B", "gene_name": "FAM76B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAAAPALYACTKCNQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHSKHHHHHHHHHRHSSSHHKISSLSPEQDQGLWKQSHKSSAAIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP", "length": 341 }, "evidence": [ { "id": "E1BI86", "url": "https://omabrowser.org/oma/group/E1BI86/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1STI7-1", "protein_name": "Protein FAM76B", "gene_name": "FAM76B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAASALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKGLGSSHSNSSSSSLTEKDQHHSKHHHHHHHHHHRHGSSHHKISNLSPEQEQGLWKQSHKSSATIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP", "length": 339 }, "evidence": [ { "id": "E1BI86", "url": "https://omabrowser.org/oma/group/E1BI86/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5HYJ3-1", "protein_name": "Protein FAM76B", "gene_name": "FAM76B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHPKHHHHHHHHHHRHSSSHHKISNLSPEEEQGLWKQSHKSSATIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP", "length": 339 }, "evidence": [ { "id": "E1BI86", "url": "https://omabrowser.org/oma/group/E1BI86/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PBM7-1", "protein_name": "Protein FAM76B", "gene_name": "fam76b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATSALYACTKCNQRFPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKDEGRRKVDGKLLCWLCTLSYRRVLQKTKEQRKGLGSSHSNSSSLSEKEHQRHHHHHQHHRHGSSHHKISGNLSPEQDQGLWKQSIQKETPKKKPKLETKPSNGDSSSITQSMDSGGTDNFILISQLKEEVMSLKRMLQQRDQTILEKDRKLTELKADFQYQESNMRVKMNNMEKAHKEAMEQQQAKNRELLKQVAALSKGKKFDRSGSSLLLP", "length": 328 }, "evidence": [ { "id": "E1BI86", "url": "https://omabrowser.org/oma/group/E1BI86/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80XP8-1", "protein_name": "Protein FAM76B", "gene_name": "Fam76b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGAPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHSKHHHHHHHHHHRHSSGHHKVSSLSPEQEQGLWKQSHKSSAAIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSVLTSP", "length": 339 }, "evidence": [ { "id": "E1BI86", "url": "https://omabrowser.org/oma/group/E1BI86/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VSW7-1", "protein_name": "Protein FAM76A", "gene_name": "anon-WO0172774.118", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSGKVLFACSKCFSRHLYEELSSGQQLCKGCRGSTSVGKCTYCRSEFQPATKSQSACKKCEHYLGKYGKPSACECCKIVAAFGGSKCMRCASYEAKYGPPVQCDECKLRSAFDRRDENKKVNGKLLCWLCACAYKRALLKAQQEGRIPMSKKRPHEKTSSSHRDSAAAKKPSRNELGKSGSGANNSGVNAVSGAGLDLPDKISRGNGGNGTIAAPAAITVDTNSSDHVVAITYLKERIASLEKRLNQKDKELLEKDKQLTELKGKNFEKENDMRNRLKEVERLHDMKVDNLNRKIASVLKELAVLKKSSNKKTAAISKAEKEIIKRENLSPKEEILATTGPEKPTKASSEPADLDKDEKSRDRDEERSEQGDRASVRSRSASSSPTPSSN", "length": 390 }, "evidence": [ { "id": "E1BI86", "url": "https://omabrowser.org/oma/group/E1BI86/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BI86", "url": "https://www.uniprot.org/uniprotkb/E1BI86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "E1BI86", "url": "https://www.uniprot.org/uniprotkb/E1BI86" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "E1BI86", "url": "https://www.uniprot.org/uniprotkb/E1BI86" } ], "pmid": "" }, { "name": "negative regulation of macrophage activation", "id": "GO:0043031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043031", "evidence": [ { "database": "UniProtKB", "id": "E1BI86", "url": "https://www.uniprot.org/uniprotkb/E1BI86" } ], "pmid": "" }, { "name": "negative regulation of protein export from nucleus", "id": "GO:0046826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046826", "evidence": [ { "database": "UniProtKB", "id": "E1BI86", "url": "https://www.uniprot.org/uniprotkb/E1BI86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BI86-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 346, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BI86-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BI86" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 242, "end_pos": 244 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIK9-1", "uniprot_ac": "E1BIK9", "uniprot_id": "E1BIK9_BOVIN", "mass": { "chemical_mass": 95221.0, "monoisotopic_mass": 95221.0 }, "refseq": { "ac": "XP_003586050", "name": "striatin-interacting protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586050" }, "gene_names": [ { "name": "STRIP2", "type": "recommended", "evidence": [ { "id": "E1BIK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIK9" } ] }, { "name": "STRIP2", "type": "synonym", "evidence": [ { "id": "XP_003586050", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586050" } ] } ], "protein_names": [ { "name": "Striatin interacting protein 2", "type": "synonym", "evidence": [ { "id": "E1BIK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIK9/entry#names_and_taxonomy" } ] }, { "name": "striatin-interacting protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003586050", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586050" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIK9", "url": "https://www.uniprot.org/uniprotkb/E1BIK9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "STRIP2", "url": "https://www.uniprot.org/uniprotkb/E1BIK9", "locus": { "chromosome": "4", "start_pos": 93386791, "end_pos": 93338797, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007206", "url": "https://www.ensembl.org/id/ENSBTAG00000007206" } ] } } ], "crossref": [ { "id": "E1BIK9", "url": "https://alphafold.ebi.ac.uk/entry/E1BIK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007206", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007206", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "529423", "url": "https://www.ncbi.nlm.nih.gov/gene/529423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012486", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012486", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:529423", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETDSYGW", "url": "https://omabrowser.org/oma/group/ETDSYGW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MA25", "url": "https://www.orthodb.org/?gene=A0A3Q1MA25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BIK9", "url": "https://www.orthodb.org/?gene=E1BIK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13239:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13239:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11882", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11882", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003586050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586050", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MA25", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MA25-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0X4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0X4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIK9", "url": "https://www.uniprot.org/uniprotkb/E1BIK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIK9-1", "url": "https://www.uniprot.org/uniprotkb/E1BIK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDPAAPGAGNPPTNGNGNGGGKGKPAAPKGREAFRSQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTENPEFTTNRRCFEEDFKTQVQGEEWLELEEDAQKAYVMGLLDRLEVVSRERRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYQMGTFSAFLELLHMEIDNSQACSSALRKPAISIADSTELRVLLSVLYLMVENIRLERETDSCGWRTARETFRTELSFSTHNQEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKVQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESASDGERTLDGELDLLEQDPLVPPPPSQAPLSAERVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYVSIADVQIKNEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNGISVLDYPCCTIQDLPELTTESLEAGDNNQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDRPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "length": 834, "header": "tr|E1BIK9-1|E1BIK9_BOVIN Isoform 1 of Striatin interacting protein 2 OS=Bos taurus OX=9913 GN=STRIP2 PE=3 SV=1 CANONICAL=E1BIK9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MA25-1", "url": "https://www.uniprot.org/uniprotkb/E1BIK9/entry#A0A3Q1MA25-1", "sequence": { "sequence": "MEDPAAPGAGNPPTNGNGNGGGKGKPAAPKGREAFRSQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTENPEFTTNRRCFEEDFKTQVQGEEWLELEEDAQKAYVMGLLDRLEVVSRERRLKVARAVLYLAQATARPVAVLFGSQPSPLLTAQNSGFSTHNQEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKVQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESASDGERTLDGELDLLEQDPLVPPPPSQAPLSAERVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYVSIADVQIKNEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNGISVLDYPCCTIQDLPELTTESLEAGDNNQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDRPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "length": 758, "header": "tr|A0A3Q1MA25-1|E1BIK9_BOVIN Computationally mapped isoform of Striatin interacting protein 2 OS=Bos taurus OX=9913 GN=STRIP2 PE=3 SV=2 CANONICAL=E1BIK9-1" }, "locus": { "chromosome": "4", "start_pos": 93385787, "end_pos": 93338966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071907.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071907.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065359.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065359.2" } ] } }, { "isoform_ac": "A0ABI0P0X4-1", "url": "https://www.uniprot.org/uniprotkb/E1BIK9/entry#A0ABI0P0X4-1", "sequence": { "sequence": "MEDPAAPGAGNPPTNGNGNGGGKGKPAAPKGREAFRSQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTENPEFTTNRRCFEEDFKTQVQGEEWLELEEDAQKAYVMGLLDRLEVVSRERRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYQMGTFSAFLELLHMEIDNSQACSSALRKPAISIADSTELRVLLSVLYLMVENIRLERETDSCGWRTARETFRTELSFSTHNQEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKVQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESASDGERTLDGELDLLEQDPLVPPPPSQAPLSAERVAFPKGLPWAPKVRDTDTLVGLPRPIHESVKTLKQHKYVSIADVQIKNEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNGISVLDYPCCTIQDLPELTTESLEAGDNNQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDRPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "length": 812, "header": "tr|A0ABI0P0X4-1|A0ABI0P0X4_BOVIN Computationally mapped isoform of Striatin interacting protein 2 OS=Bos taurus OX=9913 GN=STRIP2 PE=3 SV=1 CANONICAL=E1BIK9-1" }, "locus": { "chromosome": "4", "start_pos": 93385787, "end_pos": 93338966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139279.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139279.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104999.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104999.1" } ] } }, { "isoform_ac": "E1BIK9-1", "url": "https://www.uniprot.org/uniprotkb/E1BIK9/entry#E1BIK9-1", "sequence": { "sequence": "MEDPAAPGAGNPPTNGNGNGGGKGKPAAPKGREAFRSQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTENPEFTTNRRCFEEDFKTQVQGEEWLELEEDAQKAYVMGLLDRLEVVSRERRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYQMGTFSAFLELLHMEIDNSQACSSALRKPAISIADSTELRVLLSVLYLMVENIRLERETDSCGWRTARETFRTELSFSTHNQEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKVQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESASDGERTLDGELDLLEQDPLVPPPPSQAPLSAERVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYVSIADVQIKNEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNGISVLDYPCCTIQDLPELTTESLEAGDNNQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDRPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "length": 834, "header": "tr|E1BIK9-1|E1BIK9_BOVIN Isoform 1 of Striatin interacting protein 2 OS=Bos taurus OX=9913 GN=STRIP2 PE=3 SV=1 CANONICAL=E1BIK9-1" }, "locus": { "chromosome": "4", "start_pos": 93385787, "end_pos": 93338966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009480.6", "url": "https://www.ensembl.org/id/ENSBTAT00000009480.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009480.3", "url": "https://www.ensembl.org/id/ENSBTAP00000009480.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:529423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529423", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G7M4-1", "protein_name": "Striatin interacting protein 2", "gene_name": "Strip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDPAAPGPSGSPANDNGNGNGNGNGNGNGGKGKPAVPKGREAFRNQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTESLEFTTNRKCFEEDFKTQVQDTKEWLELEEDAQKTYVMGLLDRLEVVSREQRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYRMGTFSAFLELLHMEIDNSQASSSALRKPAVSIADSTELRVLLSVMYLMVENIRLEREIDPCGWRTARETFRTELSFSTHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKIQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESASDGERTLDGELDLLEQDPLVPPPPSQTPLSADRVSFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIKNEEELEKCPMSLGEEVIPETPSEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPATVLQSMKLGIDVNRHKEIIVKSISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAGDNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDKPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "length": 844 }, "evidence": [ { "id": "E1BIK9", "url": "https://omabrowser.org/oma/group/E1BIK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PI62-1", "protein_name": "Striatin-interacting protein 1 homolog isoform X1", "gene_name": "strip2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQQTDDMEVPLIHDSNSNTHTCLPQERDGFHQQKDSEGSMESPNLEFEYGDTDSFTAELSELYSYTEEPEFSLNRDYFEEDFKNHVKGRRWMELSVEEQRAYVMRLLDALEVTDRDKRLKVARAILYLAQGVFDECDTETDVLYWSRHNVFLLYDMGIFTALLELLSMEIDNNQACSSAVRKPAISLADSTELRVLLSIMYLMVETIRVEMESDSPERKAAREAFKMELGSPLYNGEPFALLLFTMVTKFCSMNAPHFPMKKVLLLLWKTILFTLGGFEELQEMKVRMRDHLNLPPLPEDSIKVVRNMRAASPPASAMELIEQQQQQKRGRRSRRSAFVDSLEGDSPYAKKQPLVKQDSLDTYNERDPFKNDDARDEEDDPEDVDSGIEGEVDPLDRDVIIQPPPPPPPLRPPTERMSFPKGLPWAPKVREKDIEHFLETSRNKFIGFTLGNDIDTLVGLPRPIHESVKTLKLHKYVSIAEVQIKREDELQQCPMTMGEEEVEETPTEILYLGMLPSLSQYVIALLKLLLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKAISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNIMSYISAKNSICALDFPHCAVHEMPELTAESLEAGDSNQFCWRNLFSCINLLRILNKITKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDIDARPWDFQAEECALRESIEKFNTRRYDKNQNSEFAPVDNCLQSVLGQRVDLPEDFHYSYEMWLEREVFSQPIQWEGLLQAQ", "length": 839 }, "evidence": [ { "id": "E1BIK9", "url": "https://omabrowser.org/oma/group/E1BIK9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C9H6-1", "protein_name": "Striatin-interacting proteins 2", "gene_name": "Strip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDPAAPGPAGSPANDNGNGNGNGNGNGNGGKGKPAVPKGRETFRNQRRESEGSVDCPTLEFEYGDSDGHAAELSELYSYTENLEFTTNRKCFEEDFRTQVQDTKEWLELEEDAQKTYVMGLLDRLEVVSREKRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYQMGTFSAFLELLHMEIDNSQASSSALRKPAVSIADSTELRVLLSVMYLMVENIRLEREIDPCGWRTARETFRTELSFSTHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKIQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESAADGERTLDGELDLLEQDPLVPPPPSQTPLSTDRVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADIQIKNEEELEKCPLSLGEEVVPETPSEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPVTVLQSMKLGIDVNRHKEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAGDNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDKPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "length": 844 }, "evidence": [ { "id": "E1BIK9", "url": "https://omabrowser.org/oma/group/E1BIK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULQ0-1", "protein_name": "Striatin-interacting protein 2", "gene_name": "STRIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDPAAPGTGGPPANGNGNGGGKGKQAAPKGREAFRSQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTENLEFTNNRRCFEEDFKTQVQGKEWLELEEDAQKAYIMGLLDRLEVVSRERRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYQMGTFSTFLELLHMEIDNSQACSSALRKPAVSIADSTELRVLLSVMYLMVENIRLERETDPCGWRTARETFRTELSFSMHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQTLKVQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESAGDGERTLDGELDLLEQDPLVPPPPSQAPLSAERVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIKNEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKSISTLLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAGDNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKLQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDRPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "length": 834 }, "evidence": [ { "id": "E1BIK9", "url": "https://omabrowser.org/oma/group/E1BIK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BIK9", "url": "https://www.uniprot.org/uniprotkb/E1BIK9" } ], "pmid": "" }, { "name": "FAR/SIN/STRIPAK complex", "id": "GO:0090443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090443", "evidence": [ { "database": "UniProtKB", "id": "E1BIK9", "url": "https://www.uniprot.org/uniprotkb/E1BIK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BIK9", "url": "https://www.uniprot.org/uniprotkb/E1BIK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "E1BIK9", "url": "https://www.uniprot.org/uniprotkb/E1BIK9" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "E1BIK9", "url": "https://www.uniprot.org/uniprotkb/E1BIK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIK9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 834, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIK9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIK9" } ], "lectin_list": [], "domain_list": [ { 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CANONICAL=E1BJ33-1" }, "locus": { "chromosome": "29", "start_pos": 42811740, "end_pos": 42795815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025016.8", "url": "https://www.ensembl.org/id/ENSBTAT00000025016.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025016.7", "url": "https://www.ensembl.org/id/ENSBTAP00000025016.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-561048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-561048", "resource": "Reactome", "description": "Organic anion transport by SLC22 transporters" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BJ33", "url": "https://www.uniprot.org/uniprotkb/E1BJ33" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "E1BJ33", "url": "https://www.uniprot.org/uniprotkb/E1BJ33" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "E1BJ33", "url": "https://www.uniprot.org/uniprotkb/E1BJ33" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "E1BJ33", "url": "https://www.uniprot.org/uniprotkb/E1BJ33" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "E1BJ33", "url": "https://www.uniprot.org/uniprotkb/E1BJ33" } ], "pmid": "" } ] }, { "name": 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"start_pos": 1, "end_pos": 548, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJ33-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJ33" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJ33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ33" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 101, "end_pos": 514, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 63, "end_pos": 65 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIT3-1", "uniprot_ac": "E1BIT3", "uniprot_id": "E1BIT3_BOVIN", "mass": { "chemical_mass": 120658.0, "monoisotopic_mass": 120658.0 }, "refseq": {}, "gene_names": [ { "name": "LRIG2", "type": "recommended", "evidence": [ { "id": "E1BIT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIT3" } ] } ], "protein_names": [ { "name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "type": "recommended", "evidence": [ { "id": "E1BIT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIT3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIT3", "url": "https://www.uniprot.org/uniprotkb/E1BIT3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LRIG2", "url": "https://www.uniprot.org/uniprotkb/E1BIT3", "locus": { "chromosome": "3", "start_pos": 30209449, "end_pos": 30272471, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008525", "url": "https://www.ensembl.org/id/ENSBTAG00000008525" } ] } } ], "crossref": [ { "id": "E1BIT3", "url": "https://alphafold.ebi.ac.uk/entry/E1BIT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008525", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008525", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05763", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05763", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "535493", "url": "https://www.ncbi.nlm.nih.gov/gene/535493", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QVTMNHN", "url": "https://omabrowser.org/oma/group/QVTMNHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MFF7", "url": "https://www.orthodb.org/?gene=A0A3Q1MFF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MQT1", "url": "https://www.orthodb.org/?gene=A0A3Q1MQT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BIT3", "url": "https://www.orthodb.org/?gene=E1BIT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MFF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MFF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQT1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIT3", "url": "https://www.uniprot.org/uniprotkb/E1BIT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIT3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPAPQGVREEPLLECGSRLLSRLLFLAQAVVLLLPAARAGLCPVPCSCRIPLLDCSRRKLPAPSWRALSTSLPPDAVSLDLSHNRLSNWNISLESQTLQEVLLRLLYSRLKTRKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAEVFQFYPALETLDLSSNQISEIKTSSFPRMQLKYLNLSNNRITVLEAGCFDNLSSSLLVVKLNRNRISMIPPKIFKLPHLQFLELKRNRIKVVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLDNMEELELEHNNLTEVNKGWLYGLRMLQQLYVSQNAVERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLNLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSVTKKAFIGLESLEHLDLNNNAIMSIQENAFSQTRLKELILNTNSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDLLKPQIRTHPETTVALRGVNVTLRCTAVSSSDSPMSALWRKDSEVLYDADIENFVRYQQQAGEALEYTSVLHLFNVNFTDEGKYQCIITNHFGSNYSHKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLIVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLDDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYLHKGTDGGAGTRVICSDCYDNANIYSRTREYCPYTYITEEDVLDQTLSSLMVQMPKETYLAHPPQDATTLESLVSSAERERCAFPTNHERMNEKKPSSTRMSNETLQRPLWNVSREPGMPHPPFPQQSVLESSQLHQNEGLAESDPDCSTSPMPCHRLHDHTFDFSRTRNVHNGSEGT", "length": 1077, "header": "tr|E1BIT3-1|E1BIT3_BOVIN Isoform 1 of Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Bos taurus OX=9913 GN=LRIG2 PE=4 SV=4 CANONICAL=E1BIT3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MFF7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIT3/entry#A0A3Q1MFF7-1", "sequence": { "sequence": "MAPAPQGVREEPLLECGSRLLSRLLFLAQAVVLLLPAARAGLCPVPCSCRIPLLDCSRRKLPAPSWRALSTSLPPDAVSLDLSHNRLSNWNISLESQTLQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAEVFQFYPALETLDLSSNQISEIKTSSFPRMQLKYLNLSNNRITVLEAGCFDNLSSSLLVVKLNRNRISMIPPKIFKLPHLQFLELKRNRIKVVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLDNMEELELEHNNLTEVNKGWLYGLRMLQQLYVSQNAVERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLNLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSVTKKAFIGLESLEHLDLNNNAIMSIQENAFSQTRLKELILNTNSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDLLKPQIRTHPETTVALRGVNVTLRCTAVSSSDSPMSALWRKDSEVLYDADIENFVRYQQQAGEALEYTSVLHLFNVNFTDEGKYQCIITNHFGSNYSHKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLIVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLDDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYLHKGTDGGAGTRVICSDCYDNANIYSRTREYCPYTYITEEDVLDQTLSSLMVQMPKETYLAHPPQDATTLESLVSSAERERCAFPTNHERMNEKKPSSTRMSNGKGHGVVCCFETLQRPLWNVSREPGMPHPPFPQQSVLESSQLHQNEGLAESDPDCSTSPMPCHRLHDHTFDFSRTRNVHNGSEGT", "length": 1075, "header": "tr|A0A3Q1MFF7-1|E1BIT3_BOVIN Computationally mapped isoform of Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Bos taurus OX=9913 GN=LRIG2 PE=4 SV=2 CANONICAL=E1BIT3-1" }, "locus": { "chromosome": "3", "start_pos": 30272272, "end_pos": 30210908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071713.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071713.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069258.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069258.2" } ] } }, { "isoform_ac": "A0A3Q1MQT1-1", "url": "https://www.uniprot.org/uniprotkb/E1BIT3/entry#A0A3Q1MQT1-1", "sequence": { "sequence": "MAPAPQGVREEPLLECGSRLLSRLLFLAQAVVLLLPAARAGLCPVPCSCRIPLLDCSRRKLPAPSWRALSTSLPPDAVSLDLSHNRLSNWNISLESQTLQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAEVFQFYPALETLDLSSNQISEIKTSSFPRMQLKYLNLSNNRITVLEAGCFDNLSSSLLVVKLNRNRISMIPPKIFKLPHLQFLELKRNRIKVVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLDNMEELELEHNNLTEVNKGWLYGLRMLQQLYVSQNAVERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLNLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSVTKKAFIGLESLEHLDLNNNAIMSIQENAFSQTRLKELILNTNSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDLLKPQIRTHPETTVALRGVNVTLRCTAVSSSDSPMSALWRKDSEVLYDADIENFVRYQQQAGEALEYTSVLHLFNVNFTDEGKYQCIITNHFGSNYSHKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLIVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLDDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYLHKGTDGGAGTRVICSDCYDNANIYSRTREYCPYTYITEEDVLDQTLSSLMVQMPKETYLAHPPQDATTLESLVSSAERERCAFPTNHERMNEKKPSSTRMSNETLQRPLWNVSREPGQEITLEAPEKCAWDSAVILNV", "length": 1026, "header": "tr|A0A3Q1MQT1-1|E1BIT3_BOVIN Computationally mapped isoform of Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Bos taurus OX=9913 GN=LRIG2 PE=4 SV=1 CANONICAL=E1BIT3-1" }, "locus": { "chromosome": "3", "start_pos": 30272272, "end_pos": 30210453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086977.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086977.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056762.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056762.1" } ] } }, { "isoform_ac": "E1BIT3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIT3/entry#E1BIT3-1", "sequence": { "sequence": "MAPAPQGVREEPLLECGSRLLSRLLFLAQAVVLLLPAARAGLCPVPCSCRIPLLDCSRRKLPAPSWRALSTSLPPDAVSLDLSHNRLSNWNISLESQTLQEVLLRLLYSRLKTRKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAEVFQFYPALETLDLSSNQISEIKTSSFPRMQLKYLNLSNNRITVLEAGCFDNLSSSLLVVKLNRNRISMIPPKIFKLPHLQFLELKRNRIKVVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLDNMEELELEHNNLTEVNKGWLYGLRMLQQLYVSQNAVERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLNLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSVTKKAFIGLESLEHLDLNNNAIMSIQENAFSQTRLKELILNTNSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDLLKPQIRTHPETTVALRGVNVTLRCTAVSSSDSPMSALWRKDSEVLYDADIENFVRYQQQAGEALEYTSVLHLFNVNFTDEGKYQCIITNHFGSNYSHKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLIVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLDDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYLHKGTDGGAGTRVICSDCYDNANIYSRTREYCPYTYITEEDVLDQTLSSLMVQMPKETYLAHPPQDATTLESLVSSAERERCAFPTNHERMNEKKPSSTRMSNETLQRPLWNVSREPGMPHPPFPQQSVLESSQLHQNEGLAESDPDCSTSPMPCHRLHDHTFDFSRTRNVHNGSEGT", "length": 1077, "header": "tr|E1BIT3-1|E1BIT3_BOVIN Isoform 1 of Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Bos taurus OX=9913 GN=LRIG2 PE=4 SV=4 CANONICAL=E1BIT3-1" }, "locus": { "chromosome": "3", "start_pos": 30272272, "end_pos": 30210908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011238.6", "url": "https://www.ensembl.org/id/ENSBTAT00000011238.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011238.6", "url": "https://www.ensembl.org/id/ENSBTAP00000011238.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R228-1", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "gene_name": "LRIG2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASAPQGVREEQLLECGTGLFSRLLFLAQAVLLLLPAARASLCPAPCSCRIPLLDCSRRKLPAPSWRALSSSLPPDTASLDLSHNRLSNWNISLESQTLQEVKMNYNELTEIPYFGESTSNITLLSLVHNIIPEINAEVFQFYPALENLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITILEAGCFDNLSSSLLVVKLNRNRISMIPPKIFKLPHLQFLELKRNRIKVVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLDNMEELELEHNNLTEVNKGWLYGLRMLQQLYVSQNAVERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLNLRNNEISWAIEDASEAFSGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAITSIQENAFSQTRLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPETTVALRGMNVTLTCTAVSSSDSAMSAVWRKDSEILYDADIENFVRYQQQAGEALEYTSVLHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSSNCDSSQGSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYLHKGADGGTGTRVICSDCYDNANIYSRTREYCPYTYVAEEDVLEQTLSSLMVQMPKETYLAHPPQEATTLESLVSSADRGMSAFPSNHERINEKKLPSTQMSSETLQRPLWNISKDLGMPRAPFSQQPALESPQLHQNEGLAETDPDCSASPMPSRRLLDHAFDFSRTRNIQDGSEGT", "length": 1065 }, "evidence": [ { "id": "E1BIT3", "url": "https://omabrowser.org/oma/group/E1BIT3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZQV2-1", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "gene_name": "Lrig2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAPRGVWEQRRLGCRLGPLAPLLMLAQALLLLPAAGAGLCPAPCSCRLPLLDCSRRKLPALSWRALSGPLSPDISSLDLSHNRLSNWNISLESETLQEVKMNYNELTEIPYFGEPTPNITQLSLVHNLIPEINAEAFQLYSALESLDLSSNIISEIKTSSFPRMSLKYLNLSNNRITTLEAGCFDNLSGSLLVVKLNRNRISMIPPKVFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTGVHKGWLYGLRMLQQLYVSQNAIEKISPDAWEFCQRLSALDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEVFSGLKSLTKLILQGNRIKSVTQKAFVGLESLEYLDLNNNAIMSIQENAFSQTHLKELVLNTSSLLCDCHLKWLLQWLVDNNFHHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPENTVALRGVNVTLMCTAVSSSDSPMSTLWRKDSEILYDVDIENFVRYRQQDGEALEYTSVLRLFSVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPTPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCLMSNTLGTERGHIYLNVISSPNCDSSQNSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKDEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPASGYTHKGTDGGTGTRVICSDCYDNANIYSRTREYCPYTYIAEEDALDQALSSLMVQMPKETFLSHPPQDAANLESLMPPTERELSAFPTNHERTSENLPFSQRSSEIFQRPLWNMNRDLGLLPFPQQPVLESPQLAERDPNCSSPVSCHRLHDHAFDFSRTRNIQDGTEGT", "length": 1054 }, "evidence": [ { "id": "E1BIT3", "url": "https://omabrowser.org/oma/group/E1BIT3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O94898-1", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "gene_name": "LRIG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPAPLGVPEEQLLGCRSRVLSRLLFIAQTALLLLPAAGAGLCPAPCSCRIPLLDCSRRKLPAPSWRALSGLLPPDTAILDFSHNRLSNWNISLESQTLQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYIHKGTDGGTGTRVICSDCYDNANIYSRTREYCPYTYIAEEDVLDQTLSSLMVQMPKETYLVHPPQDTTALESLIPSANREPSAFPTNHERISEKKLPSTQMSGETLQRPVWNINRELGLPHPPFSQQPVHESPQLHQNEGLAGREPDCSASSMSCHRLQDHAFDFSRTRNIQDGSEGT", "length": 1065 }, "evidence": [ { "id": "E1BIT3", "url": "https://omabrowser.org/oma/group/E1BIT3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q52KR2-1", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "gene_name": "Lrig2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAPRGIWEQRRLGCGLGPLARLLILAQALRLLPAARAGLCPAPCACRLPLLDCSRRKLPAPSWRALSGPLPSDISSLDLSHNRLSNWNNTLESQTLQEVKMNYNELTEIPYFGEPTPNITLLSLVHNLIPEINAEAFELYSALESLDLSSNIISEIKTSSFPRMSLKYLNLSNNRISTLEAGCFDNLSDSLLVVKLNRNRISMIPPKVFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTGVNKGWLYGLRMLQQLYMSQNAIEKISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNDISWAIEDASEAFSGLKSLTKLILQGNRIKSVTQKAFIGLESLEYLDLNNNAIMSIQENAFSQTHLKGLVLNTSSLLCDCHLKWLLQWLVDNNFHHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPESTIALRGVNVTLTCTAVSSSDSPMSTIWRKDSEILYDVDIENFVRYRQQDGEALEYTSVLRLFSVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPTPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCLMSNTLGTERGHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYTHRGTDGGAGTRVICSDCYDNANIYSRTREYCPYTYIAEEDVLDQALSSLMVQMPKETFLSHPPQDAANLESLIPSAEREPAAFPTNHERMTENLPFSQRSSEIFQRPLWNMNRELGLLPFSQQPVLESPELTERDPNCSSPVTCRRLHDHAFDFSRTRIIQDGTEGT", "length": 1054 }, "evidence": [ { "id": "E1BIT3", "url": "https://omabrowser.org/oma/group/E1BIT3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BIT3", "url": "https://www.uniprot.org/uniprotkb/E1BIT3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BIT3", "url": "https://www.uniprot.org/uniprotkb/E1BIT3" } ], "pmid": "" }, { "name": "intracellular vesicle", "id": "GO:0097708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097708", "evidence": [ { "database": "UniProtKB", "id": "E1BIT3", "url": "https://www.uniprot.org/uniprotkb/E1BIT3" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "E1BIT3", "url": "https://www.uniprot.org/uniprotkb/E1BIT3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "E1BIT3", "url": "https://www.uniprot.org/uniprotkb/E1BIT3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "E1BIT3", "url": "https://www.uniprot.org/uniprotkb/E1BIT3" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "E1BIT3", "url": "https://www.uniprot.org/uniprotkb/E1BIT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1002, "end_pos": 1004, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1011, "end_pos": 1013, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1072, "end_pos": 1074, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 699, "end_pos": 701, "annotation": "n_glycosylation_sequon" }, { "start_pos": 740, "end_pos": 742, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIT3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1077, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIT3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIT3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIT3" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 510, "end_pos": 609, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1002, "end_pos": 1004 }, { "start_pos": 1011, "end_pos": 1013 }, { "start_pos": 1072, "end_pos": 1074 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 526, "end_pos": 528 }, { "start_pos": 583, "end_pos": 585 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 699, "end_pos": 701 }, { "start_pos": 740, "end_pos": 742 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJA0-1", "uniprot_ac": "E1BJA0", "uniprot_id": "E1BJA0_BOVIN", "mass": { "chemical_mass": 26650.0, "monoisotopic_mass": 26650.0 }, "refseq": { "ac": "NP_001179922", "name": "ras-related protein Rab-33A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179922" }, "gene_names": [ { "name": "RAB33A", "type": "recommended", "evidence": [ { "id": "E1BJA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ] }, { "name": "RAB33A", "type": "synonym", "evidence": [ { "id": "NP_001179922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179922" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "E1BJA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJA0/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "E1BJA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJA0/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-33A", "type": "synonym", "evidence": [ { "id": "NP_001179922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179922" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJA0", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RAB33A", "url": "https://www.uniprot.org/uniprotkb/E1BJA0", "locus": { "chromosome": "X", "start_pos": 14141236, "end_pos": 14130833, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000034712", "url": "https://www.ensembl.org/id/ENSBTAG00000034712" } ] } } ], "crossref": [ { "id": "E1BJA0", "url": "https://alphafold.ebi.ac.uk/entry/E1BJA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000034712", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000034712", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04115", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04115", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "510101", "url": "https://www.ncbi.nlm.nih.gov/gene/510101", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510101", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510101", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPQETNS", "url": "https://omabrowser.org/oma/group/FPQETNS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJA0", "url": "https://www.orthodb.org/?gene=E1BJA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47978", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47978", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8873719", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8873719", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179922", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179922", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MFH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MFH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJA0", "url": "https://www.uniprot.org/uniprotkb/E1BJA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJA0-1", "url": "https://www.uniprot.org/uniprotkb/E1BJA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQPILGHGNLQPTSAAGLASLELDSSLDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDAERQQGKVQKLEFPQEANSKTSCPC", "length": 237, "header": "tr|E1BJA0-1|E1BJA0_BOVIN Isoform 1 of small monomeric GTPase OS=Bos taurus OX=9913 GN=RAB33A PE=3 SV=1 CANONICAL=E1BJA0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MFH6-1", "url": "https://www.uniprot.org/uniprotkb/E1BJA0/entry#A0A3Q1MFH6-1", "sequence": { "sequence": "MQRRGGGRGGLGSAVGSQARGHRRKEKPTSAAGLASLELDSSLDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDAERQQGKVQKLEFPQEANSKTSCPC", "length": 252, "header": "tr|A0A3Q1MFH6-1|E1BJA0_BOVIN Computationally mapped isoform of small monomeric GTPase OS=Bos taurus OX=9913 GN=RAB33A PE=3 SV=1 CANONICAL=E1BJA0-1" }, "locus": { "chromosome": "X", "start_pos": 14141101, "end_pos": 14131108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083670.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083670.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067701.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067701.2" } ] } }, { "isoform_ac": "E1BJA0-1", "url": "https://www.uniprot.org/uniprotkb/E1BJA0/entry#E1BJA0-1", "sequence": { "sequence": "MAQPILGHGNLQPTSAAGLASLELDSSLDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDAERQQGKVQKLEFPQEANSKTSCPC", "length": 237, "header": "tr|E1BJA0-1|E1BJA0_BOVIN Isoform 1 of small monomeric GTPase OS=Bos taurus OX=9913 GN=RAB33A PE=3 SV=1 CANONICAL=E1BJA0-1" }, "locus": { "chromosome": "X", "start_pos": 14141101, "end_pos": 14131484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030324.5", "url": "https://www.ensembl.org/id/ENSBTAT00000030324.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030308.4", "url": "https://www.ensembl.org/id/ENSBTAP00000030308.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:510101", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510101", "resource": "KEGG Pathway" }, { "id": "R-BTA-8854214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854214", "resource": "Reactome", "description": "TBC/RABGAPs" }, { "id": "R-BTA-8873719", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8873719", "resource": "Reactome", "description": "RAB geranylgeranylation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZCU8-1", "protein_name": "small monomeric GTPase", "gene_name": "Rab33a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQPILGHGSLQPASAAGLASLELDSSMDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDAERQQGKVQTLEFPQEANSKTSCPC", "length": 237 }, "evidence": [ { "id": "E1BJA0", "url": "https://omabrowser.org/oma/group/E1BJA0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H3X0-1", "protein_name": "small monomeric GTPase", "gene_name": "Rab33a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAQPILGHGSLQPASAAGLASLELDSSMDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDSERQQGKVQKLEFPQEANSKASCPC", "length": 237 }, "evidence": [ { "id": "E1BJA0", "url": "https://omabrowser.org/oma/group/E1BJA0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P97950-1", "protein_name": "Ras-related protein Rab-33A", "gene_name": "Rab33a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQPILGHGSLQPASAAGLASLELDSSMDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDAERQQGKVQKLEFSQEANGKASCPC", "length": 237 }, "evidence": [ { "id": "E1BJA0", "url": "https://omabrowser.org/oma/group/E1BJA0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14088-1", "protein_name": "Ras-related protein Rab-33A", "gene_name": "RAB33A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQPILGHGSLQPASAAGLASLELDSSLDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDAERQQGKVQKLEFPQEANSKTSCPC", "length": 237 }, "evidence": [ { "id": "E1BJA0", "url": "https://omabrowser.org/oma/group/E1BJA0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "E1BJA0", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "E1BJA0", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "E1BJA0", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BJA0", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "E1BJA0", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "E1BJA0", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ], "pmid": "" }, { "name": "antigen processing and presentation", "id": "GO:0019882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019882", "evidence": [ { "database": "UniProtKB", "id": "E1BJA0", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "E1BJA0", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08E00-1", "Q5E9J3-1", "A6QP66-1", "Q2KHU8-1", "Q2KIA5-1", "F1MM29-1", "P08239-1", "P04896-1", "P63097-1", "Q7YS69-1", "Q0VCJ7-1", "A0AAA9SVR8-1", "P81948-1", "Q2KJ93-1", "A0AAA9TES1-1", "P61223-1", "Q2HJB8-1", "Q0IIG7-1", "Q3ZCJ7-1", "Q27957-1", "Q2HJ86-1", "A0A3Q1LMP2-1", "F1MB25-1", "Q58DS9-1", "A0AAA9S306-1", "A0A3Q1NEF8-1", "A4FV54-1", "A6H7I5-1", "F2Z4D5-1", "G3N1U2-1", "O18956-1", "P62998-1", "Q32KN8-1", "Q3MHP2-1", "Q3T054-1", "Q3T0F5-1", "Q3T0T7-1", "Q56JV3-1", "F1MNI4-1", "Q8HZJ5-1", "P61585-1", "P62833-1", "P68103-1", "Q08DI5-1", "Q2HJH2-1", "Q2T9U1-1", "Q2TBH7-1", "Q3MHP5-1", "Q3SX43-1", "Q3SYU2-1", "P81947-1", "P84080-1", "Q08DF4-1", "Q2KI07-1", "Q2TA29-1", "Q3T0D7-1", "A6QLJ3-1", "A6QNM2-1", "A6QR46-1", "Q1LZ78-1", "Q2KHZ2-1", "G3MYK6-1", "Q58D56-1", "Q32KW9-1", "P11023-1", "Q58DW6-1", "Q9TU25-1", "P10948-1", "Q2HJI8-1", "P10949-1", "Q0IIG8-1", "Q29RR0-1", "Q32PH8-1", "Q58DS5-1", "Q1RMR4-1", "Q3ZC27-1", "P49410-1", "A0A140T898-1", "E1BPU0-1", "A0AAA9S5W8-1", "A0AAA9SLN0-1", "A0AAF6Z672-1", "Q17R06-1", "Q58D72-1", "P82922-1", "Q2HJF8-1", "Q17QU4-1", "Q2YDM7-1", "A0AAA9T9T1-1", "A0A3Q1MDX0-1", "F1N2J9-1", "Q17QB7-1", "Q3SWY9-1", "Q5E9M9-1", "A0A3S5ZPA2-1", "A0AAA9SV95-1", "A0AAA9TWE6-1", "F1N6Y7-1", "F1N7V2-1", "A0AAA9SGM6-1", "A0AAA9TNQ2-1", "A0AAA9TS74-1", "F6Q1G9-1", "A0AAF6YXF5-1", "A5D7J5-1", "P04695-1", "Q3ZBW5-1", "A4FUD1-1", "A0A3Q1M0B9-1", "A6H7F2-1", "F1MHP4-1", "A0A3Q1MGR4-1", "A0A3Q1NCE9-1", "Q0P5E2-1", "Q32LJ6-1", "Q58DC5-1", "Q08DA0-1", "A0ABI0NND0-1", "E1BJA0-1", "A0A3Q1N147-1", "A0AAF6YME1-1", "F1MX39-1", "Q1RMJ6-1", "Q2HJ68-1", "Q2HJG3-1", "Q17QI8-1", "Q3SZA1-1", "A0ABI0NZ89-1", "A0ABI0P4Y3-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-BTA-8854612", "name": "TBC1D25 accelerates GTP hydrolysis by RAB33B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "autophagosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BJA0-1" ], "evidence": [ { "id": "R-BTA-8854612", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854612" } ] }, { "id": "R-BTA-8870466", "name": "RGGT:CHM binds RABs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0IIG7-1", "Q8HZJ5-1", "A0A140T898-1", "F1MNI4-1", "Q3MHP2-1", "A0A3S5ZPA2-1", "A6QR46-1", "Q3ZC27-1", "A0AAA9TS74-1", "A0AAA9SV95-1", "A0A3Q1MGR4-1", "P10948-1", "Q2TBH7-1", "F1N2J9-1", "P10949-1", "P11023-1", "Q17R06-1", "A0A3Q1MWA3-1", "F1N7V2-1", "A4FV54-1", "F2Z4D5-1", "Q58DW6-1", "Q17QB7-1", "Q17QU4-1", "Q1RMR4-1", "Q5E9B3-1", "Q5EA80-1", "E1BJA0-1" ], "evidence": [ { "id": "R-BTA-8870466", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8870466" } ] }, { "id": "R-BTA-8870469", "name": "RGGT geranylgeranylates RAB proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1131164" ], "output_participant_list": [], "enzyme_list": [ "Q0IIG7-1", "Q8HZJ5-1", "A0A140T898-1", "F1MNI4-1", "Q3MHP2-1", "A0A3S5ZPA2-1", "A6QR46-1", "Q3ZC27-1", "A0AAA9TS74-1", "A0AAA9SV95-1", "A0A3Q1MGR4-1", "P10948-1", "Q2TBH7-1", "F1N2J9-1", "P10949-1", "P11023-1", "Q17R06-1", "A0A3Q1MWA3-1", "F1N7V2-1", "A4FV54-1", "F2Z4D5-1", "Q58DW6-1", "Q17QB7-1", "Q17QU4-1", "Q1RMR4-1", "Q5E9B3-1", "Q5EA80-1", "E1BJA0-1" ], "evidence": [ { "id": "R-BTA-8870469", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8870469" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1131164", "participant_name": "geranylgeranyl diphosphate [cytosol]", "crossref": [ { "id": "48861", "database": "ChEBI", "url": "" }, { "id": "C00353", "database": "COMPOUND", "url": "" }, { "id": "3052", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000012495043", "database": "ZINC", "url": "" }, { "id": "HMDB0004486", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T898", "gene_name": "RAB13", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] } ] }, { "uniprot_ac": "A0A3Q1LMP2", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B9", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] } ] }, { "uniprot_ac": "A0A3Q1MDX0", "gene_name": "DNM3", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] } ] }, { "uniprot_ac": "A0A3Q1MGR4", "gene_name": "RAB37", "activity": [ { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KHU8" } ] } ] }, { "uniprot_ac": "Q2KHZ2", "gene_name": "HBS1L", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q2KHZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KHZ2" } ] } ] }, { "uniprot_ac": "Q2KI07", "gene_name": "ARL8B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q2KI07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI07" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q2KI07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI07" } ] } ] }, { "uniprot_ac": "Q2KIA5", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q2KIA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIA5" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "Q2KIA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIA5" } ] } ] }, { "uniprot_ac": "Q2KJ93", "gene_name": "CDC42", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q2KJ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ93" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q2KJ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ93" } ] } ] }, { "uniprot_ac": "Q2T9U1", "gene_name": "SRP54", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q2T9U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9U1" } ] }, { "ec_number": "3.6.5.4", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q2T9U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9U1" } ] }, { "ec_number": "3.6.5.4", "activity": "", "evidence": [ { "id": "Q2T9U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9U1" } ] } ] }, { "uniprot_ac": "Q2TA29", "gene_name": "RAB11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q2TA29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA29" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q2TA29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA29" } ] } ] }, { "uniprot_ac": "Q2TBH7", "gene_name": "RAB4A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q2TBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBH7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q2TBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBH7" } ] } ] }, { "uniprot_ac": "Q2YDM7", "gene_name": "LSG1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q2YDM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDM7" } ] } ] }, { "uniprot_ac": "Q32KN8", "gene_name": "TUBA3", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q32KN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KN8" } ] } ] }, { "uniprot_ac": "Q32KW9", "gene_name": "IRGC", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q32KW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KW9" } ] } ] }, { "uniprot_ac": "Q32LJ6", "gene_name": "RABL3", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q32LJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LJ6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q32LJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LJ6" } ] } ] }, { "uniprot_ac": "Q32PH8", "gene_name": "EEF1A2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q32PH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PH8" } ] } ] }, { "uniprot_ac": "Q3MHP2", "gene_name": "RAB11B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q3MHP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q3MHP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP2" } ] } ] }, { "uniprot_ac": "Q3MHP5", "gene_name": "DRG1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q3MHP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP5" } ] } ] }, { "uniprot_ac": "Q3SWY9", "gene_name": "RAB28", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q3SWY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q3SWY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY9" } ] } ] }, { "uniprot_ac": "Q3SX43", "gene_name": "RRAGA", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q3SX43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX43" } ] } ] }, { "uniprot_ac": "Q3SYU2", "gene_name": "EEF2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q3SYU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYU2" } ] } ] }, { "uniprot_ac": "Q3SZA1", "gene_name": "RHOF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q3SZA1", "database": "UniProtKB", "url": 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"id": "Q3T0F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q3T0F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0F5" } ] } ] }, { "uniprot_ac": "Q3T0T7", "gene_name": "SAR1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q3T0T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0T7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q3T0T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0T7" } ] } ] }, { "uniprot_ac": "Q3ZBW5", "gene_name": "RHOB", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q3ZBW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBW5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q3ZBW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBW5" } ] } ] }, { "uniprot_ac": "Q3ZC27", "gene_name": "RAB19", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q3ZC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC27" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q3ZC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC27" } ] } ] }, { "uniprot_ac": "Q3ZCJ7", "gene_name": "TUBA1C", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q3ZCJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCJ7" } ] } ] }, { "uniprot_ac": "Q56JV3", "gene_name": "RHEB", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q56JV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q56JV3" } ] } ] }, { "uniprot_ac": "Q58D56", "gene_name": "DRG2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q58D56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D56" } ] } ] }, { "uniprot_ac": "Q58D72", "gene_name": "ATL1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q58D72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D72" } ] } ] }, { "uniprot_ac": "Q58DC5", "gene_name": "GTPBP1", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q58DC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DC5" } ] }, { "ec_number": "3.6.5.3", "activity": "", "evidence": [ { "id": "Q58DC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DC5" } ] } ] }, { "uniprot_ac": "Q58DS5", "gene_name": "RAB13", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q58DS5", "database": 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"url": "https://www.uniprot.org/uniprotkb/Q58DW6" } ] } ] }, { "uniprot_ac": "Q5E9B3", "gene_name": "RABGGTB", "activity": [ { "ec_number": "2.5.1.60", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "Q5E9B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B3" } ] }, { "ec_number": "2.5.1.60", "activity": "", "evidence": [ { "id": "Q5E9B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B3" } ] } ] }, { "uniprot_ac": "Q5E9J3", "gene_name": "RASL11B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q5E9J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q5E9J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J3" } ] } ] }, { "uniprot_ac": "Q5E9M9", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5E9M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9M9" } ] } ] }, { "uniprot_ac": "Q5EA80", "gene_name": "RABGGTA", "activity": [ { "ec_number": "2.5.1.60", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "Q5EA80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA80" } ] }, { "ec_number": "2.5.1.60", "activity": "", "evidence": [ { "id": "Q5EA80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA80" } ] } ] }, { "uniprot_ac": "Q7YS69", "gene_name": "RHEBL1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q7YS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YS69" } ] } ] }, { "uniprot_ac": "Q8HZJ5", "gene_name": "RAB27B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q8HZJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8HZJ5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q8HZJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8HZJ5" } ] } ] }, { "uniprot_ac": "Q9TU25", "gene_name": "RAC2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q9TU25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9TU25" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q9TU25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9TU25" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJA0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 237, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJA0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJA0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.5.2", "ec_name": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "3.6.5.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2" }, { "id": "3.6.5.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.5.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJL2-1", "uniprot_ac": "E1BJL2", "uniprot_id": "E1BJL2_BOVIN", "mass": { "chemical_mass": 39219.0, "monoisotopic_mass": 39219.0 }, "refseq": { "ac": "NP_001192549", "name": "polycomb group RING finger protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192549" }, "gene_names": [ { "name": "PCGF6", "type": "recommended", "evidence": [ { "id": "E1BJL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJL2" } ] }, { "name": "PCGF6", "type": "synonym", "evidence": [ { "id": "NP_001192549", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192549" } ] } ], "protein_names": [ { "name": "Polycomb group RING finger protein 6", "type": "recommended", "evidence": [ { "id": "E1BJL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJL2/entry#names_and_taxonomy" } ] }, { "name": "RING finger protein 134", "type": "synonym", "evidence": [ { "id": "E1BJL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJL2/entry#names_and_taxonomy" } ] }, { "name": "polycomb group RING finger protein 6", "type": "synonym", "evidence": [ { "id": "NP_001192549", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192549" } ] } ], "function": [ { "annotation": "Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.", "evidence": [ { "database": "UniProtKB", "id": "E1BJL2", "url": "https://www.uniprot.org/uniprotkb/E1BJL2#function" }, { "database": "UniProtKB", "id": "ARBA00054318", "url": "https://www.uniprot.org/uniprotkb/ARBA00054318#function" }, { "database": "UniProtKB", "id": "A0AAA9SEW8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEW8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJL2", "url": "https://www.uniprot.org/uniprotkb/E1BJL2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PCGF6", "url": "https://www.uniprot.org/uniprotkb/E1BJL2", "locus": { "chromosome": "26", "start_pos": 23908102, "end_pos": 23939589, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009879", "url": "https://www.ensembl.org/id/ENSBTAG00000009879" } ] } } ], "crossref": [ { "id": "E1BJL2", "url": "https://alphafold.ebi.ac.uk/entry/E1BJL2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009879", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009879", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16738", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16738", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17085", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17085", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "507739", "url": "https://www.ncbi.nlm.nih.gov/gene/507739", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038037", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038037", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507739", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507739", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIMCSIC", "url": "https://omabrowser.org/oma/group/YIMCSIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MIR1", "url": "https://www.orthodb.org/?gene=A0A3Q1MIR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BJL2", "url": "https://www.orthodb.org/?gene=E1BJL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45893", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45893", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8953750", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8953750", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192549", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192549", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIR1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SEW8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SEW8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJL2", "url": "https://www.uniprot.org/uniprotkb/E1BJL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJL2-1", "url": "https://www.uniprot.org/uniprotkb/E1BJL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGLPAVTAGNAGAAKAEGAATMPPPPPVSPPALTPAPAAGEEGPPPLPEAGDPGCSGSRPPELEPERSLGRLRGRFEDEDEELEEDEDLEEEEEEEEEEEMSHFSLRLEGGRPDSEDEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPSSKGRTKKVLESVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLERYQTLREIRRAIGDAAMQDGLLVLHYGLVVSPLKIT", "length": 351, "header": "tr|E1BJL2-1|E1BJL2_BOVIN Isoform 1 of Polycomb group RING finger protein 6 OS=Bos taurus OX=9913 GN=PCGF6 PE=4 SV=1 CANONICAL=E1BJL2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MIR1-1", "url": "https://www.uniprot.org/uniprotkb/E1BJL2/entry#A0A3Q1MIR1-1", "sequence": { "sequence": "MEGLPAVTAGNAGAAKAEGAATMPPPPPVSPPALTPAPAAGEEGPPPLPEAGDPGCSGSRPPELEPERSLGRLRGRFEDEDEELEEDEDLEEEEEEEEEEEMSHFSLRLEGGRPDSEDEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPSSKGRTKKVLESVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQDGLLVLHYGLVVSPLKIT", "length": 322, "header": "tr|A0A3Q1MIR1-1|E1BJL2_BOVIN Computationally mapped isoform of Polycomb group RING finger protein 6 OS=Bos taurus OX=9913 GN=PCGF6 PE=4 SV=1 CANONICAL=E1BJL2-1" }, "locus": { "chromosome": "26", "start_pos": 23939587, "end_pos": 23909106, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078085.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078085.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070622.1", "url": "https://www.ensembl.org/id/ENSBTAP00000070622.1" } ] } }, { "isoform_ac": "A0AAA9SEW8-1", "url": "https://www.uniprot.org/uniprotkb/E1BJL2/entry#A0AAA9SEW8-1", "sequence": { "sequence": "MEGLPAVTAGNAGAAKAEGAATMPPPPPVSPPALTPAPAAGEEGPPPLPEAGDPGCSGSRPPELEPERSLGRLRGRFEDEDEELEEDEDLEEEEEEEEEEEMSHFSLRLEGGRPDSEDEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNISANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLERYQTLREIRRAIGDAAMQDGLLVLHYGLVVSPLKIT", "length": 276, "header": "tr|A0AAA9SEW8-1|E1BJL2_BOVIN Computationally mapped isoform of Polycomb group RING finger protein 6 OS=Bos taurus OX=9913 GN=PCGF6 PE=4 SV=1 CANONICAL=E1BJL2-1" }, "locus": { "chromosome": "26", "start_pos": 23939587, "end_pos": 23909106, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094632.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094632.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084696.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084696.1" } ] } }, { "isoform_ac": "E1BJL2-1", "url": "https://www.uniprot.org/uniprotkb/E1BJL2/entry#E1BJL2-1", "sequence": { "sequence": "MEGLPAVTAGNAGAAKAEGAATMPPPPPVSPPALTPAPAAGEEGPPPLPEAGDPGCSGSRPPELEPERSLGRLRGRFEDEDEELEEDEDLEEEEEEEEEEEMSHFSLRLEGGRPDSEDEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPSSKGRTKKVLESVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLERYQTLREIRRAIGDAAMQDGLLVLHYGLVVSPLKIT", "length": 351, "header": "tr|E1BJL2-1|E1BJL2_BOVIN Isoform 1 of Polycomb group RING finger protein 6 OS=Bos taurus OX=9913 GN=PCGF6 PE=4 SV=1 CANONICAL=E1BJL2-1" }, "locus": { "chromosome": "26", "start_pos": 23939587, "end_pos": 23909106, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013026.7", "url": "https://www.ensembl.org/id/ENSBTAT00000013026.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013026.5", "url": "https://www.ensembl.org/id/ENSBTAP00000013026.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507739", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507739", "resource": "KEGG Pathway" }, { "id": "R-BTA-8953750", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8953750", "resource": "Reactome", "description": "Transcriptional Regulation by E2F6" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZG86-1", "protein_name": "Polycomb group ring finger 6", "gene_name": "PCGF6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRPACRPAITGATRACAYAPGAGLGRSPPSARAMDAEVDAGSVVSGLSGGDGAGAGPADEDQEMEGAPSCSGSRSLPFEFERSRSESSGDEDDEDDEEEEMEEEELEGDSGVRFGTDDGELDSDDDRERMINLAELTPYILCSICKGYFIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVVNLEEREKKQMHDFYKERGLEVPKPAVPQPVPASRGRPRKVLGSVFRIPPELDISILLEFIGLWKRSLCVFQGRQRLDTWRNSSEGRWIWILLVSGLTQLEVKHTIFSIPEVDIICGDHLLEHYQTLREIRQVIGESAVQDGLLVLHYGLVVSPLTIP", "length": 365 }, "evidence": [ { "id": "E1BJL2", "url": "https://omabrowser.org/oma/group/E1BJL2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3L672-1", "protein_name": "Polycomb group RING finger protein 6", "gene_name": "PCGF6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGVPAVTTGNAGATKAEGAAAMPPPPPVSPPALTPAPSAGEEGPPPLPEAGAPGCSGSRPPELEPERSLGRLRSRFEDEDEELEEDEDLDEEEEEEEEEEMSHFSLRLEGGRPDSEDEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPLSKGRSKKVLESVFRIPPELDMSLLLEFIGANEGTGHIKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLERYQTLREIRRAIGDAAMQDGLLVLHYGLVVSPLKIT", "length": 351 }, "evidence": [ { "id": "E1BJL2", "url": "https://omabrowser.org/oma/group/E1BJL2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5XI70-1", "protein_name": "Polycomb group RING finger protein 6", "gene_name": "Pcgf6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEAETDATENKRASEAKRASAMLPPPPPPISPPALIPAPAAGEEGPASLAQAGAPGCSRSRPPELEPERSLGRLRGRFEDYDEELEEDEEMEEEEEEEEEMSHFSLRLESGRADSEDEEERLINLVELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVVNLEEREKKQMHDFYKERGLEVPKPAVPQPVPASKGRTKKALESVFRIPPELDVSLLLEFIGANEDTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLERYQTLREIRRAIGDTAMQDGLLVLHYGLVVSPLKIT", "length": 351 }, "evidence": [ { "id": "E1BJL2", "url": "https://omabrowser.org/oma/group/E1BJL2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99NA9-1", "protein_name": "Polycomb group RING finger protein 6", "gene_name": "Pcgf6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEAETDATENKRASEAKRASAMPPPPPPPPPISPPALIPAPAAGEEGPASLGQAGAAGCSRSRPPALEPERSLGRLRGRFEDYDEELEEEEEMEEEEEEEEEMSHFSLRLESGRADSEDEEERLINLVELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAAPQPVPSSKGKTKKVLESVFRIPPELDMSLLLEFIGANEDTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLERYQTLREIRRAIGDTAMQDGLLVLHYGLVVSPLKIT", "length": 353 }, "evidence": [ { "id": "E1BJL2", "url": "https://omabrowser.org/oma/group/E1BJL2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BYE7-1", "protein_name": "Polycomb group RING finger protein 6", "gene_name": "PCGF6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGVAVVTAGSVGAAKTEGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPSSKGRSKKVLESVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLEQYQTLREIRRAIGDAAMQDGLLVLHYGLVVSPLKIT", "length": 350 }, "evidence": [ { "id": "E1BJL2", "url": "https://omabrowser.org/oma/group/E1BJL2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BJL2", "url": "https://www.uniprot.org/uniprotkb/E1BJL2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "E1BJL2", "url": "https://www.uniprot.org/uniprotkb/E1BJL2" } ], "pmid": "" }, { "name": "PRC1 complex", "id": "GO:0035102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035102", "evidence": [ { "database": "UniProtKB", "id": "E1BJL2", "url": "https://www.uniprot.org/uniprotkb/E1BJL2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BJL2", "url": "https://www.uniprot.org/uniprotkb/E1BJL2" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "E1BJL2", "url": "https://www.uniprot.org/uniprotkb/E1BJL2" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BJL2", "url": "https://www.uniprot.org/uniprotkb/E1BJL2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BJL2", "url": "https://www.uniprot.org/uniprotkb/E1BJL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJL2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 351, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJL2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJL2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJL2" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 135, "end_pos": 174, "start_aa": "Cys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGC3-1", "uniprot_ac": "E1BGC3", "uniprot_id": "E1BGC3_BOVIN", "mass": { "chemical_mass": 133269.0, "monoisotopic_mass": 133269.0 }, "refseq": { "ac": "XP_002698943", "name": "wings apart-like protein homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698943" }, "gene_names": [ { "name": "WAPL", "type": "recommended", "evidence": [ { "id": "E1BGC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ] }, { "name": "WAPL", "type": "synonym", "evidence": [ { "id": "XP_002698943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698943" } ] } ], "protein_names": [ { "name": "Wings apart-like protein homolog", "type": "recommended", "evidence": [ { "id": "E1BGC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGC3/entry#names_and_taxonomy" } ] }, { "name": "WAPL cohesin release factor", "type": "synonym", "evidence": [ { "id": "E1BGC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGC3/entry#names_and_taxonomy" } ] }, { "name": "wings apart-like protein homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002698943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698943" } ] } ], "function": [ { "annotation": "Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3#function" }, { "database": "UniProtKB", "id": "ARBA00054706", "url": "https://www.uniprot.org/uniprotkb/ARBA00054706#function" }, { "database": "UniProtKB", "id": "A0A3Q1ML67", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML67#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "WAPL", "url": "https://www.uniprot.org/uniprotkb/E1BGC3", "locus": { "chromosome": "28", "start_pos": 41162101, "end_pos": 41237987, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012213", "url": "https://www.ensembl.org/id/ENSBTAG00000012213" } ] } } ], "crossref": [ { "id": "E1BGC3", "url": "https://alphafold.ebi.ac.uk/entry/E1BGC3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012213", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012213", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "534322", "url": "https://www.ncbi.nlm.nih.gov/gene/534322", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022771", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022771", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039874", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039874", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534322", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534322", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EANDTWN", "url": "https://omabrowser.org/oma/group/EANDTWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGC3", "url": "https://www.orthodb.org/?gene=E1BGC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22100:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22100:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07814", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07814", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2468052", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2468052", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2470946", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2470946", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002698943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698943", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1ML67", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1ML67-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGC3-1", "url": "https://www.uniprot.org/uniprotkb/E1BGC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSRFGKTYSRKGGNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQKRPNFKPDIQEVPKKPKIEEENTGDPFGFDSDDESLPVSSKNLAKGSSYTESSEAAQLEEVTSVLEANSKISHVMGEDSVVSDKCLRLEDTLLGKEKSTNRVLEDDASRSSCAKLMTSDKVENFSEEHEKNSHHIYKNAEDSTKKHNAETTVASGYKADEIKENDTWNSQLGKRSESPSETSSIKGSVRTGLYEWDNDFEDSRSEDCILNLDSDPLLEMKDEDFKNRLENLNEAIEEDMMQSVLRPSNCRTYCRANKAKSSQGASSFDKLMDGTSQALAKANSESSKDGLNQAKKGSVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDHDETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSSSNNAENLDFTEDLPGVPESVKKPPNKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPAPPVVKPQSVTVRLSSKEQNQKDDGVFKAPAPPPKVIKTVTIPTQPYQDIVTALKCRKEDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELEQDASSAKLLNEKDMNKIKEKIRRLCETVHNKHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSKDEDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIVSSAKALQHCEELIKQYNRAENSICLPDSKPLPQQNVTNHVGKAVEDCMRAIIGVLLNLTNDNEWGSTKTGEQDGLIGTAMNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCSFDSSFCSGEGDDSLRIAGQVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKADGAEEKNKKEEDDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC", "length": 1193, "header": "tr|E1BGC3-1|E1BGC3_BOVIN Isoform 1 of Wings apart-like protein homolog OS=Bos taurus OX=9913 GN=WAPL PE=3 SV=1 CANONICAL=E1BGC3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1ML67-1", "url": "https://www.uniprot.org/uniprotkb/E1BGC3/entry#A0A3Q1ML67-1", "sequence": { "sequence": "MTSRFGKTYSRKGGNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQKRPNFKPDIQEVPKKPKIEEENTGDPFGFDSDDESLPVSSKNLAKGSSYTESSEAAQLEEVTSVLEANSKISHVMGEDSVVSDKCLRLEDTLLGKEKSTNRVLEDDASRSSCAKLMTSDKVENFSEEHEKNSHHIYKNAEDSTKKHNAETTVASGYKADEIKENDTWNSQLGKRSESPSETSSIKGSVRTGLYEWDNDFEDSRSEDCILNLDSDPLLEMKDEDFKNRLENLNEAIEEDMMQSVLRPSNCRTYCRANKAKSSQGASSFDKLMDGTSQALAKANSESSKDGLNQAKKGSVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDHDETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSSSNNAEDLPGVPESVKKPPNKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPAPPVVKPQSVTVRLSSKEQNQKDDGVFKAPAPPPKVIKTVTIPTQPYQDIVTALKCRKEDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELEQDASSAKLLNEKDMNKIKEKIRRLCETVHNKHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSKDEDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIVSSAKALQHCEELIKQYNRAENSICLPDSKPLPQQNVTNHVGKAVEDCMRAIIGVLLNLTNDNEWGSTKTGEQDGLIGTAMNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCSFDSSFCSGEGDDSLRIAGQVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKADGAEEKNKKEEDDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC", "length": 1187, "header": "tr|A0A3Q1ML67-1|E1BGC3_BOVIN Computationally mapped isoform of Wings apart-like protein homolog OS=Bos taurus OX=9913 GN=WAPL PE=3 SV=2 CANONICAL=E1BGC3-1" }, "locus": { "chromosome": "28", "start_pos": 41235070, "end_pos": 41163105, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066703.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066703.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072396.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072396.2" } ] } }, { "isoform_ac": "E1BGC3-1", "url": "https://www.uniprot.org/uniprotkb/E1BGC3/entry#E1BGC3-1", "sequence": { "sequence": "MTSRFGKTYSRKGGNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQKRPNFKPDIQEVPKKPKIEEENTGDPFGFDSDDESLPVSSKNLAKGSSYTESSEAAQLEEVTSVLEANSKISHVMGEDSVVSDKCLRLEDTLLGKEKSTNRVLEDDASRSSCAKLMTSDKVENFSEEHEKNSHHIYKNAEDSTKKHNAETTVASGYKADEIKENDTWNSQLGKRSESPSETSSIKGSVRTGLYEWDNDFEDSRSEDCILNLDSDPLLEMKDEDFKNRLENLNEAIEEDMMQSVLRPSNCRTYCRANKAKSSQGASSFDKLMDGTSQALAKANSESSKDGLNQAKKGSVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDHDETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSSSNNAENLDFTEDLPGVPESVKKPPNKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPAPPVVKPQSVTVRLSSKEQNQKDDGVFKAPAPPPKVIKTVTIPTQPYQDIVTALKCRKEDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELEQDASSAKLLNEKDMNKIKEKIRRLCETVHNKHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSKDEDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIVSSAKALQHCEELIKQYNRAENSICLPDSKPLPQQNVTNHVGKAVEDCMRAIIGVLLNLTNDNEWGSTKTGEQDGLIGTAMNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCSFDSSFCSGEGDDSLRIAGQVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKADGAEEKNKKEEDDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC", "length": 1193, "header": "tr|E1BGC3-1|E1BGC3_BOVIN Isoform 1 of Wings apart-like protein homolog OS=Bos taurus OX=9913 GN=WAPL PE=3 SV=1 CANONICAL=E1BGC3-1" }, "locus": { "chromosome": "28", "start_pos": 41235070, "end_pos": 41163105, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016211.7", "url": "https://www.ensembl.org/id/ENSBTAT00000016211.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016211.5", "url": "https://www.ensembl.org/id/ENSBTAP00000016211.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534322", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534322", "resource": "KEGG Pathway" }, { "id": "R-BTA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-BTA-2468052", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2468052", "resource": "Reactome", "description": "Establishment of Sister Chromatid Cohesion" }, { "id": "R-BTA-2470946", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2470946", "resource": "Reactome", "description": "Cohesin Loading onto Chromatin" }, { "id": "R-BTA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ADT3-1", "protein_name": "Wings apart-like protein homolog", "gene_name": "Wapl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSRFGKTYSRKGGNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQKRPNFKPDIQEIPKKPKVEEEDTGDPFGFDSDDESLPVSSKSLAQGKGSSYSESSEAVQLEEVTSVLEANSKCSHAVGEDSFASDRCLLVEDSLIGKEKNTNRIPEDNANKSSCTKLITSDKVENFSEEHEKNSHHFHKNAEDSTKKPNAETVAASECKADETKTSDTWNSQSAKRTESPSESCPVKGSVRTGLYEWDNDFEDIRSEDCILSLDNDSLLEMKDEDLKNRIGGLENLNEAFEEDIIQSVLRPSNCRTYCRANKAKSSQGTSNFDKLMDGTSQTLAKANSESSKDGLNQAKKGSVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDHDETGGDEGGSGSSNYKIKYFGFDDLSESEDDDDDDCQVERKKDKKRTKTAPSPSQQPPPESSDNSQDSQSSTNNAENLDFTEDLPGVPESVKKPISKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPGPPIVKPQSVTVRLSSKEPNQKDDGVFKAPAPPLKVIKTVTIPTQPYQEIVTALKCRKEDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELEQDASSAKLLNEKDMNKIKEKIRRLCETVHNKHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSRDEDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIISSAKALQHCEDLIQQYNRAENSICIADSKPLPYQNVTNHVGKAVEDCMRAIIGVLLNLTNDNEWGSTKTGEQEGLIGTAMNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCSFDSSFSSGEGDHNLRLAGQVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGAEEKQKKEDEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC", "length": 1198 }, "evidence": [ { "id": "E1BGC3", "url": "https://omabrowser.org/oma/group/E1BGC3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z5K2-1", "protein_name": "Wings apart-like protein homolog", "gene_name": "WAPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSRFGKTYSRKGGNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQKRPNFKPDIQEIPKKPKVEEESTGDPFGFDSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKISHVVVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNSHHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWDNDFEDIRSEDCILSLDSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNCRTYCRANKTKSSQGASNFDKLMDGTSQALAKANSESSKDGLNQAKKGGVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVKPQSVTVRLSSKEPNQKDDGVFKAPAPPSKVIKTVTIPTQPYQDIVTALKCRREDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELEQDASSAKLLNEKDMNKIKEKIRRLCETVHNKHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSRDEDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIVSSAKALQHCEELIQQYNRAEDSICLADSKPLPHQNVTNHVGKAVEDCMRAIIGVLLNLTNDNEWGSTKTGEQDGLIGTALNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCSFDSSICSGEGDDSLRIGGQVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC", "length": 1190 }, "evidence": [ { "id": "E1BGC3", "url": "https://omabrowser.org/oma/group/E1BGC3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" }, { "name": "germinal vesicle", "id": "GO:0042585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042585", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" }, { "name": "synaptonemal complex", "id": "GO:0000795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000795", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" }, { "name": "negative regulation of sister chromatid cohesion", "id": "GO:0045875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045875", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" }, { "name": "negative regulation of DNA replication", "id": "GO:0008156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008156", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP-dependent protein-DNA unloader activity", "id": "GO:0140083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140083", "evidence": [ { "database": "UniProtKB", "id": "E1BGC3", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1142, "end_pos": 1144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1170, "end_pos": 1172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 718, "end_pos": 720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 791, "end_pos": 793, "annotation": "n_glycosylation_sequon" }, { "start_pos": 871, "end_pos": 873, "annotation": "n_glycosylation_sequon" }, { "start_pos": 920, "end_pos": 922, "annotation": "n_glycosylation_sequon" }, { "start_pos": 942, "end_pos": 944, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGC3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1193, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGC3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGC3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGC3" }, { "id": "PS51271", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51271" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WAPL", "eco_id": "ECO_0000259", "start_pos": 629, "end_pos": 1172, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1142, "end_pos": 1144 }, { "start_pos": 1170, "end_pos": 1172 }, { "start_pos": 15, "end_pos": 17 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 718, "end_pos": 720 }, { "start_pos": 791, "end_pos": 793 }, { "start_pos": 871, "end_pos": 873 }, { "start_pos": 920, "end_pos": 922 }, { "start_pos": 942, "end_pos": 944 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKN5-1", "uniprot_ac": "E1BKN5", "uniprot_id": "E1BKN5_BOVIN", "mass": { "chemical_mass": 19938.0, "monoisotopic_mass": 19938.0 }, "refseq": {}, "gene_names": [ { "name": "IL20", "type": "recommended", "evidence": [ { "id": "E1BKN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKN5" } ] } ], "protein_names": [ { "name": "Interleukin family protein", "type": "recommended", "evidence": [ { "id": "E1BKN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKN5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Immune regulatory cytokine.", "evidence": [ { "database": "UniProtKB", "id": "E1BKN5", "url": "https://www.uniprot.org/uniprotkb/E1BKN5#function" }, { "database": "UniProtKB", "id": "RU368043", "url": "https://www.uniprot.org/uniprotkb/RU368043#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKN5", "url": "https://www.uniprot.org/uniprotkb/E1BKN5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IL20", "url": "https://www.uniprot.org/uniprotkb/E1BKN5", "locus": { "chromosome": "16", "start_pos": 4656675, "end_pos": 4653645, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002757", "url": "https://www.ensembl.org/id/ENSBTAG00000002757" } ] } } ], "crossref": [ { "id": "E1BKN5", "url": "https://alphafold.ebi.ac.uk/entry/E1BKN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002757", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002757", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RLCHARM", "url": "https://omabrowser.org/oma/group/RLCHARM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48482", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48482", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48482:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48482:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00726", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00726", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8854691", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854691", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MMM3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKN5", "url": "https://www.uniprot.org/uniprotkb/E1BKN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKN5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGSGLPLCLLSAVFYLFWTPSAGLKTLHLGSCVITTNLQGIRSGFSEIRDSVQAKDEIIDVRILRKTQSLQGTKPADQCCLLHHILRLYLDRVFKNYQPPDHHIFRKVSRLANSLLTIKKDLQLCHAHMSCPCGEEAKEKYSQILSHFEELPPQAVVVKALGELDILLQWMEEAD", "length": 176, "header": "tr|E1BKN5-1|E1BKN5_BOVIN Isoform 1 of Interleukin family protein OS=Bos taurus OX=9913 GN=IL20 PE=3 SV=2 CANONICAL=E1BKN5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MMM3-1", "url": "https://www.uniprot.org/uniprotkb/E1BKN5/entry#A0A3Q1MMM3-1", "sequence": { "sequence": "MRGSGLPLCLLSAVFYLFWTPSAGLKTLHLGSCVITTNLQGIRSGFSEIRDSVQAKDEIIDVRILRKTQSLQGTKPADQCCLLHHILRLYLDRVFKNYQPPDHHIFRKVSRLANSLLTIKKDLQLCLPPQAVVVKALGELDILLQWMEEAD", "length": 151, "header": "tr|A0A3Q1MMM3-1|E1BKN5_BOVIN Computationally mapped isoform of Interleukin family protein OS=Bos taurus OX=9913 GN=IL20 PE=3 SV=2 CANONICAL=E1BKN5-1" }, "locus": { "chromosome": "16", "start_pos": 4656672, "end_pos": 4653645, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079416.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079416.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070685.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070685.2" } ] } }, { "isoform_ac": "E1BKN5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKN5/entry#E1BKN5-1", "sequence": { "sequence": "MRGSGLPLCLLSAVFYLFWTPSAGLKTLHLGSCVITTNLQGIRSGFSEIRDSVQAKDEIIDVRILRKTQSLQGTKPADQCCLLHHILRLYLDRVFKNYQPPDHHIFRKVSRLANSLLTIKKDLQLCHAHMSCPCGEEAKEKYSQILSHFEELPPQAVVVKALGELDILLQWMEEAD", "length": 176, "header": "tr|E1BKN5-1|E1BKN5_BOVIN Isoform 1 of Interleukin family protein OS=Bos taurus OX=9913 GN=IL20 PE=3 SV=2 CANONICAL=E1BKN5-1" }, "locus": { "chromosome": "16", "start_pos": 4656672, "end_pos": 4653645, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003574.3", "url": "https://www.ensembl.org/id/ENSBTAT00000003574.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003574.2", "url": "https://www.ensembl.org/id/ENSBTAP00000003574.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8854691", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854691", "resource": "Reactome", "description": "Interleukin-20 family signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I6E3-1", "protein_name": "Interleukin family protein", "gene_name": "Il20", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKGFGFAFGLFSVVGFLLWTPLTGLQTLHLGSCVITANLQAIQKEFSEILDTVQAEDENIDIRILRTTESLQDIKHSDRCCFLRHLVRFYLDRVFKFYQTPDHHILRKTSSLANSFLIIKKDLSICHSRMVCHCGEEAMKKYNHVLSHFTELERQEAVVKALGELGILLRWMEEMI", "length": 176 }, "evidence": [ { "id": "E1BKN5", "url": "https://omabrowser.org/oma/group/E1BKN5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A2T8-1", "protein_name": "Interleukin family protein", "gene_name": "Il20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGFRLAFGLFSVVGFLLWTPLTGLKTLHLGSCVITANLQAIQKEFSEIRHSVQAEDENIDVRILRTTESLKDTKLSDRCCFLRHLVRFYLDRVFKVYQTPDHHTLRKISSLANSFLIIKKDLSVCHSHMACHCGEEAMEKYNQILSHFTELELQAAVVKALGELGILLRWMEEML", "length": 176 }, "evidence": [ { "id": "E1BKN5", "url": "https://omabrowser.org/oma/group/E1BKN5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JKV9-1", "protein_name": "Interleukin-20", "gene_name": "Il20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGFGLAFGLFSAVGFLLWTPLTGLKTLHLGSCVITANLQAIQKEFSEIRDSVQAEDTNIDIRILRTTESLKDIKSLDRCCFLRHLVRFYLDRVFKVYQTPDHHTLRKISSLANSFLIIKKDLSVCHSHMACHCGEEAMEKYNQILSHFIELELQAAVVKALGELGILLRWMEEML", "length": 176 }, "evidence": [ { "id": "E1BKN5", "url": "https://omabrowser.org/oma/group/E1BKN5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NYY1-1", "protein_name": "Interleukin-20", "gene_name": "IL20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKASSLAFSLLSAAFYLLWTPSTGLKTLNLGSCVIATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLYLDRVFKNYQTPDHYTLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFEKLEPQAAVVKALGELDILLQWMEETE", "length": 176 }, "evidence": [ { "id": "E1BKN5", "url": "https://omabrowser.org/oma/group/E1BKN5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BKN5", "url": "https://www.uniprot.org/uniprotkb/E1BKN5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "E1BKN5", "url": "https://www.uniprot.org/uniprotkb/E1BKN5" } ], "pmid": "" }, { "name": "interleukin-20 receptor binding", "id": "GO:0045517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045517", "evidence": [ { "database": "UniProtKB", "id": "E1BKN5", "url": "https://www.uniprot.org/uniprotkb/E1BKN5" } ], "pmid": "" }, { "name": "interleukin-22 receptor binding", "id": "GO:0045518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045518", "evidence": [ { "database": "UniProtKB", "id": "E1BKN5", "url": "https://www.uniprot.org/uniprotkb/E1BKN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of biosynthetic process", "id": "GO:0009891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009891", "evidence": [ { "database": "UniProtKB", "id": "E1BKN5", "url": "https://www.uniprot.org/uniprotkb/E1BKN5" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "E1BKN5", "url": "https://www.uniprot.org/uniprotkb/E1BKN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKN5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 176, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKN5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKN5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGM1-1", "uniprot_ac": "E1BGM1", "uniprot_id": "E1BGM1_BOVIN", "mass": { "chemical_mass": 120696.0, "monoisotopic_mass": 120696.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF451", "type": "recommended", "evidence": [ { "id": "E1BGM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ] } ], "protein_names": [ { "name": "E3 SUMO-protein ligase ZNF451", "type": "recommended", "evidence": [ { "id": "E1BGM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGM1/entry#names_and_taxonomy" } ] }, { "name": "E3 SUMO-protein transferase ZNF451", "type": "synonym", "evidence": [ { "id": "E1BGM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGM1/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 451", "type": "synonym", "evidence": [ { "id": "E1BGM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGM1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins. Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation. Has no activity with SUMO1. Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11'. Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9'. Plays a role in regulating the transcription of AR targets.", "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1#function" }, { "database": "UniProtKB", "id": "ARBA00059985", "url": "https://www.uniprot.org/uniprotkb/ARBA00059985#function" }, { "database": "UniProtKB", "id": "A0A3Q1MPE1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPE1#function" }, { "database": "UniProtKB", "id": "A0A3Q1N592", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N592#function" }, { "database": "UniProtKB", "id": "A0A3Q1NJV6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJV6#function" }, { "database": "UniProtKB", "id": "A0AAA9SGD5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGD5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF451", "url": "https://www.uniprot.org/uniprotkb/E1BGM1", "locus": { "chromosome": "23", "start_pos": 3043566, "end_pos": 3142229, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018879", "url": "https://www.ensembl.org/id/ENSBTAG00000018879" } ] } } ], "crossref": [ { "id": "E1BGM1", "url": "https://alphafold.ebi.ac.uk/entry/E1BGM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018879", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018879", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18721", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18721", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "529894", "url": "https://www.ncbi.nlm.nih.gov/gene/529894", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MPE1", "url": "https://www.orthodb.org/?gene=A0A3Q1MPE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N592", "url": "https://www.orthodb.org/?gene=A0A3Q1N592", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NJV6", "url": "https://www.orthodb.org/?gene=A0A3Q1NJV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BGM1", "url": "https://www.orthodb.org/?gene=E1BGM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408:SF61", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF61", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18479", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18479", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23101", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23101", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23103", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23108", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23108", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MPE1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N592", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N592", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N592-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N592-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NJV6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NJV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGD5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGD5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNN2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRB5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRB5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGM1-1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDPGSEIIECIPPAGPEASESTVEENEDDIQFVSEGPLRPVLEYIDLVSSDDDEPSTSQREDKHKDHIDHQKDKVALTLARLARHVEVEKQQKEEKNRAFREKIDFQHAHGLQELEFIRGHSDTEAARLCVDQWLKMPGLKTGTINSGTKGSFRRGSQIRASGKPISCPIMHCNKEFDNGHLLLGHLKRFDHSPCDPTITLHGPFISSFACVVCYKNFVTQQQYRDHLFAKEAADDGHKNNLLPQIIQCFACPNCFLLFSSKDECLKHMSGKNHFHQSFKLGDDKAVAQPISFPSFAKKLLISLCKDVPFQVKCVACHQTLRSHMELTAHFRVRCRNAGPVALAEKSIAQVAEKFLLRGYCPHCNHVFVDETSTWNHKQNLGHKVRVINSMEESVLLYCHSNEGNKPLSDLHLLQDGSKFSSLKRNMSSQESSSQDCSTVPKKKMNLGVKSLGGVVCFQKERSLVKTWFCECHQRFPSEDAVEKHVFSANTMCYKCVVCGKVCEDLGVIRLHMSRIHGGAHLNNFLFWCRTCKKELRRKEAIMAHVTEFHSGHRYFYETDEVAGDTSPSSSTVLVSDLTAENPSSALTIVDHSPANRPPRGKWQCRICEDMFDSQECVKQHCMSLTSHQFHRYSCTHCKKTFHKMETLQRHCQDEHNSEVKMKYFCGLCDLSFNVEDAFLTHYKEHHSTDYVFVSEKTEPSIKTESDFPVIETGNLLTCGCRESYLCKVNRREDHGRCLQTLLGQGRLWFRCGVCSATTQSLGDLHTHVRQAHADLETPPRGLIKCGTCTKAFQDPESAQQHFHTKHCSLRGPVGARLSAEPKSPPPARAERKPRQTADGLQTAEPDRAAEMELSGQSADEEVVELPDLDYLRTMTHIVFVDFDNWSNFFGHLPGHLNQGTFIWGFQGGNTNWKPPAHCKVYNYLNRIGCFFLHPRCSKRKDAADFAICMHAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTTKECDSDDNLGIKSASVGEEFRSAEGLRELFISLHIKSFTSCHCLVVICGIRRSY", "length": 1067, "header": "tr|E1BGM1-1|E1BGM1_BOVIN Isoform 1 of E3 SUMO-protein ligase ZNF451 OS=Bos taurus OX=9913 GN=ZNF451 PE=3 SV=3 CANONICAL=E1BGM1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MPE1-1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1/entry#A0A3Q1MPE1-1", "sequence": { "sequence": "MRDNLHFCSQLFEDKHKDHIDHQKDKVALTLARLARHVEVEKQQKEEKNRAFREKIDFQHAHGLQELEFIRGHSDTEAARLCVDQWLKMPGLKTGTINSGTKGSFRRGSQIRASGKPISCPIMHCNKEFDNGHLLLGHLKRFDHSPCDPTITLHGPFISSFACVVCYKNFVTQQQYRDHLFAKEAADDGHKNNLLPQIIQCFACPNCFLLFSSKDECLKHMSGKNHFHQSFKLGDDKAVAQPISFPSFAKKLLISLCKDVPFQVKCVACHQTLRSHMELTAHFRVRCRNAGPVALAEKSIAQVAEKFLLRGYCPHCNHVFVDETSTWNHKQNLGHKVRVINSMEESVLLYCHSNEGNKPLSDLHLLQDGSKFSSLKRNMSSQESSSQDCSTVPKKKMNLGVKSLGGVVCFQKERSLVKTWFCECHQRFPSEDAVEKHVFSANTMCYKCVVCGKVCEDLGVIRLHMSRIHGGAHLNNFLFWCRTCKKELRRKEAIMAHVTEFHSGHRYFYETDEVAGDTSPSSSTVLVSDLTAENPSSALTIVDHSPANRPPRGKWQCRICEDMFDSQECVKQHCMSLTSHQFHRYSCTHCKKTFHKMETLQRHCQDEHNSEVKMKYFCGLCDLSFNVEDAFLTHYKEHHSTDYVFVSEKTEPSIKTESDFPVIETGNLLTCGCRESYLCKVNRREDHGRCLQTLLGQGRLWFRCGVCSATTQSLGDLHTHVRQAHADLETPPRGLIKCGTCTKAFQDPESAQQHFHTKHCSLRGPVGARLSAEPKSPPPARAERKPRQTADGLQTAEPDRAAEMELSGQSADEEVVELPDLDYLRTMTHIVFVDFDNWSNFFGHLPGHLNQGTFIWGFQGGNTNWKPPAHCKVYNYLNRIGCFFLHPRCSKRKDAADFAICMHAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTTKECDSDDNLGIKSASVGEEFRSAEDVELEEAIRRSLEEM", "length": 1003, "header": "tr|A0A3Q1MPE1-1|E1BGM1_BOVIN Computationally mapped isoform of E3 SUMO-protein ligase ZNF451 OS=Bos taurus OX=9913 GN=ZNF451 PE=3 SV=2 CANONICAL=E1BGM1-1" }, "locus": { "chromosome": "23", "start_pos": 3129756, "end_pos": 3055674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083403.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083403.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073302.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073302.2" } ] } }, { "isoform_ac": "A0A3Q1N592-1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1/entry#A0A3Q1N592-1", "sequence": { "sequence": "MGDPGSEIIECIPPAGPEASESTVEENEDDIQFVSEGPLRPVLEYIDLVSSDDDEPSTSQREDKHKDHIDHQKDKVALTLARLARHVEVEKQQKEEKNRAFREKIDFQHAHGLQELEFIRGHSDTEAARLCVDQWLKMPGLKTGTINSGTKGSFRRGSQIRASGKPISCPIMHCNKEFDNGHLLLGHLKRFDHSPCDPTITLHGPFISSFACVVCYKNFVTQQQYRDHLFAKEAADDGHKNNLLPQIIQCFACPNCFLLFSSKDECLKHMSGKNHFHQSFKLGDDKAVAQPISFPSFAKKLLISLCKDVPFQVKCVACHQTLRSHMELTAHFRVRCRNAGPVALAEKSIAQVAEKFLLRGYCPHCNHVFVDETSTWNHKQNLGHKVRVINSMEESVLLYCHSNEGNKPLSDLHLLQDGSKFSSLKRNMSSQESSSQDCSTVPKKKMNLGVKSLGGVVCFQKERSLVKTWFCECHQRFPSEDAVEKHVFSANTMCYKCVVCGKVCEDLGVIRLHMSRIHGGAHLNNFLFWCRTCKKELRRKEAIMAHVTEFHSGHRYFYETDEVAGDTSPSSSTVLVSDLTAENPSSALTIVDHSPANRPPRGKWQCRICEDMFDSQECVKQHCMSLTSHQFHRYSCTHCKKTFHKMETLQRHCQDEHNSEVKMKYFCGLCDLSFNVEDAFLTHYKEHHSTDYVFVSEKTEPSIKTESDFPVIETGNLLTCGCRESYLCKVNRREDHGRCLQTLLGQGRLWFRCGVCSATTQSLGDLHTHVRQAHADLETPPRGLIKCGTCTKAFQDPESAQQHFHTKHCSLRGPVGARLSAEPKSPPPARAERKPRQTADGLQTAEPDRAAEMELSGQSADEEVVELPDLDYLRTMTHIVFVDFDNWSNFFGHLPGHLNQGTFIWGFQGGNTNWKPPAHCKVYNYLNRIGCFFLHPRCSKRKDAADFAICMHAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTTKDVELEEAIRRSLEEM", "length": 1029, "header": "tr|A0A3Q1N592-1|E1BGM1_BOVIN Computationally mapped isoform of E3 SUMO-protein ligase ZNF451 OS=Bos taurus OX=9913 GN=ZNF451 PE=3 SV=1 CANONICAL=E1BGM1-1" }, "locus": { "chromosome": "23", "start_pos": 3142228, "end_pos": 3055674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070238.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070238.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065277.1", "url": "https://www.ensembl.org/id/ENSBTAP00000065277.1" } ] } }, { "isoform_ac": "A0A3Q1NJV6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1/entry#A0A3Q1NJV6-1", "sequence": { "sequence": "MGDPGSEIIECIPPAGPEASESTVEENEDDIQFVSEGPLRPVLEYIDLVSSDDDEPSTSQREDKHKDHIDHQKDKVALTLARLARHVEVEKQQKEEKNRAFREKIDFQHAHGLQELEFIRGHSDTEAARLCVDQWLKMPGLKTGTINSGTKGSFRRGSQIRASGKPISCPIMHCNKEFDNGHLLLGHLKRFDHSPCDPTITLHGPFISSFACVVCYKNFVTQQQYRDHLFAKEAADDGHKNNLLPQIIQCFACPNCFLLFSSKDECLKHMSGKNHFHQSFKLGDDKAVAQPISFPSFAKKLLISLCKDVPFQVKCVACHQTLRSHMELTAHFRVRCRNAGPVALAEKSIAQVAEKFLLRGYCPHCNHVFVDETSTWNHKQNLGHKVRVINSMEESVLLYCHSNEGNKPLSDLHLLQDGSKFSSLKRNMSSQESSSQDCSTVPKKKMNLGVKSLGGVVCFQKERSLVKTWFCECHQRFPSEDAVEKHVFSANTMCYKCVVCGKVCEDLGVIRLHMSRIHGGAHLNNFLFWCRTCKKELRRKEAIMAHVTEFHSGHRYFYETDEVAGDTSPSSSTVLVSDLTAENPSSALTIVDHSPANRPPRGKWQCRICEDMFDSQECVKQHCMSLTSHQFHRYSCTHCKKTFHKMETLQRHCQDEHNSEVKMKYFCGLCDLSFNVEDAFLTHYKEHHSTDYVFVSEKTEPSIKTESDFPVIETGNLLTCGCRESYLCKVNRREDHGRCLQTLLGQGRLWFRCGVCSATTQSLGDLHTHVRQAHADLETPPRGLIKCGTCTKAFQDPESAQQHFHTKHCSLRGPVGARLSAEPKSPPPARAERKPRQTADGLQTAEPDRAAEMELSGQSADEEVVELPDLDYLRTMTHIVFVDFDNWSNFFGHLPGHLNQGTFIWGFQGGNTNWKPPAHCKVYNYLNRIGCFFLHPRCSKRKDAADFAICMHAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTTKEPHFD", "length": 1019, "header": "tr|A0A3Q1NJV6-1|E1BGM1_BOVIN Computationally mapped isoform of E3 SUMO-protein ligase ZNF451 OS=Bos taurus OX=9913 GN=ZNF451 PE=3 SV=1 CANONICAL=E1BGM1-1" }, "locus": { "chromosome": "23", "start_pos": 3142228, "end_pos": 3075002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076535.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076535.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072495.1", "url": "https://www.ensembl.org/id/ENSBTAP00000072495.1" } ] } }, { "isoform_ac": "A0AAA9SGD5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1/entry#A0AAA9SGD5-1", "sequence": { "sequence": "MGDPGSEIIECIPPAGPEASESTVEENEDDIQFVSEGPLRPVLEYIDLVSSDDDEPSTSQREDKHKDHIDHQKDKVALTLARLARHVEVEKQQKEEKNRAFREKIDFQHAHGLQELEFIRGHSDTEAARLCVDQWLKMPGLKTGTINSGTKGSFRRGSQIRASGKPISCPIMHCNKEFDNGHLLLGHLKRFDHSPCDPTITLHGPFISSFACVVCYKNFVTQQQYRDHLFAKEAADDGHKNNLLPQIIQCFACPNCFLLFSSKDECLKHMSGKNHFHQSFKLGDDKAVAQPISFPSFAKKLLISLCKDVPFQVKCVACHQTLRSHMELTAHFRVRCRNAGPVALAEKSIAQVAEKFLLRGYCPHCNHVFVDETSTWNHKQNLGHKVRVINSMEESVLLYCHSNEGNKPLSDLHLLQDGSKFSSLKRNMSSQESSSQDCSTVPKKKMNLGVKSLGGVVCFQKERSLVKTWFCECHQRFPSEDAVEKHVFSANTMCYKCVVCGKVCEDLGVIRLHMSRIHGGAHLNNFLFWCRTCKKELRRKEAIMAHVTEFHSGHRYFYETDEVAGDTSPSSSTVLVSDLTAENPSSALTIVDHSPANRPPRGKWQCRICEDMFDSQECVKQHCMSLTSHQFHRYSCTHCKKTFHKMETLQRHCQDEHNSEVKMKYFCGLCDLSFNVEDAFLTHYKEHHSTDYVFVSEKTEPSIKTESDFPVIETGNLLTCGCRESYLCKVNRREDHGRCLQTLLGQGRLWFRCGVCSATTQSLGDLHTHVRQAHADLETPPRGLIKCGTCTKAFQDPESAQQHFHTKHCSLRGPVGARLSAEPKSPPPARAERKPRQTADGLQTAEPDRAAEMELSGQSADEEVVELPDLDYLRTMTHIVFVDFDNWSNFFGHLPGHLNQGTFIWGFQGGNTNWKPPAHCKVYNYLNRIGCFFLHPRCSKRKDAADFAICMHAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTTKECDSDDNLGIKSASVGEEFRSAEGS", "length": 1039, "header": "tr|A0AAA9SGD5-1|E1BGM1_BOVIN Computationally mapped isoform of E3 SUMO-protein ligase ZNF451 OS=Bos taurus OX=9913 GN=ZNF451 PE=3 SV=1 CANONICAL=E1BGM1-1" }, "locus": { "chromosome": "23", "start_pos": 3142228, "end_pos": 3059970, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101095.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101095.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081552.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081552.1" } ] } }, { "isoform_ac": "A0AAA9SNN2-1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1/entry#A0AAA9SNN2-1", "sequence": { "sequence": "MGDPGSEIIECIPPAGPEASESTVEENEDDIQFVSEGPLRPVLEYIDLVSSDDDEPSTSQRERMPESKAPSSESRRPEMCSGCRAPPPSGDSSSSSGRCASSPQRMVSHPSSVENPLETQRNDHSNSDIKISETETLEPSQNYQSLPPSPLLVPQESMASSEVEEGLPVESPASQHGRDALLYLQTQVAEMSRVIRDLQSRSCFRFHHSRTGEASSVPWDISTSREEQISAVEEEAECKSPSADDKGQPADPSQSSFTGLLKRMEQRGVIKRVTLQSEAEPCEGKPDCVTSKKRLVPPLHPLLKIATAEVFKDPADCHPSSFMGHRVYPVAKDTSPFQPNPPAGGPIVEALEHSRRGGTTSPLDSTSKEMEVMGCRFYHAASIAARAASYMAYMTQYQRKLWEDMEDLVHDPEFDRGKARCIISNGMDAGLWQLCTTRDIMDSVVRVMAMAIDYRRQAWLRLTSLTKKTQEKISHLPFDGTCLFGQDVNAVVAEENSVKENDYKDHSKYYNQHRCFYSHDQKAHYHSRGYSRGDWYRPRNHPYRHRKRADSPERHGYKN", "length": 559, "header": "tr|A0AAA9SNN2-1|E1BGM1_BOVIN Computationally mapped isoform of E3 SUMO-protein ligase ZNF451 OS=Bos taurus OX=9913 GN=ZNF451 PE=3 SV=1 CANONICAL=E1BGM1-1" }, "locus": { "chromosome": "23", "start_pos": 3142228, "end_pos": 3130958, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089062.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089062.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087937.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087937.1" } ] } }, { "isoform_ac": "A0ABI0NRB5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1/entry#A0ABI0NRB5-1", "sequence": { "sequence": "MGDPGSEIIECIPPAGPEASESTVEENEDDIQFVSEGPLRPVLEYIDLVSSDDDEPSTSQREMPYRTGSFSSRTTWPQKIYSVWKKGCEKFL", "length": 92, "header": "tr|A0ABI0NRB5-1|A0ABI0NRB5_BOVIN Computationally mapped isoform of Zinc finger protein 451 OS=Bos taurus OX=9913 GN=ZNF451 PE=4 SV=1 CANONICAL=E1BGM1-1" }, "locus": { "chromosome": "23", "start_pos": 3142228, "end_pos": 3133463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153783.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153783.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106137.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106137.1" } ] } }, { "isoform_ac": "E1BGM1-1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1/entry#E1BGM1-1", "sequence": { "sequence": "MGDPGSEIIECIPPAGPEASESTVEENEDDIQFVSEGPLRPVLEYIDLVSSDDDEPSTSQREDKHKDHIDHQKDKVALTLARLARHVEVEKQQKEEKNRAFREKIDFQHAHGLQELEFIRGHSDTEAARLCVDQWLKMPGLKTGTINSGTKGSFRRGSQIRASGKPISCPIMHCNKEFDNGHLLLGHLKRFDHSPCDPTITLHGPFISSFACVVCYKNFVTQQQYRDHLFAKEAADDGHKNNLLPQIIQCFACPNCFLLFSSKDECLKHMSGKNHFHQSFKLGDDKAVAQPISFPSFAKKLLISLCKDVPFQVKCVACHQTLRSHMELTAHFRVRCRNAGPVALAEKSIAQVAEKFLLRGYCPHCNHVFVDETSTWNHKQNLGHKVRVINSMEESVLLYCHSNEGNKPLSDLHLLQDGSKFSSLKRNMSSQESSSQDCSTVPKKKMNLGVKSLGGVVCFQKERSLVKTWFCECHQRFPSEDAVEKHVFSANTMCYKCVVCGKVCEDLGVIRLHMSRIHGGAHLNNFLFWCRTCKKELRRKEAIMAHVTEFHSGHRYFYETDEVAGDTSPSSSTVLVSDLTAENPSSALTIVDHSPANRPPRGKWQCRICEDMFDSQECVKQHCMSLTSHQFHRYSCTHCKKTFHKMETLQRHCQDEHNSEVKMKYFCGLCDLSFNVEDAFLTHYKEHHSTDYVFVSEKTEPSIKTESDFPVIETGNLLTCGCRESYLCKVNRREDHGRCLQTLLGQGRLWFRCGVCSATTQSLGDLHTHVRQAHADLETPPRGLIKCGTCTKAFQDPESAQQHFHTKHCSLRGPVGARLSAEPKSPPPARAERKPRQTADGLQTAEPDRAAEMELSGQSADEEVVELPDLDYLRTMTHIVFVDFDNWSNFFGHLPGHLNQGTFIWGFQGGNTNWKPPAHCKVYNYLNRIGCFFLHPRCSKRKDAADFAICMHAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTTKECDSDDNLGIKSASVGEEFRSAEGLRELFISLHIKSFTSCHCLVVICGIRRSY", "length": 1067, "header": "tr|E1BGM1-1|E1BGM1_BOVIN Isoform 1 of E3 SUMO-protein ligase ZNF451 OS=Bos taurus OX=9913 GN=ZNF451 PE=3 SV=3 CANONICAL=E1BGM1-1" }, "locus": { "chromosome": "23", "start_pos": 3142228, "end_pos": 3055696, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025130.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025130.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025130.6", "url": "https://www.ensembl.org/id/ENSBTAP00000025130.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ], "pmid": "" }, { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ], "pmid": "" }, { "name": "negative regulation of transcription initiation by RNA polymerase II", "id": "GO:0060633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060633", "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ], "pmid": "" }, { "name": "SUMO ligase activity", "id": "GO:0061665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061665", "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "E1BGM1", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGM1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1067, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGM1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGM1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGM1" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 198, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 427, "end_pos": 429 }, { "start_pos": 886, "end_pos": 888 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 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"uniprot_ac": "E1BIU2", "uniprot_id": "E1BIU2_BOVIN", "mass": { "chemical_mass": 19405.0, "monoisotopic_mass": 19405.0 }, "refseq": {}, "gene_names": [ { "name": "RHEX", "type": "recommended", "evidence": [ { "id": "E1BIU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU2" } ] } ], "protein_names": [ { "name": "Regulator of hemoglobinization and erythroid cell expansion", "type": "synonym", "evidence": [ { "id": "E1BIU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIU2", "url": "https://www.uniprot.org/uniprotkb/E1BIU2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RHEX", "url": "https://www.uniprot.org/uniprotkb/E1BIU2", "locus": { "chromosome": "16", "start_pos": 3851859, "end_pos": 3828772, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008513", "url": "https://www.ensembl.org/id/ENSBTAG00000008513" } ] } } ], "crossref": [ { "id": "E1BIU2", "url": "https://alphafold.ebi.ac.uk/entry/E1BIU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008513", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008513", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "616928", "url": "https://www.ncbi.nlm.nih.gov/gene/616928", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616928", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616928", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKPNFWT", "url": "https://omabrowser.org/oma/group/HKPNFWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIU2", "url": "https://www.orthodb.org/?gene=E1BIU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38491", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38491", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38491:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38491:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MS05", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MS05-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST27", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST27-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIU2", "url": "https://www.uniprot.org/uniprotkb/E1BIU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIU2-1", "url": "https://www.uniprot.org/uniprotkb/E1BIU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAQVMEVWHGVVIAVVSLILQTCLLAVINYLLSRHMAKEIERILKGARSQAPSLCPTHCCPPAAEERKETRAERNVLVPEPRYRHDSDTSSDSSDSSNSSPPTTSQVTKDVNYTQVVFAAPGDRRNDSVLDYENIKEATDYVNVNPKRQKPDFWTFVNPAVSEPVEYTQVVM", "length": 173, "header": "tr|E1BIU2-1|E1BIU2_BOVIN Isoform 1 of Regulator of hemoglobinization and erythroid cell expansion OS=Bos taurus OX=9913 GN=RHEX PE=4 SV=3 CANONICAL=E1BIU2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MS05-1", "url": "https://www.uniprot.org/uniprotkb/E1BIU2/entry#A0A3Q1MS05-1", "sequence": { "sequence": "MLAQVMEVWHGVVIAVVSLILQTCLLAVINYLLSRHMDDSDTSSDSSDSSNSSPPTTSQVTKDVNYTQVVFAAPGDRRNDSVLDYENIKEATDYVNVNPKRQKPDFWTFVNPAVSEPVEYTQVVM", "length": 125, "header": "tr|A0A3Q1MS05-1|E1BIU2_BOVIN Computationally mapped isoform of Regulator of hemoglobinization and erythroid cell expansion OS=Bos taurus OX=9913 GN=RHEX PE=4 SV=2 CANONICAL=E1BIU2-1" }, "locus": { "chromosome": "16", "start_pos": 3850868, "end_pos": 3847383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067001.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067001.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072683.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072683.2" } ] } }, { "isoform_ac": "A0AAA9ST27-1", "url": "https://www.uniprot.org/uniprotkb/E1BIU2/entry#A0AAA9ST27-1", "sequence": { "sequence": "MEVWHGVVIAVVSLILQTCLLAVINYLLSRHMAKEIERILKGARSQAPSLCPTHCCPPAAEERKETRAERNVLVPEPRYRHDSDTSSDSSDSSNSSPPTTSQVTKDVNYTQVVFAAPGDRRNDSVLDYENIKEATDYVNVNPKRQKPDFWTFVNPAVSEPVEYTQVVM", "length": 168, "header": "tr|A0AAA9ST27-1|E1BIU2_BOVIN Computationally mapped isoform of Regulator of hemoglobinization and erythroid cell expansion OS=Bos taurus OX=9913 GN=RHEX PE=4 SV=1 CANONICAL=E1BIU2-1" }, "locus": { "chromosome": "16", "start_pos": 3850868, "end_pos": 3847619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093706.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093706.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087271.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087271.1" } ] } }, { "isoform_ac": "E1BIU2-1", "url": "https://www.uniprot.org/uniprotkb/E1BIU2/entry#E1BIU2-1", "sequence": { "sequence": "MLAQVMEVWHGVVIAVVSLILQTCLLAVINYLLSRHMAKEIERILKGARSQAPSLCPTHCCPPAAEERKETRAERNVLVPEPRYRHDSDTSSDSSDSSNSSPPTTSQVTKDVNYTQVVFAAPGDRRNDSVLDYENIKEATDYVNVNPKRQKPDFWTFVNPAVSEPVEYTQVVM", "length": 173, "header": "tr|E1BIU2-1|E1BIU2_BOVIN Isoform 1 of Regulator of hemoglobinization and erythroid cell expansion OS=Bos taurus OX=9913 GN=RHEX PE=4 SV=3 CANONICAL=E1BIU2-1" }, "locus": { "chromosome": "16", "start_pos": 3850868, "end_pos": 3847383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011220.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011220.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011220.7", "url": "https://www.ensembl.org/id/ENSBTAP00000011220.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616928", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616928", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UTN8-1", "protein_name": "Regulator of hemoglobinization and erythroid cell expansion", "gene_name": "RHEX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTEEMKLWQGVVIAVVSLVLQACLLAAINYLLSRHMVKENERILKEARLQVPILSPAQPHAPAVKEIKEARAERNPPASEPRYRHDSDTSSDSSDSSDSSPPTHQATKDVNYTQVIFSAPGGRRNESVLDYENIKETTDYVNVNPKTHKPNFWAFVNPASEPVEYTQVAL", "length": 171 }, "evidence": [ { "id": "E1BIU2", "url": "https://omabrowser.org/oma/group/E1BIU2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6ZWK4-1", "protein_name": "Regulator of hemoglobinization and erythroid cell expansion protein", "gene_name": "RHEX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLTEVMEVWHGLVIAVVSLFLQACFLTAINYLLSRHMAHKSEQILKAASLQVPRPSPGHHHPPAVKEMKETQTERDIPMSDSLYRHDSDTPSDSLDSSCSSPPACQATEDVDYTQVVFSDPGELKNDSPLDYENIKEITDYVNVNPERHKPSFWYFVNPALSEPAEYDQVAM", "length": 172 }, "evidence": [ { "id": "E1BIU2", "url": "https://omabrowser.org/oma/group/E1BIU2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BIU2", "url": "https://www.uniprot.org/uniprotkb/E1BIU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of erythrocyte differentiation", "id": "GO:0045648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045648", "evidence": [ { "database": "UniProtKB", "id": "E1BIU2", "url": "https://www.uniprot.org/uniprotkb/E1BIU2" } ], "pmid": "" }, { "name": "erythropoietin-mediated signaling pathway", "id": "GO:0038162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038162", "evidence": [ { "database": "UniProtKB", "id": "E1BIU2", "url": "https://www.uniprot.org/uniprotkb/E1BIU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "erythropoietin receptor binding", "id": "GO:0005128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005128", "evidence": [ { "database": "UniProtKB", "id": "E1BIU2", "url": "https://www.uniprot.org/uniprotkb/E1BIU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIU2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 173, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIU2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIU2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 127, "end_pos": 129 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFF0-1", "uniprot_ac": "E1BFF0", "uniprot_id": "E1BFF0_BOVIN", "mass": { "chemical_mass": 123338.0, "monoisotopic_mass": 123338.0 }, "refseq": { "ac": "NP_001179012", "name": "protein unc-13 homolog D", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179012" }, "gene_names": [ { "name": "UNC13D", "type": "recommended", "evidence": [ { "id": "E1BFF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ] }, { "name": "UNC13D", "type": "synonym", "evidence": [ { "id": "NP_001179012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179012" } ] } ], "protein_names": [ { "name": "Unc-13 homolog D", "type": "synonym", "evidence": [ { "id": "E1BFF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF0/entry#names_and_taxonomy" } ] }, { "name": "protein unc-13 homolog D", "type": "synonym", "evidence": [ { "id": "NP_001179012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179012" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UNC13D", "url": "https://www.uniprot.org/uniprotkb/E1BFF0", "locus": { "chromosome": "19", "start_pos": 55785637, "end_pos": 55769744, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013556", "url": "https://www.ensembl.org/id/ENSBTAG00000013556" } ] } } ], "crossref": [ { "id": "E1BFF0", "url": "https://alphafold.ebi.ac.uk/entry/E1BFF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013556", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013556", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08676", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08676", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506146", "url": "https://www.ncbi.nlm.nih.gov/gene/506146", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:506146", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506146", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICKTKAF", "url": "https://omabrowser.org/oma/group/ICKTKAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MS42", "url": "https://www.orthodb.org/?gene=A0A3Q1MS42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BFF0", "url": "https://www.orthodb.org/?gene=E1BFF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45999", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45999", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45999:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45999:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179012", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179012", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MS42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MS42-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVT9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVT9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFF0-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMLFSRPQRRPPLMRQAIKIRRRGVRDLQDTRPPRAQEIEPSSHHLSPEERALLYEEALYTVLYRLGQPEPNHVGESSELLRYLQEAFRMEPEEHQQMLKRVQQLEKPVFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQGMTVSGGSPGLRRRQKAVVRHTIPEEQTHRTQVITQTLNPVWDETFILEFEDISNASFHLDMWDMDTVESVRQKLGELTDLHGLRRMFKEARKDKGQDDFLGNVVLRLQDLRCREDHWYPLEPCTDTYPDRGQCHLQFQFIHKRRATKASRSQPSYTVHLHLLQQLVSHEVTQHQAGSTSWDGSLSSQAATILFLHATQKDLSDFHRSLAQWLAYSRLYQSLEFPSSCLLFPITSIEYQWIQGRLKAEQLEELATSFSSLLAYGLSLIRRFRSVFPLSVPDSPARLQSLLRVLVQMCKMKAFGELCPNSDPLPSLVSEALRAGTVGWFHLKQQHHQPMVQGLLEMGKALLSLVQDIIGDLHQCQRTWNKIFHNVLKIDLFSMAFLELQWLVAKRVQDHIGAVGGSVTLEVGESLFQLYVSLKELYQLGPLPSERDGVLALEGFHRWFRPAIPSWLQKTYSVALARVQRAVQMDQLVPLGELTKHSTSAVDLSTCFAQISHTAQQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSAGQKDQGQAANMLCVVVNDMEQLRLVIGKLPTQLAWEALEQRVGPVLEQEQLQNTLHAQLQGALAGLGHEIRTGVRTLAEQLEAGIAKHIQKLVGIRESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLSLLWTHTLTVLAEVAASQRSCPRACSRLKFALQNLEVCFYAEGCGLPPEALHTATFQALQRDLELQAASSRELIHKYFCSRLQQQAATTSEELGAVTVKASYRPSEQKLRVELLSASNLLPLDSNGSSDPFVQLTLEPRHEFPELAPRETQKHKKDLHPLFDETFEFLVPAEPCQKDGACLLLSVLDHDTLGTDDLEGEAFLPLCSVPGLTGMEEPGEVPQTRLPLTYPAPNGDPILQLLESRKGDREAQAFVRLRRQRAKKASQHGPRPGR", "length": 1090, "header": "tr|E1BFF0-1|E1BFF0_BOVIN Isoform 1 of Unc-13 homolog D OS=Bos taurus OX=9913 GN=UNC13D PE=3 SV=3 CANONICAL=E1BFF0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MS42-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF0/entry#A0A3Q1MS42-1", "sequence": { "sequence": "MDPSHGRPGDKEGGPGAGPPGGLPQEQIEPSSHHLSPEERALLYEEALYTVLYRLGQPEPNHVGESSELLRYLQEAFRMEPEEHQQMLKRVQQLEKPVFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQGMTVSGGSPGLRRRQKAVVRHTIPEEQTHRTQVITQTLNPVWDETFILEFEDISNASFHLDMWDMDTVESVRQKLGELTDLHGLRRMFKEARKDKGQDDFLGNVVLRLQDLRCREDHWYPLEPCTDTYPDRGQCHLQFQFIHKRRATKASRSQPSYTVHLHLLQQLVSHEVTQHQAGSTSWDGSLSSQAATILFLHATQKDLSDFHRSLAQWLAYSRLYQSLEFPSSCLLFPITSIEYQWIQGRLKAEQLEELATSFSSLLAYGLSLIRRFRSVFPLSVPDSPARLQSLLRVLVQMCKMKAFGELCPNSDPLPSLVSEALRAGTVGWFHLKQQHHQPMVQGLLEMGKALLSLVQDIIGDLHQCQRTWNKIFHNVLKIDLFSMAFLELQWLVAKRVQDHIGAVGGSVTLEVGESLFQLYVSLKELYQLGPLPSERDGVLALEGFHRWFRPAIPSWLQKTYSVALARVQRAVQMDQLVPLGELTKHSTSAVDLSTCFAQISHTAQQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSAGQKDQGQAANMLCVVVNDMEQLRLVIGKLPTQLAWEALEQRVGPVLEQEQLQNTLHAQLQGALAGLGHEIRTGVRTLAEQLEAGIAKHIQKLVGIRESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLSLLWTHTLTVLAEVAASQRSCPRACSRLKFALQNLEVCFYAEGCGLPPEALHTATFQALQRDLELQAASSRELIHKYFCSRLQQQAATTSEELGAVTVKASYRPSEQKLRVELLSASNLLPLDSNGSSDPFVQLTLEPRHEFPELAPRETQKHKKDLHPLFDETFEFLVPAEPCQKDGACLLLSVLDHDTLGTDDLEGEAFLPLCSVPGLTGMEEPGEVPQTRLPLTYPAPNGDPILQLLESRKGDREAQAFVRLRRQRAKKASQHGPRPGRAARQAWRY", "length": 1086, "header": "tr|A0A3Q1MS42-1|E1BFF0_BOVIN Computationally mapped isoform of Unc-13 homolog D OS=Bos taurus OX=9913 GN=UNC13D PE=3 SV=2 CANONICAL=E1BFF0-1" }, "locus": { "chromosome": "19", "start_pos": 55784865, "end_pos": 55770907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074408.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074408.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072749.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072749.2" } ] } }, { "isoform_ac": "A0AAA9SVT9-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF0/entry#A0AAA9SVT9-1", "sequence": { "sequence": "MDPSHGRPGDKEGGPGAGPPGGLPQEQIEPSSHHLSPEERALLYEEALYTVLYRLGQPEPNHVGESSELLRYLQEAFRMEPEEHQQMLKRVQQLEKPVFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQGMTVSGGSPGLRRRQKAVVRHTIPEEQTHRTQVITQTLNPVWDETFILEFEDISNASFHLDMWDMDTVESVRQKLGELTDLHGLRRMFKEARKDKGQDDFLGNVVLRLQDLRCREDHWYPLEPCTDTYPDRGQCHLQFQFIHKRRATKASRSQPSYTVHLHLLQQLVSHEVTQHQAGSTSWDGSLSSQAATILFLHATQKDLSDFHRSLAQWLAYSRLYQSLEFPSSCLLFPITSIEYQWIQGRLKAEQLEELATSFSSLLAYGLSLIRRFRSVFPLSVPDSPARLQSLLRVLVQMCKMKAFGELCPNSDPLPSLVSEALRAGTVGWFHLKQQHHQPMVQGLLEMGKALLSLVQDIIGDLHQCQRTWNKIFHNVLKIDLFSMAFLELQWLVAKRVQDHIGAVGGSVTLEVGESLFQLYVSLKELYQLGPLPSERDGVLALEGFHRWFRPAIPSWLQKTYSVALARVQRAVQMDQLVPLGELTKHSTSAVDLSTCFAQISHTAQQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSAGQKDQGQAANMLCVVVNDMEQLRLVIGKLPTQLAWEALEQRVGPVLEQEQLQNTLHAQLQGALAGLGHEIRTGVRTLAEQLEAGIAKHIQKLVGIRESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLSLLWTHTLTVLAEVAASQRSCPRACSRLKFALQNLEVCFYAEGCGLPPEALHTATFQALQRDLELQAASSRELIHKYFCSRLQQQAATTSEELGAVTVKASYRPSEQKLRVELLSASNLLPLDSNGSSDPFVQLTLEPRHEFPELAPRETQKHKKDLHPLFDETFEFLVPAEPCQKDGACLLLSVLDHDTLGTDDLEGEAFLPLCSVPGLTGMEEPGEVPQTRLPLTYPAPNGDPILQLLESRKGDREAQAFVRLRRQRAKKASQHGPRPGR", "length": 1078, "header": "tr|A0AAA9SVT9-1|E1BFF0_BOVIN Computationally mapped isoform of Unc-13 homolog D OS=Bos taurus OX=9913 GN=UNC13D PE=3 SV=1 CANONICAL=E1BFF0-1" }, "locus": { "chromosome": "19", "start_pos": 55784113, "end_pos": 55770907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102570.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102570.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089438.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089438.1" } ] } }, { "isoform_ac": "E1BFF0-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF0/entry#E1BFF0-1", "sequence": { "sequence": "MAMLFSRPQRRPPLMRQAIKIRRRGVRDLQDTRPPRAQEIEPSSHHLSPEERALLYEEALYTVLYRLGQPEPNHVGESSELLRYLQEAFRMEPEEHQQMLKRVQQLEKPVFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQGMTVSGGSPGLRRRQKAVVRHTIPEEQTHRTQVITQTLNPVWDETFILEFEDISNASFHLDMWDMDTVESVRQKLGELTDLHGLRRMFKEARKDKGQDDFLGNVVLRLQDLRCREDHWYPLEPCTDTYPDRGQCHLQFQFIHKRRATKASRSQPSYTVHLHLLQQLVSHEVTQHQAGSTSWDGSLSSQAATILFLHATQKDLSDFHRSLAQWLAYSRLYQSLEFPSSCLLFPITSIEYQWIQGRLKAEQLEELATSFSSLLAYGLSLIRRFRSVFPLSVPDSPARLQSLLRVLVQMCKMKAFGELCPNSDPLPSLVSEALRAGTVGWFHLKQQHHQPMVQGLLEMGKALLSLVQDIIGDLHQCQRTWNKIFHNVLKIDLFSMAFLELQWLVAKRVQDHIGAVGGSVTLEVGESLFQLYVSLKELYQLGPLPSERDGVLALEGFHRWFRPAIPSWLQKTYSVALARVQRAVQMDQLVPLGELTKHSTSAVDLSTCFAQISHTAQQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSAGQKDQGQAANMLCVVVNDMEQLRLVIGKLPTQLAWEALEQRVGPVLEQEQLQNTLHAQLQGALAGLGHEIRTGVRTLAEQLEAGIAKHIQKLVGIRESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLSLLWTHTLTVLAEVAASQRSCPRACSRLKFALQNLEVCFYAEGCGLPPEALHTATFQALQRDLELQAASSRELIHKYFCSRLQQQAATTSEELGAVTVKASYRPSEQKLRVELLSASNLLPLDSNGSSDPFVQLTLEPRHEFPELAPRETQKHKKDLHPLFDETFEFLVPAEPCQKDGACLLLSVLDHDTLGTDDLEGEAFLPLCSVPGLTGMEEPGEVPQTRLPLTYPAPNGDPILQLLESRKGDREAQAFVRLRRQRAKKASQHGPRPGR", "length": 1090, "header": "tr|E1BFF0-1|E1BFF0_BOVIN Isoform 1 of Unc-13 homolog D OS=Bos taurus OX=9913 GN=UNC13D PE=3 SV=3 CANONICAL=E1BFF0-1" }, "locus": { "chromosome": "19", "start_pos": 55784113, "end_pos": 55770279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018027.7", "url": "https://www.ensembl.org/id/ENSBTAT00000018027.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018027.6", "url": "https://www.ensembl.org/id/ENSBTAP00000018027.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:506146", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506146", "resource": "KEGG Pathway" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RUP2-1", "protein_name": "Protein unc-13 homolog D", "gene_name": "Unc13d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATHLSHPQRRPLLRQAIKIRRRRVRDLQDPPPQATQEVQVQSHHFSPEERDLLYEEALYTVLHRLGQPEPNHVKEASELLSYLQEAFQVQPEEHQQMLRRVRELEKPVFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQKVGVAEGSPVSRRRQKAVVKHTIPEEETHRTQVKSQTLNPVWDETFILEFEDIANASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQDDFLGNVVLRLQDLRCREDQWFPLEPCTETYPDRGQCHLQFQFIHKRRATAASRSQPSYTVHFHLLQQLVSHEVTQHQAGSTSWDASLSPQAVTILFLHATQKDLSDFHQSMAQWLAYSRLYQSLEFPSSCLLHPITSIEYQWIQGRLKAEQREELATSFTSLLAYGLSLIRKFRSVFPLSVSDSPSRLQSLLRVLVQMCKMKAFGELCPDSAPLSQLVSEALRMGTVEWFHLMQQHHQPMVQGILEAGKALLNLVQDVMGDLYQCRRTWNKIFHNVLKIDLFSMAFLELQWLVAKRVQDHTVAAGNLVSPDIGESLFQLYVSLKELCQLGPVPSDSREVLALDGFHRWFQPAIPSWLQKTYSVALERVQRAVQMDTLVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSAVQKDQSQAADMLCVVVNNMEQLRLIIDKLPTQLAWEALEQRVGAVLEEGQLQNTLHAQLQGALAGLGHEIRTGVRTLAEQLEVGIATHIQKLIGVKESVLPEDAILPLMKFLEVKLCYMNTNLVQENFSSLLTLLWTHTLTVLVEVASSQRSSSLASGRLKVALQNLEVCFHAEGCGLPPEALHTDTFQALQNDLELQAASSRELIQKYFCSRIQQQAETTSERLGAVTVKVSYRASEQRLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPEVAPRETQKHKKELHPLFDETFEFLVPAEPCQKAWACLLLTVLDHDRLGADDLEGEAFLPLCRVPGLTDCAEPGEAPQMRLPLTYPAPNGDPILRLLESRKGDREAQAFVKLRRQRAKQASQHAP", "length": 1085 }, "evidence": [ { "id": "E1BFF0", "url": "https://omabrowser.org/oma/group/E1BFF0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6NFN1-1", "protein_name": "Protein unc-13 homolog D", "gene_name": "unc13d", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVPVQDGASSQGENLLLPPKETHSDTSGSGKIRPRQSSPARRLGMTRRQNRKDFKDSENPEESEKRHKEKELKPLYKELLYTITHRLGKPHIKQQYSQKQFQDYIREAFTMTEDEHKTLSEKVQSSLAPTYCLVVTVKQAKGILGKDISGFSDPYCLLTILSEDKESPGGGASNKPQKAVVRESAKGQVLQTSIKKQTLNPIWDETFKLEFENINGNFHMEMWDKDEEVSLVQKFDEFCTNIHGIKRMIKDAKKEKGQDDFLGNVVLKLKDLHCTEDTWYNLEPRTETYPDRGRCHLQLKFIHKERDETLSAGRSPYVNYCGILQQFVQAHISKQQDSNPWKGELCGEGTALLEYYANQNDISPFLQDLAKWVAYSKLYQSLEVDSTVLFQQLTSIEYHWDQQELPHQQKQELGDSLHGFLQYGLCLVSKYRDIYPPTTKTTPRLHTLLRVLVQICKTRAFQKLNPAQFDLHVEVTDAVVNGTEEWFNIKKGLHQPMTKDLLETVSALSRLIGEVQEDVRLSKDVWNKVFVSAVQLDVFTVVYQKLDTLLAEELRATLSQLENQMDQPLANSLFPVYLSLQTIHKDKAFLQKRAKLLQLTSFHEDFRDALPYWLNKAFSTTMERVKKAVHVDQLQPLQSGTVPIKHSSSAVDIAACLHPIAQLWDQLSWPDPEEAFMLMVKLTEDVCKIASTYCQMLKARVKELSEDSDQESAIKMLCVVVNDLEHLHTVLTRLPKQLNWAGLRERTRLVIGETQFQNTLPSQLQHTQSLLNREIRSAVDRLGKKLKTDIESHVRSMASRQRFPSRDTEEAVVPLMKYLEKELQYMNENLVQENFNSLLTPLWMNSVKILHQISQQEDSNLVYFQRLLYTLQCLEQCFYAEGNGLPLETLHTEEYKVLRANLTQNSLTSNQLIEKFFERKVWEQKVFNGEKYGAVTLITSYKRSENKLHVEVLNAVNLIPLDSNGSSDPFVQLSLEPRHLFPEVEQRSTKIKSCDLNPLFEESFEFLISLQQCQSPGACLLVTVLDHDTLRSDDFEGEAFLSLKAVPGVGGGLQNPEPAQIRLPLMHPKPNSENTLRLLEARKGEKEAQAFIKLRRQREKKSQEA", "length": 1105 }, "evidence": [ { "id": "E1BFF0", "url": "https://omabrowser.org/oma/group/E1BFF0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q70J99-1", "protein_name": "Protein unc-13 homolog D", "gene_name": "UNC13D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATLLSHPQQRPPFLRQAIKIRRRRVRDLQDPPPQMAPEIQPPSHHFSPEQRALLYEDALYTVLHRLGHPEPNHVTEASELLRYLQEAFHVEPEEHQQTLQRVRELEKPIFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTLNPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQDDFLGNVVLRLQDLRCREDQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSASRSQPSYTVHLHLLQQLVSHEVTQHEAGSTSWDGSLSPQAATVLFLHATQKDLSDFHQSMAQWLAYSRLYQSLEFPSSCLLHPITSIEYQWIQGRLKAEQQEELAASFSSLLTYGLSLIRRFRSVFPLSVSDSPARLQSLLRVLVQMCKMKAFGELCPNTAPLPQLVTEALQTGTTEWFHLKQQHHQPMVQGIPEAGKALLGLVQDVIGDLHQCQRTWDKIFHNTLKIHLFSMAFRELQWLVAKRVQDHTTVVGDVVSPEMGESLFQLYISLKELCQLRMSSSERDGVLALDNFHRWFQPAIPSWLQKTYNEALARVQRAVQMDELVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSSGQKDQGQAANMLCVVVNDMEQLRLVIGKLPAQLAWEALEQRVGAVLEQGQLQNTLHAQLQSALAGLGHEIRTGVRTLAEQLEVGIAKHIQKLVGVRESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLTLLWTHTLTVLVEAAASQRSSSLASNRLKIALQNLEICFHAEGCGLPPKALHTATFQALQRDLELQAASSRELIRKYFCSRIQQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREVPGLSGSEEPGEVPQTRLPLTYPAPNGDPILQLLEGRKGDREAQVFVRLRRHRAKQASQHALRPAP", "length": 1090 }, "evidence": [ { "id": "E1BFF0", "url": "https://omabrowser.org/oma/group/E1BFF0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R189-1", "protein_name": "Protein unc-13 homolog D", "gene_name": "Unc13d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATHLSHPQRRPPLLRQAVKIRRRRVRDLQDPPPQATPEVQVQSHHFSPEERDLLYEEALYTVLHRLGQPEPNHVKEASELLCYLQEAFQVQPEEHQQMLQRVRELEKPIFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQKVGVPEGSPVSRRRQKAVVRHTIPEEETHRTQVKTQTLNPVWDETFILEFEDITNASFHLDMWDLDTVESVRHKLGELTDLHGLRRIFKEARKDKGQDDFLGNVMLRLQDLRCREDQWFPLEPCTETYPDRGQCHLQFQFIHKRRATVASRSQPSYTVHFHLLQQLVSHEVTQHQAGGTSWGRIAESQAVTILFLHATQKDLSDFHQSMAQWLAYSRLYQSLEFPSSCLLHPITSIEYQWIQGRLKAEQREELATSFTSLLAYGLSLIRKFRSVFPLSVSDSPSRLQSLLRVLVQMCKMKAFGELCPDSAPLPQLVSEALRMGTVEWFHLMQQHHQPMVQGILEAGKALLSLVQDVMGDLYQCRRTWNKIFHNVLKIDLFTMAFLELQWLVAKRVQDHTAAVGDLVSPDVGESLFQLYVSLREFCQLGPSDSHEVLALDGFHRWFQSAIPSWLQRTYSVALERVQRAVQMDSLVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSAVQKDQSQAADMLCVVVNNVERLRLIIDKLPTQLAWEALEQRVGAVLEQGQLQNTLHTQLQGALAGLGHEIRTGVRTLAEQLEVGIATHIQKLIDAKGSILPEDAILPLMKFLEVKLCYMNTNLVQENFSSLLTLLWTHTLTVLVEAAASHRNSSLASSRLKVALQNLEICFHAEGCGLPPEALHTDTFLALQSDLELQAASSRELIQKYFRSRIQQQAETTSERLGAVTVKASYRASEQKLHVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAPRETQKHKKELHPLFDETFEFLVPAEPCQKDGACLLLTVLDHDRLGADDLEGEAFLPLCRVPGLTGCVEPGEAPQMRLPLTYPAPNGDPILRLLESRKGDREAQAFVKLRRQRAKQASQHAPATEP", "length": 1088 }, "evidence": [ { "id": "E1BFF0", "url": "https://omabrowser.org/oma/group/E1BFF0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" }, { "name": "Weibel-Palade body", "id": "GO:0033093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033093", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" }, { "name": "positive regulation of regulated secretory pathway", "id": "GO:1903307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903307", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" }, { "name": "positive regulation of substrate adhesion-dependent cell spreading", "id": "GO:1900026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900026", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" }, { "name": "regulation of mast cell degranulation", "id": "GO:0043304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043304", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" }, { "name": "secretion", "id": "GO:0046903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046903", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "E1BFF0", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 943, "end_pos": 945, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFF0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1090, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFF0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFF0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 237, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BFF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" }, { "id": "PS51258", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51258" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MHD1", "eco_id": "ECO_0000259", "start_pos": 557, "end_pos": 677, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BFF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF0" }, { "id": "PS51259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MHD2", "eco_id": "ECO_0000259", "start_pos": 788, "end_pos": 895, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 813, "end_pos": 815 }, { "start_pos": 943, "end_pos": 945 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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Classification" ] }, { "id": "PF15268", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15268", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MSL1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MSL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG86", "url": "https://www.uniprot.org/uniprotkb/E1BG86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG86-1", "url": "https://www.uniprot.org/uniprotkb/E1BG86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIRAFSFPVSPERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGAEAEDEEDADEDEDAAAARRAAAALEEQLEALPGLIWDLGQQLGDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSGSYGRLGPSEPRGIYASERPKSLGDASPSVPETVGARAAVPRSFSAPYPTAAGSAGPEACSSAERRARAGPFLTPSPLHAVALRSPRPCCRPPQDSPDASGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPPPGGARSAPEPPVERAGVRPASPAPLGRAWASPWEAEATPEPVAPPAVPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKAPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKAARSQSETSLLGRAAAVPPGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRGRPRGPAARGPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPASGVGGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGPGAGAGGGAPAGPAKVFVKIKASHALKKKILRFRSGSLKVMTTV", "length": 632, "header": "tr|E1BG86-1|E1BG86_BOVIN Isoform 1 of Dishevelled binding antagonist of beta catenin 3 OS=Bos taurus OX=9913 GN=DACT3 PE=3 SV=4 CANONICAL=E1BG86-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MSL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BG86/entry#A0A3Q1MSL1-1", "sequence": { "sequence": "MIRAFSFPVSPERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGAEAEDEEDADEDEDAAAARRAAAALEEQLEALPGLIWDLGQQLGDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSGSYGRLGPSEPRGIYASERPKSLGKVGGVGPLEP", "length": 177, "header": "tr|A0A3Q1MSL1-1|E1BG86_BOVIN Computationally mapped isoform of Dishevelled binding antagonist of beta catenin 3 OS=Bos taurus OX=9913 GN=DACT3 PE=3 SV=2 CANONICAL=E1BG86-1" }, "locus": { "chromosome": "18", "start_pos": 53783985, "end_pos": 53777707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083182.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083182.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073074.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073074.2" } ] } }, { "isoform_ac": "E1BG86-1", "url": "https://www.uniprot.org/uniprotkb/E1BG86/entry#E1BG86-1", "sequence": { "sequence": "MIRAFSFPVSPERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGAEAEDEEDADEDEDAAAARRAAAALEEQLEALPGLIWDLGQQLGDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSGSYGRLGPSEPRGIYASERPKSLGDASPSVPETVGARAAVPRSFSAPYPTAAGSAGPEACSSAERRARAGPFLTPSPLHAVALRSPRPCCRPPQDSPDASGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPPPGGARSAPEPPVERAGVRPASPAPLGRAWASPWEAEATPEPVAPPAVPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKAPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKAARSQSETSLLGRAAAVPPGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRGRPRGPAARGPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPASGVGGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGPGAGAGGGAPAGPAKVFVKIKASHALKKKILRFRSGSLKVMTTV", "length": 632, "header": "tr|E1BG86-1|E1BG86_BOVIN Isoform 1 of Dishevelled binding antagonist of beta catenin 3 OS=Bos taurus OX=9913 GN=DACT3 PE=3 SV=4 CANONICAL=E1BG86-1" }, "locus": { "chromosome": "18", "start_pos": 53783985, "end_pos": 53775049, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043415.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043415.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051010.4", "url": "https://www.ensembl.org/id/ENSBTAP00000051010.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 193, "start_aa": "Thr", "end_pos": 193, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr193", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BG86", "url": "https://www.uniprot.org/uniprotkb/E1BG86" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BG86", "url": "https://www.uniprot.org/uniprotkb/E1BG86" } ], "pmid": "" }, { "name": "protein kinase C binding", "id": "GO:0005080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005080", "evidence": [ { "database": "UniProtKB", "id": "E1BG86", "url": "https://www.uniprot.org/uniprotkb/E1BG86" } ], "pmid": "" }, { "name": "protein kinase A binding", "id": "GO:0051018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051018", "evidence": [ { "database": "UniProtKB", "id": "E1BG86", "url": "https://www.uniprot.org/uniprotkb/E1BG86" } ], "pmid": "" }, { "name": "delta-catenin binding", "id": "GO:0070097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070097", "evidence": [ { "database": "UniProtKB", "id": "E1BG86", "url": "https://www.uniprot.org/uniprotkb/E1BG86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "E1BG86", "url": "https://www.uniprot.org/uniprotkb/E1BG86" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "E1BG86", "url": "https://www.uniprot.org/uniprotkb/E1BG86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BG86-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 632, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BG86-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BG86" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 193 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 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Suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. Upon binding to its ligands PVR/CD155 or NECTIN2/CD112, which are expressed on antigen-presenting cells, sends inhibitory signals to the T-cell or NK cell. Mechanistically, interaction with ligand leads to phosphorylation of the cytoplasmic tail by Src family tyrosine kinases such as FYN or LCK, allowing subsequent binding to adapter GRB2 and SHIP1/INPP5D. In turn, inhibits PI3K and MAPK signaling cascades. In addition, associates with beta-arrestin-2/ARRB2 to recruit SHIP1/INPP5D that suppresses autoubiquitination of TRAF6 and subsequently inhibits NF-kappa-B signaling pathway. 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"Protein" ] } ], "sequence": { "sequence": "MQWCLLLIWAQVLKQALLPTSGAVTGRIVTMGNISAEEGGSVTLQCHLSSTTAKVTQVNWNLQDQVVAIHHDSLGWHINPAFKERVVPDSNLGLTLRWLTSNDTGQYTCVYHTYPDGIYKGVLFLQVLRHSVAEYSAGFQIPLLGAMAAVLVVICIAVIAVATLARKKSLRIRSAEGDLGRGPSEPEACRPRVVSSPGSCVQADAGLCDDQGSEDHAEAEPHEYFNVLSYRSLASFSFPTETG", "length": 243, "header": "tr|E1BF67-1|E1BF67_BOVIN Isoform 1 of T-cell immunoreceptor with Ig and ITIM domains OS=Bos taurus OX=9913 GN=TIGIT PE=4 SV=2 CANONICAL=E1BF67-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MTE6-1", "url": "https://www.uniprot.org/uniprotkb/E1BF67/entry#A0A3Q1MTE6-1", "sequence": { "sequence": "MKDLGLWGTCLADPKKEAGGAVTGRIVTMGNISAEEGGSVTLQCHLSSTTAKVTQVNWNLQDQVVAIHHDSLGWHINPAFKERVVPDSNLGLTLRWLTSNDTGQYTCVYHTYPDGIYKGVLFLQVLRHSVAEYSAGFQIPLLGAMAAVLVVICIAVIAVATLARKKSLRIRSAEGDLGRGPSEPEACRPRVVSSPGSCVQADAGLCDDQGSEDHAEAEPHEYFNVLSYRSLASFSFPTETG", "length": 241, "header": "tr|A0A3Q1MTE6-1|E1BF67_BOVIN Computationally mapped isoform of T-cell immunoreceptor with Ig and ITIM domains OS=Bos taurus OX=9913 GN=TIGIT PE=4 SV=1 CANONICAL=E1BF67-1" }, "locus": { "chromosome": "1", "start_pos": 58943035, "end_pos": 58927149, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082520.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082520.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057906.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057906.1" } ] } }, { "isoform_ac": "E1BF67-1", "url": "https://www.uniprot.org/uniprotkb/E1BF67/entry#E1BF67-1", "sequence": { "sequence": "MQWCLLLIWAQVLKQALLPTSGAVTGRIVTMGNISAEEGGSVTLQCHLSSTTAKVTQVNWNLQDQVVAIHHDSLGWHINPAFKERVVPDSNLGLTLRWLTSNDTGQYTCVYHTYPDGIYKGVLFLQVLRHSVAEYSAGFQIPLLGAMAAVLVVICIAVIAVATLARKKSLRIRSAEGDLGRGPSEPEACRPRVVSSPGSCVQADAGLCDDQGSEDHAEAEPHEYFNVLSYRSLASFSFPTETG", "length": 243, "header": "tr|E1BF67-1|E1BF67_BOVIN Isoform 1 of T-cell immunoreceptor with Ig and ITIM domains OS=Bos taurus OX=9913 GN=TIGIT PE=4 SV=2 CANONICAL=E1BF67-1" }, "locus": { "chromosome": "1", "start_pos": 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"MHGWMLLVWVQGLTETAFLAAGATAGTMETKGNISAEEGGSVVLQCHFSSDTAEVTQVNWEQRDQLLAVYSVDLGWYVPSVFSDRVVPGPSLGLTFQSLTTNDTGEYFCTYHTYPDGIYKGRIFLKVQESSAHFQIALPGGTMAAVLGLICLMATGVTVLARKKSIRMHSVESGLGRTEAEPQEWNLRILLSPSGPVQTQAAPADLCGEQTEDDYTDPQDYFNVLSYRSLESFIALSKTGQ", "length": 241 }, "evidence": [ { "id": "E1BF67", "url": "https://omabrowser.org/oma/group/E1BF67/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P86176-1", "protein_name": "T-cell immunoreceptor with Ig and ITIM domains", "gene_name": "Tigit", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHGWLLLVWVQGLIQAAFLATAIGATAGTIDTKRNISAEEGGSVILQCHFSSDTAEVTQVDWKQQDQLLAIYSVDLGWHVASVFSDRVVPGPSLGLTFQSLTMNDTGEYFCTYHTYPGGIYKGRIFLKVQESSDDRNGLAQFQTAPLGGTMAAVLGLICLMVTGVTVLARKDKSIRMHSIESGLGRTEAEPQEWNLRSLSSPGSPVQTQTAPAGPCGEQAEDDYADPQEYFNVLSYRSLESFIAVSKTG", "length": 249 }, "evidence": [ { "id": "E1BF67", "url": "https://omabrowser.org/oma/group/E1BF67/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q495A1-1", "protein_name": "T-cell immunoreceptor with Ig and ITIM domains", "gene_name": "TIGIT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIPLLGAMAATLVVICTAVIVVVALTRKKKALRIHSVEGDLRRKSAGQEEWSPSAPSPPGSCVQAEAAPAGLCGEQRGEDCAELHDYFNVLSYRSLGNCSFFTETG", "length": 244 }, "evidence": [ { "id": "E1BF67", "url": "https://omabrowser.org/oma/group/E1BF67/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "E1BF67", "url": "https://www.uniprot.org/uniprotkb/E1BF67" } ], "pmid": "" 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"pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of T cell activation", "id": "GO:0050868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050868", "evidence": [ { "database": "UniProtKB", "id": "E1BF67", "url": "https://www.uniprot.org/uniprotkb/E1BF67" } ], "pmid": "" }, { "name": "negative regulation of interleukin-12 production", "id": "GO:0032695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032695", "evidence": [ { "database": "UniProtKB", "id": "E1BF67", "url": "https://www.uniprot.org/uniprotkb/E1BF67" } ], "pmid": "" }, { "name": "negative regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045953", "evidence": [ { "database": "UniProtKB", "id": "E1BF67", "url": "https://www.uniprot.org/uniprotkb/E1BF67" } ], "pmid": "" }, { "name": "positive regulation of interleukin-10 production", "id": "GO:0032733", "url": 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"tr|E1BJ63-1|E1BJ63_BOVIN Isoform 1 of SIM bHLH transcription factor 2 OS=Bos taurus OX=9913 GN=SIM2 PE=4 SV=4 CANONICAL=E1BJ63-1" }, "locus": { "chromosome": "1", "start_pos": 149024426, "end_pos": 148973439, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028592.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028592.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028592.7", "url": "https://www.ensembl.org/id/ENSBTAP00000028592.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 622, "start_aa": "Thr", "end_pos": 622, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr622", "evidence": [ { "id": "", "database": "GlyGen", "url": 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"" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "E1BJ63", "url": "https://www.uniprot.org/uniprotkb/E1BJ63" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BJ63", "url": "https://www.uniprot.org/uniprotkb/E1BJ63" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "E1BJ63", "url": "https://www.uniprot.org/uniprotkb/E1BJ63" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": 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"url_external": "https://alphafold.ebi.ac.uk/entry/E1BJ63" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ63" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 53, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ63" }, { "id": "PS50112", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50112" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PAS", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 149, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ63" }, { "id": "PS51302", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51302" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Single-minded C-terminal", "eco_id": "ECO_0000259", "start_pos": 336, "end_pos": 670, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 622 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFC3-1", "uniprot_ac": "E1BFC3", "uniprot_id": "E1BFC3_BOVIN", "mass": { "chemical_mass": 54888.0, "monoisotopic_mass": 54888.0 }, "refseq": { "ac": "NP_001180041", "name": "gasdermin-E", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180041" }, "gene_names": [ { "name": "GSDME", "type": "recommended", "evidence": [ { "id": "E1BFC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ] }, { "name": "DFNA5", "type": "synonym", "evidence": [ { "id": "NP_001180041", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180041" } ] }, { "name": "GSDME", "type": "synonym", "evidence": [ { "id": "NP_001180041", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180041" } ] } ], "protein_names": [ { "name": "DFNA5, deafness associated tumor suppressor", "type": "synonym", "evidence": [ { "id": "NP_001180041", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180041" } ] }, { "name": "Gasdermin E", "type": "synonym", "evidence": [ { "id": "E1BFC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFC3/entry#names_and_taxonomy" } ] }, { "name": "gasdermin-E", "type": "synonym", "evidence": [ { "id": "NP_001180041", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180041" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GSDME", "url": "https://www.uniprot.org/uniprotkb/E1BFC3", "locus": { "chromosome": "4", "start_pos": 71162654, "end_pos": 71088549, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015326", "url": "https://www.ensembl.org/id/ENSBTAG00000015326" } ] } } ], "crossref": [ { "id": "E1BFC3", "url": "https://alphafold.ebi.ac.uk/entry/E1BFC3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015326", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015326", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "616398", "url": "https://www.ncbi.nlm.nih.gov/gene/616398", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616398", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616398", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EMTNDCL", "url": "https://omabrowser.org/oma/group/EMTNDCL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFC3", "url": "https://www.orthodb.org/?gene=E1BFC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15207:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15207:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17708", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17708", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-111457", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111457", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-111458", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111458", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-111461", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111461", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5620971", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620971", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5686938", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5686938", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001180041", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180041", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1NFS3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NFS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6D0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6D0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFC3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFAKATRNFLKEVDAGGNLIAVSNLNDSDKLQLLSLVTKKKRYWCWQRPKYQFLSVTLGDVLTEDQFLSPVVVESDFVKYEGKFENHVSGTLETALGKVKLNIGGKGLVESQSSFGTLRKQEVDLQQLIGDAQERTINLKNPVLQQVLERKNAVLCVLTQKIVTTQKCVISEHVQIEETCGGMVGIQTRTVQVSAMEDGNIIKDTNVVLEIPAPTTIAYGVIELYVRADGQFEFCLLQGKHGGFEQERRSNSVLLDPLPFREFVFWDMPDAGQGLPAQDKPLSVLKQATLLLERNFHPFMELPEQQQIALNDVLQAVLLDEELLVVLEQVCDDIVSSLSPSLVALGELKPSQKHNLTTFLRLVGCSVQGERLGSQDVVDNQKLFSTAFFLVSALAEMPDNAAALLGTCCKLQIIPLLYHLLRALSHDGVSDLEDPALAPLKDREKFGIVQRLFAATDINLERMQSSVKAASREDPNVLPLILYISLSGLCALGRAQ", "length": 496, "header": "tr|E1BFC3-1|E1BFC3_BOVIN Isoform 1 of Gasdermin E OS=Bos taurus OX=9913 GN=GSDME PE=3 SV=1 CANONICAL=E1BFC3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NFS3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFC3/entry#A0A3Q1NFS3-1", "sequence": { "sequence": "MFAKATRNFLKEVDAGGNLIAVSNLNDSDKLQLLSLVTKKKRYWCWQRPKYQFLSVTLGDVLTEDQFLSPVVVESDFVKYEGKFENHVSGTLETALGKVKLNIGGKGLVESQSSFGTLRKQEVDLQQLIGDAQERTINLKNPVLQQVLERKNAVLCVLTQKIVTTQKCVISEHVQIEETCGGMVGIQTRTVQVSAMEDGNIIKDTNVVLEIPAPTTIAYGVIELYVRADGQFEFCLLQGKHGGFEQERRSNSVLLDPLPFREFVFWDMPDAGQGLPAQDKPLSVLKQATLLLERNFHPFMELPEQQQIALNDVLQAVLLDEELLVVLEQVCDDIVSSLSPSLVALGELKPSQKHNLTTFLRLVGCSVQGERLGSQDVVDNQKLFSTAFFLVSALAEMPDNAAALLGTCCKLQIIPLLYHLQRPVETAARHHSKKQFRCHSQLKAEPHHPEECCVLVL", "length": 457, "header": "tr|A0A3Q1NFS3-1|E1BFC3_BOVIN Computationally mapped isoform of Gasdermin E OS=Bos taurus OX=9913 GN=GSDME PE=3 SV=1 CANONICAL=E1BFC3-1" }, "locus": { "chromosome": "4", "start_pos": 71158513, "end_pos": 71097088, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080428.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080428.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070549.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070549.2" } ] } }, { "isoform_ac": "A0AAA9S6D0-1", "url": "https://www.uniprot.org/uniprotkb/E1BFC3/entry#A0AAA9S6D0-1", "sequence": { "sequence": "MFAKATRNFLKEVDAGGNLIAVSNLNDSDKLQLLSLVTKKKRYWCWQRPKYQFLSVTLGDVLTEDQFLSPVVVESDFVKYEGKFENHVSGTLETALGKVKLNIGGKGLVESQSSFGTLRKQEVDLQQLIGDAQERTINLKNPVLQQVLERKNAVLCVLTQKIVTTQKCVISEHVQIEETCGGMVGIQTRTVQVSAMEDGNIIKDTNVVLEIPAPTTIAYGVIELYVRADGQFEFCLLQGKHGGFEQERRSNSVLLDPLPFREFVFWDMPDAGQGLPAQDKPLSVLKQATLLLERNFHPFMELPEQQQIALNDVLQAVLLDEELLVVLEQVVRLETPRGNVSAYFSGVSRDKRPARVKSCL", "length": 360, "header": "tr|A0AAA9S6D0-1|E1BFC3_BOVIN Computationally mapped isoform of Gasdermin E OS=Bos taurus OX=9913 GN=GSDME PE=3 SV=1 CANONICAL=E1BFC3-1" }, "locus": { "chromosome": "4", "start_pos": 71150268, "end_pos": 71097088, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130718.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130718.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081530.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081530.1" } ] } }, { "isoform_ac": "E1BFC3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFC3/entry#E1BFC3-1", "sequence": { "sequence": "MFAKATRNFLKEVDAGGNLIAVSNLNDSDKLQLLSLVTKKKRYWCWQRPKYQFLSVTLGDVLTEDQFLSPVVVESDFVKYEGKFENHVSGTLETALGKVKLNIGGKGLVESQSSFGTLRKQEVDLQQLIGDAQERTINLKNPVLQQVLERKNAVLCVLTQKIVTTQKCVISEHVQIEETCGGMVGIQTRTVQVSAMEDGNIIKDTNVVLEIPAPTTIAYGVIELYVRADGQFEFCLLQGKHGGFEQERRSNSVLLDPLPFREFVFWDMPDAGQGLPAQDKPLSVLKQATLLLERNFHPFMELPEQQQIALNDVLQAVLLDEELLVVLEQVCDDIVSSLSPSLVALGELKPSQKHNLTTFLRLVGCSVQGERLGSQDVVDNQKLFSTAFFLVSALAEMPDNAAALLGTCCKLQIIPLLYHLLRALSHDGVSDLEDPALAPLKDREKFGIVQRLFAATDINLERMQSSVKAASREDPNVLPLILYISLSGLCALGRAQ", "length": 496, "header": "tr|E1BFC3-1|E1BFC3_BOVIN Isoform 1 of Gasdermin E OS=Bos taurus OX=9913 GN=GSDME PE=3 SV=1 CANONICAL=E1BFC3-1" }, "locus": { "chromosome": "4", "start_pos": 71162191, "end_pos": 71097088, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020371.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020371.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020371.4", "url": "https://www.ensembl.org/id/ENSBTAP00000020371.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616398", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616398", "resource": "KEGG Pathway" }, { "id": "R-BTA-111457", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111457", "resource": "Reactome", "description": "Release of apoptotic factors from the mitochondria" }, { "id": "R-BTA-111458", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111458", "resource": "Reactome", "description": "Formation of apoptosome" }, { "id": "R-BTA-111461", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111461", "resource": "Reactome", "description": "Cytochrome c-mediated apoptotic response" }, { "id": "R-BTA-5620971", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620971", "resource": "Reactome", "description": "Pyroptosis" }, { "id": "R-BTA-5686938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5686938", "resource": "Reactome", "description": "Regulation of TLR by endogenous ligand" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XFB5-1", "protein_name": "DFNA5, deafness associated tumor suppressor", "gene_name": "DFNA5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFAKATRNFVRETDSGGDLIPVSHLNASDKLQLLSLVTKRKKFWCWQKPKYHFLAVSLSDVLTEDKPIKPVIVESDFAKYMGKFEDVVQGSIETSFGKISLGAGAKGCVESQSSFGSLRKQEVDLQQLMKDVKDRMINLNSSLLQQVIERKREVLCILREKIITTQRCTISEHIQTEEKVSGLLGCTTKIVKVSVSDSGSMMKDSSVILEIPPATTIAYGVIELFIKCDGQFEFCLLNEQQGGFERENAEGSTSPHSVLFRDTSFLFHPDAVDNGMYSGAENPVPSHASLSVLKKDLSQLKAQFQPFVKLPEDKQRALYKSLCELLLHEETLTALEDVLDALCTGDKPDLKELKPAQQQDLADFLQLVGCRVQDELLLQNYHLQDEELLSAAHLLISAISELSDYTLVLLRACSDLQVVPALCCLPYIASADGTLALSSPSVATLTDRRRFDVAQRLFASANINLEKTETSVKAVTMREPRFFPLVLYVALCGLHSLGGTVEELF", "length": 505 }, "evidence": [ { "id": "E1BFC3", "url": "https://omabrowser.org/oma/group/E1BFC3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MAG0-1", "protein_name": "Gasdermin E", "gene_name": "Gsdme", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKATRNFLKEVDAGGDLISVSHLNDSDKLQLLSLVTKKKRYWCWQRPKYQFLSATLGDVLTEGHCLSPVVVESDFVKYESKCENHKSGTIGTVMGKVKLNVGGKGLVESQSSFGTLRKQEVDVQQLIQDAVGRTVNLDSLVLQQVLESRNEVLCVLTQKIVTTQKCVISEHVQSEETCGGMVGIQTKIVQVSAMEDGTITTDTNVMLEIPAATTIAYGIMELYVKKDGQFEFCLLQGKHGGFEQERKVDSVYLDPLAYREFAFLDMPDGGQGISSQDGPLRVLKQATLHLERSFRSFAVLPAQQQMALFCILQKILFDEELLRALEQVCDDVAGGLWSSQAILAMEELTGSQQQDLTAFLKLVGYRVQGEHPGPQDEVSNQKLFATAYFLVSALAEMPDNATVFLGTCCKLHVIPSLCHLLHALSDDSVCDFQDPTLAPLRDTERFGIVQRLFASADIALERMQFSAKATILKDSCMFPLILHITLSGLYTLSKEHEEHLFQSEVHATSQD", "length": 513 }, "evidence": [ { "id": "E1BFC3", "url": "https://omabrowser.org/oma/group/E1BFC3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1ST94-1", "protein_name": "Gasdermin E", "gene_name": "GSDME", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFAKATKNFLREVDTGGNLTAVSNLNDSDKLQLLSLVTKKRRFWCWQKPKYQFLSVTLGDVLTEDQILSPVVVESDFVKYEGRFENHTRGALKTALGKAKLTLGGKGFVESQSSFGTLRKQEVDLQQLIRDAQGRTIDLKNPVLQQVLERKNEVLCVLTQKIVTTQQCVISEHVQMEKCGVVGIQLKTVQVSVMDRGNISKGSNVVLEIPAPTTLAYGVIELYLRVDGQFEFCLLQEKHGGFQQTRESSCASLEPLPLLELGFWDMTDALQGASVVDEPLGVLKQVTWLLKRNVHPFAELPEPQQTALNDVLQEVLFDEEMLVVLEQVCDSVASSRLLPPLAGLGELKPSQQQQLMAFLQLAGCSVQGGVPDPEDVVSNRKLFSTAYLLVSALAEMPDNAAVLLGTCCKLQIIPTLCHLLYALSDEGMSDLEDPMLAPLKDAETLEIVQHLFALADINLEMLQSSVQATASKDPAVLPLILYISLNGLCALGRAH", "length": 495 }, "evidence": [ { "id": "E1BFC3", "url": "https://omabrowser.org/oma/group/E1BFC3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O60443-1", "protein_name": "Gasdermin-E", "gene_name": "GSDME", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFWCWQRPKYQFLSLTLGDVLIEDQFPSPVVVESDFVKYEGKFANHVSGTLETALGKVKLNLGGSSRVESQSSFGTLRKQEVDLQQLIRDSAERTINLRNPVLQQVLEGRNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELYVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSVLKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAVLGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKSSVKAVILKDSKVFPLLLCITLNGLCALGREHS", "length": 496 }, "evidence": [ { "id": "E1BFC3", "url": "https://omabrowser.org/oma/group/E1BFC3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2D3-1", "protein_name": "Gasdermin-E", "gene_name": "Gsdme", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAKATRNFLKEVDAGGDLISVSHLNDSDKLQLLSLVTKKKRYWCWQRPKYQILSATLEDVLTEGHCLSPVVVESDFVKYESKCENHKSGAIGTVVGKVKLNVGGKGVVESHSSFGTLRKQEVDVQQLIQDAVKRTVNMDNLVLQQVLESRNEVLCVLTQKIMTTQKCVISEHVQSEETCGGMVGIQTKTIQVSATEDGTVTTDTNVVLEIPAATTIAYGIMELFVKQDGQFEFCLLQGKHGGFEHERKLDSVYLDPLAYREFAFLDMLDGGQGISSQDGPLRVVKQATLHLERSFHPFAVLPAQQQRALFCVLQKILFDEELLRALEQVCDDVAGGLWSSQAVLAMEELTDSQQQDLTAFLQLVGYRIQGEHPGPQDEVSNQKLFATAYFLVSALAEMPDNATVFLGTCCKLHVISSLCCLLHALSDDSVCDFHNPTLAPLRDTERFGIVQRLFASADIALERMQFSAKATILKDSCIFPLILHITLSGLSTLSKEHEEELCQSGHATGQD", "length": 512 }, "evidence": [ { "id": "E1BFC3", "url": "https://omabrowser.org/oma/group/E1BFC3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "programmed cell death", "id": "GO:0012501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012501", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "positive regulation of intrinsic apoptotic signaling pathway", "id": "GO:2001244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001244", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "positive regulation of immune response to tumor cell", "id": "GO:0002839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002839", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "pyroptotic cell death", "id": "GO:0141201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141201", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "wide pore channel activity", "id": "GO:0022829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022829", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" }, { "name": "cardiolipin binding", "id": "GO:1901612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901612", "evidence": [ { "database": "UniProtKB", "id": "E1BFC3", "url": "https://www.uniprot.org/uniprotkb/E1BFC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFC3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 496, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFC3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFC3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 }, { "start_pos": 355, "end_pos": 357 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKX9-1", "uniprot_ac": "E1BKX9", "uniprot_id": "E1BKX9_BOVIN", "mass": { "chemical_mass": 107236.0, "monoisotopic_mass": 107236.0 }, "refseq": { "ac": "XP_024844263", "name": "cyclin-dependent kinase-like 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844263" }, "gene_names": [ { "name": "CDKL5", "type": "recommended", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "name": "CDKL5", "type": "synonym", "evidence": [ { "id": "XP_024844263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844263" } ] } ], "protein_names": [ { "name": "Cyclin-dependent kinase-like 5", "type": "recommended", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.22", "type": "synonym", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9/entry#names_and_taxonomy" } ] }, { "name": "cyclin-dependent kinase-like 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024844263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844263" } ] } ], "function": [ { "annotation": "Mediates phosphorylation of MECP2. May regulate ciliogenesis.", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9#function" }, { "database": "UniProtKB", "id": "ARBA00053703", "url": "https://www.uniprot.org/uniprotkb/ARBA00053703#function" }, { "database": "UniProtKB", "id": "A0A3Q1NMR6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMR6#function" }, { "database": "UniProtKB", "id": "A0AAA9SW06", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW06#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CDKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKX9", "locus": { "chromosome": "X", "start_pos": 124822426, "end_pos": 124995607, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007428", "url": "https://www.ensembl.org/id/ENSBTAG00000007428" } ] } } ], "crossref": [ { "id": "E1BKX9", "url": "https://alphafold.ebi.ac.uk/entry/E1BKX9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007428", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007428", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07848", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07848", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538337", "url": "https://www.ncbi.nlm.nih.gov/gene/538337", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538337", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538337", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MQHARTS", "url": "https://omabrowser.org/oma/group/MQHARTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKX9", "url": "https://www.orthodb.org/?gene=E1BKX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF111", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF111", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024844263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844263", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1NMR6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NMR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SW06", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SW06-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKX9-1", "url": "https://www.uniprot.org/uniprotkb/E1BKX9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSAKRKPYHVESSTLSNRNQASKSAALQSHHRSNSKDIQNLGVGLPRADEGLPANESFLNGNLAGATLSPMHTKTYQAGSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSDGPGTKYLKSSSRSQQNRHSFMESSQSKAGTLQPGEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQIAESSTSRYFPSSCLDLNSPTSPTPTRHGDTRTLLSPSGRNNRSEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARSSVKESSREGTSSFHVRQKSEGGAYHDPHSDDGAAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFFRSMKKKKKKSQTVPNSDGPDLLTLQKAIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRFQPLTTQQAKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPALQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL", "length": 960, "header": "tr|E1BKX9-1|E1BKX9_BOVIN Isoform 1 of Cyclin-dependent kinase-like 5 OS=Bos taurus OX=9913 GN=CDKL5 PE=3 SV=3 CANONICAL=E1BKX9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NMR6-1", "url": "https://www.uniprot.org/uniprotkb/E1BKX9/entry#A0A3Q1NMR6-1", "sequence": { "sequence": "MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSAKRKPYHVESSTLSNRNQASKSAALQSHHRSNSKDIQNLGVGLPRADEGLPANESFLNGNLAGATLSPMHTKTYQAGSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSDGPGTKYLKSSSRSQQNRHSFMESSQSKAGTLQPGEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQIAESSTSRYFPSSCLDLNSPTSPTPTRHGDTRTLLSPSGRNNRSEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARSSVKESSREGTSSFHVRQKSEGGAYHDPHSDDGAAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFFRSMKKKKKKSQTTDSTNGENPSIKKSLFPLFNSKNHLKHSSSLKKLPVVTPPMVPNSDGPDLLTLQKAIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRFQPLTTQQAKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPALQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL", "length": 1001, "header": "tr|A0A3Q1NMR6-1|E1BKX9_BOVIN Computationally mapped isoform of Cyclin-dependent kinase-like 5 OS=Bos taurus OX=9913 GN=CDKL5 PE=3 SV=1 CANONICAL=E1BKX9-1" }, "locus": { "chromosome": "X", "start_pos": 124936673, "end_pos": 124822453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076996.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076996.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073932.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073932.2" } ] } }, { "isoform_ac": "A0AAA9SW06-1", "url": "https://www.uniprot.org/uniprotkb/E1BKX9/entry#A0AAA9SW06-1", "sequence": { "sequence": "MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSAKRKPYHVESSTLSNRNQASKSAALQSHHRSNSKDIQNLGVGLPRADEGLPANESFLNGNLAGATLSPMHTKTYQAGSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSDGPGTKYLKSSSRSQQNRHSFMESSQSKAGTLQPGEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQIAESSTSRYFPSSCLDLNSPTSPTPTRHGDTRTLLSPSGRNNRSEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARSSVKESSREGTSSFHVRQKSEGGAYHDPHSDDGAAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFFRSMKKKKKKSQTVPNSDGPDLLTLQKAIHSASTPSSRPKEWRPEKISDLQTQ", "length": 832, "header": "tr|A0AAA9SW06-1|E1BKX9_BOVIN Computationally mapped isoform of Cyclin-dependent kinase-like 5 OS=Bos taurus OX=9913 GN=CDKL5 PE=3 SV=1 CANONICAL=E1BKX9-1" }, "locus": { "chromosome": "X", "start_pos": 124936673, "end_pos": 124824902, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135597.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135597.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088201.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088201.1" } ] } }, { "isoform_ac": "E1BKX9-1", "url": "https://www.uniprot.org/uniprotkb/E1BKX9/entry#E1BKX9-1", "sequence": { "sequence": "MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSAKRKPYHVESSTLSNRNQASKSAALQSHHRSNSKDIQNLGVGLPRADEGLPANESFLNGNLAGATLSPMHTKTYQAGSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSDGPGTKYLKSSSRSQQNRHSFMESSQSKAGTLQPGEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQIAESSTSRYFPSSCLDLNSPTSPTPTRHGDTRTLLSPSGRNNRSEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARSSVKESSREGTSSFHVRQKSEGGAYHDPHSDDGAAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFFRSMKKKKKKSQTVPNSDGPDLLTLQKAIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRFQPLTTQQAKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPALQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL", "length": 960, "header": "tr|E1BKX9-1|E1BKX9_BOVIN Isoform 1 of Cyclin-dependent kinase-like 5 OS=Bos taurus OX=9913 GN=CDKL5 PE=3 SV=3 CANONICAL=E1BKX9-1" }, "locus": { "chromosome": "X", "start_pos": 124936673, "end_pos": 124822453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009766.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009766.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009766.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009766.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 531, "start_aa": "Thr", "end_pos": 531, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr531", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:538337", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538337", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MQ42-1", "protein_name": "Cyclin-dependent kinase-like 5", "gene_name": "Cdkl5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSTKRKPYHVESSTLSNRNQSSKGAALQTHHRSNSKDIQNLSVGLPRADEGLPANESFLNGNLAGATLSPMHTKTYQASTQPGSSSKDHTNNNIPHLLSPKEAKSKTEFDFSIDPKPSEGPGTKYLKSSSRSQQNRHSFMESSQSKAGTLQPSEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQITDTNTSRYFPSSCLDLNSPTSPTPTRHSDTRTLLSPSGRNNRNEGTLDSRRTATRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARPSVKESSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSDSSSGTNHSKRQPGFDPWKSPENISHSDQLKEKEKQGFFRSMKKKKKKSQAVPNTDGPDLLTLQKAIHSSSTASSRPKEWRPEKLSDLQTQSQPLKSLRKLLHLSSSTNHPASSDPRFQPLTAQQTKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPALQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL", "length": 960 }, "evidence": [ { "id": "E1BKX9", "url": "https://omabrowser.org/oma/group/E1BKX9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O76039-2", "protein_name": "Cyclin-dependent kinase-like 5", "gene_name": "CDKL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSAKRKPYHVESSTLSNRNQAGKSTALQSHHRSNSKDIQNLSVGLPRADEGLPANESFLNGNLAGASLSPLHTKTYQASSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSEGPGTKYLKSNSRSQQNRHSFMESSQSKAGTLQPNEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQIAEPSTSRYFPSSCLDLNSPTSPTPTRHSDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARSSVKETSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFFRSMKKKKKKSQTVPNSDSPDLLTLQKSIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRFQPLTAQQTKNSFSEIRIHPLSQASGGSSNIRQEPAPKGRPALQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL", "length": 960 }, "evidence": [ { "id": "E1BKX9", "url": "https://omabrowser.org/oma/group/E1BKX9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UTQ8-1", "protein_name": "Cyclin-dependent kinase-like 5", "gene_name": "Cdkl5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSTKRKPYHVESSTLSNRNQSTKGAALQTHHRSNSKDIQNLSVGLPRAEEGLPANESFLNGNLAGATLSPMHTKTYQASTQPGSSSKDLTNNNIPHLLSPKEAKSKTEFDFNIDTKPSEGPGTKYLKSSTRSQQNRHSFMESSQSKAGTLQPSEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQITETNTSRYFPSSCLDLNSPTSPTPTRHTDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARPSVKESSREGASSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSDSSSGTNHSKRQPGFDPWKSPENISHADQLKEKEKQGFFRSMKKKKKKTQTVPNTDGPDLLTLQKAIHSSSTASSRPKEWRPEKLSDLQTQSQPLKSLRKLLHLSSSTNHPASSDPRFQPLTAQQAKNSFSEIRIHPLSQATGGSSNIRQEPTPKGRPALQLPGSSLLRYNGWKHSRSRSSQPDEVIFLASHEKWKQ", "length": 938 }, "evidence": [ { "id": "E1BKX9", "url": "https://omabrowser.org/oma/group/E1BKX9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" }, { "name": "ciliary tip", "id": "GO:0097542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097542", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" }, { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" }, { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "E1BKX9", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" }, { "start_pos": 731, "end_pos": 733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 764, "end_pos": 766, "annotation": "n_glycosylation_sequon" }, { "start_pos": 942, "end_pos": 944, "annotation": "n_glycosylation_sequon" }, { "start_pos": 945, "end_pos": 947, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", 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"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", 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"https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", 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"MWAGLLLRAACVALLLPGTPARGYTGRKTPGHFGAERRRLGPHVCLSGFGSGCCPGWAPSMGSGHCTLPLCSFGCGSGICIAPNVCSCQDGEQGPTCPEAHGPCGEYGCDLTCNHGGCQEVARVCPVGFSMTETAVGIRCTDIDECLSSSCEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTPCQQRCKNSIGSYRCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRLRADRVSCEAFPKAVLAPSAILQPLQHPPKMLLLLPEAGRPALSPGHSPPSGAPGPPTGVRSTRPPPPMPALSTSSPSAPTPLLSTPVATPVPHPSLLGTLRPPAQLQKTAVTPPLPRGPETTRLAPGPSACWHLEATYESGSRWTEPGCSQCWCEDGEVTCEKVTCEAACSHPIPSRDGGCCPSCTGCFHSGVIRAEGDVFSPPNQNCTVCVCLAGNVSCISPECPPDPCQASPKSDCCTCVPVRCYFHGRWYADGAVFSGGGDECTTCVCQNGEVECSFTPCPELDCPREEWWLGPGQCCYACREPVPMTGCSLDDNGVEFPVGQIWSPGDPCELCICQADGSVSCKRTDCVDSCPHPIRIPGQCCPDCSAGCTYTGRIFYNNQTFPSVLDPCLSCICLLGSVACSPVDCPITCSYPFHPDGECCPVCQDCNYEGRKVGNGQVFTLDDEPCTQCVCQLGEVTCEKVSCQQACSDRTMPRRDCCSSCPESLEESRALSPRGDVELSKAARSPRGDPEAPINCSSCPGPPEVAPQRPALQLLQLLLRMNLSNPQTLPVSPSGAQASPSPSSRPGGPRASQPPQPSLGPPIPPGASSLPPASPMAPGPPPLTPALPSSASGAHSASRRPSLPAAIPRGASALSTTGPGASETPVTVLRPRRSSPATSRLSAALVATASPGPRQPTLGTSQEEESTV", "length": 948, "header": "tr|E1BEY2-1|E1BEY2_BOVIN Isoform 1 of von Willebrand factor C and EGF domain-containing protein OS=Bos taurus OX=9913 GN=VWCE PE=4 SV=4 CANONICAL=E1BEY2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RRV1-1", "url": "https://www.uniprot.org/uniprotkb/E1BEY2/entry#A0AAA9RRV1-1", "sequence": { "sequence": "MGFSRRRLGPHVCLSGFGSGCCPGWAPSMGSGHCTLPLCSFGCGSGICIAPNVCSCQDGEQGPTCPEAHGPCGEYGCDLTCNHGGCQEVARVCPVGFSMTETAVGIRCTDIDECLSSSCEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTPCQQRCKNSIGSYRCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRLRADRVSCEAFPKAVLAPSAILQPLQHPPKMLLLLPEAGRPALSPGHSPPSGAPGPPTGVRSTRPPPPMPALSTSSPSAPTPLLSTPVATPVPHPSLLGTLRPPAQLQKTAVTPPLPRGPETTRLAPGPSACWHLEATYESGSRWTEPGCSQCWCEDGEVTCEKVTCEAACSHPIPSRDGGCCPSCTGCFHSGVIRAEGDVFSPPNQNCTVCVCLAGNVSCISPECPPDPCQASPKSDCCTCVPVRCYFHGRWYADGAVFSGGGDECTTCVCQNGEVECSFTPCPELDCPREEWWLGPGQCCYACREPVPMTGCSLDDNGVEFPVGQIWSPGDPCELCICQADGSVSCKRTDCVDSCPHPIRIPGQCCPDCSAGCTYTGRIFYNNQTFPSVLDPCLSCICLLGSVACSPVDCPITCSYPFHPDGECCPVCQDCNYEGRKVGNGQVFTLDDEPCTQCVCQLGEVTCEKVSCQQACSDRTMPRRDCCSSCPESLEESRALSPRGDVELSKAARSPRGDPEAPINCSSCPGPPEVAPQRPALQLLQLLLRMNLSNPQTLPVSPSGAQASPSPSSRPGGPRASQPPQPSLGPPIPPGASSLPPASPMAPGPPPLTPALPSSASGAHSASRRPSLPAAIPRGASALSTTGPGASETPVTVLRPRRSSPATSRLSAALVATASPGPRQPTLGTSQEEESTV", "length": 916, "header": "tr|A0AAA9RRV1-1|E1BEY2_BOVIN Computationally mapped isoform of von Willebrand factor C and EGF domain-containing protein OS=Bos taurus OX=9913 GN=VWCE PE=4 SV=1 CANONICAL=E1BEY2-1" }, "locus": { "chromosome": "29", "start_pos": 39808913, "end_pos": 39779908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131195.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131195.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074981.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074981.1" } ] } }, { "isoform_ac": "E1BEY2-1", "url": "https://www.uniprot.org/uniprotkb/E1BEY2/entry#E1BEY2-1", "sequence": { "sequence": "MWAGLLLRAACVALLLPGTPARGYTGRKTPGHFGAERRRLGPHVCLSGFGSGCCPGWAPSMGSGHCTLPLCSFGCGSGICIAPNVCSCQDGEQGPTCPEAHGPCGEYGCDLTCNHGGCQEVARVCPVGFSMTETAVGIRCTDIDECLSSSCEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTPCQQRCKNSIGSYRCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRLRADRVSCEAFPKAVLAPSAILQPLQHPPKMLLLLPEAGRPALSPGHSPPSGAPGPPTGVRSTRPPPPMPALSTSSPSAPTPLLSTPVATPVPHPSLLGTLRPPAQLQKTAVTPPLPRGPETTRLAPGPSACWHLEATYESGSRWTEPGCSQCWCEDGEVTCEKVTCEAACSHPIPSRDGGCCPSCTGCFHSGVIRAEGDVFSPPNQNCTVCVCLAGNVSCISPECPPDPCQASPKSDCCTCVPVRCYFHGRWYADGAVFSGGGDECTTCVCQNGEVECSFTPCPELDCPREEWWLGPGQCCYACREPVPMTGCSLDDNGVEFPVGQIWSPGDPCELCICQADGSVSCKRTDCVDSCPHPIRIPGQCCPDCSAGCTYTGRIFYNNQTFPSVLDPCLSCICLLGSVACSPVDCPITCSYPFHPDGECCPVCQDCNYEGRKVGNGQVFTLDDEPCTQCVCQLGEVTCEKVSCQQACSDRTMPRRDCCSSCPESLEESRALSPRGDVELSKAARSPRGDPEAPINCSSCPGPPEVAPQRPALQLLQLLLRMNLSNPQTLPVSPSGAQASPSPSSRPGGPRASQPPQPSLGPPIPPGASSLPPASPMAPGPPPLTPALPSSASGAHSASRRPSLPAAIPRGASALSTTGPGASETPVTVLRPRRSSPATSRLSAALVATASPGPRQPTLGTSQEEESTV", "length": 948, "header": "tr|E1BEY2-1|E1BEY2_BOVIN Isoform 1 of von Willebrand factor C and EGF domain-containing protein OS=Bos taurus OX=9913 GN=VWCE PE=4 SV=4 CANONICAL=E1BEY2-1" }, "locus": { "chromosome": "29", "start_pos": 39810360, "end_pos": 39779908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028738.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028738.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028738.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028738.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 366, "start_aa": "Thr", "end_pos": 366, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr366", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BEY2", "url": "https://www.uniprot.org/uniprotkb/E1BEY2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BEY2", "url": "https://www.uniprot.org/uniprotkb/E1BEY2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BEY2", "url": "https://www.uniprot.org/uniprotkb/E1BEY2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BEY2", "url": "https://www.uniprot.org/uniprotkb/E1BEY2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BEY2", "url": "https://www.uniprot.org/uniprotkb/E1BEY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "E1BEY2", "url": "https://www.uniprot.org/uniprotkb/E1BEY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEY2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 948, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEY2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEY2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEY2" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 142, "end_pos": 180, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEY2" }, { "id": "PS50184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFC", "eco_id": "ECO_0000259", "start_pos": 383, "end_pos": 440, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 366 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 461, "end_pos": 463 }, { "start_pos": 471, "end_pos": 473 }, { "start_pos": 638, "end_pos": 640 }, { "start_pos": 775, "end_pos": 777 }, { "start_pos": 802, "end_pos": 804 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJW8-1", "uniprot_ac": "E1BJW8", "uniprot_id": "E1BJW8_BOVIN", "mass": { "chemical_mass": 141617.0, "monoisotopic_mass": 141617.0 }, "refseq": {}, "gene_names": [ { "name": "AFF3", "type": "recommended", "evidence": [ { "id": "E1BJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ] } ], "protein_names": [ { "name": "ALF transcription elongation factor 3", "type": "synonym", "evidence": [ { "id": "E1BJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJW8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AFF3", "url": "https://www.uniprot.org/uniprotkb/E1BJW8", "locus": { "chromosome": "11", "start_pos": 4664770, "end_pos": 5289265, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012449", "url": "https://www.ensembl.org/id/ENSBTAG00000012449" } ] } } ], "crossref": [ { "id": "E1BJW8", "url": "https://alphafold.ebi.ac.uk/entry/E1BJW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012449", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012449", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10528:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10528:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05110", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05110", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18875", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18875", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18876", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18876", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9RS39", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RS39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RS39-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RS39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJW8-1", "url": "https://www.uniprot.org/uniprotkb/E1BJW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N772", "url": "https://www.uniprot.org/uniprotkb/F1N772", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N772-1", "url": "https://www.uniprot.org/uniprotkb/F1N772-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQTRTSSASPTLRAAARPSAGLAGSRRAPPGGRGRGAERARAARSSAAAATAATAAAALTPPTMDSFDLALLQEWDLESLWGEDILNQRNDSLVVEFQSSASRCRSVYEPDRNVLRRKERERRNQEAQQDDGAFNSSYSLFSEPYKTNKGDELSNRLQNTLGNYDEMKDFLTDRSNQSHLVGVPKPGVPQAPVTKIDEHFVADSRAQTQPASVCSTTSSTPAAVPGQQSKRGAMGWQKAGHPPSDGQQRATQQGTLRTLLGDGVGRQQPRTKQVCNVEVGLQTQDRPPAMGAKHSGNGHCVQNFPPSLASKPSLVQQKPTAYVRPMDGQDQAPDESPKLKSSAETGVHCLYRGVPATKSESARAKAKLSKFSIPKQGEESRSGETNSCVEEIIREMTWPPALAAIQPPGKVEPSKFPFPNKDSQLASSGHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQAAQRTALHALSDSAGLQPADCRASAPSSKGSSSGSSSSGSSSSSDSESSSGSDSETESSSSESEGSKPPHYSSPEAEPASSNKWQLDKWLNKVNHHKPPVLIQNESHHGPESSQYYTPVKEDTQDCGKLPDVCPPGLRDKDIKGACKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVTAAAAPPPAVPGAPAESAPAPARRSAGKKPTRRTERTSAGDSGHRPEEPVAAEALGASTGVPPEPPKPRPCGNSRTNHRKELRSAVTCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDLESEQEDYPLSKAVAAAAAAAAASGNDPRLKEAPSSISGGGPRAPVGSINARTTSDIAKELEEQFYTLVPFGRNELLSPLKDSDEVRSLWVKIDLTLLSRIPEHLPQEPGVLSAPAAKDSESAPPSHASEAPVEKTLPKSKRKRKCDNEDDYREIKKAPGERESASRLSASANSTLSANHCSMNINSLAIPINKNEKVLRSPISPLSDASKHKFSGEDLTSSSRSNSNGLFTSTSSSKKHKAESQLQSHAADLTKAAHNNSENILHKSRPQTEPWSPGSNGHRDCKRQKLIFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSPTGSVGSQGSLSNSNALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFHDLDLLMGPVTLHSSMEHLVQYSQQGLHWLRNSAHLA", "length": 1315, "header": "tr|E1BJW8-1|E1BJW8_BOVIN Isoform 1 of ALF transcription elongation factor 3 OS=Bos taurus OX=9913 GN=AFF3 PE=3 SV=4 CANONICAL=E1BJW8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RS39-1", "url": "https://www.uniprot.org/uniprotkb/E1BJW8/entry#A0AAA9RS39-1", "sequence": { "sequence": "MDSFDLALLQEWDLESLCVYEPDRNVLRRKERERRNQEAQQDDGAFNSSYSLFSEPYKTNKGDELSNRLQNTLGNYDEMKDFLTDRSNQSHLVGVPKPGVPQAPVTKIDEHFVADSRAQTQPASVCSTTSSTPAAVPGQQSKRGAMGWQKAGHPPSDGQQRASKHGHRTLDLNRSAHPENRSKNPSPSVSSPSSSSSSSSSSNSAQQGTLRTLLGDGVGRQQPRTKQVCNVEVGLQTQDRPPAMGAKHSGNGHCVQNFPPSLASKPSLVQQKPTAYVRPMDGQDQAPDESPKLKSSAETGVHCLYRGVPATKSESARAKAKLSKFSIPKQGEESRSGETNSCVEEIIREMTWPPALAAIQPPGKVEPSKFPFPNKDSQLASSGHNNPKKGDAEPESPDNGTSNTSSLGWLSPFTDKGNDALRGMLEDDLKLSSDEEENEQQAAQRTALHALSDSAGLQPADCRASAPSSKGSSSGSSSSGSSSSSDSESSSGSDSETESSSSESEGSKPPHYSSPEAEPASSNKWQLDKWLNKVNHHKPPVLIQNESHHGPESSQYYTPVKEDTQDCGKLPDVCPPGLRDKDIKGACKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVTAAAAPPPAVPGAPAESAPAPARRSAGKKPTRRTERTSAGDSGHRPEEPVAAEALGASTGVPPEPPKPRPCGNSRTNHRKELRSAVTCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDLESEQEDYPLSKAVAAAAAAAAASGNDPRLKEAPSSISGGGPRAPVGSINARTTSDIAKELEEQFYTLVPFGRNELLSPLKDSDEVRSLWVKIDLTLLSRIPEHLPQEPGVLSAPAAKDSESAPPSHASEAPVEKTLPKSKRKRKCDNEDDYREIKKAPGERESASRLSASANSTLSANHCSMNINSLAIPINKNEKVLRSPISPLSDASKHKFSGEDLTSSSRSNSNGLFTSTSSSKKHKAESQLQSHAADLTKAAHNNSENILHKSRPQTEPWSPGSNGHRDCKRQKLIFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSPTGSVGSQGSLSNSNALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFHDLDLLMGPVTLHSSMEHLVQYSQQGLHWLRNSAHLA", "length": 1287, "header": "tr|A0AAA9RS39-1|E1BJW8_BOVIN Computationally mapped isoform of ALF transcription elongation factor 3 OS=Bos taurus OX=9913 GN=AFF3 PE=3 SV=1 CANONICAL=E1BJW8-1" }, "locus": { "chromosome": "11", "start_pos": 5243413, "end_pos": 4665774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091994.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091994.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075199.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075199.1" } ] } }, { "isoform_ac": "E1BJW8-1", "url": "https://www.uniprot.org/uniprotkb/E1BJW8/entry#E1BJW8-1", "sequence": { "sequence": "MRQTRTSSASPTLRAAARPSAGLAGSRRAPPGGRGRGAERARAARSSAAAATAATAAAALTPPTMDSFDLALLQEWDLESLWGEDILNQRNDSLVVEFQSSASRCRSVYEPDRNVLRRKERERRNQEAQQDDGAFNSSYSLFSEPYKTNKGDELSNRLQNTLGNYDEMKDFLTDRSNQSHLVGVPKPGVPQAPVTKIDEHFVADSRAQTQPASVCSTTSSTPAAVPGQQSKRGAMGWQKAGHPPSDGQQRATQQGTLRTLLGDGVGRQQPRTKQVCNVEVGLQTQDRPPAMGAKHSGNGHCVQNFPPSLASKPSLVQQKPTAYVRPMDGQDQAPDESPKLKSSAETGVHCLYRGVPATKSESARAKAKLSKFSIPKQGEESRSGETNSCVEEIIREMTWPPALAAIQPPGKVEPSKFPFPNKDSQLASSGHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQAAQRTALHALSDSAGLQPADCRASAPSSKGSSSGSSSSGSSSSSDSESSSGSDSETESSSSESEGSKPPHYSSPEAEPASSNKWQLDKWLNKVNHHKPPVLIQNESHHGPESSQYYTPVKEDTQDCGKLPDVCPPGLRDKDIKGACKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVTAAAAPPPAVPGAPAESAPAPARRSAGKKPTRRTERTSAGDSGHRPEEPVAAEALGASTGVPPEPPKPRPCGNSRTNHRKELRSAVTCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDLESEQEDYPLSKAVAAAAAAAAASGNDPRLKEAPSSISGGGPRAPVGSINARTTSDIAKELEEQFYTLVPFGRNELLSPLKDSDEVRSLWVKIDLTLLSRIPEHLPQEPGVLSAPAAKDSESAPPSHASEAPVEKTLPKSKRKRKCDNEDDYREIKKAPGERESASRLSASANSTLSANHCSMNINSLAIPINKNEKVLRSPISPLSDASKHKFSGEDLTSSSRSNSNGLFTSTSSSKKHKAESQLQSHAADLTKAAHNNSENILHKSRPQTEPWSPGSNGHRDCKRQKLIFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSPTGSVGSQGSLSNSNALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFHDLDLLMGPVTLHSSMEHLVQYSQQGLHWLRNSAHLA", "length": 1315, "header": "tr|E1BJW8-1|E1BJW8_BOVIN Isoform 1 of ALF transcription elongation factor 3 OS=Bos taurus OX=9913 GN=AFF3 PE=3 SV=4 CANONICAL=E1BJW8-1" }, "locus": { "chromosome": "11", "start_pos": 5244113, "end_pos": 4665774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016523.7", "url": "https://www.ensembl.org/id/ENSBTAT00000016523.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016523.7", "url": "https://www.ensembl.org/id/ENSBTAP00000016523.7" } ] } }, { "isoform_ac": "F1N772-1", "url": "https://www.uniprot.org/uniprotkb/E1BJW8/entry#F1N772-1", "sequence": { "sequence": "MDSFDLALLQEWDLESLWGEDILNQRNDSLVVEFQSSASRCRSVYEPDRNVLRRKERERRNQEAQQDDGAFNSSYSLFSEPYKTNKGDELSNRLQNTLGNYDEMKDFLTDRSNQSHLVGVPKPGVPQAPVTKIDEHFVADSRAQTQPASVCSTTSSTPAAVPGQQSKRGAMGWQKAGHPPSDGQQRATQQGTLRTLLGDGVGRQQPRTKQVCNVEVGLQTQDRPPAMGAKHSGNGHCVQNFPPSLASKPSLVQQKPTAYVRPMDGQDQAPDESPKLKSSAETGVHCLYRGVPATKSESARAKAKLSKFSIPKQGEESRSGETNSCVEEIIREMTWPPALAAIQPPGKVEPSKFPFPNKDSQLASSGHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQAAQRTALHALSDSAGLQPADCRASAPSSKGSSSGSSSSGSSSSSDSESSSGSDSETESSSSESEGSKPPHYSSPEAEPASSNKWQLDKWLNKVNHHKPPVLIQNESHHGPESSQYYTPVKEDTQDCGKLPDVCPPGLRDKDIKGACKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVTAAAAPPPAVPGAPAESAPAPARRSAGKKPTRRTERTSAGDSGHRPEEPVAAEALGASTGVPPEPPKPRPCGNSRTNHRKELRSAVTCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDLESEQEDYPLSKAVAAAAAAAAASGNDPRLKEAPSSISGGGPRAPVGSINARTTSDIAKELEEQFYTLVPFGRNELLSPLKDSDEVRSLWVKIDLTLLSRIPEHLPQEPGVLSAPAAKDSESAPPSHASEAPVEKTLPKSKRKRKCDNEDDYREIKKAPGERESASRLSASANSTLSANHCSMNINSLAIPINKNEKVLRSPISPLSDASKHKFSGEDLTSSSRSNSNGLFTSTSSSKKHKAESQLQSHAADLTKAAHNNSENILHKSRPQTEPWSPGSNGHRDCKRQKLIFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSPTGSVGSQGSLSNSNALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFHDLDLLMGPVTLHSSMEHLVQYSQQGLHWLRNSAHLA", "length": 1251, "header": "tr|F1N772-1|E1BJW8_BOVIN Computationally mapped isoform of ALF transcription elongation factor 3 OS=Bos taurus OX=9913 GN=AFF3 PE=3 SV=4 CANONICAL=E1BJW8-1" }, "locus": { "chromosome": "11", "start_pos": 5243413, "end_pos": 4665774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061254.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061254.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053656.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053656.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1143, "start_aa": "Thr", "end_pos": 1143, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1143", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 647, "start_aa": "Thr", "end_pos": 647, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr647", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "pmid": "" }, { "name": "super elongation complex", "id": "GO:0032783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032783", "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "pmid": "" }, { "name": "response to tumor necrosis factor", "id": "GO:0034612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034612", "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "pmid": "" }, { "name": "nervous system process", "id": "GO:0050877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050877", "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "pmid": "" }, { "name": "embryonic hindlimb morphogenesis", "id": "GO:0035116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035116", "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "pmid": "" }, { "name": "DNA-templated transcription elongation", "id": "GO:0006354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006354", "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "E1BJW8", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1026, "end_pos": 1028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1141, "end_pos": 1143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1185, "end_pos": 1187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJW8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1315, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJW8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJW8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJW8" }, { "id": "PF18876", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18876" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AF4/FMR2 C-terminal homology", "eco_id": "ECO_0000259", "start_pos": 1051, "end_pos": 1314, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 647, 1143 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1026, "end_pos": 1028 }, { "start_pos": 1141, "end_pos": 1143 }, { "start_pos": 1185, "end_pos": 1187 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 91, "end_pos": 93 }, { "start_pos": 940, "end_pos": 942 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", 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"count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGG0-1", "uniprot_ac": "E1BGG0", "uniprot_id": "E1BGG0_BOVIN", "mass": { "chemical_mass": 34380.0, "monoisotopic_mass": 34380.0 }, "refseq": { "ac": "NP_001179911", "name": "lysM and putative peptidoglycan-binding domain-containing protein 3", "summary": 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"id": "NP_001179911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179911" } ] } ], "function": [ { "annotation": "Essential for Golgi structural integrity.", "evidence": [ { "database": "UniProtKB", "id": "E1BGG0", "url": "https://www.uniprot.org/uniprotkb/E1BGG0#function" }, { "database": "UniProtKB", "id": "ARBA00037465", "url": "https://www.uniprot.org/uniprotkb/ARBA00037465#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGG0", "url": "https://www.uniprot.org/uniprotkb/E1BGG0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LYSMD3", "url": "https://www.uniprot.org/uniprotkb/E1BGG0", "locus": { "chromosome": "7", "start_pos": 90086049, "end_pos": 90097657, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000027713", "url": "https://www.ensembl.org/id/ENSBTAG00000027713" } ] } } ], "crossref": [ { "id": "E1BGG0", "url": "https://alphafold.ebi.ac.uk/entry/E1BGG0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000027713", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000027713", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "613760", "url": "https://www.ncbi.nlm.nih.gov/gene/613760", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613760", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613760", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IALQFCC", "url": "https://omabrowser.org/oma/group/IALQFCC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGG0", "url": "https://www.orthodb.org/?gene=E1BGG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179911", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179911", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RT05", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RT05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RT05-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RT05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGG0", "url": "https://www.uniprot.org/uniprotkb/E1BGG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGG0-1", "url": "https://www.uniprot.org/uniprotkb/E1BGG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGRHQNRSFPLPGIHSSAQVHAFGNCADSDMLEEDAEVYELRSRGKEKIRRSTSKDRLDDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLYPPKGRQASRPSTVQYLPEQQEVLSANDSLSSTESAGSFLKEVDRDIEQIVKCTDTKRENLNEVVSALTAQQVRFEPDNKNIQRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSGVTPPSQQREMENGIAPTKGIPFGPQDDRKLYNQDSQLPAAQHKT", "length": 306, "header": "tr|E1BGG0-1|E1BGG0_BOVIN Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Bos taurus OX=9913 GN=LYSMD3 PE=4 SV=1 CANONICAL=E1BGG0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RT05-1", "url": "https://www.uniprot.org/uniprotkb/E1BGG0/entry#A0AAA9RT05-1", "sequence": { "sequence": "RTAGLRTWRRRTARKAETLAAAAAATVEEDRGSQRLRLGHELARDRGGGGGPGGRLLVKSPLLTGQVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLYPPKGRQASRPSTVQYLPEQQEVLSANDSLSSTESAGSFLKEVDRDIEQIVKCTDTKRENLNEVVSALTAQQVRFEPDNKNIQRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSGVTPPSQQREMENGIAPTKGIPFGPQDDRKLYNQDSQLPAAQHKT", "length": 287, "header": "tr|A0AAA9RT05-1|E1BGG0_BOVIN Computationally mapped isoform of LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Bos taurus OX=9913 GN=LYSMD3 PE=4 SV=1 CANONICAL=E1BGG0-1" }, "locus": { "chromosome": "7", "start_pos": 90097657, "end_pos": 90087053, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124690.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124690.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074872.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074872.1" } ] } }, { "isoform_ac": "E1BGG0-1", "url": "https://www.uniprot.org/uniprotkb/E1BGG0/entry#E1BGG0-1", "sequence": { "sequence": "MAGRHQNRSFPLPGIHSSAQVHAFGNCADSDMLEEDAEVYELRSRGKEKIRRSTSKDRLDDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLYPPKGRQASRPSTVQYLPEQQEVLSANDSLSSTESAGSFLKEVDRDIEQIVKCTDTKRENLNEVVSALTAQQVRFEPDNKNIQRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSGVTPPSQQREMENGIAPTKGIPFGPQDDRKLYNQDSQLPAAQHKT", "length": 306, "header": "tr|E1BGG0-1|E1BGG0_BOVIN Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Bos taurus OX=9913 GN=LYSMD3 PE=4 SV=1 CANONICAL=E1BGG0-1" }, "locus": { "chromosome": "7", "start_pos": 90092286, "end_pos": 90087053, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039933.5", "url": "https://www.ensembl.org/id/ENSBTAT00000039933.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039717.3", "url": "https://www.ensembl.org/id/ENSBTAP00000039717.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 279, "start_aa": "Thr", "end_pos": 279, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr279", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:613760", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613760", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TE25-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "gene_name": "LYSMD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGRHQNRSYPLPGVHSSGQVHAFGNCTDSDILEEDAEVYELRSRGKEKIRRSTSRDRLDDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLYPPKGRQASRPSSVHYLPEQQELQSANDSLSSSESAGSFLKEVDRDIEQIVKCTDTKRENLNEVVSALTTQQVRFEPDNKNIQRKDPYYGADWGIGWWTAVAIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSGVTPPSQQREMENGIAPTKGIPFGPQDDPKLYSQDAQLPAAQHKT", "length": 306 }, "evidence": [ { "id": "E1BGG0", "url": "https://omabrowser.org/oma/group/E1BGG0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HL69-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "gene_name": "Lysmd3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGRNQNRTISLPGIQASGQVHTFGNCTDNDVLEEDAEVYELRSRGKEKVRRSTSRDRLDDIIILTKDIQEGDTLNAVALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLHPLKGRQGFHPPLVPCAQGQETVAAEDSLCSSESAGSFLKEVDRDIEQIVKCTDTKKENLNEVVSALTAQQIRFEPDSRSTPRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVGSSHLHPGLTPPSQNREMENGIAPTKGIHVGQQDDHRLYRQDSQSPAAQHKT", "length": 305 }, "evidence": [ { "id": "E1BGG0", "url": "https://omabrowser.org/oma/group/E1BGG0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5M836-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "gene_name": "Lysmd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRNQNRTASLAGIQASGHVHTFGNCTDNDMLEEDAEVYELRSRGKEKVRRSTSRDRLDDIVILTKDIQEGDTLNAVALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKRFSSLTETLHPLKGRQVLHPPPVPYFQEQDTVPANDSPSSSESAGSFLKEVDRDIEQIVKCTDTKKENLNEVVSALTAQQVRFEPDNKSVHRKDPYYGADWGMGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHPGLTPPSHHREMGNAIGPTKGIPVGQQDDHRLYRQDPQARD", "length": 300 }, "evidence": [ { "id": "E1BGG0", "url": "https://omabrowser.org/oma/group/E1BGG0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z3D4-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "gene_name": "LYSMD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGRHQNRSFPLPGVQSSGQVHAFGNCSDSDILEEDAEVYELRSRGKEKVRRSTSRDRLDDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLCPPKGRQTSRHSSVQYSSEQQEILPANDSLAYSDSAGSFLKEVDRDIEQIVKCTDNKRENLNEVVSALTAQQMRFEPDNKNTQRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSKITPPSQQREMENGIVPTKGIHFSQQDDHKLYSQDSQSPAAQQET", "length": 306 }, "evidence": [ { "id": "E1BGG0", "url": "https://omabrowser.org/oma/group/E1BGG0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99LE3-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "gene_name": "Lysmd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGRNQNRTVSLPGIQASGHVLAFGNCTDNDMLEEDAEVYELRSRGKEKVRRSASRDRLDDIVILTKDIQEGDTLNAVALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKRFSSLTETLHPLKGRHILHPPPVPYFQEQDIVPADGSLSSSESAGSFLKEVDRDIEQIVKCTDTKKENLNEVVSALTAQQVRFEPDNKSIHRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVGSSHLHPGLTPPTQHREMENEIGPTKGIPVGQQDDHKLYRQDPQAHDAQHKT", "length": 305 }, "evidence": [ { "id": "E1BGG0", "url": "https://omabrowser.org/oma/group/E1BGG0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidoglycan 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Process", "total": 1, "go_terms": [ { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "E1BGG0", "url": "https://www.uniprot.org/uniprotkb/E1BGG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGG0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 306, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGG0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGG0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGG0", 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGK7-1", "uniprot_ac": "E1BGK7", "uniprot_id": "E1BGK7_BOVIN", "mass": { "chemical_mass": 91678.0, "monoisotopic_mass": 91678.0 }, "refseq": {}, "gene_names": [ { "name": "TAF4B", "type": "recommended", "evidence": [ { "id": "E1BGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" } ] } ], "protein_names": [ { "name": "TATA-box binding protein associated factor 4b", "type": "synonym", "evidence": [ { "id": "E1BGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGK7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGK7", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TAF4B", "url": "https://www.uniprot.org/uniprotkb/E1BGK7", "locus": { "chromosome": "24", "start_pos": 30436961, "end_pos": 30607271, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004257", "url": "https://www.ensembl.org/id/ENSBTAG00000004257" } ] } } ], "crossref": [ { "id": "E1BGK7", "url": "https://alphafold.ebi.ac.uk/entry/E1BGK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004257", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004257", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08045", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08045", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BGK7", "url": "https://www.orthodb.org/?gene=E1BGK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15138:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15138:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6804756", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73776", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73776", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73779", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73779", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-75953", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75953", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-76042", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RUH1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RUH1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0K2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0K2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY29", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY29-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T903", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T903", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T903-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T903-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T978", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T978", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T978-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T978-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGK7", "url": "https://www.uniprot.org/uniprotkb/E1BGK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGK7-1", "url": "https://www.uniprot.org/uniprotkb/E1BGK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAGLTEPAGAAPPAGVGASGTVTMAPAAALPVRVESTPVALGAVTKAPVSVCVESSASQPLRSPVGTLVTKVAPVSALPKLSNGPRLPSPQIVAVKAPNTTTIQLPANLQLPPGTVLIKSNSGQLMLVSPQQAVTRTETTSNITSRPAVPANTQTVKICTMPNSSSQLIKKVAVAPVKQLAQVGTTVVTSVPKPSPVQSVAVPTNVVTVTPVKPVNTVTTLKPSSLGTASAPSNELNLKTENSASAQANLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRQLYVELKSSPQPHLVPFLKKSVIALRQLMPNAQSFIQQCVQQTSSEVVTTTCPTTSTPSPVVTTAASSIQAEKPAVVGSEAGVPGVVSVQTLKPLAGPEGAKTGVVTLHSVGPAAVPGGTTAGTVVLQTPKPLVTSLQNTVTAVSLQPEKPVVSGTAVTLALPSVPFGKTSAAAVCIPSVKPILTSSGTTSNKPVLGPPLQIKLAQPGPVLAQPAGIPQAVKVKQLFSLFQVVQQPSGGLAKQVTTLTHSPALTIQKPGQKKVTVSTAIPTSQFSQASILKQVTLPGNKILSLQSSVQKNKIKENGTISFRDEDDINDVTSMAGVNLSEENACILATNSELVGTLIQSCKDEPFLFIGALQKRILDIGKKHDITELNSDAVNLISHATQERLRGLLEKLTTIAQHRMTTYKASENYILSNDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQIQQRDANLTALAAIGPRKKRPLESGSGSEGLKDNLFASGTSSLTASKQLVRPRITRICLRDLIFCMEQERDMKYSRALYLALLK", "length": 869, "header": "tr|E1BGK7-1|E1BGK7_BOVIN Isoform 1 of TATA-box binding protein associated factor 4b OS=Bos taurus OX=9913 GN=TAF4B PE=3 SV=4 CANONICAL=E1BGK7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RUH1-1", "url": "https://www.uniprot.org/uniprotkb/E1BGK7/entry#A0AAA9RUH1-1", "sequence": { "sequence": "MPAGLTEPAGAAPPAGVGASGTVTMAPAAALPVRVESTPVALGAVTKAPVSVCVESSASQPLRSPVGTLVTKVAPVSALPKLSNGPRLPSPQIVAVKAPNTTTIQLPANLQLPPGTVLIKSNSGQLMLVSPQQAVTRTETTSNITSRPAVPANTQTVKICTMPNSSSQLIKKVAVAPVKQLAQVGTTVVTSVPKPSPVQSVAVPTNVVTVTPVKPVNTVTTLKPSSLGTASAPSNELNLKTENSASAQANLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRQLYVELKSSPQPHLVPFLKKSVIALRQLMPNAQSFIQQCVQQTSSEVVTTTCPTTSTPSPVVTTAASSIQAEKPAVVGSEAGVPGVVSVQTLKPLAGPEGAKTGVVTLHSVGPAAVPGGTTAGTVVLQTPKPLVTSLQNTVTAVSLQPEKPVVSGTAVTLALPSVPFGKTSAAAVCIPSVKPILTSSGTTSNKPVLGPPLQIKLAQPGPVLAQPAGIPQAVKVKQLVVQQPSGGLAKQVTTLTHSPALTIQKPGQKKVTVSTAIPTSQFSQASILKQVTLPGNKILSLQSSVQKNKIKENGTISFRDEDDINDVTSMAGVNLSEENACILATNSELVGTLIQSCKDEPFLFIGALQKRILDIGKKHDITELNSDAVNLISHATQERLRGLLEKLTTIAQHRMTTYKASENYILSNDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQIQQRDANLTALAAIGPRKKRPLESGSGSELPWNGISGSQQEQSG", "length": 824, "header": "tr|A0AAA9RUH1-1|E1BGK7_BOVIN Computationally mapped isoform of TATA-box binding protein associated factor 4b OS=Bos taurus OX=9913 GN=TAF4B PE=3 SV=1 CANONICAL=E1BGK7-1" }, "locus": { "chromosome": "24", "start_pos": 30607258, "end_pos": 30485380, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094552.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094552.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075797.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075797.1" } ] } }, { "isoform_ac": "A0AAA9S0K2-1", "url": "https://www.uniprot.org/uniprotkb/E1BGK7/entry#A0AAA9S0K2-1", "sequence": { "sequence": "MPAGLTEPAGAAPPAGVGASGTVTMAPAAALPVRVESTPVALGAVTKAPVSVCVESSASQPLRSPVGTLVTKVAPVSALPKLSNGPRLPSPQIVAVKAPNTTTIQLPANLQLPPGTVLIKSNSGQLMLVSPQQAVTRTETTSNITSRPAVPANTQTVKICTMPNSSSQLIKKVAVAPVKQLAQVGTTVVTSVPKPSPVQSVAVPTNVVTVTPVKPVNTVTTLKPSSLGTASAPSNELNLKTENSASAQANLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRQLYVELKSSPQPHLVPFLKKSVIALRQLMPNAQSFIQQCVQQTSSEVVTTTCPTTSTPSPVVTTAASSIQAEKPAVVGSEAGVPGVVSVQTLKPLAGPEGAKTGVVTLHSVGPAAVPGGTTAGTVVLQTPKPLVTSLQNTVTAVSLQPEKPVVSGTAVTLALPSVPFGKTSAAAVCIPSVKPILTSSGTTSNKPVLGPPLQIKLAQPGPVLAQPAGIPQAVKVKQLVVQQPSGGLAKQVTTLTHSPALTIQKPGQKKVTVSTAIPTSQFSQASILKQVTLPGNKILSLQSSVQKNKIKENGTISFRDEDDINDVTSMAGVNLSEENACILATNSELVGTLIQSCKDEPFLFIGALQKRILDIGKKHDITELNSDAVNLISHATQERLRGLLEKLTTIAQHRMTTYKASENYILSNDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQIQQRDANLTALAAIGPRKKRPLESGSGSEISGGKHIHIAAPHTRRTFSSCKTETLYPLNNSPSSPFP", "length": 847, "header": "tr|A0AAA9S0K2-1|E1BGK7_BOVIN Computationally mapped isoform of TATA-box binding protein associated factor 4b OS=Bos taurus OX=9913 GN=TAF4B PE=3 SV=1 CANONICAL=E1BGK7-1" }, "locus": { "chromosome": "24", "start_pos": 30607258, "end_pos": 30522285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106896.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106896.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077163.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077163.1" } ] } }, { "isoform_ac": "A0AAA9SY29-1", "url": "https://www.uniprot.org/uniprotkb/E1BGK7/entry#A0AAA9SY29-1", "sequence": { "sequence": "MPAGLTEPAGAAPPAGVGASGTVTMAPAAALPVRVESTPVALGAVTKAPVSVCVESSASQPLRSPVGTLVTKVAPVSALPKLSNGPRLPSPQIVAVKAPNTTTIQLPANLQLPPGTVLIKSNSGQLMLVSPQQAVTRTETTSNITSRPAVPANTQTVKICTMPNSSSQLIKKVAVAPVKQLAQVGTTVVTSVPKPSPVQSVAVPTNVVTVTPVKPVNTVTTLKPSSLGTASAPSNELNLKTENSASAQANLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRQLYVELKSSPQPHLVPFLKKSVIALRQLMPNAQSFIQQCVQQTSSEVVTTTCPTTSTPSPVVTTAASSIQAEKPAVVGSEAGVPGVVSVQTLKPLAGPEGAKTGVVTLHSVGPAAVPGGTTAGTVVLQTPKPLVTSLQNTVTAVSLQPEKPVVSGTAVTLALPSVPFGKTSAAAVCIPSVKPILTSSGTTSNKPVLGPPLQIKLAQPGPVLAQPAGIPQAVKVKQLVVQQPSGGLAKQVTTLTHSPALTIQKPGQKKVTVSTAIPTSQFSQASILKQVTLPGNKILSLQSSVQKNKIKENGTISFRDEDDINDVTSMAGVNLSEENACILATNSELVGTLIQSCKDEPFLFIGALQKRILDIGKKHDITELNSDAVNLISHATQERLRGLLEKLTTIAQHRMTTYKASENYILSNDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKEPQRKKLH", "length": 779, "header": "tr|A0AAA9SY29-1|E1BGK7_BOVIN Computationally mapped isoform of TATA-box binding protein associated factor 4b OS=Bos taurus OX=9913 GN=TAF4B PE=3 SV=1 CANONICAL=E1BGK7-1" }, "locus": { "chromosome": "24", "start_pos": 30607258, "end_pos": 30536725, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108933.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108933.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090268.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090268.1" } ] } }, { "isoform_ac": "A0AAA9T903-1", "url": "https://www.uniprot.org/uniprotkb/E1BGK7/entry#A0AAA9T903-1", "sequence": { "sequence": "MPAGLTEPAGAAPPAGVGASGTVTMAPAAALPVRVESTPVALGAVTKAPVSVCVESSASQPLRSPVGTLVTKVAPVSALPKLSNGPRLPSPQIVAVKAPNTTTIQLPANLQLPPGTVLIKSNSGQLMLVSPQQAVTRTETTSNITSRPAVPANTQTVKICTMPNSSSQLIKKVAVAPVKQLAQVGTTVVTSVPKPSPVQTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRQLYVELKSSPQPHLVPFLKKSVIALRQLMPNAQSFIQQCVQQTSSEVVTTTCPTTSTPSPVVTTAASSIQAEKPAVVGSEAGVPGVVSVQTLKPLAGPEGAKTGVVTLHSVGPAAVPGGTTAGTVVLQTPKPLVTSLQNTVTAVSLQPEKPVVSGTAVTLALPSVPFGKTSAAAVCIPSVKPILTSSGTTSNKPVLGPPLQIKLAQPGPVLAQPAGIPQAVKVKQLVVQQPSGGLAKQVTTLTHSPALTIQKPGQKKVTVSTAIPTSQFSQASILKQVTLPGNKILSLQSSVQKNKIKENGTISFRDEDDINDVTSMAGVNLSEENACILATNSELVGTLIQSCKDEPFLFIGALQKRILDIGKKHDITELNSDAVNLISHATQERLRGLLEKLTTIAQHRMTTYKASENYILSNDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQIQQRDANLTALAAIGPRKKRPLESGSGSEGLKDNLFASGTSSLTASKQLVRPRITRICLRDLIFCMEQERDMKYSRALYLALLK", "length": 810, "header": "tr|A0AAA9T903-1|E1BGK7_BOVIN Computationally mapped isoform of TATA-box binding protein associated factor 4b OS=Bos taurus OX=9913 GN=TAF4B PE=3 SV=1 CANONICAL=E1BGK7-1" }, "locus": { "chromosome": "24", "start_pos": 30607258, "end_pos": 30501760, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105993.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105993.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092372.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092372.1" } ] } }, { "isoform_ac": "A0AAA9T978-1", "url": "https://www.uniprot.org/uniprotkb/E1BGK7/entry#A0AAA9T978-1", "sequence": { "sequence": "MPAGLTEPAGAAPPAGVGASGTVTMAPAAALPVRVESTPVALGAVTKAPVSVCVESSASQPLRSPVGTLVTKVAPVSALPKLSNGPRLPSPQIVAVKAPNTTTIQLPANLQLPPGTVLIKSNSGQLMLVSPQQAVTRTETTSNITSRPAVPANTQTVKICTMPNSSSQLIKKVAVAPVKQLAQVGTTVVTSVPKPSPVQSVAVPTNVVTVTPVKPVNTVTTLKPSSLGTASAPSNELNLKTENSASAQANLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRQLYVELKSSPQPHLVPFLKKSVIALRQLMPNAQSFIQQCVQQTSSEVVTTTCPTTSTPSPVVTTAASSIQAEKPAVVGSEAGVPGVVSVQTLKPLAGPEGAKTGVVTLHSVGPAAVPGGTTAGTVVLQTPKPLVTSLQNTVTAVSLQPEKPVVSGTAVTLALPSVPFGKTSAAAVCIPSVKPILTSSGTTSNKPVLGPPLQIKLAQPGPVLAQPAGIPQAVKVKQLVVQQPSGGLAKQVTTLTHSPALTIQKPGQKKVTVSTAIPTSQFSQASILKQVTLPGNKILSLQSSVQKNKIKENGTISFRDEDDINDVTSMAGVNLSEENACILATNSELVGTLIQSCKDEPFLFIGALQKRILDIGKKHDITELNSDAVNLISHATQERLRGLLEKLTTIAQHRMTTYKASENYILSNDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQIQQRDANLTALAAIGPRKKRPLESGSGSEKKYIHLVQRLLLYPDDRGSTGCPPQFPPQDVFAELR", "length": 845, "header": "tr|A0AAA9T978-1|E1BGK7_BOVIN Computationally mapped isoform of TATA-box binding protein associated factor 4b OS=Bos taurus OX=9913 GN=TAF4B PE=3 SV=1 CANONICAL=E1BGK7-1" }, "locus": { "chromosome": "24", "start_pos": 30607258, "end_pos": 30437965, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125350.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125350.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092453.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092453.1" } ] } }, { "isoform_ac": "E1BGK7-1", "url": "https://www.uniprot.org/uniprotkb/E1BGK7/entry#E1BGK7-1", "sequence": { "sequence": "MPAGLTEPAGAAPPAGVGASGTVTMAPAAALPVRVESTPVALGAVTKAPVSVCVESSASQPLRSPVGTLVTKVAPVSALPKLSNGPRLPSPQIVAVKAPNTTTIQLPANLQLPPGTVLIKSNSGQLMLVSPQQAVTRTETTSNITSRPAVPANTQTVKICTMPNSSSQLIKKVAVAPVKQLAQVGTTVVTSVPKPSPVQSVAVPTNVVTVTPVKPVNTVTTLKPSSLGTASAPSNELNLKTENSASAQANLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRQLYVELKSSPQPHLVPFLKKSVIALRQLMPNAQSFIQQCVQQTSSEVVTTTCPTTSTPSPVVTTAASSIQAEKPAVVGSEAGVPGVVSVQTLKPLAGPEGAKTGVVTLHSVGPAAVPGGTTAGTVVLQTPKPLVTSLQNTVTAVSLQPEKPVVSGTAVTLALPSVPFGKTSAAAVCIPSVKPILTSSGTTSNKPVLGPPLQIKLAQPGPVLAQPAGIPQAVKVKQLFSLFQVVQQPSGGLAKQVTTLTHSPALTIQKPGQKKVTVSTAIPTSQFSQASILKQVTLPGNKILSLQSSVQKNKIKENGTISFRDEDDINDVTSMAGVNLSEENACILATNSELVGTLIQSCKDEPFLFIGALQKRILDIGKKHDITELNSDAVNLISHATQERLRGLLEKLTTIAQHRMTTYKASENYILSNDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQIQQRDANLTALAAIGPRKKRPLESGSGSEGLKDNLFASGTSSLTASKQLVRPRITRICLRDLIFCMEQERDMKYSRALYLALLK", "length": 869, "header": "tr|E1BGK7-1|E1BGK7_BOVIN Isoform 1 of TATA-box binding protein associated factor 4b OS=Bos taurus OX=9913 GN=TAF4B PE=3 SV=4 CANONICAL=E1BGK7-1" }, "locus": { "chromosome": "24", "start_pos": 30607258, "end_pos": 30501760, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005578.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005578.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005578.6", "url": "https://www.ensembl.org/id/ENSBTAP00000005578.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 362, "start_aa": "Thr", "end_pos": 362, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr362", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-BTA-6804756", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "resource": "Reactome", "description": "Regulation of TP53 Activity through Phosphorylation" }, { "id": "R-BTA-73776", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73776", "resource": "Reactome", "description": "RNA Polymerase II Promoter Escape" }, { "id": "R-BTA-73779", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73779", "resource": "Reactome", "description": "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" }, { "id": "R-BTA-75953", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75953", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation" }, { "id": "R-BTA-76042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76042", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation And Promoter Clearance" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BGK7", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "E1BGK7", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" } ], "pmid": "" }, { "name": "DNA-templated transcription initiation", "id": "GO:0006352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006352", "evidence": [ { "database": "UniProtKB", "id": "E1BGK7", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" } ], "pmid": "" }, { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "E1BGK7", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "E1BGK7", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" } ], "pmid": "" }, { "name": "mRNA transcription by RNA polymerase II", "id": "GO:0042789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042789", "evidence": [ { "database": "UniProtKB", "id": "E1BGK7", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "E1BGK7", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BGK7", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" } ], "pmid": "" }, { "name": "NF-kappaB binding", "id": "GO:0051059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051059", "evidence": [ { "database": "UniProtKB", "id": "E1BGK7", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "E1BGK7", "url": 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"interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGK7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 869, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGK7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGK7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGK7" }, { "id": "PS51119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TAFH", "eco_id": "ECO_0000259", "start_pos": 256, "end_pos": 353, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIA4-1", "uniprot_ac": "E1BIA4", "uniprot_id": "E1BIA4_BOVIN", "mass": { "chemical_mass": 194682.0, "monoisotopic_mass": 194682.0 }, "refseq": { "ac": "XP_005222609", "name": "deleted in lung and esophageal cancer protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222609" }, "gene_names": [ { "name": "DLEC1", "type": "recommended", "evidence": [ { "id": "E1BIA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" } ] }, { "name": "DLEC1", "type": "synonym", "evidence": [ { "id": "XP_005222609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222609" } ] } ], "protein_names": [ { "name": "DLEC1 cilia and flagella associated protein", "type": "synonym", "evidence": [ { "id": "E1BIA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA4/entry#names_and_taxonomy" } ] }, { 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"https://bgee.org/?page=gene&gene_id=ENSBTAG00000008567", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618746", "url": "https://www.ncbi.nlm.nih.gov/gene/618746", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060480", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060480", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BIA4", "url": "https://www.orthodb.org/?gene=E1BIA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46348:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46348:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23316", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23316", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005222609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222609", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RY63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RY63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RY63-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RY63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCC9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCC9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIA4", "url": "https://www.uniprot.org/uniprotkb/E1BIA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIA4-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METGKRERQSAESGSYAFAGATWTPSPRLARIRSPSQSTWLSSLAYSESFHHGFGGRRRFVAQLSLPPLPEPQLLRLRPTSLRTQDISYLLTGVFRNLYTAEVIGEEVSSNLIKARGSEDARHEEFVDQLQQIRELYKQRLDEVEMLERHIIQARARALAEKERAMHQAKVQFLEPFIKMPPVKTIFRWCVDNELLRKHHLICPNDYYSDTVPFCSAPKGVSVPGYSKPTFSSEKRSIPKKELTKKPACRKMSSQSAEETDYTMDSLTWDSSFKAKLRSRAAIRKTGLPKNKNWMNHLRVPQRQLERLQLARMESRNRFLRNPRFFPPNTPLGGKSLLFPPKKPARVGAFQDGELEESCADTPVFLAKPSIGFFTDYEIGPVYEMVISLQNTTSTSRHLRVLPPSTPYFALGLGMFPGEGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCGYCLIGGMKITRFICKNVGFSVGKFCIMPKKSWPPPSFRAVVTIGFVEQPPFGILPSVFELVPGQAVFVEVLFLPTSLGKAEQTFVIVCDNCQIKELVTTGVGQLVALDLIYISGEKSQPEPGELTDLTAQYFIRFEPENLQSTASKLLIIRNATHVELAFHWQIMKPNLQSLMPGETYSTDSIKYHPDRETAFCITPKMGVLSPHTDHEFILSFSPQEPRDFHSVLQMVLEEVPEPVSLDLENSKDPSYCMDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKNFKMWNNSKSTIRYTWGKISDCHIIEVEPCTGTIEPSEVEDFELNFTGGVPGPTSQNLLCEIKDSPTPVVLHIEAAFKGPALVIDVSALQFGLLRLGQKATKFIQIRNLSQLPATWAMKESQVSLQERQEGVSPFDIEPSSGQVQPLGECRVSITLEAQHCQRLQTVLELEVVDGTWSHLPVYAEVQEPYVYLQSSQVEVPNLYLGVPTKMAITLINGTLLPTRFHWGKLLGLQADVCTVKVSPRRGTLGPSEERQLSLELTAHTLEAVTDLALPCDVSGMREPLVLGISGKPRGLQVAIGISKEDSDDSAPSTELWPGHPETLHLDFGSAVPLWTRVNRRLFLTNCSPIQTPFTLEFEYFGSPVNSLSQKPSPPDMPPALLKTARMRELLAKREQWEFMESMLSHGKGAAFFPHLSQGVLGAHQKLSIDLTACANMWGEYWDSLICTVGGLPPAVIPVRMAVVGCPISSQRTTYYTTDQTQREPIIRFGTRVSGGDPVTRILRLNNSSPCDIRLDWETYTPEDREDRLLELLVFYGPPFPLRDHAGNDLLYPETPESSGSFWSPSPSESESSREATPSAEGSSSAGAPQKIISVILRGHEGVPSDHLFSISPKQVVVPARGSSTIHISFTPVVLGPGVLHKVECVGYALGFLSLDDEVERELPGRRRRLQDFAMGPMRLDLHGYVRPAQLSVDWDYGGSMVFRQQASDLIPEQPCAGVLSELVTTRHLKLTNTTEIPHYFWLLVSKPFSISQDGASRSHRALGWKQEGEEIAARGKQLVLHPQENMLVNVSFSLSLELLSYQKLPADQMLPGVDIQQSPSGEKQMVFTQNLLLEYSNQTSQVVPLRAVVAVPELQLSTSWVDFGPCFVNQGRAREVYLMNLSGCRSYWAVLTGQQEPDRDPVAFKVSPSSGLLEARPVNAPPTSVTLQVSFTARSCELYESTLVVEGVLGEKPCTLRLRGRGSYDERHASPQHQL", "length": 1746, "header": "tr|E1BIA4-1|E1BIA4_BOVIN Isoform 1 of DLEC1 cilia and flagella associated protein OS=Bos taurus OX=9913 GN=DLEC1 PE=4 SV=4 CANONICAL=E1BIA4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RY63-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA4/entry#A0AAA9RY63-1", "sequence": { "sequence": "METGKRERQSAESGSYAFAGATWTPSPRLARIRSPSQSTWLSSLAYSESFHHGFGGRRRFVAQLSLPPLPEPQLLRLRPTSLRTQDISYLLTGVFRNLYTAEVIGEEVSSNLIKARGSEDARHEEFVDQLQQIRELYKQRLDEVEMLERHIIQARARALAEKERAMHQAKVQFLEPFIKMPPVKTIFRWCVDNELLRKHHLICPNDYYSDTVPFCSAPKGVSVPGYSKPTFSSEKRSIPKKELTKKPACRKMSSQSAEETDYTMDSLTWDSSFKAKLRSRAAIRKTGLPKNKNWMNHLRVPQRQLERLQLARMESRNRFLRNPRFFPPNTPLGGKSLLFPPKKPARVGAFQDGELEESCADTPVFLAKPSIGFFTDYEIGPVYEMVISLQNTTSTSRHLRVLPPSTPYFALGLGMFPGEGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCGYCLIGGMKITRFICKNVGFSVGKFCIMPKKSWPPPSFRAVVTIGFVEQPPFGILPSVFELVPGQAVFVEVLFLPTSLGKAEQTFVIVCDNCQIKELVTTGVGQLVALDLIYISGEKSQPEPGELTDLTAQYFIRFEPENLQSTASKLLIIRNATHVELAFHWQIMKPNLQSLMPGETYSTDSIKYHPDRETAFCITPKMGVLSPHTDHEFILSFSPQEPRDFHSVLQMVLEEVPEPVSLDLENSKDPSYCMDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKNFKMWNNSKSTIRYTWGKISDCHIIEVEPCTGTIEPSEVEDFELNFTGGVPGPTSQNLLCEIKDSPTPVVLHIEAAFKGPALVIDVSALQFGLLRLGQKATKFIQIRNLSQLPATWAMKESQVSLQERQEGVSPFDIEPSSGQVQPLGECRVSITLEAQHCQRLQTVLELEVVDGTWSHLPVYAEVQEPYVYLQSSQVEVPNLYLGVPTKMAITLINGTLLPTRFHWGKLLGLQADVCTVKVSPRRGTLGPSEERQLSLELTAHTLEAVTDLALPCDVSGMREPLVLGISGKPRGLQVAIGISKEDSDDSAPSTELWPGHPETLHLDFGSAVPLWTRVNRRLFLTNCSPIQTPFTLEFEYFGSPVNSLSQKPSPPDMPPALLKTARMRELLAKREQWEFMESMLSHGKGAAFFPHLSQGVLGAHQKLSIDLTACANMWGEYWDSLICTVGGLPPAVIPVRMAVVGCPISSQRTTYYTTDQTQREPIIRFGTRVSGGDPVTRILRLNNSSPCDIRLDWETYTPEDREDRLLELLVFYGPPFPLRDHAGNDLLYPETPESSGSFWSPSPSESESSREATPSAEGSSSAGAPQKIISVILRGHEGVPSDHLFSISPKQVVVPARGSSTIHISFTPVVLGPGVLHKVECVGYALGFLSLDDEVERELPGRRRRLQDFAMGPMRLDLHGYVRPAQLSVDWDYGGSMVFRQQASDLIPEQPCAGVLSELVTTRHLKLTNTTEIPHYFWLLVSKPFSISQDGASRSHRALGWKQEGEEIAARGKQLVLHPQENMLVNVSFSLSLELLSYQKLPADQMLPGVDIQQSPSGEKQMVFTQNLLLEYSNQTSQVSPQPGSRVKEGHRAELCSGGVNGGLTPIVWHVERWGHLHPYRPRELRARWGAGGCKIREGFLEEEAAREACTLFNGESGGPGQGSGLTMLTAAEGRLWGLSGTVCTR", "length": 1720, "header": "tr|A0AAA9RY63-1|E1BIA4_BOVIN Computationally mapped isoform of DLEC1 cilia and flagella associated protein OS=Bos taurus OX=9913 GN=DLEC1 PE=4 SV=1 CANONICAL=E1BIA4-1" }, "locus": { "chromosome": "22", "start_pos": 11581151, "end_pos": 11491792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132241.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132241.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077540.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077540.1" } ] } }, { "isoform_ac": "A0AAA9SCC9-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA4/entry#A0AAA9SCC9-1", "sequence": { "sequence": "METGKRERQSAESGSYAFAGATWTPSPRLARIRSPSQSTWLSSLAYSESFHHGFGGRRRFVAQLSLPPLPEPQLLRLRPTSLRTQDISYLLTGVFRNLYTAEVIGEEVSSNLIKARGSEDARHEEFVDQLQQIRELYKQRLDEVEMLERHIIQARARALAEKERAMHQAKVQFLEPFIKMPPVKTIFRWCVDNELLRKHHLICPNDYYSDTVPFCSAPKGVSVPGYSKPTFSSEKRSIPKKELTKKPACRKMSSQSAEETDYTMDSLTWDSSFKAKLRSRAAIRKTGLPKNKNWMNHLRVPQRQLERLQLARMESRNRFLRNPRFFPPNTPLGGKSLLFPPKKPARVGAFQDGELEESCADTPVFLAKPSIGFFTDYEIGPVYEMVISLQNTTSTSRHLRVLPPSTPYFALGLGMFPGEGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCGYCLIGGMKITRFICKNVGFSVGKFCIMPKKSWPPPSFRAVVTIGFVEQPPFGILPSVFELVPGQAVFVEVLFLPTSLGKAEQTFVIVCDNCQIKELVTTGVGQLVALDLIYISGEKSQPEPGELTDLTAQYFIRFEPENLQSTASKLLIIRNATHVELAFHWQIMKPNLQSLMPGETYSTDSIKYHPDRETAFCITPKMGVLSPHTDHEFILSFSPQEPRDFHSVLQMVLEEVPEPVSLDLENSKDPSYCMDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKNFKMWNNSKSTIRYTWGKISDCHIIEVEPCTGTIEPSEVEDFELNFTGGVPGPTSQNLLCEIKDSPTPVVLHIEAAFKGPALVIDVSALQFGLLRLGQKATKFIQIRNLSQLPATWAMKESQVSLQERQEGVSPFDIEPSSGQVQPLGECRVSITLEAQHCQRLQTVLELEVVDGTWSHLPVYAEVQEPYVYLQSSQVEVPNLYLGVPTKMAITLINGTLLPTRFHWGKLLGLQADVCTVKVSPRRGTLGPSEERQLSLELTAHTLEAVTDLALPCDVSGMREPLVLGISGKPRGLQVAIGISKEDSDDSAPSTELWPGHPETLHLDFGSAVPLWTRVNRRLFLTNCSPIQTPFTLEFEYFGSPVNSLSQKPSPPDMPPALLKTARMRELLAKREQWEFMESMLSHGKGAAFFPHLSQGVLGAHQKLSIDLTACANMWGEYWDSLICTVGGLPPAVIPVRMAVVGCPISSQRTTYYTTDQTQREPIIRFGTRVSGGDPVTRILRLNNSSPCDIRLDWETYTPEDREDRLLELLVFYGPPFPLRDHAGNDLLYPETPESSGSFWSPSPSESESSREATPSAEGSSSAGAPQKIISVILRGHEGVPSDHLFSISPKQVVVPARGSSTIHISFTPVVLGPGVLHKVECVGYALGFLSLDDEVERELPGRRRRLQDFAMGPMRLDLHGYVRPAQLSVDWDYGGSMVFRQQASDLIPEQPCAGVLSELVTTRHLKLTNTTEIPHYFWLLVSKPFSISQDGASRSHRALGWKQEGEEIAARGKQLVLHPQENMLVNVSFSLSLELLSYQKLPADQMLPGVDIQQSPSGEKQMVFTQNLLLEYSNQTSQVVPLRAVVAVPELQLSTSWVDFGPCFVNQGRAREVYLMNLSGCRSYWAVLTGVLDPPPQLR", "length": 1673, "header": "tr|A0AAA9SCC9-1|E1BIA4_BOVIN Computationally mapped isoform of DLEC1 cilia and flagella associated protein OS=Bos taurus OX=9913 GN=DLEC1 PE=4 SV=1 CANONICAL=E1BIA4-1" }, "locus": { "chromosome": "22", "start_pos": 11581687, "end_pos": 11491792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125372.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125372.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083779.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083779.1" } ] } }, { "isoform_ac": "E1BIA4-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA4/entry#E1BIA4-1", "sequence": { "sequence": "METGKRERQSAESGSYAFAGATWTPSPRLARIRSPSQSTWLSSLAYSESFHHGFGGRRRFVAQLSLPPLPEPQLLRLRPTSLRTQDISYLLTGVFRNLYTAEVIGEEVSSNLIKARGSEDARHEEFVDQLQQIRELYKQRLDEVEMLERHIIQARARALAEKERAMHQAKVQFLEPFIKMPPVKTIFRWCVDNELLRKHHLICPNDYYSDTVPFCSAPKGVSVPGYSKPTFSSEKRSIPKKELTKKPACRKMSSQSAEETDYTMDSLTWDSSFKAKLRSRAAIRKTGLPKNKNWMNHLRVPQRQLERLQLARMESRNRFLRNPRFFPPNTPLGGKSLLFPPKKPARVGAFQDGELEESCADTPVFLAKPSIGFFTDYEIGPVYEMVISLQNTTSTSRHLRVLPPSTPYFALGLGMFPGEGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCGYCLIGGMKITRFICKNVGFSVGKFCIMPKKSWPPPSFRAVVTIGFVEQPPFGILPSVFELVPGQAVFVEVLFLPTSLGKAEQTFVIVCDNCQIKELVTTGVGQLVALDLIYISGEKSQPEPGELTDLTAQYFIRFEPENLQSTASKLLIIRNATHVELAFHWQIMKPNLQSLMPGETYSTDSIKYHPDRETAFCITPKMGVLSPHTDHEFILSFSPQEPRDFHSVLQMVLEEVPEPVSLDLENSKDPSYCMDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKNFKMWNNSKSTIRYTWGKISDCHIIEVEPCTGTIEPSEVEDFELNFTGGVPGPTSQNLLCEIKDSPTPVVLHIEAAFKGPALVIDVSALQFGLLRLGQKATKFIQIRNLSQLPATWAMKESQVSLQERQEGVSPFDIEPSSGQVQPLGECRVSITLEAQHCQRLQTVLELEVVDGTWSHLPVYAEVQEPYVYLQSSQVEVPNLYLGVPTKMAITLINGTLLPTRFHWGKLLGLQADVCTVKVSPRRGTLGPSEERQLSLELTAHTLEAVTDLALPCDVSGMREPLVLGISGKPRGLQVAIGISKEDSDDSAPSTELWPGHPETLHLDFGSAVPLWTRVNRRLFLTNCSPIQTPFTLEFEYFGSPVNSLSQKPSPPDMPPALLKTARMRELLAKREQWEFMESMLSHGKGAAFFPHLSQGVLGAHQKLSIDLTACANMWGEYWDSLICTVGGLPPAVIPVRMAVVGCPISSQRTTYYTTDQTQREPIIRFGTRVSGGDPVTRILRLNNSSPCDIRLDWETYTPEDREDRLLELLVFYGPPFPLRDHAGNDLLYPETPESSGSFWSPSPSESESSREATPSAEGSSSAGAPQKIISVILRGHEGVPSDHLFSISPKQVVVPARGSSTIHISFTPVVLGPGVLHKVECVGYALGFLSLDDEVERELPGRRRRLQDFAMGPMRLDLHGYVRPAQLSVDWDYGGSMVFRQQASDLIPEQPCAGVLSELVTTRHLKLTNTTEIPHYFWLLVSKPFSISQDGASRSHRALGWKQEGEEIAARGKQLVLHPQENMLVNVSFSLSLELLSYQKLPADQMLPGVDIQQSPSGEKQMVFTQNLLLEYSNQTSQVVPLRAVVAVPELQLSTSWVDFGPCFVNQGRAREVYLMNLSGCRSYWAVLTGQQEPDRDPVAFKVSPSSGLLEARPVNAPPTSVTLQVSFTARSCELYESTLVVEGVLGEKPCTLRLRGRGSYDERHASPQHQL", "length": 1746, "header": "tr|E1BIA4-1|E1BIA4_BOVIN Isoform 1 of DLEC1 cilia and flagella associated protein OS=Bos taurus OX=9913 GN=DLEC1 PE=4 SV=4 CANONICAL=E1BIA4-1" }, "locus": { "chromosome": "22", "start_pos": 11582219, "end_pos": 11491792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011298.8", "url": "https://www.ensembl.org/id/ENSBTAT00000011298.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011298.7", "url": "https://www.ensembl.org/id/ENSBTAP00000011298.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1347, "start_aa": "Thr", "end_pos": 1347, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1347", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 824, "start_aa": "Thr", "end_pos": 824, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr824", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "E1BIA4", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" } ], "pmid": "" }, { "name": "defense response to tumor cell", "id": "GO:0002357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002357", "evidence": [ { "database": "UniProtKB", "id": "E1BIA4", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BIA4", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BIA4", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "E1BIA4", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "E1BIA4", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "E1BIA4", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "E1BIA4", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1116, "end_pos": 1118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1276, "end_pos": 1278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1277, "end_pos": 1279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1503, "end_pos": 1505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1560, "end_pos": 1562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1608, "end_pos": 1610, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1651, "end_pos": 1653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" }, { "start_pos": 815, "end_pos": 817, "annotation": "n_glycosylation_sequon" }, { "start_pos": 878, "end_pos": 880, "annotation": "n_glycosylation_sequon" }, { "start_pos": 987, "end_pos": 989, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" }, { "id": "PF28484", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28484" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DLEC1 helical", "eco_id": "ECO_0000259", "start_pos": 135, "end_pos": 211, "start_aa": "Glu", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BIA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" }, { "id": "PF23316", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DLEC1 sixth Ig-like", "eco_id": "ECO_0000259", "start_pos": 959, "end_pos": 1062, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BIA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA4" }, { "id": "PF23277", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23277" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Deleted in lung and esophageal cancer protein 1 Ig-like", "eco_id": "ECO_0000259", "start_pos": 365, "end_pos": 451, "start_aa": "Phe", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 824, 1347 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1116, "end_pos": 1118 }, { "start_pos": 1276, "end_pos": 1278 }, { "start_pos": 1277, "end_pos": 1279 }, { "start_pos": 1503, "end_pos": 1505 }, { "start_pos": 1560, "end_pos": 1562 }, { "start_pos": 1608, "end_pos": 1610 }, { "start_pos": 1651, "end_pos": 1653 }, { "start_pos": 391, "end_pos": 393 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 776, "end_pos": 778 }, { "start_pos": 815, "end_pos": 817 }, { "start_pos": 878, "end_pos": 880 }, { "start_pos": 987, "end_pos": 989 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BE33-1", "uniprot_ac": "E1BE33", "uniprot_id": "E1BE33_BOVIN", "mass": { "chemical_mass": 139546.0, "monoisotopic_mass": 139546.0 }, "refseq": {}, "gene_names": [ { "name": "ZEB2", "type": "recommended", "evidence": [ { "id": "E1BE33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE33" } ] } ], "protein_names": [ { "name": "Zinc finger E-box-binding homeobox 2", "type": "recommended", "evidence": [ { "id": "E1BE33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE33/entry#names_and_taxonomy" } ] }, { "name": "Smad-interacting protein 1", "type": "synonym", "evidence": [ { "id": "E1BE33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE33/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger homeobox protein 1b", "type": "synonym", "evidence": [ { "id": "E1BE33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE33/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin. Represses expression of MEOX2.", "evidence": [ { "database": "UniProtKB", "id": "E1BE33", "url": "https://www.uniprot.org/uniprotkb/E1BE33#function" }, { "database": "UniProtKB", "id": "ARBA00058733", "url": "https://www.uniprot.org/uniprotkb/ARBA00058733#function" }, { "database": "UniProtKB", "id": "A0AAA9S0L5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0L5#function" }, { "database": "UniProtKB", "id": "A0AAA9S258", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S258#function" }, { "database": "UniProtKB", "id": "A0AAA9SAU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAU2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BE33", "url": "https://www.uniprot.org/uniprotkb/E1BE33" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZEB2", "url": "https://www.uniprot.org/uniprotkb/E1BE33", "locus": { "chromosome": "2", "start_pos": 52306542, "end_pos": 52173847, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012615", "url": "https://www.ensembl.org/id/ENSBTAG00000012615" } ] } } ], "crossref": [ { "id": "E1BE33", "url": "https://alphafold.ebi.ac.uk/entry/E1BE33", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012615", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012615", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539873", "url": "https://www.ncbi.nlm.nih.gov/gene/539873", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24391", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24391", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24391:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24391:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9762293", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9762293", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RZL0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0L5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0L5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0L5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S258", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S258", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S258-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S258-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVD9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE33", "url": "https://www.uniprot.org/uniprotkb/E1BE33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE33-1", "url": "https://www.uniprot.org/uniprotkb/E1BE33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHFEDIEPACCRSRAPSPCELPSDPLLSMKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKPQIAEEDGIANPLDQERSPASVPNHESSPHVSQALLPREEEEDEIREGGVEHAWHNSDILQASVDGPEEMKEDYDTMGPEATIQTTVNNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGALGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERNSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKSKTKVGSINLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDSKSANPVFGMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKPGFQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM", "length": 1243, "header": "tr|E1BE33-1|E1BE33_BOVIN Isoform 1 of Zinc finger E-box-binding homeobox 2 OS=Bos taurus OX=9913 GN=ZEB2 PE=3 SV=4 CANONICAL=E1BE33-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RZL0-1", "url": "https://www.uniprot.org/uniprotkb/E1BE33/entry#A0AAA9RZL0-1", "sequence": { "sequence": "MTHFEDIEPACCRSRAPSPCELPSDPLLSMKQPIMADGPRCKRRKQANPRRKNAFEAEMSAWSRRCLAAACHWPGPVVTCKVCCFPR", "length": 87, "header": "tr|A0AAA9RZL0-1|E1BE33_BOVIN Computationally mapped isoform of Zinc finger E-box-binding homeobox 2 OS=Bos taurus OX=9913 GN=ZEB2 PE=3 SV=1 CANONICAL=E1BE33-1" }, "locus": { "chromosome": "2", "start_pos": 52180603, "end_pos": 52176654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120095.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120095.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075240.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075240.1" } ] } }, { "isoform_ac": "A0AAA9S0L5-1", "url": "https://www.uniprot.org/uniprotkb/E1BE33/entry#A0AAA9S0L5-1", "sequence": { "sequence": "MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKPQIAEEDGIANPLDQERSPASVPNHESSPHVSQALLPREEEEDEIREGGVEHAWHNSDILQASVDGPEEMKEDYDTMGPEATIQTTVNNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGALGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERNSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKSKTKVGSINLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDSKSANPVFGMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKPGFQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRASLLRGTLTRRSGRVCRGMARARRSTRRKARMVMASWGDRMAMRSSRRKRKKVKIKVWIRIPKRYEMKRRLEITPWTIVPRMGKWKPNQTMRKTIWKMACNKLLHFKLPIFFFQ", "length": 1191, "header": "tr|A0AAA9S0L5-1|E1BE33_BOVIN Computationally mapped isoform of Zinc finger E-box-binding homeobox 2 OS=Bos taurus OX=9913 GN=ZEB2 PE=3 SV=1 CANONICAL=E1BE33-1" }, "locus": { "chromosome": "2", "start_pos": 52305538, "end_pos": 52176980, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120176.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120176.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076856.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076856.1" } ] } }, { "isoform_ac": "A0AAA9S258-1", "url": "https://www.uniprot.org/uniprotkb/E1BE33/entry#A0AAA9S258-1", "sequence": { "sequence": "MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKPQIAEEDGIANPLDQERSPASVPNHESSPHVSQALLPREEEEDEIREGGVEHAWHNSDILQASVDGPVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGALGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERNSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKSKTKVGSINLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDSKSANPVFGMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKPGFQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM", "length": 1190, "header": "tr|A0AAA9S258-1|E1BE33_BOVIN Computationally mapped isoform of Zinc finger E-box-binding homeobox 2 OS=Bos taurus OX=9913 GN=ZEB2 PE=3 SV=1 CANONICAL=E1BE33-1" }, "locus": { "chromosome": "2", "start_pos": 52305495, "end_pos": 52176980, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096126.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096126.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079983.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079983.1" } ] } }, { "isoform_ac": "A0AAA9SAU2-1", "url": "https://www.uniprot.org/uniprotkb/E1BE33/entry#A0AAA9SAU2-1", "sequence": { "sequence": "MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKPQIAEEDGIANPLDQERSPASVPNHESSPHVSQALLPREEEEDEIREGGVEHAWHNSDILQASVDGPEEMKEDYDTMGPEATIQTTVNNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSDSCLGRRLQLLPHQKEKKKITLILIVILGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGALGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERNSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKSKTKVGSINLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDSKSANPVFGMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKPGFQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFS7-1", "uniprot_ac": "E1BFS7", "uniprot_id": "E1BFS7_BOVIN", "mass": { "chemical_mass": 54160.0, "monoisotopic_mass": 54160.0 }, "refseq": { "ac": "XP_005221005", "name": "ETS translocation variant 4 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221005" }, "gene_names": [ { "name": "ETV4", "type": "recommended", "evidence": [ { "id": "E1BFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ] }, { "name": "ETV4", "type": "synonym", "evidence": [ { "id": "XP_005221005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221005" } ] } ], "protein_names": [ { "name": "ETS translocation variant 4 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005221005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221005" } ] }, { "name": "ETS variant transcription factor 4", "type": "synonym", "evidence": [ { "id": "E1BFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFS7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ETV4", "url": "https://www.uniprot.org/uniprotkb/E1BFS7", "locus": { "chromosome": "19", "start_pos": 43446917, "end_pos": 43462826, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008333", "url": "https://www.ensembl.org/id/ENSBTAG00000008333" } ] } } ], "crossref": [ { "id": "E1BFS7", "url": "https://alphafold.ebi.ac.uk/entry/E1BFS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008333", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008333", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "533129", "url": "https://www.ncbi.nlm.nih.gov/gene/533129", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:533129", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533129", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DPCVPYL", "url": "https://omabrowser.org/oma/group/DPCVPYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFS7", "url": "https://www.orthodb.org/?gene=E1BFS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5687128", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005221005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221005", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RZX5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZX5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJN0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJN0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NR32", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NR32-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFS7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERRMKGGYLDQQVPYTFCSKSPGNGSLREALTVPQGKLMDPGSLPPPDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDPPRQIAIKSPAPGAPGQSPLQAFPRAEQRNFLRSSSTSQPHPGHGYLGEHSSIFQQPLDVCHSFTPSQGAGREPLPAPYQHQLSEPCPPYPQQSFKQEYLDPLYEQAGQPAVGQGGVSGHRYPGAGVVIKQEQTDFSYDSDVPGYASMYLHTEGFSGPSPGDRTVGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGMGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY", "length": 485, "header": "tr|E1BFS7-1|E1BFS7_BOVIN Isoform 1 of ETS variant transcription factor 4 OS=Bos taurus OX=9913 GN=ETV4 PE=3 SV=3 CANONICAL=E1BFS7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RZX5-1", "url": "https://www.uniprot.org/uniprotkb/E1BFS7/entry#A0AAA9RZX5-1", "sequence": { "sequence": "MERRMKGGYLDQQVPYTFCSKSPGNGSLREALTVPQGKLMDPGSLPPPDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSSIFQQPLDVCHSFTPSQGAGREPLPAPYQHQLSEPCPPYPQQSFKQEYLDPLYEQAGQPAVGQGGVSGHRYPGAGVVIKQEQTDFSYDSDVPGYASMYLHTEGFSGPSPGDRTVGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGMGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY", "length": 431, "header": "tr|A0AAA9RZX5-1|E1BFS7_BOVIN Computationally mapped isoform of ETS variant transcription factor 4 OS=Bos taurus OX=9913 GN=ETV4 PE=3 SV=1 CANONICAL=E1BFS7-1" }, "locus": { "chromosome": "19", "start_pos": 43461988, "end_pos": 43447921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111285.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111285.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079156.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079156.1" } ] } }, { "isoform_ac": "A0AAA9TJN0-1", "url": "https://www.uniprot.org/uniprotkb/E1BFS7/entry#A0AAA9TJN0-1", "sequence": { "sequence": "MYLHTEGFSGPSPGDRTVGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGMGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY", "length": 207, "header": "tr|A0AAA9TJN0-1|E1BFS7_BOVIN Computationally mapped isoform of ETS variant transcription factor 4 OS=Bos taurus OX=9913 GN=ETV4 PE=3 SV=1 CANONICAL=E1BFS7-1" }, "locus": { "chromosome": "19", "start_pos": 43449549, "end_pos": 43447921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095046.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095046.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096457.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096457.1" } ] } }, { "isoform_ac": "A0ABI0NR32-1", "url": "https://www.uniprot.org/uniprotkb/E1BFS7/entry#A0ABI0NR32-1", "sequence": { "sequence": "MQLPGPCPPAPSQHHPSLLSCLFPPAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDPPRQIAIKSPAPGAPGQSPLQAFPRAEQRNFLRSSSTSQPHPGHGYLGEHSSIFQQPLDVCHSFTPSQGAGREPLPAPYQHQLSEPCPPYPQQSFKQEYLDPLYEQAGQPAVGQGGVSGHRYPGAGVVIKQEQTDFSYDSDVPGYASMYLHTEGFSGPSPGDRTVGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGMGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY", "length": 443, "header": "tr|A0ABI0NR32-1|A0ABI0NR32_BOVIN Computationally mapped isoform of ETS variant transcription factor 4 OS=Bos taurus OX=9913 GN=ETV4 PE=3 SV=1 CANONICAL=E1BFS7-1" }, "locus": { "chromosome": "19", "start_pos": 43459486, "end_pos": 43447921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153844.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153844.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105971.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105971.1" } ] } }, { "isoform_ac": "E1BFS7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFS7/entry#E1BFS7-1", "sequence": { "sequence": "MERRMKGGYLDQQVPYTFCSKSPGNGSLREALTVPQGKLMDPGSLPPPDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDPPRQIAIKSPAPGAPGQSPLQAFPRAEQRNFLRSSSTSQPHPGHGYLGEHSSIFQQPLDVCHSFTPSQGAGREPLPAPYQHQLSEPCPPYPQQSFKQEYLDPLYEQAGQPAVGQGGVSGHRYPGAGVVIKQEQTDFSYDSDVPGYASMYLHTEGFSGPSPGDRTVGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGMGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY", "length": 485, "header": "tr|E1BFS7-1|E1BFS7_BOVIN Isoform 1 of ETS variant transcription factor 4 OS=Bos taurus OX=9913 GN=ETV4 PE=3 SV=3 CANONICAL=E1BFS7-1" }, "locus": { "chromosome": "19", "start_pos": 43461988, "end_pos": 43447921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010973.6", "url": "https://www.ensembl.org/id/ENSBTAT00000010973.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010973.5", "url": "https://www.ensembl.org/id/ENSBTAP00000010973.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:533129", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533129", "resource": "KEGG Pathway" }, { "id": "R-BTA-5687128", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5687128", "resource": "Reactome", "description": "MAPK6/MAPK4 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JX95-1", "protein_name": "ETS variant transcription factor 4", "gene_name": "Etv4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSQKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLSYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFSRAEPQQSLLRASSSSQSHPGHGYLGEHSSVFQQPVDMCHAFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAASQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSAPSSGDGVMGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNHRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGHKGGYSY", "length": 487 }, "evidence": [ { "id": "E1BFS7", "url": "https://omabrowser.org/oma/group/E1BFS7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P28322-1", "protein_name": "ETS translocation variant 4", "gene_name": "Etv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENSFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFSRAEQQQSLLRASSSSQSHPGHGYLGEHSSVFQQPVDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQNFKQEYHDPLYEQAGQPASSQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVMGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGIGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELTGPAPPFGHRGGYSY", "length": 485 }, "evidence": [ { "id": "E1BFS7", "url": "https://omabrowser.org/oma/group/E1BFS7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P43268-1", "protein_name": "ETS translocation variant 4", "gene_name": "ETV4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY", "length": 484 }, "evidence": [ { "id": "E1BFS7", "url": "https://omabrowser.org/oma/group/E1BFS7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" }, { "name": "positive regulation of keratinocyte differentiation", "id": "GO:0045618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045618", "evidence": [ { "database": "UniProtKB", "id": "E1BFS7", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFS7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 485, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFS7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFS7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFS7" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 342, "end_pos": 422, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG95-1", "uniprot_ac": "E1BG95", "uniprot_id": "E1BG95_BOVIN", "mass": { "chemical_mass": 59755.0, "monoisotopic_mass": 59755.0 }, "refseq": { "ac": "XP_005222645", "name": "upstream-binding protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222645" }, "gene_names": [ { "name": "UBP1", "type": "recommended", "evidence": [ { "id": "E1BG95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG95" } ] }, { "name": "UBP1", "type": "synonym", "evidence": [ { "id": "XP_005222645", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222645" } ] } ], "protein_names": [ { "name": "Upstream-binding protein 1", "type": "recommended", "evidence": [ { "id": "E1BG95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG95/entry#names_and_taxonomy" } ] }, { "name": "upstream-binding protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005222645", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222645" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG95", "url": "https://www.uniprot.org/uniprotkb/E1BG95" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UBP1", "url": "https://www.uniprot.org/uniprotkb/E1BG95", "locus": { "chromosome": "22", "start_pos": 7648953, "end_pos": 7712993, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003968", "url": "https://www.ensembl.org/id/ENSBTAG00000003968" } ] } } ], "crossref": [ { "id": "E1BG95", "url": "https://alphafold.ebi.ac.uk/entry/E1BG95", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003968", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003968", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09588", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09588", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "785419", "url": "https://www.ncbi.nlm.nih.gov/gene/785419", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:785419", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785419", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THINQVY", "url": "https://omabrowser.org/oma/group/THINQVY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BG95", "url": "https://www.orthodb.org/?gene=E1BG95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11037:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11037:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005222645", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222645", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S2C7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2C7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2C7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG95", "url": "https://www.uniprot.org/uniprotkb/E1BG95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG95-1", "url": "https://www.uniprot.org/uniprotkb/E1BG95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDDETKHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDVPEITGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREKMEKRAAHEKEKYQPSYDTTVLTEMRLEPIIEDAVEHEQKKSSKRTLPADYGDSLAKRGSCSPWPDTPTAYVNNSPSAAPTFTSPPPSACSVPDSNSSSPNHQGDGIPQASSELQPSATIQETQQWLLKNRFSSYTRLFSNFLGADLLKLTKEDLVQICGAADGIRLYNSLKSRSVRPRLTLYVCREQPAPQGQQPAAGGGESGSATPFVYHAIYLEEMVASEVARKLALVFNIPFHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAENGGGVHIILK", "length": 535, "header": "tr|E1BG95-1|E1BG95_BOVIN Isoform 1 of Upstream-binding protein 1 OS=Bos taurus OX=9913 GN=UBP1 PE=3 SV=3 CANONICAL=E1BG95-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S2C7-1", "url": "https://www.uniprot.org/uniprotkb/E1BG95/entry#A0AAA9S2C7-1", "sequence": { "sequence": "MAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDDETKHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDVPEITGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREKMEKRAAHEKEKYQPSYDTTVLTECSPWPDTPTAYVNNSPSAAPTFTSPPPSACSVPDSNSSSPNHQGDGIPQASSEQLQPSATIQETQQWLLKNRFSSYTRLFSNFLGADLLKLTKEDLVQICGAADGIRLYNSLKSRSVRPRLTLYVCREQPAPQGQQPAAGGGESGSATPFVYHAIYLEEMVASEVARKLALVFNIPFHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAENGGGVHIILK", "length": 500, "header": "tr|A0AAA9S2C7-1|E1BG95_BOVIN Computationally mapped isoform of Upstream-binding protein 1 OS=Bos taurus OX=9913 GN=UBP1 PE=3 SV=1 CANONICAL=E1BG95-1" }, "locus": { "chromosome": "22", "start_pos": 7712124, "end_pos": 7649957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101318.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101318.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080063.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080063.1" } ] } }, { "isoform_ac": "E1BG95-1", "url": "https://www.uniprot.org/uniprotkb/E1BG95/entry#E1BG95-1", "sequence": { "sequence": "MAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDDETKHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDVPEITGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREKMEKRAAHEKEKYQPSYDTTVLTEMRLEPIIEDAVEHEQKKSSKRTLPADYGDSLAKRGSCSPWPDTPTAYVNNSPSAAPTFTSPPPSACSVPDSNSSSPNHQGDGIPQASSELQPSATIQETQQWLLKNRFSSYTRLFSNFLGADLLKLTKEDLVQICGAADGIRLYNSLKSRSVRPRLTLYVCREQPAPQGQQPAAGGGESGSATPFVYHAIYLEEMVASEVARKLALVFNIPFHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAENGGGVHIILK", "length": 535, "header": "tr|E1BG95-1|E1BG95_BOVIN Isoform 1 of Upstream-binding protein 1 OS=Bos taurus OX=9913 GN=UBP1 PE=3 SV=3 CANONICAL=E1BG95-1" }, "locus": { "chromosome": "22", "start_pos": 7712124, "end_pos": 7649957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005181.8", "url": "https://www.ensembl.org/id/ENSBTAT00000005181.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005181.6", "url": "https://www.ensembl.org/id/ENSBTAP00000005181.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:785419", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785419", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LKN3-1", "protein_name": "Upstream-binding protein 1", "gene_name": "Ubp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWVLSMDEVIESGLVHDFDSSLSGIGQELGAGAYSMSDVLALPIFKQEDSSLSLEAEAKHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDVPEISGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKNDREKMEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADYGDSLAKRGSCSPWPDTPTAYVNNSPSPAPTFTSSQQSTCSVPDSNSSSPNHQGDGVAQASGEQIQPSATTQETQQWLLKNRFSSYTRLFSNFSGADLLKLTKEDLVQICGAADGIRLYNSLKSRSVRPRLTIYVCQEQPSSAVPQGQPQAAGSGGEGGAGTPCVYHAIYLEEMVASEVARKLASVFNIPFHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAENNDGIHIILK", "length": 540 }, "evidence": [ { "id": "E1BG95", "url": "https://omabrowser.org/oma/group/E1BG95/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A3KPT8-1", "protein_name": "Upstream-binding protein 1", "gene_name": "ubp1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWVLKMDDATIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDVSVPVESDTKNPPFQYVMCAATSPAVKLHEETLTYLNQGQSYEIRMLDNRKKGEMPELNKIVKSIVRVVFHDRRLQYMEHQQLEGWKWNRPGDRLLDIDIPMSVGITEAQAHPSQLNAAEFLWDLSKRASVFVQVHCISTEFTPRKHGGEKGVPFRIQIDTFKQDESGEYIEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTPQEKEKYQPSYDTTILSETRLEPVMEEVVELELKKSSKRTLPADCGDSIAKSKRGSCSPWPDNAYVNPITAATPTFTSTTNTYSSSSTVPDSESSSPNHQGDLGNLTVVESLSPTASIQDTQKWLLKNRFNSYSRVFAHFSGSDLLKLTREDLVQICGAADGIRLYNALKSRAVRPRLTLYVSLEASQSESPLLEKRGRSKNGEHSSPAAIPVYHALYLEEMTACELTRKISSVLALPLTHISQVYKQGPTGIHILLSDQMVYNFLDESSFIISIIQDDSNDGFHLVLK", "length": 544 }, "evidence": [ { "id": "E1BG95", "url": "https://omabrowser.org/oma/group/E1BG95/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q811S7-1", "protein_name": "Upstream-binding protein 1", "gene_name": "Ubp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWVLSMDEVIESGLVHDFDSSLSGIGQELGAGAYSMSDVLALPIFKQEDSSLSLEDEAKHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDMPELSGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKNDREKMEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADYGDSLAKRGSCSPWPDTPTAYVNNSPSPAPTFTSSQPSTCSVPDSNSSSPNHQGDGAAQASGEQIQPSATTQETQQWLLKNRFSSYTRLFSNFSGADLLKLTKEDLVQICGAADGIRLYNSLKSRSVRPRLTIYVCQEQPSSTALQGQPQAAGSGGESGGGTPSVYHAIYLEEMVASEVARKLASVFNIPFHQINQVYRQGPTGIHILVSDQMVQNFQDETCFLFSTVKAENNDGIHIILK", "length": 540 }, "evidence": [ { "id": "E1BG95", "url": "https://omabrowser.org/oma/group/E1BG95/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZI7-1", "protein_name": "Upstream-binding protein 1", "gene_name": "UBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDGETEHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDMPEINGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADYGDSLAKRGSCSPWPDAPTAYVNNSPSPAPTFTSPQQSTCSVPDSNSSSPNHQGDGASQTSGEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSGADLLKLTKEDLVQICGAADGIRLYNSLKSRSVRPRLTIYVCREQPSSTVLQGQQQAASSASENGSGAPYVYHAIYLEEMIASEVARKLALVFNIPLHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAESSDGIHIILK", "length": 540 }, "evidence": [ { "id": "E1BG95", "url": "https://omabrowser.org/oma/group/E1BG95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BG95", "url": "https://www.uniprot.org/uniprotkb/E1BG95" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BG95", "url": "https://www.uniprot.org/uniprotkb/E1BG95" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BG95", "url": "https://www.uniprot.org/uniprotkb/E1BG95" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BG95", "url": "https://www.uniprot.org/uniprotkb/E1BG95" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BG95", "url": "https://www.uniprot.org/uniprotkb/E1BG95" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BG95", "url": "https://www.uniprot.org/uniprotkb/E1BG95" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BG95", "url": "https://www.uniprot.org/uniprotkb/E1BG95" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BG95", "url": "https://www.uniprot.org/uniprotkb/E1BG95" } ], "pmid": "" }, { "name": "negative regulation of viral transcription", "id": "GO:0032897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032897", "evidence": [ { "database": "UniProtKB", "id": "E1BG95", "url": "https://www.uniprot.org/uniprotkb/E1BG95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BG95-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 535, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BG95-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BG95" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BG95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG95" }, { "id": "PS51968", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51968" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Grh/CP2 DB", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 296, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 322, "end_pos": 324 }, { "start_pos": 345, "end_pos": 347 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"monoisotopic_mass": 59536.0 }, "refseq": { "ac": "NP_001179333", "name": "MSL complex subunit 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179333" }, "gene_names": [ { "name": "MSL3", "type": "recommended", "evidence": [ { "id": "E1BFW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFW0" } ] }, { "name": "MSL3L1", "type": "synonym", "evidence": [ { "id": "NP_001179333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179333" } ] }, { "name": "MSL3", "type": "synonym", "evidence": [ { "id": "NP_001179333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179333" } ] } ], "protein_names": [ { "name": "MSL complex subunit 3", "type": "recommended", "evidence": [ { "id": "E1BFW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFW0/entry#names_and_taxonomy" } ] }, { "name": "MSL complex subunit 3", "type": "synonym", "evidence": [ { "id": "NP_001179333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179333" } ] }, { "name": "Male-specific lethal 3 homolog", "type": "synonym", "evidence": [ { "id": "E1BFW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFW0/entry#names_and_taxonomy" } ] }, { "name": "Male-specific lethal-3 homolog 1", "type": "synonym", "evidence": [ { "id": "E1BFW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFW0/entry#names_and_taxonomy" } ] }, { "name": "Male-specific lethal-3 protein-like 1", "type": "synonym", "evidence": [ { "id": "E1BFW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFW0/entry#names_and_taxonomy" } ] }, { "name": "male-specific lethal 3-like 1", "type": "synonym", "evidence": [ { "id": "NP_001179333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179333" } ] } ], "function": [ { "annotation": "Non-catalytic component of the MSL histone acetyltransferase complex, a multiprotein complex that mediates the majority of histone H4 acetylation at 'Lys-16' (H4K16ac), an epigenetic mark that prevents chromatin compaction. The MSL complex is required for chromosome stability and genome integrity by maintaining homeostatic levels of H4K16ac. The MSL complex is also involved in gene dosage by promoting up-regulation of genes expressed by the X chromosome. X up-regulation is required to compensate for autosomal biallelic expression. The MSL complex also participates in gene dosage compensation by promoting expression of Tsix non-coding RNA. Acts as a histone reader that specifically recognizes and binds histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex. May play a role X inactivation in females.", "evidence": [ { "database": "UniProtKB", "id": "E1BFW0", "url": "https://www.uniprot.org/uniprotkb/E1BFW0#function" }, { "database": "UniProtKB", "id": "ARBA00059382", "url": "https://www.uniprot.org/uniprotkb/ARBA00059382#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFW0", "url": "https://www.uniprot.org/uniprotkb/E1BFW0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MSL3", "url": "https://www.uniprot.org/uniprotkb/E1BFW0", "locus": { "chromosome": "X", "start_pos": 131750626, "end_pos": 131766122, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009278", "url": "https://www.ensembl.org/id/ENSBTAG00000009278" } ] } } ], "crossref": [ { "id": "E1BFW0", "url": "https://alphafold.ebi.ac.uk/entry/E1BFW0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009278", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009278", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18983", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18983", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "515220", "url": "https://www.ncbi.nlm.nih.gov/gene/515220", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515220", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515220", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DTEYAHL", "url": "https://omabrowser.org/oma/group/DTEYAHL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFW0", "url": "https://www.orthodb.org/?gene=E1BFW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10880:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10880:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05712", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05712", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22732", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22732", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3214847", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214847", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179333", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179333", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S2M9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2M9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFW0", "url": "https://www.uniprot.org/uniprotkb/E1BFW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFW0-1", "url": "https://www.uniprot.org/uniprotkb/E1BFW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLAKKAVARLRSTGRKRKRCRLPGVDSVLKSLPADEKDENDENSISSSSDSEEKDGEISEEGDTEEKTEVKEGPELHTKKEMEERTITIEIPDVLKKKLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVIPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQVQYKKVTSSKFFLPIKESTTSTNRNQEELSPSPPLLNPSTPQSTESQPTSGEPTTPKRRKGEPEAFQSLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPVPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLVPDSYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 520, "header": "tr|E1BFW0-1|E1BFW0_BOVIN Isoform 1 of MSL complex subunit 3 OS=Bos taurus OX=9913 GN=MSL3 PE=4 SV=1 CANONICAL=E1BFW0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S2M9-1", "url": "https://www.uniprot.org/uniprotkb/E1BFW0/entry#A0AAA9S2M9-1", "sequence": { "sequence": "MKTMKTKEGPELHTKKEMEERTITIEIPDVLKKKLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVIPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQVQYKKVTSSKFFLPIKESTTSTNRNQEELSPSPPLLNPSTPQSTESQPTSGEPTTPKRRKGEPEAFQSLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPVPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLVPDSYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 372, "header": "tr|A0AAA9S2M9-1|E1BFW0_BOVIN Computationally mapped isoform of MSL complex subunit 3 OS=Bos taurus OX=9913 GN=MSL3 PE=4 SV=1 CANONICAL=E1BFW0-1" }, "locus": { "chromosome": "X", "start_pos": 131763745, "end_pos": 131751337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119683.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119683.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077557.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077557.1" } ] } }, { "isoform_ac": "E1BFW0-1", "url": "https://www.uniprot.org/uniprotkb/E1BFW0/entry#E1BFW0-1", "sequence": { "sequence": "MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLAKKAVARLRSTGRKRKRCRLPGVDSVLKSLPADEKDENDENSISSSSDSEEKDGEISEEGDTEEKTEVKEGPELHTKKEMEERTITIEIPDVLKKKLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVIPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQVQYKKVTSSKFFLPIKESTTSTNRNQEELSPSPPLLNPSTPQSTESQPTSGEPTTPKRRKGEPEAFQSLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPVPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLVPDSYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 520, "header": "tr|E1BFW0-1|E1BFW0_BOVIN Isoform 1 of MSL complex subunit 3 OS=Bos taurus OX=9913 GN=MSL3 PE=4 SV=1 CANONICAL=E1BFW0-1" }, "locus": { "chromosome": "X", "start_pos": 131766078, "end_pos": 131751337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030541.5", "url": "https://www.ensembl.org/id/ENSBTAT00000030541.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030520.4", "url": "https://www.ensembl.org/id/ENSBTAP00000030520.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515220", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515220", "resource": "KEGG Pathway" }, { "id": "R-BTA-3214847", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214847", "resource": "Reactome", "description": "HATs acetylate histones" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PS75-1", "protein_name": "MSL complex subunit 3", "gene_name": "MSL3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTSRGMKFKFHRGERVLCFEPDPTKAKVLYDAKIVDIIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLARKAVARMRRKGRKKRRCRLPGVDSVLKSLPAEENDHNSEKTVSSSSDDSDEGTDEEIKSEESDIEERTEMKEDQDTHSKREMEERAINIEIPEVLKKKLEEDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERSRHHQVTPHANMNLHYVPPEKNVELCKEMVDGLRITFDFTLPLILLYPYEQAQFKKVTSSKFFLPIKENSTNTNRNQEELSPSPPLLNPPTPQSTDSQPATAEPATPKRRKAEPEILQSLRRSTRHTSNCDRLSESSASPQPKRRHLETPTSMPKLFLHLEKKTPVHSGSSSPITLTPSKEGSAVFTGFEGRRNNELNEVLSWKLMPENYPPSDQPPPPSYIYGSQHLLRMFVKLPEILGKMCFPDKNLKALVKHFEMFLRFLAEYHDDFFPESAYVAACEAYYSTKNPRAIY", "length": 522 }, "evidence": [ { "id": "E1BFW0", "url": "https://omabrowser.org/oma/group/E1BFW0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8I6A9H7-1", "protein_name": "MSL complex subunit 3", "gene_name": "Msl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSASKGMKFQFHSGEKVLCFEPDPTKARVLYDAKIIDVIIGKDEKGRKIPEYLIHFNGWNSSSWDRWAAEDHVLHDTDENRRLQRKLAKKAIARLRGTGKKKRRCRLPGVDSVLKSVPVKEKTKNDENSISSTCHESCGEKNGGIKEHRQRRIKVKTKGKKKVLSLRSRKDMDERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHAMMHAHMNVHYVPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQTQYKRVTSSKFFLPIKESTTTTNRSQEELSPSPPLLNPSTPQSTESQPPTGEPATPKRRKAEPEALQSLRRSTRHSTNCDRLSESSSSPQPKRRQQDTSTSMPKLFLHLEKKTPVHSRSSSPIPLTPSKDGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 526 }, "evidence": [ { "id": "E1BFW0", "url": "https://omabrowser.org/oma/group/E1BFW0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HH51-1", "protein_name": "MSL complex subunit 3", "gene_name": "Msl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSASEGMKFQFHSGEKVLCFEPDATKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWNSSWDRWASEDHVLHDTDENRRLQRKLAKKAIARLRGAGGKKRRCRLPGVDSVLKSVPVKETTQNDENSISSTCHDSSGEKNEEIKEHRQRRIKVKTKAKKKVLSLRSRKDMDERTITIDIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHAMMHAHMNVHYVPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKCFLPIKESTTTTNRSQEELSPSPPLLNPSTPQSTESQPLSGEPATPKRRKADPEALQSLRRSTRHSTNCDRLSESSSSPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSFIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 525 }, "evidence": [ { "id": "E1BFW0", "url": "https://omabrowser.org/oma/group/E1BFW0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8N5Y2-1", "protein_name": "MSL complex subunit 3", "gene_name": "MSL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 521 }, "evidence": [ { "id": "E1BFW0", "url": "https://omabrowser.org/oma/group/E1BFW0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WVG9-1", "protein_name": "MSL complex subunit 3", "gene_name": "Msl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSASEGMKFQFHSGEKVLCFEPDPTKARVLYDAKIIDVIIGKDEKGRKIPEYLIHFNGWNRSWDRWAAEEHVLHDTDENRRLQRKLAKKAIARLRGTGKKKRRCRLPGVDSVLKSVPVKEKSKNDENSVSSTCHESCGEKNGGIKEHRQRRIKVKAKAKKKVLSLRSRKEMDERTITIDIPDVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHAMMHTHMNVHYVPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQTQYKRVTSSKFFLPIKESTTTTNRSQEELSPSPPLLNPSTPQSTESQPPTGEPATPKRRKAEPEALQSLRRSTRHSTNCDRLSESSSSPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKDGSAVFAGFEGRRPNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 525 }, "evidence": [ { "id": "E1BFW0", "url": "https://omabrowser.org/oma/group/E1BFW0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BFW0", "url": "https://www.uniprot.org/uniprotkb/E1BFW0" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "E1BFW0", "url": "https://www.uniprot.org/uniprotkb/E1BFW0" } ], "pmid": "" }, { "name": "MSL complex", "id": "GO:0072487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072487", "evidence": [ { "database": "UniProtKB", "id": "E1BFW0", "url": "https://www.uniprot.org/uniprotkb/E1BFW0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BFW0", "url": "https://www.uniprot.org/uniprotkb/E1BFW0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BFW0", "url": "https://www.uniprot.org/uniprotkb/E1BFW0" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "E1BFW0", "url": "https://www.uniprot.org/uniprotkb/E1BFW0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E1BFW0", "url": "https://www.uniprot.org/uniprotkb/E1BFW0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BFW0", "url": "https://www.uniprot.org/uniprotkb/E1BFW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFW0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 520, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFW0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFW0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFW0" }, { "id": "SM00298", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00298" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromo", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 90, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIJ5-1", "uniprot_ac": "E1BIJ5", "uniprot_id": "E1BIJ5_BOVIN", "mass": { "chemical_mass": 198570.0, "monoisotopic_mass": 198570.0 }, "refseq": { "ac": "XP_024849315", "name": "NEDD4-binding protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849315" }, "gene_names": [ { "name": "N4BP2", "type": "recommended", "evidence": [ { "id": "E1BIJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5" } ] }, { "name": "N4BP2", "type": "synonym", "evidence": [ { "id": "XP_024849315", "database": "RefSeq", "url": 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"strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000175", "url": "https://www.ensembl.org/id/ENSBTAG00000000175" } ] } } ], "crossref": [ { "id": "ENSBTAG00000000175", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000175", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14365", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14365", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539533", "url": "https://www.ncbi.nlm.nih.gov/gene/539533", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": 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"Protein Classification", "Other" ] }, { "id": "PF08590", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08590", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13671", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25124", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25124", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25126", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25126", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28512", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28512", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024849315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849315", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S3X3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3X3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZ26", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZ26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZ26-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZ26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIJ5", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIJ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRRRKNLGGNPFRKTTNSKEVVSSVTSHEEPTTTLPSVYETKVDQEELFTSVSEMFSDLDPDVVYLMLSECDFKVENAMDCLLELSATDAKIEESSSTNFIASEKQVNAVKCEIMEKCPPKEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDNQAYSFLPLQDVNNFSDPSSFVSSDSSNMTPILSTQNMDLNNENLELSVSALSSNSLTSHSVSNGSKSFTKDNTVALEDSLLSSSLNADNDTLMDGSNQIQKELSESECVKTQFSQAPVDLDANELQAPLNLAVQNPGIGLIGTGGDQKSTSVPDVFVPSEEFSFQPHKHTELPPKGKDVNYCPVLTPLPLLLPPPPPPPMWNPMIPAFDLFQANHGFVAPVVTTAAHWRPVNYAFPPPVISHASPTKVWRSKEGASAYQVQEAPVSQAVRKKTSSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYINGQYQFDVRYLGEAHEWNQNRAKEAFEKKVSPVIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGISKEKITRMLEHYQRFVSVPIIMSSSVPEKIERIELCAYSCDRSTSPRDNEDITSEKEENVLSSSLKHLELTEEKKLDVTKENMLPENIAYLPNADLNKGKKEISDMNPNIQNAFIQEAPNTYFPDSESEVQVTDKSEKEEPVEMALEKECSETNADSLLERMSPSSCYGENNQGDCGLSNPVPNQNEKSLSSEILEERAAVKKKAFGKQKSKSTLEKFPKHELSFVGDWPVDKTIGQRTKRNRKMEKASSVQNDKKYNRPQSHKILDNSLSVSVDCMQPQGPPYENVEDDDRSQCGDASEPFSSCEYDTYKNPERDSFNIVGDWPSLDSLAQREHRSRIPKAGLNEPSLEFGTNSSMNEISLYSSHEACWGTSPEELKTLGGCTRGSSEMLPNEMTYESKTCPSKKIHREHTLSLPYINSVPTVPEKIGPQTLAEFSEEKTKEVPEIGVGMCTQTEPQDFALLWKVEKNKISVSDSLRVLTGRLDGFKPKTFNINTKLDVQEAIPYRVMYDKSTYVEESELTNADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTEFENIKKSYDEAQIGPFSLGLNLKEIISQRGSLEDSNFSVPEFSHGIDINNTNVQSTCNSKKENLEQAEIRAITTEKHGLVTSILPTVELNNSNEVLANSQTELSGLYNVKQFFPDTLKATTTKTVSEMEKNSEVAETGGNIPSSLNLSDILNSVSSTSNLELHEETYFTNSFEINKNENLPKDYVKFPNTEEFMIEEEQEMETILMAGSALSAGVTGEDKAETLNPTPVTTKSLTIDCLELALPPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWKESVMERQRQEEVSCGKLMQDPSLFGHIGLDNSEQKSSQRTGKKLLKTLAAPEMLPLLDHWNTQTKKVSLREIMSEEIALQEKHDLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHNYSLEHTVQFLNCVLEGDPVKTVVAQEFVHQNENITSHTAQKSKEKKAKKLKETEDIPSEPSFQDFEYPEYDDYRAEAFLHQQKRMECYSKAKEAYRMGKKNVATFYAQQGSLHEQKMKEANHLAAVEIFEKVNASLLPQNVLDLHGLHVDEAIEHLTTVLQQKTEEFKQNGGKPYLSVITGRGNHSQGGVARIKPAVIKYLTSHNFRFSEIKPGCLKVMLK", "length": 1767, "header": "tr|E1BIJ5-1|E1BIJ5_BOVIN Isoform 1 of NEDD4 binding protein 2 OS=Bos taurus OX=9913 GN=N4BP2 PE=4 SV=3 CANONICAL=E1BIJ5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S3X3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5/entry#A0AAA9S3X3-1", "sequence": { "sequence": "MPRRRKNLGGNPFRKTTNSKEVVSSVTSHEEPTTTLPSVYETKVDQEELFTSVSEMFSDLDPDVVYLMLSECDFKVENAMDCLLELSATDAKIEESSSTNFIASEKQVNAVKCEIMEKCPPKEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDNQAYSFLPLQDVNNFSDPSSFVSSDSSNMTPILSTQNMDLNNENLELSVSALSSNSLTSHSVSNGSKSFTKDNTVALEDSLLSSSLNADNDTLMDGSNQIQKELSESECVKTQFSQAPVDLDANELQAPLNLAVQNPGIGLIGTGGDQKSTSVPDVFVPSEEFSFQPHKHTELPPKGKDVNYCPVLTPLPLLLPPPPPPPMWNPMIPAFDLFQANHGFVAPVVTTAAHWRPVNYAFPPPVISHASPTKVWRSKEGASAYQVQEAPVSQAVRKKTSSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYINGQYQFDVRYLGEAHEWNQNRAKEAFEKKVSPVIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGISKEKITRMLEHYQRFVSVPIIMSSSVPEKIERIELCAYSCDRSTSPRDNEDITSEKEENVLSSSLKHLELTEEKKLDVTKENMLPENIAYLPNADLNKGKKEISDMNPNIQNAFIQEAPNTYFPDSESEVQVTDKSEKEEPVEMALEKECSETNADSLLERMSPSSCYGENNQGDCGLSNPVPNQNEKSLSSEILEERAAVKKKAFGKQKSKSTLEKFPKHELSFVGDWPVDKTIGQRTKRNRKMEKASSVQNDKKYNRPQSHKILDNSLSVSVDCMQPQGPPYENVEDDDRSQCGDASEPFSSCEYDTYKNPERDSFNIVGDWPSLDSLAQREHRSRIPKAGLNEPSLEFGTNSSMNEISLYSSHEACWGTSPEELKTLGGCTRGSSEMLPNEMTYESKTCPSKKIHREHTLSLPYINSVPTVPEKIGPQTLAEFSEEKTKEVPEIGVGMCTQTEPQDFALLWKVEKNKISVSDSLRVLTGRLDGFKPKTFNINTKLDVQEAIPYRVMYDKSTYVEESELTNADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTEFENIKKSYDEAQIGPFSLGLNLKEIISQRGSLEDSNFSVPEFSHGIDINNTNVQSTCNSKKENLEQAEIRAITTEKHGLVTSILPTVELNNSNEVLANSQTELSGLYNVKQFFPDTLKATTTKTVSEMEKNSEVAETGGNIPSSLNLSDILNSVSSTSNLELHEETYFTNSFEINKNENLPKDYVKFPNTEEFMIEEEQEMETILMAGSALSAGVTGEDKAETLNPTPVTTKSLTIDCLELALPPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWKESVMERQRQEEVSCGKLMQDPSLFGHIGLDNSEQKSSQRTGKKLLKTLAAPEMLPLLDHWNTQTKKVSLREIMSEEIALQEKHDLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHNYSLEHTVQFLNCVLEGDPVKTVVAQEFVHQNENITSHTAQKSKEKKYIMLSRECCCCCC", "length": 1605, "header": "tr|A0AAA9S3X3-1|E1BIJ5_BOVIN Computationally mapped isoform of NEDD4 binding protein 2 OS=Bos taurus OX=9913 GN=N4BP2 PE=4 SV=1 CANONICAL=E1BIJ5-1" }, "locus": { "chromosome": "6", "start_pos": 59146876, "end_pos": 59108267, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119273.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119273.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078498.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078498.1" } ] } }, { "isoform_ac": "A0AAA9SZ26-1", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5/entry#A0AAA9SZ26-1", "sequence": { "sequence": "MPRRRKNLGGNPFRKTTNSKEVVSSVTSHEEPTTTLPSVYETKVDQEELFTSVSEMFSDLDPDVVYLMLSECDFKVENAMDCLLELSATDAKIEESSSTNFIASEKQVNAVKCEIMEKCPPKEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDNQAYSFLPLQDVNNFSDPSSFVSSDSSNMTPILSTQNMDLNNENLELSVSALSSNSLTSHSVSNGSKSFTKDNTVALEDSLLSSSLNADNDTLMDGSNQIQKELSESECVKTQFSQAPVDLDANELQAPLNLAVQNPGIGLIGTGGDQKSTSVPDVFVPSEEFSFQPHKHTELPPKGKDVNYCPVLTPLPLLLPPPPPPPMWNPMIPAFDLFQANHGFVAPVVTTAAHWRPVNYAFPPPVISHASPTKVWRSKEGASAYQVQEAPVSQAVRKKTSSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYINGQYQFDVRYLGEAHEWNQNRAKEAFEKKVSPVIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGISKEKITRMLEHYQRFVSVPIIMSSSVPEKIERIELCAYSCDRSTSPRDNEDITSEKEENVLSSSLKHLELTEEKKLDVTKENMLPENIAYLPNADLNKGKKEISDMNPNIQNAFIQEAPNTYFPDSESEVQVTDKSEKEEPVEMALEKECSETNADSLLERMSPSSCYGENNQGDCGLSNPVPNQNEKSLSSEILEERAAVKKKAFGKQKSKSTLEKFPKHELSFVGDWPVDKTIGQRTKRNRKMEKASSVQNDKKYNRPQSHKILDNSLSVSVDCMQPQGPPYENVEDDDRSQCGDASEPFSSCEYDTYKNPERDSFNIVGDWPSLDSLAQREHRSRIPKAGLNEPSLEFGTNSSMNEISLYSSHEACWGTSPEELKTLGGCTRGSSEMLPNEMTYESKTCPSKKIHREHTLSLPYINSVPTVPEKIGPQTLAEFSEEKTKEVPEIGVGMCTQTEPQDFALLWKVEKNKISVSDSLRVLTGRLDGFKPKTFNINTKLDVQEAIPYRVMYDKSTYVEESELTNADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTEFENIKKSYDEAQIGPFSLGLNLKEIISQRGSLEDSNFSVPEFSHGIDINNTNVQSTCNSKKENLEQAEIRAITTEKHGLVTSILPTVELNNSNEVLANSQTELSGLYNVKQFFPDTLKATTTKTVSEMEKNSEVAETGGNIPSSLNLSDILNSVSSTSNLELHEETYFTNSFEINKNENLPKDYVKFPNTEEFMIEEEQEMETILMAGSALSAGVTGEDKAETLNPTPVTTKSLTIDCLELALPPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWKESVMERQRQEEVSCGKLMQDPSLFGHIGLDNSEQKSSQRTGKKLLKTLAAPEMLPLLDHWNTQTKKVSLREIMSEEIALQEKHDLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHNYSLEHTVQFLNCVLEGDPVKTVVAQEFVHQNENITSHTAQKSKEKKAKKLKETEDIPSEPSFQDFEYPEYDDYRAEAFLHQQKRMECYSKAKEAYRMGKKNVATFYAQQGSLHEQKMKEANHLAAVEIFEKVNASLLPQNVLDLHGLHVDEAIEHLTTVLQQKTEVFWAFPLVLR", "length": 1721, "header": "tr|A0AAA9SZ26-1|E1BIJ5_BOVIN Computationally mapped isoform of NEDD4 binding protein 2 OS=Bos taurus OX=9913 GN=N4BP2 PE=4 SV=2 CANONICAL=E1BIJ5-1" }, "locus": { "chromosome": "6", "start_pos": 59196482, "end_pos": 59108267, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135596.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135596.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090643.2", "url": "https://www.ensembl.org/id/ENSBTAP00000090643.2" } ] } }, { "isoform_ac": "E1BIJ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5/entry#E1BIJ5-1", "sequence": { "sequence": "MPRRRKNLGGNPFRKTTNSKEVVSSVTSHEEPTTTLPSVYETKVDQEELFTSVSEMFSDLDPDVVYLMLSECDFKVENAMDCLLELSATDAKIEESSSTNFIASEKQVNAVKCEIMEKCPPKEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDNQAYSFLPLQDVNNFSDPSSFVSSDSSNMTPILSTQNMDLNNENLELSVSALSSNSLTSHSVSNGSKSFTKDNTVALEDSLLSSSLNADNDTLMDGSNQIQKELSESECVKTQFSQAPVDLDANELQAPLNLAVQNPGIGLIGTGGDQKSTSVPDVFVPSEEFSFQPHKHTELPPKGKDVNYCPVLTPLPLLLPPPPPPPMWNPMIPAFDLFQANHGFVAPVVTTAAHWRPVNYAFPPPVISHASPTKVWRSKEGASAYQVQEAPVSQAVRKKTSSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYINGQYQFDVRYLGEAHEWNQNRAKEAFEKKVSPVIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGISKEKITRMLEHYQRFVSVPIIMSSSVPEKIERIELCAYSCDRSTSPRDNEDITSEKEENVLSSSLKHLELTEEKKLDVTKENMLPENIAYLPNADLNKGKKEISDMNPNIQNAFIQEAPNTYFPDSESEVQVTDKSEKEEPVEMALEKECSETNADSLLERMSPSSCYGENNQGDCGLSNPVPNQNEKSLSSEILEERAAVKKKAFGKQKSKSTLEKFPKHELSFVGDWPVDKTIGQRTKRNRKMEKASSVQNDKKYNRPQSHKILDNSLSVSVDCMQPQGPPYENVEDDDRSQCGDASEPFSSCEYDTYKNPERDSFNIVGDWPSLDSLAQREHRSRIPKAGLNEPSLEFGTNSSMNEISLYSSHEACWGTSPEELKTLGGCTRGSSEMLPNEMTYESKTCPSKKIHREHTLSLPYINSVPTVPEKIGPQTLAEFSEEKTKEVPEIGVGMCTQTEPQDFALLWKVEKNKISVSDSLRVLTGRLDGFKPKTFNINTKLDVQEAIPYRVMYDKSTYVEESELTNADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTEFENIKKSYDEAQIGPFSLGLNLKEIISQRGSLEDSNFSVPEFSHGIDINNTNVQSTCNSKKENLEQAEIRAITTEKHGLVTSILPTVELNNSNEVLANSQTELSGLYNVKQFFPDTLKATTTKTVSEMEKNSEVAETGGNIPSSLNLSDILNSVSSTSNLELHEETYFTNSFEINKNENLPKDYVKFPNTEEFMIEEEQEMETILMAGSALSAGVTGEDKAETLNPTPVTTKSLTIDCLELALPPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWKESVMERQRQEEVSCGKLMQDPSLFGHIGLDNSEQKSSQRTGKKLLKTLAAPEMLPLLDHWNTQTKKVSLREIMSEEIALQEKHDLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHNYSLEHTVQFLNCVLEGDPVKTVVAQEFVHQNENITSHTAQKSKEKKAKKLKETEDIPSEPSFQDFEYPEYDDYRAEAFLHQQKRMECYSKAKEAYRMGKKNVATFYAQQGSLHEQKMKEANHLAAVEIFEKVNASLLPQNVLDLHGLHVDEAIEHLTTVLQQKTEEFKQNGGKPYLSVITGRGNHSQGGVARIKPAVIKYLTSHNFRFSEIKPGCLKVMLK", "length": 1767, "header": "tr|E1BIJ5-1|E1BIJ5_BOVIN Isoform 1 of NEDD4 binding protein 2 OS=Bos taurus OX=9913 GN=N4BP2 PE=4 SV=3 CANONICAL=E1BIJ5-1" }, "locus": { "chromosome": "6", "start_pos": 59159321, "end_pos": 59108267, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000200.8", "url": "https://www.ensembl.org/id/ENSBTAT00000000200.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000200.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000200.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A4H4-1", "protein_name": "NEDD4-binding protein 2-like 2", "gene_name": "N4bp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIVSASQPGNILVLEVRMPRKRKNVGGNPLRKTANSKKSVVSRVASREEPTTTLPSMCETKIDQEELFTSISEMFSALDPDVVYLMLSECDFKVESAMDCLLELSAANAKMEASPSQTSAARERRLRASGGTVTGTRRPEDETEDSKLDSFLDMQLTEDLDSLIQNAFEKLNSPPDDQVYPFSPLQDANSFNDPSTFVNSDSSGMTSLPSVQNTGSNSEIVKSSAALLGSNPLTSHSVLNEPESCAQSSTLALEEGYLEDSPLGSSSNPANDSVMGCGNFSQRQKDHLESECPSVQHSQALVSVGNSEPQVPSNRSLHNSGSDLPSTDGDQKSTSAPDVFVPSEGFSFKPHKHPELPPKGKDMNYCPVLTPLPLLLPPPPPPPIWNPMIPAFDLFQGNHGFVAPVVTTAAHWRPVNYTFPPPIISHTSPTKVWRGSEGASAYQVQEAPVSQPARKKTTSYVGLVLVLLRGLPGSGKSFLARTLQEDNPGGVILSTDDYFYINGQYQFDVKYLGEAHEWNQNRAKEAFEKKVSPVIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGVSKEKISRMLEHYQRFVSVPIIMSSSDPEKTERIELCAYACEDRNSSPRDSEAVTSTKEENVSSASPKHLDLTEEKTLEVATQAVLPSSEPPLPPTSLNRGRKELGDGSHSVHGHFIQEDPSTYFPNAEGSVQAPDRSEKEQEVVSAKERSEADAWSPAEGASSNGHCVEGDQEASEFASAATLPRENPSPPEILEERTAGKKKTIGKQKSKSSLEKPKPELSNFVGDWPVDKTISQRTKRNRKTEKGSSVQNDKKCNRPQSHKVLDTRVSVNTDPIQPQGSPHGNDDPSEVPSNYHYDPYKSTEQTSFSTVSDWPSSASLAQREHRSRMPKAGLSEPNVEFGTNDKLGEIPLYPAHEAYWGTSPEELKTLSSNLRSSEVLPSKTAHEHHQTPLSQMVPGQHTLPLPFPSSAATLPGVVGPRALTEFPVGVSGIVSGVDTGTCTQTEPQDFALLWKIEKNKISVSDSVRVLTGRVDGFKPKDFTLNRKLNVQETIPYRVMHDKSTFVEESELTNADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDAEVVNPPESYSESQVGPFSMGLDLKEIISHRGTSEGSNSCVSEFSPGIGIRNTSAQSDGDPEKGNSEQEGIRAINPENPESVARIFPNATVNVKSSNGMAPDLSGAYTFKQPLSLTPRSYVPKDVSEIEKSLVTETRDNIHSFLNLSDIINSATSTSNPELNEDVYLTGSLEVKKNENLPKDYVKFANMEEFINEDKQEMEKSLMPGTGWSAGVSEESKPEVSTPAPVAAKSLTIDCLELTLPPELAFQLNELFGPVGVDSGSLTVEDCVVHIDLNLAKVIHEKWRESVMERQRQEEVSLGKRMQDPSLAGHTVLDNSEQKSSQKTGKRLLKTLAAPETLDHWNTQTKKVSLREIMSEEIALQEKHDLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLADIFKDHNYSLENTVQFLNCVLEGDPVKTVIAQECAHQNESNTSHSAQKSKEKKAKKPKEADDTAGDPSFQDFEYPEYDDYRAEAFLHQQKRMECYSKAKEAYRMGKKNVATFYAQQGSLHEQKMREANHLAAVEIFEKVNASLLPQNVLDLHGLHVDEAIEHLTAVLQQKTEEFKQSGGKPYLSVITGRGNHSQGGVARIKPAVIKYLTSHSFRFSEIKPGCLKVMLK", "length": 1777 }, "evidence": [ { "id": "E1BIJ5", "url": "https://omabrowser.org/oma/group/E1BIJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VQG7-1", "protein_name": "NEDD4-binding protein 2-like 2", "gene_name": "N4bp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDCLLELSATDAKGAESSAQTSGDRDSKPGAAGNSVMETCHPEGEGEDSKLDSFLDMQLTEDLDSLIQNAFEKLNSPPDDQVYPFSPLQDANSFNDPSTFMNSDSSGMTSLLSVQSTSSNSETLKSSASLPGSNPPTSHSVLNAPESCAKLALEGGYSEGSPLSSSGNPTNGSVRGCGNFSQRQKDLSESECPSAQHSQALADLGNSDPQAPSTHPLHNSGSDLPGTDGDQKSASAPDVFVPSEGFNFKPHKHPELPPKGKDMNYCPVLTPLPLLLPPPPPPPIWNPMIPAFDLFQGNHGFVAPVVTTAAHWRPVNYTFPPPIISHNSPTKVWRGGEGASAYQVQEAPASQPVRKKATSFVGLVLVLLRGLPGSGKSFLARTLQEDNPGGVILSTDDYFYINGQYQFDVKYLGEAHEWNQNRAKEAFEKKVSPVIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGVSKEKISRMLEHYQRFVSVPIIMSSSDPEKTERIELCAYASDDSPRDSEAISSAKEDSVSSASPKHSELTEEKTLEVATQAVLSVRDPQLPCPGLNRGRKELGDVSHGGHNPFFQEAPSTYFPNPESKGQATDRSEEEQEMVSEKEHCEADAWRPAGGASSDGRCADDNQEACGSAGAAALPGETPSPPEMLEERTAGKKKTIGKQKGKSSLEKIPKQELSNFVGDWPVDKTISQRTKRNRKTEKGLSVQSDKKGNLPQSHKVLDARVSVNTDPVQPQGSSHGNDDLSEVPSSYHYDPYRSTEQSSLSAVSDWPSSASLAPREHRPRMPKADLSEPSVEFGTNDNLGEIPLYPAHEAYWGTSPEELKTLSSSLRSSEMLPSQTAPEHHPTSLNPLAHSQHALPLTFPSSAAALPGVVGPRSLTEFPVGVSGIVSGVDTGTCTQTEPQDFALLWKIEKNKINVSDSVRVLTGRLDGFKPKDFTLNRKVNVQETIPYRVMHDKSTFVEESELTSADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTAVESSPKSYSESQVGPFSMGLDLKEIISHRGTSEGSNSSVSEFSPGIGIRNTSARSAGNPGKGTSEQEGRRAMNPENPELITRVFPNAAVKVKSNNETLPDRQAELPGAYTFKQPLSLTPRSYIPKDVSEIEKNLVMTETRDNMHSFLNLSDIINSATSTSNPELNEDVYLTGSLEVKKNENLPKDYVKFANMEEFINEDKQEMEKNLMPGSGWSAGVSEEGKAEVLTPTPVTATSLTIDCLELALPPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWRESVMERQRQEEVSRGKRTQDPLLAGHTGLDNFEQKSSQKTGKRLLKTLAAPETLDHWNTQTKKVSLREIMSEEIALQEKHDLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHSYSLENTVQFLNCVLEGDPVKTVVAQECVHQNENNTYTAQKSKEKKAKKPKEAEDSPGDPSFQDFEYPEYDDYRAEAFLHQQKRMECYSKAKEAYRMGKKNVATFYAQQGSLHEQKMKEANHLAAVEIFEKVNASLLPQNVLDLHGLHVDEAIEHLTAVLQQKTEEFKQSGGKPYLSVITGRGNHSQGGVARIKPAVIKYLTSHSFRFSEIKPGCLKVMLK", "length": 1678 }, "evidence": [ { "id": "E1BIJ5", "url": "https://omabrowser.org/oma/group/E1BIJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86UW6-1", "protein_name": "NEDD4-binding protein 2", "gene_name": "N4BP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "E1BIJ5", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5" } ], "pmid": "" }, { "name": "DNA endonuclease activity", "id": "GO:0004520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004520", "evidence": [ { "database": "UniProtKB", "id": "E1BIJ5", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nuclear-transcribed mRNA catabolic process, non-stop decay", "id": "GO:0070481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070481", "evidence": [ { "database": "UniProtKB", "id": "E1BIJ5", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BIJ5", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1170, "end_pos": 1172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1183, "end_pos": 1185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1224, "end_pos": 1226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1280, "end_pos": 1282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1546, "end_pos": 1548, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1579, "end_pos": 1581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1679, "end_pos": 1681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1730, "end_pos": 1732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 913, "end_pos": 915, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5" }, { "id": "PS51140", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51140" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUE", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 88, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BIJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIJ5" }, { "id": "PS50828", "database": 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"id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192526", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192526", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S4M8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S4M8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZA1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZA1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3A9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3A9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGV8", "url": "https://www.uniprot.org/uniprotkb/E1BGV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGV8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMNKNKLIHEFLEVVSRGDVELICDHIAKVHSILGNLDFQHPKTGNTPLITAAEENLTEVVGFLLEKGADITLCNYSNQTAVHVANCDVQRQLLAINGIQAPQMQLLQSSWQGDLEQLQHLLASEEFLDINFPNQHGLTPLMLAVRDVDLFERLDMLTLYRPAEVLSELLRHHADPKLCDFSGKSAIHYVSQIESFRKQQLLDILMNSMPKPERHAESLLDICHDTNSSPTDMMTVTKNQNIILQSIGSSEESDQDDDCSHSILISEEGDPSGDGQDWQPRTEGVEIIVTFPRDVIHPQEMGQEELPENNQITSEHQEWTPAHSVSLPKNIEMVGFRTKMVTTEPLLAKKEERSQELFNMNLGFLLPRPHLETIISKSVARDVPHFLKGQPRKSEEFSISDMKYSSRRIEFSLPPLSCLPMRSGLLTIPLSHKDQKARERNMPRLVSFIPKFSEPISQSDEFRPSNKQKEAPIKMLADQTLRSFDGSIWSRNMCSFWKAHRHRQHLEKEASRKSKEREGCVNIEVFHFEKGQSLVSLENFKEGSFPTGREEDTDCHGNELRRAEENAPSLSSGKKGDSGARNYEQDSEVGYTKPIKFQEALPSDIGLSQDEGTKSDKADSKSASALKGEAIELDHISEDYTLRKSLSDAVTDGPIEKLSEDHSSMETSTKISVAETTKPGMNGTVPLIHITFPGDETPKEPAITKPSLQKRKGILRSNSSLNILAHQENDRHKVKTQRNKLDSKTKTSNRTPQNFMISTEVSVKPTTHKTSIKTQVFPALGLVDPRPWQPPKFQRRMPQTERKQSAYQALKPKKPSFPCLYKNPGIEKSSVPLSAQPAEPRLNYLDLKYSDMFKEINSTANGPGIYEMFGTPVYCHMREAERHENKYHREICSASSGRCITNKCRSSHSERSSNSRNRLSQKRPHSKPPKSSLGIKQKHRSLISKEKDFQAVGSTLQDAENGDGISETGWQIKSSGNDFLSLKDEVQPMNLVQAHEQFTEQNDFFPVSDLSIVEEVSMEESADEEDISNNQILATRLRDLHQLEELRHQTPFVLSENSWAVPSEKSSNMHVLQEEQKVASPGETNANQILTNNVDFDSFSDKSKTLRSFSSQEKQESVTSQAYQHWALFLDHDSLTNESIPYQTLGKTLNEADSISQEILDSVKNEELTDELLGCLAAELLALDEKDDNSCQIMADETDPESRDFVLSKRGNTMQELGRETTNVKIQRYSNGFRRYDKEERFFNPHEKKTFSENSLKYEESILWTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSDKLATVKEYQKLQEEVDLLKALKHVNIVAYLGTCLEENILSIFMEFVPGGSISSIINRFGPLPEMVFCKYTEQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDCFSENAADFVRACLTRDQHERPSAVQLLKHSFLKRNH", "length": 1531, "header": "tr|E1BGV8-1|E1BGV8_BOVIN Isoform 1 of Mitogen-activated protein kinase kinase kinase 19 OS=Bos taurus OX=9913 GN=MAP3K19 PE=3 SV=3 CANONICAL=E1BGV8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S4M8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGV8/entry#A0AAA9S4M8-1", "sequence": { "sequence": "MMNKNKLIHEFLEVVSRGDVELICDHIAKVHSILGNLDFQHPKTGNTPLITAAEENLTEVVGFLLEKGADITLCNYSNQTAVHVANCDVQRQLLAINGIQAPQMQLLQSSWQGDLEQLQHLLASEEFLDINFPNQHGLTPLMLAVRDVDLFERLDMLTLYRPAEVLSELLRHHADPKLCDFSGKSAIHYVSQIESFRKQQLLDILMNSMPKPERHAESLLDICHDTNSSPTDMMTVTKNQNIILQSIGSSEESDQDDDCSHSILISEEGDPSGDGQDWQPRTEGVEIIVTFPRDVIHPQEMGQEELPENNQITSEHQEWTPAHSVSLPKNIEMVGFRTKMVTTEPLLAKKEERSQELFNMNLGFLLPRPHLETIISKSVARDVPHFLKGQPRKSEEFSISDMKYSSRRIERYSNGFRRYDKEERFFNPHEKKTFSENSLKYEESILWTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSDKLATVKEYQKLQEEVDLLKALKHVNIVAYLGTCLEENILSIFMEFVPGGSISSIINRFGPLPEMVFCKYTEQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDCFSENAADFVRACLTRDQHERPSAVQLLKHSFLKRNH", "length": 714, "header": "tr|A0AAA9S4M8-1|E1BGV8_BOVIN Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 19 OS=Bos taurus OX=9913 GN=MAP3K19 PE=3 SV=1 CANONICAL=E1BGV8-1" }, "locus": { "chromosome": "2", "start_pos": 62313294, "end_pos": 62259568, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098516.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098516.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077091.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077091.1" } ] } }, { "isoform_ac": "A0AAA9SZA1-1", "url": "https://www.uniprot.org/uniprotkb/E1BGV8/entry#A0AAA9SZA1-1", "sequence": { "sequence": "MMNKNKLIHEFLEVVSRGDVELICDHIAKVHSILGNLDFQHPKTGNTPLITAAEENLTEVVGFLLEKGADITLCNYSNQTAVHVANCDVQRQLLAINGIQAPQMQLLQSSWQGDLEQLQHLLASEEFLDINFPNQHGLTPLMLAVRDVDLFERLDMLTLYRPAEVLSELLRHHADPKLCDFSGKSAIHYVSQIESFRKQQLLDILMNSMPKPERHAESLLDICHDTNSSPTDMMTVTKNQNIILQSIGSSEESDQDDDCSHSILISEEGDPSGDGQDWQPRTEEFSISDMKYSSRRIEFSLPPLSCLPMRSGLLTIPLSHKDQKARERNMPRLVSFIPKFSEPISQSDEFRPSNKQKEAPIKMLADQTLRSFDGSIWSRNMCSFWKAHRHRQHLEKEASRKSKEREGCVNIEVFHFEKGQSLVSLENFKEGSFPTGREEDTDCHGNELRRAEENAPSLSSGKKGDSGARNYEQDSEVGYTKPIKFQEALPSDIGLSQDEGTKSDKADSKSASALKGEAIELDHISEDYTLRKSLSDAVTDGPIEKLSEDHSSMETSTKISVAETTKPGMNGTVPLIHITFPGDETPKEPAITKPSLQKRKGILRSNSSLNILAHQENDRHKVKTQRNKLDSKTKTSNRTPQNFMISTEVSVKPTTHKTSIKTQVFPALGLVDPRPWQPPKFQRRMPQTERKQSAYQALKPKKPSFPCLYKNPGIEKSSVPLSAQPAEPRLNYLDLKYSDMFKEINSTANGPGIYEMFGTPVYCHMREAERHENKYHREICSASSGRCITNKCRSSHSERSSNSRNRLSQKRPHSKPPKSSLGIKQKHRSLISKEKDFQAVGSTLQDAENGDGISETGWQIKSSGNDFLSLKDEVQPMNLVQAHEQFTEQNDFFPVSDLSIVEEVSMEESADEEDISNNQILATRLRDLHQLEELRHQTPFVLSENSWAVPSEKSSNMHVLQEEQKVASPGETNANQILTNNVDFDSFSDKSKTLRSFSSQEKQESVTSQAYQHWALFLDHDSLTNESIPYQTLGKTLNEADSISQEILDSVKNEELTDELLGCLAAELLALDEKDDNSCQIMADETDPESRDFVLSKRGNTMQELGRETTNVKIQRYSNGFRRYDKEERFFNPHEKKTFSENSLKYEESILWTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSDKLATVKEYQKLQEEVDLLKALKHVNIVAYLGTCLEENILSIFMEFVPGGSISSIINRFGPLPEMVFCKYTEQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDCFSENAADFVRACLTRDQHERPSAVQLLKHSFLKRNH", "length": 1419, "header": "tr|A0AAA9SZA1-1|E1BGV8_BOVIN Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 19 OS=Bos taurus OX=9913 GN=MAP3K19 PE=3 SV=1 CANONICAL=E1BGV8-1" }, "locus": { "chromosome": "2", "start_pos": 62313294, "end_pos": 62259568, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132536.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132536.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088694.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088694.1" } ] } }, { "isoform_ac": "A0AAA9T3A9-1", "url": "https://www.uniprot.org/uniprotkb/E1BGV8/entry#A0AAA9T3A9-1", "sequence": { "sequence": "MMNKNKLIHEFLEVVSRGDVELICDHIAKVHSILGNLDFQHPKTGNTPLITAAEENLTEVVGFLLEKGADITLCNYSNQTAVHVANCDVQRQLLAINGIQAPQMQLLQSSWQGDLEQLQHLLASEEFLDINFPNQHGLTPLMLAVRDVDLFERLDMLTLYRPAEVLSELLRHHADPKLCDFSGKSAIHYVSQIESFRKQQLLDILMNSMPKPERHAESLLDICHDTNSSPTDMMTVTKNQNIILQSIGSSEESDQDDDCSHSILISEEGDPSGDGQDWQPRTEGVEIIVTFPRDVIHPQEMGQEELPENNQITSEHQEWTPAHSVSLPKNIEMVGFRTKMVTTEPLLAKKEERSQELFNMNLGFLLPRPHLETIISKSVARDVPHFLKGQPRKSEEFSISDMKYSSRRIEVYCGLTSQGQLIAVKQVALDTSDKLATVKEYQKLQEEVDLLKALKHVNIVAYLGTCLEENILSIFMEFVPGGSISSIINRFGPLPEMVFCKYTEQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDCFSENAADFVRACLTRDQHERPSAVQLLKHSFLKRNH", "length": 664, "header": "tr|A0AAA9T3A9-1|E1BGV8_BOVIN Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 19 OS=Bos taurus OX=9913 GN=MAP3K19 PE=3 SV=1 CANONICAL=E1BGV8-1" }, "locus": { "chromosome": "2", "start_pos": 62313294, "end_pos": 62259568, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090721.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090721.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090967.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090967.1" } ] } }, { "isoform_ac": "E1BGV8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGV8/entry#E1BGV8-1", "sequence": { "sequence": "MMNKNKLIHEFLEVVSRGDVELICDHIAKVHSILGNLDFQHPKTGNTPLITAAEENLTEVVGFLLEKGADITLCNYSNQTAVHVANCDVQRQLLAINGIQAPQMQLLQSSWQGDLEQLQHLLASEEFLDINFPNQHGLTPLMLAVRDVDLFERLDMLTLYRPAEVLSELLRHHADPKLCDFSGKSAIHYVSQIESFRKQQLLDILMNSMPKPERHAESLLDICHDTNSSPTDMMTVTKNQNIILQSIGSSEESDQDDDCSHSILISEEGDPSGDGQDWQPRTEGVEIIVTFPRDVIHPQEMGQEELPENNQITSEHQEWTPAHSVSLPKNIEMVGFRTKMVTTEPLLAKKEERSQELFNMNLGFLLPRPHLETIISKSVARDVPHFLKGQPRKSEEFSISDMKYSSRRIEFSLPPLSCLPMRSGLLTIPLSHKDQKARERNMPRLVSFIPKFSEPISQSDEFRPSNKQKEAPIKMLADQTLRSFDGSIWSRNMCSFWKAHRHRQHLEKEASRKSKEREGCVNIEVFHFEKGQSLVSLENFKEGSFPTGREEDTDCHGNELRRAEENAPSLSSGKKGDSGARNYEQDSEVGYTKPIKFQEALPSDIGLSQDEGTKSDKADSKSASALKGEAIELDHISEDYTLRKSLSDAVTDGPIEKLSEDHSSMETSTKISVAETTKPGMNGTVPLIHITFPGDETPKEPAITKPSLQKRKGILRSNSSLNILAHQENDRHKVKTQRNKLDSKTKTSNRTPQNFMISTEVSVKPTTHKTSIKTQVFPALGLVDPRPWQPPKFQRRMPQTERKQSAYQALKPKKPSFPCLYKNPGIEKSSVPLSAQPAEPRLNYLDLKYSDMFKEINSTANGPGIYEMFGTPVYCHMREAERHENKYHREICSASSGRCITNKCRSSHSERSSNSRNRLSQKRPHSKPPKSSLGIKQKHRSLISKEKDFQAVGSTLQDAENGDGISETGWQIKSSGNDFLSLKDEVQPMNLVQAHEQFTEQNDFFPVSDLSIVEEVSMEESADEEDISNNQILATRLRDLHQLEELRHQTPFVLSENSWAVPSEKSSNMHVLQEEQKVASPGETNANQILTNNVDFDSFSDKSKTLRSFSSQEKQESVTSQAYQHWALFLDHDSLTNESIPYQTLGKTLNEADSISQEILDSVKNEELTDELLGCLAAELLALDEKDDNSCQIMADETDPESRDFVLSKRGNTMQELGRETTNVKIQRYSNGFRRYDKEERFFNPHEKKTFSENSLKYEESILWTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSDKLATVKEYQKLQEEVDLLKALKHVNIVAYLGTCLEENILSIFMEFVPGGSISSIINRFGPLPEMVFCKYTEQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDCFSENAADFVRACLTRDQHERPSAVQLLKHSFLKRNH", "length": 1531, "header": "tr|E1BGV8-1|E1BGV8_BOVIN Isoform 1 of Mitogen-activated protein kinase kinase kinase 19 OS=Bos taurus OX=9913 GN=MAP3K19 PE=3 SV=3 CANONICAL=E1BGV8-1" }, "locus": { "chromosome": "2", "start_pos": 62313294, "end_pos": 62259568, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045570.3", "url": "https://www.ensembl.org/id/ENSBTAT00000045570.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042949.3", "url": "https://www.ensembl.org/id/ENSBTAP00000042949.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:538897", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538897", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E1BGV8", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BGV8", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "E1BGV8", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BGV8", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BGV8", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1137, "end_pos": 1139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1420, "end_pos": 1422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1443, "end_pos": 1445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 682, "end_pos": 684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 718, "end_pos": 720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 749, "end_pos": 751, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", 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"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", 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"https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": 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} } ], "crossref": [ { "id": "E1BJ01", "url": "https://alphafold.ebi.ac.uk/entry/E1BJ01", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004187", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004187", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "9FQR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9FQR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ 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"tr|A0AAA9S5V4-1|E1BJ01_BOVIN Computationally mapped isoform of Cilia- and flagella-associated protein 251 OS=Bos taurus OX=9913 GN=CFAP251 PE=1 SV=1 CANONICAL=E1BJ01-1" }, "locus": { "chromosome": "17", "start_pos": 53411724, "end_pos": 53347987, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134160.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134160.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079223.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079223.1" } ] } }, { "isoform_ac": "E1BJ01-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ01/entry#E1BJ01-1", "sequence": { "sequence": "MRASSGVYWIWHHSLLFISFFLKKSGSESKLSLQSEFLETFELPRSPGSQLEFLDLDVTTSGEPLISFPERQPSGELDQRPQDELEEEEGRDLEPERGDLEQEKRERRKEKSVSYISKKSEKESQPKARITKASLVSTATEDILFQRRESANMYPLTMTWSFGWNSSLPVYYLRENQRVLLYASGHTGVIYNVLKNNQYHLQGHPNVISCLCISEDRRWVATADKGPDCLIIIWDSFTGIPVHTIFDSCPRDNGIRAMAMTRDAKYLATISDAEIQKVCIWKWTLAVETPACTLDLPKEYGFQNYLIFNPTNNKELVSNSKTQVIYYTWYPEGGILVHSAPLLTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDIYRPLPSASSSMGFPHIKPCKLVHLQKEGITVLTTVDSYIVTGDIRGNIKFYDHTLSIVNWYSHFKLSSIRSLSFSKTPAAPPAENTNYPPDCTLKSDDFVVRNFIIGTSDASVYHLTVDGTKLEKLFVEPRDAICAISCHPYQPLIAIGSFCGMIKVWDYEQKKYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVYILDAMSLESAISEPFRYSRSSVTHISFSHDSQYMATADVSFTVAVYVVRVKHRRRVWEYLARLRSHRKSIRSILFGVHLDSNEPRLLSLGRDRLLIEYNLLKSYKDHLAVLDIHRTDQGSYPTCMVWYPPLTKELFLLICNSGYKVKLFNSTTKMCRKTLLGPVYGSPIEQIQILPVKSTLELQKRYVVFINRDKVGLQILPVDGNPHKTSALICHPNGVAGMALSYDGCCAFTAGGQDRSVVQWEINLSALEAAVSLGGEDLTPFYGLVSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEGEIEDMFNEIRFSEYVDTGKLTDKINLPDFFKVYLNHRPPFGNTMSGIQQSFDILGFTNSKGEKAIQREDFLNLLHTKGEHMTEEEMTDCFATLFGLNPEGWKSEPAASSVKGSEICLEEELPDEITAEIFTTEILGLTISQDSGQDPRISEAEQSF", "length": 1063, "header": "tr|E1BJ01-1|E1BJ01_BOVIN Isoform 1 of Cilia- and flagella-associated protein 251 OS=Bos taurus OX=9913 GN=CFAP251 PE=1 SV=4 CANONICAL=E1BJ01-1" }, "locus": { "chromosome": "17", "start_pos": 53419567, "end_pos": 53347987, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005477.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005477.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005477.6", "url": "https://www.ensembl.org/id/ENSBTAP00000005477.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structural diversity of axonemes across mammalian motile cilia.", "journal": "Nature", "date": "2025", "authors": "Leung Miguel Ricardo, Sun Chen, Zeng Jianwei, Anderson Jacob R, Niu Qingwei, Huang Wei, Noteborn Willem E M, Brown Alan, Zeev-Ben-Mordehai Tzviya, Zhang Rui", "evidence": [ { "database": "UniProtKB", "id": "E1BJ01", "url": "https://www.uniprot.org/uniprotkb/E1BJ01" } ], "reference": [ { "type": "PubMed", "id": "39743588", "url": "https://glygen.org/publication/PubMed/39743588" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "E1BJ01", "url": "https://www.uniprot.org/uniprotkb/E1BJ01" } ], "pmid": "" }, { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "E1BJ01", "url": "https://www.uniprot.org/uniprotkb/E1BJ01" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "E1BJ01", "url": "https://www.uniprot.org/uniprotkb/E1BJ01" } ], "pmid": "" }, { "name": "axoneme", 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"start_pos": 730, "end_pos": 732 }, { "start_pos": 828, "end_pos": 830 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"https://www.uniprot.org/uniprotkb/E1BI88/entry#names_and_taxonomy" } ] }, { "name": "transcription factor ATOH7", "type": "synonym", "evidence": [ { "id": "XP_010818953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818953" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ATOH7", "url": "https://www.uniprot.org/uniprotkb/E1BI88", "locus": { "chromosome": "28", "start_pos": 24690367, "end_pos": 24694773, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017521", "url": "https://www.ensembl.org/id/ENSBTAG00000017521" } ] } } ], "crossref": [ { "id": "E1BI88", "url": 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"IPR050359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539903", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539903", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WINLHCE", "url": "https://omabrowser.org/oma/group/WINLHCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BI88", "url": "https://www.orthodb.org/?gene=E1BI88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19290:SF99", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19290:SF99", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010818953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818953", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S5X0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5X0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI88-1", "url": "https://www.uniprot.org/uniprotkb/E1BI88-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSCKPCNTAAGARAAPPCAGGAECAGTCAGAGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGSERDWVNLHCEHFGRDHYLPFAGAKLPAETEPYGQRLFGFQPEPFQMAS", "length": 152, "header": "tr|E1BI88-1|E1BI88_BOVIN Isoform 1 of Atonal bHLH transcription factor 7 OS=Bos taurus OX=9913 GN=ATOH7 PE=4 SV=2 CANONICAL=E1BI88-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S5X0-1", "url": "https://www.uniprot.org/uniprotkb/E1BI88/entry#A0AAA9S5X0-1", "sequence": { "sequence": "MKSCKPCNTAAGARAAPPCAGGAECAGTCAGAGRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGSERDWVNLHCEHFGRDHYLPFAGAKLPAETEPYGQRLFGFQPEPFQMAS", "length": 144, "header": "tr|A0AAA9S5X0-1|E1BI88_BOVIN Computationally mapped isoform of Atonal bHLH transcription factor 7 OS=Bos taurus OX=9913 GN=ATOH7 PE=4 SV=1 CANONICAL=E1BI88-1" }, "locus": { "chromosome": "28", "start_pos": 24692622, "end_pos": 24692167, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113759.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113759.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077559.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077559.1" } ] } }, { "isoform_ac": "E1BI88-1", "url": 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], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TLW1-1", "protein_name": "Atonal bHLH transcription factor 7", "gene_name": "ATOH7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKSCKPCNPPAAAGARAAPPCTGGAAECAGTCAGAGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGSERDWVNLHCEHFGRDHYLPFAGAKLPGESEPYGQRLFGFQPESFQMAS", "length": 155 }, "evidence": [ { "id": "E1BI88", "url": "https://omabrowser.org/oma/group/E1BI88/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O57598-1", "protein_name": "Transcription factor ATOH7", "gene_name": "ATOH7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKTCQSSHLDSGVESDIQCRSGSGCVVKCSTERMESAAKRRLAANARERRRMQGLNTAFDRLRKVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERYSTEREWINLHCEHFHPESYHHYTGQKVATDSDPYAQRIFSYHPEHFQIAN", "length": 151 }, "evidence": [ { "id": "E1BI88", "url": "https://omabrowser.org/oma/group/E1BI88/", "database": "OMA" } ], 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"OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "neural retina development", "id": "GO:0003407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003407", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "response to auditory stimulus", "id": "GO:0010996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010996", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "neuron fate commitment", "id": "GO:0048663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048663", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "entrainment of circadian clock by photoperiod", "id": "GO:0043153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043153", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "positive regulation of retinal ganglion cell axon guidance", "id": "GO:1902336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902336", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "sensory organ development", "id": "GO:0007423", 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{ "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "E1BI88", "url": "https://www.uniprot.org/uniprotkb/E1BI88" } ], "pmid": "" }, { "name": "nucleoplasm", "id": 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"recommended", "evidence": [ { "id": "E1BG08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG08" } ] }, { "name": "AIDA", "type": "synonym", "evidence": [ { "id": "NP_001192563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192563" } ] } ], "protein_names": [ { "name": "Axin interactor, dorsalization-associated protein", "type": "recommended", "evidence": [ { "id": "E1BG08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG08/entry#names_and_taxonomy" } ] }, { "name": "Axin interaction partner and dorsalization antagonist", "type": "synonym", "evidence": [ { "id": "E1BG08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG08/entry#names_and_taxonomy" } ] }, { "name": "axin interactor, dorsalization-associated protein", "type": "synonym", "evidence": [ { "id": "NP_001192563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192563" } ] } ], "function": [ { "annotation": "Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.", "evidence": [ { "database": "UniProtKB", "id": "E1BG08", "url": "https://www.uniprot.org/uniprotkb/E1BG08#function" }, { "database": "UniProtKB", "id": "ARBA00059715", "url": "https://www.uniprot.org/uniprotkb/ARBA00059715#function" }, { "database": "UniProtKB", "id": "A0AAA9SGG3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGG3#function" }, { "database": "UniProtKB", "id": "A0AAA9T0T4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0T4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG08", "url": "https://www.uniprot.org/uniprotkb/E1BG08" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AIDA", "url": "https://www.uniprot.org/uniprotkb/E1BG08", "locus": { "chromosome": "16", "start_pos": 26158797, "end_pos": 26205930, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007593", "url": "https://www.ensembl.org/id/ENSBTAG00000007593" } ] } } ], "crossref": [ { "id": "E1BG08", "url": "https://alphafold.ebi.ac.uk/entry/E1BG08", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007593", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007593", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "508353", "url": "https://www.ncbi.nlm.nih.gov/gene/508353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:508353", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KLHAAWC", "url": "https://omabrowser.org/oma/group/KLHAAWC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BG08", "url": "https://www.orthodb.org/?gene=E1BG08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28654", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28654", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28654:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28654:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08910", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08910", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14186", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14186", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S7M7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7M7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7M7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGG3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGG3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T0T4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T0T4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG08", "url": "https://www.uniprot.org/uniprotkb/E1BG08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG08-1", "url": "https://www.uniprot.org/uniprotkb/E1BG08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIKIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE", "length": 306, "header": "tr|E1BG08-1|E1BG08_BOVIN Isoform 1 of Axin interactor, dorsalization-associated protein OS=Bos taurus OX=9913 GN=AIDA PE=3 SV=1 CANONICAL=E1BG08-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S7M7-1", "url": "https://www.uniprot.org/uniprotkb/E1BG08/entry#A0AAA9S7M7-1", "sequence": { "sequence": "MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE", "length": 224, "header": "tr|A0AAA9S7M7-1|E1BG08_BOVIN Computationally mapped isoform of Axin interactor, dorsalization-associated protein OS=Bos taurus OX=9913 GN=AIDA PE=3 SV=1 CANONICAL=E1BG08-1" }, "locus": { "chromosome": "16", "start_pos": 26204958, "end_pos": 26159083, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112613.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112613.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079291.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079291.1" } ] } }, { "isoform_ac": "A0AAA9SGG3-1", "url": "https://www.uniprot.org/uniprotkb/E1BG08/entry#A0AAA9SGG3-1", "sequence": { "sequence": "QPLSCFISLWIYPFWIFHANGIRLARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIKIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE", "length": 292, "header": "tr|A0AAA9SGG3-1|E1BG08_BOVIN Computationally mapped isoform of Axin interactor, dorsalization-associated protein OS=Bos taurus OX=9913 GN=AIDA PE=3 SV=1 CANONICAL=E1BG08-1" }, "locus": { "chromosome": "16", "start_pos": 26198615, "end_pos": 26159083, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123841.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123841.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082774.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082774.1" } ] } }, { "isoform_ac": "A0AAA9T0T4-1", "url": "https://www.uniprot.org/uniprotkb/E1BG08/entry#A0AAA9T0T4-1", "sequence": { "sequence": "TDIFVESRYYPTGRGGQRLARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIKIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE", "length": 287, "header": "tr|A0AAA9T0T4-1|E1BG08_BOVIN Computationally mapped isoform of Axin interactor, dorsalization-associated protein OS=Bos taurus OX=9913 GN=AIDA PE=3 SV=1 CANONICAL=E1BG08-1" }, "locus": { "chromosome": "16", "start_pos": 26205902, "end_pos": 26159083, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116262.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116262.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091296.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091296.1" } ] } }, { "isoform_ac": "E1BG08-1", "url": "https://www.uniprot.org/uniprotkb/E1BG08/entry#E1BG08-1", "sequence": { "sequence": "MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIKIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE", "length": 306, "header": "tr|E1BG08-1|E1BG08_BOVIN Isoform 1 of Axin interactor, dorsalization-associated protein OS=Bos taurus OX=9913 GN=AIDA PE=3 SV=1 CANONICAL=E1BG08-1" }, "locus": { "chromosome": "16", "start_pos": 26204958, "end_pos": 26159083, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009987.5", "url": "https://www.ensembl.org/id/ENSBTAT00000009987.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009987.4", "url": "https://www.ensembl.org/id/ENSBTAP00000009987.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:508353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508353", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S9H0-1", "protein_name": "Axin interactor, dorsalization-associated protein", "gene_name": "AIDA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEIEDDEDEGGAGAGAPDSFPARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIRPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE", "length": 306 }, "evidence": [ { "id": "E1BG08", "url": "https://omabrowser.org/oma/group/E1BG08/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6PBN2-1", "protein_name": "Axin interactor, dorsalization-associated protein", "gene_name": "aida", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDVNKTVQKWHASFKKGTDFDSWGQLVEAIDEYQILARQLQKEVQSSNSHDFTEEQKKTLGKFATCLEMRSAALQCTQSQEEFKLEDLKKLEPIIKNILTYNKDFPFDVQPVPLRKILAPGEEENLDVEEDLDAGTGAGSTPSFTSRLPGSLLPRLPSEPGMTLLTLTIEKIGLKDAGQCIDPYITVSVKDLNGIDLNPVQDTPVATRKEDTYIHFSVDVEIQRHLEKLPKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLNLLTKKPLYLHLNQTLHKD", "length": 303 }, "evidence": [ { "id": "E1BG08", "url": "https://omabrowser.org/oma/group/E1BG08/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C4Q6-1", "protein_name": "Axin interactor, dorsalization-associated protein", "gene_name": "Aida", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEVTRSLLQRWGASLRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPIPLRRILAPGEEENLEFEEDEEGGAGAGPPDSFSARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVERLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQSLHKE", "length": 305 }, "evidence": [ { "id": "E1BG08", "url": "https://omabrowser.org/oma/group/E1BG08/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96BJ3-1", "protein_name": "Axin interactor, dorsalization-associated protein", "gene_name": "AIDA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE", "length": 306 }, "evidence": [ { "id": "E1BG08", "url": "https://omabrowser.org/oma/group/E1BG08/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BG08", "url": "https://www.uniprot.org/uniprotkb/E1BG08" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BG08", "url": "https://www.uniprot.org/uniprotkb/E1BG08" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "E1BG08", "url": "https://www.uniprot.org/uniprotkb/E1BG08" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "E1BG08", "url": "https://www.uniprot.org/uniprotkb/E1BG08" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of protein-containing complex assembly", "id": "GO:0031333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031333", "evidence": [ { "database": "UniProtKB", "id": "E1BG08", "url": "https://www.uniprot.org/uniprotkb/E1BG08" } ], "pmid": "" }, { "name": "negative regulation of JNK cascade", "id": "GO:0046329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046329", "evidence": [ { "database": "UniProtKB", "id": "E1BG08", "url": "https://www.uniprot.org/uniprotkb/E1BG08" } ], "pmid": "" }, { "name": "determination of ventral identity", "id": "GO:0048264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048264", "evidence": [ { "database": "UniProtKB", "id": "E1BG08", "url": "https://www.uniprot.org/uniprotkb/E1BG08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BG08-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 306, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BG08-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BG08" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BG08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG08" }, { "id": "PS51911", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51911" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 Aida-type", "eco_id": "ECO_0000259", "start_pos": 157, "end_pos": 304, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIV2-1", "uniprot_ac": "E1BIV2", "uniprot_id": "E1BIV2_BOVIN", "mass": { "chemical_mass": 61555.0, "monoisotopic_mass": 61555.0 }, "refseq": { "ac": "XP_005209255", "name": "regulator of G-protein signaling 14 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209255" }, "gene_names": [ { "name": "RGS14", "type": "recommended", "evidence": [ { "id": "E1BIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ] }, { "name": "RGS14", "type": "synonym", "evidence": [ { "id": "XP_005209255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209255" } ] } ], "protein_names": [ { "name": "Regulator of G-protein signaling 14", "type": "recommended", "evidence": [ { "id": "E1BIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIV2/entry#names_and_taxonomy" } ] }, { "name": "regulator of G-protein signaling 14 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005209255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209255" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RGS14", "url": "https://www.uniprot.org/uniprotkb/E1BIV2", "locus": { "chromosome": "7", "start_pos": 38871553, "end_pos": 38857779, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008497", "url": "https://www.ensembl.org/id/ENSBTAG00000008497" } ] } } ], "crossref": [ { "id": "E1BIV2", "url": "https://alphafold.ebi.ac.uk/entry/E1BIV2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008497", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008497", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08743", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08743", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17137", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17137", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17139", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17139", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532605", "url": "https://www.ncbi.nlm.nih.gov/gene/532605", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PWAEGHR", "url": "https://omabrowser.org/oma/group/PWAEGHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIV2", "url": "https://www.orthodb.org/?gene=E1BIV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45945:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45945:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02196", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02196", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005209255", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209255", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S9L1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9L1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTY0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTY0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIV2-1", "url": "https://www.uniprot.org/uniprotkb/E1BIV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGKPKHLGVPNGRMVLAVSDGELSSTTGPQGQGEGRGSSLSIHSLPSGPSSPFPTEEQPVASWGLSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAEGRPLREPGSWRPGSPDTTRKKPKLKPGKSLPLGVEELGQLPPAEGRPLRKSFRRELAGGAANTALRRESQGSLNSSASLDLGYLAFASSKSESHRKSLGSSEGENESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLENRITLELEVLALERLVRISAKPTKRLQEALQPILTKHGLSPQQVVLRLPGEKQPLDLEKLVSSVASQRLVLDTLPGVTIPQADDIPPCHSQGGPPRIQDKATNLPPPSLNSLAQVPSSITGKRQTCDIEGLVELLNRVQSCGAHDQRGLLRKEDLVLPEFLQLPAQGPNSQQPPPQVESAAQPKGSASDSTVHSAL", "length": 565, "header": "tr|E1BIV2-1|E1BIV2_BOVIN Isoform 1 of Regulator of G-protein signaling 14 OS=Bos taurus OX=9913 GN=RGS14 PE=4 SV=3 CANONICAL=E1BIV2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S9L1-1", "url": "https://www.uniprot.org/uniprotkb/E1BIV2/entry#A0AAA9S9L1-1", "sequence": { "sequence": "MFLEYLPRARWCSEFSLSIFNFFNYSKPLKSGPLFAASGGTSGKEPACPTGDTRHEGSIPGLGRSPGGGHDNPLQHSCLETPMDRGAWRATVHGATQSWTRLKQLSMYRECQAQRDEVSCPRSQSTNLNSGCLGPSSVLAVSDGELSSTTGPQGQGEGRGSSLSIHSLPSGPSSPFPTEEQPVASWGLSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAEGRPLREPGSWRPGSPDTTRKKPKLKPGKSLPLGVEELGQLPPAEGRPLRKSFRRELAGGAANTALRRESQGSLNSSASLDLGYLAFASSKSESHRKSLGSSEGENESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLENRITLELEVLALERLVRISAKPTKRLQEALQPILTKHGLSPQQVVLRLPGEKQPLDLEKLVSSVASQRLVLDTLPGVTIPQADDIPPCHSQGGPPRIQDKATNLPPPSLNSLAQVPSSITGKRQTCDIEGLVELLNRVQSCGAHDQRGLLRKEDLVLPEFLQLPAQGPNSQQPPPQVESAAQPKGSASDSTVHSAL", "length": 687, "header": "tr|A0AAA9S9L1-1|E1BIV2_BOVIN Computationally mapped isoform of Regulator of G-protein signaling 14 OS=Bos taurus OX=9913 GN=RGS14 PE=4 SV=1 CANONICAL=E1BIV2-1" }, "locus": { "chromosome": "7", "start_pos": 38871044, "end_pos": 38862973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088109.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088109.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081976.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081976.1" } ] } }, { "isoform_ac": "A0AAA9TTY0-1", "url": "https://www.uniprot.org/uniprotkb/E1BIV2/entry#A0AAA9TTY0-1", "sequence": { "sequence": "MCWWLQEVASIWDWLSWKGLWGIWVEMSQQEVGYMCLKLGRCGREKGPRTESEKGKGRLACIDNEEAGGAARKVLAVSDGELSSTTGPQGQGEGRGSSLSIHSLPSGPSSPFPTEEQPVASWGLSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAEGRPLREPGSWRPGSPDTTRKKPKLKPGKSLPLGVEELGQLPPAEGRPLRKSFRRELAGGAANTALRRESQGSLNSSASLDLGYLAFASSKSESHRKSLGSSEGENESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLENRITLELEVLALERLVRISAKPTKRLQEALQPILTKHGLSPQQVVLRLPGEKQPLDLEKLVSSVASQRLVLDTLPGVTIPQADDIPPCHSQGGPPRIQDKATNLPPPSLNSLAQVPSSITGKRQTCDIEGLVELLNRVQSCGAHDQRGLLRKEDLVLPEFLQLPAQGPNSQQPPPQVESAAQPKGSASDSTVHSAL", "length": 623, "header": "tr|A0AAA9TTY0-1|E1BIV2_BOVIN Computationally mapped isoform of Regulator of G-protein signaling 14 OS=Bos taurus OX=9913 GN=RGS14 PE=4 SV=1 CANONICAL=E1BIV2-1" }, "locus": { "chromosome": "7", "start_pos": 38871044, "end_pos": 38863897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106939.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106939.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100842.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100842.1" } ] } }, { "isoform_ac": "E1BIV2-1", "url": "https://www.uniprot.org/uniprotkb/E1BIV2/entry#E1BIV2-1", "sequence": { "sequence": "MPGKPKHLGVPNGRMVLAVSDGELSSTTGPQGQGEGRGSSLSIHSLPSGPSSPFPTEEQPVASWGLSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAEGRPLREPGSWRPGSPDTTRKKPKLKPGKSLPLGVEELGQLPPAEGRPLRKSFRRELAGGAANTALRRESQGSLNSSASLDLGYLAFASSKSESHRKSLGSSEGENESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLENRITLELEVLALERLVRISAKPTKRLQEALQPILTKHGLSPQQVVLRLPGEKQPLDLEKLVSSVASQRLVLDTLPGVTIPQADDIPPCHSQGGPPRIQDKATNLPPPSLNSLAQVPSSITGKRQTCDIEGLVELLNRVQSCGAHDQRGLLRKEDLVLPEFLQLPAQGPNSQQPPPQVESAAQPKGSASDSTVHSAL", "length": 565, "header": "tr|E1BIV2-1|E1BIV2_BOVIN Isoform 1 of Regulator of G-protein signaling 14 OS=Bos taurus OX=9913 GN=RGS14 PE=4 SV=3 CANONICAL=E1BIV2-1" }, "locus": { "chromosome": "7", "start_pos": 38871044, "end_pos": 38857929, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011200.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011200.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011200.6", "url": "https://www.ensembl.org/id/ENSBTAP00000011200.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QIV4-1", "protein_name": "Regulator of G-protein signaling 14", "gene_name": "Rgs14", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPGKPKHLGVPNGRMVLAVSDGELTSTAGSQGQSEGRGSSLSIHSLPSGPSSPFSTEDQPVASWALSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTKQLSQEAHNIYHEFLSSQALSPVNIDRQAWLSEEVLAQPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYQECLLAEAEGRPLREPGSSRLGSPDTSRKKPKLKPGKSLPVGVEELGQLPLAEGPCGRPLRKSFRREMTGGAMNLAPRRESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSAEGESESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLESRITFQLEFANLERVVRISAKPTKRLQEALQPILEKHGLSLEQVVLHRPGEKQLLDLEKLVSSVASQTLVLDILPGAKMREASSTSPCRSQGCLPRTQDKGTHLPPLPPSLLVEDASSSTGKRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPSQRPGSQEAPP", "length": 547 }, "evidence": [ { "id": "E1BIV2", "url": "https://omabrowser.org/oma/group/E1BIV2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1S3D6-1", "protein_name": "Regulator of G-protein signaling 14", "gene_name": "RGS14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKPKHLGVPNGRMVLAVSDGELSSTAGPQGQGEGRGSSLSIHSLPSGPSSPYPTEEQPVASWGLSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFREQQLQIFNLMKFDSYARFVKSPMYRECLLAEAEGRPLREPGSSRLGSPEATRKKPKLKPGKSLPLGVEELGQQPQAEGPGGRPLRKSFRKEQGGAANSALRRESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSSEGESESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLENRITFELELAALERVVRISAKPTKRLQDALQPILAKHGLSPQQVALRLPGEKQPLDLGKLVSSVAAQRLVLDTLPGVKIPEAGDVPPCRSQGGPPRIQDKATHPPSQSLNSLAQTSSSITGKRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPVQGNNSQEAPAQTESAAQPKGAPSDSTAHSAL", "length": 567 }, "evidence": [ { "id": "E1BIV2", "url": "https://omabrowser.org/oma/group/E1BIV2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O08773-1", "protein_name": "Regulator of G protein signaling 14", "gene_name": "Rgs14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGKPKHLGVPNGRMVLAVSDGELTSTSGSQAQGEGRGSSLSIHSLPSGPSSPFSTDEQPVASWAQSFERLLQDPRGLAYFTEFLKKEFSAENVTFWQACERFQQIPASDTKQLAQEAHNIYHEFLSSQALSPVNIDRQAWLSEEVLAQPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYQECLLAEAEGRPLREPGSSHLGSPDTARKKPKLKPGKSLPLGVEELGQLPLAEGRPLRKSFRREMPGGAVNSALRRESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSGEGESESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGKEQKALVLDQDCTVLADQEVRLENRITFQLELVGLERVVRISAKPTKRLQEALQPILAKHGLSLDQVVLHRPGEKQLVDLENLVSSVASQTLVLDTLPDAKTREASSIPPCRSQGCLPRTQTKDSHLPPLSSSLSVEDASGSTGKRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPSQRPGSQEAPP", "length": 544 }, "evidence": [ { "id": "E1BIV2", "url": "https://omabrowser.org/oma/group/E1BIV2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43566-7", "protein_name": "Regulator of G protein signaling 14", "gene_name": "RGS14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGKPKHLGVPNGRMVLAVSDGELSSTTGPQGQGEGRGSSLSIHSLPSGPSSPFPTEEQPVASWALSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAEGRPLREPGSSRLGSPDATRKKPKLKPGKSLPLGVEELGQLPPVEGPGGRPLRKSFRRELGGTANAALRRESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSTEGESESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQALVLDQDCTVLADQEVRLENRITFELELTALERVVRISAKPTKRLQEALQPILEKHGLSPLEVVLHRPGEKQPLDLGKLVSSVAAQRLVLDTLPGVKISKARDKSPCRSQGCPPRTQDKATHPPPASPSSLVKVPSSATGKRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPAQGPSSEETPPQTKSAAQPIGGSLNSTTDSAL", "length": 566 }, "evidence": [ { "id": "E1BIV2", "url": "https://omabrowser.org/oma/group/E1BIV2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97492-1", "protein_name": "Regulator of G protein signaling 14", "gene_name": "Rgs14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGKPKHLGVPNGRMVLAVSDGELTSTAGSQAQGEGRGSSLSIHSLPSGPSSPFSTEEQPVASWAQSFERLLQDPRGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTKQLAQEAHNIYHEFLSSQALSPVNIDRQAWLSEEVLAQPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYQECLLAEAEGRPLREPGSSHLGSPDTARKKPKLKPGKSLPLGVEELGQLPLAEGPCGRPLRKSFRREMTGGAMNSALRRESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSGESESESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLENRITFQLELVGLERVVRISAKPTKRLQEALQPILAKHGLSLDQVVLHRPGEKQPMDLENPVSSVASQTLVLDTPPDAKMSEARSISPCRSQGCLPRTQTKDSHLPPSSSSLLVEDASSSTGNRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPSQRPGSREAPP", "length": 547 }, "evidence": [ { "id": "E1BIV2", "url": "https://omabrowser.org/oma/group/E1BIV2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "GTPase activating protein binding", "id": "GO:0032794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032794", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "GDP-dissociation inhibitor activity", "id": "GO:0005092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005092", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "learning", "id": "GO:0007612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007612", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "negative regulation of G protein-coupled receptor signaling pathway", "id": "GO:0045744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045744", "evidence": [ { "database": "UniProtKB", "id": "E1BIV2", "url": "https://www.uniprot.org/uniprotkb/E1BIV2" } ], "pmid": "" }, { "name": "long-term memory", 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"AF-E1BFF7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 151, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFF7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFF7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF7" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 133, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHJ3-1", "uniprot_ac": "E1BHJ3", "uniprot_id": "E1BHJ3_BOVIN", "mass": { "chemical_mass": 120793.0, "monoisotopic_mass": 120793.0 }, "refseq": { "ac": "NP_001179196", "name": "FERM domain-containing protein 4A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179196" }, "gene_names": [ { "name": "FRMD4A", "type": "recommended", "evidence": [ { "id": "E1BHJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3" } ] }, { "name": "FRMD4A", "type": "synonym", "evidence": [ { "id": "NP_001179196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179196" } ] } ], "protein_names": [ { "name": "FERM domain containing 4A", "type": "synonym", "evidence": [ { "id": "E1BHJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3/entry#names_and_taxonomy" } ] }, { "name": "FERM domain-containing protein 4A", "type": "synonym", "evidence": [ { "id": "NP_001179196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179196" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHJ3", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FRMD4A", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3", "locus": { "chromosome": "13", "start_pos": 28351256, "end_pos": 29032328, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008279", "url": "https://www.ensembl.org/id/ENSBTAG00000008279" } ] } } ], "crossref": [ { "id": "E1BHJ3", "url": "https://alphafold.ebi.ac.uk/entry/E1BHJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008279", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008279", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13191", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13191", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "510714", "url": "https://www.ncbi.nlm.nih.gov/gene/510714", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510714", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510714", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HILTWRT", "url": "https://omabrowser.org/oma/group/HILTWRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHJ3", "url": "https://www.orthodb.org/?gene=E1BHJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46079", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46079", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46079:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46079:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11819", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11819", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179196", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179196", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SAF7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAF7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKL5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKL5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFH0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFH0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TI08", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TI08-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHJ3", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHJ3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGLLGSENLLNAWDRPVWGLTCRALRTCQGRNVRVLQLMLKPWCISRAVYQMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKEEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSSSLQTSPIRSLPHWNSQCSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYVEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGVDEGDAGRLTPSRSQILRTPSLGREGVPDKGAGRAAVSDELRQWYQRSSASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYGDSCFLDSSLYPELADVQWYGQEKAKPGTLV", "length": 1079, "header": "tr|E1BHJ3-1|E1BHJ3_BOVIN Isoform 1 of FERM domain containing 4A OS=Bos taurus OX=9913 GN=FRMD4A PE=4 SV=2 CANONICAL=E1BHJ3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SAF7-1", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3/entry#A0AAA9SAF7-1", "sequence": { "sequence": "MVVQAAVAPNRSQRLLLKIPYGSLRRRSVERMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKEEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSSSLQTSPIRSLPHWNSQCSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYVEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGVDEGDAGRLTPSRSQILRTPSLGREGVPDKGAGRAAVSDELRQWYQRSSASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYGDSCFLDSSLYPELADVQWYGQEKAKPGTLV", "length": 1057, "header": "tr|A0AAA9SAF7-1|E1BHJ3_BOVIN Computationally mapped isoform of FERM domain containing 4A OS=Bos taurus OX=9913 GN=FRMD4A PE=4 SV=1 CANONICAL=E1BHJ3-1" }, "locus": { "chromosome": "13", "start_pos": 28721736, "end_pos": 28352495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103937.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103937.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082320.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082320.1" } ] } }, { "isoform_ac": "A0AAA9SKL5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3/entry#A0AAA9SKL5-1", "sequence": { "sequence": "MAVQLVPDSALSLLMMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKEEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSSSLQTSPIRSLPHWNSQCSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYVEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGVDEGDAGRLTPSRSQILRTPSLGREGVPDKGAGRAAVSDELRQWYQRSSASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGEATENSPIMDGSESPAHQSTDE", "length": 1030, "header": "tr|A0AAA9SKL5-1|E1BHJ3_BOVIN Computationally mapped isoform of FERM domain containing 4A OS=Bos taurus OX=9913 GN=FRMD4A PE=4 SV=1 CANONICAL=E1BHJ3-1" }, "locus": { "chromosome": "13", "start_pos": 29032328, "end_pos": 28364229, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099633.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099633.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084421.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084421.1" } ] } }, { "isoform_ac": "A0AAA9TFH0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3/entry#A0AAA9TFH0-1", "sequence": { "sequence": "MAVQLVPDSALSLLMMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKEEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSSSLQTSPIRSLPHWNSQCSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYVEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGVDEGDAGRLTPSRSQILRTPSLGREGVPDKGAGRAAVSDELRQWYQRSSASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYGDSCFLDSSLYPELADVQWYGQEKAKPGTLV", "length": 1041, "header": "tr|A0AAA9TFH0-1|E1BHJ3_BOVIN Computationally mapped isoform of FERM domain containing 4A OS=Bos taurus OX=9913 GN=FRMD4A PE=4 SV=1 CANONICAL=E1BHJ3-1" }, "locus": { "chromosome": "13", "start_pos": 29032328, "end_pos": 28352495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118089.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118089.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095751.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095751.1" } ] } }, { "isoform_ac": "A0AAA9TI08-1", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3/entry#A0AAA9TI08-1", "sequence": { "sequence": "MEGLLSPMRTKMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKEEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSSSLQTSPIRSLPHWNSQCSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYVEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGVDEGDAGRLTPSRSQILRTPSLGREGVPDKGAGRAAVSDELRQWYQRSSASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYGDSCFLDSSLYPELADVQWYGQEKAKPGTLV", "length": 1037, "header": "tr|A0AAA9TI08-1|E1BHJ3_BOVIN Computationally mapped isoform of FERM domain containing 4A OS=Bos taurus OX=9913 GN=FRMD4A PE=4 SV=1 CANONICAL=E1BHJ3-1" }, "locus": { "chromosome": "13", "start_pos": 28870109, "end_pos": 28352495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087878.1", "url": "https://www.ensembl.org/id/ENSBTAT00000087878.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096550.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096550.1" } ] } }, { "isoform_ac": "E1BHJ3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3/entry#E1BHJ3-1", "sequence": { "sequence": "MAAGLLGSENLLNAWDRPVWGLTCRALRTCQGRNVRVLQLMLKPWCISRAVYQMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKEEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSSSLQTSPIRSLPHWNSQCSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYVEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGVDEGDAGRLTPSRSQILRTPSLGREGVPDKGAGRAAVSDELRQWYQRSSASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYGDSCFLDSSLYPELADVQWYGQEKAKPGTLV", "length": 1079, "header": "tr|E1BHJ3-1|E1BHJ3_BOVIN Isoform 1 of FERM domain containing 4A OS=Bos taurus OX=9913 GN=FRMD4A PE=4 SV=2 CANONICAL=E1BHJ3-1" }, "locus": { "chromosome": "13", "start_pos": 28679615, "end_pos": 28352495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010894.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010894.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010894.5", "url": "https://www.ensembl.org/id/ENSBTAP00000010894.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1032, "start_aa": "Thr", "end_pos": 1032, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1032", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:510714", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510714", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AR03-1", "protein_name": "FERM domain containing 4A", "gene_name": "Frmd4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGLLGSEDVPCSWDLACRVLRTCREGNLHLLQLMLKPWCIPRAVYQMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLFFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYCEDRVIEYYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKRLCLREAELTGKLPVEYPLDPGEEPPTVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLVIDDGNIASEDSSLSDALVLEDEDSQVTSTISPLQSPHKGLPPRPPSTHNRPPPPQSLEGLRQMHYHRTDYDKSPLKPKMWSESSLDEPYEKVKKRSSHGHSSSHKRFPSTGSCTEAGVSSSLQNSPIRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARSGAASAGGGVYLHSQSQPSSQYRIKEYPLYIEGSATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGSGRAAVSDELRLWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYGDSCFLDSSLYPELADVQWYGQEKAKPGTLV", "length": 1079 }, "evidence": [ { "id": "E1BHJ3", "url": "https://omabrowser.org/oma/group/E1BHJ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3AJF7-1", "protein_name": "FERM domain-containing protein 4A isoform X1", "gene_name": "frmd4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAVLLSLGESVCVRHSALWDVTSAALRRLRHAHFRAPEVLVRAVYQMTEGRRCQVHLLDDRKLELLVQPKLMAKDLLDLVASHFNLKEKEYFGISYVDETGHFSWLQLDRRVLEHEFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIEVDSEVVFELASYILQEAKGDFTSNDVTRADLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLSGQSRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYQDKVKPRKVFQWRQLENLYFREKKFSVEVHDPRSRASVTRRTFGHSGIAVHTWYACPTLIKSIWAMAISQHQFYLDRKQSKSKIHAARSLNEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQTAKKDMLAALRARQEALEETLRQRIEELKNICIREAELTGKLPKEYPLDPGEEPPTVRRKIGTAFKLDEQKILPKGEEEELERLEREFAIQSQITEAARRLASDPHISSKKLKKQRKTSYLNALKKLQDIENGINEYRVRSGKKPTQRASLIIEEANIGSEDSSLSDALVLDDDDSQVTGTPTFSPAASPHKGLPPRPPSHSRPPPPQSLDGLRHLHYQRSDYDKSPIKPRMWSESSLDEPYERVKKRSSHSSSHRRFPSTGSCEAGVSNSLQNSPVRSLPHWNSQSSMPSTPDLRTRSYVHSASLTQPFRGRSSSLESQGKLLSLEPDTEAGLSPDLFLSGPQRTGSNGSVVPDDCSSCTSHSSSEHYYPSSTSNPNYCTLAEDSPSKARQRQRQRHKSAGHLGASSSGSMPNLAARNGSTHGGVCGSHQGVYLHSQSQPSSQYRIKEYPLYTEGSSPNAVVVRSLENDQEGHYSVKAQFKTSNSYTAGGLYKEGWGSGEDGEAGGGGGSGRLTPSRSQIVRTPSLGREGGGGGGRAAVSEELRCWYQRSSGSIKEHSRVTHTSSNSSDGRGGRIGTLVKGSPAASPHSQRSGTPCSDPAATPPCSPQHILNWQSGSPFADITFLSSPLCSELADVQWYGHEKAKPGTLV", "length": 1065 }, "evidence": [ { "id": "E1BHJ3", "url": "https://omabrowser.org/oma/group/E1BHJ3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0XNA1-1", "protein_name": "FERM domain containing 4A", "gene_name": "FRMD4A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAGPSRVHLLHMTQRQLLLAALLPPSSSFLPLLLLLLPPLPLQPHSAVAVVQEPGAGGWQAGKGRGKRSAASRSGAWGEAVAHRPVPREAGDPVEGSGEERKGRGAAEEMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLHFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIEVDSEVVFELAAYILQEAKGDFSSNEVVRNELKKLPALPTPALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPREYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINEYRIKSGKKPTQRASLIIDEGNIASEDSSLSDALVLEDEDSQVTSTISPLQSPHKGLPPRPPLHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSNHKRFPSTGSCAEAGGSSSLQNSPIRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLAQHFRHRSSSLESQGKLLGSENETGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNPNYSTLAEDSPSKARERQRQRHKSAGNLVSSNSGSMPNLAARNGTGHHRVYLHSQSQPSSQYRIKEYPLYIEGSSTPVVVRSLENDQEGHYSVKAQFKTSNSYTAGGMFKENWHGDEADSVRLTPSRSQIIRTPSLGREGHEKGSGRTAVSDELRLWYQRSTASHKEHSRLSHTSSTSSDSSSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPHSQRSSTPSSELAATPPGSPHHILAWQTGTYNDSCFLDSPLYPELADVQWYGQEKAKPGTLV", "length": 1135 }, "evidence": [ { "id": "E1BHJ3", "url": "https://omabrowser.org/oma/group/E1BHJ3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RTX2-1", "protein_name": "FERM domain containing 4A", "gene_name": "FRMD4A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPKPWCISRAVYQMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRVKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSGSLQNSPVRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGAGRAAVSDELRQWYQRSSASHREHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYGDSCFLDSALYPELADVQWYGQEKAKPGTLV", "length": 1037 }, "evidence": [ { "id": "E1BHJ3", "url": "https://omabrowser.org/oma/group/E1BHJ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BIE6-1", "protein_name": "FERM domain-containing protein 4A", "gene_name": "Frmd4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYCEDRVIEYYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKRLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLVIDDGNIASEDSSLSDALVLEDEDSQVTSTISPLQSPHKGLPPRPPSSHNRPPPPQSLEGLRQLHYHRTDYDKSPLKPKMWSESSLDEPYEKVKKRSSHGHSSSHKRFPSTGSCTEAGVSSSLQNSPIRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARSGAASTGGGVYLHSQSQPSSQYRIKEYPLYIEGSATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGSGRAAVSDELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGEATENSPIMDGSESPTHQSTDE", "length": 1020 }, "evidence": [ { "id": "E1BHJ3", "url": "https://omabrowser.org/oma/group/E1BHJ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2Q2-1", "protein_name": "FERM domain-containing protein 4A", "gene_name": "FRMD4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVQLVPDSALGLLMMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTISPLHSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSNSLQNSPIRGLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARGGAGGAGGAGGGVYLHSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGGDEGDTGRLTPSRSQILRTPSLGREGAHDKGAGRAAVSDELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGEATENSPILDGSESPPHQSTDE", "length": 1039 }, "evidence": [ { "id": "E1BHJ3", "url": "https://omabrowser.org/oma/group/E1BHJ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E1BHJ3", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "E1BHJ3", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "E1BHJ3", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BHJ3", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "establishment of epithelial cell polarity", "id": "GO:0090162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090162", "evidence": [ { "database": "UniProtKB", "id": "E1BHJ3", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3" } ], "pmid": "" }, { "name": "negative regulation of protein secretion", "id": "GO:0050709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050709", "evidence": [ { "database": "UniProtKB", "id": "E1BHJ3", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3" } ], "pmid": "" }, { "name": "positive regulation of protein secretion", "id": "GO:0050714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050714", "evidence": [ { "database": "UniProtKB", "id": "E1BHJ3", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BHJ3", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 525, "end_pos": 527, "annotation": "n_glycosylation_sequon" }, { "start_pos": 761, "end_pos": 763, "annotation": "n_glycosylation_sequon" }, { "start_pos": 777, "end_pos": 779, "annotation": "n_glycosylation_sequon" }, { "start_pos": 805, "end_pos": 807, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHJ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1079, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHJ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHJ3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHJ3" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 360, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1032 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 525, "end_pos": 527 }, { "start_pos": 761, "end_pos": 763 }, { "start_pos": 777, "end_pos": 779 }, { "start_pos": 805, "end_pos": 807 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJI4-1", "uniprot_ac": "E1BJI4", "uniprot_id": "E1BJI4_BOVIN", "mass": { "chemical_mass": 121365.0, "monoisotopic_mass": 121365.0 }, "refseq": { "ac": "NP_001192674", "name": "ankyrin repeat- and BTB/POZ domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192674" }, "gene_names": [ { "name": "ABTB3", "type": "recommended", "evidence": [ { "id": "E1BJI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJI4" } ] }, { "name": "BTBD11", "type": "recommended", "evidence": [ { "id": "E1BJI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJI4" } ] }, { "name": "BTBD11", "type": "synonym", "evidence": [ { "id": "NP_001192674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192674" }, { "id": "E1BJI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJI4" } ] } ], "protein_names": [ { "name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "E1BJI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJI4/entry#names_and_taxonomy" } ] }, { "name": "BTB/POZ domain-containing protein 11", "type": "synonym", "evidence": [ { "id": "E1BJI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJI4/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat- and BTB/POZ domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "NP_001192674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192674" } ] } ], "function": [ { "annotation": "Cortical and hippocampal inhibitory interneuron-specific protein localized at glutamatergic (excitatory) synapses, where it supports cell type-specific synaptic function.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SAS2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAS2#function" }, { "database": "UniProtKB", "id": "ARBA00094471", "url": "https://www.uniprot.org/uniprotkb/ARBA00094471#function" }, { "database": "UniProtKB", "id": "E1BJI4", "url": "https://www.uniprot.org/uniprotkb/E1BJI4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJI4", "url": "https://www.uniprot.org/uniprotkb/E1BJI4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ABTB3", "url": "https://www.uniprot.org/uniprotkb/E1BJI4", "locus": { "chromosome": "5", "start_pos": 70908786, "end_pos": 70577473, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000027064", "url": "https://www.ensembl.org/id/ENSBTAG00000027064" } ] } } ], "crossref": [ { "id": "E1BJI4", "url": "https://alphafold.ebi.ac.uk/entry/E1BJI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000027064", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000027064", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18351", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18351", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18527", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18527", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539986", "url": "https://www.ncbi.nlm.nih.gov/gene/539986", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "E1BJI4", "url": "https://www.ebi.ac.uk/intact/interactors/id:E1BJI4*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539986", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539986", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NLHREPQ", "url": "https://omabrowser.org/oma/group/NLHREPQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJI4", "url": "https://www.orthodb.org/?gene=E1BJI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46071:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46071:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192674", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192674", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SAS2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAS2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY23-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJI4", "url": "https://www.uniprot.org/uniprotkb/E1BJI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJI4-1", "url": "https://www.uniprot.org/uniprotkb/E1BJI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLTDSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELEALLLRSRDPRAGPVAPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYARVVASGLPRSCSGLGPGSSSGPGQGSGPGAAPAADKEREVPGGGAASGGACSAASSASGGSSCCAPPTVAAAAAAAAAPPAAAANHHHHHHHALHEAPKFTVETLEYTVNNDSEIWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRTSKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPLHHKQGALYWEPEALYTLCYFMHCPQMEWENPNVEPSKVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLRADDCFCASRKLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDGINTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSTPHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTTPQGDMNSFSQAAAHGHRNVFRKLLAQPEKEKSDILSLEEILAEGTDLAETAPPPLCASRNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDSTCIEIGYVKYPIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSINTDNCVDIYNHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGTGQDVLQDLQRTLAIRIQSIHLSSSKGSVV", "length": 1108, "header": "tr|E1BJI4-1|E1BJI4_BOVIN Isoform 1 of Ankyrin repeat- and BTB/POZ domain-containing protein 3 OS=Bos taurus OX=9913 GN=ABTB3 PE=4 SV=1 CANONICAL=E1BJI4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SAS2-1", "url": "https://www.uniprot.org/uniprotkb/E1BJI4/entry#A0AAA9SAS2-1", "sequence": { "sequence": "MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLTDSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELEALLLRSRDPRAGPVAPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYARVVASGLPRSCSGLGPGSSSGPGQGSGPGAAPAADKEREVPGGGAASGGACSAASSASGGSSCCAPPTVAAAAAAAAAPPAAAANHHHHHHHALHEAPKFTVETLEYTVNNDSEIWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRTSKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPLHHKQGALYWEPEALYTLCYFMHCPQMEWENPNVEPSKVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLRADDCFCASRKLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDGINTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSTPHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDSTCIEIGYVKYPIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSINTDNCVDIYNHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGTGQDVLQDLQRTLAIRIQSIHLSSSKGSVV", "length": 989, "header": "tr|A0AAA9SAS2-1|E1BJI4_BOVIN Computationally mapped isoform of Ankyrin repeat- and BTB/POZ domain-containing protein 3 OS=Bos taurus OX=9913 GN=ABTB3 PE=4 SV=1 CANONICAL=E1BJI4-1" }, "locus": { "chromosome": "5", "start_pos": 70907835, "end_pos": 70577672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103652.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103652.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081006.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081006.1" } ] } }, { "isoform_ac": "A0AAA9SY23-1", "url": "https://www.uniprot.org/uniprotkb/E1BJI4/entry#A0AAA9SY23-1", "sequence": { "sequence": "MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLTDSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELEALLLRSRDPRAGPVAPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYARVVASGLPRSCSGLGPGSSSGPGQGSGPGAAPAADKEREVPGGGAASGGACSAASSASGGSSCCAPPTVAAAAAAAAAPPAAAANHHHHHHHALHEAPKFTVETLEYTVNNDSEIWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRTSKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPLHHKQGALYWEPEALYTLCYFMHCPQMEWENPNVEPSKVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLRADDCFCASRKLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDGINTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSTPHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTTPQGDMNSFSQAAAHGHRNVFRKLLAQPEKEKSDILSLEEILAEGTDLAETAPPPLCASRNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDSTCIEIGYVKYPIFQLLSAAKFFQLEALQRHCEIICAKSINTDNCVDIYNHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGTGQDVLQDLQRTLAIRIQSIHLSSSKGSVV", "length": 1085, "header": "tr|A0AAA9SY23-1|E1BJI4_BOVIN Computationally mapped isoform of Ankyrin repeat- and BTB/POZ domain-containing protein 3 OS=Bos taurus OX=9913 GN=ABTB3 PE=4 SV=1 CANONICAL=E1BJI4-1" }, "locus": { "chromosome": "5", "start_pos": 70907835, "end_pos": 70577672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109813.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109813.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088217.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088217.1" } ] } }, { "isoform_ac": "E1BJI4-1", "url": "https://www.uniprot.org/uniprotkb/E1BJI4/entry#E1BJI4-1", "sequence": { "sequence": "MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLTDSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELEALLLRSRDPRAGPVAPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYARVVASGLPRSCSGLGPGSSSGPGQGSGPGAAPAADKEREVPGGGAASGGACSAASSASGGSSCCAPPTVAAAAAAAAAPPAAAANHHHHHHHALHEAPKFTVETLEYTVNNDSEIWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRTSKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPLHHKQGALYWEPEALYTLCYFMHCPQMEWENPNVEPSKVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLRADDCFCASRKLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDGINTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSTPHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTTPQGDMNSFSQAAAHGHRNVFRKLLAQPEKEKSDILSLEEILAEGTDLAETAPPPLCASRNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDSTCIEIGYVKYPIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSINTDNCVDIYNHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGTGQDVLQDLQRTLAIRIQSIHLSSSKGSVV", "length": 1108, "header": "tr|E1BJI4-1|E1BJI4_BOVIN Isoform 1 of Ankyrin repeat- and BTB/POZ domain-containing protein 3 OS=Bos taurus OX=9913 GN=ABTB3 PE=4 SV=1 CANONICAL=E1BJI4-1" }, "locus": { "chromosome": "5", "start_pos": 70907835, "end_pos": 70577672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061102.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061102.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053857.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053857.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539986", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539986", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6QL63-1", "protein_name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3", "gene_name": "ABTB3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELEALLLRSRDPRAGPAVPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVVASGVPRSCSGPGSGSGSGPGPSSGPGAAPAADKEREAPGGGAASGGACSAASSASGGSSCCAPPAAAAAAVPPAAAANHHHHHHHALHEAPKFTVETLEHTVNNDSEIWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRSNKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPLHHKQGALYWEPEALYTLCYFMHCPQMEWENPNVEPSKVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLRADDCFCASRKLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDGINTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSTPHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTTPQGDMNSFSQAAAHGHRNVFRKLLAQPEKEKSDILSLEEILAEGTDLAETAPPPLCASRNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDGTCIEIGYVKYSIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSINTDNCVDIYNHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGTGQDVLQDLQRTLAIRIQSIHLSSSKGSVV", "length": 1104 }, "evidence": [ { "id": "E1BJI4", "url": "https://omabrowser.org/oma/group/E1BJI4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4AC89-1", "protein_name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3", "gene_name": "Abtb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELELLLLRSRDPRAGPAAPGSLPKDALAKLSMLVSRALVRIAKEAQRLSLRFAKCTKYEVQSAMEIVLSWGLAARCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYTRVLASGLPRSCSGPGPGSSSSSGPGPGSGPGAPTADKERETPGGGAASGGPCSAASSASGGSSCCAPPATAATAVPPATATAAAPTAANHHHHHHHHTLHEAPKFTVETLEHTVNNDSEIWGLLQPYQHLICGKNASGVLSLPESLNLHRDPQRPSKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNVKHHGNGTPLHHKQGALYWEPEALYTLCYFMHCPQMEWENPNVEPSKVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLKADDCFCASRKLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDGINTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSSPHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTTPQGDMNSFSQAAAHGHRNVFRKLLAQPEKEKSDILSLEEILAEGTDLAETAPPPLCASRNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDSTCVEIGYVKYPIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSVNTDNCVDIYSHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGTGQDVLQDLQRTLAIRIQSIHLSSSKGSVV", "length": 1113 }, "evidence": [ { "id": "E1BJI4", "url": "https://omabrowser.org/oma/group/E1BJI4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SPR7-1", "protein_name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3", "gene_name": "ABTB3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELEALLLRSRDPRAGPVAPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYARVVASGLPRSCSGPGPGSSSGPGPGSGPGAAPAADKERETPGGGAASGGACSAASSASGGSSCCAPPAAAASAASAAPPVAASANHHHHHHHALHEAPKFTVETLEHTVNNDSEIWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRTSKPGELAMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPLHHKQGALYWEPEALYTLCYFMHCPQMEWENPNVEPSKVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLRADDCFCASRKLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDGINTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSTPHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTTPQGDMNSFSQAAAHGHRNVFRKLLAQPEKEKSDILSLEEILAEGTDLAETAPPPLCASRNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELITQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDSTCIEIGYVKYPIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSINTDNCVDIYNHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGTGQDVLQDLQRTLAIRIQSIHLSSSKGSVV", "length": 1108 }, "evidence": [ { "id": "E1BJI4", "url": "https://omabrowser.org/oma/group/E1BJI4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1LVW0-1", "protein_name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3-A", "gene_name": "abtb3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGKGKTAARTLEDLTLDSGYGGAADSFRSSSVSLCCSDTHLSYAHGGNCWHLTESMHSRHNSLDTVNTVLAEDTEILECSGQCAKLPELEEDVPWSLGEVEGALRKDEELCVGNASREILAKLSALVSRALVRIAREAQRMSLRYARCTKHEIQSAIKMVLSWTISVNCITAALSALSLYNMSTGDKFSRGKSTRCGLIFSVGKFFRWMVDSRVALRIHEHAAIYLSACMESLFREVFTRVQRSALVEKENGVPKFSVESLEQAINNDSELWGLLQPYQHLICGKNASGVLSLPDSLNLHRDQQRAGKTGEGHAYSQAELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLHIKNPSNGTPVHQNRTGSVHWEPEALYTLCYFMHCPQMEWENPNVEPSKITLHTERPFLVLPPLMEWIRVAVAHTEHRRSFSVDSDDVRQAARLLLPGVDCEPRQLKADDCFCATRKLDAASTEAKFLQDLGFRMLNCGRTDLVKQAVNLLGPDGINSMSEQGMTPLMYSCVRGDEAMVQMLLDAGADINSEVPSSLHKHPSVYPDTRQGTPLTFAVLHGHVPVVQLLLDARANVEGAIQESTENYTETPLQLASAAGNFELVSLLLERGADPLIGTTYRNGISSGPLGEMNSYSLAAAHGHRNVFRKLLSQVEKDKGDVLSLEEMLAEGSEAVERRAPQNEGTLRTGKAKLRALREAMYHSAEHGHVDITIDIRSLGVPWTLHTWLESLRTCFVQQRRPLIQGLLKDFSCIKEDEYTEELITHGLPLMFQILRASKNEVISQQLSVIFTQCYGPFPIPKLTEIKKKQTSRLDPHFLNNKEMSDVTFLVEGKPFYAHKVLLFTASPRFKSLLSNRPAAENTCIEISHVKYNIFQLVMQYLYCGGTESLHIRNTEIMELLSAAKFFQLDALQRHCEIICSKNITNDSCVDIYKHARFLGALELAGFIEGFFLKNMVLLIELENFKQLLYEVPADSPGPGPSYDVLHDLEQTLALRIRSIHLSTSKGSIV", "length": 1021 }, "evidence": [ { "id": "E1BJI4", "url": "https://omabrowser.org/oma/group/E1BJI4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6GQW0-1", "protein_name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3", "gene_name": "Abtb3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELELLLLRSRDPRAGPAVPGSLPKDALAKLSMLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVLASGLPRSCSGPGPGSSSGSGPGPGSGPGAPAADKERETPGGGAASGGPCSAASSASGGSSCCAPPATAATAVPPTTATAAVAANHHHHHHTLHEAPKFTVETLEHTVNNDSEIWGLLQPYQHLICGKNASGVLSLPESLNLHRDPQRPSKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPMHHKQGALYWEPEALYTLCYFMHCPQMEWENPNVEPSKVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLKADDCFCASRKLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDGINTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSTPHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTTPQGDMNSFSQAAAHGHRNVFRKLLAQPEKEKSDILSLEEILAEGTDLAETAPPPLCASRNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDNTCIEIGYVKYPIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSINTDNCVDIYSHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGAGQDVLQDLQRTLAIRIQSIHLSSSKGSVV", "length": 1109 }, "evidence": [ { "id": "E1BJI4", "url": "https://omabrowser.org/oma/group/E1BJI4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BJI4", "url": "https://www.uniprot.org/uniprotkb/E1BJI4" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BJI4", "url": "https://www.uniprot.org/uniprotkb/E1BJI4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BJI4", "url": "https://www.uniprot.org/uniprotkb/E1BJI4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "E1BJI4", "url": "https://www.uniprot.org/uniprotkb/E1BJI4" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "E1BJI4", "url": "https://www.uniprot.org/uniprotkb/E1BJI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 962, "end_pos": 964, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJI4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1108, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJI4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJI4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJI4" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 927, "end_pos": 987, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 33, "end_pos": 35 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 690, "end_pos": 692 }, { "start_pos": 962, "end_pos": 964 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFY8-1", "uniprot_ac": "E1BFY8", "uniprot_id": "E1BFY8_BOVIN", "mass": { "chemical_mass": 61778.0, "monoisotopic_mass": 61778.0 }, "refseq": { "ac": "XP_024852016", "name": "leucine-rich repeat LGI family member 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852016" }, "gene_names": [ { "name": "LGI3", "type": "recommended", "evidence": [ { "id": "E1BFY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFY8" } ] }, { "name": "LGI3", "type": "synonym", "evidence": [ { "id": "XP_024852016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852016" } ] } ], "protein_names": [ { "name": "Leucine rich repeat LGI family member 3", "type": "synonym", "evidence": [ { "id": "E1BFY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFY8/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat LGI family member 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_024852016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852016" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFY8", "url": "https://www.uniprot.org/uniprotkb/E1BFY8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LGI3", "url": "https://www.uniprot.org/uniprotkb/E1BFY8", "locus": { "chromosome": "8", "start_pos": 69461492, "end_pos": 69468646, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004578", "url": "https://www.ensembl.org/id/ENSBTAG00000004578" } ] } } ], "crossref": [ { "id": "E1BFY8", "url": "https://alphafold.ebi.ac.uk/entry/E1BFY8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004578", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004578", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "516661", "url": "https://www.ncbi.nlm.nih.gov/gene/516661", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051295", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051295", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WDTNIDK", "url": "https://omabrowser.org/oma/group/WDTNIDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24367", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24367", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24367:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24367:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5682910", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5682910", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024852016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852016", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SC44", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SC44-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFY8", "url": "https://www.uniprot.org/uniprotkb/E1BFY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFY8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGLQARRVSGLRLLALSTLGLCLMLQVGAKRPPKTPPCPPSCSCTRDTAFCVDSKAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILSDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLSFPAVSAEPFLYSSDLYLALAQPGASACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDSQLYVVVAQLFGGSYIYHWDPNTTRFTKLQDIDPQRVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHPWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGARFSEVQALPSRGSLALQPFLVGGRRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHVVVDLSA", "length": 548, "header": "tr|E1BFY8-1|E1BFY8_BOVIN Isoform 1 of Leucine rich repeat LGI family member 3 OS=Bos taurus OX=9913 GN=LGI3 PE=4 SV=3 CANONICAL=E1BFY8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SC44-1", "url": "https://www.uniprot.org/uniprotkb/E1BFY8/entry#A0AAA9SC44-1", "sequence": { "sequence": "MAGLQARRVSGLRLLALSTLGLCLMLQVGAKRPPKTPPCPPSCSCTRDTAFCVDSKAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLSLANNNLQTLPRDIFRPLDILSDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLSFPAVSAEPFLYSSDLYLALAQPGASACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDSQLYVVVAQLFGGSYIYHWDPNTTRFTKLQDIDPQRVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHPWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGARFSEVQALPSRGSLALQPFLVGGRRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHVVVDLSA", "length": 524, "header": "tr|A0AAA9SC44-1|E1BFY8_BOVIN Computationally mapped isoform of Leucine rich repeat LGI family member 3 OS=Bos taurus OX=9913 GN=LGI3 PE=4 SV=1 CANONICAL=E1BFY8-1" }, "locus": { "chromosome": "8", "start_pos": 69468447, "end_pos": 69462496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091069.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091069.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083681.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083681.1" } ] } }, { "isoform_ac": "E1BFY8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFY8/entry#E1BFY8-1", "sequence": { "sequence": "MAGLQARRVSGLRLLALSTLGLCLMLQVGAKRPPKTPPCPPSCSCTRDTAFCVDSKAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILSDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLSFPAVSAEPFLYSSDLYLALAQPGASACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDSQLYVVVAQLFGGSYIYHWDPNTTRFTKLQDIDPQRVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHPWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGARFSEVQALPSRGSLALQPFLVGGRRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHVVVDLSA", "length": 548, "header": "tr|E1BFY8-1|E1BFY8_BOVIN Isoform 1 of Leucine rich repeat LGI family member 3 OS=Bos taurus OX=9913 GN=LGI3 PE=4 SV=3 CANONICAL=E1BFY8-1" }, "locus": { "chromosome": "8", "start_pos": 69468447, "end_pos": 69462496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006011.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006011.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006011.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006011.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5682910", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5682910", "resource": "Reactome", "description": "LGI-ADAM interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BHH5-1", "protein_name": "Leucine rich repeat LGI family member 3", "gene_name": "LGI3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRPGPQALLSVATPRPGLPLRPARPRRPPPPPPQSASSPAGQPWARPGLRASLPASGSQERAGEGTAAQGPRSLSRLRAAGALAAAAAAGGREVPVPARAVAQSRWLELTGSMAGPRARRGSGLGLLALSTLGLCLMLQVGAKRPPKTPPCPPSCSCTRDTAFCVDSKAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILSDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLSFPAVSAEPFLYSSDLYLALAQPGASACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDSQLYVVVAQLFGGSYIYHWDPNTTRFTKLQDIDPQRVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHAWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGRRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHVVVDLSA", "length": 661 }, "evidence": [ { "id": "E1BFY8", "url": "https://omabrowser.org/oma/group/E1BFY8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MMA1-1", "protein_name": "Leucine-rich repeat LGI family member 3", "gene_name": "Lgi3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGLGARLGPGRRLLVLSTLGFCLMLQASAKRPPKTPPCPPSCSCTRDTAFCVDSKAVPKNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFVENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILSDLDLRGNALNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLSFPAVSAEPFLYSSDLYLALAQPGASACTVLKWDYVERQLRDYDRIPAPSAVHCKPMVVDGQLYVVVAQLFGGSYIYHWDPNTTRFTKLQDIDPQRVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHAWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRSQKQFVVQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGHRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHVVVDLSA", "length": 548 }, "evidence": [ { "id": "E1BFY8", "url": "https://omabrowser.org/oma/group/E1BFY8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZN61-1", "protein_name": "Leucine-rich repeat LGI family, member 3", "gene_name": "Lgi3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLRARRGPMCRLLVLSTLGFYLMLQASAKRPPKTPPCPPSCSCTRDTAFCVDSKSVPKNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWGLSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILSDLDLRGNALNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLSFPAVSAEPFLYSSDLYLALAQPGASACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDGQLYVVVAQLFGGSYIYHWDPNTTRFTKLQDIDPQRVRKPNDLEAFRIDGDWFFAVADSSKAGATSLYRWHQNGFYSHQALHAWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGHRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHVVVDLSA", "length": 548 }, "evidence": [ { "id": "E1BFY8", "url": "https://omabrowser.org/oma/group/E1BFY8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K406-1", "protein_name": "Leucine-rich repeat LGI family member 3", "gene_name": "Lgi3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGLRARRGPGRRLLVLSTLGFCLMLQVSAKRPPKTPPCPPSCSCTRDTAFCVDSKSVPKNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFIGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILSDLDLRGNALNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLSFPAVSAEPFLYSSDLYLALAQPGASACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDGQLYVVVAQLFGGSYIYHWDPNTTRFTKLQDIDPQRVRKPNDLEAFRIDGDWFFAVADSSKAGATSLYRWHQNGFYSHQALHAWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRSQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGHRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHVVVDLSA", "length": 548 }, "evidence": [ { "id": "E1BFY8", "url": "https://omabrowser.org/oma/group/E1BFY8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N145-1", "protein_name": "Leucine-rich repeat LGI family member 3", "gene_name": "LGI3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGLRARGGPGPGLLALSALGFCLMLQVSAKRPPKTPPCPPSCSCTRDTAFCVDSKAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLAFPAVSAEPFLYSSDLYLALAQPGVSACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDSQLYVVVAQLFGGSYIYHWDPNTTRFTRLQDIDPQRVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHPWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGRRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHIVVDLSA", "length": 548 }, "evidence": [ { "id": "E1BFY8", "url": "https://omabrowser.org/oma/group/E1BFY8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BFY8", "url": "https://www.uniprot.org/uniprotkb/E1BFY8" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BFY8", "url": "https://www.uniprot.org/uniprotkb/E1BFY8" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "E1BFY8", "url": "https://www.uniprot.org/uniprotkb/E1BFY8" } ], "pmid": "" }, { "name": "juxtaparanode region of axon", "id": "GO:0044224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044224", "evidence": [ { "database": "UniProtKB", "id": "E1BFY8", "url": "https://www.uniprot.org/uniprotkb/E1BFY8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of exocytosis", "id": "GO:0017157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017157", "evidence": [ { "database": "UniProtKB", "id": "E1BFY8", "url": "https://www.uniprot.org/uniprotkb/E1BFY8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFY8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 548, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFY8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFY8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFY8" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 219, "start_aa": "Asn", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 311, "end_pos": 313 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEI0-1", "uniprot_ac": "E1BEI0", "uniprot_id": "E1BEI0_BOVIN", "mass": { "chemical_mass": 59007.0, "monoisotopic_mass": 59007.0 }, "refseq": { "ac": "XP_024831206", "name": "apoptosis inhibitor 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831206" }, "gene_names": [ { "name": "API5", "type": "recommended", "evidence": [ { "id": "E1BEI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI0" } ] }, { "name": "API5", "type": "synonym", "evidence": [ { "id": "XP_024831206", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831206" } ] } ], "protein_names": [ { "name": "Apoptosis inhibitor 5", "type": "recommended", "evidence": [ { "id": "E1BEI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI0/entry#names_and_taxonomy" } ] }, { "name": "apoptosis inhibitor 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024831206", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831206" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEI0", "url": "https://www.uniprot.org/uniprotkb/E1BEI0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "API5", "url": "https://www.uniprot.org/uniprotkb/E1BEI0", "locus": { "chromosome": "15", "start_pos": 73450983, "end_pos": 73423823, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014474", "url": "https://www.ensembl.org/id/ENSBTAG00000014474" } ] } } ], "crossref": [ { "id": "E1BEI0", "url": "https://alphafold.ebi.ac.uk/entry/E1BEI0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014474", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014474", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538968", "url": "https://www.ncbi.nlm.nih.gov/gene/538968", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BEI0", "url": "https://www.orthodb.org/?gene=E1BEI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12758", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12758", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12758:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12758:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05918", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05918", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024831206", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831206", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SCS1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCS1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDF2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDF2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIJ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5R4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5R4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEI0", "url": "https://www.uniprot.org/uniprotkb/E1BEI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEI0-1", "url": "https://www.uniprot.org/uniprotkb/E1BEI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSSLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTDENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVELGQKRATEDTTSGSPPKKSSAGPKRDARQIYNPPSGKYSSNLSNFNYEQRGAFRGSRGGRGWGARGNRSRGRVY", "length": 524, "header": "tr|E1BEI0-1|E1BEI0_BOVIN Isoform 1 of Apoptosis inhibitor 5 OS=Bos taurus OX=9913 GN=API5 PE=3 SV=4 CANONICAL=E1BEI0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SCS1-1", "url": "https://www.uniprot.org/uniprotkb/E1BEI0/entry#A0AAA9SCS1-1", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSSLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTDENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVELGQKRATEDTTSGSPPKKSSAGPKRDARQIYNPPSGKYSSNLSNFNYERSLQGK", "length": 450, "header": "tr|A0AAA9SCS1-1|E1BEI0_BOVIN Computationally mapped isoform of Apoptosis inhibitor 5 OS=Bos taurus OX=9913 GN=API5 PE=3 SV=1 CANONICAL=E1BEI0-1" }, "locus": { "chromosome": "15", "start_pos": 73449920, "end_pos": 73423963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135014.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135014.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081657.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081657.1" } ] } }, { "isoform_ac": "A0AAA9SDF2-1", "url": "https://www.uniprot.org/uniprotkb/E1BEI0/entry#A0AAA9SDF2-1", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSSLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTDENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVELGQKRATEDTTSGSPPKKSSAGPKRDARQIYNPPSGKYSSNLSNFNYG", "length": 498, "header": "tr|A0AAA9SDF2-1|E1BEI0_BOVIN Computationally mapped isoform of Apoptosis inhibitor 5 OS=Bos taurus OX=9913 GN=API5 PE=3 SV=1 CANONICAL=E1BEI0-1" }, "locus": { "chromosome": "15", "start_pos": 73446534, "end_pos": 73423963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131489.2", "url": "https://www.ensembl.org/id/ENSBTAT00000131489.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081591.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081591.1" } ] } }, { "isoform_ac": "A0AAA9SIJ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BEI0/entry#A0AAA9SIJ8-1", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSSLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTDENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVELGQKRATEDTTSGSPPKKSSAGPKRDARQIYNPPSGKYSSNLSNFNYGVCSHNVVQLPGAFSIKVFAHTHV", "length": 521, "header": "tr|A0AAA9SIJ8-1|E1BEI0_BOVIN Computationally mapped isoform of Apoptosis inhibitor 5 OS=Bos taurus OX=9913 GN=API5 PE=3 SV=1 CANONICAL=E1BEI0-1" }, "locus": { "chromosome": "15", "start_pos": 73448527, "end_pos": 73423963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119671.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119671.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085148.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085148.1" } ] } }, { "isoform_ac": "A0AAA9T5R4-1", "url": "https://www.uniprot.org/uniprotkb/E1BEI0/entry#A0AAA9T5R4-1", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSSLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTDENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVELGEEPSGEVEVAEVGEHEEIVVGEESTE", "length": 478, "header": "tr|A0AAA9T5R4-1|E1BEI0_BOVIN Computationally mapped isoform of Apoptosis inhibitor 5 OS=Bos taurus OX=9913 GN=API5 PE=3 SV=1 CANONICAL=E1BEI0-1" }, "locus": { "chromosome": "15", "start_pos": 73449979, "end_pos": 73423963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092255.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092255.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092067.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092067.1" } ] } }, { "isoform_ac": "E1BEI0-1", "url": "https://www.uniprot.org/uniprotkb/E1BEI0/entry#E1BEI0-1", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSSLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTDENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVELGQKRATEDTTSGSPPKKSSAGPKRDARQIYNPPSGKYSSNLSNFNYEQRGAFRGSRGGRGWGARGNRSRGRVY", "length": 524, "header": "tr|E1BEI0-1|E1BEI0_BOVIN Isoform 1 of Apoptosis inhibitor 5 OS=Bos taurus OX=9913 GN=API5 PE=3 SV=4 CANONICAL=E1BEI0-1" }, "locus": { "chromosome": "15", "start_pos": 73449975, "end_pos": 73423963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030639.7", "url": "https://www.ensembl.org/id/ENSBTAT00000030639.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030612.6", "url": "https://www.ensembl.org/id/ENSBTAP00000030612.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BEI0", "url": "https://www.uniprot.org/uniprotkb/E1BEI0" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BEI0", "url": "https://www.uniprot.org/uniprotkb/E1BEI0" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "E1BEI0", "url": "https://www.uniprot.org/uniprotkb/E1BEI0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "E1BEI0", "url": "https://www.uniprot.org/uniprotkb/E1BEI0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1BEI0", "url": "https://www.uniprot.org/uniprotkb/E1BEI0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BEI0", "url": "https://www.uniprot.org/uniprotkb/E1BEI0" } ], "pmid": "" }, { "name": "fibroblast growth factor binding", "id": "GO:0017134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017134", "evidence": [ { "database": "UniProtKB", "id": "E1BEI0", "url": "https://www.uniprot.org/uniprotkb/E1BEI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEI0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 524, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEI0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEI0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 517, "end_pos": 519 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFK8-1", "uniprot_ac": "E1BFK8", "uniprot_id": "E1BFK8_BOVIN", "mass": { "chemical_mass": 102202.0, "monoisotopic_mass": 102202.0 }, "refseq": { "ac": "XP_003586511", "name": "DNA-binding protein RFX6 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586511" }, "gene_names": [ { "name": "RFX6", "type": "recommended", "evidence": [ { "id": "E1BFK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ] }, { "name": "RFX6", "type": "synonym", "evidence": [ { "id": "XP_003586511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586511" } ] } ], "protein_names": [ { "name": "DNA-binding protein RFX6", "type": "recommended", "evidence": [ { "id": "E1BFK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFK8/entry#names_and_taxonomy" } ] }, { "name": "DNA-binding protein RFX6 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003586511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586511" } ] }, { "name": "Regulatory factor X 6", "type": "synonym", "evidence": [ { "id": "E1BFK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFK8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin. Not required for pancreatic PP (polypeptide-producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by forming a heterodimer with RFX3 and binding to the X-box in the promoter of target genes. Involved in glucose-stimulated insulin secretion by promoting insulin and L-type calcium channel gene transcription.", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8#function" }, { "database": "UniProtKB", "id": "ARBA00056208", "url": "https://www.uniprot.org/uniprotkb/ARBA00056208#function" }, { "database": "UniProtKB", "id": "A0AAA9SDF6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDF6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RFX6", "url": "https://www.uniprot.org/uniprotkb/E1BFK8", "locus": { "chromosome": "9", "start_pos": 33719813, "end_pos": 33772545, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000264", "url": "https://www.ensembl.org/id/ENSBTAG00000000264" } ] } } ], "crossref": [ { "id": "E1BFK8", "url": "https://alphafold.ebi.ac.uk/entry/E1BFK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000264", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000264", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "524074", "url": "https://www.ncbi.nlm.nih.gov/gene/524074", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524074", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524074", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FAKNWEH", "url": "https://omabrowser.org/oma/group/FAKNWEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFK8", "url": "https://www.orthodb.org/?gene=E1BFK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25340", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25340", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003586511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586511", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SDF6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDF6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFK8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKLPELEDAFLQAQASPPVSPEVQECCVQLLGKGLLVYPEERVYLAAEAQPGRALGSGEKADDPELPGGVKSEMHLSNGNFSSEEEDADNPDSKTKATDPHLSQKKTITQIMKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCLSKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIEKVDLNSIGSQALLTISGSTDTESDIYTEYDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSTVPSDTVKNESHVETTYLPLSSSQPGGLTSALHLFPAGNTDNMPLPGQMELSQSSGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCSAYSEPIYPTFPQASHDFYGTNSNYQTVFRTQPHTPSGLYPHRPEHSRCMVWSDQQLSRDFFSGSCAGSPYNSRPPSSYGPSPHGQDPHSLQFLNTGGFNFLSNAGGASCQGATLPPNSPNGYYGGNVNYPESHRLGSMVNQHVSVISSVRSLPPYGDIHDPLNILDDGSRKQTSSFYADTPPSVACRTPVVASSLQTPIPSSSSQCMYGTSNQYPAQEPLDSHGANGREMVSSLPPINTVFMGTAAGGT", "length": 927, "header": "tr|E1BFK8-1|E1BFK8_BOVIN Isoform 1 of DNA-binding protein RFX6 OS=Bos taurus OX=9913 GN=RFX6 PE=4 SV=2 CANONICAL=E1BFK8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SDF6-1", "url": "https://www.uniprot.org/uniprotkb/E1BFK8/entry#A0AAA9SDF6-1", "sequence": { "sequence": "MAKLPELEDAFLQAQASPPVSPEVQECCVQLLGKGLLVYPEERVYLAAEAQPGRALGSGEKADDPELPGGVKSEMHLSNGNFSSEEEDADNPDSKTKATDPHLSQKKTITQIMKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCLSKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIEKVDLNSIGSQALLTISGSTDTESDIYTEYDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSTVPSDTVKNESHVETTYLPLSSSQPGGLTSALHLFPAGNTDNMPLPGQMELSQSSGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCSAYSEPIYPTFPQASHDFYGTNSNYQTVFRTQPHTPSGLYPHRPEHSRCMVWSDQQLSRDFFSGSCAGSPYNSRPPSSYGPSPHGQDPHSLQFLNTGGFNFLSNAGGASCQGATLPPNSPNASSLQTPIPSSSSQCMYGTSNQYPAQEPLDSHGANGREMVSSLPPINTVFMGTAAGGT", "length": 856, "header": "tr|A0AAA9SDF6-1|E1BFK8_BOVIN Computationally mapped isoform of DNA-binding protein RFX6 OS=Bos taurus OX=9913 GN=RFX6 PE=4 SV=1 CANONICAL=E1BFK8-1" }, "locus": { "chromosome": "9", "start_pos": 33772346, "end_pos": 33720569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088908.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088908.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083444.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083444.1" } ] } }, { "isoform_ac": "E1BFK8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFK8/entry#E1BFK8-1", "sequence": { "sequence": "MAKLPELEDAFLQAQASPPVSPEVQECCVQLLGKGLLVYPEERVYLAAEAQPGRALGSGEKADDPELPGGVKSEMHLSNGNFSSEEEDADNPDSKTKATDPHLSQKKTITQIMKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCLSKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIEKVDLNSIGSQALLTISGSTDTESDIYTEYDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSTVPSDTVKNESHVETTYLPLSSSQPGGLTSALHLFPAGNTDNMPLPGQMELSQSSGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCSAYSEPIYPTFPQASHDFYGTNSNYQTVFRTQPHTPSGLYPHRPEHSRCMVWSDQQLSRDFFSGSCAGSPYNSRPPSSYGPSPHGQDPHSLQFLNTGGFNFLSNAGGASCQGATLPPNSPNGYYGGNVNYPESHRLGSMVNQHVSVISSVRSLPPYGDIHDPLNILDDGSRKQTSSFYADTPPSVACRTPVVASSLQTPIPSSSSQCMYGTSNQYPAQEPLDSHGANGREMVSSLPPINTVFMGTAAGGT", "length": 927, "header": "tr|E1BFK8-1|E1BFK8_BOVIN Isoform 1 of DNA-binding protein RFX6 OS=Bos taurus OX=9913 GN=RFX6 PE=4 SV=2 CANONICAL=E1BFK8-1" }, "locus": { "chromosome": "9", "start_pos": 33772346, "end_pos": 33720569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000329.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000329.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000329.5", "url": "https://www.ensembl.org/id/ENSBTAP00000000329.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:524074", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524074", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AS29-1", "protein_name": "DNA-binding protein RFX6", "gene_name": "Rfx6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKVRELEETFVHEQPSPQLPSEIAEECGAQLLGKGLLVYSEESAYLVASARSSEEKDGDLGLQVGVKSEMHLNNGNFSSEEDDADTQESKTKATDPQLSQKKSITQIMKDKKKQTQLTLQWLEDNYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYPGCIAKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALIDKKIPILRRFVSSLKRQTSFLHLAQIARPALFDQHVVNAMVSDIEKVDLNSIGSQALLTISNSTDTESDIYSEYDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKMSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSLHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSEASKAAFTASPSSCFLANRNKGSSLSSDPVKNESHEETAYVPLPSSQPLAVPHALHSFPAESTETMPLSGQIELSQSTGHLMTPPISPAIASRGSVINQGPMAGRPSSVGTALSAPTHCPTYAEPIYPTLPPANHDFYGTNSNYQTVFRAQSHPASSLYAHRAENGRCMAWTEQQLSRDFFGGSCAGSPYNSRPPSGYGPSPATQESHNMQFLNTGSFNFLSNAGTGSCQGAALPSNSPNGYYGNNINYPEAHRLGSMVNQHVSVISSVRSLPPYSDIHDPLNILDDSGRKQSNLFYAHTSSPVTCRTPVVASNLQTQIPPSSSQCMYGTSGQYPVQDNLDSNGASDREMVSSLPPINTVFMGTAAGGT", "length": 923 }, "evidence": [ { "id": "E1BFK8", "url": "https://omabrowser.org/oma/group/E1BFK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YF66-1", "protein_name": "DNA-binding protein RFX6", "gene_name": "RFX6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAKGPEQEEAFLHLPATQAMSAAAAPDECYAELLAGDLLPYAEEGLEDGRGLPELPAAIKSEVPFNGETLSSEEEDADTQDGKLRAADKSPSPKKSITQMMKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLLLQGCISKDKVDTLIMMYKTHCQCVLDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPIIVDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEILMDKKLPIARRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIEKVDLNSIGSQALLAVSGSTDTDGEVYNEYDSITVFQELKDLLKKNATVESFIEWLDTVVEQRVIKASKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNLDASKATFTASPSSCFLANRNKAASLPSDTSVKNECLVEQTYVSLSASQPSSMPSGLNPFATGDGENMQLTGQMELPQSTGHLMTPPISPALVSRGSVINQGPMAVRPPSVGPVLSTHSQCSSYSEPLYQTLSQTNQNYYGNNSSYQAMFRTQAHSTSGVYHHRAEHGRFNALNEHQFSRDYFNNSCAVTPYSARSPSSYCSSSMTQDAHNMQFLNTGSFNFLSNSAPTCPGATYPPNASNGYYGNNLNYPESHRLGSMVDQHVSVISSVSSIRSLPSYSDTHDPLNILDDSGRKQTGSYYTESSPSIVCRTAMSSNMQTTSSSQCMYGTSGQFTPQENLESHEPPNRGMVSSLPPINTVFMGAAAGGT", "length": 914 }, "evidence": [ { "id": "E1BFK8", "url": "https://omabrowser.org/oma/group/E1BFK8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8C7R7-1", "protein_name": "DNA-binding protein RFX6", "gene_name": "Rfx6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKVRELEEAFVQEQPSPQLPSEIAEECCAQLLGKGLLVYPEDSAYLLAETAAGARSSGEKGGDPGLQVGVKSEMQLNNGNFSSEEEDADTQESKTKAADPQLSQKKSITQMMKDKKKQTQLTLQWLEDNYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALIDKKIPILRRFVSSLKRQTSFLHLAQIARPALFDQHVVNAMVSDIEKVDLNSIGSQALLTISNSTDTESDIYSEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKMSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKASSLASDTVKNESHVETSYVPLPSSQPGAIPPALHPFSTEDTDNMPLPGQIELSQSTGHLMTPPISPAIASRGSVINQGPMASRPPSVGTVLSAPTHCSTYAEPIYPTLSPANHDFYGTNSNYQTMFRTQSHPASSLYAHRAEHGRCMAWTEQQLSRDFFGGSCAGSPYNCRPPSSYGPSTHTQESHSMQVLNTGSFNFLSNAGAGSCQGSTLPSNSPNGYYGNNINYSEAHRLGSMVNQHVSVISSVRSLPPYSDIHDPLNILDDSSRKQNNSFYADTLSPVACRTTVVASNLQTQIPSSSSQCMYGTSNQYPVQDSLDSNAASNREMVSSLPPINTVFMGTAAGDT", "length": 927 }, "evidence": [ { "id": "E1BFK8", "url": "https://omabrowser.org/oma/group/E1BFK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8HWS3-1", "protein_name": "DNA-binding protein RFX6", "gene_name": "RFX6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKVPELEDTFLQAQPAPQLSPGIQEDCCVQLLGKGLLVYPEETVYLAAEGQPGGEQGGGEKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQKKTITQIVKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNSIGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYLPLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCSTYPEPIYPTLPQANHDFYSTSSNYQTVFRAQPHSTSGLYPHHTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPPSSYGPSLQAQDSHNMQFLNTGSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHRLGSMVNQHVSVISSIRSLPPYSDIHDPLNILDDSGRKQTSSFYTDTSSPVACRTPVLASSLQTPIPSSSSQCMYGTSNQYPAQETLDSHGTSSREMVSSLPPINTVFMGTAAGGT", "length": 928 }, "evidence": [ { "id": "E1BFK8", "url": "https://omabrowser.org/oma/group/E1BFK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "regulation of insulin secretion", "id": "GO:0050796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050796", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "positive regulation of insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0035774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035774", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "pancreatic D cell differentiation", "id": "GO:0003311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003311", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "pancreatic epsilon cell differentiation", "id": "GO:0090104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090104", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "type B pancreatic cell differentiation", "id": "GO:0003309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003309", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" }, { "name": "pancreatic A cell differentiation", "id": "GO:0003310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003310", "evidence": [ { "database": "UniProtKB", "id": "E1BFK8", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFK8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 927, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFK8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFK8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFK8" }, { "id": "PS51526", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51526" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RFX-type winged-helix", "eco_id": "ECO_0000259", "start_pos": 123, "end_pos": 198, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 458, "end_pos": 460 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 590, "end_pos": 592 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGK1-1", "uniprot_ac": "E1BGK1", "uniprot_id": "E1BGK1_BOVIN", "mass": { "chemical_mass": 144871.0, "monoisotopic_mass": 144871.0 }, "refseq": { "ac": "XP_005211879", "name": "AT-rich interactive domain-containing protein 4A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211879" }, "gene_names": [ { "name": "ARID4A", "type": "recommended", "evidence": [ { "id": "E1BGK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ] }, { "name": "ARID4A", "type": "synonym", "evidence": [ { "id": "XP_005211879", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211879" } ] }, { "name": "RBBP1", "type": "synonym", "evidence": [ { "id": "XP_005211879", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211879" } ] } ], "protein_names": [ { "name": "AT-rich interactive domain-containing protein 4A", "type": "recommended", "evidence": [ { "id": "E1BGK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGK1/entry#names_and_taxonomy" } ] }, { "name": "AT-rich interactive domain-containing protein 4A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005211879", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211879" } ] }, { "name": "Retinoblastoma-binding protein 1", "type": "synonym", "evidence": [ { "id": "E1BGK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGK1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "DNA-binding protein which modulates activity of several transcription factors including RB1 (retinoblastoma-associated protein) and AR (androgen receptor). May function as part of an mSin3A repressor complex. Has no intrinsic transcriptional activity. Plays a role in the regulation of epigenetic modifications at the PWS/AS imprinting center near the SNRPN promoter, where it might function as part of a complex with RB1 and ARID4B. Involved in spermatogenesis, together with ARID4B, where it acts as a transcriptional coactivator for AR and enhances expression of genes required for sperm maturation. Regulates expression of the tight junction protein CLDN3 in the testis, which is important for integrity of the blood-testis barrier. Plays a role in myeloid homeostasis where it regulates the histone methylation state of bone marrow cells and expression of various genes involved in hematopoiesis. May function as a leukemia suppressor.", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1#function" }, { "database": "UniProtKB", "id": "ARBA00054828", "url": "https://www.uniprot.org/uniprotkb/ARBA00054828#function" }, { "database": "UniProtKB", "id": "A0AAA9SE50", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE50#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARID4A", "url": "https://www.uniprot.org/uniprotkb/E1BGK1", "locus": { "chromosome": "10", "start_pos": 70654759, "end_pos": 70592722, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018898", "url": "https://www.ensembl.org/id/ENSBTAG00000018898" } ] } } ], "crossref": [ { "id": "E1BGK1", "url": "https://alphafold.ebi.ac.uk/entry/E1BGK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018898", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018898", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16882", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16882", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18641", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18641", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20390", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20390", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "531515", "url": "https://www.ncbi.nlm.nih.gov/gene/531515", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BGK1", "url": "https://www.orthodb.org/?gene=E1BGK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13964:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13964:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3214815", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214815", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005211879", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211879", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SE50", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SE50-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGK1-1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPLRVGAIVETRTSDGSFQEAVISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETLDQLPLTNPEHFGTPVIAKKMNRGRRSSLPVNEDEKEEESSEEEDEDKRRLNDELLGKVVSVVSTSEKSEWYPALVISPSCNDDITVKKDQCLIRSFIDSKFYSIARKDIKEVDILNLPESELSAKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENEEEKEKEAKKEEEEMPEEEPDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDSIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTIHHHEPKVKEEKKDLEESMEEAPKVDQEMPLVEVKSEPEENIDSNSESEREEVELKSPRGRRRIARDANSIKKEIEEEKTEDKLRENDTENKDVDDDSETAEKKENELLLGRKNTPKQKEKKIRKQEDSDKDSEEEEEKSQEREETESKCDSEGEEDEEDTEPCLTGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSDGKSGTRSARSNRPDSSPLSNGMEDSCSSDSETEDLLEKNLMNEELSPDIKEELEKNENLNDDKLDEENPKTAPHILKENDRTQMQSLETLKLEAGENEQIVQILGNKVEQEEVKKDAEKSPKGKGRRSKTKDLSLEIIKISSFTQDEAGTEPHIDAQSPEFSSLDSKNFSSATEDETDQCAKEKKLKRKILGQSSPEKRIRIENGMEMTNSISSTSQERTSDCTASEGVKNLNFEQHFEIENEGMPSLIAEPNQCVQELTNEKFDGPAEETVNTPLKEEEDAMPLIGPETLVCHEVDLDDLDEKEKTSIEDAVVESSESNSLVSIPPALPPVAQHNFSVASPLTLSQDESRSIKSESDITIEVDSIAEESQEGLCERESANGFEASVASGTCSIIVQERESREKGQKRPSDGTSGLLAKKQKRTPKRTSAVAKNEKNGAGQSSDSEDLPVLDNSSKCTPVKHLSVSKPQKLARSPARISPHIKDGEKDKQKEKHPNSSPRTYKWSFQLNELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR", "length": 1281, "header": "tr|E1BGK1-1|E1BGK1_BOVIN Isoform 1 of AT-rich interactive domain-containing protein 4A OS=Bos taurus OX=9913 GN=ARID4A PE=4 SV=4 CANONICAL=E1BGK1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SE50-1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1/entry#A0AAA9SE50-1", "sequence": { "sequence": "MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPLRVGAIVETRTSDGSFQEAVISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETLDQLPLTNPEHFGTPVIAKKMNRGRRSSLPVNEDEKEEESSEEEDEDKRRLNDELLGKVVSVVSTSEKSEWYPALVISPSCNDDITVKKDQCLIRSFIDSKFYSIARKDIKEVDILNLPESELSAKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENEEEKEKEAKKEEEEMPEEEPDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDSIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTIHHHEPKVKEEKKDLEESMEEAPKVDQEMPLVEVKSEPEENIDSNSESEREEVELKSPRGRRRIARDANSIKKEIEEEKTEDKLRENDTENKDVDDDSETAEKKENELLLGRKNTPKQKEKKIRKQEDSDKDSEEEEEKSQEREETESKCDSEGEEDEEDTEPCLTGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSDGKSDSCSSDSETEDLLEKNLMNEELSPDIKEELEKNENLNDDKLDEENPKTAPHILKENDRTQMQSLETLKLEAGENEQIVQILGNKVEQEEVKKDAEKSPKGKGRRSKTKDLSLEIIKISSFTQDEAGTEPHIDAQSPEFSSLDSKNFSSATEDETDQCAKEKKLKRKILGQSSPEKRIRIENGMEMTNSISSTSQERTSDCTASEGVKNLNFEQHFEIENEGMPSLIAEPNQCVQELTNEKFDGPAEETVNTPLKEEEDAMPLIGPETLVCHEVDLDDLDEKEKTSIEDAVVESSESNSLVSIPPALPPVAQHNFSVASPLTLSQDESRSIKSESDITIEVDSIAEESQEGLCERESANGFEASVASGTCSIIVQERESREKGQKRPSDGTSGLLAKKQKRTPKRTSAVAKNEKNGADELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR", "length": 1192, "header": "tr|A0AAA9SE50-1|E1BGK1_BOVIN Computationally mapped isoform of AT-rich interactive domain-containing protein 4A OS=Bos taurus OX=9913 GN=ARID4A PE=4 SV=1 CANONICAL=E1BGK1-1" }, "locus": { "chromosome": "10", "start_pos": 70653000, "end_pos": 70594019, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118583.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118583.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084408.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084408.1" } ] } }, { "isoform_ac": "E1BGK1-1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1/entry#E1BGK1-1", "sequence": { "sequence": "MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPLRVGAIVETRTSDGSFQEAVISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETLDQLPLTNPEHFGTPVIAKKMNRGRRSSLPVNEDEKEEESSEEEDEDKRRLNDELLGKVVSVVSTSEKSEWYPALVISPSCNDDITVKKDQCLIRSFIDSKFYSIARKDIKEVDILNLPESELSAKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENEEEKEKEAKKEEEEMPEEEPDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDSIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTIHHHEPKVKEEKKDLEESMEEAPKVDQEMPLVEVKSEPEENIDSNSESEREEVELKSPRGRRRIARDANSIKKEIEEEKTEDKLRENDTENKDVDDDSETAEKKENELLLGRKNTPKQKEKKIRKQEDSDKDSEEEEEKSQEREETESKCDSEGEEDEEDTEPCLTGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSDGKSGTRSARSNRPDSSPLSNGMEDSCSSDSETEDLLEKNLMNEELSPDIKEELEKNENLNDDKLDEENPKTAPHILKENDRTQMQSLETLKLEAGENEQIVQILGNKVEQEEVKKDAEKSPKGKGRRSKTKDLSLEIIKISSFTQDEAGTEPHIDAQSPEFSSLDSKNFSSATEDETDQCAKEKKLKRKILGQSSPEKRIRIENGMEMTNSISSTSQERTSDCTASEGVKNLNFEQHFEIENEGMPSLIAEPNQCVQELTNEKFDGPAEETVNTPLKEEEDAMPLIGPETLVCHEVDLDDLDEKEKTSIEDAVVESSESNSLVSIPPALPPVAQHNFSVASPLTLSQDESRSIKSESDITIEVDSIAEESQEGLCERESANGFEASVASGTCSIIVQERESREKGQKRPSDGTSGLLAKKQKRTPKRTSAVAKNEKNGAGQSSDSEDLPVLDNSSKCTPVKHLSVSKPQKLARSPARISPHIKDGEKDKQKEKHPNSSPRTYKWSFQLNELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR", "length": 1281, "header": "tr|E1BGK1-1|E1BGK1_BOVIN Isoform 1 of AT-rich interactive domain-containing protein 4A OS=Bos taurus OX=9913 GN=ARID4A PE=4 SV=4 CANONICAL=E1BGK1-1" }, "locus": { "chromosome": "10", "start_pos": 70653000, "end_pos": 70594019, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025155.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025155.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025155.7", "url": "https://www.ensembl.org/id/ENSBTAP00000025155.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-3214815", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214815", "resource": "Reactome", "description": "HDACs deacetylate histones" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "E1BGK1", "url": "https://www.uniprot.org/uniprotkb/E1BGK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1026, "end_pos": 1028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1143, "end_pos": 1145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1186, "end_pos": 1188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1205, "end_pos": 1207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 858, "end_pos": 860, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGK1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1281, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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CANONICAL=E1BI43-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SEP6-1", "url": "https://www.uniprot.org/uniprotkb/E1BI43/entry#A0AAA9SEP6-1", "sequence": { "sequence": "MCSGLCLCCPAVGCDRTPSASPDLGKHSPLALLAATCSRIGQPGATAPPDFLQVSYDPALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKSHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPTCRQLSPNSAPDDLPWWSIPQAGSGPGTSGVPGGSLSGPCAGGPHAPRFPATAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDPRDL", "length": 394, "header": "tr|A0AAA9SEP6-1|E1BI43_BOVIN Computationally mapped isoform of Sp5 transcription factor OS=Bos taurus OX=9913 GN=SP5 PE=3 SV=1 CANONICAL=E1BI43-1" }, "locus": { "chromosome": "2", "start_pos": 25731938, "end_pos": 25729320, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104843.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104843.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082316.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082316.1" } ] } }, { "isoform_ac": "E1BI43-1", "url": "https://www.uniprot.org/uniprotkb/E1BI43/entry#E1BI43-1", "sequence": { "sequence": "MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGATAPPDFLQVSYDPALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKSHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPTCRQLSPNSAPDDLPWWSIPQAGSGPGTSGVPGGSLSGPCAGGPHAPRFPATAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDPRDL", "length": 397, "header": "tr|E1BI43-1|E1BI43_BOVIN Isoform 1 of Sp5 transcription factor OS=Bos taurus OX=9913 GN=SP5 PE=3 SV=3 CANONICAL=E1BI43-1" }, "locus": { "chromosome": "2", "start_pos": 25731210, "end_pos": 25729320, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004166.6", "url": "https://www.ensembl.org/id/ENSBTAT00000004166.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004166.5", "url": "https://www.ensembl.org/id/ENSBTAP00000004166.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512467", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512467", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUC1-1", "protein_name": "Sp5 transcription factor", "gene_name": "Sp5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAAPDFLQVPYDPALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPPTCRQLSPAPAPDDLPWWSIPQSGAGPGSSGVPGTSLSSACAGPPHAPRFPASAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKRENPRDL", "length": 398 }, "evidence": [ { "id": "E1BI43", "url": "https://omabrowser.org/oma/group/E1BI43/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A286ZUE4-1", "protein_name": "Sp5 transcription factor", "gene_name": "SP5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGATAPPEFLQVSYDPALGSPSRLFHPWTTDMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPTCRQLSPNPAPDDLPWWSIPQAGTGPGTSGVPGGSLSGPCAGGPHAPRFPASAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDPRDL", "length": 397 }, "evidence": [ { "id": "E1BI43", "url": "https://omabrowser.org/oma/group/E1BI43/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6BEB4-1", "protein_name": "Transcription factor Sp5", "gene_name": "SP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAPPDFLQVPYDPALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPPTCRQLSPNPAPDDLPWWSIPQAGAGPGASGVPGSGLSGACAGAPHAPRFPASAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL", "length": 398 }, "evidence": [ { "id": "E1BI43", "url": "https://omabrowser.org/oma/group/E1BI43/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JHX2-1", "protein_name": "Transcription factor Sp5", "gene_name": "Sp5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAAPDFLQVPYDPALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPPTCRQLSPAPAPDDLPWWSIPQSGAGPGSSGVPGTSLSSACAGPPHAPRFPASAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKRENPRDL", "length": 398 }, "evidence": [ { "id": "E1BI43", "url": "https://omabrowser.org/oma/group/E1BI43/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BI43", "url": "https://www.uniprot.org/uniprotkb/E1BI43" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": 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"https://www.uniprot.org/uniprotkb/E1BI43" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BI43", "url": "https://www.uniprot.org/uniprotkb/E1BI43" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BI43", "url": "https://www.uniprot.org/uniprotkb/E1BI43" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BI43", "url": "https://www.uniprot.org/uniprotkb/E1BI43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BI43-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 397, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BI43-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BI43" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BI43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI43" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 295, "end_pos": 324, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK89-1", "uniprot_ac": "E1BK89", "uniprot_id": "E1BK89_BOVIN", "mass": { "chemical_mass": 219131.0, "monoisotopic_mass": 219131.0 }, "refseq": {}, "gene_names": [ { "name": "LCT", "type": "recommended", "evidence": [ { "id": "E1BK89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ] } ], "protein_names": [ { "name": "Lactase/phlorizin hydrolase", "type": "recommended", "evidence": [ { "id": "E1BK89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK89/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.108", "type": "synonym", "evidence": [ { "id": "E1BK89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK89/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.62", "type": "synonym", "evidence": [ { "id": "E1BK89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK89/entry#names_and_taxonomy" } ] }, { "name": "Lactase/glycosylceramidase", "type": "synonym", "evidence": [ { "id": "E1BK89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK89/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Broad specificity glycosidase of the intestinal brush border membrane that hydrolyzes lactose, the main sugar in mammalian milk, to produce D-glucose and D-galactose. The mature protein is composed of two domains that catalyze the hydrolysis of beta-glucopyranosides and beta-galactopyranosides, with a preference for hydrophilic aglycones (in lactose and cellobiose) for one domain and hydrophobic aglycones (in phlorizin and glycosylceramides) for the other.", "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89#function" }, { "database": "UniProtKB", "id": "ARBA00058345", "url": "https://www.uniprot.org/uniprotkb/ARBA00058345#function" }, { "database": "UniProtKB", "id": "A0AAA9SFJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFJ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LCT", "url": "https://www.uniprot.org/uniprotkb/E1BK89", "locus": { "chromosome": "2", "start_pos": 61584840, "end_pos": 61534827, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015170", "url": "https://www.ensembl.org/id/ENSBTAG00000015170" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015170", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015170", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AHWAEPK", "url": "https://omabrowser.org/oma/group/AHWAEPK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BK89", "url": "https://www.orthodb.org/?gene=E1BK89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10353:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10353:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00232", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-189085", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189085", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "10076", "url": "https://www.rhea-db.org/rhea/10076", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "30679", "url": "https://www.rhea-db.org/rhea/30679", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69639", "url": "https://www.rhea-db.org/rhea/69639", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69647", "url": "https://www.rhea-db.org/rhea/69647", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69655", "url": "https://www.rhea-db.org/rhea/69655", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69659", "url": "https://www.rhea-db.org/rhea/69659", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69663", "url": "https://www.rhea-db.org/rhea/69663", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69667", "url": "https://www.rhea-db.org/rhea/69667", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69671", "url": "https://www.rhea-db.org/rhea/69671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69675", "url": "https://www.rhea-db.org/rhea/69675", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69679", "url": "https://www.rhea-db.org/rhea/69679", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69683", "url": "https://www.rhea-db.org/rhea/69683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69687", "url": "https://www.rhea-db.org/rhea/69687", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69699", "url": "https://www.rhea-db.org/rhea/69699", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69703", "url": "https://www.rhea-db.org/rhea/69703", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69707", "url": "https://www.rhea-db.org/rhea/69707", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69711", "url": "https://www.rhea-db.org/rhea/69711", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SFJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SFJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK89-1", "url": "https://www.uniprot.org/uniprotkb/E1BK89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELAWHLVLTVLLSFSCWGLDWDSDKNFISAAGPLTNSLLHDLRDPLGNQASPFVAEDEEIYVCRQPLPAFLPEYFRSVRASMITHYKVFLPWAQLLPEGISENPDKETVLCYRQLLEALKTAQLQPLVVLHHQTLPASTLQRTETFADLFAAYASFAFHSFGDLVEIWFTFSDLERVITKLPHQESRSSRLQMLTDAHRKAYEIYHEKYASQGGKLSVVLRAEMLSKLLLEPSMSTLVKDAVDFISLDLSYECHSEADLPQTLSELQTTEPKVKVFVFSLKLQNCLSTRNNVAHLLFSLLKAINEDQMLVIGFDISTFLSCSSSSKKSWSCSLSDSLTLQTAPQLGPDTAVYAWSPRSAYQRVWEAFANQSKAERDAFLQDVFPEGFLWGVSTGAFNVEGGWAEDGRGPSIWDRVGHQNTNKGQATPEVASDSYHKADTDVALLRGLQAQVYKFSISWSRIFPTGQGRNPNPRGVAYYNKLIDSLLDSHIEPMATLFHWDLPQALQDRGGWQSEDVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHAPGISDPGVASFKVAHMVLKAHARAWHHYNSHHRPQQQGRVGIVLNSDWAEPLSPERPEDLRAAERFLHFMLGWFAHPIFVDGDYPAALRAQIQQMNKQCPSPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISKARGDTCIPSYDTIGGFSQHVDPTWPQTASPWIRVVPWGIRRLLNFVSLEYTKGKVPIYLAGNGMPIGESEDLIDDSLRVDYFNQYINEVLKAIKEDSVVVQSYIARSFIDGFEGPSGYSQRFGLYHVNFDDSSRPRTARKSAYFFTSMIEKNGFLNKVVKRQSPPSIANVPRKIRAFSFPSEVPSKAKVVWEKFSNQPKFERDLFYHGTFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDVACDSYNHLDADLNMLQALKVKAYRFSISWSRIFPTGRNTSVNAHGVDYYNKLINGLVENNISPMVTLFHWDLPQALQDIGGWENPLLVDLFNSYADFCFQTFGDRVKFWMTFNEPTYQAWLGYGSGEFPPNVNDSGSGPYRIGHAIIKAHARVYHTYDEKYRQEQKGVISLSLSSHWAEPQSLVPRDVEAADRMLQFSLGWFAHPIFRNGDYPDAMKWKVGNRSELQHLATSRLPSFTEEEKQYIAATADVFCLNTYSSRIVQHTTPRLNPPSYTSDQELLEWEDTSWPATAMNRAAAWGMRRLLNWIKEEYGDIPVYITENGVGLTDPKLEDTDRIFYHKTYINEALKAYRLDGVNLRGYAAWSLMDNFEWLNGYTVKFGLYHVDFDDVNKSRTARASARYYTEVITNNGMPLSKEDEFLYGQFPKDFIWSAATASYQIEGAWRADGKGLSIWDTFSHTPLKVENNDTGDVACDSYHKIAEDLAALQTLGVTHYRFSISWTRILPDGTNRYINEAGLDYYVRLIDTLLAANIQPQVTIYHWDLPQALQDVGGWENETIVQRFKEYAEVLFQRLGDKVKFWITLNEPYVVAYQGYGYGTAAPGISFRPGTAPYIVGHNLIKAHAEAWHLYNDVYRARQGGVISITISSDWAEPRDPSNQEDVEAAKRYVQFMGGWFAHPIFKNGDYPEVMKTRIRDRSLAEGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYASWISSFDADRGVASITDRSWPDSGSFWLKMTPFGFRRILNWLKEEYNNPPIYVTENGVSHRGEANLNDTARIYYLRSYINEALKAAMQDKVDLRGYTVWTLMDNFEWATGFSDKFGLHFVNYTDPALPRIPRESAKVYASIIRCSGFPDPAAGPHPCLQQEDAEPTASPVRQNIQFLGLRLSTTEAQTALNVLFAFMLLGVCCVALLSYKYFKRSKQKHTQPGEQELSHRSSF", "length": 1928, "header": "tr|E1BK89-1|E1BK89_BOVIN Isoform 1 of Lactase/phlorizin hydrolase OS=Bos taurus OX=9913 GN=LCT PE=1 SV=3 CANONICAL=E1BK89-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SFJ4-1", "url": "https://www.uniprot.org/uniprotkb/E1BK89/entry#A0AAA9SFJ4-1", "sequence": { "sequence": "MELAWHLVLTVLLSFSCWGLDWDSDKNFISAAGPLTNSLLHDLRDPLGNQASPFVAEDEEIYVCRQPLPAFLPEYFRSVRASMITHYKVFLPWAQLLPEGISENPDKETVLCYRQLLEALKTAQLQPLVVLHHQTLPASTLQRTETFADLFAAYASFAFHSFGDLVEIWFTFSDLERVITKLPHQESRSSRLQMLTDAHRKAYEIYHEKYASQGGKLSVVLRAEMLSKLLLEPSMSTLVKDAVDFISLDLSYECHSEADLPQTLSELQTTEPKVKVFVFSLKLQNCLSTRNNVAHLLFSLLKAINEDQMLVIGFDISTFLSCSSSSKKSWSCSLSDSLTLQTAPQLGPDTAVYAWSPRSAYQRVWEAFANQSKAERDAFLQDVFPEGFLWGVSTGAFNVEGGWAEDGRGPSIWDRVGHQNTNKGQATPEVASDSYHKADTDVALLRGLQAQVYKFSISWSRIFPTGQGRNPNPRGVAYYNKLIDSLLDSHIEPMATLFHWDLPQALQDRGGWQSEDVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHAPGISDPGVASFKVAHMVLKAHARAWHHYNSHHRPQQQGRVGIVLNSDWAEPLSPERPEDLRAAERFLHFMLGWFAHPIFVDGDYPAALRAQIQQMNKQCPSPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISKARGDTCIPSYDTIGGFSQHVDPTWPQTASPWIRVVPWGIRRLLNFVSLEYTKGKVPIYLAGNGMPIGESEDLIDDSLRVDYFNQYINEVLKAIKEDSVVVQSYIARSFIDGFEGPSGYSQRFGLYHVNFDDSSRPRTARKSAYFFTSMIEKNGFLNKAKVVWEKFSNQPKFERDLFYHGTFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDVACDSYNHLDADLNMLQALKVKAYRFSISWSRIFPTGRNTSVNAHGVDYYNKLINGLVENNISPMVTLFHWDLPQALQDIGGWENPLLVDLFNSYADFCFQTFGDRVKFWMTFNEPTYQAWLGYGSGEFPPNVNDSGSGPYRIGHAIIKAHARVYHTYDEKYRQEQKGVISLSLSSHWAEPQSLVPRDVEAADRMLQFSLGWFAHPIFRNGDYPDAMKWKVGNRSELQHLATSRLPSFTEEEKQYIAATADVFCLNTYSSRIVQHTTPRLNPPSYTSDQELLEWEDTSWPATAMNRAAAWGMRRLLNWIKEEYGDIPVYITENGVGLTDPKLEDTDRIFYHKTYINEALKAYRLDGVNLRGYAAWSLMDNFEWLNGYTVKFGLYHVDFDDVNKSRTARASARYYTEVITNNGMPLSKEDEFLYGQFPKDFIWSAATASYQIEGAWRADGKGLSIWDTFSHTPLKVENNDTGDVACDSYHKIAEDLAALQTLGVTHYRFSISWTRILPDGTNRYINEAGLDYYVRLIDTLLAANIQPQVTIYHWDLPQALQDVGGWENETIVQRFKEYAEVLFQRLGDKVKFWITLNEPYVVAYQGYGYGTAAPGISFRPGTAPYIVGHNLIKAHAEAWHLYNDVYRARQGGVISITISSDWAEPRDPSNQEDVEAAKRYVQFMGGWFAHPIFKNGDYPEVMKTRIRDRSLAEGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYASWISSFDADRGVASITDRSWPDSGSFWLKMTPFGFRRILNWLKEEYNNPPIYVTENGVSHRGEANLNDTARIYYLRSYINEALKAMQDKVDLRGYTVWTLMDNFEWATGFSDKFGLHFVNYTDPALPRIPRESAKVYASIIRCSGFPDPAAGPHPCLQQEDAEPTASPVRQNIQFLGLRLSTTEAQTALNVLFAFMLLGVCCVALLSYKYFKRSKQKHTQPGEQELSHRSSF", "length": 1898, "header": "tr|A0AAA9SFJ4-1|E1BK89_BOVIN Computationally mapped isoform of Lactase/phlorizin hydrolase OS=Bos taurus OX=9913 GN=LCT PE=1 SV=1 CANONICAL=E1BK89-1" }, "locus": { "chromosome": "2", "start_pos": 61583836, "end_pos": 61535026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107831.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107831.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082377.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082377.1" } ] } }, { "isoform_ac": "E1BK89-1", "url": "https://www.uniprot.org/uniprotkb/E1BK89/entry#E1BK89-1", "sequence": { "sequence": "MELAWHLVLTVLLSFSCWGLDWDSDKNFISAAGPLTNSLLHDLRDPLGNQASPFVAEDEEIYVCRQPLPAFLPEYFRSVRASMITHYKVFLPWAQLLPEGISENPDKETVLCYRQLLEALKTAQLQPLVVLHHQTLPASTLQRTETFADLFAAYASFAFHSFGDLVEIWFTFSDLERVITKLPHQESRSSRLQMLTDAHRKAYEIYHEKYASQGGKLSVVLRAEMLSKLLLEPSMSTLVKDAVDFISLDLSYECHSEADLPQTLSELQTTEPKVKVFVFSLKLQNCLSTRNNVAHLLFSLLKAINEDQMLVIGFDISTFLSCSSSSKKSWSCSLSDSLTLQTAPQLGPDTAVYAWSPRSAYQRVWEAFANQSKAERDAFLQDVFPEGFLWGVSTGAFNVEGGWAEDGRGPSIWDRVGHQNTNKGQATPEVASDSYHKADTDVALLRGLQAQVYKFSISWSRIFPTGQGRNPNPRGVAYYNKLIDSLLDSHIEPMATLFHWDLPQALQDRGGWQSEDVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHAPGISDPGVASFKVAHMVLKAHARAWHHYNSHHRPQQQGRVGIVLNSDWAEPLSPERPEDLRAAERFLHFMLGWFAHPIFVDGDYPAALRAQIQQMNKQCPSPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISKARGDTCIPSYDTIGGFSQHVDPTWPQTASPWIRVVPWGIRRLLNFVSLEYTKGKVPIYLAGNGMPIGESEDLIDDSLRVDYFNQYINEVLKAIKEDSVVVQSYIARSFIDGFEGPSGYSQRFGLYHVNFDDSSRPRTARKSAYFFTSMIEKNGFLNKVVKRQSPPSIANVPRKIRAFSFPSEVPSKAKVVWEKFSNQPKFERDLFYHGTFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDVACDSYNHLDADLNMLQALKVKAYRFSISWSRIFPTGRNTSVNAHGVDYYNKLINGLVENNISPMVTLFHWDLPQALQDIGGWENPLLVDLFNSYADFCFQTFGDRVKFWMTFNEPTYQAWLGYGSGEFPPNVNDSGSGPYRIGHAIIKAHARVYHTYDEKYRQEQKGVISLSLSSHWAEPQSLVPRDVEAADRMLQFSLGWFAHPIFRNGDYPDAMKWKVGNRSELQHLATSRLPSFTEEEKQYIAATADVFCLNTYSSRIVQHTTPRLNPPSYTSDQELLEWEDTSWPATAMNRAAAWGMRRLLNWIKEEYGDIPVYITENGVGLTDPKLEDTDRIFYHKTYINEALKAYRLDGVNLRGYAAWSLMDNFEWLNGYTVKFGLYHVDFDDVNKSRTARASARYYTEVITNNGMPLSKEDEFLYGQFPKDFIWSAATASYQIEGAWRADGKGLSIWDTFSHTPLKVENNDTGDVACDSYHKIAEDLAALQTLGVTHYRFSISWTRILPDGTNRYINEAGLDYYVRLIDTLLAANIQPQVTIYHWDLPQALQDVGGWENETIVQRFKEYAEVLFQRLGDKVKFWITLNEPYVVAYQGYGYGTAAPGISFRPGTAPYIVGHNLIKAHAEAWHLYNDVYRARQGGVISITISSDWAEPRDPSNQEDVEAAKRYVQFMGGWFAHPIFKNGDYPEVMKTRIRDRSLAEGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYASWISSFDADRGVASITDRSWPDSGSFWLKMTPFGFRRILNWLKEEYNNPPIYVTENGVSHRGEANLNDTARIYYLRSYINEALKAAMQDKVDLRGYTVWTLMDNFEWATGFSDKFGLHFVNYTDPALPRIPRESAKVYASIIRCSGFPDPAAGPHPCLQQEDAEPTASPVRQNIQFLGLRLSTTEAQTALNVLFAFMLLGVCCVALLSYKYFKRSKQKHTQPGEQELSHRSSF", "length": 1928, "header": "tr|E1BK89-1|E1BK89_BOVIN Isoform 1 of Lactase/phlorizin hydrolase OS=Bos taurus OX=9913 GN=LCT PE=1 SV=3 CANONICAL=E1BK89-1" }, "locus": { "chromosome": "2", "start_pos": 61583836, "end_pos": 61535026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020185.6", "url": "https://www.ensembl.org/id/ENSBTAT00000020185.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020185.5", "url": "https://www.ensembl.org/id/ENSBTAP00000020185.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-189085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189085", "resource": "Reactome", "description": "Digestion of dietary carbohydrate" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z4Y3-1", "protein_name": "Lactase", "gene_name": "LCT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MELVCKTVVFFLLVSTSLGIDEELAQDFVAIAGPLPTTLAHRLHLQSHILPKEALDPTVSEAHDDFCQQDTVISQLPQYFSHLREIGVTHYKVFLPWARILPDGDAKKPDEAQVRCYQELLKMLVAADLRPVIVLHHKGVPDTVAVGRKASSFADLFVDYAEFSFYVFGGLADMWLTFSDLPELLESLPYSDSQVRVQALAAAHERAYSVYHKKYSGGKLSIALGMDLILDSTSSELLSVSFQESVDFLSLSLQYWCGNETDFYLKMSEFQNVWKDTEVLLFSLKFLDCGSLEENPFIPVAAIVAAINKEKARTIGYDVNEFLDFSSRVLSKAYTLQENLSAAIAPRSSYQTVWEMFANQSELERDTFLQDVFPSGFLWGTSTGAFNIEGAWAEDGKGESIWDQFGHEGHVYMNQTTDVACDSYHKTSYDVYLLRGLHPQLYKFSISWPRIFPAGTNETIGFKGVDYYNQLIDRLLEANIEPMVTLFHWDLPQALQVLGGWQNDSIIDAFANYADFCFTTFGDRVKFWVTFHEPWVISYAGYGTGEHPPGITDPGIASYKVAHTILKAHAKVWHLYNDRYRSQQQGRVGLVLNSDWAEPQTPANSEDVKASERYLQFMLGWFAHPVFVNGDYPDILKAQIQEVNQQCSTTVAQLPVFTEEEKTWVKGTADFFGLSHYTSHLVTAVTNGTCTPGYESIGNFSLHVDPSWPKTASSSIHVVPWGLRRLLKFVSQEYTGTKIPIYIAGNGMPTEAVGDLINDTLRVDYFRRYINEALKAIKLDAVDVQSYIARSLIDGFEGPGGYSLKFGLHHVNFEDSNRPRTPKASAYFYSSVIENNGFPSKVSDRSSTSVVFGLPTPSKLPSLPASEVPSKSKVVWQKFSSQTDFERDMYVYGTFPKDFTWGVSSSAYQIEGGWDADGKGPSVWDNFTHVPGNIKNNDTGDIACNSYNKVEEDIYLLRALGVKNYRFSLSWPRIFPNGRNNSINSHGVDYYNRLIDGLVANNITPIVTLYHWDLPQALQDIGGWENSELIELFDSFADFCFQTFGDRVKFWLTFNEPQVIAWVSYGTGEFPPNVNNPGSAPYEVAHTLLKAHARVYHTYDDKYRASQGGVISLCLNIDWIEPKTPSNPRDLEAADRYMQFLVGWFAHPVFKNGDYPEVMKWTVGNRSELQNLPSSRLPVFTAEEREYIRGTADVFCLNTYTAKLVTHATTRLNPFSYEYDQEISTDVDSSWPTSALAGHRAVAWGLRRLLNWVKEEYGNPPMYIIENGVGIKTKSDVDDHTRILYYKTYIDEALKAYKLDGVNLRGYNAWSFMDFFEWLNGYEPRFGLHEVDFNDPNRPRTPRRSAVYYAEIIRNNGIPLPEENKFLYGEFPKNFCWSVATAAYQIEGAWRADGKGLSIWDKYTHTPLKISNDDNGDVACDSYHKIEEDVEMLKRLKVSHYRFSISWSRVLPDGTTRYINEMGLNYYERLIDALLAANITPQVTLYHWDLPQALQDIGGWENDTIVQRFKEYAELLFQRLGDKVKFWITLNEPYNTAYLGYGFGTAAPGISVRPGRAPYVVGHNLIKAHAEAWHLYNETYRAKQGGLISITINSDWAEPRNPHKQEDFDAARQYLQFLIGWFAHPIFKNGDYNEVMKTRIRERSLAQGLSSSRLPEFTESEKQRIKGTYDYFGLNHYTTVLAYKYEYSTGILSYDADRGVASVTDRSWLNSGSFWLKVTPFGFRKLLRWIKEEYNNPPIYVTENGVSERGAIDFNDTWRIHYYQNYINEALKAVVLDGVDLRGYTAWTLMDNFEWAVGYDERFGFYHVNYTDPTLPRLPKASTRYYSQIISCNGFPDPATGPHPCLETEPDVIPDTTPGLADSVRFLGLDLTSQRAEIALYVLFALSAIGALGLALISYKYGTISKRYHKQSSMELSKM", "length": 1919 }, "evidence": [ { "id": "E1BK89", "url": "https://omabrowser.org/oma/group/E1BK89/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1Q8B5-1", "protein_name": "Lactase/phlorizin hydrolase isoform X1", "gene_name": "LOC559107", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMKILGGFLSLGVLAIFWSYINADEQEFMLLAGPLTTSQNLPSEEQYVFNCRGPLPQQSKDYFLYLQRRGVTNFKVLLSWSHILPTGDANQPHEETVMCFKTLVQQLTESGIKPLLVLHRSAVPELFRAKYGGWGNPLLVQIFEQYAGFVFSTFRDHVDTFVTFSHLHELQHEELQNALQSHENAYKVCHQQFKGLRLSLGIRASHATSIYQMGSKIMTHVDFLSVHMQFNCKMQTALTEELRKVQIVSGQKSLLIYQLTVNDCDGYEHDFQPLTVVLGVLQNKDYKIIGCDITHVFEKLDYEETPRSLQKEDAMSVFNQKSASAFSYQKVWEKFKTQTEAERDQFLSGSFPVDFEWSVSSESFKVEGGSAEHGKGETIWDRFNHEAGVNESILGCDSYHKVDYDVYLLRGMMAPNYQFSISWARIFPTGRKESFVEKGAAYYDKMINTLLQSGIEPTVTLHHWDLPQALQESGGWINDSIVEAFKEFSDFCFSRYGDRVKTWVTFGSPWVVSNLGYGTGVYPPSIKDPVSASYKVTHNILKSHAEAWHIYNDKYRKLYGGKVGIALNSDWAEPRDPSSDQDVAAAERYLNFMLGWFAHPIFVDGDYPAVLREQIEKKKKLCDQDLARLPVFTEAEKQRIQGTADFFGLNHQTSRLISENLTSCDAGPDNVGDFQAHIDPTWPTTSSDQIQSVPWGLRRLLYYIFLEYTSITKVPIYITGNGMPTEYTGDGINDTLRVDYLKAYINEAMKAVHLDDVVVQRFTVQSLMDGYEGPPGYTQRFGLHYVNFDDPDRPRTPKASAYYYSKVIERNGFAETAASPKMQIHGNQVESRRLPSLPPSQVPSKSKVVWEKFSPQTKFERQLYHYGTFSEGFQWGVSSSAYQVEGGWNADGKGPSVWDTFTQKPGNIPNNANGDVACDSYNKVDEDLHMLRALKVKTYRFSLSWSRIFPNGYKSSLNQKGVDYYNRLIDGLIANNITPMVTLYHWDLPQALQNIHWDNTEMIGLFNEYCDFCYATFGDRVKFWITFNEPQTIAWLGYGLGQIPPNVKQPGDAPYRVAHNLLKAHAQAYHTYDEKYRASQGGLVSISLNAEWAEPLDVNIPREVVAADRALQFQLGWFAHPIFKNGDYPEAMKWQVGNKSELQGLKESRLPHFTDQEKAFIQGTADVFCINTYTTKVVRHVTSRLNIESYQTDQDIEKDKADGSENTAVSEQKAVAWGLRRLLIWLKEEYGNPEIYITENGVATGTAITTDDTDRIFYLKTYVDEALKAHNLDGVRVKGYIASSLMDSFEWLNGYNVGYGLHHVDFKHSSRPRTPKRSAHLYFDIMRNNGFPMPVEEKMLYGHFREGFVWSTATAAYQIEGAWRADGKGLSIWDKFAHTSLKISQDENGDIACDSYNKIEEDIDNLKTLRVNHYRFSISWPRILPDGTNRKINEAGLNYYHRLIDVLLAANIKPQVTLYHWDLPQALQDVGGWENDTIVDRFKDYADVVFNSLGDKVEFWITINEPYNVAMVGHGYGSAAPGITFRPGTAPYIVAHNLIKAHAEAWHLYNDKYRAKHGGIVGITINSDWAEPRNPYKQEDVDAARRVVQFQLGWFAHPVFNGDYSDLMKDIVRERSLAAGLPKSRLPEFTPEEVARIKGTHDYFGFNHYTTVLAYNFDYKDLQHYDADRGVGTVTDRTWLDSGSFWLKVTPVGFRKILNFIKEEYGDHTIYITENGVSERGPVNLNDIPRIHYYDNYINQALKAYMLDGVDIRGYAAWTLMDNLEWATGFDDRFGLFYVNRSDPNLPRIPKKSVWNYATIINCNGFISPEERPHKCQVHEPEDDTPGITTIPPPVEELSISFLGLEVSVSDAELALNVLFSLSIIAAVTVILLVYGLVKASKKQKHPAGEYIDLEKKDKF", "length": 1900 }, "evidence": [ { "id": "E1BK89", "url": "https://omabrowser.org/oma/group/E1BK89/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F8VPT3-1", "protein_name": "Lactase/phlorizin hydrolase", "gene_name": "Lct", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELPWTALFLSTFLLGLSCQGNDWESDRNFISAAGPLTNDLVHNLNHPLGKQGSDLVAGDTDIYVCQQPLPSFLPQYFSSLRASQVTHYKVLLSWAQLLPKGSSKNPDQEAVQCYRQLLQSLKDAQLQPMVVLFHQMPPTSTIQRDGGFADLFADYATLAFQSFGDLVEIWFTFSDLEKVIMGLPHQHLKASGLQTLSDAHRKAFDVYHRKYSSQGGKLSVVLKAEDLPKLLPDPSSAALVKGSVDFLSLDLSYDCQSISTLPQKLSELQNLEPKVKVFVYTLKPQDCPSTGMSPASLLFRLLEAINKDQVQTVGFDVSAFLSCTSSSEESPSCSLTYSSLALQSEQQHETVVSSFPGSAYQRVWAALANQSREERDAFLQDVFPEGFLWGVSTGAFNVEGGWAEGGRGPSIWDHYSNLNAAESQATAKVASDSYHKPVSDVALLRGLRADVYKFSISWSRIFPFGQRTSPNLQGVAYYNKLIDSLLDSQVEPMATLFHWDLPQALQEQGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVISYAGYGTGQHAPAISDPGVASFKVAHLILKAHARTWHHYNYHHRQKQQGRVGIVLNSDWAEPLDGKSPQDLAAAERYLHFMLGWFAHPIFIDGDYPAALRAQIQHTNQQCGRPLAQLPEFTEAEKRLLKGSADFLGLSHYTSRLISKAGQQTCIPSYDNIGGFSQHVDPKWPQTASPWIRVVPWGIRRLLRFASLEYTKGKLPIFLAGNGMPIGEGSDLFDDSMRVNYLNLYINEVLKAVKEDSVDVRSYIARSLIDGYEGPLGYSQRFGLYHVNFNDSSRPRTPRKSAYFFTSIIEKNGFPAKKVKRNPLPLKADFSSRARAAFSFPSEVPSKAKVVWEKFSRQPKFERDLFYHGTFRDDFLWGVSSSAYQIEGGWDADGKGPSIWDNFTHTPGNGVKDNATGDIACDSYHQLDADINILRTLKVKSYRFSISWPRIFPTGRNSSINKQGVDYYNKLIDRLLESNIFPMVTLFHWDLPQALQDIGGWENPSLIELFDSYADFCFKTFGDRVKFWMTFNEPWCSAVLGYSSGIFPPNVQDPGSLSYKVSHVIIKAHARVYHTYDEKYRQEQKGVISLSLNTHWVEPKDPGVQRDVEAADRMLQFNLGWFAHPIFKNGDYPDVMKWNVGNRSELQHLASSRLPSFTEEEKNYIRGTADVFCINTYTSVFAQHVTPRLNPPSYDNDMELKASDMNSSALISMMHQDVPWGMRRLLNWIKEEYGNIPIYITENGQGLTNPTLDDTERIFYHKTYINEALKAYRLDGVDLRGYSAWALMDNFEWLHGYTMRFGLYHVDFDHVNRPRTARASARYYTEVITNNGMPLAKEDEFLYGEFPKGFIWSAASASYQVEGAWRADGKGLSIWDTFSHTPLKIGNDDNGDVACDSYHKIAEDVVALQNLGVSHYRFSISWPRILPDGTTKFINEAGLNYYVRFIDALLAAGITPQVTMYHWDLPQALQDVGGWENETVVQRFKDYADVLFRRLGDKVKFWITLNEPFVIAAHGYGSGVSAPGISFRPGTAPYTAGHNLIKAHAEAWHLYNSTYRNSQGGVISITISSDWAEPRDPSNQEDVEAARRYVQFMGGWFAHPIFKNGDYPEVMKTRIRDRSLAAGLNKSRLPEFTESEKKKIQGTFDFFGFNHYTTVLAYNLNYAAAVSSFDADRGVASITDRSWPDSGSFWLKMTPFGFRRILNWLKEEYNNPLIYVTENGVSRRGDPELNDTDRIYYLRSYINEALKAVRDKVDLRGYTVWSIMDNFEWATGFAERFGVHFVNRSDPSLPRIPKASAKVYASIVRCNGFPDPAQGPHPCLQQPEDAGPTASPVKSEVPFLGLMLGTAEAQTALYVLFALVLLGVCSVAFLLYKYCKRSKQGTTQPGHHGLSQISSF", "length": 1931 }, "evidence": [ { "id": "E1BK89", "url": "https://omabrowser.org/oma/group/E1BK89/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P09848-1", "protein_name": "Lactase/phlorizin hydrolase", "gene_name": "LCT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELSWHVVFIALLSFSCWGSDWESDRNFISTAGPLTNDLLHNLSGLLGDQSSNFVAGDKDMYVCHQPLPTFLPEYFSSLHASQITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEAFADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQLQTLSDAHRKAYEIYHESYAFQGGKLSVVLRAEDIPELLLEPPISALAQDTVDFLSLDLSYECQNEASLRQKLSKLQTIEPKVKVFIFNLKLPDCPSTMKNPASLLFSLFEAINKDQVLTIGFDINEFLSCSSSSKKSMSCSLTGSLALQPDQQQDHETTDSSPASAYQRIWEAFANQSRAERDAFLQDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTTEGQATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPGISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGIVLNSDWAEPLSPERPEDLRASERFLHFMLGWFAHPVFVDGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQHVNHVWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIEKNGFLTKGAKRLLPPNTVNLPSKVRAFTFPSEVPSKAKVVWEKFSSQPKFERDLFYHGTFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDPGWAPYRIAHAVIKAHARVYHTYDEKYRQEQKGVISLSLSTHWAEPKSPGVPRDVEAADRMLQFSLGWFAHPIFRNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYEDDQEMAEEEDPSWPSTAMNRAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGMPLAREDEFLYGRFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHTPLRVENDAIGDVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPGVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSDWAEPRDPSNQEDVEAARRYVQFMGGWFAHPIFKNGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDADRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVRCNGFPDPATGPHACLHQPDAGPTISPVRQEEVQFLGLMLGTTEAQTALYVLFSLVLLGVCGLAFLSYKYCKRSKQGKTQRSQQELSPVSSF", "length": 1927 }, "evidence": [ { "id": "E1BK89", "url": "https://omabrowser.org/oma/group/E1BK89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q02401-1", "protein_name": "Lactase/phlorizin hydrolase", "gene_name": "Lct", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"length": 1928 }, "evidence": [ { "id": "E1BK89", "url": "https://omabrowser.org/oma/group/E1BK89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ], "pmid": "" }, { "name": "lactose catabolic process", "id": "GO:0005990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005990", "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ], "pmid": "" }, { "name": "quercetin catabolic process", "id": "GO:1901733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901733", "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ], "pmid": "" }, { "name": "cellobiose catabolic process", "id": "GO:2000892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000892", "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ], "pmid": "" }, { "name": "external side of apical plasma membrane", "id": "GO:0098591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098591", "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "lactase activity", "id": "GO:0000016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000016", "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ], "pmid": "" }, { "name": "beta-glucosidase activity", "id": "GO:0008422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008422", "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ], "pmid": "" }, { "name": "phlorizin hydrolase activity", "id": "GO:0140749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140749", "evidence": [ { "database": "UniProtKB", "id": "E1BK89", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1013, "end_pos": 1015, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1086, "end_pos": 1088, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1175, "end_pos": 1177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1344, "end_pos": 1346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1420, "end_pos": 1422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1509, "end_pos": 1511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1657, "end_pos": 1659, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1673, "end_pos": 1675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1762, "end_pos": 1764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1816, "end_pos": 1818, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 936, "end_pos": 938, "annotation": "n_glycosylation_sequon" }, { "start_pos": 948, "end_pos": 950, "annotation": "n_glycosylation_sequon" }, { "start_pos": 991, "end_pos": 993, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10076", "name": "", "equation": "lactose + H2O = beta-D-galactose + D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "10076", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10076" } ] }, { "id": "30679", "name": "", "equation": "D-cellobiose + H2O = beta-D-glucose + D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "30679", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30679" } ] }, { "id": "69639", "name": "", "equation": "phlorizin + H2O = phloretin + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69639", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69639" } ] }, { "id": "69647", "name": "", "equation": "quercetin 4'-O-beta-D-glucoside + H2O = quercetin + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69647", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69647" } ] }, { "id": "69655", "name": "", "equation": "quercetin 3-O-beta-D-glucoside + H2O = quercetin + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69655", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69655" } ] }, { "id": "69659", "name": "", "equation": "kaempferol 3-O-beta-D-glucoside + H2O = kaempferol + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69659", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69659" } ] }, { "id": "69663", "name": "", "equation": "luteolin 7-O-beta-D-glucoside + H2O = luteolin + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69663", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69663" } ] }, { "id": "69667", "name": "", "equation": "luteolin 4'-O-beta-D-glucoside + H2O = luteolin + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69667", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69667" } ] }, { "id": "69671", "name": "", "equation": "(2S)-naringenin 7-O-beta-D-glucoside + H2O = (2S)-naringenin + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69671" } ] }, { "id": "69675", "name": "", "equation": "eriodictyol-7-O-beta-D-glucoside + H2O = (S)-eriodictyol + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69675", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69675" } ] }, { "id": "69679", "name": "", "equation": "apigenin 7-O-beta-D-glucoside + H2O = apigenin + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69679", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69679" } ] }, { "id": "69683", "name": "", "equation": "daidzein 7-O-beta-D-glucoside + H2O = daidzein + beta-D-glucose + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69683" } ] }, { "id": "69687", "name": "", "equation": "genistein 7-O-beta-D-glucoside + H2O = genistein + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69687", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69687" } ] }, { "id": "69699", "name": "", "equation": "beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + H2O = N-hexadecanoylsphing-4-enine + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69699", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69699" } ] }, { "id": "69703", "name": "", "equation": "beta-D-galactosyl-(1<->1')-N-hexadecanoylsphing-4-enine + H2O = beta-D-galactose + N-hexadecanoylsphing-4-enine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69703", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69703" } ] }, { "id": "69707", "name": "", "equation": "beta-D-galactosyl-(1<->1')-N-hexadecanoylsphinganine + H2O = beta-D-galactose + N-hexadecanoylsphinganine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69707", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69707" } ] }, { "id": "69711", "name": "", "equation": "beta-D-glucosyl-(1<->1')-N-hexadecanoylsphinganine + H2O = N-hexadecanoylsphinganine + beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "69711", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69711" } ] }, { "id": "R-BTA-189062", "name": "lactose + H2O => D-glucose + D-galactose", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-188973" ], "output_participant_list": [ "R-ALL-188995" ], "enzyme_list": [ "E1BK89-1" ], "evidence": [ { "id": "R-BTA-189062", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189062" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-188973", "participant_name": "Lac [extracellular region]", "crossref": [ { "id": "17716", "database": "ChEBI", "url": "" }, { "id": "G74621DY", "database": "GlyTouCan", "url": "" }, { "id": "C06373", "database": "COMPOUND", "url": "" }, { "id": "ZINC000004095793", "database": "ZINC", "url": "" }, { "id": "ZINC000004095761", "database": "ZINC", "url": "" }, { "id": "HMDB0035312", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-188995", "participant_name": "Gal [extracellular region]", "crossref": [ { "id": "8143700", "database": "PubChem Substance", "url": "" }, { "id": "ZINC000100008403", "database": "ZINC", "url": "" }, { "id": "17118", "database": "ChEBI", "url": "" }, { "id": "G93924TT", "database": "GlyTouCan", "url": "" }, { "id": "C00124", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BK89", "gene_name": "LCT", "activity": [ { "ec_number": "3.2.1.108", "activity": "lactose + H2O = beta-D-galactose + D-glucose.", "evidence": [ { "id": "E1BK89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ] }, { "ec_number": "3.2.1.62", "activity": "a flavonol 3-O-beta-D-glucoside + H2O = a flavonol + D-glucose.", "evidence": [ { "id": "E1BK89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ] }, { "ec_number": "3.2.1.108", "activity": "", "evidence": [ { "id": "E1BK89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ] }, { "ec_number": "3.2.1.62", "activity": "", "evidence": [ { "id": "E1BK89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK89" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.2.1.108", "ec_name": "lactose + H2O = beta-D-galactose + D-glucose.", "evidence": [ { "id": "3.2.1.108", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.108" }, { "id": "3.2.1.108", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.2.1.108" } ] }, { "ec_number": "3.2.1.62", "ec_name": "a flavonol 3-O-beta-D-glucoside + H2O = a flavonol + D-glucose.", "evidence": [ { "id": "3.2.1.62", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.2.1.62" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], 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"https://www.ensembl.org/id/ENSBTAP00000096248.1" } ] } }, { "isoform_ac": "A0AAA9THG8-1", "url": "https://www.uniprot.org/uniprotkb/E1BEH6/entry#A0AAA9THG8-1", "sequence": { "sequence": "NLLLCSAGPNLKEWLREQFCDHPLEHCEDTRLHDAAYVGDLQTLRSLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGNCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLESAQILLEAGADPNGSRHHRSTPVYHASRVGRADILKALIRYGADVDVNHHLTPDAQPPFSRRLTSLVVCPLYISAAYHNLQCFKLLLQAGANPDFNCNGPVNTQGFYRGSPGCVMDAVLRHGCEAAFVSLLVEFGANLNLVKWESLGPESRGRRKVDPEALQVFKEARSVPRSLLNLCRVAVRRALGKYRLHLIPSLPLPDPIKKFLLYE", "length": 326, "header": "tr|A0AAA9THG8-1|E1BEH6_BOVIN Computationally mapped isoform of Ankyrin repeat and SOCS box protein 1 OS=Bos taurus OX=9913 GN=ASB1 PE=3 SV=1 CANONICAL=E1BEH6-1" }, "locus": { "chromosome": "3", "start_pos": 117735514, "end_pos": 117717463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096008.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096008.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096311.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096311.1" } ] } }, { "isoform_ac": "A0ABI0NNY2-1", "url": "https://www.uniprot.org/uniprotkb/E1BEH6/entry#A0ABI0NNY2-1", "sequence": { "sequence": "MAEGGGRAGPAPAGPNLKEWLREQFCDHPLEHCEDTRLHDAAYVGDLQTLRSLLQEESYRRYGADVDVNHHLTPDAQPPFSRRLTSLVVCPLYISAAYHNLQCFKLLLQAGANPDFNCNGPVNTQGFYRGSPGCVMDAVLRHGCEAAFVSLLVEFGANLNLVKWESLGPESRGRRKVDPEALQVFKEARSVPRSLLNLCRVAVRRALGKYRLHLIPSLPLPDPIKKFLLYE", "length": 231, "header": "tr|A0ABI0NNY2-1|A0ABI0NNY2_BOVIN Computationally mapped isoform of Ankyrin repeat and SOCS box containing 1 OS=Bos taurus OX=9913 GN=ASB1 PE=4 SV=1 CANONICAL=E1BEH6-1" }, "locus": { "chromosome": "3", "start_pos": 117735514, "end_pos": 117716914, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149585.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149585.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107503.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107503.1" } ] } }, { "isoform_ac": "E1BEH6-1", "url": "https://www.uniprot.org/uniprotkb/E1BEH6/entry#E1BEH6-1", "sequence": { "sequence": "MICKLGPAPRRDIFPDSSAPPVDKHSLGGARRGAPPTARPAPRPTPTPQSSSAAARARWASRRERSGSARPQKPLREARARRKPRPRHGHCPRRRKRSRALWLRKWFRPAGSLKRAARGEAAADGLEAEAHGGGRRAGRAGARSAGPNLKEWLREQFCDHPLEHCEDTRLHDAAYVGDLQTLRSLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGNCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLESAQILLEAGADPNGSRHHRSTPVYHASRVGRADILKALIRYGADVDVNHHLTPDAQPPFSRRLTSLVVCPLYISAAYHNLQCFKLLLQAGANPDFNCNGPVNTQGFYRGSPGCVMDAVLRHGCEAAFVSLLVEFGANLNLVKWESLGPESRGRRKVDPEALQVFKEARSVPRSLLNLCRVAVRRALGKYRLHLIPSLPLPDPIKKFLLYE", "length": 464, "header": "tr|E1BEH6-1|E1BEH6_BOVIN Isoform 1 of Ankyrin repeat and SOCS box protein 1 OS=Bos taurus OX=9913 GN=ASB1 PE=3 SV=3 CANONICAL=E1BEH6-1" }, "locus": { "chromosome": "3", "start_pos": 117735514, "end_pos": 117716523, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004378.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004378.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004378.6", "url": "https://www.ensembl.org/id/ENSBTAP00000004378.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 45, "start_aa": "Thr", "end_pos": 45, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr45", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 47, "start_aa": "Thr", "end_pos": 47, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr47", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BEH6", "url": "https://www.uniprot.org/uniprotkb/E1BEH6" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "E1BEH6", "url": "https://www.uniprot.org/uniprotkb/E1BEH6" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BEH6", "url": "https://www.uniprot.org/uniprotkb/E1BEH6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BEH6", "url": "https://www.uniprot.org/uniprotkb/E1BEH6" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179753", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179753", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SK17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SK17-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFE7", "url": "https://www.uniprot.org/uniprotkb/E1BFE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFE7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPEHDDSESQTRPRMPRKRGHMSPKSRHMANSTLLGLLAPPGEAWGVLGQPPSRPNHSPPPSAKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRISLCTHDPAKTCSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 252, "header": "tr|E1BFE7-1|E1BFE7_BOVIN Isoform 1 of Neurexophilin OS=Bos taurus OX=9913 GN=NXPH3 PE=3 SV=3 CANONICAL=E1BFE7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SK17-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE7/entry#A0AAA9SK17-1", "sequence": { "sequence": "MRWNHDTGQNAHPTPSVICGQDDGPPGSEDPEHDDSESQTRPRMPRKRGHMSPKSRHMANSTLLGLLAPPGEAWGVLGQPPSRPNHSPPPSAKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRISLCTHDPAKTCSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 250, "header": "tr|A0AAA9SK17-1|E1BFE7_BOVIN Computationally mapped isoform of Neurexophilin OS=Bos taurus OX=9913 GN=NXPH3 PE=3 SV=1 CANONICAL=E1BFE7-1" }, "locus": { "chromosome": "19", "start_pos": 37039351, "end_pos": 37038447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104779.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104779.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085647.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085647.1" } ] } }, { "isoform_ac": "E1BFE7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE7/entry#E1BFE7-1", "sequence": { "sequence": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPEHDDSESQTRPRMPRKRGHMSPKSRHMANSTLLGLLAPPGEAWGVLGQPPSRPNHSPPPSAKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRISLCTHDPAKTCSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 252, "header": "tr|E1BFE7-1|E1BFE7_BOVIN Isoform 1 of Neurexophilin OS=Bos taurus OX=9913 GN=NXPH3 PE=3 SV=3 CANONICAL=E1BFE7-1" }, "locus": { "chromosome": "19", "start_pos": 37041633, "end_pos": 37038447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020332.5", "url": "https://www.ensembl.org/id/ENSBTAT00000020332.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020332.4", "url": "https://www.ensembl.org/id/ENSBTAP00000020332.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:541093", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541093", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A0H7-1", "protein_name": "Neurexophilin", "gene_name": "NXPH3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHLTRSCIGFLIQGSISLLVVCGQEGPGEGAEQREPESQEGAQAQESGELLPTKPLLTPTLLQNVTLLELVSSSRELWDILDNLSERDHAPHPRGRRDLESASGKLKKIFGWGDFYSNIKTVKLNLLITGKVVDHGNGTVNVFFRHNSTGQGNISVSLVPPTKAVEFDLEQQIFIEAKESKIFNCRVEYEKVDRAKKTTLCTYDPSKTCYHEHTQSHVSWVCSKPFKVICIYITFYSIDYRLVQKVCPDYNYHSDVPYFPSG", "length": 262 }, "evidence": [ { "id": "E1BFE7", "url": "https://omabrowser.org/oma/group/E1BFE7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RTC0-1", "protein_name": "Neurexophilin", "gene_name": "NXPH3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDTEHEDRESQPRPRMPRKRGHISPKSRPVANSPLLGLLAPPGEAWGVLGQPPSRPNHSAPPSAKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRISLCTHDPAKTCSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 252 }, "evidence": [ { "id": "E1BFE7", "url": "https://omabrowser.org/oma/group/E1BFE7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HJP8-1", "protein_name": "Neurexophilin", "gene_name": "Nxph3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPEHDDHEGQPRPRVPRKRGHISPKSRPLANSTLLGLLAPPGEAWGVLGQPPNRPKQSSLPSTKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 252 }, "evidence": [ { "id": "E1BFE7", "url": "https://omabrowser.org/oma/group/E1BFE7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95157-1", "protein_name": "Neurexophilin-3", "gene_name": "NXPH3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPERDDHEGQPRPRVPRKRGHISPKSRPMANSTLLGLLAPPGEAWGILGQPPNRPNHSPPPSAKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFQHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 252 }, "evidence": [ { "id": "E1BFE7", "url": "https://omabrowser.org/oma/group/E1BFE7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91VX5-1", "protein_name": "Neurexophilin-3", "gene_name": "Nxph3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPEHDDHEGQPRPRVPRKRGHISPKSRPLANSTLLGLLAPPGEVWGVLGQPPNRPKQSPLPSTKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 252 }, "evidence": [ { "id": "E1BFE7", "url": "https://omabrowser.org/oma/group/E1BFE7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z2N5-1", "protein_name": "Neurexophilin-3", "gene_name": "Nxph3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQLTRCCFVFLVQGSLYLVICGQEDGPPGSEDPEHDDHEGQPRPRVPRKRGHISPKSRPLANSTLLGLLAPPGEVWGILGQPPNRPKQSPLPSTKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKIVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 252 }, "evidence": [ { "id": "E1BFE7", "url": "https://omabrowser.org/oma/group/E1BFE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BFE7", "url": "https://www.uniprot.org/uniprotkb/E1BFE7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "E1BFE7", "url": 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00131", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00131", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SECLAPW", "url": "https://omabrowser.org/oma/group/SECLAPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45636", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45636", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45636:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45636:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12360", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12360", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SKB4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKB4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKL5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALPGTVPRMVRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEEDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHGFSSYSDSFMNPAAASNHMNPVSNGLSPQVMSILSNPSAVPPQPQADFSISPLHGGLDSATSISASCSQRADPIKPGDSLPTSQSYCPPTYSTTGYSVDPVAGYQYGQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY", "length": 505, "header": "tr|E1BKL5-1|E1BKL5_BOVIN Isoform 1 of Paired box 7 OS=Bos taurus OX=9913 GN=LOC536229 PE=3 SV=1 CANONICAL=E1BKL5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SKB4-1", "url": "https://www.uniprot.org/uniprotkb/E1BKL5/entry#A0AAA9SKB4-1", "sequence": { "sequence": "MEPTRWAPSHRLSASLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEADKKEEDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHGFSSYSDSFMNPAAASNHMNPVSNGLSPQVMSILSNPSAVPPQPQADFSISPLHGGLDSATSISASCSQRADPIKPGDSLPTSQSYCPPTYSTTGYSVDPVAGYQYGQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY", "length": 492, "header": "tr|A0AAA9SKB4-1|E1BKL5_BOVIN Computationally mapped isoform of Paired box 7 OS=Bos taurus OX=9913 GN=LOC536229 PE=3 SV=1 CANONICAL=E1BKL5-1" }, "locus": { "chromosome": "2", "start_pos": 134027484, "end_pos": 133926474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131790.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131790.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085742.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085742.1" } ] } }, { "isoform_ac": "E1BKL5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKL5/entry#E1BKL5-1", "sequence": { "sequence": "MAALPGTVPRMVRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEEDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHGFSSYSDSFMNPAAASNHMNPVSNGLSPQVMSILSNPSAVPPQPQADFSISPLHGGLDSATSISASCSQRADPIKPGDSLPTSQSYCPPTYSTTGYSVDPVAGYQYGQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY", "length": 505, "header": "tr|E1BKL5-1|E1BKL5_BOVIN Isoform 1 of Paired box 7 OS=Bos taurus OX=9913 GN=LOC536229 PE=3 SV=1 CANONICAL=E1BKL5-1" }, "locus": { "chromosome": "2", "start_pos": 134029644, "end_pos": 133926474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019924.4", "url": "https://www.ensembl.org/id/ENSBTAT00000019924.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019924.2", "url": "https://www.ensembl.org/id/ENSBTAP00000019924.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZRA8-1", "protein_name": "Paired box 7", "gene_name": "Pax7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALPGAVPRMMRPGPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEDDEEGDKKEEDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSAYPTTTVSQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADSSSAYGARHSFSSYSDSFMNPGAPSNHMNPVSNGLSPQVMSILSNPSAVPPQPQADFSISPLHGGLDSASSISASCSQRADSIKPGDSLPTSQSYCPPTYSTTGYSVDPVAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY", "length": 505 }, "evidence": [ { "id": "E1BKL5", "url": "https://omabrowser.org/oma/group/E1BKL5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O57418-1", "protein_name": "Paired box protein Pax-7a isoform PAX7C", "gene_name": "pax7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATLPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRGTVPSGEASSVSSISRVLRARFGKKDDDDECDKKDEDGEKKTKHSIDGILGDKGNRTDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPTYQLPESTYPSTTLSQDGSSTLHRPQPLPPSSMHQGGLSADSGSAYGLSSNRHTFSSYSETFMSPTASSNHMNPVSNGLSPQVMSILSNPSAVPSQPQHDFSISPLHGGLEASNPISASCSQRSDPIKSVDSLASTQSYCPPTYSATSYSVDPVTAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGDHSAVLGLLQVETGQAY", "length": 507 }, "evidence": [ { "id": "E1BKL5", "url": "https://omabrowser.org/oma/group/E1BKL5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P23759-3", "protein_name": "Paired box protein Pax-7", "gene_name": "PAX7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY", "length": 505 }, "evidence": [ { "id": "E1BKL5", "url": "https://omabrowser.org/oma/group/E1BKL5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47239-1", "protein_name": "Paired box protein Pax-7", "gene_name": "Pax7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALPGAVPRMMRPGPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEDDEEGDKKEEDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPGAPSNHMNPVSNGLSPQVMSILSNPSAVPPQPQADFSISPLHGGLDSASSISASCSQRADSIKPGDSLPTSQSYCPPTYSTTGYSVDPVAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY", "length": 503 }, "evidence": [ { "id": "E1BKL5", "url": "https://omabrowser.org/oma/group/E1BKL5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "E1BKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "E1BKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" } ], "pmid": "" }, { "name": "skeletal muscle satellite cell differentiation", "id": "GO:0014816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014816", "evidence": [ { "database": "UniProtKB", "id": "E1BKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "E1BKL5", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKL5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 505, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKL5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKL5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 215, "end_pos": 275, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" }, { "id": "PS50803", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50803" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OAR", "eco_id": "ECO_0000259", "start_pos": 479, "end_pos": 491, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKL5" }, { "id": "PS51057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Paired", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 163, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 476, "end_pos": 478 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKE9-1", "uniprot_ac": "E1BKE9", "uniprot_id": "E1BKE9_BOVIN", "mass": { "chemical_mass": 64945.0, "monoisotopic_mass": 64945.0 }, "refseq": { "ac": "NP_001178303", "name": "sentrin-specific protease 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178303" }, "gene_names": [ { "name": "SENP3", "type": "recommended", "evidence": [ { "id": "E1BKE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" } ] }, { "name": "SENP3", "type": "synonym", "evidence": [ { "id": "NP_001178303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178303" } ] } ], "protein_names": [ { "name": "SUMO specific peptidase 3", "type": "synonym", "evidence": [ { "id": "E1BKE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKE9/entry#names_and_taxonomy" } ] }, { "name": "SUMO1/sentrin/SMT3 specific peptidase 3", "type": "synonym", "evidence": [ { "id": "NP_001178303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178303" } ] }, { "name": "sentrin-specific protease 3", "type": "synonym", "evidence": [ { "id": "NP_001178303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178303" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKE9", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SENP3", "url": "https://www.uniprot.org/uniprotkb/E1BKE9", "locus": { "chromosome": "19", "start_pos": 27304661, "end_pos": 27294930, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000131", "url": "https://www.ensembl.org/id/ENSBTAG00000000131" } ] } } ], "crossref": [ { "id": "E1BKE9", "url": "https://alphafold.ebi.ac.uk/entry/E1BKE9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000131", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000131", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100138267", "url": "https://www.ncbi.nlm.nih.gov/gene/100138267", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100138267", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138267", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BKE9", "url": "https://www.orthodb.org/?gene=E1BKE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12606", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12606", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12606:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12606:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178303", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178303", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SKZ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJ40", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJ40-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKE9", "url": "https://www.uniprot.org/uniprotkb/E1BKE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKE9-1", "url": "https://www.uniprot.org/uniprotkb/E1BKE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKETIQGTGSWGPEPPGPGIAPAFSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPTRRLPVPRPSFDASASEEEEEEEDDEDEDEEEEVAAWRLPPRWGQLGASQRPRPPRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRNLAHPKNHLSPREGAVTPQVPSPCCRFDSPRGPPPPRLSLLGALMAEDGVRGSPPVPSGAPMEEDGLRWTPKSPLGPDSGLLSCTLPNGFGGPLGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDVGTAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSAPSRKGLVLQLIQSYQRMPGNAMVRGFRVTYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV", "length": 574, "header": "tr|E1BKE9-1|E1BKE9_BOVIN Isoform 1 of SUMO specific peptidase 3 OS=Bos taurus OX=9913 GN=SENP3 PE=3 SV=3 CANONICAL=E1BKE9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SKZ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BKE9/entry#A0AAA9SKZ0-1", "sequence": { "sequence": "MERLPGAARVQRVCAGASLRGACGLDGPGASTFSGYWKMKETIQGTGSWGPEPPGPGIAPAFSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPTRRLPVPRPSFDASASEEEEEEEDDEDEDEEEEVAAWRLPPRWGQLGASQRPRPPRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRNLAHPKNHLSPREGAVTPQVPSPCCRFDSPRGPPPPRLSLLGALMAEDGVRGSPPVPSGAPMEEDGLRWTPKSPLGPDSGLLSCTLPNGFGGPLGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDVGTAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSAPSRKGLVLQLIQSYQRMPGNAMVRGFRVTYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV", "length": 612, "header": "tr|A0AAA9SKZ0-1|E1BKE9_BOVIN Computationally mapped isoform of SUMO specific peptidase 3 OS=Bos taurus OX=9913 GN=SENP3 PE=3 SV=1 CANONICAL=E1BKE9-1" }, "locus": { "chromosome": "19", "start_pos": 27304225, "end_pos": 27295129, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104170.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104170.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084573.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084573.1" } ] } }, { "isoform_ac": "A0AAA9TJ40-1", "url": "https://www.uniprot.org/uniprotkb/E1BKE9/entry#A0AAA9TJ40-1", "sequence": { "sequence": "MENSLLTLVYGFPAEVVFSRISVPCYWKMKETIQGTGSWGPEPPGPGIAPAFSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPTRRLPVPRPSFDASASEEEEEEEDDEDEDEEEEVAAWRLPPRWGQLGASQRPRPPRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRNLAHPKNHLSPREGAVTPQVPSPCCRFDSPRGPPPPRLSLLGALMAEDGVRGSPPVPSGAPMEEDGLRWTPKSPLGPDSGLLSCTLPNGFGGPLGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDVGTAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSAPSRKGLVLQLIQSYQRMPGNAMVRGFRVTYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV", "length": 602, "header": "tr|A0AAA9TJ40-1|E1BKE9_BOVIN Computationally mapped isoform of SUMO specific peptidase 3 OS=Bos taurus OX=9913 GN=SENP3 PE=3 SV=1 CANONICAL=E1BKE9-1" }, "locus": { "chromosome": "19", "start_pos": 27304225, "end_pos": 27295952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101403.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101403.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098464.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098464.1" } ] } }, { "isoform_ac": "E1BKE9-1", "url": "https://www.uniprot.org/uniprotkb/E1BKE9/entry#E1BKE9-1", "sequence": { "sequence": "MKETIQGTGSWGPEPPGPGIAPAFSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPTRRLPVPRPSFDASASEEEEEEEDDEDEDEEEEVAAWRLPPRWGQLGASQRPRPPRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRNLAHPKNHLSPREGAVTPQVPSPCCRFDSPRGPPPPRLSLLGALMAEDGVRGSPPVPSGAPMEEDGLRWTPKSPLGPDSGLLSCTLPNGFGGPLGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDVGTAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSAPSRKGLVLQLIQSYQRMPGNAMVRGFRVTYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV", "length": 574, "header": "tr|E1BKE9-1|E1BKE9_BOVIN Isoform 1 of SUMO specific peptidase 3 OS=Bos taurus OX=9913 GN=SENP3 PE=3 SV=3 CANONICAL=E1BKE9-1" }, "locus": { "chromosome": "19", "start_pos": 27304225, "end_pos": 27296719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000143.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000143.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000143.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000143.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100138267", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138267", "resource": "KEGG Pathway" }, { "id": "R-BTA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "deSUMOylase activity", "id": "GO:0016929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016929", "evidence": [ { "database": "UniProtKB", "id": "E1BKE9", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "E1BKE9", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" } ], "pmid": "" }, { "name": "cysteine-type peptidase activity", "id": "GO:0008234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008234", "evidence": [ { "database": "UniProtKB", "id": "E1BKE9", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "E1BKE9", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BKE9", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" } ], "pmid": "" }, { "name": "protein desumoylation", "id": "GO:0016926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016926", "evidence": [ { "database": "UniProtKB", "id": "E1BKE9", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1BKE9", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" } ], "pmid": "" }, { "name": "MLL1 complex", "id": "GO:0071339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071339", "evidence": [ { "database": "UniProtKB", "id": "E1BKE9", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BKE9", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKE9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 574, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKE9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKE9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKE9" }, { "id": "PS50600", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50600" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like protease family profile", "eco_id": "ECO_0000259", "start_pos": 386, "end_pos": 543, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 528, "end_pos": 530 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK06-1", "uniprot_ac": "E1BK06", "uniprot_id": "E1BK06_BOVIN", "mass": { "chemical_mass": 48408.0, "monoisotopic_mass": 48408.0 }, "refseq": { "ac": "NP_001179589", "name": "mast cell carboxypeptidase A precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179589" }, "gene_names": [ { "name": "CPA3", "type": "recommended", "evidence": [ { "id": "E1BK06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK06" } ] }, { "name": "CPA3", "type": "synonym", "evidence": [ { "id": "NP_001179589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179589" } ] } ], "protein_names": [ { "name": "Carboxypeptidase B", "type": "recommended", "evidence": [ { "id": "E1BK06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK06/entry#names_and_taxonomy" } ] }, { "name": "3.4.17.2", "type": "synonym", "evidence": [ { "id": "E1BK06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK06/entry#names_and_taxonomy" } ] }, { "name": "carboxypeptidase A3 (mast cell)", "type": "synonym", "evidence": [ { "id": "NP_001179589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179589" } ] }, { "name": "mast cell carboxypeptidase A precursor", "type": "synonym", "evidence": [ { "id": "NP_001179589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179589" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK06", "url": "https://www.uniprot.org/uniprotkb/E1BK06" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CPA3", "url": "https://www.uniprot.org/uniprotkb/E1BK06", "locus": { "chromosome": "1", "start_pos": 119297395, "end_pos": 119329553, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015008", "url": "https://www.ensembl.org/id/ENSBTAG00000015008" } ] } } ], "crossref": [ { "id": "E1BK06", "url": "https://alphafold.ebi.ac.uk/entry/E1BK06", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015008", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015008", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "528454", "url": "https://www.ncbi.nlm.nih.gov/gene/528454", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:528454", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528454", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PPNHKDL", "url": "https://omabrowser.org/oma/group/PPNHKDL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BK06", "url": "https://www.orthodb.org/?gene=E1BK06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022377", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179589", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179589", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SL31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SL31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SL31-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SL31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYE2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK06", "url": "https://www.uniprot.org/uniprotkb/E1BK06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK06-1", "url": "https://www.uniprot.org/uniprotkb/E1BK06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFLLPVGLIATTLAIAPVRFDGDKVLRVKLQDEKQANIIKDLAKTSQLDFWYPDATHHVAANMTVDFQISAKESQFVQSALDQNQMHYEILIHDVQEEVEKQFDVKEDNPGRHSYAKYNNWNKIVAWTEKMVHKHPKMVSRIKIGTTVEDNPLYVLKIAGKDKRRKAIFMDCGIHAREWISPAFCQWFVYQATKTYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTQNRMWRKNRSRNQNSKCIGTDLNRNFNVSWNSFPNTNDPCQEIYRGPAPESEKETKAVSDFIRSHLKSIKAYITFHSYSQMLLFPYGYTSELPPNHKNLAKVAKIATDVLSTPYETHYTYGPIASTIYPTSGSSLDWAYNLGIKHTFAFELRDKGRFGFLLPESQIKPTCKETMLALKFIVKYILKHTS", "length": 417, "header": "tr|E1BK06-1|E1BK06_BOVIN Isoform 1 of Carboxypeptidase B OS=Bos taurus OX=9913 GN=CPA3 PE=3 SV=2 CANONICAL=E1BK06-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SL31-1", "url": "https://www.uniprot.org/uniprotkb/E1BK06/entry#A0AAA9SL31-1", "sequence": { "sequence": "MRFLLPVGLIATTLAIAPVRFDGDKVLRVKLQDEKQANIIKDLAKTSQLDFWYPDATHHVAANMTVDFQISAKESQFVQSALDQNQMHYEILIHDVQEEVEKQFDVKEDNPGRHSYAKYNNWNKIVAWTEKMVHKHPKMVSRIKIGTTVEDNPLYVLKIRTMVLPERNKCACSDSRNRRQIAGKDKRRKAIFMDCGIHAREWISPAFCQWFVYQATKTYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTQNRMWRKNRSRNQNSKCIGTDLNRNFNVSWNSFPNTNDPCQEIYRGPAPESEKETKAVSDFIRSHLKSIKAYITFHSYSQMLLFPYGYTSELPPNHKNLAKVAKIATDVLSTPYETHYTYGPIASTIYPTSGSSLDWAYNLGIKHTFAFELRDKGRFGFLLPESQIKPTCKETMLALKFIVKYILKHTS", "length": 439, "header": "tr|A0AAA9SL31-1|E1BK06_BOVIN Computationally mapped isoform of Carboxypeptidase B OS=Bos taurus OX=9913 GN=CPA3 PE=3 SV=1 CANONICAL=E1BK06-1" }, "locus": { "chromosome": "1", "start_pos": 119329524, "end_pos": 119297772, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087674.1", "url": "https://www.ensembl.org/id/ENSBTAT00000087674.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084587.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084587.1" } ] } }, { "isoform_ac": "A0AAA9SYE2-1", "url": "https://www.uniprot.org/uniprotkb/E1BK06/entry#A0AAA9SYE2-1", "sequence": { "sequence": "MRFLLPVGLIATTLAIAPVRFDGDKVLRVKLQDEKQANIIKDLAKTSQLDFWYPDATHHVAANMTVDFQISAKESQFVQSALDQNQMHYEILIHDVQEEVEKQFDVKEDNPGRHSYAKYNNWNKIVAWTEKMVHKHPKMVSRIKIGTTVEDNPLYVLKATKTYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTQNRMWRKNRSRNQNSKCIGTDLNRNFNVSWNSFPNTNDPCQEIYRGPAPESEKETKAVSDFIRSHLKSIKAYITFHSYSQMLLFPYGYTSELPPNHKNLAKVAKIATDVLSTPYETHYTYGPIASTIYPTSGSSLDWAYNLGIKHTFAFELRDKGRFGFLLPESQIKPTCKETMLALKFIVKYILKHTS", "length": 383, "header": "tr|A0AAA9SYE2-1|E1BK06_BOVIN Computationally mapped isoform of Carboxypeptidase B OS=Bos taurus OX=9913 GN=CPA3 PE=3 SV=1 CANONICAL=E1BK06-1" }, "locus": { "chromosome": "1", "start_pos": 119329524, "end_pos": 119297772, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134694.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134694.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089276.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089276.1" } ] } }, { "isoform_ac": "E1BK06-1", "url": "https://www.uniprot.org/uniprotkb/E1BK06/entry#E1BK06-1", "sequence": { "sequence": "MRFLLPVGLIATTLAIAPVRFDGDKVLRVKLQDEKQANIIKDLAKTSQLDFWYPDATHHVAANMTVDFQISAKESQFVQSALDQNQMHYEILIHDVQEEVEKQFDVKEDNPGRHSYAKYNNWNKIVAWTEKMVHKHPKMVSRIKIGTTVEDNPLYVLKIAGKDKRRKAIFMDCGIHAREWISPAFCQWFVYQATKTYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTQNRMWRKNRSRNQNSKCIGTDLNRNFNVSWNSFPNTNDPCQEIYRGPAPESEKETKAVSDFIRSHLKSIKAYITFHSYSQMLLFPYGYTSELPPNHKNLAKVAKIATDVLSTPYETHYTYGPIASTIYPTSGSSLDWAYNLGIKHTFAFELRDKGRFGFLLPESQIKPTCKETMLALKFIVKYILKHTS", "length": 417, "header": "tr|E1BK06-1|E1BK06_BOVIN Isoform 1 of Carboxypeptidase B OS=Bos taurus OX=9913 GN=CPA3 PE=3 SV=2 CANONICAL=E1BK06-1" }, "locus": { "chromosome": "1", "start_pos": 119329524, "end_pos": 119297772, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019982.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019982.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019982.5", "url": "https://www.ensembl.org/id/ENSBTAP00000019982.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 358, "start_aa": "Thr", "end_pos": 358, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr358", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:528454", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528454", "resource": "KEGG Pathway" }, { "id": "R-BTA-2022377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022377", "resource": "Reactome", "description": "Metabolism of Angiotensinogen to Angiotensins" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I0U3-1", "protein_name": "Mast cell carboxypeptidase A", "gene_name": "Cpa3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKFFLLTVVVSTTLATAPVRFDREKIFRVTPVDEKEARVLKDLAQIIELDFWYPDATHDVAANMTVDFRVSEKESQTIQSTLEQHKMNYEILIHDLQEEIEKQFDVKDEVSGRHSYGKYNDWDKIVSWTEKMVAKHPEMVSRIKIGSTVEDNPLYVLKVGRKGKERKAIFIDCGIHAREWVSPAFCQWFVYQATKSYGKNRIMTKLLDRMTFYVLPVVNVDGYIWSWTQNRMWRKNRSKNQNSTCIGTDLNRNFDVSWDSSPNTNDPCQEVYRGPAPESEKETKAVTNFIRSHLNSIKAYITFHSYSQMLLFPYGYTSKLPPNHSDLLKVARIATDFLSSRYETHYIYGPIASTIYPTSGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCKETMLSVKFIAKYILKNTS", "length": 417 }, "evidence": [ { "id": "E1BK06", "url": "https://omabrowser.org/oma/group/E1BK06/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P15088-1", "protein_name": "Mast cell carboxypeptidase A", "gene_name": "CPA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKHTS", "length": 417 }, "evidence": [ { "id": "E1BK06", "url": "https://omabrowser.org/oma/group/E1BK06/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15089-1", "protein_name": "Mast cell carboxypeptidase A", "gene_name": "Cpa3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFFLLMAVIYTTLAIAPVHFDREKVFRVKLQNEKHASVLKNLTQSIELDFWYPDAIHDIAVNMTVDFRVSEKESQTIQSTLEQHKIHYEILIHDLQEEIEKQFDVKDEIAGRHSYAKYNDWDKIVSWTEKMLEKHPEMVSRIKIGSTVEDNPLYVLKIGKKDGERKAIFMDCGIHAREWISPAFCQWFVYQATKSYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTQDRMWRKNRSRNQNSTCIGTDLNRNFDVSWDSSPNTNKPCLNVYRGPAPESEKETKAVTNFIRSHLNSIKAYITFHSYSQMLLIPYGYTFKLPPNHQDLLKVARIATDALSTRYETRYIYGPIASTIYKTSGSSLDWVYDLGIKHTFAFELRDKGKSGFLLPESRIKPTCKETMLSVKFIAKYILKNTS", "length": 417 }, "evidence": [ { "id": "E1BK06", "url": "https://omabrowser.org/oma/group/E1BK06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P21961-1", "protein_name": "Mast cell carboxypeptidase A", "gene_name": "Cpa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LMGVIYSTLAIAPVQFDREKVFRVKLQDEKQASILKNLTQTIELDFWYPDAIHDIAVNMTVDFRVTEKESQTIQSTLEQHKMDYEILINDLQEEIDKQFDVKEEIAGRHSYAKYNDWNKIVSWTEKMVEKHPEMVSRIKIGSTVEDNPLYVLKIGRKDGERKAIFMDCGIHAREWVSPAFCQWFVYQAAKSYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTKDRMWRKNRSKNPNSTCIGTDLNRNFDVSWDSSPNTDNPCLSVYRGPAPESEKETKAVTNFIRSHLNSIKAYITFHSYSQMLLFPYGYTIKLPPNHQDLLKVARIATDVLSSRYETRYIYGPIASTIYKTSGSSLDWAYDLGIKHTFAFELRDKGKSGFLLPESRIKPTCKETMLSVKFIAKYILKHTS", "length": 412 }, "evidence": [ { "id": "E1BK06", "url": "https://omabrowser.org/oma/group/E1BK06/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0E9F9-1", "protein_name": "Zinc carboxypeptidase A 1", "gene_name": "Dmel\\CG2915", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGNKIINMPAARIGTQWLVILCVAMAASGTNLDSGICPVAGDSGCRGNPPDQARYDNYRIYNVEFENQEQIELFQKLEEQSDSLTFIGHAREVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEKIDRNLAEVQPESIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKLTSNANNKAIFIESGIHAREWISPAAATYIINQLLTSQDPKVQQLAQDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQLFGTCRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAAIKAENGRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPTASEAFTAIRAIVEAAAEKGYYK", "length": 453 }, "evidence": [ { "id": "E1BK06", "url": "https://omabrowser.org/oma/group/E1BK06/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BK06", "url": "https://www.uniprot.org/uniprotkb/E1BK06" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BK06", "url": "https://www.uniprot.org/uniprotkb/E1BK06" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BK06", "url": "https://www.uniprot.org/uniprotkb/E1BK06" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "E1BK06", "url": "https://www.uniprot.org/uniprotkb/E1BK06" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "angiotensin maturation", "id": "GO:0002003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002003", "evidence": [ { "database": "UniProtKB", "id": "E1BK06", "url": "https://www.uniprot.org/uniprotkb/E1BK06" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BK06", "url": "https://www.uniprot.org/uniprotkb/E1BK06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-2028294", "name": "Mast Cell Carboxypeptidase hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-33) (Angiotensin-(1-9))", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P00732-1", "Q2KIG3-1", "E1BK06-1" ], "evidence": [ { "id": "R-BTA-2028294", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2028294" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BK06", "gene_name": "CPA3", "activity": [ { "ec_number": "3.4.17.2", "activity": "Preferential release of a C-terminal lysine or arginine amino acid.", "evidence": [ { "id": "E1BK06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK06" } ] }, { "ec_number": "3.4.17.2", "activity": "", "evidence": [ { "id": "E1BK06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK06" } ] } ] }, { "uniprot_ac": "P00732", "gene_name": "CPB1", "activity": [ { "ec_number": "3.4.17.2", "activity": "Preferential release of a C-terminal lysine or arginine amino acid.", "evidence": [ { "id": "P00732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00732" } ] }, { "ec_number": "3.4.17.2", "activity": "", "evidence": [ { "id": "P00732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00732" } ] } ] }, { "uniprot_ac": "Q2KIG3", "gene_name": "CPB2", "activity": [ { "ec_number": "3.4.17.20", "activity": "Release of C-terminal Arg and Lys from a polypeptide.", "evidence": [ { "id": "Q2KIG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIG3" } ] }, { "ec_number": "3.4.17.20", "activity": "", "evidence": [ { "id": "Q2KIG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIG3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BK06-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 417, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BK06-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BK06" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BK06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK06" }, { "id": "PS52035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M14", "eco_id": "ECO_0000259", "start_pos": 118, "end_pos": 412, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.17.2", "ec_name": "Preferential release of a C-terminal lysine or arginine amino acid.", "evidence": [ { "id": "3.4.17.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.17.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 358 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKC5-1", "uniprot_ac": "E1BKC5", "uniprot_id": "E1BKC5_BOVIN", "mass": { "chemical_mass": 28518.0, "monoisotopic_mass": 28518.0 }, "refseq": { "ac": "NP_001180118", "name": "kallikrein-8 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180118" }, "gene_names": [ { "name": "KLK8", "type": "recommended", "evidence": [ { "id": "E1BKC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ] }, { "name": "KLK8", "type": "synonym", "evidence": [ { "id": "NP_001180118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180118" } ] }, { "name": "KLNH", "type": "synonym", "evidence": [ { "id": "NP_001180118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180118" } ] } ], "protein_names": [ { "name": "tissue kallikrein", "type": "recommended", "evidence": [ { "id": "E1BKC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKC5/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.35", "type": "synonym", "evidence": [ { "id": "E1BKC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKC5/entry#names_and_taxonomy" } ] }, { "name": "kallikrein 8 (neuropsin/ovasin)", "type": "synonym", "evidence": [ { "id": "NP_001180118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180118" } ] }, { "name": "kallikrein H", "type": "synonym", "evidence": [ { "id": "NP_001180118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180118" } ] }, { "name": "kallikrein-8 precursor", "type": "synonym", "evidence": [ { "id": "NP_001180118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180118" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KLK8", "url": "https://www.uniprot.org/uniprotkb/E1BKC5", "locus": { "chromosome": "18", "start_pos": 56971922, "end_pos": 56978107, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015128", "url": "https://www.ensembl.org/id/ENSBTAG00000015128" } ] } } ], "crossref": [ { "id": "E1BKC5", "url": "https://alphafold.ebi.ac.uk/entry/E1BKC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015128", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015128", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "618438", "url": "https://www.ncbi.nlm.nih.gov/gene/618438", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618438", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618438", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GMTCYSG", "url": "https://omabrowser.org/oma/group/GMTCYSG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKC5", "url": "https://www.orthodb.org/?gene=E1BKC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001180118", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180118", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SQ66", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQ66-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKC5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRPSPAAVWIWMLLLLLLESQAGHVRAQENKVLEGKECKPHSQPWQTALFQGVRLICGGVLIEDNWVLTAAHCQKKKYVVRMGEHSLKKKDESEQERAVARSIPHPCYNNSKNDHSYDMMLIQLRGRVSLGPKVKPIKLADHCPQVGQKCTISGWGTVTSPREKFPDTLNCAEVKIIPQDQCEKAYPGQVTDSMVCASDSSGADTCQGDSGGPLVCNGVLHGITSWGSDPCGRPEKPGVYSKVCRSLDWIKKTIGRRG", "length": 259, "header": "tr|E1BKC5-1|E1BKC5_BOVIN Isoform 1 of tissue kallikrein OS=Bos taurus OX=9913 GN=KLK8 PE=3 SV=1 CANONICAL=E1BKC5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SQ66-1", "url": "https://www.uniprot.org/uniprotkb/E1BKC5/entry#A0AAA9SQ66-1", "sequence": { "sequence": "MGRPSPAAVWIWMLLLLLLESQAEKFPDTLNCAEVKIIPQDQCEKAYPGQVTDSMVCASDSSGADTCQGDSGGPLVCNGVLHGITSWGSDPCGRPEKPGVYSKVCRSLDWIKKTIGRRG", "length": 119, "header": "tr|A0AAA9SQ66-1|E1BKC5_BOVIN Computationally mapped isoform of tissue kallikrein OS=Bos taurus OX=9913 GN=KLK8 PE=3 SV=1 CANONICAL=E1BKC5-1" }, "locus": { "chromosome": "18", "start_pos": 56977491, "end_pos": 56972312, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110197.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110197.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088470.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088470.1" } ] } }, { "isoform_ac": "E1BKC5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKC5/entry#E1BKC5-1", "sequence": { "sequence": "MGRPSPAAVWIWMLLLLLLESQAGHVRAQENKVLEGKECKPHSQPWQTALFQGVRLICGGVLIEDNWVLTAAHCQKKKYVVRMGEHSLKKKDESEQERAVARSIPHPCYNNSKNDHSYDMMLIQLRGRVSLGPKVKPIKLADHCPQVGQKCTISGWGTVTSPREKFPDTLNCAEVKIIPQDQCEKAYPGQVTDSMVCASDSSGADTCQGDSGGPLVCNGVLHGITSWGSDPCGRPEKPGVYSKVCRSLDWIKKTIGRRG", "length": 259, "header": "tr|E1BKC5-1|E1BKC5_BOVIN Isoform 1 of tissue kallikrein OS=Bos taurus OX=9913 GN=KLK8 PE=3 SV=1 CANONICAL=E1BKC5-1" }, "locus": { "chromosome": "18", "start_pos": 56977491, "end_pos": 56972312, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020127.5", "url": "https://www.ensembl.org/id/ENSBTAT00000020127.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020127.3", "url": "https://www.ensembl.org/id/ENSBTAP00000020127.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:618438", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618438", "resource": "KEGG Pathway" }, { "id": "R-BTA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X3Y4-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "LOC101750376", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "PQIFPFSPHIRTNNPNSSPFSPRICINNPNSSPFYPIFFESIPQIFPFSPHIRTNNPNSSPFHPIFAPITPILPTFAPFSPQITPTLPSPPPPAPPPFTLSSHLSVRLGGRGGRDPPVTEQRRLSSKAIPYPRYDAATKDGDLMLIKLLQPARLHQHVRPLPLASSCPVPGMTCQISGWGSTTSPEVTFPEDLRCAKVTIVPEERCRRIYPGSVTANMVCAGEHRNRADSCQGDSGGPLVCDGRLQGIVSWGPGVCGDPQKPGVYVNLCKYTRWIHDTMRRN", "length": 282 }, "evidence": [ { "id": "E1BKC5", "url": "https://omabrowser.org/oma/group/E1BKC5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3I4R6-1", "protein_name": "Kallikrein-8", "gene_name": "LOC100752953", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGRPPPCAIQKWIFLFLLMGTWAGLTKAQGSKVLEGQECKPHSQPWQTALFQGPRLVCGGVLVGDKWILTAAHCKKQKYSVRLGDHSLQSRDKPEQEIQVAQSIQHPCYNSSNPEDHSHDVMLIRMRHSANIGDKVKSIKLAEECPKVGQKCTISGWGTVTSPRENFPDTLNCAEVEIFSQSKCEKAYPGKVTEGMVCAGSSNGADTCQGDSGGPLVCNGVLQGITSWGSDPCGKPEKPGVYTNICYYSDWIHKTMNNRD", "length": 260 }, "evidence": [ { "id": "E1BKC5", "url": "https://omabrowser.org/oma/group/E1BKC5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60259-1", "protein_name": "Kallikrein-8", "gene_name": "KLK8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRPRPRAAKTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG", "length": 260 }, "evidence": [ { "id": "E1BKC5", "url": "https://omabrowser.org/oma/group/E1BKC5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88780-1", "protein_name": "Kallikrein-8", "gene_name": "Klk8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRPPPCAIQTWILLFLLMGAWAGLTRAQGSKILEGQECKPHSQPWQTALFQGERLVCGGVLVGDRWVLTAAHCKKDKYSVRLGDHSLQKRDEPEQEIQVARSIQHPCFNSSNPEDHSHDIMLIRLQNSANLGDKVKPIELANLCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNGADTCQGDSGGPLVCNGVLQGITTWGSDPCGKPEKPGVYTKICRYTNWIKKTMGKRD", "length": 260 }, "evidence": [ { "id": "E1BKC5", "url": "https://omabrowser.org/oma/group/E1BKC5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61955-1", "protein_name": "Kallikrein-8", "gene_name": "Klk8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRPPPCAIQPWILLLLFMGAWAGLTRAQGSKILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNGADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTMDNRD", "length": 260 }, "evidence": [ { "id": "E1BKC5", "url": "https://omabrowser.org/oma/group/E1BKC5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "pmid": "" }, { "name": "regulation of synapse organization", "id": "GO:0050807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050807", "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "pmid": "" }, { "name": "keratinocyte proliferation", "id": "GO:0043616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043616", "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "pmid": "" }, { "name": "serine protease inhibitor complex", "id": "GO:0097180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097180", "evidence": [ { "database": "UniProtKB", "id": "E1BKC5", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-8850831", "name": "KLK5 cleaves and activates KLK8", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-BTA-8850832" ], "output_participant_list": [ "R-BTA-8850829", "R-BTA-8850833" ], "enzyme_list": [ "E1BGD9-1", "E1BKC5-1" ], "evidence": [ { "id": "R-BTA-8850831", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8850831" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-8850829", "participant_name": "KLK8 [extracellular region]", "crossref": [ { "id": "ENSBTAT00000020127", "database": "ENSEMBL", "url": "" }, { "id": "NP_001180118.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAG00000015128", "database": "ENSEMBL", "url": "" }, { "id": "30682", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000020127", "database": "ENSEMBL", "url": "" }, { "id": "E1BKC5", "database": "UniProt", "url": "" }, { "id": "XP_010813403.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-BTA-8850832", "participant_name": "KLK8 [extracellular region]", "crossref": [ { "id": "E1BKC5", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000015128", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000020127", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000020127", "database": "ENSEMBL", "url": "" }, { "id": "XP_010813403.1", "database": "RefSeq", "url": "" }, { "id": "NP_001180118.1", "database": "RefSeq", "url": "" }, { "id": "30682", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-8850833", "participant_name": "KLK8 [extracellular region]", "crossref": [ { "id": "NP_001180118.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAG00000015128", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000020127", "database": "ENSEMBL", "url": "" }, { "id": "30682", "database": "VGNC", "url": "" }, { "id": "XP_010813403.1", "database": "RefSeq", "url": "" }, { "id": "E1BKC5", "database": "UniProt", "url": "" }, { "id": "ENSBTAP00000020127", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BGD9", "gene_name": "KLK5", "activity": [ { "ec_number": "3.4.21.35", "activity": "Preferential cleavage of Arg-|-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa.", "evidence": [ { "id": "E1BGD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ] }, { "ec_number": "3.4.21.35", "activity": "", "evidence": [ { "id": "E1BGD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ] } ] }, { "uniprot_ac": "E1BKC5", "gene_name": "KLK8", "activity": [ { "ec_number": "3.4.21.35", "activity": "Preferential cleavage of Arg-|-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa.", "evidence": [ { "id": "E1BKC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ] }, { "ec_number": "3.4.21.35", "activity": "", "evidence": [ { "id": "E1BKC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKC5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 259, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKC5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKC5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 256, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.21.35", "ec_name": "Preferential cleavage of Arg-|-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa.", "evidence": [ { "id": "3.4.21.35", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.21.35" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BL77-1", "uniprot_ac": "E1BL77", "uniprot_id": "E1BL77_BOVIN", "mass": { "chemical_mass": 32360.0, "monoisotopic_mass": 32360.0 }, "refseq": { "ac": "XP_002688979", "name": "transmembrane and immunoglobulin domain-containing protein 2", "summary": "", "url": 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taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BL77", "url": "https://www.uniprot.org/uniprotkb/E1BL77" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMIGD2", "url": "https://www.uniprot.org/uniprotkb/E1BL77", "locus": { "chromosome": "7", "start_pos": 19782735, "end_pos": 19775122, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004936", "url": "https://www.ensembl.org/id/ENSBTAG00000004936" } ] } } ], "crossref": [ { "id": "E1BL77", "url": "https://alphafold.ebi.ac.uk/entry/E1BL77", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004936", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004936", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "524354", "url": "https://www.ncbi.nlm.nih.gov/gene/524354", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524354", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524354", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SWQPPGN", "url": "https://omabrowser.org/oma/group/SWQPPGN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BL77", "url": "https://www.orthodb.org/?gene=E1BL77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14334:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14334:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002688979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688979", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SQV9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQV9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL77", "url": "https://www.uniprot.org/uniprotkb/E1BL77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL77-1", "url": "https://www.uniprot.org/uniprotkb/E1BL77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSPGTVLVLLVQFWVLQGVTGLTVQQAPKLLQVRQDSQVTLACQVMHAQAWEWLRVEWIKDADIFCQTHIINGSLSKDVCGPQGWLSWQPPGNLTLQLNHVSLNDSGLYVCGATVEIPVWEEAQGNGTQLLVERGVWLQDHSFSGLYFAPLVTGAVAVAVFALGAGIWGRRRCRNGDAGSPIYSNVLYRPRRAARKKAWPVERKVLDSEDQKGQSFYSISFPQRPKSHMAPKFCPSPRPIHPISAVRISPGPGSSGQPRSRGFLEVGREIRTAGEPEKTYPQRLYKDVTYS", "length": 292, "header": "tr|E1BL77-1|E1BL77_BOVIN Isoform 1 of Transmembrane and immunoglobulin domain containing 2 OS=Bos taurus OX=9913 GN=TMIGD2 PE=4 SV=3 CANONICAL=E1BL77-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SQV9-1", "url": "https://www.uniprot.org/uniprotkb/E1BL77/entry#A0AAA9SQV9-1", "sequence": { "sequence": "MGSPGTVLVLLVQFWVLQGVTGLTVQQAPKLLQVRQDSQVTLACQVMHAQAWEWLRVEWIKDADIFCQTHIINGSLSKDVCGPQGWLSWQPPGNLTLQLNHVSLNDSGLYVCGATVEIPVWEEAQGNGTQLLVERGLYFAPLVTGAVAVAVFALGAGIWGRRRCRNGDAGSPIYSNVLYRPRRAARKKAWPVERKVLDSEDQKGQSFYSISFPQRPKSHMAPKFCPSPRPIHPISAVRISPGPGSSGQPRSRGFLEVGREIRTAGEPEKTYPQRLYKDVTYS", "length": 282, "header": "tr|A0AAA9SQV9-1|E1BL77_BOVIN Computationally mapped isoform of Transmembrane and immunoglobulin domain containing 2 OS=Bos taurus OX=9913 GN=TMIGD2 PE=4 SV=1 CANONICAL=E1BL77-1" }, "locus": { "chromosome": "7", "start_pos": 19782405, "end_pos": 19775184, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093376.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093376.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088722.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088722.1" } ] } }, { "isoform_ac": "E1BL77-1", "url": "https://www.uniprot.org/uniprotkb/E1BL77/entry#E1BL77-1", "sequence": { "sequence": "MGSPGTVLVLLVQFWVLQGVTGLTVQQAPKLLQVRQDSQVTLACQVMHAQAWEWLRVEWIKDADIFCQTHIINGSLSKDVCGPQGWLSWQPPGNLTLQLNHVSLNDSGLYVCGATVEIPVWEEAQGNGTQLLVERGVWLQDHSFSGLYFAPLVTGAVAVAVFALGAGIWGRRRCRNGDAGSPIYSNVLYRPRRAARKKAWPVERKVLDSEDQKGQSFYSISFPQRPKSHMAPKFCPSPRPIHPISAVRISPGPGSSGQPRSRGFLEVGREIRTAGEPEKTYPQRLYKDVTYS", "length": 292, "header": "tr|E1BL77-1|E1BL77_BOVIN Isoform 1 of Transmembrane and immunoglobulin domain containing 2 OS=Bos taurus OX=9913 GN=TMIGD2 PE=4 SV=3 CANONICAL=E1BL77-1" }, "locus": { "chromosome": "7", "start_pos": 19782405, "end_pos": 19775184, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044822.5", "url": "https://www.ensembl.org/id/ENSBTAT00000044822.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042277.4", "url": "https://www.ensembl.org/id/ENSBTAP00000042277.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:524354", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524354", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q96BF3-1", "protein_name": "Transmembrane and immunoglobulin domain-containing protein 2", "gene_name": "TMIGD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSPGMVLGLLVQIWALQEASSLSVQQGPNLLQVRQGSQATLVCQVDQATAWERLRVKWTKDGAILCQPYITNGSLSLGVCGPQGRLSWQAPSHLTLQLDPVSLNHSGAYVCWAAVEIPELEEAEGNITRLFVDPDDPTQNRNRIASFPGFLFVLLGVGSMGVAAIVWGAWFWGRRSCQQRDSGNSPGNAFYSNVLYRPRGAPKKSEDCSGEGKDQRGQSIYSTSFPQPAPRQPHLASRPCPSPRPCPSPRPGHPVSMVRVSPRPSPTQQPRPKGFPKVGEE", "length": 282 }, "evidence": [ { "id": "E1BL77", "url": "https://omabrowser.org/oma/group/E1BL77/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "coreceptor activity", "id": "GO:0015026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026", "evidence": [ { "database": "UniProtKB", "id": "E1BL77", "url": "https://www.uniprot.org/uniprotkb/E1BL77" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "E1BL77", "url": "https://www.uniprot.org/uniprotkb/E1BL77" } ], "pmid": "" }, { "name": "B cell receptor complex", "id": "GO:0019815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019815", "evidence": [ { "database": "UniProtKB", "id": "E1BL77", "url": "https://www.uniprot.org/uniprotkb/E1BL77" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "T cell costimulation", "id": "GO:0031295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031295", "evidence": [ { "database": "UniProtKB", "id": "E1BL77", "url": "https://www.uniprot.org/uniprotkb/E1BL77" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "E1BL77", "url": "https://www.uniprot.org/uniprotkb/E1BL77" } ], "pmid": "" }, { "name": "positive regulation of cytokine production", "id": "GO:0001819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001819", "evidence": [ { "database": "UniProtKB", "id": "E1BL77", "url": "https://www.uniprot.org/uniprotkb/E1BL77" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "E1BL77", "url": "https://www.uniprot.org/uniprotkb/E1BL77" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "E1BL77", "url": "https://www.uniprot.org/uniprotkb/E1BL77" } ], "pmid": "" }, { "name": "positive regulation of activated T cell proliferation", "id": "GO:0042104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042104", "evidence": [ { "database": "UniProtKB", "id": "E1BL77", "url": "https://www.uniprot.org/uniprotkb/E1BL77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BL77-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 292, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BL77-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BL77" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL77" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 115, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 127, "end_pos": 129 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BL89-1", "uniprot_ac": "E1BL89", "uniprot_id": "E1BL89_BOVIN", "mass": { "chemical_mass": 30062.0, "monoisotopic_mass": 30062.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM192", "type": "recommended", "evidence": [ { "id": "E1BL89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL89" } ] } ], "protein_names": [ { "name": "Transmembrane protein 192", "type": "recommended", "evidence": [ { "id": "E1BL89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL89/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BL89", "url": "https://www.uniprot.org/uniprotkb/E1BL89" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM192", "url": "https://www.uniprot.org/uniprotkb/E1BL89", "locus": { "chromosome": "17", "start_pos": 180812, "end_pos": 210033, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000035265", "url": "https://www.ensembl.org/id/ENSBTAG00000035265" } ] } } ], "crossref": [ { "id": "E1BL89", "url": "https://alphafold.ebi.ac.uk/entry/E1BL89", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000035265", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000035265", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BL89", "url": "https://www.orthodb.org/?gene=E1BL89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31592:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31592:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14802", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14802", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SR97", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SR97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SR97-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SR97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL89", "url": "https://www.uniprot.org/uniprotkb/E1BL89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL89-1", "url": "https://www.uniprot.org/uniprotkb/E1BL89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSLDLIQSIEDDPLLDTQHLPHHSLHAHFRPRFHPLPTVIIANLLLLIHLVFVILAFLTGVLCSYPNPMEDKCPGNYTNPLKVQTVIILGKVILWILYFLLERYIQYHHCKVRNRGYNKIYRSTRHLKRLPLMIHSTGSTALLLLLCLQHSFPEPSTWYLDLILATLALELICSLTCLLVYTVKIQKFNKAKPQPDVLEEEKIYAYSNNITSETGFRPLSSLEELVEKQGDIIVYLKRHNALLSQRLLAFSSSDLGSQPSGI", "length": 263, "header": "tr|E1BL89-1|E1BL89_BOVIN Isoform 1 of Transmembrane protein 192 OS=Bos taurus OX=9913 GN=TMEM192 PE=3 SV=4 CANONICAL=E1BL89-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SR97-1", "url": "https://www.uniprot.org/uniprotkb/E1BL89/entry#A0AAA9SR97-1", "sequence": { "sequence": "MLGALGRDGVGSSLGGGDPSARGHRAAGSLDLIQSIEDDPLLDTQHLPHHSLHAHFRPRFHPLPTVIIANLLLLIHLVFVILAFLTGVLCSYPNPMEDKCPGNYTNPLKVQTVIILGKVILWILYFLLERYIQYHHCKVRNRGYNKIYRSTRHLKRLPLMIHSTGSTALLLLLCLQHSFPEPSTWYLDLILATLALELICSLTCLLVYTVKIQKFNKAKPQPDVLEEEKIYAYSNNITSETGFRPLSSLEELVEKQGDIIVYLKRHNALLSQRLLAFSSSDLGSQPSGI", "length": 289, "header": "tr|A0AAA9SR97-1|E1BL89_BOVIN Computationally mapped isoform of Transmembrane protein 192 OS=Bos taurus OX=9913 GN=TMEM192 PE=3 SV=1 CANONICAL=E1BL89-1" }, "locus": { "chromosome": "17", "start_pos": 209904, "end_pos": 181816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116627.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116627.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086590.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086590.1" } ] } }, { "isoform_ac": "E1BL89-1", "url": "https://www.uniprot.org/uniprotkb/E1BL89/entry#E1BL89-1", "sequence": { "sequence": "MGSLDLIQSIEDDPLLDTQHLPHHSLHAHFRPRFHPLPTVIIANLLLLIHLVFVILAFLTGVLCSYPNPMEDKCPGNYTNPLKVQTVIILGKVILWILYFLLERYIQYHHCKVRNRGYNKIYRSTRHLKRLPLMIHSTGSTALLLLLCLQHSFPEPSTWYLDLILATLALELICSLTCLLVYTVKIQKFNKAKPQPDVLEEEKIYAYSNNITSETGFRPLSSLEELVEKQGDIIVYLKRHNALLSQRLLAFSSSDLGSQPSGI", "length": 263, "header": "tr|E1BL89-1|E1BL89_BOVIN Isoform 1 of Transmembrane protein 192 OS=Bos taurus OX=9913 GN=TMEM192 PE=3 SV=4 CANONICAL=E1BL89-1" }, "locus": { "chromosome": "17", "start_pos": 205243, "end_pos": 181816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049751.5", "url": "https://www.ensembl.org/id/ENSBTAT00000049751.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046602.5", "url": "https://www.ensembl.org/id/ENSBTAP00000046602.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BL89", "url": "https://www.uniprot.org/uniprotkb/E1BL89" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "E1BL89", "url": "https://www.uniprot.org/uniprotkb/E1BL89" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "E1BL89", "url": "https://www.uniprot.org/uniprotkb/E1BL89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BL89-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 263, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BL89-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BL89" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKX3-1", "uniprot_ac": "E1BKX3", "uniprot_id": "E1BKX3_BOVIN", "mass": { "chemical_mass": 152037.0, "monoisotopic_mass": 152037.0 }, "refseq": { "ac": "XP_010814254", "name": "myb-binding protein 1A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814254" }, "gene_names": [ { "name": "MYBBP1A", "type": "recommended", "evidence": [ { "id": "E1BKX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX3" } ] }, { "name": "MYBBP1A", "type": "synonym", "evidence": [ { "id": "XP_010814254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814254" } ] } ], "protein_names": [ { "name": "MYB binding protein 1a", "type": "synonym", "evidence": [ { "id": "E1BKX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX3/entry#names_and_taxonomy" } ] }, { "name": "myb-binding protein 1A", "type": "synonym", "evidence": [ { "id": "XP_010814254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814254" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKX3", "url": "https://www.uniprot.org/uniprotkb/E1BKX3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MYBBP1A", "url": "https://www.uniprot.org/uniprotkb/E1BKX3", "locus": { "chromosome": "19", "start_pos": 25023912, "end_pos": 25039779, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007430", "url": "https://www.ensembl.org/id/ENSBTAG00000007430" } ] } } ], "crossref": [ { "id": "ENSBTAG00000007430", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007430", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "513045", "url": "https://www.ncbi.nlm.nih.gov/gene/513045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513045", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513045", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VWKHDDP", "url": "https://omabrowser.org/oma/group/VWKHDDP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKX3", "url": "https://www.orthodb.org/?gene=E1BKX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13213:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13213:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5250924", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5250924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010814254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814254", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SS49", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SS49-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKX3", "url": "https://www.uniprot.org/uniprotkb/E1BKX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKX3-1", "url": "https://www.uniprot.org/uniprotkb/E1BKX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPASMEVTEPLAPGEAQKSGVRPADRHGLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRAKPKGSSEMKYALKRLITGLGGGREAARPCYSLALAQLLQSFEDIPLGSILQQIQEKHDLQKVKKGMMRPALFGNLFGVLALFQSGRLVKDSEALMKSVKLLQALGQHYNHLQEQPQKALVDILSQVPEAALQEILPKVLKPDLNSVLGSPEHLELFLLAQQKVPEKLEKLMGPVNLFSDENIPRLVTVLKTVANSVKKERKLPTVALDLLRLALQEDKFPWFWKEVVEQGLLKKQFWPASYLCFRLLGAALPLLSKEQLQLVMQGDLIRHYGEHMVTAKLPKQFKFAPEMNEYVGAFLEGCRGDPERQLALVVAFTSITNQGLPVVPTFWRVVQFLSPTALKGYVAWLQDMFLQPDLDSLVDFSTNNQKKTQDTSFHGPERAVFRLRKWIILRLVSIVDNLHVEKEEALIEEVARFCFFHSFFETKKPTSQIPESEQHFTLPLDGRTREVVCGAFFSLLQTLSTQFRLAPEQTADGRPWTYHLVQFADVLLNHSRNVAPLTAFTTQQRQAWDRMLKTLKELDTLSSEAKATAFQHLLLLVGIHLFKSPAESCDLLGDIQTCIKKSLGEKTRRTRSKATNPQEPPWVEVLVEILLSLLAQPSHLMRQVARSVFGHICAHLTLRALQLILDVLNPEESQDEDDNVVVTDDSEEQLLGGAEDKSSDGEDSKGSKVSESEEESDDDDSDEEDRDGDVDQGFREQLMAVLQAGKALGGADSEDDNDDEELGDEAMMALDKSLASLFAEQKLRIQARKDEKNKLQKEKALRRDFQIRVLDLIEVLVTKQPENPLVLELLEPLLLVIRRSMRSNSSAKQEQDLLHKTARIFTHHLCRSRHYCRTAGDRVETLYARLERLVQQAGQQADSSVALYHFNASLYLLRVLRGSTVDKPARKAQKKEKASKDASSQPQGPEAASCLDLSLVTPIYSSALSSFLTKRNSPLTVPMFLSLFSRHPMLCKSLLPIVVEHVTSHTRPRHQVQACLLLQKTLPTRELRVCFKDPEWKQLMGQTLGKVTEILRTLGEAETKSGHQKDLAALELLNTLFRNFHHEKLTMDLTAVLGVLQSQQLRLQQRLQQGEHSAGSSRLHDLYWQAMKFLGVQRPKSEKDTKEAPQATQQSPVSMKRKKKGFLPETKKRKKHKPEATTQEAAAAKPEATSGDQPPSAGKKKKKKKKMKKTKSPALSQMNGTPAAKSPTPEPPAVSPSTPTKTPKPQKKTQKLAQVNEATPLPHQSPEEPVAKKRQKKLPQKGVSGKSPQSALPRKKARLSLAIRSPSLLQSGAKKVQLRKAKKL", "length": 1353, "header": "tr|E1BKX3-1|E1BKX3_BOVIN Isoform 1 of MYB binding protein 1a OS=Bos taurus OX=9913 GN=MYBBP1A PE=1 SV=1 CANONICAL=E1BKX3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SS49-1", "url": "https://www.uniprot.org/uniprotkb/E1BKX3/entry#A0AAA9SS49-1", "sequence": { "sequence": "MAEPASMEVTEPLAPGEAQKSGVRPADRHGLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRAKPKGSSEMKYALKRLITGLGGGREAARPCYSLALAQLLQSFEDIPLGSILQQIQEKHDLQKVKKGMMRPALFGNLFGVLALFQSGRLVKDSEALMKSVKLLQALGQHYNHLQEQPQKALVDILSQVPEAALQEILPKVLKPDLNSVLGSPEHLELFLLAQQKVPEKLEKLMGPVNLFSDENIPRLVTVLKTVANSVKKERKLPTVALDLLRLALQEDKFPWFWKEVVEQGLLKKQFWPASYLCFRLLGAALPLLSKEQLQLVMQGDLIRHYGEHMVTAKLPKQFKFAPEMNEYVGAFLEGCRGDPERQLALVVAFTSITNQGLPVVPTFWRVVQFLSPTALKGYVAWLQDMFLQPDLDSLVDFSTNNQKKTQDTSFHGPERAVFRLRKWIILRLVSIVDNLHVEKEEALIEEVARFCFFHSFFETKKPTSQIPESEQHFTLPLDGRTREVVCGAFFSLLQTLSTQFRLAPEQTADGRPWTYHLVQFADVLLNHSRNVAPLTAFTTQQRQAWDRMLKTLKELDTLSSEAKATAFQHLLLLVGIHLFKSPAESCDLLGDIQTCIKKSLGEKTRRTRSKATNPQEPPWVEVLVEILLSLLAQPSHLMRQVARSVFGHICAHLTLRALQLILDVLNPEESQDEDDNVVVTDDSEEQLLGGAEDKSSDGEDSKGSKVSESEEESDDDDSDEEDRDGDVDQGFREQLMAVLQAGKALGGADSEDDNDDEELGDEAMMALDKSLASLFAEQKLRIQARKDEKNKLQKEKALRRDFQIRVLDLIEVLVTKQPENPLVLELLEPLLLVIRRSMRSNSSAKQEQDLLHKTARIFTHHLCRSRHYCRTAGDRVETLYARLERLVQQAGQQADSSVALYHFNASLYLLRVLRGSTVDKPARKAQKKEKASKDASSQPQGPEMLCKSLLPIVVEHVTSHTRPRHQVQACLLLQKTLPTRELRVCFKDPEWKQLMGQTLGKVTEILRTLGEAETKSGHQKDLAALELLNTLFRNFHHEKLTMDLTAVLGVLQSQQLRLQQRLQQGEHSAGSSRLHDLYWQAMKFLGVQRPKSEKDTKEAPQATQQSPVSMKRKKKGFLPETKKRKKHKPEATTQEAAAAKPEATSGDQPPSAGKKKKKKKKMKKTKSPALSQMNGTPAAKSPTPEPPAVSPSTPTKTPKPQKKTQKLAQVNEATPLPHQSPEEPVAKKRQKKLPQKGVSGKSPQSALPRKKARLSLAIRSPSLLQSGAKKVQLRKAKKL", "length": 1311, "header": "tr|A0AAA9SS49-1|E1BKX3_BOVIN Computationally mapped isoform of MYB binding protein 1a OS=Bos taurus OX=9913 GN=MYBBP1A PE=1 SV=1 CANONICAL=E1BKX3-1" }, "locus": { "chromosome": "19", "start_pos": 25039410, "end_pos": 25024916, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108513.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108513.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086929.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086929.1" } ] } }, { "isoform_ac": "E1BKX3-1", "url": "https://www.uniprot.org/uniprotkb/E1BKX3/entry#E1BKX3-1", "sequence": { "sequence": "MAEPASMEVTEPLAPGEAQKSGVRPADRHGLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRAKPKGSSEMKYALKRLITGLGGGREAARPCYSLALAQLLQSFEDIPLGSILQQIQEKHDLQKVKKGMMRPALFGNLFGVLALFQSGRLVKDSEALMKSVKLLQALGQHYNHLQEQPQKALVDILSQVPEAALQEILPKVLKPDLNSVLGSPEHLELFLLAQQKVPEKLEKLMGPVNLFSDENIPRLVTVLKTVANSVKKERKLPTVALDLLRLALQEDKFPWFWKEVVEQGLLKKQFWPASYLCFRLLGAALPLLSKEQLQLVMQGDLIRHYGEHMVTAKLPKQFKFAPEMNEYVGAFLEGCRGDPERQLALVVAFTSITNQGLPVVPTFWRVVQFLSPTALKGYVAWLQDMFLQPDLDSLVDFSTNNQKKTQDTSFHGPERAVFRLRKWIILRLVSIVDNLHVEKEEALIEEVARFCFFHSFFETKKPTSQIPESEQHFTLPLDGRTREVVCGAFFSLLQTLSTQFRLAPEQTADGRPWTYHLVQFADVLLNHSRNVAPLTAFTTQQRQAWDRMLKTLKELDTLSSEAKATAFQHLLLLVGIHLFKSPAESCDLLGDIQTCIKKSLGEKTRRTRSKATNPQEPPWVEVLVEILLSLLAQPSHLMRQVARSVFGHICAHLTLRALQLILDVLNPEESQDEDDNVVVTDDSEEQLLGGAEDKSSDGEDSKGSKVSESEEESDDDDSDEEDRDGDVDQGFREQLMAVLQAGKALGGADSEDDNDDEELGDEAMMALDKSLASLFAEQKLRIQARKDEKNKLQKEKALRRDFQIRVLDLIEVLVTKQPENPLVLELLEPLLLVIRRSMRSNSSAKQEQDLLHKTARIFTHHLCRSRHYCRTAGDRVETLYARLERLVQQAGQQADSSVALYHFNASLYLLRVLRGSTVDKPARKAQKKEKASKDASSQPQGPEAASCLDLSLVTPIYSSALSSFLTKRNSPLTVPMFLSLFSRHPMLCKSLLPIVVEHVTSHTRPRHQVQACLLLQKTLPTRELRVCFKDPEWKQLMGQTLGKVTEILRTLGEAETKSGHQKDLAALELLNTLFRNFHHEKLTMDLTAVLGVLQSQQLRLQQRLQQGEHSAGSSRLHDLYWQAMKFLGVQRPKSEKDTKEAPQATQQSPVSMKRKKKGFLPETKKRKKHKPEATTQEAAAAKPEATSGDQPPSAGKKKKKKKKMKKTKSPALSQMNGTPAAKSPTPEPPAVSPSTPTKTPKPQKKTQKLAQVNEATPLPHQSPEEPVAKKRQKKLPQKGVSGKSPQSALPRKKARLSLAIRSPSLLQSGAKKVQLRKAKKL", "length": 1353, "header": "tr|E1BKX3-1|E1BKX3_BOVIN Isoform 1 of MYB binding protein 1a OS=Bos taurus OX=9913 GN=MYBBP1A PE=1 SV=1 CANONICAL=E1BKX3-1" }, "locus": { "chromosome": "19", "start_pos": 25039410, "end_pos": 25024916, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009771.8", "url": "https://www.ensembl.org/id/ENSBTAT00000009771.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009771.5", "url": "https://www.ensembl.org/id/ENSBTAP00000009771.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1257, "start_aa": "Thr", "end_pos": 1257, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1257", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:513045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513045", "resource": "KEGG Pathway" }, { "id": "R-BTA-5250924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5250924", "resource": "Reactome", "description": "B-WICH complex positively regulates rRNA expression" } ], "orthologs": [ { "uniprot_canonical_ac": "O35821-1", "protein_name": "Myb-binding protein 1A", "gene_name": "Mybbp1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEMKSPTKAEPASPAEAPQGDRRSLLEHSREFLDFFWDIAKPDQETRLRATEKLLEYLRTRPSDSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIQLCDILGQIQEKYNLQAMNKAMMRPTLFANLFGVLALFQSGRLVKDKEALMKCVRLLKILSHHYNHLQGQPVKALVDILSEVPESMFQEILPKVLKGDMKVILSSPKYLELFLLARQRVPAELESLVGSVDLFSEDNIPSLVNILKVAANSVKKEQKLPDVALNLLRLALQENKFERFWKEVLEEGLLKKPSYTSSYMCFRLLGASLPLLSDEQLQLVMRGDLIRHFGEHMVVSKSQNPLRFIPEISAYVGTFLEGCQDDPKRQFTVMVAFTAITNQGLPVMPTFWRVTRFLNTEALQNYVTWLRDMFLQPDLDSLVDFSTANQKRVQVASLNVPERTVFRLRKWIIHRLVSLVDHLHLEKDEAVVEQIARFCLFHAFFKTKKATPQIPETKQHFSFPLEDGNRGVIVSAFFSLLQTLSVKFRQTPDLAENGKPWTYRLVQLADMLLKHNRNVANVTPLTAQQRQAWDQMMSTLKELEAQSSETRAIAFQHLLLLVGLHLFKSPAESCDVLGDIQTCIKKSMEQNLRRSRSRAKASQEPVWVEVMVEILLSLLAQPSNLMRQVVRSVFGHVCSHLTPRGLQLILAVLNPETNEDEEDNVVVTDTDEKQLKHGEDADSDSEDSKNSESDVDSEDGEESEEEDRDKDVDPGFRQQLMEVLQAGNALGGEEEEEEELGDEAMMALDQNLASLFAEQKMRIQARHEEKNKLQKEKQLRRDFQIRALDLIEVLVTKQPEHPLILELLEPLLNIIQRSMRSRGSTKQEQDLLHKTARIFMHHLCRARHYCHEVEPGAEALHAQVERLVQQAGNQADASVALYYFNASLYLLRVLKGNTTKRYQDGQKLEGADIKSEPKDSEVQTTSCLDLDFVTRVYSASLESLLTKRNSPLTIPMFLDLFSRYPVICKNLLPIVVQHVAGSSRPRHQAQACLLLQKALSARELRVCFEDPEWEQLISQVLGKTTQTLQTLGEAQSKGEHQRELSILELLNTVFRIVNHEKLSVDLTAFLGMLQGKQQKLQQNLQQGNHSSGSSRLYDLYWQAMNLLGVQRPKSEKKNVKDIPSDSQSPISTKRKKKGFLPETKKRKKLKSEGTTSEKKAASQQDAVTEGAMPAATGKDQPPSTGKKRRKRVKANTPSQVNGVTVAKSPAPNNPTLSPSTPPAKTPKVQKKKEKLSQVNGSTPVSPVEPESKKHQKALSTKEVKRRSSQSALPKKRARLSLVSRSPSLLQSGIRKRRVARRRVQTP", "length": 1344 }, "evidence": [ { "id": "E1BKX3", "url": "https://omabrowser.org/oma/group/E1BKX3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P39985-1", "protein_name": "rRNA processing protein POL5", "gene_name": "POL5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTGKVNRDLFFKLASDLREERLHAAVALIKDLSALDLPDDAEEWSYVLNRLIKGLSSDRNSARLGFSLCLTEVINLAVNMPPGQRPKGLESTNEFLSTLSTILNVNVNEGTKKSMKGKDERGILFGKLFGLKSLLNEPLFSEIFVKDLEKGNTEFFIRFTEQLIDLALKKNWIKEPCFFTLFQTMKMLLPFMDESSAEKILLIYDKYDLTLTNEGLSTYLLLKYEGDESLIPSVLDLKNPGWKDNDPLARGNLPLLTKVLRNSSVIPDANGGLKETKKQKNTNWNPRLHFVWSVLLPLFGNGKLENTSHISKKRKKTNNKKVQNSIQFPEFWKMAVDESFFNEKASSERKYLGFLIIDAAFKAVPGSYIGFCFSQNVMRTLINQSIDSQRVLNKISQLTLDSIVKACEEDSANRLVPCLNAMLFGPHGSINFDKLTKSGTVSKLIAIKELPSTVLAQLLDVFFLQLQDKKGVLSHTLFALDSILHIVRAHKVEINDMDIMKPVLRPIVYMAFFKHTSDDLKLEQLHELAKERLYSILGELTINKEIRCKDPEINSWQYLTLKLILDIENSHVGDLINPLDENLENIKNEAISCLSKVCRSRTAQSWGLSTLLSMCLVQLYAGDTDSISVIEELCEFSKHENNSMVGITEILLSLLAQKKALLRKLSLIIWQQFIEEVGLEELQILLDILKARENKQGFAQLFEGEEEFEEIKEENDASEDESKTGSESESESESDSDDADEKDEEDEANEDILNIDKEATSALVKALNLPDNIVNDKGEVDLDQLEGLSDDGGDDEDEESMDDEKMMELDDQLSEIFKRRKEALSSISTGNQRKFEVKQSRENVISFKHRVVDMLAVYVKYCEKLTLANKSEHSNNLGGSLSKLVYFIIPMLKCVNETLDRPLADKISKLLKGKIFKIKVTAFKDMNKDIELMDLLKKTHKLMLTSKPGQHAAVFYSMCSTSSLFLSKLYVEIGGNDKLDELIDLYTATTKEWMQKGKCGPNIFIDFINWLSSKKQTVMDKE", "length": 1022 }, "evidence": [ { "id": "E1BKX3", "url": "https://omabrowser.org/oma/group/E1BKX3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55BC8-1", "protein_name": "DNA polymerase V family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTSTVEVTTTNNNGVVTPLDALNIEIKKKDAILQCFYDIASMDNETRLQSITTLVQTLEEIQSVFKPEDHKDISRIVPKIIEKSEIFNNNLSPELNYTLKRLVIGLASTRDSARIGFSMALSEILHSFKQVIELPWFFDFLAFHMDLSGKNLSEKESHFGRLFGMMSIIRSSRLEGLPIIQNQPSKSINYDFNRPPSENMIECIVEQLLYISKKRSIYSELSFEILSSLFEQLSDSNFDKLWPFIKPIIPQSQDEYTPDLLSLLLLISKKFKKFNLIKQTVGWKHPSILNISNLSLLKNIFSESCKSHPRIHKVWRITFEILLADHEENATLLEFWKLIVEDNLFKTTSMNKRYLGLQLFEMLLPLVHPDIINDIFSENVIANLSESLKPTSPLHEVGSLAFQSIPRTAEISSQHRLALILFFSNNSHHHNQNPQNQQQQKQKFEQSISVDVINELVKDLDEDSIKIYLNSLYKLFINVVSSSSSSSNDNSNNNSNNEDEDDMVIDEMNNEEKSEKYIDSSRHWILSQIGHISKDLVKRPTESLIKLEPMLLELLQFLYFHSYYLTCESKPVAAVATATPVTKGKKKVTAAVVAAPVKTFTEELFTSKPKSEISQSIRDQCFIRFCSVLEELSYLTLESTKQQTTSYEGTMSNGEFWASKMASFQYDLLKKGSTDSDRPQLSTFLPMGIKPIDRIMKIVQSIQLKQKSAEKRLNQLVGFELLFVHVSLHYLTDAQEISEIIEDLTSAFEELTNPQPPQKSTTKKRSAPEQDKPQPFMVLLDVLISLLDKPIHILRTIIKQIFSIFADNISFQVLEHILTMIKAPTDELFNGLDGNGDDDEDNEDDDEFKPISPEELKQSKENSDDEDEEDDEEEEEEEEEEEEEDSDDDNSVNPELVARLKQTMGKHLLLDEDDEDEDLLEPTEEEAKMMDNYLKEVFKSKKEKKSNYQDIKTQTINLKSRLIDLLESYVKKFITNPNEYIFKMIPLMIEATSFDEPSISNRFISLFKNKFSQIRTTTDKSVNVQELNQLLSSLFDTILSSKHTGSSKDKEQQNNNSSAYILSGHAIYMIVRVLLSIKPPVATVAVQQTPSKKSTKSTKSTTNNNVVVEQPTPSEYGSLDIKLFSTKLDSIIECLLDRNNIVPSRFFTEFAQRFPTVIWASIKKVTTIIESPQNDYNSKKILDVLSSIVKRKDSYGTSGKNLLNNASDILTTLCNSLNGKEKQLKPNSIFDHLNIINQIIFSCLQIIKSSNSGDSTSLSNKLGSESCKLLESTLCRLYKLNNKQNIKDTSKKILLSLGLENNEIFESEKQKKLEKQQKKETQQKERQSNKEKSKQEIIERIEQSKQDRKNKSTDSKIDNKNKSKPKKKVEDDMEVVDEIFQDVDEKSKKNKKDSDKKSNDNNNKKDTTKKSTDNKSTDKKSTDKKSTDKKSTDKKSTDKKSTEKKSTKEDSQPMKKKQKK", "length": 1461 }, "evidence": [ { "id": "E1BKX3", "url": "https://omabrowser.org/oma/group/E1BKX3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6DRL5-1", "protein_name": "Myb-binding protein 1A-like protein", "gene_name": "mybbp1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVAVMQTDMGETENSAVRPKVTDAKGILKQNRQFLDYFWDIAKPDRQIRLKAIEDLINYLKNSEQADELKYTLKRLVDGLSHTREDARSGYSVALAQLLSVFEEISLKSTLNSVKEKHNLLTASKKLIRNAVFGNFFGVLALSQSTRLHKEPQVMLECVQLLQSLSEYREHLRDLPRKTMVDILSETSQDVFEEVLFSALQSDLTSALKSPEQLELLLVALQKFPSVLKPKKLKKLLGTTAVITKQNMPRLVEVLKTAARSVKKENILPAVALDLLQVSLREDNFEMFWTDAIITGMMSEMPGPTHYLSFRLLGASLPLLSIPQLQFVLSGDVMRQYGEHTMSAQMPDRFKFAPEMAGYVGEFMQSCTDPDKQLVVVLGFTQLTNQGNPVVPSYWKALENMHPSAVQRYVDWLIEAFCKPQLENCLDFSTRRQKGNQEAAVESESCVSRFRKWIIPRLTFIVENQQIKKQEALVMKVVRFIFFHAFFEVKKPTSEIPETTQALSVPINQQTRTAVVSGFYSLLQALNSMMVLGESVEVQGLNFRRIVGVQADGSMWIYSVFQFASMLLNQNKYVKSLQSFSPEQRQGWDSVLESVEALRKKAKTASSPEHTAFQQLFLLIGIQMFTSPEESLDLLKDLQTCMEKAQAKKSKKKKATDEPHWVEVIVEILLSLVSQPSRLVRSVCKTVFGRICPHLTQAALSSILNVLDPNKDEDESGVVVTDDKKRKLKEEDEDDDDEEEDDDNDEGDDDDDDDDEEEGGEEGEESSDSSDDEEEDEAMEEGQEVDQNFRLELMKVLQGQNALATEEDGSDDEELDDAAMMKLDGSLASLFLEQRKKIQAKKDEKDRLNKEKGLVRDFKIKVLDMVEVFLSKQGFSPLVLGMVEPLLSVIENGMSSESSQPEQDYLRRVADIFRNRLCRGKFYCKEIDGREAELHEMLERLIGRAQKLTDSSVALYYFSAALYVLKVLRGSVVDQELSTMGKVEVERATTCLKNALTSFMTKRKSPLTGAMFIDLFHRFPVLCVNLMDTALENITAGLRDHQQGQACFIMLKALQCKHVKNLMTGEQTTELYKKVVDQLTKSLENVQCKNKTAHDKVVKALELCLHVVKIVLNQKMRVNLELLQDVLASMNAEGCLEKTGKLEDTYWSVMRLFGVIKPKMEKVKKVPEAEQTEETTKKKKGFLPETKKRKNRKKPTILEGKETETPVEKTPEGASGEGKKNKNKKKNKKRKQQAGEETQDQPTPKKAKMQQQQQQKQKKKKKKKGADGE", "length": 1269 }, "evidence": [ { "id": "E1BKX3", "url": "https://omabrowser.org/oma/group/E1BKX3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7TPV4-1", "protein_name": "Myb-binding protein 1A", "gene_name": "Mybbp1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEMKSPTKAEPATPAEAAQSDRHSLLEHSREFLDFFWDIAKPDQETRLRATEKLLEYLRTRPNDSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIPLCDILDQIQEKYSLQAMNKAMMRPSLFANLFGVLALFQSGRLVKDKEALMKSVQLLKILSQHPNHLQGQPIKALVDILSEVPESMFQEILPKVLKGNMKVILRSPKYLELFLLAKQRVPTKLESLMGSVDLFSEDNIPSLVNILKVAANSVKKEHKLPNVALDLLRLALKESRFELFWKKVLEEGLLKNPSWTSSYMCFRLLGASLPLLSEEQLQLVMRGDLIRHFGENMVISKPQNLFKIIPEISTYVGTFLEGCQDDPKRQLTMMVAFTTITNQGLPVMPTFWRVTRFLNAEALQSYVAWLRDMFLQPDLNSLVDFSTANQKRAQDASLNVPERAVFRLRKWIIHRLVSLVDHLHLEKDEAVVEQIARFCLFHAFFKTKKATPQIPETKQHFSFPLDDRNRGVFVSAFFSLLQTLSVKFRQTPDLAENGKPWTYRLVQLADMLLNHNRNVTSVTSLTTQQRQAWDQMMSTLKELEARSSETRAIAFQHLLLLVGLHIFKSPAESCDVLGDIQTCIKKSMEQNPRRSRSRAKASQEPVWVEVMVEILLSLLAQPSNLMRQVVRSVFGHICPHLTPRCLQLILAVLSPVTNEDEDDNVVVTDDADEKQLQHGEDEDSDNEDNKNSESDMDSEDGEESEEEDRDKDVDPGFRQQLMEVLKAGNALGGVDNEEEEELGDEAMMALDQNLASLFKEQKMRIQARNEEKNKLQKEKKLRRDFQIRALDLIEVLVTKQPEHPLILELLEPLLNVIQHSMRSKGSTKQEQDLLHKTARIFMHHLCRARRYCHEVGPCAEALHAQVERLVQQAGSQADASVALYYFNASLYLLRVLKGNTNKRHQDGHKLHGADTEDSEDQAANCLDLDFVTRVYSASLESLLTKRNSSLTVPMFLSLFSRYPVICKNLLPVLAQHVAGPSRPRHQAQACLMLQKTLSARELRVCFEDPEWEQLITQLLGKATQTLQTLGEAQSKGEHQKELSILELLNTLLRTVNHEKLSVDLTAPLGVLQSKQQKLQQSLQQGNHSSGSNRLYDLYWQAMRMLGVQRPKSEKKNAKDIPSDTQSPVSTKRKKKGFLPETKKRKKLKSEGTTPEKNAASQQDAVTEGAMPAATGKDQPPSTGKKKRKRVKASTPSQVNGITGAKSPAPSNPTLSPSTPAKTPKLQKKKEKLSQVNGATPVSPIEPESKKHHQEALSTKEVIRKSPHPQSALPKKRARLSLVSRSPSLLQSGVKKRRVASRRVQTP", "length": 1344 }, "evidence": [ { "id": "E1BKX3", "url": "https://omabrowser.org/oma/group/E1BKX3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BQG0-1", "protein_name": "Myb-binding protein 1A", "gene_name": "MYBBP1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESRDPAQPMSPGEATQSGARPADRYGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRGRPKGSEMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLHQVKKAMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALVDILSEVSKATLQEILPEVLKADLNIILSSPEQLELFLLAQQKVPSKLKKLVGSVNLFSDENVPRLVNVLKMAASSVKKDRKLPAIALDLLRLALKEDKFPRFWKEVVEQGLLKMQFWPASYLCFRLLGAALPLLTKEQLHLVMQGDVIRHYGEHVCTAKLPKQFKFAPEMDDYVGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVTPTFWRVVRFLSPPALQGYVAWLRAMFLQPDLDSLVDFSTNNQKKAQDSSLHMPERAVFRLRKWIIFRLVSIVDSLHLEMEEALTEQVARFCLFHSFFVTKKPTSQIPETKHPFSFPLENQAREAVSSAFFSLLQTLSTQFKQAPGQTQGGQPWTYHLVQFADLLLNHSHNVTTVTPFTAQQRQAWDRMLQTLKELEAHSAEARAAAFQHLLLLVGIHLLKSPAESCDLLGDIQTCIRKSLGEKPRRSRTKTIDPQEPPWVEVLVEILLALLAQPSHLMRQVARSVFGHICSHLTPRALQLILDVLNPETSEDENDRVVVTDDSDERRLKGAEDKSEEGEDNRSSESEEESEGEESEEEERDGDVDQGFREQLMTVLQAGKALGGEDSENEEELGDEAMMALDQSLASLFAEQKLRIQARRDEKNKLQKEKALRRDFQIRVLDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSSSSKQEQDLLHKTARIFTHHLCRARRYCHDLGERAGALHAQVERLVQQAGRQPDSPTALYHFNASLYLLRVLKGNTAEGCVHETQEKQKAGTDPSHMPTGPQAASCLDLNLVTRVYSTALSSFLTKRNSPLTVPMFLSLFSRHPVLCQSLLPILVQHITGPVRPRHQACLLLQKTLSMREVRSCFEDPEWKQLMGQVLAKVTENLRVLGEAQTKAQHQQALSSLELLNVLFRTCKHEKLTLDLTVLLGVLQGQQQSLQQGAHSTGSSRLHDLYWQAMKTLGVQRPKLEKKDAKEIPSATQSPISKKRKKKGFLPETKKRKKRKSEDGTPAEDGTPAATGGSQPPSMGRKKRNRTKAKVPAQANGTPTTKSPAPGAPTRSPSTPAKSPKLQKKNQKPSQVNGAPGSPTEPAGQKQHQKALPKKGVLGKSPLSALARKKARLSLVIRSPSLLQSGAKKKAQVRKAGKP", "length": 1328 }, "evidence": [ { "id": "E1BKX3", "url": "https://omabrowser.org/oma/group/E1BKX3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FGF4-1", "protein_name": "DNA polymerase V family", "gene_name": "MSJ1.26", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGSKKRSNDDSTELVENDNLPDSSIVKKKKSKTEKMNTVANYDSDTAAAAAEVPGVASSGKDMEKKKMRKASDKQRRLEAALKKNNGVGASRPKPIPVAVNSNSDEADDESLPSAAASSSSLPLNYFTDLASSDASVREAAAESLVLRLQEIQKQYEMLPDKESVDGGLMLEAEKNDGLDNCAPHLRYALRRLIRGVSSSRECARQGFALGLTLPVSVISSINVESLLNLIADSLSVSSSMTGQDIKECLLGRLFAYGALARSGRLIEDWQSDKDSPIIKEFTNALIGLAAKKRYLQEPAVHILLDFVDKLPTEPVVTHVMEAPELYKWFEQATEVGNPDALLLALKLHEKVSVDHPIFSKLLPVPFSSGKFFSADHLTAIGNCLKESTFCQPRVHSLWPVIVDMLLPEAVVQSEDVVSVSSSSKKQKRNRKSNPVEEEATNNIRNFCEVFMEGDLLSSTHVRKHLAFDILLLLLPKLPASFIQHVLSLKFVQCLMDILSTKDSWLHKVATHFLVELMDWVKDDDTKRVAVTMALQKHSEGKFDNITRTKTVKVLAAELETEDGCTLYLQNLMNLFVDEQHVPEESSNMKWSLEPCSLNSDQSQTTDDNSDNGSNEEKDSVGTTGNSDVLKSWVIESLPGILKHAKLSPEAKLRLQKQILKFLAVQGLFLASLGTEVTSFELQEKFKWPKTATPAALCQMCIEQLQLLLSNSQKIEKPLSKGNALEQPDDPVSYFMKFLSTLQNIPSVSLFRSLNEADEKAFKELQETESKLLKEERNCGLSTDPNKFHALRHLVVQLLLQILLHPGEFSEAATELSVCCDKAFSSLDLLKSDGQGEADDEEEPAVMDVLVDTLLSLLPHSSAPMRSSIEQVFKYFCQDVTNDGLLRMLRVIKKDLKPSRHQEDQDSDDLDDDEEDCLAIEDAEEENEEMGETGESDEQTDDSEAVTGVVPMAVDREVPENSDDSDDDDGMDDDAMFRMDTYLAQIFKEKRNQAGGETAQSQLVLFKLRVLSLLEIYLHENSDKPQVMTVYLNLVQAMLNPSTAESSLPLLQRIWGIIQKKIFKAKEFPKDESMEFSALASLLEKNLKLAAKPFKSKKSGVDPSKKKQSAAWNRYKMITHLGQNSTYWVMKIIDSRKFSETELEKILDVFRSAVTGYFDSRKSQLKIDFLEEVFRRRPWIGHQLFGFLLEASVNANVEFRRLEALDLITETLRSLIPINENTQADSRKTMTTHLKELILLIKELVGNMPEAKVRRAQVRKFCGRIFQMVSSLKLTKSFLKGLGQDGRTACEDAFGDLFLNLKNTEH", "length": 1306 }, "evidence": [ { "id": "E1BKX3", "url": "https://omabrowser.org/oma/group/E1BKX3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BKX3", "url": "https://www.uniprot.org/uniprotkb/E1BKX3" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "E1BKX3", "url": "https://www.uniprot.org/uniprotkb/E1BKX3" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "E1BKX3", "url": "https://www.uniprot.org/uniprotkb/E1BKX3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1BKX3", "url": "https://www.uniprot.org/uniprotkb/E1BKX3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BKX3", "url": "https://www.uniprot.org/uniprotkb/E1BKX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1248, "end_pos": 1250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 873, "end_pos": 875, "annotation": "n_glycosylation_sequon" }, { "start_pos": 936, "end_pos": 938, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1257 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1248, "end_pos": 1250 }, { "start_pos": 558, "end_pos": 560 }, { "start_pos": 873, "end_pos": 875 }, { "start_pos": 936, "end_pos": 938 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", 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"IVTFLIKCLFSRRLIAMFLLLHFIVLMDVKDCALTEGSTITPLCPKGYFPCGNLSQCLPRAFHCDGVEDCGNGADEENCGDTSGWATIFGTVHGNANNVALTQECFLDQYPQRCVCKGTELECVNAGLKSVPVVSSNVTLLSLKKNNIHSLSDKVFIKYTELKKIFLQRNCITYISRKAFFGLHNLQILYLNHNCITTLRPGVFKDLHQLTWLILDDNPISRISQRLFTGLNSLFFLSMVNNHLQVLPKQMCAQMPQLNWMDLEGNGIKFLTNSTFLSCSSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNMISELPPHIFKDLKCLQKLNLSSNPLLYLHKSQFGSLKQLQSLDLERIEIPNINTRMFQPMKNLSYIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNILRVFVWVIAFITCFGNLFVIGMRSFIKAENTTHATSIKILCCADCLMGVYLFFIGLCDLKYRGQYQKYALLWMESLQCRLLGFLAMLSTEVSVLLLTYLTLEKFLAVVFPFSNIRPGKWQTLAVLICIWIVGFLIAVTPLWKEDYFGNFYGKNGVCFPLYYDQTEDIGSKGYSLGIFLGVNLLAFLIIVFSYTVMFCSIQKTALQTSDERSHMGREVAVANRFFFIVFSEAICWIPVFVIKILSLSRVEIPDTITSWVVIFFLPVNSALNPILYTLTTSFFKDKLKQLLHKHRRKSIFKTKKKSVSTSIMWADDSSALKPGALSKINLEDNIVKPIS", "length": 753, "header": "tr|E1BKC2-1|E1BKC2_BOVIN Isoform 1 of Relaxin receptor 2 OS=Bos taurus OX=9913 GN=RXFP2 PE=4 SV=4 CANONICAL=E1BKC2-1" }, "locus": { "chromosome": "12", "start_pos": 29274797, "end_pos": 29213292, "strand": "+", 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BE11-1", "uniprot_ac": "E1BE11", "uniprot_id": "E1BE11_BOVIN", "mass": { "chemical_mass": 612631.0, "monoisotopic_mass": 612631.0 }, "refseq": { "ac": "NP_001179466", "name": "hemicentin-1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179466" }, "gene_names": [ { "name": "HMCN1", "type": "recommended", "evidence": [ { "id": "E1BE11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ] }, { "name": "HMCN1", "type": "synonym", "evidence": [ { "id": "NP_001179466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179466" } ] } ], "protein_names": [ { "name": "Hemicentin-1", "type": "recommended", "evidence": [ { "id": "E1BE11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE11/entry#names_and_taxonomy" } ] }, { "name": "Fibulin-6", "type": "synonym", "evidence": [ { "id": "E1BE11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE11/entry#names_and_taxonomy" } ] }, { "name": "hemicentin-1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001179466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179466" } ] } ], "function": [ { "annotation": "Involved in transforming growth factor beta-mediated rearrangement of the podocyte cytoskeleton which includes reduction of F-actin fibers and broadening, flattening and elongation of podocytes. Plays a role in basement membrane organization. May promote cleavage furrow maturation during cytokinesis in preimplantation embryos. May play a role in the architecture of adhesive and flexible epithelial cell junctions. May play a role during myocardial remodeling by imparting an effect on cardiac fibroblast migration.", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11#function" }, { "database": "UniProtKB", "id": "ARBA00053381", "url": "https://www.uniprot.org/uniprotkb/ARBA00053381#function" }, { "database": "UniProtKB", "id": "A0AAA9SUB9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUB9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HMCN1", "url": "https://www.uniprot.org/uniprotkb/E1BE11", "locus": { "chromosome": "16", "start_pos": 67244873, "end_pos": 66705833, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015235", "url": "https://www.ensembl.org/id/ENSBTAG00000015235" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015235", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015235", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00198", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00198", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00255", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00255", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "521326", "url": "https://www.ncbi.nlm.nih.gov/gene/521326", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "E1BE11", "url": "https://www.ebi.ac.uk/intact/interactors/id:E1BE11*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521326", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521326", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPSIHWM", "url": "https://omabrowser.org/oma/group/FPSIHWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BE11", "url": "https://www.orthodb.org/?gene=E1BE11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179466", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179466", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SUB9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUB9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE11-1", "url": "https://www.uniprot.org/uniprotkb/E1BE11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISWDMIHTIFLLALLYPSRAQDAIPQSEVEAEEIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLFNFALVPFHDPEIGPVTVTTDPKKFQYELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRSHIGYRVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLEQAENTWKIPFDPSLKEVTVSLSGPSPMIEIHNPLGKLIKKGFGLNELLNIHNSAKVVNVKEPEAGIWTVKTSSTGRHSVRITGLSTIDFRAGFSRKPTLDFKKTVSRPVQGIPTYVLLNTSGISIPAKVDRLELLSISGSSLKTIPVKYYPDRKPYGIWNISDFIPPNEAFFLKVTGYDKDGFLFQRVSSVSFSSIVPDAPKVTMPKKTPGYYLQPGQIPCAVDSLLPFTLSFVRNGATLGVDQYLKESASVTWDIEEVTLADEGAYECVAVSTAGIGRAQTFFDVSEPPPVIQVPSNVTVTPGETAVLTCLVVSAVGYNLTWQRNDRDIRLTDTAGMRILANLSLELRSVKFSDAGEYRCVVSNEGGSSTEAVFLTVQEPPKVTVMPKNQSFTAGSEVSIMCSATGYPKPKIAWTMNDVFIMGSHRYRMTSEGNLFIKNAVPKDAGIYGCLASNSAGMDKQTSTLRYIEAPKLIVVQSELLVALGDTTVMECKTSGVPPPQVKWFKGDLELKPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAVNDAGRATGRITLDVGSPPVFIQEPTDVSVEIGSNVTLPCYVQGYPEPKIKWRRVDNMPIFSRPFSVSSISQLRTGDLFISNLWASDKGTYICEAENQFGKIQSQTTVTVTGLVAPLIGISPPVTSVIEGQQLTLPCALLAGNPIPERRWIKNSAMLVQNPYITVRSDGSLHIERVRLQDGGEYTCVASNVAGITNKTTTVDVHVLPTIQHGQQILSTIEGIPVTLPCKASGIPKPSIAWSKKGELIFTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNAAGYAKRKVQLTVYVRPRVFGDQRGPSQDKPVEISVFAGEEVTLPCEVKGLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRVSDSGMYLCVATNIAGNVTQSVKLNVHVPPKIQRGPKVMKVQVGQRVDIPCSAQGTPLPVITWFKGGGAVLVDGLQHIRHPDGTLSIKQAVLSDAGIYTCVATNIAGSDETEITLHVQEPPILEDLEPPYNTPFQERVANQRIAFPCPAKGTPKPTIKWLRNGRELTGQEPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERRYNLKVHVPPVIKDKEQVTNVSVLVNQPTSLFCEVEGTPSPIIMWYKDDVQVTESSSIQIVNNGKILKLFRTSPEDAGGYSCKAVNVAGTSQKHFNIDVLVPPTIIGAGSPGEVSVVLNQNTTLECQVKGTPFPVIRWLKDGKPLFLGDPNIEILDRGQVLHLKNARRSDKGRYQCSVSNAAGKQAKDIKLTIYIPPSIKGGNVTTEVSALINSIIKLECETRGLPMPAITWYKDGQPVISSSQALYVEKGQFLHIPRAQVSDSAAYKCLVTNVAGTAEKSFHVDVYVPPVIEGDLAEPLNKQVKVAHSLTLECKAAGNPPPVLTWLKDGVPVKASDNIRIEAGGKKLEITSALEVDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCQVTGSPLPTIMWLKDGQLIDERDGFRILLNGHKLVIAQAQVSDTGLYRCVATNTAGDHRKEFEVTVHVPPTIKSSGLSERAVLKYKPITLQCIANGIPNPSITWLKDGQPVNTAQGNLKIQSSGRLLQIAKALMEDAGRYTCVATNAAGETQQHIQLHVHEPPSLDDAGKMLNETVVVNSPVQLECKAAGTPSPAITWYKDNRPLSDSSSVTFLNRGQIINIESAQITDAGIYKCVAINSAGATELFYSLQVHVPPSIFGSNNMVAVVVNNLVRLECEARGIPAPSLTWLKDGSPVTSFVNGIQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVAPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSVTENGSVLKIEDAQVQDSGRYTCEATNVAGKTEKNYNVNIWVPPNISGSDEAAQLTVIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRILSGGRQLQISVAEKSDAGLYSCMASNVAGTAKKDYSLQVYIRPTISNSGSHPTEIIVTRGKSVSLECEVEGVPQPAVTWMKDGRPLTKGRGMEIMDEGRVVQLKNVHVSDTGRYVCVAMNIAGMTDRKYDLSVHTPPSIIGNHRTPENISVVEKSSVSLNCEASGIPLPSITWLKDGWPVNLSSSLRILSGGRILRLMQTRTEDAGQYTCVVRNAAGEERKIFRLSVLVPPHIMGENTFEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQLLKEDDTHHLMSGGRFLQIVNAQVSHTGRYTCLASNTAGDKSKSFSLNVLVSPIIAGVDGDGSPEDVTVILNSPTSLVCEAYSYPPATITWFKNGTPLESNQNIRILPGGRTLQILNAQEDDAGRYACVATNEAGEMIKHYEVKVYIPPIINKGDLLGPGLSPREVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVTIAAGGHTLQIKEAQISDTGRYTCVASNVAGEDELDFDVNIQVPPSFQKLWEIGNRVDTGRRGEAKDVIINNPISLYCETNAAPAPTLTWYKDGHPLTSSERVLILPGGRVLQIPRAKVEDAGRYMCVAVNEAGEDSLQYDIRVLLPPVIKGANGDLPEEVTVLVNKSVTMECSSSGSPTPRSSWQKDGQPLLEDERHTFLSNGRILQVLNSQITDIGRYVCVAENTAGSAKKYFNFNVHVPPSVIGPNPENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKPNTNALIVPGGRTLQIIRAKVSDGGEYTCVAINQAGESKKKVSLTVYVPPSIKDHGSESLSVVNVREGTSVSLECGSNAVPPPVITWYKNGRMLTESARLEILADGQMLHITKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPENEVTVETVSNPVTLTCDATGIPPPSIAWLKNHRPIENSGSLEVHILSGGRKLQIARSQHSDSGNYTCIASNMEGKAQKHYILSIQVPPNVADAEIPSEVSVLLGENVELVCSANGIPTPLIQWLKDGKPIVNSETERIRVAADSSTLNIYGALPSDMGKYTCVATNPAGEEDRIFNLNVYVPPAIRGNKEEAEKLMALVDTSINIECRATGMPPPQINWLKNGLPLPLSSHIRLLSGGQVIRIVRAQASDVAVYTCVASNRAGVDNKHYSLQVLVPPSLDNGMGTEEITIVKGSSTSMTCFTDGTPAPRMSWLRDGRPLGLDAHLSISSQGMVLQLIKAETEDSGRYTCIASNEAGEVSKHFILKILEPPHINGSEEPMEMSVIVNNPLELTCMASGIPAPKITWMKDGRPLPQMDQMQTLGGGEVLRISSTQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTGEPQDFTVLRNRQVTLECKSDAVPPPVITWLKNGERLQATPRIRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPSIKSGPQSLVIHLNKSTLLECFAEGVPAPRITWRKDGAVLSGSHARYSVLENGFLRIQSAQVTDGGRYLCMATSAAGTDRRRIDLQVHVPPSIAPGPTNISVTVNVQTTLACEATGIPKPSVNWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNDAGEDKRAVDLTVQVPPSIADEPTDFLVTKHTPTVITCTASGVPFPSIHWMKNGVRLLPRGEGYRILSSGAIEILDTQLSHAGRYTCVARNSAGSAHRHVSLHVQEPPVIQPQPSELDVILNNPILLPCEATGTPSPFIIWQKEGISVISSGRSHAVLPRGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHPKEYITVVDKPIMLPCKADGLPPPDIMWHKDGHVIVESVRQRILSSGALQIAFAQPGDAGQYTCMAANVAGSSSTSTKLTVHVPPRIQSTEVHYTVNENSQAVLPCVADGIPTPAINWKKDNVPLANLLGKYTVEPYGELILENVVLEDSGTYTCIANNAAGEDTHTISLTVHVLPTFTELPGDVSLNKGEQLRLNCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERISKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPTIQWSRRGIDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETIINAGSKVILNCQATGEPRPTITWSRQGHSILWDERINVLSNNSLHIAAAQKEDTSEYECVARNLMGSVLVRVPVIVQVPGGFSQWSAWRPCSATCGKGIQKRSRLCNNPSPANGGKPCQGSDSEMQNCHQKPCPVDGNWSEWSPWEECTRSCGRGNRTRTRTCNNPSAQHGGRPCEGTAVEIIMCNIRPCPVHGAWSTWQPWGTCSVSCGKGTQTRARLCNNPPPSFAGSYCDGAETQIQVCNERHCPIDGKWATWTSWSACSVSCGGGARQRTRDCSDPAPQYGGNKCEGSDVQSDFCNSDSCPTHGNWSPWSGWGICSRTCNGGQMRRYRTCDNPRPSNGGRACGGPDSQIQRCNTDMCPVDGSWGNWHSWSWCSTSCGGGEKTRERLCNNPIPSKSGRPCPGDATQVSRCNIQVCPGGPQRARGSVIGSINDVEFGIAFLNATVTDSPNSDTRIIHAKITNVPRSLGPAMRKIVSILNPIYWTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEILRMTHVARGLDSDGALLVDIIVSGYVLQLQSPAEVTVKDYTEDYVQTGPGQLYAYSTRLFTIDGVSVPYTWTHTVLYDEAQGRMPFLVETLHASSVESDYNQLEETLGFKIHASISKGERSNQCPPGFALDSVGPFCADENECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGGYTCHAGQDCDNTIGSYRCVVHCGTGFRRTSDGLSCQDINECQESSPCHHRCFNAIGSFHCGCEPGYQLKGRKCVDINECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDVDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGLGRPCLDINECEQVPKPCAYQCFNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGNQYSSYNLARFSPMRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASLDTCVDINECENTDTCQHECKNTFGSYQCICPPGYQLMLNGKTCQDIDECLEQNVRCGPNRMCFNMRGSYRCIETPCPPDYQRDPVSGFCLKNCPPNDLECALSPYALEYKLVSLPFGIAANQDLIRLVAYTQDGVMHPRTTFLMIDEEQTVPFALRDENLKGVVYTIRPLQEPETYRMRVRALSYGANGTVEYQTTFIVYIAVSAYPY", "length": 5635, "header": "tr|E1BE11-1|E1BE11_BOVIN Isoform 1 of Hemicentin-1 OS=Bos taurus OX=9913 GN=HMCN1 PE=4 SV=3 CANONICAL=E1BE11-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SUB9-1", "url": "https://www.uniprot.org/uniprotkb/E1BE11/entry#A0AAA9SUB9-1", "sequence": { "sequence": "MISWDMIHTIFLLALLYPSRAQDAIPQSEVEAEEIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLFNFALVPFHDPEIGPVTVTTDPKKFQYELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRSHIGYRVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLEQAENTWKIPFDPSLKEVTVSLSGPSPMIEIHNPLGKLIKKGFGLNELLNIHNSAKVVNVKEPEAGIWTVKTSSTGRHSVRITGLSTIDFRAGFSRKPTLDFKKTVSRPVQGIPTYVLLNTSGISIPAKVDRLELLSISGSSLKTIPVKYYPDRKPYGIWNISDFIPPNEAFFLKVTGYDKDGFLFQRVSSVSFSSIVPDAPKVTMPKKTPGYYLQPGQIPCAVDSLLPFTLSFVRNGATLGVDQYLKESASVTWDIEEVTLADEGAYECVAVSTAGIGRAQTFFDVSEPPPVIQVPSNVTVTPGETAVLTCLVVSAVGYNLTWQRNDRDIRLTDTAGMRILANLSLELRSVKFSDAGEYRCVVSNEGGSSTEAVFLTVQEPPKVTVMPKNQSFTAGSEVSIMCSATGYPKPKIAWTMNDVFIMGSHRYRMTSEGNLFIKNAVPKDAGIYGCLASNSAGMDKQTSTLRYIEAPKLIVVQSELLVALGDTTVMECKTSGVPPPQVKWFKGDLELKPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAVNDAGRATGRITLDVGSPPVFIQEPTDVSVEIGSNVTLPCYVQGYPEPKIKWRRVDNMPIFSRPFSVSSISQLRTGDLFISNLWASDKGTYICEAENQFGKIQSQTTVTVTGLVAPLIGISPPVTSVIEGQQLTLPCALLAGNPIPERRWIKNSAMLVQNPYITVRSDGSLHIERVRLQDGGEYTCVASNVAGITNKTTTVDVHVLPTIQHGQQILSTIEGIPVTLPCKASGIPKPSIAWSKKGELIFTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNAAGYAKRKVQLTVYVRPRVFGDQRGPSQDKPVEISVFAGEEVTLPCEVKGLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRVSDSGMYLCVATNIAGNVTQSVKLNVHVPPKIQRGPKVMKVQVGQRVDIPCSAQGTPLPVITWFKGGGAVLVDGLQHIRHPDGTLSIKQAVLSDAGIYTCVATNIAGSDETEITLHVQEPPILEDLEPPYNTPFQERVANQRIAFPCPAKGTPKPTIKWLRNGRELTGQEPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERRYNLKVHVPPVIKDKEQVTNVSVLVNQPTSLFCEVEGTPSPIIMWYKDDVQVTESSSIQIVNNGKILKLFRTSPEDAGGYSCKAVNVAGTSQKHFNIDVLVPPTIIGAGSPGEVSVVLNQNTTLECQVKGTPFPVIRWLKDGKPLFLGDPNIEILDRGQVLHLKNARRSDKGRYQCSVSNAAGKQAKDIKLTIYIPPSIKGGNVTTEVSALINSIIKLECETRGLPMPAITWYKDGQPVISSSQALYVEKGQFLHIPRAQVSDSAAYKCLVTNVAGTAEKSFHVDVYVPPVIEGDLAEPLNKQVKVAHSLTLECKAAGNPPPVLTWLKDGVPVKASDNIRIEAGGKKLEITSALEVDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCQVTGSPLPTIMWLKDGQLIDERDGFRILLNGHKLVIAQAQVSDTGLYRCVATNTAGDHRKEFEVTVHVPPTIKSSGLSERAVLKYKPITLQCIANGIPNPSITWLKDGQPVNTAQGNLKIQSSGRLLQIAKALMEDAGRYTCVATNAAGETQQHIQLHVHEPPSLDDAGKMLNETVVVNSPVQLECKAAGTPSPAITWYKDNRPLSDSSSVTFLNRGQIINIESAQITDAGIYKCVAINSAGATELFYSLQVHVPPSIFGSNNMVAVVVNNLVRLECEARGIPAPSLTWLKDGSPVTSFVNGIQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVAPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSVTENGSVLKIEDAQVQDSGRYTCEATNVAGKTEKNYNVNIWVPPNISGSDEAAQLTVIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRILSGGRQLQISVAEKSDAGLYSCMASNVAGTAKKDYSLQVYIRPTISNSGSHPTEIIVTRGKSVSLECEVEGVPQPAVTWMKDGRPLTKGRGMEIMDEGRVVQLKNVHVSDTGRYVCVAMNIAGMTDRKYDLSVHTPPSIIGNHRTPENISVVEKSSVSLNCEASGIPLPSITWLKDGWPVNLSSSLRILSGGRILRLMQTRTEDAGQYTCVVRNAAGEERKIFRLSVLVPPHIMGENTFEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQLLKEDDTHHLMSGGRFLQIVNAQVSHTGRYTCLASNTAGDKSKSFSLNVLVSPIIAGVDGDGSPEDVTVILNSPTSLVCEAYSYPPATITWFKNGTPLESNQNIRILPGGRTLQILNAQEDDAGRYACVATNEAGEMIKHYEVKVYIPPIINKGDLLGPGLSPREVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVTIAAGGHTLQIKEAQISDTGRYTCVASNVAGEDELDFDVNIQVPPSFQKLWEIGNRVDTGRRGEAKDVIINNPISLYCETNAAPAPTLTWYKDGHPLTSSERVLILPGGRVLQIPRAKVEDAGRYMCVAVNEAGEDSLQYDIRVLLPPVIKGANGDLPEEVTVLVNKSVTMECSSSGSPTPRSSWQKDGQPLLEDERHTFLSNGRILQVLNSQITDIGRYVCVAENTAGSAKKYFNFNVHVPPSVIGPNPENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKPNTNALIVPGGRTLQIIRAKVSDGGEYTCVAINQAGESKKKVSLTVYVPPSIKDHGSESLSVVNVREGTSVSLECGSNAVPPPVITWYKNGRMLTESARLEILADGQMLHITKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPENEVTVETVSNPVTLTCDATGIPPPSIAWLKNHRPIENSGSLEVHILSGGRKLQIARSQHSDSGNYTCIASNMEGKAQKHYILSIQVPPNVADAEIPSEVSVLLGENVELVCSANGIPTPLIQWLKDGKPIVNSETERIRVAADSSTLNIYGALPSDMGKYTCVATNPAGEEDRIFNLNVYVPPAIRGNKEEAEKLMALVDTSINIECRATGMPPPQINWLKNGLPLPLSSHIRLLSGGQVIRIVRAQASDVAVYTCVASNRAGVDNKHYSLQVLVPPSLDNGMGTEEITIVKGSSTSMTCFTDGTPAPRMSWLRDGRPLGLDAHLSISSQGMVLQLIKAETEDSGRYTCIASNEAGEVSKHFILKILEPPHINGSEEPMEMSVIVNNPLELTCMASGIPAPKITWMKDGRPLPQMDQMQTLGGGEVLRISSTQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTGEPQDFTVLRNRQVTLECKSDAVPPPVITWLKNGERLQATPRIRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPSIKSGPQSLVIHLNKSTLLECFAEGVPAPRITWRKDGAVLSGSHARYSVLENGFLRIQSAQVTDGGRYLCMATSAAGTDRRRIDLQVHVPPSIAPGPTNISVTVNVQTTLACEATGIPKPSVNWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNDAGEDKRAVDLTVQVPPSIADEPTDFLVTKHTPTVITCTASGVPFPSIHWMKNGVRLLPRGEGYRILSSGAIEILDTQLSHAGRYTCVARNSAGSAHRHVSLHVQEPPVIQPQPSELDVILNNPILLPCEATGTPSPFIIWQKEGISVISSGRSHAVLPRGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHPKEYITVVDKPIMLPCKADGLPPPDIMWHKDGHVIVESVRQRILSSGALQIAFAQPGDAGQYTCMAANVAGSSSTSTKLTVHVPPRIQSTEVHYTVNENSQAVLPCVADGIPTPAINWKKDNVPLANLLGKYTVEPYGELILENVVLEDSGTYTCIANNAAGEDTHTISLTVHVLPTFTELPGDVSLNKGEQLRLNCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERISKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPTIQWSRRGIDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETIINAGSKVILNCQATGEPRPTITWSRQGHSILWDERINVLSNNSLHIAAAQKEDTSEYECVARNLMGSVLVRVPVIVQVPGGFSQWSAWRPCSATCGKGIQKRSRLCNNPSPANGGKPCQGSDSEMQNCHQKPCPVDGNWSEWSPWEECTRSCGRGNRTRTRTCNNPSAQHGGRPCEGTAVEIIMCNIRPCPVHGAWSTWQPWGTCSVSCGKGTQTRARLCNNPPPSFAGSYCDGAETQIQVCNERHCPIDGKWATWTSWSACSVSCGGGARQRTRDCSDPAPQYGGNKCEGSDVQSDFCNSDSCPTHGNWSPWSGWGICSRTCNGGQMRRYRTCDNPRPSNGGRACGGPDSQIQRCNTDMCPVDGSWGNWHSWSWCSTSCGGGEKTRERLCNNPIPSKSGRPCPGDATQVSRCNIQVCPGGPQRARGSVIGSINDVEFGIAFLNATVTDSPNSDTRIIHAKITNVPRSLGPAMRKIVSILNPIYWTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEILRMTHVARGLDSDGALLVDIIVSGYVLQLQSPAEVTVKDYTEDYVQTGPGQLYAYSTRLFTIDGVSVPYTWTHTVLYDEAQGRMPFLVETLHASSVESDYNQLEETLGFKIHASISKGERSNQCPPGFALDSVGPFCADENECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGGYTCHAGQDCDNTIGSYRCVVHCGTGFRRTSDGLSCQDINECQESSPCHHRCFNAIGSFHCGCEPGYQLKGRKCVDINECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDVDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGLGRPCLDINECENTDTCQHECKNTFGSYQCICPPGYQLMLNGKTCQDIDECLEQNVRCGPNRMCFNMRGSYRCIETPCPPDYQRDPVSGFCLKNCPPNDLECALSPYALEYKLVSLPFGIAANQDLIRLVAYTQDGVMHPRTTFLMIDEEQTVPFALRDENLKGVVYTIRPLQEPETYRMRVRALSYGANGTVEYQTTFIVYIAVSAYPY", "length": 5518, "header": "tr|A0AAA9SUB9-1|E1BE11_BOVIN Computationally mapped isoform of Hemicentin-1 OS=Bos taurus OX=9913 GN=HMCN1 PE=4 SV=1 CANONICAL=E1BE11-1" }, "locus": { "chromosome": "16", "start_pos": 67244680, "end_pos": 66706032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105361.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105361.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088930.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088930.1" } ] } }, { "isoform_ac": "E1BE11-1", "url": "https://www.uniprot.org/uniprotkb/E1BE11/entry#E1BE11-1", "sequence": { "sequence": "MISWDMIHTIFLLALLYPSRAQDAIPQSEVEAEEIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLFNFALVPFHDPEIGPVTVTTDPKKFQYELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRSHIGYRVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLEQAENTWKIPFDPSLKEVTVSLSGPSPMIEIHNPLGKLIKKGFGLNELLNIHNSAKVVNVKEPEAGIWTVKTSSTGRHSVRITGLSTIDFRAGFSRKPTLDFKKTVSRPVQGIPTYVLLNTSGISIPAKVDRLELLSISGSSLKTIPVKYYPDRKPYGIWNISDFIPPNEAFFLKVTGYDKDGFLFQRVSSVSFSSIVPDAPKVTMPKKTPGYYLQPGQIPCAVDSLLPFTLSFVRNGATLGVDQYLKESASVTWDIEEVTLADEGAYECVAVSTAGIGRAQTFFDVSEPPPVIQVPSNVTVTPGETAVLTCLVVSAVGYNLTWQRNDRDIRLTDTAGMRILANLSLELRSVKFSDAGEYRCVVSNEGGSSTEAVFLTVQEPPKVTVMPKNQSFTAGSEVSIMCSATGYPKPKIAWTMNDVFIMGSHRYRMTSEGNLFIKNAVPKDAGIYGCLASNSAGMDKQTSTLRYIEAPKLIVVQSELLVALGDTTVMECKTSGVPPPQVKWFKGDLELKPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAVNDAGRATGRITLDVGSPPVFIQEPTDVSVEIGSNVTLPCYVQGYPEPKIKWRRVDNMPIFSRPFSVSSISQLRTGDLFISNLWASDKGTYICEAENQFGKIQSQTTVTVTGLVAPLIGISPPVTSVIEGQQLTLPCALLAGNPIPERRWIKNSAMLVQNPYITVRSDGSLHIERVRLQDGGEYTCVASNVAGITNKTTTVDVHVLPTIQHGQQILSTIEGIPVTLPCKASGIPKPSIAWSKKGELIFTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNAAGYAKRKVQLTVYVRPRVFGDQRGPSQDKPVEISVFAGEEVTLPCEVKGLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRVSDSGMYLCVATNIAGNVTQSVKLNVHVPPKIQRGPKVMKVQVGQRVDIPCSAQGTPLPVITWFKGGGAVLVDGLQHIRHPDGTLSIKQAVLSDAGIYTCVATNIAGSDETEITLHVQEPPILEDLEPPYNTPFQERVANQRIAFPCPAKGTPKPTIKWLRNGRELTGQEPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERRYNLKVHVPPVIKDKEQVTNVSVLVNQPTSLFCEVEGTPSPIIMWYKDDVQVTESSSIQIVNNGKILKLFRTSPEDAGGYSCKAVNVAGTSQKHFNIDVLVPPTIIGAGSPGEVSVVLNQNTTLECQVKGTPFPVIRWLKDGKPLFLGDPNIEILDRGQVLHLKNARRSDKGRYQCSVSNAAGKQAKDIKLTIYIPPSIKGGNVTTEVSALINSIIKLECETRGLPMPAITWYKDGQPVISSSQALYVEKGQFLHIPRAQVSDSAAYKCLVTNVAGTAEKSFHVDVYVPPVIEGDLAEPLNKQVKVAHSLTLECKAAGNPPPVLTWLKDGVPVKASDNIRIEAGGKKLEITSALEVDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCQVTGSPLPTIMWLKDGQLIDERDGFRILLNGHKLVIAQAQVSDTGLYRCVATNTAGDHRKEFEVTVHVPPTIKSSGLSERAVLKYKPITLQCIANGIPNPSITWLKDGQPVNTAQGNLKIQSSGRLLQIAKALMEDAGRYTCVATNAAGETQQHIQLHVHEPPSLDDAGKMLNETVVVNSPVQLECKAAGTPSPAITWYKDNRPLSDSSSVTFLNRGQIINIESAQITDAGIYKCVAINSAGATELFYSLQVHVPPSIFGSNNMVAVVVNNLVRLECEARGIPAPSLTWLKDGSPVTSFVNGIQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVAPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSVTENGSVLKIEDAQVQDSGRYTCEATNVAGKTEKNYNVNIWVPPNISGSDEAAQLTVIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRILSGGRQLQISVAEKSDAGLYSCMASNVAGTAKKDYSLQVYIRPTISNSGSHPTEIIVTRGKSVSLECEVEGVPQPAVTWMKDGRPLTKGRGMEIMDEGRVVQLKNVHVSDTGRYVCVAMNIAGMTDRKYDLSVHTPPSIIGNHRTPENISVVEKSSVSLNCEASGIPLPSITWLKDGWPVNLSSSLRILSGGRILRLMQTRTEDAGQYTCVVRNAAGEERKIFRLSVLVPPHIMGENTFEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQLLKEDDTHHLMSGGRFLQIVNAQVSHTGRYTCLASNTAGDKSKSFSLNVLVSPIIAGVDGDGSPEDVTVILNSPTSLVCEAYSYPPATITWFKNGTPLESNQNIRILPGGRTLQILNAQEDDAGRYACVATNEAGEMIKHYEVKVYIPPIINKGDLLGPGLSPREVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVTIAAGGHTLQIKEAQISDTGRYTCVASNVAGEDELDFDVNIQVPPSFQKLWEIGNRVDTGRRGEAKDVIINNPISLYCETNAAPAPTLTWYKDGHPLTSSERVLILPGGRVLQIPRAKVEDAGRYMCVAVNEAGEDSLQYDIRVLLPPVIKGANGDLPEEVTVLVNKSVTMECSSSGSPTPRSSWQKDGQPLLEDERHTFLSNGRILQVLNSQITDIGRYVCVAENTAGSAKKYFNFNVHVPPSVIGPNPENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKPNTNALIVPGGRTLQIIRAKVSDGGEYTCVAINQAGESKKKVSLTVYVPPSIKDHGSESLSVVNVREGTSVSLECGSNAVPPPVITWYKNGRMLTESARLEILADGQMLHITKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPENEVTVETVSNPVTLTCDATGIPPPSIAWLKNHRPIENSGSLEVHILSGGRKLQIARSQHSDSGNYTCIASNMEGKAQKHYILSIQVPPNVADAEIPSEVSVLLGENVELVCSANGIPTPLIQWLKDGKPIVNSETERIRVAADSSTLNIYGALPSDMGKYTCVATNPAGEEDRIFNLNVYVPPAIRGNKEEAEKLMALVDTSINIECRATGMPPPQINWLKNGLPLPLSSHIRLLSGGQVIRIVRAQASDVAVYTCVASNRAGVDNKHYSLQVLVPPSLDNGMGTEEITIVKGSSTSMTCFTDGTPAPRMSWLRDGRPLGLDAHLSISSQGMVLQLIKAETEDSGRYTCIASNEAGEVSKHFILKILEPPHINGSEEPMEMSVIVNNPLELTCMASGIPAPKITWMKDGRPLPQMDQMQTLGGGEVLRISSTQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTGEPQDFTVLRNRQVTLECKSDAVPPPVITWLKNGERLQATPRIRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPSIKSGPQSLVIHLNKSTLLECFAEGVPAPRITWRKDGAVLSGSHARYSVLENGFLRIQSAQVTDGGRYLCMATSAAGTDRRRIDLQVHVPPSIAPGPTNISVTVNVQTTLACEATGIPKPSVNWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNDAGEDKRAVDLTVQVPPSIADEPTDFLVTKHTPTVITCTASGVPFPSIHWMKNGVRLLPRGEGYRILSSGAIEILDTQLSHAGRYTCVARNSAGSAHRHVSLHVQEPPVIQPQPSELDVILNNPILLPCEATGTPSPFIIWQKEGISVISSGRSHAVLPRGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHPKEYITVVDKPIMLPCKADGLPPPDIMWHKDGHVIVESVRQRILSSGALQIAFAQPGDAGQYTCMAANVAGSSSTSTKLTVHVPPRIQSTEVHYTVNENSQAVLPCVADGIPTPAINWKKDNVPLANLLGKYTVEPYGELILENVVLEDSGTYTCIANNAAGEDTHTISLTVHVLPTFTELPGDVSLNKGEQLRLNCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERISKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPTIQWSRRGIDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETIINAGSKVILNCQATGEPRPTITWSRQGHSILWDERINVLSNNSLHIAAAQKEDTSEYECVARNLMGSVLVRVPVIVQVPGGFSQWSAWRPCSATCGKGIQKRSRLCNNPSPANGGKPCQGSDSEMQNCHQKPCPVDGNWSEWSPWEECTRSCGRGNRTRTRTCNNPSAQHGGRPCEGTAVEIIMCNIRPCPVHGAWSTWQPWGTCSVSCGKGTQTRARLCNNPPPSFAGSYCDGAETQIQVCNERHCPIDGKWATWTSWSACSVSCGGGARQRTRDCSDPAPQYGGNKCEGSDVQSDFCNSDSCPTHGNWSPWSGWGICSRTCNGGQMRRYRTCDNPRPSNGGRACGGPDSQIQRCNTDMCPVDGSWGNWHSWSWCSTSCGGGEKTRERLCNNPIPSKSGRPCPGDATQVSRCNIQVCPGGPQRARGSVIGSINDVEFGIAFLNATVTDSPNSDTRIIHAKITNVPRSLGPAMRKIVSILNPIYWTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEILRMTHVARGLDSDGALLVDIIVSGYVLQLQSPAEVTVKDYTEDYVQTGPGQLYAYSTRLFTIDGVSVPYTWTHTVLYDEAQGRMPFLVETLHASSVESDYNQLEETLGFKIHASISKGERSNQCPPGFALDSVGPFCADENECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGGYTCHAGQDCDNTIGSYRCVVHCGTGFRRTSDGLSCQDINECQESSPCHHRCFNAIGSFHCGCEPGYQLKGRKCVDINECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDVDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGLGRPCLDINECEQVPKPCAYQCFNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGNQYSSYNLARFSPMRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASLDTCVDINECENTDTCQHECKNTFGSYQCICPPGYQLMLNGKTCQDIDECLEQNVRCGPNRMCFNMRGSYRCIETPCPPDYQRDPVSGFCLKNCPPNDLECALSPYALEYKLVSLPFGIAANQDLIRLVAYTQDGVMHPRTTFLMIDEEQTVPFALRDENLKGVVYTIRPLQEPETYRMRVRALSYGANGTVEYQTTFIVYIAVSAYPY", "length": 5635, "header": "tr|E1BE11-1|E1BE11_BOVIN Isoform 1 of Hemicentin-1 OS=Bos taurus OX=9913 GN=HMCN1 PE=4 SV=3 CANONICAL=E1BE11-1" }, "locus": { "chromosome": "16", "start_pos": 67244680, "end_pos": 66706032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061144.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061144.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053678.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053678.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 532, "start_aa": "Thr", "end_pos": 532, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr532", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:521326", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521326", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3YXG0-1", "protein_name": "Hemicentin-1", "gene_name": "Hmcn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIAQEVVHTVFLVALFRSSLAGDGTPQSESRAEEIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLYNFALVPFHDPEIGPVTITTDPKKFQYELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRNHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLEHAVNTWKIPFDPSLKEVTVSLSGPSPVIEIRNPFGKLIKKGFGLNELLNIHNSAKVVNVKEPEAGMWTVKTSSSGRHSVRITGLSTIDFRAGFSRKPTLDFKKTMSRPVQGIPTYVLLNTSGISSPARVDRLELLSISGGSLKTIPVKHYPDRKPYGIWNISDFIPPDEAFFLKVTGYDKDGYLFQRVSSVSFSSIVPDAPKVTMPTRTLGYYLQPGQILCSVESFLPFTLSFMRDGIALGVDQYLRESASVNWDFTKVTLSDEGFYDCIAVSSAGTGRAQTFFDVSEPPPIIQLPNNVTVTPGERAVLACLVISAVDYNLTWQRSGRDIRLADSARIRTLANLSLELRSVKIGDAGEYRCVVSSEGGSAAASVFLTVQEKPKVTVMPKNQSFTGGSEISIMCSATGYPKPKIVWTMNEMFIMGSHRYRMTSEGTLFIKNAVPKDAGTYACLASNAAGTDKQTSTLRYIEAPKLVVEQSELLVALGDTTVMECKTSGIPPPQVKWFKGDLELRPSTFLSIDPLVGLLKIQETQDLDAGDYTCVAINEAGRATGRLTLDVGSPPVFIQEPSDVAVEIGSNVTLPCYVQGYPEPKIKWRRLDNMPVFSRPFSVSFISQLRTGALFISNLWASDKGTYICEAENQFGKIQSQTTVTVTGLVAPLIGISPSMASVIEGQPLTLPCTLLAGNPIPERRWMKNSAMLVQNPYITVRSDGSLHIERVRLQDGGKYTCVASNVAGTNNKTTSVAVHVLPSIQHGQQILSTIEGVPVTLPCRASGIPKPSITWSKKGELISTSSAKFSAGADGSLYVVSPGSEESGEYICTATNAAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEAILPCEAKSLPPPIITWAKDSQLISPFSPRHTFLPSGSMKITETRVSDSGMYLCVATNIAGNVTQSVKLSVHVPPKIQHGNRHIKVQVGQRVDILCNAHGSPPPVITWFKSGRPFLDGAQHPGSPDGTLSIEQAVISDAGVYTCAATNIAGSDEAEVTLHVQEPPSVEDLQPPFNTPFQERLANQRIEFPCPAKGTPKPTIKWLHNGREVTGQEPGVSILEDGALLVIASVTPHNNGEYICVAVNEAGTTERKYNLKVHVPPVIRDKEHVTNVSVLTSQLASLYCEVEGTPSPVITWYKDDIQVTESSTVQIVNNGKILKLFKVSAEDAGRYSCKAINIAGTSQKDFSVNVLVPPSILGASSPSEVSVVLNHNVTLQCPGTGVPFPAIHWFKDGKPLFLGDPNIELSDRGQSLHLRNARRSDKGRYQCTVSNAAGKQAKDIKLTVYVPPSIKGGNITTEISALLNSIVKLECETRGLPVPAITWYKDGQVVTSSSQALYIDKGQLLHIQRAQVSDSATYTCHAANVAGTAEKSFHVDIYVPPTIEGDLTAPSNKQVIIGQSLILECKAAGNPPPILTWLKDGVPVKASDNIHIEAGGKKLEILSALEVDRGQYICVATSVAGEREIKYEVDVLVPPAVEGGEETSYFIVLANNLLELDCQVSGSPPPTIMWLKGGQLIDERDGFKILLNGRKLVIAQAQVSDTGLYQCVATNIAGDHRKEFEVTVHVPPTIKSSDLPEKTVVRYKPVTLQCIANGIPNPSITWLKDDQPVNTAHGNLKIQSSGRVLQIAKALLEDAGRYTCVATNAAGEAHQHTQLHVHEPPSLDDAGKMRNETVVVNNPIQLECKATGKPLPVITWYKDSHPLSGSASAAFLKRGQVLEIGSAQISDAGIYKCVAINSAGATELFYSLQVHVPPSISGSSSMVEVVVNNLARLECEARGIPAPSLTWLKDGSPVSSFSNGIQILSGGRILALTSAQMSDAGRYTCVAVNAAGEKQRDIDLRVYAPPNIMGEEQNVSVLIGQAVELFCQSDAVPPPTLMWLKDGRPLLKRPGLSISENGSVLKIEDAQAGDTGRYTCEATNVAGKTEKNYNVNVWVPPSIYGSDELVQLTAIEGNLITLLCESSGIPPPDLTWKKKGSLVLADSAGRVHILSGGRRLQISIAEKADAGLYTCVASNVAGVAKKEYNLQVYIRPSITNSGGHRPEITVIRGKSISLECEVQGIPQPTVTWMKDGRPLTKGKGVEILDEGRILQLKNVHVSDTGRYVCVAVNVAGMTDKRYDLSVHAPPSIIGNHGVPENVSVVEKSSVSLTCEASGIPLPSITWLKDGWPVNLGSSVKILSGGRMLRLMQTRPEDAGQYTCIVRNAAGEDRKMFGLSVLVPPHIVGENTLEDVKIKEKQSVTLTCEVRGNPVPQITWHKDGQLLQEDEAHHMMSGGRFLQITNAQVSHTGRYTCLASNIAGDKSKSFRLNVFVSPTIAGVDSDGSPEDVIVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEKIKHYEVKVYIPPIIKKGDLLGPGLSPKEVKIRVNSSLTLECEAYAIPSASLRWYKDGQPLKSDDHVTIAASGHTLQIKEAQISDTGRYTCVASNLAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRSGEAKDVIINNPLSLHCETNAAPPPTLTWYKDGRPLTSSDRVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLRYDVHVLLPPVIKGANSDLPEEVTVLVNKSTQMECSSSGNPAPRNYWQKDGQILLEDEHHKFQSDGRSLQILNAQITDTGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPNHEHLSVVVNHFISLNCEVSGFPPPDLSWLKNEEPIKPNTNVLTVPGGRTLQIIRAKISDGGDYTCIAINQAGESKKKVSLTVHVPPSIKDHGSQSLSIVNVREGTSVSLECESNAVPPPVITWSKNGRMIPDSTNVEILTGGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPTIEGPETEVIVETISNPVTLTCDATGIPPPTITWLKNHKPIENSDPLEVHILSGGSKLQIARPQRSNSGNYTCVASNMEGKAQKNFILFIQVPPSVAGAEVPSEVSVLLGENVELVCNADGIPTPHLQWLRDGKPIVNGETERVRVTTDGSTLNIYRALTSDMGKYTCVATNPAGEEDRIFNLNVYVPPKIRGNKEEAEKLMALVDTSINIECKATGTPPPQINWLKNGLPLPISSHIRLLSAGQVVRIVRAQVSDIAVYTCVASNRAGVDSKHYSLQVFVPPNMDNAMGTEEITIVKGSSTSMTCFTDGTPAPSMSWLRDGQPLAPDAHLTVSTQGMVLQLIKAETEDTGKYTCVATNEAGEVSKHFVLKVLEPPHINGSEGPGEVSVIVNNPLELSCIASGIPAPKISWMKDGRPFLQTEQVQTLEGGAILRVSSAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGMDEAQDFTVLRNRQVTLECKSDAVPPPVIMWLKNREQLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFNLTVNVPPSIGGGPQSLVTLLNKSIALECRAEGVPAPRITWRKDGVVLAESHARYSILENGFLHIESAHVTDTGRYLCMATNVAGTDRRRIDLQVHVPPSIAMGPTNVTVTVNVQTTLACEATGIPKPSVTWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTASYECTVTSDAGEDKRAVDLTVQVPPTIADEPMDFLVTRQAPAVMTCSASGVPVPSIHWTKNGLRLLPRGDGYRILSSGAIEIPTTQLNHAGRYTCVARNAAGSAHRHVTLRVQEPPVIQPQPSELDVILNNPILLPCEATGIPTPFITWQKEGINVITSGKSLAILPSGSLQISRAVRGDAGTYMCVAQNPAGTALGKVKLNVQVPPVISSHQKEYVVTMDKPVSLLCETEGSPPPDITWHKDGHALTESIRQRILNSGALQIAFAQPDDAGQYTCMAANMAGSSSVSSTLTVHVPPRIQSTEVHFTVNENSQAVLPCVADGIPTPAIHWEKDGVLIANLLGKYTAQPYGELILENVVLEDSGTYTCVANNAAGEDTRIVTLAVHTLPTFTELPGDLSLNKGEQLRLSCKAVGIPLPKLTWTFNNNIIPAHFDSINGHSELVIEKVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPTIQWSRKGADIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVAANEAGMVERSMSLTLQSSPIITLEPVETVVDAGGRVILDCQAAGEPQPTITWSRQGQPISWDNRLSMLPNSSLYIAAARKEDTSEYECVARNLMGSVLVRVPVIVQVHGGFSLWSAWRPCSVTCGKGIQKRSRLCDNPPPANGGRPCQGADSEARHCHNKLCPVDGHWSEWSFWEDCSRSCGHGNQTRTRTCSNPPAQHGGRPCEGHAVETIMCNIRPCPVHGVWNAWQPWSACSKSCGKGSQTRMRLCNNPPPSFGGAHCSGAETQMQVCNERHCPVDGRWATWSSWSACTVSCGGGARKRTRDCSDPVPQYGGNKCEGTGVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPRPSNGGRACGGPDTQIQRCNTDMCPVDGSWGTWHSWSHCSVSCGGGERTRKRLCDNPVPTKGGRSCPGDATQVSRCNMQACPGGPQRARGSVIGNINDIEFGIAFLNATITDSPNTDTRVIQAKITNVPRSLGPAMRKIISILNPIYWTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEVLRMTHVARGLDSDGALLLDVIVSGQVLQLHSPAEVGVKDYTEDYIQTGPGQLYAYSTRLFTIDGISIPYTWNHTIFYDQAWGKMPFLVETLHASSIESDYNQLEETLGFKIHASISKGDRSNQCPSGFILDSVGPFCADEDECTAGNPCSHTCHNAIGAYYCSCPKGLTIAADGRTCQDIDECALGGHTCRAGQDCDNTIGSYRCVVHCGTGFRRTSDGLSCQDINECQESSPCHQRCFNVIGSFHCGCEAGYQLKGRKCIDVNECRQNVCRPDQHCKNTRGGYKCIDLCPSGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCACPRGYRSQGVGRPCIDINECEQVPKPCAHQCSNSPGSFKCICLPGQQLLGDGKSCAGLERLSNYGTQYSSYTLERFSPVRSDYQPSQHYRQYSQLYSSYSEYRNSRASFSRNRRTIRKTCPEGSEANHETCVDIDECQNRDTCQHECKNTIGSYQCVCPPGYRLMLNGKTCQDVDECLEQNVRCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVLGFCLKNCPPNDLECTLSPYALEYKLVSLPFGIAANQDLIRLVAYTQDGVMHPRTTFLMIDEEPAVPFALRDENLKGVVYTTRPLREAETYRMKVGALSYSANGTIEYQTTFIVYIAVSAYPY", "length": 5634 }, "evidence": [ { "id": "E1BE11", "url": "https://omabrowser.org/oma/group/E1BE11/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M4Q3-1", "protein_name": "Hemicentin-1", "gene_name": "Hmcn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIAQELVHTVFLVALFHSSLAGVGTPQSESRAEEIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLYNFALVPFHDPEIGPVTITTDPKKFQYELRELYVQGGGDCPEMSVGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRNHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLEHAVNTWKIPFDPSLKEVTVSLSGPSPVIEIRNPFGKLIKKGFGLNELLNIHNSAKVVNVKEPEAGMWTVKTSSSGRHSVRLTGLSTIDFRAGFSRKPTLDFKKTMSRPVQGIPTYVLLNTSGISSPARVDRLELLSISGGSLKTIPVKHYPDRKPYGIWNISDFIPPDEAFFLKVTGYDKEDYLFQRVSSVSFSSIVPDAPKVTMPTRTSGYYLQPGRILCSVESLLPFTLSFVRNGIALGVEQYLKESASVPWDFPKVTLSDEGFYECIAMNSAGTGRAQTFFDVSEPPPIIQVPNNVTVTPGERAVLACLVISAVDYNLTWQRSGRDVRLADSARIRTLANLSLELRSVKIGDAGEYRCVVSSEGGSAAASVFLTVQEKPKVTVMPRNQSFTGGSEVSIMCSATGYPKPKIVWTINEMFILGSHRYRMTAEGTLFIKNAVPKDAGTYSCLASNEAGTDEQTSTLRYIEAPKLVVVQSELLVALGDTTVMECKTSGIPPPQVKWFKGDLELRPSTFLSIDPLMGLLKIQETQDLDAGDYTCVAANDAGRATGSLTLDVGSPPVFIQEPSDVSMEIGSNVTLPCYVQGYPEPKIKWRRLDNMPVFSKPFSVSSISQLRTGALFISNLWASDKGTYICEAENQFGKIQSQTTVTVTGLVAPLIGISPSKASVIEGQPLTLPCTLLAGNPIPERRWMKNSAMLVQNPYITVRSDGSLHIERVRLQDGGEYTCVASNVAGTNNKTTSVAVHVLPTIQHGQQILSTIEGVPVTLPCRASGIPKPSITWSKKGELISTGNAKFSAGADGSLYVVSPGSEESGEYICTATNAAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEATLPCEAKSLPPPIITWAKDSQLISPFSPRHTFLPSGSMKITETRISDSGMYLCVATNIAGNVTQSVKLSVHVPPKIQHGNRHLKVQVGQRVDIPCNAHGSPPPVITWFKSGRPMPFNGVQHPGSPDGMLTIEQTTLSDAGTYTCTATNIAGSDEAEVTLHVQEPPTVEDLQPPFNTPFQERLANQRMAFPCPAKGTPKPTIKWLHNGKEVTGQEPGVSILEDGALLVIASVTPLNNGEYICVAVNEAGTTERKYNLRVHVPPVIKDKEHVSNVSVLVNQLASLYCEVEGTPSPVIMWYKDDIQVTESSTVQIVNNGKILKLFKASAEDTGRYSCKAINIAGTSQKDFSVNVLVPPSIQGAGSPNEVSVVLNHNITLQCPVRGTPFPAIHWFKDGKPLFLGDPNIELSDRGQNLHLRNARRSDKGRYQCSVSNAAGKQAKDIKLTLYVPPSIKGGNVTTEISALLNSVVKLECETRGLPVPAITWYKDGQVVTSSSQALYIDKGQFLHIPRAQVSDSATYTCHASNVAGTAEKSFHVDIYVPPIIEGDLTTPSSKQVVVGQSLVLECKAVGNPPPVLTWLKDGVPVKASDNIHIEAGGKKLEILSALEVDRGQYICVATSVAGEREIKYEVDVLVPPAVEGGDETSYFIVLANNLLELDCQVSGSPPPTIMWLKGGQLIDERDGFKILLSGRKLVIAQAQVSDTGLYQCVATNVAGDRRKEFEVTVHVPPTIKSSDLPEKTVVRYKPVSLQCIANGIPNPSITWLKDDQPVNTAPGNLRIQSSGRVLQIAKALLEDAGRYTCVATNAAGEAHQHTQLHVHEPPSLDDGGKMLNESVVVNNPIQLECKATGSPVPVLTWYKDSHPLAGSTSATFLKRGQILEIGSAQISDAGIYKCVAINSAGATELFYSLQVHVPPSISGSSSMVEVVVNNLARLECEARGIPAPSLTWLKDGSPVSSFSNGIQVLSGGRILALTSAQMSDTGRYTCVAVNAAGEKQRDFDLRVYAPPNIMGEEQNVSVLISQTVELFCQSDAVPPPTLMWFKDGRPLLKRPGLSISENGSVLMIEDAQAGDTGRYTCEATNVAGKTEKNYNVNIWVPPSIYGSDELVQLTAIEGNLITLLCESSGIPPPNLTWKKKGSLVLADAAGRVHILSGGRRLQISIAEKADAGLYTCVASNVAGIAKKEYNLQVYIRPSIANSGSHRPEITVIRGRSISLECEVQGIPQPTVTWMKDGRPLSKGKGVEILDEGRVLQLKNVHVSDTGRYVCVAVNVAGMTDKRYDLSVHVPPSIIGNHGVPENISVVEKSSVSLTCEASGIPLPSITWLKDGWPVSLGSSVKILSGGRMLRLMQTRPEDAGQYTCIVRNAAGEDRKMFGLSVLVPPHIVGDNTLEDIKIKEKQSVTLTCEVRGNPVPQITWHKDGQLLQEDEVHHMMSGGRFLQITNAQVSHTGRYTCLASNIAGDKSKSFSLNVFVSPTIAGVDSDGSPEDVIVILNSPTSLVCEAYSYPPATITWFKDGAPLESSRNLRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIIKKGDLLGTGLSPKEVKIRVNSSLTLECEAYAIPSASLRWYKDGQPLKSDHHVNIAENGHTLQIKEAQISDTGRYTCVASNLAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRSGEAKDVIINNPISLHCETNAAPPPTLTWYKDGRPLTSSDRVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDIHVLLPPVIKGANSDLPEEVTVLVNKSAQMECSSSGSPAPRNFWQKDGQPLLEDEHHKFLSDGRVLQILNAQITDTGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPNHEHLSVVVNHFISLTCEVSGFPPPDLNWLKNEQPIKPNTNVLIVPGGRTLQIIRAKVSDGGEYTCVAINQAGESKKKVSLTVHVPPSIKDHGSESLSIVNVREGTSVSLECESNAVPPPVITWSKNGRMIPDSSNVAILTGGQMLHIRRAEVADTGQYVCRAINVAGRDDKNFHLNVYVPPTIEGPETEVIVETMSNPVTLTCDATGIPPPTITWLKNHKPIENSDPLEAHILSGGSKLQIARLQRSNRGNYTCVASNMEGKAQKNYILSIQVPPSVAGAEVPSEVSVLLGENVELVCDADGIPIPRLQWLRDGKPIVSGETERVRVTTDGSTLNIYRALTSDMGKYTCVATNPAGEEDRIFNLNVYVPPKIRGNKEEAEKLMALVDTSLNIECKATGTPPPQISWLKNGLPLPISSHIRLLSAGQAIRIVRAQVSDVAVYTCVASNRAGIDSKRYSLQVFVPPNMDNAMGTEEITLVKGSSTSMTCFTDGAPTPSMSWLRDGQPLALDAHLTIGTQGMVLQLIKADTEDTGKYTCVASNEAGEVSKHFVLKVLEPPHINGSEGPGEVSVIVNNPLELSCIASGIPAPKISWMKDGRPFLQTEQVQTLEGGAILRVSSAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGVDEAQDFTVLRNRQVTLECKSDAVPPPVIMWLKNGEQLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPSISGGPQSLVTLLNKSIALECLAEGVPSPRITWRKDGVVLAESHARYSILENGFLHIQSAHITDTGRYLCMATNVAGTDRRRIDLQVHVPPSIAAGPTNVTVTVNVQTTLACEATGIPKPSINWRKDGHLLNVDQNQNSYRLLSSGSLIIISPSVDDTASYECTVTSDAGEDKRTVDLTVQVPPTIADEPMDFLVTRQAPAVMTCSASGVPLPSIHWTKNGIRLLPRGDGYRILSSGAIEISAAQLNHAGRYTCIARNAAGSVHRHVTLRVQEPPFIQPQPSELDVILNNPILLPCEATGIPTPFITWQKEGINVITSGKSLAVLPSGSLQISRAVQGDAGTYMCVAQNPAGTALGKIKLNVQVPPAISSHQKEYVVTMDKPVSLLCETEGSPPPDITWHKDGHALTESIRQRILNSGALQIAFAQPDDAGQYTCMAANMAGSSSMSTTLTVHVPPRIQSTEVHYTVNENSQVVLPCVADGIPTPAIHWERDSVLLANLLGKYTAQPYGELVLENVVLEDAGTYTCVANNAAGEDTHTVTLTVHALPTFTELPGDLSLNKGEQLRLSCKAVGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIEKVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPTIQWSRKGADVEISHRIRQLGNGSLAIYGTVNEDAGDYTCVAANEAGVVERSMSLTLQSSPMITLEPVETIVDAGGRVTLDCQAAGEPQPTITWSRQGRPIPWDNRLTMLPNSSLYIAAARKEDTSEYECVARNLMGSVLVRVPVIVQVHGGFSLWSAWRSCSVTCGKGIQKRSRLCNNPPPANGGRPCQGSESEARQCQNKLCPVDGHWSEWSFWEECSRSCGHGNQTRTRTCSNPPAQHGGRPCEGYAVETIMCNIRPCPVHGVWNAWQPWGSCSKSCGKGSQTRTRLCNSPPPSFGGAYCNGAETQMQVCNERHCPVDGKWAAWTSWSTCTVSCGGGTRKRTRDCSDPVPQYGGNKCEGTGVQSDFCNSDPCPTHGNWSPWSGWGMCSRTCNGGQMRRYRTCDNPRPSNGGRACGGPDTQIQRCNTDMCPVDGSWGTWHSWSHCSVSCGGGERTRKRLCDNPVPSKSGRSCPGDATQVSRCNMQACPGGPQRARGSVIGNINDIEFGIAFLNATITDSPNSDTRIIQATITNVPRSLGPAMRKIISILNPIYWTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEVLRMTHVARGLDSDGALLLDVIVSGHVLQLHSPAEVSVKDYTEDYIQTGPGQLYAYSTRLFTIDGISVPYTWNHTIFYDQAWGKMPFLVETLHASSVESDYNQLEETLGFKIHASISKGDRSNQCPSGFILDSAGPFCADEDECTAGNPCSHTCHNAIGAYYCSCPKGLTIAADGRTCQDIDECALGGHTCHAGQDCDNTIGSYRCVVHCGTGFRRTSDGLSCQDINECQESSPCHQRCFNVIGSFHCGCEAGYQLKGRKCIDVNECRQSVCRPDQHCKNTRGGYKCIDLCPSGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCACPRGYRSQGVGRPCVDINECDQVPKPCAHQCSNSPGSFKCICLPGQHLLGDGKSCAGLERLSSYGTQYSSYDLERFSPVRSGYQPRQHTRQQSQLYSSYSEYRNSRASFSRSRRTIRKTCPEGSEANHETCVDIDECQNRDTCQHECKNTIGSYQCVCPPGYRLMLNGKTCQDVDECLEQNVRCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVLGFCLKNCPPNDLECTLSPYALEYKLVSLPFGIAANQDLIRLVAYTQDGVMHPRTTFLMVDEEPAVPFALRDENLKGVVYTTRPLREAETYRMKVRALSYSANGTIEYQTTFIVYIAVSAYPY", "length": 5635 }, "evidence": [ { "id": "E1BE11", "url": "https://omabrowser.org/oma/group/E1BE11/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96RW7-1", "protein_name": "Hemicentin-1", "gene_name": "HMCN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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PAEVTVKDYTEDYIQTGPGQLYAYSTRLFTIDGISIPYTWNHTVFYDQAQGRMPFLVETLHASSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLECALSPYALEYKLVSLPFGIATNQDLIRLVAYTQDGVMHPRTTFLMVDEEQTVPFALRDENLKGVVYTTRPLREAETYRMRVRASSYSANGTIEYQTTFIVYIAVSAYPY", "length": 5635 }, "evidence": [ { "id": "E1BE11", "url": "https://omabrowser.org/oma/group/E1BE11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" }, { "name": "muscle tendon junction", "id": "GO:0005927", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005927", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" }, { "name": "basement membrane organization", "id": "GO:0071711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071711", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor activity", "id": "GO:0005007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005007", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" }, { "name": "fibroblast growth factor binding", "id": "GO:0017134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017134", "evidence": [ { "database": "UniProtKB", "id": "E1BE11", "url": "https://www.uniprot.org/uniprotkb/E1BE11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1158, "end_pos": 1160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1369, "end_pos": 1371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1470, "end_pos": 1472, "annotation": 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"start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3530, "end_pos": 3532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3689, "end_pos": 3691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3727, "end_pos": 3729, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3812, "end_pos": 3814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4401, "end_pos": 4403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4491, "end_pos": 4493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4588, "end_pos": 4590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4606, "end_pos": 4608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4759, "end_pos": 4761, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4894, "end_pos": 4896, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5267, "end_pos": 5269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5615, "end_pos": 5617, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" }, { "start_pos": 809, "end_pos": 811, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BE11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE11" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 5107, "end_pos": 5146, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BE11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE11" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 431, "end_pos": 517, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BE11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE11" }, { "id": "PS50993", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50993" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nidogen G2 beta-barrel", "eco_id": "ECO_0000259", "start_pos": 4871, "end_pos": 5093, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 532 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1158, "end_pos": 1160 }, { "start_pos": 1369, "end_pos": 1371 }, { "start_pos": 1470, "end_pos": 1472 }, { "start_pos": 1552, "end_pos": 1554 }, { "start_pos": 1929, "end_pos": 1931 }, { "start_pos": 2112, "end_pos": 2114 }, { "start_pos": 2155, "end_pos": 2157 }, { "start_pos": 2196, "end_pos": 2198 }, { "start_pos": 2395, "end_pos": 2397 }, { "start_pos": 2428, "end_pos": 2430 }, { "start_pos": 2612, "end_pos": 2614 }, { "start_pos": 2689, "end_pos": 2691 }, { "start_pos": 2887, "end_pos": 2889 }, { "start_pos": 2973, "end_pos": 2975 }, { "start_pos": 3221, "end_pos": 3223 }, { "start_pos": 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"o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2695 }, { "field": "total_sites", "count": 2170 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 2528 }, { "field": "total_sites", "count": 2062 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 167 }, { "field": "total_sites", "count": 145 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 52 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1BL04-1", "uniprot_ac": "E1BL04", "uniprot_id": "E1BL04_BOVIN", "mass": { "chemical_mass": 404067.0, "monoisotopic_mass": 404067.0 }, "refseq": {}, "gene_names": [ { "name": "XIRP2", "type": "recommended", "evidence": [ { "id": "E1BL04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ] } ], "protein_names": [ { "name": "Xin actin binding repeat containing 2", "type": "synonym", "evidence": [ { "id": "E1BL04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL04/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "XIRP2", "url": "https://www.uniprot.org/uniprotkb/E1BL04", "locus": { "chromosome": "2", "start_pos": 28988612, "end_pos": 29679076, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017743", "url": "https://www.ensembl.org/id/ENSBTAG00000017743" } ] } } ], "crossref": [ { "id": "ENSBTAG00000017743", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017743", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09442", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09442", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BL04", "url": "https://www.orthodb.org/?gene=E1BL04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22591", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22591", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22591:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22591:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08043", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08043", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SUE1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUE1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWG7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWG7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL04-1", "url": "https://www.uniprot.org/uniprotkb/E1BL04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLELKLVLRTICLVCVPHTVLHKDNLESSMFPMQKGSLNLLRQKWESSDYQKSEYSPRGSRCRLFQPQENKLLEPEGEVASTPGPPDPPSLLRSVREEILSVEPEEKCPEDKSDYSRDYGQLEVLKEDSLSGRHRIERFSIALDELRSVFEAPRSGNRQAGPAEYSRKEVEIERNLCSPTFKSHPGSQSDDSVKDSGKKDKETPYDKISSESGHSHIVEVTTGPIKPASGFAEDTAVQSKSASDLQEVVSLKERMAKYQAAVSRGDCRSFSANMLEESEMCTVPGGLARVKKQFEKDKIASSSNTFTQYQYQHQNRSEQEVIRSSQVDISRCSQEMERNEPEISEAHKIDVLGTEMVSHLEKHTEEINQASKLHQYVQETVIDTPEDEEIPKVSTKFLKEQFEKSVQEKVLYSDKELTPAKQIKMESESEETLKPSSIVGTSSTSYTSTSQRKETSTTRYSDHSATSSTLAQINATPSEKTEEFPPPPPDMLQPPVDVTAFSQSPELPNPPRKPPVPKELYSKQRNLYELNRLYKHIHPELRKNLEKDYISEVSEIVSRQMNAGSSVSADVQQARYVFENTNDSSQKGLNSEREHVEWDEILKGEVQSMRWIFENQPLDSINNGSPDEDNISKGIADQEIIAGGDVKYTTWMFETQPIDTLGDHSSGTEKHAEKIPELARGDVHTARWMFETKPLDSMNKLHQSQEESIATAIKDITGGDVKTVRYMFETQHLDQLGQLHSVDEMHLLQLRSELKEIKGNVKRSIKYFETQPLYVIRDGSGQMLEIKTVHREDVEKGDVRTARWMFETQPLDTINKDITEIKVVRGISMEENVKGGVHRAKWLFETQPLEKIKEETEEVIVEKETVIGTDVSKKCWMFETQPLDILKEVPDADHLKSEEIIGGDVQTTKQLFETLPIEALKDSPDVGKLQKITASEEEKGDVRHQKWIFETQPLEEIREDKKEYIRTVKLEEVDRGDVRNYTHIFESNNLIKFDASHKIEVEGVTRGAVELNKSLFETTPLYAIQDHLGKYHQVKTVQQEEILRGDVRSCRWLFETRPIDQFDESIHKYQIIRGISAQEIQTGNVKSAKWLFETQPLDSIKHFSNMEEVERKTEQVTDIVKGDVKTCRWLFETQPMESLYEKVSLMTGSKEIHKGDVKACTWLFETQPLDTIKDDSEATVKLQTVKQEEIHGGDVRTTCFLFETENLDSIQGEEGKEIKAIEMDIQAGDVSSMRHKFESQSLDSISSGSEEVLRKIKTLKAEDIQKGNVLNCRWLFENQPIDMIKESQEGDELVKTVTDIQGGNVRKGCFIFETFSLDEIKEESDYISTKKTITEEVIKGDVKSYRMLFETQPLYAIQDREGFYHEVTTVKKEEVIHGDVRGTRWLFETKPLDSINESETVYVIKSVTQEDIQKGDVSSVRYRFETQPLDQIAKESRDIVPTVDCIQGGDVRKSKQFFESENLDKNTYVRTVSVNEIQKGNVKTSTWLFETHTLDELRGEGSEYENIKTVTQEDMQKGDVKQAVWLFENQTLDSIKEADESITKITKEEIPPADVKTTTWLFETTPLHRFTENRVEKVEIIGKSIKETLGELYSQKVIEAPGIIIEADEVGDVRMAKYKLMNQASPEIQKEEIIKVDLRNIMVNLLSKRDCKKREILVSEEEKGNVNLTKTQLLNRSTEFHAEKEEIVSGDVQQAIKNLFSEERSVKKGILIQEDERGDINMTIYCLLHENAGDTIKREEIVGGDVKRTIHNLLSSISNNKISERAKIDASERGNVQFFTTCIETGALDYLRQLQTGSNEILTGRKQEKEEEIIGGDVEGTKLLLKKRQSQVERTVNETDIIPGDVRNTVKVFLTEPQNTSCKLPKEEIIKGDVKSTLNSLSQAVSQKTVAKTEEIIKGDMLTTLKSLKESSQKWKDSKQPDVVPGDIEKAIECLEKTARTRTEILKKELILDDLEASLRNLKETQTAFKEVNKSAVKDEVQTVMAGSKEEQKTGTHQVAVQRDKKSILQPRPGPFEPAARWQEGADILNQTINKSCHGDLMKERTEVNLPKAPKGPVKIVIDREQNNDALEKNLRKLSNSHQVGIWTDNMTEQHLRDEHVSGQLTSTLSVREHRKTKEAETEREQKKEAVFLQSIDKTIGKQQTETGQLRNDYQKIEAFPVKSPKNTKNTKTSTDTQSSRPGLTQGPVNRMVGETREVSEDFQKQTLLKQEKQYSNKDIMKKNVTLQPGWQTLPVNQDMSNVTEVKVSQKSHNQLKAIDKKQTDIHLKSQDFLMKTNTSKDLKMAMEMSFNPIKFNPENNAKENEFPLPPPSPPPPLPSNASSEIEFPLPPPPPLMMLPEKNVFPPSLSTEKIQAEFENFPGLPLPPPPEDEKFERECLSTFPPPPPPPPAPALKPAHLLSSSVQEKHNGTFIQYSQEEASSSQAKITTGKSGGRLPPPTLPKPKFPKQIEDIKNHSSPKVDLENSLPDTECKMTPSKDQKRVITATSSEHIETMQNVSSKSLDKRKQLSMDSTRSFSQAVPESSPPKKKPIAPLIKSHSFPAGSGQQSPKPYMRKFKTPLMIAEEKYRQQREELEKQRQGSSGYNIVRTESQNQNISELKKEVLLQKTKEEVPLTGMDSEVTAAQTNPVSQSLSQDLRVCTDNQLSTTPAVTFSAKRLQHVPATLEGKDTMKKEVLQSSKGMIQSKSACEIKQSQQEYRTQQTQQKHLEQLHLPKSQPVSPSFKVKTMKVPILGHKLDETNHSYESHKKQSEVDIQTITKQQYQETGRTEARTEGSSYKHSVTEKHYQLPAKEKRATIQLPTETTGKSHESKLKIVHEKQREFRESESGKFLGSEETIQGPPMIGPKKESLIAETKQEHLNISAQKVVEQKVTEAHLDSQTQNFQQTHTQSFESQVEHKKLPQPNNNLQEEKYLGVKGIQQKQVFSNTKESKQEITQNKSLFSSAKESQQDDGKRAVNVLEFLRKREELQQILSRVKEFEAEPDKNGLKTFQMLLKIIPVWLLSEEKREYGVHIAMENNIEKIKEEITHIKTQAEDMLVSCENTIQTAMISSKAGKQRNKATSLNETLSKVSNANVSYNKNTQQKENTIVEKAEHHQVATHQETTAHHQVKTHQEIKLDDAKVPPPSLKTRPSSPTFITIESTARRTQTSPKDELSQSPKKDSFAELSPRPSQPTRILKANTSPSPPKSRSEQLVKLKDTTAKLSRGIIPCSSITPVPIVEKRSEIITSPATLRRQIKIEARGRDSPPTITIPITVNHADSGSFKESMEAQEEVRKVENRSTYVHKDGVNSATDIVPDTECFDAVEIIRKVEGPRLSEHAQRYEAANRTVEMAENFMSDHEHEINRWFRGFEDGLSFDTQSNRRAYINGEANRNIKQESRSFKEEFGLTSSESTSFTGFSHSRPRELQEMMPVKLPSIRSETRSLSEHFSGVDAFESQVVGSKTTVSSSHGSEAGRSRFDFKHAPPTYEDVIAGHILDVSDSPKELRRNFQQTWQESERVIKNSGYATSDASATEMETTFQEESAFIRETATPRQGNMHTLSKDGLSNGVPSSRQAEFS", "length": 3561, "header": "tr|E1BL04-1|E1BL04_BOVIN Isoform 1 of Xin actin binding repeat containing 2 OS=Bos taurus OX=9913 GN=XIRP2 PE=3 SV=4 CANONICAL=E1BL04-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SUE1-1", "url": "https://www.uniprot.org/uniprotkb/E1BL04/entry#A0AAA9SUE1-1", "sequence": { "sequence": "MLELKLVLRTICLVCVPHTVLHKDNLESSMFPMQKGSLNLLRQKWESSDYQKSEYSPRGSRCRLFQPQENKLLEPEGEVASTPGPPDPPSLLRSVREEILSVEPEEKCPEDKSDYSRDYGQLEVLKEDSLSGRHRIERFSIALDELRSVFEAPRSGNRQAGPAEYSRKEVEIERNLCSPTFKSHPGSQSDDSVKDSGKKDKETPYDKISSESGHSHIVEVTTGPIKPASGFAEDTAVQSKSASDLQEVVSLKERMAKYQAAVSRGDCRSFSANMLEESEMCTVPGGLARVKKQFEKDKIASSSNTFTQYQYQHQNRSEQEVIRSSQVDISRCSQEMERNEPEISEAHKIDVLGTEMVSHLEKHTEEINQASKLHQYVQETVIDTPEDEEIPKVSTKFLKEQFEKSVQEKVLYSDKELTPAKQIKKLQLQDKEICILCQKTVYPMECLVADRQSFHKSCFRCHHCNSKLSLGNYASLHGQIYCKPHFKQLFKSKGNYDEGFGHKQHKDRWKCKNQSSSVDFTPNEDPNMCKNNVENTPMLGELNKHLDADNSEGQRDGLKKCGKRGKLKIIWPPSREIPKKTFPLEEELKMSKPKWPPEMTTPTSAEFKSGSLIEHMKTVENKGQERDNISCLQSIHMCQKEDVTGIKEMEAYEARKEKKEGNKDVQDKVNEAEDTKKKRKSEMDLNDNNNAVVQSAEKEKNEKANESDGAEVLQVTNTDDEVVPENRKENLNKNNNNNYVAASYLNNCRQKTSVLEFPNLLPLSSEVYYTANEYQIENLENASKLSELLGIFESEKTDSRNVLPMTLDKQTDGATAGSPVQSVSRSGLGDGKSSMPSSETNILNIKGNHSNNKNLHFFFSNTVKIAAFSKRNENIFMHNLIDSVDHIKNMPCLYLRELGKDIKHWHGQTIGAAHVTDLDALSCEFTAKPPFPRVEVQSEQLTVEEQIKRNRHYSDTE", "length": 957, "header": "tr|A0AAA9SUE1-1|E1BL04_BOVIN Computationally mapped isoform of Xin actin binding repeat containing 2 OS=Bos taurus OX=9913 GN=XIRP2 PE=3 SV=1 CANONICAL=E1BL04-1" }, "locus": { "chromosome": "2", "start_pos": 29678708, "end_pos": 28989025, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114466.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114466.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090066.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090066.1" } ] } }, { "isoform_ac": "A0AAA9SWG7-1", "url": "https://www.uniprot.org/uniprotkb/E1BL04/entry#A0AAA9SWG7-1", "sequence": { "sequence": "MADNLESSMFPMQKGSLNLLRQKWESSDYQKSEYSPRGSRCRLFQPQENKLLEPEGEVASTPGPPDPPSLLRSVREEILSVEPEEKCPEDKSDYSRDYGQLEVLKEDSLSGRHRIERFSIALDELRSVFEAPRSGNRQAGPAEYSRKEVEIERNLCSPTFKSHPGSQSDDSVKDSGKKDKETPYDKISSESGHSHIVEVTTGPIKPASGFAEDTAVQSKSASDLQEVVSLKERMAKYQAAVSRGDCRSFSANMLEESEMCTVPGGLARVKKQFEKDKIASSSNTFTQYQYQHQNRSEQEVIRSSQVDISRCSQEMERNEPEISEAHKIDVLGTEMVSHLEKHTEEINQASKLHQYVQETVIDTPEDEEIPKVSTKFLKEQFEKSVQEKVLYSDKELTPAKQIKKLQLQDKEICILCQKTVYPMECLVADRQSFHKSCFRCHHCNSKLSLGNYASLHGQIYCKPHFKQLFKSKGNYDEGFGHKQHKDRWKCKNQSSSVDFTPNEDPNMCKNNVENTPMLGELNKHLDADNSEGQRDGLKKCGKRGKLKIIWPPSREIPKKTFPLEEELKMSKPKWPPEMTTPTSAEFKSGSLIEHMKTVENKGQERDNISCLQSIHMCQKEDVTGIKEMEAYEARKEKKEGNKDVQDKVNEAEDTKKKRKSEMDLNDNNNAVVQSAEKEKNEKANESDGAEVLQVTNTDDEVVPENRKENLNKNNNNNYVAASYLNNCRQKTSVLEFPNLLPLSSEVYYTANEYQIENLENASKLSELLGIFESEKTDSRNVLPMTLDKQTDGATAGSPVQSVSRSGLGDGKSSMPSSETNILNIKGNHSNNKNLHFFFSNTVKIAAFSKRNENIFMHNLIDSVDHIKNMPCLYLRELGKDIKHWHGQTIGAAHVTDLDALSCEFTAKPPFPRVEVQSEQLTVEEQIKRNRHYSDTE", "length": 936, "header": "tr|A0AAA9SWG7-1|E1BL04_BOVIN Computationally mapped isoform of Xin actin binding repeat containing 2 OS=Bos taurus OX=9913 GN=XIRP2 PE=3 SV=1 CANONICAL=E1BL04-1" }, "locus": { "chromosome": "2", "start_pos": 29349480, "end_pos": 28989025, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096867.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096867.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090822.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090822.1" } ] } }, { "isoform_ac": "E1BL04-1", "url": "https://www.uniprot.org/uniprotkb/E1BL04/entry#E1BL04-1", "sequence": { "sequence": "MLELKLVLRTICLVCVPHTVLHKDNLESSMFPMQKGSLNLLRQKWESSDYQKSEYSPRGSRCRLFQPQENKLLEPEGEVASTPGPPDPPSLLRSVREEILSVEPEEKCPEDKSDYSRDYGQLEVLKEDSLSGRHRIERFSIALDELRSVFEAPRSGNRQAGPAEYSRKEVEIERNLCSPTFKSHPGSQSDDSVKDSGKKDKETPYDKISSESGHSHIVEVTTGPIKPASGFAEDTAVQSKSASDLQEVVSLKERMAKYQAAVSRGDCRSFSANMLEESEMCTVPGGLARVKKQFEKDKIASSSNTFTQYQYQHQNRSEQEVIRSSQVDISRCSQEMERNEPEISEAHKIDVLGTEMVSHLEKHTEEINQASKLHQYVQETVIDTPEDEEIPKVSTKFLKEQFEKSVQEKVLYSDKELTPAKQIKMESESEETLKPSSIVGTSSTSYTSTSQRKETSTTRYSDHSATSSTLAQINATPSEKTEEFPPPPPDMLQPPVDVTAFSQSPELPNPPRKPPVPKELYSKQRNLYELNRLYKHIHPELRKNLEKDYISEVSEIVSRQMNAGSSVSADVQQARYVFENTNDSSQKGLNSEREHVEWDEILKGEVQSMRWIFENQPLDSINNGSPDEDNISKGIADQEIIAGGDVKYTTWMFETQPIDTLGDHSSGTEKHAEKIPELARGDVHTARWMFETKPLDSMNKLHQSQEESIATAIKDITGGDVKTVRYMFETQHLDQLGQLHSVDEMHLLQLRSELKEIKGNVKRSIKYFETQPLYVIRDGSGQMLEIKTVHREDVEKGDVRTARWMFETQPLDTINKDITEIKVVRGISMEENVKGGVHRAKWLFETQPLEKIKEETEEVIVEKETVIGTDVSKKCWMFETQPLDILKEVPDADHLKSEEIIGGDVQTTKQLFETLPIEALKDSPDVGKLQKITASEEEKGDVRHQKWIFETQPLEEIREDKKEYIRTVKLEEVDRGDVRNYTHIFESNNLIKFDASHKIEVEGVTRGAVELNKSLFETTPLYAIQDHLGKYHQVKTVQQEEILRGDVRSCRWLFETRPIDQFDESIHKYQIIRGISAQEIQTGNVKSAKWLFETQPLDSIKHFSNMEEVERKTEQVTDIVKGDVKTCRWLFETQPMESLYEKVSLMTGSKEIHKGDVKACTWLFETQPLDTIKDDSEATVKLQTVKQEEIHGGDVRTTCFLFETENLDSIQGEEGKEIKAIEMDIQAGDVSSMRHKFESQSLDSISSGSEEVLRKIKTLKAEDIQKGNVLNCRWLFENQPIDMIKESQEGDELVKTVTDIQGGNVRKGCFIFETFSLDEIKEESDYISTKKTITEEVIKGDVKSYRMLFETQPLYAIQDREGFYHEVTTVKKEEVIHGDVRGTRWLFETKPLDSINESETVYVIKSVTQEDIQKGDVSSVRYRFETQPLDQIAKESRDIVPTVDCIQGGDVRKSKQFFESENLDKNTYVRTVSVNEIQKGNVKTSTWLFETHTLDELRGEGSEYENIKTVTQEDMQKGDVKQAVWLFENQTLDSIKEADESITKITKEEIPPADVKTTTWLFETTPLHRFTENRVEKVEIIGKSIKETLGELYSQKVIEAPGIIIEADEVGDVRMAKYKLMNQASPEIQKEEIIKVDLRNIMVNLLSKRDCKKREILVSEEEKGNVNLTKTQLLNRSTEFHAEKEEIVSGDVQQAIKNLFSEERSVKKGILIQEDERGDINMTIYCLLHENAGDTIKREEIVGGDVKRTIHNLLSSISNNKISERAKIDASERGNVQFFTTCIETGALDYLRQLQTGSNEILTGRKQEKEEEIIGGDVEGTKLLLKKRQSQVERTVNETDIIPGDVRNTVKVFLTEPQNTSCKLPKEEIIKGDVKSTLNSLSQAVSQKTVAKTEEIIKGDMLTTLKSLKESSQKWKDSKQPDVVPGDIEKAIECLEKTARTRTEILKKELILDDLEASLRNLKETQTAFKEVNKSAVKDEVQTVMAGSKEEQKTGTHQVAVQRDKKSILQPRPGPFEPAARWQEGADILNQTINKSCHGDLMKERTEVNLPKAPKGPVKIVIDREQNNDALEKNLRKLSNSHQVGIWTDNMTEQHLRDEHVSGQLTSTLSVREHRKTKEAETEREQKKEAVFLQSIDKTIGKQQTETGQLRNDYQKIEAFPVKSPKNTKNTKTSTDTQSSRPGLTQGPVNRMVGETREVSEDFQKQTLLKQEKQYSNKDIMKKNVTLQPGWQTLPVNQDMSNVTEVKVSQKSHNQLKAIDKKQTDIHLKSQDFLMKTNTSKDLKMAMEMSFNPIKFNPENNAKENEFPLPPPSPPPPLPSNASSEIEFPLPPPPPLMMLPEKNVFPPSLSTEKIQAEFENFPGLPLPPPPEDEKFERECLSTFPPPPPPPPAPALKPAHLLSSSVQEKHNGTFIQYSQEEASSSQAKITTGKSGGRLPPPTLPKPKFPKQIEDIKNHSSPKVDLENSLPDTECKMTPSKDQKRVITATSSEHIETMQNVSSKSLDKRKQLSMDSTRSFSQAVPESSPPKKKPIAPLIKSHSFPAGSGQQSPKPYMRKFKTPLMIAEEKYRQQREELEKQRQGSSGYNIVRTESQNQNISELKKEVLLQKTKEEVPLTGMDSEVTAAQTNPVSQSLSQDLRVCTDNQLSTTPAVTFSAKRLQHVPATLEGKDTMKKEVLQSSKGMIQSKSACEIKQSQQEYRTQQTQQKHLEQLHLPKSQPVSPSFKVKTMKVPILGHKLDETNHSYESHKKQSEVDIQTITKQQYQETGRTEARTEGSSYKHSVTEKHYQLPAKEKRATIQLPTETTGKSHESKLKIVHEKQREFRESESGKFLGSEETIQGPPMIGPKKESLIAETKQEHLNISAQKVVEQKVTEAHLDSQTQNFQQTHTQSFESQVEHKKLPQPNNNLQEEKYLGVKGIQQKQVFSNTKESKQEITQNKSLFSSAKESQQDDGKRAVNVLEFLRKREELQQILSRVKEFEAEPDKNGLKTFQMLLKIIPVWLLSEEKREYGVHIAMENNIEKIKEEITHIKTQAEDMLVSCENTIQTAMISSKAGKQRNKATSLNETLSKVSNANVSYNKNTQQKENTIVEKAEHHQVATHQETTAHHQVKTHQEIKLDDAKVPPPSLKTRPSSPTFITIESTARRTQTSPKDELSQSPKKDSFAELSPRPSQPTRILKANTSPSPPKSRSEQLVKLKDTTAKLSRGIIPCSSITPVPIVEKRSEIITSPATLRRQIKIEARGRDSPPTITIPITVNHADSGSFKESMEAQEEVRKVENRSTYVHKDGVNSATDIVPDTECFDAVEIIRKVEGPRLSEHAQRYEAANRTVEMAENFMSDHEHEINRWFRGFEDGLSFDTQSNRRAYINGEANRNIKQESRSFKEEFGLTSSESTSFTGFSHSRPRELQEMMPVKLPSIRSETRSLSEHFSGVDAFESQVVGSKTTVSSSHGSEAGRSRFDFKHAPPTYEDVIAGHILDVSDSPKELRRNFQQTWQESERVIKNSGYATSDASATEMETTFQEESAFIRETATPRQGNMHTLSKDGLSNGVPSSRQAEFS", "length": 3561, "header": "tr|E1BL04-1|E1BL04_BOVIN Isoform 1 of Xin actin binding repeat containing 2 OS=Bos taurus OX=9913 GN=XIRP2 PE=3 SV=4 CANONICAL=E1BL04-1" }, "locus": { "chromosome": "2", "start_pos": 29678708, "end_pos": 28995196, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023600.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023600.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023600.7", "url": "https://www.ensembl.org/id/ENSBTAP00000023600.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" }, { "name": "alpha-actinin binding", "id": "GO:0051393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051393", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" }, { "name": "positive regulation of protein localization", "id": "GO:1903829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903829", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" }, { "name": "regulation of actin filament organization", "id": "GO:0110053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110053", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "E1BL04", "url": "https://www.uniprot.org/uniprotkb/E1BL04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1012, "end_pos": 1014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1396, "end_pos": 1398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1529, "end_pos": 1531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1667, "end_pos": 1669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1675, "end_pos": 1677, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1721, "end_pos": 1723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1837, "end_pos": 1839, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1859, "end_pos": 1861, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1973, "end_pos": 1975, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2030, "end_pos": 2032, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2034, "end_pos": 2036, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2090, "end_pos": 2092, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2224, "end_pos": 2226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2242, "end_pos": 2244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2278, "end_pos": 2280, "annotation": "n_glycosylation_sequon" 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"annotation": "n_glycosylation_sequon" }, { "start_pos": 3329, "end_pos": 3331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 980, "end_pos": 982, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK69-1", "uniprot_ac": "E1BK69", "uniprot_id": "E1BK69_BOVIN", "mass": { "chemical_mass": 53137.0, "monoisotopic_mass": 53137.0 }, "refseq": { "ac": "NP_001069945", "name": "ufm1-specific protease 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069945" }, "gene_names": [ { "name": "UFSP2", "type": "recommended", "evidence": [ { "id": "E1BK69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK69" } ] }, { "name": "UFSP2", "type": "synonym", "evidence": [ { "id": "NP_001069945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069945" } ] } ], "protein_names": [ { "name": "Ufm1-specific protease 2", "type": "recommended", "evidence": [ { "id": "E1BK69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK69/entry#names_and_taxonomy" } ] }, { "name": "ufm1-specific protease 2", "type": "synonym", "evidence": [ { "id": "NP_001069945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069945" } ] } ], "function": [ { "annotation": "Thiol-dependent isopeptidase that specifically cleaves UFM1, a ubiquitin-like modifier protein, from conjugated proteins, such as CD274/PD-L1, CYB5R3, DDRGK1, MRE11, RPL26/uL24, TRIP4 and RPL26/uL24. While it is also able to mediate the processing of UFM1 precursors, a prerequisite for conjugation reactions, UFSP2 mainly acts as a protein deUFMylase that mediates deconjugation of UFM1 from target proteins. Mediates deUFMylation of RPL26/uL24, a critical step to release the UFM1 ribosome E3 ligase (UREL) complex during the recycling of 60S ribosome subunits from the endoplasmic reticulum. Catalyzes deUFMylation of TRIP4, regulating intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation.", "evidence": [ { "database": "UniProtKB", "id": "E1BK69", "url": "https://www.uniprot.org/uniprotkb/E1BK69#function" }, { "database": "UniProtKB", "id": "ARBA00056184", "url": "https://www.uniprot.org/uniprotkb/ARBA00056184#function" }, { "database": "UniProtKB", "id": "A0AAA9SV87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV87#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK69", "url": "https://www.uniprot.org/uniprotkb/E1BK69" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UFSP2", "url": "https://www.uniprot.org/uniprotkb/E1BK69", "locus": { "chromosome": "27", "start_pos": 15654118, "end_pos": 15673604, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018454", "url": "https://www.ensembl.org/id/ENSBTAG00000018454" } ] } } ], "crossref": [ { "id": "E1BK69", "url": "https://alphafold.ebi.ac.uk/entry/E1BK69", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018454", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018454", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617788", "url": "https://www.ncbi.nlm.nih.gov/gene/617788", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617788", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617788", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDILFRV", "url": "https://omabrowser.org/oma/group/MDILFRV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BK69", "url": "https://www.orthodb.org/?gene=E1BK69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48153:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48153:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07910", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07910", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069945", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069945", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SV87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SV87-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK69", "url": "https://www.uniprot.org/uniprotkb/E1BK69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK69-1", "url": "https://www.uniprot.org/uniprotkb/E1BK69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVISEAMDILFRIRGGLDLAFQLATPNEIFIKNALKHVLSDLSTKLSSNALVFRICHSSVYVWPNSDMNTIPGELTDSSACKDIMRFIQFEQEEDTKRKFTKKKDKKLSDMHQIVNIDLMLEVSTPLAAVTPIIERESGGHHYVSMTLPVDAVLSVAPEETWGKVRKLLVDAIHNQLTDMEKCILKYMKGTSIVVPEPLHFSLPGEKNLVTISYPSGIPDGQLQAYRKELHDVFNLPHDRPYFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNIETGMVYVVQGTYGYHHYMQDRIDDNGWGCAYRSLQTICSWFKHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNHLIGVTSKILFVSQGSEMASQGRELANHFQSEGTPIMIGGGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPEFWNKDAYYNLCLPQRPNTI", "length": 469, "header": "tr|E1BK69-1|E1BK69_BOVIN Isoform 1 of Ufm1-specific protease 2 OS=Bos taurus OX=9913 GN=UFSP2 PE=3 SV=1 CANONICAL=E1BK69-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SV87-1", "url": "https://www.uniprot.org/uniprotkb/E1BK69/entry#A0AAA9SV87-1", "sequence": { "sequence": "MVISEAMDILFRIRGGLDLAFQLATPNEIFIKNALKHVLSDLSTKLSSNALVFRICHSSVYVWPNSDMNTIPGELTDSSACKDIMRFIQFEQEEDTKRKFTKKKDKKLSDMHQIVNIDLMLEVSTPLAAVTPIIERESGGHHYVSMTLPVDAVLSVAPEETWGKVRKLLVDAIHNQLTDMEKCILKYMKGTSIVVPEPLHFSLPGEKNLVTISYPSGIPDGQLQAYRKELHDVFNLPHDRPYFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNIETGMVYVVQGTYGYHHYMQDRIDDNGWGCAYRSLQTICSWFKHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNHLIGVTSKILFVSQGSEMASQGRELANHFQSEGTPIMIGGGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKVSVCLTNKYKEKNPKPGGRTGS", "length": 463, "header": "tr|A0AAA9SV87-1|E1BK69_BOVIN Computationally mapped isoform of Ufm1-specific protease 2 OS=Bos taurus OX=9913 GN=UFSP2 PE=3 SV=1 CANONICAL=E1BK69-1" }, "locus": { "chromosome": "27", "start_pos": 15673538, "end_pos": 15657461, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123432.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123432.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088098.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088098.1" } ] } }, { "isoform_ac": "E1BK69-1", "url": "https://www.uniprot.org/uniprotkb/E1BK69/entry#E1BK69-1", "sequence": { "sequence": "MVISEAMDILFRIRGGLDLAFQLATPNEIFIKNALKHVLSDLSTKLSSNALVFRICHSSVYVWPNSDMNTIPGELTDSSACKDIMRFIQFEQEEDTKRKFTKKKDKKLSDMHQIVNIDLMLEVSTPLAAVTPIIERESGGHHYVSMTLPVDAVLSVAPEETWGKVRKLLVDAIHNQLTDMEKCILKYMKGTSIVVPEPLHFSLPGEKNLVTISYPSGIPDGQLQAYRKELHDVFNLPHDRPYFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNIETGMVYVVQGTYGYHHYMQDRIDDNGWGCAYRSLQTICSWFKHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNHLIGVTSKILFVSQGSEMASQGRELANHFQSEGTPIMIGGGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPEFWNKDAYYNLCLPQRPNTI", "length": 469, "header": "tr|E1BK69-1|E1BK69_BOVIN Isoform 1 of Ufm1-specific protease 2 OS=Bos taurus OX=9913 GN=UFSP2 PE=3 SV=1 CANONICAL=E1BK69-1" }, "locus": { "chromosome": "27", "start_pos": 15673538, "end_pos": 15654198, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024562.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024562.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024562.4", "url": "https://www.ensembl.org/id/ENSBTAP00000024562.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617788", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617788", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XT68-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "UFSP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRPGPAPAAALTDVVILEAMDILFRIRGGLDLAFQLATTDEASAKSALKYVFSDLANKLSSDVLVLRICNSSVYVWPNNGINTVPELTDDSACKEIKRFIHFDQDDETRRKLGKKKDKKLQDMPQVINIDLMLEMTSSSDALAPVIERENKEHHYINMTLPVDVVVSVSPDETWGKVQNLLVKAIHKQLTDMERCIMKYMKGTSIVVPEQFHFMLPGKNHLVTISYPTGISDDQLESYRKELHGLFNLPCDRPYFKRANAYHFPDEPYKDGYLRNPHLHLNSPGPESGVVYLVHGTYSYHHYMQDRTDDSGWGCAYRSLQTICSWFKQQGYVDAPIPTHKEIQQALVDAGDKPAAFVGSRQWIGSVEVQLVLNQLFGITSKILFVSQGSELALQGRELANHFKTEGTPVMIGGGVLAHTILGVAWNEMTGQIKYLILDPHYTGGEDLHVILDKGWCAWKGPDFWSKDAYYNLCLPQRPKTI", "length": 481 }, "evidence": [ { "id": "E1BK69", "url": "https://omabrowser.org/oma/group/E1BK69/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7F3I7-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "Ufsp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVDVRHSGSCSPSAGALSSSGLDATSGPTLACAKSSFLSSPGGEPEMFIKNALRQVLNDLTTKLSSDALVFRVSNSSMYLWPNSDTNTGELTDSSTCKNIVHLIQFEQEEDKKRKFTKKKDKKSSDMQQIVNIDLMLEISTSLGAVTPIIERENEEHHYINMNLPIDVVVAVAPEETWGKVRKLLVDAVHNQLVDVEKCILRYIKGTSIVVPEPLHFLLPGEKNLVTVLYPSGIPDAQLQAYRKELHDLFNLPHDRPYFKRANAYHFPDEPYKDGCIRNPHAYLSPPNIEGSVMCVVQGIYAYHHYMQDRIDDNGWGCAYRSLQTICSWFRHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNQLIGVTSRILFVSQGSEMTSQGRELANHFQNVGTPVMIGGGVLAHTILGVTWNETTGQIKFLILDPHYTGAEDLQVILEKGWCGWKSPDFWNKDAYYNLCLPQRPNAV", "length": 485 }, "evidence": [ { "id": "E1BK69", "url": "https://omabrowser.org/oma/group/E1BK69/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1RZQ3-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "UFSP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVISETMDILFRIRGGLDLAFQLATPNEIFVKKALKHVLSDLSTKLSSNALVFRICHSSVYIWPNSDMNTIPGELTDSSACKNIMRFIQFEQEEDTKRKFMRKREKKLSDLHQIVNIDLMLEMSTPLAAVTPIIERESGGHHYVNMTLPVDAVISVAPEETWGKVRKLLVDAIHNQLTDMEKCILKYIKGTSIVVPEPLHFLLPGGKNLVTISYPSGIPDGQLQDYRKELHDLFNLPHDRPCFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNIETGMIYVVQGTYGYHHYMQDRVDDNGWGCAYRSLQTICSWFKHQGYTERPIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNHLIGITSKILFVSQGSEMASQGRELANHFQTEGTPVMIGGGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYYNLCLPQRPNII", "length": 469 }, "evidence": [ { "id": "E1BK69", "url": "https://omabrowser.org/oma/group/E1BK69/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5XIB4-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "Ufsp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDILFRIRGGFDLAFQLAPPKEMFIKNALRQVLNDLTTKLSSDALVFRICNSSVYLWPNSDANTGELTDSSACKSVVDLIQFDQEEDTKRKFMKKKDKKLTDMQQIVNIDLMLEISTPLGAVTPIIERENEEHHYINMSLPIDAVVSVAPEETWGKVRKLLVDAILNQLVDVEKCILRYMKGTSIVVPEPLHFLLPGGKNLVTVLYPSGIPDDQLQAYRKELHDLFKLPHDRPYLKRINAYHFPDELYKDGYIRNPHAYLSPPNIEGSMICMVQGTYAYHHYMQNRVDDNGWGCAYRSLQTVCSWFRHQGYTERAIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNQLIGVTSKILFVNQGSEMASQGRELANHFQNVGTPVMIGGGVLAHTILGVAWNETTGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYYNLCLPQRPNAL", "length": 461 }, "evidence": [ { "id": "E1BK69", "url": "https://omabrowser.org/oma/group/E1BK69/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7T347-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "ufsp2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGFQSSVEGLTQASACGDILQYIESDDGGNKKSSKKKDKKKSGPIVVNLKLLFEVTDPAGNEAPSLMRMSAQQHSVKMPLPLDCVLSVSADESMTTVFTGLVEALNKQIADMEEVVLRYRKGSSFLVPQPFHFQLPKPAGLTTVIYPAGVPDSQLQAVREDLHRKFELSLDRPYLRRANAFHFPYEAYKDGYLRNPHIHLNPPNIEDAKLYLVQGVYSYHHYMQDRVDDDGWGCAYRSLQTICSWFQQQGYVETAVPTHTQIQQALVDVGDKEPRFVGSRQWIGSIEVQAVLNQLLGVTSKIMFVSQGSELATKGRELANHFHTEGTPVMIGGGVLAHTILGVAWSENTGEIRFLILDPHYTGGEDLQIITDKGWCGWKGPEFWDQNAYYNLCLPQRPKTV", "length": 401 }, "evidence": [ { "id": "E1BK69", "url": "https://omabrowser.org/oma/group/E1BK69/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q99K23-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "Ufsp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDILFRIRGGFDLAFQLAPPKEMFIKNALRQVLSDLTTKLSSDALVLRVCNSSVYLWPNSDANTGELTDSSACKNVVRFIQFDQEEDTKRKFIKKKDKKLTDTQQIVNIDLMLEISTPLGAVTPILERENEEHHYINMSLPIDAVVSVAPEESWGKVRKLLVDAILRQLVDVEKCILRYMKGTSIVVPEPLHFQLPGKKNLVTVLYPSGIPDDQLQAYRKELHDLFNLPHDRPYFKRINAYHFPDELYKDGYIRNPHTYLSPPNIEGSMICVVQGTYAYHHYMQDRIDDNGWGCAYRSLQTICSWFRHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQMVLNQLIGVTSKILFVNQGSEMASQGRELANHFQNVGTPVMVGGGVLAHTILGVAWNETTGQIKFLILDPHYTGAEDLQVMLEKGWCGWKSPDFWNKDAYYNLCLPQRPNAL", "length": 461 }, "evidence": [ { "id": "E1BK69", "url": "https://omabrowser.org/oma/group/E1BK69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUQ7-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "UFSP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVISESMDILFRIRGGLDLAFQLATPNEIFLKKALKHVLSDLSTKLSSNALVFRICHSSVYIWPSSDINTIPGELTDASACKNILRFIQFEPEEDIKRKFMRKKDKKLSDMHQIVNIDLMLEMSTSLAAVTPIIERESGGHHYVNMTLPVDAVISVAPEETWGKVRKLLVDAIHNQLTDMEKCILKYMKGTSIVVPEPLHFLLPGKKNLVTISYPSGIPDGQLQAYRKELHDLFNLPHDRPYFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNMETGMIYVVQGIYGYHHYMQDRIDDNGWGCAYRSLQTICSWFKHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNQLIGITSKILFVSQGSEIASQGRELANHFQSEGTPVMIGGGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYYNLCLPQRPNMI", "length": 469 }, "evidence": [ { "id": "E1BK69", "url": "https://omabrowser.org/oma/group/E1BK69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "deUFMylase activity", "id": "GO:0071567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071567", "evidence": [ { "database": "UniProtKB", "id": "E1BK69", "url": "https://www.uniprot.org/uniprotkb/E1BK69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BK69", "url": "https://www.uniprot.org/uniprotkb/E1BK69" } ], "pmid": "" }, { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "E1BK69", "url": "https://www.uniprot.org/uniprotkb/E1BK69" } ], "pmid": "" }, { "name": "negative regulation of proteolysis involved in protein catabolic process", "id": "GO:1903051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903051", "evidence": [ { "database": "UniProtKB", "id": "E1BK69", "url": "https://www.uniprot.org/uniprotkb/E1BK69" } ], "pmid": "" }, { "name": "regulation of intracellular estrogen receptor signaling pathway", "id": "GO:0033146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033146", "evidence": [ { "database": "UniProtKB", "id": "E1BK69", "url": "https://www.uniprot.org/uniprotkb/E1BK69" } ], "pmid": "" }, { "name": "regulation of type II interferon production", "id": "GO:0032649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032649", "evidence": [ { "database": "UniProtKB", "id": "E1BK69", "url": "https://www.uniprot.org/uniprotkb/E1BK69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BK69", "url": "https://www.uniprot.org/uniprotkb/E1BK69" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BK69", "url": "https://www.uniprot.org/uniprotkb/E1BK69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BK69-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 469, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BK69-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BK69" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BK69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK69" }, { "id": "PF07910", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07910" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UFSP1/2/DUB catalytic", "eco_id": "ECO_0000259", "start_pos": 278, "end_pos": 461, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BK69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK69" }, { "id": "PF20908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UFSP2 second", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 256, "start_aa": "His", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEP0-1", "uniprot_ac": "E1BEP0", "uniprot_id": "E1BEP0_BOVIN", "mass": { "chemical_mass": 88925.0, "monoisotopic_mass": 88925.0 }, "refseq": { "ac": "NP_001192662", "name": "protein-lysine N-methyltransferase SMYD4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192662" }, "gene_names": [ { "name": "SMYD4", "type": "recommended", "evidence": [ { "id": "E1BEP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" } ] }, { "name": "SMYD4", "type": "synonym", "evidence": [ { "id": "NP_001192662", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192662" } ] } ], "protein_names": [ { "name": "Protein-lysine N-methyltransferase SMYD4", "type": "recommended", "evidence": [ { "id": "E1BEP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEP0/entry#names_and_taxonomy" } ] }, { "name": "SET and MYND domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "E1BEP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEP0/entry#names_and_taxonomy" } ] }, { "name": "protein-lysine N-methyltransferase SMYD4", "type": "synonym", "evidence": [ { "id": "NP_001192662", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192662" } ] } ], "function": [ { "annotation": "Protein-lysine N-methyltransferase. Monomethylates PRMT5, modulating its transcriptional activity. May also act as a histone methyltransferase. Plays a critical role in cardiac development. Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRU8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRU8#function" }, { "database": "UniProtKB", "id": "ARBA00093423", "url": "https://www.uniprot.org/uniprotkb/ARBA00093423#function" }, { "database": "UniProtKB", "id": "E1BEP0", "url": "https://www.uniprot.org/uniprotkb/E1BEP0#function" }, { "database": "UniProtKB", "id": "A0AAA9SZC4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZC4#function" }, { "database": "UniProtKB", "id": "A0AAA9T3Z3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3Z3#function" }, { "database": "UniProtKB", "id": "A0AAA9T6Z2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6Z2#function" }, { "database": "UniProtKB", "id": "A0AAA9U117", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U117#function" }, { "database": "UniProtKB", "id": "A0AAA9U1U7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1U7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEP0", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SMYD4", "url": "https://www.uniprot.org/uniprotkb/E1BEP0", "locus": { "chromosome": "19", "start_pos": 22845777, "end_pos": 22900285, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009708", "url": "https://www.ensembl.org/id/ENSBTAG00000009708" } ] } } ], "crossref": [ { "id": "E1BEP0", "url": "https://alphafold.ebi.ac.uk/entry/E1BEP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009708", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009708", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10536", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10536", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512868", "url": "https://www.ncbi.nlm.nih.gov/gene/512868", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512868", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512868", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FDCTCPA", "url": "https://omabrowser.org/oma/group/FDCTCPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEP0", "url": "https://www.orthodb.org/?gene=E1BEP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46165:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46165:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192662", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192662", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "51736", "url": "https://www.rhea-db.org/rhea/51736", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SZC4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZC4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3Z3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6Z2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U117", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U117", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U117-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U117-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1U7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1U7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1U7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRU8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRU8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEP0", "url": "https://www.uniprot.org/uniprotkb/E1BEP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEP0-1", "url": "https://www.uniprot.org/uniprotkb/E1BEP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLPVDEWKSYILQKWSLLPKSIQVTISTAETLHDLFLHSSPLLQPEDEMFLKRLSGGYLVGKDPDASLFYREKGNQKFQAKDYMGAAVLYSKGVSHSGPSSTDISLCYANRSAALFHLGQYEICLKDIVRAQTHGYPERLQPKLLLRKAECLVTLGRPQEASQTVTDLESSFAAKPTLSASQFQILQRTLCRVKVKVQEKENLPEIFPEALTKTFEGVDLREENEQIPGASSSVSLHIDPLKGRYLVATKDILPGELLVKEDAFVSVLNPGEVPLRPRGLESKWDIQVTNGDLHCHRCLRHTLAPVPCDGCSYAKYCSQECMQQAWDRYHSVECSLGALLLTLGVFCHVALRSTLLARFEDVGKVTKKLCGEMSNQGICLPESKNPVQTLKYDLGGEGDKKDKAVETPIPGCDINGKYERNYNAIFHLLPHTENHSPEHKFLCALSVSALCRQLEAAGLQAFTTDLKPTKLKAAEPPVLCAELSVWGVAMLRHMLQLQCNAQAITTIQQTGSKESLITDTRRVRLATALFPVVSLLNHSCSPNTSVSFIGTIATIRASQLIRSGQEILHCYGPHESRMGVAERRQKLRSQYFFDCDCPPCEREKQRPSAGPGRGAFRCHRCRALLQGDDVLSCSGPACMESVSRDLLVSRLQDLQRQVGAAQKHLRNGRLEVAIQLLLGCQSDAESFLSAEHSVVGEIEDALAQAYAALGDWEKSATHLQKSLQVVEVHHGPSSVEMGHELFKLAQVFFNGCAVPEALKTIQKAEKVLLVHYGPWNDEIRELQKMKSCLLDLLPIPVGPKE", "length": 802, "header": "tr|E1BEP0-1|E1BEP0_BOVIN Isoform 1 of Protein-lysine N-methyltransferase SMYD4 OS=Bos taurus OX=9913 GN=SMYD4 PE=4 SV=3 CANONICAL=E1BEP0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SZC4-1", "url": "https://www.uniprot.org/uniprotkb/E1BEP0/entry#A0AAA9SZC4-1", "sequence": { "sequence": "MDLPVDEWKSYILQKWSLLPKSIQVTISTAETLHDLFLHSSPLLQPEDEMFLKRLSGGYLVGKDPDASLFYREKGNQKFQAKDYMGAAVLYSKICLKDIVRAQTHGYPERLQPKLLLRKAECLVTLGRPQEASQTVTDLESSFAAKPTLSASQFQILQRTLCRVKVKVQEKENLPEIFPEALTKTFEGVDLREENEQIPGASSSVSLHIDPLKGRYLVATKDILPGELLVKEDAFVSVLNPGEVPLRPRGLESKWDIQVTNGDLHCHRCLRHTLAPVPCDGCSYAKYCSQECMQQAWDRYHSVECSLGALLLTLGVFCHVALRSTLLARFEDVGKVTKKLCGEMSNQGICLPESKNPVQTLKYDLGGEGDKKDKAVETPIPGCDINGKYERNYNAIFHLLPHTENHSPEHKFLCALSVSALCRQLEAAGLQAFTTDLKPTKLKAAEPPVLCAELSVWGVAMLRHMLQLQCNAQAITTIQQTGSKESLITDTRRVRLATALFPVVSLLNHSCSPNTSVSFIGTIATIRASQLIRSGQEILHCYGPHESRMGVAERRQKLRSQYFFDCDCPPCEREKQRPSAGPGRGAFRCHRCRALLQGDDVLSCSGPACMESVSRDLLVSRLQDLQRQVGAAQKHLRNGRLEVAIQLLLGCQSDAESFLSAEHSVVGEIEDALAQAYAALGDWEKSATHLQKSLQVVEVHHGPSSVEMGHELFKLAQVFFNGGRLAMSEDVFNC", "length": 734, "header": "tr|A0AAA9SZC4-1|E1BEP0_BOVIN Computationally mapped isoform of Protein-lysine N-methyltransferase SMYD4 OS=Bos taurus OX=9913 GN=SMYD4 PE=4 SV=1 CANONICAL=E1BEP0-1" }, "locus": { "chromosome": "19", "start_pos": 22898946, "end_pos": 22863162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093895.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093895.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090770.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090770.1" } ] } }, { "isoform_ac": "A0AAA9T3Z3-1", "url": "https://www.uniprot.org/uniprotkb/E1BEP0/entry#A0AAA9T3Z3-1", "sequence": { "sequence": "MDLPVDEWKSYILQKWSLLPKSIQVTISTAETLHDLFLHSSPLLQPEDEMFLKRLSGGYLVGKDPDASLFYREKGNQKFQAKDYMGAAVLYSKGVSHSGPSSTDISLCYANRSAALFHLGQYEICLKDIVRAQTHGYPERLQPKLLLRKAECLVTLGRPQEASQTVTDLESSFAAKPTLSASQFQILQRTLCRVKVKVQEKENLPEIFPEALTKTFEGVDLREENEQIPGASSSVSLHIDPLKGRYLVATKDILPGELLVKEDAFVSVLNPGEVPLRPRGLESKWDIQVTNGDLHCHRCLRHTLAPVPCDGCSYAKYCSQECMQQAWDRYHSVECSLGALLLTLGVFCHVALRSTLLARFEDVGKVTKKLCGEMSNQGICLPESKNPVQTLKYDLGGEGDKKDKAVETPIPGCDINGKYERNYNAIFHLLPHTENHSPEHKFLCALSVSALCRQLEAAGLQAFTTDLKPTKLKAAEPPVLCAELSVWGVAMLRHMLQLQCNAQAITTIQQTGSKESLITDTRRVRLATALFPVVSLLNHSCSPNTSVSFIGTIATIRASQLIRSGQEILHCYGPHESRMGVAERRQKLRSQYFFDCDCPPCEREKQRPSAGPGRGAFRCHRCRALLQGDDVLSCSGPACMESVSRDLLVSRLQDLQRQVGAAQKHLRNGRLEVAIQLLLGCQSDAESFLSAEHSVVGEIEDALAQAYAALGDWEKSATHLQKSLQVVEVHHGPSSVEMGHELFKLAQVFFNGNDPFLLSC", "length": 760, "header": "tr|A0AAA9T3Z3-1|E1BEP0_BOVIN Computationally mapped isoform of Protein-lysine N-methyltransferase SMYD4 OS=Bos taurus OX=9913 GN=SMYD4 PE=4 SV=1 CANONICAL=E1BEP0-1" }, "locus": { "chromosome": "19", "start_pos": 22898946, "end_pos": 22863457, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133757.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133757.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092510.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092510.1" } ] } }, { "isoform_ac": "A0AAA9T6Z2-1", "url": "https://www.uniprot.org/uniprotkb/E1BEP0/entry#A0AAA9T6Z2-1", "sequence": { "sequence": "MDLPVDEWKSYILQKWSLLPKSIQVTISTAETLHDLFLHSSPLLQPEDEMFLKRLSGGYLVGKDPDASLFYREKGNQKFQAKDYMGAAVLYSKGVSHSGPSSTDISLCYANRSAALFHLGQYEICLKDIVRAQTHGYPERLQPKLLLRKAECLVTLGRPQEASQTVTDLESSFAAKPTLSASQFQILQRTLCRVKVKVQEKENLPEIFPEALTKTFEGVDLREENEQIPGASSSVSLHIDPLKGRYLVATKDILPGELLVKEDAFVSVLNPGEVPLRPRGLESKWDIQVTNGDLHCHRCLRHTLAPVPCDGCSYAKYCSQECMQQAWDRYHSVECSLGALLLTLGVFCHVALRSTLLARFEDVGKVTKKLCGEMSNQGICLPESKNPVQTLKYDLGGEGDKKDKAVETPIPGCDINGKYERNYNAIFHLLPHTENHSPEHKFLCALSVSALCRQLEAAGLQAFTTDLKPTKLKAAEPPVLCAELSVWGVAMLRHMLQLQCNAQAITTIQQTGSKESLITDTRRVRLATALFPVVSLLNHSCSPNTSVSFIGTIATIRASQLIRSGQEILHCYGPHESRMGVAERRQKLRSQYFFDCDCPPCEREKQRPSAGPGRGAFRCHRCRALLQGDDVLSCSGPACMESVSRDLLVSRLQDLQRQVGAAQKHLRNGRLEVAIQLLLGCQSDAESFLSAEHSVVGEIEDALAQAYAALDLPLFAGDWEKSATHLQKSLQVVEVHHGPSSVEMGHELFKLAQVFFNGCAVPEALKTIQKAEKVLLVHYGPWNDEIRELQKMKSCLLDLLPIPVGPKE", "length": 808, "header": "tr|A0AAA9T6Z2-1|E1BEP0_BOVIN Computationally mapped isoform of Protein-lysine N-methyltransferase SMYD4 OS=Bos taurus OX=9913 GN=SMYD4 PE=4 SV=1 CANONICAL=E1BEP0-1" }, "locus": { "chromosome": "19", "start_pos": 22898946, "end_pos": 22862268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115326.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115326.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092366.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092366.1" } ] } }, { "isoform_ac": "A0AAA9U117-1", "url": "https://www.uniprot.org/uniprotkb/E1BEP0/entry#A0AAA9U117-1", "sequence": { "sequence": "MDLPVDEWKSYILQKWSLLPKSIQVTISTAETLHDLFLHSSPLLQPEDEMFLKRLSGGYLVGKDPDASLFYREKGNQKFQAKDYMGAAVLYSKGVSHSGPSSTDISLCYANRSAALFHLGQYEICLKDIVRAQTHGYPERLQPKLLLRKAECLVTLGRPQEASQTVTDLESSFAAKPTLSASQFQILQRTLCRVKVKVQEKENLPEIFPEALTKTFEGVDLREENEQIPGASSSVSLHIDPLKGRYLVATKDILPGELLVKEDAFVSVLNPGEVPLRPRGLESKWDIQVTNGDLHCHRCLRHTLAPVPCDGCSYAKYCSQECMQQAWDRYHSVECSLGALLLTLGVFCHVALRSTLLARFEDVGKVTKKLCGEMSNQGICLPESKNPVQTLKYDLGGEGDKKDKAVETPIPGCDINGKYERNYNAIFHLLPHTENHSPEHKFLCALSVSALCRQLEAAGLQAFTTDLKPTKLKAAEPPVLCAELSVWGVAMLRHMLQLQCNAQAITTIQQTGSKESLITDTRRVRLATALFPVVSLLNHSCSPNTSVSFIGTIATIRASQLIRSGQEILHCYGPHESRMGVAERRQKLRSQYFFDCDCPPCEREKQRPSAGPGRGAFRCHRCRALLQGDDVLSCSGPACMESVSRDLLVSRLQDLQRQVGAAQKHLRNGRLDLPLFAGDWEKSATHLQKSLQVVEVHHGPSSVEMGHELFKLAQVFFNGCAVPEALKTIQKAEKVLLVHYGPWNDEIRELQKMKSCLLDLLPIPVGPKE", "length": 769, "header": "tr|A0AAA9U117-1|E1BEP0_BOVIN Computationally mapped isoform of Protein-lysine N-methyltransferase SMYD4 OS=Bos taurus OX=9913 GN=SMYD4 PE=4 SV=1 CANONICAL=E1BEP0-1" }, "locus": { "chromosome": "19", "start_pos": 22898946, "end_pos": 22862268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118888.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118888.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103416.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103416.1" } ] } }, { "isoform_ac": "A0AAA9U1U7-1", "url": "https://www.uniprot.org/uniprotkb/E1BEP0/entry#A0AAA9U1U7-1", "sequence": { "sequence": "MDLPVDEWKSYILQKWSLLPKSIQVTISTAETLHDLFLHSSPLLQPEDEMFLKRLSGGYLVGKDPDASLFYREKGNQKFQAKDYMGAAVLYSKGVSHSGPSSTDISLCYANRSAALFHLGQYEICLKDIVRAQTHGYPERLQPKLLLRKAECLVTLGRPQEASQTVTDLESSFAAKPTLSASQFQILQRTLCRVKVKVQEKENLPEIFPEALTKTFEGVDLREENEQIPGASSSVSLHIDPLKGRYLVATKDILPGELLVKEDAFVSVLNPGEVPLRPRGLESKWDIQVTNGDLHCHRCLRHTLAPVPCDGCSYAKYCSQECMQQAWDRYHSVECSLGALLLTLGVFCHVALRSTLLARFEDVGKVTKKLCGEMSNQGICLPESKNPVQTLKYDLGGEGDKKDKAVETPIPGCDINGKYERNYNAIFHLLPHTENHSPEHKFLCALSVSALCRQLEAAGLQAFTTDLKPTKLKAAEPPVLCAELSVWGVAMLRHMLQLQCNAQAITTIQQTGSKESLITDTRRVRLATALFPVVSLLNHSCSPNTSVSFIGTIATIRASQLIRSGQEILHCYGPHESRMGVAERRQKLRSQYFFDCDCPPCEREKQRPSAGPGRGAFRCHRCRALLQGDDVLSCSGPACMESVSRDLLVSRLQDLQRQVGAAQKHLRNGRLEVAIQLLLGCQSDAESFLSAEHSVVGEIEDALAQAYAALGDWEKSATHLQKSLQVVEVHHGPSSVEMGHELFKLAQVFFNGYTEKECIDD", "length": 761, "header": "tr|A0AAA9U1U7-1|E1BEP0_BOVIN Computationally mapped isoform of Protein-lysine N-methyltransferase SMYD4 OS=Bos taurus OX=9913 GN=SMYD4 PE=4 SV=1 CANONICAL=E1BEP0-1" }, "locus": { "chromosome": "19", "start_pos": 22898946, "end_pos": 22846031, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132810.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132810.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103854.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103854.1" } ] } }, { "isoform_ac": "A0ABI0NRU8-1", "url": "https://www.uniprot.org/uniprotkb/E1BEP0/entry#A0ABI0NRU8-1", "sequence": { "sequence": "MDLPVDEWKSYILQKWSLLPKSIQVTISTAETLHDLFLHSSPLLQPEDEMFLKRLSGGYLVGKDPDASLFYREKGNQKFQAKDYMGAAVLYSKGVSHSGPSSTDISLCYANRSAALFHLGQYEICLKDIVRAQTHGYPERLQPKLLLRKAECLVTLGRPQEASQTVTDLESSFAAKPTLSASQFQILQRTLCRVKVKVQEKENLPEIFPEALTKTFEGVDLREENEQIPGASSSVSLHIDPLKGRYLVATKDILPGELLVKEDAFVSVLNPGEVPLRPRGLESKWDIQVTNGDLHCHRCLRHTLAPVPCDGCSYAKYCSQECMQQAWDRYHSVECSLGALLLTLGVFCHVALRSTLLARFEDVGKVTKKLCGEMSNQGICLPESKNPVQTLKYDLGGEGDKKDKAVETPIPGCDINGKYERNYNAIFHLLPHTENHSPEHKFLCALSVSALCRQLEAAGLQAFTTDLKPTKLKAAEPPVLCAELSVWGVAMLRHMLQLQCNAQAITTIQQTGSKESLITDTRRVRLATALFPVVSLLNHSCSPNTSVSFIGTIATIRASQLIRSGQEILHCYGPHESRMGVAERRQKLRSQYFFDCDCPPCEREKQRPSAGPGRGAFRCHRCRALLQGDDVLSCSGPACMESVSRDLLVSRLQDLQRQVGAAQKHLRNGRLEVAIQLLLGCQSDAESFLSAEHSVVGEIEDALAQAYAALGDWEKSATHLQKSLQVVEVHHGPSSVEMGHELFKLAQVFFNGGRLAMSEDVFNC", "length": 764, "header": "tr|A0ABI0NRU8-1|A0ABI0NRU8_BOVIN Computationally mapped isoform of Protein-lysine N-methyltransferase SMYD4 OS=Bos taurus OX=9913 GN=SMYD4 PE=4 SV=1 CANONICAL=E1BEP0-1" }, "locus": { "chromosome": "19", "start_pos": 22898946, "end_pos": 22863162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149312.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149312.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106500.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106500.1" } ] } }, { "isoform_ac": "E1BEP0-1", "url": "https://www.uniprot.org/uniprotkb/E1BEP0/entry#E1BEP0-1", "sequence": { "sequence": "MDLPVDEWKSYILQKWSLLPKSIQVTISTAETLHDLFLHSSPLLQPEDEMFLKRLSGGYLVGKDPDASLFYREKGNQKFQAKDYMGAAVLYSKGVSHSGPSSTDISLCYANRSAALFHLGQYEICLKDIVRAQTHGYPERLQPKLLLRKAECLVTLGRPQEASQTVTDLESSFAAKPTLSASQFQILQRTLCRVKVKVQEKENLPEIFPEALTKTFEGVDLREENEQIPGASSSVSLHIDPLKGRYLVATKDILPGELLVKEDAFVSVLNPGEVPLRPRGLESKWDIQVTNGDLHCHRCLRHTLAPVPCDGCSYAKYCSQECMQQAWDRYHSVECSLGALLLTLGVFCHVALRSTLLARFEDVGKVTKKLCGEMSNQGICLPESKNPVQTLKYDLGGEGDKKDKAVETPIPGCDINGKYERNYNAIFHLLPHTENHSPEHKFLCALSVSALCRQLEAAGLQAFTTDLKPTKLKAAEPPVLCAELSVWGVAMLRHMLQLQCNAQAITTIQQTGSKESLITDTRRVRLATALFPVVSLLNHSCSPNTSVSFIGTIATIRASQLIRSGQEILHCYGPHESRMGVAERRQKLRSQYFFDCDCPPCEREKQRPSAGPGRGAFRCHRCRALLQGDDVLSCSGPACMESVSRDLLVSRLQDLQRQVGAAQKHLRNGRLEVAIQLLLGCQSDAESFLSAEHSVVGEIEDALAQAYAALGDWEKSATHLQKSLQVVEVHHGPSSVEMGHELFKLAQVFFNGCAVPEALKTIQKAEKVLLVHYGPWNDEIRELQKMKSCLLDLLPIPVGPKE", "length": 802, "header": "tr|E1BEP0-1|E1BEP0_BOVIN Isoform 1 of Protein-lysine N-methyltransferase SMYD4 OS=Bos taurus OX=9913 GN=SMYD4 PE=4 SV=3 CANONICAL=E1BEP0-1" }, "locus": { "chromosome": "19", "start_pos": 22898946, "end_pos": 22862268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012805.7", "url": "https://www.ensembl.org/id/ENSBTAT00000012805.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012805.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012805.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512868", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512868", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5K1VBK2-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "SMYD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLPVDEWKSYILQKWSLLPKSIQVTISTAEALSDIFLHSSLLLQPEDEMFLKRLSGGYLVGKDPGAPLFYREEGNKKFHEKDYMGATLLYSKGVAHSRPSTEDISLCYANRSAALFHLGQYETCLKDIVRAQSHGYPENLQPKMLLRKAECLVTLGRLQEASQTISDLESNFAATPTLAASQFQILQRTLCRLKRKVQEKETLTETFPALLTKALEDMELREENVHVRGASSSVSLRVDPLKGRSLVATKDILPGELLVKEDAFVSVLNPGEMPPRHEGLESKWDTRVTNGDLYCHRCLKPTLATVPCDGCSYAKYCSQECLQQAWDLYHSVECSLGGLLLTLGVFCHVALRSTLLARFEDVGKVRMTLCGETCNRDVSSPEGKNLAQALSYDLGGEREQRGKTVETSVPGCGIDGKYENNYNAVFHLLPHTENHSPEHKFLCALSVSALGRQLQAAGSQPFTAGLKSSKLEAAEAPVLYPEWNIWGVAMLRHMLQLQCNAQAITAIQQTGSKGSLITEHRQVRLATGLFPVVSLLNHSCSPNASVSFISTVATVRASQPIRKGQEVLHCYGPHESRMGVAERHQKLRSQYFFDCNCPPCEREKQRPSALEPRREAFCCHRCRALLQGDDVLSCGSTSCPASVRRHHLDSRLQDLQQQVGLARKLLRNCKAERAIQLLLGCQHDAESFLSAEHSVVGEIADDLAQAYAALGDWKKSASHLQKSLRVVEVRHGPSSVEMGHELFKLAQIFFNGLAIPEALNTIQRAEKVLLVHYGPWNDEIQELQKMKSCLMDLLPIPMGPSE", "length": 803 }, "evidence": [ { "id": "E1BEP0", "url": "https://omabrowser.org/oma/group/E1BEP0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1AM05-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "SMYD4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALPVEEWRRSAARCWAVLEPALRERLAAAPLGEALRMGCGLFGPEEAALQRLCRRARTGKEPAAARFYREEGNRQFGRCCYRDAVRLYSQAAAHEPPRSPEVALCFANRSAALFHLGHFEVCLEDIARAESHGYPDRLLPKVLLRKAECLLRLGKLQDATDTLTAVENKMTVDGIMTSPIHRMLLKKLSQLKTEIHEGSCPEPAREAHGDIQRESEIWEENGSISGASSSLSLNFSTERGRHLVASQDILPGQNLLKEKAFVSVLCPGEGDSLLLQDSSETVWDTRVTNADLYCHHCLKQLLASIPCCGCSYAKYCSQNCADVAWEQYHRTECPLGALLLTLGVFCHVALRTVLLAGFSEVSRLVEWSRDDSNKDLCNAEAGGEHPSEVLDTRAGRKVIPGCNDNGQYQSSYQAVFNLLPHVEKHSPEHKFLCMLSIVAICKKLQETGLEAAVLNGESSTTGSEQKTCGKTSDELSPELMIMAEAMLRHVLQLQCNAQAITVMQELESGDGAVVNKKPVRLATAFFPVLSLLNHSCSPNISVSFSGTAATVRASQPIPSGQEIFHCYGPHRCRMRVAERQQLLSQYFFECRCQACLDELESDVESVSMRNSFCCPSCQASMQGEEMLCCSNEACAFSVSRERLSQRLLDLQQQMEKALELLRDSKADEAIKMLLKCQIDARNFLSPEHLLMGELEDHLAQVYATLGKWQEAARHLGRSIQLVEMHHGPSSVEMGHELFKLAQILFNGFAVSEALSTIQRAEEILSVHCGPQSTQIQELQEMKTCLLELPRSILQRT", "length": 797 }, "evidence": [ { "id": "E1BEP0", "url": "https://omabrowser.org/oma/group/E1BEP0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4AEC7-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "Smyd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLPVDEWKSYLLEKWALLPKSVQVTISTAETLSDIFLHSSSLLQPEDEMFLKQLSSSCSVEKDSGAPLFYREEGNKRFQEKEYMGAAVLYSKGVSHSRPNTEDISLCYANRSAALFHLGQHEACLKDIVRAGMHGYPERLQPKLMIRKTECLVNLGRLQEARQTISDLENSLTTKPTLMPSSHQILQRNVQQLKMKIQEKETLPESFPAALTKALEDMALGEENKQISGASLSVSLCTDPLKGRHLVATKDILPGELLVKEDAFVSVLNPGEMPPLRHCLENKWDTRVTSADLYCHRCLRHTLATVPCGGCSYAKYCSQECVQQAWDHYHSTECSLGGLLLTLGVFCHVALRMTLLARFEDVDRVIRMICDKTGRKDTCLPESKDLVKTFGYTNQGESEENSETCEPSIPGCNVNGKYENNYDAVLSLLPHTEKHSPEHKFICAVSVSALCRQLKATSLQAQTTGLKSPRLKAVTPGLCTDLTVWGVAMLQHMLQLQCNAQAITSICYAGSKESIITNSRQVRLATGVFPVVSLLNHSCSPNTSVSFTSTVATIRAAQQIAKGQEILHCYGPHESRMGVAERQQRLSSQYFFDCSCPACHAETLRAAVAPRWEAFCCNTCRVPMQGNDVLSCSNESCTNSVSRDRLVSRLQDLQQQVHTAQKLLRSDRPEQAIQQLLECQRAAENFLSAEHTVLGEIEDGLAQAYATLGDWRQSAAHVQKSLQVVEARHGPSSVEIGHELFKLAQVLFNGLAVPEALDAIWKAEKILLVHCGPESDEVQELREMRSCLLDSSFTPVRPLV", "length": 801 }, "evidence": [ { "id": "E1BEP0", "url": "https://omabrowser.org/oma/group/E1BEP0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4HR71-1", "protein_name": "Tetratricopeptide repeat (TPR)-like superfamily protein", "gene_name": "TPR9", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEKLKSLIPEDLLQTVKSSSVDDLLSTSSSLLRLFLGLPQFHQAVSELANPELGCCGKNEETSLDLKRRGNHCFRSRDFDEALRLYSKALRVAPLDAIDGDKSLLASLFLNRANVLHNLGLLKESLRDCHRALRIDPYYAKAWYRRGKLNTLLGNYKDAFRDITVSMSLESSLVGKKQLQNELKAIPDYQNNQTLEHDEYRPSNDAGVDHLPSVQMEVKLRCVSTKEKGRGMVSECDIEEASVIHVEEPFSVVISKSCRETHCHFCLNELPADTVPCPSCSIPVYCSESCQIQSGGMLSTNEMDKHHIFQKLPDDIVEHIKGVTSADIYYFATDLIQEHQHECRGANWPAVLPSDAVLAGRIIMKLINQGKAATDLSNLQEILELSHTYSKMNPENKLELHLLSIVLIWCLSKSSCPNLSVCEASVTQTIILLSQIKVNSIAVARMKSSGDSFKCLPSGNISTKEPIQSLEQIRVGQALYKTGSLFNHSCKPNIHLYFLSRGLIMQTTEFVPTGCPLELSYGPEVGKWDCKNRIRFLEEEYFFHCRCRGCAQINISDLVINGYGCVNTNCTGVVLDSNVATCESEKLNHFFTAPRNVDQQVQMREKVYADVGEVASSLLSKPSGSLHIEPEICLKCGSRCDIENSHAEVNKAWNHMRRVEELMNSGRANYSVLSDCSRSIAVLRTFLHMYNKDIADAEDKVAQACYLAGELVDARKHCEASIKILKRLYEDEHVVIGNEMVKLASIQLASGDSSGAWDTTKRSSQIFSKYYGSHAETLFSYLPCLKQETAKAVNLSTS", "length": 798 }, "evidence": [ { "id": "E1BEP0", "url": "https://omabrowser.org/oma/group/E1BEP0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q08C84-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "smyd4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLPCQDWVCHVEQKWAELRSEETERFSLLTDIDAIFNYGLSLICPEDLNILSRISEKFSVKKSPETASEFRQQGNLSFKVKDYPAAVLHYSKGVCHADKNTDELSLCYANRSAALFYQGLYQACLEDIRRSLEAGYPSHLQDKLQTRQTACQNQLRKAEKPNIPHTDHQLSPCQKTVNSTGHLSDGVSVYFSSDKGRHMLVMENKPAGEVVLEDEAYCSVLIPANIFNTGTNKAVETFGTEDRHCHHCLSQSLSFVPCPKCSYARYCGESCQKDAWDQWHQWECPVGADLLAIGVLGHLALRVVLKAGQTEVQMGIKNTKDHVTTYKNDSPVQLSLGGDCGKSLDHTDCFHGSSYMGIYSLLPHVAQHSPASRFLMAITMAVIYGKLQGGPPPNKWMSFKDEGVKASWQPEMSMLGATALRHMMQLRCNAQAITAVRVKEESGMAVQSSSEIRIATAIFPVLSLLNHSCSPNTSISFTTGFQPDPHNQLGCSEGHFDHPKGSRSGVTVTVRASKDLTAGQEILHCYGPHRSRMEVKERQRLLLEQYFFQCVCQACQRDLSEGSPNAKEHTAPGMKCVKCGKPLQSHTDGYTCSWSSCGHQISSADVQNRLQGFQLLLDEAVHLMEQDRLNEALHILQSAFSQANSILTETHPFQGELADALARLYASTGEWSLAASHLKRSLVAIQAQFGEDSIELGRQLFKLAQLHFNGRDGVASLSVIPRARRLLSLHCSPRCEELQELSEMEHCLQGLL", "length": 753 }, "evidence": [ { "id": "E1BEP0", "url": "https://omabrowser.org/oma/group/E1BEP0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BTK5-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "Smyd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLPVDEWKSYLLKKWASLPKSVQDTISTAETLSDIFLPSSSLLQPEDEMFLKELSSSYSVEKDNDAPLFYREEGNRKFQEKEYTDAAVLYSKGVSHSRPNTEDISLCYANRSAALFHLGQYEACLKDIVEAGMHGYPERLQPKMMVRKTECLVNLGRLQEARQTISDLESSLTAKPTLVLSSYQILQRNVQHLKIKIQEKETLPEPIPAALTNAFEDIALGEENTQISGASLSVSLCTHPLKGRHLVATKDILPGELLVKEDAFVSVLIPGEMPRPHHCLENKWDTRVTSGDLYCHRCLKHTLATVPCGSCSYAKYCSQECMQQAWDLYHSTECSLGGLLLTLGVFCHVALRMTLLARFEDVDRVVRMLCDEVGSTDTCLPESKNLVKAFDYTSQGESEEKSKIGEPPIPGCNVNGKYGSNYNAIFSLLPHTEKHSPEHRFICAISVSALCRQLKADSVQAQTLKSPKLKAVTPGLCADLTVWGAAMLRHMLQLQCNAQAITSICHTGSNESIITNSRQIRLATGIFPVVSLLNHSCRPNTSVSFTGTVATVRAAQRIAKGQEILHCYGPHESRMGVAERQQRLSSQYFFDCRCGACHAETLRAAAAPRWEAFCCKTCRALMQGNDVLSCSNESCTNSVSRDQLVSRLQDLQQQVCMAQKLLRTGKPEQAIQQLLRCREAAESFLSAEHTVLGEIEDGLAQAHATLGNWLKSAAHVQKSLQVVETRHGPSSVEIGHELFKLAQVLFNGLAVPEALSAIWKAERILLVHCGPESEEVRELREMRSCLLDSSFVPVGPLV", "length": 799 }, "evidence": [ { "id": "E1BEP0", "url": "https://omabrowser.org/oma/group/E1BEP0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYR2-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "SMYD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLPVDEWKSYLLQKWASLPTSVQVTISTAETLRDIFLHSSSLLQPEDELFLKRLSKGYLVGKDSDAPLFYREEGNKKFQEKDYTGAAVLYSKGVSHSRPNTEDMSLCHANRSAALFHLGQYETCLKDINRAQTHGYPERLQPKIMLRKAECLVALGRLQEASQTISDLERNFTATPALADVLPQTLQRNLHRLKMKMQEKDSLTESFPAALAKTLEDAALREENEQLSNASSSIGLCVDPLKGRCLVATKDILPGELLVQEDAFVSVLNPGELPPPHHGLDSKWDTRVTNGDLYCHRCLKHTLATVPCDGCSYAKYCSQECLQQAWELYHRTECPLGGLLLTLGVFCHIALRLTLLVGFEDVRKIITKLCDKISNKDICLPESNNQVKTLNYGLGESEKNGNIVETPIPGCDINGKYENNYNAVFNLLPHTENHSPEHKFLCALCVSALCRQLEAASLQAIPTERIVNSSQLKAAVTPELCPDVTIWGVAMLRHMLQLQCNAQAMTTIQHTGPKGSIVTDSRQVRLATGIFPVISLLNHSCSPNTSVSFISTVATIRASQRIRKGQEILHCYGPHKSRMGVAERQQKLRSQYFFDCACPACQTEAHRMAAGPRWEAFCCNSCGAPMQGDDVLRCGSRSCAESAVSRDHLVSRLQDLQQQVRVAQKLLRDGELERAVQRLSGCQRDAESFLWAEHAVVGEIADGLARACAALGDWQKSATHLQRSLYVVEVRHGPSSVEMGHELFKLAQIFFNGFAVPEALSTIQKAEEVLSLHCGPWDDEIQELQKMKSCLLDLPPTPVGPAL", "length": 804 }, "evidence": [ { "id": "E1BEP0", "url": "https://omabrowser.org/oma/group/E1BEP0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BEP0", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BEP0", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BEP0", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "E1BEP0", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "E1BEP0", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "E1BEP0", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "E1BEP0", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "E1BEP0", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "51736", "name": "", "equation": "L-lysyl-[protein] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2YDJ8-1", "Q0P585-1", "P0DPE2-1", "A4FV98-1", "E1BI64-1", "A5PK19-1", "A6QP81-1", "E1B906-1", "G3X834-1", "F1MDT8-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1", "A0ABI0NZS0-1" ], "evidence": [ { "id": "51736", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51736" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MPX3", "gene_name": "PRDM9", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] } ] }, { "uniprot_ac": "A0AAA9SSU7", "gene_name": "", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] } ] }, { "uniprot_ac": "A0ABI0NZS0", "gene_name": "SETD7", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0ABI0NZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0ABI0NZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ] } ] }, { "uniprot_ac": "A4FV98", "gene_name": "EEF1AKMT3", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A4FV98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV98" } ] } ] }, { "uniprot_ac": "A5PK19", "gene_name": "METTL13", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A5PK19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK19" } ] } ] }, { "uniprot_ac": "A6QP81", "gene_name": "METTL21C", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A6QP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QP81" } ] } ] }, { "uniprot_ac": "E1B906", "gene_name": "SETD4", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1B906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1B906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ] } ] }, { "uniprot_ac": "E1BI64", "gene_name": "SETD6", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "E1BI64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI64" } ] } ] }, { "uniprot_ac": "F1MDT8", "gene_name": "SETD2", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "F1MDT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDT8" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "F1MDT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDT8" } ] } ] }, { "uniprot_ac": "G3X834", "gene_name": "", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] } ] }, { "uniprot_ac": "P0DPE2", "gene_name": "EEF1AKMT4-ECE2", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "P0DPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DPE2" } ] }, { "ec_number": "3.4.24.71", "activity": "Hydrolysis of the 21-Trp-|-Val-22 bond in big endothelin to form endothelin 1.", "evidence": [ { "id": "P0DPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DPE2" } ] }, { "ec_number": "3.4.24.71", "activity": "", "evidence": [ { "id": "P0DPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DPE2" } ] } ] }, { "uniprot_ac": "Q0P585", "gene_name": "SMYD2", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q0P585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P585" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "Q0P585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P585" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "Q0P585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P585" } ] } ] }, { "uniprot_ac": "Q2YDJ8", "gene_name": "KMT5A", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q2YDJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDJ8" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "Q2YDJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDJ8" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "Q2YDJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDJ8" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEP0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 802, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEP0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEP0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 335, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BEP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEP0" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 233, "end_pos": 573, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], 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"reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SCML2", "url": "https://www.uniprot.org/uniprotkb/E1BEZ3", "locus": { "chromosome": "X", "start_pos": 125190580, "end_pos": 125069905, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009420", "url": "https://www.ensembl.org/id/ENSBTAG00000009420" } ] } } ], "crossref": [ { "id": "E1BEZ3", "url": "https://alphafold.ebi.ac.uk/entry/E1BEZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009420", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009420", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09578", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09578", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "523477", "url": "https://www.ncbi.nlm.nih.gov/gene/523477", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": 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Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BEZ3", "url": "https://www.orthodb.org/?gene=E1BEZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005228452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228452", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SZW0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZW0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEZ3", "url": "https://www.uniprot.org/uniprotkb/E1BEZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEZ3-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQTVEEDSMGVKKENQERAPQSGTSSVQNDHFQWEKYLEETGSLSAPSEYFRQSKIPPANDFKVGMKLEAHDPRNTTSVCIATVVGVTGARLRLRLDGSDNQNDFWRLVDSPDIQPVGTCEKEGDLLQPPLGYQMNTSSWPMFLLRTLTGSEMAPEAFFKKEPPKPPLNNFKVGMKLEAVDRKNPYLICPATIGNVKGDEVYITFDGWSGAFNYWCKYDCRDIFPVGWCNLTGDILQPLGSNVLITKNTTKTQPPPSKAAQRSMQSPQNSAIILPTHQTKKSGRPKPPGCPSDPKKGSSVKNTTTKKKGPHSGRKGKRIPVICSTSSTSENALAREHGNISYDKDVFPGSSKIVMSTVCVYINKHGNCGPHLDQNKIQQLPDHFGPGPVNVVLRQTVQACVDCAIQSKTVFEFLKPDDRGGEVITAAFDGEIHSIQLPPVNSASFVLRFLENLCHSLQCDNLLSSQPFSSYRGNTHSPEENDQNKPVEEDIMEKKITKRPSEQPLPYVAPLSPKQPKIIVHPSEEEVLPSEEDGMAKKEKLSEESKKSPLSSANSLSPARKNPISTHTPVSMNGSQSMPCTSSLKVVETKSPIKSSQLEVELEVQRESEVEAPSYIAVPDPSVLKQGFSKDPETWSVDEVIQFMKHKDPQKSGPLADLFRQHEIDGKALLLLKSDVIMKYMGLKLGPALKLCYYIEKLKEGKYN", "length": 705, "header": "tr|E1BEZ3-1|E1BEZ3_BOVIN Isoform 1 of Scm polycomb group protein like 2 OS=Bos taurus OX=9913 GN=SCML2 PE=3 SV=5 CANONICAL=E1BEZ3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SZW0-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ3/entry#A0AAA9SZW0-1", "sequence": { 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"MGQTVEEDSMGVKKENQERAPQSGTSSVQNDHFQWEKYLEETGSLSAPSEYFRQSKIPPANDFKVGMKLEAHDPRNTTSVCIATVVGVTGARLRLRLDGSDNQNDFWRLVDSPDIQPVGTCEKEGDLLQPPLGYQMNTSSWPMFLLRTLTGSEMAPEAFFKKEPPKPPLNNFKVGMKLEAVDRKNPYLICPATIGNVKGDEVYITFDGWSGAFNYWCKYDCRDIFPVGWCNLTGDILQPLGSNVLITKNTTKTQPPPSKAAQRSMQSPQNSAIILPTHQTKKSGRPKPPGCPSDPKKGSSVKNTTTKKKGPHSGRKGKRIPVICSTSSTSENALAREHGNISYDKDVFPGSSKIVMSTVCVYINKHGNCGPHLDQNKIQQLPDHFGPGPVNVVLRQTVQACVDCAIQSKTVFEFLKPDDRGGEVITAAFDGEIHSIQLPPVNSASFVLRFLENLCHSLQCDNLLSSQPFSSYRGNTHSPEENDQNKPVEEDIMEKKITKRPSEQPLPYVAPLSPKQPKIIVHPSEEEVLPSEEDGMAKKEKLSEESKKSPLSSANSLSPARKNPISTHTPVSMNGSQSMPCTSSLKVVETKSPIKSSQLEVELEVQRESEVEAPSYIAVPDPSVLKQGFSKDPETWSVDEVIQFMKHKDPQKSGPLADLFRQHEIDGKALLLLKSDVIMKYMGLKLGPALKLCYYIEKLKEGKYN", "length": 705, "header": "tr|E1BEZ3-1|E1BEZ3_BOVIN Isoform 1 of Scm polycomb group protein like 2 OS=Bos taurus OX=9913 GN=SCML2 PE=3 SV=5 CANONICAL=E1BEZ3-1" }, "locus": { "chromosome": "X", "start_pos": 125189576, "end_pos": 125093686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012397.7", "url": "https://www.ensembl.org/id/ENSBTAT00000012397.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012397.7", "url": "https://www.ensembl.org/id/ENSBTAP00000012397.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ3", "url": "https://www.uniprot.org/uniprotkb/E1BEZ3" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ3", "url": "https://www.uniprot.org/uniprotkb/E1BEZ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated 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"name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ3", "url": "https://www.uniprot.org/uniprotkb/E1BEZ3" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ3", "url": "https://www.uniprot.org/uniprotkb/E1BEZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 574, "end_pos": 576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEZ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 705, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEZ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEZ3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ3" }, { "id": "PS51079", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51079" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MBT", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 131, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 574, "end_pos": 576 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEK9-1", "uniprot_ac": "E1BEK9", "uniprot_id": "E1BEK9_BOVIN", "mass": { "chemical_mass": 124286.0, "monoisotopic_mass": 124286.0 }, "refseq": { "ac": "XP_005208537", "name": "regulator of nonsense transcripts 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208537" }, "gene_names": [ { "name": "UPF1", "type": "recommended", "evidence": [ { "id": "E1BEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ] }, { "name": "UPF1", "type": "synonym", "evidence": [ { "id": "XP_005208537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208537" } ] } ], "protein_names": [ { "name": "Regulator of nonsense transcripts 1", "type": "recommended", "evidence": [ { "id": "E1BEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEK9/entry#names_and_taxonomy" } ] }, { "name": "ATP-dependent helicase RENT1", "type": "synonym", "evidence": [ { "id": "E1BEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEK9/entry#names_and_taxonomy" } ] }, { "name": "Nonsense mRNA reducing factor 1", "type": "synonym", "evidence": [ { "id": "E1BEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEK9/entry#names_and_taxonomy" } ] }, { "name": "Up-frameshift suppressor 1 homolog", "type": "synonym", "evidence": [ { "id": "E1BEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEK9/entry#names_and_taxonomy" } ] }, { "name": "regulator of nonsense transcripts 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005208537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208537" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UPF1", "url": "https://www.uniprot.org/uniprotkb/E1BEK9", "locus": { "chromosome": "7", "start_pos": 4337611, "end_pos": 4368677, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020922", "url": "https://www.ensembl.org/id/ENSBTAG00000020922" } ] } } ], "crossref": [ { "id": "E1BEK9", "url": "https://alphafold.ebi.ac.uk/entry/E1BEK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020922", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020922", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18039", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18039", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18808", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18808", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21400", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21400", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532933", "url": "https://www.ncbi.nlm.nih.gov/gene/532933", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "E1BEK9", "url": "https://www.ebi.ac.uk/intact/interactors/id:E1BEK9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR006935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QYMQMNG", "url": "https://omabrowser.org/oma/group/QYMQMNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEK9", "url": "https://www.orthodb.org/?gene=E1BEK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10887", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10887", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10887:SF364", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10887:SF364", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04851", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04851", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005208537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208537", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T089", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T089", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T089-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T089-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEK9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGGGAGAPVGAGPGAAAGQLDAQVGGPEGILQNGAVDDSVAKTSQLLAELNFEEDEEDTYYTKDLPVHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSGNEDLVIIWLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDRSSQGRPSNMYFQTHDQIGMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRGTPKGKTGRGGRQKNRFGLPGPSQTNLPNSQASQDVASQPFSQGALTQGYISMSQPSQMSQPGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY", "length": 1127, "header": "tr|E1BEK9-1|E1BEK9_BOVIN Isoform 1 of Regulator of nonsense transcripts 1 OS=Bos taurus OX=9913 GN=UPF1 PE=3 SV=2 CANONICAL=E1BEK9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T089-1", "url": "https://www.uniprot.org/uniprotkb/E1BEK9/entry#A0AAA9T089-1", "sequence": { "sequence": "MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGGGAGAPVGAGPGAAAGQLDAQGCLPERGTDSEEHLWTSKRTTLLRLQESQPLLLVGGPEGILQNGAVDDSVAKTSQLLAELNFEEDEEDTYYTKDLPVHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDRSSQGRPSNMYFQTHDQIGMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRGTPKGKTGRGGRQKNRFGLPGPSQTNLPNSQASQDVASQPFSQGALTQGYISMSQPSQMSQPGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY", "length": 1149, "header": "tr|A0AAA9T089-1|E1BEK9_BOVIN Computationally mapped isoform of Regulator of nonsense transcripts 1 OS=Bos taurus OX=9913 GN=UPF1 PE=3 SV=1 CANONICAL=E1BEK9-1" }, "locus": { "chromosome": "7", "start_pos": 4368478, "end_pos": 4337617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088279.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088279.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089925.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089925.1" } ] } }, { "isoform_ac": "E1BEK9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEK9/entry#E1BEK9-1", "sequence": { "sequence": "MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGGGAGAPVGAGPGAAAGQLDAQVGGPEGILQNGAVDDSVAKTSQLLAELNFEEDEEDTYYTKDLPVHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSGNEDLVIIWLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDRSSQGRPSNMYFQTHDQIGMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRGTPKGKTGRGGRQKNRFGLPGPSQTNLPNSQASQDVASQPFSQGALTQGYISMSQPSQMSQPGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY", "length": 1127, "header": "tr|E1BEK9-1|E1BEK9_BOVIN Isoform 1 of Regulator of nonsense transcripts 1 OS=Bos taurus OX=9913 GN=UPF1 PE=3 SV=2 CANONICAL=E1BEK9-1" }, "locus": { "chromosome": "7", "start_pos": 4368478, "end_pos": 4337617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027868.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027868.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027868.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027868.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-BTA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0U1RS25-1", "protein_name": "Regulator of nonsense transcripts 1", "gene_name": "Upf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGAGGPGGAGAGGAAGQLDAQVGPEGILQNGAVDDSVAKTSQLLAELNFEEDEEDTYYTKDLPVHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAFFTLPKTDSGNEDLVIIWLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVVIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLSYYKEQKALVEGPLNNLRESLMQFSKPRKLVNTVNPGARFMTTAMYDAREAIIPGSVYDRSSQGRPSNMYFQTHDQISMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRGTPKSKTGRGGRQKNRFGLPGPSQTTLPNSQASQDVASQPFSQGALTQGYVSMSQPSQMSQPGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY", "length": 1124 }, "evidence": [ { "id": "E1BEK9", "url": "https://omabrowser.org/oma/group/E1BEK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1AHU8-1", "protein_name": "ATP-dependent helicase RENT1", "gene_name": "UPF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGPGQAGPGQAQGAPGAGQGPAGPIEAQVNGPDGILQNGAVDDNVAKTSQLLAELNFEEDEEDTYYTKDLPVHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDSSTDYGDEIAIELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDRSSQGRPSNMYFQTHDQIGMISAGPSHVTAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRGAPKGKTGRGGRQKNRFGIPGTSQSNLPNSQASQDVVSQPFSQGPLTQGYISMSQPSQMSQPGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY", "length": 1120 }, "evidence": [ { "id": "E1BEK9", "url": "https://omabrowser.org/oma/group/E1BEK9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RCY6-1", "protein_name": "Regulator of nonsense transcripts 1", "gene_name": "upf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTQGQTQSQLDNQVNGPDGVLPNGEDAVGKTSQLLAELNFEEDEEDTYYTKDLPVHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPTATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSGDMRLMQGDEICLRYKGDMAPLWKGIGHVIKVPDNYGDEIAIELRSSAGAPVEVPHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSSDEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRLKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTRLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMSTAMYDAREAMIPGSVYDRSSTGRPSNMYFQTHDQVGMIGTGPNPMGSLNIPIPFNLVMPPMPPPGYLGQVNGPAAGRGAPKGKTGGRGGRQRNRGTGNHGSGQPNMPNSQASQDLVSQPFSQGPLTQGYITMSQPSQMSQPGLSQPELSQDSYLGDEFKSQMDVALSQDSTYQGERAYQHGGVTGLSQY", "length": 1100 }, "evidence": [ { "id": "E1BEK9", "url": "https://omabrowser.org/oma/group/E1BEK9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P30771-1", "protein_name": "ATP-dependent helicase NAM7", "gene_name": "NAM7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVGSGSHTPYDISNSPSDVNVQPATQLNSTLVEDDDVDNQLFEEAQVTETGFRSPSASDNSCAYCGIDSAKCVIKCNSCKKWFCNTKNGTSSSHIVNHLVLSHHNVVSLHPDSDLGDTVLECYNCGRKNVFLLGFVSAKSEAVVVLLCRIPCAQTKNANWDTDQWQPLIEDRQLLSWVAEQPTEEEKLKARLITPSQISKLEAKWRSNKDATINDIDAPEEQEAIPPLLLRYQDAYEYQRSYGPLIKLEADYDKQLKESQALEHISVSWSLALNNRHLASFTLSTFESNELKVAIGDEMILWYSGMQHPDWEGRGYIVRLPNSFQDTFTLELKPSKTPPPTHLTTGFTAEFIWKGTSYDRMQDALKKFAIDKKSISGYLYYKILGHQVVDISFDVPLPKEFSIPNFAQLNSSQSNAVSHVLQRPLSLIQGPPGTGKTVTSATIVYHLSKIHKDRILVCAPSNVAVDHLAAKLRDLGLKVVRLTAKSREDVESSVSNLALHNLVGRGAKGELKNLLKLKDEVGELSASDTKRFVKLVRKTEAEILNKADVVCCTCVGAGDKRLDTKFRTVLIDESTQASEPECLIPIVKGAKQVILVGDHQQLGPVILERKAADAGLKQSLFERLISLGHVPIRLEVQYRMNPYLSEFPSNMFYEGSLQNGVTIEQRTVPNSKFPWPIRGIPMMFWANYGREEISANGTSFLNRIEAMNCERIITKLFRDGVKPEQIGVITPYEGQRAYILQYMQMNGSLDKDLYIKVEVASVDAFQGREKDYIILSCVRANEQQAIGFLRDPRRLNVGLTRAKYGLVILGNPRSLARNTLWNHLLIHFREKGCLVEGTLDNLQLCTVQLVRPQPRKTERPMNAQFNVESEMGDFPKFQDFDAQSMVSFSGQIGDFGNAFVDNTELSSYINNEYWNFENFKSAFSQKQNRNEIDDRNLYQEEASHLNSNFARELQREEQKHELSKDFSNLGI", "length": 971 }, "evidence": [ { "id": "E1BEK9", "url": "https://omabrowser.org/oma/group/E1BEK9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q92900-1", "protein_name": "Regulator of nonsense transcripts 1", "gene_name": "UPF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGPGGGGAGGPGGAGAGAAAGQLDAQVGPEGILQNGAVDDSVAKTSQLLAELNFEEDEEDTYYTKDLPIHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSGNEDLVIIWLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDRSSQGRPSSMYFQTHDQIGMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRGTPKGKTGRGGRQKNRFGLPGPSQTNLPNSQASQDVASQPFSQGALTQGYISMSQPSQMSQPGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY", "length": 1129 }, "evidence": [ { "id": "E1BEK9", "url": "https://omabrowser.org/oma/group/E1BEK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EPU0-1", "protein_name": "Regulator of nonsense transcripts 1", "gene_name": "Upf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGAGGPGGAGAGGAAGQLDAQVGPEGILQNGAVDDSVAKTSQLLAELNFEEDEEDTYYTKDLPVHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAFFTLPKTDSGNEDLVIIWLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVVIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLSYYKEQKALVEGPLNNLRESLMQFSKPRKLVNTVNPGARFMTTAMYDAREAIIPGSVYDRSSQGRPSNMYFQTHDQISMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRGTPKTKTGRGGRQKNRFGLPGPSQTTLPNSQASQDVASQPFSQGALTQGYVSMSQPSQMSQPGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY", "length": 1124 }, "evidence": [ { "id": "E1BEK9", "url": "https://omabrowser.org/oma/group/E1BEK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FJR0-1", "protein_name": "Regulator of nonsense transcripts 1 homolog", "gene_name": "UPF1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSQQSDLFDTASQPDTVADEYTFLEFNTQGDSEFDYQDFGSPTAWPTPSDSISIADVADRGEGGAAADHHSEASSPSSLSAGAGNGAKVGRGGVGGSGGVSSSSQVDALAAGVGNLNFEETGDDDGFDYGKNDFTEHACKYCGISNPACVVRCNVASCRKWFCNSRGNTSGSHIVNHLVRAKHKEVCLHRDSPLGETILECYNCGCRNVFLLGFISAKTDSVVVLLCRDPCLNVNALKDMNWDLSQWCPLIDDRCFLPWLVKVPSEQEQLRARQISAQQINKIEELWKTNPDATLEDLEKPGVDDEPQPVQPKYEDAYQYQNVFAPLIKLEADYDKMMKESQSKENLTVRWDIGLNKKRVAYFVFPKEENELRLVPGDELRLRYSGDAVHPSWQSVGHVIKLTAQEEVALELRANQGVPIDVNHGFSVDFVWKSTSFDRMQGAMKNFAVDETSVSGYIYHQLLGHEVEAQMVRNTLPRRFGVPGLPELNASQVNAVKSVLQKPISLIQGPPGTGKTVTSAAIVYHMAKQGQGQVLVCAPSNVAVDQLAEKISATGLKVVRLCAKSREAVSSPVEYLTLHYQVRHLDTSEKSELHKLQQLKDEQGELSSSDEKKYKNLKRATEREITQSADVICCTCVGAADLRLSNFRFRQVLIDESTQATEPECLIPLVLGVKQVVLVGDHCQLGPVIMCKKAARAGLAQSLFERLVTLGIKPIRLQVQYRMHPALSEFPSNSFYEGTLQNGVTIIERQTTGIDFPWPVPNRPMFFYVQLGQEEISASGTSYLNRTEAANVEKLVTAFLKSGVVPSQIGVITPYEGQRAYIVNYMARNGSLRQQLYKEIEVASVDSFQGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKVLSKQPLWNGLLTHYKEHECLVEGPLNNLKQSMVQFQKPRKIYNDRRLFYGGGAGMIGNDNFGSGNPNADRRGSRGRAGGSYLPSGPPNGARPGLHPAGYPIPRVPLSPFPGGPPSQPYAIPTRGPVGAVPHAPQPGNHGFGAGRGTSVGGHLPHQQATQHNVGTIGPSLNFPLDSPNSQPSPGGPLSQPGYGSQAFRDGFSMGGISQDFLADDIKSQGSHDPYNMADFATQASPGGFAVDYATQGAHGAFPGNFMNQNSQGGYSRFSGINDFMSQEYMAHGGQGLFTQAGFIDSSQDDGQQNPYGVNNPNLQSQGLPNSLYSQPFAHYNTQPLNLSGPQQSQPNQSSQNPKHPYNG", "length": 1254 }, "evidence": [ { "id": "E1BEK9", "url": "https://omabrowser.org/oma/group/E1BEK9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VYS3-1", "protein_name": "Regulator of nonsense transcripts 1 homolog", "gene_name": "Upf1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSVDTYAPSSALSFLDMDDNELLPGADTQPTQYDYRDFTMPSTSQSQTQNDQLEIAQRCSAGDSHPRLASITNDLADLQFEEEDDEPGSSYVKELPPHACKYCGIHDPATVVMCNNCRKWFCNGRGSTSGSHIINHLVRAKHREVTLHGEGPLGETILECYSCGVRNVFVLGFIPAKADSVVVLLCRQPCAAQNSLKDMNWDQEQWKPLIADRCFLAWLVKQPSEQGQLRARQISAAQINKLEELWKENIEATFQDLEKPGIDSEPAHVLLRYEDGYQYEKTFGPLVRLEAEYDQKLKESATQENIEVRWDVGLNKKTIAYFTLAKTDSDMKLMHGDELRLHYVGELYNPWSEIGHVIKVPDNFGDDVGLELKSSTNAPVKCTSNFTVDFIWKCTSFDRMTRALCKFAIDRNSVSNFIYSRLLGHGRADSNDEVLFRGPQPKLFSAPHLPDLNRSQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQLVKLHGGTVLVCAPSNTAVDQLTEKIHRTNLKVVRVCAKSREAIDSPVSFLALHNQIRNMETNSELKKLQQLKDETGELSSADEKRYRNLKRAAENQLLEAADVICCTCVGAGDGRLSRVKFTSILIDESMQSTEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAARAGLSQSLFERLVVLGIRPFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRLKLDFPWPQPERPMFFLVTQGQEEIAGSGTSFLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRLYQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAKQQLWNHLLNFYKDRKVLVEGSLNNLKESLIHFQKPKKLVNSMNIGAHFMSTIIADAKEVMVPGSIYDRSGGYGQGRQMVGQSMNGGQYGGSGGGPYGNSPLGYGTPSSNSMVGFGLGNGGNGAAGGNNNFGGAGPSWAAAHLHHDSIGYISNEHGAAALGNMPVPVGMFMNMSNIPPRFYNQHQQAIMAVKQNRAIQQQTGNFSPGNSGPGVTGVGVGRSATPGGNKKTNKLGKSRVTGGGTGGAPLTQGSSVCNAAPYSQHPMPLSLQMTQPSGFALSQQPELSQDFGQISQMDGLLSQDVAFNASGERSLNQFSQPY", "length": 1180 }, "evidence": [ { "id": "E1BEK9", "url": "https://omabrowser.org/oma/group/E1BEK9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "telomere maintenance via semi-conservative replication", "id": "GO:0032201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032201", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "regulation of translational termination", "id": "GO:0006449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006449", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "regulation of telomere maintenance", "id": "GO:0032204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032204", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "histone mRNA catabolic process", "id": "GO:0071044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071044", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "cell cycle phase transition", "id": "GO:0044770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044770", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "positive regulation of mRNA metabolic process", "id": "GO:1903313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903313", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 11, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": "https://www.uniprot.org/uniprotkb/E1BEK9" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "E1BEK9", "url": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIS6-1", "uniprot_ac": "E1BIS6", "uniprot_id": "E1BIS6_BOVIN", "mass": { "chemical_mass": 178588.0, "monoisotopic_mass": 178588.0 }, "refseq": {}, "gene_names": [ { "name": "SYNM", "type": "recommended", "evidence": [ { "id": "E1BIS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ] } ], "protein_names": [ { "name": "Synemin", "type": "synonym", "evidence": [ { "id": "E1BIS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SYNM", "url": "https://www.uniprot.org/uniprotkb/E1BIS6", "locus": { "chromosome": "21", "start_pos": 7581549, "end_pos": 7606742, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011752", "url": "https://www.ensembl.org/id/ENSBTAG00000011752" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011752", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011752", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BIS6", "url": "https://www.orthodb.org/?gene=E1BIS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47136", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47136", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47136:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47136:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9T3F4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3F4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIS6-1", "url": "https://www.uniprot.org/uniprotkb/E1BIS6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1624, "header": "tr|E1BIS6-1|E1BIS6_BOVIN Isoform 1 of Synemin OS=Bos taurus OX=9913 GN=SYNM PE=1 SV=3 CANONICAL=E1BIS6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T3F4-1", "url": "https://www.uniprot.org/uniprotkb/E1BIS6/entry#A0AAA9T3F4-1", "sequence": { "sequence": 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"length": 1604, "header": "tr|A0AAA9T3F4-1|E1BIS6_BOVIN Computationally mapped isoform of Synemin OS=Bos taurus OX=9913 GN=SYNM PE=1 SV=1 CANONICAL=E1BIS6-1" }, "locus": { "chromosome": "21", "start_pos": 7606721, "end_pos": 7582039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129550.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129550.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092301.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092301.1" } ] } }, { "isoform_ac": "E1BIS6-1", "url": "https://www.uniprot.org/uniprotkb/E1BIS6/entry#E1BIS6-1", "sequence": { "sequence": "MPPGGAAWPRCPLEPRPDWLEAAPTPARRADQEPRRAGSRPSLRASGAATGPGRRGGGDKTGFGGKQAAGGAPHPSKMLSWRLHTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRSRRGQEGLWAEAEARCTEEARGLRRQLDELSWATALAQGERDALRRELRELQLLGEETRAARGRLDAELDSQRRELQEELAARAALEALLGRLQAERRGLDAARERDVRELRARAAGLTLRYRGRVAGPAAPPLRLRELHEDCALLVTEAWRETVQRYEDEVRELEEALRRGRESRREAEEETRLCAQEAEALRREVLELEQLRALLEEELLRVREASELQAEERQREIAYLEDEKAALTLAMADRLRDYQDLVQVKTGLSLEVATYRALLEGESNPEILIVECIENMPQEFREKSYQYTTSVLQKENERNLFPRQKAPPASFRQSLAPRSQTPVRSDARRDVLGSGYSSFTTAWQENAYQKTASGQTNFRTFSPTPGLLRNTEAQLKTFPERPRTEGTKAPPASSAKESAAAAEPYQERRAEEAAAASEGTWSNERTVIWGKKTEAKATKEQERNRPGTIQTKREEKMFDSKEKASEERNLRWEELTKLDKEARKRESEQMREKAREKESLKEESVKGREIPIRLEASQDSTAKVAPQDLQTPLKEDAGDGTGRGVETREAGFTLGASDTTASLKGGSMTETIAENIVSSILKQFTHSPEAEASAESFPDTKVTYVDRKEVPGDRKAKTEIVVESKLTEEIDISDEAGLDYLLSKDAKEVELKGKSAERLIGDVIRLGLKGKEGRAKVVNVEIIEEPMSYVSSEKEDEFSTPFEVEEIDDVSPSSRGLVEEREEAVYGESDVTCSGDAGQEARRPQESVTHVEEVTEAGDLEGEQSYFVSTPDEHPGAPEREEGSVYGQIHIEEESTIRYSWQDEIVPGSRRRVRRDDVPGEKVVKPVDVPEVPLEGDTASAPWKEQTRSGEFHAKPIVIEKEIKIPHEFHTSIKEGSKEPRHQLVEVIEQLEENLPERMKEELSALTREGQGGPAGVSFDVKKVQSAGSGAVTLVAEVNLSQTVDADQLDLEELSKDEAGEIEKAVESVVRDSLARRRSPGPGSPEAEAGGGFRRWATQELYSSSAGEADAGLASPPGPVSATVEVTSPTGFVHAHVLEDVSQSGGRVQIASPGMWRTEQVSAEGRAAQAVEVSAEGQASWAEGSAGTSRSARLITLGARQSPVSTEVIFPGPDAACPEAGGTEEPGPAELPTEPPRFGRHSPFGSQQFYAQREVIFQAPVSGVGKAGDSSQAEESAGTQTSVKHLQLGTREGLTEQTQLTAPLSGAVELGVREASVLMEAWSGDGTSIRHVTIGPQRHQATEPIVPPPLEFSDSESSTHREGSADETLATSSYTVGRNILVTEKSTFQRAVSESPQEASAEDMSGNEVTSGVSRSFRHIQLGPAEAKTSEHIVFHGPISKTFALAGSVDSPEVSEVADSGRTLRHVALGPKETSFTFQMDVSNVEATSRWTQEARVLFPAGTEAEAPSVSEPGAWRDASSRNDLAAGVSFQGSAGDRHQAPGERGKEQAEFDKTVQLQRMVDQRSVISDEKKVALLYLDSQEEENEGHWF", "length": 1624, "header": "tr|E1BIS6-1|E1BIS6_BOVIN Isoform 1 of Synemin OS=Bos taurus OX=9913 GN=SYNM PE=1 SV=3 CANONICAL=E1BIS6-1" }, "locus": { "chromosome": "21", "start_pos": 7606721, "end_pos": 7582039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015606.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015606.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015606.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015606.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 497, "start_aa": "Thr", "end_pos": 497, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr497", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ], "pmid": "" }, { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ], "pmid": "" }, { "name": "vinculin binding", "id": "GO:0017166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017166", "evidence": [ { "database": "UniProtKB", "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ], "pmid": "" }, { "name": "intermediate filament binding", "id": "GO:0019215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019215", "evidence": [ { "database": "UniProtKB", "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ], "pmid": "" }, { "name": "costamere", "id": "GO:0043034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043034", "evidence": [ { "database": "UniProtKB", "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ], "pmid": "" }, { "name": "neurofilament cytoskeleton", "id": "GO:0060053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060053", "evidence": [ { "database": "UniProtKB", "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intermediate filament cytoskeleton organization", "id": "GO:0045104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045104", "evidence": [ { "database": "UniProtKB", "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ], "pmid": "" }, { "name": "fast-twitch skeletal muscle fiber contraction", "id": "GO:0031443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031443", "evidence": [ { "database": "UniProtKB", "id": "E1BIS6", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1072, "end_pos": 1074, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS6" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 399, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 25, 497 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1072, "end_pos": 1074 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKR8-1", "uniprot_ac": "E1BKR8", "uniprot_id": "E1BKR8_BOVIN", "mass": { "chemical_mass": 119908.0, "monoisotopic_mass": 119908.0 }, "refseq": { "ac": "XP_005218020", "name": "transmembrane protein 132B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218020" }, "gene_names": [ { "name": "TMEM132B", "type": "recommended", "evidence": [ { "id": "E1BKR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKR8" } ] }, { "name": "TMEM132B", "type": "synonym", "evidence": [ { "id": "XP_005218020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218020" } ] } ], "protein_names": [ { "name": "Transmembrane protein 132B", "type": "synonym", "evidence": [ { "id": "E1BKR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKR8/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 132B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005218020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218020" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKR8", "url": "https://www.uniprot.org/uniprotkb/E1BKR8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM132B", "url": "https://www.uniprot.org/uniprotkb/E1BKR8", "locus": { "chromosome": "17", "start_pos": 50308898, "end_pos": 50687308, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006626", "url": "https://www.ensembl.org/id/ENSBTAG00000006626" } ] } } ], "crossref": [ { "id": "E1BKR8", "url": "https://alphafold.ebi.ac.uk/entry/E1BKR8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006626", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006626", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540363", "url": "https://www.ncbi.nlm.nih.gov/gene/540363", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540363", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540363", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VKVSNTC", "url": "https://omabrowser.org/oma/group/VKVSNTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKR8", "url": "https://www.orthodb.org/?gene=E1BKR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13388:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13388:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15706", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15706", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16070", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16070", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23486", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23486", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005218020", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218020", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T3K8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3K8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TI93", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TI93-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRY8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUX6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUX6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKR8", "url": "https://www.uniprot.org/uniprotkb/E1BKR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKR8-1", "url": "https://www.uniprot.org/uniprotkb/E1BKR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPPVRAPPLGLLLALMALRCPVMESRAIVDSLQRFSSLPAYLPTSFHISNAEESFFLKEANQDITRNSSLQTRVESFFIYRARRSPVVNASYGPFSVEKMVPRELMLTSTPFGHVGQFPFNWKVKAHILDSSIYSNRPKVQTLFYITGMGWADDDPAEQLPCVKMFAFPEAREVAASCRLQGTPGLCVAELELLPEWFSSGLDLEPEEEIPALLGGTAMELFFALYPAGPAGQCPLEEDGKWENNIHSGQDSPPPAPPARERIGSVMVYPTQDDLRWSLLNLDENVVLSVPLNLIREGDTATFLVSLTSGSVADHFTLRIKAAAGVKITAVRVSSEDQWAVQEEIDNDSVQTTATLTCVGHHPDTQSRTNGSFYEILQVDFGVDNSSGLAGAQQITWQVEYPVEDAPRELVVSEIFISQTSFVGIVPLAMDSEVLNTAILTGKAVSVPVKVVAVQEDGSVVDVSEAVECRSADEDVIKVSNGCDSVFVNGKEMKSKVDTIVNFTHQHFTSQLEVTVWVPRLPLQVEISDTELSQIKGWRIPVASNRRPTRDSEDEEDEEKKGRGCSLQYQHALVRVLTQFVAESPDSGQLSYMLGPDWQFDITNLVMDFMKVEEPRIAQIQDGRTLVGREPGITTVQVLSPLSDSILAEKTVTVLDDRVTIADLGVQLVAGLSLSLQPHRLDKRAIVSTAAAQDVLQAPQQEAIVSSWILFSDGSVTPLDIYDPKDFSVTVSSLDEMVVSVQASLQSKWPVVVAEGEGQGPLIKLEMMISEPCQKTKRKSILAVGKGNVKVKFEPSIGEHQGGTNDIEGINREYKDHLSNTIDREGNQERAVQEWFQHGASVGHEEHTNKSTTPQSPMEGKDKKMLKSGGPDAFTSFPAQGKSPEPHNPSDLTVTSRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNDVELLENPVDVTLPSEECTTMIDRGLQFEERNFLLNGGSQKTFHSQLLRPSDYVYEKDMKNDPLSSTGPKRKRVKFTSYTTILPEDGGPYTNSILFDSDDSIQWVCPDMGLGESQGFRDYMERLQDQM", "length": 1084, "header": "tr|E1BKR8-1|E1BKR8_BOVIN Isoform 1 of Transmembrane protein 132B OS=Bos taurus OX=9913 GN=TMEM132B PE=3 SV=3 CANONICAL=E1BKR8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T3K8-1", "url": "https://www.uniprot.org/uniprotkb/E1BKR8/entry#A0AAA9T3K8-1", "sequence": { "sequence": "MMESRAIVDSLQRFSSLPAYLPTSFHISNAEESFFLKEANQDITRNSSLQTRVESFFIYRARRSPVVNASYGPFSVEKMVPRELMLTSTPFGHVGQFPFNWKVKAHILDSSIYSNRPKVQTLFYITGMGWADDDPAEQLPCVKMFAFPEAREVAASCRLQGTPGLCVAELELLPEWFSSGLDLEPEEEIPALLGGTAMELFFALYPAGPAGQCPLEEDGKWENNIHSGQDSPPPAPPARERIGSVMVYPTQDDLRWSLLNLDENVVLSVPLNLIREGDTATFLVSLTSGSVADHFTLRIKAAAGVKITAVRVSSEDQWAVQEEIDNDSVQTTATLTCVGHHPDTQSRTNGSFYEILQVDFGVDNSSGLAGAQQITWQVEYPVEDAPRELVVSEIFISQTSFVGIVPLAMDSEVLNTAILTGKAVSVPVKVVAVQEDGSVVDVSEAVECRSADEDVIKVSNGCDSVFVNGKEMKSKVDTIVNFTHQHFTSQLEVTVWVPRLPLQVEISDTELSQIKGWRIPVASNRRPTRDSEDEEDEEKKGRGCSLQYQHALVRVLTQFVAESPDSGQLSYMLGPDWQFDITNLVMDFMKVEEPRIAQIQDGRTLVGREPGITTVQVLSPLSDSILAEKTVTVLDDRVTIADLGVQLVAGLSLSLQPHRLDKRAIVSTAAAQDVLQAPQQEAIVSSWILFSDGSVTPLDIYDPKDFSVTVSSLDEMVVSVQASLQSKWPVVVAEGEGQGPLIKLEMMISEPCQKTKRKSILAVGKGNVKVKFEPSIGEHQGGTNDIEGINREYKDHLSNTIDREGNQERAVQEWFQHGASVGHEEHTNKSTTPQSPMEGKDKKMLKSGGPDAFTSFPAQGKSPEPHNPSDLTVTSRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNDVELLENPVDVTLPSEECTTMIDRGLQFEERNFLLNGGSQKTFHSQLLRPSDYVYEKDMKNDPLSSTGPKRKRVK", "length": 1009, "header": "tr|A0AAA9T3K8-1|E1BKR8_BOVIN Computationally mapped isoform of Transmembrane protein 132B OS=Bos taurus OX=9913 GN=TMEM132B PE=3 SV=1 CANONICAL=E1BKR8-1" }, "locus": { "chromosome": "17", "start_pos": 50535677, "end_pos": 50310061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096059.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096059.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090276.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090276.1" } ] } }, { "isoform_ac": "A0AAA9TI93-1", "url": "https://www.uniprot.org/uniprotkb/E1BKR8/entry#A0AAA9TI93-1", "sequence": { "sequence": "MSSETTRTEVMESRAIVDSLQRFSSLPAYLPTSFHISNAEESFFLKEANQDITRNSSLQTRVESFFIYRARRSPVVNASYGPFSVEKMVPRELMLTSTPFGHVGQFPFNWKVKAHILDSSIYSNRPKVQTLFYITGMGWADDDPAEQLPCVKMFAFPEAREVAASCRLQGTPGLCVAELELLPEWFSSGLDLEPEEEIPALLGGTAMELFFALYPAGPAGQCPLEEDGKWENNIHSGQDSPPPAPPARERIGSVMVYPTQDDLRWSLLNLDENVVLSVPLNLIREGDTATFLVSLTSGSVADHFTLRIKAAAGVKITAVRVSSEDQWAVQEEIDNDSVQTTATLTCVGHHPDTQSRTNGSFYEILQVDFGVDNSSGLAGAQQITWQVEYPVEDAPRELVVSEIFISQTSFVGIVPLAMDSEVLNTAILTGKAVSVPVKVVAVQEDGSVVDVSEAVECRSADEDVIKVSNGCDSVFVNGKEMKSKVDTIVNFTHQHFTSQLEVTVWVPRLPLQVEISDTELSQIKGWRIPVASNRRPTRDSEDEEDEEKKGRGCSLQYQHALVRVLTQFVAESPDSGQLSYMLGPDWQFDITNLVMDFMKVEEPRIAQIQDGRTLVGREPGITTVQVLSPLSDSILAEKTVTVLDDRVTIADLGVQLVAGLSLSLQPHRLDKRAIVSTAAAQDVLQAPQQEAIVSSWILFSDGSVTPLDIYDPKDFSVTVSSLDEMVVSVQASLQSKWPVVVAEGEGQGPLIKLEMMISEPCQKTKRKSILAVGKGNVKVKFEPSIGEHQGGTNDIEGINREYKDHLSNTIDREGNQERAVQEWFQHGASVGHEEHTNKSTTPQSPMEGKDKKMLKSGGPDAFTSFPAQGKSPEPHNPSDLTVTSRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNDVELLENPVDVTLPSEECTTMIDRGLQFEERNFLLNGGSQKTFHSQLLRPSDYVYEKDMKNDPLSSTGPKRKRVKFTSYTTILPEDGGPYTNSILFDSDDSIQWVCPDMGLGESQGFRDYMERLQDQM", "length": 1071, "header": "tr|A0AAA9TI93-1|E1BKR8_BOVIN Computationally mapped isoform of Transmembrane protein 132B OS=Bos taurus OX=9913 GN=TMEM132B PE=3 SV=1 CANONICAL=E1BKR8-1" }, "locus": { "chromosome": "17", "start_pos": 50588136, "end_pos": 50309902, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107256.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107256.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098197.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098197.1" } ] } }, { "isoform_ac": "A0AAA9TIQ4-1", "url": "https://www.uniprot.org/uniprotkb/E1BKR8/entry#A0AAA9TIQ4-1", "sequence": { "sequence": "MMESRAIVDSLQRFSSLPAYLPTSFHISNAEESFFLKEANQDITRNSSLQTRVESFFIYRARRSPVVNASYGPFSVEKMVPRELMLTSTPFGHVGQFPFNWKVKAHILDSSIYSNRPKVQTLFYITGMGWADDDPAEQLPCVKMFAFPEAREVAASCRLQGTPGLCVAELELLPEWFSSGLDLEPEEEIPALLGGTAMELFFALYPAGPAGQCPLEEDGKWENNIHSGQDSPPPAPPARERIGSVMVYPTQDDLRWSLLNLDENVVLSVPLNLIREGDTATFLVSLTSGSVADHFTLRIKAAAGVKITAVRVSSEDQWAVQEEIDNDSVQTTATLTCVGHHPDTQSRTNGSFYEILQVDFGVDNSSGLAGAQQITWQVEYPVEDAPRELVVSEIFISQTSFVGIVPLAMDSEVLNTAILTGKAVSVPVKVVAVQEDGSVVDVSEAVECRSADEDVIKVSNGCDSVFVNGKEMKSKVDTIVNFTHQHFTSQLEVTVWVPRLPLQVEISDTELSQIKGWRIPVASNRRPTRDSEDEEDEEKKGRGCSLQYQHALVRVLTQFVAESPDSGQLSYMLGPDWQFDITNLVMDFMKVEEPRIAQIQDGRTLVGREPGITTVQVLSPLSDSILAEKTVTVLDDRVTIADLGVQLVAGLSLSLQPHRLDKRAIVSTAAAQDVLQAPQQEAIVSSWILFSDGSVTPLDIYDPKDFSVTVSSLDEMVVSVQASLQSKWPVVVAEGEGQGPLIKLEMMISEPCQKTKRKSILAVGKGNVKVKFEPSIGEHQGGTNDIEGINREYKDHLSNTIDREGNQERAVQEWFQHGASVGHEEHTNKSTTPQSPMEGKDKKMLKSGGPDAFTSFPAQGKSPEPHNPSDLTVTSRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNDVELLENPVDVTLPSEECTTMIDRGLQFEERNFLLNGGSQKTFHSQLLRPSDYVYEKDMKNDPLSSTGPKRKRVKFTSYTTILPEDGGPYTNSILFDSDDSIQWVCPDMGLGESQGFRDYMERLQDQM", "length": 1062, "header": "tr|A0AAA9TIQ4-1|E1BKR8_BOVIN Computationally mapped isoform of Transmembrane protein 132B OS=Bos taurus OX=9913 GN=TMEM132B PE=3 SV=1 CANONICAL=E1BKR8-1" }, "locus": { "chromosome": "17", "start_pos": 50535677, "end_pos": 50309902, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129159.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129159.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096786.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096786.1" } ] } }, { "isoform_ac": "A0AAA9TRY8-1", "url": "https://www.uniprot.org/uniprotkb/E1BKR8/entry#A0AAA9TRY8-1", "sequence": { "sequence": "MESRAIVDSLQRFSSLPAYLPTSFHISNAEESFFLKEANQDITRNSSLQTRVESFFIYRARRSPVVNASYGPFSVEKMVPRELMLTSTPFGHVGQFPFNWKVKAHILDSSIYSNRPKVQTLFYITGMGWADDDPAEQLPCVKMFAFPEAREVAASCRLQGTPGLCVAELELLPEWFSSGLDLEPEEEIPALLGGTAMELFFALYPAGPAGQCPLEEDGKWENNIHSGQDSPPPAPPARERIGSVMVYPTQDDLRWSLLNLDENVVLSVPLNLIREGDTATFLVSLTSGSVADHFTLRIKAAAGVKITAVRVSSEDQWAVQEEIDNDSVQTTATLTCVGHHPDTQSRTNGSFYEILQVDFGVDNSSGLAGAQQITWQVEYPVEDAPRELVVSEIFISQTSFVGIVPLAMDSEVLNTAILTGKAVSVPVKVVAVQEDGSVVDVSEAVECRSADEDVIKVSNGCDSVFVNGKEMKSKVDTIVNFTHQHFTSQLEVTVWVPRLPLQVEISDTELSQIKGWRIPVASNRRPTRDSEDEEDEEKKGRGCSLQYQHALVRVLTQFVAESPDSGQLSYMLGPDWQFDITNLVMDFMKVEEPRIAQIQDGRTLVGREPGITTVQVLSPLSDSILAEKTVTVLDDRVTIADLGVQLVAGLSLSLQPHRLDKRAIVSTAAAQDVLQAPQQEAIVSSWILFSDGSVTPLDIYDPKDFSVTVSSLDEMVVSVQASLQSKWPVVVAEGEGQGPLIKLEMMISEPCQKTKRKSILAVGKGNVKVKFEPSIGEHQGGTNDIEGINREYKDHLSNTIDREGNQERAVQEWFQHGASVGHEEHTNKSTTPQSPMEGKDKKMLKSGGPDAFTSFPAQGKSPEPHNPSDLTVTSRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNDVELLENPVDVTLPSEECTTMIDRGLQFEERNFLLNGGSQKTFHSQLLRPSDYVYEKDMKNDPLSSTGPKRKRVKFTSYTTILPEDGGPYTNSILFDSDDSIQWVCPDMGLGESQGFRDYMERLQDQM", "length": 1061, "header": "tr|A0AAA9TRY8-1|E1BKR8_BOVIN Computationally mapped isoform of Transmembrane protein 132B OS=Bos taurus OX=9913 GN=TMEM132B PE=3 SV=1 CANONICAL=E1BKR8-1" }, "locus": { "chromosome": "17", "start_pos": 50530200, "end_pos": 50309902, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110050.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110050.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100087.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100087.1" } ] } }, { "isoform_ac": "A0AAA9TUX6-1", "url": "https://www.uniprot.org/uniprotkb/E1BKR8/entry#A0AAA9TUX6-1", "sequence": { "sequence": "MKSKVDTIVNFTHQHFTSQLEVTVWVPRLPLQVEISDTELSQIKGWRIPVASNRRPTRDSEDEEDEEKKGRGCSLQYQHALVRVLTQFVAESPDSGQLSYMLGPDWQFDITNLVMDFMKVEEPRIAQIQDGRTLVGREPGITTVQVLSPLSDSILAEKTVTVLDDRVTIADLGVQLVAGLSLSLQPHRLDKRAIVSTAAAQDVLQAPQQEAIVSSWILFSDGSVTPLDIYDPKDFSVTVSSLDEMVVSVQASLQSKWPVVVAEGEGQGPLIKLEMMISEPCQKTKRKSILAVGKGNVKVKFEPSIGEHQGGTNDIEGINREYKDHLSNTIDREGNQERAVQEWFQHGASVGHEEHTNKSTTPQSPMEGKDKKMLKSGGPDAFTSFPAQGKSPEPHNPSDLTVTSRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNDVELLENPVDVTLPSEECTTMIDRGLQFEERNFLLNGGSQKTFHSQLLRPSDYVYEKDMKNDPLSSTGPKRKRVKFTSYTTILPEDGGPYTNSILFDSDDSIQWVCPDMGLGESQGFRDYMERLQDQM", "length": 591, "header": "tr|A0AAA9TUX6-1|E1BKR8_BOVIN Computationally mapped isoform of Transmembrane protein 132B OS=Bos taurus OX=9913 GN=TMEM132B PE=3 SV=1 CANONICAL=E1BKR8-1" }, "locus": { "chromosome": "17", "start_pos": 50317913, "end_pos": 50309902, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114222.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114222.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102426.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102426.1" } ] } }, { "isoform_ac": "E1BKR8-1", "url": "https://www.uniprot.org/uniprotkb/E1BKR8/entry#E1BKR8-1", "sequence": { "sequence": "MPPPVRAPPLGLLLALMALRCPVMESRAIVDSLQRFSSLPAYLPTSFHISNAEESFFLKEANQDITRNSSLQTRVESFFIYRARRSPVVNASYGPFSVEKMVPRELMLTSTPFGHVGQFPFNWKVKAHILDSSIYSNRPKVQTLFYITGMGWADDDPAEQLPCVKMFAFPEAREVAASCRLQGTPGLCVAELELLPEWFSSGLDLEPEEEIPALLGGTAMELFFALYPAGPAGQCPLEEDGKWENNIHSGQDSPPPAPPARERIGSVMVYPTQDDLRWSLLNLDENVVLSVPLNLIREGDTATFLVSLTSGSVADHFTLRIKAAAGVKITAVRVSSEDQWAVQEEIDNDSVQTTATLTCVGHHPDTQSRTNGSFYEILQVDFGVDNSSGLAGAQQITWQVEYPVEDAPRELVVSEIFISQTSFVGIVPLAMDSEVLNTAILTGKAVSVPVKVVAVQEDGSVVDVSEAVECRSADEDVIKVSNGCDSVFVNGKEMKSKVDTIVNFTHQHFTSQLEVTVWVPRLPLQVEISDTELSQIKGWRIPVASNRRPTRDSEDEEDEEKKGRGCSLQYQHALVRVLTQFVAESPDSGQLSYMLGPDWQFDITNLVMDFMKVEEPRIAQIQDGRTLVGREPGITTVQVLSPLSDSILAEKTVTVLDDRVTIADLGVQLVAGLSLSLQPHRLDKRAIVSTAAAQDVLQAPQQEAIVSSWILFSDGSVTPLDIYDPKDFSVTVSSLDEMVVSVQASLQSKWPVVVAEGEGQGPLIKLEMMISEPCQKTKRKSILAVGKGNVKVKFEPSIGEHQGGTNDIEGINREYKDHLSNTIDREGNQERAVQEWFQHGASVGHEEHTNKSTTPQSPMEGKDKKMLKSGGPDAFTSFPAQGKSPEPHNPSDLTVTSRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNDVELLENPVDVTLPSEECTTMIDRGLQFEERNFLLNGGSQKTFHSQLLRPSDYVYEKDMKNDPLSSTGPKRKRVKFTSYTTILPEDGGPYTNSILFDSDDSIQWVCPDMGLGESQGFRDYMERLQDQM", "length": 1084, "header": "tr|E1BKR8-1|E1BKR8_BOVIN Isoform 1 of Transmembrane protein 132B OS=Bos taurus OX=9913 GN=TMEM132B PE=3 SV=3 CANONICAL=E1BKR8-1" }, "locus": { "chromosome": "17", "start_pos": 50687200, "end_pos": 50309902, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029679.6", "url": "https://www.ensembl.org/id/ENSBTAT00000029679.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029677.5", "url": "https://www.ensembl.org/id/ENSBTAP00000029677.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540363", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540363", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K3D9-1", "protein_name": "Transmembrane protein 132B", "gene_name": "Tmem132b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAPAASLGLLLALSALRCAESTGRGVADSLQRFASLPAYLPASFHVTDAEEAFFLKEANQDLMRNASLQARSATLFIHRAQSPPAINASYGPFSVEKTVPWDFLLTPTPFGNMERFPFNWRLKSHILDSSIFSNRPKVQTLFYVTGMGWDENDPGDDLPCVKMFAFPEAREVAASCRLQGAPGLCVAQLELLPEWFSSGLDLEPREEIPALLGGTAMELYFALYPANEAGQCPLEEEGKWENNIHSEQEEPQPVLPARERIGSVVVYPTQDDLRWSLVSLDDNVALSIPLNLIREGDTATFLVSLTSGSLAEQFTLRIKAAAGVKITAVRVSHEDQWAVQEEIEQDGTQTTAALSCMGHHPDTQSRANGSFYEILQVDFGVENSSGLAGAQQITWQVEYPVEDSMSELFVSEIFISQTTFVGIVPLTMDTEVLNTAILTGKPVSVPVKVVGVQEDGSVVDVLESVECRSADEDVVKVSNTCDSIFVNGKEMKSKVGTIVNFTHQHFTSQVEITVWVPRLPLQIEISDTELSQIKGWRIPVASNRRPTRESDDEEDEEKKGRGCTLQYQHALVRVLTQFVSESPDLGQLTYMLGPDWQFDITDLVTEFVKVEEPKIAQLQDGRILAGREPGITTVQVLSPLSDSILAEKTVIVLDDRVTITELGVQLVAGLSLSLQPHRADKRAIISTVSAQDVLQAPQQEAIVSSWILFSDGSVTPLDIYEPKDFSVTVSSLDEMVVSIQPNLQTRWPIVVAEGEGQGPLIKLEMSISESCQKNKRKSTLAVGKGNVKVRFEPGTHEQQGGGNDIGGVNREYKGHLSNSIEREGSQERAAQEWFQHGTPVGHKDWTNKSTTPQSPMGGKLLKGGADAFTSFPTQGKLPESNNPGDLTMTSRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNEVELLENPVDITLPSEECTTMIDRGLQFEERNFLLNGSSQKTFHSQLLRPPDYVYEKELKNEPMGSSGPKRKRVKFTSYTTILPEDGGPYTNSILFDSDDSIKWVCQDMGLGDSQDFRDYMERLQDQM", "length": 1078 }, "evidence": [ { "id": "E1BKR8", "url": "https://omabrowser.org/oma/group/E1BKR8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZG85-1", "protein_name": "Transmembrane protein 132B", "gene_name": "TMEM132B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQLMEMRGEGGVRCSWRRWRQSWLLSGLPEASSSCPHSCPPKNQCTLKLISIGSSGSKENEQAHNCPSRMELIEVMCKREIGCVNCKFKNKVVESRGGIMDSVQRFSNLPTYLPATYHICNADVFFFLKETNQDITRNSSLQSRVDSFIIYKSKLPPVLNATYGPFSVEQAVPLDLMLSSASFGFTNEFTFNWKLKSHIIDSSIYSNKPKIQTLFYIAGKDWDDYDPEERLPCVKMFAFLESREVVASCRLTGHLGLCVAELELSPSWFSSPPPLVSEDTAPLEGITVELFYKIYTADGECSPEDEKWENNIHTDQDNEQKALPAMERIGSIVVYPNQDTLKQSSLRLDENVVIRLPLSPVREGDVVTFHVSLADDSLADQFVLRIKTAPGVKILDVRVSDADQWGVQEETDSARTTATITCMHNDPDPESRANITSYEILQMDFEIDNASSLAGAQQITWQVEYPRDDSLSELVVSEIFVSRTMFAGIVPLAMDTEVLNTAILTGKTVSVPVKVVAVQEDGSVVDVSESTECKSADEDVIKVSDRCDSIFVNGKEMKSKVDTIVNFTYEHFTTQLEVTVWVPRLPLQIEISDTELSQIKGWRIPVTSNKRPTRDSEDEEDDEKKGRGCTLQYQHAMVRVLTQFVAESSEFGGYLTYMLGSEWQFDITDLVTDFMKVEDPRIAKLQDGRVLVGREHGITTVQVLSPLSDSILAEKTVVVLDDRVTITDLGVQLVSGLSLSLQISKGNKRAIVSTTSAYDILHTPKQEAIVSAWILFSDGSVTPLDIYDSKDFSITITSLDEMVVSVHQNLQSKWPGVVAEGDGQGPLIKIEMVISEPCQKTKRKSILAVGKGSVKVKFGQKDSDQKESTNDIDDTDKDFKSHASNSIEKTAEQERTAQEWSKNGILSNHEDNANKSTTFVSPIDQESLEDDQLQNNPTAFTGFPAQVEIPGENNPSDLTLTTRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNEVELLENPVDISLPSEECTTMIDRGMQFEESNFLLNGSSQKTLHNHILRSSEYLCEKEVKSEPINPSGPKQKRVKFTSYTTILPEDGGPYTNSILFDSDDNIKWVCQDMNLGDSKELRDYMERLQDNM", "length": 1149 }, "evidence": [ { "id": "E1BKR8", "url": "https://omabrowser.org/oma/group/E1BKR8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F7BAB2-1", "protein_name": "Transmembrane protein 132B", "gene_name": "Tmem132b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAPAASLGLLLALSALRCAESTGRGAADSLQRFSSLPAYLPAGFHVTDAEEAFFLKEANQDLMRNASLQARSATLFIHRAQSPPAINASYGPFSVEKTVPWDFLLMPTPFGNMERFPFNWRLKSHILDSSIFSNRPKVQTLFYVTGMGWDENDPGDDLPCVKMFAFPEAREVAASCRLQGAPGLCVAELELLPEWFSSGLDLEPQEEIPALLGGTAMELYFALYPANEAGQCPLEEEGKWENNIHSEQEEPQPVLPARERIGSVVVYPTQDDLRWSLVTLDDNVALSIPLNLIREGDTATFLVSLTSGSLAEKFTLRIKAAAGVKITAVRVSHEDQWAVQEEIEQDGTQTTAVLSCMGHHPDTQSRANGSFYEILQVDFGVDNSSSLAGAQQITWQVEYPVEDSMSELFVSEIFISQTTFVGIVPLTMDTEILNTAILTGKPVSVPVKVVGVQEDGSVVDVLESVECRSADEDVVKVSNTCDSIFVNGKEMKSKVGTIVNFTHQHFTSQVEITVWVPRLPLQIEISDTELSQIKGWRIPVASNRRPTRESDDEEDEEKKGRGCTLQYQHALVRVLTQFVSESPDLGQLTYMLGPDWQFDITNLVTEFVKVEEPKIAQLQNGRILAGREPGITTVQVLSPLSDSILAEKTVIVLDDRVTITELGVQLVAGLSLSLQPHRADKRAIVSTVAAQDVLQAPQQEAIVSSWILFSDGAVTPLDIYDLKDFSVTVSSLDEMVVSVQPNLQTRWPIVVAEGEGQGPLIKLEMSISESCQKNKRKSTLAVGKGNVKVRFEPGMHEQQGGSNDIGGINREYKGHLSNSIEREGSQERAAQEWFQHGTPVGHEDRTNKSTTPQSPMGGKLLKAGADAFTSFPTQGKLPESSNPGDLTMTSRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNEVELLENPVDITLPSEECTTMIDRGLQFEERNFLLNGSSQKTFHSQLLRPPDYVYEKELKNEPMGSSGPKRKRVKFTSYTTILPEDGGPYTNSILFDSDDSIKWVCQDMGLGDSQDFRDYMERLQDQM", "length": 1078 }, "evidence": [ { "id": "E1BKR8", "url": "https://omabrowser.org/oma/group/E1BKR8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14DG7-1", "protein_name": "Transmembrane protein 132B", "gene_name": "TMEM132B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFGAASRMDTTAVCTGGVTESRGIVDSLQKFSSLPAYLPTNLHISNAEESFFLKEANQDLTRNSSLQARVEPFFIYRARTPPIINASYGPFSVEKIIPQELLLTSTAFGNMDKFPFNWKLKSHILDSSIYSNRPKVQTLFYVTGMGWDDSDLTEDLPCVKMFAFPEAREVAASCRLQGAPGLCVAELELLPEWFSSGLDLEPEEEIPALLGGTTMELFFTLYPADKAGQCPLEEEGKWENNIHSGLESPQQAFPARERIGSVVVYPTQDDLKWSLVSLDENVVISVPLNLVREGDTATFLVSLTSSSVADQFTLRIKAAAGVKITAVRVSSEDQWAVQEEIDNGSTQTSATLTCMGHRPDTQSRVNGSFYEILQVDFGIDNSSDLAGAQQITWQVEYPIEDSMSELVVSEIFVSQTTFVGIVPLAMDTEVLNTAILTGKPVSVPVKVVGVQEDGSVVDVSESVECKSADEDVIKVSNNCDSIFVNGKEMKSKVDTIVNFTHQHFTSQFEVTVWAPRLPLQIEISDTELSQIKGWRIPVAANRRPTRESDDEDDEEKKGRGCSLQYQHATVRVLTQFVAESPDLGQLTYMLGPDWQFDITDLVTEFMKVEEPKIAQLQDGRTLAGREPGITTVQVLSPLSDSILAEKTVIVLDDRVTIAELGVQLVAGMSLSLQPHRADKRAIVSTAAALDVLQSPQQEAIVSSWILFSDGSVTPLDIYDPKDYSVTVSSLDEMVVSVQANLESKWPIVVAEGEGQGPLIKLEMMISEPCQKTKRKSVLAVGKGNVKVKFEPSSDEHQGGSNDIEGINREYKDHLSNSIEREGNQERAVQEWFHRGTPVGQEESTNKSTTPQSPMEGKNKLLKSGGPDAFTSFPTQGKSPDPNNPSDLTVTSRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNEVELLENPVDITLPSEECTTMIDRGLQFEERNFLLNGSSQKTFHSQLLRPSDYVYEKEIKNEPMNSSGPKRKRVKFTSYTTILPEDGGPYTNSILFDSDDNIKWVCQDMGLGDSQDFRDYMESLQDQM", "length": 1078 }, "evidence": [ { "id": "E1BKR8", "url": "https://omabrowser.org/oma/group/E1BKR8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BKR8", "url": "https://www.uniprot.org/uniprotkb/E1BKR8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 850, "end_pos": 852, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKR8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1084, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKR8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKR8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKR8" }, { "id": "PF15706", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15706" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 C-terminal", "eco_id": "ECO_0000259", "start_pos": 878, "end_pos": 958, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKR8" }, { "id": "PF15705", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15705" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 N-terminal", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 107, "start_aa": "Ser", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKR8" }, { "id": "PF23039", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23039" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 cohesin-like", "eco_id": "ECO_0000259", "start_pos": 278, "end_pos": 422, "start_aa": "Trp", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKR8" }, { "id": "PF23486", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23486" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 fifth", "eco_id": "ECO_0000259", "start_pos": 525, "end_pos": 660, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKR8" }, { "id": "PF23481", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23481" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 second Ig-like", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 262, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKR8" }, { "id": "PF23487", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23487" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 sixth", "eco_id": "ECO_0000259", "start_pos": 661, "end_pos": 776, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKR8" }, { "id": "PF16070", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16070" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein family 132 fourth", "eco_id": "ECO_0000259", "start_pos": 425, "end_pos": 522, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 348, "end_pos": 350 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 503, "end_pos": 505 }, { "start_pos": 68, "end_pos": 70 }, { "start_pos": 850, "end_pos": 852 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BH46-1", "uniprot_ac": "E1BH46", "uniprot_id": "E1BH46_BOVIN", "mass": { "chemical_mass": 30168.0, "monoisotopic_mass": 30168.0 }, "refseq": { "ac": "XP_005206951", "name": "electron transfer flavoprotein beta subunit lysine methyltransferase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005206951" }, "gene_names": [ { "name": "ETFBKMT", "type": "recommended", "evidence": [ { "id": "E1BH46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH46" } ] }, { "name": "ETFBKMT", "type": "synonym", "evidence": [ { "id": "XP_005206951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005206951" } ] } ], "protein_names": [ { "name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "type": "recommended", "evidence": [ { "id": "E1BH46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH46/entry#names_and_taxonomy" } ] }, { "name": "ETFB lysine methyltransferase", "type": "synonym", "evidence": [ { "id": "E1BH46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH46/entry#names_and_taxonomy" } ] }, { "name": "Protein N-lysine methyltransferase METTL20", "type": "synonym", "evidence": [ { "id": "E1BH46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH46/entry#names_and_taxonomy" } ] }, { "name": "electron transfer flavoprotein beta subunit lysine methyltransferase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005206951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005206951" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BH46", "url": "https://www.uniprot.org/uniprotkb/E1BH46" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ETFBKMT", "url": "https://www.uniprot.org/uniprotkb/E1BH46", "locus": { "chromosome": "5", "start_pos": 78271230, "end_pos": 78280282, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000877", "url": "https://www.ensembl.org/id/ENSBTAG00000000877" } ] } } ], "crossref": [ { "id": "E1BH46", "url": "https://alphafold.ebi.ac.uk/entry/E1BH46", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000877", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000877", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "530461", "url": "https://www.ncbi.nlm.nih.gov/gene/530461", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:530461", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530461", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RQENYGL", "url": "https://omabrowser.org/oma/group/RQENYGL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BH46", "url": "https://www.orthodb.org/?gene=E1BH46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43648", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43648", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43648:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43648:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06325", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06325", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005206951", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005206951", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "54192", "url": "https://www.rhea-db.org/rhea/54192", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9T5R1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5R1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH46", "url": "https://www.uniprot.org/uniprotkb/E1BH46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH46-1", "url": "https://www.uniprot.org/uniprotkb/E1BH46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALSPGWRVFASFPMNRYVVLWKAVRSSGFPLFPWGHCPWRGTGSLLDPKMKAFLEENTEVTSSGSLTPEIRLRLLTPRCKFWWERADLWPLRDPYWAIYWPGGQALSRYLLDNPDVVRGKSVLDIGSGCGATAIAAKMSGALRILANDIDPIAGMAITLNCELNQLNPFPILIKNILDLEQDKWDIVVLGDMFYDEDLADSLLQWLKNCFETHRTQVLIGDPGRPQFTGHSIQHQLHKVAEYSLPEPTRQDNNGLTISTVWQFQP", "length": 266, "header": "tr|E1BH46-1|E1BH46_BOVIN Isoform 1 of Electron transfer flavoprotein beta subunit lysine methyltransferase OS=Bos taurus OX=9913 GN=ETFBKMT PE=3 SV=1 CANONICAL=E1BH46-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T5R1-1", "url": "https://www.uniprot.org/uniprotkb/E1BH46/entry#A0AAA9T5R1-1", "sequence": { "sequence": "MALSPGWRVFASFPMNRYVVLWKAVRSSGFPLFPWGHCPWRGTGSLLDPKMKAFLEENTEVTSSGSLTPEIRLRLLTPRCKFWWERADLWPLRDPYWAIYWPGGQALSSCRNGYYTKL", "length": 118, "header": "tr|A0AAA9T5R1-1|E1BH46_BOVIN Computationally mapped isoform of Electron transfer flavoprotein beta subunit lysine methyltransferase OS=Bos taurus OX=9913 GN=ETFBKMT PE=3 SV=1 CANONICAL=E1BH46-1" }, "locus": { "chromosome": "5", "start_pos": 78279920, "end_pos": 78272547, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126429.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126429.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093175.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093175.1" } ] } }, { "isoform_ac": "E1BH46-1", "url": "https://www.uniprot.org/uniprotkb/E1BH46/entry#E1BH46-1", "sequence": { "sequence": "MALSPGWRVFASFPMNRYVVLWKAVRSSGFPLFPWGHCPWRGTGSLLDPKMKAFLEENTEVTSSGSLTPEIRLRLLTPRCKFWWERADLWPLRDPYWAIYWPGGQALSRYLLDNPDVVRGKSVLDIGSGCGATAIAAKMSGALRILANDIDPIAGMAITLNCELNQLNPFPILIKNILDLEQDKWDIVVLGDMFYDEDLADSLLQWLKNCFETHRTQVLIGDPGRPQFTGHSIQHQLHKVAEYSLPEPTRQDNNGLTISTVWQFQP", "length": 266, "header": "tr|E1BH46-1|E1BH46_BOVIN Isoform 1 of Electron transfer flavoprotein beta subunit lysine methyltransferase OS=Bos taurus OX=9913 GN=ETFBKMT PE=3 SV=1 CANONICAL=E1BH46-1" }, "locus": { "chromosome": "5", "start_pos": 78279920, "end_pos": 78272234, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001167.3", "url": "https://www.ensembl.org/id/ENSBTAT00000001167.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001167.1", "url": "https://www.ensembl.org/id/ENSBTAP00000001167.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:530461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530461", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480U871-1", "protein_name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "gene_name": "ETFBKMT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALCPGWRAFALFPFNRCGVLGKAVRSTGLPLFPWGHCPWRGTGSFLDPEMKAFLEEHTEVTRSGSLTPEIQLRLLTPRCKFWWERADLWPHSDPYWAIYWPGGQALSRYLLDNPDIVRGRSVLDIGSGCGATAIAAKMSGALRILANDIDPIAGMAITLNCELNRLNPFPVLTKNILDLAQDKWDLVLLGDMFYDEDLADSLHQWLKNCCQAHRTRVLIGDPGRPQFSGHSIQHQLLKVAEYSLPEPTRQENNGLTTSTVWDFQP", "length": 266 }, "evidence": [ { "id": "E1BH46", "url": "https://omabrowser.org/oma/group/E1BH46/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MGD9-1", "protein_name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "gene_name": "Etfbkmt", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAFRLGWKTSRSHWSFLQAVSSGFPLISWRTAGSCLDPEMKAYLEENTEVTSSGSLTPEIQLRLLTPRCKFWWERAELWPYSDPYWAIYWPGGQALSRYLLDNPDVVRGKSVLDLGSGCGATAIAAKMSGASKILANDIDPIAGMAITLNCKLNGLNPFPVLTKNILSTKQGKFDLIVLGDMFYDEDLADSLHLWLENYFWTYRTRVLIGDPGRPQFSGHSIRHQLHKLEEYTLPEPTQQDNSGLTTSAVWDFHP", "length": 255 }, "evidence": [ { "id": "E1BH46", "url": "https://omabrowser.org/oma/group/E1BH46/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0Y1M4-1", "protein_name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "gene_name": "ETFBKMT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAFSSWKRLLLSGRACRRGGPALRWKRCCHWNAGKSLDPEVRAFLEENTEVTSSGHLTPEIRLRLLTPRCRFWREKPDLWPYGDPFWAIYWPGGQALSRYILDNPCVVKGRSVLDLGSGCGATAIAAVMSGASQVLANDIDPIAGTAMILNCELNHVTPFPITIKNIINSEAGNWDLIVLGDMFYDEQLADGLHHWLRKCIRIHQTEVLIGDPGRHQFLSHSIHNQLRKVIEYSLPEYTRQENNGLTSSTVWSYQPSNSLESC", "length": 263 }, "evidence": [ { "id": "E1BH46", "url": "https://omabrowser.org/oma/group/E1BH46/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6P7Q0-1", "protein_name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "gene_name": "Etfbkmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFSLCWKAPRSQWSFLQALNSGFPLFPWRTVGSCLDLKMKAYLEENTEVTSSGSLTPEIQLRLLTPRCKFWWERADLWPYSDPYWAIYWPGGQALSRYLLDNPDVVRGKSVLDLGSGCGATAIAAKMSGASNILANDVDPIAGMAITLNCKLNGLNPFPILTKNILNTRQGKFDLIVLGDMFYDEDLADSLHLWLQNCFWAYGTRVLIGDPGRPQFSGHSIQHQLYQLAEYTLPEPTQQDNNGLTTSAVWDFHP", "length": 255 }, "evidence": [ { "id": "E1BH46", "url": "https://omabrowser.org/oma/group/E1BH46/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80ZM3-1", "protein_name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "gene_name": "Etfbkmt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFSLCWKAPRSPWSFLQAVNNGSPLFLWRTVGSCLDPKMKAYLEENTEVTSSGSLTPEIQLRLLTPRCKFWWERADLWPYSDPYWAIYWPGGQALSRYLLDNPAVVRGKSVLDLGSGCGATAIAAKMSGASKILANDIDPIAGMAITLNCKLNGLNPFPVLTKNILNTQQGKFDLIVLGDMFYDEDLADSLHLWLQNYFWTHGTRVLIGDPGRPQFSGHSIRHQLYQLVEYTLPEPTQQENNGLTTSAVWDFHP", "length": 255 }, "evidence": [ { "id": "E1BH46", "url": "https://omabrowser.org/oma/group/E1BH46/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IXQ9-1", "protein_name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "gene_name": "ETFBKMT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALSLGWKAHRNHCGLLLQALRSSGLLLFPCGQCPWRGAGSFLDPEIKAFLEENTEVTSSGSLTPEIQLRLLTPRCKFWWERADLWPHSDPYWAIYWPGGQALSRYLLDNPDVVRGKSVLDLGSGCGATAIAAKMSGASRILANDIDPIAGMAITLNCELNRLNPFPILIQNILNLEQDKWDLVVLGDMFYDEDLADSLHQWLKKCFWTYRTRVLIGDPGRPQFSGHSIQHHLHKVVEYSLLESTRQENSGLTTSTVWGFQP", "length": 262 }, "evidence": [ { "id": "E1BH46", "url": "https://omabrowser.org/oma/group/E1BH46/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "E1BH46", "url": "https://www.uniprot.org/uniprotkb/E1BH46" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "E1BH46", "url": "https://www.uniprot.org/uniprotkb/E1BH46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "E1BH46", "url": "https://www.uniprot.org/uniprotkb/E1BH46" } ], "pmid": "" }, { "name": "negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase", "id": "GO:1904736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904736", "evidence": [ { "database": "UniProtKB", "id": "E1BH46", "url": "https://www.uniprot.org/uniprotkb/E1BH46" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "E1BH46", "url": "https://www.uniprot.org/uniprotkb/E1BH46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "54192", "name": "", "equation": "L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4FV42-1", "A4FV98-1", "Q17QF2-1", "Q1JPJ9-1", "A0AAA9RVU8-1", "A0A3S5ZPV5-1", "F1MDT8-1", "A0AAA9S7G4-1" ], "evidence": [ { "id": "54192", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54192" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3S5ZPV5", "gene_name": "SMYD5", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3S5ZPV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPV5" } ] }, { "ec_number": "2.1.1.372", "activity": "L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3S5ZPV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPV5" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0A3S5ZPV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPV5" } ] }, { "ec_number": "2.1.1.372", "activity": "", "evidence": [ { "id": "A0A3S5ZPV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPV5" } ] } ] }, { "uniprot_ac": "A0AAA9RVU8", "gene_name": "EEF1AKMT1", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0AAA9RVU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVU8" } ] } ] }, { "uniprot_ac": "A0AAA9S7G4", "gene_name": "EEF1AKMT2", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0AAA9S7G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7G4" } ] } ] }, { "uniprot_ac": "A4FV42", "gene_name": "METTL21A", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A4FV42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV42" } ] } ] }, { 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"Q1JPJ9", "gene_name": "EEF2KMT", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q1JPJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPJ9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BH46-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 266, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BH46-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BH46" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJ67-1", "uniprot_ac": "E1BJ67", "uniprot_id": "E1BJ67_BOVIN", "mass": { "chemical_mass": 59730.0, "monoisotopic_mass": 59730.0 }, "refseq": { "ac": "NP_001193240", "name": "cyclin-L1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193240" }, "gene_names": [ { "name": "CCNL1", "type": "recommended", "evidence": [ { "id": "E1BJ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ67" } ] }, { "name": "CCNL1", "type": "synonym", "evidence": [ { "id": "NP_001193240", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193240" } ] } ], "protein_names": [ { "name": "Cyclin L1", "type": "synonym", "evidence": [ { "id": "E1BJ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ67/entry#names_and_taxonomy" } ] }, { "name": "cyclin-L1", "type": "synonym", "evidence": [ { "id": "NP_001193240", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193240" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJ67", "url": "https://www.uniprot.org/uniprotkb/E1BJ67" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCNL1", "url": "https://www.uniprot.org/uniprotkb/E1BJ67", "locus": { "chromosome": "1", "start_pos": 110461439, "end_pos": 110447554, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003851", "url": "https://www.ensembl.org/id/ENSBTAG00000003851" } ] } } ], "crossref": [ { "id": "E1BJ67", "url": "https://alphafold.ebi.ac.uk/entry/E1BJ67", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003851", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003851", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20592", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20592", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514613", "url": "https://www.ncbi.nlm.nih.gov/gene/514613", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514613", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514613", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHKHRDG", "url": "https://omabrowser.org/oma/group/GHKHRDG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJ67", "url": "https://www.orthodb.org/?gene=E1BJ67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21797", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21797", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193240", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193240", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T658", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T658", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T658-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T658-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ67", "url": "https://www.uniprot.org/uniprotkb/E1BJ67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ67-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGPHPTATAATAVSSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKTEEKSPISVNVKTIKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAVKKHRHERGHHRDRRERSRSFERSHKGKHHGGSRSGHGRHRR", "length": 526, "header": "tr|E1BJ67-1|E1BJ67_BOVIN Isoform 1 of Cyclin L1 OS=Bos taurus OX=9913 GN=CCNL1 PE=3 SV=1 CANONICAL=E1BJ67-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T658-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ67/entry#A0AAA9T658-1", "sequence": { "sequence": "MASGPHPTATAATAVSSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKSDQLHLPKPG", "length": 172, "header": "tr|A0AAA9T658-1|E1BJ67_BOVIN Computationally mapped isoform of Cyclin L1 OS=Bos taurus OX=9913 GN=CCNL1 PE=3 SV=1 CANONICAL=E1BJ67-1" }, "locus": { "chromosome": "1", "start_pos": 110452002, "end_pos": 110448815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109980.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109980.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094242.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094242.1" } ] } }, { "isoform_ac": "E1BJ67-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ67/entry#E1BJ67-1", "sequence": { "sequence": "MASGPHPTATAATAVSSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKTEEKSPISVNVKTIKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAVKKHRHERGHHRDRRERSRSFERSHKGKHHGGSRSGHGRHRR", "length": 526, "header": "tr|E1BJ67-1|E1BJ67_BOVIN Isoform 1 of Cyclin L1 OS=Bos taurus OX=9913 GN=CCNL1 PE=3 SV=1 CANONICAL=E1BJ67-1" }, "locus": { "chromosome": "1", "start_pos": 110460851, "end_pos": 110448815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005025.5", "url": "https://www.ensembl.org/id/ENSBTAT00000005025.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005025.4", "url": "https://www.ensembl.org/id/ENSBTAP00000005025.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 325, "start_aa": "Thr", "end_pos": 325, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr325", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 67, "start_aa": "Thr", "end_pos": 67, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr67", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:514613", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514613", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X2N2-1", "protein_name": "Cyclin L1", "gene_name": "CCNL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASAAAHPAPPPAAVAPAAAVASSAAPPPPPAAPGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLQCETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRAKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICLTTLKLYTRKKPNYELLDKEVEKRKMALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKTEEKSPVPLNTKTIKKEPEERQQASKSPYNGMRKESKRSRSSRSASRSRSRTKSRSRSHTPRRHYNNRRSLSGTYSSRSRSRSRSHSGSPRRHHNHGSPHLKAKHGREELKSANRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKGKHHSSSRSGHSRHRR", "length": 522 }, "evidence": [ { "id": "E1BJ67", "url": "https://omabrowser.org/oma/group/E1BJ67/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LG02-1", "protein_name": "Cyclin L1", "gene_name": "CCNL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASGPHPTATAAAAASSAVPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKTEEKSPISVNVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKGKHHGSSRSGHGRHRR", "length": 526 }, "evidence": [ { "id": "E1BJ67", "url": "https://omabrowser.org/oma/group/E1BJ67/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q52KE7-1", "protein_name": "Cyclin-L1", "gene_name": "Ccnl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGPHPTSTAAAAAAAAASASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNLDGTPALSTLGGFSPASKPSSPREVKAEEKSPVSINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRTSRSASRSRSRTRSRSRSHSPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTREDLKSSNRHGHKRKKSRSRSQSKTRDHSDVTKKHRHERGHHRDRRERSRSFERSHKGKHHGGSRSGHGRHRR", "length": 532 }, "evidence": [ { "id": "E1BJ67", "url": "https://omabrowser.org/oma/group/E1BJ67/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9R1Q2-1", "protein_name": "Cyclin-L1", "gene_name": "Ccnl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGPHPTSTAAAASASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSVIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNLDGTPALSTLGGFSPASKPSSPREVKAEEKSPVSINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTREDLKSSNRHGHKRKKSRSRSQSKTRDHSDVTKKHRHERGHHRDRRERSRSFERSHKGKHHGGSRSGHGRHRR", "length": 527 }, "evidence": [ { "id": "E1BJ67", "url": "https://omabrowser.org/oma/group/E1BJ67/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UK58-1", "protein_name": "Cyclin-L1", "gene_name": "CCNL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASGPHSTATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR", "length": 526 }, "evidence": [ { "id": "E1BJ67", "url": "https://omabrowser.org/oma/group/E1BJ67/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W526-1", "protein_name": "Cyclin-L1", "gene_name": "Dmel\\CG16903", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATRGAGSTVVHTTVTALTVETITNVLTTVTSFHSNSVNISNNNSSSGAAPGADAAGGDAGGVAAAQADANKPIYPRLFNRIVLTLENSLIPEGKIDVTPSSQDGLDHETEKDLRILGCELIQTAGILLRLPQVAMATGQVLFQRFFYSKSFVRHNMETVAMSCVCLASKIEEAPRRIRDVINVFHHIKQVRAQKEISPMVLDPYYTNLKMQVIKAERRVLKELGFCVHVKHPHKLIVMYLQVLQYEKHEKLMQLSWNFMNDSLRTDVFMRYTPEAIACACIYLSARKLNIPLPNSPPWFGIFRVPMADITDICYRVMELYMRSKPVVEKLEAAVDELKKRYIDARNKTKEANTPPAVITVDRNNGSHNAWGGFIQRAIPLPLPSEKSPQKDSRSRSRSRTRTHSRTPRSRSPRSRSPSRERTKKTHRSRSSRSRSRSPPKHKKKSRHYSRSPTRSNSPHSKHRKSKSSRERSEYYSKKDRSGNPGSSNNLGDGDKYRNSVSNSGKHSRYSSSSSRRNSGGGGDGRSGGGGGGGGGGNGNHGSRGGHKHRDGDRSRDRKR", "length": 560 }, "evidence": [ { "id": "E1BJ67", "url": "https://omabrowser.org/oma/group/E1BJ67/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BJ67", "url": "https://www.uniprot.org/uniprotkb/E1BJ67" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BJ67", "url": "https://www.uniprot.org/uniprotkb/E1BJ67" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "E1BJ67", "url": "https://www.uniprot.org/uniprotkb/E1BJ67" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "E1BJ67", "url": "https://www.uniprot.org/uniprotkb/E1BJ67" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BJ67", "url": "https://www.uniprot.org/uniprotkb/E1BJ67" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BJ67", "url": "https://www.uniprot.org/uniprotkb/E1BJ67" } ], "pmid": "" }, { "name": "cyclin L-CDK11 complex", "id": "GO:0180038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180038", "evidence": [ { "database": "UniProtKB", "id": "E1BJ67", "url": "https://www.uniprot.org/uniprotkb/E1BJ67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJ67-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 526, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJ67-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJ67" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ67" }, { "id": "SM01332", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01332" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin C-terminal", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 314, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ67" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 190, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 67, 325 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 }, { "start_pos": 229, "end_pos": 231 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFA9-1", "uniprot_ac": "E1BFA9", "uniprot_id": "E1BFA9_BOVIN", "mass": { "chemical_mass": 49339.0, "monoisotopic_mass": 49339.0 }, "refseq": { "ac": "XP_002696554", "name": "repulsive guidance molecule A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696554" }, "gene_names": [ { "name": "RGMA", "type": "recommended", "evidence": [ { "id": "E1BFA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFA9" } ] }, { "name": "RGMA", "type": "synonym", "evidence": [ { "id": "XP_002696554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696554" } ] } ], "protein_names": [ { "name": "Repulsive guidance molecule BMP co-receptor a", "type": "synonym", "evidence": [ { "id": "E1BFA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFA9/entry#names_and_taxonomy" } ] }, { "name": "repulsive guidance molecule A", "type": "synonym", "evidence": [ { "id": "XP_002696554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696554" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFA9", "url": "https://www.uniprot.org/uniprotkb/E1BFA9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RGMA", "url": "https://www.uniprot.org/uniprotkb/E1BFA9", "locus": { "chromosome": "21", "start_pos": 14030898, "end_pos": 13981505, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018603", "url": "https://www.ensembl.org/id/ENSBTAG00000018603" } ] } } ], "crossref": [ { "id": "E1BFA9", "url": "https://alphafold.ebi.ac.uk/entry/E1BFA9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018603", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018603", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "518756", "url": "https://www.ncbi.nlm.nih.gov/gene/518756", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:518756", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518756", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LCWLCLL", "url": "https://omabrowser.org/oma/group/LCWLCLL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFA9", "url": "https://www.orthodb.org/?gene=E1BFA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31428:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31428:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002696554", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696554", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T688", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T688", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T688-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T688-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFA9", "url": "https://www.uniprot.org/uniprotkb/E1BFA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BFA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPPRERLVVTGRAGWMGMGRGAGRPALGFWPTLAFLLCSFPAASSSCKILKCNSEFWSATAGSHAPAADDAPEFCAALRTYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHSCSKDGPTSQPHLRTLPPPGDSQERSDSPEICHYEKSFHNRAAAPNYRHCGLFGDPHLRTFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFADGSKNGGEKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGCPLNQQIDFQAFRAGAAEGPGAPQPPAASPAPPAPDTFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYARTREPPGRAGAAPGPPPAPWPLLGTLLLLALLPALLGAA", "length": 455, "header": "tr|E1BFA9-1|E1BFA9_BOVIN Isoform 1 of Repulsive guidance molecule BMP co-receptor a OS=Bos taurus OX=9913 GN=RGMA PE=3 SV=3 CANONICAL=E1BFA9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T688-1", "url": "https://www.uniprot.org/uniprotkb/E1BFA9/entry#A0AAA9T688-1", "sequence": { "sequence": "MGMGRGAGRPALGFWPTLAFLLCSFPAAHHHLQELPGVCGPEGVPG", "length": 46, "header": "tr|A0AAA9T688-1|E1BFA9_BOVIN Computationally mapped isoform of Repulsive guidance molecule BMP co-receptor a OS=Bos taurus OX=9913 GN=RGMA PE=3 SV=1 CANONICAL=E1BFA9-1" }, "locus": { "chromosome": "21", "start_pos": 14029230, "end_pos": 14003185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107277.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107277.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093391.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093391.1" } ] } }, { "isoform_ac": "E1BFA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BFA9/entry#E1BFA9-1", "sequence": { "sequence": "MQPPRERLVVTGRAGWMGMGRGAGRPALGFWPTLAFLLCSFPAASSSCKILKCNSEFWSATAGSHAPAADDAPEFCAALRTYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHSCSKDGPTSQPHLRTLPPPGDSQERSDSPEICHYEKSFHNRAAAPNYRHCGLFGDPHLRTFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFADGSKNGGEKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGCPLNQQIDFQAFRAGAAEGPGAPQPPAASPAPPAPDTFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYARTREPPGRAGAAPGPPPAPWPLLGTLLLLALLPALLGAA", "length": 455, "header": "tr|E1BFA9-1|E1BFA9_BOVIN Isoform 1 of Repulsive guidance molecule BMP co-receptor a OS=Bos taurus OX=9913 GN=RGMA PE=3 SV=3 CANONICAL=E1BFA9-1" }, "locus": { "chromosome": "21", "start_pos": 14029894, "end_pos": 13981845, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024758.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024758.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024758.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024758.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:518756", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518756", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A188-1", "protein_name": "Repulsive guidance molecule BMP co-receptor a", "gene_name": "Rgma", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPPRERLVVTGRAGWMGMGRGAGRSALGLWPTLAFLLCSFPAAISPCKILKCNSEFWSATSSGSHAPASDDVPEFCAALRTYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRVRTLPPAGDSQERSDSPEICHYEKSFHKHSAAPNYTHCGLFGDPHLRTFTDHFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPSAFADGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGCPLNQQIDFQAFRANAESPRRPAAASPSPVVPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDGKMLHSNKDKLHLFERTRELPGAVAAAAFPLAPEMLPGTVTLLVLLPLFW", "length": 449 }, "evidence": [ { "id": "E1BFA9", "url": "https://omabrowser.org/oma/group/E1BFA9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SA76-1", "protein_name": "Repulsive guidance molecule BMP co-receptor a", "gene_name": "RGMA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATAGSHAPAPDDTPEFCAALRTYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPHLRTLPPPGDSQERSDSPEICHYEKSFHNRAAAPNYTHCGLFGDPHLRTFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFADGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGCPLNQQIDFQAFRGSAEGPGTRRPAAASPAPSAPDTFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTREPPGRAAAAGLPLAPRPLLGSLLLLPLLLVLLEAA", "length": 453 }, "evidence": [ { "id": "E1BFA9", "url": "https://omabrowser.org/oma/group/E1BFA9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1LVM8-1", "protein_name": "Repulsive guidance molecule A", "gene_name": "rgma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSKRERRGALSRAGWMVMGKGAGPSALQVCQFLALFLSLFPAATLQCKILKCNSEFWASTSSSGPEEEFCTALRAYNSCVRRTARTCRGDLAYHSAQHGIEDLMSQHNCSKEGPTTQPRARTVPPPVLSPPQTDIHIPSDEPEVCHYERSLPHNAAPPNYTHCGFFGDPHLRTFNDDFQTCKVEGAWPLIHNKYLSVQVTNTPVVVGSSATATSKLTIIFNSFQECVDQKTYRAETEDLPAAFIDGSKNGGEGHGANTLRVVEKVPGQHVEIQARYIGTTIVVRKVGHYLTFAVRMPEEVVNSVEDQDNQDLYLCLHGCPANQRIDFRTFKARAAESHGVGRGRPGNPSHGFTYQSAMAKCKERLPVEDLYFQSCVFDLLSSGDINFTLAAYYAFEDVKMLHSNKNKYHLFEKDTIFNSASRKLAFSVLIFISFVIVQLWTDSCFICL", "length": 449 }, "evidence": [ { "id": "E1BFA9", "url": "https://omabrowser.org/oma/group/E1BFA9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6PCX7-1", "protein_name": "Repulsive guidance molecule A", "gene_name": "Rgma", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPPRERLVVTGRAGWMGMGRGAGRSALGLWPTLAFLLCSFPAAISPCKILKCNSEFWSATSSGSHAPASDDVPEFCAALRTYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRVRTLPPAGDSQERSDSPEICHYEKSFHKHSAAPNYTHCGLFGDPHLRTFTDHFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPSAFADGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGCPLNQQIDFQAFRANAESPRRPAAASPSPVVPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDGKMLHSNKDKLHLFERTRELPGAVAAAAAAATTFPLAPQILLGTIPLLVLLPVLW", "length": 454 }, "evidence": [ { "id": "E1BFA9", "url": "https://omabrowser.org/oma/group/E1BFA9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96B86-1", "protein_name": "Repulsive guidance molecule A", "gene_name": "RGMA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC", "length": 450 }, "evidence": [ { "id": "E1BFA9", "url": "https://omabrowser.org/oma/group/E1BFA9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BFA9", "url": "https://www.uniprot.org/uniprotkb/E1BFA9" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "E1BFA9", "url": "https://www.uniprot.org/uniprotkb/E1BFA9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "coreceptor activity", "id": "GO:0015026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026", "evidence": [ { "database": "UniProtKB", "id": "E1BFA9", "url": "https://www.uniprot.org/uniprotkb/E1BFA9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "E1BFA9", "url": "https://www.uniprot.org/uniprotkb/E1BFA9" } ], "pmid": "" }, { "name": "positive regulation of macromolecule metabolic process", "id": "GO:0010604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010604", "evidence": [ { "database": "UniProtKB", "id": "E1BFA9", "url": "https://www.uniprot.org/uniprotkb/E1BFA9" } ], "pmid": "" }, { "name": "regulation of primary metabolic process", "id": "GO:0080090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080090", "evidence": [ { "database": "UniProtKB", "id": "E1BFA9", "url": "https://www.uniprot.org/uniprotkb/E1BFA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFA9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 455, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFA9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFA9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFA9" }, { "id": "PF06534", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06534" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Repulsive guidance molecule C-terminal", "eco_id": "ECO_0000259", "start_pos": 159, "end_pos": 407, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BFA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFA9" }, { "id": "PF06535", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06535" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Repulsive guidance molecule N-terminal", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 117, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 390, "end_pos": 392 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIM1-1", "uniprot_ac": "E1BIM1", "uniprot_id": "E1BIM1_BOVIN", "mass": { "chemical_mass": 15735.0, "monoisotopic_mass": 15735.0 }, "refseq": {}, "gene_names": [ { "name": "GUCA2B", "type": "recommended", "evidence": [ { "id": "E1BIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM1" } ] } ], "protein_names": [ { "name": "Guanylate cyclase activator 2B", "type": "recommended", "evidence": [ { "id": "E1BIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T7A4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7A4#function" }, { "database": "UniProtKB", "id": "ARBA00037765", "url": "https://www.uniprot.org/uniprotkb/ARBA00037765#function" }, { "database": "UniProtKB", "id": "E1BIM1", "url": "https://www.uniprot.org/uniprotkb/E1BIM1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIM1", "url": "https://www.uniprot.org/uniprotkb/E1BIM1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GUCA2B", "url": "https://www.uniprot.org/uniprotkb/E1BIM1", "locus": { "chromosome": "3", "start_pos": 104021061, "end_pos": 104024443, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007194", "url": "https://www.ensembl.org/id/ENSBTAG00000007194" } ] } } ], "crossref": [ { "id": "E1BIM1", "url": "https://alphafold.ebi.ac.uk/entry/E1BIM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007194", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007194", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BIM1", "url": "https://www.orthodb.org/?gene=E1BIM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11318:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11318:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02058", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02058", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8935690", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8935690", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9T7A4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7A4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIM1", "url": "https://www.uniprot.org/uniprotkb/E1BIM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIM1-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDQGAGGQPIKSCQMRKQVGARWTAAGHRESEMASRAVSGYLLCAVALVFLMLLQGTQSVYIQYQGFQVQLESVKQLNDLVGQWVPSPGLQDQSPQPSVCHHPALPLDLRPICASKDVASIFQALRTIANDDCELCVNVACTGCS", "length": 146, "header": "tr|E1BIM1-1|E1BIM1_BOVIN Isoform 1 of Guanylate cyclase activator 2B OS=Bos taurus OX=9913 GN=GUCA2B PE=3 SV=2 CANONICAL=E1BIM1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T7A4-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM1/entry#A0AAA9T7A4-1", "sequence": { "sequence": "GQSRTQGSAQHPITPQGPKEQYQGFQVQLESVKQLNDLVGQWVPSPGLQDQSPQPSVCHHPALPLDLRPICASKDVASIFQALRTIANDDCELCVNVACTGCS", "length": 103, "header": "tr|A0AAA9T7A4-1|E1BIM1_BOVIN Computationally mapped isoform of Guanylate cyclase activator 2B OS=Bos taurus OX=9913 GN=GUCA2B PE=3 SV=1 CANONICAL=E1BIM1-1" }, "locus": { "chromosome": "3", "start_pos": 104024132, "end_pos": 104021118, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130387.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130387.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092625.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092625.1" } ] } }, { "isoform_ac": "E1BIM1-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM1/entry#E1BIM1-1", "sequence": { "sequence": "MSDQGAGGQPIKSCQMRKQVGARWTAAGHRESEMASRAVSGYLLCAVALVFLMLLQGTQSVYIQYQGFQVQLESVKQLNDLVGQWVPSPGLQDQSPQPSVCHHPALPLDLRPICASKDVASIFQALRTIANDDCELCVNVACTGCS", "length": 146, "header": "tr|E1BIM1-1|E1BIM1_BOVIN Isoform 1 of Guanylate cyclase activator 2B OS=Bos taurus OX=9913 GN=GUCA2B PE=3 SV=2 CANONICAL=E1BIM1-1" }, "locus": { "chromosome": "3", "start_pos": 104024389, "end_pos": 104021118, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009465.5", "url": "https://www.ensembl.org/id/ENSBTAT00000009465.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009465.4", "url": "https://www.ensembl.org/id/ENSBTAP00000009465.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8935690", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8935690", "resource": "Reactome", "description": "Digestion" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BIM1", "url": "https://www.uniprot.org/uniprotkb/E1BIM1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanylate cyclase activator activity", "id": "GO:0030250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030250", "evidence": [ { "database": "UniProtKB", "id": "E1BIM1", "url": "https://www.uniprot.org/uniprotkb/E1BIM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIM1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 146, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIM1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIM1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG87-1", "uniprot_ac": "E1BG87", "uniprot_id": "E1BG87_BOVIN", "mass": { "chemical_mass": 108587.0, "monoisotopic_mass": 108587.0 }, "refseq": { "ac": "XP_002689612", "name": "HAUS augmin-like complex subunit 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689612" }, "gene_names": [ { "name": "HAUS6", "type": "recommended", "evidence": [ { "id": "E1BG87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG87" } ] }, { "name": "HAUS6", "type": "synonym", "evidence": [ { "id": "XP_002689612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689612" } ] } ], "protein_names": [ { "name": "HAUS augmin like complex subunit 6", "type": "synonym", "evidence": [ { "id": "E1BG87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG87/entry#names_and_taxonomy" } ] }, { "name": "HAUS augmin-like complex subunit 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002689612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689612" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG87", "url": "https://www.uniprot.org/uniprotkb/E1BG87" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HAUS6", "url": "https://www.uniprot.org/uniprotkb/E1BG87", "locus": { "chromosome": "8", "start_pos": 25180190, "end_pos": 25138098, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019843", "url": "https://www.ensembl.org/id/ENSBTAG00000019843" } ] } } ], "crossref": [ { "id": "E1BG87", "url": "https://alphafold.ebi.ac.uk/entry/E1BG87", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019843", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019843", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538833", "url": "https://www.ncbi.nlm.nih.gov/gene/538833", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538833", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538833", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BG87", "url": "https://www.orthodb.org/?gene=E1BG87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16151:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16151:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002689612", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689612", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T889", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T889", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T889-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T889-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG87", "url": "https://www.uniprot.org/uniprotkb/E1BG87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG87-1", "url": "https://www.uniprot.org/uniprotkb/E1BG87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSAWVTSFEKARLWMYLQALGFEPCLATIACGNTVSHTQFGVNMFDKLNRDAFHIVSYFLFQTLDKSLTKEVFKHCWPPFDQKRDVEFRKLFCEWLKKISAECGSSFPQVVGSLFLFPVGPKFIHIMYHFARFVAVKYIKTHSKNSSIRFTETFNVKPQDLHICLARCLVARNRFLQVLQREDCVTRKYQENAQLSVKQVRNLRSECMGLENQIKKMEPCDDQSNIQEKIQKVRSLWTNVNETLMFLEKEREVVSSVLSLDNNYTLDGTDIAINIPSLLLDKIEKQMCQLHTGNIYEAGKLNILTVFWLLNEVLKVMKCECCQTDQARLTIDLHFLEKETRFQKERLSDLKHMRYKITEALKTIRHSIVEKQEEWHKKWKEFLGLSPFSIIKGSTPAVDLLPPMSPLSFDPASEEAYARSILLQYPASLPVTPKQHIQENNCRRASDTLETKSDPPNSPASFPLQPVPPLGGDIVTLLEKDTKLVTLREKNETVPKKTPEFNVENSSSSNIVKNTDSSACGGSLPAKKSNPFQKEQDHLVEEVARAVLSNSPQLSEEKEVKLEELIDSLISNPFLTRSQIPRTPENLISEIRSSWRKAVDTEDNRSTEPIQVDTERREELPESLPVVHNQKEFSMASFLSAATVSNSSHSHLPEEKVVSDCLECVPQKPVVTTCIGEPTTQNPSDLLNKDIICMQDLDCTTLQNKLLETSQIETFSPAVGNRRNVLGSSEEDNIKISDQSKASYKDFSMYNSMLWNCFQVSSEISSSFKDGDFGILHETLPEVGHISLISPSSTEATFNLEPNSPMHSGIFTEDVVGEKQTTPESDFNLQATCSGYEALKKSPSKQREEIYLSNPEILERHKPELSLTPQKMQTDDMLNFLGIHDLHIDYTKPSSRMSLGERKRSLSPLIKFSPVEQRLKTTIPCSLGELLSNLTEEEILNKSLDAEVSPSDSTR", "length": 956, "header": "tr|E1BG87-1|E1BG87_BOVIN Isoform 1 of HAUS augmin like complex subunit 6 OS=Bos taurus OX=9913 GN=HAUS6 PE=4 SV=5 CANONICAL=E1BG87-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T889-1", "url": "https://www.uniprot.org/uniprotkb/E1BG87/entry#A0AAA9T889-1", "sequence": { "sequence": "MSSAWVTSFEKARLWMYLQALGFEPCLATIACGNTVSHTQFGVNMFDKLNRDAFHIVSYFLFQTLDKSLTKEVFKHCWPPFDQKRDVEFRKLFCEWLKKISAECGSSFPQVVGSLFLFPVGPKFIHIMYHFARFVAVKYIKTHSKNSSIRFTETFNVKPQDLHICLARCLVARNRFLQVLQREDCVTRKYQENAQLSVKQVRNLRSECMGLENQIKKMEPCDDQSNIQEKIQKLHTGNIYEAGKLNILTVFWLLNEVLKVMKCECCQTDQARLTIDLHFLEKETRFQKERLSDLKHMRYKITEALKTIRHSIVEKQEEWHKKWKEFLGLSPFSIIKGSTPAVDLLPPMSPLSFDPASEEAYARSILLQYPASLPVTPKQHIQENNCRRASDTLETKSDPPNSPASFPLQPVPPLGGDIVTLLEKDTKLVTLREKNETVPKKTPEFNVENSSSSNIVKNTDSSACGGSLPAKKSNPFQKEQDHLVEEVARAVLSNSPQLSEEKEVKLEELIDSLISNPFLTRSQIPRTPENLISEIRSSWRKAVDTEDNRSTEPIQVDTERREELPESLPVVHNQKEFSMASFLSAATVSNSSHSHLPEEKVVSDCLECVPQKPVVTTCIGEPTTQNPSDLLNKDIICMQDLDCTTLQNKLLETSQIETFSPAVGNRRNVLGSSEEDNIKISDQSKASYKDFSMYNSMLWNCFQVSSEISSSFKDGDFGILHETLPEVGHISLISPSSTEATFNLEPNSPMHSGIFTEDVVGEKQTTPESDFNLQATCSGYEALKKSPSKQREEIYLSNPEILERHKPELSLTPQKMQTDDMLNFLGIHDLHIDYTKPSSRMSLGERKRSLSPLIKFSPVEQRLKTTIPCSLGELLSNLTEEEILNKSLDAEVSPSDSTR", "length": 899, "header": "tr|A0AAA9T889-1|E1BG87_BOVIN Computationally mapped isoform of HAUS augmin like complex subunit 6 OS=Bos taurus OX=9913 GN=HAUS6 PE=4 SV=1 CANONICAL=E1BG87-1" }, "locus": { "chromosome": "8", "start_pos": 25179186, "end_pos": 25138297, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114956.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114956.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092058.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092058.1" } ] } }, { "isoform_ac": "E1BG87-1", "url": "https://www.uniprot.org/uniprotkb/E1BG87/entry#E1BG87-1", "sequence": { "sequence": "MSSAWVTSFEKARLWMYLQALGFEPCLATIACGNTVSHTQFGVNMFDKLNRDAFHIVSYFLFQTLDKSLTKEVFKHCWPPFDQKRDVEFRKLFCEWLKKISAECGSSFPQVVGSLFLFPVGPKFIHIMYHFARFVAVKYIKTHSKNSSIRFTETFNVKPQDLHICLARCLVARNRFLQVLQREDCVTRKYQENAQLSVKQVRNLRSECMGLENQIKKMEPCDDQSNIQEKIQKVRSLWTNVNETLMFLEKEREVVSSVLSLDNNYTLDGTDIAINIPSLLLDKIEKQMCQLHTGNIYEAGKLNILTVFWLLNEVLKVMKCECCQTDQARLTIDLHFLEKETRFQKERLSDLKHMRYKITEALKTIRHSIVEKQEEWHKKWKEFLGLSPFSIIKGSTPAVDLLPPMSPLSFDPASEEAYARSILLQYPASLPVTPKQHIQENNCRRASDTLETKSDPPNSPASFPLQPVPPLGGDIVTLLEKDTKLVTLREKNETVPKKTPEFNVENSSSSNIVKNTDSSACGGSLPAKKSNPFQKEQDHLVEEVARAVLSNSPQLSEEKEVKLEELIDSLISNPFLTRSQIPRTPENLISEIRSSWRKAVDTEDNRSTEPIQVDTERREELPESLPVVHNQKEFSMASFLSAATVSNSSHSHLPEEKVVSDCLECVPQKPVVTTCIGEPTTQNPSDLLNKDIICMQDLDCTTLQNKLLETSQIETFSPAVGNRRNVLGSSEEDNIKISDQSKASYKDFSMYNSMLWNCFQVSSEISSSFKDGDFGILHETLPEVGHISLISPSSTEATFNLEPNSPMHSGIFTEDVVGEKQTTPESDFNLQATCSGYEALKKSPSKQREEIYLSNPEILERHKPELSLTPQKMQTDDMLNFLGIHDLHIDYTKPSSRMSLGERKRSLSPLIKFSPVEQRLKTTIPCSLGELLSNLTEEEILNKSLDAEVSPSDSTR", "length": 956, "header": "tr|E1BG87-1|E1BG87_BOVIN Isoform 1 of HAUS augmin like complex subunit 6 OS=Bos taurus OX=9913 GN=HAUS6 PE=4 SV=5 CANONICAL=E1BG87-1" }, "locus": { "chromosome": "8", "start_pos": 25179186, "end_pos": 25138297, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031479.7", "url": "https://www.ensembl.org/id/ENSBTAT00000031479.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000031434.7", "url": "https://www.ensembl.org/id/ENSBTAP00000031434.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538833", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538833", "resource": "KEGG Pathway" }, { "id": "R-BTA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-BTA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-BTA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-BTA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-BTA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-BTA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-BTA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "E1BG87", "url": "https://www.uniprot.org/uniprotkb/E1BG87" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "E1BG87", "url": "https://www.uniprot.org/uniprotkb/E1BG87" } ], "pmid": "" }, { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "E1BG87", "url": "https://www.uniprot.org/uniprotkb/E1BG87" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "HAUS complex", "id": "GO:0070652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070652", "evidence": [ { "database": "UniProtKB", "id": "E1BG87", "url": "https://www.uniprot.org/uniprotkb/E1BG87" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BG87", "url": "https://www.uniprot.org/uniprotkb/E1BG87" } ], "pmid": "" }, { "name": "mitotic spindle microtubule", "id": "GO:1990498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990498", "evidence": [ { "database": "UniProtKB", "id": "E1BG87", "url": "https://www.uniprot.org/uniprotkb/E1BG87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BG87", "url": "https://www.uniprot.org/uniprotkb/E1BG87" } ], 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"+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000027722", "url": "https://www.ensembl.org/id/ENSBTAG00000027722" } ] } } ], "crossref": [ { "id": "E1BGE5", "url": "https://alphafold.ebi.ac.uk/entry/E1BGE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000027722", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000027722", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "513707", "url": "https://www.ncbi.nlm.nih.gov/gene/513707", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513707", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513707", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVAKTSW", "url": "https://omabrowser.org/oma/group/WVAKTSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGE5", "url": "https://www.orthodb.org/?gene=E1BGE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997:SF27", 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"https://www.uniprot.org/uniprotkb/E1BGE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGE5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1006, "header": "tr|A0AAA9T9B9-1|E1BGE5_BOVIN Computationally mapped isoform of Importin 7 OS=Bos taurus OX=9913 GN=IPO7 PE=3 SV=1 CANONICAL=E1BGE5-1" }, "locus": { "chromosome": "15", "start_pos": 43234275, "end_pos": 43191366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119610.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119610.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093454.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093454.1" } ] } }, { "isoform_ac": "E1BGE5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGE5/entry#E1BGE5-1", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDEEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038, "header": "tr|E1BGE5-1|E1BGE5_BOVIN Isoform 1 of Importin 7 OS=Bos taurus OX=9913 GN=IPO7 PE=3 SV=1 CANONICAL=E1BGE5-1" }, "locus": { "chromosome": "15", "start_pos": 43234275, "end_pos": 43191366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039955.6", "url": "https://www.ensembl.org/id/ENSBTAT00000039955.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039739.4", "url": "https://www.ensembl.org/id/ENSBTAP00000039739.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:513707", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513707", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZGU8-1", "protein_name": "Importin 7", "gene_name": "IPO7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSVNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGEIPPYSIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAVVEKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLIAAMQHFLPVLKDSFIQLLSDPSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVDRDVPAETLQVDEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHAVTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTSCSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSAQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDLEQIPQVLNQVAGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEEDEETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKTIFQTIQNRNPVWYQTLTQGLNEEQRKQLQDYRKSHLQYKLGGRLNFYTCGGMSICPTSLFSLPYLGVYSFSVNKVIE", "length": 1041 }, "evidence": [ { "id": "E1BGE5", "url": "https://omabrowser.org/oma/group/E1BGE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4AE96-1", "protein_name": "Importin 7", "gene_name": "Ipo7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDDAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "E1BGE5", "url": "https://omabrowser.org/oma/group/E1BGE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4IRR2-1", "protein_name": "Importin beta-like SAD2", "gene_name": "SAD2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLHSLALILRTAALSPIPDERKVSEQQLNQLEHTPQHLVRLLQIAVDGNCDMAVRQIASIQFKNLIAKNWSPEDCGPAVRQQQIFESDKELVRDNILVYVTQVPTLLRSQLGESLKTIIYADYPEQWPRLLDWVKYNLQNQQIYGALFVLRILSRKYEFKSDEERTPVSRIVEETFPQLLTIFNGLIQIPNPSLEIAELMKLICKIFWSSIYLELPRQLFDLNVFNAWMVLFLSVSERPVPVEGQPMDPELRKSWGWWKVKKWTVHILNRLYSRFGDPKLQSPENKPFAQMFQKNYAGRILEGHLNFLNTIRVGGYLPDRVINLLLQYLSNSISKNSMYKLLLPRLDVLLFEIVFPLMCFNDNDQKLWEEDPHEYVRKGYNIIEDLYSPRTASMDFVNELVRKRGKENLPKFVKFVVEIFLSYEKATVEEKPYRQKDGAMLAVGALCDKLKQTDPYKSQLELMLVQHIFPDFNSPVGHLRAKAAWVAGQYAHINFSDQNNFRKALHSVVSGLRDPDLPVRVDSVFALRSFVEACKDLNEIRPILPQLLDEFFKLMNEVENEDLVFTLETIVDKFGEEMAPFAFGLCQNLAAAFWRCLNTSEANDDSDDMGALAAVGCLRAISTILESVSSLPQLFVEIEPTILPIMQKMLTTDGQEVFEEVLEIASYMTFYSPSISLDIWSLWPLMVEALVDWGIDFFPNILVPMDNFISRGTAHFLTCKEPDYQQSLYNVLSTLMTDRNIEDSEIESAPKLIEVVFQNCKGQVDQWVEPYLRLTVDRLQRAETSYVKSLLIQVVANMLYYNPGLTLGVLHNTGLASKVFDLWFQMLQQKRKSGLPANFKREHDKKVCCLGLTSLLALPGGQFPDEALQRVFRATLDLLVAYKNQLAEAAKETEVDYEEEMNGLQSSDDDYDDDGSDGEMDDTEEGDEAQSVKLQKLAAQAKAFHYDDDDDDDSDDDFSDEDEFQSPIDEVDAFVFFVDAIRVMQASDAQRFQNLNQSLDFTYQAIANGIAQHAELRRVEIEKEKQKKLAAASTPVTAL", "length": 1040 }, "evidence": [ { "id": "E1BGE5", "url": "https://omabrowser.org/oma/group/E1BGE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3I7Z8-1", "protein_name": "Importin-7 isoform X1", "gene_name": "Ipo7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "E1BGE5", "url": "https://omabrowser.org/oma/group/E1BGE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95373-1", "protein_name": "Importin-7", "gene_name": "IPO7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "E1BGE5", "url": "https://omabrowser.org/oma/group/E1BGE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P46970-1", "protein_name": "Nonsense-mediated mRNA decay protein 5", "gene_name": "NMD5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDITELLQCFACTLDHNAAVRTNAETHLKNASKVPGFLGACLDIIAADEVPENIKLSASLYFKNKITYGWSAGARQGSNELLDSHVDPDEKPVVKDMLIKTMVSVSKTSPRCIRVLKSALTVIISEDYPSKKWGNLLPNSLELLANEDITVTYVGLLCLAEIFRTYRWKNNDERQDLEELILNYFPALLNYGANVLFQDGKYMNNEQIGELVKLIIKIYKFVSYHDLPFTLQRSESFTPWACFFVSIIQQPLPQEVLAISDIEVRSKNPWVKCKKWALANLYRLFQRYASTSLTRKFQYDEFKQMYCEEFLTQFLQVVFDQIEKWGTGQLWLSDECLYYILNFVEQCVVQKTTWKLVGPHYNVILQHVIFPLLKPTAETLEAFDNDPQEYINRNMDFWDVGYSPDLAALALLTTCVTKRGKTTLQPTLEFMVSTLQSAVGDYNNIMLDNALQIESCLRIFSSIIDRLITKDSPFASEMEKFILTYVLPFFKSQYGFLQSRVCDICSKLGSMDFKDPVITSTIYEGVMNCLNNSSNSLPVELTAALALQTFISDDQFNMKLSEHVVPTMQKLLSLSNDFESDVISGVMQDFVEQFAEQLQPFGVELMNTLVQQFLKLAIDLHETSNLDPDSFTNVDSIPDESDKQMAALGILSTTISILLSFENSPEILKNLEQSFYPAAEFILKNDIEDFYRECCEFVENSTFLLRDITPISWKILELIGECNRKPDSMVSYYLSDFMLALNNILIYGRNELKKNEFYTKIIFEIYQKAVTAEDNSLDDLRVVFDLSQELVLALDDSLPQQYRERLLADVVGSILTQKNELKTNVVFSVTAFNVVISNMITEPLITLQYLKQQGCLEIFFQTWITDYIPNYKRCYDIKLSVLALLKIILKLESNDYSVLNLENLVPQLGSIVTQLASRLPTALRQLANQRKEFSSSGFEEDTKWDENFLDVGDDDENDDEGDLTEKYLELIKNRADSLDFVDGYDAKETFDDLEEDPLTGSILDTVDVYKVFKESIANLQHVDSNRYQGILRHLTPADQELFMGIMNA", "length": 1048 }, "evidence": [ { "id": "E1BGE5", "url": "https://omabrowser.org/oma/group/E1BGE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55CX9-1", "protein_name": "Probable importin-7 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDPIIQTIQLFQHTLHHDANVIKAAEAQLQQIKVTDGYSRILLKILASNEVDISIRQGVSIFLKNMIITKWRGAEDESPITQEDAEFIKENLIDLLVHSHHLVQNQIEAMIEIIANRDFPEKWTSLLPKSIQYINTQDVKLILAGLTSIQLGIKRFRYVTMGDKKKELLYTIVNEIFPLLLQILEFLSQHQTIESALMQKKVIKIFGYAIHFEIPDLLIQPEVFNKWLSQFVRIIQRPITPQENVKHADDCRKNQWWLLKRTTAKLLNLLFRKSATSVRSTDHSSVKALNKLFMPVYSVEVMKVFYEQLSTLEQLYKGVHYERYQQKLIEYFSFAIKYGVTYVAMKPWLSTLIQQVLFPIICFNDRDAELWECDPNEFLRSQFESSMTFATARIEVLNFIIDVVGKRGRANLDMIMGFCIQSLNKYNAATNASEKNPREKDGVLVIISVLSAYLKNISFYKSNLEQMLLLHVFPELSSPHGFLKARACSLFSEFYNIEFTDPVYFSNALKLILGLMSDNDLPVRVKAGTSICNLVRANQGVDELRPILPQLLDKIFSLLSEAESEDLVIAIESIIQRFKHEIAPYAVNLCKNLSEQFLRLLELEESDESGESGFASQECLGVYCTLLRALKDIPDVFNSLEQQIVPILQKLFTSDHMMYLDEALRILTFVTYYPKSISPLVWSLFPQIMNLFDECACDFASSYVNPLDNYISYGTEYFLSNQQYIEMVFNMYKKMVGDINQQPVDAGDCCKIMESLIQRAKGRIDYMIVPVLELACGRLLNTDKNNQKSKEFTVYLLEIIANCIYYNPLISTQYLESKNLVEPIFGLWFNRIKHFQRFYDKKISVLAFSSLLTLNPSPNFVKFGTSLILEKMLQFTKDMLSIEKELDKQEAEREQKIKDGTLKPEEEEFIDENDEEDYFDNHKFEFEFTEIPDNQDCQHDDEGEVFLDDIEKATEYFENGGDLGEDEGDNFDDQNDDDDQDSEEDLFEDEDTPDFETPIDEVDGFEFMINSIQNFFQINPTCIQQISEKQQEKIKKYVASAPARKEKLRLEKEKEEKLKQQQQKK", "length": 1065 }, "evidence": [ { "id": "E1BGE5", "url": "https://omabrowser.org/oma/group/E1BGE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9EPL8-1", "protein_name": "Importin-7", "gene_name": "Ipo7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPGDIAPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDEDAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "E1BGE5", "url": "https://omabrowser.org/oma/group/E1BGE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VSD6-1", "protein_name": "Moleskin", "gene_name": "msk", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEAQKLTELLRATIDPNPEQRKAAEDQLAQIHKIIGFVPTILQIVMQTTVEQPVRQAGAVYLKNLINSSWSDHEAKPGEPIPFSIHEQDRAMIRGAIVDAIVHAPELIRVQLSVCVNHIIKSDFPGRWPQVVDSISIYLQNQDVNGWNGALVTMYQLVKTYEYKRHEERTPLNEAMNLLLPMIYQLMVRLLAEQSEQSVLLQKQILKIYYALTQYTLPLDLITKEIFSQWMEICRQVADRAVPDSSHLDDDERTEFPYWKTKKWALHIMVRMFERYGSPSNVVSEKYQKFAEWYLPTFSQGVLEVLLKILDQYRNRVYVSPRVLTDVLNYLKNAVSHAYTWKLIKPHMVAVIQDVIFPIMSFTDSDQELWESDPYEYIRLKFDIFEDYATPVPAAQSLLHSMCKKRKGILPKAMATIMQIITSPNADNKQKDGALHMIGTLADVLLKKASYRDQVESMLTTYVFPEFQNPAGHMRARACWVLHYFCDVQIKNPQVLAEIMRLTTNALLTDKELPVKVEAAIGLQMFISSQDEAPQYVEAQIKEITKELLTIIRETENEDLTNVMQKIVCTFTEQLLPVATEICQHLATTFSQVLESEEGSDEKAITAMSLLNTIETLLSVMEEHPDVLLNLHPIVINVVGHIFQHNITDFYEETFSLVYDLTAKAISPEMWQMLELIYQVFKKDGIDYFIDIMPALHNYVTVDTPAFLSNPNRLLAILDMCKTMLTSSPGEDPECHAAKLMEVIILQCKGQIDSVIHMFVELALSRLTREVQSSELRTMCLQVVIAALYYNPQLLLSILDKMSQQNNDSISAHFIKQWLHDTDCFLGIHDRKLCVLGLCTLISLGEAKPQVLSEVAGKIVPALILLFDGLKRAYESRAQEEEEDEEEEDGDDCEEALSSDEDDMDEMAPDYLDKLAEFAKTKGNESGFEVKAEIKDDDADSDGDAEESVGDLNETGLESFTTPIDDEENESAIDEYWTFKEVITALSAQDQAWYALLTSNLTPEQAKALQEVVVTADQRKAAKESKLIEKQGGFAFPQTAVPTSFKFGS", "length": 1049 }, "evidence": [ { "id": "E1BGE5", "url": "https://omabrowser.org/oma/group/E1BGE5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BGE5", "url": "https://www.uniprot.org/uniprotkb/E1BGE5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BGE5", "url": "https://www.uniprot.org/uniprotkb/E1BGE5" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "E1BGE5", "url": "https://www.uniprot.org/uniprotkb/E1BGE5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TAB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAB5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVV9", "url": 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"id": "ENSBTAP00000100736.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100736.1" } ] } }, { "isoform_ac": "E1BJ39-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ39/entry#E1BJ39-1", "sequence": { "sequence": "MAENGTLVTEFVLLGFQLSAELQTGLFFVFLLLYLITLGGNLGVTALIQSDPRFQTPMYFFLGHLSFLDICYSSVIVPQLLETLRTGKRTITFERCATQFFFFTLCASAECFLLAVMAYDRCVAVCNALLYASAMTPQTRLGLVAGAYGGAAVNSVVRTGCAFSLSFCKSNHVDFFFCDLPPLLKLACSETRPRERVIYLLAFLVIATSVSVILISYLFIIRAILKIRSAGGKAKTFSTCASHITAVALFFGTLIFIYLKGNMGKSLGEDKIVSVFYTVVIPMLNPLIYSLRNKEVKEALKRALSRMKVSQA", "length": 312, "header": "tr|E1BJ39-1|E1BJ39_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR9I2 PE=3 SV=4 CANONICAL=E1BJ39-1" }, "locus": { "chromosome": "15", "start_pos": 81305095, "end_pos": 81304160, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052988.4", "url": "https://www.ensembl.org/id/ENSBTAT00000052988.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050887.4", "url": 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{ "sequence": "MAPSRLQLGLRAAYSGFSSVAGFSIFFVWTVVYRQPGTAAMGGLAGVLALWVLVTHVMYMQDYWRTWLRGLRGFFFVGALFSAVSVSAFCTFLALAITQHQSLKDPNSYYLSCVWSFISFKWAFLLSLYAHRYRADFADISILSDF", "length": 146 }, "evidence": [ { "id": "E1BKJ0", "url": "https://omabrowser.org/oma/group/E1BKJ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" }, { "name": "phagolysosome membrane", "id": "GO:0061474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061474", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" }, { "name": "endolysosome", "id": "GO:0036019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036019", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" }, { "name": "heme metabolic process", "id": "GO:0042168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042168", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" }, { "name": "heme export", "id": "GO:0097037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097037", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" }, { "name": "heme export from vacuole to cytoplasm", "id": "GO:0140357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140357", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" }, { "name": "heme transport", "id": "GO:0015886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015886", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "heme transmembrane transporter activity", "id": "GO:0015232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015232", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "E1BKJ0", "url": "https://www.uniprot.org/uniprotkb/E1BKJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "75443", "name": "", "equation": "heme b(in) = heme b(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "75443", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/75443" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKJ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 146, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKJ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKJ0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEC6-1", "uniprot_ac": "E1BEC6", "uniprot_id": "E1BEC6_BOVIN", "mass": { "chemical_mass": 105138.0, "monoisotopic_mass": 105138.0 }, "refseq": { "ac": "NP_001179256", "name": "adhesion G-protein coupled receptor F1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179256" }, "gene_names": [ { "name": "ADGRF1", "type": "recommended", "evidence": [ { "id": "E1BEC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEC6" } ] }, { "name": "ADGRF1", "type": "synonym", "evidence": [ { "id": "NP_001179256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179256" } ] }, { "name": "GPR110", "type": "synonym", "evidence": [ { "id": "NP_001179256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179256" } ] } ], "protein_names": [ { "name": "Adhesion G protein-coupled receptor F1", "type": "synonym", "evidence": [ { "id": "E1BEC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEC6/entry#names_and_taxonomy" } ] }, { "name": "G protein-coupled receptor 110", "type": "synonym", "evidence": [ { "id": "NP_001179256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179256" } ] }, { "name": "adhesion G-protein coupled receptor F1", "type": "synonym", "evidence": [ { "id": "NP_001179256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179256" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEC6", "url": "https://www.uniprot.org/uniprotkb/E1BEC6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADGRF1", "url": "https://www.uniprot.org/uniprotkb/E1BEC6", "locus": { "chromosome": "23", "start_pos": 20213896, "end_pos": 20258717, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021609", "url": "https://www.ensembl.org/id/ENSBTAG00000021609" } ] } } ], "crossref": [ { "id": "E1BEC6", "url": "https://alphafold.ebi.ac.uk/entry/E1BEC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021609", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021609", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "512637", "url": "https://www.ncbi.nlm.nih.gov/gene/512637", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512637", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512637", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BEC6", "url": "https://www.orthodb.org/?gene=E1BEC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45813", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45813", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45813:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45813:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179256", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179256", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TC25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TC25-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEC6", "url": "https://www.uniprot.org/uniprotkb/E1BEC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEC6-1", "url": "https://www.uniprot.org/uniprotkb/E1BEC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFKGHPERKSQTVTPAVCVLSRTRRDQQKMRFLPLWLFSFLTITEGRDGFLERDEGIKTKQELIVNKEKPLGSIQEYELLLQVHYRNSKEKRELKEFLKFCALSSFFLPEPVKIIRAKATTYCGYQNRALRCACEDSYSWFPPQCLDPQNCSLLKAGSPQTCDCHSSNLTQSVYFCERTKVWGTFKINKKFTEDLLDSSSAKYAKYTTGIEMQLKEAYKGIQGFESVRVIQFRDGSIVVGYEVVGSSGTSELLSGIEQMVEKAKTYLRQLYTLEENSFRVFGEAQCNSIAFGFGSENDEYTLPCSLGYIGNITVRCQPSGWHILEEMCVLSELEELKKNSRELARNSTDAEAAVSSLVQKLSMVIQQSPSTTAGNLASVVSILGNISSLRKSFTVSNSTMENVINIADHILNSASLTNWTVLLKKEKNASSQLLESLENISTLVPSTALPLHFSRDFINWKGIPVSANLSNQGYNYETEFPPQNTPSPITGHVSIGPGQFKKHLPHTIISMTSLTLGNILPIAENKNAQVNGPLISIIIPNSSIHEISLTFSKMKLNLSQPQCVFWDFSHLQWTDTGCHLENETANLVTCLCTHLTSYSVLMSSIVPPAIVPIVKWITFVGLGVSIGSLILCLTIQGLFWKQVNKNQTSHSRHICIVNIALCLLIADVWFIVAATVDTNSGVCTAAVFFAHLFYLSLFFWMLLLGFLLAYRVIFVFHHMATPLMVAVGFCLGYGCPLIISIVTFLVTQPSDGYKRKDACWLNWSDGSKPLLAFAVPALTIVAVNLVVVLLVLTKLWRPAVGERLAQDNKATVKRIGRSLLVLTPLLGLTWGFGIVTMADGQNLSWHVIFAFLNAFQGLFILCFGILLDSKLRQLLLNKLSPLSCWDQTSKQKLSDSSVTLRFEKPFNPFQQKGCYVFSYTSESSHDIMLTQFSSAEQSGES", "length": 942, "header": "tr|E1BEC6-1|E1BEC6_BOVIN Isoform 1 of Adhesion G protein-coupled receptor F1 OS=Bos taurus OX=9913 GN=ADGRF1 PE=3 SV=4 CANONICAL=E1BEC6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TC25-1", "url": "https://www.uniprot.org/uniprotkb/E1BEC6/entry#A0AAA9TC25-1", "sequence": { "sequence": "MKFKGHPERKRDEGIKTKQELIVNKEKPLGSIQEYELLLQVHYRNSKEKRELKEFLKFCALSSFFLPEPVKIIRAKATTYCGYQNRALRCACEDSYSWFPPQCLDPQNCSLLKAGSPQTCDCHSSNLTQSVYFCERTKVWGTFKINKKFTEDLLDSSSAKYAKYTTGIEMQLKEAYKGIQGFESVRVIQFRDGSIVVGYEVVGSSGTSELLSGIEQMVEKAKTYLRQLYTLEENSFRVFGEAQCNSIAFGFGSENDEYTLPCSLGYIGNITVRCQPSGWHILEEMCVLSELEELKKNSRELARNSTDAEAAVSSLVQKLSMVIQQSPSTTAGNLASVVSILGNISSLRKSFTVSNSTMENVINIADHILNSASLTNWTVLLKKEKNASSQLLESLENISTLVPSTALPLHFSRDFINWKGIPVSANLSNQGYNYETEFPPQNTPSPITGHVSIGPGQFKKHLPHTIISMTSLTLGNILPIAENKNAQVNGPLISIIIPNSSIHEISLTFSKMKLNLSQPQCVFWDFSHLQWTDTGCHLENETANLVTCLCTHLTSYSVLMSSIVPPAIVPIVKWITFVGLGVSIGSLILCLTIQGLFWKQVNKNQTSHSRHICIVNIALCLLIADVWFIVAATVDTNSGVCTAAVFFAHLFYLSLFFWMLLLGFLLAYRVIFVFHHMATPLMVAVGFCLGYGCPLIISIVTFLVTQPSDGYKRKDACWLNWSDGSKPLLAFAVPALTIVAVNLVVVLLVLTKLWRPAVGERLAQDNKATVKRIGRSLLVLTPLLGLTWGFGIVTMADGQNLSWHVIFAFLNAFQGLFILCFGILLDSKLRQLLLNKLSPLSCWDQTSKQKLSDSSVTLRFEKPFNPFQQKGCYVFSYTSESSHDIMLTQFSSAEQSGES", "length": 899, "header": "tr|A0AAA9TC25-1|E1BEC6_BOVIN Computationally mapped isoform of Adhesion G protein-coupled receptor F1 OS=Bos taurus OX=9913 GN=ADGRF1 PE=3 SV=1 CANONICAL=E1BEC6-1" }, "locus": { "chromosome": "23", "start_pos": 20244033, "end_pos": 20214126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091493.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091493.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094260.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094260.1" } ] } }, { "isoform_ac": "E1BEC6-1", "url": "https://www.uniprot.org/uniprotkb/E1BEC6/entry#E1BEC6-1", "sequence": { "sequence": "MKFKGHPERKSQTVTPAVCVLSRTRRDQQKMRFLPLWLFSFLTITEGRDGFLERDEGIKTKQELIVNKEKPLGSIQEYELLLQVHYRNSKEKRELKEFLKFCALSSFFLPEPVKIIRAKATTYCGYQNRALRCACEDSYSWFPPQCLDPQNCSLLKAGSPQTCDCHSSNLTQSVYFCERTKVWGTFKINKKFTEDLLDSSSAKYAKYTTGIEMQLKEAYKGIQGFESVRVIQFRDGSIVVGYEVVGSSGTSELLSGIEQMVEKAKTYLRQLYTLEENSFRVFGEAQCNSIAFGFGSENDEYTLPCSLGYIGNITVRCQPSGWHILEEMCVLSELEELKKNSRELARNSTDAEAAVSSLVQKLSMVIQQSPSTTAGNLASVVSILGNISSLRKSFTVSNSTMENVINIADHILNSASLTNWTVLLKKEKNASSQLLESLENISTLVPSTALPLHFSRDFINWKGIPVSANLSNQGYNYETEFPPQNTPSPITGHVSIGPGQFKKHLPHTIISMTSLTLGNILPIAENKNAQVNGPLISIIIPNSSIHEISLTFSKMKLNLSQPQCVFWDFSHLQWTDTGCHLENETANLVTCLCTHLTSYSVLMSSIVPPAIVPIVKWITFVGLGVSIGSLILCLTIQGLFWKQVNKNQTSHSRHICIVNIALCLLIADVWFIVAATVDTNSGVCTAAVFFAHLFYLSLFFWMLLLGFLLAYRVIFVFHHMATPLMVAVGFCLGYGCPLIISIVTFLVTQPSDGYKRKDACWLNWSDGSKPLLAFAVPALTIVAVNLVVVLLVLTKLWRPAVGERLAQDNKATVKRIGRSLLVLTPLLGLTWGFGIVTMADGQNLSWHVIFAFLNAFQGLFILCFGILLDSKLRQLLLNKLSPLSCWDQTSKQKLSDSSVTLRFEKPFNPFQQKGCYVFSYTSESSHDIMLTQFSSAEQSGES", "length": 942, "header": "tr|E1BEC6-1|E1BEC6_BOVIN Isoform 1 of Adhesion G protein-coupled receptor F1 OS=Bos taurus OX=9913 GN=ADGRF1 PE=3 SV=4 CANONICAL=E1BEC6-1" }, "locus": { "chromosome": "23", "start_pos": 20244033, "end_pos": 20214126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028795.8", "url": "https://www.ensembl.org/id/ENSBTAT00000028795.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028795.7", "url": "https://www.ensembl.org/id/ENSBTAP00000028795.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 15, "start_aa": "Thr", "end_pos": 15, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr15", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:512637", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512637", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BEC6", "url": "https://www.uniprot.org/uniprotkb/E1BEC6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BEC6", "url": "https://www.uniprot.org/uniprotkb/E1BEC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "E1BEC6", "url": "https://www.uniprot.org/uniprotkb/E1BEC6" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "E1BEC6", "url": "https://www.uniprot.org/uniprotkb/E1BEC6" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "E1BEC6", "url": "https://www.uniprot.org/uniprotkb/E1BEC6" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "E1BEC6", "url": "https://www.uniprot.org/uniprotkb/E1BEC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 15 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 440, "end_pos": 442 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 542, "end_pos": 544 }, { "start_pos": 558, "end_pos": 560 }, { "start_pos": 583, "end_pos": 585 }, { "start_pos": 647, "end_pos": 649 }, { "start_pos": 763, "end_pos": 765 }, { "start_pos": 843, "end_pos": 845 } ] }, "class_list": [], "section_stats": [ { 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKS3-1", "uniprot_ac": "E1BKS3", "uniprot_id": "E1BKS3_BOVIN", "mass": { "chemical_mass": 47969.0, "monoisotopic_mass": 47969.0 }, "refseq": { "ac": "XP_005208282", "name": "TNFAIP3-interacting protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208282" }, "gene_names": [ { "name": "TNIP2", "type": "recommended", "evidence": [ { "id": "E1BKS3", "database": "UniProtKB", "url": 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Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. 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"database": "Ensembl Gene", "id": "ENSBTAG00000015126", "url": "https://www.ensembl.org/id/ENSBTAG00000015126" } ] } } ], "crossref": [ { "id": "E1BKS3", "url": "https://alphafold.ebi.ac.uk/entry/E1BKS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015126", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015126", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100336382", "url": "https://www.ncbi.nlm.nih.gov/gene/100336382", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31882", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31882", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31882:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31882:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12180", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12180", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5684264", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5684264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5689896", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689896", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005208282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208282", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TCM0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCM0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TF19", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TF19-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKS3", "url": "https://www.uniprot.org/uniprotkb/E1BKS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKS3-1", "url": "https://www.uniprot.org/uniprotkb/E1BKS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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}, { "id": "PTHR11318:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11318:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02058", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02058", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8935690", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8935690", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TH77", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TH77-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIM0", "url": "https://www.uniprot.org/uniprotkb/E1BIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIM0-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MITQRSELCAFCVPGIESQCFPLASRTSHSSLLGAATMNTFLLSALCLLGAWATLTGGVIVKDGDFSFSLESVKKLKDLQELQELQEPRIPRNPGGHIASNLCSLPTFPEELKPLCKESNAQEILDRLGAIAADPSTCEICAYAACAGC", "length": 149, "header": "tr|E1BIM0-1|E1BIM0_BOVIN Isoform 1 of Guanylin OS=Bos taurus OX=9913 GN=GUCA2A PE=3 SV=2 CANONICAL=E1BIM0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TH77-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM0/entry#A0AAA9TH77-1", "sequence": { "sequence": "MSKAWLCPTDLLLSPASHTFRFQTQKDQEERRETVRETQDGDFSFSLESVKKLKDLQELQELQEPRIPRNPGGHIASNLCSLPTFPEELKPLCKESNAQEILDRLGAIAADPSTCEICAYAACAGC", "length": 126, "header": "tr|A0AAA9TH77-1|E1BIM0_BOVIN Computationally mapped isoform of Guanylin OS=Bos taurus OX=9913 GN=GUCA2A PE=3 SV=1 CANONICAL=E1BIM0-1" }, "locus": { "chromosome": "3", "start_pos": 104017320, "end_pos": 104015738, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135657.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135657.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096415.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096415.1" } ] } }, { "isoform_ac": "E1BIM0-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM0/entry#E1BIM0-1", "sequence": { "sequence": "MITQRSELCAFCVPGIESQCFPLASRTSHSSLLGAATMNTFLLSALCLLGAWATLTGGVIVKDGDFSFSLESVKKLKDLQELQELQEPRIPRNPGGHIASNLCSLPTFPEELKPLCKESNAQEILDRLGAIAADPSTCEICAYAACAGC", "length": 149, "header": "tr|E1BIM0-1|E1BIM0_BOVIN Isoform 1 of Guanylin OS=Bos taurus OX=9913 GN=GUCA2A PE=3 SV=2 CANONICAL=E1BIM0-1" }, "locus": { "chromosome": "3", "start_pos": 104017320, "end_pos": 104014650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009466.5", "url": "https://www.ensembl.org/id/ENSBTAT00000009466.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009466.4", "url": "https://www.ensembl.org/id/ENSBTAP00000009466.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8935690", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8935690", "resource": "Reactome", "description": "Digestion" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BIM0", "url": "https://www.uniprot.org/uniprotkb/E1BIM0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanylate cyclase activator activity", "id": "GO:0030250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030250", "evidence": [ { "database": "UniProtKB", "id": "E1BIM0", "url": "https://www.uniprot.org/uniprotkb/E1BIM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIM0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 149, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIM0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIM0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BF42-1", "uniprot_ac": "E1BF42", "uniprot_id": "E1BF42_BOVIN", "mass": { "chemical_mass": 60497.0, "monoisotopic_mass": 60497.0 }, "refseq": {}, "gene_names": [ { "name": "M1AP", "type": "recommended", "evidence": [ { "id": "E1BF42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF42" } ] } ], "protein_names": [ { "name": "Meiosis 1 associated protein", "type": "synonym", "evidence": [ { "id": "E1BF42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF42/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BF42", "url": "https://www.uniprot.org/uniprotkb/E1BF42" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "M1AP", "url": "https://www.uniprot.org/uniprotkb/E1BF42", "locus": { "chromosome": "11", "start_pos": 10085634, "end_pos": 9989525, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006988", "url": "https://www.ensembl.org/id/ENSBTAG00000006988" } ] } } ], "crossref": [ { "id": "E1BF42", "url": "https://alphafold.ebi.ac.uk/entry/E1BF42", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006988", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006988", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "541185", "url": "https://www.ncbi.nlm.nih.gov/gene/541185", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541185", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541185", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LRKHPCK", "url": "https://omabrowser.org/oma/group/LRKHPCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR28642", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28642", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28642:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28642:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28287", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28287", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9THU5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THU5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF42", "url": "https://www.uniprot.org/uniprotkb/E1BF42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF42-1", "url": "https://www.uniprot.org/uniprotkb/E1BF42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHHGQMASKRPSNPTQMYQQPPRLLIVHIALPSWANVCSNLCEALQNFFSLACSLMGPSRIPLFSLYIVQNQHECILPFVQVKGNFARLQACISELRMLQREGCFRPQGTSLQLAIEDGLQQFKQYSRHMSTGAALTYSSLEITVLTSQPGKEVVKQLEEGLKDTDLVRIRKLQVVEITKGVLECMNSASPVEEPSNEESSVLATDIDLQTIDSDIVSMEIFFKAWLHNSGTDQEHIHLLLPSRSISNISRTRDDSMCLKCDLQERLLSPSLLPGTADGSLRMDDPKGDFSTLYQMVSQSPASCYKLRVIKALKSSGVCESLTYGLPFILRPTSCWRLEWDELETNQQHFHALCHSLLKREWLLLAKGEPLNREHKLREPASTFYVILPSHSPTLLVKAVATRELMLPSPFPLLPEDMPADSLKTVESMLDDLELESTYNPLEVWSHLYSHLSSTFANPHGRFHPSSKSRAVRKHPYKAQPLQINRVRATVAPLPMTPAPGRGPKMPAASKASSEVFFQPPMEEKEEEEAEEEYPLGP", "length": 538, "header": "tr|E1BF42-1|E1BF42_BOVIN Isoform 1 of Meiosis 1 associated protein OS=Bos taurus OX=9913 GN=M1AP PE=4 SV=3 CANONICAL=E1BF42-1" }, "isoforms": [ { "isoform_ac": "A0AAA9THU5-1", "url": "https://www.uniprot.org/uniprotkb/E1BF42/entry#A0AAA9THU5-1", "sequence": { "sequence": "MHHGQMASKRPSNPTQMYQQPPRLLIVHIALPSWANVCSNLCEALQNFFSLACSLMGPSRIPLFSLYIVQNQHECILPFVQVKGNFARLQACISELRMLQREGCFRPQGTSLQLAIEDGLQQFKQYSRHMSTGAALTYSSLEITVLTSQPGKEVVKQLEEGLKDTDLVRIRKLQVVEITKGVLECMNSASPVEEPSNEESSVLATDIDLQTIDSDIVSMEIFFKAWLHNSGTDQEHIHLLLPSRSISNISRTRDDSMCLKCDLQERLLSPSLLPGTADGSLRMDDPKGDFSTLYQMVSQSPASCYKLRVIKALKSSGVCESLTYGLPFILRPTSCWRLEWDELETNQQHFHALCHSLLKREWLLLAKGEPLNREHKLREPASTFYVILPSHSPTLLVKAVATRELMLPSPFPLLPEDMPADSLKTVESMLDDLELESTYNPLEVWSHLYSHLSSTFANPHGRFHPSSKSRAVRKAQPLQINRVRATVAPLPMTPAPGRGPKMPAASKASSEVFFQPPMEEKEEEEAEEEYPLGP", "length": 534, "header": "tr|A0AAA9THU5-1|E1BF42_BOVIN Computationally mapped isoform of Meiosis 1 associated protein OS=Bos taurus OX=9913 GN=M1AP PE=4 SV=1 CANONICAL=E1BF42-1" }, "locus": { "chromosome": "11", "start_pos": 10084630, "end_pos": 9993594, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092915.1", "url": "https://www.ensembl.org/id/ENSBTAT00000092915.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095774.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095774.1" } ] } }, { "isoform_ac": "E1BF42-1", "url": "https://www.uniprot.org/uniprotkb/E1BF42/entry#E1BF42-1", "sequence": { "sequence": "MHHGQMASKRPSNPTQMYQQPPRLLIVHIALPSWANVCSNLCEALQNFFSLACSLMGPSRIPLFSLYIVQNQHECILPFVQVKGNFARLQACISELRMLQREGCFRPQGTSLQLAIEDGLQQFKQYSRHMSTGAALTYSSLEITVLTSQPGKEVVKQLEEGLKDTDLVRIRKLQVVEITKGVLECMNSASPVEEPSNEESSVLATDIDLQTIDSDIVSMEIFFKAWLHNSGTDQEHIHLLLPSRSISNISRTRDDSMCLKCDLQERLLSPSLLPGTADGSLRMDDPKGDFSTLYQMVSQSPASCYKLRVIKALKSSGVCESLTYGLPFILRPTSCWRLEWDELETNQQHFHALCHSLLKREWLLLAKGEPLNREHKLREPASTFYVILPSHSPTLLVKAVATRELMLPSPFPLLPEDMPADSLKTVESMLDDLELESTYNPLEVWSHLYSHLSSTFANPHGRFHPSSKSRAVRKHPYKAQPLQINRVRATVAPLPMTPAPGRGPKMPAASKASSEVFFQPPMEEKEEEEAEEEYPLGP", "length": 538, "header": "tr|E1BF42-1|E1BF42_BOVIN Isoform 1 of Meiosis 1 associated protein OS=Bos taurus OX=9913 GN=M1AP PE=4 SV=3 CANONICAL=E1BF42-1" }, "locus": { "chromosome": "11", "start_pos": 10084630, "end_pos": 9993594, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009183.5", "url": "https://www.ensembl.org/id/ENSBTAT00000009183.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009183.5", "url": "https://www.ensembl.org/id/ENSBTAP00000009183.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 497, "start_aa": "Thr", "end_pos": 497, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr497", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:541185", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541185", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XN48-1", "protein_name": "Meiosis 1 associated protein", "gene_name": "M1AP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHIRYQCTEDMNSRKLLSETRRTFPPTKARCQQPSRILIVDVTSPSWANTCSVLSEALENSLCLACSLTGPSRIPLLSLYLVQNQQECLLPFVHLKENFARVQACISELRSLSREGCFPQGGNGVVQAVQDGLQQFKQYSRHTAAGGSANSSVEITILTSQSGKEIVKQLERKLKDVDLVSLRRIQVIEVLKRDFLEPEDVEQCIPAEEPSSSDIAILGMDIDLQTIEDNVISLEMLFKTWLHDCGSEREHLHLLLPSGGLSCGTAPKPTLMCLKCDLQERLLDPNLLSGTTDGTLRTADLNSPCQMTAWPATMLYKLQVVKALKSEGVCESVLYGLPFIIKPTSCWQLDWDELELNQHSFHALCHSLLKRKWMLLAKHEPQNTCPSWNVVVHSYYIIVPSDSATLLVKPVAVRELLMPSDFPALLAEHPERVQSPIESALNSLEVEVTYNPLYLKSNLYKYLKSMLYRPLHRQQPQPRDQRAERHQPKQVRPSSLTNIDRHYLVLLICFLQKGRGQFPDTLMGQGGQHMTGAAFTYSCRSREVSIACAVEEIGAEHLTHANTMRQHAVKRWTS", "length": 574 }, "evidence": [ { "id": "E1BF42", "url": "https://omabrowser.org/oma/group/E1BF42/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZVK0-1", "protein_name": "Meiosis 1 associated protein", "gene_name": "M1ap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHRRRTTSRGTSPATKISHQPPRLLIVHIAVPSWDDICPNLCEALQNFFSIACSLMGPSRMSLFSLYTVQNQHECVLPFVQVRGNFVRLQACISELRTLQVEGCYRPSHTLLPLAVEDGLQQFKQYSSHMATSAAQPLTSLEITVLTSQPGKEVVKELEEGLKDINLLSVRRLQVVEVTKGIQEHTDSPSPIEEPSNDESSILEADIVLETLDNDVVSMEVFFKAWLHNTETDQENIHLFLTPQSLPPSSRAKDNPICLKCDLQERFLSPSLLPGTADSMSRIDDPKGDISTIYQMASLSSDSPYKLQVIKALKSSGICESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHCLMKRDWLLLARGEPLIPRHNQSLPACSFYVITPSHSLTLLVKLVATRELMLPGFFPLLSEDPPEDSLKIIESTLDSLELGLTYNPLQVGSHLYSHLSSAHAKPQGRPYTSWAGRGLRKGDQLQTNRARAPVVPLPVTPVPGRALKKSAASKAASGTFLPSDSEDEYPSQT", "length": 526 }, "evidence": [ { "id": "E1BF42", "url": "https://omabrowser.org/oma/group/E1BF42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TC57-1", "protein_name": "Meiosis 1 arrest protein", "gene_name": "M1AP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHPGRTTGKGPSTHTQIDQQPPRLLIVHIALPSWADICTNLCEALQNFFSLACSLMGPSRMSLFSLYMVQDQHECILPFVQVKGNFARLQTCISELRMLQREGCFRSQGASLRLAVEDGLQQFKQYSRHVTTRAALTYTSLEITILTSQPGKEVVKQLEEGLKDTDLARVRRFQVVEVTKGILEHVDSASPVEDTSNDESSILGTDIDLQTIDNDIVSMEIFFKAWLHNSGTDQEQIHLLLSSQCFSNISRPRDNPMCLKCDLQERLLCPSLLAGTADGSLRMDDPKGDFITLYQMASQSSASHYKLQVIKALKSSGLCESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHSLLKREWLLLAKGEPPGPGHSQRIPASTFYVIMPSHSLTLLVKAVATRELMLPSTFPLLPEDPHDDSLKNVESMLDSLELEPTYNPLHVQSHLYSHLSSIYAKPQGRLHPHWESRAPRKHPCKTGQLQTNRARATVAPLPMTPVPGRASKMPAASKSSSDAFFLPSEWEKDPSRP", "length": 530 }, "evidence": [ { "id": "E1BF42", "url": "https://omabrowser.org/oma/group/E1BF42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z0E1-1", "protein_name": "Meiosis 1 arrest protein", "gene_name": "M1ap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRRKTTSRGTSAAMKISHQPPRLLIVNIAVPSWVDICPNLCEALQNFFSIACSLMGPSRMSLFSLYTVQNQHECVLPFVQVRGNFIRLQACISELRMLQVEGCHRPPHALLPLAIEDGLQQFKQYSSHMASSAAQPWTSLEITVLTSRPGKEVVKELEEGLKDINLLSVRRLQVAEVTKGIQERSDSPSPTEEPSNDESSILEADIVLETLDNDVVSMEVFFKAWLHNSETDQENIHLLLTPQSLPPPSRAKDHPICLKCDLQERFLSPSLLPGTADGVSRIDDPKGDISTLYQMASLASASPYKLQVVKALKSSGICESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHCLLKRDWLLLARGEPLIHKHNQSLPACSFYVITPSHSLTLLVKLVATRELMLPGFFPLLSEDPPEDSLKIIESTLDSLDLGLTYNPLHVGSHLYSHLSSAHAKPQGRLYTSCASRGLRKGGQLQTNRVRAAVVPLPVAPAPRRALKMTAASKASSAAFLPSDSEEGEEERPSHT", "length": 529 }, "evidence": [ { "id": "E1BF42", "url": "https://omabrowser.org/oma/group/E1BF42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "E1BF42", "url": "https://www.uniprot.org/uniprotkb/E1BF42" } ], "pmid": "" }, { "name": "meiosis I", "id": "GO:0007127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007127", "evidence": [ { "database": "UniProtKB", "id": "E1BF42", "url": "https://www.uniprot.org/uniprotkb/E1BF42" } ], "pmid": "" }, { "name": "female gamete generation", "id": "GO:0007292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007292", "evidence": [ { "database": "UniProtKB", "id": "E1BF42", "url": "https://www.uniprot.org/uniprotkb/E1BF42" } ], "pmid": "" }, { "name": "male meiosis chromosome separation", "id": "GO:0051308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051308", "evidence": [ { "database": "UniProtKB", "id": "E1BF42", "url": "https://www.uniprot.org/uniprotkb/E1BF42" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BF42", "url": "https://www.uniprot.org/uniprotkb/E1BF42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BF42", "url": "https://www.uniprot.org/uniprotkb/E1BF42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BF42-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 538, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BF42-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BF42" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 497 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 248, "end_pos": 250 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEH8-1", "uniprot_ac": "E1BEH8", "uniprot_id": "E1BEH8_BOVIN", "mass": { "chemical_mass": 37358.0, "monoisotopic_mass": 37358.0 }, "refseq": { "ac": "NP_001179870", "name": "nucleotide sugar transporter SLC35B4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179870" }, "gene_names": [ { "name": "SLC35B4", "type": "recommended", "evidence": [ { "id": "E1BEH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEH8" } ] }, { "name": "SLC35B4", "type": "synonym", "evidence": [ { "id": "NP_001179870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179870" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member B4", "type": "recommended", "evidence": [ { "id": "E1BEH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEH8/entry#names_and_taxonomy" } ] }, { "name": "nucleotide sugar transporter SLC35B4", "type": "synonym", "evidence": [ { "id": "NP_001179870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179870" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEH8", "url": "https://www.uniprot.org/uniprotkb/E1BEH8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC35B4", "url": "https://www.uniprot.org/uniprotkb/E1BEH8", "locus": { "chromosome": "4", "start_pos": 97915117, "end_pos": 97975226, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003372", "url": "https://www.ensembl.org/id/ENSBTAG00000003372" } ] } } ], "crossref": [ { "id": "E1BEH8", "url": "https://alphafold.ebi.ac.uk/entry/E1BEH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003372", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003372", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613784", "url": "https://www.ncbi.nlm.nih.gov/gene/613784", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613784", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613784", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NPFTGWH", "url": "https://omabrowser.org/oma/group/NPFTGWH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEH8", "url": "https://www.orthodb.org/?gene=E1BEH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10778", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10778", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10778:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10778:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08449", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08449", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-727802", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-727802", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179870", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179870", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TJ75", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJ75-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPY1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPY1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEH8", "url": "https://www.uniprot.org/uniprotkb/E1BEH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BEH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPAFAVGLVFAGCCSNVIFLELLARKHPGCGNIVTFAQFLFIAVEGFLFEADLGRKRPAIPIRYYAVMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIFKYTSIALVSVGIFVCTFMSAKQVTSQSSSTENDGFQAFAWWLLGIGALTFALLMSARMGIFQETLYKQFGKHSKEALFYNHALPLPGFIFLASDIYDHAVLFNNSELYQVPVVGVTVPIMWFYLLMNVITQYVCIRGVFILTTECASLTVTLVVTLRKFVSLIFSILYFQNPFTLWHWLGTLFVFIGTLMYTEVWNNLGATKGQPQKEEKKN", "length": 331, "header": "tr|E1BEH8-1|E1BEH8_BOVIN Isoform 1 of Solute carrier family 35 member B4 OS=Bos taurus OX=9913 GN=SLC35B4 PE=3 SV=1 CANONICAL=E1BEH8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TJ75-1", "url": "https://www.uniprot.org/uniprotkb/E1BEH8/entry#A0AAA9TJ75-1", "sequence": { "sequence": "MRPAFAVGLVFAGCCSNVIFLELLARKHPGCGNIVTFAQFLFIAVEGFLFEADLGRKRPAIPIRYYAVMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIFKYTSIALVSVGIFVCTFMSAKQVTSQSSSTENDGFQAFAWWLLGIGALTFALLMSARMGIFQETLYKQFGKHSKEALFYNHALPLPGFIFLASDIYDHAVLFNNSELYQVPVVGVTVPIMWFYLLMNVITQYVCIRGVFILTTECASLTVTLVVTLRKITWRFTYLSHSAFYQTPSISIKCFQSPLPFKCLGAVSKAPQCLPCTVVGHFTTVVSNLSSAAWQLGQSQTTSPATGSRPDTTEAT", "length": 362, "header": "tr|A0AAA9TJ75-1|E1BEH8_BOVIN Computationally mapped isoform of Solute carrier family 35 member B4 OS=Bos taurus OX=9913 GN=SLC35B4 PE=3 SV=1 CANONICAL=E1BEH8-1" }, "locus": { "chromosome": "4", "start_pos": 97974922, "end_pos": 97915244, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128350.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128350.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098501.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098501.1" } ] } }, { "isoform_ac": "A0AAA9TPY1-1", "url": "https://www.uniprot.org/uniprotkb/E1BEH8/entry#A0AAA9TPY1-1", "sequence": { "sequence": "MGYENADKDGQKHPGCGNIVTFAQFLFIAVEGFLFEADLGRKRPAIPIRYYAVMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIFKYTSIALVSVGIFVCTFMSAKQVTSQSSSTENDGFQAFAWWLLGIGALTFALLMSARMGIFQETLYKQFGKHSKEALFYNHALPLPGFIFLASDIYDHAVLFNNSELYQVPVVGVTVPIMWFYLLMNVITQYVCIRGVFILTTECASLTVTLVVTLRKFVSLIFSILYFQNPFTLWHWLGTLFVFIGTLMYTEVWNNLGATKGQPQKEEKKN", "length": 316, "header": "tr|A0AAA9TPY1-1|E1BEH8_BOVIN Computationally mapped isoform of Solute carrier family 35 member B4 OS=Bos taurus OX=9913 GN=SLC35B4 PE=3 SV=1 CANONICAL=E1BEH8-1" }, "locus": { "chromosome": "4", "start_pos": 97956227, "end_pos": 97939645, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114344.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114344.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100624.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100624.1" } ] } }, { "isoform_ac": "E1BEH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BEH8/entry#E1BEH8-1", "sequence": { "sequence": "MRPAFAVGLVFAGCCSNVIFLELLARKHPGCGNIVTFAQFLFIAVEGFLFEADLGRKRPAIPIRYYAVMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIFKYTSIALVSVGIFVCTFMSAKQVTSQSSSTENDGFQAFAWWLLGIGALTFALLMSARMGIFQETLYKQFGKHSKEALFYNHALPLPGFIFLASDIYDHAVLFNNSELYQVPVVGVTVPIMWFYLLMNVITQYVCIRGVFILTTECASLTVTLVVTLRKFVSLIFSILYFQNPFTLWHWLGTLFVFIGTLMYTEVWNNLGATKGQPQKEEKKN", "length": 331, "header": "tr|E1BEH8-1|E1BEH8_BOVIN Isoform 1 of Solute carrier family 35 member B4 OS=Bos taurus OX=9913 GN=SLC35B4 PE=3 SV=1 CANONICAL=E1BEH8-1" }, "locus": { "chromosome": "4", "start_pos": 97974922, "end_pos": 97939645, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004376.6", "url": "https://www.ensembl.org/id/ENSBTAT00000004376.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004376.4", "url": "https://www.ensembl.org/id/ENSBTAP00000004376.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:613784", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613784", "resource": "KEGG Pathway" }, { "id": "R-BTA-727802", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-727802", "resource": "Reactome", "description": "Transport of nucleotide sugars" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FIJ1-1", "protein_name": "Solute carrier family 35 member B4", "gene_name": "SLC35B4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHPAFAVGLVFAGCCSNVVFLELLARKHPGCGNIVTFAQFLFIAVEGFLFEADLGRKRPAIPIRYYGAMVAMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIFKYTSIALVSVGIFICTFMSAKQVTSQSSSSENDGFQAFAWWLLGIGALTFALLMSARMGIFQETLYRQFGKHSKEALFYNHALPLPGFIFLASDIYDHAVLFNKSELYQVPVVGVTVPIMWFYLLMNVITQYVCIRGVFTLTTECTSLTVTLVVTLRKFVSLIFSILYFRNPFTLWHWLGTVFVFLGTLMYTEVWSNLGPPKGQPPKEDKRN", "length": 331 }, "evidence": [ { "id": "E1BEH8", "url": "https://omabrowser.org/oma/group/E1BEH8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZAN4-1", "protein_name": "Solute carrier family 35 member B4", "gene_name": "Slc35b4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPAFAVGLVFAGCCSNVIFLELLARTHPGCGNIVTFAQFLFIAVEGFLFEADLGRKPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSMFKYTSIALVSAGIFICTFMSAKQVTVQSSLSDKDGFQAFAWWLLGIGALTFALLMSARMGIFQETLYRQFGKHSKEALFYNHALPLPGFIFLASDIYDHVVLFNKSELYQVPVLGVTVPIMWFYLLMNVVTQYVCIRGVFILTTECSSLTVTLVVTLRKFVSLIFSILYFQNQFTLWHWLGTVFVFTGTLMYTEVWKNLGATKSQLQKDDKKD", "length": 331 }, "evidence": [ { "id": "E1BEH8", "url": "https://omabrowser.org/oma/group/E1BEH8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P40004-1", "protein_name": "UDP-N-acetylglucosamine transporter YEA4", "gene_name": "YEA4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MWNSLKAFALVFGGCCSNVITFETLMSNETGSINNLITFCQFLFVTCQGLPEFLDVHQPFPYFKPLKTPLHVYVITVVLFYISSTTNNNVFKYNISIPIHIVFRCFGTVITMFTCWLLNGRKYTKIQILSTLFLTIGAIIASLFKDADFRYQDLKLQAWKIGSDQSVDLTFIFGICILVLSSFTSSLLSAYNERTYQKYGKHWKENIFYSHFLSLPLFLFSRKQLIHEYRVMRKSERILCSNFGGKILVPREETLLLFNVLTQYFCVKGVNILASKTNALTLSITLLVRKFISLLLSVRLFDNNLSYTGYIGVYLVFFGAFIYSLGSIHPRQNDKGAIKKSK", "length": 342 }, "evidence": [ { "id": "E1BEH8", "url": "https://omabrowser.org/oma/group/E1BEH8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7ZW46-1", "protein_name": "UDP-xylose and UDP-N-acetylglucosamine transporter", "gene_name": "slc35b4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNTLFAVTLVFVGCCSNVVFLELLVRDFPGCGNIVTFAQFAFIALEGFIFETNFGRKKPQIPLSNYVIMVTMFFTVSVINNYALDFNIAMPLHMIFRSGSLIANMILGIIILKNRYSMSKYLSIVLVSVGIFICTIMSAKQVNVEKGGTEEDGVYAFMHWLLGIAMLTFALLMSARMGIFQETLYKKYGKHSKEALFYNHCLPLPGFLLLSTNIYNHAVLFSQSPPMEVPVIGLSMPVMWFYLLMNVITQYVCIRGVFILTTECASLTVTLVVTLRKFLSLIISILYFQNPFTAWHWVGTAVVFLGTLLYTEVLSSIPAAFKGYKVDKKAE", "length": 331 }, "evidence": [ { "id": "E1BEH8", "url": "https://omabrowser.org/oma/group/E1BEH8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CIA5-1", "protein_name": "Nucleotide sugar transporter SLC35B4", "gene_name": "Slc35b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPAFAVGLVFAGCCSNVIFLELLARTHPGCGNIVTFAQFLFIAVEGFLFEANLGRKPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSMFKYTSIALVSAGIFICTFMSAKQVTVQTGLSDKDGFQAFAWWLLGIAALTFALLMSARMGIFQETLYRQFGKHSKEALFYNHALPLPGFIFLASDIYDHVVLFNKSELYQVPVIGVTMPVMWFYLLMNVVTQYVCIRGVFILTTECTSLTVTLVVTLRKFVSLIFSILYFQNQFTMWHWLGTSFVFIGTLMYTEVWKNLGTTKSELQKDDKKD", "length": 331 }, "evidence": [ { "id": "E1BEH8", "url": "https://omabrowser.org/oma/group/E1BEH8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q969S0-1", "protein_name": "Nucleotide sugar transporter SLC35B4", "gene_name": "SLC35B4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPALAVGLVFAGCCSNVIFLELLARKHPGCGNIVTFAQFLFIAVEGFLFEADLGRKPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIFKYTSIALVSVGIFICTFMSAKQVTSQSSLSENDGFQAFVWWLLGIGALTFALLMSARMGIFQETLYKRFGKHSKEALFYNHALPLPGFVFLASDIYDHAVLFNKSELYEIPVIGVTLPIMWFYLLMNIITQYVCIRGVFILTTECASLTVTLVVTLRKFVSLIFSILYFQNPFTLWHWLGTLFVFIGTLMYTEVWNNLGTTKSEPQKDSKKN", "length": 331 }, "evidence": [ { "id": "E1BEH8", "url": "https://omabrowser.org/oma/group/E1BEH8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W429-1", "protein_name": "Endoplasmic reticulum GDP-fucose transporter", "gene_name": "Efr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALNLKALLGMLFVFIGCCSNVVFLELIIQIDPGAGNLITFAQFLFIALEGLVFTSKFFTVRPKIALKDYVILVALFFGANVCNNYAFNFNIPMPLHMIFRSGSLMANMIMGIVLLKKRYNLRQYSSVAMITAGIILCTLVSSGDVKDNTHHSLKVDTSYSDFFWWTVGIGLLTIALLVTAYMGIYQEVIYKKYGKHPSEALFFTHMLPLPGFLIMAGNIVQHFGIAWSSEPVAVPLLGAIGLEWKFPLMLFYLLCNVVTQYVCISAVYVLTTECASLTVTLVVTLRKFVSLLFSIIYFRNPFTLNHWVGTILVFFGTILFANVINQVRDAYRARSSRKTHFDTAPLAKKVE", "length": 352 }, "evidence": [ { "id": "E1BEH8", "url": "https://omabrowser.org/oma/group/E1BEH8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BEH8", "url": "https://www.uniprot.org/uniprotkb/E1BEH8" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BEH8", "url": "https://www.uniprot.org/uniprotkb/E1BEH8" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "E1BEH8", "url": "https://www.uniprot.org/uniprotkb/E1BEH8" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BEH8", "url": "https://www.uniprot.org/uniprotkb/E1BEH8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BEH8", "url": "https://www.uniprot.org/uniprotkb/E1BEH8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "UDP-N-acetylglucosamine transmembrane transporter activity", "id": "GO:0005462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005462", "evidence": [ { "database": "UniProtKB", "id": "E1BEH8", "url": "https://www.uniprot.org/uniprotkb/E1BEH8" } ], "pmid": "" }, { "name": "UDP-xylose transmembrane transporter activity", "id": "GO:0005464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005464", "evidence": [ { "database": "UniProtKB", "id": "E1BEH8", "url": "https://www.uniprot.org/uniprotkb/E1BEH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "E1BEH8", "url": "https://www.uniprot.org/uniprotkb/E1BEH8" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine transmembrane transport", "id": "GO:1990569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990569", "evidence": [ { "database": "UniProtKB", "id": "E1BEH8", "url": "https://www.uniprot.org/uniprotkb/E1BEH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEH8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 331, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEH8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEH8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIH3-1", "uniprot_ac": "E1BIH3", "uniprot_id": "E1BIH3_BOVIN", "mass": { "chemical_mass": 35132.0, "monoisotopic_mass": 35132.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Lck interacting transmembrane adaptor 1", "type": "synonym", "evidence": [ { "id": "E1BIH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIH3", "url": "https://www.uniprot.org/uniprotkb/E1BIH3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BIH3", "locus": {} } ], "crossref": [ { "id": "E1BIH3", "url": "https://alphafold.ebi.ac.uk/entry/E1BIH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007501", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007501", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR026072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GTCGART", "url": "https://omabrowser.org/oma/group/GTCGART/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIH3", "url": "https://www.orthodb.org/?gene=E1BIH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47740:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47740:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TK52", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TK52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TK52-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TK52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIH3", "url": "https://www.uniprot.org/uniprotkb/E1BIH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIH3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRHRSGAVRWVPSPPVPQPPAPVFSLQARPHLHRMRLQGSSVPPALWVLGCLTLLLWLWVLCTTCNRKQARRQPSRLQGSAMPAEVSLLRRPHCSLSKSDTRLHELHRSRPCSRAPRPASMDLLRPQWLEASRGITRPPTPFSHQELPLAAPSTGPEATYSNVGLATIPRARLAVSSGVWAGARLTSSYARPGPEARPVVAEYACVQKFRGTDRGPQGLGQGKVEAIPPTQVDILYSRVNKPKRRDPGPATDQPDPKGGGAILALGSDPAYEVLPLGGLGMDKSLLENVYESIQEMGAPLEPPSSSSYQERTCAGHRDTLLPV", "length": 323, "header": "tr|E1BIH3-1|E1BIH3_BOVIN Isoform 1 of Lck interacting transmembrane adaptor 1 OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=E1BIH3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TK52-1", "url": "https://www.uniprot.org/uniprotkb/E1BIH3/entry#A0AAA9TK52-1", "sequence": { "sequence": "MRHRSGAVRWVPSPPVPQPPAPVFSLQARPHLHRMRLQGSSVPPALWVLGCLTLLLWLWVLCTTCNRKQARRQPSRLQGSAMPAEVSLLRRPHCSLSKSDTRLHELHRSRPCSRAPRPASMDLLRPQWLEASRGITRPPTPFSHQELPLAAPSTGPEATYSNVGLATIPRARLAVSSGVWAGARLTSSYARPGPEARPVVAEYACVQKFRGTDRGPQGLGQGKVEAIPPTQVDILYSRVNKPKRRDPGPATDQPDPKASPPHATDNTNSRRQRCQHVGSPGSWLPCPLQGRLSIK", "length": 295, "header": "tr|A0AAA9TK52-1|E1BIH3_BOVIN Computationally mapped isoform of Lck interacting transmembrane adaptor 1 OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=E1BIH3-1" }, "locus": { "chromosome": "13", "start_pos": 54036045, "end_pos": 54034417, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108563.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108563.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098747.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098747.1" } ] } }, { "isoform_ac": "E1BIH3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIH3/entry#E1BIH3-1", "sequence": { "sequence": "MRHRSGAVRWVPSPPVPQPPAPVFSLQARPHLHRMRLQGSSVPPALWVLGCLTLLLWLWVLCTTCNRKQARRQPSRLQGSAMPAEVSLLRRPHCSLSKSDTRLHELHRSRPCSRAPRPASMDLLRPQWLEASRGITRPPTPFSHQELPLAAPSTGPEATYSNVGLATIPRARLAVSSGVWAGARLTSSYARPGPEARPVVAEYACVQKFRGTDRGPQGLGQGKVEAIPPTQVDILYSRVNKPKRRDPGPATDQPDPKGGGAILALGSDPAYEVLPLGGLGMDKSLLENVYESIQEMGAPLEPPSSSSYQERTCAGHRDTLLPV", "length": 323, "header": "tr|E1BIH3-1|E1BIH3_BOVIN Isoform 1 of Lck interacting transmembrane adaptor 1 OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=E1BIH3-1" }, "locus": { "chromosome": "13", "start_pos": 54036045, "end_pos": 54034630, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009867.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009867.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009867.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009867.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FKT8-1", "protein_name": "Lck interacting transmembrane adaptor 1", "gene_name": "LIME1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPQGSSASPALWVLGCLTLLLWLWVLCTACHRRRAGRQVSRLQGMQGGGMPTKAVSARYPQGHAGAGRGLTGRPCPQSLLRPPHLCSLSKSDTRLHELCRGQPCSRAPRPASVDLLCPQWLEVSRGKTRPPEAFSLQELPAAVPFTDPEATYSNVGLAVIPRARLAFGSGVWVGAHSCARLGPEARPVASEYACIQKLKGTGQVPQGLGQGRAEVIPANQVDSLYSKVSKPKRRDPGPASDQPDPKGGGTVLALGGDLAYDALPPKSVGVNGSFLENVYESIQEMGGPGASKL", "length": 294 }, "evidence": [ { "id": "E1BIH3", "url": "https://omabrowser.org/oma/group/E1BIH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A1E8-1", "protein_name": "Lck interacting transmembrane adaptor 1", "gene_name": "Lime1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPPVPSAPLALWVLGCFSLLLWLWALCTACHRKRAQRQQTGLQGSLMPVEVPLLRQAHLCSLSKSDTRLHELHRGQRSTIAPRPASMDLLHPRWLELSRGSTRSQVPNSAFPPRQLPRAPPAAPATPPSTSPEATYSNVGLAAIPRASLAASPVVWPGRQLTISCTRLGPGAEYACIQKHKGTEQGCQESQQKAKVTPATQMDVLYSRVCKPKRRDPRPDTDQLNLQDGRTILALGNDVKYEAITLRGQDMKQGTLENVYESIKEMGL", "length": 269 }, "evidence": [ { "id": "E1BIH3", "url": "https://omabrowser.org/oma/group/E1BIH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9EQR5-1", "protein_name": "Lck-interacting transmembrane adapter 1", "gene_name": "Lime1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPPVPSAPLALWVLGCFSLLLWLWALCTACHRKRAQRQQTGLQDSLVPVEMPLLRQTHLCSLSKSDTRLHELHRGPRSSIAPRPASMDLLHPRWLEMSRGSTRSQVPNSAFPPRQLPRAPPAAPATAPSTSSEATYSNVGLAAIPRASLAASPVVWAGTQLTISCARLGPGAEYACIQKHKGTEQGCQELQQKAKVIPATQMDVLYSRVCKPKRRDPRPVTDQLNLQDGRTSLPLGSDVEYEAINLRGQDMKQGPLENVYESIKEMGL", "length": 269 }, "evidence": [ { "id": "E1BIH3", "url": "https://omabrowser.org/oma/group/E1BIH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H400-1", "protein_name": "Lck-interacting transmembrane adapter 1", "gene_name": "LIME1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLPVSWAPPALWVLGCCALLLSLWALCTACRRPEDAVAPRKRARRQRARLQGSATAAEASLLRRTHLCSLSKSDTRLHELHRGPRSSRALRPASMDLLRPHWLEVSRDITGPQAAPSAFPHQELPRALPAAAATAGCAGLEATYSNVGLAALPGVSLAASPVVAEYARVQKRKGTHRSPQEPQQGKTEVTPAAQVDVLYSRVCKPKRRDPGPTTDPLDPKGQGAILALAGDLAYQTLPLRALDVDSGPLENVYESIRELGDPAGRSSTCGAGTPPASSCPSLGRGWRPLPASLP", "length": 295 }, "evidence": [ { "id": "E1BIH3", "url": "https://omabrowser.org/oma/group/E1BIH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "E1BIH3", "url": "https://www.uniprot.org/uniprotkb/E1BIH3" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "E1BIH3", "url": "https://www.uniprot.org/uniprotkb/E1BIH3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E1BIH3", "url": "https://www.uniprot.org/uniprotkb/E1BIH3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "B cell receptor complex", "id": "GO:0019815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019815", "evidence": [ { "database": "UniProtKB", "id": "E1BIH3", "url": "https://www.uniprot.org/uniprotkb/E1BIH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIH3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 323, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIH3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIH3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BL26-1", "uniprot_ac": "E1BL26", "uniprot_id": "E1BL26_BOVIN", "mass": { "chemical_mass": 148289.0, "monoisotopic_mass": 148289.0 }, "refseq": { "ac": "NP_001179993", "name": "E3 ubiquitin-protein ligase RNF123", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179993" }, "gene_names": [ { "name": "RNF123", "type": "recommended", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] }, { "name": "RNF123", "type": "synonym", "evidence": [ { "id": "NP_001179993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179993" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF123", "type": "recommended", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase RNF123", "type": "synonym", "evidence": [ { "id": "NP_001179993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179993" } ] }, { "name": "Kip1 ubiquitination-promoting complex protein 1", "type": "synonym", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26/entry#names_and_taxonomy" } ] }, { "name": "RING finger protein 123", "type": "synonym", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RNF123", "url": "https://www.uniprot.org/uniprotkb/E1BL26", "locus": { "chromosome": "22", "start_pos": 50483447, "end_pos": 50511880, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011588", "url": "https://www.ensembl.org/id/ENSBTAG00000011588" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011588", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011588", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12882", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12882", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16541", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16541", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514160", "url": "https://www.ncbi.nlm.nih.gov/gene/514160", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514160", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514160", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BL26", "url": "https://www.orthodb.org/?gene=E1BL26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13363:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13363:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179993", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179993", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TM68", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TM68-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQN9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQN9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM67", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM67-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL26-1", "url": "https://www.uniprot.org/uniprotkb/E1BL26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKEGGMAFSRKSYKLTSDAERSRVTGIVHEKLLSDYLHRVFASPDHRPAAATSRKPLNFQNLPEHLDQLLHVDDKEDEESQEQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWIYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDEGTLSFSLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPLQDPPSTSLVRAQRLLGCFRAVLSMELDPVEGRLVEKESSEWQLQGQPTVLLTLAHIFHHFAPLLCEVYVVEAVLMSFLLGVVEAGPPEQAQTVVHHVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLSLQIHYLRLTIAILSHEKSRKFLLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHRSPREGKEEVREETSEERLRRRAYERGCQRLKKRIEVVEELQVQILKLLLNNKDNNGGEASRYIFLTKFRKFLQENASGRGNTPMLCPPEYMVCFLHRLISALRFYWDEYKASKPRTSFSEEAYVPPQIFYNGKVDYFDLQRLGGLLSHLRKTLKDDLASKANILIDPMELQATTMDDLDEDEEPAPAAAQRPMQALAVGGALPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSASEKVKVRTLSAEQRTREDIEGSQWNEGLLVGRPPEEPEHPLTENSLLEVLDGVVMMYNLSVHQQLGKMVGVSDDVNEYAMALRDTEDKLRRCPKRRKDILAELSKSQKVFSEKLDHLSRRLAWVHAAVYSQEKMQDIYWLLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRLAAILAKHFADTRIVGTDIRDSLMQALASYVCYPNSLRAVERIPEEQRIAMVRNLLAPYEQRPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKPEDASLPSLQKPCPSTLLQQHMADLLREGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVSLLRVLEMTITLVPEIFLDWARPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGLESVDHYPILVAVTGILVRLLVHGPASGTERATSVLLADPCFQLRSISYLLGQPEPPAPGTALPAPDRKHFSLQSYTDYINVEELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAHPISAVFQPCGHKSCKACIDQHLMNNKDCFFCKATIVSVEDWDKAAHASATSSAA", "length": 1313, "header": "tr|E1BL26-1|E1BL26_BOVIN Isoform 1 of E3 ubiquitin-protein ligase RNF123 OS=Bos taurus OX=9913 GN=RNF123 PE=4 SV=4 CANONICAL=E1BL26-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TM68-1", "url": "https://www.uniprot.org/uniprotkb/E1BL26/entry#A0AAA9TM68-1", "sequence": { "sequence": "MASKEGGMAFSRKSYKLTSDAERSRVTGIVHEKLLSDYLHRVFASPDHRPAAATSRKPLNFQNLPEHLDQLLHVDDKEDEESQEQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWIYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDEGTLSFSLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPLQDPPSTSLVRAQRLLGCFRAVLSMELDPVEGRLVEKESSEWQLQGQPTVLLTLAHIFHHFAPLLAGPPEQAQTVVHHVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLSLQIHYLRLTIAILSHEKSRKFLLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHRSPREGKEEVREETSEERLRRRAYERGCQRLKKRIEVVEELQVQILKLLLNNKDNNGGEASRYIFLTKFRKFLQENASGRGNTPMLCPPEYMVCFLHRLISALRFYWDEYKASKPRTSFSEEAYVPPQIFYNGKVDYFDLQRLGGLLSHLRKTLKDDLASKANILIDPMELQATTMDDLDEDEEPAPAAAQRPMQALAVGGALPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSASEKVKVRTLSAEQRTREDIEGSQWNEGLLVGRPPEEPEHPLTENSLLEVLDGVVMMYNLSVHQQLGKMVGVSDDVNEYAMALRDTEDKLRRCPKRRKDILAELSKSQKVFSEKLDHLSRRLAWVHAAVYSQEKMQDIYWLLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRLAAILAKHFADTRIVGTDIRDSLMQALASYVCYPNSLRAVERIPEEQRIAMVRNLLAPYEQRPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKPEDASLPSLQKPCPSTLLQQHMADLLREGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVSLLRVLEMTITLVPEIFLDWARPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGLESVDHYPILVAVTGILVRLLVHGPASGTERATSVLLADPCFQLRSISYLLGQPEPPAPGTALPAPDRKHFSLQSYTDYINVEELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAHPISAVFQPCGHKSCKACIDQHLMNNKDCFFCKATIVSVEDWDKAAHASATSSAA", "length": 1294, "header": "tr|A0AAA9TM68-1|E1BL26_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase RNF123 OS=Bos taurus OX=9913 GN=RNF123 PE=4 SV=1 CANONICAL=E1BL26-1" }, "locus": { "chromosome": "22", "start_pos": 50507304, "end_pos": 50484255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134224.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134224.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097404.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097404.1" } ] } }, { "isoform_ac": "A0AAA9TQN9-1", "url": "https://www.uniprot.org/uniprotkb/E1BL26/entry#A0AAA9TQN9-1", "sequence": { "sequence": "MASKEGGMAFSRKSYKLTSDAERSRVTGIVHEKLLSDYLHRVFASPDHRPAAATSRKPLNFQNLPEHLDQLLHVDDKEDEESQEQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWIYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDEGTLSFSLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPLQDPPSTSLVRAQRLLGCFRAVLSMELDPVEGRLVEKESSEWQLQGQPTVLLTLAHIFHHFAPLLCEVYVVEAVLMSFLLGVVEAGPPEQAQTVVHHVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLSLQIHYLRLTIAILSHEKSRKFLLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHRSPREGKEEVREETSEERLRRRAYERGCQRLKKRIEVVEELQVQILKLLLNNKDNNGGEASRYIFLTKFRKFLQENASGRGNTPMLCPPEYMVCFLHRLISALRFYWDEYKASKPRTSFSEEAYVPPQIFYNGKVDYFDLQRLGGLLSHLRKTLKDDLASKANILIDPMELQATTMDDLDEDEEPAPAAAQRPMQALAVGGALPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSASEKVKVRTLSAEQRTREDIEGSQWNEGLLVGRPPEEPEHPLTENSLLEVLDGVVMMYNLSVHQQLGKMVGVSDDVNEYAMALRDTEDKLRRCPKRRKDILAELSKSQKVFSEKLDHLSRRLAWVHAAVYSQEKMQDIYWLLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRLAAILAKHFADTRIVGTDIRDSLMQALASYVCYPNSLRAVERIPEEQRIAMVRNLLAPYEQRPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKPEDASLPSLQKPCPSTLLQQHMADLLREGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVSLLRVLEMTITLVPEIFLDWARPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGLESVDHYPILVAVTGILVRLLVHGPASGTERATSVLLADPCFQLRSISYLLGQPEPPAPGTALPAPDRKHFSLQSYTDYINVEELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAHPISAVFQPCGHKSCK", "length": 1274, "header": "tr|A0AAA9TQN9-1|E1BL26_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase RNF123 OS=Bos taurus OX=9913 GN=RNF123 PE=4 SV=1 CANONICAL=E1BL26-1" }, "locus": { "chromosome": "22", "start_pos": 50507304, "end_pos": 50484451, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090130.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090130.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099625.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099625.1" } ] } }, { "isoform_ac": "A0ABI0NM67-1", "url": "https://www.uniprot.org/uniprotkb/E1BL26/entry#A0ABI0NM67-1", "sequence": { "sequence": "MASKEGGMAFSRKSYKLTSDAERSRVTGIVHEKLLSDYLHRVFASPDHRPAAATSRKPLNFQNLPEHLDQLLHVDDKEDEESQEQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWIYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDEGTLSFSLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPLQDPPSTSLVRAQRLLGCFRAVLSMELDPVEGRLVEKESSEWQLQGQPTVLLTLAHIFHHFAPLLCEVYVVEAVLMSFLLGVVEAGPPEQAQTVVHHVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLSLQIHYLRLTIAILSHEKSRKFLLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHRSPREGKEEVREETSEERLRRRAYERGCQRLKKRIEVVEELQVQILKLLLNNKDNNGGEASRYIFLTKFRKFLQENASGRGNTPMLCPPEYMVCFLHRLISALRFYWDEYKASKPRTSFSEEAYVPPQIFYNGKVDYFDLQRLGGLLSHLRKTLKDDLASKANILIDPMELQATTMDDLDEDEEPAPAAAQRPMQALAVGGALPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSASEKVKVRTLSAEQRTREDIEGSQWNEGLLVGRPPEEPEHPLTENSLLEVLDGVVMMYNLSVHQQLGKMVGVSDDVNEYAMALRDTEDKLRRCPKRRKDILAELSKSQKVFSEKLDHLSRRLAWVHAAVYSQEKMQDIYWLLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRLAAILAKHFADTRIVGTDIRDSLMQALASYVCYPNSLRAVERIPEEQRIAMVRNLLAPYEQRPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKPEDASLPSLQKPCPSTLLQQHMADLLREGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVSLLRVLEMTITLVPEIFLDWARPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGLESVDHYPILVAVTGILVRLLVHGPASGTERATSVLLADPCFQLRSISYLLGQPEPPAPGTALPAPDRKHFSLQSCKWAREDRDLGLGQVIRLKNKFPGWKY", "length": 1240, "header": "tr|A0ABI0NM67-1|A0ABI0NM67_BOVIN Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=RNF123 PE=4 SV=1 CANONICAL=E1BL26-1" }, "locus": { "chromosome": "22", "start_pos": 50507304, "end_pos": 50484809, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142217.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142217.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106129.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106129.1" } ] } }, { "isoform_ac": "E1BL26-1", "url": "https://www.uniprot.org/uniprotkb/E1BL26/entry#E1BL26-1", "sequence": { "sequence": "MASKEGGMAFSRKSYKLTSDAERSRVTGIVHEKLLSDYLHRVFASPDHRPAAATSRKPLNFQNLPEHLDQLLHVDDKEDEESQEQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWIYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDEGTLSFSLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPLQDPPSTSLVRAQRLLGCFRAVLSMELDPVEGRLVEKESSEWQLQGQPTVLLTLAHIFHHFAPLLCEVYVVEAVLMSFLLGVVEAGPPEQAQTVVHHVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLSLQIHYLRLTIAILSHEKSRKFLLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHRSPREGKEEVREETSEERLRRRAYERGCQRLKKRIEVVEELQVQILKLLLNNKDNNGGEASRYIFLTKFRKFLQENASGRGNTPMLCPPEYMVCFLHRLISALRFYWDEYKASKPRTSFSEEAYVPPQIFYNGKVDYFDLQRLGGLLSHLRKTLKDDLASKANILIDPMELQATTMDDLDEDEEPAPAAAQRPMQALAVGGALPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSASEKVKVRTLSAEQRTREDIEGSQWNEGLLVGRPPEEPEHPLTENSLLEVLDGVVMMYNLSVHQQLGKMVGVSDDVNEYAMALRDTEDKLRRCPKRRKDILAELSKSQKVFSEKLDHLSRRLAWVHAAVYSQEKMQDIYWLLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRLAAILAKHFADTRIVGTDIRDSLMQALASYVCYPNSLRAVERIPEEQRIAMVRNLLAPYEQRPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKPEDASLPSLQKPCPSTLLQQHMADLLREGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVSLLRVLEMTITLVPEIFLDWARPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGLESVDHYPILVAVTGILVRLLVHGPASGTERATSVLLADPCFQLRSISYLLGQPEPPAPGTALPAPDRKHFSLQSYTDYINVEELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAHPISAVFQPCGHKSCKACIDQHLMNNKDCFFCKATIVSVEDWDKAAHASATSSAA", "length": 1313, "header": "tr|E1BL26-1|E1BL26_BOVIN Isoform 1 of E3 ubiquitin-protein ligase RNF123 OS=Bos taurus OX=9913 GN=RNF123 PE=4 SV=4 CANONICAL=E1BL26-1" }, "locus": { "chromosome": "22", "start_pos": 50507304, "end_pos": 50484255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045376.5", "url": "https://www.ensembl.org/id/ENSBTAT00000045376.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042771.5", "url": "https://www.ensembl.org/id/ENSBTAP00000042771.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:514160", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514160", "resource": "KEGG Pathway" }, { "id": "R-BTA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "E1BL26", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-6781814", "name": "USP19 deubiquitinates RNF123", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MUD4-1", "E1BL26-1" ], "evidence": [ { "id": "R-BTA-6781814", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6781814" } ] }, { "id": "R-BTA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983140" } ] }, { "id": "R-BTA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4I9-1", "E1BJS7-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q1JQA1-1", "Q29RQ5-1", "Q32LN5-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0AAA9RXI4-1", "Q4U5R4-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983147" } ] }, { "id": "R-BTA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983156" } ] }, { "id": "R-BTA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1MAR8", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] } ] }, { "uniprot_ac": "A0A3Q1MLB6", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] } ] }, { "uniprot_ac": "A0A3Q1MLH2", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] } ] }, { "uniprot_ac": "A0A3Q1N3G7", "gene_name": "TRIM36", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] } ] }, { "uniprot_ac": "A0AAA9RXI4", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] } ] }, { "uniprot_ac": "A0AAA9RXX2", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] } ] }, { "uniprot_ac": "A0AAA9RZ14", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] } ] }, { "uniprot_ac": "A0AAA9S100", "gene_name": "MKRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] } ] }, { "uniprot_ac": "A0AAA9TKS8", "gene_name": "RNF217", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] } ] }, { "uniprot_ac": "A0AAA9TWH7", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] } ] }, { "uniprot_ac": "A0AAF6DMH9", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] } ] }, { "uniprot_ac": "A0ABI0NWC8", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] } ] }, { "uniprot_ac": "A0JN74", "gene_name": "TRIM11", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] } ] }, { "uniprot_ac": "A1A4I9", "gene_name": "UFL1", "activity": [ { "ec_number": "2.3.2.-", "activity": "", "evidence": [ { "id": "A1A4I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I9" } ] } ] }, { "uniprot_ac": "A3KN22", "gene_name": "UBE2M", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] } ] }, { "uniprot_ac": "A5D7F8", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] } ] }, { "uniprot_ac": "A5PJC4", "gene_name": "UBE2L6", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] } ] }, { "uniprot_ac": "A5PKG6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] } ] }, { "uniprot_ac": "A6H795", "gene_name": "UBE2W", "activity": [ { "ec_number": "2.3.2.25", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein].", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] } ] }, { "uniprot_ac": "E1B782", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] } ] }, { "uniprot_ac": "E1B7D3", "gene_name": "TRIM39", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] } ] }, { "uniprot_ac": "E1B7G3", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] } ] }, { "uniprot_ac": "E1B7Q7", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] } ] }, { "uniprot_ac": "E1B8R6", "gene_name": "ARIH2", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] } ] }, { "uniprot_ac": "E1BAV2", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] } ] }, { "uniprot_ac": "E1BBN5", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] } ] }, { "uniprot_ac": "E1BBY2", "gene_name": "TRIM41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] } ] }, { "uniprot_ac": "E1BCU1", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] } ] }, { "uniprot_ac": "E1BCW1", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] } ] }, { "uniprot_ac": "E1BH71", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] } ] }, { "uniprot_ac": "E1BID7", "gene_name": "TRIM69", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] } ] }, { "uniprot_ac": "E1BIP5", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] } ] }, { "uniprot_ac": "E1BIW0", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] } ] }, { "uniprot_ac": "E1BJS7", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] } ] }, { "uniprot_ac": "E1BL26", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] } ] }, { "uniprot_ac": "E1BNQ6", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] } ] }, { "uniprot_ac": "E1BNY9", "gene_name": "HUWE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] } ] }, { "uniprot_ac": "F1MBM6", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] } ] }, { "uniprot_ac": "F1MEX6", "gene_name": "RNF19B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] } ] }, { "uniprot_ac": "F1MJ10", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] } ] }, { "uniprot_ac": "F1MJS5", "gene_name": "HECTD3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] } ] }, { "uniprot_ac": "F1MLS5", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] } ] }, { "uniprot_ac": "F1MM41", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] } ] }, { "uniprot_ac": "F1MTS8", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] } ] }, { "uniprot_ac": "F1MUD4", "gene_name": "USP19", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "F1MUD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUD4" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "F1MUD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUD4" } ] } ] }, { "uniprot_ac": "F1MWS4", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] } ] }, { "uniprot_ac": "F1MYL0", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] } ] }, { "uniprot_ac": "F1N1X8", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] } ] }, { "uniprot_ac": "F1N3I3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] } ] }, { "uniprot_ac": "F1N495", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] } ] }, { "uniprot_ac": "F1N5G3", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] } ] }, { "uniprot_ac": "F1N645", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] } ] }, { "uniprot_ac": "F1N6G5", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] } ] }, { "uniprot_ac": "F1N703", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] } ] }, { "uniprot_ac": "F1N7A0", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] } ] }, { "uniprot_ac": "P61085", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] } ] }, { "uniprot_ac": "Q0II22", "gene_name": "RNF126", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] } ] }, { "uniprot_ac": "Q0P5K3", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] } ] }, { "uniprot_ac": "Q17QG5", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] } ] }, { "uniprot_ac": "Q1JQA1", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] } ] }, { "uniprot_ac": "Q1RML1", "gene_name": "UBE2S", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] } ] }, { "uniprot_ac": "Q1RMW1", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] } ] }, { "uniprot_ac": "Q1RMX2", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] } ] }, { "uniprot_ac": "Q29RQ5", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] } ] }, { "uniprot_ac": "Q2T9X7", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] } ] }, { "uniprot_ac": "Q2TA03", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] } ] }, { "uniprot_ac": "Q2TA10", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] } ] }, { "uniprot_ac": "Q32L27", "gene_name": "UBE2Q2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] } ] }, { "uniprot_ac": "Q32LN1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] } ] }, { "uniprot_ac": "Q32LN5", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] } ] }, { "uniprot_ac": "Q32P99", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] } ] }, { "uniprot_ac": "Q32PA5", "gene_name": "UBE2C", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] } ] }, { "uniprot_ac": "Q3MHP1", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] } ] }, { "uniprot_ac": "Q4U5R4", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] } ] }, { "uniprot_ac": "Q5E9J6", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] } ] }, { "uniprot_ac": "Q7YRV4", "gene_name": "TRIM21", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 255, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 1253, "end_pos": 1291, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJ75-1", "uniprot_ac": "E1BJ75", "uniprot_id": "E1BJ75_BOVIN", "mass": { "chemical_mass": 46846.0, "monoisotopic_mass": 46846.0 }, "refseq": { "ac": "NP_001192974", "name": "cartilage-associated protein precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192974" }, "gene_names": [ { "name": "CRTAP", "type": "recommended", "evidence": [ { "id": "E1BJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ75" } ] }, { "name": "CRTAP", "type": "synonym", "evidence": [ { "id": "NP_001192974", "database": "RefSeq", "url": 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"database": "UniProtKB", "id": "E1BJ75", "url": "https://www.uniprot.org/uniprotkb/E1BJ75" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CRTAP", "url": "https://www.uniprot.org/uniprotkb/E1BJ75", "locus": { "chromosome": "22", "start_pos": 7492376, "end_pos": 7458981, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021442", "url": "https://www.ensembl.org/id/ENSBTAG00000021442" } ] } } ], "crossref": [ { "id": "E1BJ75", "url": "https://alphafold.ebi.ac.uk/entry/E1BJ75", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021442", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021442", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540924", "url": "https://www.ncbi.nlm.nih.gov/gene/540924", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540924", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540924", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WPETVEY", "url": "https://omabrowser.org/oma/group/WPETVEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJ75", "url": "https://www.orthodb.org/?gene=E1BJ75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13986", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13986", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13986:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13986:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192974", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192974", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TUI7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUI7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ75", "url": "https://www.uniprot.org/uniprotkb/E1BJ75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ75-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGRRAAAALLALLCAVCALHSGRAQYERYSFRSFPRDELMPLESAYRHALDQYSSEHWAESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPTAGLARYPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPKAIAAAHTFLLKHPDDEMMKRNMAYYKSLPDAEDYIKDLETKSYESLFIRAVRAYNGENWRTCITDMELALPDFFKAFYECLAACEGSREIRDFKDFYLSIADHYVEVLECKIQCEENLTPVIGGYPVEKFVATMYHYLQFAYYKLNDLKNAAPCAVSYLLFDQSDKVMQQNLVYYQYHRDKWALADEHFQPRPEAVQFFNVTMLQKELYDFAKENLMDDDEGEVLEYVDDLLELEETS", "length": 401, "header": "tr|E1BJ75-1|E1BJ75_BOVIN Isoform 1 of Cartilage-associated protein OS=Bos taurus OX=9913 GN=CRTAP PE=3 SV=1 CANONICAL=E1BJ75-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TUI7-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ75/entry#A0AAA9TUI7-1", "sequence": { "sequence": "MEPGRRAAAALLALLCAVCALHSGRAQYERYSFRSFPRDELMPLESAYRHALDQYSSEHWAESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPTAGLARYPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPKAIAAAHTFLLKHPDDEMMKRNMAYYKSLPDAEDYIKDLETKSYESLFIRAVRAYNGENWRTCITDMELALPDFFKAFYECLAACEGSREIRDFKDFYLSIAVNDLKNAAPCAVSYLLFDQSDKVMQQNLVYYQYHRDKWALADEHFQPRPEAVQFFNVTMLQKELYDFAKENLMDDDEGEVLEYVDDLLELEETS", "length": 358, "header": "tr|A0AAA9TUI7-1|E1BJ75_BOVIN Computationally mapped isoform of Cartilage-associated protein OS=Bos taurus OX=9913 GN=CRTAP PE=3 SV=1 CANONICAL=E1BJ75-1" }, "locus": { "chromosome": "22", "start_pos": 7491536, "end_pos": 7459268, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110747.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110747.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102032.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102032.1" } ] } }, { "isoform_ac": "E1BJ75-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ75/entry#E1BJ75-1", "sequence": { "sequence": "MEPGRRAAAALLALLCAVCALHSGRAQYERYSFRSFPRDELMPLESAYRHALDQYSSEHWAESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPTAGLARYPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPKAIAAAHTFLLKHPDDEMMKRNMAYYKSLPDAEDYIKDLETKSYESLFIRAVRAYNGENWRTCITDMELALPDFFKAFYECLAACEGSREIRDFKDFYLSIADHYVEVLECKIQCEENLTPVIGGYPVEKFVATMYHYLQFAYYKLNDLKNAAPCAVSYLLFDQSDKVMQQNLVYYQYHRDKWALADEHFQPRPEAVQFFNVTMLQKELYDFAKENLMDDDEGEVLEYVDDLLELEETS", "length": 401, "header": "tr|E1BJ75-1|E1BJ75_BOVIN Isoform 1 of Cartilage-associated protein OS=Bos taurus OX=9913 GN=CRTAP PE=3 SV=1 CANONICAL=E1BJ75-1" }, "locus": { "chromosome": "22", "start_pos": 7491536, "end_pos": 7459268, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028588.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028588.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028588.4", "url": "https://www.ensembl.org/id/ENSBTAP00000028588.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 97, "start_aa": "Thr", "end_pos": 97, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr97", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540924", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540924", "resource": "KEGG Pathway" }, { "id": "R-BTA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MK61-1", "protein_name": "Cartilage associated protein", "gene_name": "Crtap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPRSPAAALLVLLCAGCVLSPGRAQYERYSFRSFPRDELMPLESAYRHALDQYSGEHWAESVGYLEVSLRLHRLLRDSEAFCHRNCSAATPAPAPSGPASPASHRELRLFGGVLRRAQCLKRCKQGLPAFRQSQPSRAVLADFQQREPYKFLQFAYFKANDLPKAIAAAHTYLLKHPEDEMMKRNMEYYKSLPGAEDHIKDLETKSYESLFVRAVRAYNGENWRTSISDMELALPDFFKAFYECLAACEGSREIKDFKDFYLSIADHYVEVLECKIHCEETLTPVIGGYPVEKFVATIYHYLQFAYYKLNDLKNAAPCAVSYLLFDPNDKVMQQNLVYYQYHRDKWGLSDEHFQPRLEAVQFFNVTTLQKELYDFAQEHLMDDDEGEVVEYVDDLLEMEESA", "length": 403 }, "evidence": [ { "id": "E1BJ75", "url": "https://omabrowser.org/oma/group/E1BJ75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75718-1", "protein_name": "Cartilage-associated protein", "gene_name": "CRTAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPGRRGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHWAESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPAAGLASYPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPKAIAAAHTFLLKHPDDEMMKRNMAYYKSLPGAEDYIKDLETKSYESLFIRAVRAYNGENWRTSITDMELALPDFFKAFYECLAACEGSREIKDFKDFYLSIADHYVEVLECKIQCEENLTPVIGGYPVEKFVATMYHYLQFAYYKLNDLKNAAPCAVSYLLFDQNDKVMQQNLVYYQYHRDTWGLSDEHFQPRPEAVQFFNVTTLQKELYDFAKENIMDDDEGEVVEYVDDLLELEETS", "length": 401 }, "evidence": [ { "id": "E1BJ75", "url": "https://omabrowser.org/oma/group/E1BJ75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CYD3-1", "protein_name": "Cartilage-associated protein", "gene_name": "Crtap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPRSPTAALLVLLCVGCAPTPGRGQYERYSFRSFPRDELMPLESAYRHALDQYSGEHWAESVGYLEVSLRLHRLLRDSEAFCHRNCSAATPAPAPAGPASHAELRLFGSVLRRAQCLKRCKQGLPAFRQSQPSRSVLADFQQREPYKFLQFAYFKANDLPKAIAAAHTYLLKHPDDEMMKRNMEYYKSLPGAEDHIKDLETKSYESLFVRAVRAYNGENWRTSISDMELALPDFLKAFYECLAACEGSREIKDFKDFYLSIADHYVEVLECKIRCEETLTPVIGGYPVEKFVATMYHYLQFAYYKLNDLKNAAPCAVSYLLFDQSDRVMQQNLVYYQYHRDKWGLSDEHFQPRPEAVQFFNVTTLQKELYDFAQEHLMDDDEGEVVEYVDDLLETEESA", "length": 400 }, "evidence": [ { "id": "E1BJ75", "url": "https://omabrowser.org/oma/group/E1BJ75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of post-translational protein modification", "id": "GO:1901874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901874", "evidence": [ { "database": "UniProtKB", "id": "E1BJ75", "url": "https://www.uniprot.org/uniprotkb/E1BJ75" } ], "pmid": "" }, { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "E1BJ75", "url": "https://www.uniprot.org/uniprotkb/E1BJ75" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "E1BJ75", "url": "https://www.uniprot.org/uniprotkb/E1BJ75" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "E1BJ75", "url": "https://www.uniprot.org/uniprotkb/E1BJ75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BJ75", "url": "https://www.uniprot.org/uniprotkb/E1BJ75" } ], "pmid": "" }, { "name": "endoplasmic reticulum", 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"type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJ75-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJ75" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ75" }, { "id": "PF23557", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23557" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Leprecan-like alpha-helical", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 342, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 97 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 280, "end_pos": 282 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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}, { "id": "E1BGH5", "url": "https://www.uniprot.org/uniprotkb/E1BGH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGH5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MPKCTERSYQPQNKLHSRTISHTGVEAKLKRKASPTLFGNDINSVLLTTQSQTRNRVRFKITDPNNRRYEVPHQFVKEFSGTAASDPLYNVEVIHDPFSIKISRRSNSKILFDTSIGPLVYSDQYLQISARLPNEYIYGLGEHIHKRFRHDLYWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFIQPTPIVTYRVIGGILDFYIFLGDTPEQVVQQYQELIGRPAMPAYWNLGFQLSRWNYKTLDVVKAVVQRNRDAGIPFDTQITDIDYMEDKKIFTYDQVTFNGLPEFVQDLHAHGQKYVIILDPAVSIEKRANGAAYESYDRGTAQKVWVNESDGTTAIIGEVWPGLTVYPDFTNPSCIEWWANECYLFHQQVNYDGLWIDMNEVSSFVQGSKKGCSANNLNYPPFTPDILDKLMYSKTICMDAMQYWGKQYDVHSLYGYSMSIATEKAIEKVLPNKRSFILTRSTFAGSGSHSAHWLGDNTASWEQMEWSITGMLEFGLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPYARNHNADGYEHQDPAFFGKDSLLVKSSKHYLNIRYALLPFLYTLFYKAHMFGETVARPFLHEFYEDTNSWIEDTQFLWGPSLLITPVLRQGAETVSAYIPDATWYDFETGVKKPWRKQRVDMQLPADKIGLHLRGGYIIPFQQPAVTTTASRKNPLGLIIALNDNNTAKGDFFWDDGETKDTIQKGNYILYTFSVSNNKLDITCMHSSYPEGTALAFETIKVLGLINTVTEVSVIEDNQPLRAHYNFSYDASNQILLIHNLTFNLGGNFTVQWDQTFLEVEKFTCYPDSNTATKELCEERGCLWQTVHLGSKAPECYFPKEDNSYLVHSTQYSSVGITADLQLNTANRIKLPSDSISSLRVEVKYHKDDMLQFKIYDAQNKRYEVPVPLNIPNTPTSTYETRLYDVEIKENPFGIQIRRRSTRRVIWDSRLPGFAFNNQFIQISTRLPSEYVYGFGEMEHTTFKRDLNWHTWGMFTRDQPPGYKLNSYGFHPYYMALEDENNAHGVLLLNSNAMDVTFQPMPALTYRMIGGILDFYMFLGPSPEVTTKQYHEVIGQPVMPPYWALGFQLCRYGYRNTSQVEEVYNDMVAAQIPYDVQYTDIDYMERQLDFTIDDEFHDLPQFVDKIRSEGMRYIIILDPAISGNETKPYPAFERGQEKDVFVKWPNTSDICWAKVRPDLPNVTIDQSLTEDEAANATKAHAAFPDFFRNSTAEWWAREIIDFYNNQMKFDGLWIDMNEPSSFVNGTTTNQCRNAELNYPPYFPELTKRTDGLHFRTVCMETEQILSDGSSVLHYDVHNLYGWSQLKPTYDALQKATGKRGIIISRSTYPSAGRWSGHWLGDNYATWDNLEKSIIGMMEFSLFGMSYTGADICGFFNNSEYQLCARWMQLGAFYPYARNHNSAFTRRQDPASWNKTFSAMSRDILNIRYTLLPYFYTQMYEIHAHGGTVIRPLLHEFLNEKPTWDIFKQFLWGPAFMVTPVLEPYVDTVEGYVPNARWFDYHTGKDIGVRETFHTFAAPLYEINLHVRGGYILPCQEPANNTFYSRQNYMKLIVAADDNQMAQGSLFWDDGETIDTYERDLYSLVQFNLNKTILTSTILKNGYINRNEMRLGYIHIWGKEKMRVSEVTLTHNGNKESVNFTEDPNLEILDIDLTGNNVTLDEPIEINWS", "length": 1725, "header": "tr|A0AAA9TVW7-1|E1BGH5_BOVIN Computationally mapped isoform of Sucrase-isomaltase OS=Bos taurus OX=9913 GN=SI PE=3 SV=1 CANONICAL=E1BGH5-1" }, "locus": { "chromosome": "1", "start_pos": 102388040, "end_pos": 102273643, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095947.2", "url": "https://www.ensembl.org/id/ENSBTAT00000095947.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101310.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101310.1" } ] } }, { "isoform_ac": "E1BGH5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGH5/entry#E1BGH5-1", "sequence": { "sequence": "MAKQKFSGLEITLIVLFAIVTIIAIALIVVLATKTPAVEEISDSTRGTCPSVLNDPINHRINCIPERSPTQTLCAARGCCWRPWNDSVIPWCFFVNNHGYNAEKVTSTNAGVEAKLKRKASPTLFGNDINSVLLTTQSQTRNRVRFKITDPNNRRYEVPHQFVKEFSGTAASDPLYNVEVIHDPFSIKISRRSNSKILFDTSIGPLVYSDQYLQISARLPNEYIYGLGEHIHKRFRHDLYWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFIQPTPIVTYRVIGGILDFYIFLGDTPEQVVQQYQELIGRPAMPAYWNLGFQLSRWNYKTLDVVKAVVQRNRDAGIPFDTQITDIDYMEDKKIFTYDQVTFNGLPEFVQDLHAHGQKYVIILDPAVSIEKRANGAAYESYDRGTAQKVWVNESDGTTAIIGEVWPGLTVYPDFTNPSCIEWWANECYLFHQQVNYDGLWIDMNEVSSFVQGSKKGCSANNLNYPPFTPDILDKLMYSKTICMDAMQYWGKQYDVHSLYGYSMSIATEKAIEKVLPNKRSFILTRSTFAGSGSHSAHWLGDNTASWEQMEWSITGMLEFGLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPYARNHNADGYEHQDPAFFGKDSLLVKSSKHYLNIRYALLPFLYTLFYKAHMFGETVARPFLHEFYEDTNSWIEDTQFLWGPSLLITPVLRQGAETVSAYIPDATWYDFETGVKKPWRKQRVDMQLPADKIGLHLRGGYIIPFQQPAVTTTASRKNPLGLIIALNDNNTAKGDFFWDDGETKDTIQKGNYILYTFSVSNNKLDITCMHSSYPEGTALAFETIKVLGLINTVTEVSVIEDNQPLRAHYNFSYDASNQILLIHNLTFNLGGNFTVQWDQTFLEVEKFTCYPDSNTATKELCEERGCLWQTVHLGSKAPECYFPKEDNSYLVHSTQYSSVGITADLQLNTANRIKLPSDSISSLRVEVKYHKDDMLQFKIYDAQNKRYEVPVPLNIPNTPTSTYETRLYDVEIKENPFGIQIRRRSTRRVIWDSRLPGFAFNNQFIQISTRLPSEYVYGFGEMEHTTFKRDLNWHTWGMFTRDQPPGYKLNSYGFHPYYMALEDENNAHGVLLLNSNAMDVTFQPMPALTYRMIGGILDFYMFLGPSPEVTTKQYHEVIGQPVMPPYWALGFQLCRYGYRNTSQVEEVYNDMVAAQIPYDVQYTDIDYMERQLDFTIDDEFHDLPQFVDKIRSEGMRYIIILDPAISGNETKPYPAFERGQEKDVFVKWPNTSDICWAKVRPDLPNVTIDQSLTEDEAANATKAHAAFPDFFRNSTAEWWAREIIDFYNNQMKFDGLWIDMNEPSSFVNGTTTNQCRNAELNYPPYFPELTKRTDGLHFRTVCMETEQILSDGSSVLHYDVHNLYGWSQLKPTYDALQKATGKRGIIISRSTYPSAGRWSGHWLGDNYATWDNLEKSIIGMMEFSLFGMSYTGADICGFFNNSEYQLCARWMQLGAFYPYARNHNSAFTRRQDPASWNKTFSAMSRDILNIRYTLLPYFYTQMYEIHAHGGTVIRPLLHEFLNEKPTWDIFKQFLWGPAFMVTPVLEPYVDTVEGYVPNARWFDYHTGKDIGVRETFHTFAAPLYEINLHVRGGYILPCQEPANNTFYSRQNYMKLIVAADDNQMAQGSLFWDDGETIDTYERDLYSLVQFNLNKTILTSTILKNGYINRNEMRLGYIHIWGKEKMRVSEVTLTHNGNKESVNFTEDPNLEILDIDLTGNNVTLDEPIEINWS", "length": 1812, "header": "tr|E1BGH5-1|E1BGH5_BOVIN Isoform 1 of Sucrase-isomaltase OS=Bos taurus OX=9913 GN=SI PE=3 SV=3 CANONICAL=E1BGH5-1" }, "locus": { "chromosome": "1", "start_pos": 102388040, "end_pos": 102272282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023366.8", "url": "https://www.ensembl.org/id/ENSBTAT00000023366.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023366.6", "url": "https://www.ensembl.org/id/ENSBTAP00000023366.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 295, "start_aa": "Thr", "end_pos": 295, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr295", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:504366", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504366", "resource": "KEGG Pathway" }, { "id": "R-BTA-189085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189085", "resource": "Reactome", "description": "Digestion of dietary carbohydrate" } ], "orthologs": [ { "uniprot_canonical_ac": "P14410-1", "protein_name": "Sucrase-isomaltase, intestinal", "gene_name": "SI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPATTRVTTNPSDSGKCPNVLNDPVNVRINCIPEQFPTEGICAQRGCCWRPWNDSLIPWCFFVDNHGYNVQDMTTTSIGVEAKLNRIPSPTLFGNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVKEFTGPTVSDTLYDVKVAQNPFSIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYGIGEQVHKRFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFIQPTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQYDGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIPDAIWYDYESGAKRPWRKQRVDMYLPADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLIADLKLNLGRNFSVQWNQIFSENERFNCYPDADLATEQKCTQRGCVWRTGSSLSKAPECYFPRQDNSYSVNSARYSSMGITADLQLNTANARIKLPSDPISTLRVEVKYHKNDMLQFKIYDPQKKRYEVPVPLNIPTTPISTYEDRLYDVEIKENPFGIQIRRRSSGRVIWDSWLPGFAFNDQFIQISTRLPSEYIYGFGEVEHTAFKRDLNWNTWGMFTRDQPPGYKLNSYGFHPYYMALEEEGNAHGVFLLNSNAMDVTFQPTPALTYRTVGGILDFYMFLGPTPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTDIDYMERQLDFTIGEAFQDLPQFVDKIRGEGMRYIIILDPAISGNETKTYPAFERGQQNDVFVKWPNTNDICWAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWAREIVDFYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSVLHYDVHNLYGWSQMKPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDKSIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPASWNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVPNARWFDYHTGKDIGVRGQFQTFNASYDTINLHVRGGHILPCQEPAQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDGESIDTYERDLYLSVQFNLNQTTLTSTILKRGYINKSETRLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNEDTTNMILRIDLTTHNVTLEEPIEINWS", "length": 1827 }, "evidence": [ { "id": "E1BGH5", "url": "https://omabrowser.org/oma/group/E1BGH5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P23739-1", "protein_name": "Sucrase-isomaltase, intestinal", "gene_name": "Si", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKKKFSALEISLIVLFIIVTAIAIALVTVLATKVPAVEEIKSPTPTSNSTPTSTPTSTSTPTSTSTPSPGKCPPEQGEPINERINCIPEQHPTKAICEERGCCWRPWNNTVIPWCFFADNHGYNAESITNENAGLKATLNRIPSPTLFGEDIKSVILTTQTQTGNRFRFKITDPNNKRYEVPHQFVKEETGIPAADTLYDVQVSENPFSIKVIRKSNNKVLCDTSVGPLLYSNQYLQISTRLPSEYIYGFGGHIHKRFRHDLYWKTWPIFTRDEIPGDNNHNLYGHQTFFMGIGDTSGKSYGVFLMNSNAMEVFIQPTPIITYRVTGGILDFYIFLGDTPEQVVQQYQEVHWRPAMPAYWNLGFQLSRWNYGSLDTVSEVVRRNREAGIPYDAQVTDIDYMEDHKEFTYDRVKFNGLPEFAQDLHNHGKYIIILDPAISINKRANGAEYQTYVRGNEKNVWVNESDGTTPLIGEVWPGLTVYPDFTNPQTIEWWANECNLFHQQVEYDGLWIDMNEVSSFIQGSLNLKGVLLIVLNYPPFTPGILDKVMYSKTLCMDAVQHWGKQYDVHSLYGYSMAIATEQAVERVFPNKRSFILTRSTFGGSGRHANHWLGDNTASWEQMEWSITGMLEFGIFGMPLVGATSCGFLADTTEELCRRWMQLGAFYPFSRNHNAEGYMEQDPAYFGQDSSRHYLTIRYTLLPFLYTLFYRAHMFGETVARPFLYEFYDDTNSWIEDTQFLWGPALLITPVLRPGVENVSAYIPNATWYDYETGIKRPWRKERINMYLPGDKIGLHLRGGYIIPTQEPDVTTTASRKNPLGLIVALDDNQAAKGELFWDDGESKDSIEKKMYILYTFSVSNNELVLNCTHSSYAEGTSLAFKTIKVLGLREDVRSITVGENDQQMATHTNFTFDSANKILSITALNFNLAGSFIVRWCRTFSDNEKFTCYPDVGTATEGTCTQRGCLWQPVSGLSNVPPYYFPPENNPYTLTSIQPLPTGITAELQLNPPNARIKLPSNPISTLRVGVKYHPNDMLQFKIYDAQHKRYEVPVPLNIPDTPTSSNERLYDVEIKENPFGIQVRRRSSGKLIWDSRLPGFGFNDQFIQISTRLPSNYLYGFGEVEHTAFKRDLNWHTWGMFTRDQPPGYKLNSYGFHPYYMALENEGNAHGVLLLNSNGMDVTFQPTPALTYRTIGGILDFYMFLGPTPEIATRQYHEVIGFPVMPPYWALGFQLCRYGYRNTSEIEQLYNDMVAANIPYDVQYTDINYMERQLDFTIGERFKTLPEFVDRIRKDGMKYIVILAPAISGNETQPYPAFERGIQKDVFVKWPNTNDICWPKVWPDLPNVTIDETITEDEAVNASRAHVAFPDFFRNSTLEWWAREIYDFYNEKMKFDGLWIDMNEPSSFGIQMGGKVLNECRRMMTLNYPPVFSPELRVKEGEGASISEAMCMETEHILIDGSSVLQYDVHNLYGWSQVKPTLDALQNTTGLRGIVISRSTYPTTGRWGGHWLGDNYTTWDNLEKSLIGMLELNLFGIPYIGADICGVFHDSGYPSLYFVGIQVGAFYPYPRESPTINFTRSQDPVSWMKLLLQMSKKVLEIRYTLLPYFYTQMHEAHAHGGTVIRPLMHEFFDDKETWEIYKQFLWGPAFMVTPVVEPFRTSVTGYVPKARWFDYHTGADIKLKGILHTFSAPFDTINLHVRGGYILPCQEPARNTHLSRQNYMKLIVAADDNQMAQGTLFGDDGESIDTYERGQYTSIQFNLNQTTLTSTVLANGYKNKQEMRLGSIHIWGKGTLRISNANLVYGGRKHQPPFTQEEAKETLIFDLKNMNVTLDEPIQITWS", "length": 1841 }, "evidence": [ { "id": "E1BGH5", "url": "https://omabrowser.org/oma/group/E1BGH5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BGH5", "url": "https://www.uniprot.org/uniprotkb/E1BGH5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BGH5", "url": "https://www.uniprot.org/uniprotkb/E1BGH5" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "E1BGH5", "url": "https://www.uniprot.org/uniprotkb/E1BGH5" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "E1BGH5", "url": "https://www.uniprot.org/uniprotkb/E1BGH5" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "E1BGH5", "url": "https://www.uniprot.org/uniprotkb/E1BGH5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "E1BGH5", "url": "https://www.uniprot.org/uniprotkb/E1BGH5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "E1BGH5", "url": "https://www.uniprot.org/uniprotkb/E1BGH5" } ], "pmid": "" }, { "name": "alpha-glucosidase activity", "id": "GO:0090599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090599", "evidence": [ { "database": "UniProtKB", "id": "E1BGH5", "url": "https://www.uniprot.org/uniprotkb/E1BGH5" } ], "pmid": "" }, { "name": "alpha-1,4-glucosidase activity", "id": "GO:0004558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004558", "evidence": [ { "database": "UniProtKB", "id": "E1BGH5", "url": "https://www.uniprot.org/uniprotkb/E1BGH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1220, "end_pos": 1222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1288, "end_pos": 1290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1310, "end_pos": 1312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1325, "end_pos": 1327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1339, "end_pos": 1341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1353, "end_pos": 1355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1388, "end_pos": 1390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1520, "end_pos": 1522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1557, "end_pos": 1559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1683, "end_pos": 1685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1733, "end_pos": 1735, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1782, "end_pos": 1784, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1800, "end_pos": 1802, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1810, "end_pos": 1812, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 809, "end_pos": 811, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" }, { "start_pos": 890, "end_pos": 892, "annotation": "n_glycosylation_sequon" }, { "start_pos": 904, "end_pos": 906, "annotation": "n_glycosylation_sequon" }, { "start_pos": 912, "end_pos": 914, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH5" }, { "id": "PS51448", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51448" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "P-type", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 96, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 295 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1220, "end_pos": 1222 }, { "start_pos": 1288, "end_pos": 1290 }, { "start_pos": 1310, "end_pos": 1312 }, { "start_pos": 1325, "end_pos": 1327 }, { "start_pos": 1339, "end_pos": 1341 }, { "start_pos": 1353, "end_pos": 1355 }, { "start_pos": 1388, "end_pos": 1390 }, { "start_pos": 1520, "end_pos": 1522 }, { "start_pos": 1557, "end_pos": 1559 }, { "start_pos": 1683, "end_pos": 1685 }, { "start_pos": 1733, "end_pos": 1735 }, { "start_pos": 1782, "end_pos": 1784 }, { "start_pos": 1800, "end_pos": 1802 }, { "start_pos": 1810, "end_pos": 1812 }, { "start_pos": 441, "end_pos": 443 }, { "start_pos": 809, "end_pos": 811 }, { "start_pos": 85, "end_pos": 87 }, { "start_pos": 890, "end_pos": 892 }, { "start_pos": 904, "end_pos": 906 }, { "start_pos": 912, "end_pos": 914 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 3314 }, { "field": "total_sites", "count": 1614 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 1591 }, { "field": "total_sites", "count": 1097 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1723 }, { "field": "total_sites", "count": 1180 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 64 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1BEN8-1", "uniprot_ac": "E1BEN8", "uniprot_id": "E1BEN8_BOVIN", "mass": { "chemical_mass": 86819.0, "monoisotopic_mass": 86819.0 }, "refseq": { "ac": "NP_001178407", "name": "transcription initiation factor TFIID subunit 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178407" }, "gene_names": [ { "name": "TAF5", "type": "recommended", "evidence": [ { "id": "E1BEN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ] }, { "name": "TAF5", "type": "synonym", "evidence": [ { "id": "NP_001178407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178407" } ] } ], "protein_names": [ { "name": "Transcription initiation factor TFIID subunit 5", "type": "recommended", "evidence": [ { "id": "E1BEN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEN8/entry#names_and_taxonomy" } ] }, { "name": "TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa", "type": "synonym", "evidence": [ { "id": "NP_001178407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178407" } ] }, { "name": "Transcription initiation factor TFIID 100 kDa subunit", "type": "synonym", "evidence": [ { "id": "E1BEN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEN8/entry#names_and_taxonomy" } ] }, { "name": "transcription initiation factor TFIID subunit 5", "type": "synonym", "evidence": [ { "id": "NP_001178407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178407" } ] } ], "function": [ { "annotation": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF5 is involved in two modules of TFIID, in TFIID-A together with TAF3 and TBP, and in TFIID-B with TAF8. Involved in contacts between TFIID and TFIIF in the PIC.", "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8#function" }, { "database": "UniProtKB", "id": "ARBA00058398", "url": "https://www.uniprot.org/uniprotkb/ARBA00058398#function" }, { "database": "UniProtKB", "id": "A0AAA9TXF9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXF9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TAF5", "url": "https://www.uniprot.org/uniprotkb/E1BEN8", "locus": { "chromosome": "26", "start_pos": 23982420, "end_pos": 23967689, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009709", "url": "https://www.ensembl.org/id/ENSBTAG00000009709" } ] } } ], "crossref": [ { "id": "E1BEN8", "url": "https://alphafold.ebi.ac.uk/entry/E1BEN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009709", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009709", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "516001", "url": "https://www.ncbi.nlm.nih.gov/gene/516001", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516001", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516001", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HNHPVWD", "url": "https://omabrowser.org/oma/group/HNHPVWD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEN8", "url": "https://www.orthodb.org/?gene=E1BEN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19879", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19879", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19879:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19879:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04494", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6804756", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73776", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73776", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73779", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73779", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-75953", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75953", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-76042", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178407", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TXF9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXF9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEN8-1", "url": "https://www.uniprot.org/uniprotkb/E1BEN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGGGGTTNSGPNGGGGNVAAASSAGGDGGTPKPSVAVSAVAPAGAAPVPAAAPEASAPHDRQTLLAVLQFLRQSNLREAEEALRREARLLEEAVAGSGAPGEADSAGAETASALLSRVTASAPGPSAPDPPVSGASGSAAVSGLATGSVAPGKVGSVSVEDQPDVSAVLSAYSQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLAGEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQAADLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAVKAFEDVETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ", "length": 800, "header": "tr|E1BEN8-1|E1BEN8_BOVIN Isoform 1 of Transcription initiation factor TFIID subunit 5 OS=Bos taurus OX=9913 GN=TAF5 PE=3 SV=2 CANONICAL=E1BEN8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TXF9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEN8/entry#A0AAA9TXF9-1", "sequence": { "sequence": "MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGGGGTTNSGPNGGGGNVAAASSAGGDGGTPKPSVAVSAVAPAGAAPVPAAAPEASAPHDRQTLLAVLQFLRQSNLREAEEALRREARLLEEAVAGSGAPGEADSAGAETASALLSRVTASAPGPSAPDPPVSGASGSAAVSGLATGSVAPGKVGSVSVEDQPDVSAVLSAYSQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLAGEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQAADLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAVKAFEDVETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ", "length": 745, "header": "tr|A0AAA9TXF9-1|E1BEN8_BOVIN Computationally mapped isoform of Transcription initiation factor TFIID subunit 5 OS=Bos taurus OX=9913 GN=TAF5 PE=3 SV=1 CANONICAL=E1BEN8-1" }, "locus": { "chromosome": "26", "start_pos": 23981585, "end_pos": 23967701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087954.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087954.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103339.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103339.1" } ] } }, { "isoform_ac": "E1BEN8-1", "url": "https://www.uniprot.org/uniprotkb/E1BEN8/entry#E1BEN8-1", "sequence": { "sequence": "MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGGGGTTNSGPNGGGGNVAAASSAGGDGGTPKPSVAVSAVAPAGAAPVPAAAPEASAPHDRQTLLAVLQFLRQSNLREAEEALRREARLLEEAVAGSGAPGEADSAGAETASALLSRVTASAPGPSAPDPPVSGASGSAAVSGLATGSVAPGKVGSVSVEDQPDVSAVLSAYSQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLAGEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQAADLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAVKAFEDVETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ", "length": 800, "header": "tr|E1BEN8-1|E1BEN8_BOVIN Isoform 1 of Transcription initiation factor TFIID subunit 5 OS=Bos taurus OX=9913 GN=TAF5 PE=3 SV=2 CANONICAL=E1BEN8-1" }, "locus": { "chromosome": "26", "start_pos": 23981585, "end_pos": 23967701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012808.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012808.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012808.4", "url": "https://www.ensembl.org/id/ENSBTAP00000012808.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:516001", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516001", "resource": "KEGG Pathway" }, { "id": "R-BTA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-BTA-6804756", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "resource": "Reactome", "description": "Regulation of TP53 Activity through Phosphorylation" }, { "id": "R-BTA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" }, { "id": "R-BTA-73776", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73776", "resource": "Reactome", "description": "RNA Polymerase II Promoter Escape" }, { "id": "R-BTA-73779", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73779", "resource": "Reactome", "description": "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" }, { "id": "R-BTA-75953", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75953", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation" }, { "id": "R-BTA-76042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76042", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation And Promoter Clearance" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZH66-1", "protein_name": "Transcription initiation factor TFIID subunit 5", "gene_name": "Taf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALAEEQTEVAVKLESEGPPTLLPPQAGDGAGEGSGGTPNNGPNGGGGNVAAAAGGDGGTPKPVVAVSAAAPAGAAPVPAAPAEAGAPHDRQTLLAVLQFLRQSNLREAEEALRREARLLEEAVAGSGAPGELDGAGAEAASALLSRVTASVPGSAAPDTPGAGASVTSVFSGSASGPAAPGKVASVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHESEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLAGEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ", "length": 798 }, "evidence": [ { "id": "E1BEN8", "url": "https://omabrowser.org/oma/group/E1BEN8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S845-1", "protein_name": "Transcription initiation factor TFIID subunit 5", "gene_name": "TAF5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGGGGATNNGPNGGGGNVAASSSAGGDGGTPKPSVAVSAVAPAGVAPVAAAAPEAGGPHDRQTLLAVLQFLRQNNLREAEEALRREARLLEEAVAGSGAPGEADGAGAETASALLSRVTSSGPGPAAPEPPGSAASGASAVSGLATGPAAPGKVGSLAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLAGEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDNIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQAADLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAVKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ", "length": 800 }, "evidence": [ { "id": "E1BEN8", "url": "https://omabrowser.org/oma/group/E1BEN8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P38129-1", "protein_name": "SAGA complex/transcription factor TFIID complex subunit TAF5", "gene_name": "TAF5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSQKQSTNQNQNGTHQPQPVKNQRTNNAAGANSGQQPQQQSQGQSQQQGRSNGPFSASDLNRIVLEYLNKKGYHRTEAMLRAESGRTLTPQNKQSPANTKTGKFPEQSSIPPNPGKTAKPISNPTNLSSKRDAEGGIVSSGRLEGLNAPENYIRAYSMLKNWVDSSLEIYKPELSYIMYPIFIYLFLNLVAKNPVYARRFFDRFSPDFKDFHGSEINRLFSVNSIDHIKENEVASAFQSHKYRITMSKTTLNLLLYFLNENESIGGSLIISVINQHLDPNIVESVTAREKLADGIKVLSDSENGNGKQNLEMNSVPVKLGPFPKDEEFVKEIETELKIKDDQEKQLNQQTAGDNYSGANNRTLLQEYKAMNNEKFKDNTGDDDKDKIKDKIAKDEEKKESELKVDGEKKDSNLSSPARDILPLPPKTALDLKLEIQKVKESRDAIKLDNLQLALPSVCMYTFQNTNKDMSCLDFSDDCRIAAAGFQDSYIKIWSLDGSSLNNPNIALNNNDKDEDPTCKTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDLKKATTEPSAEPDEPFIGYLGDVTASINQDIKEYGRRRTVIPTSDLVASFYTKKTPVFKVKFSRSNLALAGGAFRP", "length": 798 }, "evidence": [ { "id": "E1BEN8", "url": "https://omabrowser.org/oma/group/E1BEN8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q15542-1", "protein_name": "Transcription initiation factor TFIID subunit 5", "gene_name": "TAF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTTNNGPNGGGGNVAASSSTGGDGGTPKPTVAVSAAAPAGAAPVPAAAPDAGAPHDRQTLLAVLQFLRQSKLREAEEALRREAGLLEEAVAGSGAPGEVDSAGAEVTSALLSRVTASAPGPAAPDPPGTGASGATVVSGSASGPAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLAGEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ", "length": 800 }, "evidence": [ { "id": "E1BEN8", "url": "https://omabrowser.org/oma/group/E1BEN8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54KH7-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSTPPQQPNQSQPTQSPPIITTPQTTTTTISSPIAQTTIPASGVGSSSANAVTSTPSPTTTTSTAPSTPTPTPTPTPNPNTTSSISTSTPTPTTTTTTILTPPLPQNTTTPITAVPSSASAIPITATTTISPNTSSNITALPTTPTTPNITPTTTAATTTTTTTPTTSSSSSTTNAPTSNEVKSAQTKDKYDLAVLNYLRKKGYTNAEAILKQEIFNSSQSMSSPISPSDDEATNTTTTNQTNINTVTDNLGSSDDQELAQYLHMYNSSNKGDTSNPQNYLEQYKKLGNWIHSSLDIYKNELLSILYPVFVHSYIDLITKGYPQQARELMEKIGPDHEEYFGDDLKLLRGISNTDHLKENELVDLFRNNRWNIKMCAYSFELLMSFLHQSNFILLLGLINQYIHINVSNLRPGFIDDEQYSISFQSEKDAGDLNSTPINYHAFKPEFEDDVLVQQKEKQQLEQGRILPLTDPNAPLPPVVAPPPPPPPTSGYIPKLKKKDKKKKEVKDERMSKIESNVPIPNLTERFENELMEDFTKCVSLSSSHLPSICFYTIFNTYQGLNTTDISKDAQLVAGGFSDSSVKIWNLKEMKEQRLQQQQQQQQQQQQQQNSNQNGYFENGNFASSASSASSAMNGSGNNNENNKSTTANNNLNSGSSSSSNKLQKQQKESEFKTFLGHSGPVYGCSFSPDSQYLLSCSEDTTARLWSMETMSNLVCYKGHNFPVWDVSFSPFGFYFATASHDRTARLWTTNHISPLRIFTGHLSDCNTVRFHPNINYLATGSNDKSARLWEIQTGKCVRIFMGHRAPIYTVAFSPDGRLLATAGEDTSVILWDLSTGKKVKKMDGHTKCVYSLDFSCDGSILASGSSDCTVRLWDVKKAFNSSLSTQPSSLINDESRKRKTLKSKLFSDELLETYPTKQTPVYNVCFSRRNLLLASGAFNTLTAFDKF", "length": 948 }, "evidence": [ { "id": "E1BEN8", "url": "https://omabrowser.org/oma/group/E1BEN8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6S7B0-1", "protein_name": "Transcription initiation factor TFIID subunit 5", "gene_name": "TAF5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDPEQINEFVVGYLKKKGFSSAAKDLESYHHQNNNGSSFTSVDYHNDPELTKLIRSFSQQEDDPTRYREGYSKLRSWAYNSLDLYKHELLRVMYPVFIHCYMDLVGKGHTQEARAFFNSFRKDHEMVHLRDLQKLEGVLSPSHLEEMEFARSLRKSKVNIKFCQYSYELLLQYLHSTVSTLMLGIINEHINFQVYSGQPTSSSDDIEAVTIVGSFQDTANHINQKEIQWGLLEDSLEDRLEKTGGLLSDSEKGQGESKDGDADDSKKRSTEIGKQGSSLKKLKKDKAGNATAKVARLETITVSPAPRVKPELALPVMSTDVEQSILEDLRNRVQLSSVAMPSVSFYTFVNTHNGLNCSSISHDGSLVAGGFSDSSIKVWDMAKIGQAGSGALQAENDSSDQSIGPNGRRSYTLLLGHSGPVYSATFSPPGDFVLSSSADTTIRLWSTKLNANLVCYKGHNYPVWDAQFSPFGHYFASCSHDRTARIWSMDRIQPLRIMAGHLSDVDCVQWHPNCNYIATGSSDKTVRLWDVQTGECVRIFIGHRSMVLSLAMSPDGRYMASGDEDGTIMMWDLSTARCITPLMGHNSCVWSLSYSGEGSLLASGSADCTVKLWDVTSSTKLTKAEEKNGNSNRLRSLRTFPTKSTPVHALRFSRRNLLFAAGAISKPAN", "length": 669 }, "evidence": [ { "id": "E1BEN8", "url": "https://omabrowser.org/oma/group/E1BEN8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8C092-1", "protein_name": "Transcription initiation factor TFIID subunit 5", "gene_name": "Taf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTPNNGPNGGGGGNVAVAAAAGGDGGTPKPGVAVSAAAPAGAAPVPAAPAEAGAPHDRQTLLAVLQFLRQSNLREAEEALRREARLLEEAVAGSGAPGELDGAGAEAASALLSRVTASVPGSAAPEPPGTGASVTSVFSGSASGPAAPGKVASVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRIYRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLAGEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRYHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAVKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ", "length": 801 }, "evidence": [ { "id": "E1BEN8", "url": "https://omabrowser.org/oma/group/E1BEN8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ], "pmid": "" }, { "name": "transcription factor TFTC complex", "id": "GO:0033276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033276", "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ], "pmid": "" }, { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ], "pmid": "" }, { "name": "mRNA transcription by RNA polymerase II", "id": "GO:0042789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042789", "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "E1BEN8", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEN8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 800, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEN8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEN8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEN8" }, { "id": "PF04494", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04494" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TFIID subunit TAF5 NTD2", "eco_id": "ECO_0000259", "start_pos": 209, "end_pos": 337, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 294, "end_pos": 296 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 631, "end_pos": 633 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEZ5-1", "uniprot_ac": "E1BEZ5", "uniprot_id": "E1BEZ5_BOVIN", "mass": { "chemical_mass": 56139.0, "monoisotopic_mass": 56139.0 }, "refseq": {}, "gene_names": [ { "name": "NUFIP1", "type": "recommended", "evidence": [ { "id": "E1BEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ] } ], "protein_names": [ { "name": "Nuclear FMR1 interacting protein 1", "type": "synonym", "evidence": [ { "id": "E1BEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NUFIP1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5", "locus": { "chromosome": "12", "start_pos": 15118007, "end_pos": 15157140, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009415", "url": "https://www.ensembl.org/id/ENSBTAG00000009415" } ] } } ], "crossref": [ { "id": "E1BEZ5", "url": "https://alphafold.ebi.ac.uk/entry/E1BEZ5", "database": "AlphaFoldDB", 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"MGEPAGGAVPPAAWFPAPELTPTLGPLRDRASRPNNWMLWAMPPPPPSSLPAAGSEPALEAQPHEEARTFPGAPPPFDAHILPGAQPPFDAQSPLDSQPQPNGQPSWNFQASASRYWTQSPGGFPWHQQPHSTPVKHTYFPRKHDARVNDFSVSPRRKQKKKKRKEPVFHYFCDTCDRGFKNQEKYDTHMSEHTECPEVDCSFSAHEKIVQFHWRNAFSPQMHAPGMKKIKLDTPEEIARWREERRKNYPTLANIERKKKLKLEKEKRGAVLTTTQYGKMKGMTRHSQMAKIQSPGKHHKWKNGHAEQRTAAGSGHHLGDLKPESPLEANSDPLGVLVNTDSESDKEEKPQSAVIPKEVTPALCSLMSSYGGLSGSESEPEEAPIRTEADILAEDQVLHSNTPKKPSQDVKATVKNSSEAKCESQKRSFKNTNPKRKKNDLNYRTLFEPRTHHPYLLEMLLAPDIRHERNVILQCVRYIIKKDFFGLNTTTVNTKDE", "length": 497, "header": "tr|E1BEZ5-1|E1BEZ5_BOVIN Isoform 1 of Nuclear FMR1 interacting protein 1 OS=Bos taurus OX=9913 GN=NUFIP1 PE=4 SV=3 CANONICAL=E1BEZ5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TYH9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5/entry#A0AAA9TYH9-1", "sequence": { "sequence": "MGEPAGGAVPPAAWFPAPELTPTLGPLRDRASRPNNWMLWAMPPPPPSSLPAAGSEPALEAQPHEEARTFPGAPPPFDAHILPGAQPPFDAQSPLDSQPQPNGQPSWNFQASASRYWTQSPGGFPWHQQPHSTPVKHTYFPRKHDARVNDFSVSPRRKQKKKKRKEPVFHYFCDTCDRGFKNQEKYDTHMSEHTECPEVDCSFSAHEKIVQFHWRNMHAPGMKKIKLDTPEEIARWREERRKNYPTLANIERKKKLKLEKEKRGAVLTTTQYGKMKGMTRHSQMAKIQSPGKHHKWKNGHAEQRTAAGSGHHLGDLKPESPLEANSDPLGVLVNTDSEAPIRTEADILAEDQVLHSNTPKKPSQDVKATVKNSSEAKCESQKRSFKNTNPKRKKNDLNYRTLFEPRTHHPYLLEMLLAPDIRHERNVILQCVRYIIKKDFFGLNTTTVNTKDE", "length": 453, "header": "tr|A0AAA9TYH9-1|E1BEZ5_BOVIN Computationally mapped isoform of Nuclear FMR1 interacting protein 1 OS=Bos taurus OX=9913 GN=NUFIP1 PE=4 SV=1 CANONICAL=E1BEZ5-1" }, "locus": { "chromosome": "12", "start_pos": 15157108, "end_pos": 15118251, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125168.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125168.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102288.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102288.1" } ] } }, { "isoform_ac": "E1BEZ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5/entry#E1BEZ5-1", "sequence": { "sequence": "MGEPAGGAVPPAAWFPAPELTPTLGPLRDRASRPNNWMLWAMPPPPPSSLPAAGSEPALEAQPHEEARTFPGAPPPFDAHILPGAQPPFDAQSPLDSQPQPNGQPSWNFQASASRYWTQSPGGFPWHQQPHSTPVKHTYFPRKHDARVNDFSVSPRRKQKKKKRKEPVFHYFCDTCDRGFKNQEKYDTHMSEHTECPEVDCSFSAHEKIVQFHWRNAFSPQMHAPGMKKIKLDTPEEIARWREERRKNYPTLANIERKKKLKLEKEKRGAVLTTTQYGKMKGMTRHSQMAKIQSPGKHHKWKNGHAEQRTAAGSGHHLGDLKPESPLEANSDPLGVLVNTDSESDKEEKPQSAVIPKEVTPALCSLMSSYGGLSGSESEPEEAPIRTEADILAEDQVLHSNTPKKPSQDVKATVKNSSEAKCESQKRSFKNTNPKRKKNDLNYRTLFEPRTHHPYLLEMLLAPDIRHERNVILQCVRYIIKKDFFGLNTTTVNTKDE", "length": 497, "header": "tr|E1BEZ5-1|E1BEZ5_BOVIN Isoform 1 of Nuclear FMR1 interacting protein 1 OS=Bos taurus OX=9913 GN=NUFIP1 PE=4 SV=3 CANONICAL=E1BEZ5-1" }, "locus": { "chromosome": "12", "start_pos": 15157108, "end_pos": 15118251, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012392.7", "url": "https://www.ensembl.org/id/ENSBTAT00000012392.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012392.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012392.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "perichromatin fibrils", "id": "GO:0005726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005726", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "pre-snoRNP complex", "id": "GO:0070761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070761", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" }, { "name": "box C/D snoRNP assembly", "id": "GO:0000492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000492", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ5", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEZ5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 497, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEZ5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEZ5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ5" }, { "id": "PS50157", "database": "PROSITE", "url": 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK51-1", "uniprot_ac": "E1BK51", "uniprot_id": "E1BK51_BOVIN", "mass": { "chemical_mass": 54312.0, "monoisotopic_mass": 54312.0 }, "refseq": { "ac": "NP_001192764", "name": "E3 ubiquitin-protein ligase TRIM62", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192764" }, "gene_names": [ { "name": "TRIM62", "type": "recommended", "evidence": [ { "id": "E1BK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ] }, { "name": "TRIM62", "type": "synonym", "evidence": [ { "id": "NP_001192764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192764" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase TRIM62", "type": "recommended", "evidence": [ { "id": "E1BK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK51/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "E1BK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK51/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase TRIM62", "type": "synonym", "evidence": [ { "id": "NP_001192764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192764" } ] }, { "name": "Tripartite motif-containing protein 62", "type": "synonym", "evidence": [ { "id": "E1BK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK51/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C-type lectin receptors; leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways. E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51#function" }, { "database": "UniProtKB", "id": "ARBA00059305", "url": "https://www.uniprot.org/uniprotkb/ARBA00059305#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TRIM62", "url": "https://www.uniprot.org/uniprotkb/E1BK51", "locus": { "chromosome": "2", "start_pos": 120551871, "end_pos": 120514845, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020671", "url": "https://www.ensembl.org/id/ENSBTAG00000020671" } ] } } ], "crossref": [ { "id": "E1BK51", "url": "https://alphafold.ebi.ac.uk/entry/E1BK51", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020671", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020671", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13744", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13744", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16608", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16608", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19792", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19792", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "516886", "url": "https://www.ncbi.nlm.nih.gov/gene/516886", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035830", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035830", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516886", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516886", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TEHWNRQ", "url": "https://omabrowser.org/oma/group/TEHWNRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BK51", "url": "https://www.orthodb.org/?gene=E1BK51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192764", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9U0X5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0X5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK51-1", "url": "https://www.uniprot.org/uniprotkb/E1BK51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSAFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFEELQRELKEQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGMASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475, "header": "tr|E1BK51-1|E1BK51_BOVIN Isoform 1 of E3 ubiquitin-protein ligase TRIM62 OS=Bos taurus OX=9913 GN=TRIM62 PE=3 SV=1 CANONICAL=E1BK51-1" }, "isoforms": [ { "isoform_ac": "A0AAA9U0X5-1", "url": "https://www.uniprot.org/uniprotkb/E1BK51/entry#A0AAA9U0X5-1", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSAFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFEELQSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGMASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 443, "header": "tr|A0AAA9U0X5-1|E1BK51_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM62 OS=Bos taurus OX=9913 GN=TRIM62 PE=3 SV=1 CANONICAL=E1BK51-1" }, "locus": { "chromosome": "2", "start_pos": 120550867, "end_pos": 120515593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101570.2", "url": "https://www.ensembl.org/id/ENSBTAT00000101570.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103637.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103637.1" } ] } }, { "isoform_ac": "E1BK51-1", "url": "https://www.uniprot.org/uniprotkb/E1BK51/entry#E1BK51-1", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSAFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFEELQRELKEQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGMASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475, "header": "tr|E1BK51-1|E1BK51_BOVIN Isoform 1 of E3 ubiquitin-protein ligase TRIM62 OS=Bos taurus OX=9913 GN=TRIM62 PE=3 SV=1 CANONICAL=E1BK51-1" }, "locus": { "chromosome": "2", "start_pos": 120550867, "end_pos": 120515593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027551.5", "url": "https://www.ensembl.org/id/ENSBTAT00000027551.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027551.2", "url": "https://www.ensembl.org/id/ENSBTAP00000027551.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:516886", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516886", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZA67-1", "protein_name": "Tripartite motif containing 62", "gene_name": "ERMAP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSFGCEHYFCRRCITEHWVRQEPQGARDCPECRRTFTEPTLAPSLKLANIVERYSAFPLDAILGAQRSPFPCKDHEKVKLFCLTDRTVVCFFCDEPAVHEQHQVTNVDDAFEELQRELKEQLQGLQESERGHTEALHLLKRQLADTKSSAKSLRATIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKIQRYSQQLRKVQEGSQILQERLAEADKHAFLAGVASLSERLKGKIHETNLTYEDFPTSKYMGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPRRFDVEVSVLGTQAFGGGVHYWEVVVSEKTQWMIGLAHEAVTRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVKSKLEKVGVFLDYDKGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475 }, "evidence": [ { "id": "E1BK51", "url": "https://omabrowser.org/oma/group/E1BK51/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SV81-1", "protein_name": "E3 ubiquitin-protein ligase TRIM62", "gene_name": "TRIM62", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSAFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFEELQRELKEQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475 }, "evidence": [ { "id": "E1BK51", "url": "https://omabrowser.org/oma/group/E1BK51/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R947-1", "protein_name": "E3 ubiquitin-protein ligase TRIM62", "gene_name": "Trim62", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSAFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFEELQRELKEQLQALQDSAREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSERLKGKTHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475 }, "evidence": [ { "id": "E1BK51", "url": "https://omabrowser.org/oma/group/E1BK51/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80V85-1", "protein_name": "E3 ubiquitin-protein ligase TRIM62", "gene_name": "Trim62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSAFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFEELQRELKEQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTMDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475 }, "evidence": [ { "id": "E1BK51", "url": "https://omabrowser.org/oma/group/E1BK51/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BVG3-1", "protein_name": "E3 ubiquitin-protein ligase TRIM62", "gene_name": "TRIM62", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSSFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475 }, "evidence": [ { "id": "E1BK51", "url": "https://omabrowser.org/oma/group/E1BK51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "regulation of viral entry into host cell", "id": "GO:0046596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046596", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" }, { "name": "negative regulation of viral transcription", "id": "GO:0032897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032897", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" }, { "name": "protein K27-linked ubiquitination", "id": "GO:0044314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044314", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" }, { "name": "viral release from host cell", "id": "GO:0019076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019076", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" }, { "name": "positive regulation of antifungal innate immune response", "id": "GO:1905036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905036", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BK51", "url": "https://www.uniprot.org/uniprotkb/E1BK51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BK51-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 475, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BK51-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BK51" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK51" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 128, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK51" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 277, "end_pos": 475, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK51" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 54, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 263, "end_pos": 265 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"E1BJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX5" } ] }, { "name": "MTBP", "type": "synonym", "evidence": [ { "id": "NP_001180106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180106" } ] } ], "protein_names": [ { "name": "MDM2 binding protein", "type": "synonym", "evidence": [ { "id": "E1BJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX5/entry#names_and_taxonomy" } ] }, { "name": "Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa", "type": "synonym", "evidence": [ { "id": "NP_001180106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180106" } ] }, { "name": "mdm2-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001180106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180106" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJX5", "url": "https://www.uniprot.org/uniprotkb/E1BJX5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MTBP", "url": "https://www.uniprot.org/uniprotkb/E1BJX5", "locus": { "chromosome": "14", "start_pos": 81863369, "end_pos": 81786835, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006770", "url": "https://www.ensembl.org/id/ENSBTAG00000006770" } ] } } ], "crossref": [ { "id": "E1BJX5", "url": "https://alphafold.ebi.ac.uk/entry/E1BJX5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006770", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006770", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617904", "url": "https://www.ncbi.nlm.nih.gov/gene/617904", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617904", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617904", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HFYGEQI", "url": "https://omabrowser.org/oma/group/HFYGEQI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJX5", "url": "https://www.orthodb.org/?gene=E1BJX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14382", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14382", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14382:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14382:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14918", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14918", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9766229", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9766229", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001180106", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180106", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9U1M3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1M3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJX5", "url": "https://www.uniprot.org/uniprotkb/E1BJX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJX5-1", "url": "https://www.uniprot.org/uniprotkb/E1BJX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRYLLLAVWGEGKAAAAAGSGRGPEASRVEGPGRPPDLRAANVYHLLKRSITASLSPEDSTFPACSVGGIPGSRKWFFAVQAICGFYQFCSSHWEEIHFGAEKDDIEDVLQTNTEECLSAVECFEEEDSNSRESLSLADLYEESAEGLHQLSDKLPAPGRAMIDIILLPSDKDPPKLRDCLPTVGALKHLKEWYSAKITIAGDHCEINYQKIAEYLSANTVSFEDLRNAIDSKELWRGKIQIWERKFGSEISFPEFCLKGVTPKNFSTSNLKTCFLDKKIIPSKDKDILPKVFHYYGPALEFVQMIKLSDLPSCYMSDIEFELGLTKNSTKQTSRLLLEQISSLCGEAGALFVLPCTIGSILTPPPSQLSSRRWKEYMARKPRTITVPDVEVKGESSSYYLLLQGNGNGKCKATLIHSANQINGSFALSLIHGKMKATTEETKLSFPLDLSSLPSFSREQLIQREKQLAGVQALAVKECLKRRKLAKQREVISVDELKSLLTCTRERFLGHFDAVLPKTSLIKTDKTSSMLHDNSSLELTSSRLVETNPLEWPERHVLQNLETCEKAKQKMRTGSLPRSSEQLLGHKEGPRDSVTLLDAKELLKFFTSDGLPIGDLQPLQIQKGEKTFVLTPELSPQKLRGLPFEKASVCHYHGIEYCLDDRKALERDGGFSELQSRLIRYETQSTCARGSSPGPTVLSPLPSPAVLSEPLSVPDGEALQRELRTDVSRVKRRSKDVNCLYPPKRLVRSGSSDSLLSQTSGSGHHHHAVPSRKLRAERPLPVTCRSALSSETPGATAKAGSGPKAVRESETSRPAKESRSQKHTRILKEVVAETLKKHGITEAHGCFSACSQRLFEISKFYLKDLKTSRGLFEEMKKTTNNNVVQVIEWVLEKARKK", "length": 898, "header": "tr|E1BJX5-1|E1BJX5_BOVIN Isoform 1 of MDM2 binding protein OS=Bos taurus OX=9913 GN=MTBP PE=4 SV=2 CANONICAL=E1BJX5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9U1M3-1", "url": "https://www.uniprot.org/uniprotkb/E1BJX5/entry#A0AAA9U1M3-1", "sequence": { "sequence": "MDRYLLLAVWGEGKAAAAAGSGRGPEASRVEGPGRPPDLRAANVYHLLKRSITASLSPEDSTFPACSVGGIPGSRKWFFAVQAICGFYQFCSSHWEEIHFGAEKDDIEDVLQTNTEECLSAVECFEEEDSNSRESLSLADLYEESAEGLHQLSDKLPAPGRAMIDIILLPSDKDPPKLRDCLPTVGALKHLKEWYSAKITIAGDHCEINYQKIAEYLSANTVSFEDLRNAIDSKELWRGKIQIWERKFGSEISFPEFCLKGVTPKNFSTSNLKTCFLDKKIIPSKDKDILPKAGALFVLPCTIGSILTPPPSQLSSRRWKEYMARKPRTITVPDVEVKGESSSYYLLLQGNGNGKCKATLIHSANQINGSFALSLIHGKMKATTEETKLSFPLDLSSLPSFSREQLIQREKQLAGVQALAVKECLKRRKLAKQREVISVDELKSLLTCTRERFLGHFDAVLPKTSLIKTDKTSSMLHDNSSLELTSSRLVETNPLEWPERHVLQNLETCEKAKQKMRTGSLPRSSEQLLGHKEGPRDSVTLLDAKELLKFFTSDGLPIGDLQPLQIQKGEKTFVLTPELSPQKLRGLPFEKASVCHYHGIEYCLDDRKALERDGGFSELQSRLIRYETQSTCARGSSPGPTVLSPLPSPAVLSEPLSVPDGEALQRELRTDVSRVKRRSKDVNCLYPPKRLVRSGSSDSLLSQTSGSGHHHHAVPSRKLRAERPLPVTCRSALSSETPGATAKAGSGPKAVRESETSRPAKESRSQKHTRILKEVVAETLKKHGITEAHGCFSACSQRLFEISKFYLKDLKTSRGLFEEMKKTTNNNVVQVIEWVLEKARKK", "length": 842, "header": "tr|A0AAA9U1M3-1|E1BJX5_BOVIN Computationally mapped isoform of MDM2 binding protein OS=Bos taurus OX=9913 GN=MTBP PE=4 SV=1 CANONICAL=E1BJX5-1" }, "locus": { "chromosome": "14", "start_pos": 81863065, "end_pos": 81787034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102967.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102967.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103725.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103725.1" } ] } }, { "isoform_ac": "E1BJX5-1", "url": "https://www.uniprot.org/uniprotkb/E1BJX5/entry#E1BJX5-1", "sequence": { "sequence": "MDRYLLLAVWGEGKAAAAAGSGRGPEASRVEGPGRPPDLRAANVYHLLKRSITASLSPEDSTFPACSVGGIPGSRKWFFAVQAICGFYQFCSSHWEEIHFGAEKDDIEDVLQTNTEECLSAVECFEEEDSNSRESLSLADLYEESAEGLHQLSDKLPAPGRAMIDIILLPSDKDPPKLRDCLPTVGALKHLKEWYSAKITIAGDHCEINYQKIAEYLSANTVSFEDLRNAIDSKELWRGKIQIWERKFGSEISFPEFCLKGVTPKNFSTSNLKTCFLDKKIIPSKDKDILPKVFHYYGPALEFVQMIKLSDLPSCYMSDIEFELGLTKNSTKQTSRLLLEQISSLCGEAGALFVLPCTIGSILTPPPSQLSSRRWKEYMARKPRTITVPDVEVKGESSSYYLLLQGNGNGKCKATLIHSANQINGSFALSLIHGKMKATTEETKLSFPLDLSSLPSFSREQLIQREKQLAGVQALAVKECLKRRKLAKQREVISVDELKSLLTCTRERFLGHFDAVLPKTSLIKTDKTSSMLHDNSSLELTSSRLVETNPLEWPERHVLQNLETCEKAKQKMRTGSLPRSSEQLLGHKEGPRDSVTLLDAKELLKFFTSDGLPIGDLQPLQIQKGEKTFVLTPELSPQKLRGLPFEKASVCHYHGIEYCLDDRKALERDGGFSELQSRLIRYETQSTCARGSSPGPTVLSPLPSPAVLSEPLSVPDGEALQRELRTDVSRVKRRSKDVNCLYPPKRLVRSGSSDSLLSQTSGSGHHHHAVPSRKLRAERPLPVTCRSALSSETPGATAKAGSGPKAVRESETSRPAKESRSQKHTRILKEVVAETLKKHGITEAHGCFSACSQRLFEISKFYLKDLKTSRGLFEEMKKTTNNNVVQVIEWVLEKARKK", "length": 898, "header": "tr|E1BJX5-1|E1BJX5_BOVIN Isoform 1 of MDM2 binding protein OS=Bos taurus OX=9913 GN=MTBP PE=4 SV=2 CANONICAL=E1BJX5-1" }, "locus": { "chromosome": "14", "start_pos": 81863065, "end_pos": 81787034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008906.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008906.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008906.4", "url": "https://www.ensembl.org/id/ENSBTAP00000008906.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 697, "start_aa": "Thr", "end_pos": 697, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr697", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:617904", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617904", "resource": "KEGG Pathway" }, { "id": "R-BTA-9766229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9766229", "resource": "Reactome", "description": "Degradation of CDH1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y8Y0-1", "protein_name": "MDM2 binding protein", "gene_name": "Mtbp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRYLLLVSWREGKFRSVAGGEMEPGTEASSLESTEKQPHLTATNIYHLLKRSINDSIHPDDSTFPACSVGGTPHSRKWFFAAQAICGFYQFCSSDWQEIHFDAEKDKIEDVLQANVEECQSAVECFEEDDSNSRESLSLADLYEESAENLHQLSDKLPAPGRAMIDVILLPSDKDPPKLKECLPIVGALKHLKEWHSAKVIVAGSHCETNCQKIAEYLSATVVPLEEFGNAIDSRELWRGEIQMRERKFGFEVNFPEFCLKGVTPTNVSAYNLNTCFLAKKIASSKDKNILPKVFHYYGSALEFVQMIKLSDLPSCYVSDIEFELEVTGHCTRQNSMLLLEQISSLCGKVGALFLLPCTISNVLLPPPNQLASRKWKEYIAKKPKTISVPDVDVKGEFSGYHLLLQGSGRRKCRATLLHSASQINGSVALTLIHGKMKARTEAAQPSFPFDFSSLPRFSEEQVLQREKQLASVQVLALKECLKRRKAANQPEAVSTDELKSLLALTRERFLDRFDVLTPKAVLTQTDTMKAAGMVNDASRVESYSSSSMETNPLEWPERHVLQNLETSEKAKQKMRTGSLPHSAEQLLGHKEGPRDSITLLDAKELLKYFTSEGLPVGDLQPLQIQRGEKPFVLTPELSPGKLQILPFEKASECHYHGIETGFVGIHCHPQPFALCAGLRYCLDDQKALERDGGFSELQSRLIRYETQTTCTRDSFPVPTVWSPLPSPAVLSEPQSVPEGDALQGELRTEVSGLKRRSKDASCLYPQKRITKSESSDCLLSQASCNSNHYHHVGTSRKPQAERCVSVLPLPGREASKVTVKTSSGQKRAHESKSSKQIKESRSQKHTRMLKEVVTETLKRHHITEAHESFDACSQRLFDISKFYLKDLKTSRGLFEEMKKTANNNVVQVIEWVVEKMSKR", "length": 921 }, "evidence": [ { "id": "E1BJX5", "url": "https://omabrowser.org/oma/group/E1BJX5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YAU3-1", "protein_name": "MDM2 binding protein", "gene_name": "MTBP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERYVLLLGWGAAAGGAEHGAGTEAGIAAGGEAGEGICGHSAVTVANIYKLLKEKCNSSIKADTMTFPACSVAGVPGIKKWYFASHVICGYYQFCSSDWEEINSDMQKNEDSLQTTIEKCLGNIQNFEEDDNNSRESLSMADVYDEAAESLHQLADRLPAPGRAMVDIILQAVEGDAPKLKDCLPVIGALKHLREWHSAQITIATSDSKGWQKIADYLSADFVSSDNVLDVINLKELWRGKVQIWERKFASEVSFPEFCMKSTSAKPLSTSHVNSCFAVKEEQRCVNSDALPEVFHYYGPALEFLRMVVLSELPPFFISDLEFELSLARKGRKEMSALLLDQISSLSGKVGALVSLTCNVSSIAIPSPAQLSTKKWKEYMARKPKVITVPEIDLKGESCRYYFLLQGNGSGGCKATLIHSATQINGMATLAAVNRMLKTNAGETESNFPIDDFIESLPRFCGKQIVQREKKLSHLQASALKEYLKRKKLTEQPPVISTGELKSLLELTRECFLDLWRTNLPESVLQKAANKTSSHTVASESDLMEPNPLEWPERHVLQNLENFEKIKQKMRASMLAHSSEQLLGHKDSQRESLTSLDAKELLKYFTPEGLPVGDLQPLHIPKRESAFFLTPELTPRKLRGLPFEKAAGCYYHGIEYCLDNRKALERDLGYAELQARLIRYETQTTCTKECCPLPVVLSPLPAVLSPLPSPAVLSEPGSVPDGESLQSEFRTEVLRLKRRSKDLDCFCPRKRLMKSESTDSLLSQASGGNGSHNAVVVTRKRSERSVSLTSMVLKQSGQPHKAATRSGSASCVSATESETSKPVKESRSQKHTRMLKEVVAKTLQKHGIAEDHKCFASCSQRLFEISKFYLKDLKTSRGLLDEMKKTASNNAKQVIEWVLEKTGK", "length": 904 }, "evidence": [ { "id": "E1BJX5", "url": "https://omabrowser.org/oma/group/E1BJX5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8BJS8-1", "protein_name": "Mdm2-binding protein", "gene_name": "Mtbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRYLLLVTWREGKFRSVAGGEIEPGTEATSLESTDKQPDLTATNIYHLLKRSISDSIHPDDSTFPACSVGGTPHSRKWFFAVQAICGFYQFCSSDWQEIHFDAEKDKIEDVLQANIEECQSAVECFEEDDSNSRESLPLADLYEESAENLHQLSDKLPAPGRAMIDIILLPSDKDPPKLKECLPIVGALKHLKEWHSAKVIIAGSYCEINCQKIAEYLSASVVPLEEFRNAIDPRELWRGEIQMRERKFGFEISFPEFCLKGVTPTNVSAYNLNTCFLAKKIASSKVFHYYGPALEFVQMIKLSDLPSCYMSDIEFELEVTGHCTRQNSMLLLEQISSLCGKVGALFVLPCTVSNVLIPPPSQLASRKWKEYMAKKPKTISVPDVAVKGEFSGYHLLLQGMGKRKCRATLLHSASQINGSFALSVIHGKMKTKAGEARPSFPFDFSSLPRFSEEQVLQREKQLASFQVLALKECLKRRKAANQPEAFSADELKSLLALTRERFLGHFDVLPTEAALAQTDTVKAAGVVNDDGTVEPYSSSLMETNPLEWPERHVLQNLETSEKAKQKMRTGSLPRSSEQLLGHKEGPRDSLTLLDAKELLKYFTSDGLPVGDLQPLHIQRGEKPFVLTPELSPGKLQVLPFEKASECHYHGIEYCLDDQKALERDGGFSELQSRLIRYETQTTCTRDSFPVPTVLSPLPSPAVLSEPQSVPEGEALQGELRTEVSGLKRRSKDPSCLYPQKRLTRSESSDCLPSQASCNSNHHHHTGKPRKPQAERCVSGLPLPGREASKDTSKTSSGQKRAHESKSSKQMKESRSQKHTRMLKEVVKDTLKRHHITEAHESFTACSQRLFDISKFYLKDLKTSRGLFEEMKKTANNNVVQVIEWVVEKMSKK", "length": 894 }, "evidence": [ { "id": "E1BJX5", "url": "https://omabrowser.org/oma/group/E1BJX5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96DY7-1", "protein_name": "Mdm2-binding protein", "gene_name": "MTBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRYLLLVIWGEGKFPSAASREAEHGPEVSSGEGTENQPDFTAANVYHLLKRSISASINPEDSTFPACSVGGIPGSKKWFFAVQAIYGFYQFCSSDWQEIHFDTEKDKIEDVLQTNIEECLGAVECFEEEDSNSRESLSLADLYEEAAENLHQLSDKLPAPGRAMVDIILLLSDKDPPKLKDYLPTVGALKHLREWYSAKITIAGNHCEINCQKIAEYLSANVVSLEDLRNVIDSKELWRGKIQIWERKFGFEISFPEFCLKGVTLKNFSTSNLNTDFLAKKIIPSKDKNILPKVFHYYGPALEFVQMIKLSDLPSCYMSDIEFELGLTNSTKQNSVLLLEQISSLCSKVGALFVLPCTISNILIPPPNQLSSRKWKEYIAKKPKTISVPDVEVKGECSSYYLLLQGNGNRRCKATLIHSANQINGSFALNLIHGKMKTKTEEAKLSFPFDLLSLPHFSGEQIVQREKQLANVQVLALEECLKRRKLAKQPETVSVAELKSLLVLTRKHFLDYFDAVIPKMILRKMDKIKTFNILNDFSPVEPNSSSLMETNPLEWPERHVLQNLETFEKTKQKMRTGSLPHSSEQLLGHKEGPRDSITLLDAKELLKYFTSDGLPIGDLQPLPIQKGEKTFVLTPELSPGKLQVLPFEKASVCHYHGIEYCLDDRKALERDGGFSELQSRLIRYETQTTCTRESFPVPTVLSPLPSPVVSSDPGSVPDGEVLQNELRTEVSRLKRRSKDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTETLKKHSITETHECFTACSQRLFEISKFYLKDLKTSRGLFEEMKKTANNNAVQVIDWVLEKTSKK", "length": 904 }, "evidence": [ { "id": "E1BJX5", "url": "https://omabrowser.org/oma/group/E1BJX5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of protein ubiquitination", "id": "GO:0031396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031396", "evidence": [ { "database": "UniProtKB", "id": "E1BJX5", "url": "https://www.uniprot.org/uniprotkb/E1BJX5" } ], "pmid": "" }, { "name": "traversing start control point of mitotic cell cycle", "id": "GO:0007089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007089", "evidence": [ { "database": "UniProtKB", "id": "E1BJX5", "url": "https://www.uniprot.org/uniprotkb/E1BJX5" } ], "pmid": "" }, { "name": "protein localization to kinetochore", "id": "GO:0034501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034501", "evidence": [ { "database": "UniProtKB", "id": "E1BJX5", "url": "https://www.uniprot.org/uniprotkb/E1BJX5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "E1BJX5", "url": "https://www.uniprot.org/uniprotkb/E1BJX5" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BJX5", "url": "https://www.uniprot.org/uniprotkb/E1BJX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJX5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 898, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJX5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJX5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX5" }, { "id": "PF14918", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14918" }, { "id": "PF14919", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14919" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DM2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 267, "start_aa": "Met", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX5" }, { "id": "PF14920", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14920" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MDN2-binding protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 633, "end_pos": 888, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 697 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 535, "end_pos": 537 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG61-1", "uniprot_ac": "E1BG61", "uniprot_id": "E1BG61_BOVIN", "mass": { "chemical_mass": 41539.0, "monoisotopic_mass": 41539.0 }, "refseq": {}, "gene_names": [ { "name": "FRRS1L", "type": "recommended", "evidence": [ { "id": "E1BG61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG61" } ] } ], "protein_names": [ { "name": "Ferric chelate reductase 1 like", "type": "synonym", "evidence": [ { "id": "E1BG61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG61/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG61", "url": "https://www.uniprot.org/uniprotkb/E1BG61" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FRRS1L", "url": "https://www.uniprot.org/uniprotkb/E1BG61", "locus": { "chromosome": "8", "start_pos": 98694929, "end_pos": 98723259, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017936", "url": "https://www.ensembl.org/id/ENSBTAG00000017936" } ] } } ], "crossref": [ { "id": "E1BG61", "url": "https://alphafold.ebi.ac.uk/entry/E1BG61", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017936", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017936", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09628", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09628", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46902:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46902:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03351", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03351", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BCL2", "url": "https://www.uniprot.org/uniprotkb/E1BCL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BCL2-1", "url": "https://www.uniprot.org/uniprotkb/E1BCL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG61", "url": "https://www.uniprot.org/uniprotkb/E1BG61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG61-1", "url": "https://www.uniprot.org/uniprotkb/E1BG61-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGGGRRNGEKDGGRDSPAEEVRMLGRSRGSGRERGCAAWAGRRRVRAAPRLRGLQAGGGRVLAATQSRPRARGAPAAARAAWLRDPCAAMARSRRSWAQLLLLLLAGPAACAASPADDGAGPGGRGPRGRARGDSSADETVPRHDSSYGTFAGEFYDLRYLSEEGYPFPTAPPVDPFAKIKVDDCGKTKGCFRYGKPGCNAETCDYFLSYRMIGADVEFELSADTDGWVAVGFSSDKKMGGDDVMACVHDDNGRVRIQHFYNVGQWAKEIQRNPARDEEGVFENNRVTCRFKRPVNVPRDETIVDLHLSWYYLFAWGPAIQGSITRHDIDSPPTSERVVSIYKYEDIFMPSAAYQTFSSPFCLLLIVALTFYLLMGTP", "length": 379, "header": "tr|E1BG61-1|E1BG61_BOVIN Isoform 1 of Ferric chelate reductase 1 like OS=Bos taurus OX=9913 GN=FRRS1L PE=4 SV=3 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"ENSBTAP00000047556.4", "url": "https://www.ensembl.org/id/ENSBTAP00000047556.4" } ] } }, { "isoform_ac": "E1BG61-1", "url": "https://www.uniprot.org/uniprotkb/E1BG61/entry#E1BG61-1", "sequence": { "sequence": "MEGGGRRNGEKDGGRDSPAEEVRMLGRSRGSGRERGCAAWAGRRRVRAAPRLRGLQAGGGRVLAATQSRPRARGAPAAARAAWLRDPCAAMARSRRSWAQLLLLLLAGPAACAASPADDGAGPGGRGPRGRARGDSSADETVPRHDSSYGTFAGEFYDLRYLSEEGYPFPTAPPVDPFAKIKVDDCGKTKGCFRYGKPGCNAETCDYFLSYRMIGADVEFELSADTDGWVAVGFSSDKKMGGDDVMACVHDDNGRVRIQHFYNVGQWAKEIQRNPARDEEGVFENNRVTCRFKRPVNVPRDETIVDLHLSWYYLFAWGPAIQGSITRHDIDSPPTSERVVSIYKYEDIFMPSAAYQTFSSPFCLLLIVALTFYLLMGTP", "length": 379, "header": "tr|E1BG61-1|E1BG61_BOVIN Isoform 1 of Ferric chelate reductase 1 like OS=Bos taurus OX=9913 GN=FRRS1L PE=4 SV=3 CANONICAL=E1BG61-1" }, "locus": { "chromosome": "8", "start_pos": 98723060, "end_pos": 98701325, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023851.4", "url": "https://www.ensembl.org/id/ENSBTAT00000023851.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023851.4", "url": "https://www.ensembl.org/id/ENSBTAP00000023851.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of glutamate receptor signaling pathway", "id": "GO:1900449", "url": 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"table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDQ6-1", "uniprot_ac": "E1BDQ6", "uniprot_id": "E1BDQ6_BOVIN", "mass": { "chemical_mass": 24002.0, "monoisotopic_mass": 24002.0 }, "refseq": {}, "gene_names": [ { "name": "NME5", "type": "recommended", "evidence": [ { "id": "E1BDQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDQ6" } ] } ], "protein_names": [ { "name": "Nucleoside diphosphate kinase 5", "type": "recommended", "evidence": [ { "id": "E1BDQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDQ6/entry#names_and_taxonomy" } ] }, { "name": "Putative 3'-5'-DNA exonuclease NDK5", "type": "synonym", "evidence": [ { "id": "E1BDQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDQ6/entry#names_and_taxonomy" } ] }, { "name": "Radial spoke head protein 23 homolog", "type": "synonym", "evidence": [ { "id": "E1BDQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDQ6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Functions as part of axonemal radial spoke complexes, which play an important part in the motility of sperm and cilia. In vitro, does not display nucleoside diphosphate kinase (NDPK) activity. Exhibits a 3'-5'-DNA exonuclease activity that removes single nucleotides from the 3' terminus of single-stranded DNA substrates and digests overhanging mismatched 3' termini from double-stranded DNA substrates, possibly participating in DNA nucleolytic processing. Confers protection from cell death mediated by BAX and alters the cellular levels of several antioxidant enzymes, including GPX5. Might be involved in spermiogenesis by enhancing the ability of late-stage spermatids to eliminate reactive oxygen species.", "evidence": [ { "database": "UniProtKB", "id": "E1BDQ6", "url": "https://www.uniprot.org/uniprotkb/E1BDQ6#function" }, { "database": "UniProtKB", "id": "ARBA00094196", "url": "https://www.uniprot.org/uniprotkb/ARBA00094196#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDQ6", "url": "https://www.uniprot.org/uniprotkb/E1BDQ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NME5", "url": "https://www.uniprot.org/uniprotkb/E1BDQ6", "locus": { "chromosome": "7", "start_pos": 49530486, "end_pos": 49582299, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008752", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR007858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BDQ6", "url": "https://www.orthodb.org/?gene=E1BDQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46161:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46161:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00009fqr", "url": "https://www.rcsb.org/structure/pdb_00009fqr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.rcsb.org/structure/9FQR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05186", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05186", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BDQ6", "url": "https://www.uniprot.org/uniprotkb/E1BDQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDQ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BDQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILRSGFTIVQRRKLHLSPEHCSNFYVEQYGKMFFPNLTAYMSSGPLVAMILARYNAISYWKELLGPSNSLVAKETHPDSLRAIYGTDELRNALHGSNDFAAAEREIRFMFPAVIVEPIPVGQAAKDYLNLYVTPTLLKGLTELCKQKPADPFIWLADWLLKNNPNKPKLCHHPVAESY", "length": 211, "header": "tr|E1BDQ6-1|E1BDQ6_BOVIN Isoform 1 of Nucleoside diphosphate kinase 5 OS=Bos taurus OX=9913 GN=NME5 PE=1 SV=3 CANONICAL=E1BDQ6-1" }, "isoforms": [ { "isoform_ac": "E1BDQ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BDQ6/entry#E1BDQ6-1", "sequence": { "sequence": "MELSMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILRSGFTIVQRRKLHLSPEHCSNFYVEQYGKMFFPNLTAYMSSGPLVAMILARYNAISYWKELLGPSNSLVAKETHPDSLRAIYGTDELRNALHGSNDFAAAEREIRFMFPAVIVEPIPVGQAAKDYLNLYVTPTLLKGLTELCKQKPADPFIWLADWLLKNNPNKPKLCHHPVAESY", "length": 211, "header": "tr|E1BDQ6-1|E1BDQ6_BOVIN Isoform 1 of Nucleoside diphosphate kinase 5 OS=Bos taurus OX=9913 GN=NME5 PE=1 SV=3 CANONICAL=E1BDQ6-1" }, "locus": { "chromosome": "7", "start_pos": 49581666, "end_pos": 49553123, "strand": "+", "evidence": [ { "database": 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"MLPWGLSCLSALGAVGTALLGAGLLLSLAQHLWTLRWTLSRDRASALPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTVLLGEHRLVRSQWPQSAHILLGSHTLLGAVGESHRQRRKILARAFSRAALECYVPRLQRALRREVRSWCAARGPVAVYEAAKALTFRMAARILLGLRLDEAQCSELARTFEQFVENLFSLPLDVPFSGLRKGIRARDQLHRHLEEAIAQKLLEDKTAVEPGDALDGIIHSTRELGHELSVQELKESAVELLFAAFSTTASASTSLVLLLLQHPAAIAKIQQELAAQGLGRACGCAPAASGGGAGPPPDCGCEPDLSLATLGHLRYVGCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWNVMYSIRDTHETAAVYRSPPEGFDPERFGTAGDDALGAAGRFHYIPFGGGARSCLGQELAQTVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLASPAAQDGQRL", "length": 523, "header": "tr|E1BDT5-1|E1BDT5_BOVIN Isoform 1 of Cytochrome P450 family 26 subfamily C member 1 OS=Bos taurus OX=9913 GN=CYP26C1 PE=3 SV=1 CANONICAL=E1BDT5-1" }, "locus": { "chromosome": "26", "start_pos": 14411373, "end_pos": 14403428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056396.4", "url": "https://www.ensembl.org/id/ENSBTAT00000056396.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050244.2", "url": "https://www.ensembl.org/id/ENSBTAP00000050244.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539048", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539048", "resource": "KEGG Pathway" }, { "id": "R-BTA-211916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-211916", "resource": "Reactome", "description": "Vitamins" }, { "id": "R-BTA-5365859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5365859", "resource": "Reactome", "description": "RA biosynthesis pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IE06-1", "protein_name": "Cytochrome P450 26C1", "gene_name": "LOC100755258", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"MPAGLCWPAAAALALLFLALLLALCRHLWALRWSLSRDRASALPLPKGSMGWPFFGETLHWLLQGSRFHSSRRERYGNVFKTHLLGRPVVRVTGAENVRKILLGEHTLVSAQWPQSTQILLGSHTLLGSTGDLHRQRRKILARVFCRAALESYLPRIQKVVSWELRGWCMQPGSIAVYSSAKTLTFRIAAQILLGLRLEEKQFKDLAKTFEQLVENLFSLPLNVPFSGLRKGIKARDMLHEFMERAIQEKLQRAISEEHSDALDFIINSAKEHGKEFTMQELKESAIELIFAAFFTTASASTSLILLLLKHPSAIEKIRQELVSHELYPQHQNCPMAPCPGTGRDSEQQLLTTASDAHEDQLQLPDLTEETELGGGCSPNLPALLEPMHPPSSPQPRGCRCPLDISLEQLSRLRYLDCVVKEVLRVLPPVSGGYRTALQTFELDGYQIPKGWSVMYSIRDTHETAAIYQSPPGGFDPDRFNVTHLEAAGRFHYIPFGGGARSCIGKELAQAILKLLAIELVTTARWELATPTFPAMQTVPIVHPVDGLQLYFHPLWPSHGGEA", "length": 563 }, "evidence": [ { "id": "E1BDT5", "url": "https://omabrowser.org/oma/group/E1BDT5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B2RXA7-1", "protein_name": "Cytochrome P450 26C1", "gene_name": "Cyp26c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISWGLSCLSVLGAAGTTLLCAGLLLGLAQQLWTLRWTLSRDWASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRQRRKVLARVFSRSSLEQFVPRLQGALRREVRSWCAAQRPVAVYQAAKALTFRMAARILLGLQLDEARCTELAHTFEQLVENLFSLPLDVPFSGLRKGIRARDQLYEHLDEAVAEKLQEKQTAEPGDALLLIINSARELGHEPSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAITKIQQELSAQGLGRACTCTPRASGSPPDCGCEPDLSLAMLGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESGDARGSGGRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPVMQTVPIVHPVDGLLLFFHPLPTSGAGDGLPF", "length": 518 }, "evidence": [ { "id": "E1BDT5", "url": "https://omabrowser.org/oma/group/E1BDT5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4AAL3-1", "protein_name": "Cytochrome P450, family 26, subfamily C, polypeptide 1", "gene_name": "Cyp26c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSWGLSCLSMLGAAGTALLCAGLLLGLAQQLWTLRWTLSRDWASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGERHRQRRKVLARVFSRPALEQFVPRLQEALRREVRSWCAAQRPVAVYQAAKALTFRMAARILLGLQLDEARCTELAQTFERLVENLFSLPLDVPFSGLRKGIRARDQLYQHLDEVIAEKLREELTAEPGDALHLIINSARELGRELSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAIAKIQQELSAQGLGSPCSCAPRASGSRPDCSCEPDLSLAVLGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESEDARGSGGRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPVMQTVPIVHPVDGLLLLFHPLPTLGAGDGSPF", "length": 518 }, "evidence": [ { "id": "E1BDT5", "url": "https://omabrowser.org/oma/group/E1BDT5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SC84-1", "protein_name": "Cytochrome P450 family 26 subfamily C member 1", "gene_name": "CYP26C1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFPWGLSSLSVLGAAGTALLCAGLLLSLAQHLWTLRWTLSRDRSSALPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRQRRKILARVFSRAALERYVPRLQGALRREVRSWCVARGPVAVYEAAKALTFRMAARILLGLRLEEEQCSELARTFERFVENLFSLPLDVPFSGLRKGIRARDQLHRHLEEAIAEKLHEDKAAEPGDALAGIIHSTRELGQELSVQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIVKIRQELAAQGLGRACGCAPGASGGGAGPRPDCGCEPDLSLAALGRLRYVGCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWNVMYSIRDTHETAAVYRSPPEGFDPERFHTAGEDARGAAGRFHYIPFGGGARSCLGQELAQTVLQLLAVELVRTARWELATPSFPAMQTVPIVHPVDGLRLFFYPLAPSAAQDGRRL", "length": 522 }, "evidence": [ { "id": "E1BDT5", "url": "https://omabrowser.org/oma/group/E1BDT5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q42569-1", "protein_name": "3beta,22alpha-dihydroxysteroid 3-dehydrogenase", "gene_name": "CYP90A1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAFTAFLLLLSSIAAGFLLLLRRTRYRRMGLPPGSLGLPLIGETFQLIGAYKTENPEPFIDERVARYGSVFMTHLFGEPTIFSADPETNRFVLQNEGKLFECSYPASICNLLGKHSLLLMKGSLHKRMHSLTMSFANSSIIKDHLMLDIDRLVRFNLDSWSSRVLLMEEAKKITFELTVKQLMSFDPGEWSESLRKEYLLVIEGFFSLPLPLFSTTYRKAIQARRKVAEALTVVVMKRREEEEEGAERKKDMLAALLAADDGFSDEEIVDFLVALLVAGYETTSTIMTLAVKFLTETPLALAQLKEEHEKIRAMKSDSYSLEWSDYKSMPFTQCVVNETLRVANIIGGVFRRAMTDVEIKGYKIPKGWKVFSSFRAVHLDPNHFKDARTFNPWRWQSNSVTTGPSNVFTPFGGGPRLCPGYELARVALSVFLHRLVTGFSWVPAEQDKLVFFPTTRTQKRYPIFVKRRDFAT", "length": 472 }, "evidence": [ { "id": "E1BDT5", "url": "https://omabrowser.org/oma/group/E1BDT5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6V0L0-1", "protein_name": "Cytochrome P450 26C1", "gene_name": "CYP26C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL", "length": 522 }, "evidence": [ { "id": "E1BDT5", "url": "https://omabrowser.org/oma/group/E1BDT5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "retinoic acid 4-hydroxylase activity", "id": "GO:0008401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008401", "evidence": [ { "database": "UniProtKB", "id": "E1BDT5", "url": "https://www.uniprot.org/uniprotkb/E1BDT5" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "E1BDT5", "url": "https://www.uniprot.org/uniprotkb/E1BDT5" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "E1BDT5", "url": "https://www.uniprot.org/uniprotkb/E1BDT5" } ], "pmid": "" }, { "name": "retinoic acid binding", "id": "GO:0001972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001972", "evidence": [ { "database": "UniProtKB", "id": "E1BDT5", "url": "https://www.uniprot.org/uniprotkb/E1BDT5" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "E1BDT5", "url": "https://www.uniprot.org/uniprotkb/E1BDT5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BDT5", "url": "https://www.uniprot.org/uniprotkb/E1BDT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "E1BDT5", "url": "https://www.uniprot.org/uniprotkb/E1BDT5" } ], "pmid": "" }, { "name": "retinoic acid catabolic process", "id": "GO:0034653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034653", "evidence": [ { "database": "UniProtKB", "id": "E1BDT5", "url": "https://www.uniprot.org/uniprotkb/E1BDT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "51984", "name": "", "equation": "all-trans-retinoate + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-4-hydroxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BHJ4-1" ], "evidence": [ { "id": "51984", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51984" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BHJ4", "gene_name": "CYP26B1", "activity": [ { "ec_number": "1.14.13.-", "activity": "", "evidence": [ { "id": "E1BHJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHJ4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDT5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 523, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDT5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDT5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BDU1-1", "uniprot_ac": "E1BDU1", "uniprot_id": "E1BDU1_BOVIN", "mass": { "chemical_mass": 35239.0, "monoisotopic_mass": 35239.0 }, "refseq": { "ac": "XP_003586481", "name": "olfactory receptor 2K2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586481" }, "gene_names": [ { "name": "OR2K2", "type": "recommended", "evidence": [ { "id": "E1BDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDU1" } ] }, { "name": "OR2K2", "type": "synonym", "evidence": [ { "id": "XP_003586481", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586481" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDU1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2K2", "type": "synonym", "evidence": [ { "id": "XP_003586481", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586481" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BDU1", "url": "https://www.uniprot.org/uniprotkb/E1BDU1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDU1", "url": "https://www.uniprot.org/uniprotkb/E1BDU1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2K2", "url": "https://www.uniprot.org/uniprotkb/E1BDU1", "locus": { "chromosome": "8", "start_pos": 100789221, "end_pos": 100790171, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010686", "url": "https://www.ensembl.org/id/ENSBTAG00000010686" } ] } } ], "crossref": [ { "id": "E1BDU1", "url": "https://alphafold.ebi.ac.uk/entry/E1BDU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "539574", "url": "https://www.ncbi.nlm.nih.gov/gene/539574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539574", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539574", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IPMLFIC", "url": "https://omabrowser.org/oma/group/IPMLFIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BDU1", "url": "https://www.orthodb.org/?gene=E1BDU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003586481", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586481", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BDU1", "url": "https://www.uniprot.org/uniprotkb/E1BDU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDU1-1", "url": "https://www.uniprot.org/uniprotkb/E1BDU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGENLTSWSFFFLEGFSRYPKLEIVLFIFSLFVYLITLLGNSILILITVVDSRLQTPMYLFLGNLSFMDICYTSASIPTLLVNLLSSQKTIVFSGCAVQMYLSLAMGSTECVLLAVMAYDRYVAICSPLRYPVIMNRQVCVQMATISWVTGSLTALLETSFALRIPRCGNLIDHFTCEILAVLKLACTRSLLMDTVMLVISVLLLPIPMLLICISYVFILSTILRISSAEGRNKAFSTCGAHLTVVILYYGAALSMYLKPSSSGSQEIDKIISLLYGVLTPMLNPIIYSLRNKEVKDAVKKVLGKMYLQQTQEHL", "length": 316, "header": "tr|E1BDU1-1|E1BDU1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2K2 PE=3 SV=2 CANONICAL=E1BDU1-1" }, "isoforms": [ { "isoform_ac": "E1BDU1-1", "url": "https://www.uniprot.org/uniprotkb/E1BDU1/entry#E1BDU1-1", "sequence": { "sequence": "MQGENLTSWSFFFLEGFSRYPKLEIVLFIFSLFVYLITLLGNSILILITVVDSRLQTPMYLFLGNLSFMDICYTSASIPTLLVNLLSSQKTIVFSGCAVQMYLSLAMGSTECVLLAVMAYDRYVAICSPLRYPVIMNRQVCVQMATISWVTGSLTALLETSFALRIPRCGNLIDHFTCEILAVLKLACTRSLLMDTVMLVISVLLLPIPMLLICISYVFILSTILRISSAEGRNKAFSTCGAHLTVVILYYGAALSMYLKPSSSGSQEIDKIISLLYGVLTPMLNPIIYSLRNKEVKDAVKKVLGKMYLQQTQEHL", "length": 316, "header": "tr|E1BDU1-1|E1BDU1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2K2 PE=3 SV=2 CANONICAL=E1BDU1-1" }, "locus": { "chromosome": "8", "start_pos": 100790171, "end_pos": 100789224, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055370.3", "url": "https://www.ensembl.org/id/ENSBTAT00000055370.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050237.2", "url": "https://www.ensembl.org/id/ENSBTAP00000050237.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539574", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539574", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LG45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100757736", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQGENVTVWSFFFLEGFSRYPRLEIVLFVFSLVMYLVTILGNSTLILITVLDSHLQTPMYLFLGNLSFMDICYTSASIPTLLVNLLSSKKTIVFSGCVVQMYLSLSMGSTECILLAVMAYDRYVAICNPLRYPIIMNRQVCVQMATVSWVTGCLTALLETSFALKVPLCGNVIDHFTCEILAVLKLACMSSLLMDMVMLVVSILLLPIPMLLICISYGFILSTILRISSTEGRNKAFSTCGAHLTVVILYFGAALSMYLKPSSSNSQQIDKIISLLYGVLTPMLNPIIYSLRNKEVKDAVKKLLGKVSLAPSM", "length": 313 }, "evidence": [ { "id": "E1BDU1", "url": "https://omabrowser.org/oma/group/E1BDU1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A2AM35-1", "protein_name": "Olfactory receptor", "gene_name": "Or2k2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGENVTVWSLFFLEGFSRYPRLEIVLFVFSLVMYLVTILGNCTLILITVLDSRLQTPMYLFLGNLSFMDICYTSASIPTLLVNLLSSKKTIIFSGCAVQMYLSLSMGSTECILLAVMAYDRYVAICNPLRYPIIMNRQVCVQMATISWVTGCLTALLETSFALQIPLCGNIINHFTCEILAVLKLACVSSLLMDLVMLVVSILLLPIPMLLICISYGFILSTILRISSTEGRNKAFSTCGAHLTVVILYYGAALSMYLKPSSSNSQEIDKIISLLYGVLTPMLNPIIYSLRNKEVKDAMIKLLGKVPLAPSV", "length": 313 }, "evidence": [ { "id": "E1BDU1", "url": "https://omabrowser.org/oma/group/E1BDU1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4AAX4-1", "protein_name": "Olfactory receptor", "gene_name": "Or2k2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGENVTVWSLFFLEGFSRYPRLEIVLFVFSLVMYLVTILGNSTLILITVLDSHLQTPMYLFLGNLSFMDICYTSASIPTLLVNLLSSKKTIIFSGCAVQMYLSLSMGSTECILLAVMAYDRYVAICNPLRYPIIMSRHVCGQMAAISWVTGCLTALLETSCALQIPLCGNVIDHFTCEILAVLKLACVSSLLVDMVMLVVSILLLPIPMLLICISYGFILSTILRIGSTEGRNKAFSTCGAHLTVVILYYGAALSMYLKPSSSNSQEIDKIISLLYGVLTPMLNPIIYSLRNKEVKDAVKKLLGKVPLAPGM", "length": 313 }, 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initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377714" }, "gene_names": [ { "name": "OR52AB2", "type": "recommended", "evidence": [ { "id": "E1BDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDV2" } ] }, { "name": "OR52AB2", "type": "synonym", "evidence": [ { "id": "NP_001377714", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377714" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDV2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 52 subfamily AB member 2", "type": "synonym", "evidence": [ { "id": "NP_001377714", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377714" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BDV2", "url": "https://www.uniprot.org/uniprotkb/E1BDV2#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377714", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377714" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BDV2", "url": "https://www.uniprot.org/uniprotkb/E1BDV2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDV2", "url": "https://www.uniprot.org/uniprotkb/E1BDV2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR52AB2", "url": "https://www.uniprot.org/uniprotkb/E1BDV2", "locus": {} } ], "crossref": [ { "id": "E1BDV2", "url": "https://alphafold.ebi.ac.uk/entry/E1BDV2", 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}, { "id": "E1BDV2-1", "url": "https://www.uniprot.org/uniprotkb/E1BDV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASINMSYLNPRTVILIGIPGLQHMQFWIGFPFFAVCLVALLGNIILLIIIPMERSLHQPMYIFLAVLAATDIGLCAAIAPKMLAIFWFRSYSMAFDTCLAQLFFIHALQCMESGILLAMALDRYIAICDPLRHTSILTPSVLGRMVVIVAIRATVLVGLLPILIKRLHRFHSTVIAHSYCEHMAVVKLAAEDIRVNNTCGLFVGFTILGFDMIFILISYTLIFQAVLRLHQKEARLKAFNTCTAHIFVFLEFYILAFFSFFSHRFGHVVPSTHILLSTIYLLVPPALNPIVYGVKNKVICKHVAQVLLLNHGSQQ", "length": 316, "header": "tr|E1BDV2-1|E1BDV2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR52AB2 PE=3 SV=3 CANONICAL=E1BDV2-1" }, "isoforms": [ { "isoform_ac": "E1BDV2-1", "url": "https://www.uniprot.org/uniprotkb/E1BDV2/entry#E1BDV2-1", "sequence": { "sequence": 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{ "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512021", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512021", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QGCPTHR", "url": "https://omabrowser.org/oma/group/QGCPTHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BDY4", "url": "https://www.orthodb.org/?gene=E1BDY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12845", "database": "PANTHER", 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CANONICAL=E1BDY4-1" }, "locus": { "chromosome": "19", "start_pos": 27934126, "end_pos": 27925923, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044645.6", "url": "https://www.ensembl.org/id/ENSBTAT00000044645.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042124.4", "url": "https://www.ensembl.org/id/ENSBTAP00000042124.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 747, "start_aa": "Thr", "end_pos": 747, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr747", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" 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"common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BDY4", "url": "https://www.uniprot.org/uniprotkb/E1BDY4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BDY4", "url": "https://www.uniprot.org/uniprotkb/E1BDY4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BDY4", "url": "https://www.uniprot.org/uniprotkb/E1BDY4" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "E1BDY4", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "E1BDY4", "url": "https://www.uniprot.org/uniprotkb/E1BDY4" } ], "pmid": "" }, { "name": "negative regulation of synapse maturation", "id": "GO:2000297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000297", "evidence": [ { "database": "UniProtKB", "id": "E1BDY4", "url": "https://www.uniprot.org/uniprotkb/E1BDY4" } ], "pmid": "" }, { "name": "regulation of postsynapse assembly", "id": "GO:0150052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150052", "evidence": [ { "database": "UniProtKB", "id": "E1BDY4", "url": "https://www.uniprot.org/uniprotkb/E1BDY4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E1BDY4", "url": "https://www.uniprot.org/uniprotkb/E1BDY4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BDY4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 847, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BDY4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BDY4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 747 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"E1BE12_BOVIN", "mass": { "chemical_mass": 113401.0, "monoisotopic_mass": 113401.0 }, "refseq": { "ac": "XP_005222730", "name": "contactin-4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222730" }, "gene_names": [ { "name": "CNTN4", "type": "recommended", "evidence": [ { "id": "E1BE12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE12" } ] }, { "name": "CNTN4", "type": "synonym", "evidence": [ { "id": "XP_005222730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222730" } ] } ], "protein_names": [ { "name": "Contactin 4", "type": "synonym", "evidence": [ { "id": "E1BE12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE12/entry#names_and_taxonomy" } ] }, { "name": "contactin-4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005222730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222730" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BE12", "url": "https://www.uniprot.org/uniprotkb/E1BE12" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CNTN4", "url": "https://www.uniprot.org/uniprotkb/E1BE12", "locus": { "chromosome": "22", "start_pos": 23254010, "end_pos": 24279957, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000033225", "url": "https://www.ensembl.org/id/ENSBTAG00000033225" } ] } } ], "crossref": [ { "id": "E1BE12", "url": "https://alphafold.ebi.ac.uk/entry/E1BE12", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000033225", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000033225", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05853", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05853", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "521772", "url": "https://www.ncbi.nlm.nih.gov/gene/521772", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521772", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521772", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RIQGYEX", "url": "https://omabrowser.org/oma/group/RIQGYEX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BE12", "url": "https://www.orthodb.org/?gene=E1BE12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005222730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222730", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BE12", "url": "https://www.uniprot.org/uniprotkb/E1BE12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE12-1", "url": "https://www.uniprot.org/uniprotkb/E1BE12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLPWELLVLQSFMLCLADDYTLHGPIFIQEPSHVMFPLDSEEKKVKLSCEVKGNPKPHIRWKLNGTDVDIGMDFRYSVVEGSLLINNPNKTQDAGMYQCIATNSFGTIVSREAKLQFAYLENFKPRTRSTVSVRQGQGMVLLCGPPAHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNQKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGTTVKLECFALGNPVPTIIWRRADGKPIATKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVAKGQLTFYAQPNWSQKINDIHVAIEENVFWECKANGRPKPTYRWLKNGEPLLTRDRIHIEQGTLNITIVNLSDAGMYQCVAENKHGVIFSSAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVHTWKKGRDVLKENERITISEDGSLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTKVMVPPSSMDVTVGESIVLPCQVTHDHSLNIVFTWSFNGRLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYICMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVNTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVRPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPMEKNRGRIQGYEVKYWRHDDKEENARKIRTIGNQTSTKITNLKGSALYHLAVKAYNSAGTGPASATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWSRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGAGPSTSNACTLSAISTIMISLTARSSL", "length": 1026, "header": "tr|E1BE12-1|E1BE12_BOVIN Isoform 1 of Contactin 4 OS=Bos taurus OX=9913 GN=CNTN4 PE=3 SV=3 CANONICAL=E1BE12-1" }, "isoforms": [ { "isoform_ac": "E1BE12-1", "url": "https://www.uniprot.org/uniprotkb/E1BE12/entry#E1BE12-1", "sequence": { "sequence": "MRLPWELLVLQSFMLCLADDYTLHGPIFIQEPSHVMFPLDSEEKKVKLSCEVKGNPKPHIRWKLNGTDVDIGMDFRYSVVEGSLLINNPNKTQDAGMYQCIATNSFGTIVSREAKLQFAYLENFKPRTRSTVSVRQGQGMVLLCGPPAHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNQKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGTTVKLECFALGNPVPTIIWRRADGKPIATKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVAKGQLTFYAQPNWSQKINDIHVAIEENVFWECKANGRPKPTYRWLKNGEPLLTRDRIHIEQGTLNITIVNLSDAGMYQCVAENKHGVIFSSAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVHTWKKGRDVLKENERITISEDGSLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTKVMVPPSSMDVTVGESIVLPCQVTHDHSLNIVFTWSFNGRLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYICMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVNTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVRPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPMEKNRGRIQGYEVKYWRHDDKEENARKIRTIGNQTSTKITNLKGSALYHLAVKAYNSAGTGPASATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWSRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGAGPSTSNACTLSAISTIMISLTARSSL", "length": 1026, "header": "tr|E1BE12-1|E1BE12_BOVIN Isoform 1 of Contactin 4 OS=Bos taurus OX=9913 GN=CNTN4 PE=3 SV=3 CANONICAL=E1BE12-1" }, "locus": { "chromosome": "22", "start_pos": 23781559, "end_pos": 23254713, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000060980.5", "url": "https://www.ensembl.org/id/ENSBTAT00000060980.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053677.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053677.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:521772", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521772", "resource": "KEGG Pathway" }, { "id": "R-BTA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZEQ2-1", "protein_name": "Contactin 4", "gene_name": "CNTN4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLLWELLVLQSFMVCLADDNMLHGPVFLQEPSSVIFPLDSEEKKVKLNCEVKGNPRPTIGWKLNGTNIDIGMDYRYSMVEGNLLINNPNRTQDTGTYQCVATNPFGRIISREAKLQFAYLENFKTRVRSTVSVRQGQGMVLLCGPPPHSGELTYAWIFNEYPSFVHQDNRRFVSQETGNLYIAKVEASDVGNYTCVVTNTVTNSRVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPSAKGTAVKLECFALGNPVPTISWRRADGKQIPRKARRHRSNGLLEIPNFQQEDAGLYECVAENVRGKNVARGQLTFYAQPNWIQKISDVHAAIEENVFWECHASGRPKPSYRWLKDGEPLLPQGRVQIEQGSLTIRNVSLSDAGMYQCVAENRHGTIFASAELSVIAVGPDFSKTLLKKLTLVKVGGEVIIECKPKASPRPTYSWKKGKDILRENERITVLDDGSLRIVNVTKSDTGSYTCVATNHFGTASSTGSLVVKDPTRVMVSPFSMDVTVGESIVLPCQVSHDHSLDIVFTWSFNGHLIDFEKDGDHFERVGGQDSAGDLMIRSIQLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPPEDVTIDEITDTTAQLSWRPGADNHSPITMYVVQARTPFSVGWQAVSTVPEVIDGKTFTATVVGLNPWVEYEFRVVAANLIGIGEPSRPSENRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGGGFGYVVAFRPFGTISWMQTVVASPDASRYVFRNESLPPFSPYEVKVGVYNNKGEGSFSPVTVVYSAEEEPTKAPITVLARSLSATDIEISWAPPRENQHKGRIQGYEVRCWRHDEKEENARKIRTVGNQTSAKVTNLQGNALYHLAVKAYNTAGTGPSSAMVNVTTKKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVRGYKVLYKWNRQSSASVIETNRTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGGSSSTSNACTLSAISTIMISLTARSSL", "length": 1029 }, "evidence": [ { "id": "E1BE12", "url": "https://omabrowser.org/oma/group/E1BE12/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q62845-1", "protein_name": "Contactin-4", "gene_name": "Cntn4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLPWELLVLQSFMLCLADDYTLHGPVFVQEPSHVMFPLDSEEKKVKLSCEVKGNPKPHIRWKLNGTDVDIGMDFRYSVVEGSLLINNPNKTQDSGTYQCIATNSFGTIVSREAKLQFAYLENFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEHPSYQDNRRFVSQETGNLYIAKVEKADVGNYTCVVTNTVTSHQVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPAEKGSTVKLECFALGNPVPTILWRRADGKPIARKARRHKSSGILEIPNFQQEDAGSYECVAENSRGKNIAKGQVTFYAQPNWVQIINDIHVAMEESVFWECKANGRPKPTYRWLKNGDPLLTRERIQIEQGTLNITIVNLSDAGMYQCVAENKHGVIYASAELSVIAESPDFSRTLLKRVTLVKVGGEVVIECKPKASPRPVYTWRKGREILRENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNVVVKDPTKVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWTFNGHLIDFDKDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELVDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPHGKMIWMLTVLASADASRYVFRNESVRPFSPFEVKVGVFNNKGEGPFSPTTLVYSAEEEPTKPPASIFARSLSATDIEVFWASPIGKNRGRIQGYEVKYWRHDDKEENARKIRTVGNQTSTKITNLKGNALYHLSVKAYNSAGTGPSSAAVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNSYARGSGASTSNACTLSAISTIMISLTARSSL", "length": 1026 }, "evidence": [ { "id": "E1BE12", "url": "https://omabrowser.org/oma/group/E1BE12/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IWV2-1", "protein_name": "Contactin-4", "gene_name": "CNTN4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLPWELLVLQSFILCLADDSTLHGPIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL", 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} } ], "crossref": [ { "id": "E1BE14", "url": "https://alphafold.ebi.ac.uk/entry/E1BE14", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000044068", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044068", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "784924", "url": "https://www.ncbi.nlm.nih.gov/gene/784924", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059152", "database": "InterPro", "categories": [ "Protein 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"tr|E1BE14-1|E1BE14_BOVIN Isoform 1 of von Willebrand factor C domain containing 2 OS=Bos taurus OX=9913 GN=VWC2 PE=4 SV=3 CANONICAL=E1BE14-1" }, "locus": { "chromosome": "4", "start_pos": 6118118, "end_pos": 5991207, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061274.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061274.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053671.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053671.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 139, "start_aa": "Thr", "end_pos": 139, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr139", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:784924", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784924", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BVA8-1", "protein_name": "von Willebrand factor C domain containing 2", "gene_name": "VWC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSSTAMAIGALSSSLLVTCCLMVALCSSTIPLQKLARAQDKQEIKASQEKRDHASARDSQAGAGKVGEIGRSGREEGGRDWKGKGGRNYSSKESWTKQKQAWSSQGTGGKPASVPAQEQQDMAAEAPRPAEASSLPAAVASATPEPLEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCMQPECPRLHPRCVHVDTTQCCPQCKERKNYCEFRGKTYQSLEEFMVSPCEKCRCEASGEVLCTVSACPQTECVDPVYEPDQCCPICKNGTCAYAKSGAGCRENRHNSIECSCGFVEGEEEEKLQRVSGKVVKVTDTVASVGPNCFAETTVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECKQI", "length": 383 }, "evidence": [ { "id": "E1BE14", "url": "https://omabrowser.org/oma/group/E1BE14/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SF29-1", "protein_name": "von Willebrand factor C domain containing 2", "gene_name": "VWC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPSSTAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHASRDGPGRVSELGRPARDEGGGGRDWKGKGGRGLTSREAWSRQKQAWPAQGGGAKAGDLQVRPRGDTPHEEPPAASAQDAAGSDPGPTLEPPEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCRCEASGEVLCAVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQM", "length": 325 }, "evidence": [ { "id": "E1BE14", "url": "https://omabrowser.org/oma/group/E1BE14/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0RB53-1", "protein_name": "von Willebrand factor C domain containing 2", "gene_name": "Vwc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSSSAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHASRDSPGRVSELGRASRDEGSSARDWKSKGSRALSGREAWSKQKQAWAAQSGSAKAADWQVRPRGDTPQGEPPAAAQEAISLELMPTPELPEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQM", "length": 324 }, "evidence": [ { "id": "E1BE14", "url": "https://omabrowser.org/oma/group/E1BE14/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2TAL6-1", "protein_name": "Brorin", "gene_name": "VWC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSSTAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHASRDGPGRVNELGRPARDEGGSGRDWKSKSGRGLAGREPWSKLKQAWVSQGGGAKAGDLQVRPRGDTPQAEALAAAAQDAIGPELAPTPEPPEEYVYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQM", "length": 325 }, "evidence": [ { "id": "E1BE14", "url": "https://omabrowser.org/oma/group/E1BE14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C8N3-1", "protein_name": "Brorin", "gene_name": "Vwc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSSSAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHASRDSPGRVSELGRASRDEGSSARDWKSKGSRALSGREAWSKQKQAWAAQGGSAKAADWQVRPRGDTPQGEPPAAAQEAISLELVPTPELPEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDNSQCCPQCKEKKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQM", "length": 324 }, "evidence": [ { "id": "E1BE14", "url": "https://omabrowser.org/oma/group/E1BE14/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BE14", "url": "https://www.uniprot.org/uniprotkb/E1BE14" } ], "pmid": "" }, { "name": "extrinsic component of postsynaptic membrane", "id": "GO:0098890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098890", "evidence": [ { "database": "UniProtKB", "id": "E1BE14", "url": "https://www.uniprot.org/uniprotkb/E1BE14" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BE14", "url": "https://www.uniprot.org/uniprotkb/E1BE14" } ], "pmid": "" }, { "name": "AMPA glutamate receptor complex", "id": "GO:0032281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032281", "evidence": [ { "database": "UniProtKB", "id": "E1BE14", "url": "https://www.uniprot.org/uniprotkb/E1BE14" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "E1BE14", "url": "https://www.uniprot.org/uniprotkb/E1BE14" } ], "pmid": "" }, { "name": "interstitial matrix", "id": "GO:0005614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614", "evidence": [ { "database": "UniProtKB", "id": "E1BE14", "url": "https://www.uniprot.org/uniprotkb/E1BE14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "E1BE14", "url": "https://www.uniprot.org/uniprotkb/E1BE14" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "E1BE14", "url": "https://www.uniprot.org/uniprotkb/E1BE14" } ], "pmid": "" }, { "name": "neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0099645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099645", "evidence": [ { "database": "UniProtKB", "id": "E1BE14", "url": "https://www.uniprot.org/uniprotkb/E1BE14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BE14-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 326, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BE14-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BE14" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BE14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE14" }, { "id": "PS50184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFC", "eco_id": "ECO_0000259", "start_pos": 217, "end_pos": 275, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 139 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BE20-1", "uniprot_ac": "E1BE20", "uniprot_id": "E1BE20_BOVIN", "mass": { "chemical_mass": 40653.0, "monoisotopic_mass": 40653.0 }, "refseq": { "ac": "NP_001192938", "name": "clavesin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192938" }, "gene_names": [ { "name": "CLVS1", "type": "recommended", "evidence": [ { "id": "E1BE20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE20" } ] }, { "name": "CLVS1", "type": "synonym", "evidence": [ { "id": "NP_001192938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192938" } ] }, { "name": "RLBP1L1", "type": "synonym", "evidence": [ { "id": "NP_001192938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192938" } ] } ], "protein_names": [ { "name": "Clavesin-1", "type": "recommended", "evidence": [ { "id": "E1BE20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE20/entry#names_and_taxonomy" } ] }, { "name": "Retinaldehyde-binding protein 1-like 1", "type": "synonym", "evidence": [ { "id": "E1BE20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE20/entry#names_and_taxonomy" } ] }, { "name": "clavesin-1", "type": "synonym", "evidence": [ { "id": "NP_001192938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192938" } ] }, { "name": "retinaldehyde binding protein 1-like 1", "type": "synonym", "evidence": [ { "id": "NP_001192938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192938" } ] } ], "function": [ { "annotation": "Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).", "evidence": [ { "database": "UniProtKB", "id": "E1BE20", "url": "https://www.uniprot.org/uniprotkb/E1BE20#function" }, { "database": "UniProtKB", "id": "ARBA00046144", "url": "https://www.uniprot.org/uniprotkb/ARBA00046144#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BE20", "url": "https://www.uniprot.org/uniprotkb/E1BE20" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CLVS1", "url": "https://www.uniprot.org/uniprotkb/E1BE20", "locus": { "chromosome": "14", "start_pos": 27012590, "end_pos": 26854867, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000043978", "url": "https://www.ensembl.org/id/ENSBTAG00000043978" } ] } } ], "crossref": [ { "id": "E1BE20", "url": "https://alphafold.ebi.ac.uk/entry/E1BE20", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000043978", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000043978", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532808", "url": "https://www.ncbi.nlm.nih.gov/gene/532808", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532808", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532808", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DSAKMTH", "url": "https://omabrowser.org/oma/group/DSAKMTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BE20", "url": "https://www.orthodb.org/?gene=E1BE20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10174:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10174:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-432720", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432720", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192938", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192938", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BE20", "url": "https://www.uniprot.org/uniprotkb/E1BE20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE20-1", "url": "https://www.uniprot.org/uniprotkb/E1BE20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPVSFLPKHQKLSTLKGDSAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKPMKRSQSVVEAGTLKHEDKGENENTQPLLALD", "length": 354, "header": "tr|E1BE20-1|E1BE20_BOVIN Isoform 1 of Clavesin-1 OS=Bos taurus OX=9913 GN=CLVS1 PE=4 SV=3 CANONICAL=E1BE20-1" }, "isoforms": [ { "isoform_ac": "E1BE20-1", "url": "https://www.uniprot.org/uniprotkb/E1BE20/entry#E1BE20-1", "sequence": { "sequence": "MGPVSFLPKHQKLSTLKGDSAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKPMKRSQSVVEAGTLKHEDKGENENTQPLLALD", "length": 354, "header": "tr|E1BE20-1|E1BE20_BOVIN Isoform 1 of Clavesin-1 OS=Bos taurus OX=9913 GN=CLVS1 PE=4 SV=3 CANONICAL=E1BE20-1" }, "locus": { "chromosome": "14", "start_pos": 27012587, "end_pos": 26855040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061465.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061465.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053662.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053662.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532808", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532808", "resource": "KEGG Pathway" }, { "id": "R-BTA-432720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432720", "resource": "Reactome", "description": "Lysosome Vesicle Biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XF18-1", "protein_name": "Clavesin-1", "gene_name": "CLVS1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTHLQAGLSPETIEKARLELNENPDILHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQMEAFRLLAQYFQYRQLNLDMFKNFKADDPGIKRALTDGFPGVLENRDHCGRKILLLFAANWDQSRNSFIDILRAILLSLEVLIEDQELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPECLPSEFGGTLPPYDMGTWARTLLGPDYSDENEYTHTSYNAMHVKHASSSLEQEDSPKPMKRLVLLWEPPPGGLDGGRPGREGWERGCGRAGKR", "length": 336 }, "evidence": [ { "id": "E1BE20", "url": "https://omabrowser.org/oma/group/E1BE20/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6JFQ6-1", "protein_name": "Clavesin-1", "gene_name": "Clvs1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MGPVSVLPSPQSLSTWEGDLAKMTHLQAGLSPDTIEKARLELNENPDILHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTHTSYNAMHVKHTCSNLERECSPKPMKRSQSVVEAGTLKHEEKGENENTQPLLALD", "length": 354 }, "evidence": [ { "id": "E1BE20", "url": "https://omabrowser.org/oma/group/E1BE20/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "evidence": [ { "database": "UniProtKB", "id": "E1BE20", "url": "https://www.uniprot.org/uniprotkb/E1BE20" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": 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"url_external": "https://alphafold.ebi.ac.uk/entry/E1BE20" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BE20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE20" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 118, "end_pos": 279, "start_aa": "Ile", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"uniprot_id": "E1BE22_BOVIN", "mass": { "chemical_mass": 47017.0, "monoisotopic_mass": 47017.0 }, "refseq": { "ac": "NP_001192646", "name": "5-hydroxytryptamine receptor 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192646" }, "gene_names": [ { "name": "HTR6", "type": "recommended", "evidence": [ { "id": "E1BE22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE22" } ] }, { "name": "HTR6", "type": "synonym", "evidence": [ { "id": "NP_001192646", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192646" } ] } ], "protein_names": [ { "name": "5-hydroxytryptamine receptor 6", "type": "recommended", "evidence": [ { "id": "E1BE22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE22/entry#names_and_taxonomy" } ] }, { "name": "5-hydroxytryptamine receptor 6", "type": "synonym", "evidence": [ { "id": "NP_001192646", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192646" } ] }, { "name": "Serotonin receptor 6", "type": "synonym", "evidence": [ { "id": "E1BE22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE22/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Also has a high affinity for tricyclic psychotropic drugs. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR6 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity. Is an activator of mTOR signaling.", "evidence": [ { "database": "UniProtKB", "id": "E1BE22", "url": "https://www.uniprot.org/uniprotkb/E1BE22#function" }, { "database": "UniProtKB", "id": "ARBA00059774", "url": "https://www.uniprot.org/uniprotkb/ARBA00059774#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BE22", "url": "https://www.uniprot.org/uniprotkb/E1BE22" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HTR6", "url": "https://www.uniprot.org/uniprotkb/E1BE22", "locus": { "chromosome": "2", "start_pos": 133022950, "end_pos": 133035378, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007996", "url": "https://www.ensembl.org/id/ENSBTAG00000007996" } ] } } ], "crossref": [ { "id": "E1BE22", "url": "https://alphafold.ebi.ac.uk/entry/E1BE22", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007996", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007996", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512167", "url": "https://www.ncbi.nlm.nih.gov/gene/512167", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512167", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512167", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KMGWHEL", "url": "https://omabrowser.org/oma/group/KMGWHEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BE22", "url": "https://www.orthodb.org/?gene=E1BE22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24247:SF236", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24247:SF236", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-390666", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-390666", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192646", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192646", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BE22", "url": "https://www.uniprot.org/uniprotkb/E1BE22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE22-1", "url": "https://www.uniprot.org/uniprotkb/E1BE22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPEQGPANYSTPDWGSGPPWAPGGSGWVAAALCVVIALTAAANSLLIALICAQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNVLYGRWVLARGLCLLWAAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPARALALVLGAWSLAALASFLPLLLGWHEPGRARAPAPGQCRLLASLPFVLVASGLTFFLPSGAICFTYSRILLAARKQAIQVASLTTGTAGQALETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISLGLFDTLTWLGYCNSTMNPIIYPLFMRDFKRALGRLLPCPRGPREQQPGLASPSVRTSHSGARPGLSLQHVLPLPLPPDSDSDSGSGSGGFSGPRLTAQLLLPGEATRDPPPPARATTTVNFFSIDRAEPELRPRPPGTPTN", "length": 440, "header": "tr|E1BE22-1|E1BE22_BOVIN Isoform 1 of 5-hydroxytryptamine receptor 6 OS=Bos taurus OX=9913 GN=HTR6 PE=3 SV=3 CANONICAL=E1BE22-1" }, "isoforms": [ { "isoform_ac": "E1BE22-1", "url": "https://www.uniprot.org/uniprotkb/E1BE22/entry#E1BE22-1", "sequence": { "sequence": "MVPEQGPANYSTPDWGSGPPWAPGGSGWVAAALCVVIALTAAANSLLIALICAQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNVLYGRWVLARGLCLLWAAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPARALALVLGAWSLAALASFLPLLLGWHEPGRARAPAPGQCRLLASLPFVLVASGLTFFLPSGAICFTYSRILLAARKQAIQVASLTTGTAGQALETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISLGLFDTLTWLGYCNSTMNPIIYPLFMRDFKRALGRLLPCPRGPREQQPGLASPSVRTSHSGARPGLSLQHVLPLPLPPDSDSDSGSGSGGFSGPRLTAQLLLPGEATRDPPPPARATTTVNFFSIDRAEPELRPRPPGTPTN", "length": 440, "header": "tr|E1BE22-1|E1BE22_BOVIN Isoform 1 of 5-hydroxytryptamine receptor 6 OS=Bos taurus OX=9913 GN=HTR6 PE=3 SV=3 CANONICAL=E1BE22-1" }, "locus": { "chromosome": "2", "start_pos": 133035378, "end_pos": 133022953, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010513.3", "url": "https://www.ensembl.org/id/ENSBTAT00000010513.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010513.3", "url": "https://www.ensembl.org/id/ENSBTAP00000010513.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512167", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512167", "resource": "KEGG Pathway" }, { "id": "R-BTA-390666", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-390666", "resource": "Reactome", "description": "Serotonin receptors" }, { "id": "R-BTA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZDZ2-1", "protein_name": "5-hydroxytryptamine receptor 6", "gene_name": "HTR6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"url": "https://omabrowser.org/oma/group/E1BE23/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9D2R4-1", "protein_name": "Transmembrane emp24 domain-containing protein 11", "gene_name": "Tmed11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQIQTILLCFSFSFSAAFYFHAGEREEKCIIEDIPSDTLITGTFKVQQWDIVRHDFLESAPGLGMFVTVTTYNDEVLLSKLYGAQGTFYFTSHSSGEHIICLESNSTQFVSFGGSKLRIHLDIRVGEHDLDAAIVQAKDKVNEVTFKLQHLIEQVEQILKEQDYQRDREENFRITSEDTNRNVLWWAFAQILIFISVGIFQMKHLKDFFIAKKLV", "length": 215 }, "evidence": [ { "id": "E1BE23", "url": "https://omabrowser.org/oma/group/E1BE23/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BE23", "url": 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May link mitochondria to the TRAK2-kinesin motor complex via its interaction with Miro and TRAK2. Mitochondrial distribution and dynamics is regulated through ARMCX3 protein degradation, which is promoted by PCK and negatively regulated by WNT1. 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"https://www.ensembl.org/id/ENSBTAG00000037996" } ] } } ], "crossref": [ { "id": "E1BE36", "url": "https://alphafold.ebi.ac.uk/entry/E1BE36", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000037996", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000037996", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "516747", "url": "https://www.ncbi.nlm.nih.gov/gene/516747", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516747", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516747", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DSKSIVW", "url": "https://omabrowser.org/oma/group/DSKSIVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BE36", "url": "https://www.orthodb.org/?gene=E1BE36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15712:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15712:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179382", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179382", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BE36", "url": "https://www.uniprot.org/uniprotkb/E1BE36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE36-1", "url": "https://www.uniprot.org/uniprotkb/E1BE36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGSGDVDDVGDCPGARYNDWSDDDDDNSENKGVVWYPPWARIGTEAGTRARARARARATRARRAVQKRASPNSDDTILSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKIYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEYQHMLANSISDFFRLFSAGNEETKFQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKENKEVILKLLVVFENINDNFKWEENESTQNQFSEGSLFFFLKEFQVCADKILGLESHQDFLVKVKVGKFVAKLAENMFPKSQE", "length": 379, "header": "tr|E1BE36-1|E1BE36_BOVIN Isoform 1 of Armadillo repeat-containing X-linked protein 3 OS=Bos taurus OX=9913 GN=ARMCX3 PE=3 SV=2 CANONICAL=E1BE36-1" }, "isoforms": [ { "isoform_ac": "E1BE36-1", "url": "https://www.uniprot.org/uniprotkb/E1BE36/entry#E1BE36-1", "sequence": { "sequence": "MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGSGDVDDVGDCPGARYNDWSDDDDDNSENKGVVWYPPWARIGTEAGTRARARARARATRARRAVQKRASPNSDDTILSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKIYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEYQHMLANSISDFFRLFSAGNEETKFQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKENKEVILKLLVVFENINDNFKWEENESTQNQFSEGSLFFFLKEFQVCADKILGLESHQDFLVKVKVGKFVAKLAENMFPKSQE", "length": 379, "header": "tr|E1BE36-1|E1BE36_BOVIN Isoform 1 of Armadillo repeat-containing X-linked protein 3 OS=Bos taurus OX=9913 GN=ARMCX3 PE=3 SV=2 CANONICAL=E1BE36-1" }, "locus": { "chromosome": "X", "start_pos": 50618506, "end_pos": 50617370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053008.4", "url": "https://www.ensembl.org/id/ENSBTAT00000053008.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051543.2", "url": "https://www.ensembl.org/id/ENSBTAP00000051543.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:516747", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516747", "resource": "KEGG Pathway" }, { "id": "R-BTA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BGW5-1", "protein_name": "Armadillo repeat-containing X-linked protein 3", "gene_name": "ARMCX3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGSGDVDDVGDCPGARYNDWSDDDDDNSENKGIVWYPPWARIGTEAGTRARARARARATRARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKIYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEYQHMLANSISDFFRLFSAGNEETKFQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKENKEVILKLLVIFENIIDNFKWEEDEPTQNQFSEGSLFFFLKEFQVCADKILGIESHQDFLVKVKVGKFMAKLAEHMFPKSQE", "length": 379 }, "evidence": [ { "id": "E1BE36", "url": "https://omabrowser.org/oma/group/E1BE36/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3ID11-1", "protein_name": "Armadillo repeat-containing X-linked protein 3", "gene_name": "Armcx3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGYARKVGWVTAGLVIGAGACYCIYRLARGRRQSKEKMAEGGSADVDDAGDCSGARYNDWSDDDDDSNDSKSIVWYPPWARIGTEAGTRARARARARATRARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKIYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEYQHILANSISDFFRLFLAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSALGSLFNKKENKEVILKLMIVLENINDNFKWEENEPAQNHFSGGSLFFFLKEFQVCADKVLGIESHHDFLVKVKVGKFAAKLTERMFPKSQE", "length": 379 }, "evidence": [ { "id": "E1BE36", "url": "https://omabrowser.org/oma/group/E1BE36/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5XID7-1", "protein_name": "Armadillo repeat-containing X-linked protein 3", "gene_name": "Armcx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGPGDVEDAGDCSGARYNDWSDDDDDSNESKSIVWYPPWARIGTEAGTRARARARARATRARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKIYMNQVCDDTVTSRLNSSVQLAGLRLLTNMTVTNEYQHILANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLGAHVPSSLGSLFNKKEYKEVILKLLSIFENINDNFKWEENEPAQNHFSEGSLFFFLKEFQVCADKVLGIESHHDFQVRVKVGKFVTKLTERMFPKSQE", "length": 379 }, "evidence": [ { "id": "E1BE36", "url": "https://omabrowser.org/oma/group/E1BE36/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BHS6-1", "protein_name": "Armadillo repeat-containing X-linked protein 3", "gene_name": "Armcx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGSGDVDDAGDCSGARYNDWSDDDDDSNESKSIVWYPPWARIGTEAGTRARARARARATRARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTVTSRLNSSVQLAGLRLLTNMTVTNEYQHILANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKEYKEVILKLLIIFENINDNFKWEENEPAQNHFSEGSLFFFLKEFQVCADKVLGIESRHDFQVRVKVGKFVAKLTERMFPKSQE", "length": 379 }, "evidence": [ { "id": "E1BE36", "url": "https://omabrowser.org/oma/group/E1BE36/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UH62-1", "protein_name": "Armadillo repeat-containing X-linked protein 3", "gene_name": "ARMCX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGSGDVDDAGDCSGARYNDWSDDDDDSNESKSIVWYPPWARIGTEAGTRARARARARATRARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEYQHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKENKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKVLGIESHHDFLVKVKVGKFMAKLAEHMFPKSQE", "length": 379 }, "evidence": [ { "id": "E1BE36", "url": "https://omabrowser.org/oma/group/E1BE36/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BE36", "url": "https://www.uniprot.org/uniprotkb/E1BE36" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BE36", "url": "https://www.uniprot.org/uniprotkb/E1BE36" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "E1BE36", "url": "https://www.uniprot.org/uniprotkb/E1BE36" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BE36", "url": "https://www.uniprot.org/uniprotkb/E1BE36" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "E1BE36", "url": "https://www.uniprot.org/uniprotkb/E1BE36" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "axonal transport of mitochondrion", "id": "GO:0019896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019896", "evidence": [ { "database": "UniProtKB", "id": "E1BE36", "url": "https://www.uniprot.org/uniprotkb/E1BE36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BE36-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 379, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BE36-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BE36" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BE36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE36" }, { "id": "PF04826", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Armadillo repeat-containing", "eco_id": "ECO_0000259", "start_pos": 118, "end_pos": 337, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 321, "end_pos": 323 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"uniprot_ac": "E1BE42", "uniprot_id": "E1BE42_BOVIN", "mass": { "chemical_mass": 16537.0, "monoisotopic_mass": 16537.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Large ribosomal subunit protein uL15", "type": "recommended", "evidence": [ { "id": "E1BE42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE42/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L27a", "type": "synonym", "evidence": [ { "id": "E1BE42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE42/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BE42", "url": "https://www.uniprot.org/uniprotkb/E1BE42" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377351" }, "gene_names": [ { "name": "OR2G1", "type": "recommended", "evidence": [ { "id": "E1BE74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE74" } ] }, { "name": "OR2G1", "type": "synonym", "evidence": [ { "id": "NP_001377351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377351" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BE74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE74/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2G3", "type": "synonym", "evidence": [ { "id": "NP_001377351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377351" } ] }, { "name": "olfactory receptor family 2 subfamily G member 1", "type": "synonym", "evidence": [ { "id": "NP_001377351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377351" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377351", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377351" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BE74", "url": "https://www.uniprot.org/uniprotkb/E1BE74#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BE74", "url": "https://www.uniprot.org/uniprotkb/E1BE74" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2G1", "url": "https://www.uniprot.org/uniprotkb/E1BE74", "locus": { "chromosome": "23", "start_pos": 29442553, "end_pos": 29443494, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000039534", "url": "https://www.ensembl.org/id/ENSBTAG00000039534" } ] } } ], "crossref": [ { "id": "E1BE74", "url": "https://alphafold.ebi.ac.uk/entry/E1BE74", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "785277", "url": "https://www.ncbi.nlm.nih.gov/gene/785277", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"database": "UniProtKB", "id": "E1BE74", "url": "https://www.uniprot.org/uniprotkb/E1BE74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "E1BE74", "url": "https://www.uniprot.org/uniprotkb/E1BE74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BE74-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"MEGSIHLSGLISRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDHSGDSLNSDEGDVSWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCSDCSEDGKEQYERLKLTWQQVVVLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPMYFRSGAQEFGEPGWWKLVHNRPPTLKPEGEKLSASALKVRASKPTLDPIITVEGLRKRASRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGFADRSSSSTPVKFISRGRRPDVILEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDEMEGDGVIDPGMEYVPPPAGTAASGTGLGGRKKVRAPEQIKQEVESEEEKPDRMDIDSEDTDSNTSLQMRAREKRKPVLEKDRKPKGPKFTPVSIYEEKLLLRRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDQVVNAALLLVDGIYGAKDGGVSRLPAGQATYRTTCQDFRILDRYQTALPSRKGFRHQSTKFLYRLVGSEDTAVDQSIVSPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHRGDPHWMPEPDAPLDYCYVRPNHIPTINSMCQEFFWPGVDLSECLQYPDFSVVVLYKKVIIAFGFMVPDVKYNEAYISFLFVHPDWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAFFLRLRR", "length": 781, "header": "tr|E1BE91-1|E1BE91_BOVIN Isoform 1 of Cysteine-rich protein 2-binding protein OS=Bos taurus OX=9913 GN=KAT14 PE=4 SV=4 CANONICAL=E1BE91-1" }, "isoforms": [ { "isoform_ac": "E1BE91-1", "url": "https://www.uniprot.org/uniprotkb/E1BE91/entry#E1BE91-1", "sequence": { "sequence": "MEGSIHLSGLISRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDHSGDSLNSDEGDVSWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCSDCSEDGKEQYERLKLTWQQVVVLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPMYFRSGAQEFGEPGWWKLVHNRPPTLKPEGEKLSASALKVRASKPTLDPIITVEGLRKRASRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGFADRSSSSTPVKFISRGRRPDVILEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDEMEGDGVIDPGMEYVPPPAGTAASGTGLGGRKKVRAPEQIKQEVESEEEKPDRMDIDSEDTDSNTSLQMRAREKRKPVLEKDRKPKGPKFTPVSIYEEKLLLRRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDQVVNAALLLVDGIYGAKDGGVSRLPAGQATYRTTCQDFRILDRYQTALPSRKGFRHQSTKFLYRLVGSEDTAVDQSIVSPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHRGDPHWMPEPDAPLDYCYVRPNHIPTINSMCQEFFWPGVDLSECLQYPDFSVVVLYKKVIIAFGFMVPDVKYNEAYISFLFVHPDWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAFFLRLRR", "length": 781, "header": "tr|E1BE91-1|E1BE91_BOVIN Isoform 1 of Cysteine-rich protein 2-binding protein OS=Bos taurus OX=9913 GN=KAT14 PE=4 SV=4 CANONICAL=E1BE91-1" }, "locus": { "chromosome": "13", "start_pos": 38359154, "end_pos": 38334108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025259.8", "url": "https://www.ensembl.org/id/ENSBTAT00000025259.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025259.7", "url": "https://www.ensembl.org/id/ENSBTAP00000025259.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 338, "start_aa": "Thr", "end_pos": 338, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr338", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 345, "start_aa": "Thr", "end_pos": 345, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr345", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:541019", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541019", "resource": "KEGG Pathway" }, { "id": "R-BTA-9772755", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9772755", "resource": "Reactome", "description": "Formation of WDR5-containing histone-modifying complexes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZEF4-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "KAT14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MANNVHMSGLLSRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDASWMEEMSYYCEKCQKWIPASQLREQLSYLKGDNFFRFTCSDCSEDGKEQFERLRLTWQQVVMLAMYNLSLEGTGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPLYFRSGAQEFGEPGWWKLVHNKPPTMKPEGEKLSASALKAKAASKPPLDPIITVEGLRKRVSRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGFLDRSTSSTPVKFSSRGRRPDIVLEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDEEMEGDGVIDPGIEYVPTPSGTAGAGTMIASRKKVKTAEQIKQEVESEEEKTERMEGDSEDPEESNTSLQLRGRDKRKPQLEKDAKPRAPKHTSVSIYEEKLLLKRLEACPNALSMTPEARRLRRKLIVRQAKRERGLPLFDLDQVVNAALLLVDGIYGAKEGVSRSPVGQATYRTTSQDFRILDRYQTVLPAMKGYRQQTTKFLYRLVGSEDLLPDHSIVSPYTSRVLKPYIRRDYETKPPKLRLLAEIWAYPHRNDLNWKAEPEAPIDYCYVRPNHIPTINSMCHEFFWPGIDLSECLQYPDFSVVVLYKKVIIAFGFMVPDVKYNEAYISFLFVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYILDFYDKYYPLDSKECKHAFFLRLRR", "length": 781 }, "evidence": [ { "id": "E1BE91", "url": "https://omabrowser.org/oma/group/E1BE91/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZSX8-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "Kat14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIHLSGLLSRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDISWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCADCSADGKEQSERLKLTWQQVVMLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPVYFRSGAQEFGEPGWWKLVHNRPPTMRPEGEKLSASTLKVKASKPTLDPIITVEGLRKRASRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGLLDRSTSSTPVKFISRGRRPDMILEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDELEGDGVIDPGMEYIPPPAGSASGLMGSRKKVRAAEQIKQEVDSEEEKPDRMDGDSEDTDSNTSLHTRAREKRKPPLEKDTKPKGPRYTPVSIYEEKLLLKRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDEVVNAALLLVDGIYGAKDGGASRLPAGQATYRTTCQDFRILDRYQTALPARKGFRHQTTRFLYRLVGSEDLAVDQSIVSPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHKSDPHWTPEPDAPLDYCYVRPNHIPTINSMCQEFFWPGIDLSECLQYPDFSVVVLYKKVIVAFGFMVPDVKYNEAYISFLLVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAFFLRLRR", "length": 779 }, "evidence": [ { "id": "E1BE91", "url": "https://omabrowser.org/oma/group/E1BE91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SBH7-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "KAT14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METNIHLGSLISRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDMSWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCSDCSEDGKEQYERLKLTWQQVVMLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPMYFRSGAQEFGEPGWWKLVHSRPPTLKPEGEKLATSALKVKASKPTLDPIITVEGLRKRASRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGFLDRSTSSTPVKFVSRGRRPDMILEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDELEGDGVIDPGMEYVPPPACSSASGTGVGGRKKVRAPEQIKQEVESEEEKPDRMDIDSEDTDSNTSLQTRAREKRKQALEKDRKPKGPKFTPVSIYEEKLLLKRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDQVVNAALLLVDGIYGAKDGGVSRLPAGQATYRTTCQDFRILDRYQTALPSRKGFRHQTSKFLYRLVGSEDMAVDQSIVSPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHRSDPHWTPEPDAPLDYCYVRPNHIPTINSMCQEFFWPGVDLSECLQYPDFSVVVLYKKVIIAFGFMVPDVKYNEAYISFLFVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAFFLRLRR", "length": 781 }, "evidence": [ { "id": "E1BE91", "url": "https://omabrowser.org/oma/group/E1BE91/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1LXR5-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "kat14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSGDQRGLTVQDEETMCTSASEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDIGEDGEGSWNEDMSFYCDKCHKWIPAVQLRGEQPSYLKGDNFFKFICSDCAEDGKESFERMRLTWQQVVMLAMYNLSLEGTGRQGYFRWKEDICAFISRHWTFLLGSRKKTSTWWSTVAGCLSVGSPTFFRSGAQEFGEPGWWKLVQNRPPTLRPEGDKSSAASVKAKAVSKPSLDPIITVEGLRKRGSRNPVENAMQLKEKRSRTQEAKEIRRAQKEAAGFLDRSASSTPVKLGNRARRPEPYLEKGEVIDFSSLSSSDRTPLTSPSPSPSPDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDEELDAEGVIDPGMEYIPPPSMPLATGTIMVRKKLRPAELIKQELESEDEERGRDVEEDEGQDDGRRGRVLERRKGLQDKGEGCVSLPAPRHTFISLYEERMLLHKLEACPQALAVTPQAKRLHRKLLVRQAKRERGLPLLDVDQAVSATLSLVGGVYGAQGGLARHRTSGEEKYRTTSQDLRILDRFQSTVSVRKGFYQHTVSFWHRLMGSDACVDQTIKSPYTSRVLKPFIRRDYESRPLKLRLLSEIRAHHHRNDPNWVAEPDAPIDYCYVRPNHIPSVNSMCQDIFWPGIDLSECLQYPDFSVVVLYKKVVIGFGFMVPDVKYNEAYISFLLVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNSAMLLYQKFGFKTEEYILDFYDKYYPVDSKECRHAFLLRLRR", "length": 782 }, "evidence": [ { "id": "E1BE91", "url": "https://omabrowser.org/oma/group/E1BE91/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CID0-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "Kat14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSIHLSGLLSRHDDDATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDVSWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCCDCSADGKEQYERLKLTWQQVVMLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPVYFRSGAQEFGEPGWWKLVHNRPPTMRPEGEKLAASTLKVKASKPTLDPIITVEGLRKRASRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGLLDRSTSSTPVKFISRGRRPDLILEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDELEGDGVIDPGMEYIPPPAGSASGLLGSRKKVRAPEQIKQEVDSEEEKPDRMDGDSEDTDSNISLHTRAREKRKPPLEKDMKPKGPRYTPVSIYEEKLLLKRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDEVVNAALLLVDGIYGAKDGGASRLAAGQATYRTTCQDFRILDRYQTALPARKGFRHQTTRFLYRLVGSEDLAVDQSIISPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHRSDPHWTPGPDAPLDYCYVRPNHIPTINSMCQEFFWPGIDLSECLQYPDFSVVVLYKKVIVAFGFMVPDVKYNEAYISFLLVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAFFLRLRR", "length": 779 }, "evidence": [ { "id": "E1BE91", "url": "https://omabrowser.org/oma/group/E1BE91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8E8-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "KAT14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSSIHLSSLISRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDVSWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCSDCSADGKEQYERLKLTWQQVVMLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPMYFRSGAQEFGEPGWWKLVHNKPPTMKPEGEKLSASTLKIKAASKPTLDPIITVEGLRKRASRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGFLDRSTSSTPVKFISRGRRPDVILEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDEMEGDGVIDPGMEYVPPPAGSVASGPVVGVRKKVRGPEQIKQEVESEEEKPDRMDIDSEDTDSNTSLQTRAREKRKPQLEKDTKPKEPRYTPVSIYEEKLLLKRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDQVVNAALLLVDGIYGAKEGGISRLPAGQATYRTTCQDFRILDRYQTSLPSRKGFRHQTTKFLYRLVGSEDMAVDQSIVSPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHRSDPHWTPEPDAPLDYCYVRPNHIPTINSMCQEFFWPGIDLSECLQYPDFSVVVLYKKVIIAFGFMVPDVKYNEAYISFLFVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAFFLRLRR", "length": 782 }, "evidence": [ { "id": "E1BE91", "url": "https://omabrowser.org/oma/group/E1BE91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VJ73-1", "protein_name": "2.3.1.-", "gene_name": "Atac2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNRPSNWDDPQGPCRYCESPVEDDNYLECQECRRMVHIKCLPHACTPGDLLGDVFFEFTCVKCVLDKAKESVIPSDLEPIKEVIVRQRIPWLLVLTLTLYNLSIKQKGLGHHGFFHWRTHIISFVDKNWNYIFGPNVRRRKQWTGSVSGALSHNSPEYFQSGLDVFQENGWWKLAKPFQTPRSVLKEYEKKQQLRLQMRIEKRLPAADETSCSSEISVADHAQDNPPLIKAEAEKPSSTEGCARTIPYMGRLPKIQTQPSPLSQETLPGPPILQENIAPPSQKEEEPQNQPMSMVQAGLMDFLAESLESDDFTMFGNLPGIMPPPLIGAGKNDFFMTEPLLHAPLNNEGLFDMDTNFAIPNTADETKPISTEEPAAESSEEQKEGEVEDEKPEEDESPDYQPRIVQVTNYQAQEANESIKEEPLEEIMQDDDVTTNSKSSILEPCKPSGFVRQPRRNWPWLQEAQDPDDMAIPSENLKLINAYEEQKLYQRLDRIFALEHQCHISIPAYVRRLYRKLSLRKWKRDHNRHIFNLDEHIDPLGRARLKMLGHQKAEILDRYQLLAHSRQDARSSFHARLAGCTQYELFESPYSQRVLHPFIFRSETMAPPWLKLMCELQHRVNGSHPTRSTIDFCFVRPQHIPAVNALLQSTFWPNIDVSECLSYPDYSVVALYKKLVIGCGFLVPDVGYNEAYISFMAVRPCWQRSGIASFMLYHLIQTCMSKDITLHVSATNAAVMLYQKFGFKMEEIILDFYDKYLPLDSKQSRNAFFLRLQR", "length": 774 }, "evidence": [ { "id": "E1BE91", "url": "https://omabrowser.org/oma/group/E1BE91/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BE91", "url": "https://www.uniprot.org/uniprotkb/E1BE91" } ], "pmid": "" }, { "name": "ATAC complex", "id": "GO:0140672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140672", "evidence": [ { "database": "UniProtKB", "id": "E1BE91", "url": "https://www.uniprot.org/uniprotkb/E1BE91" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histone acetyltransferase activity", "id": "GO:0004402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004402", "evidence": [ { "database": "UniProtKB", "id": "E1BE91", "url": "https://www.uniprot.org/uniprotkb/E1BE91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "E1BE91", "url": "https://www.uniprot.org/uniprotkb/E1BE91" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "E1BE91", "url": "https://www.uniprot.org/uniprotkb/E1BE91" } ], "pmid": "" }, { "name": "regulation of cell division", "id": "GO:0051302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051302", "evidence": [ { "database": "UniProtKB", "id": "E1BE91", "url": "https://www.uniprot.org/uniprotkb/E1BE91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BE91-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 781, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BE91-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BE91" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BE91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE91" }, { "id": "PS51186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 637, "end_pos": 781, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 338, 345 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 433, "end_pos": 435 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", 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{ "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 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of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.", "evidence": [ { "database": "UniProtKB", "id": "E1BE99", "url": "https://www.uniprot.org/uniprotkb/E1BE99#function" }, { "database": "UniProtKB", "id": "ARBA00003263", "url": "https://www.uniprot.org/uniprotkb/ARBA00003263#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BE99", "url": "https://www.uniprot.org/uniprotkb/E1BE99" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HOXD12", "url": "https://www.uniprot.org/uniprotkb/E1BE99", "locus": { "chromosome": "2", "start_pos": 20812814, "end_pos": 20813774, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004314", "url": "https://www.ensembl.org/id/ENSBTAG00000004314" } ] } } ], "crossref": [ { "id": "E1BE99", "url": "https://alphafold.ebi.ac.uk/entry/E1BE99", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004314", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004314", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "520423", "url": "https://www.ncbi.nlm.nih.gov/gene/520423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:520423", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YYAHDTS", "url": "https://omabrowser.org/oma/group/YYAHDTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BE99", "url": "https://www.orthodb.org/?gene=E1BE99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46440", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46440", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46440:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46440:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192800", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192800", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BE99", "url": "https://www.uniprot.org/uniprotkb/E1BE99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE99-1", "url": "https://www.uniprot.org/uniprotkb/E1BE99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWATTPASCAPAQPAGATAFGSFPQPYLAGSGPLGLQPLGAKDGSEEQAKYYTPDAAAEPEERGRARPPFIPESSLAPAAAALKAAKYDYTGMGRVAPGSSTLLEGTPCSAGFKDDAKGPLNLNMTMQAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLLNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALALY", "length": 269, "header": "tr|E1BE99-1|E1BE99_BOVIN Isoform 1 of Homeobox D12 OS=Bos taurus OX=9913 GN=HOXD12 PE=3 SV=3 CANONICAL=E1BE99-1" }, "isoforms": [ { "isoform_ac": "E1BE99-1", "url": "https://www.uniprot.org/uniprotkb/E1BE99/entry#E1BE99-1", "sequence": { "sequence": "MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWATTPASCAPAQPAGATAFGSFPQPYLAGSGPLGLQPLGAKDGSEEQAKYYTPDAAAEPEERGRARPPFIPESSLAPAAAALKAAKYDYTGMGRVAPGSSTLLEGTPCSAGFKDDAKGPLNLNMTMQAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLLNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALALY", "length": 269, "header": "tr|E1BE99-1|E1BE99_BOVIN Isoform 1 of Homeobox D12 OS=Bos taurus OX=9913 GN=HOXD12 PE=3 SV=3 CANONICAL=E1BE99-1" }, "locus": { "chromosome": "2", "start_pos": 20813774, "end_pos": 20812817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005652.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005652.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005652.6", "url": "https://www.ensembl.org/id/ENSBTAP00000005652.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:520423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520423", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSN2-1", "protein_name": "Homeo box D12", "gene_name": "Hoxd12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGSQLAALPPISYPRSALPWAATPASCTPAQPTTASAFGGFSQPYLTGSGPIGLQSPGTKDGPEDQVKFYTPDAATASEERSRTRPPFAPESSLVHSALKGTKYDFAGVGRAAPGSVTLLQGAPCASNFKEDTKGPLNLNMAVQVAGVASCLRSSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVQREQALALY", "length": 268 }, "evidence": [ { "id": "E1BE99", "url": "https://omabrowser.org/oma/group/E1BE99/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RZG4-1", "protein_name": "Homeobox D12", "gene_name": "HOXD12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWATTPASCAPAQTAGATAFGSFPQPYLAGSGPLGLQPLGAKDGSEEQAKFYTPDAAAGPEERGRVRPPFIPESSLAPAAAALKAAKYDYAGVGRVAPGSSALLEGTPCSAGFKDDVKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLLNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALSLY", "length": 270 }, "evidence": [ { "id": "E1BE99", "url": "https://omabrowser.org/oma/group/E1BE99/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H1U8-1", "protein_name": "Homeobox protein Hox-D12", "gene_name": "Hoxd12", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCERSLYRAGYVGSILNLQSPDSFYFSNLRPNGSQLAALPPISYPRGALPWAATPASCTPAQPATASAFGGFSQPYLTGSGPLGLQSPSAKDGPEEQVKFYTADAATGSEERSRTRPPFAPESSLAHSALKGTKYDYAGVGRAVPSSATLLQGAPCTSSFKEDTKGPLNLNMTVQVAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVQREQALALY", "length": 268 }, "evidence": [ { "id": "E1BE99", "url": "https://omabrowser.org/oma/group/E1BE99/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P23812-1", "protein_name": "Homeobox protein Hox-D12", "gene_name": "Hoxd12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCERSLYRAGYVGSLLNLQSPDSFYFSNLRANGSQLAALPPISYPRSALPWATTPASCTPAQPATASAFGGFSQPYLTGSGPIGLQSPGAKDGPEDQVKFYTPDAPTASEERSRTRPPFAPESSLVHSALKGTKYDYAGVGRTAPGSATLLQGAPCASSFKEDTKGPLNLNMAVQVAGVASCLRSSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVQREQALALY", "length": 268 }, "evidence": [ { "id": "E1BE99", "url": "https://omabrowser.org/oma/group/E1BE99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P24343-1", "protein_name": "Homeobox protein Hox-D12", "gene_name": "HOXD12", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCDRSLYRSGYVGSLLNLQSPDSFYFPNLRANGSQLAALPTISYPRSSIPWTCPSPCAAQPQGHAFGGAAQPYLPGSVPISISSNSNKECLEENSKYYAHDASSKQEERCRQRQSFANDPTITHAANLKPAKYDHSSLPRSLHGSAALFEVNSCTSSLKEDIKNSVNLNLTVQPAAVQSCLRPSVQDGLPWCPTQGRSRKKRKPYTKQQIAELENEFLLNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVMREQALSMY", "length": 266 }, "evidence": [ { "id": "E1BE99", "url": "https://omabrowser.org/oma/group/E1BE99/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P35452-1", "protein_name": "Homeobox protein Hox-D12", "gene_name": "HOXD12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALALY", "length": 270 }, "evidence": [ { "id": "E1BE99", "url": "https://omabrowser.org/oma/group/E1BE99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q90471-1", "protein_name": "Homeobox protein Hox-D12a", "gene_name": "hoxd12a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCEHNLLSSGYVAPLLNFHSPDSLYLQNLRGNGVHLSGLPQMSYSRREVCSLPWSSSNSCTAPAQSRAYSGYSQPFFSNSAAVSASLNTHKKGSLEESGRYYFQDVSHKSEEPGRPNAAYASEQSSASNGLSNLERRQLNAVAPNELSCIEQPESDASKQSVSSIAPFQPSLSAQNIRPAFTDGLPWCPSQVRSRKKRKPYTKPQLTELENEFMMNEFINRQKRKELSDRLELSDQQVKIWFQNRRMKKKRLMMREHTFTIY", "length": 262 }, "evidence": [ { "id": "E1BE99", "url": "https://omabrowser.org/oma/group/E1BE99/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BE99", "url": "https://www.uniprot.org/uniprotkb/E1BE99" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "E1BE99", "url": "https://www.uniprot.org/uniprotkb/E1BE99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BE99", "url": "https://www.uniprot.org/uniprotkb/E1BE99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BE99", "url": "https://www.uniprot.org/uniprotkb/E1BE99" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "E1BE99", "url": "https://www.uniprot.org/uniprotkb/E1BE99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BE99-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 269, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BE99-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BE99" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BE99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE99" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 259, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 239, "end_pos": 241 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEA2-1", "uniprot_ac": "E1BEA2", "uniprot_id": "E1BEA2_BOVIN", "mass": { "chemical_mass": 55932.0, "monoisotopic_mass": 55932.0 }, "refseq": { "ac": "NP_001422046", "name": "enhancer of mRNA-decapping protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422046" }, "gene_names": [ { "name": "EDC3", "type": "recommended", "evidence": [ { "id": "E1BEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEA2" } ] }, { "name": "EDC3", "type": "synonym", "evidence": [ { "id": "NP_001422046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422046" } ] }, { "name": "LSM16", "type": "synonym", "evidence": [ { "id": "NP_001422046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422046" } ] } ], "protein_names": [ { "name": "Enhancer of mRNA-decapping protein 3", "type": "recommended", "evidence": [ { "id": "E1BEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEA2/entry#names_and_taxonomy" } ] }, { "name": "YjeF domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "E1BEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEA2/entry#names_and_taxonomy" } ] }, { "name": "enhancer of mRNA decapping 3 homolog", "type": "synonym", "evidence": [ { "id": "NP_001422046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422046" } ] }, { "name": "enhancer of mRNA-decapping protein 3", "type": "synonym", "evidence": [ { "id": "NP_001422046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422046" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEA2", "url": "https://www.uniprot.org/uniprotkb/E1BEA2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EDC3", "url": "https://www.uniprot.org/uniprotkb/E1BEA2", "locus": { "chromosome": "21", "start_pos": 34045829, "end_pos": 33991648, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007308", "url": "https://www.ensembl.org/id/ENSBTAG00000007308" } ] } } ], "crossref": [ { "id": "E1BEA2", "url": "https://alphafold.ebi.ac.uk/entry/E1BEA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007308", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007308", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01737", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01737", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "517979", "url": "https://www.ncbi.nlm.nih.gov/gene/517979", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NHQWPKI", "url": "https://omabrowser.org/oma/group/NHQWPKI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEA2", "url": "https://www.orthodb.org/?gene=E1BEA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13612", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13612", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13612:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13612:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-430039", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-430039", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001422046", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422046", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BEA2", "url": "https://www.uniprot.org/uniprotkb/E1BEA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEA2-1", "url": "https://www.uniprot.org/uniprotkb/E1BEA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGETQHFGDLHQTELGSSGVGCQVGINQNGTGKLVKKPASSSSVPQNIPKRTDVKSQDVAISPQQQQCSKSYVDRHTESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGTRSRGIPNERPTRYRHDENILESEPIVYRRITVPHNVSKEFCTDSGLVVPSISYELHKKLLAVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPAVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENAFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEGEQGIDAKWSLALGLPLPLGEHAGRVYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA", "length": 508, "header": "tr|E1BEA2-1|E1BEA2_BOVIN Isoform 1 of Enhancer of mRNA-decapping protein 3 OS=Bos taurus OX=9913 GN=EDC3 PE=3 SV=3 CANONICAL=E1BEA2-1" }, "isoforms": [ { "isoform_ac": "E1BEA2-1", "url": "https://www.uniprot.org/uniprotkb/E1BEA2/entry#E1BEA2-1", "sequence": { "sequence": "MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGETQHFGDLHQTELGSSGVGCQVGINQNGTGKLVKKPASSSSVPQNIPKRTDVKSQDVAISPQQQQCSKSYVDRHTESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGTRSRGIPNERPTRYRHDENILESEPIVYRRITVPHNVSKEFCTDSGLVVPSISYELHKKLLAVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPAVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENAFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEGEQGIDAKWSLALGLPLPLGEHAGRVYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA", "length": 508, "header": "tr|E1BEA2-1|E1BEA2_BOVIN Isoform 1 of Enhancer of mRNA-decapping protein 3 OS=Bos taurus OX=9913 GN=EDC3 PE=3 SV=3 CANONICAL=E1BEA2-1" }, "locus": { "chromosome": "21", "start_pos": 34044825, "end_pos": 34012879, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009613.8", "url": "https://www.ensembl.org/id/ENSBTAT00000009613.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009613.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009613.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-430039", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-430039", "resource": "Reactome", "description": "mRNA decay by 5' to 3' exoribonuclease" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TMS6-1", "protein_name": "Enhancer of mRNA-decapping protein 3", "gene_name": "EDC3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGENQHFGDLHQAELGPSGVGCQVGIGQNGMGKLVKKPASSSSAPQNIPKRTDVKSQDVAVSPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGSRSRGIPNERPTRYRHDENILESEPIVYRRITVPHNVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNIHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFMKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENAFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRVYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA", "length": 508 }, "evidence": [ { "id": "E1BEA2", "url": "https://omabrowser.org/oma/group/E1BEA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1M7Z1-1", "protein_name": "Enhancer of mRNA-decapping protein 3", "gene_name": "Edc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EAMDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDNQQFGDLHQTELGPSGVGYQMSINQNGTGKVVKKPASSSSAPQSIPKRTDMKSQDVAISPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGSRSRGVPNERPARYRHDENILESEPIVYRRITVPHSVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLRDLPTSPVDLVINCLDCPENAFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRVYLCDIGIPQQVFQEVGIDYHSPFGCKFVIPLHSA", "length": 508 }, "evidence": [ { "id": "E1BEA2", "url": "https://omabrowser.org/oma/group/E1BEA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q502M5-1", "protein_name": "Enhancer of mRNA-decapping protein 3", "gene_name": "edc3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALDWVGNLVSIHCGPTLGVYQGEISSVDQTSQTISLRNPFHNGVKCTVPEVTFSAMDIKDLKILEISKNSIEVSKQNGPESSSTTLMPHVGRKDKGGGGGGGGAPANSAPVMVPNKAEPRLQEGGVSPVPHYSKSYGERHIDMAVQGKGFRRRHNSWSSSCRGPNQATPKKNGLKNGGHMKNKDDECFGDGMDDVLDEDFDFEGNLALFDKAAVLSQIESSERRGNGARSRGTPGEQTPSRYRHDENILEAKPVVYRQITVPQNGSKEYSTDSGLVVPSISFELHKRLLAAAESHGLSLERRLEMTGVCASQMALTLLGGPNRLTPKNVHQRPTVALLCGPHVQGAQGISCGRHLANHEVEVVLFLPNFVKMLEAITSELALFGKTGGRLVSNVKDLPETPVDLVINCLDSHENGFLRDQPWYKAAADWANQNRAPVLSIDPPVSGQAHAVEAKWSLSLGLPLPLSEGAGRVYPCDIGIPRQVFQEVGIKYHSPFGCKFVIPLHSE", "length": 507 }, "evidence": [ { "id": "E1BEA2", "url": "https://omabrowser.org/oma/group/E1BEA2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K2D3-1", "protein_name": "Enhancer of mRNA-decapping protein 3", "gene_name": "Edc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDNQQVGDLHQTELGPSGVGYQMSISQNGTGKVVKKPASSSSAPQSIPKRTDVKSQDVAISPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEELPDTDFDFEGNLALFDKAAVFEEIDTYERRSGSRSRGVPNERPARYRHDENILESEPIVYRRITVPHSVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLRDLPASPVDLVINCLDCPENAFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRVYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA", "length": 508 }, "evidence": [ { "id": "E1BEA2", "url": "https://omabrowser.org/oma/group/E1BEA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96F86-1", "protein_name": "Enhancer of mRNA-decapping protein 3", "gene_name": "EDC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDNQHFGDLHQTELGPSGAGCQVGINQNGTGKFVKKPASSSSAPQNIPKRTDVKSQDVAVSPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGTRSRGIPNERPTRYRHDENILESEPIVYRRIIVPHNVSKEFCTDSGLVVPSISYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENVFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRIYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA", "length": 508 }, "evidence": [ { "id": "E1BEA2", "url": "https://omabrowser.org/oma/group/E1BEA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1BEA2", "url": "https://www.uniprot.org/uniprotkb/E1BEA2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BEA2", "url": "https://www.uniprot.org/uniprotkb/E1BEA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "E1BEA2", "url": "https://www.uniprot.org/uniprotkb/E1BEA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "P-body assembly", "id": "GO:0033962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033962", "evidence": [ { "database": "UniProtKB", "id": "E1BEA2", "url": "https://www.uniprot.org/uniprotkb/E1BEA2" } ], "pmid": "" }, { "name": "deadenylation-independent decapping of nuclear-transcribed mRNA", "id": "GO:0031087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031087", "evidence": [ { "database": "UniProtKB", "id": "E1BEA2", "url": "https://www.uniprot.org/uniprotkb/E1BEA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEA2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 508, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEA2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEA2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEA5-1", "uniprot_ac": "E1BEA5", "uniprot_id": "E1BEA5_BOVIN", "mass": { "chemical_mass": 55640.0, "monoisotopic_mass": 55640.0 }, "refseq": { "ac": "XP_005215489", "name": "zinc finger protein PLAG1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215489" }, "gene_names": [ { "name": "PLAG1", "type": "recommended", "evidence": [ { "id": "E1BEA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ] }, { "name": "PLAG1", "type": "synonym", "evidence": [ { "id": "XP_005215489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215489" } ] } ], "protein_names": [ { "name": "Zinc finger protein PLAG1", "type": "recommended", "evidence": [ { "id": "E1BEA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEA5/entry#names_and_taxonomy" } ] }, { "name": "Pleiomorphic adenoma gene 1 protein", "type": "synonym", "evidence": [ { "id": "E1BEA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEA5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein PLAG1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005215489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215489" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PLAG1", "url": "https://www.uniprot.org/uniprotkb/E1BEA5", "locus": { "chromosome": "14", "start_pos": 23330511, "end_pos": 23335698, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004022", "url": "https://www.ensembl.org/id/ENSBTAG00000004022" } ] } } ], "crossref": [ { "id": "E1BEA5", "url": "https://alphafold.ebi.ac.uk/entry/E1BEA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004022", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004022", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539210", "url": "https://www.ncbi.nlm.nih.gov/gene/539210", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539210", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539210", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEAFACQ", "url": "https://omabrowser.org/oma/group/KEAFACQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEA5", "url": "https://www.orthodb.org/?gene=E1BEA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005215489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215489", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEA5-1", "url": "https://www.uniprot.org/uniprotkb/E1BEA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKSYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSAGGVKEKKHPCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFPSTLQLNLYNTPFQSVQSSGSAHQMITTLPLGMTCPIDMDAVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYLMELQGGVPSSSQDSPASSSKLGLEPQLGSLEDSTGDLSLSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPISVGSLGMSYSQEEAHSSVSQLPPQSQDLPDPASTIGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ", "length": 499, "header": "tr|E1BEA5-1|E1BEA5_BOVIN Isoform 1 of Zinc finger protein PLAG1 OS=Bos taurus OX=9913 GN=PLAG1 PE=3 SV=1 CANONICAL=E1BEA5-1" }, "isoforms": [ { "isoform_ac": "E1BEA5-1", "url": "https://www.uniprot.org/uniprotkb/E1BEA5/entry#E1BEA5-1", "sequence": { "sequence": "MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKSYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSAGGVKEKKHPCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFPSTLQLNLYNTPFQSVQSSGSAHQMITTLPLGMTCPIDMDAVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYLMELQGGVPSSSQDSPASSSKLGLEPQLGSLEDSTGDLSLSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPISVGSLGMSYSQEEAHSSVSQLPPQSQDLPDPASTIGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ", "length": 499, "header": "tr|E1BEA5-1|E1BEA5_BOVIN Isoform 1 of Zinc finger protein PLAG1 OS=Bos taurus OX=9913 GN=PLAG1 PE=3 SV=1 CANONICAL=E1BEA5-1" }, "locus": { "chromosome": "14", "start_pos": 23332546, "end_pos": 23330544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005251.5", "url": "https://www.ensembl.org/id/ENSBTAT00000005251.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005251.3", "url": "https://www.ensembl.org/id/ENSBTAP00000005251.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539210", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539210", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q58NQ5-1", "protein_name": "Zinc finger protein PLAG1", "gene_name": "PLAG1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCTQQDCTKAFVSKYKLLRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHNPNKEAFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKTHAGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPMDLLDPFTCNVSVPIKDELLPVMSLPSSELTSKPFTNTLQLNLYNTQIQSMQSSASAHQMVATSLPLGMPCPIDMESVHPSHQLSLKYPLSSTSYAVSMPEKEQPLKGEIESYLMELQSGMPSSSQDSQASSSKLGLDPQVGPLDDGSGEVSLSKGSVPISEPLNTPSLDFSQLFNFIPVNGPPYNPSVSVGNLGMSYTQEEAHSSMTQLPPQTQDPQDPSNSIGLGSLHSLSAAFTSSLSTTTTLPRFHQAFQ", "length": 501 }, "evidence": [ { "id": "E1BEA5", "url": "https://omabrowser.org/oma/group/E1BEA5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5U2T6-1", "protein_name": "Zinc finger protein PLAG1", "gene_name": "Plag1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATVIPGDLSEVRDTQKAPSGKRKRGESKPRKNFPCQLCDKAFNSVEKLKVHSFSHTGERPYKCTHQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKSYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGVKEKKHQCEHCERRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNMSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQSSGSTHQMITTLPLGMTCPIDMDTVHPSHHLAFKCPFSSTSYAISIPEKEQPLKGEIESYLMELQGGAPSSSQDSQASSSKLGLEPQSGSPDDGAGDLSLSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQDEAHSSVSQLPTQTQDLQDPANTVGLGSLHSLSAAFTSSLSSSTTLPRFHQAFQ", "length": 499 }, "evidence": [ { "id": "E1BEA5", "url": "https://omabrowser.org/oma/group/E1BEA5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DJT9-1", "protein_name": "Zinc finger protein PLAG1", "gene_name": "PLAG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ", "length": 500 }, "evidence": [ { "id": "E1BEA5", "url": "https://omabrowser.org/oma/group/E1BEA5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYE0-1", "protein_name": "Zinc finger protein PLAG1", "gene_name": "Plag1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVIPGDLSEVRDTQKAPSGKRKRGESKPRKNFPCQLCDKAFNSVEKLKVHSFSHTGERPYKCTHQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKSYNTKLGFKRHLALHAATSGDLTCKVCLQNFESTGVLLEHLKSHAGKSSGGVKEKKHQCEHCERRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNMSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQSSGSAHQMITTLPLGMTCPIDMDAVHPSHHLAFKCPFSSTSYAISIPEKEQPLKGEIESYLMELQGGAPSSSQDSPASSSKLGLEPQSGSPDDGAGDLSLSKSSISISDPLSTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPTQTQDLQDPANTVGLSSLHSLSAAFTSSLSSSTTLPRFHQAFQ", "length": 499 }, "evidence": [ { "id": "E1BEA5", "url": "https://omabrowser.org/oma/group/E1BEA5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of glial cell proliferation", "id": "GO:0060252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060252", "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BEA5", "url": "https://www.uniprot.org/uniprotkb/E1BEA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": 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"Protein Classification" ] }, { "id": "PF00276", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00276", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03939", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03939", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BED6", "url": "https://www.uniprot.org/uniprotkb/E1BED6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BED6-1", "url": "https://www.uniprot.org/uniprotkb/E1BED6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "APKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHDAIIKFPLTTESAMKKIEDNNTLVCIVDVKANKHQIKQAVKKLYDTDVAKVNTLIRPDGEKKVYVRLAPDYDALDVANKIGII", "length": 155, "header": "tr|E1BED6-1|E1BED6_BOVIN Isoform 1 of Large ribosomal subunit protein uL23 OS=Bos taurus OX=9913 GN=LOC107132395 PE=3 SV=3 CANONICAL=E1BED6-1" }, "isoforms": [ { "isoform_ac": "E1BED6-1", "url": 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"name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BED6", "url": "https://www.uniprot.org/uniprotkb/E1BED6" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "E1BED6", "url": "https://www.uniprot.org/uniprotkb/E1BED6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "E1BED6", "url": "https://www.uniprot.org/uniprotkb/E1BED6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "E1BED6", "url": "https://www.uniprot.org/uniprotkb/E1BED6" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "E1BED6", "url": "https://www.uniprot.org/uniprotkb/E1BED6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BED6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 155, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BED6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BED6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BED6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED6" }, { "id": "PF03939", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03939" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL23 N-terminal", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 66, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEG4-1", "uniprot_ac": "E1BEG4", "uniprot_id": "E1BEG4_BOVIN", "mass": { "chemical_mass": 169315.0, "monoisotopic_mass": 169315.0 }, "refseq": { "ac": "NP_001193129", "name": "zinc finger FYVE domain-containing protein 16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193129" }, "gene_names": [ { "name": "ZFYVE16", "type": "recommended", "evidence": [ { "id": "E1BEG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG4" } ] }, { "name": "ZFYVE16", "type": "synonym", "evidence": [ { "id": "NP_001193129", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193129" } ] } ], "protein_names": [ { "name": "Zinc finger FYVE domain-containing protein 16", "type": "recommended", "evidence": [ { "id": "E1BEG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG4/entry#names_and_taxonomy" } ] }, { "name": "Endofin", "type": "synonym", "evidence": [ { "id": "E1BEG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger FYVE domain-containing protein 16", "type": "synonym", "evidence": [ { "id": "NP_001193129", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193129" } ] } ], "function": [ { "annotation": "May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.", "evidence": [ { "database": "UniProtKB", "id": "E1BEG4", "url": "https://www.uniprot.org/uniprotkb/E1BEG4#function" }, { "database": "UniProtKB", "id": "ARBA00054273", "url": "https://www.uniprot.org/uniprotkb/ARBA00054273#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEG4", "url": "https://www.uniprot.org/uniprotkb/E1BEG4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZFYVE16", "url": "https://www.uniprot.org/uniprotkb/E1BEG4", "locus": { "chromosome": "7", "start_pos": 80618497, "end_pos": 80569078, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021577", "url": "https://www.ensembl.org/id/ENSBTAG00000021577" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021577", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021577", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15729", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15729", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "536671", "url": "https://www.ncbi.nlm.nih.gov/gene/536671", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536671", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536671", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GIDKYVC", "url": "https://omabrowser.org/oma/group/GIDKYVC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEG4", "url": "https://www.orthodb.org/?gene=E1BEG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46319", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46319", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46319:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46319:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11979", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11979", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-201451", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-201451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193129", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BEG4", "url": "https://www.uniprot.org/uniprotkb/E1BEG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEG4-1", "url": "https://www.uniprot.org/uniprotkb/E1BEG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSYFKAAVSDLDRLLDDFEQNPDEQDYLQDAQKAYDSKHYSVSSELTASQVTSLLPKDQQCINCCVSSETGYETNQIALSEKGLGGLTSLQNEKNVTGLDLLSSVDGGTSDEIQPLYMGRCSKPVCDLISDMGNLVHVANSEEDIKKLLPDDLKSSADSLTGLDLSSVSETFCVSSADHGNNAVREEQNDVSLELQNRGISGTTEFGVKVDRALSDSCNYNEKENLEDKKISNQSEPVADFNMPSALTQQSSKAFDAKDHPQHKNQPCELVKAVGCLVKEEEEVPVKAATECLKEGGSTSALSCSLPKDGGLCLNDPNLRDENSKLPDFSFEEDRTAVFIKESAKEDSRNVDLNDNKDVIQDSASALHVSSENTYSSLSCLPVPGSLCGSLIDSKGHGGFLPQNENKDNVQDAVTVHEEIQKKVTSGGESFKETDLLKQDKCKNILHQPLTEKMGDRKVDSNQMVIRVESMDYVDNSSSYTAAESQIELSGASAPESPDHCEGLTFSSNDIDGQDLDYFNIDEGMKSGAPISDAELDAFLTEQYLQTSNIKSFEENINDAKPQMNQIDMKGLDDGNIDNIYFDAEAGATRESPGINMICETIDKQNTAENGSLSLSEKSTVTVEQGLSSSKSEITNELSTSDSNSQSVHVGGARPKQLFSVPSRTRSSKEPNKLDVPNMPESKPRTANTIVATTCTTDSVTDPQVSFDSNYIDIESNFEGGSSFVTANEESLPTNTCKDGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECATVQPLQETQTSSIPSPTTLPISALKQPSVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFSPLLPDMPLMVNTVDHAHSTPVEKPNSETEDTRNEIIQSPTSQVPPVEKLPTNTGTEGLPTSASFTLDDDVFAETEEPSGPTDVLVNSSLPVASTSDYRLLCSIDNVCNKMSLLPDDEDSLPPLLVTSGEKGSVPVVEKHPSHEQIILLLEGEGSCPVTFVLNANLLVNVKLAFYSSDKYWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDSITFTESFLSSKDHGGFLFITPTFQKLDDLLLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAEYKAYPAPLTSIRGRKPLFGDIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKKYSDVMKVINSSNEHVISIGASFSTEADSHLVCIQNDGVYQTQANSATGHPRKVTGASFVVFNGALKASSGFLAKSSIVEDGLMVQITPETMDGLRLALREQKDFKITCGKVDAVDMREYVDICWVDSEEKGNKGVISSVDGMSLQGFPSEKIKLEADFETDEKIVKCTEVFCFLKDQDLSISATRYQFAKEIAMACSAALCPHLKILKSSGMNKIGLRVSIDTDMVEFQAGSEGRLLPQHYLNDLDSALIPVIHGGTSNSTSLPLEIELVFFIIENLFE", "length": 1546, "header": "tr|E1BEG4-1|E1BEG4_BOVIN Isoform 1 of Zinc finger FYVE domain-containing protein 16 OS=Bos taurus OX=9913 GN=ZFYVE16 PE=4 SV=2 CANONICAL=E1BEG4-1" }, "isoforms": [ { "isoform_ac": "E1BEG4-1", "url": "https://www.uniprot.org/uniprotkb/E1BEG4/entry#E1BEG4-1", "sequence": { "sequence": "MDSYFKAAVSDLDRLLDDFEQNPDEQDYLQDAQKAYDSKHYSVSSELTASQVTSLLPKDQQCINCCVSSETGYETNQIALSEKGLGGLTSLQNEKNVTGLDLLSSVDGGTSDEIQPLYMGRCSKPVCDLISDMGNLVHVANSEEDIKKLLPDDLKSSADSLTGLDLSSVSETFCVSSADHGNNAVREEQNDVSLELQNRGISGTTEFGVKVDRALSDSCNYNEKENLEDKKISNQSEPVADFNMPSALTQQSSKAFDAKDHPQHKNQPCELVKAVGCLVKEEEEVPVKAATECLKEGGSTSALSCSLPKDGGLCLNDPNLRDENSKLPDFSFEEDRTAVFIKESAKEDSRNVDLNDNKDVIQDSASALHVSSENTYSSLSCLPVPGSLCGSLIDSKGHGGFLPQNENKDNVQDAVTVHEEIQKKVTSGGESFKETDLLKQDKCKNILHQPLTEKMGDRKVDSNQMVIRVESMDYVDNSSSYTAAESQIELSGASAPESPDHCEGLTFSSNDIDGQDLDYFNIDEGMKSGAPISDAELDAFLTEQYLQTSNIKSFEENINDAKPQMNQIDMKGLDDGNIDNIYFDAEAGATRESPGINMICETIDKQNTAENGSLSLSEKSTVTVEQGLSSSKSEITNELSTSDSNSQSVHVGGARPKQLFSVPSRTRSSKEPNKLDVPNMPESKPRTANTIVATTCTTDSVTDPQVSFDSNYIDIESNFEGGSSFVTANEESLPTNTCKDGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECATVQPLQETQTSSIPSPTTLPISALKQPSVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFSPLLPDMPLMVNTVDHAHSTPVEKPNSETEDTRNEIIQSPTSQVPPVEKLPTNTGTEGLPTSASFTLDDDVFAETEEPSGPTDVLVNSSLPVASTSDYRLLCSIDNVCNKMSLLPDDEDSLPPLLVTSGEKGSVPVVEKHPSHEQIILLLEGEGSCPVTFVLNANLLVNVKLAFYSSDKYWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDSITFTESFLSSKDHGGFLFITPTFQKLDDLLLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAEYKAYPAPLTSIRGRKPLFGDIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKKYSDVMKVINSSNEHVISIGASFSTEADSHLVCIQNDGVYQTQANSATGHPRKVTGASFVVFNGALKASSGFLAKSSIVEDGLMVQITPETMDGLRLALREQKDFKITCGKVDAVDMREYVDICWVDSEEKGNKGVISSVDGMSLQGFPSEKIKLEADFETDEKIVKCTEVFCFLKDQDLSISATRYQFAKEIAMACSAALCPHLKILKSSGMNKIGLRVSIDTDMVEFQAGSEGRLLPQHYLNDLDSALIPVIHGGTSNSTSLPLEIELVFFIIENLFE", "length": 1546, "header": "tr|E1BEG4-1|E1BEG4_BOVIN Isoform 1 of Zinc finger FYVE domain-containing protein 16 OS=Bos taurus OX=9913 GN=ZFYVE16 PE=4 SV=2 CANONICAL=E1BEG4-1" }, "locus": { "chromosome": "7", "start_pos": 80617933, "end_pos": 80585019, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028751.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028751.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028751.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028751.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 988, "start_aa": "Thr", "end_pos": 988, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr988", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:536671", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536671", "resource": "KEGG Pathway" }, { "id": "R-BTA-201451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-201451", "resource": "Reactome", "description": "Signaling by BMP" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ADF6-1", "protein_name": "Zinc finger FYVE domain-containing protein 16", "gene_name": "Zfyve16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSYFKAAVSDLDKLLDDFEQNPEKQDYFQDVQDVYAFNQCSVSSELASPQLALLSKDQRCISSHASSETCCEANETFLQGKIPEGLTSKQNEKNVAGLDLLSSVDASTSDEIQPSCMRRCSKPVCDLISDMGNLVHATSSEEDIKQLLPDDSKSPADTLITLDSSSVSEVLIGLDLSSVSDTLAVSSVDGGSQAVRKEQDTNAGVQSRDNSRIQESGAEVDMALSDSCKYSRTENLKDKMISNELETVDFGMPSVLTEQSSEMSNTKDSPQYQRLPCELLKDDGDLAEEKVGMAGNSTKCLEEGGNIIAMPCKLPKNEEISPNDPTSKDENFKLPDFSVQESRTAVFIKQTVAEDSVKSDLKDNNDVVQVSSSSLHVSSDGVSPSLSCLSLSGSLCGSLVDCNAHGDFLPSDESKGQNNDAVTAHEEIQKSAALDGETDLLKKEKQESMFLQPVNDKEGDGEVELEEMVISGEPLEYPEGTNPAAAGSQMAPPTVSASEAPGQCEALTFSSGDMDGQELDYFNIDESMRSGILVSDAELDAFLKEQSLQNSNTMSFGENASDSQLQMNQIDMKGLCDENAGDRYFNAEAGAAGESGGVVICETTDKENTVQNGGLSVGEKSAIPTERGLSASQPDIRSEVPVPSINTQAVGGARPKQLPSRPPGTSSSQGPSKPHVVGVPAGEPSTANAAAAPTRPADHTPDSQVSFNSNYIDIESNFEGGSSFVTANKDSLPENIRKEGLVLGQKQPTWVPDSEAPNCMNCKVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVICYETINKAQAFERMMSPGGACLKSNHSNECVTAQPLQETQTSSIPSPTALPISALKQPNVEGPCSREQKRVWFADGILPNGEVADTTKLSSGSKRCSDDFSPVLPDAPTVINKVDHTPSPMVEKANNSVGDVLRSEITQSPICRAAPLEILPGSTGAEGLPTAGPFTLEDDVFVDSEEPSTPTVVPANTGLPVASVSDYRLLCGVAKCVCNNISLLPDDDVGLPPLLATSGEDGSVPVVQEHPSHEQIILLLESEGFPPATFVLNANLLVNVKLVFYSSDKYWYFSTNGLHGLGQAEIIILLLCLPNEDTVPKDIFRLFITIYKDASKGKYVENLDNLTFTESFLSSKDHGGFLFITPTFQKLDDLPVPRSPFLCGILIHKLEIPWAKAFPMRLMLRLGAEYKAYPAPLTSVRGRRPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKKYSDVLKVINSSNEHVISIGASFSTEADSHLVCVQSDGVYQTQANSATGQPRKVTGASFVVFNGALKTSSGFLAKSSIVEDGLMVQITPETMDGLRLALREQKDFKIQCGKVDAVDLREYVDICWVDSEERKNKGVISSVDGMSLEGFPSEKIKLETDFETEEKTVKCTEVFCFLKDQDISLSSSSYQFAKEIATACSAALCPHLRTLKSNRMNRIGLRVSVDTDMVEFQAGCEGQLLPQHYLNDLDSALIPVIHGGTSNSTVPLEIELAFFILENLLE", "length": 1547 }, "evidence": [ { "id": "E1BEG4", "url": "https://omabrowser.org/oma/group/E1BEG4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z3T8-1", "protein_name": "Zinc finger FYVE domain-containing protein 16", "gene_name": "ZFYVE16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMGRCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDHDSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIVDFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTSALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDSSSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNSVVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVESQEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICEIVDKQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTRSSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVTANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQTSSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFSPLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLPTSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDEDSLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGESFHPVTFVLNANLLVNVKFIFYSSDKYWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFTESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAEYKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASFVVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLREYVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQDLSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLPQHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF", "length": 1539 }, "evidence": [ { "id": "E1BEG4", "url": "https://omabrowser.org/oma/group/E1BEG4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80U44-1", "protein_name": "Zinc finger FYVE domain-containing protein 16", "gene_name": "Zfyve16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSYFKAAVSGLDKLLDDFEQNPDKQDYLPDAYAFNQCSVSSESASPQLALLSKDQRCISTCASSEACCEDANETFLEGKIHEGLTSRPNEKNVAGLDLLSSVDASTSDEIQPSCMRRCSKPVCDLISDMGNLVHATNSEEDIKQLLPDDPKSSADTLITLDSSSVSEALTVSSVDCGSNAVREEQNNINAGIKNRDISIKELGVKVDMALFDSCKYNRTENLKDKIISNELETVDFDMPSVLMEQSSEMSNTKDNPQYKRLPCELLKDDGCLAEEKVAVAVNNTECLEEGGGSNTIAMPCKLPENEGISPSDPASKDENFKLPDFPLQENRTSVFMKQTVKEDSRNLDLKDNNDIVHVSGDDVPPSLSCLSLSGSLCGSLIHNNEHSDILPPNESEGQNNDAVTIHEEIQKSDVLDGETDLSKKETCRSIFLQPVNEKKGEGKVEVEEMVISGESLESPEDASSAAAAGSPVALSAASVPEAPGPCEGLTFPSSDMDGQELDYFNIDESMRSGILISDAELDAFLKEQCLSNSNTMSAGENVNDSQLQMNQITMKGLHDENAGDIYFNAEAGAAGENGGVGNCETSDKENTENNGLSIGEKGAIPTERELSACQPDIRDELPVPSIKTQAVGGARPKQLLSLPPGTRSSKELNKPDVVDVPESEPCTANATAVSTCSADHIPDSQVSFNSNYIDIESNFEDGSSFVTANKDSLPENKRKESLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVICYETINKAQAFERMMSPGGSCLKSNHSNECATDQPLQETQTSSTPSPTTLPISALKQPNVEGPCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSDDFSPVLPDVPTMINKVDRTHSPTVEKPNNGLGDIIRSEISQSPTCHTAPVERLPGNTGTEGLPMPGPFTLEDDVFVDSEEPSTPTVVPANSGLPVASISDYRLLCSVAKCVCNNISLLPDDDIGLPPLLATSGEDGSVPVVQERPSHEQIILLLEGEGFPPATFVLNANLLVNVKLVLYSSEKYWYFSTNGLHGLGQAEIIVLLQCLPNEDTVPKDIFRLFITIYKDALKGKYIENLDNLTFTESFLNSKDHGGFLFITPTFQNLDGLPVPRSPFLCGILIQKLEIPWAKVFPMRLMLRLGAEYKAYPAPLTSVRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKKYSDVMKVIHSSNEHVISIGASFSTEADSHLVCVQSDGVYQTQANSATGQPRKVTGASFVVFNGALKTSSGFLAKSSIVEDGLMVQITPETMEGLRLALREQKDFRIQCGKVDAVDLREYVDICWVDSEERKNKGVISSVDGMSVEGFPSEKIKLETDFETEEKTVKCTEVFYFLKDQDISILSSSYQFAKEIAVACSAALCPHLRTLKSNRMNKIGLRVSIDTDMVEFQAGCEGQLLPQHYLNDLDSALIPVIHGGTSNSSLPLEIELAFFILENLSE", "length": 1528 }, "evidence": [ { "id": "E1BEG4", "url": "https://omabrowser.org/oma/group/E1BEG4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BEG4", "url": "https://www.uniprot.org/uniprotkb/E1BEG4" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "E1BEG4", "url": "https://www.uniprot.org/uniprotkb/E1BEG4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BEG4", "url": "https://www.uniprot.org/uniprotkb/E1BEG4" } ], "pmid": "" }, { "name": "1-phosphatidylinositol binding", "id": "GO:0005545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005545", "evidence": [ { "database": "UniProtKB", "id": "E1BEG4", "url": "https://www.uniprot.org/uniprotkb/E1BEG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "E1BEG4", "url": "https://www.uniprot.org/uniprotkb/E1BEG4" } ], "pmid": "" }, { "name": "protein targeting to lysosome", "id": "GO:0006622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006622", "evidence": [ { "database": "UniProtKB", "id": "E1BEG4", "url": "https://www.uniprot.org/uniprotkb/E1BEG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1276, "end_pos": 1278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1526, "end_pos": 1528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 831, "end_pos": 833, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" }, { "start_pos": 993, "end_pos": 995, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG4" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 754, "end_pos": 812, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 988 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1276, "end_pos": 1278 }, { "start_pos": 1526, "end_pos": 1528 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 477, "end_pos": 479 }, { "start_pos": 611, "end_pos": 613 }, { "start_pos": 831, "end_pos": 833 }, { "start_pos": 96, "end_pos": 98 }, { "start_pos": 993, "end_pos": 995 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEG6-1", "uniprot_ac": "E1BEG6", "uniprot_id": "E1BEG6_BOVIN", "mass": { "chemical_mass": 18238.0, "monoisotopic_mass": 18238.0 }, "refseq": { "ac": "NP_001178279", "name": "complexin-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178279" }, "gene_names": [ { "name": "CPLX4", "type": "recommended", "evidence": [ { "id": "E1BEG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG6" } ] }, { "name": "CPLX4", "type": "synonym", "evidence": [ { "id": "NP_001178279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178279" } ] } ], "protein_names": [ { "name": "Complexin 4", "type": "synonym", "evidence": [ { "id": "E1BEG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG6/entry#names_and_taxonomy" } ] }, { "name": "complexin-4", "type": "synonym", "evidence": [ { "id": "NP_001178279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178279" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEG6", "url": "https://www.uniprot.org/uniprotkb/E1BEG6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CPLX4", "url": "https://www.uniprot.org/uniprotkb/E1BEG6", "locus": { "chromosome": "24", "start_pos": 58262768, "end_pos": 58286305, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038739", "url": "https://www.ensembl.org/id/ENSBTAG00000038739" } ] } } ], "crossref": [ { "id": "E1BEG6", "url": "https://alphafold.ebi.ac.uk/entry/E1BEG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000038739", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038739", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22809", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22809", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616684", "url": "https://www.ncbi.nlm.nih.gov/gene/616684", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616684", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616684", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SLMGQFQ", "url": "https://omabrowser.org/oma/group/SLMGQFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEG6", "url": "https://www.orthodb.org/?gene=E1BEG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16705:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16705:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178279", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178279", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BEG6", "url": "https://www.uniprot.org/uniprotkb/E1BEG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEG6-1", "url": "https://www.uniprot.org/uniprotkb/E1BEG6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFLMKTMISNQVKNLGLGGGSEEKKEEGGASDPAAAQGMSREEYEEYQKQIIEEKMERDAAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGDDVDLPEDLRKMVDEDQEEEEDKDSILGQLQNLQNMDLDAIKEKAQATFSEIKQTAEQKCAVM", "length": 160, "header": "tr|E1BEG6-1|E1BEG6_BOVIN Isoform 1 of Complexin 4 OS=Bos taurus OX=9913 GN=CPLX4 PE=3 SV=1 CANONICAL=E1BEG6-1" }, "isoforms": [ { "isoform_ac": "E1BEG6-1", "url": "https://www.uniprot.org/uniprotkb/E1BEG6/entry#E1BEG6-1", "sequence": { "sequence": "MAFLMKTMISNQVKNLGLGGGSEEKKEEGGASDPAAAQGMSREEYEEYQKQIIEEKMERDAAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGDDVDLPEDLRKMVDEDQEEEEDKDSILGQLQNLQNMDLDAIKEKAQATFSEIKQTAEQKCAVM", "length": 160, "header": "tr|E1BEG6-1|E1BEG6_BOVIN Isoform 1 of Complexin 4 OS=Bos taurus OX=9913 GN=CPLX4 PE=3 SV=1 CANONICAL=E1BEG6-1" }, "locus": { "chromosome": "24", "start_pos": 58286282, "end_pos": 58263772, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054988.3", "url": "https://www.ensembl.org/id/ENSBTAT00000054988.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050637.1", "url": "https://www.ensembl.org/id/ENSBTAP00000050637.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616684", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616684", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TPW0-1", "protein_name": "Complexin 4", "gene_name": "CPLX4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFLMKTMISNQVKNLGLGGGSEEKKEEGGTSDPAAAHGMTREEYEEYQKQVIEEKMERDAAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGDDVDLPEDLRKMVNEDQEEEEDKDSILGQLQNLQNMDLDTIKEKAQATFTEIKQTAEQKCSVM", "length": 160 }, "evidence": [ { "id": "E1BEG6", "url": "https://omabrowser.org/oma/group/E1BEG6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Y5C1-1", "protein_name": "Complexin 4", "gene_name": "CPLX4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAFLMKSMLSNQVKNLGLGGGGEESKEESTPSDPAAAAGMTREEYEEYQKQMVEEKMERDAAFAQKKAERACLRVHLREKYRLPKSELDENQIQMAGDDVGLPEDLQKMVAEDQIEEEDKDSILGQLQNIQNMDMDAIKEKAQATFTEIKQAAEQKCSVM", "length": 160 }, "evidence": [ { "id": "E1BEG6", "url": "https://omabrowser.org/oma/group/E1BEG6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZM85-1", "protein_name": "Complexin 4", "gene_name": "Cplx4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFFVKNMISNQVKNLGFGGGSEEKKEEGGTSDPAAAKGMTREEYEEYQKQMIEEKMERDAAFTQKKAERACLRVHLRDKYRLPKSEMDETQIQLAGDDVDLPEDLRKMVDEDQDEEEEKDSILGQLQNLQNMDLDTIKEKAQATFTEIKQSAEQKCSVM", "length": 160 }, "evidence": [ { "id": "E1BEG6", "url": "https://omabrowser.org/oma/group/E1BEG6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z7G2-1", "protein_name": "Complexin-4", "gene_name": "CPLX4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFLMKSMISNQVKNLGFGGGSEENKEEGGASDPAAAQGMTREEYEEYQKQMIEEKMERDAAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGDDVDLPEDLRKMVDEDQEEEEDKDSILGQIQNLQNMDLDTIKEKAQATFTEIKQTAEQKCSVM", "length": 160 }, "evidence": [ { "id": "E1BEG6", "url": "https://omabrowser.org/oma/group/E1BEG6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80WM3-1", "protein_name": "Complexin-4", "gene_name": "Cplx4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFFVKNMISNQVKNLGFGGGSEEKKEEGGTSDPAAAKGMTREEYEEYQKQMIEEKMERDAAFTQKKAERACLRVHLRDKYRLPKSEMDETQIQLAGDDVDLPEDLRKMVDEDQDEEEEKDSILGQLQNLQNMDLDTIKEKAQATFTEIKQSAEQKCSVM", "length": 160 }, "evidence": [ { "id": "E1BEG6", "url": "https://omabrowser.org/oma/group/E1BEG6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "E1BEG6", "url": "https://www.uniprot.org/uniprotkb/E1BEG6" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "E1BEG6", "url": "https://www.uniprot.org/uniprotkb/E1BEG6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "E1BEG6", "url": "https://www.uniprot.org/uniprotkb/E1BEG6" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "E1BEG6", "url": "https://www.uniprot.org/uniprotkb/E1BEG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "E1BEG6", "url": "https://www.uniprot.org/uniprotkb/E1BEG6" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031630", "evidence": [ { "database": "UniProtKB", "id": "E1BEG6", "url": "https://www.uniprot.org/uniprotkb/E1BEG6" } ], "pmid": "" }, { "name": "synaptic vesicle exocytosis", "id": "GO:0016079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016079", "evidence": [ { "database": "UniProtKB", "id": "E1BEG6", "url": "https://www.uniprot.org/uniprotkb/E1BEG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEG6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 160, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEG6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEG6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"chemical_mass": 141377.0, "monoisotopic_mass": 141377.0 }, "refseq": { "ac": "XP_024852275", "name": "PR domain zinc finger protein 15 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852275" }, "gene_names": [ { "name": "PRDM15", "type": "recommended", "evidence": [ { "id": "E1BEG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG7" } ] }, { "name": "PRDM15", "type": "synonym", "evidence": [ { "id": "XP_024852275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852275" } ] } ], "protein_names": [ { "name": "PR domain zinc finger protein 15", "type": "recommended", "evidence": [ { "id": "E1BEG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG7/entry#names_and_taxonomy" } ] }, { "name": "PR domain zinc finger protein 15 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024852275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852275" } ] }, { "name": "PR domain-containing protein 15", "type": "synonym", "evidence": [ { "id": "E1BEG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEG7", "url": "https://www.uniprot.org/uniprotkb/E1BEG7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRDM15", "url": "https://www.uniprot.org/uniprotkb/E1BEG7", "locus": { "chromosome": "1", "start_pos": 142066552, "end_pos": 142132976, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021253", "url": "https://www.ensembl.org/id/ENSBTAG00000021253" } ] } } ], "crossref": [ { "id": "E1BEG7", "url": "https://alphafold.ebi.ac.uk/entry/E1BEG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021253", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021253", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19199", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19199", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514566", "url": "https://www.ncbi.nlm.nih.gov/gene/514566", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514566", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514566", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390:SF245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390:SF245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21549", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21549", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23573", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23573", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024852275", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852275", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BEG7", "url": "https://www.uniprot.org/uniprotkb/E1BEG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEG7-1", "url": "https://www.uniprot.org/uniprotkb/E1BEG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"https://www.rhea-db.org/rhea/78547", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78555", "url": "https://www.rhea-db.org/rhea/78555", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEH1-1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRTGLCSRWGGRVLPLLLAYICYLLLGATIFQLLEKQAESQSRDRFQFEKLRFLENYTCLDQQAVEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALVGIPLNVVFLNHLGTGLRAHLTMLERWEDQHRRSQLLQTLGLALFLALGTLLILILPPMIFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYLSVYRSLAAIWILLGLAWLALVLPLGPLLLHRCSQLWLLGRGLGLKEGGAPETNGLPRPQKIPISA", "length": 294, "header": "tr|E1BEH1-1|E1BEH1_BOVIN Isoform 1 of 2P domain potassium channel Talk-1 OS=Bos taurus OX=9913 GN=KCNK16 PE=3 SV=3 CANONICAL=E1BEH1-1" }, "isoforms": [ { "isoform_ac": "E1BEH1-1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1/entry#E1BEH1-1", "sequence": { "sequence": "MPRTGLCSRWGGRVLPLLLAYICYLLLGATIFQLLEKQAESQSRDRFQFEKLRFLENYTCLDQQAVEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALVGIPLNVVFLNHLGTGLRAHLTMLERWEDQHRRSQLLQTLGLALFLALGTLLILILPPMIFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYLSVYRSLAAIWILLGLAWLALVLPLGPLLLHRCSQLWLLGRGLGLKEGGAPETNGLPRPQKIPISA", "length": 294, "header": "tr|E1BEH1-1|E1BEH1_BOVIN Isoform 1 of 2P domain potassium channel Talk-1 OS=Bos taurus OX=9913 GN=KCNK16 PE=3 SV=3 CANONICAL=E1BEH1-1" }, "locus": { "chromosome": "23", "start_pos": 13187689, "end_pos": 13181398, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030656.6", "url": "https://www.ensembl.org/id/ENSBTAT00000030656.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030628.5", "url": "https://www.ensembl.org/id/ENSBTAP00000030628.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 86, "start_aa": "Asn", "end_pos": 86, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn86", "evidence": [ { "id": "E1BEH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEH1#ptm_processing" }, { "id": "PIRSR038061-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038061-1" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:615960", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615960", "resource": "KEGG Pathway" }, { "id": "R-BTA-1299361", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1299361", "resource": "Reactome", "description": "TWIK-related alkaline pH activated K+ channel (TALK)" }, { "id": "R-BTA-5576886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576886", "resource": "Reactome", "description": "Phase 4 - resting membrane potential" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A685-1", "protein_name": "2P domain potassium channel Talk-1", "gene_name": "KCNK16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPHAGLCPCWGGRVLPLLLAYVCYLLLGATIFQLLEKQAEAQSRDQFQFEKLRFLENYTCLDQQALEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALVGIPLNVVFLNHLGTGLRAHLTALERWEDQPRRSQLLQTLGLALFLALGTMLILIFPPMVFSHVEGWSFGEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRTLAAIWILMGLAWLALVLPLGPLLLHRCSQLWLLSRGLGLKEGGAPETDGLPRPQKIPISA", "length": 294 }, "evidence": [ { "id": "E1BEH1", "url": "https://omabrowser.org/oma/group/E1BEH1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7IMU8-1", "protein_name": "2P domain potassium channel Talk-1", "gene_name": "Kcnk16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPRAGLCSCWGGQVLPLLLAYICYLLLGATIFQLLEKQAEAQSRDQFQLEKLRFLENYTCLDQQALEQFVQVILEARVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNHLGTGLRAHLTTLDRWEDHPRHSQLLQVLGLALFLTLGTLVILIFPPMFFSHVEGWSFREGFYFAFITLSTIGFGDYVVGTDPSKHYIAVYRSLAAIWILLGLAWLAVVLSLGSLLLHRCSRLWLLIRGLDLKDGADPDSDPRPQKIPISA", "length": 292 }, "evidence": [ { "id": "E1BEH1", "url": "https://omabrowser.org/oma/group/E1BEH1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0ZJF1-1", "protein_name": "2P domain potassium channel Talk-1", "gene_name": "KCNK16", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPFLTAPNWQISWTPLLVLGYLFYLLLGAMVFQLLEKQAETHSRDQFHLEKLKFLQNYRCLDRQALEQFIQVLMEAWEKGVNPERNSTNPSNWDFSNSFFFAGTVVTTIGYGNRSPSTVAGQVFCVFYALFGVPLNLAFLNQLGKGLNAHLITLERWVQKPGHDQVVQRLAVAVFLTAGTLLFLVFPPLVFCYVEGWSYGEGFYFTFITLSTIGFGDYVVGANPNKHYIPLYRSLTAIWIVFGLAWLALVFNVGADLMEKFLQLKWHKPDLSLSEGAPTKLEDEPEQPRIHIPT", "length": 294 }, "evidence": [ { "id": "E1BEH1", "url": "https://omabrowser.org/oma/group/E1BEH1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZLR9-1", "protein_name": "2P domain potassium channel Talk-1", "gene_name": "Kcnk16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRAGVCSCWGGQVLPLLLAYICYLLLGATIFQRLEKQAEAQSRDQFQLEKLRFLENYTCLDQQALEQFVQVILEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNHLGTGLRAHLTTLDRWEDHPRHSQLLQVLGLALFLTLGTLVILIFPPMFFSHVEGWSFREGFYFAFITLSTIGFGDYVVGTDPSKHYIAVYRSLAAIWILLGLAWLAVVLSLGSLLLHRCSRLWQLIRGLDVKDGAAPGSEPRSQKIPFSA", "length": 292 }, "evidence": [ { "id": "E1BEH1", "url": "https://omabrowser.org/oma/group/E1BEH1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G5E845-1", "protein_name": "Potassium channel, subfamily K, member 16", "gene_name": "Kcnk16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRAGVCGCWGGQVLPLLLAYICYLLLGATIFQLLEKQAEAQSRDQFQLEKLRFLENYTCLDQQALEQFVQVILEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNHLGTGLRAHLTTLDRWEDHPRHSQLLQVLGLALFLTLGTLVILIFPPMFFSHVEGWSFREGFYFAFITLSTIGFGDYVVGTDPSKHYIAVYRSLAAIWILLGLAWLAVVLSLGSLLLHRCSRLWQLIRGLDLKDGAAPDSEPRSQKIPISA", "length": 292 }, "evidence": [ { "id": "E1BEH1", "url": "https://omabrowser.org/oma/group/E1BEH1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96T55-1", "protein_name": "Potassium channel subfamily K member 16", "gene_name": "KCNK16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALILPLGPLLLHRCCQLWLLSLRQGCGAKAAPGRRPRRGSTAARGVQVTPQDFPISKKGLGS", "length": 309 }, "evidence": [ { "id": "E1BEH1", "url": "https://omabrowser.org/oma/group/E1BEH1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" }, { "name": "potassium ion leak channel activity", "id": "GO:0022841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022841", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of action potential", "id": "GO:0098900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098900", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" }, { "name": "regulation of release of sequestered calcium ion into cytosol", "id": "GO:0051279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051279", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" }, { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BEH1", "url": "https://www.uniprot.org/uniprotkb/E1BEH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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"MKKQNVRTLSLILCIFSYLLVGAAVFVALESDTESARKRMLEHKRAELRRKYRFTDGDYQELERVLRQAEPHRAGTQWRFAGSFYFAITVITTIGYGHAAPGTDAGKLFCMLYAGLGIPLTLVMFQSLGERMNTGVRFLLSRMKRALGLQRTEISTQNMVLVGVLSCLGTLCVGAAAFSHFESWTFFHAYYYCFITLTTIGFGDFVALQKKEDLQENQPYVLFSFIYILLGLTVIGAFLNLVVLRFLTLNTEDEKRDAAERASQRASLRASSLRKAPAFRRDSQTHSRTNLLSPRPTPHLRWFCSRVHLDHTSACRNTCAGCSVSSVSCRIHADTAFSSPRSTLSAGLSFTTRRKSL", "length": 357 }, "evidence": [ { "id": "E1BEH3", "url": "https://omabrowser.org/oma/group/E1BEH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8R5I0-1", "protein_name": "Potassium channel subfamily K member 15", "gene_name": "Kcnk15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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Unlike other synaptotagmins, it does not bind Ca(2+) or phospholipids. 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"https://www.ensembl.org/id/ENSBTAP00000004370.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:536820", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536820", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BY95-1", "protein_name": "Synaptotagmin-12", "gene_name": "SYT12", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDSGHMGRYRLSAAASPPRWEVGIYAAGALALLGIAAVNLWKLWRSGSYPAPSPFPNYDYRYLEQKYGTAYSDIKHKHGAAVGSKPLPSRKASLRGADTCESINELGSLELMSRDLGLASYGPLKKSVSADSLNSVSSIGNNFGQDFTVGQVEVSMEYDGKAAALHVTLLQGKDLLEKEDARFESCFMRISLLPAEQIVGISRIQRSAYAVAFDERFSIPLDPAALEEDSLRFSVFGIDEDERNVSTGVAELKLSDLDLTVRPFNAWLYLQDMNKTIDTVGEILLSLSYLPTAERLTVVVVKAKNLVWSNGKGTADPFVKVYLLQDGRKISKKKTAVKRDDTNPVFNEAMIFSVPAIVLQDLSLRVTVAESGEDGRADNTGHVLIGPAASGMGITHWNQMLATLRKPVSMWHPLRRN", "length": 417 }, "evidence": [ { "id": "E1BEH9", "url": "https://omabrowser.org/oma/group/E1BEH9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LK76-1", "protein_name": "Synaptotagmin-12", "gene_name": "SYT12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVDVAEYHLSVIKSPPDWEVGVYAAGALALLGIAAVSLWKLWTSGSFPSPSPFPNYDYRYLQQKYGETYAEARQKRVPAWNAQRASTRGPPSRKGSLSIEDTFESITELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMDYDAASHTLHVAVLQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPAALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKVADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHPVRRN", "length": 421 }, "evidence": [ { "id": "E1BEH9", "url": "https://omabrowser.org/oma/group/E1BEH9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97610-1", "protein_name": "Synaptotagmin-12", "gene_name": "Syt12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVDVTEYHLSVIKSPPGWEVGVYAAGALALLGIAAVSLWKLWTSGSFPSPSPFPNYDYRYLQQKYGEAYVEAKLKRVPPWNAQRTTTRGPPSRKGSLSIEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMDYDGASHTLHVAVLQGKDLLEREEATFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSVPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPGASGMGTTHWNQMLATLRRPVSMWHPVRRN", "length": 421 }, "evidence": [ { "id": "E1BEH9", "url": "https://omabrowser.org/oma/group/E1BEH9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IV01-1", "protein_name": "Synaptotagmin-12", "gene_name": "SYT12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVDVAEYHLSVIKSPPGWEVGVYAAGALALLGIAAVSLWKLWTSGSFPSPSPFPNYDYRYLQQKYGESCAEAREKRVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHAVRRN", "length": 421 }, "evidence": [ { "id": "E1BEH9", "url": "https://omabrowser.org/oma/group/E1BEH9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q920N7-1", "protein_name": "Synaptotagmin-12", "gene_name": "Syt12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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potentiation", "id": "GO:0060291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060291", "evidence": [ { "database": "UniProtKB", "id": "E1BEH9", "url": "https://www.uniprot.org/uniprotkb/E1BEH9" } ], "pmid": "" }, { "name": "regulation of calcium ion-dependent exocytosis", "id": "GO:0017158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017158", "evidence": [ { "database": "UniProtKB", "id": "E1BEH9", "url": "https://www.uniprot.org/uniprotkb/E1BEH9" } ], "pmid": "" }, { "name": "presynaptic modulation of chemical synaptic transmission", "id": "GO:0099171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099171", "evidence": [ { "database": "UniProtKB", "id": "E1BEH9", "url": "https://www.uniprot.org/uniprotkb/E1BEH9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "E1BEH9", 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"https://www.uniprot.org/uniprotkb/E1BEJ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RNF103", "url": "https://www.uniprot.org/uniprotkb/E1BEJ4", "locus": { "chromosome": "11", "start_pos": 48307239, "end_pos": 48278953, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020947", "url": "https://www.ensembl.org/id/ENSBTAG00000020947" } ] } } ], "crossref": [ { "id": "E1BEJ4", "url": "https://alphafold.ebi.ac.uk/entry/E1BEJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020947", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020947", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "511639", "url": "https://www.ncbi.nlm.nih.gov/gene/511639", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511639", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511639", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDWLAWP", "url": "https://omabrowser.org/oma/group/PDWLAWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEJ4", "url": "https://www.orthodb.org/?gene=E1BEJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15302:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15302:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178337", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178337", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BEJ4", "url": "https://www.uniprot.org/uniprotkb/E1BEJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEJ4-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNAERLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVEKWDNKSYMTDIGVYNMPSYILRTPEGIYRYGNHTGEYISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNINNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSEGSQDIENDSDSESTDTLSSEKEVFEDKLSIIHSSPGRASHCDAEACSCANKYCQTSPYERKGRSYGSYSANEDMEPDWLTWPADMLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQHQPLSNDFPS", "length": 685, "header": "tr|E1BEJ4-1|E1BEJ4_BOVIN Isoform 1 of Ring finger protein 103 OS=Bos taurus OX=9913 GN=RNF103 PE=4 SV=2 CANONICAL=E1BEJ4-1" }, "isoforms": [ { "isoform_ac": "E1BEJ4-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ4/entry#E1BEJ4-1", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNAERLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVEKWDNKSYMTDIGVYNMPSYILRTPEGIYRYGNHTGEYISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNINNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSEGSQDIENDSDSESTDTLSSEKEVFEDKLSIIHSSPGRASHCDAEACSCANKYCQTSPYERKGRSYGSYSANEDMEPDWLTWPADMLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQHQPLSNDFPS", "length": 685, "header": "tr|E1BEJ4-1|E1BEJ4_BOVIN Isoform 1 of Ring finger protein 103 OS=Bos taurus OX=9913 GN=RNF103 PE=4 SV=2 CANONICAL=E1BEJ4-1" }, "locus": { "chromosome": "11", "start_pos": 48301743, "end_pos": 48279109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027899.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027899.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027899.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027899.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511639", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511639", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N206-1", "protein_name": "E3 ubiquitin-protein ligase RNF103 isoform X1", "gene_name": "Rnf103", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFAKLDQPPAFFSALSIKFTGRVEFIFVNVENWDNKSYMTDIGVYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLRLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRSNNDEVNANNLEWLSSLWDWYTSYLFHPIASLQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSESSQDTENDSDSDNMDTFSSKDVFEDKQSIVHSSLGRTSHCDAGACSCANKYCQTSPRERKGRSYGSHNTNEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPFAQQQLLSNDVPS", "length": 683 }, "evidence": [ { "id": "E1BEJ4", "url": "https://omabrowser.org/oma/group/E1BEJ4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0YSH5-1", "protein_name": "Ring finger protein 103", "gene_name": "RNF103", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MWLKLCFLLLYFLVLFVLARVFEAVVWYETGFFATQLVDPVALSFRKLRTILECRGLGHSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKVHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWLKSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNSEHLREEWNRSDQYRVKIYLFASLDQPPAFFSALSVKFTGRVEFIFVNVENWDNKSYMAEIGVYKTPSYILRTPEGIYRYGSNAGEFISLRAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLFRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNNNNDEVNANNLEWLSSLWDWYTSYLFHPIASFQHFPFDSDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPVWRFKCLGVHSDEEMLETLQDGESDSDTENREVFSSEKDISEDDEPSTFHRPRAGEPRSRAGSCSCASTCCHKEPCERKARSYGSYSTADEPDWSAWPPEMLHCTECVVCLENFERGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWASYKKKQPYTHPQPLSSDSPS", "length": 684 }, "evidence": [ { "id": "E1BEJ4", "url": "https://omabrowser.org/oma/group/E1BEJ4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SVD1-1", "protein_name": "Ring finger protein 103", "gene_name": "RNF103", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYDAEHLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWDNKSYMTDIGIYSMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSVQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNNNNDEVNANNLEWLSSLWDWYTSYLFHPITSFQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSEGSQDTEHESDSESTDTLSSEKEVFEEKQSIVHSSPGQTSHSDAEACSCASKYCQTTAYERKGRSYGSYSSNEDMEPDWLTWPADMLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQHQSLSNDVPS", "length": 685 }, "evidence": [ { "id": "E1BEJ4", "url": "https://omabrowser.org/oma/group/E1BEJ4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O00237-1", "protein_name": "E3 ubiquitin-protein ligase RNF103", "gene_name": "RNF103", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNAEHLKEEWNKSDQYWLKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWDNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNNNNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSEGSQDTENDSESENTDTLSSEKEVFEDKQSVLHNSPGTASHCDAEACSCANKYCQTSPCERKGRSYGSYNTNEDMEPDWLTWPADMLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQHQPLSNDVPS", "length": 685 }, "evidence": [ { "id": "E1BEJ4", "url": "https://omabrowser.org/oma/group/E1BEJ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EPZ8-1", "protein_name": "E3 ubiquitin-protein ligase RNF103", "gene_name": "Rnf103", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWNNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLRLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRSNNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVDSDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGAQSEEEMSESSQDTENDSDSDNTDTFSSSKDVFEDKQNVHSSPGRTSRCDTEACSCANKCVSSPCERKRRSYGSHNTKEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQQQPLSNDAPS", "length": 682 }, "evidence": [ { "id": "E1BEJ4", "url": "https://omabrowser.org/oma/group/E1BEJ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9R1W3-1", "protein_name": "E3 ubiquitin-protein ligase RNF103", "gene_name": "Rnf103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWNNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYDYSLRLLRYSNTTTLASWVRADWMFYTSHPALFLSTYLGHGLLIDYFEKKRRRSNNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVDSDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSESSQDTENDSDSDNMDTFSSSKDIFEDKQSVVHSSPGRTSHCDTEACSCANKCESSPCERKRRSYGSHNTDEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQQQPLSNDVPS", "length": 683 }, "evidence": [ { "id": "E1BEJ4", "url": "https://omabrowser.org/oma/group/E1BEJ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ4", "url": "https://www.uniprot.org/uniprotkb/E1BEJ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ4", "url": "https://www.uniprot.org/uniprotkb/E1BEJ4" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ4", "url": "https://www.uniprot.org/uniprotkb/E1BEJ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ4", "url": "https://www.uniprot.org/uniprotkb/E1BEJ4" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ4", "url": "https://www.uniprot.org/uniprotkb/E1BEJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEJ4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 685, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEJ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEJ4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEJ4" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 621, "end_pos": 663, "start_aa": "Cys", "end_aa": "Arg", 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"Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540239", "url": "https://www.ncbi.nlm.nih.gov/gene/540239", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540239", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540239", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NCISPRP", "url": "https://omabrowser.org/oma/group/NCISPRP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEL0", "url": "https://www.orthodb.org/?gene=E1BEL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46294", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46294", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46294:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46294:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BEL0", "url": "https://www.uniprot.org/uniprotkb/E1BEL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEL0-1", "url": "https://www.uniprot.org/uniprotkb/E1BEL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESRKDMVMFLDGGQLGTLVGKRVSNLSEAVGSPLPEPPEKMVPRGCLSPRAGPPAARERGGGGLEEEPVDGLAGSAAGPGAESRAAGAAVLGPGPPAASADSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGPGSEALASSPNGSSETSKSNGSGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGPLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGTAAGGPCSCLACHGGPANGLAPRAAAASDFTCASTSRSDSFLSFAPSVLSKASSVALDQREEVPLTR", "length": 404, "header": "tr|E1BEL0-1|E1BEL0_BOVIN Isoform 1 of Homeobox even-skipped homolog protein 1 OS=Bos taurus OX=9913 GN=EVX1 PE=3 SV=1 CANONICAL=E1BEL0-1" }, "isoforms": [ { "isoform_ac": "E1BEL0-1", "url": "https://www.uniprot.org/uniprotkb/E1BEL0/entry#E1BEL0-1", "sequence": { "sequence": "MESRKDMVMFLDGGQLGTLVGKRVSNLSEAVGSPLPEPPEKMVPRGCLSPRAGPPAARERGGGGLEEEPVDGLAGSAAGPGAESRAAGAAVLGPGPPAASADSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGPGSEALASSPNGSSETSKSNGSGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGPLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGTAAGGPCSCLACHGGPANGLAPRAAAASDFTCASTSRSDSFLSFAPSVLSKASSVALDQREEVPLTR", "length": 404, "header": "tr|E1BEL0-1|E1BEL0_BOVIN Isoform 1 of Homeobox even-skipped homolog protein 1 OS=Bos taurus OX=9913 GN=EVX1 PE=3 SV=1 CANONICAL=E1BEL0-1" }, "locus": { "chromosome": "4", "start_pos": 68801018, "end_pos": 68797648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027866.2", "url": "https://www.ensembl.org/id/ENSBTAT00000027866.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027866.1", "url": "https://www.ensembl.org/id/ENSBTAP00000027866.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540239", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540239", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X641-1", "protein_name": "Even-skipped homeobox 1", "gene_name": "EVX1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MESRKEMVMFLEGTQLGALVGKRVPNLTETVRSPAPEPQEKMIPRNCLSPRPGPLSSRERGGGGGGGGGEDEEEVEVLPGTGTVPESRSAAAALLGAGQQPPGTEPPSSKGQQSSSDTESDFYEEIEVSCTPDCATGSAEYQHSKGPCPEARAGSPGGGGDHPKGGGGGGGGGGSQGPLSCSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAATGNLPYPFPSHLPLPYYSHMGIGATSASAAAPFSTPLRPLDTFRVLSHPYPRPELLCAFRHPSLYPAPSHGLGSAGGSPCSCLACHGSPSNGLAQRSAGSDFTCSATTRTDSFLTFTPSVLSKATSVSIDQREEVPLTR", "length": 408 }, "evidence": [ { "id": "E1BEL0", "url": "https://omabrowser.org/oma/group/E1BEL0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1LQ30-1", "protein_name": "Homeobox even-skipped homolog protein 1", "gene_name": "Evx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESRKDMVMFLDGGQLGSLVGKRVSNLSEAVSSPLPEPPEKMVPHGCLSPRAGPPTSRERGGGGQEEEPVDGLAGSAAGLGAEPRSAGAAMLGPGPPVPSADSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKAPDSDALGSSPNSGSEAPKSNGGSGGSGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGPLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAGGPCSCLACHSGPSNGLAPRAAAASDFTCASTSRSDSFLTFAPSVLSKASSVALDQREEVPLTR", "length": 407 }, "evidence": [ { "id": "E1BEL0", "url": "https://omabrowser.org/oma/group/E1BEL0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SHT9-1", "protein_name": "Homeobox even-skipped homolog protein 1", "gene_name": "EVX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESRKDMVMFLDGGQLGTLVGKRVSNLSEAVGSPLPEPPEKMVPRSCLSPRAGPPAARERGGGGLEEEPVDGLAGSAAGPGAESRAAGAAVLGPGPPAASADSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGPGSEALASSPNGSSEAPKSNGSGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGPLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGTAAGGPCSCLACHGGPANGLAPRAAAAAAASDFTCASTSRSDSFLTFAPSVLSKASSVALDQREEVPLTR", "length": 407 }, "evidence": [ { "id": "E1BEL0", "url": "https://omabrowser.org/oma/group/E1BEL0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P23683-1", "protein_name": "Homeobox even-skipped homolog protein 1", "gene_name": "Evx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESRKDMVMFLDGGQLGTLVGKRVSNLSEAVSSPLPEPPEKMVPHGCLSPRAGPPTSRERGGGGQEEEPVDGLAGSAAGLGAEPRSAGAAMLGPGPPVPSADSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKAPGSDALGSSPTSGSEAPKSNGGSGGSGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGPLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAAAAAAAGPCSCLACHSGPANGLAPRAAAAAAASDFTCASTSRSDSFLTFAPSVLSKASSVAALDQREEVPLTR", "length": 416 }, "evidence": [ { "id": "E1BEL0", "url": "https://omabrowser.org/oma/group/E1BEL0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49640-1", "protein_name": "Homeobox even-skipped homolog protein 1", "gene_name": "EVX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESRKDMVVFLDGGQLGTLVGKRVSNLSEAVGSPLPEPPEKMVPRGCLSPRAVPPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGSLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAGGPCSCLACHSGPANGLAPRAAAASDFTCASTSRSDSFLTFAPSVLSKASSVALDQREEVPLTR", "length": 407 }, "evidence": [ { "id": "E1BEL0", "url": "https://omabrowser.org/oma/group/E1BEL0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BEL0", "url": "https://www.uniprot.org/uniprotkb/E1BEL0" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "E1BEL0", "url": "https://www.uniprot.org/uniprotkb/E1BEL0" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "E1BEL0", "url": "https://www.uniprot.org/uniprotkb/E1BEL0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BEL0", "url": "https://www.uniprot.org/uniprotkb/E1BEL0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BEL0", "url": "https://www.uniprot.org/uniprotkb/E1BEL0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BEL0", "url": "https://www.uniprot.org/uniprotkb/E1BEL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEL0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 404, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEL0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEL0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL0" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 238, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 26, "end_pos": 28 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEL1-1", "uniprot_ac": "E1BEL1", "uniprot_id": "E1BEL1_BOVIN", "mass": { "chemical_mass": 31541.0, "monoisotopic_mass": 31541.0 }, "refseq": { "ac": "XP_002707835", "name": "NK1 transcription factor-related protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002707835" }, "gene_names": [ { "name": "NKX1-2", "type": "recommended", "evidence": [ { "id": "E1BEL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL1" } ] }, { "name": "NKX1-2", "type": "synonym", "evidence": [ { "id": "XP_002707835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002707835" } ] } ], "protein_names": [ { "name": "NK1 homeobox 2", "type": "synonym", "evidence": [ { "id": "E1BEL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL1/entry#names_and_taxonomy" } ] }, { "name": "NK1 transcription factor-related protein 2", "type": "synonym", "evidence": [ { "id": "XP_002707835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002707835" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEL1", "url": "https://www.uniprot.org/uniprotkb/E1BEL1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NKX1-2", "url": "https://www.uniprot.org/uniprotkb/E1BEL1", "locus": { "chromosome": "26", "start_pos": 44082637, "end_pos": 44086546, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020918", "url": "https://www.ensembl.org/id/ENSBTAG00000020918" } ] } } ], "crossref": [ { "id": "E1BEL1", "url": "https://alphafold.ebi.ac.uk/entry/E1BEL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "617982", "url": "https://www.ncbi.nlm.nih.gov/gene/617982", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617982", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617982", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYLGPFY", "url": "https://omabrowser.org/oma/group/AYLGPFY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEL1", "url": "https://www.orthodb.org/?gene=E1BEL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24340:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24340:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002707835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002707835", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BEL1", "url": "https://www.uniprot.org/uniprotkb/E1BEL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BEL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREAKKSLAEAEARKDASRDPIPQREAPDAAGHGAGLASPLEGSEAEEAEEEDEDVEDARRRRGERAAHLQAGLTLSPEARAAASAAGESGAGGLAGSPGSPRPRRRRAEPNSSKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAEGAAQAGGGAPQPGTAAASGGAGGSPGPPGPGAHPFQTFPSYSAANVLFPAAASFPLTAAGGSFTPFLGHSYLTPFYAPHL", "length": 301, "header": "tr|E1BEL1-1|E1BEL1_BOVIN Isoform 1 of NK1 homeobox 2 OS=Bos taurus OX=9913 GN=NKX1-2 PE=3 SV=3 CANONICAL=E1BEL1-1" }, "isoforms": [ { "isoform_ac": "E1BEL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BEL1/entry#E1BEL1-1", "sequence": { "sequence": "MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREAKKSLAEAEARKDASRDPIPQREAPDAAGHGAGLASPLEGSEAEEAEEEDEDVEDARRRRGERAAHLQAGLTLSPEARAAASAAGESGAGGLAGSPGSPRPRRRRAEPNSSKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAEGAAQAGGGAPQPGTAAASGGAGGSPGPPGPGAHPFQTFPSYSAANVLFPAAASFPLTAAGGSFTPFLGHSYLTPFYAPHL", "length": 301, "header": "tr|E1BEL1-1|E1BEL1_BOVIN Isoform 1 of NK1 homeobox 2 OS=Bos taurus OX=9913 GN=NKX1-2 PE=3 SV=3 CANONICAL=E1BEL1-1" }, "locus": { "chromosome": "26", "start_pos": 44086477, "end_pos": 44083641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027865.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027865.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027865.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027865.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], 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"sequence": { "sequence": "MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDASSRDPVRQLETPDAAGPGAGQASPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTAAAPGSPFAPFLGPSYLTPFYAPRL", "length": 310 }, "evidence": [ { "id": "E1BEL1", "url": "https://omabrowser.org/oma/group/E1BEL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BEL1", "url": "https://www.uniprot.org/uniprotkb/E1BEL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BEL1", "url": "https://www.uniprot.org/uniprotkb/E1BEL1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BEL1", "url": "https://www.uniprot.org/uniprotkb/E1BEL1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BEL1", "url": "https://www.uniprot.org/uniprotkb/E1BEL1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BEL1", "url": "https://www.uniprot.org/uniprotkb/E1BEL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEL1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 301, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEL1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEL1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL1" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEL5-1", "uniprot_ac": "E1BEL5", "uniprot_id": "E1BEL5_BOVIN", "mass": { "chemical_mass": 25387.0, "monoisotopic_mass": 25387.0 }, "refseq": {}, "gene_names": [ { "name": "PSMC3IP", "type": "recommended", "evidence": [ { "id": "E1BEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL5" } ] } ], "protein_names": [ { "name": "Homologous-pairing protein 2 homolog", "type": "recommended", "evidence": [ { "id": "E1BEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL5/entry#names_and_taxonomy" } ] }, { "name": "PSMC3-interacting protein", "type": "synonym", "evidence": [ { "id": "E1BEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL5/entry#names_and_taxonomy" } ] }, { "name": "Proteasome 26S ATPase subunit 3-interacting protein", "type": "synonym", "evidence": [ { "id": "E1BEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEL5", "url": "https://www.uniprot.org/uniprotkb/E1BEL5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PSMC3IP", "url": "https://www.uniprot.org/uniprotkb/E1BEL5", "locus": { "chromosome": "19", "start_pos": 42650230, "end_pos": 42655096, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020907", "url": "https://www.ensembl.org/id/ENSBTAG00000020907" } ] } } ], "crossref": [ { "id": "E1BEL5", "url": "https://alphafold.ebi.ac.uk/entry/E1BEL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020907", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020907", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR010776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BEL5", "url": "https://www.orthodb.org/?gene=E1BEL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15938", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15938", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15938:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15938:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BEL5", "url": 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"MSKGRSEAAAGALSLSVASGILLKYLQEQNRPYSAQDVFGNLQREHGLGKTAVVKALEQLAQQGKIKEKMYGKQKIYFADQDQFDVVSDADLQGLDAKILALTAKVQSLQQSCRHMEAELKELTSALTTPEMQKEIEELKKECAGYRERLKNIKAATNHVTPEEKEQVYKERQKYHKEWRQRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDHNVKLPDP", "length": 223, "header": "tr|E1BEL5-1|E1BEL5_BOVIN Isoform 1 of Homologous-pairing protein 2 homolog OS=Bos taurus OX=9913 GN=PSMC3IP PE=3 SV=2 CANONICAL=E1BEL5-1" }, "locus": { "chromosome": "19", "start_pos": 42654897, "end_pos": 42650846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027851.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027851.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027851.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027851.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "condensed 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], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "E1BEL5", "url": "https://www.uniprot.org/uniprotkb/E1BEL5" } ], "pmid": "" }, { "name": "recombinase activator activity", "id": "GO:0120230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120230", "evidence": [ { "database": "UniProtKB", "id": "E1BEL5", "url": "https://www.uniprot.org/uniprotkb/E1BEL5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "E1BEL5", "url": "https://www.uniprot.org/uniprotkb/E1BEL5" } ], "pmid": "" }, { "name": "meiotic joint molecule formation", "id": "GO:0000709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000709", "evidence": [ { "database": "UniProtKB", "id": "E1BEL5", "url": "https://www.uniprot.org/uniprotkb/E1BEL5" } ], "pmid": "" }, { "name": "meiotic strand invasion involved in reciprocal meiotic recombination", "id": "GO:0010774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010774", "evidence": [ { "database": "UniProtKB", "id": "E1BEL5", "url": "https://www.uniprot.org/uniprotkb/E1BEL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEL5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 223, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEL5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEL5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL5" }, { "id": "PF07106", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homologous-pairing protein 2 winged helix", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 79, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL5" }, { "id": "PF18517", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18517" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Leucine zipper with capping helix", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 216, "start_aa": "Val", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEL9-1", "uniprot_ac": "E1BEL9", "uniprot_id": "E1BEL9_BOVIN", "mass": { "chemical_mass": 61800.0, "monoisotopic_mass": 61800.0 }, "refseq": { "ac": "XP_010814604", "name": "bifunctional coenzyme A synthase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814604" }, "gene_names": [ { "name": "COASY", "type": "recommended", "evidence": [ { "id": "E1BEL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ] }, { "name": "COASY", "type": "synonym", "evidence": [ { "id": "XP_010814604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814604" } ] } ], "protein_names": [ { "name": "Bifunctional coenzyme A synthase", "type": "recommended", "evidence": [ { "id": "E1BEL9", "database": "UniProtKB", "url": 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"database": "UniProtKB", "id": "ARBA00094100", "url": "https://www.uniprot.org/uniprotkb/ARBA00094100#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEL9", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "COASY", "url": "https://www.uniprot.org/uniprotkb/E1BEL9", "locus": { "chromosome": "19", "start_pos": 42642777, "end_pos": 42638703, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046746", "url": "https://www.ensembl.org/id/ENSBTAG00000046746" } ] } } ], "crossref": [ { "id": "E1BEL9", "url": "https://alphafold.ebi.ac.uk/entry/E1BEL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046746", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046746", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02022", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02022", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02164", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02164", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614728", "url": "https://www.ncbi.nlm.nih.gov/gene/614728", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614728", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614728", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BEL9", "url": "https://www.orthodb.org/?gene=E1BEL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10695:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10695:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-196783", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196783", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010814604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814604", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "18245", "url": "https://www.rhea-db.org/rhea/18245", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19801", "url": "https://www.rhea-db.org/rhea/19801", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0P0I1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0I1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEL9", "url": "https://www.uniprot.org/uniprotkb/E1BEL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEL9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVFRSGLLVLTTPLTSLAPRLAPILSSAARLVNHTLYVHLQPGMSLGGPAQPQSSPVQATFEVLDFITHLYAGADVHRHLDVRILLTNIRTKSCLPPLPTSVQNLAHPPEVVLTDFQTLDGSQYNPAKQQLERYATSCYSCCPKLSSVLLYPDYGPAVSPAGSLGVHLPSTIRPTSPVARSAKQPVRGHQRGAVGGTFDRLHNAHKVLLSVACILAQEQLVVGVADKDLLKSKLLPELLQPYTERVEHLSEFLVDIKPSLTFDIIPLLDPYGPAGSDPSLEFLVVSEETYRGGMAVNRFRLENDLEELTLYQIQLLKDLNHKENEEDKVSSSSFRQQMLGNLLRPPYKRPELPPGFYVIGLTGISGSGKSSVAQRLKGLGAYIIDSDHLGHRAYAPGGPAYQPVVEAFGTDILHKDGIINRKVLGSRVFGNKKQLKILTDIMWPVIAKLAREEMDQAVAEGKRVCVIDAAMLLEAGWQNMVHEVWTVVIPETEAIRRIMERDGLSEAAAQSRLQSQMSGQQLVDQSHVVLSTMWEPHVTQRQVEKAWALLQKRISEAPSGP", "length": 562, "header": "tr|E1BEL9-1|E1BEL9_BOVIN Isoform 1 of Bifunctional coenzyme A synthase OS=Bos taurus OX=9913 GN=COASY PE=3 SV=2 CANONICAL=E1BEL9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P0I1-1", "url": "https://www.uniprot.org/uniprotkb/E1BEL9/entry#A0ABI0P0I1-1", "sequence": { "sequence": "MAVFRSGLLVLTTPLTSLAPRLAPILSSAARLVNHTLYVHLQPGMSLGGPAQPQSSPVQATFEVLDFITHLYAGADVHRHLDVRILLTNIRTKSCLPPLPTSVQNLAHPPEVVLTDFQTLDGSQYNPAKQQLERYATSCYSCCPKLSSVLLYPDYGPAVSPAGSLGVHLPSTIRPTSPVARSAKQPVRGHQRGAVGGTFDRLHNAHKVLLSVACILAQEQLVVGVADKDLLKSKLLPELLQPYTERVEHLSEFLVDIKPSLTFDIIPLLDPYGPAGSDPSLEFLVVSEETYRGGMAVNRFRLENDLEELTLYQIQLLKDLNHKENEEDKVSSSSFRQQMLGNLLRPPYKRPELPPGFYVIGLTGISGSGKSSVAQRLKGLGAYIIDSDHLGHRAYAPGGPAYQPVVEAFGTDILHKDGIINRKVLGSRVFGNKVNTHLSKGSAATARPGGGDPVNLSVLAPNASLHRLFPTTCSLGLASSLGEGELGPPLPFPSLEAAEDTHGHYVASYRKAGQRGDGSGCG", "length": 522, "header": "tr|A0ABI0P0I1-1|A0ABI0P0I1_BOVIN Computationally mapped isoform of Coenzyme A synthase OS=Bos taurus OX=9913 GN=COASY PE=4 SV=1 CANONICAL=E1BEL9-1" }, "locus": { "chromosome": "19", "start_pos": 42641799, "end_pos": 42639197, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153958.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153958.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104299.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104299.1" } ] } }, { "isoform_ac": "E1BEL9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEL9/entry#E1BEL9-1", "sequence": { "sequence": "MAVFRSGLLVLTTPLTSLAPRLAPILSSAARLVNHTLYVHLQPGMSLGGPAQPQSSPVQATFEVLDFITHLYAGADVHRHLDVRILLTNIRTKSCLPPLPTSVQNLAHPPEVVLTDFQTLDGSQYNPAKQQLERYATSCYSCCPKLSSVLLYPDYGPAVSPAGSLGVHLPSTIRPTSPVARSAKQPVRGHQRGAVGGTFDRLHNAHKVLLSVACILAQEQLVVGVADKDLLKSKLLPELLQPYTERVEHLSEFLVDIKPSLTFDIIPLLDPYGPAGSDPSLEFLVVSEETYRGGMAVNRFRLENDLEELTLYQIQLLKDLNHKENEEDKVSSSSFRQQMLGNLLRPPYKRPELPPGFYVIGLTGISGSGKSSVAQRLKGLGAYIIDSDHLGHRAYAPGGPAYQPVVEAFGTDILHKDGIINRKVLGSRVFGNKKQLKILTDIMWPVIAKLAREEMDQAVAEGKRVCVIDAAMLLEAGWQNMVHEVWTVVIPETEAIRRIMERDGLSEAAAQSRLQSQMSGQQLVDQSHVVLSTMWEPHVTQRQVEKAWALLQKRISEAPSGP", "length": 562, "header": "tr|E1BEL9-1|E1BEL9_BOVIN Isoform 1 of Bifunctional coenzyme A synthase OS=Bos taurus OX=9913 GN=COASY PE=3 SV=2 CANONICAL=E1BEL9-1" }, "locus": { "chromosome": "19", "start_pos": 42642452, "end_pos": 42639197, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027845.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027845.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027845.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027845.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 176, "start_aa": "Thr", "end_pos": 176, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr176", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:614728", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614728", "resource": "KEGG Pathway" }, { "id": "R-BTA-196783", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196783", "resource": "Reactome", "description": "Coenzyme A biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "dephospho-CoA kinase activity", "id": "GO:0004140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004140", "evidence": [ { "database": "UniProtKB", "id": "E1BEL9", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ], "pmid": "" }, { "name": "pantetheine-phosphate adenylyltransferase activity", "id": "GO:0004595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004595", "evidence": [ { "database": "UniProtKB", "id": "E1BEL9", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BEL9", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "E1BEL9", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "E1BEL9", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BEL9", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "coenzyme A biosynthetic process", "id": "GO:0015937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015937", "evidence": [ { "database": "UniProtKB", "id": "E1BEL9", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18245", "name": "", "equation": "3'-dephospho-CoA + ATP = ADP + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL9-1" ], "evidence": [ { "id": "18245", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18245" } ] }, { "id": "19801", "name": "", "equation": "(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL9-1" ], "evidence": [ { "id": "19801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19801" } ] }, { "id": "R-BTA-196754", "name": "COASY transfers an adenylyl group from ATP to PPANT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL9-1" ], "evidence": [ { "id": "R-BTA-196754", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196754" } ] }, { "id": "R-BTA-196773", "name": "COASY phosphorylates DP-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL9-1" ], "evidence": [ { "id": "R-BTA-196773", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196773" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BEL9", "gene_name": "COASY", "activity": [ { "ec_number": "2.7.1.24", "activity": "3'-dephospho-CoA + ATP = ADP + CoA + H(+).", "evidence": [ { "id": "E1BEL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ] }, { "ec_number": "2.7.7.3", "activity": "(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate.", "evidence": [ { "id": "E1BEL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ] }, { "ec_number": "2.7.1.24", "activity": "", "evidence": [ { "id": "E1BEL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ] }, { "ec_number": "2.7.7.3", "activity": "", "evidence": [ { "id": "E1BEL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEL9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 562, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEL9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEL9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL9" }, { "id": "PF01467", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01467" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytidyltransferase-like", "eco_id": "ECO_0000259", "start_pos": 195, "end_pos": 337, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.24", "ec_name": "3'-dephospho-CoA + ATP = ADP + CoA + H(+).", "evidence": [ { "id": "2.7.1.24", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.24" }, { "id": "2.7.1.24", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.24" } ] }, { "ec_number": "2.7.7.3", "ec_name": "(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate.", "evidence": [ { "id": "2.7.7.3", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.3" }, { "id": "2.7.7.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.7.3" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 176 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376721" }, "gene_names": [ { "name": "OR52A24", "type": "recommended", "evidence": [ { "id": "E1BEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEN1" } ] }, { "name": "OR52A24", "type": "synonym", "evidence": [ { "id": "NP_001376721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376721" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEN1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 52A5", "type": "synonym", "evidence": [ { "id": "NP_001376721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376721" } ] }, { "name": "olfactory receptor family 52 subfamily A member 24", "type": "synonym", "evidence": [ { "id": "NP_001376721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376721" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BEN1", "url": "https://www.uniprot.org/uniprotkb/E1BEN1#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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}, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507662", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507662", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VSHSFCE", "url": "https://omabrowser.org/oma/group/VSHSFCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEN1", "url": "https://www.orthodb.org/?gene=E1BEN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", 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PE=3 SV=1 CANONICAL=E1BEV3-1" }, "isoforms": [ { "isoform_ac": "E1BEV3-1", "url": "https://www.uniprot.org/uniprotkb/E1BEV3/entry#E1BEV3-1", "sequence": { "sequence": "MGEHNLLNPGFVGPLVNIHTGDTFYFPNFRASGAQLPGLPSLSYPRRDNVCSLPWPSAEPCNGYPQPYLGSPVSLNPPFGRTCELARVEDSKGYYREPCAEGGGGLKREERGRDPGPGVGPGAALLPLEPSGPPALGFKYDYAAGGGGGDGGAGPPHDPPSCQSLESDSSSSLLNEGNKGAGAGDPGSLVSPLNPGGGLAASGAPWYPIHSRSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRLLLREQALSFF", "length": 281, "header": "tr|E1BEV3-1|E1BEV3_BOVIN Isoform 1 of Homeobox C12 OS=Bos taurus OX=9913 GN=HOXC12 PE=3 SV=1 CANONICAL=E1BEV3-1" }, "locus": { "chromosome": "5", "start_pos": 26077683, "end_pos": 26076095, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001223.4", "url": "https://www.ensembl.org/id/ENSBTAT00000001223.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001223.2", "url": "https://www.ensembl.org/id/ENSBTAP00000001223.2" } ] } } ], "glycosylation": [], "phosphorylation": [], 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"sequence": "MASSSGSRSEFIAGGKYKLVRKIGSGSFGKVYLAINITNGEEVAVKLEPQKARQPQLLYESRLYKLLQGGVGIPRIWWYGQEKDYNVLVMDLLGPSLEELFNYCSRRFTMKTVLMLADQMISRIEYLHTKDFIHRDIKPDNFLMASSNSNQLFLVDFGLAKRYRDSKTKQHIPYKEKKSLTGTARYASLNSHLGIEQSRRDDMESLGYVLMYFNRSSLPWQGIKTATMKQKYEKICESKMATPIEALCNGFPSEFATYLNYCRGLRFEEAPDYTYLRQLFRSLFRTLNYQYDYAFDWILKQRAAQQAASSSGQGQQAQTATTTGKKTDQKKE", "length": 332, "header": "tr|E1BEW4-1|E1BEW4_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=LOC613515 PE=3 SV=2 CANONICAL=E1BEW4-1" }, "isoforms": [ { "isoform_ac": "E1BEW4-1", "url": "https://www.uniprot.org/uniprotkb/E1BEW4/entry#E1BEW4-1", "sequence": { "sequence": "MASSSGSRSEFIAGGKYKLVRKIGSGSFGKVYLAINITNGEEVAVKLEPQKARQPQLLYESRLYKLLQGGVGIPRIWWYGQEKDYNVLVMDLLGPSLEELFNYCSRRFTMKTVLMLADQMISRIEYLHTKDFIHRDIKPDNFLMASSNSNQLFLVDFGLAKRYRDSKTKQHIPYKEKKSLTGTARYASLNSHLGIEQSRRDDMESLGYVLMYFNRSSLPWQGIKTATMKQKYEKICESKMATPIEALCNGFPSEFATYLNYCRGLRFEEAPDYTYLRQLFRSLFRTLNYQYDYAFDWILKQRAAQQAASSSGQGQQAQTATTTGKKTDQKKE", "length": 332, "header": "tr|E1BEW4-1|E1BEW4_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=LOC613515 PE=3 SV=2 CANONICAL=E1BEW4-1" }, "locus": { "chromosome": "X", "start_pos": 50695739, "end_pos": 50694657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000057200.2", "url": "https://www.ensembl.org/id/ENSBTAT00000057200.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048708.2", "url": "https://www.ensembl.org/id/ENSBTAP00000048708.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E1BEW4", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BEW4", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BEW4", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BEW4", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BEW4", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "E1BEW4", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "E1BEW4", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", 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"A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEW5-1", "uniprot_ac": "E1BEW5", "uniprot_id": "E1BEW5_BOVIN", "mass": { "chemical_mass": 32817.0, "monoisotopic_mass": 32817.0 }, "refseq": { "ac": "NP_001179539", "name": "protein phosphatase PTC7 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179539" }, "gene_names": [ { "name": "PPTC7", "type": "recommended", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] }, { "name": "PPTC7", "type": "synonym", "evidence": [ { "id": "NP_001179539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179539" } ] } ], "protein_names": [ { "name": "Protein phosphatase", "type": "recommended", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5/entry#names_and_taxonomy" } ] }, { "name": "PTC7 protein phosphatase homolog", "type": "synonym", "evidence": [ { "id": "NP_001179539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179539" } ] }, { "name": "protein phosphatase PTC7 homolog", "type": "synonym", "evidence": [ { "id": "NP_001179539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179539" } ] } ], "function": [ { "annotation": "Protein phosphatase that plays an essential role in mitochondrial metabolism and biogenesis. Positively regulates biosynthesis of the ubiquinone, coenzyme Q. Dephosphorylates the ubiquinone biosynthesis protein COQ7 which is likely to lead to its activation. Serves as a crucial sensor for mitophagy, though the underlying mechanism remains ambiguous. May dephosphorylate BNIP3 and NIX and thereby directly regulates mitophagy receptor function and stability. Alternatively, promotes SCF-FBXL4-dependent ubiquitination and degradation of BNIP3 and NIX independently of its catalytic activity to restrain mitophagy.", "evidence": [ { "database": "UniProtKB", "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5#function" }, { "database": "UniProtKB", "id": "ARBA00055082", "url": "https://www.uniprot.org/uniprotkb/ARBA00055082#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PPTC7", "url": "https://www.uniprot.org/uniprotkb/E1BEW5", "locus": { "chromosome": "17", "start_pos": 54410956, "end_pos": 54453671, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018332", "url": "https://www.ensembl.org/id/ENSBTAG00000018332" } ] } } ], "crossref": [ { "id": "E1BEW5", "url": "https://alphafold.ebi.ac.uk/entry/E1BEW5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018332", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018332", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "525355", "url": "https://www.ncbi.nlm.nih.gov/gene/525355", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:525355", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525355", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ANTIAWM", "url": "https://omabrowser.org/oma/group/ANTIAWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEW5", "url": "https://www.orthodb.org/?gene=E1BEW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12320", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12320", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12320:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12320:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07228", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07228", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179539", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179539", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEW5-1", "url": "https://www.uniprot.org/uniprotkb/E1BEW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGGGGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 307, "header": "tr|E1BEW5-1|E1BEW5_BOVIN Isoform 1 of Protein phosphatase OS=Bos taurus OX=9913 GN=PPTC7 PE=3 SV=1 CANONICAL=E1BEW5-1" }, "isoforms": [ { "isoform_ac": "E1BEW5-1", "url": "https://www.uniprot.org/uniprotkb/E1BEW5/entry#E1BEW5-1", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGGGGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 307, "header": "tr|E1BEW5-1|E1BEW5_BOVIN Isoform 1 of Protein phosphatase OS=Bos taurus OX=9913 GN=PPTC7 PE=3 SV=1 CANONICAL=E1BEW5-1" }, "locus": { "chromosome": "17", "start_pos": 54453472, "end_pos": 54411960, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024393.4", "url": "https://www.ensembl.org/id/ENSBTAT00000024393.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024393.2", "url": "https://www.ensembl.org/id/ENSBTAP00000024393.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:525355", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525355", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A8D0-1", "protein_name": "Protein phosphatase", "gene_name": "PPTC7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDTRDYSLVTASCGFGKDFRKGILKKGMCYGDDACFVARHRTADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTAGYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPTYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 297 }, "evidence": [ { "id": "E1BEW5", "url": "https://omabrowser.org/oma/group/E1BEW5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A520-1", "protein_name": "Protein phosphatase", "gene_name": "Pptc7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGGSGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 307 }, "evidence": [ { "id": "E1BEW5", "url": "https://omabrowser.org/oma/group/E1BEW5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RNM7-1", "protein_name": "Protein phosphatase", "gene_name": "PPTC7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGSGSGGGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 307 }, "evidence": [ { "id": "E1BEW5", "url": "https://omabrowser.org/oma/group/E1BEW5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O64730-1", "protein_name": "Probable protein phosphatase 2C 26", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAIPVTRMMVPHAIPSLRLSHPNPSRVDFLCRCAPSEIQPLRPELSLSVGIHAIPHPDKVEKGGEDAFFVSSYRGGVMAVADGVSGWAEQDVDPSLFSKELMANASRLVDDQEVRYDPGFLIDKAHTATTSRGSATIILAMLEEVGILKIGNVGDCGLKLLREGQIIFATAPQEHYFDCPYQLSSEGSAQTYLDASFSIVEVQKGDVIVMGSDGLFDNVFDHEIVSIVTKHTDVAESSRLLAEVASSHSRDTEFESPYALEARAKGFDVPLWKKVLGKKLTGGKLDDVTVIVAKVVSS", "length": 298 }, "evidence": [ { "id": "E1BEW5", "url": "https://omabrowser.org/oma/group/E1BEW5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38797-1", "protein_name": "Protein phosphatase 2C homolog 7, mitochondrial", "gene_name": "PTC7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFANVGFRTLRVSRGPLYGSCSQIISFSKRTFYSSAKSGYQSNNSHGDAYSSGSQSGPFTYKTAVAFQPKDRDDLIYQKLKDSIRSPTGEDNYFVTSNNVHDIFAGVADGVGGWAEHGYDSSAISRELCKKMDEISTALAENSSKETLLTPKKIIGAAYAKIRDEKVVKVGGTTAIVAHFPSNGKLEVANLGDSWCGVFRDSKLVFQTKFQTVGFNAPYQLSIIPEEMLKEAERRGSKYILNTPRDADEYSFQLKKKDIIILATDGVTDNIATDDIELFLKDNAARTNDELQLLSQKFVDNVVSLSKDPNYPSVFAQEISKLTGKNYSGGKEDDITVVVVRVD", "length": 343 }, "evidence": [ { "id": "E1BEW5", "url": "https://omabrowser.org/oma/group/E1BEW5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6NVE9-1", "protein_name": "Protein phosphatase PTC7 homolog", "gene_name": "Pptc7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGGGGSSGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 310 }, "evidence": [ { "id": "E1BEW5", "url": "https://omabrowser.org/oma/group/E1BEW5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NI37-1", "protein_name": "Protein phosphatase PTC7 homolog", "gene_name": "PPTC7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 304 }, "evidence": [ { "id": "E1BEW5", "url": "https://omabrowser.org/oma/group/E1BEW5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W0E2-1", "protein_name": "Protein phosphatase", "gene_name": "Dmel\\CG12091", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHSSLSWTSRAISRALRSSFSTLLETATGGGSGAAAKGATKSGATPGSSGAPRPRFVSVVCGFAKDNLRHKYKPGKYGEDSWFKASTASADVMGVADGVGGWRSYGIDPGEFSSFLMRTCERLVQCSHFNPQRPVNLLAYSYCELMEQKKPILGSSTACVLILNRETSTVHTANIGDSGFVVVREGQVVHKSEEQQHYFNTPFQLSLPPPGHGPNVLSDSPESADTMSFPVRDGDVILIATDGVFDNVPEDLMLQVLSEVEGERDPVKLQMTANSLALMARTLSLNSEFLSPFALSARRNNIQARGGKPDDITVVLATVAM", "length": 321 }, "evidence": [ { "id": "E1BEW5", "url": "https://omabrowser.org/oma/group/E1BEW5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of mitophagy", "id": "GO:1901525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901525", "evidence": [ { "database": "UniProtKB", "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ], "pmid": "" }, { "name": "regulation of ubiquinone biosynthetic process", "id": "GO:0010795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010795", "evidence": [ { "database": "UniProtKB", "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ], "pmid": "" }, { "name": "positive regulation of ubiquinone biosynthetic process", "id": "GO:1904775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904775", "evidence": [ { "database": "UniProtKB", "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "E1BEW5", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEW5-1", "A0AAA9TV14-1", "A0AAA9S745-1", "A0A3Q1MV48-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "F1MBQ1-1", "A0AAA9RTM1-1", "A0AAF6YJP2-1", "P48452-1", "F1MI99-1", "G3N3B3-1", "O62830-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "A6H772-1", "O62829-1", "P61287-1", "A0AAA9U0H6-1", "Q3ZBF9-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q0P594-1", "Q1RMV9-1", "Q2KJ36-1", "Q2PC20-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0A3Q1N224-1", "E1BMD4-1", "A0AAF6DLF7-1", "F1N580-1", "F1MQM7-1", "F1MW60-1", "F1N719-1", "E1BF95-1", "E1BIE7-1", "F1MEZ2-1", "F1MM08-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLF7-1", "F1MI92-1", "A0A3Q1MV48-1", "E1BEW5-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "A0ABI0P1A3-1", "F1MBQ1-1", "A0AAA9RTM1-1", "G3N3B3-1", "A0AAF6YJP2-1", "P48452-1", "O62829-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "Q0P594-1", "A6H772-1", "O62830-1", "P61287-1", "A0AAA9U0H6-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q1RMV9-1", "Q2KJ36-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "E1BIZ2-1", "F1MI99-1", "F1MP34-1", "F1MEZ2-1", "F1MQM7-1", "F1MM08-1", "F1N719-1", "A0AAA9T455-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0AAA9TV14-1", "A0AAA9S745-1", "F1N580-1", "E1BMD4-1", "E1BF95-1", "E1BIE7-1", "A0A3Q1N224-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1MLC5", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] } ] }, { "uniprot_ac": "A0A3Q1MV48", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] } ] }, { "uniprot_ac": "A0A3Q1MZU1", "gene_name": "CTDSPL2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] } ] }, { "uniprot_ac": "A0A3Q1N224", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] } ] }, { "uniprot_ac": "A0A3Q1N5B2", "gene_name": "CDC14B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S454", "gene_name": "LOC112441581", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S454" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S454" } ] } ] }, { "uniprot_ac": "A0AAA9S745", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] } ] }, { "uniprot_ac": "A0AAA9SCR0", "gene_name": "LOC112441582", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCR0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCR0" } ] } ] }, { "uniprot_ac": "A0AAA9SWY4", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] } ] }, { "uniprot_ac": "A0AAA9T455", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] } ] }, { "uniprot_ac": "A0AAA9TD32", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD32" } ] } ] }, { "uniprot_ac": "A0AAA9TT76", "gene_name": "PPP3CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT76" } ] } ] }, { "uniprot_ac": "A0AAA9TV14", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TV14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TV14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YJP2", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] } ] }, { "uniprot_ac": "A0ABI0P1A3", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0ABI0P1A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0ABI0P1A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ] } ] }, { "uniprot_ac": "A5PJZ2", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A5PJZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A5PJZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJZ2" } ] } ] }, { "uniprot_ac": "A6H772", "gene_name": "PPP4C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A6H772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H772" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A6H772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H772" } ] } ] }, { "uniprot_ac": "E1B9Y5", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] } ] }, { "uniprot_ac": "E1BAB2", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] } ] }, { "uniprot_ac": "E1BBD9", "gene_name": "LOC112445820", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] } ] }, { "uniprot_ac": "E1BEW5", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] } ] }, { "uniprot_ac": "E1BF95", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] } ] }, { "uniprot_ac": "E1BIE7", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] } ] }, { "uniprot_ac": "E1BIZ2", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] } ] }, { "uniprot_ac": "E1BMD4", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] } ] }, { "uniprot_ac": "F1MBQ1", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MI92", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MW60", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1N580", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] } ] }, { "uniprot_ac": "F1N719", "gene_name": "PPP5C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] } ] }, { "uniprot_ac": "F6RRD7", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] } ] }, { "uniprot_ac": "G3N3B3", "gene_name": "PPM1N", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] } ] }, { "uniprot_ac": "O62829", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] } ] }, { "uniprot_ac": "O62830", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62830" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62830" } ] } ] }, { "uniprot_ac": "P0C591", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] } ] }, { "uniprot_ac": "P48452", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48452" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48452" } ] } ] }, { "uniprot_ac": "P61287", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P61287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61287" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P61287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61287" } ] } ] }, { "uniprot_ac": "P67774", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P67774", "database": "UniProtKB", 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"o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"categories": [ "Protein" ] }, { "id": "E1BEY3", "url": "https://www.uniprot.org/uniprotkb/E1BEY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEY3-1", "url": "https://www.uniprot.org/uniprotkb/E1BEY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALRNHSTITEFILTGLSDDPHIQALLFVLFLVIYLLTVMGNLTMLLVIRADSHLHTPMYFFLSNLSFLDLCFSSVTVPKLLKDLLSEKKTISVEGCLTQVFFVFITAGTEAFLLSMMAYDRYAAICHPLLYGQLMSTQLCVKLILASWGLASLNSVIIVLLAVNLDFCEAQTIHHYTCELPSLFPLSCSDVSVNIDILICSILLHGLGTFLPVVFSYARIVSTILSISSTTGRSKAFSTCSSHLIAVILFFGSGLIRYLMPSSGSSLDLLSSLQYSAVTPMLNPLIYSLKNMEVKAAVKRTLGKYLQYFK", "length": 311, "header": "tr|E1BEY3-1|E1BEY3_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR8S8 PE=3 SV=2 CANONICAL=E1BEY3-1" }, "isoforms": [ { "isoform_ac": "E1BEY3-1", "url": "https://www.uniprot.org/uniprotkb/E1BEY3/entry#E1BEY3-1", "sequence": { "sequence": 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"site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 280, "start_aa": "Thr", "end_pos": 280, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr280", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:515887", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515887", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R2E8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100622582", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALRNHSSITEFILIGLSNDPHVETLLFVLFLGIYLLTIIGNLTMLLVIRADSSLHTPMYFFLSNLSFLDLCFSSVTVPKLLEDLLSEEKTISVEGCLTQVFFVFITAGTEAFLLSVMAYDRYAAICHPLLYGQVMSIQLCVRLVLISWGLASVNASVIVLLAINLDFCDAQTIHHYTCELPSLFPLSCSDISINIDILICLILLHGLGTFLPVFFSYVRIVSTILSISSTTGRSKAFSTCSSHLIAVILFFGSGLVRYLMPTSGSPLDLLSSLQYSAVTPMLNPLIYSLKNMEVKAAVKRTWEKYLQYFRL", "length": 312 }, "evidence": [ { "id": "E1BEY3", "url": "https://omabrowser.org/oma/group/E1BEY3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IJ10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763846", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAWRNHSAITEFILTGLSDDPLIQALLFVLFLGIYLLTMTGNLMMLLVIRADSHLHTPMYFFLSNLSFLDLCFSSVTIPKLLKDLLSEKKSISIEGCLAQVFFIFITAGTEAFLLSMMAYDRYAAVCHPLLYGQIMSNELCRKLVLLSWGLASLSSLVIVLLAVNLDFCEATTIHHYMCELPSLFPLSCSDISINVDILICSTLLHGLGTFLPIFFSYARIVSTILSVKSTTGRSKAFNTCSSHLIAVVLFFGSGLVRYLMPTSGSSLDLLSSLQYSAVTPMLNPLIYSLKNKEVKAAVKRTLGKCLLYLE", "length": 311 }, "evidence": [ { "id": "E1BEY3", "url": "https://omabrowser.org/oma/group/E1BEY3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5USB8-1", "protein_name": "Olfactory receptor", "gene_name": "Or8s8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARSNHSGITEFVLTGLSDDPLIQALLFALFLGIYILTMTGNLMMLVVIRADSHLHTPMYYFLSNLSFLDLCFSSVTVPKLLKDLLSAKKSISVEGCLAQVFFVFITAGTEAFLLSMMAYDRYAAVCHPLLYGQMMSNELCLKLVLLSWGLASLSSVVIVLLAVNLDFCEAYTIHHYTCELPSLFPLSCSDISINVDVLICSTLLHGLGTFLPIFFSYARIVSTVLSMKSTTGRSKAFNTCSSHLIAVVLFFGSGLVRYLMPTSGSSLDLLSSLQYSAVTPMLNPLIYSLKNQEVKTAVKRTLGKCLRYLE", "length": 311 }, "evidence": [ { "id": "E1BEY3", "url": "https://omabrowser.org/oma/group/E1BEY3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VET6-1", "protein_name": "Olfactory receptor", "gene_name": "Or8s8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWSNHSVITEFVLTGLSDDPLIQALLFALFLGIYVLTMTGNLTMLLVITADSHLHTPMYFFLSNLSFLDLCFSSVTVPKLLKDLLSAKKTISVEGCLAQVFFVFITAGTEAFLLSMMAYDRYAAVCHPLLYGQMMSNELCLKLVLLSWGLASLSSVVIVLLAVNLDFCEAYTIHHYTCELPSLFPLSCSDISINVDILICSTLLHGLGTFLPIFFSYARIVSTVLSMESTTGRSKAFNTCSSHLIAVVLFFGSGLIRYLMPTSGSSLDLLSSLQYSAVTPMLNPLIYSLKNQEVKAAVRRTLGKCLRYLE", "length": 311 }, "evidence": [ { "id": "E1BEY3", "url": "https://omabrowser.org/oma/group/E1BEY3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BEY3", "url": "https://www.uniprot.org/uniprotkb/E1BEY3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "E1BEY3", "url": "https://www.uniprot.org/uniprotkb/E1BEY3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BEY3", "url": "https://www.uniprot.org/uniprotkb/E1BEY3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BEY3", "url": "https://www.uniprot.org/uniprotkb/E1BEY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEY3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEY3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEY3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEY3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 280 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BEZ9-1", "uniprot_ac": "E1BEZ9", "uniprot_id": "E1BEZ9_BOVIN", "mass": { "chemical_mass": 37453.0, "monoisotopic_mass": 37453.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "C-type lectin domain-containing protein", "type": "recommended", "evidence": [ { "id": "E1BEZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEZ9", "url": "https://www.uniprot.org/uniprotkb/E1BEZ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BEZ9", "locus": {} } ], "crossref": [ { "id": "E1BEZ9", "url": "https://alphafold.ebi.ac.uk/entry/E1BEZ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048082", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048082", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VWASAHS", "url": "https://omabrowser.org/oma/group/VWASAHS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24024:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24024:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09006", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09006", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BEZ9", "url": "https://www.uniprot.org/uniprotkb/E1BEZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEZ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLPLSMLLLLTQPWRSLGAEIMIYSQKTLANTCTLVMCSPLEGSLPGRDGQDGREGPRGEKGDPGRAGTMGLPGPAGPIGPKGDNGSAGEPRPKGDPGPPGPPGIPGSAGRQGPSGKQGSMGPPGTPGPKGETGPKGGVGAPGMQGFRGPTDLKGERGAPGETGAPGRAGEAGPAGAIGPQSPSGARGPPGLKGDRGNPGERGAKGESGLAEVNALRQRVTILDRQLQCFQNAFSQYKKAVLFPDARSVVVKIFKMAGAVISYLGSEHQEQLAFPRSAAENEAVTQVVRAQKKNAYLSMNDISTEGKFTYPTGKILVYSNWANGEPNKSDEGQPENCVEISPDGKWNDVPCSKQLLVICEF", "length": 363, "header": "tr|E1BEZ9-1|E1BEZ9_BOVIN Isoform 1 of C-type lectin domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=E1BEZ9-1" }, "isoforms": [ { "isoform_ac": "E1BEZ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ9/entry#E1BEZ9-1", "sequence": { "sequence": "MLLLPLSMLLLLTQPWRSLGAEIMIYSQKTLANTCTLVMCSPLEGSLPGRDGQDGREGPRGEKGDPGRAGTMGLPGPAGPIGPKGDNGSAGEPRPKGDPGPPGPPGIPGSAGRQGPSGKQGSMGPPGTPGPKGETGPKGGVGAPGMQGFRGPTDLKGERGAPGETGAPGRAGEAGPAGAIGPQSPSGARGPPGLKGDRGNPGERGAKGESGLAEVNALRQRVTILDRQLQCFQNAFSQYKKAVLFPDARSVVVKIFKMAGAVISYLGSEHQEQLAFPRSAAENEAVTQVVRAQKKNAYLSMNDISTEGKFTYPTGKILVYSNWANGEPNKSDEGQPENCVEISPDGKWNDVPCSKQLLVICEF", "length": 363, "header": "tr|E1BEZ9-1|E1BEZ9_BOVIN Isoform 1 of C-type lectin domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=E1BEZ9-1" }, "locus": { "chromosome": "28", "start_pos": 35544434, "end_pos": 35535068, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028716.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028716.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028716.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028716.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 128, "start_aa": "Thr", "end_pos": 128, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr128", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BEZ9", "url": "https://www.uniprot.org/uniprotkb/E1BEZ9" } ], "pmid": "" }, { "name": 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"E1BEZ9", "url": "https://www.uniprot.org/uniprotkb/E1BEZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BEZ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 363, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BEZ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BEZ9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ9" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": 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"length": 1791, "header": "tr|E1BF00-1|E1BF00_BOVIN Isoform 1 of Pappalysin 2 OS=Bos taurus OX=9913 GN=PAPPA2 PE=3 SV=3 CANONICAL=E1BF00-1" }, "locus": { "chromosome": "16", "start_pos": 58036053, "end_pos": 57724441, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024358.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024358.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024358.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024358.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 112, "start_aa": "Thr", "end_pos": 112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 947, "start_aa": "Thr", "end_pos": 947, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr947", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:538320", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538320", "resource": "KEGG Pathway" }, { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JU68-1", "protein_name": "Pappalysin 2", "gene_name": "Pappa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMCWKVLRISLVVLAGWAFSTTNSELGWTRKKYLAQRAHLNQALLEGERCWLAYKVRRPRCAPQHHPFGVYPSHHENYLRSYPVGMQQTQYAEWSQRSTERQAPSGVPRDLTENPAGVKRKSEQPAAPWVGDGPIGQSQLLRDDDTYLGKGGSKEALGEPAIRGSSETAVSTITTFTYQKGPTAETQRKGQSKSRLPRQVQKRQAEDMTRDPQNTPQDVQLWPKDPLKHGDSNSPLEGTIQNGGGASAQRAETFNPQGGLPVLYFSGKRERLLLRPEVLAEIPREAFTVEAWVRPEGGQSNPAIIAGVFDNCSHTVNDKGWALGIRSGKDKGQRDARFFFSLRTDRMKKATTVIGHSRYQPGTWTHVAATYDGQHMALYVDGTRVAASPDQSGPLNSPFMASCRSLLLGGDNSENGHYFRGYLGTLVIWSTALSQLHLQHSPQHPSGVDELTTLILTATFDPLKEQWAPFRDETYPLMEVFQDSESQPEILSPLQPPPCGQTACDNVELISQYNTHGPLRREKVVRYQVVNICDDEGLHPIVSDLQIRRQHEALNQAFSRYNISWQLSVHRVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGFDGGDCRLQGRCYSWNRRDGLCHMECNNMLNDFDDGDCCDPEVTDVRKTCFDPDSPKRAYMSVKELKEALQLNSTHFLNVYFASSVREDLAGSATWPWDKDALSHLGGVVLNPAYYGMLGHTNIMIHEVGHVLGLYHVFKGVSERESCDDPCRETVPSMETGDLCADTAPTPKSKLCRDPEPANDTCGFTLFPRAPFNNYMSYTDDDCTDNFTPNQVARMHCYLDLVYQQWSESQKPTPIPIPPMVIGQTHKSLTIHWLPPISGVVYDRTPDSMCGACTEDGTFRQYVYKASSGRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPELHLNHMNMTVPCPAEGCSLELLFQHPVQADTLTLWVTYLSVNSSKAFFDIEILLEHKESMHLGPLNTFCDMPLTIKLHVDEKVVGAKVYTFDERMEIDAALLTSRPSSSLCSGCRPVSYQVLREPPFSSGLPMVVTHPHRKFTDTEVIPGQVYQYQVQAEAGGELGEASPPLSHIHGGPYCGDGKVERSMGEMCDDGDLLNGDGCSRACELEEGFNCAGEPSLCYRYEGDGICEAFEKKTSIIDCGLHTPEGYLDQWASQAYSYHEDKKKCPVSLVTGEPHSLICTSRHPDSSPYHLFPGWFPCVFNLKKDQDAGREKSKDSLQKENEIWLEVCFNKPGVAVAIFIFLASDGLNPGEHQQATVTPYLIDVSGNNHSLGTYGLSCQHNPLVINVSHHANVNPQHTSTMLLNFSSPLVGISAVALRTSSQTISSSLSNCIPEQNHQGQSCAQRPCGEQGRCVPLLLDHTDMVNCTSSGPGHMECAITCQRGYVLQTSSGQYLRNMQKEILLTCSSGHWNNNVNCKRLDCGVPDSSLVNYANFSCTEGTDFLKRCSISCVPPAKLQGLNPWLTCLEDGLWSLPEVYCKLECEAPPVIPNAHLLRPHCLEGNHDVSTICKYECKPGYYVKESSGSQGKNKFLKIQCLDDGTWEQGSCVPVVCEPPPPVFEGMYDCTNGFKLDSQCVLNCNQETERIPILCTKEGLWTQEFKLCENLQGECPPPTSELNSVEYKCGQGYGIGAVCSPSCVIPPSDPVILPENVTTDTLEHWMEPVKVQSIVCTGRRQWHPDPSLVHCIQSCEPFQADGWCDTINNRAYCNYDGGDCCSSTLSSKKVIPFAADCDSDECTCRDPKAEENQ", "length": 1788 }, "evidence": [ { "id": "E1BF00", "url": "https://omabrowser.org/oma/group/E1BF00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3B0D2-1", "protein_name": "Pappalysin-2 isoform X2", "gene_name": "pappa2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMFFRLLAIILAVFHTWPLNSAQSDHIQKYKRTLAQRAERALAGEQCGSVSRKRPPRSTAHHYPLAGVSGRYTRLTDLHLRKTHTVRSCAGDCSSSAVELTNWDANEKETFVQPQEETFIWKKEGKRAQWVTDPASAKSLNPSKRISKGLPLQTEQGADFIDSLSKTRRVARSISEFNNEEVIPEKSYNHHTEYSTENEEYSGEQEGLQSTAGELWKAEVRDVPTKWMTGIYFSGQAEQLKVNPAFAIELPRSRFTIELWVKPEGGQNNPSIIAGVFDNCSHPLSEKGWSVGIQAADPTGRKDGRFFFSLRTDRSLKSTTIIGHQRYQPDSWTHVVASYDGHKMALYVDNFKAGESSEQSGDLYSSYIKACRLFLLGGDQSDHEHSFRGHLGGVALWGYARSHEELLKSHQPHSERQSPLLSQWADFSEVENQWVPYKDRHNPVIVALPVPELQLVSPFLPPPCGVTVCDNFDIALSYNKHWQMRAEKKIRYRVVNICKDNGSDPSVSLQQIQRQHQALEDAFHPYNITLELSIHTVYNSSLQRRFILSNCHIAKVGNRHCDPECDHPLTGHDGGDCLRMGPCYNWKRRDGVCNPECNSIHYDYDDGDCCDPEVTDVAKTCFDPESPQRAYLSVKELKELLHLSSSDMLNVFFANNSAREELAGVATWPWAKEALTHQGGMILNPAYFGTKGHNNTMIHEMGHIFGLYHVFKGVSERESCDDPCQETTASMETGDLCADTAPTPKSKACHDPDPVNDTCGLTQYKNTPYNNYMSYTDDDCTNHFTPNQVARMHCYIDLVYKTWVHERKPTPVPLAPVVVGQKADSVSIHWLNPISGPLAHREGDMNCQLCDENGALHQYAHEATSPHACDSTGYWTPEEAVGAPDVYQPCEPSMQAWSPEVNLYEPNMTTPCPQSEGCVLELHFLQPVLPDSLTVWITYTSANQKAIANIVFITENGELIHTGPQHAFCDIPLTLHVHTSKKVKAIKISTFDKKLEIDAVLLTSRPQNPLCSGCRPLLYRVIREPPIREDQSPAIVRQPSYTDSDVQKDVQYLYRIQVESDGLFSELSPSLLYTHGEHFCGDATLQGTEDCDDGNLLDGDGCSKKCHVEAGFKCHGQPSLCYVFEGDGVCEEFEKGSSIQDCGFFTPQGFNDQWASTALGSHQDQRCPASRVTGEPALTQMCKSQYFDINEIVAHEAWSPCTAHYTQDQSVWLQVGFERPGVAASVIIYLAYDGSWHGENCKKTVTIELCDTNGKRHLLGSYEVSCQRNPLVVNVTHNLSVPFYQTSAVQLNFSSSQVAVVAVALRTSCHFSAFALTGCVRRLCSTESCSPVNIEHASVRCTPALDSKHCSVSCHRGFILTVLHGQSLSSHQEAELICVHGVWDRVVSCQPVDCGPPPPSHVYFASFSCPWGTTFGKQCTFSCNAPAILQGESDTLVCLEDGLWSYPEAYCKIECADPPFLPNATLLVPHCQGGGHDVGTVCRFKCNPGYYVTGTLNKKPRKKFLRLECLEGGTWQEGSCSPVTCPPLRPMFEGMYSCTNNFDFDSVCTLQCSDPTEKPSIRCTKDGRWTEDFTMCKKIVGSCQAPPEVNLVEYSCDEGFDVGAACYPTCIVPLSDPVVLANGSSADTVEHWMVPTKVQSIVCTGMLKWYPNPEQIHCIQSCEPFGGDGWCDTINNRAYCQYDGGDCCPSTLSSGKVIQFGVDCDQDECTCRDPEAGENKPKEKQQPGAP", "length": 1730 }, "evidence": [ { "id": "E1BF00", "url": "https://omabrowser.org/oma/group/E1BF00/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PZ87-1", "protein_name": "Pappalysin 2", "gene_name": "Pappa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMCWKVLRISLVVLTGWALSTTNSEQGWTRKKFLAQKEHLNQVLLEGERCWLGYKVRRPRTAPQHHLFGVYPSRLENYPRSYPVGTQQQTLYAEWSQRSPERQAPSGIPRDLTENPAGARRESQQPAAPWVGDGPIGQSQLLRNDDTYLGEGGSKEALGEPAIQGSSEIAVSTIATFAYQKGPTAETQRKGQSKSRLPRQVQKRQAEDMTGDPQNTPQGFQLWPKEPLKHGDSDSPLEGTIQNGGGASLRRVETFNSQGGLPVLYFTGKRERLLLRPEVLAEIPREAFTVEAWVRPEGGQSNPAIIAGVFDNCSHTVNDKGWALGIRSGKDKGWRDARFFFSLRTDRMKKATIVTGHSRYQPGMWTHVAATYDGQHTALYVDGTRVASSRDQFGPLNSPFMASCRSLILGGDSSEDGHYFRGYLGTLVIWSTALSQTHLQHSPLHPSAADELTTLILTATFDPLMEQWAPFRDDLYPRLEVLQDSESQPEILSPLQPPPCGQTACDNVELISQYNKHGPLRREKVIRYQVVNIYDDEGLHPIVSDHQIRRQHEALNQAFSRYNISWQLSVHRVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGFDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPEVTDVRKTCFDPDSPKRAYMSVKELKEALQLNSTHFLNVYFASSVREDLAGSATWPWDKEALSHLGGVVLNPTYYGMLGHTNIMIHEVGHVLGLYHVFKGVSERESCDDPCRETVPSMETGDLCADTAPTPKSKLCRDPEPANDTCGFTLFPGAPFNNYMSYTDDECTDNFTPNQVARMHCYLDLVYQQWSESQKPTPIPIPPMVIGQTHKSLTIHWLPPISGVVYDRAPDSMCSACTEDGTFRQYVYKASSGRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPELHLNHMNMTVPCPAEGCSLELLFQYPVQADTLTLWVTYLSMNSSKAFFDIEILLEHKKSMHLGPLNTFCDIPLTIKLHMDEKVMGAKVYTFDERMEIDAALLTSRPNSSLCSGCKPMSYQVLREPPFSSGLPMVVTHPHRKFTDTEVIPGQMYQYQVQAEAVGELGEASPPLSHIHGGPYCGDGKVERSIGEMCDDGDLLNGDGCSRACELEEGFNCAGEPSLCYRYEGDGVCEDFEKESIITDCGLHTPEGYLDQWASQAYSYHEDKEKCPVSLVTGEPHSMICTSWHPDSSPYHSFPGWFPCVFSLKKDQDAGSEQAKDSLQKDNEIWLEVCFNRPGVAVAIYIFLASDGVTPGEHQQATVTLYLIDVSGSNHSLGTYGLSCQQNPLVINVSHHVNVYPQHTSSMLLNFSSPLVGISAVALRTSSQTSSSAPSNCIPEQNYEGKSCAQRPCGEQGRCAPLLLDHTDMVNCTSSSPGHMECAITCQRGYVLQTSSGQYLRNMQKEILLTCSSGHWDKDVICKRLDCGVPDSSLVNYANFSCLEGTDFLKQCSISCVPPAKLQGLNPWLTCLEDGLWSLPEVYCKLECEAPPVIPNANLLLPHFLEGNHDVGTICKYECKPGYYVKETSGSQGKNKFLKIQCLDDGSWEQGSCVPVVCEPPPPVFEGMYECTDGFKLDSQCVLNCNQETEGIPILCTKEGLWTQEFKLCENLQGECPPPTSELNSVEYKCGQGYGIGAVCSPSCVIPPSDPVILPENVTTDTLEHWMEPVKVQSIVCTGRRQWHPDPSLVHCIQSCEPFQADGWCDTINNRAYCNYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ", "length": 1789 }, "evidence": [ { "id": "E1BF00", "url": "https://omabrowser.org/oma/group/E1BF00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1S703-1", "protein_name": "Pappalysin 2", "gene_name": "PAPPA2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMCLKILRISLVILTGWALSTVSSDLGWTRKRSLAQRGHLNLVPPEGERCWLGAKVRRPRAAPQHHLFGVYPSRPGNYLRPYPAGDQGSRHAGRSKLDAEGMAVSSISPDPAGSAGVRREAEWPAAPLVGDGPIGQSELLGDDDTYLGDRGSKKPLGEAGTQECSATAATIVPTFPRPKEPGPKAVRKGRTKSRSRRQVVKGQARGVRGDPSDASWHFRPWSKHPLKHGVRTSPLEGSIQNGGGDPYWEAETVSPQGGLPVLYFSGRRERLLLRPEVLADIPREAFTVEAWVKPEGGQNSPAIIAGVFDNCSHTISDKGWALGIRSGKDVGRRDARFFFSLRTDRVKKATVVMGHSRYQPGKWTHVAVTYDGQRMALYVDGTRVASSPDQSGPLNSPFMASCRSLLLGGDSSEDGHCFRGHLGTLVFWSTARPQSHLQHRPQQPSEVEDLTTLLLTASFEPLEEQWALFGDGKYPRLEVLQGFEPEPEILSPLQPPLCGQTACDNVELISQYNGHWPLRGEKVIRYQVVNICDDEGLNPTVSEEQIRRQHEVLNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGYDGGDCRLQGRCYSWNRRDGLCHTECNNMLNDFDDGDCCDPEAADVRKTCFDPDSPRRAYMSVKELKEALQLNSTHFLNVYFASSVREDLAGAATWPWDKEAISHLGGVVLNPAYYGMPGHTNIMIHEVGHVLGLYHVFKGVSERESCDDPCRETVPSMDTGDLCADTAPTPKSKLCQDPEPTNDTCGFTHFPGAPFSNYMSYTDDDCTDSFTPNQVARMHCYLDLVYQQWSQSRKPTPIPIPPVVIGQTHKSLTIHWLPPISGVVYDRVPGSVCGACTEDGTFRQYVHTASSRRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPELHLYHMNMTVPCPAEGCSLELLFQHPVQADTLTLWVTYLSMDSSQALFDTEILLEHQESVHLGPLDTFCDTPLTIKLHVDGKVLGVKVYTFDERMEIDAALLTSRPHSPLCSGCRPVRYQVLREPPFASGLPVVVTHPDRKFTDMEVIPGQMYRYQVQAEAGAELGEASPPLSHIHGAPYCGDGKVARSLGEECDDGDLLSGDGCSRACELEEGFNCVGEPSLCYVYKGDGICEPFEKETSIADCGLYTPKEHLDQWATQAYSSHEDKKKCPVSLVTGEPHSMICTSYHPDLPEQRPLTGWFPCVTSGNRLQDEGNKQPKGTLERENEVWLKVCFSRPGVATAVFIFLTSDGLVPGEHQRPTVTLHLTDVSGNNHSLGTYELSCQHNPLVINVTHHSNVLFHHATSVLLNFSSPLVGISAVALRTSSHRSPAAPNNCIPDHEGQNHQGQSCVHRPCGEQGSCVPLLLDHADVVNCTSGGPGHMKCAITCQRGFALQTRSGHYLRPIQKEILLTCSSGHWDRAVSCMPLDCGIPDPSLVNYANFSCSEGTDFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEAYCKLECDAPPVIPNANLLLPHCLQGHHDVGSTCRYECKPGYYVVGGADNQVRNKFLKIQCLEGGIWEQGSCLPVVCEPPSPVFEGMYECTNGFELDSQCVLNCNQESKRHPILCTKEGLWTEEFKLCENLQGECPPPTSELNFVEYKCEQGYGIGAVCSPSCVIPPSDPVILPENVTADALEHWMEPVKVQSIVCTGRRQWHPDPLLVNCIQSCEPFQADGWCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ", "length": 1790 }, "evidence": [ { "id": "E1BF00", "url": "https://omabrowser.org/oma/group/E1BF00/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HA04-1", "protein_name": "Pappalysin-2", "gene_name": "Pappa2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMCWKVLRVSLVVLAGWAFSTTSSELGWTRKKFLAQRGQLNQVLLEGEHCWLGIKIRRPRTAPQHHLFGVYPSRPESYLRPYAVGKKRTSYAGASQPGMERQAPSVVPGDLTENPAEVRRESEQPAALWVGDGPIGQSELLRDDDTYLGNGGSKEALGKPATRGSSEAAVSTITTFAYQKRPTEETRRKHQAKSRLPRHVLKRPAEDMTRDPQNAPPDFQLLPKDPLKHGNSDGPLEGTIQNGGGASASGLETFNPQGGLPVLYFSGKRERLLLRPEVLAEIPREAFTVEAWVRSEGGQNNPAIIAGVFDNCSHTANDKGWALGIRSGKEKGRRDARFFFSLRTDRVKKATTVTGHSRYQPGTWAHVAATYDGQHIALYVDGTRVASSPDQSGPLNSPFMSSCRSLLLGGDSSEDGHYFRGYLGTLVIWSTALSQAHLQHSSQHPSRADELSTLILTATFDPLKEQWAPFRDETYPRLEVLQDSDSQPEIRSPLQPPLCGQTACDNVELISQYNEHGPLRGEKVIRYQVVKICDDEGLHPIVSDEQIRRQHDALNKAFSRYNISWQLSVHPVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPAVTDVRKTCFDPDSPKRAYMSVKELKEALQLNSTHFLNVYFASSVGEDLAGAATWPWEKEAVSHLGGVVLNPAYYGMPGHTNTMIHEVGHVLGLYHVFKGVSERESCDDPCRETVPSMETGDLCADTAPTPKSKLCRDPEPANDTCGFIHFPGAPFNNYMSYTDDECTDSFTPNQVARMHCYLDLVYQQWSESRKPTPIPIPPMVIGQTQKSLTIHWLPPISGVVYDRTPGSMCEACTEDGTFHQYVYKASSGRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPELHLYHMNMTVPCPAEGCSLELLFQHPVQADTLTLWVTYLSMNSSKALFDIEILLELKESVHLGPFNTFCDTPLTIKLHVDGKVLGVKVYTFDERMEIDAALLTSRPHSSFCSGCRPVSYRVLREPPFSTGLPMVVTHPHRKFTDMEVTPGQMYKYQVQAEAGGEFGEASPPLSHIHGSPYCGDGKVERSMGETCDDGDLLNGDGCSGVCQLEEGFNCVGEPSLCYRHEGDGICEPFEKETSIIDCGLHAPEGHLDQWATQAYSYHEDKKKCPVSLVTGEPHSMICTSHHPESSPNRLFLGWFPCVFSLKTAPEEGSEKSEDSLQKDNEIWLEVCFDRPGVAEAIFLFLASDGLAPGKRQQSTVTLYLVDVSGSNHSVGTYELSCQHNPLVINVSHHVNVCPHHTSSMLLNFSSPLVGISAVALRTSSHTSSSVTSNCIPEQNHQGQSCAQRPCGEQGRCTPLLLDHADMVNCTSSGPGHMKCAITCQRGYVLQTSSGQYIRTMQKGILLTCSSGHWDKDVSCVHVDCGVPDSSLVNYANFSCLEGTDFQKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPVIPNANLLLPNCLEGNHDVGTICRYECKPGYYVMESTGSQSRNKFLKIQCLDDGTWEQRSCIPVVCEPPSPVFEGMYECTNGFMLDSQCVLNCNQETERTPILCTKEGLWTQEFKLCENLQGECPPPPSELNFVEYKCGQGYGIGAVCSPTCVVPPSDPVMLPENVTTDTLEHWMEPVKVQSIVCTGRRQWHPDPSLVYCIQSCEPFQADGWCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ", "length": 1788 }, "evidence": [ { "id": "E1BF00", "url": "https://omabrowser.org/oma/group/E1BF00/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9BXP8-1", "protein_name": "Pappalysin-2", "gene_name": "PAPPA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMCLKILRISLAILAGWALCSANSELGWTRKKSLVEREHLNQVLLEGERCWLGAKVRRPRASPQHHLFGVYPSRAGNYLRPYPVGEQEIHHTGRSKPDTEGNAVSLVPPDLTENPAGLRGAVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESLGEAGIQKGSAMAATTTTAIFTTLNEPKPETQRRGWAKSRQRRQVWKRRAEDGQGDSGISSHFQPWPKHSLKHRVKKSPPEESNQNGGEGSYREAETFNSQVGLPILYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQNNPAIIAGVFDNCSHTVSDKGWALGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQPGTWTHVAATYDGRHMALYVDGTQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFRGHLGTLVFWSTALPQSHFQHSSQHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEVLQGFEPEPEILSPLQPPLCGQTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNPIVSEEQIRLQHEALNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPDSPKRAYMSVKELKEALQLNSTHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPAYYGMPGHTDTMIHEVGHVLGLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKSELCREPEPTSDTCGFTRFPGAPFTNYMSYTDDNCTDNFTPNQVARMHCYLDLVYQQWTESRKPTPIPIPPMVIGQTNKSLTIHWLPPISGVVYDRASGSLCGACTEDGTFRQYVHTASSRRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPEVHLYHMNMTVPCPTEGCSLELLFQHPVQADTLTLWVTSFFMESSQVLFDTEILLENKESVHLGPLDTFCDIPLTIKLHVDGKVSGVKVYTFDERIEIDAALLTSQPHSPLCSGCRPVRYQVLRDPPFASGLPVVVTHSHRKFTDVEVTPGQMYQYQVLAEAGGELGEASPPLNHIHGAPYCGDGKVSERLGEECDDGDLVSGDGCSKVCELEEGFNCVGEPSLCYMYEGDGICEPFERKTSIVDCGIYTPKGYLDQWATRAYSSHEDKKKCPVSLVTGEPHSLICTSYHPDLPNHRPLTGWFPCVASENETQDDRSEQPEGSLKKEDEVWLKVCFNRPGEARAIFIFLTTDGLVPGEHQQPTVTLYLTDVRGSNHSLGTYGLSCQHNPLIINVTHHQNVLFHHTTSVLLNFSSPRVGISAVALRTSSRIGLSAPSNCISEDEGQNHQGQSCIHRPCGKQDSCPSLLLDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCEQGYGIGAVCSPLCVIPPSDPVMLPENITADTLEHWMEPVKVQSIVCTGRRQWHPDPVLVHCIQSCEPFQADGWCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ", 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"database": "UniProtKB", "id": "E1BF00", "url": "https://www.uniprot.org/uniprotkb/E1BF00" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "E1BF00", "url": "https://www.uniprot.org/uniprotkb/E1BF00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1307, "end_pos": 1309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1325, "end_pos": 1327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1343, "end_pos": 1345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1408, "end_pos": 1410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1694, "end_pos": 1696, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, 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[ "Protein Classification" ] }, { "id": "PF06978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180144", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180144", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BF14", "url": "https://www.uniprot.org/uniprotkb/E1BF14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF14-1", "url": "https://www.uniprot.org/uniprotkb/E1BF14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNAKERKHAKKMRNQPTNVTLSSGFVADSGVKHHNGGGKPFQSQKESHPGTSRQRQTRTTHRPLAESDVKEQPSSRVTFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQTSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLREIAQKEAEKAVHQKKEHSKNKCHKARRCHINRILEFNRRQKKNKWLETHIWHAKRFHMVKRWGYCLGERPTVKSHRACYRAMTSRCLLQDLSYYCCLELEGKEEEILKALSSMCSIDTGLTFAAVHCLSGKCQGSVMLYRANKYPLEMLGPVTFMWKAQGTPGDTSESRQLWIWLHPALKQDILEEIKAVCQCMEPTKATVQIPDPLLTPSQEKSQIDLPEEKVSKKRKRKDDGENAQPVKKVTGDGTRDPLQPYSWLSPATGIVIRDLTMEMNRFRLIGPLSHCILTEALKAASVHSEGEDTEKTPHRWWIETCKNPDSVSLHRRQEAVFELLGGITSPAEIPAGTILGLTVGDPRINLPQKRSKVLPNPEKCQDNEKVRQLLLEGVPVECSHSFLWNQDICKSVTENKISDQDLNRKRSELLVPGSQLFLGPHESKVPILLIQQPGKVTGHEQRGWGSGWDILLPKGWGMAFWIPFIYRGARVGGLKETLVHSQYKRSPNVPDDFPDCPAGVLFAEEQAKHLLEKYKRRPPAKRPNYVKLGTLAPFYCPWEQLTRDWESRVQAPEESSAASSPSGGESGSSRDGVPRVAEPGRTAQLSDDQGTPLCDSSGPEGVMDTDCPATMGTEEATSQSAASSPLCVLRSRRLLRQLSAWCGPRPGGRQATQRAGRGQQGLTGEACPAMLDAFPRALVWVRLALLGKGSPGPHTLICVPAEEDLLQLSRDWLYHGPQEPKHSDPFKSQIREQKEKKKLEKRLNQGRAASEGLAEGGPVAGPQPLTLGLWSGPLPVVTSHCSRVLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSKQPGLDRGLVLLRPPASLQYRFARITIEV", "length": 1015, "header": "tr|E1BF14-1|E1BF14_BOVIN Isoform 1 of POP1 homolog, ribonuclease P/MRP subunit OS=Bos taurus OX=9913 GN=POP1 PE=4 SV=2 CANONICAL=E1BF14-1" }, "isoforms": [ { "isoform_ac": "E1BF14-1", "url": "https://www.uniprot.org/uniprotkb/E1BF14/entry#E1BF14-1", "sequence": { "sequence": "MSNAKERKHAKKMRNQPTNVTLSSGFVADSGVKHHNGGGKPFQSQKESHPGTSRQRQTRTTHRPLAESDVKEQPSSRVTFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQTSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLREIAQKEAEKAVHQKKEHSKNKCHKARRCHINRILEFNRRQKKNKWLETHIWHAKRFHMVKRWGYCLGERPTVKSHRACYRAMTSRCLLQDLSYYCCLELEGKEEEILKALSSMCSIDTGLTFAAVHCLSGKCQGSVMLYRANKYPLEMLGPVTFMWKAQGTPGDTSESRQLWIWLHPALKQDILEEIKAVCQCMEPTKATVQIPDPLLTPSQEKSQIDLPEEKVSKKRKRKDDGENAQPVKKVTGDGTRDPLQPYSWLSPATGIVIRDLTMEMNRFRLIGPLSHCILTEALKAASVHSEGEDTEKTPHRWWIETCKNPDSVSLHRRQEAVFELLGGITSPAEIPAGTILGLTVGDPRINLPQKRSKVLPNPEKCQDNEKVRQLLLEGVPVECSHSFLWNQDICKSVTENKISDQDLNRKRSELLVPGSQLFLGPHESKVPILLIQQPGKVTGHEQRGWGSGWDILLPKGWGMAFWIPFIYRGARVGGLKETLVHSQYKRSPNVPDDFPDCPAGVLFAEEQAKHLLEKYKRRPPAKRPNYVKLGTLAPFYCPWEQLTRDWESRVQAPEESSAASSPSGGESGSSRDGVPRVAEPGRTAQLSDDQGTPLCDSSGPEGVMDTDCPATMGTEEATSQSAASSPLCVLRSRRLLRQLSAWCGPRPGGRQATQRAGRGQQGLTGEACPAMLDAFPRALVWVRLALLGKGSPGPHTLICVPAEEDLLQLSRDWLYHGPQEPKHSDPFKSQIREQKEKKKLEKRLNQGRAASEGLAEGGPVAGPQPLTLGLWSGPLPVVTSHCSRVLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSKQPGLDRGLVLLRPPASLQYRFARITIEV", "length": 1015, "header": "tr|E1BF14-1|E1BF14_BOVIN Isoform 1 of POP1 homolog, ribonuclease P/MRP subunit OS=Bos taurus OX=9913 GN=POP1 PE=4 SV=2 CANONICAL=E1BF14-1" }, "locus": { "chromosome": "14", "start_pos": 66115081, "end_pos": 66086401, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016721.7", "url": "https://www.ensembl.org/id/ENSBTAT00000016721.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016721.5", "url": "https://www.ensembl.org/id/ENSBTAP00000016721.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511306", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511306", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YEA9-1", "protein_name": "POP1 homolog, ribonuclease P/MRP subunit", "gene_name": "POP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAAREKKRARKMRNQPASVTLPAEPGSFPGGGGGSGRACSAPGDVRSEQQYQQQRFLHQSVGPPYRKDQNRGDSRGRGRGGWQGEHQSSSEEMPRYITVSTFAQARAAEIKAMLKAVAQKSSNSLVFQTLPRHVRRRAMSHNIKRLPRRLQEVARKEAEKAVHQKKEQSKTKCRKARRRHVNLVAEFNCRQRKNIWLETHIWHAKRFHMVKKWGYCLGNSPTEKCYRACYRAMTNHCLLQDLSYYCCLELTGKENELLKQLARICSVDAGLTFGAANCLSGRFQGSLNLYRADHYPEEMLGPVTFIWKPKHGSENRQLWIWMHPALKQDILNELKAIFQCSEPQEVCIPEPITTLNQEEKQMDVVQRLGKKRKKEDKEGDKAVPVKKIIGDGTRDPLQSYSWVSQTTGIVISDRTMEILRYRLIGPLSHSVLTETLKAASIQTEMVDSESKLNNWWVENCKDSEKVSLHHRQTAIFELLEGISSPSAMPPGTILGLTVGDPRVNLPKKKTKAMPDPEKYQDNDKVRQLYLEGVPVECAHSFIWDQDICKNVTENKISEQELNKMRAQLLVPGSQLDLGPCESKIPILLVQQPGKMAGEDRPGWGSGWDIYLPKGWGMAFWIPFIYRGVRVGGLQEASKHSEYQRTPHTPDDFPDCPAGMQFAQELESSLLDKFKRRPPAKRANYIKLGTLSPFICPWGQLVKSWEGRMKASEEFVCPSSPHAEHCATEGHGFCDPKAEAEKEASPENGEVEETMEISSEDAMKTEGDPGTQDFGERGETMRSDFIVLRSEKLLMQLSAWCYPTCGKDRRPRLVSRLGGKEMTEEVLLPILMSYPRALVWVNLSLLRKGNPELHAMICIPTEDDLVHLSKDRLFCGPQEPKHRDVFKHKVQKLKEIKRKKKEEYNVKAQESNPPSVPEKETTEECKDLILGLWSGTLPDVISHCSRTLLGYVTRGDFSLATGCGEALGFVSLTGLLYMLHSQPADKKGIVLLRTPASLQYRFARLSIEV", "length": 1009 }, "evidence": [ { "id": "E1BF14", "url": "https://omabrowser.org/oma/group/E1BF14/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4AE75-1", "protein_name": "POP1 homolog, ribonuclease P/MRP subunit", "gene_name": "Pop1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNAKERKHAKKMRSQPSNVTLSSGFVTERDGKRHFGGKPSQSQKQELHSGTSRQWQIKMSPHLLPESDANEQTSSKTMFKKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEMAKKEAEKAAHQKKEHSKNKCHKARRCHINRTLEFNRRQQKNIWLETHIWHAKRFHMVKRWGYCLGERPTAKSHRACYRAMTDLCLLQDLSYYCCLELKGKEEEILKALSQMCSIDTGLTFAAVHCLSGKRQGSLMLYRANKYPRDMLGPVTFIWKSRETPGDASEERQLWIWLHPTLKLAVLEEIKTTCQCSEPVKPSVCVPAPLLTPAQEDIQAGLADDKIGKKRKRRDDGENARRAKKTIGDGTGDPCQPRSWLSPTTGIVVSDLTMEMNRFRLVGPLSHCILTSALRAAPVHRGEEDAEETPHGWWTDTCRSPHGLSLHQRQEAVFQLLGGISSPAEIPAGTILGLTVRDPRVNLPPQRCRALPDPERYHVSEFICEEGMCTSSWSCAHWKPLSDHTDDPDNEQVKQLLLEGVPVECAHSFIWNQDICQSVTENKIVDQDLNRMRSELLVPGSQLVLGARESKIPILLIQQPGKVTGEDRLGWGSGWDILLPKGWGMAFWIPFIYRGARVGGLKEAAVHSQYKRSPNVPGDFPDCRAGVLFAEDQAKDLLEKYQRRPPAKRPNYVKLGTLAPFCCPWEQLTRDWESRIQTQEAAVIDSVPGAQETDPRRLGVPCVPKETCQLSNEASIAENQPRKPEVTGCQAQAGTEVALEQNASEDHAAATGSQLCVVRSRKLLKQLSSWCGPSSEVRRAPCRGQQELTRKACLSILADFPRALVWVSLSLLKKGSPEPHTMICVPSKEDLFQLSQDQCYHGPCESRHSDPFKSLILKEKEKKKKEKRQDGEQGASKGQAAGAPTAGQEARIQGLWSGPLPGLTSHCSRPLLGFVTHGDFSMAVGCGEALGFVSVTGLLEMLSSQSAAMRGLVLLRPPTSLQYRFARVTIEV", "length": 1044 }, "evidence": [ { "id": "E1BF14", "url": "https://omabrowser.org/oma/group/E1BF14/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S0M3-1", "protein_name": "POP1 homolog, ribonuclease P/MRP subunit", "gene_name": "POP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNAKERKHAKKMRNQPTNVTLSSGFVADGGVKHHSGGGKPFQAQKDPHSGTSRQWHARTSHHALAESDAKEQSSSKVTFRKKGGWKAGPEGTSQDIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKTKCHKARRCHMNRMLEFNRRQKKNIWLETHIWHAKRFHMVKRWGYCLGERPTAKSHRACYRAMTSRCLLQDLSYYCCLELKGKEEEILKALSPMCSIDTGLTFAAVHCLSGKRQGSLMLYRANKYPQEMLGPVTFIWKPQGTPADTSESRQLWIWLHPTLKQDILEEIKAACQCMEPTKSAVCIPDSLLTPSQEKGQTEKIGRKRKWEDDGENAEPIKKIIGDGTRDPLQPYSWLSPTTGIMISDFTMEMNRFRLIGPLSHAILTEALKAASVHTEGEDTEKTPHRWWIETCKNPDSVSLHHRQEGIFGLLGGITSPAEIPAGTVLGLTVGDPRINLPQKRSRVLPNPEKCQDNEKVRQLLLEGVPVECSHSFLWNPDICKSVTENKISDQDLNRKRSELLVPGSQLLLGPHESKVPILLIQQPGKATGDDQRGWGSGWDVLLPKGWGMAFWIPFIYRGARVGGLKETVMHSQYKGSPNVPGDFPDCPAGVQFAQEQAKNLLEKYTRRPPAKRPNYVKLGTLAPFCCPWEQLTRDWESRVQAREESPAIPSPGGEESGPRRDVVPCAPTAQRTLQLSDDAGTSLNDADMMDTDCPAPAGTKWVAGRGAPRSLLCVVRSRKLLRQLSAWCGDSRAAQRAPGRGQQDLTREACLSISDRFPRALVWVRLSLLSKGSPEPHTMICVPAEEDLLQLSRDRLYRGPQESKHSDPFKSKIRKQKEQKKREKRQSPGPAAAEGLAEGDPPGHQALTLGLWSGPLPVVTSHCSRVLLGFVTQGDFSMAVGCGAALGFVSLTGLLDMLSSQPGAERGLVLLRPPASLQYRFARIAIEV", "length": 1003 }, "evidence": [ { "id": "E1BF14", "url": "https://omabrowser.org/oma/group/E1BF14/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q99575-1", "protein_name": "Ribonucleases P/MRP protein subunit POP1", "gene_name": "POP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNRCLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSESRQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQDNEKVRQLLLEGVPVECTHSFIWNQDICKSVTENKISDQDLNRMRSELLVPGSQLILGPHESKIPILLIQQPGKVTGEDRLGWGSGWDVLLPKGWGMAFWIPFIYRGVRVGGLKESAVHSQYKRSPNVPGDFPDCPAGMLFAEEQAKNLLEKYKRRPPAKRPNYVKLGTLAPFCCPWEQLTQDWESRVQAYEEPSVASSPNGKESDLRRSEVPCAPMPKKTHQPSDEVGTSIEHPREAEEVMDAGCQESAGPERITDQEASENHVAATGSHLCVLRSRKLLKQLSAWCGPSSEDSRGGRRAPGRGQQGLTREACLSILGHFPRALVWVSLSLLSKGSPEPHTMICVPAKEDFLQLHEDWHYCGPQESKHSDPFRSKILKQKEKKKREKRQKPGRASSDGPAGEEPVAGQEALTLGLWSGPLPRVTLHCSRTLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSSQPAAQRGLVLLRPPASLQYRFARIAIEV", "length": 1024 }, "evidence": [ { "id": "E1BF14", "url": "https://omabrowser.org/oma/group/E1BF14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "E1BF14", "url": "https://www.uniprot.org/uniprotkb/E1BF14" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "E1BF14", "url": "https://www.uniprot.org/uniprotkb/E1BF14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA decay", "id": "GO:0016078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016078", "evidence": [ { "database": "UniProtKB", "id": "E1BF14", "url": "https://www.uniprot.org/uniprotkb/E1BF14" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "E1BF14", "url": "https://www.uniprot.org/uniprotkb/E1BF14" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "E1BF14", "url": "https://www.uniprot.org/uniprotkb/E1BF14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "E1BF14", "url": "https://www.uniprot.org/uniprotkb/E1BF14" } ], "pmid": "" }, { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "E1BF14", "url": "https://www.uniprot.org/uniprotkb/E1BF14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BF14-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1015, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BF14-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BF14" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF14" }, { "id": "PF22770", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22770" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POP1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 846, "end_pos": 1015, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF14" }, { "id": "PF08170", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08170" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POPLD", "eco_id": "ECO_0000259", "start_pos": 616, "end_pos": 707, "start_aa": "Gly", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF14" }, { "id": "PF06978", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06978" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pop1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 168, "end_pos": 256, "start_aa": "Gln", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"MEPGEPREPREPGPGAETAAAPQWEEAKTFYDNLAPQKKPKSPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNRRLRELYPESEDLFDIVLVTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVQEAIDEGIAAATIFSPSRDVAVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTSRRTSPTKQAAPAQ", "length": 365, "header": "tr|E1BF39-1|E1BF39_BOVIN Isoform 1 of 5'-nucleotidase, cytosolic IA OS=Bos taurus OX=9913 GN=NT5C1A PE=4 SV=1 CANONICAL=E1BF39-1" }, "isoforms": [ { "isoform_ac": "E1BF39-1", "url": "https://www.uniprot.org/uniprotkb/E1BF39/entry#E1BF39-1", "sequence": { "sequence": "MEPGEPREPREPGPGAETAAAPQWEEAKTFYDNLAPQKKPKSPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNRRLRELYPESEDLFDIVLVTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVQEAIDEGIAAATIFSPSRDVAVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTSRRTSPTKQAAPAQ", "length": 365, "header": "tr|E1BF39-1|E1BF39_BOVIN Isoform 1 of 5'-nucleotidase, cytosolic IA OS=Bos taurus OX=9913 GN=NT5C1A PE=4 SV=1 CANONICAL=E1BF39-1" }, "locus": { "chromosome": "3", "start_pos": 106418951, "end_pos": 106403711, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003884.5", "url": "https://www.ensembl.org/id/ENSBTAT00000003884.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003884.4", "url": "https://www.ensembl.org/id/ENSBTAP00000003884.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:504454", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504454", "resource": "KEGG Pathway" }, { "id": "R-BTA-73621", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73621", "resource": "Reactome", "description": "Pyrimidine catabolism" }, { "id": "R-BTA-74259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-74259", "resource": "Reactome", "description": "Purine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZYY7-1", "protein_name": "5'-nucleotidase, cytosolic IA", "gene_name": "Nt5c1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGRLGRAGGAGSLALPPGPAACLSHPGRASLPRLSSLSSLSPTLSSPARPDRIRAGTWNQGSPRRPENPDQGQRPPRCRAGRKPRRSMTISRPRRNPNRPWLILVTEIVSCGLPVSGVWSVPTEAPEMVDSQPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNKQLRELYPDSEDIFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSKDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQNPRREKQSLGAQ", "length": 454 }, "evidence": [ { "id": "E1BF39", "url": "https://omabrowser.org/oma/group/E1BF39/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZCP6-1", "protein_name": "5'-nucleotidase, cytosolic IA", "gene_name": "NT5C1A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLCPHSPWRSVCRISALPVLPQPCSASWGRSAIRFVTLQQCGKCPPASLVSQCRAERAHCWELLPPCVRVHYLSLHPHALSCSSRCLLFWVSVAAGILGMFQLRRGSVPDPGPKPENAITIAVSSRALFRMEEEQKIYNEQGVEAYVKYQLDHENEPFLPGAAFPFVKALEAVNTQLRELYPDSEELFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPIGYLKAYHTNLYLSSDAEKVSGAIEEGIAAATIFSPSKDLEVSEKQLRVAFDGDAVLFSDESEQIVKAHGLDMFFEHEKAHENNPLAQGPLKGFLEALGKLQKKFYSKGLRMECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLKKIRPHIFFDDQMFHVEGAKEMGTVAAHVPYGVAQKHKRPLQEKQPQNSK", "length": 435 }, "evidence": [ { "id": "E1BF39", "url": "https://omabrowser.org/oma/group/E1BF39/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A3KFX0-1", "protein_name": "Cytosolic 5'-nucleotidase 1A", "gene_name": "Nt5c1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGQPREAREPGPGAETAAVPRWEEAKTFYDNLSSKKKPKSPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNKRLRELYPDSEDIFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADADKVREAIDEGIAAATIFSPSRDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQNPRRAAAAKQSLGAQ", "length": 365 }, "evidence": [ { "id": "E1BF39", "url": "https://omabrowser.org/oma/group/E1BF39/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1SV04-1", "protein_name": "5'-nucleotidase, cytosolic IA", "gene_name": "NT5C1A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPEEPRELREPGPGAETAAAPRWEEAKTFYDNLTSKKKPKSPKPQNAVTIAVSSRALFRMDEEQRIYMEQGVEEYVRYQLEHENEPFSPGPISSPIQALEAVNKRLRELYPESEDLFDIVLVTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVQEAIDEGIAAATIFSPSRDVAVSQSQLRVAFDGDAVLFSDESERIVKAHGLDSFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTPRRTTPTKQAPSAQ", "length": 365 }, "evidence": [ { "id": "E1BF39", "url": "https://omabrowser.org/oma/group/E1BF39/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9BXI3-1", "protein_name": "Cytosolic 5'-nucleotidase 1A", "gene_name": "NT5C1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPGQPREPQEPREPGPGAETAAAPVWEEAKIFYDNLAPKKKPKSPKPQNAVTIAVSSRALFRMDEEQQIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNRRLRELYPDSEDVFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSRDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTPRRTAPAKQAPSAQ", "length": 368 }, "evidence": [ { "id": "E1BF39", "url": "https://omabrowser.org/oma/group/E1BF39/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "E1BF39", "url": "https://www.uniprot.org/uniprotkb/E1BF39" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "E1BF39", "url": "https://www.uniprot.org/uniprotkb/E1BF39" } ], "pmid": "" }, { "name": "5'-nucleotidase activity", "id": "GO:0008253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008253", "evidence": [ { "database": "UniProtKB", "id": "E1BF39", "url": "https://www.uniprot.org/uniprotkb/E1BF39" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BF39", "url": "https://www.uniprot.org/uniprotkb/E1BF39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "adenosine metabolic process", "id": "GO:0046085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046085", "evidence": [ { "database": "UniProtKB", "id": "E1BF39", "url": "https://www.uniprot.org/uniprotkb/E1BF39" } ], "pmid": "" }, { "name": "AMP catabolic process", "id": "GO:0006196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006196", "evidence": [ { "database": "UniProtKB", "id": "E1BF39", "url": "https://www.uniprot.org/uniprotkb/E1BF39" } ], "pmid": "" }, { "name": "allantoin metabolic process", "id": "GO:0000255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000255", "evidence": [ { "database": "UniProtKB", "id": "E1BF39", "url": "https://www.uniprot.org/uniprotkb/E1BF39" } ], "pmid": "" }, { "name": "dAMP catabolic process", "id": "GO:0046059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046059", "evidence": [ { "database": "UniProtKB", "id": "E1BF39", "url": "https://www.uniprot.org/uniprotkb/E1BF39" } ], "pmid": "" }, { "name": "IMP catabolic process", "id": "GO:0006204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006204", "evidence": [ { "database": "UniProtKB", "id": "E1BF39", "url": "https://www.uniprot.org/uniprotkb/E1BF39" } ], "pmid": "" }, { "name": "dGMP catabolic process", "id": "GO:0046055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046055", "evidence": [ { "database": "UniProtKB", "id": "E1BF39", "url": "https://www.uniprot.org/uniprotkb/E1BF39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BF39-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 365, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BF39-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BF39" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BF52-1", "uniprot_ac": "E1BF52", "uniprot_id": "E1BF52_BOVIN", "mass": { "chemical_mass": 38973.0, "monoisotopic_mass": 38973.0 }, "refseq": {}, "gene_names": [ { "name": "GFER", "type": "recommended", "evidence": [ { "id": "E1BF52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF52" } ] } ], "protein_names": [ { "name": "Sulfhydryl oxidase", "type": "recommended", "evidence": [ { "id": "E1BF52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF52/entry#names_and_taxonomy" } ] }, { "name": "1.8.3.2", "type": "synonym", "evidence": [ { "id": "E1BF52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF52/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BF52", "url": "https://www.uniprot.org/uniprotkb/E1BF52" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GFER", "url": "https://www.uniprot.org/uniprotkb/E1BF52", "locus": { "chromosome": "25", "start_pos": 1542223, "end_pos": 1539265, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017631", "url": "https://www.ensembl.org/id/ENSBTAG00000017631" } ] } } ], "crossref": [ { "id": "E1BF52", "url": "https://alphafold.ebi.ac.uk/entry/E1BF52", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017631", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017631", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR017905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BF52", "url": "https://www.orthodb.org/?gene=E1BF52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12645", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12645", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12645:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12645:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17357", "url": "https://www.rhea-db.org/rhea/17357", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "59116", "url": "https://www.rhea-db.org/rhea/59116", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BF52", "url": "https://www.uniprot.org/uniprotkb/E1BF52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF52-1", "url": "https://www.uniprot.org/uniprotkb/E1BF52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGASRAATRRSKRPQPEAASRPRRVVHNTLIFYWRKREHCHGRHKTGSGRGRRPRGKARTRGSRTARTAARASGASPARTPASPGARTLAASPAPAPGPAPGPSSAPAARAPGSCGRALAAARALAWRPAWMPVWRPRWPGRHCAGGMAAPGERGRFGAGILFSFLPGGARSEVTDDLVTDARGRGAGRREATASARAPSAGPASDPPVSEFSPRRPCRACVDFKSWMRTQQKRDSKFREDCPQDREELGRNSWAVLHTLAAYYPDLPTPEQQQDMAQFIHLFSKFYPCEECAEDIRKRIYRDQPDTRTRVSFTQWLCRLHNEVNRKLGKPDFDCSLVDERWRDGWKDGSCD", "length": 352, "header": "tr|E1BF52-1|E1BF52_BOVIN Isoform 1 of Sulfhydryl oxidase OS=Bos taurus OX=9913 GN=GFER PE=4 SV=3 CANONICAL=E1BF52-1" }, "isoforms": [ { "isoform_ac": "E1BF52-1", "url": "https://www.uniprot.org/uniprotkb/E1BF52/entry#E1BF52-1", "sequence": { "sequence": "MGASRAATRRSKRPQPEAASRPRRVVHNTLIFYWRKREHCHGRHKTGSGRGRRPRGKARTRGSRTARTAARASGASPARTPASPGARTLAASPAPAPGPAPGPSSAPAARAPGSCGRALAAARALAWRPAWMPVWRPRWPGRHCAGGMAAPGERGRFGAGILFSFLPGGARSEVTDDLVTDARGRGAGRREATASARAPSAGPASDPPVSEFSPRRPCRACVDFKSWMRTQQKRDSKFREDCPQDREELGRNSWAVLHTLAAYYPDLPTPEQQQDMAQFIHLFSKFYPCEECAEDIRKRIYRDQPDTRTRVSFTQWLCRLHNEVNRKLGKPDFDCSLVDERWRDGWKDGSCD", "length": 352, "header": "tr|E1BF52-1|E1BF52_BOVIN Isoform 1 of Sulfhydryl oxidase OS=Bos taurus OX=9913 GN=GFER PE=4 SV=3 CANONICAL=E1BF52-1" }, "locus": { "chromosome": "25", "start_pos": 1541691, "end_pos": 1539464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023446.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023446.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023446.7", "url": "https://www.ensembl.org/id/ENSBTAP00000023446.7" } ] } } ], "glycosylation": [], "phosphorylation": [], 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BF61-1", "uniprot_ac": "E1BF61", "uniprot_id": "E1BF61_BOVIN", "mass": { "chemical_mass": 35904.0, "monoisotopic_mass": 35904.0 }, "refseq": { "ac": "NP_001377463", "name": "olfactory receptor family 6 subfamily C member 1", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377463", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377463" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BF61", "url": "https://www.uniprot.org/uniprotkb/E1BF61#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BF61", "url": "https://www.uniprot.org/uniprotkb/E1BF61" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR6C1", "url": "https://www.uniprot.org/uniprotkb/E1BF61", "locus": { "chromosome": "5", "start_pos": 58757261, "end_pos": 58758202, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024691", "url": "https://www.ensembl.org/id/ENSBTAG00000024691" } ] } } ], "crossref": [ { "id": "E1BF61", "url": "https://alphafold.ebi.ac.uk/entry/E1BF61", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "788009", "url": "https://www.ncbi.nlm.nih.gov/gene/788009", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"https://www.uniprot.org/uniprotkb/E1BF61/entry#E1BF61-1", "sequence": { "sequence": "MRNHTETIEFILLGLSDNPQLQVVIFVFLLITYMLSITGNLTIITLTLLDAHLQTPMYFFLRNFSILEVSFTTVSIPKFLATIITGDKTISFNDCIAQLFFFILLGVTEFYLLSAMSYDRYIAICKPLRYMTIMNHRVCTLLVFSSWLVSFLIIFPALMLLLNLDYCRSNIIDHFTCDYFPLLQLSCSDTNFLEMMGFSCAVFTLMFTLALIILSYTYIIRTILRIPSTSQRTKAFSTCSSHMIVISISYGSCIFMYIKPSAQDRVSLSKGVAVLNTSVAPMLNPFIYSLRNQQVKQAFKDMARKTIFQKQMK", "length": 313, "header": "tr|E1BF61-1|E1BF61_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR6C1 PE=3 SV=3 CANONICAL=E1BF61-1" }, "locus": { "chromosome": "5", "start_pos": 58758202, "end_pos": 58757264, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015822.6", "url": "https://www.ensembl.org/id/ENSBTAT00000015822.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015822.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015822.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:788009", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788009", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BQ80-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100736743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNYTVVTEFILLGLSDDPQLQVVVFVFLLITYLLSITGNLTIITLTLLDPHLQTPMYFFLRNFSLLEVSFTTVTIPRFLSTIISGDKTISFNDCMAQLFFFILLGVAEFYLLAAMSYDRYVAICKPLHYLAIMNQRVCVLLVFSSWLVSFLIIFPSLMLLLNLDYCKSNIIDHFTCDYFPLLQLSCSDTTFLEMVGFSCAVFTLMFTLALIFLSYIYIIRTIVRIPSTSQRTKAFSTCSSHMIVISISYGSCIFMYIKPSAKDRVSLSKGVAVLNTSVAPMLNPFIYSLRNQQVKRAFMDMARKVAFFSRK", "length": 312 }, "evidence": [ { "id": "E1BF61", "url": "https://omabrowser.org/oma/group/E1BF61/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8J8XG97-1", "protein_name": "Olfactory receptor", "gene_name": "Or6c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNHTETTVFILLGLSDDPKLQVVIFIFLFITYTLSITGNVTIITLTLVDSHLQTPMYFFLRNFSVLEVSFITVTIPKFLGTIISGDKTISFNNCIAQLFFFILLGVTEFYLLAAMSYDRYIAICKPLHYLTIMSQNVCTMLVFASWLVSFLIIFPALMLLLQLDYCGSNVIDHYTCDYFPLLQLSCSDTKFLERMGFSCAVFTLMFTLVLIFLSYTHIIRTIVKIPSASQRSKAFSTCSSHMIVISISYGSCIFMYIKPSAADRASLTKGVAILNTSVAPMLNPFIYSLRNQQVRRAFMSMVRKMVFFQKYMK", "length": 314 }, "evidence": [ { "id": "E1BF61", "url": "https://omabrowser.org/oma/group/E1BF61/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3ICE9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100772303", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRNRTETTEFILLGLSDDPKLQVVIFVFLFITYTLSITGNLTIITLTLLDSQLQTPMYFFLRNFSVLEVSFTTVTIPKFLGNIISGDKTISFNNCIAQLFFFILLGVTEFYLLAAMSYDRYVAICKPLHYLTIMSQKVCTMLVFACWLVSFLIIFPALMLLLQLDYCGSNIIDHYTCDYFPLLQISCSDTNFLEKMGFSCAVFTLMFTLALIFLSYTYIIRTIVKIPSASQRTKAFSTCSSHMIVISISYGSCIFMYIKPSASDRASLTKGVAVLNTSVAPMLNPFIYSLRNQQVKQAFLNMARKMVFFTGNVK", "length": 314 }, "evidence": [ { "id": "E1BF61", "url": "https://omabrowser.org/oma/group/E1BF61/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8VGJ2-1", "protein_name": "Olfactory receptor", "gene_name": "Or6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNHTETTEFILLGLSDDPKLQVVIFVFLFITYTLSITGNLTIITLTLLDSHLQTPMYFFLRNFSVLEVSFTTVTIPKFLGTIISGDKTISFNNCIAQLFFFILLGVTEFYLLAAMSYDRYVAICKPLHYLTIMSQKVCTMLVFASWLTSFLIIFPALMLLLQLDYCGSNIIDHYTCDYFPLLQLSCSDTKFLERMGFSCAVFTLMLTLVLIFLSYTYIIKTIVKIPSASQRSKAFSTCSSHMIVISISYGSCIFMYIKPSATDRASLTKGVAILNTSVAPMLNPFIYSLRNQQVKQAFMNMTRKIVFSTSK", "length": 312 }, "evidence": [ { "id": "E1BF61", "url": "https://omabrowser.org/oma/group/E1BF61/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96RD1-1", "protein_name": "Olfactory receptor 6C1", "gene_name": "OR6C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRNHTEITEFILLGLTDDPNFQVVIFVFLLITYMLSITGNLTLITITLLDSHLQTPMYFFLRNFSILEISFTTVSIPKFLGNIISGDKTISFNNCIVQLFFFILLGVTEFYLLAAMSYDRYVAICKPLHCLSIMNRRVCTLLVFTSWLVSFLIIFPALMLLLKLHYCRSNIIDHFTCDYFPLLQLACSDTKFLEVMGFSCAAFTLMFTLALIFLSYIYIIRTILRIPSTSQRTKAFSTCSSHMVVVSISYGSCIFMYIKPSAKDRVSLSKGVAILNTSVAPMMNPFIYSLRNQQVKQAFINMARKTVFFTST", "length": 312 }, "evidence": [ { "id": "E1BF61", "url": "https://omabrowser.org/oma/group/E1BF61/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BF61", "url": "https://www.uniprot.org/uniprotkb/E1BF61" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "E1BF61", "url": "https://www.uniprot.org/uniprotkb/E1BF61" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BF61", "url": "https://www.uniprot.org/uniprotkb/E1BF61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BF61-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BF61-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BF61" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF61" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 276, "end_pos": 278 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BF75-1", "uniprot_ac": "E1BF75", "uniprot_id": "E1BF75_BOVIN", "mass": { "chemical_mass": 94848.0, "monoisotopic_mass": 94848.0 }, "refseq": { "ac": "XP_024840366", "name": "N-acetyltransferase ESCO1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840366" }, "gene_names": [ { "name": "ESCO1", "type": "recommended", "evidence": [ { "id": "E1BF75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF75" } ] }, { "name": "ESCO1", "type": "synonym", "evidence": [ { "id": "XP_024840366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840366" } ] } ], "protein_names": [ { "name": "Establishment of sister chromatid cohesion N-acetyltransferase 1", "type": "synonym", "evidence": [ { "id": "E1BF75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF75/entry#names_and_taxonomy" } ] }, { "name": "N-acetyltransferase ESCO1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024840366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840366" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BF75", "url": "https://www.uniprot.org/uniprotkb/E1BF75" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ESCO1", "url": "https://www.uniprot.org/uniprotkb/E1BF75", "locus": { "chromosome": "24", "start_pos": 34670611, "end_pos": 34643555, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017597", "url": "https://www.ensembl.org/id/ENSBTAG00000017597" } ] } } ], "crossref": [ { "id": "E1BF75", "url": "https://alphafold.ebi.ac.uk/entry/E1BF75", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017597", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017597", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "535035", "url": "https://www.ncbi.nlm.nih.gov/gene/535035", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:535035", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535035", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEHCNST", "url": "https://omabrowser.org/oma/group/KEHCNST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BF75", "url": "https://www.orthodb.org/?gene=E1BF75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45884:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45884:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2468052", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2468052", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024840366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840366", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "45948", "url": "https://www.rhea-db.org/rhea/45948", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NZU7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZU7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF75", "url": "https://www.uniprot.org/uniprotkb/E1BF75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF75-1", "url": "https://www.uniprot.org/uniprotkb/E1BF75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSIQEKSKENSSSVIKKNEDKNLETQVQGSQKNLAKKSDPKEAIKSLVKSSNESKVNQPELGTCMSTRSASTDKRASKSTNKNMVTVKGHSQQESTKQKKISQKKTVHETPKSSEQLNRRSQRLQQLTEVSTRSLRSREIQGQAQAVKQSLPPTKKEHCNNTQSKSNKAKTNQKHVKRKVLEIKSDSKEEENSVTNEAINSPKGKKRKVEHQTAYTSGSQCIKGSEKCLENTRKEETKSSSEIKRSKVATSVVSKKNEMKKSVHTQVNNSAKSQKSPQPSVPEQTGDNGLEQAGTSKRGSILQLCEEIAGEIESDTVEVKKESSQMESVKEEKPTEIKLEETETERQILHQKEANQDVQCNRFFPSRKTKPVKCILNGINNSTKKNSNWTKIKLSKFNSVQQNKLDSQFSPKSGLLRTSFSLPALETHQQVTQSTFLGSKPYGDKNKACQQEEMKEVNSEDVTPNDITVEMNKIPKKAPENCHLGNQIKPPPDQPLDKQKKDAFESTPDKNCSLCLESKLENNPVENATTVSTLLSQAKIDTGENKFPGSIPKQHSVLCNQTSKTSDNREIPPNHSWPKCNSHLEITIPKDLKLKEAEKADEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST", "length": 841, "header": "tr|E1BF75-1|E1BF75_BOVIN Isoform 1 of Establishment of sister chromatid cohesion N-acetyltransferase 1 OS=Bos taurus OX=9913 GN=ESCO1 PE=3 SV=1 CANONICAL=E1BF75-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NZU7-1", "url": "https://www.uniprot.org/uniprotkb/E1BF75/entry#A0ABI0NZU7-1", "sequence": { "sequence": "MVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST", "length": 172, "header": "tr|A0ABI0NZU7-1|A0ABI0NZU7_BOVIN Computationally mapped isoform of Establishment of sister chromatid cohesion N-acetyltransferase 1 OS=Bos taurus OX=9913 GN=ESCO1 PE=4 SV=1 CANONICAL=E1BF75-1" }, "locus": { "chromosome": "24", "start_pos": 34669607, "end_pos": 34662918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144448.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144448.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104395.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104395.1" } ] } }, { "isoform_ac": "E1BF75-1", "url": "https://www.uniprot.org/uniprotkb/E1BF75/entry#E1BF75-1", "sequence": { "sequence": "MMSIQEKSKENSSSVIKKNEDKNLETQVQGSQKNLAKKSDPKEAIKSLVKSSNESKVNQPELGTCMSTRSASTDKRASKSTNKNMVTVKGHSQQESTKQKKISQKKTVHETPKSSEQLNRRSQRLQQLTEVSTRSLRSREIQGQAQAVKQSLPPTKKEHCNNTQSKSNKAKTNQKHVKRKVLEIKSDSKEEENSVTNEAINSPKGKKRKVEHQTAYTSGSQCIKGSEKCLENTRKEETKSSSEIKRSKVATSVVSKKNEMKKSVHTQVNNSAKSQKSPQPSVPEQTGDNGLEQAGTSKRGSILQLCEEIAGEIESDTVEVKKESSQMESVKEEKPTEIKLEETETERQILHQKEANQDVQCNRFFPSRKTKPVKCILNGINNSTKKNSNWTKIKLSKFNSVQQNKLDSQFSPKSGLLRTSFSLPALETHQQVTQSTFLGSKPYGDKNKACQQEEMKEVNSEDVTPNDITVEMNKIPKKAPENCHLGNQIKPPPDQPLDKQKKDAFESTPDKNCSLCLESKLENNPVENATTVSTLLSQAKIDTGENKFPGSIPKQHSVLCNQTSKTSDNREIPPNHSWPKCNSHLEITIPKDLKLKEAEKADEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST", "length": 841, "header": "tr|E1BF75-1|E1BF75_BOVIN Isoform 1 of Establishment of sister chromatid cohesion N-acetyltransferase 1 OS=Bos taurus OX=9913 GN=ESCO1 PE=3 SV=1 CANONICAL=E1BF75-1" }, "locus": { "chromosome": "24", "start_pos": 34669607, "end_pos": 34643754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031059.6", "url": "https://www.ensembl.org/id/ENSBTAT00000031059.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000031022.3", "url": "https://www.ensembl.org/id/ENSBTAP00000031022.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:535035", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535035", "resource": "KEGG Pathway" }, { "id": "R-BTA-2468052", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2468052", "resource": "Reactome", "description": "Establishment of Sister Chromatid Cohesion" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B1A4-1", "protein_name": "Establishment of sister chromatid cohesion N-acetyltransferase 1", "gene_name": "ESCO1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMSIQEKSKENSSSAITKSEDKNLETQIQDSQKTPAKKPGPKEAVKSLVNSSNKSRTNQSELGTCMSTRSASSDKKPGKSINKNMVTVKGHSQQESIKKKLSQKKSVHETPKSHEQLNRRSQRLQQLTEVSTRSLRSREIHGQVQAAKQSLPSTRKEHCSNTQSKSNKVKTNQKHVKRKVLEINSDSKEDENSVMNEVINSPKGKKRKIEPQTAYTCSSQCIKESEKCLQKNTRKEETKSVPVTTSEIKRSKKATSVVSKKNEMKKSVHTQVNTSAKPQKSPQPSVPEQSVDNELEQAGKSKRGSILQLCEEIAGEIESDTVEVKKESSQMENIKEEKPTEIKLEETDTERQILHQKETNQDVQCNRFFPSRKTRPVKCILNGINSSTKKNSNWTKIKLSKFNSAQQNKLDTQVSPKLGLLRTNFSLPPLEMHHPVTQSTFLGSKSYDDKKKACQQEEMKEINSEEVNDITVEINKTTKRAPENCHLDNQIKPPPDQPLDNQKKDSFESTPDKNCSLCLESNLGNNPVENTSSVSTLLSQANVDTGENKFPGSAPKQHSIFNNQTSKTSDNRGTPPNHSWPKCNSHLEIRIPRDLKLKEAEKADEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRRKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST", "length": 843 }, "evidence": [ { "id": "E1BF75", "url": "https://omabrowser.org/oma/group/E1BF75/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XRI7-1", "protein_name": "Establishment of sister chromatid cohesion N-acetyltransferase 1", "gene_name": "ESCO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAQKRKSALVEPSAKRPRLDKNSRPSSAKKEKEVSDAKHVSNKSNSNQCAVQEKSVLRTSVKSNSVNTNESELGTRMTTRSSGFNSGSKTVPDKKAQQQSKSTKSKEVCQKKPAQEIPKSKCVTAPSESGARRSQRLQQLTHVEEPARSLRSREVKEEKALDVKQSSQAKRPAQNVPAKALKPAGEKAEQKNTKTKSNNAKEDKETRVEVTSSPKEKKCKADKKNDNSKSLQHSVQDSSLCPDDGLEEVKKDQKDPVSPVLSSTKKVKADSPKPNSKTVTKEKQQVHQNIKGSIKPNKVSQPSVSETKVADQPESDVKSKRVSILELCEEIAGEIESDTVEVKKDSPNAECSKTEEEKHAEVQLQQSEMLTQKEPAQSAQCKRFFPSKKGMPVKCTLNGRSNSSNKNSKWTKIKLLKANNMKQTNLNSANAPKLSLLKNFPEVSEASQIATEAQHSKVEGQLPVTRLSENESATCVQDKSDPSSERAGSKEVALEMKQPTKRGVENGLLHNLTKHFSEPRPDENFKLRLESSPESSPVKHLTAPKPSKQLKREPGECDPQVVGLAPKQLTHTSSTNQTSEPENRVPSTNPALTSKCSNLLPSEEHIQKLKEAGKDGEKQLIIDAGQKRFGAISCNICGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPDDPKYALKKVEEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVIGCLIAEHIQWGYRVIEEKVPEISSENEMVIFERQKAWCCSTSPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFLNGQHQA", "length": 856 }, "evidence": [ { "id": "E1BF75", "url": "https://omabrowser.org/oma/group/E1BF75/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5FWF5-1", "protein_name": "N-acetyltransferase ESCO1", "gene_name": "ESCO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST", "length": 840 }, "evidence": [ { "id": "E1BF75", "url": "https://omabrowser.org/oma/group/E1BF75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-lysine-acetyltransferase activity", "id": "GO:0061733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061733", "evidence": [ { "database": "UniProtKB", "id": "E1BF75", "url": "https://www.uniprot.org/uniprotkb/E1BF75" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BF75", "url": "https://www.uniprot.org/uniprotkb/E1BF75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BF75", "url": "https://www.uniprot.org/uniprotkb/E1BF75" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BF75", "url": "https://www.uniprot.org/uniprotkb/E1BF75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "E1BF75", "url": "https://www.uniprot.org/uniprotkb/E1BF75" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "E1BF75", "url": "https://www.uniprot.org/uniprotkb/E1BF75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 839, "end_pos": 841, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "45948", "name": "", "equation": "L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1MAE0-1", "A0A3Q1MLT2-1", "F2Z4J6-1", "F1MP98-1", "E1BEB3-1", "Q17QK9-1", "Q2KIN8-1", "A0A3Q1LU60-1", "A7YY28-1", "A0A3S5ZPM2-1", "A0ABZ3NNH7-1", "Q2NKW0-1", "F1MVD0-1" ], "evidence": [ { "id": "45948", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45948" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LU60", "gene_name": "KAT6B", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A3Q1LU60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU60" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A3Q1LU60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU60" } ] } ] }, { "uniprot_ac": "A0A3Q1MAE0", "gene_name": "CLOCK", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A3Q1MAE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAE0" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A3Q1MAE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAE0" } ] } ] }, { "uniprot_ac": "A0A3Q1MLT2", "gene_name": "KAT2B", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A3Q1MLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLT2" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A3Q1MLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLT2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPM2", "gene_name": "HAT1", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A3S5ZPM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPM2" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A3S5ZPM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPM2" } ] } ] }, { "uniprot_ac": "A0ABZ3NNH7", "gene_name": "KAT7", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0ABZ3NNH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0ABZ3NNH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7" } ] } ] }, { "uniprot_ac": "A7YY28", "gene_name": "ABHD14B", "activity": [ { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "A7YY28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YY28" } ] } ] }, { "uniprot_ac": "E1BEB3", "gene_name": "KAT6A", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "E1BEB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEB3" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "E1BEB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEB3" } ] } ] }, { "uniprot_ac": "F1MP98", "gene_name": "KAT8", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "F1MP98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP98" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "F1MP98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP98" } ] } ] }, { "uniprot_ac": "F1MVD0", "gene_name": "NCOA3", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "F1MVD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVD0" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "F1MVD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVD0" } ] } ] }, { "uniprot_ac": "F2Z4J6", "gene_name": "GTF2B", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "F2Z4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F2Z4J6" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "F2Z4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F2Z4J6" } ] } ] }, { "uniprot_ac": "Q17QK9", "gene_name": "NAA60", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "Q17QK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QK9" } ] }, { "ec_number": "2.3.1.259", "activity": "N-terminal L-methionyl-[transmembrane protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-[transmembrane protein] + CoA + H(+).", "evidence": [ { "id": "Q17QK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QK9" } ] }, { "ec_number": "2.3.1.259", "activity": "", "evidence": [ { "id": "Q17QK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QK9" } ] } ] }, { "uniprot_ac": "Q2KIN8", "gene_name": "GTF2B", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "Q2KIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIN8" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "Q2KIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIN8" } ] } ] }, { "uniprot_ac": "Q2NKW0", 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"MADSGRTPQARALLQQCLHARLQVRPAEGDVEAEWVEVQRGLAIYVCFFKGADKELLPKMVNTLLNVKLSETENGKHVSILDLPGNILIIPQATLGGRVKGRSMQYHCNSGKEEGLELYSQFVNLCKKELAANSKCAEAGVVVKHGTYGNRQVLKLDTNGPYTHLIEF", "length": 168, "header": "tr|E1BF78-1|E1BF78_BOVIN Isoform 1 of D-aminoacyl-tRNA deacylase 2 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BF78-1" }, "isoforms": [ { "isoform_ac": "E1BF78-1", "url": "https://www.uniprot.org/uniprotkb/E1BF78/entry#E1BF78-1", "sequence": { "sequence": "MADSGRTPQARALLQQCLHARLQVRPAEGDVEAEWVEVQRGLAIYVCFFKGADKELLPKMVNTLLNVKLSETENGKHVSILDLPGNILIIPQATLGGRVKGRSMQYHCNSGKEEGLELYSQFVNLCKKELAANSKCAEAGVVVKHGTYGNRQVLKLDTNGPYTHLIEF", "length": 168, "header": "tr|E1BF78-1|E1BF78_BOVIN Isoform 1 of D-aminoacyl-tRNA deacylase 2 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BF78-1" }, "locus": { "chromosome": "11", "start_pos": 36215112, "end_pos": 36214609, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003831.5", "url": 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9913, "evidence": [ { "database": "UniProtKB", "id": "E1BF87", "url": "https://www.uniprot.org/uniprotkb/E1BF87" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRRX2", "url": "https://www.uniprot.org/uniprotkb/E1BF87", "locus": { "chromosome": "11", "start_pos": 100110981, "end_pos": 100059314, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002936", "url": "https://www.ensembl.org/id/ENSBTAG00000002936" } ] } } ], "crossref": [ { "id": "E1BF87", "url": "https://alphafold.ebi.ac.uk/entry/E1BF87", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002936", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002936", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534258", "url": 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{ "id": "KAREYSM", "url": "https://omabrowser.org/oma/group/KAREYSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BF87", "url": "https://www.orthodb.org/?gene=E1BF87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46385", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46385", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46385:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46385:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024855356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855356", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BF87", "url": "https://www.uniprot.org/uniprotkb/E1BF87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF87-1", "url": "https://www.uniprot.org/uniprotkb/E1BF87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSAAGPAFAPDKPALGPGPPPPPPGLGPGDCAQARKNFTVSHLLDLEEVAAAGRLAARPAPRAEAREGAAREPSGGSSGSEAAPQDGECPSPGRSSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLANRSASLLKSYSQEAAIEQPVAPRPTTLSPDYLSWTASSPYSTVPPYSPGGSGPATPGVSMANSIASLRLKAKEFSLHHSQVPTVN", "length": 254, "header": "tr|E1BF87-1|E1BF87_BOVIN Isoform 1 of Paired related homeobox 2 OS=Bos taurus OX=9913 GN=PRRX2 PE=3 SV=3 CANONICAL=E1BF87-1" }, "isoforms": [ { "isoform_ac": "E1BF87-1", "url": "https://www.uniprot.org/uniprotkb/E1BF87/entry#E1BF87-1", "sequence": { "sequence": "MDSAAGPAFAPDKPALGPGPPPPPPGLGPGDCAQARKNFTVSHLLDLEEVAAAGRLAARPAPRAEAREGAAREPSGGSSGSEAAPQDGECPSPGRSSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLANRSASLLKSYSQEAAIEQPVAPRPTTLSPDYLSWTASSPYSTVPPYSPGGSGPATPGVSMANSIASLRLKAKEFSLHHSQVPTVN", "length": 254, "header": "tr|E1BF87-1|E1BF87_BOVIN Isoform 1 of Paired related homeobox 2 OS=Bos taurus OX=9913 GN=PRRX2 PE=3 SV=3 CANONICAL=E1BF87-1" }, "locus": { "chromosome": "11", "start_pos": 100110425, "end_pos": 100059513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003817.8", "url": "https://www.ensembl.org/id/ENSBTAT00000003817.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003817.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003817.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 224, "start_aa": "Thr", "end_pos": 224, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr224", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:534258", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534258", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JXV9-1", "protein_name": "Paired related homeobox 2", "gene_name": "Prrx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSAAAAFALDPPAPGPGPPPAPGDCAQARKNFSVSHLLDLEEVAAAGRRAAGPVPGPEAREGAAREPSGGSSGSEAAPQDGDCPSPGHGSATKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLATRSASLLKSYGQEAAIEQPVAPRPTTLSPDYLSWPASSPYSSVPPYSPGGSSPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN", "length": 248 }, "evidence": [ { "id": "E1BF87", "url": "https://omabrowser.org/oma/group/E1BF87/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RQG1-1", "protein_name": "Paired related homeobox 2", "gene_name": "PRRX2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDSAAGAAFALDKPALGPGPPPPPSPALGPGDCAQARKNFTVSHLLDLEEVAAAGRLAARPAARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGGAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLANRSASLLKSYSQEAAIEQPVAPRPTTLSPDYLSWTASAPYSTVPPYSPGGSGPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN", "length": 255 }, "evidence": [ { "id": "E1BF87", "url": "https://omabrowser.org/oma/group/E1BF87/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q06348-1", "protein_name": "Paired mesoderm homeobox protein 2", "gene_name": "Prrx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSAAAAFALDPPAPGPGPPPAPGDCAQARKNFSVSHLLDLEEVAAAGRRAAGPVSGPAEARVGAAREPSGGSSGTEAAPQDGDCPSPGRGTKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLATRSASLLKSYGQEAAIEQPVAPRPTTMSPDYLSWPASSPYSSVPPYSPGGSSPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN", "length": 247 }, "evidence": [ { "id": "E1BF87", "url": "https://omabrowser.org/oma/group/E1BF87/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99811-1", "protein_name": "Paired mesoderm homeobox protein 2", "gene_name": "PRRX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSAAAAFALDKPALGPGPPPPPPALGPGDCAQARKNFSVSHLLDLEEVAAAGRLAARPGARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSPGSSGPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN", "length": 253 }, "evidence": [ { "id": "E1BF87", "url": "https://omabrowser.org/oma/group/E1BF87/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GIL1-1", "protein_name": "Paired related homeobox 2", "gene_name": "PRRX2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDSPPAFAMDKPFAPSTVRGPEPPENPQSRKNFSVSHLLDLEEVAAGMNGAPPAGPPPSAGGKAMPEPSGGSSGSEAAPQDGESLSPSRGVAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLANRSASLLKSYSQEAAIEQPMAPRPTALSPEYLSWSSSSPYSTVPSYSSSGTATPTQGVNMANSIASLRLKAKEFSLHQNQVPTVN", "length": 247 }, "evidence": [ { "id": "E1BF87", "url": "https://omabrowser.org/oma/group/E1BF87/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BF87", "url": "https://www.uniprot.org/uniprotkb/E1BF87" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BF87", "url": "https://www.uniprot.org/uniprotkb/E1BF87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BF87", "url": "https://www.uniprot.org/uniprotkb/E1BF87" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BF87", "url": "https://www.uniprot.org/uniprotkb/E1BF87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BF87-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 254, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BF87-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BF87" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BF87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF87" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 103, "end_pos": 163, "start_aa": "Lys", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BF87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF87" }, { "id": "PS50803", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50803" } ], "ann_type": 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}, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BF94-1", "uniprot_ac": "E1BF94", "uniprot_id": "E1BF94_BOVIN", "mass": { "chemical_mass": 76274.0, "monoisotopic_mass": 76274.0 }, "refseq": {}, "gene_names": [ { "name": "KBTBD6", "type": "recommended", "evidence": [ { "id": "E1BF94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF94" } ] } ], "protein_names": [ { "name": "Kelch repeat and BTB domain containing 6", "type": "synonym", "evidence": [ { "id": "E1BF94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF94/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BF94", "url": "https://www.uniprot.org/uniprotkb/E1BF94" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KBTBD6", "url": "https://www.uniprot.org/uniprotkb/E1BF94", "locus": { "chromosome": "12", "start_pos": 11333417, "end_pos": 11336403, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008656", "url": "https://www.ensembl.org/id/ENSBTAG00000008656" } ] } } ], "crossref": [ { "id": "E1BF94", "url": "https://alphafold.ebi.ac.uk/entry/E1BF94", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008656", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008656", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BF94", "url": "https://www.orthodb.org/?gene=E1BF94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF385", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF385", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": 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"MLHEAKDRQKFVSDVQYLRDMQHKVDSEYQACLRRQEYKRDPNEKKRDQFWGQETNFERSRFSSGSSSKQSSADEDAQAEPRLSATSSACKTDSRLPAIDQTSVKQKHKSTMTPKKLEKAGPSKPPPAAEAPQILSRKRRPNLGRLTVSPETQSPRLSGDRSRQKLQRPGKVPALRGIDPIVQQEHPAWASDTKLKRPTQERRNLVPSSQVIMVMENSRTERARKGDTGTHSQSTPHSALPQAFQGTHSPQELDESLGPPLVASTLGGPRRTTFRFRDKDFYSILSSNPGGEHDDTEEETHMEEELLMAGMHPPRSPSSHKRSRFLGTLATQAKNKNSEENPAHCRANSIRRSEASHGSLRISNAMEPVTEQSSVGQRMSQDPGLSDGGSIKGKDSSDCESEKKASHSWDTQSEPSLEDDINAENESRDGISMEERPGTHAYERDCQAYLSESSNPLDSFLAGRPMAPRSSVNLSHNMPGSVTHFTLRDDTLADLPPSSTLVPSSDSEGSSRFSGHQPLSPIRNRNLLAGAENCSYLPVDSAHDLDVRGAEDVTSTSPAQEAPLYTDGLLPNPQGNLSLMESSSSSPSGMNVQGHLHVARSLQENRPFTFFAGSEFPNQNENGSGMEFSGFTKAKGAPKMKTDPEKLKKIQESLLEEDSEEEGDLCRICQIAGGSPTNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQSLLVNLDDFNVTEFYQKHQQSRVQNELMNSGLYLVLLLHLYEQRFAELMRLNHDRATRERLSRNYPQPRLEENESSELGDGSGSSL", "length": 809, "header": "tr|E1BFD3-1|E1BFD3_BOVIN Isoform 1 of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=MARCHF10 PE=4 SV=3 CANONICAL=E1BFD3-1" }, "isoforms": [ { "isoform_ac": "E1BFD3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFD3/entry#E1BFD3-1", "sequence": { "sequence": "MLHEAKDRQKFVSDVQYLRDMQHKVDSEYQACLRRQEYKRDPNEKKRDQFWGQETNFERSRFSSGSSSKQSSADEDAQAEPRLSATSSACKTDSRLPAIDQTSVKQKHKSTMTPKKLEKAGPSKPPPAAEAPQILSRKRRPNLGRLTVSPETQSPRLSGDRSRQKLQRPGKVPALRGIDPIVQQEHPAWASDTKLKRPTQERRNLVPSSQVIMVMENSRTERARKGDTGTHSQSTPHSALPQAFQGTHSPQELDESLGPPLVASTLGGPRRTTFRFRDKDFYSILSSNPGGEHDDTEEETHMEEELLMAGMHPPRSPSSHKRSRFLGTLATQAKNKNSEENPAHCRANSIRRSEASHGSLRISNAMEPVTEQSSVGQRMSQDPGLSDGGSIKGKDSSDCESEKKASHSWDTQSEPSLEDDINAENESRDGISMEERPGTHAYERDCQAYLSESSNPLDSFLAGRPMAPRSSVNLSHNMPGSVTHFTLRDDTLADLPPSSTLVPSSDSEGSSRFSGHQPLSPIRNRNLLAGAENCSYLPVDSAHDLDVRGAEDVTSTSPAQEAPLYTDGLLPNPQGNLSLMESSSSSPSGMNVQGHLHVARSLQENRPFTFFAGSEFPNQNENGSGMEFSGFTKAKGAPKMKTDPEKLKKIQESLLEEDSEEEGDLCRICQIAGGSPTNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQSLLVNLDDFNVTEFYQKHQQSRVQNELMNSGLYLVLLLHLYEQRFAELMRLNHDRATRERLSRNYPQPRLEENESSELGDGSGSSL", "length": 809, "header": "tr|E1BFD3-1|E1BFD3_BOVIN Isoform 1 of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=MARCHF10 PE=4 SV=3 CANONICAL=E1BFD3-1" }, "locus": { "chromosome": "19", "start_pos": 47203436, "end_pos": 47110905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006082.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006082.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006082.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006082.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:540263", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540263", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9PX79-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Marchf10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLHETRDRQKFVSDVQYLRDMQHKVDSEYQACLKRQENKKEPNEKKQEQLWVRDTSDRSRFSSGSSCKQSSCEEDSRSEARLSTKTSSAKCEPRLPAIDQASVKQKHKGTMTLKKSEKVSPSKPSPVAPKILSRKRRPNLGRLTVSPEMHSPRASAERSRQKPQLSTKASGLLGADPVVQQESLLCANETKLKKPARERRKLAPSSQLMRTAGKPREKQKKGDLSAHPQNEPHTALSQTFQPMNGSQMLNESLGPSLLPATVVGPRRTPFRFHDEDFYSAISLNNEQESYDTEEETHMEEELLLSGMRSPPSYKRSRFLGTSTAQNRNVEENAENLRGNSLRWSEPSPGSPRKTSTTEPATKQPSPGQRMLQDTRLPSELAKENPSGDQDEKTPVLGDAKSDGVIQVSADDVSSGGTVEDRSAVQNHERDWQHYYSGSRTSFDCLLSGRPTAPRSSMNPPYSAHGSLLHSALIDDIPANLSMSSILVPSSDLEENLRFNVRRPLSPIRNRNPLAAAEGRSDEAQGTQEMASTSHIQEPPLLADLPNPQSSVALGDSPSSPTRRHLQGHFYMPGSLQENIPFTFFAVSDFANQNDNGTTVRVSGVMDEKATEIKADPEKLRKLQESLLEEDSEEEEGDLCRICQIAGGSPANPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGTVKTCEMCKQGLLVDLDDFNMTEFYHKHQQSRAQSELMNSGLYLVLLLHLYEQRFAELMALNYRRASRERLSRNYPQPRPEENESSESGDGNASNIYPGRVI", "length": 788 }, "evidence": [ { "id": "E1BFD3", "url": "https://omabrowser.org/oma/group/E1BFD3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5XIV2-1", "protein_name": "Probable E3 ubiquitin-protein ligase MARCHF10", "gene_name": "Marchf10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLHEARDRQKFVSDVQYLRDMQHKVDSEYQACLKRQEHKKEPNEKKQEQLWGKDTSDRSRFSSGSSCKQSSGEEDSLSEARLATKAPTAKCEPKLPAIDQTSVKQKHKGTMTLKKPEKVSPSKPSAVAQATKILSRKRRPNLGRLTVSPEMHSPRLSGERSRQKAQLSTKTSGLLGADPVVQQDSLLSANEMKLKRPAREKRNLAPSSQLVRVAGKAPLERQKKGDPSARPQNEPHTALSQTFQPMSGSQVLTESSVPPFLPATVVGPRRAPFRFHDEDFYSALSLNNEQENYDTEEETRTEEELLLAGMRSPPSYKRSRFLGTSAAQNRNVEENAENLRGNSLRRSEPNPGSPRKTSVTEPTTKQSSPGQRMLQDTRLPRELAKDNPSGDQDEKTPVPGDAKSDGVTQVSAEDVSNNCAVEDRSAVHNCERDWQRYLSGSRNSFDCLLSGRPTAPRASVNPSYNAHGSLFHSAVIDDIPASLSVSSILVPSAELEENLRFNVRRPLSPIRNRNPSAASESHSEDTQGEEERASTSQAQESPLLSDLPNPQSSMALGDSPSSPTRRHLQGHFYMPGSLQENIPFTFFAVSDFASQNDNGTSVRVSGVMDEKATEIKADPEKLRKLQESLLEEDSEEEGDLCRICQIAGGSPANPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLSTVKTCEMCKQGLLVDLDDFNMTEFYHKHQQSRAQSELMNSGLYLVLLLHLYEQRFAELMTLNYRRASRERMSRNYPQPRPEESESSESGDGNESNVYPGRVI", "length": 790 }, "evidence": [ { "id": "E1BFD3", "url": "https://omabrowser.org/oma/group/E1BFD3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NA82-1", "protein_name": "Probable E3 ubiquitin-protein ligase MARCHF10", "gene_name": "MARCHF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERSRFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQVVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENVWSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSALRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFAVREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTPFTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLVDLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRNYPQPRTEENENSELGDGNEGSISQSQVV", "length": 808 }, "evidence": [ { "id": "E1BFD3", "url": "https://omabrowser.org/oma/group/E1BFD3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BFD3", "url": "https://www.uniprot.org/uniprotkb/E1BFD3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BFD3", "url": "https://www.uniprot.org/uniprotkb/E1BFD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 733, "end_pos": 735, "annotation": "n_glycosylation_sequon" }, { "start_pos": 796, "end_pos": 798, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFD3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 809, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFD3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFD3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFD3" }, { "id": "PS51292", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51292" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-CH-type", "eco_id": "ECO_0000259", "start_pos": 658, "end_pos": 728, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 425, "end_pos": 427 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 622, "end_pos": 624 }, { "start_pos": 733, "end_pos": 735 }, { "start_pos": 796, "end_pos": 798 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFE3-1", "uniprot_ac": "E1BFE3", "uniprot_id": "E1BFE3_BOVIN", "mass": { "chemical_mass": 38612.0, "monoisotopic_mass": 38612.0 }, "refseq": { "ac": "XP_002696176", "name": "testis-expressed protein 19.2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696176" }, "gene_names": [ { "name": "LOC100299732", "type": "recommended", "evidence": [ { "id": "E1BFE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE3" } ] }, { "name": "LOC100299732", "type": "synonym", "evidence": [ { "id": "XP_002696176", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696176" } ] } ], "protein_names": [ { "name": "Testis expressed 19", "type": "recommended", "evidence": [ { "id": "E1BFE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE3/entry#names_and_taxonomy" } ] }, { "name": "testis-expressed protein 19.2", "type": "synonym", "evidence": [ { "id": "XP_002696176", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696176" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFE3", "url": "https://www.uniprot.org/uniprotkb/E1BFE3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC100299732", "url": "https://www.uniprot.org/uniprotkb/E1BFE3", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000050312", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000050312", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100299732", "url": "https://www.ncbi.nlm.nih.gov/gene/100299732", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100299732", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299732", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QQDLHRW", "url": "https://omabrowser.org/oma/group/QQDLHRW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFE3", "url": "https://www.orthodb.org/?gene=E1BFE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31387", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31387", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31387:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31387:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002696176", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696176", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BFE3", "url": "https://www.uniprot.org/uniprotkb/E1BFE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFE3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCPPVSKRYVAEGLSYLYVSWMYQLQHGSQLRLCFACFKVAFLDFKRMLESEDWEDEDWDSELMDDSEAWSEQGSSSGMGPSWGQGQGQPAQGGAVGWGSGTLASGPVESEDVGLHNHTVPTELQPQDAVPLGLGAEDADWTQGLPWRLEGLPTCSHWPSPLPPWRGFFKVDLPLGEPMVLELGTTQNMDPAETKAWLLDLQVLSLVGCCDVIYVQKMKPRRAWRTPGQCWKLLLEPDEWWVVRLQDAPQMQDLHHWKLSILESPSLEQNVDLVPADLVLLKRGLTILSFSPWAKREAAEGDSASRPQSSTQGGDAGTSGLREPGENLAAVGASALGELPHSQPLNPGSQN", "length": 351, "header": "tr|E1BFE3-1|E1BFE3_BOVIN Isoform 1 of Testis expressed 19 OS=Bos taurus OX=9913 GN=LOC100299732 PE=4 SV=3 CANONICAL=E1BFE3-1" }, "isoforms": [ { "isoform_ac": "E1BFE3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFE3/entry#E1BFE3-1", "sequence": { "sequence": "MCPPVSKRYVAEGLSYLYVSWMYQLQHGSQLRLCFACFKVAFLDFKRMLESEDWEDEDWDSELMDDSEAWSEQGSSSGMGPSWGQGQGQPAQGGAVGWGSGTLASGPVESEDVGLHNHTVPTELQPQDAVPLGLGAEDADWTQGLPWRLEGLPTCSHWPSPLPPWRGFFKVDLPLGEPMVLELGTTQNMDPAETKAWLLDLQVLSLVGCCDVIYVQKMKPRRAWRTPGQCWKLLLEPDEWWVVRLQDAPQMQDLHHWKLSILESPSLEQNVDLVPADLVLLKRGLTILSFSPWAKREAAEGDSASRPQSSTQGGDAGTSGLREPGENLAAVGASALGELPHSQPLNPGSQN", "length": 351, "header": "tr|E1BFE3-1|E1BFE3_BOVIN Isoform 1 of Testis expressed 19 OS=Bos taurus OX=9913 GN=LOC100299732 PE=4 SV=3 CANONICAL=E1BFE3-1" }, "locus": { "chromosome": "19", "start_pos": 50207829, "end_pos": 50206777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116015.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116015.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098460.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098460.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100299732", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299732", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZXL6-1", "protein_name": "Testis expressed gene 19.2", "gene_name": "Tex19.2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCPPVSVRHGAKGMSCLYGAWLYQLVHGEQMKICFACFKAAFLVVKNMLEMGDWEEEVWDAEPMELSEAGSEPEEWPGLSWGEGQGHTPHGISASTGSGAQAPGLVGTEGTGQGPQPVPTELGPQEAVPLDLGPEDAEWTQALPWRFDGLSPCSHWLIPPLSWWDIFNASPSPGQPVLLELSPTWPMDPLEAEAWLVDLKFVFLLGGFDAICYMLSMTPCWAVRTRVQRWQVLLDPGEVRVAQLQNAPEQQDLHRWKLSILESSELGVELVPADCSLRKGGFKVHSYLPWHNSTPEAWNREPGERLLVIEVVSLRELPCFRSPSPEPHN", "length": 329 }, "evidence": [ { "id": "E1BFE3", "url": "https://omabrowser.org/oma/group/E1BFE3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D5S1-1", "protein_name": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFF1-1", "uniprot_ac": "E1BFF1", "uniprot_id": "E1BFF1_BOVIN", "mass": { "chemical_mass": 52910.0, "monoisotopic_mass": 52910.0 }, "refseq": { "ac": "NP_001192608", "name": "bestrophin-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192608" }, "gene_names": [ { "name": "BEST4", "type": "recommended", "evidence": [ { "id": "E1BFF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF1" } ] }, { "name": "BEST4", "type": "synonym", "evidence": [ { "id": "NP_001192608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192608" } ] } ], "protein_names": [ { "name": "Bestrophin", "type": "recommended", "evidence": [ { "id": "E1BFF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF1/entry#names_and_taxonomy" } ] }, { "name": "bestrophin-4", "type": "synonym", "evidence": [ { "id": "NP_001192608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192608" } ] } ], "function": [ { "annotation": "Forms calcium-sensitive chloride channels. Permeable to bicarbonate.", "evidence": [ { "database": "UniProtKB", "id": "E1BFF1", "url": "https://www.uniprot.org/uniprotkb/E1BFF1#function" }, { "database": "UniProtKB", "id": "RU363126", "url": "https://www.uniprot.org/uniprotkb/RU363126#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFF1", "url": "https://www.uniprot.org/uniprotkb/E1BFF1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BEST4", "url": "https://www.uniprot.org/uniprotkb/E1BFF1", "locus": { "chromosome": "3", "start_pos": 101229638, "end_pos": 101225439, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015288", "url": "https://www.ensembl.org/id/ENSBTAG00000015288" } ] } } ], "crossref": [ { "id": "E1BFF1", "url": "https://alphafold.ebi.ac.uk/entry/E1BFF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015288", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015288", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510542", "url": "https://www.ncbi.nlm.nih.gov/gene/510542", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510542", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510542", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQLISWP", "url": "https://omabrowser.org/oma/group/CQLISWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFF1", "url": "https://www.orthodb.org/?gene=E1BFF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10736:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10736:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192608", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BFF1", "url": "https://www.uniprot.org/uniprotkb/E1BFF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFF1-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVSYTLKVAEARFGGFSGLLLRWRGSIYKLLYKEFLLFIALYALLSVTYRLLLTQEQKRVYAQVARYCNRSADLIPLSFVLGFYVTMVVNRWWAQYTSIPLPDQLMCVISATVHGVDQRGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNKYWIPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVVTIAVYSFFALSLVGRQFVEPVAGAATPREPLEPGQAAGDLDMYVPLTTLLQFFFYAGWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDDMYQNLPPAEKDAYWDEDSAQPPYTVATVAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGPARPVTAQTPLLGRFLGVGAPSPAISLRNFGRIRAPRTPHLVRFRAEEGGDIEAADRIEEEASGSGDETQEP", "length": 467, "header": "tr|E1BFF1-1|E1BFF1_BOVIN Isoform 1 of Bestrophin OS=Bos taurus OX=9913 GN=BEST4 PE=3 SV=3 CANONICAL=E1BFF1-1" }, "isoforms": [ { "isoform_ac": "E1BFF1-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF1/entry#E1BFF1-1", "sequence": { "sequence": "MTVSYTLKVAEARFGGFSGLLLRWRGSIYKLLYKEFLLFIALYALLSVTYRLLLTQEQKRVYAQVARYCNRSADLIPLSFVLGFYVTMVVNRWWAQYTSIPLPDQLMCVISATVHGVDQRGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNKYWIPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVVTIAVYSFFALSLVGRQFVEPVAGAATPREPLEPGQAAGDLDMYVPLTTLLQFFFYAGWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDDMYQNLPPAEKDAYWDEDSAQPPYTVATVAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGPARPVTAQTPLLGRFLGVGAPSPAISLRNFGRIRAPRTPHLVRFRAEEGGDIEAADRIEEEASGSGDETQEP", "length": 467, "header": "tr|E1BFF1-1|E1BFF1_BOVIN Isoform 1 of Bestrophin OS=Bos taurus OX=9913 GN=BEST4 PE=3 SV=3 CANONICAL=E1BFF1-1" }, "locus": { "chromosome": "3", "start_pos": 101229601, "end_pos": 101225985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020330.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020330.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020330.6", "url": "https://www.ensembl.org/id/ENSBTAP00000020330.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:510542", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510542", "resource": "KEGG Pathway" }, { "id": "R-BTA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZYU3-1", "protein_name": "Bestrophin homolog", "gene_name": "BEST4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"MTVSYTLKVAEARFGAFSGLLFRWRGSIYKLLYREFLLFCALYATLNITYRLLLTQEQKRIYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQSGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNKYWVPCVWFTNLAAQARRDGRIRDDIALCLILEELNKYRAKCGMLFHYDWISIPLVYTQVVTIAVYSFFTLSLIGRQFVESDKESSPAPWYLDMFVPLTTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNQLIDRNFQVSLLSVDDMYQNLPPTEQDLYWDEARPQPPYTVATAAESQRPSFMGSTFNLRMSDDPEQCLQVEASRRFDLPAPVTQTSQTPLLGRFLAARAPSPAVSLQNLRTSHLLHLRPGGEEAEGRIEEAVDEGSENEAMEP", "length": 454 }, "evidence": [ { "id": "E1BFF1", "url": "https://omabrowser.org/oma/group/E1BFF1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NFU0-1", "protein_name": "Bestrophin-4", "gene_name": "BEST4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVSYTLKVAEARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRYVYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQRGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNKYWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVVTIAVYSFFALSLVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYAGWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQPPYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLGVGAPSPAISLRNFGRVRGTPRPPHLLRFRAEEGGDPEAAARIEEESAESGDEALEP", "length": 473 }, "evidence": [ { "id": "E1BFF1", "url": "https://omabrowser.org/oma/group/E1BFF1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BFF1", "url": "https://www.uniprot.org/uniprotkb/E1BFF1" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "E1BFF1", "url": "https://www.uniprot.org/uniprotkb/E1BFF1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "intracellularly calcium-gated chloride channel activity", "id": "GO:0005229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005229", "evidence": [ { "database": "UniProtKB", "id": "E1BFF1", "url": "https://www.uniprot.org/uniprotkb/E1BFF1" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "E1BFF1", "url": "https://www.uniprot.org/uniprotkb/E1BFF1" } ], "pmid": "" }, { "name": "bicarbonate channel activity", "id": "GO:0160133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160133", "evidence": [ { "database": "UniProtKB", "id": "E1BFF1", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF3/entry#names_and_taxonomy" } ] }, { "name": "NADPH oxidase 3", "type": "synonym", "evidence": [ { "id": "NP_001178262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178262" } ] }, { "name": "Neutrophil cytochrome b 91 kDa polypeptide", "type": "synonym", "evidence": [ { "id": "E1BFF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF3/entry#names_and_taxonomy" } ] }, { "name": "gp91-1", "type": "synonym", "evidence": [ { "id": "E1BFF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF3/entry#names_and_taxonomy" } ] }, { "name": "gp91-phox", "type": "synonym", "evidence": [ { "id": "E1BFF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF3/entry#names_and_taxonomy" } ] }, { "name": "p22 phagocyte B-cytochrome", "type": "synonym", "evidence": [ { "id": "E1BFF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalytic subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). In the activated complex, electrons are first transferred from NADPH to flavin adenine dinucleotide (FAD) and subsequently transferred via two heme molecules to molecular oxygen, producing superoxide through an outer-sphere reaction. Activation of the NADPH oxidase complex is initiated by the assembly of cytosolic subunits of the NADPH oxidase complex with the core NADPH oxidase complex to form a complex at the plasma membrane or phagosomal membrane. This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox. NADPH oxidase complex assembly is impaired through interaction with NRROS.", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3#function" }, { "database": "UniProtKB", "id": "ARBA00049971", "url": "https://www.uniprot.org/uniprotkb/ARBA00049971#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NOX3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3", "locus": { "chromosome": "9", "start_pos": 91998779, "end_pos": 92064844, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013551", "url": "https://www.ensembl.org/id/ENSBTAG00000013551" } ] } } ], "crossref": [ { 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"id": "IPR017927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:526999", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526999", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DENQAIH", "url": "https://omabrowser.org/oma/group/DENQAIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFF3", "url": "https://www.orthodb.org/?gene=E1BFF3", "database": "OrthoDB", "categories": [ "Protein 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"R-BTA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178262", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178262", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "63180", "url": "https://www.rhea-db.org/rhea/63180", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFF3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMGCWILNESLSIILVLSWLGVNLYLFINTFYWYEEEESFLYTRVILGSTLAWARASAVCLNFNCMLILLPVSRNLISFMRGTSACFRGPWRRQLDKNLKFHKLVAYGIVINATIHVGAHLFNLEHYYWSQSPEAEGLVAALSKLGDTPNETYLNPIRTFHTNTITELLTTIAGITGLLISLALILIMTSSTEFIRQVSYELFWYTHHVFIIFFIGLAIHGAGRIVRGQTPESLLLHNITLCRDHPEEWQVRCPVPQFSGKEPSAWKWVLGPMVLYACERIIRFWRFQQEVIITKVVSHPSGVLELCMKKRDFKMAPGQYVLIQCPSISTLEWHPFTLTSAPQEDFFSVHIRAAGDWTEALCKAFGVEGQPLKEPWSLPRLAVDGPFGAALTDVFHYRVSMCIAAGIGVTPFAALLKSIWYQCCEAQTQCKLNKVYFYWICRDPGAFEWFADLLLALETKMSEQGKAHFLSYHIFLTGWDENQAFHIALHWDENADVITGLRQKTYYGRPNWNHEFQQVAFSHPSSNIGVFFCGPKALSKILQKMCRVYSSADPRGVHFYYNRESF", "length": 566, "header": "tr|E1BFF3-1|E1BFF3_BOVIN Isoform 1 of NADPH oxidase 2 OS=Bos taurus OX=9913 GN=NOX3 PE=4 SV=2 CANONICAL=E1BFF3-1" }, "isoforms": [ { "isoform_ac": "E1BFF3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF3/entry#E1BFF3-1", "sequence": { "sequence": "MMGCWILNESLSIILVLSWLGVNLYLFINTFYWYEEEESFLYTRVILGSTLAWARASAVCLNFNCMLILLPVSRNLISFMRGTSACFRGPWRRQLDKNLKFHKLVAYGIVINATIHVGAHLFNLEHYYWSQSPEAEGLVAALSKLGDTPNETYLNPIRTFHTNTITELLTTIAGITGLLISLALILIMTSSTEFIRQVSYELFWYTHHVFIIFFIGLAIHGAGRIVRGQTPESLLLHNITLCRDHPEEWQVRCPVPQFSGKEPSAWKWVLGPMVLYACERIIRFWRFQQEVIITKVVSHPSGVLELCMKKRDFKMAPGQYVLIQCPSISTLEWHPFTLTSAPQEDFFSVHIRAAGDWTEALCKAFGVEGQPLKEPWSLPRLAVDGPFGAALTDVFHYRVSMCIAAGIGVTPFAALLKSIWYQCCEAQTQCKLNKVYFYWICRDPGAFEWFADLLLALETKMSEQGKAHFLSYHIFLTGWDENQAFHIALHWDENADVITGLRQKTYYGRPNWNHEFQQVAFSHPSSNIGVFFCGPKALSKILQKMCRVYSSADPRGVHFYYNRESF", "length": 566, "header": "tr|E1BFF3-1|E1BFF3_BOVIN Isoform 1 of NADPH oxidase 2 OS=Bos taurus OX=9913 GN=NOX3 PE=4 SV=2 CANONICAL=E1BFF3-1" }, "locus": { "chromosome": "9", "start_pos": 92064844, "end_pos": 91998782, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018021.5", "url": "https://www.ensembl.org/id/ENSBTAT00000018021.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018021.4", "url": "https://www.ensembl.org/id/ENSBTAP00000018021.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:526999", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526999", "resource": "KEGG Pathway" }, { "id": "R-BTA-5668599", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5668599", "resource": "Reactome", "description": "RHO GTPases Activate NADPH Oxidases" }, { "id": "R-BTA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XN18-1", "protein_name": "NADPH oxidase 3", "gene_name": "NOX3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MACWILNEKLSVLLLLVWLGLNLYLFIDTFHWYEDEDAYVYTRIMLGSTLAWARASATCLNFNCMLILLPVSRNLISFLRGASACCGGAPRRQLDKNIAFHKVVAYGIAVNATIHIVAHLINIERYHNSQSKEAGGLQNKLSGLGKRPNESYLNPIRTYETNTTGEVLTTIAGVTGVMITVAFVLIVTSSTELIRRSCYEVFWYTHHLFVVFFIGLIIHGTGQLVRGQTPHSLLLHNITYCKEHYLEWEKATQCPLPQFSGNKPVAWKWVVSPVVLYICERIVRFWRFQQEVVITKVVTHSSGVLELHMKKHGFKMEAGQYIFLQCTSISPLEWHPFTLTSAPEEDFFSVHIRVAGDWTAALFKAFGAEEKTFKELWMLPRLVVDGPYGSATTDVFHYGVSVCIAAGIGVTPFASILKSIWYKSCNPNTVLVLQKVYFYWICRDPSTFEWFADLLFLLETKMVEKGKNDFLSYHIFLTGWDENQATHIALHYDEKMDVITGLRQKTFYGRPNWDSEFKQLAENHPSNSIGVFFCGPKNLSKILQKMCSSYSTVDPRGVQFHYNEESF", "length": 567 }, "evidence": [ { "id": "E1BFF3", "url": "https://omabrowser.org/oma/group/E1BFF3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SB25-1", "protein_name": "NADPH oxidase 2", "gene_name": "NOX3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IMGSWILNESLSIIFVLAWLGVNLYLFIDTFCWYEDEESFLYTRVILGSALAWARASAVCLNFNCMLILLPISRNFISFMRGTSTCFRGPWRRQLDKNLKFHKLVAYGIAINAAIHIGAHLCNLERYHGSQSREADGLVAALSKLGDTPNETYLNPIRTFHTNTVTELLMTISGATGLLISLVLILMMTSSTESIRQASYELFWYTHHVFIIFFIGLTIHGAGRIVRGQTPESLLLHNVTFCRDHFAEWQTAARCPVPQFSGKEPSAWKWVLGPVVLYACERIIRFWRFQQEVVITKVVSHPSRVLELQMKKRNFKMAPGQYILIQCPSVSWLEWHPFTLTSAPQEDFFSVHIRVAGDWTEALYKAFGAEGQALREPWSLPRLAVDGPFGAALTDVFHYPVTMCIAAGIGVTPFAALLKSVWYRCCESQTQLKLSKVYFYWICRDPGAFAWFADLLLSLETRMSEQGKTHFLSYHIFLTGWDENQAFHIALHWDENTDVITGLKQKTFYGRPNWNNEFRRVAYSHPSSNIGVFFCGPKALSKIIQRMCRLYSSADPRGVHFYYSKESF", "length": 568 }, "evidence": [ { "id": "E1BFF3", "url": "https://omabrowser.org/oma/group/E1BFF3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q672J9-1", "protein_name": "NADPH oxidase 3", "gene_name": "Nox3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"MPTCWILNESVSFVVALLWLAINIYLFIDTFCWYAEEESFFYTRVILGSALAWARASAVCLNFNCMLILLPVSRNFVSLVRGTSVCCRGPWRRQLDKNLKFHKLVAYGIAVNSVIHIVAHLFNLERYHLGQAKDAEGLLAALSKLGNAPNESYLNPVRTLYTGTTTQLLMTVSGITGLVISLALILIMTSSTEFIRQSSYELFWYTHHIFIFLFISLAIHGGGRIIRGQTPESLRLHNVTFCRDHFDEWQEAASCPVPQFSGKEPSAWKWTLGPVVLYACEIIIRFWRSHQEVVITKVVSHPSAVLELHMKKRDFKMAPGQYIFIQCPSISPLEWHPFTLTSAPQEDFFSVHIRASGDWTEALLKAFGAEGQAPSELCSMPRLAVDGPFGGSLADVFHYPVSVCIATGIGVTPFASLLKSVWYKCCESQSLPGLSKVYFYWICRDAAAFEWFADLLLSLETQMSEQGKAHLLSYHIYLTGWDEYQAIHIALHWDESLDVITGLKQKTFYGRPNWNEEFKQIAYNHPSSSIGVFFCGPKAMSKTLQKMCRLYSSSDPRGVHFYYNKENF", "length": 568 }, "evidence": [ { "id": "E1BFF3", "url": "https://omabrowser.org/oma/group/E1BFF3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86GL4-1", "protein_name": "Superoxide-generating NADPH oxidase heavy chain subunit B", "gene_name": "noxB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNEKKELQQELELQEFQTPKNQQLEKLQEPNGEISSTGNETSESGISSPPISQNDNSNNENESLNITPNKPFVSMQEELQNLDIENIPIPPTIQTPKIYKNTNNLIHSKNNLSLPISLSQENIVKLDKVDIESNDQVNSNTDNNNNTNNNNNTNNNKNEKIGLRSKIFKSKIFIKIRGWWWHRGISTYIMLFYIALNIGVGVHMFYNMYHSDIFKFLGLSFCFSRTAARLINLNSAVILLPVLRNFLSWLRGTIVNNYIPIDKHLNFHKLCAFMLFCCTIIHCVGHYISFKKINDDVLKIDDGKSVAGDYLNININNFPDEKYLFFKSVPGITGHIMLLILILIVSSSMWRIRRPMFEIFWYVHHLFIPFYILLCFHGYSKILKKDPQSWMWIIAPFILYSIERLIRIARSKKRVILEKAIMHPSKVLELRMKRDNDNFNFKPGQYLYLNCPSIAYHEWHPFTITSAPDDPFISVHINIVGNWTRKLFKLLNPDNKLGLIQEDLKSTQNRGKRRILKIDGPFGAPAENFFKYRNLVLIGAGIGVTPFSSILRHLKNQNDKQTNADENHLKINKIYFIWISRQKNSFQWFTDILAELENDERIDSILEIHIFLTGALELDDYAKIKNAQKCHITNLHSKTLFGRPNFRSIFNQLTQLHQREKIGVFYCGNKALGKNIIKNCNKFNGKNNCHLIFHKENF", "length": 698 }, "evidence": [ { "id": "E1BFF3", "url": "https://omabrowser.org/oma/group/E1BFF3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9HBY0-1", "protein_name": "NADPH oxidase 3", "gene_name": "NOX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMGCWILNEGLSTILVLSWLGINFYLFIDTFYWYEEEESFHYTRVILGSTLAWARASALCLNFNCMLILIPVSRNLISFIRGTSICCRGPWRRQLDKNLRFHKLVAYGIAVNATIHIVAHFFNLERYHWSQSEEAQGLLAALSKLGNTPNESYLNPVRTFPTNTTTELLRTIAGVTGLVISLALVLIMTSSTEFIRQASYELFWYTHHVFIVFFLSLAIHGTGRIVRGQTQDSLSLHNITFCRDRYAEWQTVAQCPVPQFSGKEPSAWKWILGPVVLYACERIIRFWRFQQEVVITKVVSHPSGVLELHMKKRGFKMAPGQYILVQCPAISSLEWHPFTLTSAPQEDFFSVHIRAAGDWTAALLEAFGAEGQALQEPWSLPRLAVDGPFGTALTDVFHYPVCVCVAAGIGVTPFAALLKSIWYKCSEAQTPLKLSKVYFYWICRDARAFEWFADLLLSLETRMSEQGKTHFLSYHIFLTGWDENQALHIALHWDENTDVITGLKQKTFYGRPNWNNEFKQIAYNHPSSSIGVFFCGPKALSRTLQKMCHLYSSADPRGVHFYYNKESF", "length": 568 }, "evidence": [ { "id": "E1BFF3", "url": "https://omabrowser.org/oma/group/E1BFF3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "NADPH oxidase complex", "id": "GO:0043020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043020", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "defense response", "id": "GO:0006952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006952", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "pmid": "" }, { "name": "superoxide anion generation", "id": "GO:0042554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042554", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "pmid": "" }, { "name": "NAD(P)H oxidase H2O2-forming activity", "id": "GO:0016174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016174", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "pmid": "" }, { "name": "superoxide-generating NAD(P)H oxidase activity", "id": "GO:0016175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016175", "evidence": [ { "database": "UniProtKB", "id": "E1BFF3", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "63180", "name": "", "equation": "NADPH + 2 O2 = 2 superoxide + NADP(+) + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O46522-1", "F1MQX5-1" ], "evidence": [ { "id": "63180", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63180" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1MQX5", "gene_name": "NOX4", "activity": [ { "ec_number": "1.6.3.1", "activity": "NADH + O2 + H(+) = H2O2 + NAD(+).", "evidence": [ { "id": "F1MQX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQX5" } ] }, { "ec_number": "1.6.3.1", "activity": "", "evidence": [ { "id": "F1MQX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQX5" } ] } ] }, { "uniprot_ac": "O46522", "gene_name": "CYBB", "activity": [ { "ec_number": "1.6.3.-", "activity": "", "evidence": [ { "id": "O46522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46522" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFF3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 566, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFF3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFF3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF3" }, { "id": "PS51384", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51384" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAD-binding FR-type", "eco_id": "ECO_0000259", "start_pos": 286, "end_pos": 393, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFF5-1", "uniprot_ac": "E1BFF5", "uniprot_id": "E1BFF5_BOVIN", "mass": { "chemical_mass": 34916.0, "monoisotopic_mass": 34916.0 }, "refseq": { "ac": "NP_001376877", "name": "olfactory receptor 10Z1", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376877" }, "gene_names": [ { "name": "OR10Z1", "type": "recommended", "evidence": [ { "id": "E1BFF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF5" } ] }, { "name": "OR10Z1", "type": "synonym", "evidence": [ { "id": "NP_001376877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376877" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BFF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 10Z1", "type": "synonym", "evidence": [ { "id": "NP_001376877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376877" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376877", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376877" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BFF5", "url": "https://www.uniprot.org/uniprotkb/E1BFF5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFF5", "url": "https://www.uniprot.org/uniprotkb/E1BFF5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR10Z1", "url": "https://www.uniprot.org/uniprotkb/E1BFF5", "locus": { "chromosome": "3", "start_pos": 11100989, "end_pos": 11101942, "strand": "+", "evidence": 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001421716", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BFH5", "url": "https://www.uniprot.org/uniprotkb/E1BFH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFH5-1", "url": "https://www.uniprot.org/uniprotkb/E1BFH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGKKKSSFQITSVTLDYEGPGSPGGSDAPALPAPPGPPAPTGPSAPAPTGPPPRLPNGEPNPEPGGKSTPRNGSPPPGAPASRFRVVKLPQGLGEPYRRGRWTCVDVYERDLEPPSFSRLLEGIRGASGGNGGRSLDSRLELASLGLGAPTPQPGLSQVPTSWLRPPPTSPGPQARSFTGGLGQLAVPGKAKVETPPLSASPPQQRPPEPGTADSAGPSRAATPLPTLRVEAEAGGSAAAAAAAAGTPPLSRVKDGALRLRMELVAPEEMGQVPPVDSRPSSPALYFFPDASLVHKSPDPLGTVAAQSLNFARSMLAISGHLDSDDDSGSGSLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRDLAERNAALEQENGLLRALASPEQLAQLPSSGVPRLGPPAPNGPSV", "length": 415, "header": "tr|E1BFH5-1|E1BFH5_BOVIN Isoform 1 of TSC22 domain family member 4 OS=Bos taurus OX=9913 GN=TSC22D4 PE=3 SV=3 CANONICAL=E1BFH5-1" }, "isoforms": [ { "isoform_ac": "E1BFH5-1", "url": "https://www.uniprot.org/uniprotkb/E1BFH5/entry#E1BFH5-1", "sequence": { "sequence": "MSGGKKKSSFQITSVTLDYEGPGSPGGSDAPALPAPPGPPAPTGPSAPAPTGPPPRLPNGEPNPEPGGKSTPRNGSPPPGAPASRFRVVKLPQGLGEPYRRGRWTCVDVYERDLEPPSFSRLLEGIRGASGGNGGRSLDSRLELASLGLGAPTPQPGLSQVPTSWLRPPPTSPGPQARSFTGGLGQLAVPGKAKVETPPLSASPPQQRPPEPGTADSAGPSRAATPLPTLRVEAEAGGSAAAAAAAAGTPPLSRVKDGALRLRMELVAPEEMGQVPPVDSRPSSPALYFFPDASLVHKSPDPLGTVAAQSLNFARSMLAISGHLDSDDDSGSGSLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRDLAERNAALEQENGLLRALASPEQLAQLPSSGVPRLGPPAPNGPSV", "length": 415, "header": "tr|E1BFH5-1|E1BFH5_BOVIN Isoform 1 of TSC22 domain family member 4 OS=Bos taurus OX=9913 GN=TSC22D4 PE=3 SV=3 CANONICAL=E1BFH5-1" }, "locus": { "chromosome": "25", "start_pos": 36086974, "end_pos": 36078001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020310.8", "url": "https://www.ensembl.org/id/ENSBTAT00000020310.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020310.6", "url": "https://www.ensembl.org/id/ENSBTAP00000020310.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 43, "start_aa": "Thr", "end_pos": 43, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr43", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 51, "start_aa": "Thr", "end_pos": 51, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr51", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FYE2-1", "protein_name": "TSC22 domain family protein 4 isoform X2", "gene_name": "Tsc22d4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGGKKKSSFQITSVTTDYEGPGSPGASDSPASPAPVGPPPRLPNGEPNPDSGGRGTPRNGSPPPGAPASRFRVVKLPQGLGEPYRRGRWTCVDVYERDLEPPNFGRLLEGIRGASGGTGGRSLDSRLELASLGISTSIPQPGLSQSPTSWLRPPPTSPGPQARSFTGGLGQLAGPGKAKVETPPLSASPPQQRPPGPGTGDSAQPLPSLRVDVESGSSAAGTPPLSRRRDGAVPLRMELVGPDESGKVASIDSRPSSPALYFDASLAHKSPDPFGAAAAQSLSLARSMLAISGHLDSDDDSGSGSLVGIDNKIEQAMVLFWKCKTKPSMSEQPKKHPLKGVEKTSMDFGTIKLAKPHKESKVSDLDACPGVLEPCVLATVKERPTMHHESRQSRSLVQLSQTVVHSVSTLMFSALQSGWRLCRWKSSMSSASVSSRMRTGSALETTEAEMLREVYLVLWVIRKQLRELARRQERRRRRRMRSHASHTSRHSDPVQGLKQDARSPL", "length": 506 }, "evidence": [ { "id": "E1BFH5", "url": "https://omabrowser.org/oma/group/E1BFH5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1RMY6-1", "protein_name": "TSC22 domain family member 4", "gene_name": "TSC22D4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGGRKKSSFQITSVTTDYEGPGSPGGSDPPALPAPTGPPPRLPNGEPNPEPGGRGTPRNGSPPPGAPASRFRVVKLPQGLGEPYRRGRWTCVDVYERDLEPPSFGRLLEGIRGASGGTGGRSLDSRLELASLGLSAPAPQPGLSQGPTSWLRPPPTSPGPQARSLTGGLGQLAVPSKAKVETPPLSVSPPQQRPPEPGTGDSTGTSRAATPLPSLRVEVEAGGSTAGTPPLPWTKDGALRLRMEETGQVPPLDSRPGSPALYFFPEASLVRKSPDPFGAAAAQSLSLARSMLAISGHLDSDDDSGSGSLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRDLAERNAALEQENGLLRALASPEQLAQLPSSGVPRLGPPAPNGPSV", "length": 390 }, "evidence": [ { "id": "E1BFH5", "url": "https://omabrowser.org/oma/group/E1BFH5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3B8N7-1", "protein_name": "TSC22 domain family protein 4", "gene_name": "Tsc22d4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGGKKKSSFQITSVTTDYEGPGSPGASDPPAPPAPAGPPPRLPNGEPNPDPGGRGTPRNGSPPPGAPASRFRVVKLPQGLGEPYRRGRWTCVDVYERDLEPPSFGRLLEGIRGASGGTGGRSLDSRLELASLGISTPIPQPGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLAGPGKAKVETPPLSASPPQQRPPGPGTGDSAQTLPSLRVEVESGGLAAGTPPLSRRRDGAVRLRMELVAPEETGKVPPIDSRPNSPALYFDASLVHKSPDPFGAAAAQSLSLARSMLAISGHLDSDDDSGSGSLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRDLAERNAALEQENGLLRALASPEQLAQLPSSGLPRLGPSAPNGPSI", "length": 387 }, "evidence": [ { "id": "E1BFH5", "url": "https://omabrowser.org/oma/group/E1BFH5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9EQN3-1", "protein_name": "TSC22 domain family protein 4", "gene_name": "Tsc22d4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGGKKKSSFQITSVTTDYEGPGSPGASDSPVPPALAGPPPRLPNGDPNPDPGGRGTPRNGSPPPGAPASRFRVVKLPQGLGEPYRRGRWTCVDVYERDLEPPSFGRLLEGIRGASGGTGGRSLDSRLELASLGISTPIPQPGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLAGPGKAKVETPPLSASPPQQRPPGPGTGDSAQTLPSLRVEVESGGSAAATPPLSRRRDGAVRLRMELVAPAETGKVPPTDSRPNSPALYFDASLVHKSPDPFGAAAAQSLSLARSMLAISGHLDSDDDSGSGSLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRDLAERNAALEQENGLLRALASPEQLAQLPSSGLPRLGPSAPNGPSI", "length": 387 }, "evidence": [ { "id": "E1BFH5", "url": "https://omabrowser.org/oma/group/E1BFH5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3Q8-1", "protein_name": "TSC22 domain family protein 4", "gene_name": "TSC22D4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377476" }, "gene_names": [ { "name": "OR2T4", "type": "recommended", "evidence": [ { "id": "E1BFI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFI7" } ] }, { "name": "OR2T4", "type": "synonym", "evidence": [ { "id": "NP_001377476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377476" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BFI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFI7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 2 subfamily T member 4", "type": "synonym", "evidence": [ { "id": "NP_001377476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377476" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377476", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377476" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BFI7", "url": "https://www.uniprot.org/uniprotkb/E1BFI7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFI7", "url": "https://www.uniprot.org/uniprotkb/E1BFI7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2T4", "url": "https://www.uniprot.org/uniprotkb/E1BFI7", "locus": { "chromosome": "7", "start_pos": 42006495, "end_pos": 42005533, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000058733", "url": "https://www.ensembl.org/id/ENSBTAG00000058733" } ] } } ], "crossref": [ { "id": "E1BFI7", "url": "https://alphafold.ebi.ac.uk/entry/E1BFI7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "788190", "url": "https://www.ncbi.nlm.nih.gov/gene/788190", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:788190", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788190", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ITIHRMN", "url": "https://omabrowser.org/oma/group/ITIHRMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFI7", "url": "https://www.orthodb.org/?gene=E1BFI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-381753", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381753", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001377476", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377476", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BFI7", "url": "https://www.uniprot.org/uniprotkb/E1BFI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFI7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNNTWMTSYTERLDFTLVGIFSQSQHPALLCLVISVIFLMALSGNIILMFLIYSDAHLHTPMYFFISQLSFMDMMYISVTVPKMLTDQITGVNKISVPECGIQMFLYVTLAGSEFFLLASMAYDRYMAICHPLHYPVLMNHRVCLFLASGCWFLGSVDGFLFTPITMTFPFCRSQEIHHFFCEVPAVLKLSCSDTSLYEIFMYLCCVLMLLIPVTIISGSYYFILLTIHRMNSAEGRKKAFATCSSHMTVVILFYGAAIYTYMLPNSYHTPEKDMMVSVFYTILTPVLNPLIYSLRNKDVTGALKKMLNMGIVFQETIK", "length": 320, "header": "tr|E1BFI7-1|E1BFI7_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2T4 PE=3 SV=2 CANONICAL=E1BFI7-1" }, "isoforms": [ { "isoform_ac": "E1BFI7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFI7/entry#E1BFI7-1", "sequence": { "sequence": "MDNNTWMTSYTERLDFTLVGIFSQSQHPALLCLVISVIFLMALSGNIILMFLIYSDAHLHTPMYFFISQLSFMDMMYISVTVPKMLTDQITGVNKISVPECGIQMFLYVTLAGSEFFLLASMAYDRYMAICHPLHYPVLMNHRVCLFLASGCWFLGSVDGFLFTPITMTFPFCRSQEIHHFFCEVPAVLKLSCSDTSLYEIFMYLCCVLMLLIPVTIISGSYYFILLTIHRMNSAEGRKKAFATCSSHMTVVILFYGAAIYTYMLPNSYHTPEKDMMVSVFYTILTPVLNPLIYSLRNKDVTGALKKMLNMGIVFQETIK", "length": 320, "header": "tr|E1BFI7-1|E1BFI7_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2T4 PE=3 SV=2 CANONICAL=E1BFI7-1" }, "locus": { "chromosome": "7", "start_pos": 42006492, "end_pos": 42005533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053218.3", "url": "https://www.ensembl.org/id/ENSBTAT00000053218.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047851.2", "url": "https://www.ensembl.org/id/ENSBTAP00000047851.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:788190", "name": "", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "E1BFI7", "url": "https://www.uniprot.org/uniprotkb/E1BFI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFI7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFI7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFI7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFI7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 294, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698920" } ] }, { "name": "sPLA2-GXIIB", "type": "synonym", "evidence": [ { "id": "E1BFK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFK0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Not known; does not seem to have catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "E1BFK0", "url": "https://www.uniprot.org/uniprotkb/E1BFK0#function" }, { "database": "UniProtKB", "id": "ARBA00055969", "url": "https://www.uniprot.org/uniprotkb/ARBA00055969#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFK0", "url": "https://www.uniprot.org/uniprotkb/E1BFK0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PLA2G12B", "url": "https://www.uniprot.org/uniprotkb/E1BFK0", "locus": { "chromosome": "28", "start_pos": 28943314, "end_pos": 28963112, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009350", "url": "https://www.ensembl.org/id/ENSBTAG00000009350" } ] } } ], "crossref": [ { "id": "E1BFK0", "url": "https://alphafold.ebi.ac.uk/entry/E1BFK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009350", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009350", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100337447", "url": "https://www.ncbi.nlm.nih.gov/gene/100337447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100337447", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337447", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICQYRCR", "url": "https://omabrowser.org/oma/group/ICQYRCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFK0", "url": "https://www.orthodb.org/?gene=E1BFK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12824:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12824:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06951", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06951", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002698920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698920", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BFK0", "url": "https://www.uniprot.org/uniprotkb/E1BFK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFK0-1", "url": "https://www.uniprot.org/uniprotkb/E1BFK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTWAISFLILWLSLAGGLAQSDTSPDEEESYSDWGLRHIRGSFESVNSYFDSFMELLGGKNGVCQYRCRYGKAPMPRPGYKPQEPNGCSSYFLGLKVPERMDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKRSLGFVSNVEVACDSLADTVFNTVWTLGCRPFMNSQRAACICAEEEKDEL", "length": 195, "header": "tr|E1BFK0-1|E1BFK0_BOVIN Isoform 1 of Group XIIB secretory phospholipase A2-like protein OS=Bos taurus OX=9913 GN=PLA2G12B PE=3 SV=1 CANONICAL=E1BFK0-1" }, "isoforms": [ { "isoform_ac": "E1BFK0-1", "url": "https://www.uniprot.org/uniprotkb/E1BFK0/entry#E1BFK0-1", "sequence": { "sequence": "MTWAISFLILWLSLAGGLAQSDTSPDEEESYSDWGLRHIRGSFESVNSYFDSFMELLGGKNGVCQYRCRYGKAPMPRPGYKPQEPNGCSSYFLGLKVPERMDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKRSLGFVSNVEVACDSLADTVFNTVWTLGCRPFMNSQRAACICAEEEKDEL", "length": 195, "header": "tr|E1BFK0-1|E1BFK0_BOVIN Isoform 1 of Group XIIB secretory phospholipase A2-like protein OS=Bos taurus OX=9913 GN=PLA2G12B PE=3 SV=1 CANONICAL=E1BFK0-1" }, "locus": { "chromosome": "28", "start_pos": 28962913, "end_pos": 28944318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012306.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012306.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012306.4", "url": "https://www.ensembl.org/id/ENSBTAP00000012306.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100337447", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337447", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SU77-1", "protein_name": "Group XIIB secretory phospholipase A2-like protein", "gene_name": "PLA2G12B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLPTSFLILWLSLEGVLVQSGSSPDAEESYSDWGLRHIRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQEPNGCSSYFLGLKVPQSMDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKKSLGFVSNVEACDSLADTVFNTVWTLGCRPFMNSQRAACICAEEEKEEL", "length": 194 }, "evidence": [ { "id": "E1BFK0", "url": "https://omabrowser.org/oma/group/E1BFK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HJ25-1", "protein_name": "Group XIIB secretory phospholipase A2-like protein", "gene_name": "Pla2g12b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKLLCCFFLLWLGLAGSLAQSDPSLKGEESYSDWGLRHLRGSFESVNSYVDSFMELLGGKNGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGIKVPGSMDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKRSLGFVSNVEAACDSLADTVFNTVWTLGCRPFMNSQRAACICAEEEKEEL", "length": 195 }, "evidence": [ { "id": "E1BFK0", "url": "https://omabrowser.org/oma/group/E1BFK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0RCI5-1", "protein_name": "Group XIIB secretory phospholipase A2-like protein", "gene_name": "Pla2g12b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLLCAFFLLWLGLVGSLAQSDPSPKGEESYSDWGLRQLRGSFESVNSYVDSFMELLGGKNGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGIKVPGSMDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKRSLGFVSNVEACDSLADTVFNTVWTLGCRPFMNSQRAACICAEEEKEEL", "length": 194 }, "evidence": [ { "id": "E1BFK0", "url": "https://omabrowser.org/oma/group/E1BFK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BX93-1", "protein_name": "Group XIIB secretory phospholipase A2-like protein", "gene_name": "PLA2G12B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLASGFLVLWLSLGGGLAQSDTSPDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKRSLGFVSKVEAACDSLVDTVFNTVWTLGCRPFMNSQRAACICAEEEKEEL", "length": 195 }, "evidence": [ { "id": "E1BFK0", "url": "https://omabrowser.org/oma/group/E1BFK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VUV6-1", "protein_name": "GXIVsPLA2, isoform A", "gene_name": "GXIVsPLA2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQFSWMKVAIYLLTFLTYAYSGYGSSTIVHLRDAIIAAEAIFGDVFKNLIVLVRKFRTVHEVFDAAVDENCIYQCPAPDIGGPAPRAVQNKFYTPTADGCGSLGLRISTDYLPAKEMETCCNDHDICYDTCNSDKELCDLDFKRCLYKYCDSYEKSIASDLMMKGCKAAAKMLFTGTLTLGCRSYLDSQQRSCYCAPPKSSSYNGNRQGNSNSREKQQRQKYGWKDRNEI", "length": 230 }, "evidence": [ { "id": "E1BFK0", "url": "https://omabrowser.org/oma/group/E1BFK0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BFK0", "url": "https://www.uniprot.org/uniprotkb/E1BFK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "E1BFK0", "url": "https://www.uniprot.org/uniprotkb/E1BFK0" } ], "pmid": "" }, { "name": "arachidonate secretion", "id": "GO:0050482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050482", "evidence": [ { "database": "UniProtKB", "id": "E1BFK0", "url": "https://www.uniprot.org/uniprotkb/E1BFK0" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "E1BFK0", "url": "https://www.uniprot.org/uniprotkb/E1BFK0" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "E1BFK0", "url": "https://www.uniprot.org/uniprotkb/E1BFK0" } ], "pmid": "" }, { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "E1BFK0", "url": "https://www.uniprot.org/uniprotkb/E1BFK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BFK0", "url": "https://www.uniprot.org/uniprotkb/E1BFK0" } ], "pmid": "" }, { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "E1BFK0", "url": "https://www.uniprot.org/uniprotkb/E1BFK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFK0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 195, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFK0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFK0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFM2-1", "uniprot_ac": "E1BFM2", "uniprot_id": "E1BFM2_BOVIN", "mass": { "chemical_mass": 54750.0, "monoisotopic_mass": 54750.0 }, "refseq": { "ac": "XP_024839057", "name": "probable threonine protease PRSS50", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839057" }, "gene_names": [ { "name": "PRSS50", "type": "recommended", "evidence": [ { "id": "E1BFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFM2" } ] }, { "name": "PRSS50", "type": "synonym", "evidence": [ { "id": "XP_024839057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839057" } ] } ], "protein_names": [ { "name": "Probable threonine protease PRSS50", "type": "recommended", "evidence": [ { "id": "E1BFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFM2/entry#names_and_taxonomy" } ] }, { "name": "Serine protease 50", "type": "synonym", "evidence": [ { "id": "E1BFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFM2/entry#names_and_taxonomy" } ] }, { "name": "Testis-specific protease-like protein 50", "type": "synonym", "evidence": [ { "id": "E1BFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFM2/entry#names_and_taxonomy" } ] }, { "name": "probable threonine protease PRSS50", "type": "synonym", "evidence": [ { "id": "XP_024839057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839057" } ] } ], "function": [ { "annotation": "May be involved in proteolysis through its threonine endopeptidase activity.", "evidence": [ { "database": "UniProtKB", "id": "E1BFM2", "url": "https://www.uniprot.org/uniprotkb/E1BFM2#function" }, { "database": "UniProtKB", "id": "ARBA00056912", "url": "https://www.uniprot.org/uniprotkb/ARBA00056912#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFM2", "url": "https://www.uniprot.org/uniprotkb/E1BFM2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRSS50", "url": "https://www.uniprot.org/uniprotkb/E1BFM2", "locus": {} } ], "crossref": [ { "id": "E1BFM2", "url": "https://alphafold.ebi.ac.uk/entry/E1BFM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005019", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005019", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "518845", "url": "https://www.ncbi.nlm.nih.gov/gene/518845", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:518845", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518845", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BFM2", "url": "https://www.orthodb.org/?gene=E1BFM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24253", "url": 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"MPEEVQKLDEVRLRDSRKLLGQTAWESDVLPGGQRRGQKPGSPEPPASQRVTGTSEAPWQEATGGRPRGRGCPRPPHHREPSPAANGGRLRGAGPGSAVARRAPRRSRCFPQMEFWCELPAGRRGPPRPGTSTLALALASAGLLLLLLRPLGCLGAGDTLGALSTDVPADLDAPCAPSATCPSGRRRFPRQVTGGSPPPSISQYATSKASHNEFLPPCGFSYERDPTLRDPESMARRWPWMVSVRANGTHICAGTLIASEWVLTAAHCTTESDVTYSVRAGSPWIDRITKTSIDILAKEVIVHSRYRASRYWSWVGRANDIALLNLDRPLQYSKYVWPICLPGLDYSVKDYSLCTVTGWGLPRVDGQWPQFRTIQEKEVTILNSTECDSLYRRFSKIPSLIQIINSQMICAKDVDREKFCYEISGEPLACPVQNIWHLVGVVSWGPGCKKSEAPPIYIHISSYQQWIWDRISGQTLPAPSRALLLALLMLLSFLAAL", "length": 497, "header": "tr|E1BFM2-1|E1BFM2_BOVIN Isoform 1 of Probable threonine protease PRSS50 OS=Bos taurus OX=9913 GN=PRSS50 PE=4 SV=4 CANONICAL=E1BFM2-1" }, "isoforms": [ { "isoform_ac": "E1BFM2-1", "url": "https://www.uniprot.org/uniprotkb/E1BFM2/entry#E1BFM2-1", "sequence": { "sequence": "MPEEVQKLDEVRLRDSRKLLGQTAWESDVLPGGQRRGQKPGSPEPPASQRVTGTSEAPWQEATGGRPRGRGCPRPPHHREPSPAANGGRLRGAGPGSAVARRAPRRSRCFPQMEFWCELPAGRRGPPRPGTSTLALALASAGLLLLLLRPLGCLGAGDTLGALSTDVPADLDAPCAPSATCPSGRRRFPRQVTGGSPPPSISQYATSKASHNEFLPPCGFSYERDPTLRDPESMARRWPWMVSVRANGTHICAGTLIASEWVLTAAHCTTESDVTYSVRAGSPWIDRITKTSIDILAKEVIVHSRYRASRYWSWVGRANDIALLNLDRPLQYSKYVWPICLPGLDYSVKDYSLCTVTGWGLPRVDGQWPQFRTIQEKEVTILNSTECDSLYRRFSKIPSLIQIINSQMICAKDVDREKFCYEISGEPLACPVQNIWHLVGVVSWGPGCKKSEAPPIYIHISSYQQWIWDRISGQTLPAPSRALLLALLMLLSFLAAL", "length": 497, "header": "tr|E1BFM2-1|E1BFM2_BOVIN Isoform 1 of Probable threonine protease PRSS50 OS=Bos taurus OX=9913 GN=PRSS50 PE=4 SV=4 CANONICAL=E1BFM2-1" }, "locus": { "chromosome": "22", "start_pos": 52778841, "end_pos": 52773343, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055134.5", "url": "https://www.ensembl.org/id/ENSBTAT00000055134.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047813.4", "url": "https://www.ensembl.org/id/ENSBTAP00000047813.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:518845", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518845", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "E1BFM2", "url": "https://www.uniprot.org/uniprotkb/E1BFM2" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "E1BFM2", "url": "https://www.uniprot.org/uniprotkb/E1BFM2" } ], "pmid": "" }, { "name": "threonine-type endopeptidase activity", "id": "GO:0004298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004298", "evidence": [ { "database": "UniProtKB", "id": "E1BFM2", "url": "https://www.uniprot.org/uniprotkb/E1BFM2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BFM2", "url": "https://www.uniprot.org/uniprotkb/E1BFM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "E1BFM2", "url": "https://www.uniprot.org/uniprotkb/E1BFM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFM2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 497, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFM2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFM2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFM2" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 192, "end_pos": 472, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFM3-1", "uniprot_ac": "E1BFM3", "uniprot_id": "E1BFM3_BOVIN", "mass": { "chemical_mass": 14554.0, "monoisotopic_mass": 14554.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Large ribosomal subunit protein uL29", "type": "recommended", "evidence": [ { "id": "E1BFM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFM3/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L35", "type": "synonym", "evidence": [ { "id": "E1BFM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFM3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFM3", "url": "https://www.uniprot.org/uniprotkb/E1BFM3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BFM3", "locus": {} } ], "crossref": [ { "id": "E1BFM3", "url": "https://alphafold.ebi.ac.uk/entry/E1BFM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000027075", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000027075", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00427", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00427", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NMANECI", "url": "https://omabrowser.org/oma/group/NMANECI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45722", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45722", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45722:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45722:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BFM3", "url": "https://www.uniprot.org/uniprotkb/E1BFM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFM3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLEDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVTNQTQKENLRKFYKGKKYEPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLRKYAVKA", "length": 123, "header": "tr|E1BFM3-1|E1BFM3_BOVIN Isoform 1 of Large ribosomal subunit protein uL29 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=E1BFM3-1" }, "isoforms": [ { "isoform_ac": "E1BFM3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFM3/entry#E1BFM3-1", "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLEDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVTNQTQKENLRKFYKGKKYEPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLRKYAVKA", "length": 123, "header": "tr|E1BFM3-1|E1BFM3_BOVIN Isoform 1 of Large ribosomal subunit protein uL29 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=E1BFM3-1" }, "locus": { "chromosome": "21", "start_pos": 13957791, "end_pos": 13957423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013301.6", "url": "https://www.ensembl.org/id/ENSBTAT00000013301.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051069.2", "url": "https://www.ensembl.org/id/ENSBTAP00000051069.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "O80626-1", "protein_name": "Large ribosomal subunit protein uL29y", "gene_name": "RPL35B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARIKVHELREKSKADLSGQLKEFKAELALLRVAKVTGGAPNKLSKIKVVRKSIAQVLTVISQKQKSALREAYKNKKLLPLDLRPKKTRAIRRRLTKHQASLKTEREKKKEMYFPIRKYAIKV", "length": 123 }, "evidence": [ { "id": "E1BFM3", "url": "https://omabrowser.org/oma/group/E1BFM3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0CX84-1", "protein_name": "Large ribosomal subunit protein uL29A", "gene_name": "RPL35A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA", "length": 120 }, "evidence": [ { "id": "E1BFM3", "url": "https://omabrowser.org/oma/group/E1BFM3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P0CX85-1", "protein_name": "Large ribosomal subunit protein uL29B", "gene_name": "RPL35B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA", "length": 120 }, "evidence": [ { "id": "E1BFM3", "url": "https://omabrowser.org/oma/group/E1BFM3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6ZWV7-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "Rpl35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLTKHEEKLKTKKQQRKERLYPLRKYAVKA", "length": 123 }, "evidence": [ { "id": "E1BFM3", "url": "https://omabrowser.org/oma/group/E1BFM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1BFM3", "url": "https://www.uniprot.org/uniprotkb/E1BFM3" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "E1BFM3", "url": "https://www.uniprot.org/uniprotkb/E1BFM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "E1BFM3", "url": "https://www.uniprot.org/uniprotkb/E1BFM3" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "E1BFM3", "url": "https://www.uniprot.org/uniprotkb/E1BFM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "E1BFM3", "url": "https://www.uniprot.org/uniprotkb/E1BFM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFM3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 123, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFM3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFM3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFR3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFR3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFR3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFT5-1", "uniprot_ac": "E1BFT5", "uniprot_id": "E1BFT5_BOVIN", "mass": { "chemical_mass": 38305.0, "monoisotopic_mass": 38305.0 }, "refseq": { "ac": "NP_001192771", "name": "inhibin beta E chain precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192771" }, "gene_names": [ { "name": "INHBE", "type": "recommended", "evidence": [ { "id": "E1BFT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFT5" } ] }, { "name": "INHBE", "type": "synonym", "evidence": [ { "id": "NP_001192771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192771" } ] } ], "protein_names": [ { "name": "Inhibin subunit beta E", "type": "synonym", "evidence": [ { "id": "E1BFT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFT5/entry#names_and_taxonomy" } ] }, { "name": "inhibin beta E chain precursor", "type": "synonym", "evidence": [ { "id": "NP_001192771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192771" } ] }, { "name": "inhibin beta E subunit", "type": "synonym", "evidence": [ { "id": "NP_001192771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192771" } ] }, { "name": "inhibin, beta E", "type": "synonym", "evidence": [ { "id": "NP_001192771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192771" } ] } ], "function": [ { "annotation": "Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.", "evidence": [ { "database": "UniProtKB", "id": "E1BFT5", "url": "https://www.uniprot.org/uniprotkb/E1BFT5#function" }, { "database": "UniProtKB", "id": "ARBA00002588", "url": "https://www.uniprot.org/uniprotkb/ARBA00002588#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFT5", "url": "https://www.uniprot.org/uniprotkb/E1BFT5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "INHBE", "url": "https://www.uniprot.org/uniprotkb/E1BFT5", "locus": { "chromosome": "5", "start_pos": 56004634, "end_pos": 56007200, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006599", "url": "https://www.ensembl.org/id/ENSBTAG00000006599" } ] } } ], "crossref": [ { "id": "E1BFT5", "url": "https://alphafold.ebi.ac.uk/entry/E1BFT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006599", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006599", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19406", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19406", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "517587", "url": "https://www.ncbi.nlm.nih.gov/gene/517587", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001318", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001318", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:517587", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517587", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETPLCCR", "url": "https://omabrowser.org/oma/group/ETPLCCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFT5", "url": "https://www.orthodb.org/?gene=E1BFT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11848", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11848", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11848:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11848:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00019", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00019", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-209822", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-209822", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192771", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192771", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BFT5", "url": "https://www.uniprot.org/uniprotkb/E1BFT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFT5-1", "url": "https://www.uniprot.org/uniprotkb/E1BFT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLLKVQLQLVLLWALVWAQVAGSACPSCGGPTLAPQAERALVLKLAKQQILEGLQLTSRPRLTHPPPKAVLTRALRRLQRGRVVPANGEQVISFAVLTDSSTATCSSTLTFHLSTPRSHHLYHARLWLQVLPTLPGPLSLRIFRWGGRRRGRGSRVFLAEHQLTTPGWHALTLPSSGLKREESGVLKLRLDCSPLEGNRTVTPQLLDTAGEQRPFLELKTRPKLPGAGRARRRTPSCEPATPLCCRRDHYVDFQELGWRDWILQPEGYRLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPLGTSCCVPTARRPLSLLYLDRDGNVVKTDVPDMVVEACGCS", "length": 348, "header": "tr|E1BFT5-1|E1BFT5_BOVIN Isoform 1 of Inhibin subunit beta E OS=Bos taurus OX=9913 GN=INHBE PE=3 SV=1 CANONICAL=E1BFT5-1" }, "isoforms": [ { "isoform_ac": "E1BFT5-1", "url": "https://www.uniprot.org/uniprotkb/E1BFT5/entry#E1BFT5-1", "sequence": { "sequence": "MGLLKVQLQLVLLWALVWAQVAGSACPSCGGPTLAPQAERALVLKLAKQQILEGLQLTSRPRLTHPPPKAVLTRALRRLQRGRVVPANGEQVISFAVLTDSSTATCSSTLTFHLSTPRSHHLYHARLWLQVLPTLPGPLSLRIFRWGGRRRGRGSRVFLAEHQLTTPGWHALTLPSSGLKREESGVLKLRLDCSPLEGNRTVTPQLLDTAGEQRPFLELKTRPKLPGAGRARRRTPSCEPATPLCCRRDHYVDFQELGWRDWILQPEGYRLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPLGTSCCVPTARRPLSLLYLDRDGNVVKTDVPDMVVEACGCS", "length": 348, "header": "tr|E1BFT5-1|E1BFT5_BOVIN Isoform 1 of Inhibin subunit beta E OS=Bos taurus OX=9913 GN=INHBE PE=3 SV=1 CANONICAL=E1BFT5-1" }, "locus": { "chromosome": "5", "start_pos": 56006928, "end_pos": 56005638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008663.5", "url": "https://www.ensembl.org/id/ENSBTAT00000008663.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008663.3", "url": "https://www.ensembl.org/id/ENSBTAP00000008663.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:517587", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517587", "resource": "KEGG Pathway" }, { "id": "R-BTA-209822", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-209822", "resource": "Reactome", "description": "Glycoprotein hormones" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HW41-1", "protein_name": "Inhibin beta E chain", "gene_name": "Inhbe", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLSDVQLWPVLLWALAWLQSTRSACPSCGGPTLAPQGERALVLELAKKQILEGLHLTSRPRITRPLPQAALTRALRRLQPRNLAPGNREEVISFATTVDKSTSTYRCMLTFQLSPLRSHHLYHARLWLHVPPSFPGTLYLRIFRCGTKSCRGYRTFLAEHRTTSSGWHALTLPSSGLRSDDSGVVKLQLDYRPLDPNSTVIPLPRRLLDTEGQQHPFLELKIRANEPGAGRARRRTPTCAPETPLCCRRDHYVDFQELGWRDWILQPEGYHLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPVGSSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS", "length": 350 }, "evidence": [ { "id": "E1BFT5", "url": "https://omabrowser.org/oma/group/E1BFT5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08717-1", "protein_name": "Inhibin beta E chain", "gene_name": "Inhbe", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLPKAQLWLILLWALVWVQSTRSACPSCGGPTLAPQGERALVLELAKQQILEGLHLTSRPRITRPLPQAALTRALRRLQPKSMVPGNREKVISFATIIDKSTSTYRSMLTFQLSPLWSHHLYHARLWLHVPPSFPGTLYLRIFRCGTTRCRGFRTFLAEHQTTSSGWHALTLPSSGLRSEDSGVVKLQLEFRPLDLNSTAAGLPRLLLDTAGQQRPFLELKIRANEPGAGRARRRTPTCEPETPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAGSSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS", "length": 350 }, "evidence": [ { "id": "E1BFT5", "url": "https://omabrowser.org/oma/group/E1BFT5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O88959-1", "protein_name": "Inhibin beta E chain", "gene_name": "Inhbe", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLSNVQLWTILLWALAWVQSTRSACPSCGAPTLTPQGERALVLELAKQQILEGLHLTSRPRITRPLPQAALTRALRRLQPRSMVPGNREKVISFATSIDKSTSTYRSVLTFQLSPLWSHHLYHARLWLHVPPSFPATLYLRIFGCGTTRCRGSRTFLAEHQTTSSGWHALTLPSSGLRSEESGVTKLQLEFRPLDLNSTTARLPRLLLDTAGQQRPFLELKIRANEPGAGRARRRTPTCESETPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAGSSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS", "length": 350 }, "evidence": [ { "id": "E1BFT5", "url": "https://omabrowser.org/oma/group/E1BFT5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P58166-1", "protein_name": "Inhibin beta E chain", "gene_name": "INHBE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSRPRITHPPPQAALTRALRRLQPGSVAPGNGEEVISFATVTDSTSAYSSLLTFHLSTPRSHHLYHARLWLHVLPTLPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNLGWHTLTLPSSGLRGEKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS", "length": 350 }, "evidence": [ { "id": "E1BFT5", "url": "https://omabrowser.org/oma/group/E1BFT5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BFT5", "url": "https://www.uniprot.org/uniprotkb/E1BFT5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": 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"https://www.uniprot.org/uniprotkb/E1BFU9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DENND1C", "url": "https://www.uniprot.org/uniprotkb/E1BFU9", "locus": { "chromosome": "7", "start_pos": 18006884, "end_pos": 17996518, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000031809", "url": "https://www.ensembl.org/id/ENSBTAG00000031809" } ] } } ], "crossref": [ { "id": "E1BFU9", "url": "https://alphafold.ebi.ac.uk/entry/E1BFU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000031809", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000031809", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "511230", "url": "https://www.ncbi.nlm.nih.gov/gene/511230", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511230", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511230", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QQECRTD", "url": "https://omabrowser.org/oma/group/QQECRTD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFU9", "url": "https://www.orthodb.org/?gene=E1BFU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13196:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13196:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001180093", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180093", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BFU9", "url": "https://www.uniprot.org/uniprotkb/E1BFU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFU9-1", "url": "https://www.uniprot.org/uniprotkb/E1BFU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSTAEGGPPALFDWFFEAAYPASLQEDPPILRQFPPDFQDQESMQMVPKFCFPFDVERETPSTAVQHFTFVLTDLTGTRRFGFCRLRAGALSCLCILSHLPWFEVFYKLLNTVGDLLAQDQVSEVDELLLNLLQQPLPGTQASVGLELGSGVRIASAEGLQSPVPGKNMSLSCFVAPDSSRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTSSKLSTLTSCVHASCALLYPMHWEHVLIPTLPPHLLDYCCAPMPYLIGVHASLAERVREKALEDVVILNVDSNTLETPFDDVQALPPDVVSLLRLRLRKVALAPGEGVSRLFLKAQALLFGGYRDALVCSPGQPVTFSEEAFLAQKPGAPLQAFHRRAVHLQLFKQFIEGRLEKLNTGEGFSDLFEQEITCSGASSGTLRSYQLWADNLKKGGGALLHSVKAKTQPAVRNMYRSAKSGLKGMQSLLMYKEGDSGLQRGGSLRAPSLTSRSDRLQQRLPITQHFGQNRPLRPRSRPSRRLRLEEKPSESLEERTPSLSPEDAQDPWAEEALDGSFLGSGEELDLLSEILDSLSTRATRTGSLRPSQSLDCCHREDLDSCLSLPDIPGRSSWQADDDKPPEPQHLSLLPLHTPQPLGATSSRKHPTCQLPSETGPEIESPSQSLTASADPSSKGDPGSSPTEPQPPHFSPPHEATEDPTAQEDPCSQLLAAPSQPSPPESPRPEPNLGVTWTSQALDSVSDPGSSENPGASPSEGLLAVHLQPLEEPEAPRSPAAPASNWQEPQARSGPRVAELKKCFEG", "length": 798, "header": "tr|E1BFU9-1|E1BFU9_BOVIN Isoform 1 of DENN domain containing 1C OS=Bos taurus OX=9913 GN=DENND1C PE=4 SV=1 CANONICAL=E1BFU9-1" }, "isoforms": [ { "isoform_ac": "E1BFU9-1", "url": "https://www.uniprot.org/uniprotkb/E1BFU9/entry#E1BFU9-1", "sequence": { "sequence": "MGSTAEGGPPALFDWFFEAAYPASLQEDPPILRQFPPDFQDQESMQMVPKFCFPFDVERETPSTAVQHFTFVLTDLTGTRRFGFCRLRAGALSCLCILSHLPWFEVFYKLLNTVGDLLAQDQVSEVDELLLNLLQQPLPGTQASVGLELGSGVRIASAEGLQSPVPGKNMSLSCFVAPDSSRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTSSKLSTLTSCVHASCALLYPMHWEHVLIPTLPPHLLDYCCAPMPYLIGVHASLAERVREKALEDVVILNVDSNTLETPFDDVQALPPDVVSLLRLRLRKVALAPGEGVSRLFLKAQALLFGGYRDALVCSPGQPVTFSEEAFLAQKPGAPLQAFHRRAVHLQLFKQFIEGRLEKLNTGEGFSDLFEQEITCSGASSGTLRSYQLWADNLKKGGGALLHSVKAKTQPAVRNMYRSAKSGLKGMQSLLMYKEGDSGLQRGGSLRAPSLTSRSDRLQQRLPITQHFGQNRPLRPRSRPSRRLRLEEKPSESLEERTPSLSPEDAQDPWAEEALDGSFLGSGEELDLLSEILDSLSTRATRTGSLRPSQSLDCCHREDLDSCLSLPDIPGRSSWQADDDKPPEPQHLSLLPLHTPQPLGATSSRKHPTCQLPSETGPEIESPSQSLTASADPSSKGDPGSSPTEPQPPHFSPPHEATEDPTAQEDPCSQLLAAPSQPSPPESPRPEPNLGVTWTSQALDSVSDPGSSENPGASPSEGLLAVHLQPLEEPEAPRSPAAPASNWQEPQARSGPRVAELKKCFEG", "length": 798, "header": "tr|E1BFU9-1|E1BFU9_BOVIN Isoform 1 of DENN domain containing 1C OS=Bos taurus OX=9913 GN=DENND1C PE=4 SV=1 CANONICAL=E1BFU9-1" }, "locus": { "chromosome": "7", "start_pos": 18005880, "end_pos": 17996589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045088.6", "url": "https://www.ensembl.org/id/ENSBTAT00000045088.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042504.3", "url": "https://www.ensembl.org/id/ENSBTAP00000042504.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511230", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511230", "resource": "KEGG Pathway" }, { "id": "R-BTA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BFQ0-1", "protein_name": "DENN domain-containing protein 1B isoform X1", "gene_name": "dennd1c", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSRIKKNPDKTFYWFFQASCPIARDKDPDVLFQFPEDFNDEESRKSLPRFCFPYDIERVKDSVAVQHFTFVLTDLEGCQRFGFCRLTSSSQTCLCILSYLPWFEVFYKLLNNLAECSSKGQTNEMTELLSALYKHPVPPANGSITLQMGAKLMIGSEMPGICGHAPKGEESAGIPYFIAPDPKALPSIPESRNLTELVVAVDVGNLLQLYASMLFERRILIYCSKLSTLTACVHACNGMLFPMYWQHIFIPVLPPHLLDYCCAPMPYLIGIHSSLAERVKSRALEDVVILNIDTNTLESPHEDLKKIPADVVAGLKVRLKRQAAAAGSGVAHAFLRAQALLFGGYRDALQAPADGPVVFCTELFLNHKSPSMREFLESAVHLQCFKEFIDGRLEMLNEGKEPSDVFEEELLQCGASSGGAKLCRQWVGNLKKGGGALIVTWKSTANKATKYHSKFGLKNLLSSKDQPEACTLQRGGSVCEPHTYRLIQSDCLQNRLPITQHFGKSRPRRPAQKHHRQKEQKTPVNNTTYEDSAADAVDQCSGSSDVQEEEEEDFSLLADAEEMDLLGEIFDTLSAQSSREPGLLYGTRSLDLFRSDSSEFISHKGLANPSQESLSPSFANSGSLMSWEEELEEGPDGEGEGPGGGEEEGTVNEEKGTFNEEEESIIMIDGSENELNELEKDLTELGETLRSDLQDLEDASVESSQEVQENTQDYTQMNGTMEESLDTETIAEERTETQTDKEEEELQNETPDASNGHTHEESISLKVKIDQREEPEEKSAEAQLPKVSSTVALFQSKVLVDSPVCRGKENSPKSPLRSLKINVGSAKAMQSEEECTKSPVTSNAEEQEQAPVKVSELKKRFEH", "length": 864 }, "evidence": [ { "id": "E1BFU9", "url": "https://omabrowser.org/oma/group/E1BFU9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SBS9-1", "protein_name": "DENN domain containing 1C", "gene_name": "DENND1C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSTAEGDPPAVFDWFFEAAYPASLQEDPPILRQFPPDFRDREAMQMVPKFCFPFDVEREPPSSAVQHFTFALTDLTGTRRFGFCRLRAGAHSCLCILSHLPWFEVFYKLLNTVGDLLAQDQVSEVEELLLNLLQQPLPGTPGLELGSEVTTSRAHAIPPPAPGKSKPLSCFVAPDSGRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLISSKLSTLTSCVHASCALLYPMHWEHVLIPTLPPHLLDYCCAPMPYLIGVHASLAERVREKGLEDVVMMNVDSNTLETPFDDVQALPPDVVSLLRLRLRKVALAPGEGVSRLFLKAQALLFGGYRDALVCSPGQPVTFDEKAFLAQKPGAPLQAFHQRAVHLQLFKQFIEGRLEKLNKGEGFSDLFEQEITCSCASSGTLRSYQLWADNLKKGGGALLHSVKAKTQPAVRNMYRSAKSGLKGVQSLLMYKDGDSGLQRGGSLRTPSLTSRSDRLQQRLPITQHFGQNRPLRPSRRLRLEERPSESLGEGTPPLSPGDAQEPWAEEALDGSFLGSGEELDLLSEILDSLSTRATRTSSLRPSQSLDCCHRGDPDSCFSLPDLSGRPRWQADDETPPEPRPLSLPVSPPSLHTPQLLDAGTSSEHPISQLPPEASGEIASPSGPSTASADPSSKGDSVSSLTEPQSLTLHLSPPHKASEDPIAQENPSSQLSTQPHPPESPQRPVPTKPNSDTTWTSQPLDSSSDPGSPENPRAQPSEVLQVEHTHLQPPKELGGPGRPASTWQEPATRSRPRVSELKKCFEA", "length": 797 }, "evidence": [ { "id": "E1BFU9", "url": "https://omabrowser.org/oma/group/E1BFU9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0RBQ8-1", "protein_name": "DENN domain containing 1C", "gene_name": "Dennd1c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSTEIRHPSAVFDWFFEAGRPNSLEEDPLILRKFPPDFQEQEAMQMVPRFCFPFDIEREPPSPAVQHFTFALTDLVGNRRFGFCRLRAGAWSCLCILSHLPWFEVFYKILNTVGDLLAQNQVTEAEELLQNLQQHPYLGPGFSGGPKTDSSITSWSECGILPPALGNSKLLSCFVAPDAAGLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTACVHASCALLYPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHSSLAERVREKALEDVVVLNADSNTLETPFDDVQALPPDVVSLLRLRLRKVALSPGEGVSRLFLKAQALLFGGYRDALVCIPGQPVTFSEEAFLAQKPGAPLQAFHKKAVHLQLFKQFIESRLEKLNAGEGFSDQFEQEIIACCGASSGTLRSYQLWADSLKKGSDALLHSVKAKTRPAVRNMYRSAKSGLKGMQNLLMIKDGDSCLQRGGSLRTPSLTSRSDRLQQRLPISQHFGQNRPLRPSRRLKPEGGPSEPLQERSPTLNSRDTQNPWAEDTLDGSFLGSGEELDLLSEILDSLSVEIKSGGQLRASQSLDCCQQGASESCSSLPDIPVGSPWQLEEDRRSQDPQLQSLPGDLSPLQDTPFSEVVSYSKNCPQPPSDISSLPTSSATSADPPSQRDPGPSSSSKLDPTPSQSPCSRTLRVPTQPTPPKSQLLASTEPNSDTVQKLQPIQSPLCSQSKENPRNQPPQVLLSQACIQPLKELGAPTSYVSHVGKHQEPQDRQPRVADLKKCFEN", "length": 786 }, "evidence": [ { "id": "E1BFU9", "url": "https://omabrowser.org/oma/group/E1BFU9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CFK6-1", "protein_name": "DENN domain-containing protein 1C", "gene_name": "Dennd1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSTETRHPPAMFDWFFEAGCPNSLEEDPPILRQFPPDFQEQEAMQMVPRFCFPFDIEREPPSPAVQHFTFALTDLVGNRRFGFCRLRAGARSCLCILSHFPWFEVFYKILNNVGDLLAQNQVAEAEELLQNLQQHPLLGPRFSGRSEMDSSITVRSECGILPPALGNSKLLSCFVAPDAASLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTACVHASCALLYPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHGSLAERVREKALEDVVVLNADSNTLETPFDDVQALPPDVVSLLRLRLRKVALSPGEGVSRLFLKVQALLFGGYRDALVCIPGQPVTFSEEAFLAQKPGAPLQAFHKKAVHLQLFKQFIESRLEKLNAGEGFSDQFEQEIIACRGASSGTLRSYQLWVDSLKKGSDALLHSMKTKTQPAVRNMYRSGDSLQEYCASKAKSGLKGMQNLLTIKDGDSGLQRGGSLRTPSLTSRSDRLQQRLPISQHFGQNRPLRPSRRLKTEEGPSEPLRERSPTLSPGDTQNPWAEDTLDGSFLGSGEELDLLSEILDSLNVETKSGDLQRASQSLDCCQRGAASESCSSLPDIPVGLPWQLEEDKRSQDPQPWSLPGDLSLLQDTPFSEVVSYSKNSCSQPFQQSPPSQGDPGPSLSKLDPRPSQSPCPKLLRVPTRHSPPESPQLLVSTEPNSDAVQRLQSISSPSCSHSAENPRNQPPQVLLGQACVQPLEELGAPTYVSHVSTQQRPQDKQPRVADLKKCFEN", "length": 786 }, "evidence": [ { "id": "E1BFU9", "url": "https://omabrowser.org/oma/group/E1BFU9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IV53-1", "protein_name": "DENN domain-containing protein 1C", "gene_name": "DENND1C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESRAEGGSPAVFDWFFEAACPASLQEDPPILRQFPPDFRDQEAMQMVPKFCFPFDVEREPPSPAVQHFTFALTDLAGNRRFGFCRLRAGTQSCLCILSHLPWFEVFYKLLNTVGDLLAQDQVTEAEELLQNLFQQSLSGPQASVGLELGSGVTVSSGQGIPPPTRGNSKPLSCFVAPDSGRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTSCVHASCALLYPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHASLAERVREKALEDVVVLNVDANTLETTFNDVQALPPDVVSLLRLRLRKVALAPGEGVSRLFLKAQALLFGGYRDALVCSPGQPVTFSEEVFLAQKPGAPLQAFHRRAVHLQLFKQFIEARLEKLNKGEGFSDQFEQEITGCGASSGALRSYQLWADNLKKGGGALLHSVKAKTQPAVKNMYRSAKSGLKGVQSLLMYKDGDSVLQRGGSLRAPALPSRSDRLQQRLPITQHFGKNRPLRPSRRRQLEEGTSEPPGAGTPPLSPEDEGCPWAEEALDSSFLGSGEELDLLSEILDSLSMGAKSAGSLRPSQSLDCCHRGDLDSCFSLPNIPRWQPDDKKLPEPEPQPLSLPSLQNASSLDATSSSKDSRSQLIPSESDQEVTSPSQSSTASADPSIWGDPKPSPLTEPLILHLTPSHKAAEDSTAQENPTPWLSTAPTEPSPPESPQILAPTKPNFDIAWTSQPLDPSSDPSSLEDPRARPPKALLAERAHLQPREEPGALNSPATPTSNCQKSQPSSRPRVADLKKCFEG", "length": 801 }, "evidence": [ { "id": "E1BFU9", "url": "https://omabrowser.org/oma/group/E1BFU9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BFU9", "url": "https://www.uniprot.org/uniprotkb/E1BFU9" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "E1BFU9", "url": "https://www.uniprot.org/uniprotkb/E1BFU9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "E1BFU9", "url": "https://www.uniprot.org/uniprotkb/E1BFU9" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "E1BFU9", "url": "https://www.uniprot.org/uniprotkb/E1BFU9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E1BFU9", "url": "https://www.uniprot.org/uniprotkb/E1BFU9" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate binding", "id": "GO:1901981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901981", "evidence": [ { "database": "UniProtKB", "id": "E1BFU9", "url": "https://www.uniprot.org/uniprotkb/E1BFU9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" } ], 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BFV8-1", "uniprot_ac": "E1BFV8", "uniprot_id": "E1BFV8_BOVIN", "mass": { "chemical_mass": 64965.0, "monoisotopic_mass": 64965.0 }, "refseq": { "ac": "XP_024841834", "name": "carbohydrate sulfotransferase 15 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841834" }, "gene_names": [ { "name": "CHST15", "type": "recommended", "evidence": [ { "id": "E1BFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV8" } ] }, { "name": "CHST15", "type": "synonym", "evidence": [ { "id": "XP_024841834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841834" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "E1BFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV8/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "E1BFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV8/entry#names_and_taxonomy" } ] }, { "name": "carbohydrate sulfotransferase 15 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024841834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841834" } ] } ], "function": [ { "annotation": "Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.", "evidence": [ { "database": "UniProtKB", "id": "E1BFV8", "url": "https://www.uniprot.org/uniprotkb/E1BFV8#function" }, { "database": "UniProtKB", "id": "ARBA00059303", "url": "https://www.uniprot.org/uniprotkb/ARBA00059303#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFV8", "url": "https://www.uniprot.org/uniprotkb/E1BFV8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CHST15", "url": "https://www.uniprot.org/uniprotkb/E1BFV8", "locus": { "chromosome": "26", "start_pos": 43713869, "end_pos": 43748427, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003312", "url": "https://www.ensembl.org/id/ENSBTAG00000003312" } ] } } ], "crossref": [ { "id": "E1BFV8", "url": "https://alphafold.ebi.ac.uk/entry/E1BFV8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003312", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003312", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "534506", "url": "https://www.ncbi.nlm.nih.gov/gene/534506", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534506", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534506", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKQQVGC", "url": "https://omabrowser.org/oma/group/HKQQVGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFV8", "url": "https://www.orthodb.org/?gene=E1BFV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15723:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15723:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022870", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2022923", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022923", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024841834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841834", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "54300", "url": "https://www.rhea-db.org/rhea/54300", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54304", "url": "https://www.rhea-db.org/rhea/54304", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BFV8", "url": "https://www.uniprot.org/uniprotkb/E1BFV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFV8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRHCINCCIQLSPDDVQTQQVSCRGSSHHGRQECPVCKAENKIVFRVDGKQMNLLAVLEVRADGNESWGGFLRFKKGKRCSLIFGLIIMTLVMASYILSGVHQELLISSPFHYGAFPSNPSLMEGENPSDAKEHHHQSSVNNISYMKDYPSIKLIINSITSRIEFTTRQLPDVEDLKKQELHMFSVIPHKFLPNSKSPCWYEEFTGRNTTDPYLTNSYVLYSKRFRSTFDTLRKAFWGHLSHAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVEDYLDLFDLAAHQIHQGLQASAAKEPSKMNRIIIGEASASTMWDNNAWTLFYDNGTDGEPPFLTQDFIHAFQPDAKLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLTVFNKEQFLILRLEDHASNVKDTMHRVFQFLSLGPLSEKQEALMTKSPASNTRRPEDRDLGPMWPVTQRLLRDFYGPFNARLAQVLADEAFLWRKT", "length": 561, "header": "tr|E1BFV8-1|E1BFV8_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=CHST15 PE=3 SV=1 CANONICAL=E1BFV8-1" }, "isoforms": [ { "isoform_ac": "E1BFV8-1", "url": "https://www.uniprot.org/uniprotkb/E1BFV8/entry#E1BFV8-1", "sequence": { "sequence": "MRHCINCCIQLSPDDVQTQQVSCRGSSHHGRQECPVCKAENKIVFRVDGKQMNLLAVLEVRADGNESWGGFLRFKKGKRCSLIFGLIIMTLVMASYILSGVHQELLISSPFHYGAFPSNPSLMEGENPSDAKEHHHQSSVNNISYMKDYPSIKLIINSITSRIEFTTRQLPDVEDLKKQELHMFSVIPHKFLPNSKSPCWYEEFTGRNTTDPYLTNSYVLYSKRFRSTFDTLRKAFWGHLSHAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVEDYLDLFDLAAHQIHQGLQASAAKEPSKMNRIIIGEASASTMWDNNAWTLFYDNGTDGEPPFLTQDFIHAFQPDAKLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLTVFNKEQFLILRLEDHASNVKDTMHRVFQFLSLGPLSEKQEALMTKSPASNTRRPEDRDLGPMWPVTQRLLRDFYGPFNARLAQVLADEAFLWRKT", "length": 561, "header": "tr|E1BFV8-1|E1BFV8_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=CHST15 PE=3 SV=1 CANONICAL=E1BFV8-1" }, "locus": { "chromosome": "26", "start_pos": 43748228, "end_pos": 43714873, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004287.6", "url": "https://www.ensembl.org/id/ENSBTAT00000004287.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004287.4", "url": "https://www.ensembl.org/id/ENSBTAP00000004287.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:534506", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534506", "resource": "KEGG Pathway" }, { "id": "R-BTA-2022870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "resource": "Reactome", "description": "CS-GAG biosynthesis" }, { "id": "R-BTA-2022923", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022923", "resource": "Reactome", "description": "DS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480DSI2-1", "protein_name": "Sulfotransferase", "gene_name": "CHST15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRHCINCCIQLSPDDTHAQQVNCRGGPHHSRQECPACKGENTIVFRVDGKQMNLLAVLEVRAEGNESWGGFLRFKKGKRCSLVFGLVIMTLVLASYILSGVHQELISSPFHYGAFPSNPGSTDGENLSDTKEPHHPPSVNNISYVKDYPSIKLIINSITARIEFTTRQLPDREDLKKQELHMFSVIPGKFLPNCKSPCWYEAFAGRNTTDPYRTNSYALYSKRFRSTFDTLRKAFWGHLSHAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVEDYLDLFDLAAHQIHQALQASSAKEQSKMNRILIGEASASTMWDNNAWTLFYDNSSDGEPPFLTQDFIHAFQPDAKLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLTVFDKEQFLILRLEDHASNVKFTMHRVFQFLSLGPLTEKQEALLTKSPASNARRPEDRNLGPMWPVTQRILQDFYGPFNARLAQVLADEAFLWKKT", "length": 560 }, "evidence": [ { "id": "E1BFV8", "url": "https://omabrowser.org/oma/group/E1BFV8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XD49-1", "protein_name": "Sulfotransferase", "gene_name": "CHST15", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRHCINCCIHLLPNDLHRQCFRCRGHSHNNQKCPVCKGENRIPLYADSKQMKLLAVLEVRTDHSESWNGFFCLKKGKLCSLIFGLIIMTLVMASYVLTGAKHGLLLIPSPFHYGAFTSNPSLMDNESLSDMKDHYQPSKINISYIKDYPSIKLIIDTITSKIEFITRQRPGLELLRKQEPHMFSVIPNKFLPNSKNPCWYEEYRGNTTTDPYTTNSYALYSKRFRTIFDYLRKVFWNHLYHYKDKHYRLRCLPHFYIIGQPKCGTTDLYDRLRLHPDVRFSAIKEPHWWTRKRFGIIRLRDGFHDRYPVEDYLDLFDLAAHQIQGVLQSEAAKEHSEMNNIIIGEASASTMWDNNAWIFFYDNSSEGEPPFLIQDFIHAFQPNAKLIIMLRDPVERLYSDYLYFASANKSAEDFHEKVAESLQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYVVYLLDWLTVFDKDQILVLRLEDHASNVKYTMHMVFQFLDLGPLSEKQEALITKSPASNTRRPEDRSLGPMLPTTKAILRDFYRPFNTKLAQVLFDDAFLWKRT", "length": 560 }, "evidence": [ { "id": "E1BFV8", "url": "https://omabrowser.org/oma/group/E1BFV8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q7LFX5-1", "protein_name": "Carbohydrate sulfotransferase 15", "gene_name": "CHST15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRHCINCCIQLLPDGAHKQQVNCQGGPHHGHQACPTCKGENKILFRVDSKQMNLLAVLEVRTEGNENWGGFLRFKKGKRCSLVFGLIIMTLVMASYILSGAHQELLISSPFHYGGFPSNPSLMDSENPSDTKEHHHQSSVNNISYMKDYPSIKLIINSITTRIEFTTRQLPDLEDLKKQELHMFSVIPNKFLPNSKSPCWYEEFSGQNTTDPYLTNSYVLYSKRFRSTFDALRKAFWGHLAHAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVEDYLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKVFQFLNLGPLSEKQEALMTKSPASNARRPEDRNLGPMWPITQKILRDFYRPFNARLAQVLADEAFAWKTT", "length": 561 }, "evidence": [ { "id": "E1BFV8", "url": "https://omabrowser.org/oma/group/E1BFV8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CHI9-1", "protein_name": "Carbohydrate sulfotransferase 15", "gene_name": "Chst15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHCINCCIQLFPEDAHKQQVACQGGPHHSHQACPSCKGEDKILFRVDSKQMNLLAVLEVRTEGNENWGGFLRFRKGKRCSLVFGLIIMTLVMASYILSGAHQELLISSPFHYGGFPSNPSVMDSESPSDVKEHHYQPSVNNISYVKDYPNIKLIIDSIAARNEFTTRQLPDLQDLKRQELHMFSVIPNKFLPTSKSPCWYEEFSGRNTTDPYLTNSYVLYSKRFRSTFDTLRKAFWGHLSHVHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVEDYLDLFDLAAHQIHQGLQAASAEQTSKMNRIIIGEASASTMWDNNAWTFFYDNSTDGEPPFLTQDFIHAFQPEAKLLVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLTVFSKEQFLILRLEDHASNVKYTMHKVFQFLNLGPLSEKQEALMTKSPASNTRRPEDRSLGPMWPITQKILRDFYGPFNTRLAQVLDDEAFAWKTT", "length": 561 }, "evidence": [ { "id": "E1BFV8", "url": "https://omabrowser.org/oma/group/E1BFV8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91XQ5-1", "protein_name": "Carbohydrate sulfotransferase 15", "gene_name": "Chst15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRHCINCCVQLFPEDTHKQQVACQGGPHHSHQACPTCKGENKILFRVDSKQMNLLAVLEVRTEGNENWGGFLRFRKGKRCSLVFGLIIMTLVMASYILSGAHQELLISSPFHYGGFPSNPSVMDGENPSDVKEHHYQPSVNNISYVKDYPSIKLIIDSIAARIEFTTRQLPDLQDLKRQELHMFSVIPSKFLPTSKSPCWYEEFSGRNTTDPYLTNSYVLYSKRFRSTFDALRKVFWGHLSHVQGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVEDYLDLFDLAAHQIHQGLQAASAEQPSKMNKIIIGEASASTMWDNNAWTFFYDNSTDGEPPFLTQDFIHAFQPEAKLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLTVFSKEQFLILRLEDHASNVKYTMHKVFQFLNLGPLSEKQEALMTKSPASNTRRPEDRSLGPMWPITQKILREFYGPFNTRLAQVLDDEAFAWKTT", "length": 561 }, "evidence": [ { "id": "E1BFV8", "url": "https://omabrowser.org/oma/group/E1BFV8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "hexose biosynthetic process", "id": "GO:0019319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019319", "evidence": [ { "database": "UniProtKB", "id": "E1BFV8", "url": "https://www.uniprot.org/uniprotkb/E1BFV8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "3'-phosphoadenosine 5'-phosphosulfate binding", "id": "GO:0050656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050656", "evidence": [ { "database": "UniProtKB", "id": "E1BFV8", "url": "https://www.uniprot.org/uniprotkb/E1BFV8" } ], "pmid": "" }, { "name": "N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity", "id": "GO:0050659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050659", "evidence": [ { "database": "UniProtKB", "id": "E1BFV8", "url": "https://www.uniprot.org/uniprotkb/E1BFV8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BFV8", "url": "https://www.uniprot.org/uniprotkb/E1BFV8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "54300", "name": "", "equation": "chondroitin 4'-sulfate + n 3'-phosphoadenylyl sulfate = chondroitin 4',6'-bissulfate + n adenosine 3',5'-bisphosphate + n H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BFV8-1" ], "evidence": [ { "id": "54300", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54300" } ] }, { "id": "54304", "name": "", "equation": "dermatan 4'-sulfate + n 3'-phosphoadenylyl sulfate = dermatan 4',6'-bissulfate + n adenosine 3',5'-bisphosphate + n H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BFV8-1" ], "evidence": [ { "id": "54304", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54304" } ] }, { "id": "R-BTA-2018659", "name": "CHST15 transfers sulfate to (6-)GalNAc-4-sulfate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BFV8-1" ], "evidence": [ { "id": "R-BTA-2018659", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2018659" } ] }, { "id": "R-BTA-9941312", "name": "CHST15 transfers sulfate to (6-)GalNAc-4-sulfate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BFV8-1" ], "evidence": [ { "id": "R-BTA-9941312", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9941312" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BFV8", "gene_name": "CHST15", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV8" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BFV8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 561, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BFV8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BFV8" } ], "lectin_list": [], "domain_list": [ 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG09-1", "uniprot_ac": "E1BG09", "uniprot_id": "E1BG09_BOVIN", "mass": { "chemical_mass": 247417.0, "monoisotopic_mass": 247417.0 }, "refseq": { "ac": "XP_005224096", "name": "rotatin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224096" }, "gene_names": [ { "name": "RTTN", "type": "recommended", "evidence": [ { "id": "E1BG09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG09" } ] }, { "name": "RTTN", "type": "synonym", "evidence": [ { "id": "XP_005224096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224096" } ] } ], "protein_names": [ { "name": "Rotatin", "type": "recommended", "evidence": [ { "id": "E1BG09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG09/entry#names_and_taxonomy" } ] }, { "name": "rotatin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005224096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224096" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG09", "url": "https://www.uniprot.org/uniprotkb/E1BG09" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RTTN", "url": "https://www.uniprot.org/uniprotkb/E1BG09", "locus": { "chromosome": "24", "start_pos": 7239738, "end_pos": 7121400, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013221", "url": "https://www.ensembl.org/id/ENSBTAG00000013221" } ] } } ], "crossref": [ { "id": "ENSBTAG00000013221", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013221", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "615378", "url": "https://www.ncbi.nlm.nih.gov/gene/615378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FCKCVGL", "url": "https://omabrowser.org/oma/group/FCKCVGL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BG09", "url": "https://www.orthodb.org/?gene=E1BG09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31691", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31691", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31691:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31691:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14726", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14726", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005224096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224096", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BG09", "url": "https://www.uniprot.org/uniprotkb/E1BG09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG09-1", "url": "https://www.uniprot.org/uniprotkb/E1BG09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLTGLIRKLGHPLAEIRERALRSILCKLEHSLVCGADLASHRLLFLHLLEWFNFPSVPVKDEVLGLLSRLVKYPLAVQHLVDLGAVEFLSKLRPNVEPNLQAEIDGILDGLFSLPSEVPEMYSSSYQTSQTDLLQQPEILTGYFPQDKSTLQQTEIPSRPVAANPTAKCLKFSTFPWLPLTAADRHVLSSNESSLRSSNHTVIWNTCELLKDVIMQDFPAEIFLQRPKIVQSLLSLLKLAFGGDGKHRLALQSVSCLQQLCTCLRNRLNFHRDPSFFSNKQDAVSQNSSLSYCPDARAAPHSQNPSPGSSSPRPSVVGRTGQRPRGDGQDWDAVSSSGSSSHAHVSSRASAPSPLDLAPVDLPELAEDALELQLQQLSLPQLCVSLLEAAAPLLRTGSRQMIIRVLELLAEVVVLIGEAISAHLWDDSSLFAIDMKEKLLVVLASLGDTVCYHKSCVSLEQPEALVVHHRMAFVSISLFAVRLLQTLLPVEKASRFLPEPMLAALFFISLDMPVSLEYPNIHEAVVAYLEQLNSENYSIYKRTAEAAYSIECTCNFLSDVGKEGEKNLSELVELADQALRSFSYHQHFPLIKEIISICSKIWKSVQASPLLQGESQKVFLRMLSHPLLQVKVETYHCCLEIVKECLGIHNISKPVSSLCNGIHFLLHPKVLYEISAFGIQDPKNEVSAAAKAILVHLLQGRLRVSAPTWNKFIESLCPVIPVLQGYADTEDPLGNCILHLSRESPETDEGVLPSATRLKSMLRLLLVKKPSVRVLALKLLASHLTREEGSDTKRPSIDARVLSRVTNLFIVKKPIELKLDDRRELMIKLETVEKVYGIFVSDDVDLVLRKSAAEQLVVIMQDIKMHAVVKKVHLVDKIIEYLSECVGQDGEVVECLVQPSLMLLRKVLCADPVLRESLSQKTSVLTLLFRVSLIFHEDCTIVTEVGALFCLLLFDEVSRMDMWSDSPSCTPSSPSVFSLPVSVSRRYHLPVHVVGHHAVSPYSMVLPLSADSLALKPVSDMLRMAWNLSWYHGSDNVLKQVNSEAEIQEFLDTLKLSTEDTLTLKMTHTPSGLKDCLCSIVQAAGHREVRAALTRMSFYLLNDRLSFKGGTGPCGVTLKSLSWHTTLNRFLQVLPACTEDEKLLIDIIHFLSKLLKEQRKNVPVELLNWLLEVLLRQSPNPLLDLLVLTESQTREETDDVRTAVRQQLQKELIALFSTLLLSFEAVTDRKCLELFYVFQTQLALKLLQCLRVTDAPHFYGLPSLERTLRGMAHLTACPGWSTHSPLTKPLDICGKYLSGLLEVITSFYVERGGNAMSFMGKGVTKSTVLCLLHLSHEMMAQAQSSGWMSLWFLPLGSQSEDHAPTQQGLAWLIPLWVDRDPEVRFTSLGLGSALTTLETGCVALANSCQNISGGLWGTVVNILLDQSECSMVRREAAFIFQNLLVIPMPSVIIKDYTWQGPCVHDEDSGLSLIGKPALQALLYHCHFYEHLNQMVKHCYLGRYAFDFSFSALNGAPEGNDLNGLDDSFKFWRAPSRMSSQDRDPSSLSTSETMVAASSGSAEFQSLVLSMVPHPEVTHDQLVAQGQREAASPRLPPDSPLSAPLPRQCVFVTPPLLSAMCSLLDSLLVATPGDTAGAFRRTRLIELLCSIAVATLLETSVQELRASLPTSLPAEHTQAQVSFLLEYLSSLSRLLQSCLLVDPDLVIQDELLKPLIPNIIRVLTLCTKDILDVELRSAFYQTWTHLFNLLAALLRRAGPASFPYVTLGLARSWAAVIDTFCRCARLSTTSPALYTASLQFLSVLLTEEAKRRLQDEEKTSLCHSPTVASLLDKTQESQNSLERLTEVILQCYEGKTSKDVLKRVAANALMSLLAVSRRAQRHALKAHLVDSCVEQMKHIHAQLNLGSLKPGRAVLRKKEDGFIKELSIAMQLLRNCLYQNEECKGAALDAHLAPVLHALWPWLLMDDSLMQVALQLLCVYTANFPNGCSSLCWSSYGQHPVQAAHRGAPGSSLMLCILKMASQVPPENTAVQQAVFMILSNLALSHDCKGVIQKSNFLQNFLSLTLPKGGNKHLSNLSVLWLKLLLNMSFEEDGQQVILRLDGCLDLLTEMSRFKHKSSLSIPLLIFHNICFSPANKPKILANEKVISVLAACLESENQNAQRIGAAALWALIHNYQKAKTTLKNPSIKRRVEEAYSLAKKTFSDSEETPLSAYYLKCLENLVQQLNSS", "length": 2229, "header": "tr|E1BG09-1|E1BG09_BOVIN Isoform 1 of Rotatin OS=Bos taurus OX=9913 GN=RTTN PE=3 SV=3 CANONICAL=E1BG09-1" }, "isoforms": [ { "isoform_ac": "E1BG09-1", "url": "https://www.uniprot.org/uniprotkb/E1BG09/entry#E1BG09-1", "sequence": { "sequence": "MVLTGLIRKLGHPLAEIRERALRSILCKLEHSLVCGADLASHRLLFLHLLEWFNFPSVPVKDEVLGLLSRLVKYPLAVQHLVDLGAVEFLSKLRPNVEPNLQAEIDGILDGLFSLPSEVPEMYSSSYQTSQTDLLQQPEILTGYFPQDKSTLQQTEIPSRPVAANPTAKCLKFSTFPWLPLTAADRHVLSSNESSLRSSNHTVIWNTCELLKDVIMQDFPAEIFLQRPKIVQSLLSLLKLAFGGDGKHRLALQSVSCLQQLCTCLRNRLNFHRDPSFFSNKQDAVSQNSSLSYCPDARAAPHSQNPSPGSSSPRPSVVGRTGQRPRGDGQDWDAVSSSGSSSHAHVSSRASAPSPLDLAPVDLPELAEDALELQLQQLSLPQLCVSLLEAAAPLLRTGSRQMIIRVLELLAEVVVLIGEAISAHLWDDSSLFAIDMKEKLLVVLASLGDTVCYHKSCVSLEQPEALVVHHRMAFVSISLFAVRLLQTLLPVEKASRFLPEPMLAALFFISLDMPVSLEYPNIHEAVVAYLEQLNSENYSIYKRTAEAAYSIECTCNFLSDVGKEGEKNLSELVELADQALRSFSYHQHFPLIKEIISICSKIWKSVQASPLLQGESQKVFLRMLSHPLLQVKVETYHCCLEIVKECLGIHNISKPVSSLCNGIHFLLHPKVLYEISAFGIQDPKNEVSAAAKAILVHLLQGRLRVSAPTWNKFIESLCPVIPVLQGYADTEDPLGNCILHLSRESPETDEGVLPSATRLKSMLRLLLVKKPSVRVLALKLLASHLTREEGSDTKRPSIDARVLSRVTNLFIVKKPIELKLDDRRELMIKLETVEKVYGIFVSDDVDLVLRKSAAEQLVVIMQDIKMHAVVKKVHLVDKIIEYLSECVGQDGEVVECLVQPSLMLLRKVLCADPVLRESLSQKTSVLTLLFRVSLIFHEDCTIVTEVGALFCLLLFDEVSRMDMWSDSPSCTPSSPSVFSLPVSVSRRYHLPVHVVGHHAVSPYSMVLPLSADSLALKPVSDMLRMAWNLSWYHGSDNVLKQVNSEAEIQEFLDTLKLSTEDTLTLKMTHTPSGLKDCLCSIVQAAGHREVRAALTRMSFYLLNDRLSFKGGTGPCGVTLKSLSWHTTLNRFLQVLPACTEDEKLLIDIIHFLSKLLKEQRKNVPVELLNWLLEVLLRQSPNPLLDLLVLTESQTREETDDVRTAVRQQLQKELIALFSTLLLSFEAVTDRKCLELFYVFQTQLALKLLQCLRVTDAPHFYGLPSLERTLRGMAHLTACPGWSTHSPLTKPLDICGKYLSGLLEVITSFYVERGGNAMSFMGKGVTKSTVLCLLHLSHEMMAQAQSSGWMSLWFLPLGSQSEDHAPTQQGLAWLIPLWVDRDPEVRFTSLGLGSALTTLETGCVALANSCQNISGGLWGTVVNILLDQSECSMVRREAAFIFQNLLVIPMPSVIIKDYTWQGPCVHDEDSGLSLIGKPALQALLYHCHFYEHLNQMVKHCYLGRYAFDFSFSALNGAPEGNDLNGLDDSFKFWRAPSRMSSQDRDPSSLSTSETMVAASSGSAEFQSLVLSMVPHPEVTHDQLVAQGQREAASPRLPPDSPLSAPLPRQCVFVTPPLLSAMCSLLDSLLVATPGDTAGAFRRTRLIELLCSIAVATLLETSVQELRASLPTSLPAEHTQAQVSFLLEYLSSLSRLLQSCLLVDPDLVIQDELLKPLIPNIIRVLTLCTKDILDVELRSAFYQTWTHLFNLLAALLRRAGPASFPYVTLGLARSWAAVIDTFCRCARLSTTSPALYTASLQFLSVLLTEEAKRRLQDEEKTSLCHSPTVASLLDKTQESQNSLERLTEVILQCYEGKTSKDVLKRVAANALMSLLAVSRRAQRHALKAHLVDSCVEQMKHIHAQLNLGSLKPGRAVLRKKEDGFIKELSIAMQLLRNCLYQNEECKGAALDAHLAPVLHALWPWLLMDDSLMQVALQLLCVYTANFPNGCSSLCWSSYGQHPVQAAHRGAPGSSLMLCILKMASQVPPENTAVQQAVFMILSNLALSHDCKGVIQKSNFLQNFLSLTLPKGGNKHLSNLSVLWLKLLLNMSFEEDGQQVILRLDGCLDLLTEMSRFKHKSSLSIPLLIFHNICFSPANKPKILANEKVISVLAACLESENQNAQRIGAAALWALIHNYQKAKTTLKNPSIKRRVEEAYSLAKKTFSDSEETPLSAYYLKCLENLVQQLNSS", "length": 2229, "header": "tr|E1BG09-1|E1BG09_BOVIN Isoform 1 of Rotatin OS=Bos taurus OX=9913 GN=RTTN PE=3 SV=3 CANONICAL=E1BG09-1" }, "locus": { "chromosome": "24", "start_pos": 7239236, "end_pos": 7121408, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017595.7", "url": "https://www.ensembl.org/id/ENSBTAT00000017595.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017595.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017595.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1613, "start_aa": "Thr", "end_pos": 1613, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1613", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 971, "start_aa": "Thr", "end_pos": 971, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr971", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A096MJA7-1", "protein_name": "Rotatin", "gene_name": "Rttn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDSAPGWIHKGPPLPGHQLTEIRERALKSILCKIEHNLICCADLIQERLLFLHLLEWFNFPSVPMKEEVLNLLSRLVKYPPAVQHLIDLGAVEFLSKLRPNVEPAIQAEIDGILDGLFILPSEVPALRSATYQPDQNELSQQPEVLTGYFPQDKSNLQQMEVPPGPVGNPTVKWLRFSVFPWLPLTTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDFPAEIFLQRPKIVQGLLCLVKLAFGGDGKHRLALQSVSCLQQLCTSLRNRLNFYRDPNLFSNKQDTISQNSSLSYCHEARGPYHSPNPSPGSSSSRPSVVGRTGQRPRGDGQDWDAVSSSGSSSHAHVNSRLSVRSPLDVAHADLPELETEDALELHFQQLSLPQFCISTLDAAVPLLRTGSREMVIRVLELLGEDLLLIGQAISSEIWDDNSLFAIDVKEKLLQVLGSLGETMCYRKTSFSLEQAEAILVHHRMAFVSISLFTVRLLQILLPVEKASEFLPESMSAALFFVSLDMPISLEYPEIHDTVVAYLEQLDSENYSIYKRTAEAVYSIECTCNFLSDVGKEGEKNLLELVELADQALRSFSYHQHSPLIKEVICLCSKIWKSAQASPLLQGESQKVFLHMLSHPLPQVKVETYQCCLEIVKECLGVHNVTKPVSSLCSGIHFLLHPKVLYEISAFGIQESKNEVNAAAKAVLLYLLQGRFMMTALTWNKFIESLCPVIPVLQGYADTEDPLGNCILLLSKVSSETGEGILPCTTRLKSVLRLLLVKKPSVRSLALKLLAFHLTGEEGADTKRPFVDARVLSRVTNLFIVKKPIDLKLDDRRELVIKLETVKKVYEIFTSDDVDLVLRKSAAEQLAVIMQDIKMHTVVKKLCLIEKIIGYLNEFVGQDGKVIECLIRPCLTLLRKVVCADLVIRASLSQQASLLTLLLRVSLIFHEDCAVVAEVGALFCLLLFDEVSRMDMWSDNSSNKPSLSSVFSLPVSVFRRYHLPVYVNGHHAVSPYSIVLPLSTECLALKPVSDMLRIAWNLAWYHGSDNLLKQTTSETKIQEFSDTLQLSTEDILTLKITYTDSGLKDCLQSIVQAGGHRDVRAAITRMSFYLLNDKLSLKDDIGPCGFTLKSLAWHTVLNRFLQVLPACTEDEKLLIDIIHFLNKLIKEQRKNPSVELLNWILELLLRHNPNPLLDLLVLTESHTREVTDEIRTAVRQQLQKELITLLNSLLLVCMTVSDRKCLELFYVFQTQLSLKLLQCLRVTDAPHFYGLPSLERTLAGMAHLTASPGWSAHSPLSKPLEICGKYLSGLLEVITSFYVERGGNAMSFMGKGVTKSTVLCLLHLSHEMIVQAPNSEWMPLWFLPLGSHSEENVPSQQGLAWLIPLWVDRDPEVRFTSLGLGSALTTMEAGCVALANSCQNISGGLWGTVVNILLDQSECSMVRREAAFILQNLLVIPMPSKVIKDYTWQGPCVHDEDSGLSLSGKPALQALLYHCRFYEHLTHMVKHCYVGRYMFDFNISAFTETSEYNDLNGLDDSFKFWRAPSGTSTQDHEPSSLSTSETMVAASVVSAEIQPLLPSTLLPEPAALDQFVTQGQPEVRPVRPRDSSPSASLHRQCVFVTPSLLSAVCSLLDNLLAVTPRDAANAFQQAHLIELLCSTMDASLLEMCVQELKTPLSLSSAVEHTQAQTSFFLEYLSSLFQLLKSCLLVDPKLVTQDELLKPLITNVIRVLIVCTKDVLDVQLVLAFHRTWTHLFDLLATLLRKAGAVSLVPLTSALAKHWEAVTDTLCRCVGLSVKCPALSIASLQFLSVLLAEEEKRRVQDKDKTNACQTPTVAFLLDGTQGSLRSSERLNETILQCYEGISSKDVLKRVAANALMSLLAVSRRAQRHALKSDLIENCVEQMKHINAQLNLDVLRPGKAALKKKEDGIIKELSITLQLLRNCLYQNEECKVAAFEAHLVPVLHSLWPWLLMEDSLMQIALQLLCVYTANFPTGCSSLCWSNYGQYIQTAHRGTPSSSLILCALKLASQVPAENTPIQQAVFMFLSNLALSHDCKGVIQKSNFLQHFLSLTLPKGGNQHLSNVTILWLKLLLNMSFGEDGQQMILRLDGCLDLLIEMSKYTHKSSPHVPLLIFHNICCSPANKPKILANEKVVTLLATCLESENQNAQRIGAASLWALTYNYQKAKATLKNPSIKRKIDEAYSIAKRTFSNSEEDPLNSYYLKCLENLVQLLNCS", "length": 2233 }, "evidence": [ { "id": "E1BG09", "url": "https://omabrowser.org/oma/group/E1BG09/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86VV8-1", "protein_name": "Rotatin", "gene_name": "RTTN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLAGLIRKLGHQLAEIRERALKSILCKIEHNLICYADLIQERQLFLHLLEWFNFPSVPMKEEVLNLLSRLVKYPPAVQHLVDVGAVEFLSKLRSNVEPNLQAEIDGILDGLFLLPSEVPALSSASYQTNQTELSKNPEILTGYFPQDKSNFQQMEVPPRPVVNQTVKCLKFSTFPWLPLTTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDFPAEIFLQRPKIVQSLLSLLKLAFGDGKHRLALQSVSCLQQLCMYLRNRLNFHRDPGFFSNKHDTVSQNSSLSYCHEARGTHHSQNPSPGSSSPRPSVVGRTGQRPRGDGQDWDAASSSGSSSHAHVNSRISVHSPLDMGHIDLPELETEDTLELQFQQLSLPQFCVSILESAVPLLRTGSRQVIIRVLELLTEDMTLIGEAISTDIWDDSSLFGIDMKEKLLLVLGALGETMCYHKSSISLEQPEVMLVHHRMAFISISLFAVRLLQTLLPVEKASEFLSEPMSTALFLLSLDMPISLEYPNIHEAVVAYLEQLNSENYSIYKRTAEAVYSIECTCNFLSDIGKEGEKNLLELVELADQALRSFSYHQHFPLIKEIISICSKIWKSAQASPLLQGESQKVLLHMLSHPLPRVKAETYHCCLEITKECLGVHNVTKPVSSLCNGIHFLLHPKVLYEISVFGIQEPESEVNTAAKAILLYLLQGRLMMTALTWNKFIESLCPVIPILQGYADTEDPLGNCILLLSKASSDTEEMLPCTTRLKSMLRLLLVKKPSVRSLALKLLAFHLTSEEGADTKRPLIDARVLSRVTDLFIGKKPIELRLDDRRELVIKLETVEKVYEIFTSDDVDLVLRKSAAEQLAVIMQDIKMHAVVKKLCLIDKIIEYLNECVSQDGKVVECLVQPCLTLLRKVLCGDPVMRVSLSQQSSLLTVLFRVSLIFHEDCSVVTEVGALFCLLLFDEVSRMDMWSVNPSNKPSLPSVFSLPVSVFRRYHLPVHVIGHHAVSPYSIVLPLSADCLALKPVSDMLRIAWNLSWYHGSDNLLKQMNSETKTQEILDALKLSTEDILTLKITHMASGLQDCLHSIVQAATHREVRAAVTRMSFYLLNDRLSLKGCPGPCGVTLKSLAWHTALNRFLQVLPACTEDEKLLIDIIHFLNKLIKEQRKNSSLELLNWILELLLRHSANPLLDLLVLTESQAREETDDIRTAVRQQLQKELIALFDTLLLNFMEVTDRKCSELLYVFQTQLALKLLQCLKVTDAPHFYGLPSLERTLRGMANLTAFPGWSSHSPLTKPLDICVKYLSGLLEVITSFYVERGGNAMSFMGKGVTKSTILCLLHLSHEMMAQAGSLEWMSLWFLPLGSHSEEHIPTQQGLAWLIPLWVDRDPEVRFTSLGLGSALTTLETGCVALANSCQNISGGLWGTVVNILLDQSECSMVRREAAFILQNLLVIPMPTEIIKDYTWQGPCVHDEDSGLSLIGKPALQALLYHCHFYEHLNQMVKHCYLGRCMFDLNFSAFDRNSESNDLNGLDDSFKFWRAPSRTSQDRDPSSLSTSETTVAPSLGSTEFQPLVQSTTLLPEASHDQFVAQGHQESTSPRPPHDSSLSAPLPKLCVFVTPSLLSAMCSLLDNLLTIAPRDTAKAFRQAHLIELLCSIADATLIQTCVQELRALLPSSPPAEHTQAQVSFLLEYLSSLSRLLQSCLLVEPDLVIQDELVKPLITNIIGILTICTKDVLDKELISAFYHTWTHLFNLLAMLLRKAGAITLPFVTVALAKHWTAAIDMFCTCAGLSATCPALYTASLQFLSVLLTEEAKGHLQAKSKTHLCCSPTVASLLDDSQENQKSLEQLSDVILQCYEGKSSKDILKRVAANALMSLLAVSRRAQKHALKANLIDNCMEQMKHINAQLNLDSLRPGKAALKKKEDGVIKELSIAMQLLRNCLYQNEECKEAALEAHLVPVLHSLWPWILMDDSLMQISLQLLCVYTANFPNGCSSLCWSSCGQHPVQATHRGAVSNSLMLCILKLASQMPLENTTVQQMVFMLLSNLALSHDCKGVIQKSNFLQNFLSLALPKGGNKHLSNLTILWLKLLLNISSGEDGQQMILRLDGCLDLLTEMSKYKHKSSPLLPLLIFHNVCFSPANKPKILANEKVITVLAACLESENQNAQRIGAAALWALIYNYQKAKTALKSPSVKRRVDEAYSLAKKTFPNSEANPLNAYYLKCLENLVQLLNSS", "length": 2226 }, "evidence": [ { "id": "E1BG09", "url": "https://omabrowser.org/oma/group/E1BG09/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R4Y8-1", "protein_name": "Rotatin", "gene_name": "Rttn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLAGLIRKLGHQLAEIRERALKSILCKIEHNLICYADLIQERLLFLHLLEWFNFPSVPMKEEVLNLLSRLVKYSPAVQHLIDLGAVEFLSKLRPNVEPVIQAEIDGILDGLFILPSEVPALCSSSYHTDQIELSQQPEVLTGYFPQDKSNFQQMEVPPGPAGNQAVKWLRFSVFPWLPLTTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDFPAEIFLQRPKIVQGLLCLVKLAFGGDGKHRLALQSVSCLQQLCTSLRNRLNFYRDPNFFSSRQDTVSQNSSLSYCHEARGPYHSPNPSPGSSSSRPSVVGRTGQRPRGDGQDWDAVSSSGSSSHTHVNSRISVHSPLDVAPVDLPELEAEDTLELQFQQLSLPQFCISTLEAAAPLLRTGSREMIIRVLELLAEDMLLIGQAISSEIWDDNSLFAINVKEKLLQVLGSLGETMCYRKTSFSMEQAEAVLVHHRMAFVSISLFTVRLLQLLLPVEKASEFLPESMSAALFFVSLDMPISLEYPEIHDTVVAYLEQLDSENYSIYKRTAEAVYSIECTCNFLSDVGKEGEKNLLELVELADQALRSFSYHQHSPLIKEIICICSKIWKSAQASPLLQGESQKVFLHMLSHPLPQVKVETYQCCLEIVKECLGVQNVTKPVSSLCSGIHFLLHPKVLYEISAFGIQESKNEVNAAAKAILLYLLQGRLMMTALTWNKFIESLAPVIPVLQGYADTEDPLGNCILLLSKVSSEAGEGALPCTARLKSVLRLLLVKKPSVRSLALKLLAFHLTSEEGADKKRPFIDAGVLSRVTNLFIVKKPIDLKLDDRRELVIKLETVKKVCDIFTSDDVDLVLRKSAAEQLAVIMQDIKMHTVVKKLCLVEKIIGHLNEFVGQDGEVIECLIQPCLTLLRKVLYADPVIRVSLSQQASLLTLLLRVSLIFHEDCTVVAEVGALFCLLLFDEVSRMDTWSDTLSDKPSLSSVFSLPVSVFRRYHLPVHVTGHHAVSPYSIVLPLPTECLTLKPVSDMLRIAWNLAWYHGSDNLLKQMTSEAKIQEFLDTLQLSTEDILALKITYTDSGLKDCLQSIIQAGGHRDVRAAITRMSFYLLNDKLSLKDDIGPCGVTLKSLAWHTVLNRFLQVLPACTEDEKLLIDIIHFLNKLIKEQRKNPSIELLNWILELLLRHNPSPLLDLLVLTDSHAGEETDDVRTAVRQQLQKELISLLNSLLLVFMTVSDRKCLELFYVFQTQLSLKLLQCLRVTDAPHFYGLPSLERTLAGMAHLTAFPGWSAHSPLSKPLEICGKYLSGLLEVITSFYVERGGNAMSFMGKGVTKSTGLCLLHLSHEMIVQAPGSEWMPLWFLPLGSHSEEHAPTQQGLAWLIPLWVDRDPEVRFTSLGLGSALTTIEAGCVALANSCQNISGGLWGTVVNILLDQSECSLVRREAAFILQNLLVIPMPSEIIKDYTWQGPCVHDEDSGLSLSGKPALQALLYHCRFYEHLTHMVKHCYVGRYIFDFNFSAFTETSEYSDLNGLDDSFKFWRAPSGTSTQDHEPSSLSTSETMVAASVVSSEIQPLLPSTLLPETALDQFVTQGQREMRPVRPRDSLLSTSLNRQYVFVTPSLLSAVCSLLDNLLAVTPRDAANAFQQAHLIELLCSTVDASLIEMCIQELKTPLPLPSAVEHIQAQASFFLEYLSSLSQLLKSCLLVEPKLVTQDELLKPLITNVIRVLIVCPKDVLDVQLVLAFYRTWTHLFDLLATLLRKAGAVSLVPLTSALAKHWEAVTDTLCRCVGLSFKCPALTIASLQFLSVLLAEEEKRRVQDKDKTNEGQAPTVALLLDGTQGSLSSSERLNETILQCYEGISPKDVLKRVAANALLSLLAVSRRAQRHALRSDLIENCMEQMKHINAQLNLDLLRPGKAVLKKKEDGFIKELSITMQLLRNCLYQNEECKVAALEARLVPVLHSLWPWLLMEDSLMQIALQLLCVYTANFPAGCSSLCWSNYGQCIQTAHRGTPSSSLILCILKLASQMPAENTTIQQLVFMFLSNLALSHDCKGVIQKSNFLQHFLSLTLPKGGNQHLSTVAILWLKLLLNMSFGEDGQQMILRLDGCLDLLIEMSKYKHKSSPHMPLLIFHNICFSPANKPKILANEKVVTLLAACLESENQTAQRIGAASLWALTYNYQKAKATLKNPSIKRKVDEAYSIAKRTLSNSEENPLNSYYLKCLENLVQLLNYS", "length": 2226 }, "evidence": [ { "id": "E1BG09", "url": "https://omabrowser.org/oma/group/E1BG09/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BG09", "url": "https://www.uniprot.org/uniprotkb/E1BG09" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1BG09", "url": "https://www.uniprot.org/uniprotkb/E1BG09" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "E1BG09", "url": "https://www.uniprot.org/uniprotkb/E1BG09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "centriole-centriole cohesion", "id": "GO:0010457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010457", "evidence": [ { "database": "UniProtKB", "id": "E1BG09", "url": "https://www.uniprot.org/uniprotkb/E1BG09" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "E1BG09", "url": "https://www.uniprot.org/uniprotkb/E1BG09" } ], "pmid": "" }, { "name": "ciliary basal body organization", "id": "GO:0032053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032053", "evidence": [ { "database": "UniProtKB", "id": "E1BG09", "url": "https://www.uniprot.org/uniprotkb/E1BG09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1028, "end_pos": 1030, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1411, "end_pos": 1413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2076, "end_pos": 2078, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2087, "end_pos": 2089, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2227, "end_pos": 2229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BG09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG09" }, { "id": "PF14726", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14726" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rotatin N-terminal", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 112, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 971, 1613 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1028, "end_pos": 1030 }, { "start_pos": 1411, "end_pos": 1413 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 2076, "end_pos": 2078 }, { "start_pos": 2087, "end_pos": 2089 }, { "start_pos": 2227, "end_pos": 2229 }, { "start_pos": 288, "end_pos": 290 }, { "start_pos": 537, "end_pos": 539 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 651, "end_pos": 653 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG16-1", "uniprot_ac": "E1BG16", "uniprot_id": "E1BG16_BOVIN", "mass": { "chemical_mass": 16957.0, "monoisotopic_mass": 16957.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "lysozyme", "type": "recommended", "evidence": [ { "id": "E1BG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG16/entry#names_and_taxonomy" } ] 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376805", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376805" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BG17", "url": "https://www.uniprot.org/uniprotkb/E1BG17#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG17", "url": "https://www.uniprot.org/uniprotkb/E1BG17" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2G27", "url": "https://www.uniprot.org/uniprotkb/E1BG17", "locus": { "chromosome": "7", "start_pos": 40918417, "end_pos": 40917488, "strand": "-", "evidence": 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"url_external": "https://alphafold.ebi.ac.uk/entry/E1BG17" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BG17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG17" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG18-1", "uniprot_ac": "E1BG18", "uniprot_id": "E1BG18_BOVIN", "mass": { "chemical_mass": 166364.0, "monoisotopic_mass": 166364.0 }, "refseq": { "ac": "XP_002698453", "name": "zinc finger protein 518A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698453" }, "gene_names": [ { "name": "ZNF518A", "type": "recommended", "evidence": [ { "id": "E1BG18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG18" } ] }, { "name": "ZNF518A", "type": "synonym", "evidence": [ { "id": "XP_002698453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698453" } ] } ], "protein_names": [ { "name": "Zinc finger protein 518A", "type": "recommended", "evidence": [ { "id": "E1BG18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG18/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 518A", "type": "synonym", "evidence": [ { "id": "XP_002698453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698453" } ] } ], "function": [ { "annotation": "Through its association with the EHMT1-EHMT2/G9A and PRC2/EED-EZH2 histone methyltransferase complexes may function in gene silencing, regulating repressive post-translational methylation of histone tails at promoters of target genes.", "evidence": [ { "database": "UniProtKB", "id": "E1BG18", "url": "https://www.uniprot.org/uniprotkb/E1BG18#function" }, { "database": "UniProtKB", "id": "ARBA00054986", "url": "https://www.uniprot.org/uniprotkb/ARBA00054986#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG18", "url": "https://www.uniprot.org/uniprotkb/E1BG18" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF518A", "url": "https://www.uniprot.org/uniprotkb/E1BG18", "locus": { "chromosome": "26", "start_pos": 17510867, "end_pos": 17455674, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021357", "url": "https://www.ensembl.org/id/ENSBTAG00000021357" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021357", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021357", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "524691", "url": "https://www.ncbi.nlm.nih.gov/gene/524691", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524691", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524691", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SCVEECM", "url": "https://omabrowser.org/oma/group/SCVEECM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BG18", "url": "https://www.orthodb.org/?gene=E1BG18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_002698453", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698453", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BG18", "url": "https://www.uniprot.org/uniprotkb/E1BG18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG18-1", "url": "https://www.uniprot.org/uniprotkb/E1BG18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSEQKHLFFDEKQNTLKKDYDVKNEVVDSLRSKISEPKFQNQLKPNISESSFHYGLKNVKIVLPKIHIPNEVLLKHEVDKYRKLFQHKPQTARKSINVKTVSSVEECMLLHQSERVDEGIKMSAKILNFSCLKCRDSTRYSPNDLQKHFQMWHHGELPSYPCEMCSFSANDFQVFKQHRRTHRITLVKCDICNNENLYTLLDLTKHFSSTHCVNGTFQCEKCEFSTQDVGTFVQHIHRHNEILYKCGKCHYICLTKGELQKHLYIHSGTFPFTCQYCSYGATRREHLVRHVITLHKEHLYAKEKLEKDKYEKRMAKSSAGLKLILKRYKIGASRKTFWRRKKVNNASDRSIEKNTQVLKKVNRTQATSEDPGHLVQEHVNEEKHERLYCENNDKPAESELGKPTLVSTGQCNGAQEGSNSTSGFLKTAVQGPTVLMVKNNRITIPANYSAKFMGFKMVDGKQHIVIKLLPTTKPNPCVPGSQSGAARDSTAVLQPQTLDATAFLTGVPAELNDTVCMKAAPPFSSSSPVLSGKVISEKEMALLSQTSNIIPAVDDEKGVSPSPVESDLITASVNLTTKVETRDNVDLWGSHITQCHPEVLGTTVKSPDKVSCTAKPNSYNSGDMHNYCINYINSELPVESSSQGSLPFHNYSKVNNSNKRRRFSGTAMCENPQRESSSSKTVLSESVLSPVKKESSNPDSRLASISLLNSKDGTLKTQAEIEEQCVLEKGQNIDGQNLYTNENKSSESMTEKPKWDGISNVESPMMPRITSVFSLQSQQASELLPPELNQLLLDVLKAKPDVKQDSSNIPDKDVPLQCAQSFQEHGGENKIVESSKDLKVQGLFPIPSGSMGTSRPTDDLNLNCSGKEKQLLSQDVRDSKTPRSFGFGTLPKTQSDAIITQQLVKDKLRATTHSFYVHNPLNSEPRKAVFVQTPKCFLVPMHFTNKPRFHVSRRPLVNTQGIPAPLLLNKKPGMILTFNNGKLEGVSAVKTESAQACGTTTKEPCRAPFLKVEQNSNCLTPALCSSIGSCVSMKSSPENTLSFKGPYIIKTPANSSVKAVPTHIIPEHQGTKLNISDSVKPQNKIFPKPPLYTFLPDGKQAVFLKCVMPNKTELLKPKLVQNSTCLKNIQPKKPEGTPQKILLKIFNPVLNVTAASNLSVSNTGSSLQKDSVPSNQTTGQQKEPESSRDALPFLLDDMMPANEIVITSTATCPESSEEPICITDHSEARVLRCKTNCTIERNFNKKNTSKRKVSRIKNHVRSQDSETAFVSRSRNCKRKCRDSYQEPPRKKALHRKCKEKAKPESIPESFEFNRPRLSKDTVRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADSPEVVNVMKTVAKFNGRVLKVSLSKRTIDALLKPVCCNPSETTYDDFPKRHKTFKPVSSVKERFVLKLTLKKTSKNNYQIVKTTSENTLKAKFNCWFCGRVFDNQDAWAGHGQRHLMEATRDWNMLE", "length": 1482, "header": "tr|E1BG18-1|E1BG18_BOVIN Isoform 1 of Zinc finger protein 518A OS=Bos taurus OX=9913 GN=ZNF518A PE=3 SV=2 CANONICAL=E1BG18-1" }, "isoforms": [ { "isoform_ac": "E1BG18-1", "url": "https://www.uniprot.org/uniprotkb/E1BG18/entry#E1BG18-1", "sequence": { "sequence": "MPSEQKHLFFDEKQNTLKKDYDVKNEVVDSLRSKISEPKFQNQLKPNISESSFHYGLKNVKIVLPKIHIPNEVLLKHEVDKYRKLFQHKPQTARKSINVKTVSSVEECMLLHQSERVDEGIKMSAKILNFSCLKCRDSTRYSPNDLQKHFQMWHHGELPSYPCEMCSFSANDFQVFKQHRRTHRITLVKCDICNNENLYTLLDLTKHFSSTHCVNGTFQCEKCEFSTQDVGTFVQHIHRHNEILYKCGKCHYICLTKGELQKHLYIHSGTFPFTCQYCSYGATRREHLVRHVITLHKEHLYAKEKLEKDKYEKRMAKSSAGLKLILKRYKIGASRKTFWRRKKVNNASDRSIEKNTQVLKKVNRTQATSEDPGHLVQEHVNEEKHERLYCENNDKPAESELGKPTLVSTGQCNGAQEGSNSTSGFLKTAVQGPTVLMVKNNRITIPANYSAKFMGFKMVDGKQHIVIKLLPTTKPNPCVPGSQSGAARDSTAVLQPQTLDATAFLTGVPAELNDTVCMKAAPPFSSSSPVLSGKVISEKEMALLSQTSNIIPAVDDEKGVSPSPVESDLITASVNLTTKVETRDNVDLWGSHITQCHPEVLGTTVKSPDKVSCTAKPNSYNSGDMHNYCINYINSELPVESSSQGSLPFHNYSKVNNSNKRRRFSGTAMCENPQRESSSSKTVLSESVLSPVKKESSNPDSRLASISLLNSKDGTLKTQAEIEEQCVLEKGQNIDGQNLYTNENKSSESMTEKPKWDGISNVESPMMPRITSVFSLQSQQASELLPPELNQLLLDVLKAKPDVKQDSSNIPDKDVPLQCAQSFQEHGGENKIVESSKDLKVQGLFPIPSGSMGTSRPTDDLNLNCSGKEKQLLSQDVRDSKTPRSFGFGTLPKTQSDAIITQQLVKDKLRATTHSFYVHNPLNSEPRKAVFVQTPKCFLVPMHFTNKPRFHVSRRPLVNTQGIPAPLLLNKKPGMILTFNNGKLEGVSAVKTESAQACGTTTKEPCRAPFLKVEQNSNCLTPALCSSIGSCVSMKSSPENTLSFKGPYIIKTPANSSVKAVPTHIIPEHQGTKLNISDSVKPQNKIFPKPPLYTFLPDGKQAVFLKCVMPNKTELLKPKLVQNSTCLKNIQPKKPEGTPQKILLKIFNPVLNVTAASNLSVSNTGSSLQKDSVPSNQTTGQQKEPESSRDALPFLLDDMMPANEIVITSTATCPESSEEPICITDHSEARVLRCKTNCTIERNFNKKNTSKRKVSRIKNHVRSQDSETAFVSRSRNCKRKCRDSYQEPPRKKALHRKCKEKAKPESIPESFEFNRPRLSKDTVRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADSPEVVNVMKTVAKFNGRVLKVSLSKRTIDALLKPVCCNPSETTYDDFPKRHKTFKPVSSVKERFVLKLTLKKTSKNNYQIVKTTSENTLKAKFNCWFCGRVFDNQDAWAGHGQRHLMEATRDWNMLE", "length": 1482, "header": "tr|E1BG18-1|E1BG18_BOVIN Isoform 1 of Zinc finger protein 518A OS=Bos taurus OX=9913 GN=ZNF518A PE=3 SV=2 CANONICAL=E1BG18-1" }, "locus": { "chromosome": "26", "start_pos": 17507720, "end_pos": 17503275, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108643.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108643.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099448.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099448.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:524691", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524691", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RRF6-1", "protein_name": "Zinc finger protein 518A", "gene_name": "Znf518a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPFEQTQLFCDEKPTILKKLDTRNEIADTIRSVSTSKISETSFQYVLKDVNICLPKINIPNEILMKHEVEKYRLLFQSKPQTARKSISVKTVSCAEECVLLCKSERAEDETVNMSAKILNFSCSKCQDSTQYSPNDLQKHFEMWHHGELPSFPCEMCSFSASDFQIFKQHRKTHRNTFVKCDICNSERSYTLLDLTKHFTSKHCVNGNFQCEECRFFTQDVGTFVQHIHRHKEVHYKCGKCHHLCFTKGELQKHLRVHSGTLPFTCHYCSYGAIHKDQLIRHVITLHKEHLYAKEKLERDQYDKRVAKTTTTGLKLILKRYKIGPTKTFWKRKTITSGNDESIGKNAQAFNIVSKTQTKSEDQSQEQVNGEKGEKQHCENGDKPVESESEKATVLSTGQYNKADEGASTTSSSVLSAVQGPTVLLVRNNKITIPANYSAKFMGFKMVDGRQHIVIKLLPANKQILPSPVLQSNTEKNSTANLSPQAVANTGFATGLTTKVNDTDFVKAAPPACSSPVLARKVISEKEAAFISEKNNTLQMVDDSKSLSSLPTTSTTSVRVTTKVEARDNVDLWENDSPQSHPDASDTSISSPDKVSLTPKPNAYSSGDMHNYCINYVNSELPAESSNSFEFSNQGSLPFHNYSKVNNKRRRFSRATLCENLQKESPNKTVTQQSTSDSDTASPLLRKESSNSDNLFASINPLNGTLKIKTEIEEPYNLEETQNFNEQSLFTNENQNLLNVTEEPKWNDIPSAGSPMMPRITSVFSLQSEQASEFLTPEVNQLLQDTLKPKSDIKEDSNNIPSKNLPFDCDQTLKKSEEVVIKSSKDFQMQDDIPVPSASVGVNVPANDLNSKCNGQEKQGLSVLQDVRDSEVTTKIPNIITLLKTQSDAIITQQLVKDKLRTTTQNSGPVYVQNPFLTSEQKNPVFVQTPKGFIIPLHVANKPGLHVFSGRPVPLVNTRSVPATLLVNKKPGMLLATNNGKPESVPTVKTENVHSYGTVTKEPCKTPFLKAEHNNSCLTPGLCSSIGNCVNMKTCSENTLPLKGSYIIKTSVNSSVKAVPNILPEQQGPKMNILDTVKQQNENLPKASLYTLMPDGKQAVFFKCVMPNNTKLLKPKLVQSSTYQHIQPKRPAGAPQKILVKIFNPVLSMSAFNNLSASNSASSFQKEIVPSKPTVHGEQKEPETSRNALPVLVHGLMPANETVHSSTTACPGSSEEPVYISERSETRVLRGKANCAVERNFNKRKTCKNKFAKIKTRIDQDSETAFVSRNRSCKRKYIDNYQEPPRKKSTLNRKGKERASAEDVQEAFGFSRPRLPKDSSRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADTPEVERVMKTIAKFNGHVLKVSLSQTTINALLKPVSNTSETTYNDFSKRQKMLKPVNSVKERFVLKLTLKKTSKNNYQIVKTTSEDVLKSQFNCWFCGRVFDNQDVWAGHGQRHLVEATRDWNMLE", "length": 1478 }, "evidence": [ { "id": "E1BG18", "url": "https://omabrowser.org/oma/group/E1BG18/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BXZ2-1", "protein_name": "Zinc finger protein 518A", "gene_name": "ZNF518A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSEQDQFSHDKKQINLLKHDAANNLCMDTSLENALVNDPLNMTTRPAVLNVNFSCELKNVKIDLPKVNIPNEVLMKHEIDKFRKLFQCKQQTARKSLTLEKVNVSSPDCSEGSQVQNKIEVQFGKGLKTTAKILHFTCTKCEDNVRYSPNDLQKHFQLLHSGELPVYPCEMCNFSANDFQAFNQHRRTHRSTLVKCELCLDEQMYTLLDLTKHFTSKHCVNGHFQCEKCGFSTQDVGTFVQHIHRHNGITYECGKCHHISYTEEEFQRHNLVHSSLILFRCQFCSYSTPRKDYILRHLIALHRDHLCAKEKLERDKFEKRILKTPAALKLVLRRYKTGTSKKPLWRRKKIIGASDKTGEKNSQVLRIVNKIQPKLDELNQYMKVVEANEEKDQIPCTEKNFTGGIHAATTAQYNKADDGMRFSLGSLKNTVHGPAVLMIKNNKISVPANYSAKFMGFKIVDGKQHIVIKLLPTNKQNLHLLGQKADPIKDGSTPPLLQTADPCSLSSGAIPHVTDQSTFKNKSIHPLTSVFSSAPHSGKAKVEKQNNSLLYGRSVSQTVAPSNVAVGKNSYNLPMKLGSPVSPHDEVTKIGTQNNISWRNYSPPSHPQVLSPPVTNTLCYDPWKIPFFPELKIQNGGLNNNHRTNNLYYSPSVDSSNEGLLSFHNYSKTDTLDNQCGVWMSTDDKSKEFISSQTVNFQNSDESASSYSESVKDLKPENTVSAQSNIKTYEHINTKNNGMSPSSQSKCGIDREYFVEDQHNGQQYLDTNLYQDLMSTAEEFQENGSDCVNSVLMPKITSVFSLQSEQAANYLSPEINQLLQDVLKVNATPQQESHCKLNNCVELHSDKLLSSQEKGNRAFTRSKNSATTCSFQRPSTNVDFHLCKRELNTRCSMHEGMHCGEERKTPRTYLDSQGMEMVCRTADGASLKDDTDAIITQQLVKDKMQSTSSNPTSFSPILQEQKKTLLVQPPPSRFFVPLQLANQPGLQVVSGKPHLSPSSSDGHATKGVPTSFALNKGPGMILTFSGSIGAVANVPSDSPQVLGRVASREYGKITIPASKVEGKNDSFRSVRSCCSRRTCSAANDSLNSMSSKGPLVVTNLAESSVKGISSVKASSEHQDAVFGSEESTEQKEMKQKQHVYAFLPDGQQAVFLKYMTPNKPVVHKHSVFQDNAHYQNCQPKKTGVMQQKLLLKIKTSDMLAETNQSVNNSVPSVQLDSVQSLTPALAQKQTDLTSNDALILPGRLMPANASLASSNPACCIPSVEPVYCTRTAGSWLQKGFVESTQIITANRNNFGSQKSSWSTQNRIAKVKPRLKQSGPKSSETVLLQRNKNFKRKNKDNCKEPPRKKVTLHRKCKEKNRGEVISESGGHYKQRASKDTVRTLKLLPFNSKQLVKCPRRNQPVVVLNHPDADVPEVVNVMKTIAKFKGHVLKVSLSKRTIEALEPAFCNHLDITTDNLFQKRHRTIKPISPVKERFVLKLTLKKTSKNNYQIVKTTSDNTLKAKFSCWFCGRIFDNQDNWVGHGQRHLMEATRDWNLLV", "length": 1540 }, "evidence": [ { "id": "E1BG18", "url": "https://omabrowser.org/oma/group/E1BG18/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SC29-1", "protein_name": "Zinc finger protein 518A", "gene_name": "ZNF518A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPSEQKHLFFDEKQNTLKKDYDVKNEIVDTVRSVLKPKISESHFHYELKNVKIVLPRINIPNEVLLKHEVDKYRKLFQHKPQTARKSISIKTVNCIEECVLLHKSERVEEGIKMSAKILNFNCLKCRDSTRYSPNDLQKHFQMWHHGELPSYPCEMCSFSANDFQVFKQHRRTHRITLVKCDICNNENLYTLLDLTKHFSSTHCVNGNFQCEKCEFSTQDVGTFVQHIHRHNEVLYKCDKCHYICLTKGELQKHLHIHSGTFPFTCQYCSYGATRREHLIRHVITLHKEHLYAKEKLEKDKYEKRMAKTSTGLKLILKRYKIGASRKTFWKRKKINNGSDRSIEKNTQVLKKVNKTQAKSEDQSRLVQEHINEEKDERLYCENNDKPAESESEKPTLLSTGQCNRAEEGSNSTTGFLKTALQGPTVLMVKNNRITIPANYSAKFMGFKMVDGKQHIVIKLLPTSKQNLYLPGSQSGATRHSTANLQPQTLDTTAFLTGVTTELNDTIYMKASTPFSCSSPIRSGKVTSEKEVALLSQTSNMLPTMDDEKSVSSLPTTSELITASVNLTTKVETRDNVDLWGSHIAQCHPEVSGTAIKSPDKVTCTVKPNPYSSGDMHNYCINYVNSELPVESSNQGSLPFHNYSKVNNSNKRRRFSGTATCENPQKESSLSKTVVQQPISESVLSLVRKESSNPDSLLASISLLNTKDGTLKTQAEMEEQCVLEKGQNIDGQNLYTNENQNLESLTEKPKWDDISSDESPMMPRITSVFSLQSQQASEFLPPEVNQLLQEVLKAKPDVKQDSSNTPSKDLRLHCDQSFQKHEREDKIVECSKDLKGQGLFPVPSCSMGINGPTNDPNLKCGGKEKQMLSMSQDVRDSEKTPRISGFGTLLKTQSDAIITQQLVKDKLRATTQNLGSLYMQSPLLNSEPKKALFVQTPRGFFVPLHIANKPGLHASGKPLPLVNTQGVPASLLLNKKPGMILTFNNGKLEGVSAVKTESAQACGTTTKEPCRPPILKVEPSSNCLTPALCSSIGSCLSMKSSSENTLSLKGPYIIKTPASSSVKAVPTPNTVSEHQGTKLNISDSVKQQNKIFPKPPLYTLLPDGKQAVFLKCVMPNKTELLKPKLVQNSTYYKNIQPKKPEGTPQKILLKIFNPVLNVTAANNLSVSNSASSASSSQKDNVPSHPATGGEQKEPESSRDALPFLLDDMMPANEIVITSTATCPESSEEPVCITDHSEARVLRRKTNCTIERCVNKKKTLKKNFSRIKTHLRSKDSETAFVSRNRNCKRKCRDSYQEPPRKKALHRKCKEKAKPEDISESFGYSKPRLSKDSVRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADAPEVVNVMKTIAKFNGRVLKVSLSKRTINALLKPVCCNSSKTICDDFPKRHKTFKPVSSVKERFVLKLTLKKTSKNNYQIVKTTSENVLKAKFNCWFCGRVFDNQDTWAGHGQRHLMEATRDWNMLE", "length": 1491 }, "evidence": [ { "id": "E1BG18", "url": "https://omabrowser.org/oma/group/E1BG18/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q499R0-1", "protein_name": "Zinc finger protein 518A", "gene_name": "Znf518a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPFEQTQLFCDEKQTILKKIDTRNEIPDTIKSIPIPKISEAGFHYEPKNVNICLPKINIPNEILMKHEVEKYRKLFQSKPQTARKSVSVRTVSCAKGCAQRCESERAEDEAGKMCAKILNFTCSKCQDRTQYSPNDLQKHFEMWHHGELPSFPCEMCSFSASDFQIFKQHRKTHRNTFVKCDICNSERSYTLLDLTKHFTSKHCVNGNFQCEECRFFTQDVGTFVQHIHRHKEVHYKCGKCHHLCFTKGELQKHLRVHSGTLPFTCHYCSYGAIHKDQLVRHVITLHKEHLYAKEKLERDQYDKRVAKTTTGLKLILKRYKIGPTKTFWKRKTIASGNDESIGKNAQAFNIVSKTQTKSEDQSQEQLNEEKGGRQHCEDGDKPIESGSEKATVLSTGQCNKADEGASAPSSVLSAVQGPTVLLVRNNKITIPANYSAKFMGFKMVDGRQHIVIKLLPANKQILPSPALQPNTEKESTANLPPQAMDNTGFATGLTAMNDTDFVKAAPLSCSSPELPRKVISEKETAFISEKNNMLQMVDDSKSVTSLPTPSESVTSVRLTTKVEARDNVDLWENPSTQSHPDLIGTSINSPDKVNLTIRPNAYSCGDMHNYCINYVNSELPAESSNCFEFSNQGSLPFHNYSKVNNKRRRFSRGAVCENLQRESSNKTVTQQSTSDSDTTSPLRKESSNSDSLLASISPLSGTLKIKTEIEEPCDLEETQNFNEQSLFTNENQNLLNMTEEPKWDDIPCAGSPMMPRITSVFSLQSEQASEFLPPEVNQLLQDTLKPRSDIKEDSNNIPSKNLPLDCDQTLKKSKEEVIKSSKDFQMQDIISVPSASVGVNVPANDLNLKCNGQEKQALSVLQDVRDPGVTTKIPSIITLLKTQSDAIITQQLVKDKLRTTTQHSGPVYVQNPLLTSEQKNPVFVQTPKGFIIPLHVANKPGLHVFSGRPVPLVNTQSVPAALLVNKKPGVVLTVNNGKPEGVPTVKTENVHSYGTVTKEPCRTPFLKAEHNRYCLTPGLCSSIGSCVNMKTCSENTLPLKGSYIIKTSVSSSVKAVPFANVLPEQQGPNVNVLDAVKQQNESLPKASLYTLMPDGKQAVFFKCMMPNNTKLLKPRLVQNSTYQRIQPKRPAGAPQKILLKIFNPVLSMSAVNNLSVGNSASSFQKEIVPSKPTVHGEQKVPQSSRDALPVSVQDLMPANEAVLSSTAACPGSSEEPVHISERSETRVSRSKANCTIERNFNKRKTCKNKFAKIKTRISQDSETAFVSRNRSCKRKYIDNYQEPPRKKSATHRKCKERANAEDVQETFGFSRPRLPKDSGRTLRLFPFNSEQLVKCPRRNQPVVVLNHPDADAPEVERVMKTITKFNGRVLKVSLSKATINALLKPVSITSETTYSDFSKRHKMLKPVNSVKERFVLKLTLKKTSKNNYQIVKTTSEDVLKSKFNCWFCGRVFDNQDVWAGHGQRHLVEATKDWNMLE", "length": 1478 }, "evidence": [ { "id": "E1BG18", "url": "https://omabrowser.org/oma/group/E1BG18/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AHZ1-1", "protein_name": "Zinc finger protein 518A", "gene_name": "ZNF518A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSEQKQLFCDEKQTTLKKDYDVKNEIVDRSAPKPKISGSIHYALKNVKIDLPKINIPNEVLLKHEVDKYRKLFQSKQQTARKSISIKTVSCVEECTLLHKSERAEEEGVKMSAKILNFSCLKCRDNTRYSPNDLQKHFQMWHHGELPSYPCEMCNFSANDFQVFKQHRRTHRSTLVKCDICNNESVYTLLNLTKHFTSTHCVNGNFQCEKCKFSTQDVGTFVQHIHRHNEIHYKCGKCHHVCFTKGELQKHLHIHSGTFPFTCQYCSYGATRREHLVRHVITLHKEHLYAKEKLEKDKYEKRMAKTSAGLKLILKRYKIGASRKTFWKRKKINSGSDRSIEKNTQVLKKMNKTQTKSEDQSHVVQEHLSEEKDERLHCENNDKAPESESEKPTPLSTGQGNRAEEGPNASSGFMKTAVLGPTLKNVMMKNNKLAVSPNYNATFMGFKMMDGKQHIVLKLVPIKQNVCSPGSQSGAAKDGTANLQPQTLDTNGFLTGVTTELNDTVYMKAATPFSCSSSILSGKASSEKEMTLISQRNNMLQTMDYEKSVSSLSATSELVTASVNLTTKFETRDNVDFWGNHLTQSHPEVLGTTIKSPDKVNCVAKPNAYNSGDMHNYCINYGNCELPVESSNQGSLPFHNYSKVNNSNKRRRFSGTAVYENPQRESSSSKTVVQQPISESFLSLVRQESSKPDSLLASISLLNDKDGTLKAKSEIEEQYVLEKGQNIDGQNLYSNENQNLECATEKSKWEDFSNVDSPMMPRITSVFSLQSQQASEFLPPEVNQLLQDVLKIKPDVKQDSSNTPNKGLPLHCDQSFQKHEREGKIVESSKDFKVQGIFPVPPGSVGINVPTNDLNLKFGKEKQVSSIPQDVRDSEKMPRISGFGTLLKTQSDAIITQQLVKDKLRATTQNLGSFYMQSPLLNSEQKKTIIVQTSKGFLIPLNITNKPGLPVIPGNALPLVNSQGIPASLFVNKKPGMVLTLNNGKLEGVSAVKTEGAPARGTVTKEPCKTPILKVEPNNNCLTPGLCSSIGSCLSMKSSSENTLPLKGPYILKPTSSVKAVLIPNMLSEQQSTKLNISDSVKQQNEIFPKPPLYTFLPDGKQAVFLKCVMPNKTELLKPKLVQNSTYQNIQPKKPEGTPQRILLKIFNPVLNVTAANNLSVSNSASSLQKDNVPSNQIIGGEQKEPESRDALPFLLDDLMPANEIVITSTATCPESSEEPICVSDCSESRVLRCKTNCRIERNFNRKKTSKKIFSKTKTHGSKDSETAFVSRNRNCKRKCRDSYQEPPRRKATLHRKCKEKAKPEDVRETFGFSRPRLSKDSIRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADAPEVVSVMKTIAKFNGHVLKVSLSKRTINALLKPVCYNPPKTTYDDFSKRHKTFKPVSSVKERFVLKLTLKKTSKNNYQIVKTTSENILKAKFNCWFCGRVFDNQDTWAGHGQRHLMEATRDWNMLE", "length": 1483 }, "evidence": [ { "id": "E1BG18", "url": "https://omabrowser.org/oma/group/E1BG18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BG18", "url": "https://www.uniprot.org/uniprotkb/E1BG18" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BG18", "url": "https://www.uniprot.org/uniprotkb/E1BG18" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BG18", "url": "https://www.uniprot.org/uniprotkb/E1BG18" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BG18", "url": "https://www.uniprot.org/uniprotkb/E1BG18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BG18", "url": "https://www.uniprot.org/uniprotkb/E1BG18" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BG18", "url": "https://www.uniprot.org/uniprotkb/E1BG18" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "E1BG18", "url": "https://www.uniprot.org/uniprotkb/E1BG18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1055, "end_pos": 1057, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1075, "end_pos": 1077, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1111, "end_pos": 1113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1123, "end_pos": 1125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1152, "end_pos": 1154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1158, "end_pos": 1160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1176, "end_pos": 1178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1237, "end_pos": 1239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1248, "end_pos": 1250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" }, { "start_pos": 864, "end_pos": 866, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BG18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG18" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 272, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1055, "end_pos": 1057 }, { "start_pos": 1075, "end_pos": 1077 }, { "start_pos": 1111, "end_pos": 1113 }, { "start_pos": 1123, "end_pos": 1125 }, { "start_pos": 1152, "end_pos": 1154 }, { "start_pos": 1158, "end_pos": 1160 }, { "start_pos": 1176, "end_pos": 1178 }, { "start_pos": 1237, "end_pos": 1239 }, { "start_pos": 1248, "end_pos": 1250 }, { "start_pos": 129, "end_pos": 131 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 47, "end_pos": 49 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 575, "end_pos": 577 }, { "start_pos": 651, "end_pos": 653 }, { "start_pos": 656, "end_pos": 658 }, { "start_pos": 744, "end_pos": 746 }, { "start_pos": 864, "end_pos": 866 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG19-1", "uniprot_ac": "E1BG19", "uniprot_id": "E1BG19_BOVIN", "mass": { "chemical_mass": 40213.0, "monoisotopic_mass": 40213.0 }, "refseq": {}, "gene_names": [ { "name": "SULT2A1", "type": "recommended", "evidence": [ { "id": "E1BG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG19" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "E1BG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG19/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "E1BG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG19/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG19", "url": "https://www.uniprot.org/uniprotkb/E1BG19" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SULT2A1", "url": "https://www.uniprot.org/uniprotkb/E1BG19", "locus": {} } ], "crossref": [ { "id": "E1BG19", "url": "https://alphafold.ebi.ac.uk/entry/E1BG19", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000023419", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000023419", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000039971", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039971", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BG19", "url": "https://www.orthodb.org/?gene=E1BG19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11783", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11783", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-156584", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156584", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9753281", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9753281", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "70607", "url": "https://www.rhea-db.org/rhea/70607", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BG19", "url": "https://www.uniprot.org/uniprotkb/E1BG19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG19-1", "url": "https://www.uniprot.org/uniprotkb/E1BG19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0S6", "url": "https://www.uniprot.org/uniprotkb/F1N0S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0S6-1", "url": "https://www.uniprot.org/uniprotkb/F1N0S6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGKFLWFEGIPFPSVDYSPELLREVQESFLIKDEDVLLLTFPKSGVILKEEQREKRREEEKKNDTGRPSFGVILKEEQREKRRQKEKKNDTRRPSFGTNWLIETVCLIYSKGDPKWVQSEPIWDRSPWVETKHGYELLKEKEGPRLISSHLPIQLFPKSFFKSKAKVIYLVRNPRDVFVSGYFFWKSAKFVKRPQSLEQYFEWFIQGNMPFGSWFDHIRGWMSMRDKENFLVLSYEEMKWDTRSTVEKICQFLGKKLEPEELNSVLKNNSFQVMKENNMSNFSLLKGQYLEENGLLLRKGVTGDWKNYFTVAQAEIFDKLFQEKMADLPQELFAWE", "length": 337, "header": "tr|E1BG19-1|E1BG19_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=SULT2A1 PE=3 SV=3 CANONICAL=E1BG19-1" }, "isoforms": [ { "isoform_ac": "E1BG19-1", "url": "https://www.uniprot.org/uniprotkb/E1BG19/entry#E1BG19-1", "sequence": { "sequence": "MTGKFLWFEGIPFPSVDYSPELLREVQESFLIKDEDVLLLTFPKSGVILKEEQREKRREEEKKNDTGRPSFGVILKEEQREKRRQKEKKNDTRRPSFGTNWLIETVCLIYSKGDPKWVQSEPIWDRSPWVETKHGYELLKEKEGPRLISSHLPIQLFPKSFFKSKAKVIYLVRNPRDVFVSGYFFWKSAKFVKRPQSLEQYFEWFIQGNMPFGSWFDHIRGWMSMRDKENFLVLSYEEMKWDTRSTVEKICQFLGKKLEPEELNSVLKNNSFQVMKENNMSNFSLLKGQYLEENGLLLRKGVTGDWKNYFTVAQAEIFDKLFQEKMADLPQELFAWE", "length": 337, "header": "tr|E1BG19-1|E1BG19_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=SULT2A1 PE=3 SV=3 CANONICAL=E1BG19-1" }, "locus": { "chromosome": "18", "start_pos": 54750137, "end_pos": 54732152, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031917.5", "url": "https://www.ensembl.org/id/ENSBTAT00000031917.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000031863.5", "url": "https://www.ensembl.org/id/ENSBTAP00000031863.5" } ] } }, { "isoform_ac": "F1N0S6-1", "url": "https://www.uniprot.org/uniprotkb/E1BG19/entry#F1N0S6-1", "sequence": { "sequence": "MTGKFLWFEGIPFPSVDYSPELLREVQESFLIKDEDVLLLTFPKSGVILKEEQREKRRQKEKKNDTRRPSFGTNWLIETVCLIYSKGDPKWVQSEPIWDRSPWVETKHGYELLKEKEGPRLISSHLPIQLFPKSFFKSKAKVIYLVRNPRDVFVSGYFFWKSAKFVKRPQSLEQYFEWFIQGNMPFGSWFDHIRGWMSMRDKENFLVLSYEEMKWDTRSTVEKICQFLGKKLEPEELNSVLKNNSFQVMKENNMSNFSLLKGQYLEENGLLLRKGVTGDWKNYFTVAQAEIFDKLFQEKMADLPQELFAWE", "length": 311, "header": "tr|F1N0S6-1|E1BG19_BOVIN Computationally mapped isoform of Sulfotransferase OS=Bos taurus OX=9913 GN=SULT2A1 PE=3 SV=3 CANONICAL=E1BG19-1" }, "locus": { "chromosome": "18", "start_pos": 54750137, "end_pos": 54732152, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028234.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028234.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028234.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028234.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-156584", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156584", "resource": "Reactome", "description": "Cytosolic sulfonation of small molecules" }, { "id": "R-BTA-9753281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9753281", "resource": "Reactome", "description": "Paracetamol ADME" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "E1BG19", "url": "https://www.uniprot.org/uniprotkb/E1BG19" } ], "pmid": "" }, { "name": "aryl sulfotransferase activity", "id": "GO:0004062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004062", "evidence": [ { "database": "UniProtKB", "id": "E1BG19", "url": "https://www.uniprot.org/uniprotkb/E1BG19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sulfation", "id": "GO:0051923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051923", "evidence": [ { "database": "UniProtKB", "id": "E1BG19", "url": "https://www.uniprot.org/uniprotkb/E1BG19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BG19", "url": "https://www.uniprot.org/uniprotkb/E1BG19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70607", "name": "", "equation": "4-ethylphenol + 3'-phosphoadenylyl sulfate = 4-ethylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3T0Y3-1", "P50227-1", "P19217-1", "A0AAA9RW31-1", "A0A3Q1N4J6-1", "F1MZX9-1", "E1BG19-1", "E1BAC7-1", "E1BIS9-1", "A0ABI0NTS0-1", "A0AAA9SGU9-1", "A0ABI0P531-1", "E1BJ78-1" ], "evidence": [ { "id": "70607", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70607" } ] }, { "id": "R-BTA-176474", "name": "3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176486" ], "output_participant_list": [ "R-ALL-176519" ], "enzyme_list": [ "Q3T0Y3-1", "P50227-1", "F1MZX9-1", "E1BG19-1", "A0ABI0NTS0-1" ], "evidence": [ { "id": "R-BTA-176474", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176474" } ] }, { "id": "R-BTA-176585", "name": "3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176667" ], "output_participant_list": [ "R-ALL-176564" ], "enzyme_list": [ "Q3T0Y3-1", "P50227-1", "F1MZX9-1", "E1BG19-1", "A0ABI0NTS0-1" ], "evidence": [ { "id": "R-BTA-176585", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176585" } ] }, { "id": "R-BTA-176588", "name": "lithocholate + PAPS => lithocholate sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176655" ], "output_participant_list": [ "R-ALL-176555" ], "enzyme_list": [ "E1BG19-1" ], "evidence": [ { "id": "R-BTA-176588", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176588" } ] }, { "id": "R-BTA-176604", "name": "taurolithocholate + PAPS => taurolithocholate sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176565" ], "output_participant_list": [ "R-ALL-176483" ], "enzyme_list": [ "E1BG19-1" ], "evidence": [ { "id": "R-BTA-176604", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176604" } ] }, { "id": "R-BTA-176631", "name": "dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176626" ], "output_participant_list": [ "R-ALL-176496" ], "enzyme_list": [ "E1BG19-1" ], "evidence": [ { "id": "R-BTA-176631", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176631" } ] }, { "id": "R-BTA-176664", "name": "estrone + PAPS => estrone 3-sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176575" ], "output_participant_list": [ "R-ALL-176501" ], "enzyme_list": [ "E1BG19-1" ], "evidence": [ { "id": "R-BTA-176664", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176664" } ] }, { "id": "R-BTA-9753277", "name": "SULT dimers sulfate APAP to APAP-SO3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-9753448" ], "enzyme_list": [ "P50227-1", "A0AAA9RW31-1", "E1BG19-1" ], "evidence": [ { "id": "R-BTA-9753277", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9753277" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-176483", "participant_name": "taurolithocholate sulfate [cytosol]", "crossref": [ { "id": "8143976", "database": "PubChem Substance", "url": "" }, { "id": "HMDB0002580", "database": "HMDB Metabolite", "url": "" }, { "id": "ZINC000004096163", "database": "ZINC", "url": "" }, { "id": "17864", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-176486", "participant_name": "3,3'-diiodothyronine [cytosol]", "crossref": [ { "id": "35430", "database": "ChEBI", "url": "" }, { "id": "11533682", "database": "PubChem Substance", "url": "" }, { "id": "ZINC000016051523", "database": "ZINC", "url": "" }, { "id": "ZINC000045331653", "database": "ZINC", "url": "" }, { "id": "HMDB0005869", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-176496", "participant_name": "DHEA-SO4 [cytosol]", "crossref": [ { "id": "ZINC000004096458", "database": "ZINC", "url": "" }, { "id": "57905", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-176501", "participant_name": "E1S [cytosol]", "crossref": [ { "id": "ZINC000003876186", "database": "ZINC", "url": "" }, { "id": "60050", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-176519", "participant_name": "3,3'-diiodothyronine 4-sulfate [cytosol]", "crossref": [ { "id": "35431", "database": "ChEBI", "url": "" }, { "id": "ZINC000031706818", "database": "ZINC", "url": "" }, { "id": "11533681", "database": "PubChem Substance", "url": "" } ] }, { "participant_id": "R-ALL-176555", "participant_name": "lithocholate sulfate [cytosol]", "crossref": [ { "id": "ZINC000012494532", "database": "ZINC", "url": "" }, { "id": "133940", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-176564", "participant_name": "3,5,3'-triiodothyronine 4-sulfate [cytosol]", "crossref": [ { "id": "ZINC000085552312", "database": "ZINC", "url": "" }, { "id": "35432", "database": "ChEBI", "url": "" }, { "id": "HMDB0003036", "database": "HMDB Metabolite", "url": "" }, { "id": "11533680", "database": "PubChem Substance", "url": "" } ] }, { "participant_id": "R-ALL-176565", "participant_name": "taurolithocholate [cytosol]", "crossref": [ { "id": "17179", "database": "ChEBI", "url": "" }, { "id": "8143664", "database": "PubChem Substance", "url": "" }, { "id": "C02592", "database": "COMPOUND", "url": "" }, { "id": "ZINC000004095893", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-176575", "participant_name": "E1 [cytosol]", "crossref": [ { "id": "17263", "database": "ChEBI", "url": "" }, { "id": "8144215", "database": "PubChem Substance", "url": "" }, { "id": "C00468", "database": "COMPOUND", "url": "" }, { "id": "2818", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000013509425", "database": "ZINC", "url": "" }, { "id": "HMDB0000145", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-176626", "participant_name": "DHEA [cytosol]", "crossref": [ { "id": "28689", "database": "ChEBI", "url": "" }, { "id": "8145544", "database": "PubChem Substance", "url": "" }, { "id": "C01227", "database": "COMPOUND", "url": "" }, { "id": "2370", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000003807917", "database": "ZINC", "url": "" }, { "id": "HMDB0000077", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-176655", "participant_name": "LCA [cytosol]", "crossref": [ { "id": "29744", "database": "ChEBI", "url": "" }, { "id": "ZINC000003918156", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-176667", "participant_name": "T3 [cytosol]", "crossref": [ { "id": "533015", "database": "ChEBI", "url": "" }, { "id": "ZINC000003830999", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9753448", "participant_name": "APAP-SO3 [cytosol]", "crossref": [ { "id": "8147600", "database": "PubChem Substance", "url": "" }, { "id": "HMDB0059911", "database": "HMDB Metabolite", "url": "" }, { "id": "ZINC000002382375", "database": "ZINC", "url": "" }, { "id": "32635", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1N4J6", "gene_name": "", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1N4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4J6" } ] } ] }, { "uniprot_ac": "A0AAA9RW31", "gene_name": "LOC100300896", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0AAA9RW31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW31" } ] } ] }, { "uniprot_ac": "A0AAA9SGU9", "gene_name": "LOC514658", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0AAA9SGU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGU9" } ] } ] }, { "uniprot_ac": "A0ABI0NTS0", "gene_name": "SULT1C2", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0ABI0NTS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0" } ] } ] }, { "uniprot_ac": "A0ABI0P531", "gene_name": "LOC112446736", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0ABI0P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P531" } ] } ] }, { "uniprot_ac": "E1BAC7", "gene_name": "SULT1D1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BAC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAC7" } ] } ] }, { "uniprot_ac": "E1BG19", "gene_name": "SULT2A1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG19" } ] } ] }, { "uniprot_ac": "E1BIS9", "gene_name": "SULT1C3", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ] } ] }, { "uniprot_ac": "E1BJ78", "gene_name": "LOC783020", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BJ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ78" } ] } ] }, { "uniprot_ac": "F1MZX9", "gene_name": "SULT6B1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "F1MZX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZX9" } ] } ] }, { "uniprot_ac": "P19217", "gene_name": "SULT1E1", "activity": [ { "ec_number": "2.8.2.4", "activity": "estrone + 3'-phosphoadenylyl sulfate = estrone 3-sulfate + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "P19217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19217" } ] }, { "ec_number": "2.8.2.4", "activity": "", "evidence": [ { "id": "P19217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19217" } ] } ] }, { "uniprot_ac": "P50227", "gene_name": "SULT1A1", "activity": [ { "ec_number": "2.8.2.1", "activity": "a phenol + 3'-phosphoadenylyl sulfate = an aryl sulfate + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "P50227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50227" } ] }, { "ec_number": "2.8.2.1", "activity": "", "evidence": [ { "id": "P50227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50227" } ] } ] }, { "uniprot_ac": "Q3T0Y3", "gene_name": "SULT1B1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "Q3T0Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Y3" } ] }, { "ec_number": "2.8.2.1", "activity": "a phenol + 3'-phosphoadenylyl sulfate = an aryl sulfate + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "Q3T0Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Y3" } ] }, { "ec_number": "2.8.2.1", "activity": "", "evidence": [ { "id": "Q3T0Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Y3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BG19-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 337, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BG19-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BG19" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG19" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 329, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG25-1", "uniprot_ac": "E1BG25", "uniprot_id": "E1BG25_BOVIN", "mass": { "chemical_mass": 80694.0, "monoisotopic_mass": 80694.0 }, "refseq": { "ac": "NP_001179241", "name": "melanotransferrin precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179241" }, "gene_names": [ { "name": "MELTF", "type": "recommended", "evidence": [ { "id": "E1BG25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ] }, { "name": "MELTF", "type": "synonym", "evidence": [ { "id": "NP_001179241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179241" } ] } ], "protein_names": [ { "name": "Melanotransferrin", "type": "recommended", "evidence": [ { "id": "E1BG25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG25/entry#names_and_taxonomy" } ] }, { "name": "melanotransferrin precursor", "type": "synonym", "evidence": [ { "id": "NP_001179241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179241" } ] } ], "function": [ { "annotation": "Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25#function" }, { "database": "UniProtKB", "id": "ARBA00054140", "url": "https://www.uniprot.org/uniprotkb/ARBA00054140#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MELTF", "url": "https://www.uniprot.org/uniprotkb/E1BG25", "locus": { "chromosome": "1", "start_pos": 71475841, "end_pos": 71500659, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002998", "url": "https://www.ensembl.org/id/ENSBTAG00000002998" } ] } } ], "crossref": [ { "id": "E1BG25", "url": "https://alphafold.ebi.ac.uk/entry/E1BG25", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002998", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002998", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13529", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13529", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539803", "url": "https://www.ncbi.nlm.nih.gov/gene/539803", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539803", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539803", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPVPAMT", "url": "https://omabrowser.org/oma/group/CPVPAMT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BG25", "url": "https://www.orthodb.org/?gene=E1BG25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11485", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11485", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11485:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11485:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00405", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00405", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179241", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG25-1", "url": "https://www.uniprot.org/uniprotkb/E1BG25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGSSVALWLFVTLRTVLGGMEVRWCTISDPEQQKCSDMSKAFQQAGIQPSVLCVQGTSADHCVQLITAQEADAITLDGGAIYQAGKEHGLKPVVGEVYDQEIGTSYYAVAVVKRGSQVTINTLKGMKSCHTGINRTVGWNVPVGYLVESGRLSVMGCDVLRAVSDYFGGSCVPGAGETSYSESLCRLCRGDSTGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGQALLSQDFELLCQDGTRADVTEWRQCHLARVPAHAVVVRADTDGGLIFRLLNEGQRLFSHEGSSFHMFSSEAYGQKNLLFKDATSELVPIATQTYEAWLGREYLHAMKGLLCDPNRLPHYLRWCVLSTPEIQKCGDMAVAFSRQRLKPEIQCVSAESPQQCMERIQAGQIDAVTLKGEDIYTAGKTYGLVPAAGEHYTPEDRSNSYFVVAVVKRNSSYAFTLDELRGKRSCHPGFGSPAGWDIPVGTLVQRGFIRPRDCDVLTAVSEFFSASCVPVNNPQNYPSSLCALCVGDEQGRNKCVGNSQERYYGYSGAFRCLVENAGDVAFVKHTTVFDNTNGHSSEPWAAELMSEDYELLCPNGARAEVTQFAACNLAQIPSHAVMVRPDTNIFTVYGLLDKAQDLFGDDHNKNGFKMFDSSSYHGQDLLFKDATIRVVPVGEKTTYRSWLGPDYVVALEGMLSQQCSGTVTSASRVSLLLLLLPLALTASLLQPCL", "length": 739, "header": "tr|E1BG25-1|E1BG25_BOVIN Isoform 1 of Melanotransferrin OS=Bos taurus OX=9913 GN=MELTF PE=3 SV=1 CANONICAL=E1BG25-1" }, "isoforms": [ { "isoform_ac": "E1BG25-1", "url": "https://www.uniprot.org/uniprotkb/E1BG25/entry#E1BG25-1", "sequence": { "sequence": "MRGSSVALWLFVTLRTVLGGMEVRWCTISDPEQQKCSDMSKAFQQAGIQPSVLCVQGTSADHCVQLITAQEADAITLDGGAIYQAGKEHGLKPVVGEVYDQEIGTSYYAVAVVKRGSQVTINTLKGMKSCHTGINRTVGWNVPVGYLVESGRLSVMGCDVLRAVSDYFGGSCVPGAGETSYSESLCRLCRGDSTGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGQALLSQDFELLCQDGTRADVTEWRQCHLARVPAHAVVVRADTDGGLIFRLLNEGQRLFSHEGSSFHMFSSEAYGQKNLLFKDATSELVPIATQTYEAWLGREYLHAMKGLLCDPNRLPHYLRWCVLSTPEIQKCGDMAVAFSRQRLKPEIQCVSAESPQQCMERIQAGQIDAVTLKGEDIYTAGKTYGLVPAAGEHYTPEDRSNSYFVVAVVKRNSSYAFTLDELRGKRSCHPGFGSPAGWDIPVGTLVQRGFIRPRDCDVLTAVSEFFSASCVPVNNPQNYPSSLCALCVGDEQGRNKCVGNSQERYYGYSGAFRCLVENAGDVAFVKHTTVFDNTNGHSSEPWAAELMSEDYELLCPNGARAEVTQFAACNLAQIPSHAVMVRPDTNIFTVYGLLDKAQDLFGDDHNKNGFKMFDSSSYHGQDLLFKDATIRVVPVGEKTTYRSWLGPDYVVALEGMLSQQCSGTVTSASRVSLLLLLLPLALTASLLQPCL", "length": 739, "header": "tr|E1BG25-1|E1BG25_BOVIN Isoform 1 of Melanotransferrin OS=Bos taurus OX=9913 GN=MELTF PE=3 SV=1 CANONICAL=E1BG25-1" }, "locus": { "chromosome": "1", "start_pos": 71500527, "end_pos": 71476845, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046533.4", "url": "https://www.ensembl.org/id/ENSBTAT00000046533.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043824.2", "url": "https://www.ensembl.org/id/ENSBTAP00000043824.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539803", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539803", "resource": "KEGG Pathway" }, { "id": "R-BTA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" }, { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-BTA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z1N4-1", "protein_name": "Ovotransferrin", "gene_name": "MELTF", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSCTFSWFTLGVCDVLPFCCHSQVLMVNALNFTKALSLERVRWCTMSNQELSKCKDMSNAFTGAGILPPLECMEGESAANCTQMIKDYLADAVTLDGRWIYQAGKEYGLKPVVGEVYDQEIGTSYYAVAVVRKGSNITINSLKGVRSCHTGINRTAGWNVPVGYLIDSGRLPAMGCDLPKAVSDYFSASCVPGTNSASYPTSLCQLCKGDSSGQNKCQGNSQEQYYDYSGAFRCLAEGAGEVAFVKHSTVPENTDGRTLSTWAQQLRSKDFQLLCRNGSTADVTEWRTCHLARVPARAVVVRPDTDGTAVFQLLNQGQQRFNDVGAQFQMFDSTAYGAQNLMFRDSTTKLVAVTSQNYQAWLGDEYLHAMQALSCDPNTLPESLNWCVVSTEEIWKCGEMGTAFRSKNLKPEIQCISAKTKEECMEMIQKKEIDVVALGGADIYIAGKTYGLVPAAGESFSAEDNNNAYYAVALVKRNPSNAFTINDLKGKKSCHTGLGRTAGWNIPIGMLVKKGFINPRDCNIPQAVSEFFSASCVPSAEQGNYPSTLCQLCIGDNNGNNKCSASSQERYYSYNGAFRCLAEDAGDVAFVKHSTVFENTDGKNTESWARDLKSSGFQLLCRNGARAEVTQFAQCHLARVPAQAIMVHPDTNIFALYGLLDKAQEYFGNNSNRNGFKMFDSSAFQGKDLIFKDSAVKIVPVEERRTYAEWLGSEYVESLEGMQTPQCSGAGNKLIQQHLLVITFVPFIILGQLQGLG", "length": 757 }, "evidence": [ { "id": "E1BG25", "url": "https://omabrowser.org/oma/group/E1BG25/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ADK7-1", "protein_name": "Melanotransferrin", "gene_name": "Meltf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLSVTFWLLLSLRTVLCVMEMQWCTISDPEQQKCKDMSKAFQGAGIQPSLLCVQGTSTDHCVQLIKDQKADAITLDGGAIYQAGKEYGLKPVVGEVYDQDIGTSYYAVAVVRRNSNVTINTLKGVKSCHTGINRTVGWNVPVGYLVETGHLSVMGCDVLKAVGDYFGGSCVPGAGETSHSESLCRLCRGDSSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGKALMSQDFQLLCRDGSRADITEWRRCHLAKVPAHAVVVRDDMDGGLIFRLLNEGQLLFSHEDSSFQMFSSKAYGQKNLLFKDSTLELVPIATQNYESWLGQEYLHAMKGLLCDPNRLPHYLRWCVLSVPEIQKCGDMAVAFSRQSLKPEIQCVSAESPEHCMQQIQAGHIDAVTLRGEDIYRAGKAYGLVPAAGELYAEEDRSNSYFVVAVVRRDSSYSFTLDELRSKRSCHPGLGSPAGWEVPIGSLIQRGFIRPKDCDVLTAVSEFFNASCVPVNNPKNYPSSLCALCVGDEKGRNKCVGSSQERYYGYSGAFRCLVENAGDVAFLKHTTVFENTNGHNPEPWASHLRWQDYELLCPNGARAEVDQFQACNLAQMPSHAVMVHPDTNIFTVYGLLDKAQDLFGDDHNKNGFQMFDSSKYHSQDLLFKDATVRAVPVREKTTYLDWLGPDYVVALEGMLSQQCSGAGAAVHRVPPPALLLLALAAGLLPRVL", "length": 738 }, "evidence": [ { "id": "E1BG25", "url": "https://omabrowser.org/oma/group/E1BG25/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SQX4-1", "protein_name": "Melanotransferrin", "gene_name": "MELTF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRGPNVALWLCLALRTALGGMEVRWCTISDPEQQKCSDMSKAFQEAGIQPSLLCVQGTSADHCVQLITAREADAITLDGGAIYEAGKEHSLKPVVGEVYDQEVGTSYYAVAVVKRGSRVTINTLKGMKSCHTGINRTVGWNVPVGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGDTSYSESLCRLCRGNTAGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGQALLSQDFELLCRDGSRADVTEWRRCHLARVPSHAVVVRADTDGGLIFRLLNEGQRLFSHEGSSFQMFSSDAYGQKNLLFKDATSELVPIATQTYEAWLGHEYVQAMKGLLCDPNRLPHYLRWCVLSTPEIQKCGDMAVAFSRQRLKPEIQCVSADSPQHCMERIQAGHIDAVTLRGEDIYMAGKTYGLVPAAGEHYAPEDRSNSYFVVAVVKRNSSYAFTLDELRGKRSCHPGFGSLAGWDIPVGALVQRGFIRPRDCDVLTAVSEFFSASCVPVNNPKNYPSSLCALCVGDEQGRNKCVGNSQERYYGYSGAFRCLVENAGDVAFVKHTTVFDNTNGHNSEPWAAVLMSEDYELLCPNGARAEVTQFAACNLAQIPSQAVMVRPDTNIFTVYGLLDKAQDLFGDDHNKNGFKMFDSSNYHGQDLLFKDATIRVVPVGERTTYRDWLGPDYVAALEGMLSQQCSGAAVTASGVSLLLLPLALTAGLLQPSL", "length": 737 }, "evidence": [ { "id": "E1BG25", "url": "https://omabrowser.org/oma/group/E1BG25/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P08582-1", "protein_name": "Melanotransferrin", "gene_name": "MELTF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGPSGALWLLLALRTVLGGMEVRWCATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRRSSHVTIDTLKGVKSCHTGINRTVGWNVPVGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSESLCRLCRGDSSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGQALLSQDFELLCRDGSRADVTEWRQCHLARVPAHAVVVRADTDGGLIFRLLNEGQRLFSHEGSSFQMFSSEAYGQKDLLFKDSTSELVPIATQTYEAWLGHEYLHAMKGLLCDPNRLPPYLRWCVLSTPEIQKCGDMAVAFRRQRLKPEIQCVSAKSPQHCMERIQAEQVDAVTLSGEDIYTAGKTYGLVPAAGEHYAPEDSSNSYYVVAVVRRDSSHAFTLDELRGKRSCHAGFGSPAGWDVPVGALIQRGFIRPKDCDVLTAVSEFFNASCVPVNNPKNYPSSLCALCVGDEQGRNKCVGNSQERYYGYRGAFRCLVENAGDVAFVRHTTVFDNTNGHNSEPWAAELRSEDYELLCPNGARAEVSQFAACNLAQIPPHAVMVRPDTNIFTVYGLLDKAQDLFGDDHNKNGFKMFDSSNYHGQDLLFKDATVRAVPVGEKTTYRGWLGLDYVAALEGMSSQQCSGAAAPAPGAPLLPLLLPALAARLLPPAL", "length": 738 }, "evidence": [ { "id": "E1BG25", "url": "https://omabrowser.org/oma/group/E1BG25/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R0R1-1", "protein_name": "Melanotransferrin", "gene_name": "Meltf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLLSVTFWLLLSLRTVVCVMEVQWCTISDAEQQKCKDMSEAFQGAGIRPSLLCVQGNSADHCVQLIKEQKADAITLDGGAIYEAGKEHGLKPVVGEVYDQDIGTSYYAVAVVRRNSNVTINTLKGVKSCHTGINRTVGWNVPVGYLVESGHLSVMGCDVLKAVGDYFGGSCVPGTGETSHSESLCRLCRGDSSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGNTLPSWGKSLMSEDFQLLCRDGSRADITEWRRCHLAKVPAHAVVVRGDMDGGLIFQLLNEGQLLFSHEDSSFQMFSSKAYSQKNLLFKDSTLELVPIATQNYEAWLGQEYLQAMKGLLCDPNRLPHYLRWCVLSAPEIQKCGDMAVAFSRQNLKPEIQCVSAESPEHCMEQIQAGHTDAVTLRGEDIYRAGKVYGLVPAAGELYAEEDRSNSYFVVAVARRDSSYSFTLDELRGKRSCHPYLGSPAGWEVPIGSLIQRGFIRPKDCDVLTAVSQFFNASCVPVNNPKNYPSALCALCVGDEKGRNKCVGSSQERYYGYSGAFRCLVEHAGDVAFVKHTTVFENTNGHNPEPWASHLRWQDYELLCPNGARAEVDQFQACNLAQMPSHAVMVRPDTNIFTVYGLLDKAQDLFGDDHNKNGFQMFDSSKYHSQDLLFKDATVRAVPVREKTTYLDWLGPDYVVALEGMLSQQCSGAGAAVQRVPLLALLLLTLAAGLLPRVL", "length": 738 }, "evidence": [ { "id": "E1BG25", "url": "https://omabrowser.org/oma/group/E1BG25/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTZ5-1", "protein_name": "Transferrin 2", "gene_name": "Tsf2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASSLVFVALVGALCFTLANAQHHYDEHKTTRMVWCTKSQAEQYKCQNLTVAIERDRALFDEVFLNLTCFMAYSADECIHHIDREKAHITTLDAGDVFTAGRYNSLIPIMQEKLEGGFADYQSVAVIKKGSLPDLNNLRDMRNKRVCFPWVGSLAGWIVPIHTLQREGGMEVVDCNNQVKTAASYFNNSCAVYSLSDKHNPIGDNSDKLCTLCTGKIPGGRCSSADPYFGYEGAFKCLLEKGDVAFLRHSTVNEMLQTTEFKNIAPDTFELLCRDGRRASINDYRQCNWGQVPADAIVTSSARSFSDRKQYQQFLKRIAELYSDGTRDDQSRQGGQSFNSRNNINDQNAYGQFDNNDPYRTQNQYDQYRSERLDSSFAEERNQQDGTNTSILYEKFRIFESKRYGKPNLLFQDSSRALTVIPEDDQSFTKYLGPAINFIYGIRECPVPAMTLCVTSENELDKCIKMRTALKAHLLKPELICKKMHSHINCMQFIEAGKADISVFDAGDVYTGGLNYDLVPFMSEVYNLGEPEYYVVAVAKEDDPDTELTYLKGKNTCHTGINTAAGWTYPMALFISNGWIRPYGCDSVRAAAEYFTKSCVPGAISNEYNTGVPYDSMCDLCHGTSYRYCRRDASEEYYGHTGAFRCLVEGGGHVAFMKHTTVMESTGGKRKEWWARNALNDDFELLCTDGTRAEIQDYKRCNLGKVKANAVVTRGGVNYNETQMNAYINLLTYAQQLYGRKEVDAFSFSMFSSPIGHYDLIFQDATRQLQVIPPNKRRYDAYLGSDFMRARRITDCYAGASQLALSVGLLLVGSLVAML", "length": 819 }, "evidence": [ { "id": "E1BG25", "url": "https://omabrowser.org/oma/group/E1BG25/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of plasminogen activation", "id": "GO:0010756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010756", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "pmid": "" }, { "name": "negative regulation of substrate adhesion-dependent cell spreading", "id": "GO:1900025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900025", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "pmid": "" }, { "name": "positive regulation of extracellular matrix disassembly", "id": "GO:0090091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090091", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "E1BG25", "url": "https://www.uniprot.org/uniprotkb/E1BG25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BG25-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 739, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BG25-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BG25" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BG25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG25" }, { "id": "PS51408", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51408" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transferrin-like", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 357, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 460, "end_pos": 462 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG29-1", "uniprot_ac": "E1BG29", "uniprot_id": "E1BG29_BOVIN", "mass": { "chemical_mass": 59657.0, "monoisotopic_mass": 59657.0 }, "refseq": { "ac": "XP_024850825", "name": "platelet glycoprotein V", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850825" }, "gene_names": [ { "name": "GP5", "type": "recommended", "evidence": [ { "id": "E1BG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG29" } ] }, { "name": "GP5", "type": "synonym", "evidence": [ { "id": "XP_024850825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850825" } ] } ], "protein_names": [ { "name": "Platelet glycoprotein V", "type": "recommended", "evidence": [ { "id": "E1BG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG29/entry#names_and_taxonomy" } ] }, { "name": "Glycoprotein 5", "type": "synonym", "evidence": [ { "id": "E1BG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG29/entry#names_and_taxonomy" } ] }, { "name": "platelet glycoprotein V", "type": "synonym", "evidence": [ { "id": "XP_024850825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850825" } ] } ], "function": [ { "annotation": "The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.", "evidence": [ { "database": "UniProtKB", "id": "E1BG29", "url": "https://www.uniprot.org/uniprotkb/E1BG29#function" }, { "database": "UniProtKB", "id": "ARBA00059450", "url": "https://www.uniprot.org/uniprotkb/ARBA00059450#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG29", "url": "https://www.uniprot.org/uniprotkb/E1BG29" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GP5", "url": "https://www.uniprot.org/uniprotkb/E1BG29", "locus": { "chromosome": "1", "start_pos": 73137346, "end_pos": 73131219, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013203", "url": "https://www.ensembl.org/id/ENSBTAG00000013203" } ] } } ], "crossref": [ { "id": "E1BG29", "url": "https://alphafold.ebi.ac.uk/entry/E1BG29", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013203", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013203", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "522692", "url": "https://www.ncbi.nlm.nih.gov/gene/522692", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:522692", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522692", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HILLFGM", "url": "https://omabrowser.org/oma/group/HILLFGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BG29", "url": "https://www.orthodb.org/?gene=E1BG29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": 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"url": "https://www.ensembl.org/id/ENSBTAP00000017571.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:522692", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522692", "resource": "KEGG Pathway" }, { "id": "R-BTA-430116", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-430116", "resource": "Reactome", "description": "GP1b-IX-V activation signalling" }, { "id": "R-BTA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" }, { "id": "R-BTA-9769743", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769743", "resource": "Reactome", "description": "Amplification and propagation of coagulation cascade" }, { "id": "R-BTA-9935598", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9935598", "resource": "Reactome", "description": "FXIIa, PKa-dependent activation of coagulation pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O08742-1", "protein_name": "Platelet glycoprotein V", "gene_name": "Gp5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRSALLSAVLPLLRAQPFPCPKTCKCVVRDAAQCSGGSVAHIAELGLPTNLTHILLFRMDQGILRNHSFSGMTVLQRQMLSDSHISAIDPGTFNDLVKLKTLRLTRNKISRLPRAILDKMVLLEQLFLDHNALRDLDQNLFQQLRNLQELGLNQNQLSFLPANLFSSLRELKLLDLSRNNLTHLPKGLLGAQVKLEKLLLYSNQLTSVDSGLLSNLGALTELRLERNHLRSVAPGAFDRLGNLSSLTLSGNLLESLPPALFLHVSSVSRLTLFENPLEELPDVLFGEMAGLRELWLNGTHLSTLPAAAFRNLSGLQTLGLTRNPRLSALPRGVFQGLRELRVLGLHTNALAELRDDALRGLGHLRQVSLRHNRLRALPRTLFRNLSSLESVQLEHNQLETLPGDVFAALPQLTQVLLGHNPWLCDCGLWRFLQWLRHHPDILGRDEPPQCRGPEPRASLSFWELLQGDPWCPDPRSLPLDPPTENALEAPVPSWLPNSWQSQTWAQLVARGESPNNRLYWGLYILLLVAQAIIAAFIVFAMIKIGQLFRTLIREKLLLEAMGKSCN", "length": 567 }, "evidence": [ { "id": "E1BG29", "url": "https://omabrowser.org/oma/group/E1BG29/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O08770-1", "protein_name": "Platelet glycoprotein V", "gene_name": "Gp5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRSVLLSAVLSLVGAQPFPCPKTCKCVVRDAVQCSGGSVAHIAELGLPTNLTHILLFRMDRGVLQSHSFSGMTVLQRLMLSDSHISAIDPGTFNDLVKLKTLRLTRNKISHLPRAILDKMVLLEQLFLDHNALRDLDQNLFQKLLNLRDLCLNQNQLSFLPANLFSSLGKLKVLDLSRNNLTHLPQGLLGAQIKLEKLLLYSNRLMSLDSGLLANLGALTELRLERNHLRSIAPGAFDSLGNLSTLTLSGNLLESLPPALFLHVSWLTRLTLFENPLEELPEVLFGEMAGLRELWLNGTHLRTLPAAAFRNLSGLQTLGLTRNPLLSALPPGMFHGLTELRVLAVHTNALEELPEDALRGLGRLRQVSLRHNRLRALPRTLFRNLSSLVTVQLEHNQLKTLPGDVFAALPQLTRVLLGHNPWLCDCGLWPFLQWLRHHLELLGRDEPPQCNGPESRASLTFWELLQGDQWCPSSRGLPPDPPTENALKAPDPTQRPNSSQSWAWVQLVARGESPDNRFYWNLYILLLIAQATIAGFIVFAMIKIGQLFRTLIREELLFEAMGKSSN", "length": 567 }, "evidence": [ { "id": "E1BG29", "url": "https://omabrowser.org/oma/group/E1BG29/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P40197-1", "protein_name": "Platelet glycoprotein V", 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"https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "E1BG29", "url": "https://www.uniprot.org/uniprotkb/E1BG29" } ], "pmid": "" }, { "name": "blood coagulation, intrinsic pathway", "id": "GO:0007597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007597", "evidence": [ { "database": "UniProtKB", "id": "E1BG29", "url": "https://www.uniprot.org/uniprotkb/E1BG29" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "E1BG29", "url": "https://www.uniprot.org/uniprotkb/E1BG29" } ], "pmid": "" }, { "name": "positive regulation of platelet activation", "id": "GO:0010572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010572", "evidence": [ { "database": "UniProtKB", "id": "E1BG29", "url": "https://www.uniprot.org/uniprotkb/E1BG29" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, 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"start_pos": 181, "end_pos": 183 }, { "start_pos": 267, "end_pos": 269 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519183", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519183", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAQMFFY", "url": "https://omabrowser.org/oma/group/MAQMFFY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003586588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586588", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BG35", "url": "https://www.uniprot.org/uniprotkb/E1BG35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG35-1", "url": "https://www.uniprot.org/uniprotkb/E1BG35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGANLSQGTEFELLGLTSDPWLQKLLFVVFLGMYTITLLGNLIMFLLIHVSTTLHTPMYSLLKSLSFLDFCYSSTVVPQTLVNFLAKRKVITYLGCVVQMFFYAGFATSECYLIAAMAYDRYAAVCNPLLYPIAMSPTVCASLIVGSYGAGFLNSLIHTSCIFSLKFCGTHVVTHFFCDGPPILSLSCVDTSLCEILLFIFAGFNLLSCTLTILVSYLLILITILRMNSAQGRFKAFSTCASHFTAVCLFYGTTLFMYLRPRSSYSLTQDHTVAVIYTVVIPLLNPLIYSLRNKDVKEALRKVWERKIME", "length": 311, "header": "tr|E1BG35-1|E1BG35_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR5AU1 PE=3 SV=2 CANONICAL=E1BG35-1" }, "isoforms": [ { "isoform_ac": "E1BG35-1", "url": "https://www.uniprot.org/uniprotkb/E1BG35/entry#E1BG35-1", "sequence": { "sequence": "MEGANLSQGTEFELLGLTSDPWLQKLLFVVFLGMYTITLLGNLIMFLLIHVSTTLHTPMYSLLKSLSFLDFCYSSTVVPQTLVNFLAKRKVITYLGCVVQMFFYAGFATSECYLIAAMAYDRYAAVCNPLLYPIAMSPTVCASLIVGSYGAGFLNSLIHTSCIFSLKFCGTHVVTHFFCDGPPILSLSCVDTSLCEILLFIFAGFNLLSCTLTILVSYLLILITILRMNSAQGRFKAFSTCASHFTAVCLFYGTTLFMYLRPRSSYSLTQDHTVAVIYTVVIPLLNPLIYSLRNKDVKEALRKVWERKIME", "length": 311, "header": "tr|E1BG35-1|E1BG35_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR5AU1 PE=3 SV=2 CANONICAL=E1BG35-1" }, "locus": { "chromosome": "10", "start_pos": 25951711, "end_pos": 25950779, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025176.6", "url": "https://www.ensembl.org/id/ENSBTAT00000025176.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025176.5", "url": "https://www.ensembl.org/id/ENSBTAP00000025176.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:519183", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519183", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M7W5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100752638", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MERTNLSQEMEFELLGLTSDPQLQRLLFVVFLAMYSITVLGNLIMFWLIHVSVTLHTPMYSLLKSLSFLDFCYSSTVVPQTLMNFLAKRKVISYLGCMAQMFFYAGFATSECYLIAAMAYDRYVAVCNPLLYPTIMSPNVCASLIVGSYSAGFLNSLIHTSCIFSLNFCGAHVVTHFFCDGPPILSLSCVDTSLCEILLFIFAGFNLLSCTLTILISYFLILITVLQMNSSQGRFKAFSTCSSHLTAVCFFFGTTLFMYLRPKSSYSLTQDRTVAVIYTVVIPMLNPLIYSLRNKDVKEALRKVWGWRSIE", "length": 311 }, "evidence": [ { "id": "E1BG35", "url": "https://omabrowser.org/oma/group/E1BG35/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BG35", "url": "https://www.uniprot.org/uniprotkb/E1BG35" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "E1BG35", "url": "https://www.uniprot.org/uniprotkb/E1BG35" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "E1BG35", "url": "https://www.uniprot.org/uniprotkb/E1BG35" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BG35", "url": "https://www.uniprot.org/uniprotkb/E1BG35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BG35-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BG35-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BG35" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG35" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG42-1", "uniprot_ac": "E1BG42", "uniprot_id": "E1BG42_BOVIN", "mass": { "chemical_mass": 38602.0, "monoisotopic_mass": 38602.0 }, "refseq": { "ac": "NP_001179889", "name": "calcium homeostasis modulator protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179889" }, "gene_names": [ { "name": "CALHM3", "type": "recommended", "evidence": [ { "id": "E1BG42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG42" } ] }, { "name": "CALHM3", "type": "synonym", "evidence": [ { "id": "NP_001179889", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179889" } ] } ], "protein_names": [ { "name": "Calcium homeostasis modulator 3", "type": "synonym", "evidence": [ { "id": "E1BG42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG42/entry#names_and_taxonomy" } ] }, { "name": "calcium homeostasis modulator protein 3", "type": "synonym", "evidence": [ { "id": "NP_001179889", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179889" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG42", "url": "https://www.uniprot.org/uniprotkb/E1BG42" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CALHM3", "url": "https://www.uniprot.org/uniprotkb/E1BG42", "locus": { "chromosome": "26", "start_pos": 24058918, "end_pos": 24067709, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000032761", "url": "https://www.ensembl.org/id/ENSBTAG00000032761" } ] } } ], "crossref": [ { "id": "E1BG42", "url": "https://alphafold.ebi.ac.uk/entry/E1BG42", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000032761", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000032761", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613539", "url": "https://www.ncbi.nlm.nih.gov/gene/613539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613539", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613539", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCWSQAL", "url": "https://omabrowser.org/oma/group/RCWSQAL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BG42", "url": "https://www.orthodb.org/?gene=E1BG42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179889", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179889", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BG42", "url": "https://www.uniprot.org/uniprotkb/E1BG42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG42-1", "url": "https://www.uniprot.org/uniprotkb/E1BG42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKFRTLFLHFQSSSESVMNGVCLLLAMVTVKLYSSFDFNCPCLARYNALYGLGLLFTPPIALFLCGLLANRQSVVMVEEWRRPAGHRRKDPGIVRYMCSSVLQRALAAPVIWILLALLDGKCFVCAFSSSVDPEKFLDFTNMTPSQVQLFLAKVPCKEDELVRNSPARKAVSRYLRCLSQAIGWSLTLLLILLAFLARCLRPCFDQTVFLQRRYWSNYVDLEQKLFDETCCEHARDFAHRCVLHFFASMQSEMQARGLRRDSAGRGPEAPERPEPPDGLDGGSGKAHLRAVSSQEQVDRLLSAWYSSKPPLDLTASSGLWGCGLTHRAPTVVPGTRESPHTDV", "length": 344, "header": "tr|E1BG42-1|E1BG42_BOVIN Isoform 1 of Calcium homeostasis modulator 3 OS=Bos taurus OX=9913 GN=CALHM3 PE=3 SV=1 CANONICAL=E1BG42-1" }, "isoforms": [ { "isoform_ac": "E1BG42-1", "url": "https://www.uniprot.org/uniprotkb/E1BG42/entry#E1BG42-1", "sequence": { "sequence": "MDKFRTLFLHFQSSSESVMNGVCLLLAMVTVKLYSSFDFNCPCLARYNALYGLGLLFTPPIALFLCGLLANRQSVVMVEEWRRPAGHRRKDPGIVRYMCSSVLQRALAAPVIWILLALLDGKCFVCAFSSSVDPEKFLDFTNMTPSQVQLFLAKVPCKEDELVRNSPARKAVSRYLRCLSQAIGWSLTLLLILLAFLARCLRPCFDQTVFLQRRYWSNYVDLEQKLFDETCCEHARDFAHRCVLHFFASMQSEMQARGLRRDSAGRGPEAPERPEPPDGLDGGSGKAHLRAVSSQEQVDRLLSAWYSSKPPLDLTASSGLWGCGLTHRAPTVVPGTRESPHTDV", "length": 344, "header": "tr|E1BG42-1|E1BG42_BOVIN Isoform 1 of Calcium homeostasis modulator 3 OS=Bos taurus OX=9913 GN=CALHM3 PE=3 SV=1 CANONICAL=E1BG42-1" }, "locus": { "chromosome": "26", "start_pos": 24065042, "end_pos": 24059301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046123.3", "url": "https://www.ensembl.org/id/ENSBTAT00000046123.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043449.1", "url": "https://www.ensembl.org/id/ENSBTAP00000043449.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:613539", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613539", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BAL1-1", "protein_name": "Calcium homeostasis modulator 3", "gene_name": "CALHM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDKFRMLFQHFQSSSESVMNGICLLLAAVTVKLYSSFDFNCPCLARYNALYGLGLLLTPPLALFLCGLLANRQSVVMVEEWRRPTGHRRKDPGIIRYMCSSVLQRALAAPLVWILLALLDGKCFVCAFSSSVDPEKFLDFANMTPSQVQLFLAKVPCKEDELVRNSPARKAVSRYLRCLSQAIGWSITLLLIVVAFLARCLRPCFDQTVFLQRRYWSNYVDLEQKLFDETCCEHARDFAHRCVLHFFASMQSEMRARGLRRDSASQDPEPLEMPEPPEGLDGGSRKAHLRAVSSREQVNHLLSTWYSRKPPLDLLASPGLWGGGLSHRTPTVAPGTRLSQHTDV", "length": 344 }, "evidence": [ { "id": "E1BG42", "url": "https://omabrowser.org/oma/group/E1BG42/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZGF7-1", "protein_name": "Calcium homeostasis modulator 3", "gene_name": "CALHM3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDRFRMIFQYFQSNSESVMNGICGLLALASVKIYTCLDFSCPCLPHYNMAYGLGIMFVPPIALFLCGLILNRQSLVMLEEWRRPQGHRRKDLAVIRYMCCSIMQRAMVAPAVWIVVTLLDGKCLICAFSGSVDPKKFVGFANATLAQAQEMLSRVPCKEDELMRNSTSRRAVSRYLRCWSQALGWSILLILIIAVFLARWLAPCFNQAALLQTRHWSNYIDIEQKIFEETCCEHSRLFAHQCILHFFESMRKEIRQHSFDLPREKEGEEDLLQGITDRDQVNKLLKMWYYEKPPLDVSQVTHRHPLGQERSPPPCAGSCGARSKFTQHTHM", "length": 331 }, "evidence": [ { "id": "E1BG42", "url": "https://omabrowser.org/oma/group/E1BG42/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A158-1", "protein_name": "Calcium homeostasis modulator 3", "gene_name": "Calhm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRFRMLFQNFQSSSESVTNGICLLLAAVTVKMYSSLDFNCPCLEHYNALYGLGLLLTPPLALFLCGLLVNRQSVLMVEEWRRPAGHRRKDLGIIRYMCSSVLQRALAAPLVWILLALLDGKCLVCAFSNSVDPEKFLDFANMTPSQVQLFLAKVPCKEDELVKTSPARKAVSRYLRCLSQAIGWSITLLVIVVAFLARCLRPCFNQTVFLQRRYWSNYMDLEQKLFDETCCEHARDFAHRCVLHFFASMQSELRALGLHRDPAGEILESQEPPEPPEEPGSESGKAHLRAISSREQVNHLLSTWYSSKPPLDLAASPRLWEPGLNHRAPIAAPGTKLGHQLDV", "length": 344 }, "evidence": [ { "id": "E1BG42", "url": "https://omabrowser.org/oma/group/E1BG42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FFW5-1", "protein_name": "Calcium homeostasis modulator protein 3", "gene_name": "calhm3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDRLKLVLQYFQSNSESISNGICIILSLISVKLYTSFDFNCPCLPQYNKMYAMGVMFVPPIILLLLGVLVNRHTGVLMEEWVRPLGKRAKNPAVVKFLLSSMMQRALLAPMVWILMTLLDGKCFICAFSMNVDPKYFTGIPNSTGLELVKIMAKVPCKEDVIFRNSSFRKAVSRYVRCYSQAIGWSILLFLIFLGAVARVIKPCFNHATFLQTRYWSNYLDMEQKLFDETCVLHARDFARKSVLQFFENMRENVTVRMPLSSAPRYSTVQNEFGEEEEERLHGITRQDQVDHLLQTWYECKPELDVTKMAYKPKACITWEDHSGRPLFSDV", "length": 331 }, "evidence": [ { "id": "E1BG42", "url": "https://omabrowser.org/oma/group/E1BG42/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "J3QMI4-1", "protein_name": "Calcium homeostasis modulator protein 3", "gene_name": "Calhm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRFRMLFQHLQSSSESVMNGICLLLAAVTVKIYSSLDFNCPCLERYNALYGLGLLLTPPLALFLCGLLVNRQSVLMVEEWRRPAGHRRKDLGIIRYMCSSVLQRALAAPLVWILLALLDGKCFVCAFSNSVDPEKFLDFANMTPRQVQLFLAKVPCKEDELVKNSPARKAVSRYLRCLSQAIGWSITLLVIVVAFLARCLRPCFDQTVFLQRRYWSNYMDLEQKLFDETCCEHARDFAHRCVLHFFANMQSELRALGLRRDPAGGIPESQESSEPPELREDRDSGNGKAHLRAISSREQVDQLLSTWYSSKPPLDLAASPRRWGPGLNHRAPIAAPGTKLCHQLNV", "length": 347 }, "evidence": [ { "id": "E1BG42", "url": "https://omabrowser.org/oma/group/E1BG42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86XJ0-1", "protein_name": "Calcium homeostasis modulator protein 3", "gene_name": "CALHM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDKFRMLFQHFQSSSESVMNGICLLLAAVTVKLYSSFDFNCPCLVHYNALYGLGLLLTPPLALFLCGLLANRQSVVMVEEWRRPAGHRRKDPGIIRYMCSSVLQRALAAPLVWILLALLDGKCFVCAFSSSVDPEKFLDFANMTPSQVQLFLAKVPCKEDELVRDSPARKAVSRYLRCLSQAIGWSVTLLLIIAAFLARCLRPCFDQTVFLQRRYWSNYVDLEQKLFDETCCEHARDFAHRCVLHFFASMRSELQARGLRRGNAGRRLELPAVPEPPEGLDSGSGKAHLRAISSREQVDRLLSTWYSSKPPLDLAASPGLCGGGLSHRAPTLALGTRLSQHTDV", "length": 344 }, "evidence": [ { "id": "E1BG42", "url": "https://omabrowser.org/oma/group/E1BG42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BG42", "url": "https://www.uniprot.org/uniprotkb/E1BG42" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "E1BG42", "url": "https://www.uniprot.org/uniprotkb/E1BG42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein heterooligomerization", "id": "GO:0051291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051291", "evidence": [ { "database": "UniProtKB", "id": "E1BG42", "url": "https://www.uniprot.org/uniprotkb/E1BG42" } ], "pmid": "" }, { "name": "sensory perception of taste", "id": "GO:0050909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050909", "evidence": [ { "database": "UniProtKB", "id": "E1BG42", "url": "https://www.uniprot.org/uniprotkb/E1BG42" } ], "pmid": "" }, { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "E1BG42", "url": "https://www.uniprot.org/uniprotkb/E1BG42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "voltage-gated monoatomic ion channel activity", "id": "GO:0005244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005244", "evidence": [ { "database": "UniProtKB", "id": "E1BG42", "url": "https://www.uniprot.org/uniprotkb/E1BG42" } ], "pmid": "" }, { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "E1BG42", "url": "https://www.uniprot.org/uniprotkb/E1BG42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BG42-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 344, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BG42-F1.pdb", "url_external": 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"reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "POM121C", "url": "https://www.uniprot.org/uniprotkb/E1BG57", "locus": {} } ], "crossref": [ { "id": "E1BG57", "url": "https://alphafold.ebi.ac.uk/entry/E1BG57", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017939", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017939", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "518768", "url": "https://www.ncbi.nlm.nih.gov/gene/518768", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:518768", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518768", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VCCIVCY", "url": "https://omabrowser.org/oma/group/VCCIVCY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { 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"length": 1216, "header": "tr|E1BG57-1|E1BG57_BOVIN Isoform 1 of POM121 transmembrane nucleoporin C OS=Bos taurus OX=9913 GN=POM121C PE=4 SV=2 CANONICAL=E1BG57-1" }, "locus": { "chromosome": "25", "start_pos": 33844327, "end_pos": 33827897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023854.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023854.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023854.5", "url": "https://www.ensembl.org/id/ENSBTAP00000023854.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1121, "start_aa": "Thr", "end_pos": 1121, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1121", "evidence": [ { "id": "", "database": 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"length": 1201 }, "evidence": [ { "id": "E1BG57", "url": "https://omabrowser.org/oma/group/E1BG57/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P52591-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "Pom121", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"length": 1200 }, "evidence": [ { "id": "E1BG57", "url": "https://omabrowser.org/oma/group/E1BG57/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "E1BG57", "url": "https://www.uniprot.org/uniprotkb/E1BG57" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "E1BG57", "url": "https://www.uniprot.org/uniprotkb/E1BG57" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "E1BG57", "url": "https://www.uniprot.org/uniprotkb/E1BG57" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "E1BG57", "url": "https://www.uniprot.org/uniprotkb/E1BG57" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "E1BG57", "url": "https://www.uniprot.org/uniprotkb/E1BG57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BG57-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1216, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BG57-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BG57" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 472, 985, 989, 1121, 1173 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 267, "end_pos": 269 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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"end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"https://www.ncbi.nlm.nih.gov/protein/XP_003586276", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BG70", "url": "https://www.uniprot.org/uniprotkb/E1BG70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG70-1", "url": "https://www.uniprot.org/uniprotkb/E1BG70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPDELTEPGRATPARASSFLIENLLAAEAKGAGSGAQGGGGREEEEDDDDDPEDEDAERARRRRLQRRRQLRAGSGPSGEARARALLGPGALGLGPRPPLGPGPPYALGCGGAARWYSRSHGGYGGGLSPDTSDRDSPETGEEMGRAEGAWPRGSGPRAVQREAAELAARGPAAGAEEAAELAEAPVATAAAGEARGGGGGRKKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAASLSPPGTQRLVRVPVLYHESSPAAGAAAAAALPFPLAPAAPAPPPPLLGFSGALAYPLAAFPAAASAPFLRAQMPGLV", "length": 347, "header": "tr|E1BG70-1|E1BG70_BOVIN Isoform 1 of H6 family homeobox 1 OS=Bos taurus OX=9913 GN=HMX1 PE=3 SV=3 CANONICAL=E1BG70-1" }, "isoforms": [ { "isoform_ac": "E1BG70-1", "url": "https://www.uniprot.org/uniprotkb/E1BG70/entry#E1BG70-1", "sequence": { "sequence": "MPDELTEPGRATPARASSFLIENLLAAEAKGAGSGAQGGGGREEEEDDDDDPEDEDAERARRRRLQRRRQLRAGSGPSGEARARALLGPGALGLGPRPPLGPGPPYALGCGGAARWYSRSHGGYGGGLSPDTSDRDSPETGEEMGRAEGAWPRGSGPRAVQREAAELAARGPAAGAEEAAELAEAPVATAAAGEARGGGGGRKKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAASLSPPGTQRLVRVPVLYHESSPAAGAAAAAALPFPLAPAAPAPPPPLLGFSGALAYPLAAFPAAASAPFLRAQMPGLV", "length": 347, "header": "tr|E1BG70-1|E1BG70_BOVIN Isoform 1 of H6 family homeobox 1 OS=Bos taurus OX=9913 GN=HMX1 PE=3 SV=3 CANONICAL=E1BG70-1" }, "locus": { "chromosome": "6", "start_pos": 115036013, "end_pos": 115032116, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056515.4", "url": "https://www.ensembl.org/id/ENSBTAT00000056515.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051029.3", "url": "https://www.ensembl.org/id/ENSBTAP00000051029.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 12, "start_aa": "Thr", "end_pos": 12, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr12", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:785113", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785113", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZBP8-1", "protein_name": "H6 family homeobox 1", "gene_name": "Hmx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPDELTEPGRATPARASSFLIENLLAAEAKGSGRAAQGDGVREEEEEDDDDPEDEDPEQARRRRLQRRRQQRAGSGPGGEARARALGLGPRPPPGPGPPFALGCGGATRWYPRAQGGYGGGLSPDTSDRDSPETGEDMGRAESAWPRCPGPGAVPREVTTQGPAAGGEEAAELAEAPAVAAAAAGEARGGRRKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAASLSPPGAQRLVRVPVLYHESPPAATGPTLPFPLAPPAPAPPPPLLGFSGALAYPLAAFPAAASVPFLRAQMPGLV", "length": 333 }, "evidence": [ { "id": "E1BG70", "url": "https://omabrowser.org/oma/group/E1BG70/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O70218-1", "protein_name": "Homeobox protein HMX1", "gene_name": "Hmx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPDELTEPGRATPARASSFLIENLLAAEAKGAGRSTQGDGVREEEEEDDDDPEDEDPEQARRRLQRRRQQRAGSGPGGEARARALGLGPRPPPGPGPPFALGCGGTTRWYPRVHGGYGGGLSPDTSDRDSPETGEEMGRAESAWPRCPGPGTVPREVTTQGPATGGEEAAELAEAPAVAAAATGEARGGRRKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAASLSPPGAQRLVRVPVLYHESPPAAAGPALPFPLAPPAPAPPPPLLGFSGALAYPLAAFPAAASVPFLRAQMPGLV", "length": 332 }, "evidence": [ { "id": "E1BG70", "url": "https://omabrowser.org/oma/group/E1BG70/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP08-1", "protein_name": "Homeobox protein HMX1", "gene_name": "HMX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPDELTEPGRATPARASSFLIENLLAAEAKGAGRATQGDGSREDEEEDDDDPEDEDAEQARRRRLQRRRQLLAGTGPGGEARARALLGPGALGLGPRPPPGPGPPFALGCGGAARWYPRAHGGYGGGLSPDTSDRDSPETGEEMGRAEGAWPRGPGPGAVQREAAELAARGPAAGTEEASELAEVPAAAGETRGGVGVGGGRKKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAASLSPPGAQRLVRVPVLYHESPPAAAAAGPPATLPFPLAPAAPAPPPPLLGFSGALAYPLAAFPAAASVPFLRAQMPGLV", "length": 348 }, "evidence": [ { "id": "E1BG70", "url": "https://omabrowser.org/oma/group/E1BG70/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BG70", "url": "https://www.uniprot.org/uniprotkb/E1BG70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BG70", "url": "https://www.uniprot.org/uniprotkb/E1BG70" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BG70", "url": "https://www.uniprot.org/uniprotkb/E1BG70" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "E1BG70", "url": "https://www.uniprot.org/uniprotkb/E1BG70" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "E1BG70", "url": "https://www.uniprot.org/uniprotkb/E1BG70" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BG70", "url": "https://www.uniprot.org/uniprotkb/E1BG70" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BG70", "url": "https://www.uniprot.org/uniprotkb/E1BG70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BG70-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 347, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BG70-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BG70" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG70" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 201, "end_pos": 261, "start_aa": "Gly", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 12 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BG77-1", "uniprot_ac": "E1BG77", "uniprot_id": "E1BG77_BOVIN", "mass": { "chemical_mass": 82519.0, "monoisotopic_mass": 82519.0 }, "refseq": {}, "gene_names": [ { "name": "ADAM32", "type": "recommended", "evidence": [ { "id": "E1BG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG77" } ] } ], "protein_names": [ { "name": "ADAM metallopeptidase domain 32", "type": "synonym", "evidence": [ { "id": "E1BG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG77/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BG77", "url": "https://www.uniprot.org/uniprotkb/E1BG77" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADAM32", "url": "https://www.uniprot.org/uniprotkb/E1BG77", "locus": { "chromosome": "27", "start_pos": 34420189, "end_pos": 34246204, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000023146", "url": "https://www.ensembl.org/id/ENSBTAG00000023146" } ] } } ], "crossref": [ { "id": "E1BG77", "url": "https://alphafold.ebi.ac.uk/entry/E1BG77", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000023146", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000023146", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BG77", "url": "https://www.uniprot.org/uniprotkb/E1BG77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG77-1", "url": "https://www.uniprot.org/uniprotkb/E1BG77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIRLMILLAGLRGLLTSRPDFQNSFLQIILPEKVQANTSESENSEVENKQVSYSISIDEKPYTVHLKQRFFLANNFMVYMYNQGSVNSQSSNIQGQCYYQGYIEGYPNSFVTLSTCSGLRGILQFENVSYGIEPLESAFEFQHLLYKLGNGKNEFTVLTENKEDTEQNPMDYNIFISEKPESTVSTDLIPLYLEMHIVVDKALFDYLGSDSMIVTNKIIEIIGLVNSMFAQLKISIVLSSLELWSDKNKISTAGEAEELLHRFLEWKNSYLTLRPHDIAYLFIFREYPNYVGAAFPGKMCVTGYSAGVALYPKEMTLEAVSVIVTQMLGLSLGISYDDPKKCRCSGAICIMSTKAVQSSGMKTFSDCSLRDFEHFISNVGAQCLQNKPQMQDNPTEICGNGRVEGNEACDCGSEEDCGPDSCCDPLTCLMKPETECSEGSCCDDCQFMEAGAVCRPTAHPECDIPEFCNGSSGMCPADITILNGQECEGGKAYCFDGGCQDIDARCESIFGKGSRNAPFACYEEIQSQTDRFGNCGKSGGKYTFCPWRSLICGRLICTYPLQTPFLRDSASVIYAFVRSTICITMLYETTDAQDALVVKSGSICDKGRICVNRRCSEVGPYINRVNQCSAQCGGNGVCTSRMICNCTEGYAPPNCTTRARISPGAQDLLTKRTSEKGGEKQWLLAIYIALPVLVVATIIVASWKLSKKWFSKKEESQSSGSTSESSSQSDTVRSKSESSPQTNRSSN", "length": 747, "header": "tr|E1BG77-1|E1BG77_BOVIN Isoform 1 of ADAM metallopeptidase domain 32 OS=Bos taurus OX=9913 GN=ADAM32 PE=4 SV=3 CANONICAL=E1BG77-1" }, "isoforms": [ { "isoform_ac": "E1BG77-1", "url": "https://www.uniprot.org/uniprotkb/E1BG77/entry#E1BG77-1", "sequence": { "sequence": "MIRLMILLAGLRGLLTSRPDFQNSFLQIILPEKVQANTSESENSEVENKQVSYSISIDEKPYTVHLKQRFFLANNFMVYMYNQGSVNSQSSNIQGQCYYQGYIEGYPNSFVTLSTCSGLRGILQFENVSYGIEPLESAFEFQHLLYKLGNGKNEFTVLTENKEDTEQNPMDYNIFISEKPESTVSTDLIPLYLEMHIVVDKALFDYLGSDSMIVTNKIIEIIGLVNSMFAQLKISIVLSSLELWSDKNKISTAGEAEELLHRFLEWKNSYLTLRPHDIAYLFIFREYPNYVGAAFPGKMCVTGYSAGVALYPKEMTLEAVSVIVTQMLGLSLGISYDDPKKCRCSGAICIMSTKAVQSSGMKTFSDCSLRDFEHFISNVGAQCLQNKPQMQDNPTEICGNGRVEGNEACDCGSEEDCGPDSCCDPLTCLMKPETECSEGSCCDDCQFMEAGAVCRPTAHPECDIPEFCNGSSGMCPADITILNGQECEGGKAYCFDGGCQDIDARCESIFGKGSRNAPFACYEEIQSQTDRFGNCGKSGGKYTFCPWRSLICGRLICTYPLQTPFLRDSASVIYAFVRSTICITMLYETTDAQDALVVKSGSICDKGRICVNRRCSEVGPYINRVNQCSAQCGGNGVCTSRMICNCTEGYAPPNCTTRARISPGAQDLLTKRTSEKGGEKQWLLAIYIALPVLVVATIIVASWKLSKKWFSKKEESQSSGSTSESSSQSDTVRSKSESSPQTNRSSN", "length": 747, "header": "tr|E1BG77-1|E1BG77_BOVIN Isoform 1 of ADAM metallopeptidase domain 32 OS=Bos taurus OX=9913 GN=ADAM32 PE=4 SV=3 CANONICAL=E1BG77-1" }, "locus": { "chromosome": "27", "start_pos": 34420076, "end_pos": 34246215, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031489.6", "url": "https://www.ensembl.org/id/ENSBTAT00000031489.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000031443.5", "url": "https://www.ensembl.org/id/ENSBTAP00000031443.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "E1BG77", "url": "https://www.uniprot.org/uniprotkb/E1BG77" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BG77", "url": "https://www.uniprot.org/uniprotkb/E1BG77" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E1BG77", "url": "https://www.uniprot.org/uniprotkb/E1BG77" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BG77", "url": "https://www.uniprot.org/uniprotkb/E1BG77" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "E1BG77", "url": "https://www.uniprot.org/uniprotkb/E1BG77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 743, "end_pos": 745, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BG77-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 747, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BG77-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BG77" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG77" }, { "id": "PS50214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disintegrin", "eco_id": "ECO_0000259", "start_pos": 395, "end_pos": 483, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG77" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 624, "end_pos": 656, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG77" }, { "id": "PS50215", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50215" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M12B", "eco_id": "ECO_0000259", "start_pos": 191, "end_pos": 388, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 645, "end_pos": 647 }, { "start_pos": 654, "end_pos": 656 }, { "start_pos": 743, "end_pos": 745 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGA2-1", "uniprot_ac": "E1BGA2", "uniprot_id": "E1BGA2_BOVIN", "mass": { "chemical_mass": 28852.0, "monoisotopic_mass": 28852.0 }, "refseq": { "ac": "NP_001421649", "name": "MIT domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421649" }, "gene_names": [ { "name": "MITD1", "type": "recommended", "evidence": [ { "id": "E1BGA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA2" } ] }, { "name": "MITD1", "type": "synonym", "evidence": [ { "id": "NP_001421649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421649" } ] } ], "protein_names": [ { "name": "MIT domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "E1BGA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA2/entry#names_and_taxonomy" } ] }, { "name": "MIT domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001421649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421649" } ] }, { "name": "MIT, microtubule interacting and transport, domain containing 1", "type": "synonym", "evidence": [ { "id": "NP_001421649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421649" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGA2", "url": "https://www.uniprot.org/uniprotkb/E1BGA2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MITD1", "url": "https://www.uniprot.org/uniprotkb/E1BGA2", "locus": { "chromosome": "11", "start_pos": 4320182, "end_pos": 4336803, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003970", "url": "https://www.ensembl.org/id/ENSBTAG00000003970" } ] } } ], "crossref": [ { "id": "E1BGA2", "url": "https://alphafold.ebi.ac.uk/entry/E1BGA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003970", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003970", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02685", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02685", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "504291", "url": "https://www.ncbi.nlm.nih.gov/gene/504291", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FYKASNP", "url": "https://omabrowser.org/oma/group/FYKASNP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21222:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21222:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16565", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16565", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001421649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BGA2", "url": "https://www.uniprot.org/uniprotkb/E1BGA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGA2-1", "url": "https://www.uniprot.org/uniprotkb/E1BGA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSSLAQDPGSTAALTVLKRALDLESESRGPQALVCYQEGIDLLLQVLKGTKDETKKRNLRKIISDHMDRAEHLKKRLDQEKEAGKYHKQIKIEENATGFSYESLFQEYLSETVTEVWIEDPYIRHTHQLYNFLRFCEMLVKRPCKVKTIHLLTSLDEGTGKDQHSGLEEIKQSLRNHGVSLELEYSSSIHDREIRFNNGWIIKIGRGLDYFKKPQSRFSLGYCDFDLRPCHETTVDIFHNKHTKKI", "length": 248, "header": "tr|E1BGA2-1|E1BGA2_BOVIN Isoform 1 of MIT domain-containing protein 1 OS=Bos taurus OX=9913 GN=MITD1 PE=4 SV=1 CANONICAL=E1BGA2-1" }, "isoforms": [ { "isoform_ac": "E1BGA2-1", "url": "https://www.uniprot.org/uniprotkb/E1BGA2/entry#E1BGA2-1", "sequence": { "sequence": "MSRSSLAQDPGSTAALTVLKRALDLESESRGPQALVCYQEGIDLLLQVLKGTKDETKKRNLRKIISDHMDRAEHLKKRLDQEKEAGKYHKQIKIEENATGFSYESLFQEYLSETVTEVWIEDPYIRHTHQLYNFLRFCEMLVKRPCKVKTIHLLTSLDEGTGKDQHSGLEEIKQSLRNHGVSLELEYSSSIHDREIRFNNGWIIKIGRGLDYFKKPQSRFSLGYCDFDLRPCHETTVDIFHNKHTKKI", "length": 248, "header": "tr|E1BGA2-1|E1BGA2_BOVIN Isoform 1 of MIT domain-containing protein 1 OS=Bos taurus OX=9913 GN=MITD1 PE=4 SV=1 CANONICAL=E1BGA2-1" }, "locus": { "chromosome": "11", "start_pos": 4336799, "end_pos": 4320921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005179.5", "url": "https://www.ensembl.org/id/ENSBTAT00000005179.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005179.3", "url": "https://www.ensembl.org/id/ENSBTAP00000005179.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1P5I2-1", "protein_name": "Microtubule interacting and trafficking domain containing 1", "gene_name": "MITD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRAGGDGTTALERAGAETVKRAVELDLASRFQESLVCYQEGIDLLLQVVKGTKDEAKKQRYRQKISEYMTRAEDIKKHIEKEKQDGKYHKQIKIEENATGFGYEKLFQEYLTEIVSEVWVEDPYIRNVHQLYNFLRFCEMLVKGPCKVRTIHLLTSYDEGNGRNQQTSGLEEIKQSLRNHGITLNVAFSSSIHDREIRFNNGWMIKIGRGLDYFKKPQGRFSIGYCDFDLRPCHETTVDVFHTKHTKKM", "length": 250 }, "evidence": [ { "id": "E1BGA2", "url": "https://omabrowser.org/oma/group/E1BGA2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1STE3-1", "protein_name": "MIT domain-containing protein 1", "gene_name": "MITD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKSGLGPEAGSAAAVTVIKRALELESESRYPQALVCYQEGIDLLLQVLKGTKDETKRCTLRKRISEYMDRAENIKKYLDQEKEAGKYHKQIKIEENATGFSYESLFQEYLSETVTEVWIEDPYIRHTHQLYNFLRFCEMLVKRPCKVKTIHLLTSSEEGIGKEQQSSGLQEIKESLRNHGVLLDLEYSSSIHDREIRFNNGWMIKIGRGLDYFKKPQGRFSLGYCDFDLRPCHETTVDIFHNKHTKKI", "length": 249 }, "evidence": [ { "id": "E1BGA2", "url": "https://omabrowser.org/oma/group/E1BGA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I701-1", "protein_name": "MIT domain-containing protein 1", "gene_name": "Mitd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKSSLGQDSDSTAAVAVLKRAVELDAESRYQQALVCYQEGIDMLLQVLKGTRDSSKRCVLRTKISDYMDRAENIKKYLDQEKEDGKYHKQIKIEENATGFSYETLFKEYLHETVTEVWIEDPYIRQTHQLYNFLRFCEMLIKKPCKIRTIHLLTSVDEGFGNAQQSSGLEEIKQSLRSHGVLLEINYSSSIHDREIRFNTGWMFKIGRGLDYFKRPQGRFSLGYCDLDLRPCHETTVDIFHNKHTKKI", "length": 249 }, "evidence": [ { "id": "E1BGA2", "url": "https://omabrowser.org/oma/group/E1BGA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5I0J5-1", "protein_name": "MIT domain-containing protein 1", "gene_name": "Mitd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKSSLGQDSDSTAAVAVLKRAVELDAESRYQQALVCYQEGIDMLLQVLKGTKESSKRSTLRTKISGYMDRAENIKKYLDQEKEDGKYHKQIKIEENATGFSYESLFREYLQETVTEVWIEDPYIRQTHQLYNFLRFCEMLIKKPCKVRTIHLLTSGDEGFGNTQQSSGLEEIKQSLRSHGVVLEINYSSSIHDREIRFNNGWMIKIGRGLDYFKKPQGRFSLGYCDLDLRPCHETTVDIFHNKHTKKI", "length": 249 }, "evidence": [ { "id": "E1BGA2", "url": "https://omabrowser.org/oma/group/E1BGA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VDV8-1", "protein_name": "MIT domain-containing protein 1", "gene_name": "Mitd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "midbody abscission", "id": "GO:0061952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061952", "evidence": [ { "database": "UniProtKB", "id": "E1BGA2", "url": "https://www.uniprot.org/uniprotkb/E1BGA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGA2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 248, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGA2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGA2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGA2", "database": "UniProtKB", "url": 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"MAAAGAPWSWMVHALIAALILGAKDPVLGNDVASCDDPSAFGPSGSTPDLRPGATEDTRADESSSRIVNGTDCERNSQPWQAALLVRFNKLYCGAVLVDPQWLLTAAHCRKQFFRVRLGHHSLSPMYESGQQLLKGIKSIPHPGYSHPGHSNDLMLIKLNKRIRETPYVRPINIASRCPSAGTSCLVSGWGTTSSPQVTFPKALQCLNITVLSDDQCKKAYPNQIDNTMFCAGDQAGRDSCQGDSGGPVVCNGSLQGLVSWGDFPCAQPNRPGVYTNLCRFTKWIQDTIKCNS", "length": 293, "header": "tr|E1BGD9-1|E1BGD9_BOVIN Isoform 1 of tissue kallikrein OS=Bos taurus OX=9913 GN=KLK5 PE=3 SV=2 CANONICAL=E1BGD9-1" }, "isoforms": [ { "isoform_ac": "E1BGD9-1", "url": "https://www.uniprot.org/uniprotkb/E1BGD9/entry#E1BGD9-1", "sequence": { "sequence": "MAAAGAPWSWMVHALIAALILGAKDPVLGNDVASCDDPSAFGPSGSTPDLRPGATEDTRADESSSRIVNGTDCERNSQPWQAALLVRFNKLYCGAVLVDPQWLLTAAHCRKQFFRVRLGHHSLSPMYESGQQLLKGIKSIPHPGYSHPGHSNDLMLIKLNKRIRETPYVRPINIASRCPSAGTSCLVSGWGTTSSPQVTFPKALQCLNITVLSDDQCKKAYPNQIDNTMFCAGDQAGRDSCQGDSGGPVVCNGSLQGLVSWGDFPCAQPNRPGVYTNLCRFTKWIQDTIKCNS", "length": 293, "header": "tr|E1BGD9-1|E1BGD9_BOVIN Isoform 1 of tissue kallikrein OS=Bos taurus OX=9913 GN=KLK5 PE=3 SV=2 CANONICAL=E1BGD9-1" }, "locus": { "chromosome": "18", "start_pos": 56942157, "end_pos": 56933106, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027772.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027772.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027772.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027772.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 47, "start_aa": "Thr", "end_pos": 47, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr47", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:617418", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617418", "resource": "KEGG Pathway" }, { "id": "R-BTA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZRA7-1", "protein_name": "Kallikrein related-peptidase 5", "gene_name": "Klk5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARAGHPWKWAMATLIATLVLGVSELALADDVASCDNSSGTKPSGTNRDLNTDSNSGEDTRSDSSSRIVNGSDCPKDTQPWQGALLLGPNKLYCGAVLINPQWLLTAAHCRKPVFRIRLGHHSMSPVYESGQQMFQGIKSIPHPGYSHPGHSNDLMLIKMNRKIRASHSVKPVEITSDCPKEGTRCMVSGWGTTSSSHNNFPKVLQCLDITVLSEERCKNSYPGQIDKTMFCAGDEAGRDSCQGDSGGPVICNGKLQGLVSWGDFPCAQPNRPGVYTNLCEFVPWIKDTIHSN", "length": 293 }, "evidence": [ { "id": "E1BGD9", "url": "https://omabrowser.org/oma/group/E1BGD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y337-1", "protein_name": "Kallikrein-5", "gene_name": "KLK5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS", "length": 293 }, "evidence": [ { "id": "E1BGD9", "url": "https://omabrowser.org/oma/group/E1BGD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "E1BGD9", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BGD9", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "E1BGD9", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ], "pmid": "" }, { "name": "epidermal lamellar body", "id": "GO:0097209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097209", "evidence": [ { "database": "UniProtKB", "id": "E1BGD9", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BGD9", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ], "pmid": "" }, { "name": "extracellular matrix disassembly", "id": "GO:0022617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022617", "evidence": [ { "database": "UniProtKB", "id": "E1BGD9", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ], "pmid": "" }, { "name": "positive regulation of G protein-coupled receptor signaling pathway", "id": "GO:0045745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045745", "evidence": [ { "database": "UniProtKB", "id": "E1BGD9", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "E1BGD9", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ], "pmid": "" }, { "name": "amelogenesis", "id": "GO:0097186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097186", "evidence": [ { "database": "UniProtKB", "id": "E1BGD9", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ], "pmid": "" }, { "name": "antibacterial peptide biosynthetic process", "id": "GO:0002780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002780", "evidence": [ { "database": "UniProtKB", "id": "E1BGD9", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-8849638", "name": "Dissociation of the SPINK5:KLK5 complex at low pH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BGD9-1" ], "evidence": [ { "id": "R-BTA-8849638", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8849638" } ] }, { "id": "R-BTA-8849646", "name": "SPINK5(490-624) binds KLK5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BGD9-1" ], "evidence": [ { "id": "R-BTA-8849646", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8849646" } ] }, { "id": "R-BTA-8849857", "name": "KLK5 cleaves and activates CELA2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-BTA-8849859" ], "output_participant_list": [ "R-BTA-8849616", "R-BTA-8849856" ], "enzyme_list": [ "E1BGD9-1" ], "evidence": [ { "id": "R-BTA-8849857", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8849857" } ] }, { "id": "R-BTA-8850794", "name": "SPINK6 binds KLK5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BGD9-1" ], "evidence": [ { "id": "R-BTA-8850794", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8850794" } ] }, { "id": "R-BTA-8850818", "name": "SPINK9 binds KLK5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BGD9-1" ], "evidence": [ { "id": "R-BTA-8850818", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8850818" } ] }, { "id": "R-BTA-8850831", "name": "KLK5 cleaves and activates KLK8", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-BTA-8850832" ], "output_participant_list": [ "R-BTA-8850829", "R-BTA-8850833" ], "enzyme_list": [ "E1BGD9-1", "E1BKC5-1" ], "evidence": [ { "id": "R-BTA-8850831", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8850831" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-8849616", "participant_name": "ELA2A [extracellular region]", "crossref": [ { "id": "ENSBTAG00000024496", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000034039", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000033941", "database": "ENSEMBL", "url": "" }, { "id": "A7YWU4", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-BTA-8849856", "participant_name": "ELA2A [extracellular region]", "crossref": [ { "id": "ENSBTAG00000024496", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000034039", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000033941", "database": "ENSEMBL", "url": "" }, { "id": "A7YWU4", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-BTA-8849859", "participant_name": "ELA2A [extracellular region]", "crossref": [ { "id": "A7YWU4", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000024496", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000033941", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000034039", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-BTA-8850829", "participant_name": "KLK8 [extracellular region]", "crossref": [ { "id": "ENSBTAT00000020127", "database": "ENSEMBL", "url": "" }, { "id": "NP_001180118.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAG00000015128", "database": "ENSEMBL", "url": "" }, { "id": "30682", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000020127", "database": "ENSEMBL", "url": "" }, { "id": "E1BKC5", "database": "UniProt", "url": "" }, { "id": "XP_010813403.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-BTA-8850832", "participant_name": "KLK8 [extracellular region]", "crossref": [ { "id": "E1BKC5", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000015128", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000020127", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000020127", "database": "ENSEMBL", "url": "" }, { "id": "XP_010813403.1", "database": "RefSeq", "url": "" }, { "id": "NP_001180118.1", "database": "RefSeq", "url": "" }, { "id": "30682", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-8850833", "participant_name": "KLK8 [extracellular region]", "crossref": [ { "id": "NP_001180118.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAG00000015128", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000020127", "database": "ENSEMBL", "url": "" }, { "id": "30682", "database": "VGNC", "url": "" }, { "id": "XP_010813403.1", "database": "RefSeq", "url": "" }, { "id": "E1BKC5", "database": "UniProt", "url": "" }, { "id": "ENSBTAP00000020127", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BGD9", "gene_name": "KLK5", "activity": [ { "ec_number": "3.4.21.35", "activity": "Preferential cleavage of Arg-|-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa.", "evidence": [ { "id": "E1BGD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ] }, { "ec_number": "3.4.21.35", "activity": "", "evidence": [ { "id": "E1BGD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" } ] } ] }, { "uniprot_ac": "E1BKC5", "gene_name": "KLK8", "activity": [ { "ec_number": "3.4.21.35", "activity": "Preferential cleavage of Arg-|-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa.", "evidence": [ { "id": "E1BKC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ] }, { "ec_number": "3.4.21.35", "activity": "", "evidence": [ { "id": "E1BKC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKC5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGD9" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 290, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.21.35", "ec_name": "Preferential cleavage of Arg-|-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa.", "evidence": [ { "id": "3.4.21.35", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.21.35" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 47 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"https://omabrowser.org/oma/group/E1BGE9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RY08-1", "protein_name": "Complement C1q like 2", "gene_name": "C1QL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALGLLIAVPLLLQAAPPGAAHYEMMGTCRMICDPYSAAPGGGPAGAKAPPPGPSTAALEVMQDLSANPPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDSGRPGLPGLQLTAGAAGSVGVGGGGTGGGGDSEGEVTGALSAAFSGPKIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD", "length": 287 }, "evidence": [ { "id": "E1BGE9", "url": "https://omabrowser.org/oma/group/E1BGE9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7Z5L3-1", "protein_name": "Complement C1q-like protein 2", "gene_name": "C1QL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://omabrowser.org/oma/group/E1BGE9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "postsynaptic density assembly", "id": "GO:0097107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097107", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" }, { "name": "maintenance of synapse structure", "id": "GO:0099558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099558", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" }, { "name": "regulation of synapse maturation", "id": "GO:0090128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090128", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" }, { "name": "trans-synaptic signaling, modulating synaptic transmission", "id": "GO:0099550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099550", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" }, { "name": "neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0099645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099645", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" }, { "name": "synaptic cleft", "id": "GO:0043083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043083", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" }, { "name": "hippocampal mossy fiber to CA3 synapse", "id": "GO:0098686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098686", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" }, { "name": "cerebellar climbing fiber to Purkinje cell synapse", "id": "GO:0150053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150053", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BGE9", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGE9" }, { "id": "PS50871", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50871" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C1q", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 287, "start_aa": "Phe", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGF9-1", "uniprot_ac": "E1BGF9", "uniprot_id": "E1BGF9_BOVIN", "mass": { "chemical_mass": 101615.0, "monoisotopic_mass": 101615.0 }, "refseq": { "ac": "XP_002692510", "name": "zinc fingers and homeoboxes protein 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692510" }, "gene_names": [ { "name": "ZHX3", "type": "recommended", "evidence": [ { "id": "E1BGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGF9" } ] }, { "name": "ZHX3", "type": "synonym", "evidence": [ { "id": "XP_002692510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692510" } ] } ], "protein_names": [ { "name": "Zinc fingers and homeoboxes protein 3", "type": "recommended", "evidence": [ { "id": "E1BGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGF9/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger and homeodomain protein 3", "type": "synonym", "evidence": [ { "id": "E1BGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGF9/entry#names_and_taxonomy" } ] }, { "name": "zinc fingers and homeoboxes protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_002692510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692510" } ] } ], "function": [ { "annotation": "Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA.", "evidence": [ { "database": "UniProtKB", "id": "E1BGF9", "url": "https://www.uniprot.org/uniprotkb/E1BGF9#function" }, { "database": "UniProtKB", "id": "ARBA00059166", "url": "https://www.uniprot.org/uniprotkb/ARBA00059166#function" }, { "database": "UniProtKB", "id": "A0ABI0NPU6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPU6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGF9", "url": "https://www.uniprot.org/uniprotkb/E1BGF9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZHX3", "url": "https://www.uniprot.org/uniprotkb/E1BGF9", "locus": { "chromosome": "13", "start_pos": 69831956, "end_pos": 69896932, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017594", "url": "https://www.ensembl.org/id/ENSBTAG00000017594" } ] } } ], "crossref": [ { "id": "E1BGF9", "url": "https://alphafold.ebi.ac.uk/entry/E1BGF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017594", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017594", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512451", "url": "https://www.ncbi.nlm.nih.gov/gene/512451", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512451", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512451", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACEPEDD", "url": "https://omabrowser.org/oma/group/ACEPEDD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGF9", "url": "https://www.orthodb.org/?gene=E1BGF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15467", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15467", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15467:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15467:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18387", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18387", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002692510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692510", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NPU6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPU6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGF9", "url": "https://www.uniprot.org/uniprotkb/E1BGF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGF9-1", "url": "https://www.uniprot.org/uniprotkb/E1BGF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKRKSTTPCMIPVKTVVLPGSSAEAPPAEPGPEGPPQEPPPEAPATSTEATQGASGPDVPSLANGHRGTLDGYAYACKYCDFRSQDITQFVGHLSSEHTDFNKDPSFVCTECSFLAKTPEGLSLHNAKCHSGEANFVWNVTKPDNHVVVEQSVPEGGSPPDLSGEPNVEGMDGQAEIIITKTPIMKIMKGKAEAKKIHTLKENVPNQPTGDALPNPPAGDTEVKEGDHASVNGAAPSSQASTNPAKPPHSANGPLLGTVPVLPAGIAQLLSLQQPPPQAQQPLPTARSLPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASSGNVQHLIQAALPGHVVGQPEGTAGGLLVTQPLMANGLQAPSSALPLAVTSVPKPPAVAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDASIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSAREVRKWFSDRRYHCRNLKGARAALSGEHGSLLVDPVPEAPFSPPCKAPEVTCLPTAATLATPPSAKRQSWHQTPDFTPTKYKERAPEQLRALESSFAQNPLPLDEELDRLRTETKMTRREIDGWFSERRKKVSAEEAKKAEEGASPGEEEAAETEGEEGLAGENGSPEVPGGHTLAERKVSPIKINLKNLRVTEANGRGELVGLGICEPEDEAPGKLAEQPPGKAGCKKTAQQRHLLRQLFVQTQWPSTQDYGSIVAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPSNRELLQDYYVTHKMLYEQDLQSLCDKTQMSAQQVKQWFAEKLGEETRAVADTGSEGQGPCAGDPAALHKGLGDAYVEVSENSESWEPSAPEASAEPFDTQSPQAGPQLETD", "length": 944, "header": "tr|E1BGF9-1|E1BGF9_BOVIN Isoform 1 of Zinc fingers and homeoboxes protein 3 OS=Bos taurus OX=9913 GN=ZHX3 PE=3 SV=3 CANONICAL=E1BGF9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NPU6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGF9/entry#A0ABI0NPU6-1", "sequence": { "sequence": "MASKRKSTTPCMIPVKTVVLPGSSAEAPPAEPGPEGPPQEPPPEAPATSTEATQGASGPDVPSLANGHRGTLDGYAYACKYCDFRSQDITQFVGHLSSEHTDFNKDPSFVCTECSFLAKTPEGLSLHNAKCHSGEANFVWNVTKPDNHVVVEQSVPEGGSPPDLSGEPNVEGMDGQAEIIITKTPIMKIMKGKAEAKKIHTLKENVPNQPTGDALPNPPAGDTEVKEGDHASVNGAAPSSQASTNPAKPPHSANGPLLGTVPVLPAGIAQLLSLQQPPPQAQQPLPTARSLPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASSGNVQHLIQAALPGHVVGQPEGTAGGLLVTQPLMANGLQAPSSALPLAVTSVPKPPAVAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDASIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSAREVRKWFSDRRYHCRNLKGARAALSGEHGSLLVDPVPEAPFSPPCKAPEVTCLPTAATLATPPSAKRQSWHQTPDFTPTKYKERAPEQLRALESSFAQNPLPLDEELDRLRTETKMTRREIDGWFSERRKKVSAEEAKKAEEGASPGEEEAAETEGEEGLAGENGSPEVPGGHTLAERKVSPIKINLKNLRVTEANGRGELVGLGICEPEDEAPGKLAEQPPGKAGCKKTAQQRHLLRQLFVQTQWPSTQDYGSIVAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPSNRELLQDYYVTHKMLYEQDLQSLCDKTQMSAQQVKQWFAEKLGEETRAVADTGSEGQGPCAGDPAALHKGLGDAYVEVSENSESWEPSAPEASAEPFDTQSPQAGPQLGKEPPRTVPSSEDAGALGGGELSLGPG", "length": 968, "header": "tr|A0ABI0NPU6-1|A0ABI0NPU6_BOVIN Computationally mapped isoform of Zinc fingers and homeoboxes protein 3 OS=Bos taurus OX=9913 GN=ZHX3 PE=3 SV=1 CANONICAL=E1BGF9-1" }, "locus": { "chromosome": "13", "start_pos": 69837988, "end_pos": 69835085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137224.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137224.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104035.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104035.1" } ] } }, { "isoform_ac": "E1BGF9-1", "url": "https://www.uniprot.org/uniprotkb/E1BGF9/entry#E1BGF9-1", "sequence": { "sequence": "MASKRKSTTPCMIPVKTVVLPGSSAEAPPAEPGPEGPPQEPPPEAPATSTEATQGASGPDVPSLANGHRGTLDGYAYACKYCDFRSQDITQFVGHLSSEHTDFNKDPSFVCTECSFLAKTPEGLSLHNAKCHSGEANFVWNVTKPDNHVVVEQSVPEGGSPPDLSGEPNVEGMDGQAEIIITKTPIMKIMKGKAEAKKIHTLKENVPNQPTGDALPNPPAGDTEVKEGDHASVNGAAPSSQASTNPAKPPHSANGPLLGTVPVLPAGIAQLLSLQQPPPQAQQPLPTARSLPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASSGNVQHLIQAALPGHVVGQPEGTAGGLLVTQPLMANGLQAPSSALPLAVTSVPKPPAVAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDASIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSAREVRKWFSDRRYHCRNLKGARAALSGEHGSLLVDPVPEAPFSPPCKAPEVTCLPTAATLATPPSAKRQSWHQTPDFTPTKYKERAPEQLRALESSFAQNPLPLDEELDRLRTETKMTRREIDGWFSERRKKVSAEEAKKAEEGASPGEEEAAETEGEEGLAGENGSPEVPGGHTLAERKVSPIKINLKNLRVTEANGRGELVGLGICEPEDEAPGKLAEQPPGKAGCKKTAQQRHLLRQLFVQTQWPSTQDYGSIVAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPSNRELLQDYYVTHKMLYEQDLQSLCDKTQMSAQQVKQWFAEKLGEETRAVADTGSEGQGPCAGDPAALHKGLGDAYVEVSENSESWEPSAPEASAEPFDTQSPQAGPQLETD", "length": 944, "header": "tr|E1BGF9-1|E1BGF9_BOVIN Isoform 1 of Zinc fingers and homeoboxes protein 3 OS=Bos taurus OX=9913 GN=ZHX3 PE=3 SV=3 CANONICAL=E1BGF9-1" }, "locus": { "chromosome": "13", "start_pos": 69837988, "end_pos": 69832960, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023393.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023393.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023393.6", "url": "https://www.ensembl.org/id/ENSBTAP00000023393.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512451", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512451", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BCP2-1", "protein_name": "Zinc fingers and homeoboxes protein 3", "gene_name": "ZHX3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASKRKSTTPCMIPVKTVVLQDASTEAPPAEAVPEGPPQEPAPEAPATGSEAAQGASSPDGATLANGHRSALDGYSFACKYCDFRSQDITQFVGHLNSEHTDFNKDPTFVCTECSFLAKTPEGLSLHNAKCHSGEASFVWNVAKPDNHAIVEQSLPENSSPPDPLGEPSVEGTDGQAEIIITKTPIMKIMKGKAEAKKIHTLKENVPSQPTGEASSNPSAGDTEVKEGDQAFVNGAAPVSQASTNSAKPPHVANGPLLGTVPVLPAGIAQFLSLQQPAPHTQHHAHQPLPTAKSLPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASAGNVQHLIQAALPGHVVGQPEGTAGGLLVTQPLMANGLQAPSSSLPLAVTSVPKPPSVAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDASIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRRYHCRNLKGSRAGLPGEHGSLLVDSGPEVAFSPSSKAPEVTCVPTAATLATPPSAKRQSWHQTPDFTPTKYKERAPEQLRALESSFAQNPLPLDEELDRLRTETKMTRREIDGWFSERRKKVSAEEAKKAEEGASQGEEEAAEEQGEEGSAGDLKVPGESGSPEVLGSHSLAERKVSPIKINLKNLRVTEANGKSELLGLGTCEPEDDVPSKLAEQPSGKVSCKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPNNRELLQDYYVTHKMLYEADLQGLCDKTQMSAQQVKQWFAEKMGEETRAVADTASESQGPGAGDPAMVHRGMGDTYLEVSENSESWEPGAPEASSEPFDTPSPQAGPQLETD", "length": 954 }, "evidence": [ { "id": "E1BGF9", "url": "https://omabrowser.org/oma/group/E1BGF9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZHR8-1", "protein_name": "Zinc fingers and homeoboxes protein 3", "gene_name": "ZHX3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASKRKSTTPCMIPVKTLVLQETELETVEEEPEGTQQDAPTEGLAPSNAGATTSSSEALSNGYRSITDGDTYICKGCDFGSQDVQHFFGHLDSEHSDFSKEPTFVCVACNFLVKSHEGLSQHNTESHGSETSFVWRVAKQDGRTVVEQSLSDTASSHNPAGEVPEEAVDGQSEIIITKTPIMKIMKGKPEAKKIHTLKENVPSQLGAESETKDGEASFTSGTAPVSQATASATKSSHVVNGSIIGNVPVLPAGVAQLVSLQQQQPPLHQQLPTSKSLPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVANPGSVPHLIQATLPGHVVGQPEGTGGLLVTQPIMANGLKGTSSSFTLAVSSVPKPPPAAQHSTVSSGSASALKVVTATPSVLTACPAISSQTFLDPNVFKNKKSHEQLSALKGSFCRNQFPGQAEVERLTKITGLSTKEIRKWFSDRRYHYRNVRGGRAVFPGDSALDSLPEIPLEVPPKGAELTPAAAAAPVLQHPGRRQSWHQAPDFTATKYKERAPEQLKALENSFAQNPQPPEEEVNRLRGETKMTRREIDSWFTERRKKKVAEESKKAEEAGQQQEEEEAENGRGEGEDSLDDLRALGENGSLDASAGNPNSAERKVSPIKINLKNLRVTESNGKGEAPGTTAGEKGDGGSNQPPSPPKPKLNFKKTAQQRHLLKQMFVQTQRPTNQEYDAIVSQTGLPRAEVIRWFGDSRYGYKNGQLKWYENYRRGIFPPGLLEVSAAGREVLEEHYKKHKALREDDVPGLCERTQLSAQQVKVWFAAKVEEETRSSSEDAFSSSEQTGSQKGPPDAGSEVSENSEPWEPGGPEGAAEPPGAPVQPPATQLGKGLRAGGCVLGTLLPTGS", "length": 945 }, "evidence": [ { "id": "E1BGF9", "url": "https://omabrowser.org/oma/group/E1BGF9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q80Z36-1", "protein_name": "Zinc fingers and homeoboxes protein 3", "gene_name": "Zhx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKRKSTTPCMIPVKTMVLPGASTEAQPVEPLPEGPQQDLPSEAPEASSEAAPNPSSTDGSALANGHRGTLDGYVYSCKECDFRSQDVTHFVGHMTSEHTDFNKDPHFVCTGCSFLAKTPEGLSLHNAKCHSGEASFLWNVTKPDNHVVVEQSVPENASSSVLAGESTEGTEIIITKTPIMKIMKGKAEAKKIHMLKENAPTQPGGEALPKPLAGETEGKEGDHTFINGATPVSQASANSTKPPHTANGPLIGTVPVLPAGIAQFLSLQQPTVHPQHHPHQPLPTSKALPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASAGNVQHLIQAALPGHAVGQPEGTAGGLLVTQPLMANGLQASSSSLPLTTASVPKPTAAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDANIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRRYHCRNLKGTRAMVPGEHGSVLIDSVPEVPFPLSSKVPEVPCVPTATSLVSHPATKRQSWHQTPDFTPTKYKERAPEQLRVLESSFAQNPLPPEEELDRLRSETKMTRREIDGWFSERRKRVNAEETKKADGHAPQEEAEGAEEEGRDEELASELRAPGENGSSEMFLSHTLAERKVSPIKINLKNLRVTEASGKSELPGMGMGVCEPEEDGLNKAVEQPPSRVSYKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPGNRELLQDYYMTHKMLCEEDLQTLCEKTQMSAQQVKQWFAEKMGEETRAVADTSSEDQGPGHGEPVAVDKVLGDACAALSENSEAWEPSAPEAGSEPFDTSSPQSGRQLETD", "length": 951 }, "evidence": [ { "id": "E1BGF9", "url": "https://omabrowser.org/oma/group/E1BGF9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C0Q2-1", "protein_name": "Zinc fingers and homeoboxes protein 3", "gene_name": "Zhx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKRKSTTPCMIPVKTVVLPGASTEPQPVESLPEGPQQDLPSEAPDASSEAAPNPSSTDGSALANGHRSTLDGYVYCCKECEFRSQDVTHFIGHMNSEHTDFNKDPTFVCTGCSFLAKNPEGLSLHNAKCHSGEASFLWNVTKPDNHVVVEQSVPDSASSSVLAGESTTEGTEIIITKTPIMKIMKGKAEAKKIHMLKENAPNQPGSEALPKPLAGEREVKEGDHTFINGAAPGSQASAKSTKPPPAANGPLIGTVPVLPAGIAQFLSLQQQPPVHAQHHTHQPLPTSKTLPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASAGNVQHLIQATLPGHAVGQPEGTAGGLLVTQPLMANGLQASSSSLPLTTASVPKPTVAPINTVCSNSASAVKVVNAAQSLLTACPSITSQAFLDANIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRRYHCRNLKGSRAMMPGEHGSVLIDSVPEVPFPLASKVPEVTCIPTATSLVSHPATKRQSWHQTPDFTPTKYKERAPEQLRVLENSFAQNPLPPEEELDRLRSETKMTRREIDGWFSERRKKVNTEETKKADGHMPKEEEEGAEQEGRDEELANELRVPGENGSPEMFLSHALAERKVSPIKINLKNLRVTEASGKSEFPGMGVCEPEEDGLNKLVEQPPSKVSYKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPGNRELLQDYYMTHKMLCEEDLQTLCDKTQMSAQQVKQWFAEKMGEETRAVADISSEDQGPRNGEPVAVHKVLGDAYSELSENSESWEPSAPEASSEPFDTSSPQSGRQLEAD", "length": 951 }, "evidence": [ { "id": "E1BGF9", "url": "https://omabrowser.org/oma/group/E1BGF9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H4I2-1", "protein_name": "Zinc fingers and homeoboxes protein 3", "gene_name": "ZHX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASKRKSTTPCMIPVKTVVLQDASMEAQPAETLPEGPQQDLPPEASAASSEAAQNPSSTDGSTLANGHRSTLDGYLYSCKYCDFRSHDMTQFVGHMNSEHTDFNKDPTFVCSGCSFLAKTPEGLSLHNATCHSGEASFVWNVAKPDNHVVVEQSIPESTSTPDLAGEPSAEGADGQAEIIITKTPIMKIMKGKAEAKKIHTLKENVPSQPVGEALPKLSTGEMEVREGDHSFINGAVPVSQASASSAKNPHAANGPLIGTVPVLPAGIAQFLSLQQQPPVHAQHHVHQPLPTAKALPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASAGNVQHLIQAALPGHVVGQPEGTGGGLLVTQPLMANGLQATSSPLPLTVTSVPKQPGVAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDASIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRRYHCRNLKGSRAMIPGDHSSIIIDSVPEVSFSPSSKVPEVTCIPTTATLATHPSAKRQSWHQTPDFTPTKYKERAPEQLRALESSFAQNPLPLDEELDRLRSETKMTRREIDSWFSERRKKVNAEETKKAEENASQEEEEAAEDEGGEEDLASELRVSGENGSLEMPSSHILAERKVSPIKINLKNLRVTEANGRNEIPGLGACDPEDDESNKLAEQLPGKVSCKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPGNRELLQDYYMTHKMLYEEDLQNLCDKTQMSSQQVKQWFAEKMGEETRAVADTGSEDQGPGTGELTAVHKGMGDTYSEVSENSESWEPRVPEASSEPFDTSSPQAGRQLETD", "length": 956 }, "evidence": [ { "id": "E1BGF9", "url": "https://omabrowser.org/oma/group/E1BGF9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BGF9", "url": "https://www.uniprot.org/uniprotkb/E1BGF9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BGF9", "url": "https://www.uniprot.org/uniprotkb/E1BGF9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BGF9", "url": "https://www.uniprot.org/uniprotkb/E1BGF9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BGF9", "url": "https://www.uniprot.org/uniprotkb/E1BGF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BGF9", "url": "https://www.uniprot.org/uniprotkb/E1BGF9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BGF9", "url": "https://www.uniprot.org/uniprotkb/E1BGF9" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BGF9", "url": "https://www.uniprot.org/uniprotkb/E1BGF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 694, "end_pos": 696, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGF9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 944, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGF9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGF9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGF9" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 314, "end_pos": 357, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 694, "end_pos": 696 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGG7-1", "uniprot_ac": "E1BGG7", "uniprot_id": "E1BGG7_BOVIN", "mass": { "chemical_mass": 71026.0, "monoisotopic_mass": 71026.0 }, "refseq": {}, "gene_names": [ { "name": "SLC24A3", "type": "recommended", "evidence": [ { "id": "E1BGG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGG7" } ] } ], "protein_names": [ { "name": "Solute carrier family 24 member 3", "type": "synonym", "evidence": [ { "id": "E1BGG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGG7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGG7", "url": "https://www.uniprot.org/uniprotkb/E1BGG7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC24A3", "url": "https://www.uniprot.org/uniprotkb/E1BGG7", "locus": { "chromosome": "13", "start_pos": 39336211, "end_pos": 38890847, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011882", "url": "https://www.ensembl.org/id/ENSBTAG00000011882" } ] } } ], "crossref": [ { "id": "E1BGG7", "url": "https://alphafold.ebi.ac.uk/entry/E1BGG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011882", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011882", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004481", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004481", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10846", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10846", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10846:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10846:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-425561", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-425561", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "69967", "url": "https://www.rhea-db.org/rhea/69967", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BGG7", "url": "https://www.uniprot.org/uniprotkb/E1BGG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGG7-1", "url": "https://www.uniprot.org/uniprotkb/E1BGG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSPDLEERERRRSCRRDLLLSQVCFLALVALLLWSLSSMRDHDDLNFMDFIGQDTQWTVGRKLMQVNDSLTSEDAGPRSSKNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAMYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVVALIVFIYDEQVSWWESLVLVLMYLIYIVIMKYNACIHQCFERKTKGAGNMVNGLANNAEMDDSGNCDATVVPNFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYANGESEVAIKIPIKHTVENGTGPSSAPDRGVSGTRRDEVVEAGDETENENEDNENNENDEEEEDEEEEEGPYTPFDPPSGKLETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRLIYSVGLLLASVFVTVFGVHLNKWQLDRKLGCGCLFLYGVFLCFSIMTEFNVFTFVNLPMCGDH", "length": 637, "header": "tr|E1BGG7-1|E1BGG7_BOVIN Isoform 1 of Solute carrier family 24 member 3 OS=Bos taurus OX=9913 GN=SLC24A3 PE=3 SV=4 CANONICAL=E1BGG7-1" }, "isoforms": [ { "isoform_ac": "E1BGG7-1", "url": "https://www.uniprot.org/uniprotkb/E1BGG7/entry#E1BGG7-1", "sequence": { "sequence": "MPSPDLEERERRRSCRRDLLLSQVCFLALVALLLWSLSSMRDHDDLNFMDFIGQDTQWTVGRKLMQVNDSLTSEDAGPRSSKNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAMYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVVALIVFIYDEQVSWWESLVLVLMYLIYIVIMKYNACIHQCFERKTKGAGNMVNGLANNAEMDDSGNCDATVVPNFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYANGESEVAIKIPIKHTVENGTGPSSAPDRGVSGTRRDEVVEAGDETENENEDNENNENDEEEEDEEEEEGPYTPFDPPSGKLETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRLIYSVGLLLASVFVTVFGVHLNKWQLDRKLGCGCLFLYGVFLCFSIMTEFNVFTFVNLPMCGDH", "length": 637, "header": "tr|E1BGG7-1|E1BGG7_BOVIN Isoform 1 of Solute carrier family 24 member 3 OS=Bos taurus OX=9913 GN=SLC24A3 PE=3 SV=4 CANONICAL=E1BGG7-1" }, "locus": { "chromosome": "13", "start_pos": 39335207, "end_pos": 38891367, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015768.8", "url": "https://www.ensembl.org/id/ENSBTAT00000015768.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015768.8", "url": "https://www.ensembl.org/id/ENSBTAP00000015768.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-425561", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-425561", "resource": "Reactome", "description": "Sodium/Calcium exchangers" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "E1BGG7", "url": "https://www.uniprot.org/uniprotkb/E1BGG7" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "E1BGG7", "url": "https://www.uniprot.org/uniprotkb/E1BGG7" } ], "pmid": "" }, { "name": "calcium, potassium:sodium antiporter activity", "id": "GO:0008273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008273", "evidence": [ { "database": "UniProtKB", "id": "E1BGG7", "url": "https://www.uniprot.org/uniprotkb/E1BGG7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BGG7", "url": "https://www.uniprot.org/uniprotkb/E1BGG7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "E1BGG7", "url": "https://www.uniprot.org/uniprotkb/E1BGG7" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "E1BGG7", "url": "https://www.uniprot.org/uniprotkb/E1BGG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "69967", "name": "", "equation": "Ca(2+)(out) + K(+)(out) + 4 Na(+)(in) = Ca(2+)(in) + K(+)(in) + 4 Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "69967", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69967" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGG7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 637, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGG7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGG7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGG7" }, { "id": "PF01699", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01699" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sodium/calcium exchanger membrane region", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 252, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 376, "end_pos": 378 }, { "start_pos": 68, "end_pos": 70 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGH1-1", "uniprot_ac": "E1BGH1", "uniprot_id": "E1BGH1_BOVIN", "mass": { "chemical_mass": 57897.0, "monoisotopic_mass": 57897.0 }, "refseq": { "ac": "XP_005223573", "name": "UNC5C-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223573" }, "gene_names": [ { "name": "UNC5CL", "type": "recommended", "evidence": [ { "id": "E1BGH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH1" } ] }, { "name": "UNC5CL", "type": "synonym", "evidence": [ { "id": "XP_005223573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223573" } ] } ], "protein_names": [ { "name": "UNC5C-like protein", "type": "recommended", "evidence": [ { "id": "E1BGH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH1/entry#names_and_taxonomy" } ] }, { "name": "Protein unc-5 homolog C-like", "type": "synonym", "evidence": [ { "id": "E1BGH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH1/entry#names_and_taxonomy" } ] }, { "name": "UNC5C-like protein", "type": "synonym", "evidence": [ { "id": "XP_005223573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223573" } ] }, { "name": "ZU5 and death domain-containing protein", "type": "synonym", "evidence": [ { "id": "E1BGH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Inhibits NF-kappa-B-dependent transcription by impairing NF-kappa-B binding to its targets.", "evidence": [ { "database": "UniProtKB", "id": "E1BGH1", "url": "https://www.uniprot.org/uniprotkb/E1BGH1#function" }, { "database": "UniProtKB", "id": "ARBA00057851", "url": "https://www.uniprot.org/uniprotkb/ARBA00057851#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGH1", "url": "https://www.uniprot.org/uniprotkb/E1BGH1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UNC5CL", "url": "https://www.uniprot.org/uniprotkb/E1BGH1", "locus": { "chromosome": "23", "start_pos": 14950492, "end_pos": 14967514, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002919", "url": "https://www.ensembl.org/id/ENSBTAG00000002919" } ] } } ], "crossref": [ { "id": "E1BGH1", "url": "https://alphafold.ebi.ac.uk/entry/E1BGH1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002919", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002919", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "615134", "url": "https://www.ncbi.nlm.nih.gov/gene/615134", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:615134", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615134", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VTRQLMH", "url": "https://omabrowser.org/oma/group/VTRQLMH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGH1", "url": "https://www.orthodb.org/?gene=E1BGH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12582", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12582", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12582:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12582:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005223573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BGH1", "url": "https://www.uniprot.org/uniprotkb/E1BGH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGH1-1", "url": "https://www.uniprot.org/uniprotkb/E1BGH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSYESSFQPAQFLLLVGVPLASAVLLVQCLRWRCPRRLLGSCWKLESQEEPAPPPTPLPEDESSRAGLPATLQEVATFYQELHTPTQGQTVIRQLMHKLLVFSAREVDHRGGCLMLQDTGISLLIPPGAVSMGRQERVSLTLVWDLTDAPSLSRAQGLVSPVVACGPHGASFLKPCTLTFKHCAQQPSQARAYSSNTALLDTKAWKPLGRPGDHTSRDECRIHLSHFSLYTCVLEAPVGREARKWLQLALFCSPLAPGQSHLQLRVYFLNNTPCALQWAVTNEQPHGGRLRGPCQLFDFTGARGDQCLKLKYISEGWENVDDSSCQLVPHLHIWHGKCPFRSFCFRRKAAKDNEDCSALTNEIIVTMHTFQDGLETKYMEILRFQASEEESWTAPPPVTQPPACNRLPPELFEQLQMLLEPNSITGNDWRRLASHLGLCGMKIRFMSCQRSPAAAILELFEEQNGSLQELHYLMTLMERLDCASVIQNYLNGTQSGSPPRLRAGAQENQGLELDEKL", "length": 518, "header": "tr|E1BGH1-1|E1BGH1_BOVIN Isoform 1 of UNC5C-like protein OS=Bos taurus OX=9913 GN=UNC5CL PE=3 SV=1 CANONICAL=E1BGH1-1" }, "isoforms": [ { "isoform_ac": "E1BGH1-1", "url": "https://www.uniprot.org/uniprotkb/E1BGH1/entry#E1BGH1-1", "sequence": { "sequence": "MCSYESSFQPAQFLLLVGVPLASAVLLVQCLRWRCPRRLLGSCWKLESQEEPAPPPTPLPEDESSRAGLPATLQEVATFYQELHTPTQGQTVIRQLMHKLLVFSAREVDHRGGCLMLQDTGISLLIPPGAVSMGRQERVSLTLVWDLTDAPSLSRAQGLVSPVVACGPHGASFLKPCTLTFKHCAQQPSQARAYSSNTALLDTKAWKPLGRPGDHTSRDECRIHLSHFSLYTCVLEAPVGREARKWLQLALFCSPLAPGQSHLQLRVYFLNNTPCALQWAVTNEQPHGGRLRGPCQLFDFTGARGDQCLKLKYISEGWENVDDSSCQLVPHLHIWHGKCPFRSFCFRRKAAKDNEDCSALTNEIIVTMHTFQDGLETKYMEILRFQASEEESWTAPPPVTQPPACNRLPPELFEQLQMLLEPNSITGNDWRRLASHLGLCGMKIRFMSCQRSPAAAILELFEEQNGSLQELHYLMTLMERLDCASVIQNYLNGTQSGSPPRLRAGAQENQGLELDEKL", "length": 518, "header": "tr|E1BGH1-1|E1BGH1_BOVIN Isoform 1 of UNC5C-like protein OS=Bos taurus OX=9913 GN=UNC5CL PE=3 SV=1 CANONICAL=E1BGH1-1" }, "locus": { "chromosome": "23", "start_pos": 14958249, "end_pos": 14951496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003791.6", "url": "https://www.ensembl.org/id/ENSBTAT00000003791.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003791.3", "url": "https://www.ensembl.org/id/ENSBTAP00000003791.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:615134", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615134", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MKD8-1", "protein_name": "Unc-5 family C-terminal like", "gene_name": "Unc5cl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPQESSVQPFQFLLLVGIPVASVLLLVQCLRWHRCRWPPGSCQKPDDPEEPVSPSTPLPEYELPKQCQAPTLPEVAAFYQELHMPTRGQTITRQLMNKLLVFSAREVDHRGGCLMLQDTGISLLIPPGAVTVGRQERVSLVLVWDLTDAPSLSHKQGLVSPVVACGPHGASFLKPCILTFKHCAQQPSQVCAYSSNTSLLDAKDWRPLGQPGTHTSRDECRILLSHFSLYTCVLEPPLGQTARKWLQLAMFCSPLAPGQTHLQLRVYFLNNTPCALQWAITNEQPHGGRMRGPCQLFDFTGARADQCLKLKYISEGWENVDDSSSQLVPHLHIWHGKCPFRSFCFRRKSANGNEECSTLTNEIIVTMHTFQDGLETKYMEILRFQASEEETWAVPPPVSQPPLCNRLPPELFEQLQMLLEPSSVTGNDWRKLASHLGLCGMKIRFLSCQRSPAAAILELFEEQNGSLQELHYLMTSMERLDCASAIQNYLNRTPGDSPTRLRGGTWENCGLELDEKF", "length": 518 }, "evidence": [ { "id": "E1BGH1", "url": "https://omabrowser.org/oma/group/E1BGH1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LUA4-1", "protein_name": "UNC5C-like protein", "gene_name": "UNC5CL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCAHESSFQPAQFLLLVGVPVASAVLLVQCLRWRCPRRLLGACWKLESQEEPASIHPAPLPENESPGQGPPATLQEMVSFYQELHTPTQGQTIIRQLMHKLLMFSAREVDHRGGCLMLQDAGISLLIPPGAVSVGRQERVSLVLVWDLSDAPSLSRAQGLVSPVVACGPHGASFLKPCTLTFKHCAQQPSHARTYSSNTTLLDAKAWKPLGRRGDHTSRDECRIQLSHFSLYTCVLEAPAGQEARKWLQLAVFCSPLAPGQTHLQLRVYFLNNTPCALQWAVTNEQPHGGRLRGPCQLFDFTGARGDQCLKLKYISEGWENVDDSSCQLVPHLHIWHGKCPFRSFCFRRKAANENEDCSALTNEIIVTMHTFQDGLETKYMEILRFQASEEESWAAPPPVTQPPPCNRLPPELFERLQMLLEPNSITGNDWRRLASHLGLCGMKIRFLSCQRSPAAAILELFEEQNGSLQELHYLMTIMERLDCASVIQNYLNGTQSGSPALVRGGAQENQALELDEKL", "length": 519 }, "evidence": [ { "id": "E1BGH1", "url": "https://omabrowser.org/oma/group/E1BGH1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6R653-1", "protein_name": "UNC5C-like protein", "gene_name": "Unc5cl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPQESSVQPSQFLLLVGIPVASALLLAQCLRWHCCQWLPGTCRKPDDPEEPVSPSTPLPEYELPRQCPAPTLPEVAAFYQELHMPTQGQTVTRQMMHKLLVFSAREVDHRGGCLILQDTGISLLIPPGAVTVGRQERVSLVLVWDLTDAPSLSHRQGLVSPVVACGPHGASFLKPCTLTFKHCAQQPSQACAYSSNTSLLDAKDWKPLGQPGTHISRDECRILLSHFSLYTCVLEAPLGQTARKWLQLAMFCSPLVPGQTHLQLRVYFLNNTPCALQWAITNEQPHGGRMRGPCQLFDFTGARADQCLKLKYISEGWENVDDSSSQLVPHLHIWHGKCPFRSFCFRRKAANGNEECSALTNEIIVTMHTFQDGLETKYVEILRFQASEEETWAVPPPVSQPPLCNRLPPELFEQLQMLLEPNSVTGNDWRRLASHLGLCGMKIRFLSCQRSPAAAILELFEEQNGSLQELHYLMTSMERLDCASAIQNYLNRSPRGSPDRLHGGTWENHGLELDEKL", "length": 518 }, "evidence": [ { "id": "E1BGH1", "url": "https://omabrowser.org/oma/group/E1BGH1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IV45-1", "protein_name": "UNC5C-like protein", "gene_name": "UNC5CL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCPQESSFQPSQFLLLVGVPVASVLLLAQCLRWHCPRRLLGACWTLNGQEEPVSQPTPQLENEVSRQHLPATLPEMVAFYQELHTPTQGQTMVRQLMHKLLVFSAREVDHRGGCLMLQDTGISLLIPPGAVAVGRQERVSLILVWDLSDAPSLSQAQGLVSPVVACGPHGASFLKPCTLTFKHCAEQPSHARTYSSNTTLLDAKVWRPLGRPGAHASRDECRIHLSHFSLYTCVLEAPVGREARKWLQLAVFCSPLVPGQSHLQLRIYFLNNTPCALQWALTNEQPHGGRLRGPCQLFDFNGARGDQCLKLTYISEGWENVDDSSCQLVPHLHIWHGKCPFRSFCFRRKAADENEDCSALTNEIIVTMHTFQDGLETKYMEILRFQASEEESWAAPPPVSQPPPCNRLPPELFEQLRMLLEPNSITGNDWRRLASHLGLCGMKIRFLSCQRSPAAAILELFEEQNGSLQELHYLMTVMERLDCASAIQNYLSGTHGGSPGPERGGARDNQGLELDEKL", "length": 518 }, "evidence": [ { "id": "E1BGH1", "url": "https://omabrowser.org/oma/group/E1BGH1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BGH1", "url": "https://www.uniprot.org/uniprotkb/E1BGH1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BGH1", "url": "https://www.uniprot.org/uniprotkb/E1BGH1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "E1BGH1", "url": "https://www.uniprot.org/uniprotkb/E1BGH1" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "E1BGH1", "url": "https://www.uniprot.org/uniprotkb/E1BGH1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "E1BGH1", "url": "https://www.uniprot.org/uniprotkb/E1BGH1" } ], "pmid": "" }, { "name": "netrin receptor activity", "id": "GO:0005042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005042", "evidence": [ { "database": "UniProtKB", "id": "E1BGH1", "url": "https://www.uniprot.org/uniprotkb/E1BGH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGH1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 518, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGH1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGH1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH1" }, { "id": "PS50017", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Death", "eco_id": "ECO_0000259", "start_pos": 415, "end_pos": 494, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BGH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH1" }, { "id": "PS51145", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZU5", "eco_id": "ECO_0000259", "start_pos": 102, "end_pos": 237, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 57 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 492, "end_pos": 494 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGH7-1", "uniprot_ac": "E1BGH7", "uniprot_id": "E1BGH7_BOVIN", "mass": { "chemical_mass": 45998.0, "monoisotopic_mass": 45998.0 }, "refseq": { "ac": "XP_024843418", "name": "potassium channel subfamily K member 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024843418" }, "gene_names": [ { "name": "KCNK4", "type": "recommended", "evidence": [ { "id": "E1BGH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH7" } ] }, { "name": "KCNK4", "type": "synonym", "evidence": [ { "id": "XP_024843418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024843418" } ] } ], "protein_names": [ { "name": "Potassium channel subfamily K member 4", "type": "recommended", "evidence": [ { "id": "E1BGH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH7/entry#names_and_taxonomy" } ] }, { "name": "TWIK-related arachidonic acid-stimulated potassium channel protein", "type": "synonym", "evidence": [ { "id": "E1BGH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGH7/entry#names_and_taxonomy" } ] }, { "name": "potassium channel subfamily K member 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024843418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024843418" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGH7", "url": "https://www.uniprot.org/uniprotkb/E1BGH7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KCNK4", "url": "https://www.uniprot.org/uniprotkb/E1BGH7", "locus": { "chromosome": "29", "start_pos": 42599230, "end_pos": 42592034, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008644", "url": "https://www.ensembl.org/id/ENSBTAG00000008644" } ] } } ], "crossref": [ { "id": "E1BGH7", "url": "https://alphafold.ebi.ac.uk/entry/E1BGH7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008644", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008644", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617184", "url": "https://www.ncbi.nlm.nih.gov/gene/617184", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BGH7", "url": "https://www.orthodb.org/?gene=E1BGH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1299503", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1299503", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024843418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024843418", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78547", "url": "https://www.rhea-db.org/rhea/78547", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78555", "url": "https://www.rhea-db.org/rhea/78555", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BGH7", "url": "https://www.uniprot.org/uniprotkb/E1BGH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGH7-1", "url": "https://www.uniprot.org/uniprotkb/E1BGH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAAPQEPPAQPPQAGSGVGRAPGRAMRSTTLLALLALVLLYLVSGALVFQALEQPHEQQAQRELGEVREKFLRAHPCVSDQDLGLFIKDVADALGGGANPDTNSTSNSNHSAWDLGSAFFFSGTIITTIGYGNAALRTDAGRLFCIFYALVGIPLFGILLAGVGDRLGSSLRRGIGHIEAIFLKWHVPPGLVRILSAVLFLLIGCLLFVLTPTFVFCYMEGWSKLEAIYFVVVTLTTVGFGDYVAGASPNQNFAAYQPLVWFWILLGLAYFASVLTTIGNWLRVVSRRTRAEMGGLTAQAASWTGTVTARVTQRVGPTAPPPLEKERPPLPPPPCTAQPASRPLSPAAPEKTEPSSPPSPPTPPTPPTASALDYPSENLAFIDESSDTQSERGCALPRAPRGRRRPLNPPRKPSRPRGPGRPRDKGVPA", "length": 430, "header": "tr|E1BGH7-1|E1BGH7_BOVIN Isoform 1 of Potassium channel subfamily K member 4 OS=Bos taurus OX=9913 GN=KCNK4 PE=3 SV=5 CANONICAL=E1BGH7-1" }, "isoforms": [ { "isoform_ac": "E1BGH7-1", "url": "https://www.uniprot.org/uniprotkb/E1BGH7/entry#E1BGH7-1", "sequence": { "sequence": "MTAAPQEPPAQPPQAGSGVGRAPGRAMRSTTLLALLALVLLYLVSGALVFQALEQPHEQQAQRELGEVREKFLRAHPCVSDQDLGLFIKDVADALGGGANPDTNSTSNSNHSAWDLGSAFFFSGTIITTIGYGNAALRTDAGRLFCIFYALVGIPLFGILLAGVGDRLGSSLRRGIGHIEAIFLKWHVPPGLVRILSAVLFLLIGCLLFVLTPTFVFCYMEGWSKLEAIYFVVVTLTTVGFGDYVAGASPNQNFAAYQPLVWFWILLGLAYFASVLTTIGNWLRVVSRRTRAEMGGLTAQAASWTGTVTARVTQRVGPTAPPPLEKERPPLPPPPCTAQPASRPLSPAAPEKTEPSSPPSPPTPPTPPTASALDYPSENLAFIDESSDTQSERGCALPRAPRGRRRPLNPPRKPSRPRGPGRPRDKGVPA", "length": 430, "header": "tr|E1BGH7-1|E1BGH7_BOVIN Isoform 1 of Potassium channel subfamily K member 4 OS=Bos taurus OX=9913 GN=KCNK4 PE=3 SV=5 CANONICAL=E1BGH7-1" }, "locus": { "chromosome": "29", "start_pos": 42599227, "end_pos": 42592034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011399.8", "url": "https://www.ensembl.org/id/ENSBTAT00000011399.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011399.8", "url": "https://www.ensembl.org/id/ENSBTAP00000011399.8" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 319, "start_aa": "Thr", "end_pos": 319, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr319", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 363, "start_aa": "Thr", "end_pos": 363, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr363", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { 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[ { "id": "E1BGJ3", "url": "https://omabrowser.org/oma/group/E1BGJ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5NCD7-1", "protein_name": "Olfactory receptor", "gene_name": "Or2ak5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESGNHSCGTEFTLVGLFQYGHMDTFLFTLIAILFAVALMGNITLVLLIRLDRRLHTPMYFFLSQLSIIDMMYISTTVPKMAANFLSDTKAISFLGCAVQTFVFLTLGGSEALLLGFMSYDRYIAICQPLHYPVLMSRKICCSMVAGAWSSSSINAFMHTVYVFQLPFCGSRMVNHFFCEVPSLLPLVCEDTSQYEHTVLVSGLVILLLPFLAILASYARVLVVVIQMGSGKGQSRAVSTCSSHLTVASLFYVTTLSTYTQPHSLHSPGRDKVVAVLYSIVTPVLNPFIYSLRNKEVMGALRRQRG", "length": 306 }, "evidence": [ { "id": "E1BGJ3", "url": "https://omabrowser.org/oma/group/E1BGJ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NG84-1", "protein_name": "Olfactory receptor 2AK2", "gene_name": "OR2AK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNISDVISFDILVSAMKTGNQSFGTDFLLVGLFQYGWINSLLFVVIATLFTVALTGNIMLIHLIRLNTRLHTPMYFLLSQLSIVDLMYISTTVPKMAVSFLSQSKTIRFLGCEIQTYVFLALGGTEALLLGFMSYDRYVAICHPLHYPMLMSKKICCLMVACAWASGSINAFIHTLYVFQLPFCRSRLINHFFCEVPALLSLVCQDTSQYEYTVLLSGLIILLLPFLAILASYARVLIVVFQMSSGKGQAKAVSTCSSHLIVASLFYATTLFTYTRPHSLRSPSRDKAVAVFYTIVTPLLNPFIYSLRNKEVTGAVRRLLGYWICCRKYDFRSLY", "length": 335 }, "evidence": [ { "id": "E1BGJ3", "url": "https://omabrowser.org/oma/group/E1BGJ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ3", "url": "https://www.uniprot.org/uniprotkb/E1BGJ3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ3", "url": "https://www.uniprot.org/uniprotkb/E1BGJ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ3", "url": "https://www.uniprot.org/uniprotkb/E1BGJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ3", "url": "https://www.uniprot.org/uniprotkb/E1BGJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGJ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGJ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGJ3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGJ3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGJ5-1", "uniprot_ac": "E1BGJ5", "uniprot_id": "E1BGJ5_BOVIN", "mass": { "chemical_mass": 69355.0, "monoisotopic_mass": 69355.0 }, "refseq": { "ac": "XP_003586832", "name": "complement component C1q receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586832" }, "gene_names": [ { "name": "CD93", "type": "recommended", "evidence": [ { "id": "E1BGJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" } ] }, { "name": "CD93", "type": "synonym", "evidence": [ { "id": "XP_003586832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586832" } ] } ], "protein_names": [ { "name": "CD93 molecule", "type": "synonym", "evidence": [ { "id": "E1BGJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5/entry#names_and_taxonomy" } ] }, { "name": "complement component C1q receptor", "type": "synonym", "evidence": [ { "id": "XP_003586832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586832" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGJ5", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CD93", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5", "locus": { "chromosome": "13", "start_pos": 41878375, "end_pos": 41881424, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004207", "url": "https://www.ensembl.org/id/ENSBTAG00000004207" } ] } } ], "crossref": [ { "id": "E1BGJ5", "url": "https://alphafold.ebi.ac.uk/entry/E1BGJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004207", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004207", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539690", "url": "https://www.ncbi.nlm.nih.gov/gene/539690", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539690", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539690", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YTNWHKE", "url": "https://omabrowser.org/oma/group/YTNWHKE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGJ5", "url": "https://www.orthodb.org/?gene=E1BGJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14789", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14789", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14789:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14789:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003586832", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586832", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BGJ5", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGJ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSAGLLLLLLLLSIQSRAENTTDWEAVVCAGSACYTAHRHKLSAEDAQLHCSKKGGNLATVKSEEEAWHIQGALTQLLLLGPPLQERSKFWIGLQREKGTCSDSSLPLKGFSWLGDGEDSQYNNWYKEVRSTCTHRRCVSLILDLSVPGLASGLSKWVDGPCGHSGFPGMNIEGFVCKFSFKGMCRPLTLGGPGQVNYTTPFQATSSSLQAVPFASMATVACEDGNEGRQHYFLCKEKAPSEFDWDSSGPLCVSPKFGCDFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVSCASRNPCSSNPCGGEATCFPGSLGTDFTCHCPPGYQLDSTQRDCVDVDECRDNPCAQDCVNTPGSFRCECWVGFEPGGPEEGACVDVDECAPGHSPCAQSCTNTEGSFYCSCEEGYELAEEDGTQCLDVDECEVQQGGLCDSLCFNTEGSFRCGCLPGWELDPNGVSCTGGHTSLGPPTGFPLREDTGNGEGKLQSSATVSSRSGDNPEGTSTVVPSNRRLSLPARVPTSLPPSEMLAPSATPGVWMEPSTHYPTATTGHRESAGEDFTAKQSEQGTDGQQLLLFYILGTVVAILLLLALALGLLVCRKRRAKKEEKKQQPQSAADSYAWVPERAESRAMENPYSPTPGTDC", "length": 648, "header": "tr|E1BGJ5-1|E1BGJ5_BOVIN Isoform 1 of CD93 molecule OS=Bos taurus OX=9913 GN=CD93 PE=4 SV=3 CANONICAL=E1BGJ5-1" }, "isoforms": [ { "isoform_ac": "E1BGJ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5/entry#E1BGJ5-1", "sequence": { "sequence": "MASSAGLLLLLLLLSIQSRAENTTDWEAVVCAGSACYTAHRHKLSAEDAQLHCSKKGGNLATVKSEEEAWHIQGALTQLLLLGPPLQERSKFWIGLQREKGTCSDSSLPLKGFSWLGDGEDSQYNNWYKEVRSTCTHRRCVSLILDLSVPGLASGLSKWVDGPCGHSGFPGMNIEGFVCKFSFKGMCRPLTLGGPGQVNYTTPFQATSSSLQAVPFASMATVACEDGNEGRQHYFLCKEKAPSEFDWDSSGPLCVSPKFGCDFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVSCASRNPCSSNPCGGEATCFPGSLGTDFTCHCPPGYQLDSTQRDCVDVDECRDNPCAQDCVNTPGSFRCECWVGFEPGGPEEGACVDVDECAPGHSPCAQSCTNTEGSFYCSCEEGYELAEEDGTQCLDVDECEVQQGGLCDSLCFNTEGSFRCGCLPGWELDPNGVSCTGGHTSLGPPTGFPLREDTGNGEGKLQSSATVSSRSGDNPEGTSTVVPSNRRLSLPARVPTSLPPSEMLAPSATPGVWMEPSTHYPTATTGHRESAGEDFTAKQSEQGTDGQQLLLFYILGTVVAILLLLALALGLLVCRKRRAKKEEKKQQPQSAADSYAWVPERAESRAMENPYSPTPGTDC", "length": 648, "header": "tr|E1BGJ5-1|E1BGJ5_BOVIN Isoform 1 of CD93 molecule OS=Bos taurus OX=9913 GN=CD93 PE=4 SV=3 CANONICAL=E1BGJ5-1" }, "locus": { "chromosome": "13", "start_pos": 41881295, "end_pos": 41879113, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005511.7", "url": "https://www.ensembl.org/id/ENSBTAT00000005511.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051405.3", "url": "https://www.ensembl.org/id/ENSBTAP00000051405.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 538, "start_aa": "Thr", "end_pos": 538, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr538", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 643, "start_aa": "Thr", "end_pos": 643, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr643", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539690", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539690", "resource": "KEGG Pathway" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HEG2-1", "protein_name": "Complement component C1q receptor", "gene_name": "Cd93", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTTSTGLLLLLLLLGQSWAGAAADSEAVVCQGTACYTAHWGKVSFTEAQSSCHENGGNLATVKSEEEARYVQQALAQLLKTKEPLEAKMRKFWIGLQREKGKCTYYDLPLKGFSWVGGGEDTAYSNWYKEGKRSCTSNRCVSLILDLPLPPHPSQLPRWYETSCGTPDGNSIEGFLCKFNFKGMCSPLALGGPGQVTYTTPFQATTSSLEAVPFASAANVVCGDEAESKTYYFLCKEKTAGVFHWGSSGPLCISPKLGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGTCHPVPLSENYTCQCPKGYQLDSSQVHCVDIDECQESPCAQECINTPGSFRCECWVGYQSSGPKEATSCEDVDECAHSPCAHRCINTDGSFYCDCKDGYALSGEDSTQCEDIDECSDSRGSPCDTRCVNSEGSFTCGCQSGWELAPNGVSCIKGSVSLEPSTSSPQKEGKGDRKGNTVPPTDMPSSSRGSENVSKGGYPTGRPSLGSDTPSASVPPEIPVPSEASDVWMELDTHLPMTTGYSKPTHEDSVAAHSDSDTDGQKLLLFYILGTVVAISLLLALALGLLIYRKRRAKKEEIKEKKPQNAADSYSWVPERAESRALENQYSPTPGTDC", "length": 644 }, "evidence": [ { "id": "E1BGJ5", "url": "https://omabrowser.org/oma/group/E1BGJ5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0Z9M8-1", "protein_name": "CD93 molecule", "gene_name": "CD93", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVALLLLLLQLLMLVTAVAGGEDAKVLCADTACYTLHRAELGWSAAQERCQNDGGNLAPAGSRAEAERLEQLLADSMATSAWIGLRLERGHCVQSQEPLRGFSWAASGEPSNYSAWLAEPHVTCLSTRCVALRPAGPHGPLGWVDRPCRATLPAFLCKFSFRGMCGPLRLGGPGQVSYETPFRVSSPTLGAAPFGTLAEVVCEGSVSSTFSVCKGQQEGDDFTWHPPGPICPNTCTHNNGGCQQLCLEEQPGKPSLCACQPNYVLGPDMASCLPEDPCHSNPCQGTCRPQPGGFECICEAGYIVAPDGYRCVDVDECLEGPCKHECHNTAGSFFCSCQPGYQPAGPDGHDCRDEDECAQPNACPQLCLNIAGSFRCLCKAGYQQQPGSDACLDIDECLRNPCPGPCRNLPGSFECICLPGFLPQDDGHGCLTAPTTGEQLAGTMGTTAILQTASTAWTVGTPSPAAIPGGLAPPAPTVVVSEHSPEHGADGPRLLLYYILGSLVAILLLLAFALALLACRKRASRQEKTKAKSAADNYCWVPEQPESRSRAGSERR", "length": 557 }, "evidence": [ { "id": "E1BGJ5", "url": "https://omabrowser.org/oma/group/E1BGJ5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SAT8-1", "protein_name": "CD93 molecule", "gene_name": "CD93", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTTSPGLLLLLLLLLVQPREGATSQEAVVCVGTACYSAHWGKLSADEAQLHCDKKGGNLATLKSEEEARHVQGTLAQLLQPGAPLAERMGRFWIGLQRDKGKCLDSDLPLKGFRWVDGVEDTPYTNWHKEAKNSCISKRCVSLLLDLSTPALASRLSKWAEGPCGSSRSPGNSVEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQATSSTLQAVPFGSMAHVACGDRDESQQPYFLCKEKAPNVFEWNSSGPLCISPKLGCDFNNGGCEQDCFEGGDGSFRCGCRPGYRLLDDLVSCASRNPCSSSPCRGGATCVPVQLGKDFRCHCPPGYQLDLTGRDCVDVDECQDAPCTQECVNTPGSFRCECWVGYEPGGPGEGACQDVDECAPGRSPCAQGCTNTIGSFSCSCEDGYILAGEEGTQCLDLDECEGQGARRCGGLCLNTEGSFRCGCLPGWELAPDGVSCTGGPTSPAPSAGTPQVQDTGDGEGEHVSSATASSPTGDPEGTSETTWVVPTTGRSSLPRHVRTSLAPPEMLVPSGTRSVWSPVGPLATPGQRESTGDDFTAKHSDSGTDGQKLLLFYILGTVVAILLLLALALGLLVYRKRRAKREEKEKPKNAADSYAWVPERAESRAAENPYSPTPGTDC", "length": 646 }, "evidence": [ { "id": "E1BGJ5", "url": "https://omabrowser.org/oma/group/E1BGJ5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O89103-1", "protein_name": "Complement component C1q receptor", "gene_name": "Cd93", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAISTGLFLLLGLLGQPWAGAAADSQAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQQALTQLLKTKAPLEAKMGKFWIGLQREKGNCTYHDLPMRGFSWVGGGEDTAYSNWYKASKSSCIFKRCVSLILDLSLTPHPSHLPKWHESPCGTPEAPGNSIEGFLCKFNFKGMCRPLALGGPGRVTYTTPFQATTSSLEAVPFASVANVACGDEAKSETHYFLCNEKTPGIFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGMCHSVPLSENYTCRCPSGYQLDSSQVHCVDIDECQDSPCAQDCVNTLGSFHCECWVGYQPSGPKEEACEDVDECAAANSPCAQGCINTDGSFYCSCKEGYIVSGEDSTQCEDIDECSDARGNPCDSLCFNTDGSFRCGCPPGWELAPNGVFCSRGTVFSELPARPPQKEDNDDRKESTMPPTEMPSSPSGSKDVSNRAQTTGLFVQSDIPTASVPLEIEIPSEVSDVWFELGTYLPTTSGHSKPTHEDSVSAHSDTDGQNLLLFYILGTVVAISLLLVLALGILIYHKRRAKKEEIKEKKPQNAADSYSWVPERAESQAPENQYSPTPGTDC", "length": 644 }, "evidence": [ { "id": "E1BGJ5", "url": "https://omabrowser.org/oma/group/E1BGJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ET61-1", "protein_name": "Complement component C1q receptor", "gene_name": "Cd93", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVTSTGLLLLLGLLGQLWAGAAADSEAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQEALAQLLKTKAPSETKIGKFWIGLQREKGKCTYHDLPMKGFSWVGGGEDTTYSNWYKASKSSCISKRCVSLILDLSLKPHPSHLPKWHESPCGTPDAPGNSIEGFLCKFNFKGMCSPLALGGPGQLTYTTPFQATTSSLKAVPFASVANVVCGDEAESKTNYYLCKETTAGVFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGMCHSVPLSENYTCHCPRGYQLDSSQVHCVDIDECEDSPCDQECINTPGGFHCECWVGYQSSGSKEEACEDVDECTAAYSPCAQGCTNTDGSFYCSCKEGYIMSGEDSTQCEDIDECLGNPCDTLCINTDGSFRCGCPAGFELAPNGVSCTRGSMFSELPARPPQKEDKGDGKESTVPLTEMPGSLNGSKDVSNRAQTTDLSIQSDSSTASVPLEIEVSSEASDVWLDLGTYLPTTSGHSQPTHEDSVPAHSDSDTDGQKLLLFYILGTVVAISLLLALALGLLIYLKRKAKKEEIKEKKAQNAADSYSWIPERAESRAPENQYSPTPGTDC", "length": 643 }, "evidence": [ { "id": "E1BGJ5", "url": "https://omabrowser.org/oma/group/E1BGJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NPY3-1", "protein_name": "Complement component C1q receptor", "gene_name": "CD93", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNLATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALALGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC", "length": 652 }, "evidence": [ { "id": "E1BGJ5", "url": "https://omabrowser.org/oma/group/E1BGJ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ5", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ5", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ5", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ5", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ5", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ5", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ5", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" } ], "pmid": "" }, { "name": "complement component C1q complex binding", "id": "GO:0001849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001849", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ5", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "E1BGJ5", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGJ5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 648, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGJ5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGJ5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 164, "start_aa": "Ala", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BGJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGJ5" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 299, "end_pos": 337, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 538, 643 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGL8-1", "uniprot_ac": "E1BGL8", "uniprot_id": "E1BGL8_BOVIN", "mass": { "chemical_mass": 183993.0, "monoisotopic_mass": 183993.0 }, "refseq": { "ac": "XP_024856845", "name": "sialoadhesin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024856845" }, "gene_names": [ { "name": "SIGLEC1", "type": "recommended", "evidence": [ { "id": "E1BGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGL8" } ] }, { "name": "SIGLEC1", "type": "synonym", "evidence": [ { "id": "XP_024856845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024856845" } ] } ], "protein_names": [ { "name": "Sialoadhesin", "type": "recommended", "evidence": [ { "id": "E1BGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGL8/entry#names_and_taxonomy" } ] }, { "name": "Sialic acid-binding Ig-like lectin 1", "type": "synonym", "evidence": [ { "id": "E1BGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGL8/entry#names_and_taxonomy" } ] }, { "name": "sialoadhesin", "type": "synonym", "evidence": [ { "id": "XP_024856845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024856845" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGL8", "url": "https://www.uniprot.org/uniprotkb/E1BGL8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SIGLEC1", "url": "https://www.uniprot.org/uniprotkb/E1BGL8", "locus": { "chromosome": "13", "start_pos": 51505266, "end_pos": 51481265, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013167", "url": "https://www.ensembl.org/id/ENSBTAG00000013167" } ] } } ], "crossref": [ { "id": "ENSBTAG00000013167", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013167", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539759", "url": "https://www.ncbi.nlm.nih.gov/gene/539759", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539759", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539759", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VTFNSQK", "url": "https://omabrowser.org/oma/group/VTFNSQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGL8", "url": "https://www.orthodb.org/?gene=E1BGL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47243:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47243:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024856845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024856845", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BGL8", "url": "https://www.uniprot.org/uniprotkb/E1BGL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGL8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFLLQLLLLALPIPADLISWGVSSPETVKGMKGSCLVIPCTFSFPASVNVPDGITTIWYYDYSGRRQVVSHSTKPQLVEARFQGRAQMVGNPELRVCNLLLKDLQPEDSGSYNFRFEISEGNRWVDVKGTAVTVTEELIMPTVASLAELHEGMEVDFNCSTPYACLQEPVTLRWQGQDPARSTTSTLQKFEPTGIHHQETLHMALSWQDHGRTLSCQLSAANHKTQREIHLQVQYAPKGVEILLSPSGRNILPGDLVTLICQVNSSHPQVSSVQWVKDGTRLKNRSRVLQLPRAAWADAGVYTCEAGNGVGSSVSPPVSLHIFMAAVQVSPAGSILENQTVTLACNTPKEAPRELRYAWYKNHELMKATHSRILQLHSVTRADTGFYFCEVQNAQGRERSDPVSVVVRHPPLTPHLTAFLETQEGLVGILQCSVVSDPLATLVLSHEGLVLASTSGEGDQSPRFSVYSAPNALRLEIRDLGPTDSGEYMCSATNSLGNSSSTLDFHANVARLLISPAAEVAEGQVVTLSCRSSLSPMPDTRFSWYRNGALLLEGPSSSLLLPVVSSTDAGSYHCRAQDGHGTSGLSSPAVLTVLYAPRRPTFTAQLDPDTAGAGQRGLLLCRVDSDPPAQLRLFHRGRVVASSLPSGGSCSACGSCSPRTKVTRAPNLLRVEIQDPVLEDEGVYLCEASNALGNASASANFNAQATVLVITPSHTLQEGTGANLTCRVSREAGGPANFTWFRDGALWAQGPLETLTLLPVARTDAALYACRILTEAGAQLSTPVVLQVLYPPDPPKLSALLDVDQGHTAVFVCTVDSRPPAQLALFHGEHLLATSPGPQLPSRGHLQAKTTANFLQLEVQDLSLKDSGSYRCEANNALGSSNTSLFFQVRGAWVQVSPSPELREGQAVVLSCQVPTGVLEGTSYRWYRDGQPLQEFTSATIRFAAITLSQAGAYHCQAQAPGSATTNLAAPVSLHVSYAPRQATLTTLMDTGPGRLGLLLCRVNSDPPAQLRLLHRDRLVTSTLQGVGELAGSSPRLQVAVAPNTLRLEIHNAVLEDEGVYTCEATNALGQALASATFDAQAVSVQVWPKATVQEGQLVNLTCLVWTTLTQLTYTWYQDGQQRPDAAQSIALPNVTVVDATSYSCGVLIPGQTLHRSRPVTLDVLYAPRSLRLTYLLESRGGQLALVLCTVDSRPPAQLVLSHAGRLLASSTTASVPNTLQLELWEPGPSDEGLYSCSAHSPLGQVNTSLELRLEVVQVTLAPSATVPEGAPITVSCEDPAARPPTLYAWYHNSRWLQEGPEASLSFPVVTRAHAGAYTCQVRDAQGTRSSRPTALHVLYAPRDAAVSSFWDSRSSPMAVVQCTVDSEPPAELALARNGKVLATSNGIPGLAVETGHVQVARNALRLRVQAVPSGDEDTYVCTARNLLGSVSTTLGQMQAEGVHVVAEPGLDVPEGAALNLSCQLPGGPGLMGNSTFTWFWNGRRLHTEPVPTVAFTHVARDQAGMYHCQAELPTGATASAPVTLRVLYPPKTPTMTVFVEPEGGIQGILDCRVDSEPLASLTLHLGSRLVASSQSKVAPAKPHIHVSVTPNALRVVIEELRPSDQGEYVCSASNSLGSASAATYFGTRALHRLQLFQQLLWVLGLLAGLLSLLLGLGAYYTWRRRNFHKLREGENSVEMASQKETMQEEEVTRICDDSDPVNNAALGPDSL", "length": 1713, "header": "tr|E1BGL8-1|E1BGL8_BOVIN Isoform 1 of Sialoadhesin OS=Bos taurus OX=9913 GN=SIGLEC1 PE=3 SV=3 CANONICAL=E1BGL8-1" }, "isoforms": [ { "isoform_ac": "E1BGL8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGL8/entry#E1BGL8-1", "sequence": { "sequence": "MDFLLQLLLLALPIPADLISWGVSSPETVKGMKGSCLVIPCTFSFPASVNVPDGITTIWYYDYSGRRQVVSHSTKPQLVEARFQGRAQMVGNPELRVCNLLLKDLQPEDSGSYNFRFEISEGNRWVDVKGTAVTVTEELIMPTVASLAELHEGMEVDFNCSTPYACLQEPVTLRWQGQDPARSTTSTLQKFEPTGIHHQETLHMALSWQDHGRTLSCQLSAANHKTQREIHLQVQYAPKGVEILLSPSGRNILPGDLVTLICQVNSSHPQVSSVQWVKDGTRLKNRSRVLQLPRAAWADAGVYTCEAGNGVGSSVSPPVSLHIFMAAVQVSPAGSILENQTVTLACNTPKEAPRELRYAWYKNHELMKATHSRILQLHSVTRADTGFYFCEVQNAQGRERSDPVSVVVRHPPLTPHLTAFLETQEGLVGILQCSVVSDPLATLVLSHEGLVLASTSGEGDQSPRFSVYSAPNALRLEIRDLGPTDSGEYMCSATNSLGNSSSTLDFHANVARLLISPAAEVAEGQVVTLSCRSSLSPMPDTRFSWYRNGALLLEGPSSSLLLPVVSSTDAGSYHCRAQDGHGTSGLSSPAVLTVLYAPRRPTFTAQLDPDTAGAGQRGLLLCRVDSDPPAQLRLFHRGRVVASSLPSGGSCSACGSCSPRTKVTRAPNLLRVEIQDPVLEDEGVYLCEASNALGNASASANFNAQATVLVITPSHTLQEGTGANLTCRVSREAGGPANFTWFRDGALWAQGPLETLTLLPVARTDAALYACRILTEAGAQLSTPVVLQVLYPPDPPKLSALLDVDQGHTAVFVCTVDSRPPAQLALFHGEHLLATSPGPQLPSRGHLQAKTTANFLQLEVQDLSLKDSGSYRCEANNALGSSNTSLFFQVRGAWVQVSPSPELREGQAVVLSCQVPTGVLEGTSYRWYRDGQPLQEFTSATIRFAAITLSQAGAYHCQAQAPGSATTNLAAPVSLHVSYAPRQATLTTLMDTGPGRLGLLLCRVNSDPPAQLRLLHRDRLVTSTLQGVGELAGSSPRLQVAVAPNTLRLEIHNAVLEDEGVYTCEATNALGQALASATFDAQAVSVQVWPKATVQEGQLVNLTCLVWTTLTQLTYTWYQDGQQRPDAAQSIALPNVTVVDATSYSCGVLIPGQTLHRSRPVTLDVLYAPRSLRLTYLLESRGGQLALVLCTVDSRPPAQLVLSHAGRLLASSTTASVPNTLQLELWEPGPSDEGLYSCSAHSPLGQVNTSLELRLEVVQVTLAPSATVPEGAPITVSCEDPAARPPTLYAWYHNSRWLQEGPEASLSFPVVTRAHAGAYTCQVRDAQGTRSSRPTALHVLYAPRDAAVSSFWDSRSSPMAVVQCTVDSEPPAELALARNGKVLATSNGIPGLAVETGHVQVARNALRLRVQAVPSGDEDTYVCTARNLLGSVSTTLGQMQAEGVHVVAEPGLDVPEGAALNLSCQLPGGPGLMGNSTFTWFWNGRRLHTEPVPTVAFTHVARDQAGMYHCQAELPTGATASAPVTLRVLYPPKTPTMTVFVEPEGGIQGILDCRVDSEPLASLTLHLGSRLVASSQSKVAPAKPHIHVSVTPNALRVVIEELRPSDQGEYVCSASNSLGSASAATYFGTRALHRLQLFQQLLWVLGLLAGLLSLLLGLGAYYTWRRRNFHKLREGENSVEMASQKETMQEEEVTRICDDSDPVNNAALGPDSL", "length": 1713, "header": "tr|E1BGL8-1|E1BGL8_BOVIN Isoform 1 of Sialoadhesin OS=Bos taurus OX=9913 GN=SIGLEC1 PE=3 SV=3 CANONICAL=E1BGL8-1" }, "locus": { "chromosome": "13", "start_pos": 51504262, "end_pos": 51487534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017523.7", "url": "https://www.ensembl.org/id/ENSBTAT00000017523.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017523.5", "url": "https://www.ensembl.org/id/ENSBTAP00000017523.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 484, "start_aa": "Thr", "end_pos": 484, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr484", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539759", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539759", "resource": "KEGG Pathway" }, { "id": "R-BTA-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K320-1", "protein_name": "Sialoadhesin", "gene_name": "Siglec1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HLRTRMCALLSLLLLASVFTPGQTTWGVSSPKDVQGLTGSCLLIPCIFSFPADVSVPNGITAIWYYDYSGKRQVVIHSGDPKLVDERFRGRAELTGNMDHKVCNLLLKDLKLEDSGTYNFRFEISDGNRWSDVRGTTVTVTKDPSPPTITIPHELREGVEVNVNCSTPYLCLQEKQVSLHWQGQDPTRSVISNFQSLEPTGVYHQTTLHMAPSWQDHRRTLRCQLSLATHSSQKEVYLQVQHAPKGVEILLSSSGRNILPGNLVTLTCRVNSSYPAVSSVDWVKDGVNLTAKGHVLQLSSATWNDSGVYTCQATNNVGSLASPPLSLHVFMAEVKINPAGPILENETVTLLCSTPKEAPQELRYSWYKNNILLEDAHAPTLHLPAVTRADTGFYFCEVQNTQGSERSGPVSVVVRYPPLTPDLTTFLETQAGLVGIFHCSVISEPLATVVLSHGGLTLASSSGENDFNPRFSISSAPNSVRLEIRDLQPADSGEYTCSATNSLGKSMSSLDFHANVARLLISPSKEVVEGQAVTLSCRSGLNPAPDTRFSWYLNGALLLEGSSSNFLLPAASSTDSGSYYCRARAGPHTSGPSLPTVLTVFYPPRKLTFTARLDLDTSGDGDGRRGILLCQVDSDPPAQLQLLHKGHVVATSLPSMCGSCSRRMKVSRASNSLQVEIQKPVLEDEGMYLCEASNTLGNSSVSASFNAKATVVVITPSDTLLEGTEASLTCNVTQEVAVSPANFSWFRNGVLWTQGPLETVRLQPLARTDAAVYACRLLTDDGAQLSAPVVLSVQYAPDPPKLSALLDVGQGHMAVFICTVDSYPLAHLSLFRGERLLATSLEPQRLSHGRIQAKATANSLQLEVRELGLEDSGNYHCEATNVLGSANSSLFFQVRGAWVQVSPSPELREGQAVVLSCQVPTGVPEGTSYRWFQDGRPLQESTSSILRIAAISLRQAGAYHCQAQAPDTAAASLAAPVSLHVSYTPRHVTLSALLSTGPGRYGHLVCSAQSDPPALLRLFHQNRLVASTLQGPEELASSNPRLHVAVSSNELRLEIQFTELEDGGTYTCEATNTLGQASATADFDAQAVRVAVWPNATVQEGQQVNLSCLAWSTHQDSLSYTWYKGGQQLLGVRSISLPSVTVSDATSYRCGVGLPGHTPHLSRPVTLDVLYAPRSLQLTYLLESQGRRLALVLCTVDSRPPAQLTLSHGGQLLASSTEASVPNTLRLELQDPKPSDEGLYSCSAQSPLGKVNTSLALRLEGVRVRMNPSATVPEGEPVTVTCEDPAALSPALYAWFHNGHWLQEGPASSLQFPVTTQAHAGAYFCQVHDTQGTRSSRPASLQILYAPRDAVLSSFRDSRTRHMVVIQCTVDSEPPAELVLSRNSKVLAASRELHSSAPGISHVQAARNALRLQVQDTTFGDGNTYVCTARNTLGSISTTHKLLRETDIHVTAEPGLDVPEGTALNLSCHLPGGSQPVGNSSFTWFWNRHLLHSAPVPTLSFTPVVRAQAGSYHCRAELSTGVTTSPPVMLRVLYPPKTPTLTVFVEPQGGHQGILDCRVDSEPLASLTLQLGSQLVASNQPHSAPTQPHIRVTAPPNALRLDIEELGPNNQGEYVCTASNALGSASASAYFGTRALQQLQLFQRLLWVLGFLAGFLGLLLGLGACYSWRKKNSSKLNVNENSAEMTTQKDNIQEETVAAV", "length": 1700 }, "evidence": [ { "id": "E1BGL8", "url": "https://omabrowser.org/oma/group/E1BGL8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BZZ2-1", "protein_name": "Sialoadhesin", "gene_name": "SIGLEC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFLPKLLLLASFFPAGQASWGVSSPQDVQGVKGSCLLIPCIFSFPADVEVPDGITAIWYYDYSGQRQVVSHSADPKLVEARFRGRTEFMGNPEHRVCNLLLKDLQPEDSGSYNFRFEISEVNRWSDVKGTLVTVTEEPRVPTIASPVELLEGTEVDFNCSTPYVCLQEQVRLQWQGQDPARSVTFNSQKFEPTGVGHLETLHMAMSWQDHGRILRCQLSVANHRAQSEIHLQVKYAPKGVKILLSPSGRNILPGELVTLTCQVNSSYPAVSSIKWLKDGVRLQTKTGVLHLPQAAWSDAGVYTCQAENGVGSLVSPPISLHIFMAEVQVSPAGPILENQTVTLVCNTPNEAPSDLRYSWYKNHVLLEDAHSHTLRLHLATRADTGFYFCEVQNVHGSERSGPVSVVVNHPPLTPVLTAFLETQAGLVGILHCSVVSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGPNSLRLEIRDLEETDSGEYKCSATNSLGNATSTLDFHANAARLLISPAAEVVEGQAVTLSCRSGLSPTPDARFSWYLNGALLHEGPGSSLLLPAASSTDAGSYHCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLDLDAAGAGAGRRGLLLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTKAPNLLRVEIHNPLLEEEGLYLCEASNALGNASTSATFNGQATVLAIAPSHTLQEGTEANLTCNVSREAAGSPANFSWFRNGVLWAQGPLETVTLLPVARTDAALYACRILTEAGAQLSTPVLLSVLYPPDRPKLSALLDMGQGHMALFICTVDSRPLALLALFHGEHLLATSLGPQVPSHGRFQAKAEANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPELQEGQAVVLSCQVHTGVPEGTSYRWYRDGQPLQESTSATLRFAAITLTQAGAYHCQAQAPGSATTSLAAPISLHVSYAPRHVTLTTLMDTGPGRLGLLLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRLEIHGAMLEDEGVYICEASNTLGQASASADFDAQAVNVQVWPGATVREGQLVNLTCLVWTTHPAQLTYTWYQDGQQRLDAHSIPLPNVTVRDATSYRCGVGPPGRAPRLSRPITLDVLYAPRNLRLTYLLESHGGQLALVLCTVDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANTSLELRLEGVRVILAPEAAVPEGAPITVTCADPAAHAPTLYTWYHNGRWLQEGPAASLSFLVATRAHAGAYSCQAQDAQGTRSSRPAALQVLYAPQDAVLSSFRDSRARSMAVIQCTVDSEPPAELALSHDGKVLATSSGVHSLASGTGHVQVARNALRLQVQDVPAGDDTYVCTAQNLLGSISTIGRLQVEGARVVAEPGLDVPEGAALNLSCRLLGGPGPVGNSTFAWFWNDRRLHAEPVPTLAFTHVARAQAGMYHCLAELPTGAAASAPVMLRVLYPPKTPTMMVFVEPEGGLRGILDCRVDSEPLASLTLHLGSRLVASSQPQGAPAEPHIHVLASPNALRVDIEALRPSDQGEYICSASNVLGSASTSTYFGVRALHRLHQFQQLLWVLGLLVGLLLLLLGLGACYTWRRRRVCKQSMGENSVEMAFQKETTQLIDPDAATCETSTCAPPLG", "length": 1709 }, "evidence": [ { "id": "E1BGL8", "url": "https://omabrowser.org/oma/group/E1BGL8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "E1BGL8", "url": "https://www.uniprot.org/uniprotkb/E1BGL8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BGL8", "url": "https://www.uniprot.org/uniprotkb/E1BGL8" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "E1BGL8", "url": "https://www.uniprot.org/uniprotkb/E1BGL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "E1BGL8", "url": "https://www.uniprot.org/uniprotkb/E1BGL8" } ], "pmid": "" }, { "name": "negative regulation of type I interferon production", "id": "GO:0032480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032480", "evidence": [ { "database": "UniProtKB", "id": "E1BGL8", "url": "https://www.uniprot.org/uniprotkb/E1BGL8" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis of virus by host cell", "id": "GO:0075512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075512", "evidence": [ { "database": "UniProtKB", "id": "E1BGL8", "url": "https://www.uniprot.org/uniprotkb/E1BGL8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "E1BGL8", "url": "https://www.uniprot.org/uniprotkb/E1BGL8" } ], "pmid": "" }, { "name": "virion binding", "id": "GO:0046790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046790", "evidence": [ { "database": "UniProtKB", "id": "E1BGL8", "url": "https://www.uniprot.org/uniprotkb/E1BGL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1101, "end_pos": 1103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1135, "end_pos": 1137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1248, "end_pos": 1250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1461, "end_pos": 1463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1475, "end_pos": 1477, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 695, "end_pos": 697, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" }, { "start_pos": 883, "end_pos": 885, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGL8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 142, "end_pos": 231, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 484 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1101, "end_pos": 1103 }, { "start_pos": 1135, "end_pos": 1137 }, { "start_pos": 1248, "end_pos": 1250 }, { "start_pos": 1461, "end_pos": 1463 }, { "start_pos": 1475, "end_pos": 1477 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 695, "end_pos": 697 }, { "start_pos": 724, "end_pos": 726 }, { "start_pos": 738, "end_pos": 740 }, { "start_pos": 883, "end_pos": 885 } ] }, "class_list": [], "section_stats": [ { 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"https://www.uniprot.org/uniprotkb/E1BGM6" } ] }, { "name": "HOXB2", "type": "synonym", "evidence": [ { "id": "NP_001178264", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178264" } ] } ], "protein_names": [ { "name": "Homeobox B2", "type": "synonym", "evidence": [ { "id": "E1BGM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGM6/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein Hox-B2", "type": "synonym", "evidence": [ { "id": "NP_001178264", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178264" } ] } ], "function": [ { "annotation": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.", "evidence": [ { "database": "UniProtKB", "id": "E1BGM6", "url": "https://www.uniprot.org/uniprotkb/E1BGM6#function" }, { "database": "UniProtKB", "id": "ARBA00003263", "url": "https://www.uniprot.org/uniprotkb/ARBA00003263#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGM6", "url": "https://www.uniprot.org/uniprotkb/E1BGM6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HOXB2", "url": "https://www.uniprot.org/uniprotkb/E1BGM6", "locus": { "chromosome": "19", "start_pos": 37948660, "end_pos": 37946201, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009979", "url": "https://www.ensembl.org/id/ENSBTAG00000009979" } ] } } ], "crossref": [ { "id": "E1BGM6", "url": "https://alphafold.ebi.ac.uk/entry/E1BGM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009979", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009979", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616129", "url": "https://www.ncbi.nlm.nih.gov/gene/616129", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616129", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616129", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DLPHFNF", "url": "https://omabrowser.org/oma/group/DLPHFNF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGM6", "url": "https://www.orthodb.org/?gene=E1BGM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45664", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45664", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45664:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45664:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178264", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178264", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BGM6", "url": "https://www.uniprot.org/uniprotkb/E1BGM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGM6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQTFPSLQPGASTLQRPGSQKRAEDGPALPPLPPLPAAPLAPEFPWMKEKKSAKKPSQSAASPPAASSVLASGVGSPADGPGLPEAAGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALRNTGEPAEEPVASPGRPSVLQASRAACCLTPEVAQGPPGVSGPRALAARVEGADARSPGGALRGAGGREPEPLPEDAFSERQDSPFLPDLSFFAADSCLQLSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 354, "header": "tr|E1BGM6-1|E1BGM6_BOVIN Isoform 1 of Homeobox B2 OS=Bos taurus OX=9913 GN=HOXB2 PE=3 SV=1 CANONICAL=E1BGM6-1" }, "isoforms": [ { "isoform_ac": "E1BGM6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGM6/entry#E1BGM6-1", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQTFPSLQPGASTLQRPGSQKRAEDGPALPPLPPLPAAPLAPEFPWMKEKKSAKKPSQSAASPPAASSVLASGVGSPADGPGLPEAAGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALRNTGEPAEEPVASPGRPSVLQASRAACCLTPEVAQGPPGVSGPRALAARVEGADARSPGGALRGAGGREPEPLPEDAFSERQDSPFLPDLSFFAADSCLQLSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 354, "header": "tr|E1BGM6-1|E1BGM6_BOVIN Isoform 1 of Homeobox B2 OS=Bos taurus OX=9913 GN=HOXB2 PE=3 SV=1 CANONICAL=E1BGM6-1" }, "locus": { "chromosome": "19", "start_pos": 37948229, "end_pos": 37946400, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013159.5", "url": "https://www.ensembl.org/id/ENSBTAT00000013159.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013159.3", "url": "https://www.ensembl.org/id/ENSBTAP00000013159.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616129", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616129", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MGM8-1", "protein_name": "Homeobox protein Hox-B2", "gene_name": "Hoxb2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPLEQTYPSLQPGASTLQRPGSQKQAEDGPALRPPPPLAAPPAPEFPWMKEKKSAKKPSQSAASPSPAASSVRVSGVGSPSDGPGLSESGGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGDPGGPSAPDDSGDPAEESAVSPGPASASHRLREACFLPAEAAQGPQGAPPPAPPATSLESMGAPSPGCTMLRARGLQPETLPEDTCPEQPDSPFLPDLNFFAADSCLQMSGGLSPSLQSSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 354 }, "evidence": [ { "id": "E1BGM6", "url": "https://omabrowser.org/oma/group/E1BGM6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A426-1", "protein_name": "Homeobox B2", "gene_name": "Hoxb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPPLEQTFPSLQLGASTLQRPGSQKPAGDGPALRPPPPLPVAPPAPEFPWMKEKKSAKKPSQSAATPSPAASSVRASGVGSPSDGPGLPESGGSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPGGLSAQDDAGEPAEEPTVSPGDVASHRLREACFLPAEAAQGPRGAPPPLPPATALESVGASSPGCTMLRAGGLQSEPLPEDACPERQDSPFLPDLNFFAADSCLPMSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 355 }, "evidence": [ { "id": "E1BGM6", "url": "https://omabrowser.org/oma/group/E1BGM6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RWG7-1", "protein_name": "Homeobox B2", "gene_name": "HOXB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPSPPPFEQTFPSLQPGASTLQRPGSQKRAEDGPALPPPPPPLPATPLAPEFPWMKEKKSAKKPSQSATSPTAAFSVLASGVGSPADGPGLPEAAGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGGPACPGAPKKAGEASEEPLASPGRPSVSRAAREVCCQPPEVAPGPLGAPGLRPLAARVEGAGARSPGGELRGAGGLEPERLPEDAFPERPYSPFLPDLSFFAADSCLQLSGGLSPSLSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 353 }, "evidence": [ { "id": "E1BGM6", "url": "https://omabrowser.org/oma/group/E1BGM6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C1T1-1", "protein_name": "Homeobox protein Hox-B2", "gene_name": "Hoxb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPLEQTFPSLQLGASTLQRPGSQKQAGDGPALRSPPPLPVAPPAPEFPWMKEKKSTKKPSQSAASPSPAASSVRASEVGSPSDGPGLPECGGSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPEGEPGGPSAQDDAGEPAEEPTVSPGDVATHRLREACFHPAEAAQGPRGAPPSALPATTLESVGASSPGCTMLRAGGRQSEPLPEDACPERQDSPFLPDLNFFAADSCLQMSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 354 }, "evidence": [ { "id": "E1BGM6", "url": "https://omabrowser.org/oma/group/E1BGM6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P14652-1", "protein_name": "Homeobox protein Hox-B2", "gene_name": "HOXB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQTFPSLQPGASTLQRPRSQKRAEDGPALPPPPPPPLPAAPPAPEFPWMKEKKSAKKPSQSATSPSPAASAVPASGVGSPADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALEDICDPAEEPAASPGGPSASRAAWEACCHPPEVVPGALSADPRPLAVRLEGAGASSPGCALRGAGGLEPGPLPEDVFSGRQDSPFLPDLNFFAADSCLQLSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 356 }, "evidence": [ { "id": "E1BGM6", "url": "https://omabrowser.org/oma/group/E1BGM6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GLI3-1", "protein_name": "Homeobox B2", "gene_name": "HOXB2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSLPAVLETFQTSSIKDSTLIPPPFEQTVLSLNPCSSSQARPRSQKRASHGLLQPQPPAQPGPLAAEFPWMKEKKSSKKATQAPSSSSSSFPPSSSSVPIPAAGSPADTQGLADSSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQYKEPPDGDIAYPGLDEGSEATDEAEESPALGPCPGPYRGAQPEQPRSPRGTDRPGAPPSELGFPESQGSPWLPELSILSAESCLQLSPALQDSLESPLHFSEEDLDFFTSALCTIDLQHFNFQ", "length": 323 }, "evidence": [ { "id": "E1BGM6", "url": "https://omabrowser.org/oma/group/E1BGM6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BGM6", "url": "https://www.uniprot.org/uniprotkb/E1BGM6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BGM6", "url": "https://www.uniprot.org/uniprotkb/E1BGM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BGM6", "url": "https://www.uniprot.org/uniprotkb/E1BGM6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BGM6", "url": "https://www.uniprot.org/uniprotkb/E1BGM6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BGM6", "url": "https://www.uniprot.org/uniprotkb/E1BGM6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BGM6", "url": "https://www.uniprot.org/uniprotkb/E1BGM6" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BGM6", "url": "https://www.uniprot.org/uniprotkb/E1BGM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGM6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 354, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGM6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGM6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGM6" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 198, "start_aa": "Gly", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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Annotation" ] }, { "id": "IPR006762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539009", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539009", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFKHACS", "url": "https://omabrowser.org/oma/group/AFKHACS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGP6", "url": "https://www.orthodb.org/?gene=E1BGP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11259", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11259", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11259:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11259:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024852022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BGP6", "url": "https://www.uniprot.org/uniprotkb/E1BGP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGP6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECACFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAQIIEADEVLLFERATFLVISHYQCKEQRDVHRFEKISNIIKQFKLSCSKLATSFQSMEVRNSNFAAFIDIFTSNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKHRLLMR", "length": 313, "header": "tr|E1BGP6-1|E1BGP6_BOVIN Isoform 1 of Ras-related GTP-binding protein OS=Bos taurus OX=9913 GN=LOC539009 PE=3 SV=3 CANONICAL=E1BGP6-1" }, "isoforms": [ { "isoform_ac": "E1BGP6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGP6/entry#E1BGP6-1", "sequence": { "sequence": "MPNTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECACFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAQIIEADEVLLFERATFLVISHYQCKEQRDVHRFEKISNIIKQFKLSCSKLATSFQSMEVRNSNFAAFIDIFTSNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKHRLLMR", "length": 313, "header": "tr|E1BGP6-1|E1BGP6_BOVIN Isoform 1 of Ras-related GTP-binding protein OS=Bos taurus OX=9913 GN=LOC539009 PE=3 SV=3 CANONICAL=E1BGP6-1" }, "locus": { "chromosome": "8", "start_pos": 71367355, "end_pos": 71366417, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000057306.4", "url": "https://www.ensembl.org/id/ENSBTAT00000057306.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048674.3", "url": "https://www.ensembl.org/id/ENSBTAP00000048674.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539009", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539009", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061HXU8-1", "protein_name": "Ras-related GTP-binding protein", "gene_name": "Rragb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEESDSEKKTEKENLGPGVQPPLGEPEGSLGWTMPNASMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGTTILDRIHSLQINSSLSTYSLVDSVGNTKTFDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPEAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECSCFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATFLVISHYQCKEQRDAHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKQCLLMR", "length": 374 }, "evidence": [ { "id": "E1BGP6", "url": "https://omabrowser.org/oma/group/E1BGP6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q63487-1", "protein_name": "Ras-related GTP-binding protein B", "gene_name": "RragB", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEESDSEKKTEKENVGPKVEPPLGEPEGSLGWAMPNAAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATILDRIHSLQINSSLSTYSLVDSVGNTKTFDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPEAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECSCFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATFLVISHYQCKEQRDAHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKQCLLMR", "length": 374 }, "evidence": [ { "id": "E1BGP6", "url": "https://omabrowser.org/oma/group/E1BGP6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NTA4-1", "protein_name": "Ras-related GTP-binding protein B", "gene_name": "Rragb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEESDSEKKTEKENVGPKVEPPLGEPEGSLGWAMPNAAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATILDRIHSLQINSSLSTYSLVDSVGNTKTFDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPEAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECSCFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATFLVISHYQCKEQRDAHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKQCLLMR", "length": 374 }, "evidence": [ { "id": "E1BGP6", "url": "https://omabrowser.org/oma/group/E1BGP6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "E1BGP6", "url": "https://www.uniprot.org/uniprotkb/E1BGP6" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "E1BGP6", "url": "https://www.uniprot.org/uniprotkb/E1BGP6" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "E1BGP6", "url": "https://www.uniprot.org/uniprotkb/E1BGP6" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "E1BGP6", "url": "https://www.uniprot.org/uniprotkb/E1BGP6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "E1BGP6", "url": "https://www.uniprot.org/uniprotkb/E1BGP6" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "E1BGP6", "url": "https://www.uniprot.org/uniprotkb/E1BGP6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BGP6", "url": "https://www.uniprot.org/uniprotkb/E1BGP6" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "E1BGP6", "url": "https://www.uniprot.org/uniprotkb/E1BGP6" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "E1BGP6", "url": "https://www.uniprot.org/uniprotkb/E1BGP6" } ], "pmid": "" }, { "name": "Gtr1-Gtr2 GTPase complex", "id": "GO:1990131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990131", "evidence": [ { "database": "UniProtKB", "id": "E1BGP6", "url": "https://www.uniprot.org/uniprotkb/E1BGP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08E00-1", "Q5E9J3-1", "A6QP66-1", "Q2KHU8-1", "Q2KIA5-1", "F1MM29-1", "P08239-1", "P04896-1", "P63097-1", "Q7YS69-1", "Q0VCJ7-1", "A0AAA9SVR8-1", "P81948-1", "Q2KJ93-1", "A0AAA9TES1-1", "P61223-1", "Q2HJB8-1", "Q0IIG7-1", "Q3ZCJ7-1", "Q27957-1", "Q2HJ86-1", "A0A3Q1LMP2-1", "F1MB25-1", "Q58DS9-1", "A0AAA9S306-1", "A0A3Q1NEF8-1", "A4FV54-1", "A6H7I5-1", "F2Z4D5-1", "G3N1U2-1", "O18956-1", "P62998-1", "Q32KN8-1", "Q3MHP2-1", "Q3T054-1", "Q3T0F5-1", "Q3T0T7-1", "Q56JV3-1", "F1MNI4-1", "Q8HZJ5-1", "P61585-1", "P62833-1", "P68103-1", "Q08DI5-1", "Q2HJH2-1", "Q2T9U1-1", "Q2TBH7-1", "Q3MHP5-1", "Q3SX43-1", "Q3SYU2-1", "P81947-1", "P84080-1", "Q08DF4-1", "Q2KI07-1", "Q2TA29-1", "Q3T0D7-1", "A6QLJ3-1", "A6QNM2-1", "A6QR46-1", "Q1LZ78-1", "Q2KHZ2-1", "G3MYK6-1", "Q58D56-1", "Q32KW9-1", "P11023-1", "Q58DW6-1", "Q9TU25-1", "P10948-1", "Q2HJI8-1", "P10949-1", "Q0IIG8-1", "Q29RR0-1", "Q32PH8-1", "Q58DS5-1", "Q1RMR4-1", "Q3ZC27-1", "P49410-1", "A0A140T898-1", "E1BPU0-1", "A0AAA9S5W8-1", "A0AAA9SLN0-1", "A0AAF6Z672-1", "Q17R06-1", "Q58D72-1", "P82922-1", "Q2HJF8-1", "Q17QU4-1", "Q2YDM7-1", "A0AAA9T9T1-1", "A0A3Q1MDX0-1", "F1N2J9-1", "Q17QB7-1", "Q3SWY9-1", "Q5E9M9-1", "A0A3S5ZPA2-1", "A0AAA9SV95-1", "A0AAA9TWE6-1", "F1N6Y7-1", "F1N7V2-1", "A0AAA9SGM6-1", "A0AAA9TNQ2-1", "A0AAA9TS74-1", "F6Q1G9-1", "A0AAF6YXF5-1", "A5D7J5-1", "P04695-1", "Q3ZBW5-1", "A4FUD1-1", "A0A3Q1M0B9-1", "A6H7F2-1", "F1MHP4-1", "A0A3Q1MGR4-1", "A0A3Q1NCE9-1", "Q0P5E2-1", "Q32LJ6-1", "Q58DC5-1", "Q08DA0-1", "A0ABI0NND0-1", "E1BJA0-1", "A0A3Q1N147-1", "A0AAF6YME1-1", "F1MX39-1", "Q1RMJ6-1", "Q2HJ68-1", "Q2HJG3-1", "Q17QI8-1", "Q3SZA1-1", "A0ABI0NZ89-1", "A0ABI0P4Y3-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A140T898", "gene_name": "RAB13", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] } ] }, { "uniprot_ac": "A0A3Q1LMP2", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B9", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] } ] }, { "uniprot_ac": "A0A3Q1MDX0", "gene_name": "DNM3", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] } ] }, { "uniprot_ac": "A0A3Q1MGR4", "gene_name": "RAB37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] } ] }, { "uniprot_ac": "A0A3Q1N147", "gene_name": "RAB1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] } ] }, { "uniprot_ac": "A0A3Q1NCE9", "gene_name": 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During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "E1BGR6", "url": "https://www.uniprot.org/uniprotkb/E1BGR6#function" }, { "database": "UniProtKB", "id": "ARBA00045441", "url": "https://www.uniprot.org/uniprotkb/ARBA00045441#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGR6", "url": "https://www.uniprot.org/uniprotkb/E1BGR6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": 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"sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGT6-1", "uniprot_ac": "E1BGT6", "uniprot_id": "E1BGT6_BOVIN", "mass": { "chemical_mass": 80544.0, "monoisotopic_mass": 80544.0 }, "refseq": { "ac": "NP_001192497", "name": "pseudouridylate synthase PUS7L", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192497" }, "gene_names": [ { "name": "PUS7L", "type": "recommended", "evidence": [ { "id": "E1BGT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGT6" } ] }, { "name": "PUS7L", "type": "synonym", "evidence": [ { "id": "NP_001192497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192497" } ] } ], "protein_names": [ { "name": "Pseudouridylate synthase PUS7L", "type": "recommended", "evidence": [ { "id": "E1BGT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGT6/entry#names_and_taxonomy" } ] }, { "name": "CG6745-like", "type": "synonym", "evidence": [ { "id": "NP_001192497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192497" } ] }, { "name": "Pseudouridylate synthase 7 homolog-like protein", "type": "synonym", "evidence": [ { "id": "E1BGT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGT6/entry#names_and_taxonomy" } ] }, { "name": "pseudouridylate synthase 7 homolog-like", "type": "synonym", "evidence": [ { "id": "NP_001192497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192497" } ] }, { "name": "pseudouridylate synthase 7 like", "type": "synonym", "evidence": [ { "id": "NP_001192497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192497" } ] }, { "name": "pseudouridylate synthase PUS7L", "type": "synonym", "evidence": [ { "id": "NP_001192497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192497" } ] } ], "function": [ { "annotation": "Pseudouridine synthase that catalyzes pseudouridylation of mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "E1BGT6", "url": "https://www.uniprot.org/uniprotkb/E1BGT6#function" }, { "database": "UniProtKB", "id": "ARBA00057241", "url": "https://www.uniprot.org/uniprotkb/ARBA00057241#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGT6", "url": "https://www.uniprot.org/uniprotkb/E1BGT6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PUS7L", "url": "https://www.uniprot.org/uniprotkb/E1BGT6", "locus": { "chromosome": "5", "start_pos": 36729838, "end_pos": 36710848, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004718", "url": "https://www.ensembl.org/id/ENSBTAG00000004718" } ] } } ], "crossref": [ { "id": "E1BGT6", "url": "https://alphafold.ebi.ac.uk/entry/E1BGT6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004718", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004718", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02576", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02576", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505464", "url": "https://www.ncbi.nlm.nih.gov/gene/505464", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505464", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505464", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPNNKVH", "url": "https://omabrowser.org/oma/group/FPNNKVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGT6", "url": "https://www.orthodb.org/?gene=E1BGT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13326", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13326", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13326:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13326:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01142", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01142", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23943", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23943", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192497", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192497", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "56644", "url": "https://www.rhea-db.org/rhea/56644", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BGT6", "url": "https://www.uniprot.org/uniprotkb/E1BGT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGT6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEDTDFRIRFSSLCFITDHVGFCGTIKSSPSDFIVIEIDEQGELVNKESDKLVYEVSKVLPEPNTLAKKAKLDLQILSFEETSNQEVSTLAGSSSDDHNFVPCSEKEDTIKYRTYKGEEENVDVLGSLLDEKTNELLNQFACNIKEKWDSKTELIGPSPEFSLGRILDKNQRATLHSAIRQKFPFLITVGKNSEIVVRPNLEYKELCHLVSEEEAFDFFKYLDAKKENSKFTFKPDTNKEHRKAVHHFVNKKFGNLVETKSFPELNDSADNPNVVITVRFRVKAHKHCKRSLLECQGRKDIYTAFTLRKENLEMFEAVGFLAVKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIEKEVEKKRMNVFNIRSVEDSLRLGQLKGNHFDIVIRNLKNQINDSANLRERILEAIENVKNKGFVNYYGPQRFGMGRKVHTDQIGLALLKSETVKAVKLFFTPEDLDDPVNRAKKYFLQTEDAKGTLALMPEFKVRERALLESLHRFGVTEEGYIQAWFSFPHSLRIFYVHAYSSKIWNEAVSYRLETYGSRVVEGDLVCLDEDADNEQLPSSKVHLVTEEEESANTYAIHQVVLPVLGCNIQYPKNKVGQWYQEVLSRDGLQTCKFKIPTLKLNVPGCYRKILKHPCNLSYQLMEDHGIDVKKEGSHIDEATLSLLISFDLDASCYATVCLREIMKHDF", "length": 702, "header": "tr|E1BGT6-1|E1BGT6_BOVIN Isoform 1 of Pseudouridylate synthase PUS7L OS=Bos taurus OX=9913 GN=PUS7L PE=3 SV=2 CANONICAL=E1BGT6-1" }, "isoforms": [ { "isoform_ac": "E1BGT6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGT6/entry#E1BGT6-1", "sequence": { "sequence": "MEEDTDFRIRFSSLCFITDHVGFCGTIKSSPSDFIVIEIDEQGELVNKESDKLVYEVSKVLPEPNTLAKKAKLDLQILSFEETSNQEVSTLAGSSSDDHNFVPCSEKEDTIKYRTYKGEEENVDVLGSLLDEKTNELLNQFACNIKEKWDSKTELIGPSPEFSLGRILDKNQRATLHSAIRQKFPFLITVGKNSEIVVRPNLEYKELCHLVSEEEAFDFFKYLDAKKENSKFTFKPDTNKEHRKAVHHFVNKKFGNLVETKSFPELNDSADNPNVVITVRFRVKAHKHCKRSLLECQGRKDIYTAFTLRKENLEMFEAVGFLAVKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIEKEVEKKRMNVFNIRSVEDSLRLGQLKGNHFDIVIRNLKNQINDSANLRERILEAIENVKNKGFVNYYGPQRFGMGRKVHTDQIGLALLKSETVKAVKLFFTPEDLDDPVNRAKKYFLQTEDAKGTLALMPEFKVRERALLESLHRFGVTEEGYIQAWFSFPHSLRIFYVHAYSSKIWNEAVSYRLETYGSRVVEGDLVCLDEDADNEQLPSSKVHLVTEEEESANTYAIHQVVLPVLGCNIQYPKNKVGQWYQEVLSRDGLQTCKFKIPTLKLNVPGCYRKILKHPCNLSYQLMEDHGIDVKKEGSHIDEATLSLLISFDLDASCYATVCLREIMKHDF", "length": 702, "header": "tr|E1BGT6-1|E1BGT6_BOVIN Isoform 1 of Pseudouridylate synthase PUS7L OS=Bos taurus OX=9913 GN=PUS7L PE=3 SV=2 CANONICAL=E1BGT6-1" }, "locus": { "chromosome": "5", "start_pos": 36729494, "end_pos": 36712242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045587.6", "url": "https://www.ensembl.org/id/ENSBTAT00000045587.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042966.3", "url": "https://www.ensembl.org/id/ENSBTAP00000042966.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505464", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505464", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X3V2-1", "protein_name": "Pseudouridylate synthase PUS7L", "gene_name": "PUS7L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGPGTADGRGKAVAAGRAAMLRSLSYVTDHTGFRGTIKKAPADFVVRELELPQRPAAPRDVSPPAGGPPAASATASAGAGSTVGPARCDPVTYPEQSRCAAGLKSGPEAAALLDSLLGKPASERLTKFACDLKEAWDSETGCDAGAGEFSLGAVVDKRDRADLHGAIRQRFPFLVTVTKDNEMVVKGNADYRELCQLVTEKETSDFFKFLDAKLENSTFSFEPDGNKEHRKIVHHFINKKFGKILETKSFTVADVGCEPNMSIIVRFRGRSCSRKRSADGFQIKQDLYTAFTLQKENLETLEAISFLAAELGVLPSDFSYSGIKDKKAITYQLMVVKKVTPERLKEIESKLEKKGMRIHNIHSAQQHLRLGQLRGNHFDIVVRDLKHHSHDSPVDLKERISEAMENIEAKGFVNYYGPQRFGQGQNVQTDQIGLALLNEKMVKAVKLFFTPEDTDDPVNNAKRYFLQTEDAKGTLTMLPEFKVREKMLLRALHRYGVNQEGCIKGWLSIPHSVRIFYVHAYCSQIWNEATSYRLKTYGSKVVEGDLVFSEENDESLSLNDKVHVVTALEESASKYSMHQVVLPMVGHSIKYPSNKVGQWYRERLSKDELQMCKFRVPPLQLNIPGCYRHILKNVQNLSYFLEGNEEGSKIEDNHLNESKVSLHISFDLDPSCYATVCLREIMKCDF", "length": 687 }, "evidence": [ { "id": "E1BGT6", "url": "https://omabrowser.org/oma/group/E1BGT6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LC41-1", "protein_name": "Pseudouridylate synthase PUS7L", "gene_name": "Pus7l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGYPWVQDWWTREEGVVVVAEEAGWGGSGGSLRILRSPCGAEEELLPPSSHVPAFAVCLFTSCLAARHLSCTVSTSSPESLPVDFVFLQSLGFRRPLWTWSELPLETPPRDRCQSLTGCSLPFLAPLIMEEDADDGIRSGSLCFINDHVGFQGSIKTSPGDFIVTEIDEQGRLVSKATDEPLREFSKTQPEPSNCQVKKPKLNTQTVDLDCENNKEAAKSPGHSPAGRSEGDRVQPAGSDRDSEKENSVRCATSKCEVESVGLLSSLLDESTHTSLDHFARDVKEMWNSSTELTEPSPELSLGRILDKRQRAALHSAVRQTFPFLITVGNNSEVVVKPSLEYKELSHLVSEEEALGFFRYLDAKKENSKFTFQPDPNKDHRKAVHHFLNKKFGNLVETKSFPGQSHSAGNPNTAITVRFREKAHGKRAHPEGKRRRAVYTAFTLQKENLEMFEAIGFLAIQLGVIPSDFSYAGLKDKKAITYQSMVVRKVTPERLKTIEEEIKKKRMNVFNVRSVDDSLRLGQLKGNHFEIIIRNLRNQPNDSANLRERVLEAIENVKNKGFVNYYGPQRFGKGKKIQTDRIGLALLKNEMVKAIKLFLTPEDADDPVNKAKKYFLQTEDAKGTLSLMPEFRVRERALLESLHRFGVTEEGCVQAWFSFPHSMRIFYIHAYSSRIWNEAASYRLAAYGPKVVKGDLVCLDEDADEHLPSSKVHLVTEEEESADTYALHQVVLPVLGYNVQYPENKVGRWYQGVLGRDGLQACRFRVPALKLNVPGCYRHIVKHPHNVSHRLVHPDPAELRAEGPHADDTASSLALSFDLDASCYATVCLREMMKDDI", "length": 838 }, "evidence": [ { "id": "E1BGT6", "url": "https://omabrowser.org/oma/group/E1BGT6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SGY7-1", "protein_name": "Pseudouridylate synthase PUS7L", "gene_name": "PUS7L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEEDTDFRIRFNSLCFITDHVGFHGTIKSSPSDFVVIEIDEQGQLVNKASDEHVYKVHKVLPEPNNLAKKPKLDLQNVSFEERSNQEVKTSAGCSDDDQNYEPASEKADTIKDGILRGEKEHLDVFGSLLDEKTNELLNQYAGDIKEKWNSKTELIGPSPEFSLGRILDKNQRATLHSAVRQKFPFLITVGKNSEIVVKPNLECKELCHLVSEEEAFGFFKYLDARKENSKFTFKSDTDKEHRKAVHHFVNKKFGNLVETKSFPELNYGADNPNVVITVRFREKAHKHKKRSLHECPERKVIHTAFTLRKENLEMFEAVGFLAIKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIEKELEKKRMNILNIRSVDDSLRLGQLKGNHFDIVIRNLKNQINDSTSLRERILEAIENVKNKGFVNYYGPQRFGMGRKVHTDQIGLALLKSEMVKAVKLFLTPEDSDDPVNRAKKYFLQTDDAKGTLSLMPEFKVRERALLESLHRFGMTEEGCVQAWFSFPHSMRIFYVHAYSSKIWNEAASYRLATYGSRVVEGDLVCLEEDVDDEHLPSSKVHLVTEEDESANTYAIHQVVLPVLGYNIQYPKNKVGQWYQEVLSRDGLQTCRFKIPPLKLNVPGCYRKILKHPHNLSYQLIEDADIDVKKDGSHIDEATVSLLISFDLDASCYATVCLREIMKHDF", "length": 702 }, "evidence": [ { "id": "E1BGT6", "url": "https://omabrowser.org/oma/group/E1BGT6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1L8I0-1", "protein_name": "Pseudouridylate synthase PUS7L", "gene_name": "pus7l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MERNTLSCFISDHEGFNGTIKNSPQDFVVIEIDTNGQFVNSVNTEEEERPCQTTKRIGKLKPSKPDDTDSLIQDCFDLNLILGLSVNRELEHFTNKLKVKPCSDDQEKVELSLGTFPDKHMRAVVHKAVRFNFPFLQTLTNQSEIRVREDPDFQELAGLASEGEAEDFFRFIDAKTPGSVFTFLPDDSKEHRTSVHHFVSRRFGKLVETKSFVDQQKTCITVRLRERGKQAKKRTMADCQMQEESLYTAFTLRKENLETLEAISYMAAVLGVLPSDFTYAGIKDKRAITYQAMVVKKISPERLLEKGSEFERRGMEISRVRPAFEALKLGRLQGNHFELVIRDLKHHGKHGLAELPKVIEEAVENVKNKGFVNYYGPQRFGSGSCVQADQVGLALLKENMEASVKLFFTPEDDDDLQNKAKRHFLHTGNAKESLVLMPAYKARERLMLRALHRYGSGQEGCTRGWLSLPHSMRVFYLHSYCSRVWNQAAKYRLQKLGFKPVQGDLVWAEPVKGLKDATEELSAPQIHVVTSDEEKNEVFSLDQVILPMPGNSVKYPENLLGQWYQDRLAQDGLESCRFRVTPLKLNVPGCYRPLLAKPQNITYSLQTSSSDESNTHCLSLNFDLEASCYATVCLGEIMKTNLS", "length": 643 }, "evidence": [ { "id": "E1BGT6", "url": "https://omabrowser.org/oma/group/E1BGT6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CE46-1", "protein_name": "Pseudouridylate synthase PUS7L", "gene_name": "Pus7l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEDTDGGIRFNSLCFINDHVGFQGSIKTSPSDFIVIEIDEQGQLVSKATDGSLYEISKIQSEPSNSVKKPKLNIQNVSLEHKNSEGAADLPGCSDGDRSHQSDSEKENSVNSVTSKCEEESVDLLRSLLDEKTHTSLGQFACDIKRMWNSQTELTEPSPELSLGKILDKNRRAVLHSAVRQAFPFLITVGNQGEVVVKPNRECKELCRLVSEEEALGFFKYLDAKKENSKFTFKPDPNKDHRKAVHHFLNKKFGNLVETKSFPGQHHSAGNPDSAITVRFREKARGKRSHPEGCERGKAVYTAFTLQKENLETFEAIGLLAVKLGVIPSDFSYAGLKDKRAITYQSMVVKKVTPERLKSIKEEIEKKRMNVFNIRSVGDCLRLGQLKGNHFEIIIRHLRNQLNDSANLTERILEAIENVKNKGFVNYYGPQRFGKGQKIQTDQIGLALLKNEMVKAIKLFLTPEDVDDPVNKAKQYFLRTEDAKGTLSLMPEFRVRERALLESLHRFGVTEEGCVRAWFSFPHSMRIFYIHAYSSRIWNEAASYRLAAYGPKVVEGDLICSDEDADKHFPSSKVHLVTKEEESAHTYALHQVVLPVLGYNVQYPENQVGRWYQEALSRDGLQACRFRVPALKLNVPGCYRHIVKHPRNVSHRLVHPDPATEEARVEGPHSDDTASSLSLSFDLDASCYATVCLREMMKGDI", "length": 702 }, "evidence": [ { "id": "E1BGT6", "url": "https://omabrowser.org/oma/group/E1BGT6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0K6-1", "protein_name": "Pseudouridylate synthase PUS7L", "gene_name": "PUS7L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDTDYRIRFSSLCFFNDHVGFHGTIKSSPSDFIVIEIDEQGQLVNKTIDEPIFKISEIQLEPNNFPKKPKLDLQNLSLEDGRNQEVHTLIKYTDGDQNHQSGSEKEDTIVDGTSKCEEKADVLSSFLDEKTHELLNNFACDVREKWLSKTELIGLPPEFSIGRILDKNQRASLHSAIRQKFPFLVTVGKNSEIVVKPNLEYKELCHLVSEEEAFDFFKYLDAKKENSKFTFKPDTNKDHRKAVHHFVNKKFGNLVETKSFSKMNCSAGNPNVVVTVRFREKAHKRGKRPLSECQEGKVIYTAFTLRKENLEMFEAIGFLAIKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIEKEIEKKRMNVFNIRSVDDSLRLGQLKGNHFDIVIRNLKKQINDSANLRERIMEAIENVKKKGFVNYYGPQRFGKGRKVHTDQIGLALLKNEMMKAIKLFLTPEDLDDPVNRAKKYFLQTEDAKGTLSLMPEFKVRERALLEALHRFGMTEEGCIQAWFSLPHSMRIFYVHAYTSKIWNEAVSYRLETYGARVVQGDLVCLDEDIDDENFPNSKIHLVTEEEGSANMYAIHQVVLPVLGYNIQYPKNKVGQWYHDILSRDGLQTCRFKVPTLKLNIPGCYRQILKHPCNLSYQLMEDHDIDVKTKGSHIDETALSLLISFDLDASCYATVCLKEIMKHDV", "length": 701 }, "evidence": [ { "id": "E1BGT6", "url": "https://omabrowser.org/oma/group/E1BGT6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BGT6", "url": "https://www.uniprot.org/uniprotkb/E1BGT6" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "E1BGT6", "url": "https://www.uniprot.org/uniprotkb/E1BGT6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BGT6", "url": "https://www.uniprot.org/uniprotkb/E1BGT6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "E1BGT6", "url": "https://www.uniprot.org/uniprotkb/E1BGT6" } ], "pmid": "" }, { "name": "pseudouridine synthesis", "id": "GO:0001522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001522", "evidence": [ { "database": "UniProtKB", "id": "E1BGT6", "url": "https://www.uniprot.org/uniprotkb/E1BGT6" } ], "pmid": "" }, { "name": "mRNA pseudouridine synthesis", "id": "GO:1990481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990481", "evidence": [ { "database": "UniProtKB", "id": "E1BGT6", "url": "https://www.uniprot.org/uniprotkb/E1BGT6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "56644", "name": "", "equation": "a uridine in mRNA = a pseudouridine in mRNA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08DI8-1", "Q5E9Z1-1", "Q2TBK7-1", "E1BDL3-1", "A0AAA9T9C6-1" ], "evidence": [ { "id": "56644", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56644" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9T9C6", "gene_name": "TRUB1", "activity": [ { "ec_number": "5.4.99.25", "activity": "uridine(55) in tRNA = pseudouridine(55) in tRNA.", "evidence": [ { "id": "A0AAA9T9C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9C6" } ] }, { "ec_number": "5.4.99.25", "activity": "", "evidence": [ { "id": "A0AAA9T9C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9C6" } ] } ] }, { "uniprot_ac": "E1BDL3", "gene_name": "PUS1", "activity": [ { "ec_number": "5.4.99.12", "activity": "uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA.", "evidence": [ { "id": "E1BDL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDL3" } ] }, { "ec_number": "5.4.99.12", "activity": "", "evidence": [ { "id": "E1BDL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDL3" } ] } ] }, { "uniprot_ac": "Q08DI8", "gene_name": "PUS7", "activity": [ { "ec_number": "5.4.99.-", "activity": "", "evidence": [ { "id": "Q08DI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DI8" } ] } ] }, { "uniprot_ac": "Q2TBK7", "gene_name": "RPUSD3", "activity": [ { "ec_number": "5.4.99.-", "activity": "", "evidence": [ { "id": "Q2TBK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBK7" } ] } ] }, { "uniprot_ac": "Q5E9Z1", "gene_name": "RPUSD4", "activity": [ { "ec_number": "5.4.99.-", "activity": "", "evidence": [ { "id": "Q5E9Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Z1" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGT6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 702, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGT6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGT6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGT6" }, { "id": "PS50984", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50984" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRUD", "eco_id": "ECO_0000259", "start_pos": 425, "end_pos": 648, "start_aa": "Gly", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 267, "end_pos": 269 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 651, "end_pos": 653 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGU0-1", "uniprot_ac": "E1BGU0", "uniprot_id": "E1BGU0_BOVIN", "mass": { "chemical_mass": 221712.0, "monoisotopic_mass": 221712.0 }, "refseq": {}, "gene_names": [ { "name": "HEATR5A", "type": "recommended", "evidence": [ { "id": "E1BGU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGU0" } ] } ], "protein_names": [ { "name": "HEAT repeat-containing protein 5A", "type": "recommended", "evidence": [ { "id": "E1BGU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGU0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGU0", "url": "https://www.uniprot.org/uniprotkb/E1BGU0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HEATR5A", "url": "https://www.uniprot.org/uniprotkb/E1BGU0", "locus": { "chromosome": "21", "start_pos": 41835288, "end_pos": 41932944, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000022847", "url": "https://www.ensembl.org/id/ENSBTAG00000022847" } ] } } ], "crossref": [ { "id": "ENSBTAG00000022847", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000022847", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3N2J2", "url": "https://www.orthodb.org/?gene=G3N2J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21663:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21663:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25468", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25468", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BGU0", "url": "https://www.uniprot.org/uniprotkb/E1BGU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGU0-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2J2", "url": "https://www.uniprot.org/uniprotkb/G3N2J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2J2-1", "url": "https://www.uniprot.org/uniprotkb/G3N2J2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELAHSLLLNEEAYSQLGEVQKAEFIFDWLRYLEKLLVATSRSDVREKQKTLVEQLLSLLNSSPGPPTRKLLAKNLALLYSIGDTFSVYETIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILGNTFTDTVGNILKAMKSAESQGRYEIMLSLQNILNGLGAAAIPCHRDVYKAARSCLTDRSMAVRCAAAKCLLELQNEAVFMWSTDLDSVATLCFKSFEGSNYDVRISVSKLLGTVLAKAIISKHPGTASRQSIRRVSLEEVLELLGTGFLRGSSGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFISTLGGAWLEKNFAAFLSHILSLVSQSHPKATQTQIDAVCSRRCVSFILRATVGGLLGEKAQIAAAKDICQAIWKLKKIMDAVMSDGNLETRLGSADVAASQHMLVCALQELGNLIHSLGTTAAPLLQDSSAGILDNVISVTLHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTVLKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKIIMALAEDLLCSAAQNSRLSAQRTQAGWLLIAALMTLGPAFVSHHLARVLLLWKCVFPVSPKDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVAHCGDLLTEEVIQHLLPPLPCTVDLLTQLSSILKTYGSPLKTPSVVYRQRLYELLILLSPETYEGNLSVILRELAADLTAPDIQVAASAFLLPPLCHQDDLLILSPLLQETDHRFIEEQLLLGSGIACGSLEYDPYSIYEKDVEGDSVPKPLPPMLSVTSSAVKLFGVVCAHVGEAQRLLVLEQLLDSVKHTKGARQQVVQLHVVSSVSSFLKYVAGSKGHLGPEEVRRPVLALVMGALESPSPLLRCAAAEAWARLAQVVDDGAFTAALAQVSFDKLKSARDAVTRTGHSLALGSLHRYLGGISSQHLNSCVGILYTLSQDSTSPDVQTWALHSLSLIIDSAGPLYYTHAEPTLSLIMMLLLNVPSTHAEVHQSLGRCLNALITTLGPELQGNSTSVSTLRSSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLLRRAVLACLCQLVQREAAEVSEHAVMLAKNSREELTLDANIREVGLEGALLTLLDKETDQKLCHDIKETLNHMLTSMAVDKLSFWLKLCKDVLAASADFASVTCVDTMQEEEGDKGDDASVLTNRNDGRPHPFTNPRWATRVFAAECVCRIINQCENGHSAHFDVALAQEMKKKDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLETLLVVIRRFAAIPEPEFPGHVILEQYQANVGAALRPAFTSETPPDVTAKACQVCSAWIASGVVSDLNDIRRVHQLLVASLTKIQVGKEALSHLYNESASTMEILAVLKAWAEVYIIAVERHKNHRQSLKTPACSEESVGNGSISPDGLLDLVHADLGTLSRLWLAALQDFALLTLPSEFASQLPVEGGAFYTAETSENAKLHYYNSWALILHATALWLTSTGFVVADPDEGAPNLSRPVTPTSMCQGSSSGPTVKSPEDVYTERFHLILGISVKFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELLNVLHRVILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPGLNPKLTGSPGVKAAKPQMLSEDGSRLVSAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSPMARAEKSHTAWTDLLRSALTTILDCWDPVDGTHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIEKFKATLEIKDPMVQIKTYQLLLSIFQYPNPAVSYPYIYSLVSSIVEKLQEINRRKPEDTAELQIFQEGIKVLEALVAVAEEQHRSQLVACLLPILISFVLDEHALGSATSIMRNLHDFALQNLMQIGPQYSSVFKSVMASSPALKARLEAAIKGNQETVKVKTPTSKHTKNSGKSSSIQLKTNFL", "length": 2044, "header": "tr|E1BGU0-1|E1BGU0_BOVIN Isoform 1 of HEAT repeat-containing protein 5A OS=Bos taurus OX=9913 GN=HEATR5A PE=3 SV=3 CANONICAL=E1BGU0-1" }, "isoforms": [ { "isoform_ac": "E1BGU0-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU0/entry#E1BGU0-1", "sequence": { "sequence": "MELAHSLLLNEEAYSQLGEVQKAEFIFDWLRYLEKLLVATSRSDVREKQKTLVEQLLSLLNSSPGPPTRKLLAKNLALLYSIGDTFSVYETIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILGNTFTDTVGNILKAMKSAESQGRYEIMLSLQNILNGLGAAAIPCHRDVYKAARSCLTDRSMAVRCAAAKCLLELQNEAVFMWSTDLDSVATLCFKSFEGSNYDVRISVSKLLGTVLAKAIISKHPGTASRQSIRRVSLEEVLELLGTGFLRGSSGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFISTLGGAWLEKNFAAFLSHILSLVSQSHPKATQTQIDAVCSRRCVSFILRATVGGLLGEKAQIAAAKDICQAIWKLKKIMDAVMSDGNLETRLGSADVAASQHMLVCALQELGNLIHSLGTTAAPLLQDSSAGILDNVISVTLHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTVLKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKIIMALAEDLLCSAAQNSRLSAQRTQAGWLLIAALMTLGPAFVSHHLARVLLLWKCVFPVSPKDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVAHCGDLLTEEVIQHLLPPLPCTVDLLTQLSSILKTYGSPLKTPSVVYRQRLYELLILLSPETYEGNLSVILRELAADLTAPDIQVAASAFLLPPLCHQDDLLILSPLLQETDHRFIEEQLLLGSGIACGSLEYDPYSIYEKDVEGDSVPKPLPPMLSVTSSAVKLFGVVCAHVGEAQRLLVLEQLLDSVKHTKGARQQVVQLHVVSSVSSFLKYVAGSKGHLGPEEVRRPVLALVMGALESPSPLLRCAAAEAWARLAQVVDDGAFTAALAQVSFDKLKSARDAVTRTGHSLALGSLHRYLGGISSQHLNSCVGILYTLSQDSTSPDVQTWALHSLSLIIDSAGPLYYTHAEPTLSLIMMLLLNVPSTHAEVHQSLGRCLNALITTLGPELQGNSTSVSTLRSSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLLRRAVLACLCQLVQREAAEVSEHAVMLAKNSREELTLDANIREVGLEGALLTLLDKETDQKLCHDIKETLNHMLTSMAVDKLSFWLKLCKDVLAASADFASVTCVDTMQEEEGDKGDDASVLTNRNDGRPHPFTNPRWATRVFAAECVCRIINQCENGHSAHFDVALAQEMKKKDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLETLLVVIRRFAAIPEPEFPGHVILEQYQANVGAALRPAFTSETPPDVTAKACQVCSAWIASGVVSDLNDIRRVHQLLVASLTKIQVGKEALSHLYNESASTMEILAVLKAWAEVYIIAVERHKNHRQSLKTPACSEESVGNGSISPDGLLDLVHADLGTLSRLWLAALQDFALLTLPSEFASQLPVEGGAFYTAETSENAKLHYYNSWALILHATALWLTSTGFVVADPDEGAPNLSRPVTPTSMCQGSSSGPTVKSPEDVYTERFHLILGISVKFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELLNVLHRVILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPGLNPKLTGSPGVKAAKPQMLSEDGSRLVSAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSPMARAEKSHTAWTDLLRSALTTILDCWDPVDGTHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIEKFKATLEIKDPMVQIKTYQLLLSIFQYPNPAVSYPYIYSLVSSIVEKLQEINRRKPEDTAELQIFQEGIKVLEALVAVAEEQHRSQLVACLLPILISFVLDEHALGSATSIMRNLHDFALQNLMQIGPQYSSVFKSVMASSPALKARLEAAIKGNQETVKVKTPTSKHTKNSGKSSSIQLKTNFL", "length": 2044, "header": "tr|E1BGU0-1|E1BGU0_BOVIN Isoform 1 of HEAT repeat-containing protein 5A OS=Bos taurus OX=9913 GN=HEATR5A PE=3 SV=3 CANONICAL=E1BGU0-1" }, "locus": { "chromosome": "21", "start_pos": 41918460, "end_pos": 41836292, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031031.6", "url": "https://www.ensembl.org/id/ENSBTAT00000031031.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030995.6", "url": "https://www.ensembl.org/id/ENSBTAP00000030995.6" } ] } }, { "isoform_ac": "G3N2J2-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU0/entry#G3N2J2-1", "sequence": { "sequence": "MELAHSLLLNEEAYSQLGEVQKAEFIFDWLRYLEKLLVATSRSDVREKQKTLVEQLLSLLNSSPGPPTRKLLAKNLALLYSIGDTFSVYETIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILGNTFTDTVGNILKAMKSAESQGRYEIMLSLQNILNGLGAAAIPCHRDVYKAARSCLTDRSMAVRCAAAKCLLELQNEAVFMWSTDLDSVATLCFKSFEGSNYDVRISVSKLLGTVLAKAIISKHPGTAASRQSIRRVSLEEVLELLGTGFLRGSSGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFISTLGGAWLEKNFAAFLSHILSLVSQSHPKATQTQIDAVCSRRCVSFILRATVGGLLGEKAQIAAAKDICQAIWKLKKIMDAVMSDGNLETRLGSADVAASQHMLVCALQELGNLIHSLGTTAAPLLQDSSAGILDNVISVTLHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTVLKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKIIMALAEDLLCSAAQNSRLSAQRTQAGWLLIAALMTLGPAFVSHHLARVLLLWKCVFPVSPKDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVAHCGDLLTEEVIQHLLPPLPCTVDLLTQLSSILKTYGSPLKTPSVVYRQRLYELLILLSPETYEGNLSVILRELAADLTAPDIQVAASAFLLPPLCHQDDLLILSPLLQETDHRFIEEQLLLGSGIACGSLEYDPYSIYEKDVEGDSVPKPLPPMLSVTSSAVKLFGVVCAHVGEAQRLLVLEQLLDSVKHTKGARQQVVQLHVVSSVSSFLKYVAGSKGHLGPEEVRRPVLALVMGALESPSPLLRCAAAEAWARLAQVVDDGAFTAALAQVSFDKLKSARDAVTRTGHSLALGSLHRYLGGISSQHLNSCVGILYTLSQDSTSPDVQTWALHSLSLIIDSAGPLYYTHAEPTLSLIMMLLLNVPSTHAEVHQSLGRCLNALITTLGPELQGNSTSVSTLRSSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLLRRAVLACLCQLVQREAAEVSEHAVMLAKNSREELTLDANIREVGLEGALLTLLDKETDQKLCHDIKETLNHMLTSMAVDKLSFWLKLCKDVLAASADFASVTCVDTMQEEEGDKGDDASVLTNRNDGRPHPFTNPRWATRVFAAECVCRIINQCENGHSAHFDVALAQEMKKKDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLETLLVVIRRFAAIPEPEFPGHVILEQYQANVGAALRPAFTSETPPDVTAKACQVCSAWIASGVVSDLNDIRRVHQLLVASLTKIQVGKEALSHLYNESASTMEILAVLKAWAEVYIIAVERHKNHRQSLKTPACSEESVGNGSISPDGLLDLVHADLGTLSRLWLAALQDFALLTLPSEFASQLPVEGGAFYTAETSENAKLHYYNSWALILHATALWLTSTGFVVADPDEGAPNLSRPVTPTSMCQGSSSGPTVKSPEDVYTERFHLILGISVKFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELLNVLHRVILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPGLNPKLTGSPGVKAAKPQMLSEDGSRLVSAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSPMARAEKSHTAWTDLLRSALTTILDCWDPDGTHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIEKFKATLEIKDPMVQIKTYQLLLSIFQYPNPAVSYPYIYSLVSSIVEKLQEINRRKPEDTAELQIFQEGIKVLEALVAVAEEQHRKC", "length": 1945, "header": "tr|G3N2J2-1|E1BGU0_BOVIN Computationally mapped isoform of HEAT repeat-containing protein 5A OS=Bos taurus OX=9913 GN=HEATR5A PE=3 SV=3 CANONICAL=E1BGU0-1" }, "locus": { "chromosome": "21", "start_pos": 41918460, "end_pos": 41836865, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065848.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065848.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056107.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056107.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BGU0", "url": "https://www.uniprot.org/uniprotkb/E1BGU0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BGU0", "url": "https://www.uniprot.org/uniprotkb/E1BGU0" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "E1BGU0", "url": "https://www.uniprot.org/uniprotkb/E1BGU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "E1BGU0", "url": "https://www.uniprot.org/uniprotkb/E1BGU0" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "E1BGU0", "url": "https://www.uniprot.org/uniprotkb/E1BGU0" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "E1BGU0", "url": "https://www.uniprot.org/uniprotkb/E1BGU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1019, "end_pos": 1021, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1065, "end_pos": 1067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1387, "end_pos": 1389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1432, "end_pos": 1434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1526, "end_pos": 1528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 691, "end_pos": 693, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1019, "end_pos": 1021 }, { "start_pos": 1065, "end_pos": 1067 }, { "start_pos": 1387, "end_pos": 1389 }, { "start_pos": 1432, "end_pos": 1434 }, { "start_pos": 1526, "end_pos": 1528 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 691, "end_pos": 693 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGU5-1", "uniprot_ac": "E1BGU5", "uniprot_id": "E1BGU5_BOVIN", "mass": { "chemical_mass": 103573.0, "monoisotopic_mass": 103573.0 }, "refseq": { "ac": "XP_010806690", "name": "microtubule cross-linking factor 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806690" }, "gene_names": [ { "name": "MTCL3", "type": "recommended", "evidence": [ { "id": "E1BGU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGU5" } ] }, { "name": "MTCL3", "type": "synonym", "evidence": [ { "id": "XP_010806690", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806690" } ] } ], "protein_names": [ { "name": "MTCL family member 3", "type": "synonym", "evidence": [ { "id": "E1BGU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGU5/entry#names_and_taxonomy" } ] }, { "name": "microtubule cross-linking factor 3", "type": "synonym", "evidence": [ { "id": "XP_010806690", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806690" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGU5", "url": "https://www.uniprot.org/uniprotkb/E1BGU5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MTCL3", "url": "https://www.uniprot.org/uniprotkb/E1BGU5", "locus": { "chromosome": "9", "start_pos": 23829939, "end_pos": 23784274, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003921", "url": "https://www.ensembl.org/id/ENSBTAG00000003921" } ] } } ], "crossref": [ { "id": "E1BGU5", "url": "https://alphafold.ebi.ac.uk/entry/E1BGU5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003921", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003921", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "535392", "url": "https://www.ncbi.nlm.nih.gov/gene/535392", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:535392", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535392", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HMIDIRI", "url": "https://omabrowser.org/oma/group/HMIDIRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGU5", "url": "https://www.orthodb.org/?gene=E1BGU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15742:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15742:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010806690", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806690", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BGU5", "url": "https://www.uniprot.org/uniprotkb/E1BGU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGU5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQPPTGGAAPLTAAAPAATGATEARLHPEGSSRKQQRAQSPARLRDNSVRQATATTRAPVGAGTKLNSSRQQQLQQQQGNKTGSRSAPPASARGSGGGAEKAAPPAPKGAASGAVQPVAGAEAALVATVAPVGVRRPGLSEEPLRELEPASSKLGEPPPLGEGGGGGGEGGGAVSGSGEREGGAPLPPPPPRGWRGKSVRAQQRGGSGGEGASPSLSSSSSAGKTPGPGSRNSGLGVVAGGGGAGGSYWKEGCLQSELIQFHLKKERAAAAAAAQMHAKNGGGSSSSHRSSPVAGAPAVCEPLAVPPASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNGSANPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSGGHESARHHDSAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRCLTPTRSFYPAPPPGPWPKSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDPGAEEPISVSQMFQPIILLILILVLFSSLSYTTIFKLVFLFTLFFVL", "length": 950, "header": "tr|E1BGU5-1|E1BGU5_BOVIN Isoform 1 of MTCL family member 3 OS=Bos taurus OX=9913 GN=MTCL3 PE=4 SV=1 CANONICAL=E1BGU5-1" }, "isoforms": [ { "isoform_ac": "E1BGU5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU5/entry#E1BGU5-1", "sequence": { "sequence": "MSQPPTGGAAPLTAAAPAATGATEARLHPEGSSRKQQRAQSPARLRDNSVRQATATTRAPVGAGTKLNSSRQQQLQQQQGNKTGSRSAPPASARGSGGGAEKAAPPAPKGAASGAVQPVAGAEAALVATVAPVGVRRPGLSEEPLRELEPASSKLGEPPPLGEGGGGGGEGGGAVSGSGEREGGAPLPPPPPRGWRGKSVRAQQRGGSGGEGASPSLSSSSSAGKTPGPGSRNSGLGVVAGGGGAGGSYWKEGCLQSELIQFHLKKERAAAAAAAQMHAKNGGGSSSSHRSSPVAGAPAVCEPLAVPPASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNGSANPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSGGHESARHHDSAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRCLTPTRSFYPAPPPGPWPKSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDPGAEEPISVSQMFQPIILLILILVLFSSLSYTTIFKLVFLFTLFFVL", "length": 950, "header": "tr|E1BGU5-1|E1BGU5_BOVIN Isoform 1 of MTCL family member 3 OS=Bos taurus OX=9913 GN=MTCL3 PE=4 SV=1 CANONICAL=E1BGU5-1" }, "locus": { "chromosome": "9", "start_pos": 23829742, "end_pos": 23784274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005118.5", "url": "https://www.ensembl.org/id/ENSBTAT00000005118.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005118.3", "url": "https://www.ensembl.org/id/ENSBTAP00000005118.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:535392", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535392", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L8H3-1", "protein_name": "MTCL family member 3", "gene_name": "Mtcl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQPPSGGAAPAATSASAAAAATEARMHPEGSSRKQQRAQSPARPRDNSLRQAAGAARSPLGVGPKLNSVRQQQLLQQQQQGNKTTGRGASGAGSRGYGGGAEKAAPSLPKGAAPGAVQPAPGAEGSPAAIPGAVSCRRSGLPVEPPQEIESGPSKVGEPPPLGGGGGGGEGGGAGGGPGDREGGAPQPPPPRGWRGKGVRASQRGISGEGVSPSPPTAATSRTPGPGSRNSGSGGTGGGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHTKNGGGGSRNSPVAGAPAICEPLVVPSFSPMAAAAEGPQQSAEGSSSAGAMQAAAPPSTQPHSQQLQEQEDMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEDDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNGSSNPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSSGHDSSRHHDSAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRSLTPTRSFYPTPGPWPKSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDHGAEEPISVSQVQFCLLRAMAMARLARGAAVPRGASPTPTSTSHFREVPSQGLAVLKAPVFSQHVPPGRGSRSSTDH", "length": 974 }, "evidence": [ { "id": "E1BGU5", "url": "https://omabrowser.org/oma/group/E1BGU5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S2X4-1", "protein_name": "MTCL family member 3", "gene_name": "MTCL3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSQPPTGGAAPATAAASAATAATEARLHPEGSSRKQQRAQSPARLRDNSVRQTTATTRSPVGAGTKVNSVRQQQLQQQQQGNKTGSRSAPPASARGSGGGAEKAAPLAPKGAAPGAVQTVAGAEAAPVATLAPAGVRRPGPSEETPRELDPASSKLGEPPPLGEGGGGGGEGGGAGSGSGEREGGAPQPPPPPRGWRGKSVRAQQRGGSGGEGAAPSPSSSSAGKTLGPGSRNSGIGVVGGGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHTKNGGGGSNRSSPVAGAPSICEPLAVPFNSSMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNGSANPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSGSHESSRHHDNAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRCLTPTRSFYPAPGPWPKSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDQGAEEPISVSQMFQPIILLILILVLFSSLSYTTIFKLVFLFTLFFVL", "length": 947 }, "evidence": [ { "id": "E1BGU5", "url": "https://omabrowser.org/oma/group/E1BGU5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5TF21-1", "protein_name": "Microtubule cross-linking factor 3", "gene_name": "MTCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQPPIGGAAPATAAASPAAAATEARLHPEGSSRKQQRAQSPARPRDSSLRQTIAATRSPVGAGTKLNSVRQQQLQQQQQQGNKTGSRTGPPASIRGGGGGAEKATPLAPKGAAPGAVQPVAGAEAAPAATLAALGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGGGGGEGGGAGGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHAKNGGGSSSRSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNGSANPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSGGHDSARHHDNAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRCLTPTRSFYPAPGPWPKSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDRGAEEPISVSQMFQPIILLILILVLFSSLSYTTIFKLVFLFTLFFVL", "length": 947 }, "evidence": [ { "id": "E1BGU5", "url": "https://omabrowser.org/oma/group/E1BGU5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NZL0-1", "protein_name": "Microtubule cross-linking factor 3", "gene_name": "Mtcl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQPPSGGAAPAATSASAAAAATEARMHPEGCSRKQQRAQSPARPRDNSLRQTAGATRSPLGVGPKLNSVRQQQLQQQQQQGNKITGRSTSGTGSRGLGGGAEKAVPSIPKGAVPGAVQPAPGAEGSPAAILASVSFRRSGQPEEAPREIESGPSKVGEPPPLGGVGGGGEGGGAGGGPGDREGGAPQPPPPRGWRGKGVRATQRGSSVAEGVSPSPPTAATSKTPGPGSRNSGSGSTGSGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHTKNGGGGSRSSPVAGAPAICEPLVVPSSSPMAAAAEGPQQSAEGNGSGGAMQAAAPPSSQPHSQQLQEQEDMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEDDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGEDFNGSSNPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSSGHDSSRHHDNAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRSLTPTRSFYPTPGPWPKSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDRGAEEPISVSQMFQPIILLILILVLFSSLSYTTIFKLVFLFTLFFVL", "length": 945 }, "evidence": [ { "id": "E1BGU5", "url": "https://omabrowser.org/oma/group/E1BGU5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BGU5", "url": "https://www.uniprot.org/uniprotkb/E1BGU5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BGU5", "url": "https://www.uniprot.org/uniprotkb/E1BGU5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "E1BGU5", "url": "https://www.uniprot.org/uniprotkb/E1BGU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGU5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 950, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGU5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGU5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGU5" }, { "id": "PF11365", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11365" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SOGA coiled-coil", "eco_id": "ECO_0000259", "start_pos": 522, "end_pos": 616, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 364, "end_pos": 366 }, { "start_pos": 629, "end_pos": 631 }, { "start_pos": 68, "end_pos": 70 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGU6-1", "uniprot_ac": "E1BGU6", "uniprot_id": "E1BGU6_BOVIN", "mass": { "chemical_mass": 61934.0, "monoisotopic_mass": 61934.0 }, "refseq": { "ac": "NP_001179406", "name": "cation channel sperm-associated protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179406" }, "gene_names": [ { "name": "CATSPER2", "type": "recommended", "evidence": [ { "id": "E1BGU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGU6" } ] }, { "name": "CATSPER2", "type": "synonym", "evidence": [ { "id": "NP_001179406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179406" } ] } ], "protein_names": [ { "name": "Cation channel sperm-associated protein 2", "type": "recommended", "evidence": [ { "id": "E1BGU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGU6/entry#names_and_taxonomy" } ] }, { "name": "cation channel sperm-associated protein 2", "type": "synonym", "evidence": [ { "id": "NP_001179406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179406" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGU6", "url": "https://www.uniprot.org/uniprotkb/E1BGU6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CATSPER2", "url": "https://www.uniprot.org/uniprotkb/E1BGU6", "locus": { "chromosome": "21", "start_pos": 55352680, "end_pos": 55370789, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000032130", "url": "https://www.ensembl.org/id/ENSBTAG00000032130" } ] } } ], "crossref": [ { "id": "E1BGU6", "url": "https://alphafold.ebi.ac.uk/entry/E1BGU6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000032130", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000032130", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "517699", "url": "https://www.ncbi.nlm.nih.gov/gene/517699", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:517699", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517699", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVVWPRD", "url": "https://omabrowser.org/oma/group/QVVWPRD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGU6", "url": "https://www.orthodb.org/?gene=E1BGU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46923", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46923", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46923:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46923:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1300642", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1300642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179406", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179406", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BGU6", "url": "https://www.uniprot.org/uniprotkb/E1BGU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGU6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATYHPSGHMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIREILDSSRQKKLMLGDQHQLVRFSIKPRHVERITHAQRLMSTLRVRCSERPPLSLWAGWVLERPIFRNFIIFLIFLNTVVLMVEIELLESANTQLEPLKLTLEVAAWFILLIFILEILLMWLSSFFLFWKNAWNVFDFVVTVLSLIPEIVVLAGVTSKPVWLQLLRICRVLRSLKLFARFHQVRVIILALVRALKSMTFLLMLLLIFFYIFAVAGVYFFENYTRSTRQDLEYHEFFSDLLNSIVTVFILFTLDHWYALLQDTWKVPEVSRTFSSIYVILWLLLGSIIFRNIIVAMMVTNFQNIRNELNEEMTHLEVQHKADIFKRQIIQRRQNLIPEAQRSSISKLDARDASQQGRPSDLTESSQQESKQSATRKGSKVSKSRTKSLSKRRKSTSSFSSSSSSFSSCSSVSSSRYCDLIGQLDWETHVHQNLPGLMDMDQDERVVWPRDSLFRYFELLEKLQYNLEERKQLQEFAVQALMNFEDK", "length": 529, "header": "tr|E1BGU6-1|E1BGU6_BOVIN Isoform 1 of Cation channel sperm-associated protein 2 OS=Bos taurus OX=9913 GN=CATSPER2 PE=3 SV=2 CANONICAL=E1BGU6-1" }, "isoforms": [ { "isoform_ac": "E1BGU6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGU6/entry#E1BGU6-1", "sequence": { "sequence": "MATYHPSGHMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIREILDSSRQKKLMLGDQHQLVRFSIKPRHVERITHAQRLMSTLRVRCSERPPLSLWAGWVLERPIFRNFIIFLIFLNTVVLMVEIELLESANTQLEPLKLTLEVAAWFILLIFILEILLMWLSSFFLFWKNAWNVFDFVVTVLSLIPEIVVLAGVTSKPVWLQLLRICRVLRSLKLFARFHQVRVIILALVRALKSMTFLLMLLLIFFYIFAVAGVYFFENYTRSTRQDLEYHEFFSDLLNSIVTVFILFTLDHWYALLQDTWKVPEVSRTFSSIYVILWLLLGSIIFRNIIVAMMVTNFQNIRNELNEEMTHLEVQHKADIFKRQIIQRRQNLIPEAQRSSISKLDARDASQQGRPSDLTESSQQESKQSATRKGSKVSKSRTKSLSKRRKSTSSFSSSSSSFSSCSSVSSSRYCDLIGQLDWETHVHQNLPGLMDMDQDERVVWPRDSLFRYFELLEKLQYNLEERKQLQEFAVQALMNFEDK", "length": 529, "header": "tr|E1BGU6-1|E1BGU6_BOVIN Isoform 1 of Cation channel sperm-associated protein 2 OS=Bos taurus OX=9913 GN=CATSPER2 PE=3 SV=2 CANONICAL=E1BGU6-1" }, "locus": { "chromosome": "21", "start_pos": 55369341, "end_pos": 55352683, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045580.4", "url": "https://www.ensembl.org/id/ENSBTAT00000045580.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042959.3", "url": "https://www.ensembl.org/id/ENSBTAP00000042959.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:517699", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517699", "resource": "KEGG Pathway" }, { "id": "R-BTA-1300642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1300642", "resource": "Reactome", "description": "Sperm Motility And Taxes" } ], "orthologs": [ { "uniprot_canonical_ac": "A2ARP9-1", "protein_name": "Cation channel sperm-associated protein 2", "gene_name": "Catsper2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQEQGHFQLLRADAIRSKLIDTFSLIEHLQGLSQAVPRHTLREILDPSYQQKLMSGDQEQLVRFSIKPRRMGHITHSRRLLSRLRVRCSRMPPLSLWAGWVLDSSVFSKFIISLIFLNTFVLMVEIELMESTNTALWPVKLALEVADWFILLSFIVEILLMWLASFSLFWKDAWNVFDFFVTLLSLLPELVVLLGVPAHSVWLQLLRVCRVLRSLKLFARFRQIKVILLALVRALKSMTFLLMLLLIFFYIFAVTGVYFFREYSRSTIEGLEYNMFFSDLLNSLVTVFILFTLDHWYAVLQDIWKVPESSRVFSSIYVILWLLLGSIIFRNIIVAMMVTNFQNIRSELSEEMSHLEVQYKADMFKQQIIQRRQHSESLRGTSLGKVSEDIIETSDASDDDDDDDDDDDDDDDDDDDKSDATESDNEESDSENSESENSESEKIDPEKDYAKKSYPEKSHPEKSYPEKSHPEKSYPEKSHPKKSYDEQAEAEKVKEESKEKAYPVSHSISSHGSTAADTAFLENLDWETLVHENLPGLMDMDQDDRIVWPRDSLFRYFELLEKLQYNLEERKKLQEFAVQALMSFEDK", "length": 588 }, "evidence": [ { "id": "E1BGU6", "url": "https://omabrowser.org/oma/group/E1BGU6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AXP6-1", "protein_name": "Cation channel sperm-associated protein 2", "gene_name": "Catsper2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHERGHLQLPRADAIRSKLIDTFSLIEHLQGLSQAVPRHTLREILDPACQKKLMLGDQEQLVRFSIRARRMGHITHAQRLLSRLRVRCGGRPPLSLWAGWVLDSSIFSNFIISLIFLNTFVLMVEIELMNSTNTSLWPLKLALEVTDWFILLSFIVEILLMWLASFFLFWKNAWSVFDFVVTMLSLLPEFVVLIGVSADSVWLQLLRVSRVLRSLKLFARFPQIKVILLALVRALKSMTFLLMLLLIFFYVFAVAGVYFFKEYSRSTIENLEYNMFFSDLLNSLVTVFILFTLDHWYAVLQDVWKVPEASRVFSSIYVILWLLLGSIIFRNIIVAMMVTNFQNIRNELHEEMTHLEVQYKADIFKRRIIQRRQQSESLRGTSQGKVSEDITETSEATDEEKSEAEESEEEKSEEEKSDVEKSDEEKNDEEKSDEEENDEEKSDVEKSDEEKNDEEKGYTEKVYSGRTFVERSYAERSFAGKAENEKVQKELKEKAYPGSPPNSSSHDEAFAADDTYLENLDWETLVHENLPGLMDMDQDDRVVWPRDSLFRYFELLESLQYNLEERKRLQEFAVQALMNFEDK", "length": 584 }, "evidence": [ { "id": "E1BGU6", "url": "https://omabrowser.org/oma/group/E1BGU6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96P56-1", "protein_name": "Cation channel sperm-associated protein 2", "gene_name": "CATSPER2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAYQQEEQMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVLGDQHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRPPLSLWAGWVLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVFDFVVTMLSLLPEVVVLVGVTGQSVWLQLLRICRVLRSLKLLAQFRQIQIIILVLVRALKSMTFLLMLLLIFFYIFAVTGVYVFSEYTRSPRQDLEYHVFFSDLPNSLVTVFILFTLDHWYALLQDVWKVPEVSRIFSSIYFILWLLLGSIIFRSIIVAMMVTNFQNIRKELNEEMARREVQLKADMFKRQIIQRRKNMSHEALTSSHSKIEDSSRGASQQRESLDLSEVSEVESNYGATEEDLITSASKTEETLSKKREYQSSSCVSSTSSSYSSSSESRFSESIGRLDWETLVHENLPGLMEMDQDDRVWPRDSLFRYFELLEKLQYNLEERKKLQEFAVQALMNLEDK", "length": 530 }, "evidence": [ { "id": "E1BGU6", "url": "https://omabrowser.org/oma/group/E1BGU6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "CatSper complex", "id": "GO:0036128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036128", "evidence": [ { "database": "UniProtKB", "id": "E1BGU6", "url": "https://www.uniprot.org/uniprotkb/E1BGU6" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "E1BGU6", "url": "https://www.uniprot.org/uniprotkb/E1BGU6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "E1BGU6", "url": "https://www.uniprot.org/uniprotkb/E1BGU6" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "E1BGU6", "url": "https://www.uniprot.org/uniprotkb/E1BGU6" } ], "pmid": "" }, { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "E1BGU6", "url": "https://www.uniprot.org/uniprotkb/E1BGU6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium-activated cation channel activity", "id": "GO:0005227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005227", "evidence": [ { "database": "UniProtKB", "id": "E1BGU6", "url": "https://www.uniprot.org/uniprotkb/E1BGU6" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "E1BGU6", "url": "https://www.uniprot.org/uniprotkb/E1BGU6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MPF0-1", "A0AAA9RSQ6-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGU6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 529, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGU6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGU6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGU6" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 108, "end_pos": 350, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGV9-1", "uniprot_ac": "E1BGV9", "uniprot_id": "E1BGV9_BOVIN", "mass": { "chemical_mass": 36758.0, "monoisotopic_mass": 36758.0 }, "refseq": { "ac": "NP_001377415", "name": "olfactory receptor family 10 subfamily AG member 75", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377415" }, "gene_names": [ { "name": "OR10AG75", "type": "recommended", "evidence": [ { "id": "E1BGV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV9" } ] }, { "name": "OR10AG75", "type": "synonym", "evidence": [ { "id": "NP_001377415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377415" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BGV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 10AG1", "type": "synonym", "evidence": [ { "id": "NP_001377415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377415" } ] }, { "name": "olfactory receptor family 10 subfamily AG member 75", "type": "synonym", "evidence": [ { "id": "NP_001377415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377415" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377415", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377415" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BGV9", "url": "https://www.uniprot.org/uniprotkb/E1BGV9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGV9", "url": "https://www.uniprot.org/uniprotkb/E1BGV9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR10AG75", "url": "https://www.uniprot.org/uniprotkb/E1BGV9", "locus": { "chromosome": "15", "start_pos": 78647351, "end_pos": 78648316, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014594", "url": "https://www.ensembl.org/id/ENSBTAG00000014594" } ] } } ], "crossref": [ { "id": "E1BGV9", "url": "https://alphafold.ebi.ac.uk/entry/E1BGV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014594", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014594", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "787428", "url": "https://www.ncbi.nlm.nih.gov/gene/787428", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BGV9", "url": "https://www.uniprot.org/uniprotkb/E1BGV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGV9-1", "url": "https://www.uniprot.org/uniprotkb/E1BGV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSRNVNLEREDHLKITETNLTIMMEFVLLGFTDIPQFQWFLFGIFLVIYMIILLGNGVIILITRVDAILQTPMYFFLRNFSFLEICYVSITLPRMLMDLWTQKGTISLFTCATQMCFFLILGTTECFLLAVMAYDRCVAICDPLHYPLVMCPEVRIRLVVASWISAVPVQIGQTCQIFSLPFCGSNTINHFFCDIPPLLKLACGDIFVNEMVVYIFGILFVTVPFLLILGFYIRIISTILKLPANTGWTKAFSTCSSHITVVLLFYGSATVTYLKPKSNQHEGIDKMISLFYTILTPMVNPIIYSLRNKDVRKAMRKFLP", "length": 321, "header": "tr|E1BGV9-1|E1BGV9_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR10AG75 PE=3 SV=2 CANONICAL=E1BGV9-1" }, "isoforms": [ { "isoform_ac": "E1BGV9-1", "url": "https://www.uniprot.org/uniprotkb/E1BGV9/entry#E1BGV9-1", "sequence": { "sequence": "MQSRNVNLEREDHLKITETNLTIMMEFVLLGFTDIPQFQWFLFGIFLVIYMIILLGNGVIILITRVDAILQTPMYFFLRNFSFLEICYVSITLPRMLMDLWTQKGTISLFTCATQMCFFLILGTTECFLLAVMAYDRCVAICDPLHYPLVMCPEVRIRLVVASWISAVPVQIGQTCQIFSLPFCGSNTINHFFCDIPPLLKLACGDIFVNEMVVYIFGILFVTVPFLLILGFYIRIISTILKLPANTGWTKAFSTCSSHITVVLLFYGSATVTYLKPKSNQHEGIDKMISLFYTILTPMVNPIIYSLRNKDVRKAMRKFLP", "length": 321, "header": "tr|E1BGV9-1|E1BGV9_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR10AG75 PE=3 SV=2 CANONICAL=E1BGV9-1" }, "locus": { "chromosome": "15", "start_pos": 78648316, "end_pos": 78647354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000057312.2", "url": "https://www.ensembl.org/id/ENSBTAT00000057312.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050556.2", "url": "https://www.ensembl.org/id/ENSBTAP00000050556.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:787428", "name": "", "url": 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Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression. As part of the SIN3B complex represses transcription and counteracts the histone acetyltransferase activity of EP300 through the recognition H3K27ac marks by PHF12 and the activity of the histone deacetylase HDAC2. SIN3B complex is recruited downstream of the constitutively active genes transcriptional start sites through interaction with histones and mitigates histone acetylation and RNA polymerase II progression within transcribed regions contributing to the regulation of transcription.", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5#function" }, { "database": "UniProtKB", "id": "ARBA00054574", "url": "https://www.uniprot.org/uniprotkb/ARBA00054574#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SIN3B", "url": "https://www.uniprot.org/uniprotkb/E1BGW5", "locus": { "chromosome": "7", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12346:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02671", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08295", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08295", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16879", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16879", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-400206", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-400206", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8936459", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8936459", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9707564", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9707564", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003586291", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586291", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGW5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAGGGGGVGPAGRGLSGARWGRSGSGGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLSSQENSHSHSDCAESVKQQTLYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLSTKGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMNSVQKSEHEKNLEHSKKRSRPSLLRPVSAPAKKKMKLRGTKDLSIATVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVGPFLGKFPELFAQFKSFLGVKELSFAPPMNDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDCLGGTSEVIQRRAIHRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLVHQFVPSLFFSQQLDLGASEDSADEGRASPQGQAADPGVDRKKPAPGPQSSPPEEKGAAGEAPAPEPQPPQHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGNDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQSIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGAEGASSSPTEGFLLKPVFLQRNLKKFRRWQCEQVRALRGEAKSSWRRLVGVESACNVDCRFKLSTHKMLFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFAEWHSRWLEDNVTVEAASLVQDWLMGEDDEDMVPCKTLCETVRVHGLPVNRYRVQYSRRPASP", "length": 1122, "header": "tr|E1BGW5-1|E1BGW5_BOVIN Isoform 1 of Paired amphipathic helix protein Sin3b OS=Bos taurus OX=9913 GN=SIN3B PE=4 SV=3 CANONICAL=E1BGW5-1" }, "isoforms": [ { "isoform_ac": "E1BGW5-1", "url": "https://www.uniprot.org/uniprotkb/E1BGW5/entry#E1BGW5-1", "sequence": { "sequence": "MAHAGGGGGVGPAGRGLSGARWGRSGSGGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLSSQENSHSHSDCAESVKQQTLYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLSTKGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMNSVQKSEHEKNLEHSKKRSRPSLLRPVSAPAKKKMKLRGTKDLSIATVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVGPFLGKFPELFAQFKSFLGVKELSFAPPMNDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDCLGGTSEVIQRRAIHRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLVHQFVPSLFFSQQLDLGASEDSADEGRASPQGQAADPGVDRKKPAPGPQSSPPEEKGAAGEAPAPEPQPPQHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGNDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQSIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGAEGASSSPTEGFLLKPVFLQRNLKKFRRWQCEQVRALRGEAKSSWRRLVGVESACNVDCRFKLSTHKMLFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFAEWHSRWLEDNVTVEAASLVQDWLMGEDDEDMVPCKTLCETVRVHGLPVNRYRVQYSRRPASP", "length": 1122, "header": "tr|E1BGW5-1|E1BGW5_BOVIN Isoform 1 of Paired amphipathic helix protein Sin3b OS=Bos taurus OX=9913 GN=SIN3B PE=4 SV=3 CANONICAL=E1BGW5-1" }, "locus": { "chromosome": "7", "start_pos": 6224538, "end_pos": 6182306, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036414.6", "url": "https://www.ensembl.org/id/ENSBTAT00000036414.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036272.5", "url": "https://www.ensembl.org/id/ENSBTAP00000036272.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:520505", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520505", "resource": "KEGG Pathway" }, { "id": "R-BTA-400206", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-400206", "resource": "Reactome", "description": "Regulation of lipid metabolism by PPARalpha" }, { "id": "R-BTA-8936459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8936459", "resource": "Reactome", "description": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" }, { "id": "R-BTA-9707564", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9707564", "resource": "Reactome", "description": "Cytoprotection by HMOX1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AD74-1", "protein_name": "SIN3 transcription regulator family member B", "gene_name": "Nwd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTEREALQCTAYPEVQSFCQKHGLAFEAVDLRWGIPNTQATDYLTTELCLEELERCQKTSVGPAFVALLGDQYGPCPVPQRIEEKEWEALRAQLTSRPRDLELVTRHFQRDDNTIPPTYVLQPPGSGVVPGPEEATLTSVLRGGAQEAWRLGLISQEQWMCYHRSVIEWEIEHGLLNSARGDQGATVFLRDVQDLSKHILDDCCLKMVDRLADGCLDTNAQSLLSGLKGRILDAQPGALKSHHLPWSRDLVNPKNKTHARYLKQLSEQFVARTNHQVLEQLRELELARQELGWLYQEIRHHLWQSTESTKVFCGHQELLAQLKQRLRQDESRTHTPLVLFGPPGIGKTSLMCKLAQQVPELLGHKTVAVLRLLGTSKLSLDARSLLRSLSFQLCLAYGLPLPPAQVLEAHSRVGHFFHILLHTVSQRNFESLVLLLDSVDDLDSIRHTPRVSWLPLKCPPRVHLILSACSGQQVLCNLQQTLKDPSAYWEVKALSGSQGQEFIQLLLAAERRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTVPVPLATTAEEATHQFCIRLEETHGQLLVARVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYRDWTPPSKELLRFPPLLWVRLRRDLGHCLVRRPVDGCILLAIAHRQLSQVIQVRYLSGPERAKRHGVLAEFFSGAWSQGIKKLITLPLVGKPLNLDRKVAPQPLWFSGTVANWRKLTELPFHLLHAGCLEELKQEVLGNMSWISCRGISGGIEDLLDDFDMCAPHMDSPEVYLVREAIQLCRPAVELRGLEKSILYTELLARLLFFATSHPAMIGQLCQQAQSWFRACPYPMLVPLAGFLQPPGGPLRATLTGCHKGITAIAWSLEEKLLVVGTQDGTMVVWDVEEQQVVHVLMGHTAEVRCVRVFAQGTLAISASKDHTLRLWSLLSGQEKATILDGGSPNPTEQQGWDLHVDEIKNVVYSTSGTKINVWDLETSKLVFCITGDASDPWVCVALLAAQGLLLALTEGGQVSLWSSAVGKLQEKHQLCSIKEETPTCAVSIQTRARLVVGFSSGSVALVCAGEDRLLEKLPEAVGFLAVSEDDSLLAVGFGRCVRVFLADSQDFHRFMATDLEHEDVVETAVLGPENNLIITASRDALIQVWSLSEQGTLLSVFESAGAPASLLVLCETLVVSASWKSSSFKAWDLRSTQKPPSPTPFLDRTGLATVSHHGSYVYFPKVGDKNKVTIWDLAEGEEQDSLDTSNEVCCLEVAEQTKLLFTGLVSGIVLVFPLNSRQDVLCIPPPEARKAVNCMSVSKSEDRLAIAYDNIVLVLDISPGDLCPAIEGPTYTFYTQLPETIVRVAVLADYRVVYGMSDGSLFLYDCAQSKVFPLEAHGSRVSCVEVSHREQLAVSGAEDALLCLWDLQACREKFKMSYESSYCRGVRCACFSKDDKHVFTGMEDRSIIAWSALDGTLLAVQFVHAVVNRIIPTSNGFMAPTSHGYLIRERFQCPSARASQQDPLKNFKKAVWLIKTRQREDLAEAEAPQDAEPVAVEGKESKSNKHSQVCLIL", "length": 1563 }, "evidence": [ { "id": "E1BGW5", "url": "https://omabrowser.org/oma/group/E1BGW5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S9U7-1", "protein_name": "Paired amphipathic helix protein Sin3b", "gene_name": "SIN3B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAGGGGGGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLSSQENSHNHSDCAENFKQQMPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLSTKGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMSSVQKSEHEKNLEHSKKRSRPSLLRPVSAPAKKKMKLRGTKDLSIATVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDCLGGTSEVIQRRAIHRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLVHQFVPSLFFSQQLDLGASEDSADEGRGSPQGQSTDPGDRKKPAPGPQSSPPEEKGAAGEASAAEQQPPQHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGNDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQSIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRWQCEQVRALRGEAKSSWKRLVGVESACNVDCRFKLSTHKMMFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETAHVHGLPVTRYRVQYSRRPASP", "length": 1121 }, "evidence": [ { "id": "E1BGW5", "url": "https://omabrowser.org/oma/group/E1BGW5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75182-1", "protein_name": "Paired amphipathic helix protein Sin3b", "gene_name": "SIN3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQYSRRPASP", "length": 1162 }, "evidence": [ { "id": "E1BGW5", "url": "https://omabrowser.org/oma/group/E1BGW5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62141-4", "protein_name": "Paired amphipathic helix protein Sin3b", "gene_name": "Sin3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAHAGSGGSAGRGFGGSRWGRSGSGGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLSSQDNSHSHGDCGEDFKQMSYKEDRGQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLHTKGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGSCEMNSGQKNEEKSLEHNKKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKLRLDDCLGGTSEVIQRRAIHRIYGDKAPEVIESLKRNPATAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIRQLLHRFLPSLFFSQQCPGTSDDSADERDRDRDSAEPERRRPTDEKPPADASPEPPKVLDDVYSLFFANNNWYFFLRLHQTLCARLLKIYRQAQKQLLEHRREQEREQLLCEGRREKAADPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYIGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEQQRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRRGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGSEGASSSSTEGFLLKPVFLQRNLKKFRRWQCEQVRAMRGEAKSSWKRLMGVESACDVDCRFRLGTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHRHFEEWHGRWLEDNVTVAAAGLVQDWLMGEEEEDMVPCKTLCETAHVHGLPVTRYRVQYSRRPASP", "length": 1098 }, "evidence": [ { "id": "E1BGW5", "url": "https://omabrowser.org/oma/group/E1BGW5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "pmid": "" }, { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "pmid": "" }, { "name": "XY body", "id": "GO:0001741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001741", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "pmid": "" }, { "name": "X chromosome", "id": "GO:0000805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000805", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "pmid": "" }, { "name": "Y chromosome", "id": "GO:0000806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000806", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "pmid": "" }, { "name": "autosome", "id": "GO:0030849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030849", "evidence": [ { "database": "UniProtKB", "id": "E1BGW5", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1070, "end_pos": 1072, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGW5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1122, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGW5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGW5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGW5" }, { "id": "SM00761", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00761" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone deacetylase interacting", "eco_id": "ECO_0000259", "start_pos": 389, "end_pos": 489, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1070, "end_pos": 1072 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 578, "end_pos": 580 }, { "start_pos": 886, "end_pos": 888 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGX6-1", "uniprot_ac": "E1BGX6", "uniprot_id": "E1BGX6_BOVIN", "mass": { "chemical_mass": 56052.0, "monoisotopic_mass": 56052.0 }, "refseq": { 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"https://alphafold.ebi.ac.uk/entry/E1BGX6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020792", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020792", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03346", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03346", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100336620", "url": "https://www.ncbi.nlm.nih.gov/gene/100336620", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100336620", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336620", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VHFNPYT", "url": "https://omabrowser.org/oma/group/VHFNPYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGX6", "url": "https://www.orthodb.org/?gene=E1BGX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11473", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11473", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11473:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11473:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00351", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00351", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-209931", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-209931", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015326353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326353", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16709", "url": "https://www.rhea-db.org/rhea/16709", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BGX6", "url": "https://www.uniprot.org/uniprotkb/E1BGX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGX6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPAMMMFSSKYWARRGLSLDSAVPEEHQLLTSLTLNKTNSGKNDDKKGNKGSSKNDTATESGKTAVVFSLKNEVGGLVKALKLFQEKHVNMIHIESRKSRRRSSEVEIFVDCECGKTEFNELIQSLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDRCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKHCGYREDNVPQLEDVAAFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI", "length": 491, "header": "tr|E1BGX6-1|E1BGX6_BOVIN Isoform 1 of Tryptophan 5-hydroxylase 2 OS=Bos taurus OX=9913 GN=TPH2 PE=3 SV=3 CANONICAL=E1BGX6-1" }, "isoforms": [ { "isoform_ac": "E1BGX6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGX6/entry#E1BGX6-1", "sequence": { "sequence": "MQPAMMMFSSKYWARRGLSLDSAVPEEHQLLTSLTLNKTNSGKNDDKKGNKGSSKNDTATESGKTAVVFSLKNEVGGLVKALKLFQEKHVNMIHIESRKSRRRSSEVEIFVDCECGKTEFNELIQSLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDRCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKHCGYREDNVPQLEDVAAFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI", "length": 491, "header": "tr|E1BGX6-1|E1BGX6_BOVIN Isoform 1 of Tryptophan 5-hydroxylase 2 OS=Bos taurus OX=9913 GN=TPH2 PE=3 SV=3 CANONICAL=E1BGX6-1" }, "locus": { "chromosome": "5", "start_pos": 1644587, "end_pos": 1542142, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027708.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027708.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027708.6", "url": "https://www.ensembl.org/id/ENSBTAP00000027708.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100336620", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336620", "resource": "KEGG Pathway" }, { "id": "R-BTA-209931", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-209931", "resource": "Reactome", "description": "Serotonin and melatonin biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YNZ0-1", "protein_name": "Tryptophan 5-hydroxylase 2", "gene_name": "TPH2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQPAMMMFSSKYWARRGFSLDSALPEERPGGLTINRSSSGKNEDKKGNKGNGKGESVSEGGKTAVVFSLKNEVGGLVKALRLFQEKHVSMVHIESRKSKRRNSEVEIFVDCDCSKKEFNELIQLLKFQTNIVSLNPPENIWTDEEDLDCVPWFPRKISELDKCSQRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMSYKYGQPIPRVEYTAEEIKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSIFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKAKVKTFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSINRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTSMTSSLLLQKGSSLLADFWEMFCDEMTDSTPTFTRLPKHKQLAHILHCWTFPSTGICNAPSKP", "length": 538 }, "evidence": [ { "id": "E1BGX6", "url": "https://omabrowser.org/oma/group/E1BGX6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SH22-1", "protein_name": "Tryptophan 5-hydroxylase 2", "gene_name": "TPH2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPAMMMFSSKYWARRGLSLDSAVPEEHQLLGSLTLNKSNSGKNDDKKGNKGSGKSDTATESGKTAVVFSLKNEVGGLVKALKLFQEKHVNMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQSLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDLAMGYKYGQPIPRVEYTEEETKTWGIVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSVFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI", "length": 491 }, "evidence": [ { "id": "E1BGX6", "url": "https://omabrowser.org/oma/group/E1BGX6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8CGU9-1", "protein_name": "Tryptophan 5-hydroxylase 2", "gene_name": "Tph2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPAMMMFSSKYWARRGLSLDSAVPEEHQILGGLTQNKATASKSEDKRSGKDTSESSKTAVVFSLKNEVGGLVRALRLFQEKHVNMLHIESRRSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPDNIWTEEEELEDVPWFPRKISELDRCSHRVLMYGTELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQDAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI", "length": 485 }, "evidence": [ { "id": "E1BGX6", "url": "https://omabrowser.org/oma/group/E1BGX6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CGV2-1", "protein_name": "Tryptophan 5-hydroxylase 2", "gene_name": "Tph2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPAMMMFSSKYWARRGLSLDSAVPEDHQLLGSLTQNKAIKSEDKKSGKEPGKGDTTESSKTAVVFSLKNEVGGLVKALRLFQEKHVNMLHIESRRSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPESIWTEEEDLEDVPWFPRKISELDRCSHRVLMYGTELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNLPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKSFDPKTTCLQECLITTFQDAYFVSDSFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI", "length": 488 }, "evidence": [ { "id": "E1BGX6", "url": "https://omabrowser.org/oma/group/E1BGX6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWU9-1", "protein_name": "Tryptophan 5-hydroxylase 2", "gene_name": "TPH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPAMMMFSSKYWARRGFSLDSAVPEEHQLLGSSTLNKPNSGKNDDKGNKGSSKREAATESGKTAVVFSLKNEVGGLVKALRLFQEKRVNMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYIRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI", "length": 490 }, "evidence": [ { "id": "E1BGX6", "url": "https://omabrowser.org/oma/group/E1BGX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "tryptophan 5-monooxygenase activity", "id": "GO:0004510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004510", "evidence": [ { "database": "UniProtKB", "id": "E1BGX6", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "E1BGX6", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "E1BGX6", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "serotonin biosynthetic process", "id": "GO:0042427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042427", "evidence": [ { "database": "UniProtKB", "id": "E1BGX6", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" } ], "pmid": "" }, { "name": "aromatic amino acid metabolic process", "id": "GO:0009072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009072", "evidence": [ { "database": "UniProtKB", "id": "E1BGX6", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16709", "name": "", "equation": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BGX6-1", "A0ABI0NZK3-1" ], "evidence": [ { "id": "16709", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16709" } ] }, { "id": "R-BTA-209828", "name": "Tryptophan is hydroxylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NZK3-1", "E1BGX6-1" ], "evidence": [ { "id": "R-BTA-209828", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-209828" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0ABI0NZK3", "gene_name": "TPH1", "activity": [ { "ec_number": "1.14.16.4", "activity": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin.", "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ] }, { "ec_number": "1.14.16.4", "activity": "", "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ] } ] }, { "uniprot_ac": "E1BGX6", "gene_name": "TPH2", "activity": [ { "ec_number": "1.14.16.4", "activity": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin.", "evidence": [ { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" } ] }, { "ec_number": "1.14.16.4", "activity": "", "evidence": [ { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGX6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 491, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGX6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGX6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" }, { "id": "PS51671", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51671" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ACT", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 141, "start_aa": "Ala", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" }, { "id": "PS51410", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51410" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Biopterin-dependent aromatic amino acid hydroxylase family profile", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 486, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6#function" }, { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" } ], "binding_site_uniprot": 319, "amino_acid": "His", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 319, "end_pos": 319, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6#function" }, { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" } ], "binding_site_uniprot": 324, "amino_acid": "His", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 324, "end_pos": 324, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6#function" }, { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" } ], "binding_site_uniprot": 364, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 364, "end_pos": 364, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.16.4", "ec_name": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin.", "evidence": [ { "id": "1.14.16.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.16.4" }, { "id": "1.14.16.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.16.4" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 37, "end_pos": 39 }, { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BGY8-1", "uniprot_ac": "E1BGY8", "uniprot_id": "E1BGY8_BOVIN", "mass": { "chemical_mass": 40211.0, "monoisotopic_mass": 40211.0 }, "refseq": { "ac": "NP_001179771", "name": "5-hydroxytryptamine receptor 5A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179771" }, "gene_names": [ { "name": "HTR5A", "type": "recommended", "evidence": [ { "id": "E1BGY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGY8" } ] }, { "name": "HTR5A", "type": "synonym", "evidence": [ { "id": "NP_001179771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179771" } ] } ], "protein_names": [ { "name": "5-hydroxytryptamine receptor 5A", "type": "synonym", "evidence": [ { "id": "NP_001179771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179771" }, { "id": "E1BGY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGY8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGY8", "url": "https://www.uniprot.org/uniprotkb/E1BGY8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HTR5A", "url": 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"id": "IPR001397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541200", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541200", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PAVWKSI", "url": "https://omabrowser.org/oma/group/PAVWKSI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGY8", "url": "https://www.orthodb.org/?gene=E1BGY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248:SF202", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248:SF202", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-390666", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-390666", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179771", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179771", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BGY8", "url": "https://www.uniprot.org/uniprotkb/E1BGY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGY8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPPANLSYFTLSTPAPGEANRSSFDAADPRPRLPLLSVFGVLVLTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLMASMAISDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRARRRVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYTVFSTVGAFYLPLGVVLFVYWKIYKAAKLRVGPRKTNSVSPISETVQGKGAAQRPEMVLAARRAKVTFQADGDAWREQKEQRAALMVGILIGVFVLCWIPFFTAELLRPLCACDVPATWKSVFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRHR", "length": 358, "header": "tr|E1BGY8-1|E1BGY8_BOVIN Isoform 1 of 5-hydroxytryptamine receptor 5A OS=Bos taurus OX=9913 GN=HTR5A PE=3 SV=1 CANONICAL=E1BGY8-1" }, "isoforms": [ { "isoform_ac": "E1BGY8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGY8/entry#E1BGY8-1", "sequence": { "sequence": "MDPPANLSYFTLSTPAPGEANRSSFDAADPRPRLPLLSVFGVLVLTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLMASMAISDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRARRRVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYTVFSTVGAFYLPLGVVLFVYWKIYKAAKLRVGPRKTNSVSPISETVQGKGAAQRPEMVLAARRAKVTFQADGDAWREQKEQRAALMVGILIGVFVLCWIPFFTAELLRPLCACDVPATWKSVFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRHR", "length": 358, "header": "tr|E1BGY8-1|E1BGY8_BOVIN Isoform 1 of 5-hydroxytryptamine receptor 5A OS=Bos taurus OX=9913 GN=HTR5A PE=3 SV=1 CANONICAL=E1BGY8-1" }, "locus": { "chromosome": "4", "start_pos": 117000549, "end_pos": 116984176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003759.5", "url": "https://www.ensembl.org/id/ENSBTAT00000003759.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003759.3", "url": "https://www.ensembl.org/id/ENSBTAP00000003759.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": 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"E1BGY8", "url": "https://www.uniprot.org/uniprotkb/E1BGY8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BGY8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 358, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BGY8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BGY8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGY8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 339, "start_aa": "Trp", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 21, "end_pos": 23 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BH00-1", "uniprot_ac": "E1BH00", "uniprot_id": "E1BH00_BOVIN", "mass": { "chemical_mass": 34660.0, "monoisotopic_mass": 34660.0 }, "refseq": { "ac": "NP_001377436", "name": "olfactory receptor family 8 subfamily C member 26", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377436" }, "gene_names": [ { "name": "OR8C26", "type": "recommended", "evidence": [ { "id": "E1BH00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH00" } ] }, { "name": "OR8C26", "type": "synonym", "evidence": [ { "id": "NP_001377436", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377436" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BH00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH00/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 143", "type": "synonym", "evidence": [ { "id": "NP_001377436", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377436" } ] }, { "name": "olfactory receptor family 8 subfamily C member 26", "type": "synonym", "evidence": [ { "id": "NP_001377436", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377436" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377436", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377436" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BH00", "url": "https://www.uniprot.org/uniprotkb/E1BH00#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BH00", "url": "https://www.uniprot.org/uniprotkb/E1BH00" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8C26", "url": "https://www.uniprot.org/uniprotkb/E1BH00", "locus": { "chromosome": "29", "start_pos": 27454639, "end_pos": 27455571, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000035631", "url": "https://www.ensembl.org/id/ENSBTAG00000035631" } ] } } ], "crossref": [ { "id": "E1BH00", "url": "https://alphafold.ebi.ac.uk/entry/E1BH00", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000035631", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000035631", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "787694", "url": "https://www.ncbi.nlm.nih.gov/gene/787694", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:787694", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787694", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TMENDSF", "url": "https://omabrowser.org/oma/group/TMENDSF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BH00", "url": "https://www.orthodb.org/?gene=E1BH00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377436", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377436", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BH00", "url": "https://www.uniprot.org/uniprotkb/E1BH00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH00-1", "url": "https://www.uniprot.org/uniprotkb/E1BH00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNMENASSVTEFILMGLTEQPKLQLPLFFLFLLNYLVTGLGNLCLMILICLNSHLHTPMYFFLFNLSFIDLCYSSVFNPKMLMNFISKRNVISFTGCMSQLFFFCFFVSSECYVLTAMAYDRYVAICKPLLYTVAMSPQVCSLLMSGSYVMGFAGAIVHTGCMMRLIFCGSSIISHYMCDILPLLQLSCSSTYANEFVVSAVVGTVVIVSSLIILISYALILYNILHIPSSKGWSKALSTCGSHITTVGLFYGFGLLTHIRPPSSSFVEQGKFFSVLYTNVVPMLNPLIYSLRNKDVKIAVKKTLKRITK", "length": 310, "header": "tr|E1BH00-1|E1BH00_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR8C26 PE=3 SV=2 CANONICAL=E1BH00-1" }, "isoforms": [ { "isoform_ac": "E1BH00-1", "url": "https://www.uniprot.org/uniprotkb/E1BH00/entry#E1BH00-1", "sequence": { "sequence": "MNMENASSVTEFILMGLTEQPKLQLPLFFLFLLNYLVTGLGNLCLMILICLNSHLHTPMYFFLFNLSFIDLCYSSVFNPKMLMNFISKRNVISFTGCMSQLFFFCFFVSSECYVLTAMAYDRYVAICKPLLYTVAMSPQVCSLLMSGSYVMGFAGAIVHTGCMMRLIFCGSSIISHYMCDILPLLQLSCSSTYANEFVVSAVVGTVVIVSSLIILISYALILYNILHIPSSKGWSKALSTCGSHITTVGLFYGFGLLTHIRPPSSSFVEQGKFFSVLYTNVVPMLNPLIYSLRNKDVKIAVKKTLKRITK", "length": 310, "header": "tr|E1BH00-1|E1BH00_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR8C26 PE=3 SV=2 CANONICAL=E1BH00-1" }, "locus": { "chromosome": "29", "start_pos": 27455571, "end_pos": 27454642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000050119.4", "url": "https://www.ensembl.org/id/ENSBTAT00000050119.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046870.3", "url": "https://www.ensembl.org/id/ENSBTAP00000046870.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:787694", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787694", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZK06-1", "protein_name": "Olfactory receptor", "gene_name": "Or8c16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIEKTMENKSSVSEFILMGLTEQPELQLPLFVLFLMNYTATVMGNLSLMSLISLNSNLHTPVYFFIFNLSFIDFCYSMVSTPKMLMSFVLEKNTISFSGCMTQLFFFCVFINAESYVLTAMAYDRYVAIGQPLMYQVVMSPKICCLLIFGSYLMGFVSAMAHTGCMVRLTFCDSNIINHYMCDIFPLLQLSCSSTYVNELMSYVAVGTAIILCSLIILVSYALILFNIIHMSSGKGWSKALGTCGSHIITVSLFYGSGLLAYVKPSSAETVGQAKFFSVFYTLLVPMLNPLIYSLRNKDVKLAMQKSWKRITS", "length": 313 }, "evidence": [ { "id": "E1BH00", "url": "https://omabrowser.org/oma/group/E1BH00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9EQB2-1", "protein_name": "Olfactory receptor", "gene_name": "Or8c16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "E1BH00", "url": "https://www.uniprot.org/uniprotkb/E1BH00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BH00-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BH00-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BH00" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BH00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH00" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BH42-1", "uniprot_ac": "E1BH42", "uniprot_id": "E1BH42_BOVIN", "mass": { "chemical_mass": 85768.0, "monoisotopic_mass": 85768.0 }, "refseq": { "ac": "XP_005224508", "name": "transcription factor E4F1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224508" }, "gene_names": [ { "name": "E4F1", "type": "recommended", "evidence": [ { "id": "E1BH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ] }, { "name": "E4F1", "type": "synonym", "evidence": [ { "id": "XP_005224508", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224508" } ] } ], "protein_names": [ { "name": "Transcription factor E4F1", "type": "recommended", "evidence": [ { "id": "E1BH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH42/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "E1BH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH42/entry#names_and_taxonomy" } ] }, { "name": "E4F transcription factor 1", "type": "synonym", "evidence": [ { "id": "E1BH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH42/entry#names_and_taxonomy" } ] }, { "name": "Putative E3 ubiquitin-protein ligase E4F1", "type": "synonym", "evidence": [ { "id": "E1BH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH42/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase E4F1", "type": "synonym", "evidence": [ { "id": "E1BH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH42/entry#names_and_taxonomy" } ] }, { "name": "Transcription factor E4F", "type": "synonym", "evidence": [ { "id": "E1BH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH42/entry#names_and_taxonomy" } ] }, { "name": "p120E4F", "type": "synonym", "evidence": [ { "id": "E1BH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH42/entry#names_and_taxonomy" } ] }, { "name": "transcription factor E4F1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005224508", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224508" } ] } ], "function": [ { "annotation": "May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription.", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42#function" }, { "database": "UniProtKB", "id": "ARBA00053485", "url": "https://www.uniprot.org/uniprotkb/ARBA00053485#function" }, { "database": "UniProtKB", "id": "M5FMW3", "url": "https://www.uniprot.org/uniprotkb/M5FMW3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "E4F1", "url": "https://www.uniprot.org/uniprotkb/E1BH42", "locus": { "chromosome": "25", "start_pos": 1761026, "end_pos": 1751354, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009961", "url": "https://www.ensembl.org/id/ENSBTAG00000009961" } ] } } ], "crossref": [ { "id": "E1BH42", "url": "https://alphafold.ebi.ac.uk/entry/E1BH42", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009961", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009961", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515997", "url": "https://www.ncbi.nlm.nih.gov/gene/515997", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515997", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515997", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDSQNEM", "url": "https://omabrowser.org/oma/group/QDSQNEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BH42", "url": "https://www.orthodb.org/?gene=E1BH42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "M5FMW3", "url": "https://www.orthodb.org/?gene=M5FMW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24409:SF295", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24409:SF295", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005224508", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224508", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH42-1", "url": "https://www.uniprot.org/uniprotkb/E1BH42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M5FMW3", "url": "https://www.uniprot.org/uniprotkb/M5FMW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M5FMW3-1", "url": "https://www.uniprot.org/uniprotkb/M5FMW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGAMAVRVTAAHTAEARAEAGREAGEGGVAAAAAALAPGGFLGLPAPFSEEDEDDVHRCGRCQAEFTALEDFVQHKLQKACQRAPQEALPATPAAALLGREQVAPGAASSEEPITVAHIVVEAAALAGDINHSPDIVEAWSSSGLPRGFGASLPAIPSGRAGGGHIKEVIVASEAEPGDSEMAEGPGSSSERGPRLAAEGEQAQVKLLVNKDGRYVCMLCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCAKCGKSFRESGALTRHLKSLTPCTEKIRFSMSKDVVVGKEDVPAGSGASTVGPVTPSSAGEPMETSPVIHLVTDAKGTVIHEVHVQMQELPLGMKALAPEPTSPQELPCSSEGGRENLLHQAMQNSGIVLERAPGEEGALGPATPTASSPQSPGDAAPELPLLEVEQAETQVAGEASSVPRTHPCPQCSETFPTAATLEAHKRGHAGPRPFTCPQCGKAFPKAYLLKKHQEVHVHERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPECGKCYKTKNAQQVHFRTHLEEKPHVCPFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEELLVSEESPTAAAAVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDQEARLGPEAAAADTITIATPESLTEQVAMTLASAISEGTVLTARSGTGGAEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV", "length": 806, "header": "tr|E1BH42-1|E1BH42_BOVIN Isoform 1 of Transcription factor E4F1 OS=Bos taurus OX=9913 GN=E4F1 PE=4 SV=2 CANONICAL=E1BH42-1" }, "isoforms": [ { "isoform_ac": "E1BH42-1", "url": "https://www.uniprot.org/uniprotkb/E1BH42/entry#E1BH42-1", "sequence": { "sequence": "MEGAMAVRVTAAHTAEARAEAGREAGEGGVAAAAAALAPGGFLGLPAPFSEEDEDDVHRCGRCQAEFTALEDFVQHKLQKACQRAPQEALPATPAAALLGREQVAPGAASSEEPITVAHIVVEAAALAGDINHSPDIVEAWSSSGLPRGFGASLPAIPSGRAGGGHIKEVIVASEAEPGDSEMAEGPGSSSERGPRLAAEGEQAQVKLLVNKDGRYVCMLCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCAKCGKSFRESGALTRHLKSLTPCTEKIRFSMSKDVVVGKEDVPAGSGASTVGPVTPSSAGEPMETSPVIHLVTDAKGTVIHEVHVQMQELPLGMKALAPEPTSPQELPCSSEGGRENLLHQAMQNSGIVLERAPGEEGALGPATPTASSPQSPGDAAPELPLLEVEQAETQVAGEASSVPRTHPCPQCSETFPTAATLEAHKRGHAGPRPFTCPQCGKAFPKAYLLKKHQEVHVHERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPECGKCYKTKNAQQVHFRTHLEEKPHVCPFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEELLVSEESPTAAAAVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDQEARLGPEAAAADTITIATPESLTEQVAMTLASAISEGTVLTARSGTGGAEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV", "length": 806, "header": "tr|E1BH42-1|E1BH42_BOVIN Isoform 1 of Transcription factor E4F1 OS=Bos taurus OX=9913 GN=E4F1 PE=4 SV=2 CANONICAL=E1BH42-1" }, "locus": { "chromosome": "25", "start_pos": 1760843, "end_pos": 1751669, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013136.8", "url": "https://www.ensembl.org/id/ENSBTAT00000013136.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013136.6", "url": "https://www.ensembl.org/id/ENSBTAP00000013136.6" } ] } }, { "isoform_ac": "M5FMW3-1", "url": "https://www.uniprot.org/uniprotkb/E1BH42/entry#M5FMW3-1", "sequence": { "sequence": "MEGAMAVRVTAAHTAEARAEAGREAGEGGVAAAAAALAPGGFLGLPAPFSEEDEDDVHRCGRCQAEFTALEDFVQHKLQKACQRAPQEALPATPAAALLGREVAPGAASSEEPITVAHIVVEAAALAGDINHSPDIVGGGHIKEVIVASEAEPGDSEMAEGPGSSSERGPRLAAEGEQAQVKLLVNKDGRYVCMLCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCAKCGKSFRESGALTRHLKSLTPCTEKIRFSMSKDVVVGKEDVPAGSGASTVGPVTPSSAGEPMETSPVIHLVTDAKGTVIHEVHVQMQELPLGMKALAPEPTSPQELPCSSEGGRENLLHQAMQNSGIVLERAPGEEGALGPATPTASSPQSPGDAAPELPLLEVEQAETQVAGEASSVPRTHPCPQCSETFPTAATLEAHKRGHAGPRPFTCPQCGKAFPKAYLLKKHQEVHVHERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPECGKCYKTKNAQQVHFRTHLEEKPHVCPFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEELLVSEESPTAAAAVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDQEARLGPEAAAADTITIATPESLTEQVAMTLASAISEGTVLTARSGTGGAEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV", "length": 781, "header": "tr|M5FMW3-1|E1BH42_BOVIN Computationally mapped isoform of Transcription factor E4F1 OS=Bos taurus OX=9913 GN=E4F1 PE=4 SV=3 CANONICAL=E1BH42-1" }, "locus": { "chromosome": "25", "start_pos": 1760843, "end_pos": 1751669, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084562.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084562.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060309.3", "url": "https://www.ensembl.org/id/ENSBTAP00000060309.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 329, "start_aa": "Thr", "end_pos": 329, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr329", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 637, "start_aa": "Thr", "end_pos": 637, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr637", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 93, "start_aa": "Thr", "end_pos": 93, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr93", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:515997", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515997", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZC00-1", "protein_name": "Transcription factor E4F1", "gene_name": "E4F1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAAVATSAGPAALTAAAAEEREGAAAAGSGPSAGSGAFLSLSAPFSEEDEDDVHKCGRCQAEFTSLEEFVQHKIQKRCQRGPEPPLGPEGPKVVPAVEESITVAHIVVEASSIAEEIGNASAIVGSGHIKEVIVAGDHVFENPNGHIDGDVTEEQGNPDDQEQDIATELIKVKLLVNKEGRYVCELCQKTFKTASILKAHMITHSSRKDYECKLCGTSFRTKGSLIRHHRRHTDERPYKCKKCGKSFRESGALTRHLKSLTPCTEKIRFNVNKEIVVNKDDLPTGSCSSNSETVPSIASESIETSPVIHLVTDAKGNVLHEVHVQMQELPVVDSKSLDEDQSHPKELPCEGETNSENLLRQAMRNSGIVIERVAVEEMQKADEAAVAATEEIKNEVVQAEEEPCGEQHAEVEQSEPTDAERTNGYKSYVCPHCNEAFSEAASLETHIKGHLDYKPFKCEECGKEFTKGYLLKKHQEVHVNERRFRCGECGKLYKTIAHVKGHRRVHSDERPYSCPKCGKRYKTKNAQQVHFRTHLEDKPYVCQYCSRGFREKGSLVRHIRHHTGEKPFKCYKCGRGFAEHGTLNRHLKTKGGCLLALKEVEEVMVSEESQSADNLAATVISEDPHTVLVEFSSVVADTQEYIIETATEDMETSEATEIMEGTRHEVDSHIMKVVQQIVNQANSGHQIIVQNVTVAENSEVTTDAADTITIATPESLTEQVAMTLASAIGEGAVLTTEGSIETEEATVTMVASEDIEIMEHTGEFVIASQEGEVEVQTVIV", "length": 781 }, "evidence": [ { "id": "E1BH42", "url": "https://omabrowser.org/oma/group/E1BH42/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MAM9-1", "protein_name": "Transcription factor E4F1", "gene_name": "E4f1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGAMAVRVTAAHTAEARAEAGHEAGEGGVAAAAALSNGGFLGLPAPFSEEDEDDVHRCGRCQVEFTALEDFVQHKIQKTCHRAPQEALPTTSAATSLLGQEVVPTAAEEGPEEPITVAHIVVEATSLAEDMSHAPDLVGSGHIKEVIVAAEAEPGDGEMAEAPGSPNHQELGLIGEGEQAQVKLLVNKEGRYVCMLCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCAKCGKSFRESGALTRHLKSLTPCTEKIRFSISKDTAVGKEEVPAGSSASTVGTVTSSVAGEPMETSPVIHLVTDAKGTVIHEVHVQMQELPLGMKALTPESADCEELPCSRENSRENLLHQAMQNSGIVLDRVAGEESTLQPAPPSGSSPQSLGDGPSELPLLEVEQIETQVASEAATVPRTHPCSQCSETFPSAATLEAHKRGHIGPRPFTCTQCGKAFPKAYLLKKHQEVHVHERRFRCGDCGKLYKTIAHVRGHRRVHSDERPFPCPQCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEELLVSEESPSAAATVLAEDPHTVLVEFSSVVADTQEYIIEATADDTETSEATEIIEGTQTEVDSHIMKVVQQIVHQAGAGHQIIVQNVTMDQEAALGSEAAAADTITIATPESLTEQVAMTLASAISEGTVLTARAGPNSTEQATVTMVSSEDIEILEHGGELVIASPEGQLEVQTVIV", "length": 783 }, "evidence": [ { "id": "E1BH42", "url": "https://omabrowser.org/oma/group/E1BH42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66K89-1", "protein_name": "Transcription factor E4F1", "gene_name": "E4F1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRCGRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHIVVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPRQQGLGLAGEGEQAQVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLTEQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV", "length": 784 }, "evidence": [ { "id": "E1BH42", "url": "https://omabrowser.org/oma/group/E1BH42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CCE9-1", "protein_name": "Transcription factor E4F1", "gene_name": "E4f1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGAMAVRVTAAHTAEARAEAGREAGEGGVAAAAALSSGGFLGLPAPFSEEDEDDVHRCGRCQVEFTALEDFVQHKIQKTCHRAPQEALPTTPAATALLDQEVVPTAAEGGPDEPITVAHIVVEATSLAEDISHAPDLVGSGHIKEVIVAAEAEPGDVEMAEAPGSPNHQELGLLGEGEQAHVKLLVNKEGRYVCMLCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCAKCGKSFRESGALTRHLKSLTPCTEKIRFSISKDTAVGKEEVPAGSSASTVGTVTSSVAGDPMETSPVIHLVTDAKGTVIHEVHVQMQELPLGMKALTPESPDSEELPCSSENSRENLLHQAMQNSGIVLERVAGEESALEPAPPSGSSPQCLGDGSPELPLLKVEQIETQVASEAATVPRTHPCPQCSETFPTAATLEAHKRGHIAPRPFTCTQCGKAFPKAYLLKKHQEVHVHERRFRCGDCGKLYKTIAHVRGHRRVHSDERPFPCPQCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEELLVSEESPSAAATVLAEDPHTVLVEFSSVVADTQEYIIEATADDTETSEATEIIEGTQTEVDSHIMKVVQQIVHQAGAGHQIIVQNVTMDQETALGSEATAADTITIATPESLTEQVAMTLASAISEGTVLTARAGPNSTEQATVTMVSSEDIEILEHGGELVIASPEGQLEVQTVIV", "length": 783 }, "evidence": [ { "id": "E1BH42", "url": "https://omabrowser.org/oma/group/E1BH42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" }, { "name": "regulation of cell cycle process", "id": "GO:0010564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010564", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": 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"" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" }, { "name": "cAMP response element binding", "id": "GO:0035497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035497", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BH42", "url": "https://www.uniprot.org/uniprotkb/E1BH42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BH42-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 806, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BH42-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BH42" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH42" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 216, "end_pos": 243, "start_aa": "Tyr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 93, 329, 637 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 714, "end_pos": 716 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BH57-1", "uniprot_ac": "E1BH57", "uniprot_id": "E1BH57_BOVIN", "mass": { "chemical_mass": 35015.0, "monoisotopic_mass": 35015.0 }, "refseq": { "ac": "NP_001377688", "name": "olfactory receptor 2Y1", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377688" }, "gene_names": [ { "name": "OR2Y1", "type": "recommended", "evidence": [ { "id": "E1BH57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH57" } ] }, { "name": "OR2Y1", "type": "synonym", "evidence": [ { "id": "NP_001377688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377688" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BH57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH57/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2Y1", "type": "synonym", "evidence": [ { "id": "NP_001377688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377688" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377688" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BH57", "url": "https://www.uniprot.org/uniprotkb/E1BH57#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BH57", "url": "https://www.uniprot.org/uniprotkb/E1BH57" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2Y1", "url": "https://www.uniprot.org/uniprotkb/E1BH57", "locus": { "chromosome": "7", "start_pos": 39950418, "end_pos": 39951356, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038629", "url": "https://www.ensembl.org/id/ENSBTAG00000038629" } ] } } ], "crossref": [ { "id": "E1BH57", "url": "https://alphafold.ebi.ac.uk/entry/E1BH57", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000038629", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038629", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107132626", "url": "https://www.ncbi.nlm.nih.gov/gene/107132626", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:107132626", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107132626", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWKVLWR", "url": "https://omabrowser.org/oma/group/LWKVLWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BH57", "url": "https://www.orthodb.org/?gene=E1BH57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377688", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BH57", "url": "https://www.uniprot.org/uniprotkb/E1BH57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH57-1", "url": "https://www.uniprot.org/uniprotkb/E1BH57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSFNTSFREGFILMGFSDWSQLEPILFVFILVFYSLTIFGNTTIITLSLLERQLHTPMYFFLRHLSFLDLCYTTSTVPQLLINLHGLDRTISYKGCVVQLFSSLALGSTECVLLVVMAFDRYAAVCHPLHYTAIMHPHLCQTLAIASWVGGCMNSLVQTGLMMAMPLCGLHLLNHFFCEMTVLLKLACEDTEGTETKMFVARAIILVVPVLLILGSYVYIVQTVLKVRSVAGRRKAFGTCGSHLLVVSLFYGSAIYTYLQPMHSYSESEGKFVALFYTIVTPMLNPLIYTLRNKDVKGAVRKVLGRGRYSM", "length": 312, "header": "tr|E1BH57-1|E1BH57_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2Y1 PE=3 SV=2 CANONICAL=E1BH57-1" }, "isoforms": [ { "isoform_ac": "E1BH57-1", "url": "https://www.uniprot.org/uniprotkb/E1BH57/entry#E1BH57-1", "sequence": { "sequence": 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[ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF306", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF306", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179516", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179516", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BH68", "url": "https://www.uniprot.org/uniprotkb/E1BH68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH68-1", "url": "https://www.uniprot.org/uniprotkb/E1BH68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHCSCLAKGLPAISAAGNAWIPGLAFPDWAYKAESSPGSRQIQLWHFILELLQKEEFHHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFSKLIVVNYPLWEIRTAPSPCLLLGAPALFQPALLPMGVKSELLHSMLFTHRAMAEQLAGQWTPQGPPEASGNKKGSSSSVHRLGSAPVPCRPGPCCHLGSPLNDLPSFASFTPPLPFAVPSNWPRLSAPFLPPVAPELPFPGSSTPGTLLPGSICAPAAQHFPELPLLARLAQGAEERLRLWSLRPEGLEVKPETTSAPREGFSSERQETSTGEEGPASPSLASFKAVWPLDPP", "length": 358, "header": "tr|E1BH68-1|E1BH68_BOVIN Isoform 1 of ETS variant transcription factor 3 like OS=Bos taurus OX=9913 GN=ETV3L PE=3 SV=1 CANONICAL=E1BH68-1" }, "isoforms": [ { "isoform_ac": "E1BH68-1", "url": "https://www.uniprot.org/uniprotkb/E1BH68/entry#E1BH68-1", "sequence": { "sequence": "MHCSCLAKGLPAISAAGNAWIPGLAFPDWAYKAESSPGSRQIQLWHFILELLQKEEFHHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFSKLIVVNYPLWEIRTAPSPCLLLGAPALFQPALLPMGVKSELLHSMLFTHRAMAEQLAGQWTPQGPPEASGNKKGSSSSVHRLGSAPVPCRPGPCCHLGSPLNDLPSFASFTPPLPFAVPSNWPRLSAPFLPPVAPELPFPGSSTPGTLLPGSICAPAAQHFPELPLLARLAQGAEERLRLWSLRPEGLEVKPETTSAPREGFSSERQETSTGEEGPASPSLASFKAVWPLDPP", "length": 358, "header": "tr|E1BH68-1|E1BH68_BOVIN Isoform 1 of ETS variant transcription factor 3 like OS=Bos taurus OX=9913 GN=ETV3L PE=3 SV=1 CANONICAL=E1BH68-1" }, "locus": { "chromosome": "3", "start_pos": 13773420, "end_pos": 13767022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001144.4", "url": "https://www.ensembl.org/id/ENSBTAT00000001144.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001144.2", "url": "https://www.ensembl.org/id/ENSBTAP00000001144.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 269, "start_aa": "Thr", "end_pos": 269, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr269", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:524013", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524013", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5F8MPE2-1", "protein_name": "Ets variant 3-like", "gene_name": "Etv3l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYCNCFSEGILAAPVNHWVSGLAFPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKKFTYKFNFSKLMVANCPPWKVWAPPSPRLLLRSPALCQPLVPMAKQSEPLYSMLCTRATETQPAGERTPQRPPKASGDKESSSFNCECFGSVLGPGWQRPCCCLRNLQGGLPSPAPLASVPCLCCNWTHLLGPILPPLPSEQSLSGSSKPGPRLSGPMCMPGTWHFPGLHLLARLRQNTGQGLWCQFLRPEELVVNPGPGPSRHLDSNEGLSSGTQGLKLGKGISMSPNPENMRVMWPSDPP", "length": 356 }, "evidence": [ { "id": "E1BH68", "url": "https://omabrowser.org/oma/group/E1BH68/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A9J7KAT1-1", "protein_name": "ETS translocation variant 3-like protein", "gene_name": "Etv3l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHCNCFLEGILTTPVNYWISGLAFPNWAYKAESSPGSRQIQLWHFILALLQKDEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKKILHKTKGKRFTYKFNFSKLSVANCPPWKVWAPSTPHLLLGSTALCQPALVPVAVQSEPLHSTLYTHWATETQLAGERTSWEPLETSGEKGNSSFDGFGSALGPGWQGSCCCFLNLQGDLPSVASFTPAPRLRCNWTHLSGPILPPFSSEQPLSGSSKPGPRLPGPLCMPGAWHFPGLPLLARLRQGTSERLQRRFLRPEELVVNPGPKGHLDSNEGLSSEILGLRPGKGTSMFHNPENLRAMWPLDPS", "length": 354 }, "evidence": [ { "id": "E1BH68", "url": "https://omabrowser.org/oma/group/E1BH68/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F7FJQ8-1", "protein_name": "ETS variant transcription factor 3 like", "gene_name": "Etv3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLQRPHRELRRKHRKQPSLQSKLNPLLPPTMYCNCFSEGIRAAPVNYWISGLAFPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFSKLIVADCPPWKVWTPSTPCLLLRPPALCQTALVPVAEQSEPLRSMLCTRATGTQPARERTPPQPPEASGDKDSSSFSSFGSVLGPGWQNPCCCFWNHQGDLPSFASFAPVPCLCCNWAHLSGPILPPLSSEQPLLESLKPGPRLPGPMWMPGAWHFPGLHLLARLRQGTEAPEVPQAPGIGGKSWPRAKQAPGFQ", "length": 349 }, "evidence": [ { "id": "E1BH68", "url": "https://omabrowser.org/oma/group/E1BH68/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZN32-1", "protein_name": "ETS translocation variant 3-like protein", "gene_name": "ETV3L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHCSCLAEGIPANPGNWISGLAFPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFSKLIVVNYPLWEVRAPPSPHLLLGAPALCRPALVPVGVQSELLHSMLFAHQAMVEQLTGQQTPRGPPETSGDKKGSSSSVYRLGSAPGPCRLGLCCHLGSVQGELPGVASFTPPLPPPLPSNWTCLSGPFLPPLPSEQQLPGAFKPDILLPGPRSLPGAWHFPGLPLLAGLGQGAGERLWLLSLRPEGLEVKPAPMMEAKGGLDPREVFCPETRRLKTGEESLTSPNLENLKAVWPLDPP", "length": 361 }, "evidence": [ { "id": "E1BH68", "url": "https://omabrowser.org/oma/group/E1BH68/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BH68", "url": "https://www.uniprot.org/uniprotkb/E1BH68" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BH68", "url": "https://www.uniprot.org/uniprotkb/E1BH68" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BH68", "url": "https://www.uniprot.org/uniprotkb/E1BH68" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BH68", "url": "https://www.uniprot.org/uniprotkb/E1BH68" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BH68", "url": "https://www.uniprot.org/uniprotkb/E1BH68" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "E1BH68", "url": "https://www.uniprot.org/uniprotkb/E1BH68" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BH68-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 358, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BH68-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BH68" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BH68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH68" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 123, "start_aa": "Ile", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 269 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BH77-1", "uniprot_ac": "E1BH77", "uniprot_id": "E1BH77_BOVIN", "mass": { "chemical_mass": 7725.0, "monoisotopic_mass": 7725.0 }, "refseq": { "ac": "XP_003587571", "name": "cytochrome c oxidase subunit 8A, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587571" }, "gene_names": [ { "name": "LOC783202", "type": "recommended", "evidence": [ { "id": "E1BH77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH77" } ] }, { "name": "LOC783202", "type": "synonym", "evidence": [ { "id": "XP_003587571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587571" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase subunit 8", "type": "recommended", "evidence": [ { "id": "E1BH77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH77/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome c oxidase polypeptide VIII", "type": "synonym", "evidence": [ { "id": "E1BH77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH77/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase subunit 8A, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003587571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587571" } ] } ], "function": [ { "annotation": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.", "evidence": [ { "database": "UniProtKB", "id": "E1BH77", "url": "https://www.uniprot.org/uniprotkb/E1BH77#function" }, { "database": "UniProtKB", "id": "RU368101", "url": "https://www.uniprot.org/uniprotkb/RU368101#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BH77", "url": "https://www.uniprot.org/uniprotkb/E1BH77" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC783202", "url": "https://www.uniprot.org/uniprotkb/E1BH77", "locus": {} } ], "crossref": [ { "id": "E1BH77", "url": "https://alphafold.ebi.ac.uk/entry/E1BH77", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004920", 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376708", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376708" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BH88", "url": "https://www.uniprot.org/uniprotkb/E1BH88#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BH88", "url": "https://www.uniprot.org/uniprotkb/E1BH88" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5B12C", "url": "https://www.uniprot.org/uniprotkb/E1BH88", "locus": { "chromosome": "15", "start_pos": 81671092, "end_pos": 81672036, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000062180", "url": "https://www.ensembl.org/id/ENSBTAG00000062180" } ] } } ], "crossref": [ { "id": "E1BH88", "url": "https://alphafold.ebi.ac.uk/entry/E1BH88", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000051379", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000051379", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506652", "url": "https://www.ncbi.nlm.nih.gov/gene/506652", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:506652", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506652", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGCYVCG", "url": "https://omabrowser.org/oma/group/MGCYVCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BH88", "url": "https://www.orthodb.org/?gene=E1BH88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376708", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376708", 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"evidence": [ { "id": "E1BHA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHA4/entry#names_and_taxonomy" } ] }, { "name": "carbonic anhydrase 7", "type": "synonym", "evidence": [ { "id": "NP_001179451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179451" } ] } ], "function": [ { "annotation": "Reversible hydration of carbon dioxide.", "evidence": [ { "database": "UniProtKB", "id": "E1BHA4", "url": "https://www.uniprot.org/uniprotkb/E1BHA4#function" }, { "database": "UniProtKB", "id": "RU367011", "url": "https://www.uniprot.org/uniprotkb/RU367011#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHA4", "url": "https://www.uniprot.org/uniprotkb/E1BHA4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CA7", "url": "https://www.uniprot.org/uniprotkb/E1BHA4", "locus": { "chromosome": "18", "start_pos": 34557920, "end_pos": 34548834, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020889", "url": "https://www.ensembl.org/id/ENSBTAG00000020889" } ] } } ], "crossref": [ { "id": "E1BHA4", "url": "https://alphafold.ebi.ac.uk/entry/E1BHA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020889", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020889", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03149", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03149", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "520403", "url": "https://www.ncbi.nlm.nih.gov/gene/520403", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001148", "database": "InterPro", "categories": [ "Protein 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"categories": [ "Protein Classification" ] }, { "id": "PTHR18952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952:SF124", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952:SF124", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1475029", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1475029", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179451", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179451", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10748", "url": "https://www.rhea-db.org/rhea/10748", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BHA4", "url": 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"MTGHHGWGYGQNDGPSHWHKLYPIAQGDRQSPINIVSSQAVYSPSLKPLEISYESCTSLSIANNGHSVQVDFNDSDDRTVVSGGPLDGPYRLKQFHFHWGKKHGVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPIRISERQMEKFRSLLFTSEEDERIHMVNNFRPPQPLKGRVVKASFRA", "length": 264, "header": "tr|E1BHA4-1|E1BHA4_BOVIN Isoform 1 of Carbonic anhydrase OS=Bos taurus OX=9913 GN=CA7 PE=3 SV=1 CANONICAL=E1BHA4-1" }, "locus": { "chromosome": "18", "start_pos": 34557262, "end_pos": 34548879, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032353.7", "url": "https://www.ensembl.org/id/ENSBTAT00000032353.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032286.4", "url": "https://www.ensembl.org/id/ENSBTAP00000032286.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:520403", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520403", "resource": "KEGG Pathway" }, { "id": "R-BTA-1475029", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1475029", "resource": "Reactome", "description": "Reversible hydration of carbon dioxide" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B616-1", "protein_name": "Carbonic anhydrase", "gene_name": "CA7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGHHGWGYGQNDGPSHWHKLYPIAQGDRQSPINIVSSQAVYSPSLKPLELSYESCTSLSIANNGHSVQVDFNDSDDRTVVTGGPLDGPYRLKQFHFHWGKKHSVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPISISEKQMEKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA", "length": 264 }, "evidence": [ { "id": "E1BHA4", "url": "https://omabrowser.org/oma/group/E1BHA4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O04846-1", "protein_name": "Alpha carbonic anhydrase 1, chloroplastic", "gene_name": "ACA1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKIMMMIKLCFFSMSLICIAPADAQTEGVVFGYKGKNGPNQWGHLNPHFTTCAVGKLQSPIDIQRRQIFYNHKLNSIHREYYFTNATLVNHVCNVAMFFGEGAGDVIIENKNYTLLQMHWHTPSEHHLHGVQYAAELHMVHQAKDGSFAVVASLFKIGTEEPFLSQMKEKLVKLKEERLKGNHTAQVEVGRIDTRHIERKTRKYYRYIGSLTTPPCSENVSWTILGKVRSMSKEQVELLRSPLDTSFKNNSRPCQPLNGRRVEMFHDHERVDKKETGNKKKKPN", "length": 284 }, "evidence": [ { "id": "E1BHA4", "url": "https://omabrowser.org/oma/group/E1BHA4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P43166-1", "protein_name": "Carbonic anhydrase 7", "gene_name": "CA7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA", "length": 264 }, "evidence": [ { "id": "E1BHA4", "url": "https://omabrowser.org/oma/group/E1BHA4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ERQ8-1", "protein_name": "Carbonic anhydrase 7", "gene_name": "Ca7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGHHCWGYGQDDGPSNWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELFYEACMSLSITNNGHSVQVDFNDSDDRTVVSGGPLEGPYRLKQLHFHWGKKRDMGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAAAAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKDTKAQFSCFNPKCLLPTSRHYWTYPGSLTTPPLSESVTWIVLREPIRISERQMEKFRSLLFTSEDDERIHMVDNFRPPQPLKGRVVKASFQA", "length": 264 }, "evidence": [ { "id": "E1BHA4", "url": "https://omabrowser.org/oma/group/E1BHA4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BHA4", "url": "https://www.uniprot.org/uniprotkb/E1BHA4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BHA4", "url": "https://www.uniprot.org/uniprotkb/E1BHA4" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "E1BHA4", "url": "https://www.uniprot.org/uniprotkb/E1BHA4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "E1BHA4", "url": "https://www.uniprot.org/uniprotkb/E1BHA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10748", "name": "", "equation": "hydrogencarbonate + H(+) = CO2 + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N5D1-1", "G3MX64-1", "E1BAD9-1", "E1BHA4-1", "F1MBS0-1", "F1MPL2-1", "Q95323-1", "P00921-1", "P18915-1", "Q1LZA1-1", "Q3SZX4-1", "F1N0H3-1", "E1BPA4-1", "A0A0A0MP99-1", "A0A3Q1LYT6-1" ], "evidence": [ { "id": "10748", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10748" } ] }, { "id": "R-BTA-1475022", "name": "Carbonic anhydrase dehydrates bicarbonate (cytosol)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-111627" ], "output_participant_list": [], "enzyme_list": [ "G3MX64-1", "Q1LZA1-1", "Q3SZX4-1", "F1N0H3-1", "E1BHA4-1" ], "evidence": [ { "id": "R-BTA-1475022", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1475022" } ] }, { "id": "R-BTA-1475026", "name": "Carbonic anhydrase hydrates carbon dioxide (cytosol)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MX64-1", "Q1LZA1-1", "Q3SZX4-1", "F1N0H3-1", "E1BHA4-1" ], "evidence": [ { "id": "R-BTA-1475026", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1475026" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-111627", "participant_name": "HCO3- [cytosol]", "crossref": [ { "id": "17544", "database": "ChEBI", "url": "" }, { "id": "11533114", "database": "PubChem Substance", "url": "" }, { "id": "C00288", "database": "COMPOUND", "url": "" }, { "id": "ZINC000006827693", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A0A0MP99", "gene_name": "LOC100847874", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A0A0MP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MP99" } ] }, { "ec_number": "4.2.1.69", "activity": "urea = cyanamide + H2O.", "evidence": [ { "id": "A0A0A0MP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MP99" } ] }, { "ec_number": "4.2.1.69", "activity": "", "evidence": [ { "id": "A0A0A0MP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MP99" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A0A0MP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MP99" } ] } ] }, { "uniprot_ac": "A0A3Q1LYT6", "gene_name": "LOC784254", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A3Q1LYT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYT6" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A3Q1LYT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYT6" } ] } ] }, { "uniprot_ac": "E1BAD9", "gene_name": "CA5A", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "E1BAD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAD9" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "E1BAD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAD9" } ] } ] }, { "uniprot_ac": "E1BHA4", "gene_name": "CA7", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "E1BHA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHA4" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "E1BHA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHA4" } ] } ] }, { "uniprot_ac": "E1BPA4", "gene_name": "CA9", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "E1BPA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA4" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "E1BPA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA4" } ] } ] }, { "uniprot_ac": "F1MBS0", "gene_name": "CA6", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "F1MBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS0" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "F1MBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS0" } ] } ] }, { "uniprot_ac": "F1MPL2", "gene_name": "CA12", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "F1MPL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPL2" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "F1MPL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPL2" } ] } ] }, { "uniprot_ac": "F1N0H3", "gene_name": "CA2", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "F1N0H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0H3" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "F1N0H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0H3" } ] } ] }, { "uniprot_ac": "F1N5D1", "gene_name": "CA5B", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "F1N5D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5D1" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "F1N5D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5D1" } ] } ] }, { "uniprot_ac": "G3MX64", "gene_name": "CA13", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "G3MX64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX64" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "G3MX64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX64" } ] } ] }, { "uniprot_ac": "P00921", "gene_name": "CA2", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "P00921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00921" } ] }, { "ec_number": "4.2.1.69", "activity": "urea = cyanamide + H2O.", "evidence": [ { "id": "P00921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00921" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "P00921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00921" } ] } ] }, { "uniprot_ac": "P18915", "gene_name": "CA6", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "P18915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18915" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "P18915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18915" } ] } ] }, { "uniprot_ac": "Q1LZA1", "gene_name": "CA1", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "Q1LZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LZA1" } ] }, { "ec_number": "4.2.1.69", "activity": "urea = cyanamide + H2O.", "evidence": [ { "id": "Q1LZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LZA1" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "Q1LZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LZA1" } ] } ] }, { "uniprot_ac": "Q3SZX4", "gene_name": "CA3", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "Q3SZX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZX4" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "Q3SZX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZX4" } ] } ] }, { "uniprot_ac": "Q95323", "gene_name": "CA4", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "Q95323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95323" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "Q95323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95323" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHA4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 264, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHA4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHA4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHA4" }, { "id": "PS51144", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-carbonic anhydrase", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 262, "start_aa": "His", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.2.1.1", "ec_name": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "4.2.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.1" }, { "id": "4.2.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.1.1" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHA5-1", "uniprot_ac": "E1BHA5", "uniprot_id": "E1BHA5_BOVIN", "mass": { "chemical_mass": 16034.0, "monoisotopic_mass": 16034.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Small ribosomal subunit protein eS19", "type": "recommended", "evidence": [ { "id": "E1BHA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHA5/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S19", "type": "synonym", "evidence": [ { "id": "E1BHA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHA5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHA5", "url": "https://www.uniprot.org/uniprotkb/E1BHA5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BHA5", "locus": {} } ], "crossref": [ { "id": "E1BHA5", "url": "https://alphafold.ebi.ac.uk/entry/E1BHA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000023792", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000023792", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PKWVAKH", "url": "https://omabrowser.org/oma/group/PKWVAKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11710", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11710", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11710:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11710:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BHA5", "url": "https://www.uniprot.org/uniprotkb/E1BHA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHA5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVLEWVDTVKLAKHKELALYDENWFYTPAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH", "length": 145, "header": "tr|E1BHA5-1|E1BHA5_BOVIN Isoform 1 of Small ribosomal subunit protein eS19 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=E1BHA5-1" }, "isoforms": [ { "isoform_ac": "E1BHA5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHA5/entry#E1BHA5-1", "sequence": { "sequence": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVLEWVDTVKLAKHKELALYDENWFYTPAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH", "length": 145, "header": "tr|E1BHA5-1|E1BHA5_BOVIN Isoform 1 of Small ribosomal subunit protein eS19 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=E1BHA5-1" }, "locus": { "chromosome": "9", "start_pos": 42069847, "end_pos": 42069413, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032643.4", "url": "https://www.ensembl.org/id/ENSBTAT00000032643.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050913.1", "url": "https://www.ensembl.org/id/ENSBTAP00000050913.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q9SGA6-1", "protein_name": "Small ribosomal subunit protein eS19z", "gene_name": "RPS19A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGKTVKDVSPHDFVKAYASHLKRSGKIELPTWTDIVKTGKLKELAPYDPDWYYIRAASMARKVYLRGGLGVGAFRRIYGGSKRNGSRPPHFCKSSGGIARHILQQLETMNIVELDTKGGRRITSSGQRDLDQVAGRIAVEP", "length": 143 }, "evidence": [ { "id": "E1BHA5", "url": "https://omabrowser.org/oma/group/E1BHA5/", "database": "OMA" } ], "glygen_name": 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"categories": [ "Protein Classification" ] }, { "id": "VLTWVMW", "url": "https://omabrowser.org/oma/group/VLTWVMW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHC0", "url": "https://www.orthodb.org/?gene=E1BHC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616:SF109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616:SF109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BHC0", "url": "https://www.uniprot.org/uniprotkb/E1BHC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHC0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARTPGPDQPVDGGGEERPAWDNKLQYLLSCVGFAVGLGNLWRFPYLCQTHGGGAFLIPYIIALAFEGIPLFHIELAVGQRLRRGSVGAWTAISPYLGGMGLGCFTVSFLVSLYYNTVLTWVLWYLLNSFQHPLPWSACPLDLNRTGLVQECRDSSPVSYFWYRRTLNVSADIGDSGPVQWRLLVCLAVSWAVVYLCVIRGIETTGKAIYFTALFPYLVLTVFLVRGLTLPGAMQGLTYLFTPDLRVLQNPRVWLDAATQIFFSLSLALGGHIAFASYNPPRNNCRRDAVSIALVNSMTSLYASIAVFSVLGFKAASDHGRCLDRNILHLINAFDLPEQSVSRDTYTAALARLNASQPAQVAGLPLEACRLEDFLDKSASGTGLAFIVFTEAVLHMPGAPVWAVLFFGMLFSLGLSSMFGNMESIITPLLDLGVMPRRVPKEMLTGLACLLCFFTATCFTLRSGSYWLEIFDQYAAALNLILLAFFEVVGVAYVYGMKRFCDDIAWMTGRRPGFYWRATWKVVSPLLLLTIFLAYVALLASSPPHYKAWNPRYERFPLRQEKPYPGWVLAACVLLSFLPTLWVPVVALGQLLAQCRQKTRDPPQDRCPKPRGGRAC", "length": 616, "header": "tr|E1BHC0-1|E1BHC0_BOVIN Isoform 1 of Transporter OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BHC0-1" }, "isoforms": [ { "isoform_ac": "E1BHC0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHC0/entry#E1BHC0-1", "sequence": { "sequence": "MARTPGPDQPVDGGGEERPAWDNKLQYLLSCVGFAVGLGNLWRFPYLCQTHGGGAFLIPYIIALAFEGIPLFHIELAVGQRLRRGSVGAWTAISPYLGGMGLGCFTVSFLVSLYYNTVLTWVLWYLLNSFQHPLPWSACPLDLNRTGLVQECRDSSPVSYFWYRRTLNVSADIGDSGPVQWRLLVCLAVSWAVVYLCVIRGIETTGKAIYFTALFPYLVLTVFLVRGLTLPGAMQGLTYLFTPDLRVLQNPRVWLDAATQIFFSLSLALGGHIAFASYNPPRNNCRRDAVSIALVNSMTSLYASIAVFSVLGFKAASDHGRCLDRNILHLINAFDLPEQSVSRDTYTAALARLNASQPAQVAGLPLEACRLEDFLDKSASGTGLAFIVFTEAVLHMPGAPVWAVLFFGMLFSLGLSSMFGNMESIITPLLDLGVMPRRVPKEMLTGLACLLCFFTATCFTLRSGSYWLEIFDQYAAALNLILLAFFEVVGVAYVYGMKRFCDDIAWMTGRRPGFYWRATWKVVSPLLLLTIFLAYVALLASSPPHYKAWNPRYERFPLRQEKPYPGWVLAACVLLSFLPTLWVPVVALGQLLAQCRQKTRDPPQDRCPKPRGGRAC", "length": 616, "header": "tr|E1BHC0-1|E1BHC0_BOVIN Isoform 1 of Transporter OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BHC0-1" }, "locus": { "chromosome": "20", "start_pos": 71181451, "end_pos": 71166519, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016676.7", "url": "https://www.ensembl.org/id/ENSBTAT00000016676.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016676.5", "url": "https://www.ensembl.org/id/ENSBTAP00000016676.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287BF36-1", "protein_name": "Transporter", "gene_name": "SLC6A18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MACAAGPDPPSASAEDERPQWDNKLQYLLSCVGFAVGLGNLWRFPYLCQTHGGGAFLIPYVIALVFEGIPLFHVELAIGQRLRRGSIGVWRAISPYLGGVGLGCFTVSLLVSLYYNTILAWVLWYLLNSFQHPLPWSTCPLDLNRTGLVQECQDTSPVTYFWYRQTLNITPDINDSGAVQGRLLLCMAASWAVVYLCVIRGIETAGKAIYFTALFPYVVLSVFLVRGLTLPGATEGLLHLFTPDMQVLRNPRVWLDAATQIFFSLSLAFGGHIAFASYNPPRNHCERDAVTIALVNSMTSLYASIAVFSVLGFKAANDHGRCLDGNILLLLNAFDLPDQSVSRDDYAAVLSHLNATQPERVARLPLQVCHLEDFLDKSASGTGLAFIVFAEAVLHMPGAPVWAVLFFGMLFSLGLSSMFGNMESILTPLFDQWVRPRRVPKEVLTGLVCLACFLLASGFTLQSGNYWLEIFDQHAASLNLIFLAFFEVVGVIYVYGMKRFCDDVAWMTGRRPGLYWQVTWKVVSPLLLLTILVAYLALLASRPPSYRAWNPQHEAFPSREEKPYQGWVQVACVLLSFLPSLWVPGVALAQLLAQRRQKQPSAPQDSGGCL", "length": 610 }, "evidence": [ { "id": "E1BHC0", "url": "https://omabrowser.org/oma/group/E1BHC0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LZX3-1", "protein_name": "Transporter", "gene_name": "Slc6a18", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAQASGMDPLVDMEDERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCQTYGGGAFLIPYFIALVFEGIPLFYIELAIGQRLRRGSIGVWRTISPYLGGLGLGCFSVSFLISLYYNTVLLWVLWFFLNSFQYPLPWSTCPLDLNRTGFVQECQSSGTVSYFWYRQTLNITPDINNTGTIQWKLFLCLVACWATVYLCIIRGIESTGKAIYFTALFPYVVLTIFLVRGLTLPGATEGLTYLFTPNMKFLQNPRVWLDAATQIFFSLSLAFGGHIAFASYNPPRNNCEKDAVTIALVNSMTSVYASITIFSIMGFKATNDYWRCLDRNILSLTNEFDFPELSISRDEYPEVLMYLNATQADRLAQLPLKTCHLEDFLDKSASGPGLAFIVFTEAVLHMPGASVWSVLFFGMLFTLGLSSMFGNMESVITPLFDMGILPRSIPKEGMTGMVCLVCFLSAICFTLQSGSYWLEIFDSFAASLNLIIFAFLEVVGVIYVYGMKRFCDDIEWMTGRRPSLYWQVTWKVVSPMLLFSIFLSYIILLSQTPPSYKAWNPQYEHFPSREEKLYPGWVQVTCILLSFLPSLWVPSVALAHLLYQHRQRWKDTHPESGLKPQESRSC", "length": 615 }, "evidence": [ { "id": "E1BHC0", "url": "https://omabrowser.org/oma/group/E1BHC0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O88576-1", "protein_name": "Sodium-dependent neutral amino acid transporter B(0)AT3", "gene_name": "Slc6a18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQASGMDPLVDIEDERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCQTHGGGAFLIPYFIALVFEGIPLFYIELAIGQRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTVLLWVLWFFLNSFQHPLPWSTCPLDLNRTGFVQECQSSGTVSYFWYRQTLNITSDISNTGTIQWKLFLCLVACWSTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLIYLFTPNMKTLQNPRVWLDAATQIFFSLSLAFGGHIAFASYNPPRNNCEKDAVIIALVNSMTSLYASIAIFSVMGFKASNDYGRCLDRNILSLINEFDLPELSISRDEYPSVLMYLNATQTARVAQLPLKTCHLEDFLDKSASGPGLAFIVFTEAVLHMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLLDMGILPKGIPKEVMTGVICFACFLSAICFTLQSGGYWLEIFDSFAASLNLIIFAFMEVVGVIHIYGMKRFCDDIEWMTGRRPGLYWQVTWRVVSPMLLFGIFLSYIVLLIQTPPSYKAWNPQYEHFPSREEKFYPGWVQVTCVLLSFLPSLWVPGVALAQLLSQYKQRWKATHLESGLKLQESRGC", "length": 615 }, "evidence": [ { "id": "E1BHC0", "url": "https://omabrowser.org/oma/group/E1BHC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62687-1", "protein_name": "Sodium-dependent neutral amino acid transporter B(0)AT3", "gene_name": "Slc6a18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQASGMDPLVDIEDERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCHTHGGGAFLIPYFIALVFEGIPLFYIELAIGQRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTILLWVLWFFLNSFQHPLPWSTCPLDLNRTGFVQECQSSGTVSYFWYRQTLNITSDISNTGTIQWKLFLCLVACWTTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLTYLFTPNMKILQNSRVWLDAATQIFFSLSLAFGGHIAFASYNQPRNNCEKDAVTIALVNSMTSLYASITIFSIMGFKASNDYGRCLDRNILSLINEFDFPELSISRDEYPSVLMYLNATQPERVARLPLKTCHLEDFLDKSASGPGLAFIVFTEAVLHMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLFDMGILPKGVPKETMTGVVCFICFLSAICFTLQSGSYWLEIFDSFAASLNLIIFAFMEVVGVIHVYGIKRFCDDIEWMTGRRPSLYWQVTWRVVSPMLLFGIFLSYIVLLAQSSPSYKAWNPQYEHFPSREEKLYPGWVQVTCVLLSFLPSLWVPGIALAQLLFQYRQRWKNTHLESALKPQESRGC", "length": 615 }, "evidence": [ { "id": "E1BHC0", "url": "https://omabrowser.org/oma/group/E1BHC0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96N87-1", "protein_name": "Inactive sodium-dependent neutral amino acid transporter B(0)AT3", "gene_name": "SLC6A18", "tax_id": 9606, "organism": "Homo 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BHC0", "url": "https://www.uniprot.org/uniprotkb/E1BHC0" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "E1BHC0", "url": "https://www.uniprot.org/uniprotkb/E1BHC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BHC0", "url": "https://www.uniprot.org/uniprotkb/E1BHC0" } ], "pmid": "" }, { "name": "neutral L-amino acid:sodium:chloride symporter activity", "id": "GO:0140931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140931", "evidence": [ { "database": "UniProtKB", "id": "E1BHC0", "url": "https://www.uniprot.org/uniprotkb/E1BHC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "E1BHC0", "url": "https://www.uniprot.org/uniprotkb/E1BHC0" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "E1BHC0", "url": "https://www.uniprot.org/uniprotkb/E1BHC0" } ], "pmid": "" }, { "name": "renal amino acid absorption", "id": "GO:1990297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990297", "evidence": [ { "database": "UniProtKB", "id": "E1BHC0", "url": "https://www.uniprot.org/uniprotkb/E1BHC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHC0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 616, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHC0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHC0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 168, "end_pos": 170 }, { "start_pos": 354, "end_pos": 356 } ] }, "class_list": 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF89", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF89", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BHF0", "url": "https://www.uniprot.org/uniprotkb/E1BHF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHF0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMNPLLPASGQQRIPVIPSPFEPPSVDRDLLPPTVAPADPRQFCIPSQFGSSALANANTPNLLSNRVYSGWGILPPESVKAMARRNEMIQRQHTARMEMEMHAIYQQRRIEKVNSKGLAGLGIPFIYGSSIPVGPATYHGRGMLPASDLHLHRSTLRNLQGNPMIVATGPRFTDNWGQKCRRLRRGTGSQKVLDSDTESSKSQVEEKPLGQAHAVLYEENEYTKDPEMEALDNHTLGETSGKPTTALADTCGELEPSHRKPWGAQGTPLEEKAWDEGKEKPSEHGLAACGEKNGVYPPARRSSQPGTHVLLTTKENLSLNEDIQKWTVNDVYNFISGLPGCSDYAQVFKDHAIDGETLPLLTEEHLRSAMGLKLGPALKIQSQVSQHVESMFYKKSLSLPTHTKQAFNQPTDTNPLLDFNSWSDTLDIPCSQDMIVPKGTEDNMRN", "length": 447, "header": "tr|E1BHF0-1|E1BHF0_BOVIN Isoform 1 of Sterile alpha motif domain containing 7 OS=Bos taurus OX=9913 GN=SAMD7 PE=4 SV=3 CANONICAL=E1BHF0-1" }, "isoforms": [ { "isoform_ac": "E1BHF0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHF0/entry#E1BHF0-1", "sequence": { "sequence": "MAMNPLLPASGQQRIPVIPSPFEPPSVDRDLLPPTVAPADPRQFCIPSQFGSSALANANTPNLLSNRVYSGWGILPPESVKAMARRNEMIQRQHTARMEMEMHAIYQQRRIEKVNSKGLAGLGIPFIYGSSIPVGPATYHGRGMLPASDLHLHRSTLRNLQGNPMIVATGPRFTDNWGQKCRRLRRGTGSQKVLDSDTESSKSQVEEKPLGQAHAVLYEENEYTKDPEMEALDNHTLGETSGKPTTALADTCGELEPSHRKPWGAQGTPLEEKAWDEGKEKPSEHGLAACGEKNGVYPPARRSSQPGTHVLLTTKENLSLNEDIQKWTVNDVYNFISGLPGCSDYAQVFKDHAIDGETLPLLTEEHLRSAMGLKLGPALKIQSQVSQHVESMFYKKSLSLPTHTKQAFNQPTDTNPLLDFNSWSDTLDIPCSQDMIVPKGTEDNMRN", "length": 447, "header": "tr|E1BHF0-1|E1BHF0_BOVIN Isoform 1 of Sterile alpha motif domain containing 7 OS=Bos taurus OX=9913 GN=SAMD7 PE=4 SV=3 CANONICAL=E1BHF0-1" }, "locus": { "chromosome": "1", "start_pos": 97458167, "end_pos": 97443572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024261.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024261.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024261.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024261.6" } ] } } ], "glycosylation": [], 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], "pmid": "" }, { "name": "retinal rod cell development", "id": "GO:0046548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046548", "evidence": [ { "database": "UniProtKB", "id": "E1BHF0", "url": "https://www.uniprot.org/uniprotkb/E1BHF0" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "E1BHF0", "url": "https://www.uniprot.org/uniprotkb/E1BHF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHF0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 447, "overlap": "1.0", "method": 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Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription.", "evidence": [ { "database": "UniProtKB", "id": "E1BHF9", "url": "https://www.uniprot.org/uniprotkb/E1BHF9#function" }, { "database": "UniProtKB", "id": "ARBA00056132", "url": "https://www.uniprot.org/uniprotkb/ARBA00056132#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHF9", "url": "https://www.uniprot.org/uniprotkb/E1BHF9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZBTB49", "url": "https://www.uniprot.org/uniprotkb/E1BHF9", "locus": { "chromosome": "6", "start_pos": 104792359, "end_pos": 104819253, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014680", "url": "https://www.ensembl.org/id/ENSBTAG00000014680" } ] } } ], "crossref": [ { "id": "E1BHF9", "url": "https://alphafold.ebi.ac.uk/entry/E1BHF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014680", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014680", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18233", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18233", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BHF9", "url": "https://www.orthodb.org/?gene=E1BHF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BHF9", "url": "https://www.uniprot.org/uniprotkb/E1BHF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHF9-1", "url": "https://www.uniprot.org/uniprotkb/E1BHF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSPGWWSMDPVAAHSCHLLQQLHEQRIQGLLCDCMLVVKGVCFKAHKNVLAAFSQYFRSLFQNSSGQKNDVFHLDIKNVSGIGQILDFMYTSHLDLNQDNIQVMLDTAQCLQVQNVLSLCHTFLKSATIDQPPGLPCHGTFSLQSTLTPDTNCVLSENYPPHLLPECSAGAQQCRAVDGSLSHAPPSVGLHPPTAETSKQAPDPFDGSCTELPFKQPNCYYKLRNLYSKQYYKHASCPSHERVTEQPFTFSASADLHAEDRRPYAVGHTECVLESSQHLPSNFLAQPLGENAPDPASDHAGQQPTRQMRLKKAIHLKKLNFLKSQKSAEQTSEPKPNDSLTMRLEAAREHSVEKVNSPSAEEKESEELSNSENFNGVSETERPEDPAALEDQTQLPQSQRQYACELCGKPFKHPSNLELHRRSHTGEKPFECNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASGDVQRHIIIHSGEKPHLCDICGRGFSNFSNLKEHKKTHTADKVFTCDECGKSFNMQRKLVKHRIRHTGERPYSCSACGKCFGGSGDLRRHVRTHTGEKPYTCDVCNKCFTRSAVLRRHKKTHCRASDEGPGALEALARAIEAPDLERSQSSDSFSQDVSVPLMPAVTVKIPAHPVDENSVAGFDSPCKFQPVAQPQHGPSESEKLSLEPVKLAKPPHVPLAQHQAYGYPDVDAPAGAEPLQADGVAALRSSLAALDHPPCTDPLGSRAAAPAYRNSEGQFFSSMTLWGLAMKTLQNESELDQ", "length": 773, "header": "tr|E1BHF9-1|E1BHF9_BOVIN Isoform 1 of Zinc finger and BTB domain-containing protein 49 OS=Bos taurus OX=9913 GN=ZBTB49 PE=3 SV=4 CANONICAL=E1BHF9-1" }, "isoforms": [ { "isoform_ac": "E1BHF9-1", 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ubiquitin-protein transferase RMND5A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192761" }, "gene_names": [ { "name": "RMND5A", "type": "recommended", "evidence": [ { "id": "E1BHI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHI2" } ] }, { "name": "RMND5A", "type": "synonym", "evidence": [ { "id": "NP_001192761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192761" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein transferase RMND5A", "type": "synonym", "evidence": [ { "id": "NP_001192761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192761" } ] }, { "name": "Required for meiotic nuclear division 5 homolog A", "type": "synonym", "evidence": [ { "id": "E1BHI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHI2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.", "evidence": [ { "database": "UniProtKB", "id": "E1BHI2", "url": "https://www.uniprot.org/uniprotkb/E1BHI2#function" }, { "database": "UniProtKB", "id": "ARBA00059500", "url": "https://www.uniprot.org/uniprotkb/ARBA00059500#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHI2", "url": "https://www.uniprot.org/uniprotkb/E1BHI2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RMND5A", "url": "https://www.uniprot.org/uniprotkb/E1BHI2", "locus": { "chromosome": "11", "start_pos": 48140282, "end_pos": 48196246, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021140", "url": "https://www.ensembl.org/id/ENSBTAG00000021140" } ] } } ], "crossref": [ { "id": "E1BHI2", "url": "https://alphafold.ebi.ac.uk/entry/E1BHI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021140", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021140", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16794", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16794", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "516731", "url": "https://www.ncbi.nlm.nih.gov/gene/516731", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516731", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516731", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LIRECKM", "url": "https://omabrowser.org/oma/group/LIRECKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHI2", "url": "https://www.orthodb.org/?gene=E1BHI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12170:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12170:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10607", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9861718", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9861718", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192761", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192761", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BHI2", "url": "https://www.uniprot.org/uniprotkb/E1BHI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHI2-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLVLTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF", "length": 391, "header": "tr|E1BHI2-1|E1BHI2_BOVIN Isoform 1 of Required for meiotic nuclear division 5 homolog A OS=Bos taurus OX=9913 GN=RMND5A PE=4 SV=1 CANONICAL=E1BHI2-1" }, "isoforms": [ { "isoform_ac": "E1BHI2-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI2/entry#E1BHI2-1", "sequence": { "sequence": "MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLVLTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF", "length": 391, "header": "tr|E1BHI2-1|E1BHI2_BOVIN Isoform 1 of Required for meiotic nuclear division 5 homolog A OS=Bos taurus OX=9913 GN=RMND5A PE=4 SV=1 CANONICAL=E1BHI2-1" }, "locus": { "chromosome": "11", "start_pos": 48196047, "end_pos": 48140440, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028174.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028174.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028174.4", "url": "https://www.ensembl.org/id/ENSBTAP00000028174.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:516731", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516731", "resource": "KEGG Pathway" }, { "id": "R-BTA-9861718", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9861718", "resource": "Reactome", "description": "Regulation of pyruvate metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BGA6-1", "protein_name": "Required for meiotic nuclear division 5 homolog A", "gene_name": "RMND5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASQGKDSREGGNSELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLVLTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF", "length": 396 }, "evidence": [ { "id": "E1BHI2", "url": "https://omabrowser.org/oma/group/E1BHI2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q555R9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEESVSNNGGSGGGGNKVEFDQLDDGLTRIIKKQKTCLSKAISDIDTIISSLKQCKQVLSLSSNNDNNIDNNIETTNDIIPKAISKLNQSLIDSKLCTKLVSEHKELHAPISKFGKLVDKNFRNDIEKSTKDIGFDTKILNKVILNHLYRVGKFEIGDIFANEIGIDKKVAISIKDCFIEHHKILESIEQFNLKPVIEWCRLHREGLSSIDSSLEFKLHRLHIIQLLKNQKSDDALQYARDYLEEFSTTHMKDLQQLMGTFLFAKRLDQSPYKDIFEQQSIDDQWFEIRNTFSRDNCSLMGLPQESPLSITITVGIKSLPTLLKLSSFSVLKGVNDDSLTVEINVDEKYKFHSVFACPVSREQSTSQNPPVMLFCGHLLCKNSMQRLLKGSSNRFKCPYCPAEQNLSNVKTVYF", "length": 414 }, "evidence": [ { "id": "E1BHI2", "url": "https://omabrowser.org/oma/group/E1BHI2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q80YQ8-1", "protein_name": "E3 ubiquitin-protein ligase RMND5A", "gene_name": "Rmnd5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLVLTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF", "length": 391 }, "evidence": [ { "id": "E1BHI2", "url": "https://omabrowser.org/oma/group/E1BHI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96G75-1", "protein_name": "E3 ubiquitin-protein transferase RMND5B", "gene_name": "RMND5B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQCACVERELDKVLQKFLTYGQHCERSLEELLHYVGQLRAELASAALQGTPLSATLSLVMSQCCRKIKDTVQKLASDHKDIHSSVSRVGKAIDRNFDSEICGVVSDAVWDAREQQQQILQMAIVEHLYQQGMLSVAEELCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLEFKLHRLHFIRLLAGGPAKQLEALSYARHFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCHLLDSSHWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCTGVWNHKDELPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGGKLKCPYCPMEQNPADGKRIIF", "length": 393 }, "evidence": [ { "id": "E1BHI2", "url": "https://omabrowser.org/oma/group/E1BHI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W2N5-1", "protein_name": "Souji", "gene_name": "Sou", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDSESLACSSVEKDLTRVVSKLEQLHENAEADIGDIATQMSELVEVLSRAEQLVTTLNSSTQVSQDDPMGDAVSMQVETEPTAPQRLTERQVESVRNALARCHERVQKLSTEHRDLHGSISKIGKAIDRNFSADFSSTMRVDVLQDEENLMLLNKAIAKHYCRQGMDDVARTLIRECKMSPEHAQDVFDSEREFADIYGIWVKIQKRDLTDALKWAKMYSQQLSDRHSLIEFRLHRMRFMQLVSYGLDSQREAISYARLNFKKFAVRYEHEIANLMASFIYLPSGLENSPYKHFLGQEKWTELSFIFLKDACQLLGISKNSALSVVVNAGCTALPALLNIKQVMQSRQVLGMWNGCDELPIEIDLQPEFRFHSIFACPILRQQTSEDNPPKKLTCGHVISNDALHKLSVGHILKCPYCPVEQNAEEAVRIYF", "length": 432 }, "evidence": [ { "id": "E1BHI2", "url": "https://omabrowser.org/oma/group/E1BHI2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BHI2", "url": "https://www.uniprot.org/uniprotkb/E1BHI2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BHI2", "url": "https://www.uniprot.org/uniprotkb/E1BHI2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BHI2", "url": "https://www.uniprot.org/uniprotkb/E1BHI2" } ], "pmid": "" }, { "name": "GID complex", "id": "GO:0034657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657", "evidence": [ { "database": "UniProtKB", "id": "E1BHI2", "url": "https://www.uniprot.org/uniprotkb/E1BHI2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BHI2", "url": "https://www.uniprot.org/uniprotkb/E1BHI2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BHI2", "url": "https://www.uniprot.org/uniprotkb/E1BHI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "E1BHI2", "url": "https://www.uniprot.org/uniprotkb/E1BHI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHI2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 391, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHI2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHI2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHI2" }, { "id": "PS50897", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50897" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CTLH", "eco_id": "ECO_0000259", "start_pos": 153, "end_pos": 210, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BHI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHI2" }, { "id": "PS51867", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51867" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-Gid-type", "eco_id": "ECO_0000259", "start_pos": 336, "end_pos": 377, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 368, "end_pos": 370 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHI7-1", "uniprot_ac": "E1BHI7", "uniprot_id": "E1BHI7_BOVIN", "mass": { "chemical_mass": 59151.0, "monoisotopic_mass": 59151.0 }, "refseq": {}, "gene_names": [ { "name": "BTN1A1", "type": "recommended", "evidence": [ { "id": "E1BHI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHI7" } ] } ], "protein_names": [ { "name": "Butyrophilin subfamily 1 member A1", "type": "synonym", "evidence": [ { "id": "E1BHI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHI7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHI7", "url": "https://www.uniprot.org/uniprotkb/E1BHI7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BTN1A1", "url": "https://www.uniprot.org/uniprotkb/E1BHI7", "locus": { "chromosome": "23", "start_pos": 31585191, "end_pos": 31591478, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000031753", "url": "https://www.ensembl.org/id/ENSBTAG00000031753" } ] } } ], "crossref": [ { "id": "E1BHI7", "url": "https://alphafold.ebi.ac.uk/entry/E1BHI7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000031753", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000031753", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05713", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05713", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15819", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15819", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "282157", "url": "https://www.ncbi.nlm.nih.gov/gene/282157", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AHMELRW", "url": "https://omabrowser.org/oma/group/AHMELRW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100:SF138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100:SF138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8851680", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8851680", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BHI7", "url": "https://www.uniprot.org/uniprotkb/E1BHI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHI7-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZQ4", "url": "https://www.uniprot.org/uniprotkb/F1MZQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZQ4-1", "url": "https://www.uniprot.org/uniprotkb/F1MZQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVFPNSCLAGCLLIFILLQLPKLDSAPFDVIGPPEPILAVVGEDAELPCRLSPNVSAKGMELRWFREKVSPAVFVSREGQEQEGEEMAEYRGRVSLVEDHIAEGSVAVRIQEVKASDDGEYRCFFRQDENYEEAIVHLKVAALGSDPHISMKVQESGEIQLECTSVGWYPEPQVQWRTHRGEEFPSMSESRNPDEEGLFTVRASVIIRDSSMKNVSCCIRNLLLGQEKDVEVSIPASFFPRLTPWMVAVAVILVVLGLLTIGSIFFTWRLYKERSRQRRNEFSSKEKLLEELSKFTFSLSLVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKPERFDSWPCVMGREAFTSGRHYWEVEVGDRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYGNGYWALTPLRTPLPLAGPPRRVGVFLDYESGDIFFYNMTDGSHIYTFSKASFSGPLRPFFCLWSCGKKPLTICPVTDGLEGVMVVADAKDISKEIPLSPMGEDSASGDIETLHSKLIPLQPSQGVP", "length": 526, "header": "tr|E1BHI7-1|E1BHI7_BOVIN Isoform 1 of Butyrophilin subfamily 1 member A1 OS=Bos taurus OX=9913 GN=BTN1A1 PE=3 SV=3 CANONICAL=E1BHI7-1" }, "isoforms": [ { "isoform_ac": "E1BHI7-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI7/entry#E1BHI7-1", "sequence": { "sequence": "MAVFPNSCLAGCLLIFILLQLPKLDSAPFDVIGPPEPILAVVGEDAELPCRLSPNVSAKGMELRWFREKVSPAVFVSREGQEQEGEEMAEYRGRVSLVEDHIAEGSVAVRIQEVKASDDGEYRCFFRQDENYEEAIVHLKVAALGSDPHISMKVQESGEIQLECTSVGWYPEPQVQWRTHRGEEFPSMSESRNPDEEGLFTVRASVIIRDSSMKNVSCCIRNLLLGQEKDVEVSIPASFFPRLTPWMVAVAVILVVLGLLTIGSIFFTWRLYKERSRQRRNEFSSKEKLLEELSKFTFSLSLVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKPERFDSWPCVMGREAFTSGRHYWEVEVGDRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYGNGYWALTPLRTPLPLAGPPRRVGVFLDYESGDIFFYNMTDGSHIYTFSKASFSGPLRPFFCLWSCGKKPLTICPVTDGLEGVMVVADAKDISKEIPLSPMGEDSASGDIETLHSKLIPLQPSQGVP", "length": 526, "header": "tr|E1BHI7-1|E1BHI7_BOVIN Isoform 1 of Butyrophilin subfamily 1 member A1 OS=Bos taurus OX=9913 GN=BTN1A1 PE=3 SV=3 CANONICAL=E1BHI7-1" }, "locus": { "chromosome": "23", "start_pos": 31591420, "end_pos": 31586246, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045016.5", "url": "https://www.ensembl.org/id/ENSBTAT00000045016.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042445.4", "url": "https://www.ensembl.org/id/ENSBTAP00000042445.4" } ] } }, { "isoform_ac": "F1MZQ4-1", "url": "https://www.uniprot.org/uniprotkb/E1BHI7/entry#F1MZQ4-1", "sequence": { "sequence": "MAVFPNSCLAGCLLIFILLQLPKLDSAPFDVIGPPEPILAVVGEDAELPCRLSPNVSAKGMELRWFREKVSPAVFVSREGQEQEGEEMAEYRGRVSLVEDHIAEGSVAVRIQEVKASDDGEYRCFFRQDENYEEAIVHLKVAALGSDPHISMKVQESGEIQLECTSVGWYPEPQVQWRTHRGEEFPSMSESRNPDEEGLFTVRASVIIRDSSMKNVSCCIRNLLLGQEKDVEVSIPASFFPRLTPWMVAVAVILVVLGLLTIGSIFFTWRLYKERSRQRRNEFSSKEKLLEELKWKRATLHAVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKPERFDSWPCVMGREAFTSGRHYWEVEVGDRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYGNGYWALTPLRTPLPLAGPPRRVGVFLDYESGDIFFYNMTDGSHIYTFSKASFSGPLRPFFCLWSCGKKPLTICPVTDGLEGVMVVADAKDISKEIPLSPMGEDSASGDIETLHSKLIPLQPSQGVP", "length": 526, "header": "tr|F1MZQ4-1|E1BHI7_BOVIN Computationally mapped isoform of Butyrophilin subfamily 1 member A1 OS=Bos taurus OX=9913 GN=BTN1A1 PE=3 SV=3 CANONICAL=E1BHI7-1" }, "locus": { "chromosome": "23", "start_pos": 31591420, "end_pos": 31586246, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045021.4", "url": "https://www.ensembl.org/id/ENSBTAT00000045021.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042450.4", "url": "https://www.ensembl.org/id/ENSBTAP00000042450.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8851680", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8851680", "resource": "Reactome", "description": "Butyrophilin (BTN) family interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0U712-1", "protein_name": "Butyrophilin subfamily 1 member A1", "gene_name": "BTN1A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTVFRSSCLLSCLLIFILLQLPELDAAHFDVIGPPEPILAVVGEDAELPCRLSPNVSAERMELRWFRKKVSPAVFVRREGREQAGEQMPEYRGRVTLVEDDIAAGHVAVRIQGVKASDDGEYRCFFRQDENYEEAIVHLKVAALGSDPQIHMEVQESGEIQLECTSMGWYPEPWVQWRTPKGEEFPSMSESKSPNEEGLFTVAASVIIRDPSVKNVSCYVRNLLLGQEKEVEISIPAPFFPKLIPWMVVVAVVLVVVGLLTIGSIFFTWRLYKERSRQRRGEISTKQKLLEELKWKKATLHAVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKPERFDSWPCVLGRETFTSGRHYWEVEVGDRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYGNGYWALTPLRTPLPLAGPPRRVGIFLDYESGDISFYNMTDGSHIYSFPSASFSGPLRPFFCLWSCGKKPLTICPITDGLEGVTVVADAKDLSKEIPLSPMGGESASGDTDTLHSKLIPTQPSQGVP", "length": 526 }, "evidence": [ { "id": "E1BHI7", "url": "https://omabrowser.org/oma/group/E1BHI7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1LRV5-1", "protein_name": "Butyrophilin, subfamily 1, member A1", "gene_name": "Btn1a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVPTNSCPLVCLLTFTVLQLPTLDSAAPFNVTAPQESVLAVVGSDAELTCRFSPNASSEQMELLWFRQTRSPAVLLYRAGQEQEGEQMTEYHGRATLVTARLLDGLATLRIRGVRVSDQGQYRCFLKDNDDSEEAAVHLKVAAVGSDPYISMKVQENGDMELECTSSGWYPEPQVQWRTANREMLPPTSESRNPDTEGLFTVTASMMIRDNSIKNMSCCIQNILLGQGKEVEISLPAPFLPRLTPWIVALAIVILALGFLAIGSIFFTWKLYKERSRERKKEFGSKERLLEELRCKKTALHEVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQILPDRPERFDSWPCVLGRETFTSGRHYWEVEVGDRTDWAIGVCRENVVKKGFDPMTPDNGFWAVELYGNGYWALTPLRTPLRLAGPPRRVGVFLDYELGDISFYNMSDGSLIYAFPSISFSGPLRPFFCLWSCGKKPLTICPTANVPEKITVIANVQDNIPLSPLGEGSTSGDKDSLHSKLIPFSPSQAAP", "length": 524 }, "evidence": [ { "id": "E1BHI7", "url": "https://omabrowser.org/oma/group/E1BHI7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13410-1", "protein_name": "Butyrophilin subfamily 1 member A1", "gene_name": "BTN1A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVFPSSGLPRCLLTLILLQLPKLDSAPFDVIGPPEPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSPAVLVHRDGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSDDGEYTCFFREDGSYEEALVHLKVAALGSDPHISMQVQENGEICLECTSVGWYPEPQVQWRTSKGEKFPSTSESRNPDEEGLFTVAASVIIRDTSAKNVSCYIQNLLLGQEKKVEISIPASSLPRLTPWIVAVAVILMVLGLLTIGSIFFTWRLYNERPRERRNEFSSKERLLEELKWKKATLHAVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKTERFDSWPCVLGRETFTSGRHYWEVEVGDRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYGNGYWALTPLRTPLPLAGPPRRVGIFLDYESGDISFYNMNDGSDIYTFSNVTFSGPLRPFFCLWSSGKKPLTICPIADGPERVTVIANAQDLSKEIPLSPMGEDSAPRDADTLHSKLIPTQPSQGAP", "length": 526 }, "evidence": [ { "id": "E1BHI7", "url": "https://omabrowser.org/oma/group/E1BHI7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62556-1", "protein_name": "Butyrophilin subfamily 1 member A1", "gene_name": "Btn1a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVPTNSCLLVCLLTLTVLQLPTLDSAAPFDVTAPQEPVLALVGSDAELTCGFSPNASSEYMELLWFRQTRSTAVLLYRDGQEQEGQQMTEYRGRATLATAGLLDGRATLLIRDVRVSDQGEYRCLFKDNDDFEEAAVYLKVAAVGSDPQISMTVQENGEMELECTSSGWYPEPQVQWRTGNREMLPSTSESKKHNEEGLFTVAVSMMIRDSSIKNMSCCIQNILLGQGKEVEISLPAPFVPRLTPWIVAVAIILLALGFLTIGSIFFTWKLYKERSSLRKKEFGSKERLLEELRCKKTVLHEVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQILPDRPERFDSWPCVLGRETFTSGRHYWEVEVGDRTDWAIGVCRENVVKKGFDPMTPDNGFWAVELYGNGYWALTPLRTSLRLAGPPRRVGVFLDYDAGDISFYNMSNGSLIYTFPSISFSGPLRPFFCLWSCGKKPLTICSTANGPEKVTVIANVQDDIPLSPLGEGCTSGDKDTLHSKLIPFSPSQAAP", "length": 524 }, "evidence": [ { "id": "E1BHI7", "url": "https://omabrowser.org/oma/group/E1BHI7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "E1BHI7", "url": 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"publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B0V349-1", "protein_name": "Claudin", "gene_name": "cldn26", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLFTTKFVQRASLFVSFGGLVTTFVTTFLPLWKTMNSDLNEMENWYEGLWHMCIYTEEVGIHCKAFDSFLALPPDTFAGRVLMCISIATGILGVAAAFFGLRGVEIGASRERMKRNLLILGGVFVVVSGVTTLAAVSFMAYVMVVKFWDDDRPEVMPGWEYGEAMFSAWFAGLLLVVGGSFLFVAVCMGDHEVKLQTEMIARCQEQRPRSLHYRKTEII", "length": 220 }, "evidence": [ { "id": "E1BHK4", "url": "https://omabrowser.org/oma/group/E1BHK4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N7P3-1", "protein_name": "Claudin-22", "gene_name": "CLDN22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEVGMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCAACSSHAPLASGHYAVAQTQDHHQELETRNTNLKH", "length": 220 }, "evidence": [ { "id": "E1BHK4", "url": "https://omabrowser.org/oma/group/E1BHK4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7U6-1", "protein_name": "Claudin-22", "gene_name": "Cldn22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLVFRTATQAAALLLSLLGWVLSCLTNYLPHWKNLNLELNEMENWTMGLWKSCVIQEEVGRQCKDFDSFLALPAELQVSRVLMSLCNGLGLLGLLASGCGLDCLRLGETQEGLKKRLLTLGGTLLWTSGVMVLVPVSWVAHKTVREFWDETMPEIVPRWEFGEALFLGWFAGFCLVLGGCVLHCAACWSPAPAASSHYAVAGPRDHQQHLELKQANPEI", "length": 220 }, "evidence": [ { "id": "E1BHK4", "url": "https://omabrowser.org/oma/group/E1BHK4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BHK4", "url": "https://www.uniprot.org/uniprotkb/E1BHK4" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "E1BHK4", "url": "https://www.uniprot.org/uniprotkb/E1BHK4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "E1BHK4", "url": "https://www.uniprot.org/uniprotkb/E1BHK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHK4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 220, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHK4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHK4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHL0-1", "uniprot_ac": "E1BHL0", "uniprot_id": "E1BHL0_BOVIN", "mass": { "chemical_mass": 55242.0, "monoisotopic_mass": 55242.0 }, "refseq": { "ac": "XP_002691196", "name": "CCR4-NOT transcription complex subunit 11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691196" }, "gene_names": [ { "name": "CNOT11", "type": "recommended", "evidence": [ { "id": "E1BHL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL0" } ] }, { "name": "CNOT11", "type": "synonym", "evidence": [ { "id": "XP_002691196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691196" } ] } ], "protein_names": [ { "name": "CCR4-NOT transcription complex subunit 11", "type": "recommended", "evidence": [ { "id": "E1BHL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL0/entry#names_and_taxonomy" } ] }, { "name": "CCR4-NOT transcription complex subunit 11", "type": "synonym", "evidence": [ { "id": "XP_002691196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691196" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHL0", "url": "https://www.uniprot.org/uniprotkb/E1BHL0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CNOT11", "url": "https://www.uniprot.org/uniprotkb/E1BHL0", "locus": { "chromosome": "11", "start_pos": 6178876, "end_pos": 6164471, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008267", "url": "https://www.ensembl.org/id/ENSBTAG00000008267" } ] } } ], "crossref": [ { "id": "E1BHL0", "url": "https://alphafold.ebi.ac.uk/entry/E1BHL0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008267", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008267", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "506268", "url": "https://www.ncbi.nlm.nih.gov/gene/506268", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:506268", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506268", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDHSVQW", "url": "https://omabrowser.org/oma/group/PDHSVQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHL0", "url": "https://www.orthodb.org/?gene=E1BHL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15975", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15975", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15975:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15975:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10155", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10155", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-429947", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-429947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6804115", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804115", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002691196", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691196", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BHL0", "url": "https://www.uniprot.org/uniprotkb/E1BHL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHL0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGGGASASSGRLLTAAEQRGTREAAGSASRSGPGGSGSGGRGGAGVPGPGSGGPGGPAGRMSLTPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPPRELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDPDSSNSGFDSSVASQITEALVSGPKPPIESHFRPEFIRPPPPLHVCEDELAWLNPTEPDHAIQWDKSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGETPAETKVSK", "length": 511, "header": "tr|E1BHL0-1|E1BHL0_BOVIN Isoform 1 of CCR4-NOT transcription complex subunit 11 OS=Bos taurus OX=9913 GN=CNOT11 PE=3 SV=1 CANONICAL=E1BHL0-1" }, "isoforms": [ { "isoform_ac": "E1BHL0-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL0/entry#E1BHL0-1", "sequence": { "sequence": "MPGGGASASSGRLLTAAEQRGTREAAGSASRSGPGGSGSGGRGGAGVPGPGSGGPGGPAGRMSLTPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPPRELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDPDSSNSGFDSSVASQITEALVSGPKPPIESHFRPEFIRPPPPLHVCEDELAWLNPTEPDHAIQWDKSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGETPAETKVSK", "length": 511, "header": "tr|E1BHL0-1|E1BHL0_BOVIN Isoform 1 of CCR4-NOT transcription complex subunit 11 OS=Bos taurus OX=9913 GN=CNOT11 PE=3 SV=1 CANONICAL=E1BHL0-1" }, "locus": { "chromosome": "11", "start_pos": 6177872, "end_pos": 6164670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010879.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010879.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010879.4", "url": "https://www.ensembl.org/id/ENSBTAP00000010879.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 179, "start_aa": "Thr", "end_pos": 179, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:506268", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506268", "resource": "KEGG Pathway" }, { "id": "R-BTA-429947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-429947", "resource": "Reactome", "description": "Deadenylation of mRNA" }, { "id": "R-BTA-6804115", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804115", "resource": "Reactome", "description": "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PEY3-1", "protein_name": "CCR4-NOT transcription complex subunit 11", "gene_name": "CNOT11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPGGGGSPAEAGGEAGGGGGAAGGRMSLSPKELTSLLGIVSEEAGGSTFEGLSSAFHHYFGKAEHFRLGSVLVLLLQQPDLLPSPAQRLTALYLLWEMYRTEPLAANPFAAVFAHLLNPAPERGGDEAERTPLSGFLPPITPPEKFFLSQLMLAPPRELFKKTPRQIAAMDVGNMAQSVDISGLQLALAERQSELPTQSKASFPSILSDPDPDSSNSGFDSSVASQITEALVSGPKPPIESHFRPEFIRPPPPLHICEDELAWLNPIEPDHTIQWDKSMCVKNSTGVEIKRIMAKAFKSPLTSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGENPSETKTSK", "length": 473 }, "evidence": [ { "id": "E1BHL0", "url": "https://omabrowser.org/oma/group/E1BHL0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A4QP78-1", "protein_name": "CCR4-NOT transcription complex subunit 11", "gene_name": "cnot11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLAPKDLSNLLGIMSEDACSSSFEQLSSAFHHCFGKAEHFGVGSVLVMLLQQPDLLPSAPQRLTALYLLWEMYRTEPLAANPFAAVFAHLLNPSSAAEEQEKTLSGFLPPITLPEKFFLSQLMLAPPRELFKKTPRQVSCMDITSTPQTIDISGLQLALAERQSELPTQSKASFPSLLSDPDPDSSNSGFDSSVANQITESLVTGPRPPLESHFRPEFIRPTPPLLVCEDELCWLNPCEPEHRVQWDRSMCVRNGTGVEIKRIMAKAFKSPLSAAQQTQLLGELEKDLKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMSSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDNGETPAEGKTSK", "length": 445 }, "evidence": [ { "id": "E1BHL0", "url": "https://omabrowser.org/oma/group/E1BHL0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B0BNA9-1", "protein_name": "CCR4-NOT transcription complex subunit 11", "gene_name": "Cnot11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGGGASTASGRLLSADPRGAREAAAFRSGPAGSSGGRGGAGGPGSGSGGPAGRMSLTPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPPRELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDPDSSNSAFDSSVASRITESLVSGPKPPIESHFRPEFIRPPPPLHICEDELAWLNPTEPEHAIQWDRSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGETPSETKVSK", "length": 504 }, "evidence": [ { "id": "E1BHL0", "url": "https://omabrowser.org/oma/group/E1BHL0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1STG2-1", "protein_name": "CCR4-NOT transcription complex subunit 11", "gene_name": "CNOT11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGGGASAASGRLFTAAEQRGTREGAGSASRCGPGVSGSGSGRGGAGVPGPGSGGPGGPAGRMSLTPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPPRELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDPDSSNSGFDSSVASQITEALVSGPKPPIESHFRPEFIRPPPPLHICEDELAWLNPTEPDHTIQWDRSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGEAPSETKMSK", "length": 512 }, "evidence": [ { "id": "E1BHL0", "url": "https://omabrowser.org/oma/group/E1BHL0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9CWN7-1", "protein_name": "CCR4-NOT transcription complex subunit 11", "gene_name": "Cnot11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGGGASTASGRLLSSADPRGAREAAAFRSGPAGSSGGRGGAGGPGPGIGGPAGRMSLTPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPPRELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDPDSSNSGFDSSVASRITESLVSGPKPPIESHFRPEFIRPPPPLHICEDELAWLNPTEPEHAIQWDRSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGETPSETKISK", "length": 505 }, "evidence": [ { "id": "E1BHL0", "url": "https://omabrowser.org/oma/group/E1BHL0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKZ1-1", "protein_name": "CCR4-NOT transcription complex subunit 11", "gene_name": "CNOT11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGGGASAASGRLLTAAEQRGSREAAGSASRSGFGGSGGGRGGASGPGSGSGGPGGPAGRMSLTPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPPRELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDPDSSNSGFDSSVASQITEALVSGPKPPIESHFRPEFIRPPPPLHICEDELAWLNPTEPDHAIQWDKSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGETPSETKMSK", "length": 510 }, "evidence": [ { "id": "E1BHL0", "url": "https://omabrowser.org/oma/group/E1BHL0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BHL0", "url": "https://www.uniprot.org/uniprotkb/E1BHL0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BHL0", "url": "https://www.uniprot.org/uniprotkb/E1BHL0" } ], "pmid": "" }, { "name": "CCR4-NOT complex", "id": "GO:0030014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030014", "evidence": [ { "database": "UniProtKB", "id": "E1BHL0", "url": "https://www.uniprot.org/uniprotkb/E1BHL0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BHL0", "url": "https://www.uniprot.org/uniprotkb/E1BHL0" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "E1BHL0", "url": "https://www.uniprot.org/uniprotkb/E1BHL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHL0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 511, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHL0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHL0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL0" }, { "id": "PF10155", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10155" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCR4-NOT transcription complex subunit 11 C-terminal", "eco_id": "ECO_0000259", "start_pos": 372, "end_pos": 496, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 179 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 321, "end_pos": 323 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHL6-1", "uniprot_ac": "E1BHL6", "uniprot_id": "E1BHL6_BOVIN", "mass": { "chemical_mass": 49243.0, "monoisotopic_mass": 49243.0 }, "refseq": { "ac": "NP_001179610", "name": "pyroglutamylated RF-amide peptide receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179610" }, "gene_names": [ { "name": "QRFPR", "type": "recommended", "evidence": [ { "id": "E1BHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL6" } ] }, { "name": "GPR103", "type": "synonym", "evidence": [ { "id": "NP_001179610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179610" } ] }, { "name": "QRFPR", "type": "synonym", "evidence": [ { "id": "NP_001179610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179610" } ] } ], "protein_names": [ { "name": "Pyroglutamylated RF-amide peptide receptor", "type": "recommended", "evidence": [ { "id": "E1BHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL6/entry#names_and_taxonomy" } ] }, { "name": "AQ27", "type": "synonym", "evidence": [ { "id": "E1BHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL6/entry#names_and_taxonomy" } ] }, { "name": "G protein-coupled receptor 103", "type": "synonym", "evidence": [ { "id": "NP_001179610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179610" } ] }, { "name": "G-protein coupled receptor 103", "type": "synonym", "evidence": [ { "id": "E1BHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL6/entry#names_and_taxonomy" } ] }, { "name": "Orexigenic neuropeptide QRFP receptor", "type": "synonym", "evidence": [ { "id": "E1BHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL6/entry#names_and_taxonomy" } ] }, { "name": "SP9155", "type": "synonym", "evidence": [ { "id": "E1BHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL6/entry#names_and_taxonomy" } ] }, { "name": "pyroglutamylated RF-amide peptide receptor", "type": "synonym", "evidence": [ { "id": "NP_001179610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179610" } ] } ], "function": [ { "annotation": "Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels.", "evidence": [ { "database": "UniProtKB", "id": "E1BHL6", "url": "https://www.uniprot.org/uniprotkb/E1BHL6#function" }, { "database": "UniProtKB", "id": "ARBA00059793", "url": "https://www.uniprot.org/uniprotkb/ARBA00059793#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHL6", "url": "https://www.uniprot.org/uniprotkb/E1BHL6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "QRFPR", "url": "https://www.uniprot.org/uniprotkb/E1BHL6", "locus": { "chromosome": "6", "start_pos": 4199241, "end_pos": 4138071, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008255", "url": "https://www.ensembl.org/id/ENSBTAG00000008255" } ] } } ], "crossref": [ { "id": "E1BHL6", "url": "https://alphafold.ebi.ac.uk/entry/E1BHL6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008255", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008255", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15205", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15205", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "529752", "url": "https://www.ncbi.nlm.nih.gov/gene/529752", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:529752", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529752", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHMMIEY", "url": "https://omabrowser.org/oma/group/IHMMIEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHL6", "url": "https://www.orthodb.org/?gene=E1BHL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-389397", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-389397", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179610", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179610", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BHL6", "url": "https://www.uniprot.org/uniprotkb/E1BHL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHL6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSLNITPEQFSRLLRDHNLTREQFISLYGLRPLVYTPELPGRAKLAFVLTGVLIFALALFGNSLVVYVVTRSKTMRTVTNIFICSLALSDLLIAFFCIPVTMLQNISNNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNQRAFTMLGLVWLVAIIVGAPMWHVQRLEIKYDFLYEKEHVCCLEEWSSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVVMMVTVVALFAVCWAPFHIVHMMMEYSNLEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNFLSAVCYCIVKETLSPARRHGNSGITMMQKKAVFSRKGNPVEETKGEAFSDGNIEVKLCEQPEEKKHLKRHLTLFNSELSENSGLGSGH", "length": 431, "header": "tr|E1BHL6-1|E1BHL6_BOVIN Isoform 1 of Pyroglutamylated RF-amide peptide receptor OS=Bos taurus OX=9913 GN=QRFPR PE=3 SV=1 CANONICAL=E1BHL6-1" }, "isoforms": [ { "isoform_ac": "E1BHL6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHL6/entry#E1BHL6-1", "sequence": { "sequence": "MQSLNITPEQFSRLLRDHNLTREQFISLYGLRPLVYTPELPGRAKLAFVLTGVLIFALALFGNSLVVYVVTRSKTMRTVTNIFICSLALSDLLIAFFCIPVTMLQNISNNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNQRAFTMLGLVWLVAIIVGAPMWHVQRLEIKYDFLYEKEHVCCLEEWSSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVVMMVTVVALFAVCWAPFHIVHMMMEYSNLEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNFLSAVCYCIVKETLSPARRHGNSGITMMQKKAVFSRKGNPVEETKGEAFSDGNIEVKLCEQPEEKKHLKRHLTLFNSELSENSGLGSGH", "length": 431, "header": "tr|E1BHL6-1|E1BHL6_BOVIN Isoform 1 of Pyroglutamylated RF-amide peptide receptor OS=Bos taurus OX=9913 GN=QRFPR PE=3 SV=1 CANONICAL=E1BHL6-1" }, "locus": { "chromosome": "6", "start_pos": 4198237, "end_pos": 4138429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010865.6", "url": "https://www.ensembl.org/id/ENSBTAT00000010865.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010865.4", "url": "https://www.ensembl.org/id/ENSBTAP00000010865.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:529752", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529752", "resource": "KEGG Pathway" }, { "id": "R-BTA-389397", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-389397", "resource": "Reactome", "description": "Orexin and neuropeptides FF and QRFP bind to their respective receptors" }, { "id": "R-BTA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S1T5-1", "protein_name": "Pyroglutamylated RF-amide peptide receptor", "gene_name": "QRFPR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQSLNITPEQFSKLLRDHNLTREQFIALYGLRPLVYIPELPRNAKLAFVLTGVLIFVLALFGNALVVYVVIRSKAMRTVTNIFICSLAVSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAIVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIIGSPMWHVQRLEIKYDFLYEKEHVCCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVIHMMIEYSNFEKEYTDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNFLSAVCYCVVKETSSPARRHGNSGITMMQKKAKFSRKENIIQETKGDAFSDGSIEVKLCEQPKEKKHLKRHLALFNSEFSENSALGSGP", "length": 431 }, "evidence": [ { "id": "E1BHL6", "url": "https://omabrowser.org/oma/group/E1BHL6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P83858-1", "protein_name": "Pyroglutamylated RF-amide peptide receptor", "gene_name": "Qrfpr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQALNITAEQFSRLLSAHNLTREQFIHRYGLRPLVYTPELPARAKVAFALAGALIFALALFGNSLVIYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPVTMLQNISDKWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTTRRAFTILGVVWLAAIIVGSPMWHVQRLEIKYDFLYEKEHICCLEEWASPVHQRIYSTFILVILFLLPLVVMLVLYSKIGYELWIKKRVGDSSALQTIHGKEMSKIARKKKRAVIMMVTVVALFAACWAPFHVVHMMVEYSNFEKEYDDVTIKMVFAVAQTIGFFNSICNPFVYAFMNENFKKNFLSAVCYCIVKESSSPARKPGNSGISMMQKRAKLSRPQRPVEETKGDTFSDASIDVKLCEQPREKRQLKRQLAFFSSELSENSTFGSGHEL", "length": 433 }, "evidence": [ { "id": "E1BHL6", "url": "https://omabrowser.org/oma/group/E1BHL6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83861-1", "protein_name": "Pyroglutamylated RF-amide peptide receptor", "gene_name": "Qrfpr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQALNITAEQFSRLLSAHNLTREQFIHRYGLRPLVYTPELPARAKLAFALAGALIFALALFGNSLVIYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPVTMLQNISDKWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLIHPFKMKWQYTTRRAFTILGVVWLAAIIVGSPMWHVQRLEIKYDFLYEKEHVCCLEEWASPMHQRIYTTFILVILFLLPLVVMLVLYSKIGYELWIKKRVGDSSALQTIHGKEMSKIARKKKRAVVMMVTVVALFAACWAPFHVVHMMVEYSNFEKEYDDVTIKMVFAVAQTIGFFNSICNPFVYAFMNENFKKNFLSAVCYCIVRETFSPGQKPGNSGISMMQKRAKLSRSQRPVAEAKGDLFSDANVDVKLCEQPGEKRQLKRQLAFFSSELSENSTFGSGHEL", "length": 433 }, "evidence": [ { "id": "E1BHL6", "url": "https://omabrowser.org/oma/group/E1BHL6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96P65-1", "protein_name": "Pyroglutamylated RF-amide peptide receptor", "gene_name": "QRFPR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSELAENSPLDSGH", "length": 431 }, "evidence": [ { "id": "E1BHL6", "url": "https://omabrowser.org/oma/group/E1BHL6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BHL6", "url": "https://www.uniprot.org/uniprotkb/E1BHL6" } ], "pmid": "" }, { "name": "neuropeptide Y receptor activity", "id": "GO:0004983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004983", "evidence": [ { "database": "UniProtKB", "id": "E1BHL6", "url": "https://www.uniprot.org/uniprotkb/E1BHL6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BHL6", "url": "https://www.uniprot.org/uniprotkb/E1BHL6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "E1BHL6", "url": "https://www.uniprot.org/uniprotkb/E1BHL6" } ], "pmid": "" }, { "name": "cellular response to hormone stimulus", "id": "GO:0032870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032870", "evidence": [ { "database": "UniProtKB", "id": "E1BHL6", "url": "https://www.uniprot.org/uniprotkb/E1BHL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHL6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 431, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHL6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHL6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 332, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHM0-1", "uniprot_ac": "E1BHM0", "uniprot_id": "E1BHM0_BOVIN", "mass": { "chemical_mass": 24255.0, "monoisotopic_mass": 24255.0 }, "refseq": { "ac": "XP_010803863", "name": "C-type lectin domain family 4 member E isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010803863" }, "gene_names": [ { "name": "CLEC4E", "type": "recommended", "evidence": [ { "id": "E1BHM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHM0" } ] }, { "name": "CLEC4E", "type": "synonym", "evidence": [ { "id": "XP_010803863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010803863" } ] } ], "protein_names": [ { "name": "C-type lectin domain family 4 member E isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010803863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010803863" } ] }, { "name": "C-type lectin domain family 4 member E", "type": "synonym", "evidence": [ { "id": "E1BHM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHM0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHM0", "url": "https://www.uniprot.org/uniprotkb/E1BHM0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CLEC4E", "url": "https://www.uniprot.org/uniprotkb/E1BHM0", "locus": { "chromosome": "5", "start_pos": 101699101, "end_pos": 101709551, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012185", "url": "https://www.ensembl.org/id/ENSBTAG00000012185" } ] } } ], "crossref": [ { "id": "E1BHM0", "url": "https://alphafold.ebi.ac.uk/entry/E1BHM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012185", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012185", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514797", "url": "https://www.ncbi.nlm.nih.gov/gene/514797", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "4KZV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=4KZV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "4KZW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=4KZW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "4ZRV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=4ZRV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "4ZRW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=4ZRW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "5KTH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5KTH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "5KTI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5KTI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8H4V", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8H4V&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8HB5", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8HB5&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514797", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514797", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BHM0", "url": "https://www.orthodb.org/?gene=E1BHM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22803", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22803", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00004kzv", "url": "https://www.rcsb.org/structure/pdb_00004kzv", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00004kzw", "url": "https://www.rcsb.org/structure/pdb_00004kzw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00004zrv", "url": "https://www.rcsb.org/structure/pdb_00004zrv", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00004zrw", "url": "https://www.rcsb.org/structure/pdb_00004zrw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00005kth", "url": "https://www.rcsb.org/structure/pdb_00005kth", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00005kti", "url": "https://www.rcsb.org/structure/pdb_00005kti", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008h4v", "url": "https://www.rcsb.org/structure/pdb_00008h4v", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008hb5", "url": "https://www.rcsb.org/structure/pdb_00008hb5", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4KZV", "url": "https://www.rcsb.org/structure/4KZV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4KZW", "url": "https://www.rcsb.org/structure/4KZW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4ZRV", "url": "https://www.rcsb.org/structure/4ZRV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4ZRW", "url": "https://www.rcsb.org/structure/4ZRW", 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"Protein Classification", "Other" ] }, { "id": "NP_001193490", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193490", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BHM1", "url": "https://www.uniprot.org/uniprotkb/E1BHM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHM1-1", "url": "https://www.uniprot.org/uniprotkb/E1BHM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEAEVGGGGAAGDKGPGEAATSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQNIGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFILPEEIIQEVREGKVIIEEEMKEEMKEDVDPHNGADDVFSSSGSLGKATEKSSKDKEKNNSDLGSKEGPDKRKRSRVTDKVLTANSNPSSPSAAKRRRT", "length": 204, "header": "tr|E1BHM1-1|E1BHM1_BOVIN Isoform 1 of MRG domain binding protein OS=Bos taurus OX=9913 GN=MRGBP PE=3 SV=3 CANONICAL=E1BHM1-1" }, "isoforms": [ { "isoform_ac": "E1BHM1-1", "url": "https://www.uniprot.org/uniprotkb/E1BHM1/entry#E1BHM1-1", "sequence": { "sequence": 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"uniprot_canonical_ac": "A0A287AUF7-1", "protein_name": "MRG domain binding protein", "gene_name": "MRGBP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGEAEVGGGGAAGDKGPGEAATSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQNIGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFVLPEEIIQEVREGKVTVEEEMKEEMKEDVDPHNGADDVFSSSGSLGKSAEKSSKDKDKSNSDLGSKEGSDKRKRSRVTDKVLTANSNPSSPSAAKRRRT", "length": 204 }, "evidence": [ { "id": "E1BHM1", "url": "https://omabrowser.org/oma/group/E1BHM1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1NRH0-1", "protein_name": "MRG domain binding protein", "gene_name": "MRGBP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGEAEGGAAAAVEKPPLPAAGPGTAAAVAAAAAAVAAAAAAAASAPEPGVPAEEAVVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQNIGRQISSKVIWDHLSTMYDMQALHESEILPFPNIEKNFILPDELIQEVREGKVMIEEEVKEEIKEEMETHTGPEEVFAPSGSLGKTTEKPSSKEKEKTSSDSGSKEGSDKRKRNRVTEKVLNANSNPSSPSAAKRRRT", "length": 233 }, "evidence": [ { "id": "E1BHM1", "url": "https://omabrowser.org/oma/group/E1BHM1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3V751-1", "protein_name": "MRG domain binding protein", "gene_name": "Mrgbp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEAEVGGTGAPGDKGPGEAAPSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQNIGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFVLPDEIIQEVREGKVVIEEEMKEEMKEDVDPHSGADDVFSSSGSLGKALEKSSKDKEKNSSDLGCKEGADKRKRSRVTDKVLTANSNPSSPSAAKRRRT", "length": 204 }, "evidence": [ { "id": "E1BHM1", "url": "https://omabrowser.org/oma/group/E1BHM1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7K003-1", "protein_name": "MRG/MORF4L-binding protein", "gene_name": "MrgBP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMAKDKGLAVAGTAAPLPAALDHEWSAEEELQLFHAMEGLRPVGINKHFYMSCIVQRLSKSLNREMPSELIWRHLGTMYKLKELDDLESLPFPNEEREFSLPEQDYGTLQTKKTVEVHANEEAAEAQSAPPTAETNGKAPPATKTPVPTNSTKDGDKKPVAKPQEQLPKRPAKRTRGSMSNESISPSTTPPPVQSNKRRRI", "length": 201 }, "evidence": [ { "id": "E1BHM1", "url": "https://omabrowser.org/oma/group/E1BHM1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9DAT2-1", "protein_name": "MRG/MORF4L-binding protein", "gene_name": "Mrgbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGEAEVGGTGAPGDKGPGEAAPSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQNIGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFVLPDEIIQEVREGKVVIEEEMKEEMKEDVDPHSGADDVFSSSGSLGKALEKSSKDKEKNSSDLGCKEGADKRKRSRVTDKVLTANSNPSSPSAAKRRRT", "length": 204 }, "evidence": [ { "id": "E1BHM1", "url": "https://omabrowser.org/oma/group/E1BHM1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NV56-1", "protein_name": 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Required for the proliferation and viability of hematopoietic cells.", "evidence": [ { "database": "UniProtKB", "id": "E1BHM9", "url": "https://www.uniprot.org/uniprotkb/E1BHM9#function" }, { "database": "UniProtKB", "id": "ARBA00045649", "url": "https://www.uniprot.org/uniprotkb/ARBA00045649#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHM9", "url": "https://www.uniprot.org/uniprotkb/E1BHM9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BHM9", "locus": {} } ], "crossref": [ { "id": "E1BHM9", "url": "https://alphafold.ebi.ac.uk/entry/E1BHM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011704", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011704", "database": 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"https://www.uniprot.org/uniprotkb/E1BHM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHM9-1", "url": "https://www.uniprot.org/uniprotkb/E1BHM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNMSGRLWSKTIFAGYKRGLQNQREHTALLKIEGVYARDETEFYLGKRCAYEYKAKNNTETPGGKPNKTRVIWGKITRAHGNSGMVCAKFRSNLPAKAIGHRIRVMLYPSRI", "length": 113, "header": "tr|E1BHM9-1|E1BHM9_BOVIN Isoform 1 of Large ribosomal subunit protein eL33 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BHM9-1" }, "isoforms": [ { "isoform_ac": "E1BHM9-1", "url": "https://www.uniprot.org/uniprotkb/E1BHM9/entry#E1BHM9-1", "sequence": { "sequence": "MTNMSGRLWSKTIFAGYKRGLQNQREHTALLKIEGVYARDETEFYLGKRCAYEYKAKNNTETPGGKPNKTRVIWGKITRAHGNSGMVCAKFRSNLPAKAIGHRIRVMLYPSRI", "length": 113, "header": "tr|E1BHM9-1|E1BHM9_BOVIN Isoform 1 of Large ribosomal subunit protein eL33 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BHM9-1" }, "locus": { "chromosome": "13", "start_pos": 62630759, "end_pos": 62630421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015544.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015544.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050006.2", "url": "https://www.ensembl.org/id/ENSBTAP00000050006.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "E1BHM9", "url": "https://www.uniprot.org/uniprotkb/E1BHM9" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "E1BHM9", "url": "https://www.uniprot.org/uniprotkb/E1BHM9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "E1BHM9", "url": "https://www.uniprot.org/uniprotkb/E1BHM9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "E1BHM9", "url": "https://www.uniprot.org/uniprotkb/E1BHM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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{ "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"E1BHN5", "url": "https://www.orthodb.org/?gene=E1BHN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10270", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10270", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10270:SF313", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10270:SF313", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024855919", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855919", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BHN5", "url": "https://www.uniprot.org/uniprotkb/E1BHN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHN5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGSGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL", "length": 277, "header": "tr|E1BHN5-1|E1BHN5_BOVIN Isoform 1 of SRY-box transcription factor 21 OS=Bos taurus OX=9913 GN=SOX21 PE=4 SV=3 CANONICAL=E1BHN5-1" }, "isoforms": [ { "isoform_ac": "E1BHN5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHN5/entry#E1BHN5-1", "sequence": { "sequence": "MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGSGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL", "length": 277, "header": "tr|E1BHN5-1|E1BHN5_BOVIN Isoform 1 of SRY-box transcription factor 21 OS=Bos taurus OX=9913 GN=SOX21 PE=4 SV=3 CANONICAL=E1BHN5-1" }, "locus": { "chromosome": "12", "start_pos": 69202134, "end_pos": 69201796, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030439.5", "url": "https://www.ensembl.org/id/ENSBTAT00000030439.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030420.4", "url": "https://www.ensembl.org/id/ENSBTAP00000030420.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614121", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614121", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F2Z520-1", "protein_name": "SRY-box transcription factor 21", "gene_name": "SOX21", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL", "length": 276 }, "evidence": [ { "id": "E1BHN5", "url": "https://omabrowser.org/oma/group/E1BHN5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6RVD7-1", "protein_name": "Transcription factor Sox-21-B", "gene_name": "sox21b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W7R5-1", "protein_name": "Transcription factor SOX-21", "gene_name": "SOX21", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGAVAEHEPPHGLKAAALHGGAAGGLGPDSLLGNPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGGPYSLLDLGSKMAEISSSSSAGSALPYASSLGYPGAGGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPGPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL", "length": 280 }, "evidence": [ { "id": "E1BHN5", "url": "https://omabrowser.org/oma/group/E1BHN5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9Y651-1", "protein_name": "Transcription factor SOX-21", "gene_name": "SOX21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 335, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"NP_001180073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180073" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHP3", "url": "https://www.uniprot.org/uniprotkb/E1BHP3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PPP1R3F", "url": "https://www.uniprot.org/uniprotkb/E1BHP3", "locus": { "chromosome": "X", "start_pos": 87324338, "end_pos": 87308205, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021100", "url": "https://www.ensembl.org/id/ENSBTAG00000021100" } ] } } ], "crossref": [ { "id": "E1BHP3", "url": "https://alphafold.ebi.ac.uk/entry/E1BHP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021100", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021100", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "513859", "url": "https://www.ncbi.nlm.nih.gov/gene/513859", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513859", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513859", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NMDDNTP", "url": "https://omabrowser.org/oma/group/NMDDNTP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHP3", "url": "https://www.orthodb.org/?gene=E1BHP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12307", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12307", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12307:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12307:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BHP3", "url": "https://www.uniprot.org/uniprotkb/E1BHP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHP3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARTAPVEPPLRHPAPPSLASGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAAAGQDGDGGGAEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFSLPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKVVHVRASHDGWASFCDHPARYVPRSPPGAGAGGPGAGDPILDLGLGLGPGQVSASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPIPTDAEGLLQQQQLEPQPECQGPVEAEARQLKSCMKPMRRRPNEELKMKSADDNTPAVAERPDVQETVGPLVAPTPLRPWPQMTLQVSEVTVTGRPPEEGDVTRSSPPVTFTEVPQAPAIRIPLSSSLCALGRSPRDQASGPDASEGAAGPLLEPSQRQMEATWEVSSENGRGRKEPVVGAVMDKPPGGLEVVSGLEELLGEDTIDQELEQLYQSHLSRLRAAVAAGGAGGGGEGSIDGGVSPSHPLGILTDRDLILKWPGPERALNSALAEEITLHYARLGRGVELIKDTEDPDEEGEGEEGLSIIPSSPEGDTPKESPPEILSGAPSLVSTMGDVWLPWAEGSGCNSPVALGIEGQFSGAPEKGTSKDSDSLHVSRMISGVTGSSGATEAQMEFTTELADRLISISGQEPAALVLQGRQDLSLLGPLGTEVCPSSLARPHVSPQDEGGSGPSLEPPKRSPTLADPAESMCVLPPQLWGPLTQTLGVLAVLVVVPVALNNGMSLLVLALCLSLVWFL", "length": 807, "header": "tr|E1BHP3-1|E1BHP3_BOVIN Isoform 1 of Protein phosphatase 1 regulatory subunit 3F OS=Bos taurus OX=9913 GN=PPP1R3F PE=4 SV=2 CANONICAL=E1BHP3-1" }, "isoforms": [ { "isoform_ac": "E1BHP3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHP3/entry#E1BHP3-1", "sequence": { "sequence": "MARTAPVEPPLRHPAPPSLASGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAAAGQDGDGGGAEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFSLPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKVVHVRASHDGWASFCDHPARYVPRSPPGAGAGGPGAGDPILDLGLGLGPGQVSASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPIPTDAEGLLQQQQLEPQPECQGPVEAEARQLKSCMKPMRRRPNEELKMKSADDNTPAVAERPDVQETVGPLVAPTPLRPWPQMTLQVSEVTVTGRPPEEGDVTRSSPPVTFTEVPQAPAIRIPLSSSLCALGRSPRDQASGPDASEGAAGPLLEPSQRQMEATWEVSSENGRGRKEPVVGAVMDKPPGGLEVVSGLEELLGEDTIDQELEQLYQSHLSRLRAAVAAGGAGGGGEGSIDGGVSPSHPLGILTDRDLILKWPGPERALNSALAEEITLHYARLGRGVELIKDTEDPDEEGEGEEGLSIIPSSPEGDTPKESPPEILSGAPSLVSTMGDVWLPWAEGSGCNSPVALGIEGQFSGAPEKGTSKDSDSLHVSRMISGVTGSSGATEAQMEFTTELADRLISISGQEPAALVLQGRQDLSLLGPLGTEVCPSSLARPHVSPQDEGGSGPSLEPPKRSPTLADPAESMCVLPPQLWGPLTQTLGVLAVLVVVPVALNNGMSLLVLALCLSLVWFL", "length": 807, "header": "tr|E1BHP3-1|E1BHP3_BOVIN Isoform 1 of Protein phosphatase 1 regulatory subunit 3F OS=Bos taurus OX=9913 GN=PPP1R3F PE=4 SV=2 CANONICAL=E1BHP3-1" }, "locus": { "chromosome": "X", "start_pos": 87323861, "end_pos": 87308404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028107.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028107.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028107.4", "url": "https://www.ensembl.org/id/ENSBTAP00000028107.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:513859", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513859", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AHW4-1", "protein_name": "Protein phosphatase 1, regulatory subunit 3F", "gene_name": "Ppp1r3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARTAPVEPPLRHPAPPSPVAGEPRASTEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAATGQDGGGGGADEDDDGEDGDEGEEEEEAFPDPSPLCPVPAGGGFYLVPTFSLPPAPGRLERLGRVMVELEALLPPPGAVPGGSGVWVPGGRPPVVRGLVRVLNRSFEKAVHVRASHDGWATFCDHPARYVPRSPPGAGVGGTGAGDPLLDPGLGLGPGQVSASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLPQQQQLQQLEPQPECQGPVEAEARQLKSCMKPVRRRPFEEEPRMRNSDDNTLAEHSDVRESLGPLLAPTPLRPWPQMTLQVSEVPLTRNPQEEGDIPRRNPPVAFTEVLQAPAIRILPSTRGLGGPAKDQASGPDASDRAAGPFLEPIQQQVEASWESGGCRKAPMVGAMTDEPARGLEIVSGLDELLGEDTIDQELEQLYLSHLSRLRAVAAAGGGEGCPDGGSSPSHPLGILTDRDLILKWPGPERALNSALAEEITLHYARLGCGVELIKDTEDPDDEGEGEEGLSITPSSPEGDSPKESPPEILSGARSVIATMGDVWLPWAERSRCDSPGVLGTQGQFTENAEKGMGKGTNPLHMNRVIVGATRSPGEAGTESQMEVPTEQESGLIAMSEKELPVPVQQEQRPALLDPTGTEVALSSVANPPVNSQDEEGGSLSLESPKRAPMPAAPVECACGLAPQLRGPLIQTLGVLAGLVMVPVALNSGLSLLVLVLCLFLAWFS", "length": 801 }, "evidence": [ { "id": "E1BHP3", "url": "https://omabrowser.org/oma/group/E1BHP3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZSY5-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3F", "gene_name": "PPP1R3F", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTAPVEPPLRHSAPPSPAAGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFSLPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDDNTFAMAEHPDVQESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPSSPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSEELLGEDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPSHPLGILTDRDLILKWPGPERALNSALAEEITLHYARLGRGVELIKDTEDPDDEGEGEEGLSVTPSSPEGDSPKESPPEILSGARSVVATMGDVWLPWAEGSGCDGPVVLGTEGQFIGDPEKGMGKDTSSLHMNRVIAGVTESLGEAGTEAQIEVTSEWAGSLDPISGKEPASPVLLQGQNPTLLSPLGAEVCLSSVARPHVSSQDEKDAGPSLEPPKKSPTLAVPAECVCALPPQLRGPLTQTLGVLAGLVVVPVALNSGVSLLVLALCLSLAWFS", "length": 799 }, "evidence": [ { "id": "E1BHP3", "url": "https://omabrowser.org/oma/group/E1BHP3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JIG4-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3F", "gene_name": "Ppp1r3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARTAPVEPPLRHPAPPSPAAGEPRASAEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAATGQDGGGGGADEEDDGEDGDEGEEEEEAFPDPSPPCPVPAGGGFYLVPTFSLPPALGRLERLGRVMVELEALLPPPGAVPGGSGVWVPGGRPPVVRGLVRVLNRSFEKAVHVRASHDGWATFCDHPARYVPRSPPGAGVGGTGAGDPLLDPGLGLGPGQMSASSPDDGGCTDRFAFQLPFAEGASDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLPQQQQLQQLEPQPECQGPVEAEARQLKSCMKPVRRRPFEEEPRMRSADDNTLAEHPDVRESLGPLLAPTPLRPWPQMTLQVPEVMLTSNPQEEGDIPRSNPPVAFTEVRQAPAIRILPATCGLGGPPRDQASGPDASDRAAGSFLEPTQQQVEAAWESGGGRKAPMVGALTDEPARGLEIVSGLDELLGEDTIDQELEQLYLSHLSRLRAVAAAGGGEGTSPTHALGILTDRDLILKWPGPERALNSALAEEITLHYARLGCGVELIKDTEDPDDEGEGEDGLSITPSSPEGGSPKESPPEILSGARSVIATMGDVWVPWAERSSSRCDSPVVLGTQGQFTENPEKGMGKDTKSLHLNRVIVGMSKSPGEAGTESQMEELPTERESSWVPSSEKELPLPVQQEQSPALLGPTGTEVCLSSVAKPHVNSQEEEGGSLNLESPKRSPMPAAPAECACGLAPQLWGPLTQTLGVLAGLVMVPVALNSGVSLLVLVLCLSLAWFS", "length": 799 }, "evidence": [ { "id": "E1BHP3", "url": "https://omabrowser.org/oma/group/E1BHP3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "protein phosphatase type 1 complex", "id": "GO:0000164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000164", "evidence": [ { "database": "UniProtKB", "id": "E1BHP3", "url": "https://www.uniprot.org/uniprotkb/E1BHP3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BHP3", "url": "https://www.uniprot.org/uniprotkb/E1BHP3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "E1BHP3", "url": "https://www.uniprot.org/uniprotkb/E1BHP3" } ], "pmid": "" }, { "name": "glycogen binding", "id": "GO:2001069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001069", "evidence": [ { "database": "UniProtKB", "id": "E1BHP3", "url": "https://www.uniprot.org/uniprotkb/E1BHP3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of glycogen biosynthetic process", "id": "GO:0005979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005979", "evidence": [ { "database": "UniProtKB", "id": "E1BHP3", "url": "https://www.uniprot.org/uniprotkb/E1BHP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHP3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 807, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHP3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHP3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP3" }, { "id": "PS51159", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBM21", "eco_id": "ECO_0000259", "start_pos": 126, "end_pos": 282, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 278, "end_pos": 280 } ] }, "class_list": [], "section_stats": [ 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHP4-1", "uniprot_ac": "E1BHP4", "uniprot_id": "E1BHP4_BOVIN", "mass": { "chemical_mass": 37973.0, "monoisotopic_mass": 37973.0 }, "refseq": { "ac": "NP_001192983", "name": "clavesin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192983" }, "gene_names": [ { "name": "CLVS2", "type": "recommended", "evidence": [ { "id": "E1BHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP4" } ] }, { "name": "CLVS2", "type": "synonym", "evidence": [ { "id": "NP_001192983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192983" } ] }, { "name": "RLBP1L2", "type": "synonym", "evidence": [ { "id": "NP_001192983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192983" } ] } ], "protein_names": [ { "name": "Clavesin-2", "type": "recommended", "evidence": [ { "id": "E1BHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP4/entry#names_and_taxonomy" } ] }, { "name": "Retinaldehyde-binding protein 1-like 2", "type": "synonym", "evidence": [ { "id": "E1BHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP4/entry#names_and_taxonomy" } ] }, { "name": "clavesin-2", "type": "synonym", "evidence": [ { "id": "NP_001192983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192983" } ] }, { "name": "retinaldehyde binding protein 1-like 2", "type": "synonym", "evidence": [ { "id": "NP_001192983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192983" } ] } ], "function": [ { "annotation": "Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).", "evidence": [ { "database": "UniProtKB", "id": "E1BHP4", "url": "https://www.uniprot.org/uniprotkb/E1BHP4#function" }, { "database": "UniProtKB", "id": "ARBA00046144", "url": "https://www.uniprot.org/uniprotkb/ARBA00046144#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHP4", "url": "https://www.uniprot.org/uniprotkb/E1BHP4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CLVS2", "url": "https://www.uniprot.org/uniprotkb/E1BHP4", "locus": { "chromosome": "9", "start_pos": 28261741, "end_pos": 28338600, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021099", "url": "https://www.ensembl.org/id/ENSBTAG00000021099" } ] } } ], "crossref": [ { "id": "E1BHP4", "url": "https://alphafold.ebi.ac.uk/entry/E1BHP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021099", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021099", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534359", "url": "https://www.ncbi.nlm.nih.gov/gene/534359", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534359", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534359", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEEPDYC", "url": "https://omabrowser.org/oma/group/DEEPDYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHP4", "url": "https://www.orthodb.org/?gene=E1BHP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10174:SF73", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10174:SF73", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-432720", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432720", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192983", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192983", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BHP4", "url": "https://www.uniprot.org/uniprotkb/E1BHP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHP4-1", "url": "https://www.uniprot.org/uniprotkb/E1BHP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYSVDSYSMPVKEVEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD", "length": 327, "header": "tr|E1BHP4-1|E1BHP4_BOVIN Isoform 1 of Clavesin-2 OS=Bos taurus OX=9913 GN=CLVS2 PE=4 SV=1 CANONICAL=E1BHP4-1" }, "isoforms": [ { "isoform_ac": "E1BHP4-1", "url": "https://www.uniprot.org/uniprotkb/E1BHP4/entry#E1BHP4-1", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYSVDSYSMPVKEVEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD", "length": 327, "header": "tr|E1BHP4-1|E1BHP4_BOVIN Isoform 1 of Clavesin-2 OS=Bos taurus OX=9913 GN=CLVS2 PE=4 SV=1 CANONICAL=E1BHP4-1" }, "locus": { "chromosome": "9", "start_pos": 28338428, "end_pos": 28262757, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028105.5", "url": "https://www.ensembl.org/id/ENSBTAT00000028105.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028105.4", "url": "https://www.ensembl.org/id/ENSBTAP00000028105.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534359", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534359", "resource": "KEGG Pathway" }, { "id": "R-BTA-432720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432720", "resource": "Reactome", "description": "Lysosome Vesicle Biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TN77-1", "protein_name": "Clavesin-2", "gene_name": "CLVS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYSMPVKDMEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD", "length": 327 }, "evidence": [ { "id": "E1BHP4", "url": "https://omabrowser.org/oma/group/E1BHP4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6JUQ6-1", "protein_name": "Clavesin-2", "gene_name": "Clvs2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYSMPVNEVDKELSPKSMKRSQSVVDPTALKRMDKSEEENMQPLLSLD", "length": 327 }, "evidence": [ { "id": "E1BHP4", "url": "https://omabrowser.org/oma/group/E1BHP4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C6S0-1", "protein_name": "Clavesin-2", "gene_name": "CLVS2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFQHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSECNVDSYNAPAKDIEKDLSPKSMKRSQSVVDPGVLKRMDKNEEENMQPLLSLD", "length": 327 }, "evidence": [ { "id": "E1BHP4", "url": "https://omabrowser.org/oma/group/E1BHP4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HKL3-1", "protein_name": "Clavesin-2", "gene_name": "Clvs2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSVVDPTALKRMDKSEEENMQPLLSLD", "length": 327 }, "evidence": [ { "id": "E1BHP4", "url": "https://omabrowser.org/oma/group/E1BHP4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5SPP0-1", "protein_name": "Clavesin-2", "gene_name": "clvs2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTHLQAGLSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNLKATDPGIKQALKDGFPGVLSNLDRYGRKILVLFAANWDQSRYTFVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLILPEILPSELGGMLPPYDMGTWARTLLDHAYDEETDYCPESYTLSVKDLEKDLSPKTMKRSQSVVEPGVLKRPEKVKSEEENMQPLLSLD", "length": 329 }, "evidence": [ { "id": "E1BHP4", "url": "https://omabrowser.org/oma/group/E1BHP4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5SYC1-1", "protein_name": "Clavesin-2", "gene_name": "CLVS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD", "length": 327 }, "evidence": [ { "id": "E1BHP4", "url": "https://omabrowser.org/oma/group/E1BHP4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BG92-1", "protein_name": "Clavesin-2", "gene_name": "Clvs2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPNMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYNMPVKDVDKELSPKSMKRSQSVVDPTALKRMDKSEEENMQPLLALD", 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"MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPGHAPGRDEAAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMTKLHMSHETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSKEAL", "length": 222 }, "evidence": [ { "id": "E1BHR6", "url": "https://omabrowser.org/oma/group/E1BHR6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BHR6", "url": "https://www.uniprot.org/uniprotkb/E1BHR6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BHR6", "url": "https://www.uniprot.org/uniprotkb/E1BHR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, 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"E1BHS2", "url": "https://www.orthodb.org/?gene=E1BHS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19290:SF171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19290:SF171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001137577", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137577", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BHS2", "url": "https://www.uniprot.org/uniprotkb/E1BHS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHS2-1", "url": "https://www.uniprot.org/uniprotkb/E1BHS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVKSETLELKEEEDVLVLLGSASPASAALTPVSSSADEEEEEELGAAGGARRQLGAEAGPAALGGSPGGAEGCRPARLLGVVHECKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGSLPGALFSEAVILSPGGTSAALSNSGDSPSPASTWSCTNSPAESSSASSNSTSPYSCTLSPASPEGSDMDYWQPPPPDKHRYAPHLPIVRDCI", "length": 270, "header": "tr|E1BHS2-1|E1BHS2_BOVIN Isoform 1 of Neurogenin 2 OS=Bos taurus OX=9913 GN=NEUROG2 PE=4 SV=2 CANONICAL=E1BHS2-1" }, "isoforms": [ { "isoform_ac": "E1BHS2-1", "url": "https://www.uniprot.org/uniprotkb/E1BHS2/entry#E1BHS2-1", "sequence": { "sequence": "MFVKSETLELKEEEDVLVLLGSASPASAALTPVSSSADEEEEEELGAAGGARRQLGAEAGPAALGGSPGGAEGCRPARLLGVVHECKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGSLPGALFSEAVILSPGGTSAALSNSGDSPSPASTWSCTNSPAESSSASSNSTSPYSCTLSPASPEGSDMDYWQPPPPDKHRYAPHLPIVRDCI", "length": 270, "header": "tr|E1BHS2-1|E1BHS2_BOVIN Isoform 1 of Neurogenin 2 OS=Bos taurus OX=9913 GN=NEUROG2 PE=4 SV=2 CANONICAL=E1BHS2-1" }, "locus": { "chromosome": "6", "start_pos": 13068316, "end_pos": 13067507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020291.5", "url": "https://www.ensembl.org/id/ENSBTAT00000020291.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020291.4", "url": "https://www.ensembl.org/id/ENSBTAP00000020291.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:615555", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615555", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AMU8-1", "protein_name": "Neurogenin 2", "gene_name": "NEUROG2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFVKSETLELKEEEDVLVLLRSASPASAALTPLSSSTDEEEEEELRSSGGASRPRGAEAGPGAQGRSPGGTEGCRPARLLGLVHECKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGGLPGALFSEAVLLSPGGSSAALSSSGDSPSPASTWSCTNSPAPSSSASSNSTSPYSCTLSPASPAGSDMDYWQSPPPDKHRYASHLPIVRDCI", "length": 272 }, "evidence": [ { "id": "E1BHS2", "url": "https://omabrowser.org/oma/group/E1BHS2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LKE1-1", "protein_name": "Neurogenin 2", "gene_name": "Neurog2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFVKSETLELKEEEEVLMLLGSASPASATLTPMSSSADEEEDEELRRPGAARGQRGAEAGQGVQGSSASGAGGCRPGRLLGLVHECKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCAGGGSLQGALFSEAVLLSPGAALGASGDSPSPSSSWSCTNSPASSSNSTSPYSCTLSPASPGSDVDYWQPPPPEKHRYAPHLPLARDCI", "length": 263 }, "evidence": [ { "id": "E1BHS2", "url": "https://omabrowser.org/oma/group/E1BHS2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H2A3-1", "protein_name": "Neurogenin-2", "gene_name": "NEUROG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFVKSETLELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSPASPAGSDMDYWQPPPPDKHRYAPHLPIARDCI", "length": 272 }, "evidence": [ { "id": "E1BHS2", "url": "https://omabrowser.org/oma/group/E1BHS2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9YH82-1", "protein_name": "Neurogenin 2", "gene_name": "NEUROG2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPVKAESPAPAAEDELLLLRLASPAPSASLPSSAGEEDEDEEDGRPRRLQEGARRAGRQRGPPRAARTAETAQRIKRSRRLKANNRERNRMHNLNAALDALRDVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLAGAARLGGAADAAPGAAAEGSPSPASSWSGGASPAPSASPYACTLSPGSPAGSASDAEHWPPPRGRFAPPPPPHRCL", "length": 213 }, "evidence": [ { "id": "E1BHS2", "url": "https://omabrowser.org/oma/group/E1BHS2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BHS2", "url": "https://www.uniprot.org/uniprotkb/E1BHS2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BHS2", "url": "https://www.uniprot.org/uniprotkb/E1BHS2" } ], "pmid": "" }, { "name": "forebrain development", "id": "GO:0030900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030900", "evidence": [ { "database": "UniProtKB", "id": "E1BHS2", "url": "https://www.uniprot.org/uniprotkb/E1BHS2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BHS2", "url": "https://www.uniprot.org/uniprotkb/E1BHS2" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "E1BHS2", "url": "https://www.uniprot.org/uniprotkb/E1BHS2" } ], "pmid": "" }, { "name": "sensory organ development", "id": "GO:0007423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007423", "evidence": [ { "database": "UniProtKB", "id": "E1BHS2", "url": "https://www.uniprot.org/uniprotkb/E1BHS2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "E1BHS2", "url": "https://www.uniprot.org/uniprotkb/E1BHS2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BHS2", "url": "https://www.uniprot.org/uniprotkb/E1BHS2" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "E1BHS2", "url": "https://www.uniprot.org/uniprotkb/E1BHS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHS2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 270, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHS2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHS2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHS2" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 164, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHU5-1", "uniprot_ac": "E1BHU5", "uniprot_id": "E1BHU5_BOVIN", "mass": { "chemical_mass": 53642.0, "monoisotopic_mass": 53642.0 }, "refseq": { "ac": "NP_001178153", "name": "zinc finger and BTB domain-containing protein 32", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178153" }, "gene_names": [ { "name": "ZBTB32", "type": "recommended", "evidence": [ { "id": "E1BHU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" } ] }, { "name": "ZBTB32", "type": "synonym", "evidence": [ { "id": "NP_001178153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178153" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 32", "type": "recommended", "evidence": [ { "id": "E1BHU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHU5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 32", "type": "synonym", "evidence": [ { "id": "NP_001178153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178153" } ] } ], "function": [ { "annotation": "DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.", "evidence": [ { "database": "UniProtKB", "id": "E1BHU5", "url": "https://www.uniprot.org/uniprotkb/E1BHU5#function" }, { "database": "UniProtKB", "id": "ARBA00059064", "url": "https://www.uniprot.org/uniprotkb/ARBA00059064#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHU5", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZBTB32", "url": "https://www.uniprot.org/uniprotkb/E1BHU5", "locus": { "chromosome": "18", "start_pos": 46432573, "end_pos": 46428944, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000023611", "url": "https://www.ensembl.org/id/ENSBTAG00000023611" } ] } } ], "crossref": [ { "id": "E1BHU5", "url": "https://alphafold.ebi.ac.uk/entry/E1BHU5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000023611", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000023611", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "785741", "url": "https://www.ncbi.nlm.nih.gov/gene/785741", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:785741", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785741", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VWRDQRI", "url": "https://omabrowser.org/oma/group/VWRDQRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHU5", "url": "https://www.orthodb.org/?gene=E1BHU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178153", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178153", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BHU5", "url": "https://www.uniprot.org/uniprotkb/E1BHU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHU5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLSPTRLPSPYASDRLVRLAARLRPALCDTLITVGSQEFPAHSLVLAGVSQQLGRRGRWAVVKGISPSTFAQLLHFVYGESLELHPGELGPLEEAARTLGVQSLEEACFRARRDMAREELGPGLKKQEELEKPTRDSMRGVGAFGEKQRPEKFVRAGGKEQETLHRPRPPRESPDTAEAILEGRGEQMRPKEQLHQALVGHGRVGGKQEVVMWLRDSARGSEESLREFPGPLPPAGSFQTGITPSPWWAEAPWLGEGQSALWSILLLPPRYGTPFSHSIPMTGAWQEVWPPDQRIPLSLNLHKGLWSQNQLASSSPTPGSLPQVPTQLSPGETEESDQRRTGELATCVGQVGTASHPSLPHPPPPTPARSRPYSCSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRCPLCQAGCPSLASMQAHMRGHSPSQLPPGWTIRSTFLYSSSSRPSRASTSPSRPSSSTT", "length": 489, "header": "tr|E1BHU5-1|E1BHU5_BOVIN Isoform 1 of Zinc finger and BTB domain-containing protein 32 OS=Bos taurus OX=9913 GN=ZBTB32 PE=3 SV=1 CANONICAL=E1BHU5-1" }, "isoforms": [ { "isoform_ac": "E1BHU5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHU5/entry#E1BHU5-1", "sequence": { "sequence": "MPLSPTRLPSPYASDRLVRLAARLRPALCDTLITVGSQEFPAHSLVLAGVSQQLGRRGRWAVVKGISPSTFAQLLHFVYGESLELHPGELGPLEEAARTLGVQSLEEACFRARRDMAREELGPGLKKQEELEKPTRDSMRGVGAFGEKQRPEKFVRAGGKEQETLHRPRPPRESPDTAEAILEGRGEQMRPKEQLHQALVGHGRVGGKQEVVMWLRDSARGSEESLREFPGPLPPAGSFQTGITPSPWWAEAPWLGEGQSALWSILLLPPRYGTPFSHSIPMTGAWQEVWPPDQRIPLSLNLHKGLWSQNQLASSSPTPGSLPQVPTQLSPGETEESDQRRTGELATCVGQVGTASHPSLPHPPPPTPARSRPYSCSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRCPLCQAGCPSLASMQAHMRGHSPSQLPPGWTIRSTFLYSSSSRPSRASTSPSRPSSSTT", "length": 489, "header": "tr|E1BHU5-1|E1BHU5_BOVIN Isoform 1 of Zinc finger and BTB domain-containing protein 32 OS=Bos taurus OX=9913 GN=ZBTB32 PE=3 SV=1 CANONICAL=E1BHU5-1" }, "locus": { "chromosome": "18", "start_pos": 46432260, "end_pos": 46430126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032282.5", "url": "https://www.ensembl.org/id/ENSBTAT00000032282.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032217.4", "url": "https://www.ensembl.org/id/ENSBTAP00000032217.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 318, "start_aa": "Thr", "end_pos": 318, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr318", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 367, "start_aa": "Thr", "end_pos": 367, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr367", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:785741", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785741", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZXK1-1", "protein_name": "Zinc finger and BTB domain-containing protein 32", "gene_name": "ZBTB32", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLSPTRLPSPYGSDRLVRLAARLRPALCDTLITVGSQEFPAHSLVLAGVSQQLGRRGCWAVGKGISPSTFAQLLHFVYGESLELQPGELGPLEEAARVLGVQSLEEACRRAQRDPAKDELGPRLKEQQKEPEQPIGDSLRGVEGFGENQRAEMFFRAGEQEQETLHRHRRPRESPEMAETTWEGQREQMRLKEKLNQAPTGHGKQEMIMRVRDGPGGSEENLRELPGPLPPSGPLQTGITPRPWWAEAPWLGEGLPALWSILLLPPRYGTPFSHSTPITGAWQEVWPQDQRIPLSLNLHKGLWSQNQLASSSPTPGSLPQGPTALSPGEMEEADQRHTGELATCVGHVATAGHASPRHPPPRPPARSRPYSCSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRCPLCKAGCPSLASMQAHMRGHSPSQLPPGWTIRSTFLYSSSSSSRPSSST", "length": 477 }, "evidence": [ { "id": "E1BHU5", "url": "https://omabrowser.org/oma/group/E1BHU5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A2U2-1", "protein_name": "Zinc finger and BTB domain-containing protein 32", "gene_name": "Zbtb32", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQTPTRLISPYGSDRLVQLAARLRPALCDTLITVGGQEFLAHSLVLAGASPRLGCRGRWALVEGISPSTFAQLLTFVYGESVELQPGELGNLEEAARALGVQALEEACKRAQAAKNHEAGLDPGWKGHQQSEFMRSSERGLGAPAERQTPEEESSSEREQETPEEHKAPGESPEMAGGRARMRGSEEALSPASMGYRGAETKQAEVMRGRASHRGSEESLRGCSSPLSPPGSLLTSLIPRPWWAEAPWLGEGQPALWSILLWPSRYGAPFSHSTPITAAWQVWPQDQRIPLTLNHCKGLWSENQLASSSPTPGSFPQGTEKLSPWEAEESGQGYTGTLATCVSQERRLNCPSHQHPPLPSPARSRPYSCSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRCPLCRAGCPSLASMQAHMRGHSPSRLPPGWTIRSTFLYSSSRPTRASISPGSPTSSAAT", "length": 483 }, "evidence": [ { "id": "E1BHU5", "url": "https://omabrowser.org/oma/group/E1BHU5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y2Y4-1", "protein_name": "Zinc finger and BTB domain-containing protein 32", "gene_name": "ZBTB32", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLPPIRLPSPYGSDRLVQLAARLRPALCDTLITVGSQEFPAHSLVLAGVSQQLGRRGQWALGEGISPSTFAQLLNFVYGESVELQPGELRPLQEAARALGVQSLEEACWRARGDRAKKPDPGLKKHQEEPEKPSRNPERELGDPGEKQKPEQVSRTGGREQEMLHKHSPPRGRPEMAGATQEAQQEQTRSKEKRLQAPVGQRGADGKHGVLTWLRENPGGSEESLRKLPGPLPPAGSLQTSVTPRPSWAEAPWLVGGQPALWSILLMPPRYGIPFYHSTPTTGAWQEVWREQRIPLSLNAPKGLWSQNQLASSSPTPGSLPQGPAQLSPGEMEESDQGHTGALATCAGHEDKAGCPPRPHPPPAPPARSRPYACSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRCSLCGAGCPSLASMQAHMRGHSPSQLPPGWTIRSTFLYSSSRPSRPSTSPCCPSSSTT", "length": 487 }, "evidence": [ { "id": "E1BHU5", "url": "https://omabrowser.org/oma/group/E1BHU5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BHU5", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BHU5", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "E1BHU5", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "E1BHU5", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BHU5", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BHU5", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BHU5", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BHU5", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHU5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 489, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHU5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHU5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 87, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BHU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHU5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 374, "end_pos": 401, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 318, 367 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHV3-1", "uniprot_ac": "E1BHV3", "uniprot_id": "E1BHV3_BOVIN", "mass": { "chemical_mass": 66084.0, "monoisotopic_mass": 66084.0 }, "refseq": { "ac": "XP_002698030", "name": "acyl-coenzyme A synthetase ACSM5, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698030" }, "gene_names": [ { "name": "ACSM5", "type": "recommended", "evidence": [ { "id": "E1BHV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" } ] }, { "name": "ACSM5", "type": "synonym", "evidence": [ { "id": "XP_002698030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698030" } ] } ], "protein_names": [ { "name": "medium-chain acyl-CoA ligase", "type": "recommended", "evidence": [ { "id": "E1BHV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV3/entry#names_and_taxonomy" } ] }, { "name": "6.2.1.2", "type": "synonym", "evidence": [ { "id": "E1BHV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV3/entry#names_and_taxonomy" } ] }, { "name": "acyl-coenzyme A synthetase ACSM5, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002698030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698030" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHV3", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ACSM5", "url": "https://www.uniprot.org/uniprotkb/E1BHV3", "locus": { "chromosome": "25", "start_pos": 18120055, "end_pos": 18089282, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000037449", "url": "https://www.ensembl.org/id/ENSBTAG00000037449" } ] } } ], "crossref": [ { "id": "E1BHV3", "url": "https://alphafold.ebi.ac.uk/entry/E1BHV3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000037449", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000037449", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100298888", "url": "https://www.ncbi.nlm.nih.gov/gene/100298888", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100298888", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100298888", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PFNWALD", "url": "https://omabrowser.org/oma/group/PFNWALD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR43605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43605:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43605:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002698030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698030", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "48340", "url": "https://www.rhea-db.org/rhea/48340", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BHV3", "url": "https://www.uniprot.org/uniprotkb/E1BHV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHV3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLWLKELVLQALRNARGICGSHGQPPPLPVPQKIVATWEAISLGRQPVPEYFNFAHDVLDVWSQLEKAGHRPPIPAFWWVDGTGAEVKWSFEELGEQSRKAANVLEGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGAIMIPGISQLTEKDLKFRLQASRAKAIITSDSLAPRVDAISADCPSLQTKLLVSDSYRPGWMNFRELLWEAATEHNCARTRGQDPVAIYFTSGTTGTPKMVEHTQASYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHELPRFDAKFILNTLSRFPITTLCCVPTMFRLLVQEDLTRYQFQSLRHCVTGGEALTPDVREKWKSQTGLELHEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQVVDEEGNILPPGEEGNVAIRVRPTRPFCFFTCYLDNPEKTAASERGDFYITGDRAHMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLSPAYSSHDPEKLTQELQEHVKRVTAPYKYPRKMAFVSELPKTVSGKIQRSKLRSQEWKNEKQPQKGPISH", "length": 590, "header": "tr|E1BHV3-1|E1BHV3_BOVIN Isoform 1 of medium-chain acyl-CoA ligase OS=Bos taurus OX=9913 GN=ACSM5 PE=3 SV=4 CANONICAL=E1BHV3-1" }, "isoforms": [ { "isoform_ac": "E1BHV3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHV3/entry#E1BHV3-1", "sequence": { "sequence": "MRLWLKELVLQALRNARGICGSHGQPPPLPVPQKIVATWEAISLGRQPVPEYFNFAHDVLDVWSQLEKAGHRPPIPAFWWVDGTGAEVKWSFEELGEQSRKAANVLEGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGAIMIPGISQLTEKDLKFRLQASRAKAIITSDSLAPRVDAISADCPSLQTKLLVSDSYRPGWMNFRELLWEAATEHNCARTRGQDPVAIYFTSGTTGTPKMVEHTQASYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHELPRFDAKFILNTLSRFPITTLCCVPTMFRLLVQEDLTRYQFQSLRHCVTGGEALTPDVREKWKSQTGLELHEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQVVDEEGNILPPGEEGNVAIRVRPTRPFCFFTCYLDNPEKTAASERGDFYITGDRAHMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLSPAYSSHDPEKLTQELQEHVKRVTAPYKYPRKMAFVSELPKTVSGKIQRSKLRSQEWKNEKQPQKGPISH", "length": 590, "header": "tr|E1BHV3-1|E1BHV3_BOVIN Isoform 1 of medium-chain acyl-CoA ligase OS=Bos taurus OX=9913 GN=ACSM5 PE=3 SV=4 CANONICAL=E1BHV3-1" }, "locus": { "chromosome": "25", "start_pos": 18119051, "end_pos": 18094144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054846.5", "url": "https://www.ensembl.org/id/ENSBTAT00000054846.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049099.4", "url": "https://www.ensembl.org/id/ENSBTAP00000049099.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100298888", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100298888", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3L882-1", "protein_name": "medium-chain acyl-CoA ligase", "gene_name": "ACSM5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRLWLRGPVLQALRRVRGTCGSQGQPPPLPVPPKIVATWEAISLGRQPVPEYFNFAHDVLDVWSQLEKAGHRPPNPAFWWVDGRGAEVQWSFEELGEQSRKAANVLGGMCGLQPGDRMMLVLPRLPEWWLVSVACMRTGAVMIPGISQLTEKDLKFRLQASRAKSIITSDSLAPRVDAISADCPSLQTKLLVSDSSRPGWMNFRQLLREASSEHSCARTKSQDPLAIYFTSGTTGAPKMVEHTQASYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHELPRVDAKVILNTLSSFPITTFCCIPTIFRLLVQEDLTRYQFQSLKHCLTGGEALNPDVRGKWKSQTGLELHEGYGQSETVVICANPKGSKIKAGSMGQASPPYEVQIVDDEGNVLPPGEEGNIAIRVRPARPFCFFRCYLDNPEKTAASERGDFYITGDRAHIDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLEAAVVSSPDPIRGEVVKAFIVLSPAYTSHDPKKLTWELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEWRR", "length": 579 }, "evidence": [ { "id": "E1BHV3", "url": "https://omabrowser.org/oma/group/E1BHV3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6NUN0-1", "protein_name": "Acyl-coenzyme A synthetase ACSM5, mitochondrial", "gene_name": "ACSM5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPWLRHLVLQALRNSRAFCGSHGKPAPLPVPQKIVATWEAISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEWGK", "length": 579 }, "evidence": [ { "id": "E1BHV3", "url": "https://omabrowser.org/oma/group/E1BHV3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BGA8-1", "protein_name": "Acyl-coenzyme A synthetase ACSM5, mitochondrial", "gene_name": "Acsm5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLWLRGLACQALRSSWGVCRIHTQPPPPPIPEVVATWEAISLGRQPVPEYFNFAHDVLDVWSQLEKTGHRPPNPAFWWVNGSGTEVKWTFEELGKQSRKAANVLEGVCGLQPGDRMMLVLPRLPDWWLISVACMRTGVVMIPGVSQLTAKDLKYRLQAARAKSIVTSDALAPQVDAISADCPSLQTKLLVSDTSRPGWINFRELLRAASPEHNCVRTRSGDSVAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWMALTESDIFWNTTDTGWVKAAWTLFSAWSNGACIFVHELPRVDAKTILNTLCRFPITTLCCVPTLFRLLVQEDLTRYKFQCLRHCLTGGEALNPDVRDKWKSQTGLELHEGYGQSETVVICGNSRNSTIKSGSMGKASPPYDVQIVDEEGNVLPPGKEGNIAVRIKPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRAHMDEDGYFWFLGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLSPAYASHDPEALTRELQEHVKTVTAPYKYPRKVAFISELPKTVSGKILRSKLRNQEWGR", "length": 578 }, "evidence": [ { "id": "E1BHV3", "url": "https://omabrowser.org/oma/group/E1BHV3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M0X9-1", "protein_name": "4-coumarate--CoA ligase-like 7", "gene_name": "4CLL7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEKSGYGRDGIYRSLRPTLVLPKDPNTSLVSFLFRNSSSYPSKLAIADSDTGDSLTFSQLKSAVARLAHGFHRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTVNEVSKQIKDSNPKIIISVNQLFDKIKGFDLPVVLLGSKDTVEIPPGSNSKILSFDNVMELSEPVSEYPFVEIKQSDTAALLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLAVITYSQLQRGNALVSMARFELELVLKNIEKFRVTHLWVVPPVFLALSKQSIVKKFDLSSLKYIGSGAAPLGKDLMEECGRNIPNVLLMQGYGMTETCGIVSVEDPRLGKRNSGSAGMLAPGVEAQIVSVETGKSQPPNQQGEIWVRGPNMMKGYLNNPQATKETIDKKSWVHTGDLGYFNEDGNLYVVDRIKELIKYKGFQVAPAELEGLLVSHPDILDAVVIPFPDEEAGEVPIAFVVRSPNSSITEQDIQKFIAKQVAPYKRLRRVSFISLVPKSAAGKILRRELVQQVRSKM", "length": 544 }, "evidence": [ { "id": "E1BHV3", "url": "https://omabrowser.org/oma/group/E1BHV3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BHV3", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BHV3", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" } ], "pmid": "" }, { "name": "medium-chain fatty acid-CoA ligase activity", "id": "GO:0031956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031956", "evidence": [ { "database": "UniProtKB", "id": "E1BHV3", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BHV3", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "E1BHV3", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48340", "name": "", "equation": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5R6-1", "E1BHV3-1", "G3N2S1-1", "F1MES1-1", "F1MPP7-1", "Q9BEA2-1", "Q17QJ1-1" ], "evidence": [ { "id": "48340", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48340" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9S5R6", "gene_name": "ACSM2B", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0AAA9S5R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5R6" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "A0AAA9S5R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5R6" } ] } ] }, { "uniprot_ac": "E1BHV3", "gene_name": "ACSM5", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "E1BHV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "E1BHV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" } ] } ] }, { "uniprot_ac": "F1MES1", "gene_name": "ACSM3", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "F1MES1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MES1" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "F1MES1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MES1" } ] } ] }, { "uniprot_ac": "F1MPP7", "gene_name": "ACSM1", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "F1MPP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPP7" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "F1MPP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPP7" } ] } ] }, { "uniprot_ac": "G3N2S1", "gene_name": "ACSM4", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "G3N2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "G3N2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ] } ] }, { "uniprot_ac": "Q17QJ1", "gene_name": "ACSF2", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "Q17QJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ1" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "Q17QJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ1" } ] } ] }, { "uniprot_ac": "Q9BEA2", "gene_name": "ACSM1", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "Q9BEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9BEA2" } ] }, { "ec_number": "6.2.1.25", "activity": "benzoate + ATP + CoA = benzoyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "Q9BEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9BEA2" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "Q9BEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9BEA2" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BHV3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 590, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BHV3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BHV3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" }, { "id": "PF13193", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13193" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AMP-binding enzyme C-terminal", "eco_id": "ECO_0000259", "start_pos": 486, "end_pos": 566, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BHV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" }, { "id": "PF00501", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AMP-dependent synthetase/ligase", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 422, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.2.1.2", "ec_name": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "6.2.1.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.2" }, { "id": "6.2.1.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.2.1.2" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 }, { "start_pos": 288, "end_pos": 290 }, { "start_pos": 476, "end_pos": 478 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BHV8-1", "uniprot_ac": "E1BHV8", "uniprot_id": "E1BHV8_BOVIN", "mass": { "chemical_mass": 34928.0, "monoisotopic_mass": 34928.0 }, "refseq": { "ac": "NP_001376848", "name": "olfactory receptor family 8 subfamily B member 12", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376848" }, "gene_names": [ { "name": "OR8B12", "type": "recommended", "evidence": [ { "id": "E1BHV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV8" } ] }, { "name": "OR8B12", "type": "synonym", "evidence": [ { "id": "NP_001376848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376848" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BHV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 145", "type": "synonym", "evidence": [ { "id": "NP_001376848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376848" } ] }, { "name": "olfactory receptor family 8 subfamily B member 12", "type": "synonym", "evidence": [ { "id": "NP_001376848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376848" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"https://www.ncbi.nlm.nih.gov/protein/XP_005215660" } ] } ], "protein_names": [ { "name": "Dendrocyte expressed seven transmembrane protein", "type": "synonym", "evidence": [ { "id": "E1BI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI32/entry#names_and_taxonomy" } ] }, { "name": "dendritic cell-specific transmembrane protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005215660", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215660" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BI32", "url": "https://www.uniprot.org/uniprotkb/E1BI32" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DCSTAMP", "url": "https://www.uniprot.org/uniprotkb/E1BI32", "locus": { "chromosome": "14", "start_pos": 60265369, "end_pos": 60283557, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021240", "url": "https://www.ensembl.org/id/ENSBTAG00000021240" } ] } } ], "crossref": [ { "id": "E1BI32", "url": "https://alphafold.ebi.ac.uk/entry/E1BI32", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021240", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021240", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "512133", "url": "https://www.ncbi.nlm.nih.gov/gene/512133", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512133", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512133", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CFKHLRC", "url": "https://omabrowser.org/oma/group/CFKHLRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BI32", "url": "https://www.orthodb.org/?gene=E1BI32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21041", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21041", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21041:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21041:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005215660", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215660", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BI32", "url": "https://www.uniprot.org/uniprotkb/E1BI32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI32-1", "url": "https://www.uniprot.org/uniprotkb/E1BI32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVWTSGGNIFLSLWGTYVSPRSPGWMAFAQHAGVCCFVSFISVGLLSGAFYWFLSSLTVFITSWMATCVLLCCSKHARCFILLFFLSCGLREGRNALIAAGTGVVIFGHVENIFHNFKGLLDSMTCNLRAKSFAIHFPLLKKYIEAIRWVYGLVTHLSLFDDLVSWNQTLEVSLFSPSQALEAQLNDTTDKALGVLYQMVMATEVLCSLGRQLLALTGLLLVLLGTGLFMKRFLDPCGWKFENIYLTRHFVQLDERERREQRPCVLPLNKQERKKYVVIPSFWLTPKDRRNLGLFFLPVLTHLYIWLLFAAIDYLLYSLIFSMSKHFQSLPGLEVRLKLHRQEQGTQDIIHASSFNISLFEPTCIPKPKLLLSKTWIPLSIILVILVTLGLLSSVLMQLKILVSASFYPSVQRERMQYLHAKILKKRSKRPVGEVKGKLSLYFTKIHFWLPVLKMIGKKQMDIASEDNPEETPHSSSSTLCQQSFSSLQMAALPHPQQERTAQQDPSAA", "length": 510, "header": "tr|E1BI32-1|E1BI32_BOVIN Isoform 1 of Dendrocyte expressed seven transmembrane protein OS=Bos taurus OX=9913 GN=DCSTAMP PE=4 SV=2 CANONICAL=E1BI32-1" }, "isoforms": [ { "isoform_ac": "E1BI32-1", "url": "https://www.uniprot.org/uniprotkb/E1BI32/entry#E1BI32-1", "sequence": { "sequence": "MGVWTSGGNIFLSLWGTYVSPRSPGWMAFAQHAGVCCFVSFISVGLLSGAFYWFLSSLTVFITSWMATCVLLCCSKHARCFILLFFLSCGLREGRNALIAAGTGVVIFGHVENIFHNFKGLLDSMTCNLRAKSFAIHFPLLKKYIEAIRWVYGLVTHLSLFDDLVSWNQTLEVSLFSPSQALEAQLNDTTDKALGVLYQMVMATEVLCSLGRQLLALTGLLLVLLGTGLFMKRFLDPCGWKFENIYLTRHFVQLDERERREQRPCVLPLNKQERKKYVVIPSFWLTPKDRRNLGLFFLPVLTHLYIWLLFAAIDYLLYSLIFSMSKHFQSLPGLEVRLKLHRQEQGTQDIIHASSFNISLFEPTCIPKPKLLLSKTWIPLSIILVILVTLGLLSSVLMQLKILVSASFYPSVQRERMQYLHAKILKKRSKRPVGEVKGKLSLYFTKIHFWLPVLKMIGKKQMDIASEDNPEETPHSSSSTLCQQSFSSLQMAALPHPQQERTAQQDPSAA", "length": 510, "header": "tr|E1BI32-1|E1BI32_BOVIN Isoform 1 of Dendrocyte expressed seven transmembrane protein OS=Bos taurus OX=9913 GN=DCSTAMP PE=4 SV=2 CANONICAL=E1BI32-1" }, "locus": { "chromosome": "14", "start_pos": 60272402, "end_pos": 60265413, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031443.5", "url": "https://www.ensembl.org/id/ENSBTAT00000031443.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000031398.3", "url": "https://www.ensembl.org/id/ENSBTAP00000031398.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512133", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512133", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LKK6-1", "protein_name": "Dendrocyte expressed seven transmembrane protein", "gene_name": "Dcstamp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLWALGTSVFLRLWGTYVFPGSTAWTNFIQHLGVCCFVALLSVSLLSAALYWVLPSAALLSAVWMATCVFLCCSKHARCFILLAIVSCGLREGRNTLLAAGTGVVIFGHVENIFSNFRGLLDSMTCNLRAKNFSTHFPLLKRYIEAIEWIYGLTTPLNVLDDLVSWNQTLAVSLFSPSHALQAHMNDTRGEVLSVLHRMVLTTELLTSVGQKLLALAGLLLILVSTGLFLKRFLGPCGWKYENVYITRQFVLFDEEERCQQRPCVLPLNRKERKKYIIVPSLKLTPKERRNLGLFFLPVLTYLYMWMLFATVDYLLYRLISSVNKQFQSLPGLEVHLRLHGEKQGTHGVIHDSAFNISMFEPSCILKPRLSVSQTWVPLSIILLTLVILGLLSSMLMQLKILVSVSFYPKVERERIEYLHAKLLEKRSKQPLGEADRKLSLYFKKIHFWLPVLKMTRKKHMIPANEDDP", "length": 470 }, "evidence": [ { "id": "E1BI32", "url": "https://omabrowser.org/oma/group/E1BI32/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S1E4-1", "protein_name": "Dendrocyte expressed seven transmembrane protein", "gene_name": "DCSTAMP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGVWTSGTDILLSVWSMYVSPRSPGWIDFTQHLGVCCLVAFISMGLLSGAFYWFLSSFIVFTASWMVTCALLCCSKHARCFILLFFLSCGLREGRNALIATGTGIVIFGHIENIFHNFKGLLDSMTCNLKAKSFSIHFPFLKKYIEAIRWMYGLATHLSLFDDLVSWNQTLAVSFFSPSQALDAQLNNTTDKALGVLYQIVTATEVVSSMGQQLLALMGLLLVLLGTGLFMKRYLDPCGWKFENIYITKQFVRFDERERHEQRPCVLPLNKQERKKYVVIPSFWLTPKDKKNLGLYFLPVLTHLCIWVLFAAIDYLLYWLIFSVSKHFQSLPGLEVHLKLHREAQGTQDIIHNSSFNISLFEPNCIPKPKLFLAKIWIPLSIILVILVMLGLLSPFLMQLKILVSASFYPSVQQERVLYLHAKMLKKRTKQPVGGVKRKQYFTKIHFWLPVLKMIGKKQMDTAREDNPWKAAGSTSAHHTSSSAQVG", "length": 487 }, "evidence": [ { "id": "E1BI32", "url": "https://omabrowser.org/oma/group/E1BI32/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7TNJ0-1", "protein_name": "Dendritic cell-specific transmembrane protein", "gene_name": "Dcstamp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLWTLGTSIFLRLWGTYVFPRSPSWLDFIQHLGVCCFVAFLSVSLFSAAFYWILPPVALLSSVWMITCVFLCCSKRARCFILLAVLSCGLREGRNALIAAGTGVVIFGHVENIFYNFRGLLDSMTCNLRAKSFSVHFPLLKRYTEAIQWIYGLATPLNLFDDLVSWNQTLVVSLFSPSHALEAHMNDTRGEVLGVLHHMVVTTELLTSVGQKLLALAGLLLILVSTGLFLKRFLGPCGWKYENVYITKQFVRFDEKERHQQRPCVLPLNKKERKKYVIVPSLQLTPKEKKTLGLFFLPVLTYLYMWVLFAAVDYLLYRLISSMNKQFQSLPGLEVHLKLRGEKQGTQGVVHDSAFNISMFEPSCIPKPRLSVSETWVPLSIILLTLIILGLLSSMLMQLKILVSVSFYPKVERERIEYLHAKLLEKRSKQPLREADGKPSLYFKKIHFWFPVLKMIRKKQTIPANEDDL", "length": 470 }, "evidence": [ { "id": "E1BI32", "url": "https://omabrowser.org/oma/group/E1BI32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H295-1", "protein_name": "Dendritic cell-specific transmembrane protein", "gene_name": "DCSTAMP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.ebi.ac.uk/interpro/entry/IPR036431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BI80", "url": "https://www.orthodb.org/?gene=E1BI80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15348:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15348:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005222023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BI80", "url": "https://www.uniprot.org/uniprotkb/E1BI80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI80-1", "url": "https://www.uniprot.org/uniprotkb/E1BI80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPLHPQQKQPPPPQPPHLAPLQMDAREKQGQQMRETPFLYAQKLVTQQTHLSATPGRPSGSPALGPSARVPPATAVARVFERSKVNSEPEEEEGGLEGEDGDDEAEVAEKQTQAASKYFHVQKVARQDPRAAPLPGLLPAPGLAPHGQQAKEDRTKDASKTSASVSAAGQPGWNRDEQLKQNGGLAWSDDADGGRGREISRDFAKLYELDSDPERKEFLDDLFVFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRRPSYSSSLFGYSPTAAAGAPALLSPPKIRFPILGLGSSGGTSASGSRISPAAPLRKGDGVPVTTVPVPNRLAVPVTLAGQQASTRTATLEQLRERLESGEPPEKKVSRLSEEEQRLVQQAFQRNLFNMARQLPMKIRINGRAEDRAEASAAALNLTTSSIGSISMSVDIDGTTYAGVLFAQKPAVHLITGSAPQSIGSSSSSSSSSHCSPSPTSSRGTPSAEPSTSWSL", "length": 554, "header": "tr|E1BI80-1|E1BI80_BOVIN Isoform 1 of AT-rich interactive domain-containing protein 3 OS=Bos taurus OX=9913 GN=ARID3B PE=4 SV=3 CANONICAL=E1BI80-1" }, "isoforms": [ { "isoform_ac": "E1BI80-1", "url": "https://www.uniprot.org/uniprotkb/E1BI80/entry#E1BI80-1", "sequence": { "sequence": "MEPLHPQQKQPPPPQPPHLAPLQMDAREKQGQQMRETPFLYAQKLVTQQTHLSATPGRPSGSPALGPSARVPPATAVARVFERSKVNSEPEEEEGGLEGEDGDDEAEVAEKQTQAASKYFHVQKVARQDPRAAPLPGLLPAPGLAPHGQQAKEDRTKDASKTSASVSAAGQPGWNRDEQLKQNGGLAWSDDADGGRGREISRDFAKLYELDSDPERKEFLDDLFVFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRRPSYSSSLFGYSPTAAAGAPALLSPPKIRFPILGLGSSGGTSASGSRISPAAPLRKGDGVPVTTVPVPNRLAVPVTLAGQQASTRTATLEQLRERLESGEPPEKKVSRLSEEEQRLVQQAFQRNLFNMARQLPMKIRINGRAEDRAEASAAALNLTTSSIGSISMSVDIDGTTYAGVLFAQKPAVHLITGSAPQSIGSSSSSSSSSHCSPSPTSSRGTPSAEPSTSWSL", "length": 554, "header": "tr|E1BI80-1|E1BI80_BOVIN Isoform 1 of AT-rich interactive domain-containing protein 3 OS=Bos taurus OX=9913 GN=ARID3B PE=4 SV=3 CANONICAL=E1BI80-1" }, "locus": { "chromosome": "21", "start_pos": 34128717, "end_pos": 34086052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015698.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015698.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015698.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015698.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 538, "start_aa": "Thr", "end_pos": 538, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr538", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 543, "start_aa": "Thr", "end_pos": 543, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr543", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BI80", "url": "https://www.uniprot.org/uniprotkb/E1BI80" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BI80", "url": "https://www.uniprot.org/uniprotkb/E1BI80" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BI80", "url": "https://www.uniprot.org/uniprotkb/E1BI80" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BI80", "url": "https://www.uniprot.org/uniprotkb/E1BI80" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BI80", "url": "https://www.uniprot.org/uniprotkb/E1BI80" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BI80", "url": "https://www.uniprot.org/uniprotkb/E1BI80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BI80-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 554, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BI80-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BI80" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI80" }, { "id": "PS51011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ARID", "eco_id": "ECO_0000259", "start_pos": 213, "end_pos": 305, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI80" }, { "id": "PS51486", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51486" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "REKLES", "eco_id": "ECO_0000259", "start_pos": 412, "end_pos": 510, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 538, 543 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 479, "end_pos": 481 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BI93-1", "uniprot_ac": "E1BI93", "uniprot_id": "E1BI93_BOVIN", "mass": { "chemical_mass": 86911.0, "monoisotopic_mass": 86911.0 }, "refseq": {}, "gene_names": [ { "name": "CBARP", "type": "recommended", "evidence": [ { "id": "E1BI93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI93" } ] } ], "protein_names": [ { "name": "CACN subunit beta associated regulatory protein", "type": "synonym", "evidence": [ { "id": "E1BI93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI93/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BI93", "url": "https://www.uniprot.org/uniprotkb/E1BI93" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CBARP", "url": "https://www.uniprot.org/uniprotkb/E1BI93", "locus": { "chromosome": "7", "start_pos": 43673071, "end_pos": 43680982, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025233", "url": "https://www.ensembl.org/id/ENSBTAG00000025233" } ] } } ], "crossref": [ { "id": "E1BI93", "url": "https://alphafold.ebi.ac.uk/entry/E1BI93", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000025233", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000025233", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "785529", "url": "https://www.ncbi.nlm.nih.gov/gene/785529", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28597", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28597", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28597:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28597:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NWJ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI93", "url": "https://www.uniprot.org/uniprotkb/E1BI93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI93-1", "url": "https://www.uniprot.org/uniprotkb/E1BI93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QPTRSRVQPLLSRLPPPRAALSIHKFSSCCYRRYRAPEPAGSAAQPPARRPWAAHPGAEPHHAAHGHHGHGRRCHHHRHGCPDHDVGQRHGSPYSRAWPNPGQLSAADGGDGALCRGRPRGAVGCASALQALLGGAPTPPQSPRGSREDHHHLPGQRCPPHPRLGAARFRLISVSLSPRVGAHRRVLHPEFRGEDPEGQDTETQRFLSTSSTGRRVSFNEAALFEQSRKAQDKGRRYTLTEGDFHHLKNARLTHLHLPPLKIVTIHECDSGEASATATPHSTVVPKASLAIFQPPGKALTGRSVGPSSALPGDPYNSAVGPANFGISPSASSDSGEGSSLDTGARSAKPGVQGAAAGPGEAGPGSGAGPVLQFFTRLRRHASLDGASPYFKVKKWKLEPSQRASSLDTRGSPKRHHFQRQRAASESMEQEEGDAPHVDFIQYIASAGDTMVFPSPRPFLASPTSPPPSLGRLEAAEEVGAAGGASPESPLERGIIAGPEQLQDSDGERDAGLEQAPTIYRDIWSLRASLELHAAASSDHSSSGNDRDSVRSGDSSGSGSGGAAPVFPPPSPPPTPMPRPADGETGGPRKLLQMDSGYASIEGRGVGDDGPPSAPEKRSSFTSAGREATVGCSFESPAPETPVRPRSPRAWPRRAPRRDYSIDEKTDALFHEFLRHDPHFDDALSATARHRARAHPHPHARKQWQQRGRQHSDPGARAAPPTPSTAQSGAPRPARAPLRRGDSVDCPPDGRAGDDPATSSIPVIEEEPGGGCPGSGLCAGTPGALLDKLAASLDDRLFPPRLAQPVAVAPALATAAPTSPDHSPV", "length": 824, "header": "tr|E1BI93-1|E1BI93_BOVIN Isoform 1 of CACN subunit beta associated regulatory protein OS=Bos taurus OX=9913 GN=CBARP PE=4 SV=5 CANONICAL=E1BI93-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NWJ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BI93/entry#A0ABI0NWJ2-1", "sequence": { "sequence": "MGTWRSDLSRWGLPRGSPSTTTLLIMQPTATMATAAAATTTATVALTTTWDNATDRPTAEPGPILDSYLLLMVVMALFVGGALAVLSGALLLCRRCWEAHRRLHRAPEEAEKTTTTYLDNGAHPTQDPEFRGEDPEGQDTETQRFLSTSSTGRRVSFNEAALFEQSRKAQDKGRRYTLTEGDFHHLKNARLTHLHLPPLKIVTIHECDSGEASATATPHSTVVPKASLAIFQPPGKALTGRSVGPSSALPGDPYNSAVGPANFGISPSASSDSGEGSSLDTGARSAKPGVQGAAAGPGEAGPGSGAGPVLQFFTRLRRHASLDGASPYFKVKKWKLEPSQRASSLDTRGSPKRHHFQRQRAASESMEQEEGDAPHVDFIQYIASAGDTMVFPSPRPFLASPTSPPPSLGRLEAAEEVGAAGGASPESPLERGIIAGPEQLQDSDGERDAGLEQAPTIYRDIWSLRASLELHAAASSDHSSSGNDRDSVRSGDSSGSGSGGAAPVFPPPSPPPTPMPRPADGETGGPRKLLQMDSGYASIEGRGVGDDGPPSAPEKRSSFTSAGREATVGCSFESPAPETPVRPRSPRAWPRRAPRRDYSIDEKTDALFHEFLRHDPHFDDALSATARHRARAHPHPHARKQWQQRGRQHSDPGARAAPPTPSTAQSGAPRPARAPLRRGDSVDCPPDGRAGDDPATSSIPVIEEEPGGGCPGSGLCAGTPGALLDKLAASLDDRLFPPRLAQPVAVAPALATAAPTSPDHSPV", "length": 763, "header": "tr|A0ABI0NWJ2-1|A0ABI0NWJ2_BOVIN Computationally mapped isoform of CACN subunit beta associated regulatory protein OS=Bos taurus OX=9913 GN=CBARP PE=4 SV=1 CANONICAL=E1BI93-1" }, "locus": { "chromosome": "7", "start_pos": 43679203, "end_pos": 43673074, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144491.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144491.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104202.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104202.1" } ] } }, { "isoform_ac": "E1BI93-1", "url": "https://www.uniprot.org/uniprotkb/E1BI93/entry#E1BI93-1", "sequence": { "sequence": "QPTRSRVQPLLSRLPPPRAALSIHKFSSCCYRRYRAPEPAGSAAQPPARRPWAAHPGAEPHHAAHGHHGHGRRCHHHRHGCPDHDVGQRHGSPYSRAWPNPGQLSAADGGDGALCRGRPRGAVGCASALQALLGGAPTPPQSPRGSREDHHHLPGQRCPPHPRLGAARFRLISVSLSPRVGAHRRVLHPEFRGEDPEGQDTETQRFLSTSSTGRRVSFNEAALFEQSRKAQDKGRRYTLTEGDFHHLKNARLTHLHLPPLKIVTIHECDSGEASATATPHSTVVPKASLAIFQPPGKALTGRSVGPSSALPGDPYNSAVGPANFGISPSASSDSGEGSSLDTGARSAKPGVQGAAAGPGEAGPGSGAGPVLQFFTRLRRHASLDGASPYFKVKKWKLEPSQRASSLDTRGSPKRHHFQRQRAASESMEQEEGDAPHVDFIQYIASAGDTMVFPSPRPFLASPTSPPPSLGRLEAAEEVGAAGGASPESPLERGIIAGPEQLQDSDGERDAGLEQAPTIYRDIWSLRASLELHAAASSDHSSSGNDRDSVRSGDSSGSGSGGAAPVFPPPSPPPTPMPRPADGETGGPRKLLQMDSGYASIEGRGVGDDGPPSAPEKRSSFTSAGREATVGCSFESPAPETPVRPRSPRAWPRRAPRRDYSIDEKTDALFHEFLRHDPHFDDALSATARHRARAHPHPHARKQWQQRGRQHSDPGARAAPPTPSTAQSGAPRPARAPLRRGDSVDCPPDGRAGDDPATSSIPVIEEEPGGGCPGSGLCAGTPGALLDKLAASLDDRLFPPRLAQPVAVAPALATAAPTSPDHSPV", "length": 824, "header": "tr|E1BI93-1|E1BI93_BOVIN Isoform 1 of CACN subunit beta associated regulatory protein OS=Bos taurus OX=9913 GN=CBARP PE=4 SV=5 CANONICAL=E1BI93-1" }, "locus": { "chromosome": "7", "start_pos": 43680967, "end_pos": 43673074, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035381.6", "url": "https://www.ensembl.org/id/ENSBTAT00000035381.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000035256.6", "url": "https://www.ensembl.org/id/ENSBTAP00000035256.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 138, "start_aa": "Thr", "end_pos": 138, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr138", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 574, "start_aa": "Thr", "end_pos": 574, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr574", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 721, "start_aa": "Thr", "end_pos": 721, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr721", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BI93", "url": "https://www.uniprot.org/uniprotkb/E1BI93" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "E1BI93", "url": "https://www.uniprot.org/uniprotkb/E1BI93" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "E1BI93", "url": "https://www.uniprot.org/uniprotkb/E1BI93" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "E1BI93", "url": "https://www.uniprot.org/uniprotkb/E1BI93" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of calcium ion-dependent exocytosis", "id": "GO:0045955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045955", "evidence": [ { "database": "UniProtKB", "id": "E1BI93", "url": "https://www.uniprot.org/uniprotkb/E1BI93" } ], "pmid": "" }, { "name": "negative regulation of calcium ion transmembrane transport", "id": "GO:1903170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903170", "evidence": [ { "database": "UniProtKB", "id": "E1BI93", "url": "https://www.uniprot.org/uniprotkb/E1BI93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BI93-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 824, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BI93-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BI93" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 138, 574, 721 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIA2-1", "uniprot_ac": "E1BIA2", "uniprot_id": "E1BIA2_BOVIN", "mass": { "chemical_mass": 25976.0, "monoisotopic_mass": 25976.0 }, "refseq": { "ac": "NP_001180054", "name": "transmembrane gamma-carboxyglutamic acid protein 4 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180054" }, "gene_names": [ { "name": "PRRG4", "type": "recommended", "evidence": [ { "id": "E1BIA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA2" } ] }, { "name": "PRRG4", "type": "synonym", "evidence": [ { "id": "NP_001180054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180054" } ] } ], "protein_names": [ { "name": "Proline rich and Gla domain 4", "type": "synonym", "evidence": [ { "id": "E1BIA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA2/entry#names_and_taxonomy" } ] }, { "name": "transmembrane gamma-carboxyglutamic acid protein 4 precursor", "type": "synonym", "evidence": [ { "id": "NP_001180054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180054" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIA2", "url": "https://www.uniprot.org/uniprotkb/E1BIA2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRRG4", "url": "https://www.uniprot.org/uniprotkb/E1BIA2", "locus": { "chromosome": "15", "start_pos": 63530238, "end_pos": 63514800, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020731", "url": "https://www.ensembl.org/id/ENSBTAG00000020731" } ] } } ], "crossref": [ { "id": "E1BIA2", "url": "https://alphafold.ebi.ac.uk/entry/E1BIA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020731", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020731", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "616767", "url": "https://www.ncbi.nlm.nih.gov/gene/616767", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616767", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616767", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WKDVFTS", "url": "https://omabrowser.org/oma/group/WKDVFTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIA2", "url": "https://www.orthodb.org/?gene=E1BIA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24278", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24278", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24278:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24278:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00594", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00594", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180054", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BIA2", "url": "https://www.uniprot.org/uniprotkb/E1BIA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIA2-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFPLLVLLSQLPVVTFAFPHCTRSPSEESRHAREEVFTSKEEANLFIHRHLLYNRFDLELFTPGDLERECIEELCNYEEAREIFVDEDKTMKFWQEYSVRGPTTKSDANREKIDVMGLLTGLIAAGVFLVILGLVGYYLCITKCHRQQYPGSSDICVRRGRHTPSIIFRRPEEAVLSPSPPSLEDTGLPSYEQAVALTRKQSVSPPPPYPGPANDFRVFKKSMSLPSH", "length": 228, "header": "tr|E1BIA2-1|E1BIA2_BOVIN Isoform 1 of Proline rich and Gla domain 4 OS=Bos taurus OX=9913 GN=PRRG4 PE=4 SV=1 CANONICAL=E1BIA2-1" }, "isoforms": [ { "isoform_ac": "E1BIA2-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA2/entry#E1BIA2-1", "sequence": { "sequence": "MFPLLVLLSQLPVVTFAFPHCTRSPSEESRHAREEVFTSKEEANLFIHRHLLYNRFDLELFTPGDLERECIEELCNYEEAREIFVDEDKTMKFWQEYSVRGPTTKSDANREKIDVMGLLTGLIAAGVFLVILGLVGYYLCITKCHRQQYPGSSDICVRRGRHTPSIIFRRPEEAVLSPSPPSLEDTGLPSYEQAVALTRKQSVSPPPPYPGPANDFRVFKKSMSLPSH", "length": 228, "header": "tr|E1BIA2-1|E1BIA2_BOVIN Isoform 1 of Proline rich and Gla domain 4 OS=Bos taurus OX=9913 GN=PRRG4 PE=4 SV=1 CANONICAL=E1BIA2-1" }, "locus": { "chromosome": "15", "start_pos": 63529682, "end_pos": 63515385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027625.8", "url": "https://www.ensembl.org/id/ENSBTAT00000027625.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027625.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027625.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616767", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616767", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SUT8-1", "protein_name": "Proline rich and Gla domain 4", "gene_name": "PRRG4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTLLVLLSQLPVITFAFPHLTSPEESRHAGEEVFISKEEANWFIRRHLLYNRFDLELFTPGDLERECREELCNYEEAREIFVDEDKTMTFWQDYSIKGPITITDGNREKIDVMGLLTGLIAAGVFLVIFGLLGYYLCITKCNRQGHPGSSATHIRRGRHTPSIIFRRPEEAVLSPSPPSVEDTGLPSYEQAVALTRKHSVSPPPPYPGPAKGFGVFKKSMSLPSH", "length": 226 }, "evidence": [ { "id": "E1BIA2", "url": "https://omabrowser.org/oma/group/E1BIA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2N1K4-1", "protein_name": "Transmembrane gamma-carboxyglutamic acid protein 4", "gene_name": "Prrg4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFPLLIVLSLLTRLTLAVPLCVKRLKDSEHAGEEVFVSKEAANIFMHRRLLYNRFDLELFTPGDLERECYEEFCNYEEAREIFRDDEKAITFWRDYSTKGPTTRSDVNKEKIDVMGLLTGLIAAGVFLVIFGLFGYYLCITKCNRQRYLGSSAVYTRRAQHTPSVIFRSPEETVLPSSPPSEDAGLPSYEQAVAMTRKHSVSPPPPYPGSTIGFRVFKKSMSLPSH", "length": 226 }, "evidence": [ { "id": "E1BIA2", "url": "https://omabrowser.org/oma/group/E1BIA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V1A1Q8-1", "protein_name": "Proline rich and Gla domain 4", "gene_name": "PRRG4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSCVGLIQASSVGRLRCHCVEVLVSVGQVRAMLGLLLLCQLQVTVSAFLHRAQRPSGSEQPDAAYVFASAKEANLFIGRHLLNNRFDFEAFTPDNLERECMEELCSYEEAREIFEDPDRTTQFWSGYSATGPRIKTGDETLQQINITGLLIGPIAAGGMLAIIGLLIFYCCKDRCKSRQPPGHLDHGRSRRHSSTSIFRRHEELSLNPLPPRTDDSGLPTYEQAVTSGSQHDAPPPPYPGPPKWVRAFRKSMSLPAP", "length": 258 }, "evidence": [ { "id": "E1BIA2", "url": "https://omabrowser.org/oma/group/E1BIA2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8BGN6-1", "protein_name": "Transmembrane gamma-carboxyglutamic acid protein 4", "gene_name": "Prrg4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFPLLIVLSQLPRLTLAVPHCIRSLKDSEHAPEEVFASKEAANIFMHRRLLNNRFDLELFTPGDLERECYEEFCSYEEAREILGDDENTIKFWQTYSIKGPTTGSDVNKEKIDVMSLLTGLIVAGVFLVIFGLVGYYVCLTKCKRRPYPSSSANYTRTARYTPSIVFRSPEEAVLSPSTSSEDAGLPSYEQAVALTRKHSVSPPPPYPGPARGFRVFKKSMSLPSH", "length": 226 }, "evidence": [ { "id": "E1BIA2", "url": "https://omabrowser.org/oma/group/E1BIA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZD6-1", "protein_name": "Transmembrane gamma-carboxyglutamic acid protein 4", "gene_name": "PRRG4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFTLLVLLSQLPTVTLGFPHCARGPKASKHAGEEVFTSKEEANFFIHRRLLYNRFDLELFTPGNLERECNEELCNYEEAREIFVDEDKTIAFWQEYSAKGPTTKSDGNREKIDVMGLLTGLIAAGVFLVIFGLLGYYLCITKCNRLQHPCSSAVYERGRHTPSIIFRRPEEAALSPLPPSVEDAGLPSYEQAVALTRKHSVSPPPPYPGHTKGFRVFKKSMSLPSH", "length": 226 }, "evidence": [ { "id": "E1BIA2", "url": "https://omabrowser.org/oma/group/E1BIA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "E1BIA2", "url": "https://www.uniprot.org/uniprotkb/E1BIA2" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BIA2", "url": "https://www.uniprot.org/uniprotkb/E1BIA2" } ], "pmid": "" }, { "name": "WW 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"https://www.uniprot.org/uniprotkb/E1BIA2" } ], "pmid": "" }, { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "E1BIA2", "url": "https://www.uniprot.org/uniprotkb/E1BIA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIA2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 228, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIA2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIA2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA2" }, { "id": "PS50998", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50998" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gla", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 99, "start_aa": "Tyr", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIA3-1", "uniprot_ac": "E1BIA3", "uniprot_id": "E1BIA3_BOVIN", "mass": { "chemical_mass": 46921.0, "monoisotopic_mass": 46921.0 }, "refseq": { "ac": "NP_001192819", "name": "potassium channel subfamily K member 12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192819" }, "gene_names": [ { "name": "KCNK12", "type": "recommended", "evidence": [ { "id": "E1BIA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA3" } ] }, { "name": "KCNK12", "type": "synonym", "evidence": [ { "id": "NP_001192819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192819" } ] } ], "protein_names": [ { "name": "Potassium two pore domain channel subfamily K member 12", "type": "synonym", "evidence": [ { "id": "E1BIA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA3/entry#names_and_taxonomy" } ] }, { "name": "potassium channel subfamily K member 12", "type": "synonym", "evidence": [ { "id": "NP_001192819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192819" } ] }, { "name": "potassium channel, subfamily K, member 12", "type": "synonym", "evidence": [ { "id": "NP_001192819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192819" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIA3", "url": "https://www.uniprot.org/uniprotkb/E1BIA3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KCNK12", "url": "https://www.uniprot.org/uniprotkb/E1BIA3", "locus": { "chromosome": "11", "start_pos": 29914745, "end_pos": 29963621, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017500", "url": "https://www.ensembl.org/id/ENSBTAG00000017500" } ] } } ], "crossref": [ { "id": "E1BIA3", "url": "https://alphafold.ebi.ac.uk/entry/E1BIA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017500", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017500", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "521931", "url": "https://www.ncbi.nlm.nih.gov/gene/521931", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521931", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521931", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MRACHER", "url": "https://omabrowser.org/oma/group/MRACHER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIA3", "url": "https://www.orthodb.org/?gene=E1BIA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192819", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192819", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BIA3", "url": "https://www.uniprot.org/uniprotkb/E1BIA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIA3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSRSPRPPPRRCRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADCLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRLAETSASR", "length": 430, "header": "tr|E1BIA3-1|E1BIA3_BOVIN Isoform 1 of Potassium two pore domain channel subfamily K member 12 OS=Bos taurus OX=9913 GN=KCNK12 PE=3 SV=1 CANONICAL=E1BIA3-1" }, "isoforms": [ { "isoform_ac": "E1BIA3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA3/entry#E1BIA3-1", "sequence": { "sequence": "MSSRSPRPPPRRCRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADCLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRLAETSASR", "length": 430, "header": "tr|E1BIA3-1|E1BIA3_BOVIN Isoform 1 of Potassium two pore domain channel subfamily K member 12 OS=Bos taurus OX=9913 GN=KCNK12 PE=3 SV=1 CANONICAL=E1BIA3-1" }, "locus": { "chromosome": "11", "start_pos": 29963599, "end_pos": 29915111, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023260.3", "url": "https://www.ensembl.org/id/ENSBTAT00000023260.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023260.2", "url": "https://www.ensembl.org/id/ENSBTAP00000023260.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 336, "start_aa": "Thr", "end_pos": 336, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr336", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:521931", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521931", "resource": "KEGG Pathway" }, { "id": "R-BTA-5576886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576886", "resource": "Reactome", "description": "Phase 4 - resting membrane potential" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NV35-1", "protein_name": "Potassium two pore domain channel subfamily K member 12", "gene_name": "KCNK12", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMPRRGAAGPRRRRRPAPLNEDNGRFLLLAALIAAYLSAGATVFSALESPSEAAAQLRWNRTLHNFSRIFNISLPELRAFLRSYEAAMAAGIRVDALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVAGKVFLIVYGLFGCAGTILFFNLFLERIISLLAFIMKACHERQLRRSGLLPPNFRRGSAMSGVGSLIGWKPSVYHVMLILGIFAITLSCCASAMYTLVEGWNYVDSLYYCFVTFSTIGFGDLVSSQNAVYQNQGLYRFGNFIFILMGVCCIYSLFNVISIVIKQLLNWVLKKFRCRCCPKCHKSSTRLGRRNAITPGARLRRHKISLEADGQYDSDTDGRRLSGEMISMRELTASNKVSLAILQKQLYETANGYPRNVCINTRQNGFSAGVGALAIMNNRLAETSDSR", "length": 415 }, "evidence": [ { "id": "E1BIA3", "url": "https://omabrowser.org/oma/group/E1BIA3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SQH8-1", "protein_name": "Potassium two pore domain channel subfamily K member 12", "gene_name": "KCNK12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSRSPRPPPRRCRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACREHQLRRSGLLPATFRRGSALSEADCLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRLAETSASR", "length": 430 }, "evidence": [ { "id": "E1BIA3", "url": "https://omabrowser.org/oma/group/E1BIA3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9HB15-1", "protein_name": "Potassium channel subfamily K member 12", "gene_name": "KCNK12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSRSPRPPPRRSRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRLAETSASR", "length": 430 }, "evidence": [ { "id": "E1BIA3", "url": "https://omabrowser.org/oma/group/E1BIA3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "E1BIA3", "url": "https://www.uniprot.org/uniprotkb/E1BIA3" } ], "pmid": "" }, { "name": "potassium ion leak channel activity", "id": "GO:0022841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022841", "evidence": [ { "database": "UniProtKB", "id": "E1BIA3", "url": "https://www.uniprot.org/uniprotkb/E1BIA3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BIA3", "url": "https://www.uniprot.org/uniprotkb/E1BIA3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BIA3", "url": "https://www.uniprot.org/uniprotkb/E1BIA3" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "E1BIA3", "url": "https://www.uniprot.org/uniprotkb/E1BIA3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BIA3", "url": "https://www.uniprot.org/uniprotkb/E1BIA3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BIA3", "url": "https://www.uniprot.org/uniprotkb/E1BIA3" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "E1BIA3", "url": "https://www.uniprot.org/uniprotkb/E1BIA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "E1BIA3", "url": "https://www.uniprot.org/uniprotkb/E1BIA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35526-1" ], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIA3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 430, "overlap": "1.0", "method": "AlphaFold", "type": 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"PTHR24027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027:SF290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027:SF290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-418990", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418990", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001069734", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069734", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BIA5", "url": 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"MTIYQFLLLFLLWVCLPRFCSPEIMFRRTPVPQKRILGARVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIITEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSTSSPVRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKEMTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDNQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNADVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTDGDQNYDYLREWGPRFNKLAEMYGGGESDKDA", "length": 788, "header": "tr|E1BIA5-1|E1BIA5_BOVIN Isoform 1 of Cadherin-10 OS=Bos taurus OX=9913 GN=CDH10 PE=4 SV=2 CANONICAL=E1BIA5-1" }, "isoforms": [ { "isoform_ac": "E1BIA5-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA5/entry#E1BIA5-1", "sequence": { "sequence": "MTIYQFLLLFLLWVCLPRFCSPEIMFRRTPVPQKRILGARVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIITEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSTSSPVRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKEMTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDNQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNADVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTDGDQNYDYLREWGPRFNKLAEMYGGGESDKDA", "length": 788, "header": "tr|E1BIA5-1|E1BIA5_BOVIN Isoform 1 of Cadherin-10 OS=Bos taurus OX=9913 GN=CDH10 PE=4 SV=2 CANONICAL=E1BIA5-1" }, "locus": { "chromosome": "20", "start_pos": 48997853, "end_pos": 48881251, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003688.8", "url": "https://www.ensembl.org/id/ENSBTAT00000003688.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003688.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003688.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:541259", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541259", "resource": "KEGG Pathway" }, { "id": "R-BTA-418990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418990", "resource": "Reactome", "description": "Adherens junctions interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GQU6-1", "protein_name": "Cadherin-10", "gene_name": "LOC100768913", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTFYQFLRLFVLWACLPHFCSPELTFRRTPELQQMIAEARVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAVGSVKATDADMGKNAEVDYRIIDGDGTDMFDIITEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSASSPIRFTLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVSVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKTEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTVPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESDKDA", "length": 788 }, "evidence": [ { "id": "E1BIA5", "url": "https://omabrowser.org/oma/group/E1BIA5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1LR98-1", "protein_name": "Cadherin-10", "gene_name": "Cdh10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIYSFLRLFVLWACLPQFCCPELTFRRTPGLQQMTAESHVPRGDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENKEQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAVGSVKATDADTGKNAEVDYRIIDGDGTDMFDIITEKDTQEGIITVKKPLDYENRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSTSSPIRFTLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVSVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSVAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESDKDA", "length": 786 }, "evidence": [ { "id": "E1BIA5", "url": "https://omabrowser.org/oma/group/E1BIA5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SRL4-1", "protein_name": "Cadherin-10", "gene_name": "CDH10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTIYQFLLLFLLWVCLPHFCSPEIMFKRTPVPQKRVLGARTPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIITEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSTSSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKEMTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTDGDQNYDYLREWGPRFNKLAEMYGGGESDKDS", "length": 788 }, "evidence": [ { "id": "E1BIA5", "url": "https://omabrowser.org/oma/group/E1BIA5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P70408-1", "protein_name": "Cadherin-10", "gene_name": "Cdh10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTIYQFLRLFVLWACLPHFCCPELTFRRTPGIQQMTAESRAPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENKEQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAVGSVKATDADTGKNAEVDYRIIDGDGTDMFDIITEKDTQEGIITVKKPLDYENRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSTSSPIRFTLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVSVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSVAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESDKDA", "length": 788 }, "evidence": [ { "id": "E1BIA5", "url": "https://omabrowser.org/oma/group/E1BIA5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P79995-1", "protein_name": "Cadherin-10", "gene_name": "CDH10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTIQQVLLLLLLWMWLLHPCRTEMLFRRTPDLRPKGFVGRTSGSDGKALHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARIIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTIHLRIPESSPVGTPIGSIKATDADTGKNAEVEYRIIDGDGTDMFDIVTQRDTQEGIITVRKPLDYETRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISVEDVDEPPVFSRSSYLFEVHEDIELGTIIGTVMARDPDSASSPIRFSLDRHTDLDRIFNIHSGNGSIYTSKPLDREISQWHNLSVIAAEINNLKDTTRVPVYVRILDVNDNAPQFAVFYDTFVCENARAGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRRNGFSRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSRGNMQSCNAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEDKKLRRDIIPETLFVPRRTPSAPDNTDVRDFINQRLKEHDSDPSAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESDKDAS", "length": 789 }, "evidence": [ { "id": "E1BIA5", "url": "https://omabrowser.org/oma/group/E1BIA5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9Y6N8-1", "protein_name": "Cadherin-10", "gene_name": "CDH10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTIHQFLLLFLFWVCLPHFCSPEIMFRRTPVPQQRILSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESDKDS", "length": 788 }, "evidence": [ { "id": "E1BIA5", "url": "https://omabrowser.org/oma/group/E1BIA5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" }, { "name": "cell-cell junction assembly", "id": "GO:0007043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007043", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" }, { "name": "adherens junction organization", "id": "GO:0034332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034332", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" }, { "name": "synaptic membrane adhesion", "id": "GO:0099560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099560", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "E1BIA5", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 741, "end_pos": 743, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIA5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 788, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIA5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIA5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA5" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 160, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 438, "end_pos": 440 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 741, "end_pos": 743 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIA9-1", "uniprot_ac": "E1BIA9", "uniprot_id": "E1BIA9_BOVIN", "mass": { "chemical_mass": 103879.0, "monoisotopic_mass": 103879.0 }, "refseq": { "ac": "XP_003586802", "name": "transcription initiation factor TFIID subunit 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586802" }, "gene_names": [ { "name": "TAF3", "type": "recommended", "evidence": [ { "id": "E1BIA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA9" } ] }, { "name": "TAF3", "type": "synonym", "evidence": [ { "id": "XP_003586802", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586802" } ] } ], "protein_names": [ { "name": "Transcription initiation factor TFIID subunit 3", "type": "recommended", "evidence": [ { "id": "E1BIA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA9/entry#names_and_taxonomy" } ] }, { "name": "140 kDa TATA box-binding protein-associated factor", "type": "synonym", "evidence": [ { "id": "E1BIA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA9/entry#names_and_taxonomy" } ] }, { "name": "TBP-associated factor 3", "type": "synonym", "evidence": [ { "id": "E1BIA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA9/entry#names_and_taxonomy" } ] }, { "name": "Transcription initiation factor TFIID 140 kDa subunit", "type": "synonym", "evidence": [ { "id": "E1BIA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIA9/entry#names_and_taxonomy" } ] }, { "name": "transcription initiation factor TFIID subunit 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003586802", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586802" } ] } ], "function": [ { "annotation": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF3 forms the TFIID-A module together with TAF5 and TBP. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The TAF3-TBPL2 complex replaces TFIID at specific promoters at an early stage in the differentiation process.", "evidence": [ { "database": "UniProtKB", "id": "E1BIA9", "url": "https://www.uniprot.org/uniprotkb/E1BIA9#function" }, { "database": "UniProtKB", "id": "ARBA00057922", "url": "https://www.uniprot.org/uniprotkb/ARBA00057922#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIA9", "url": "https://www.uniprot.org/uniprotkb/E1BIA9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TAF3", "url": "https://www.uniprot.org/uniprotkb/E1BIA9", "locus": { "chromosome": "13", "start_pos": 15964897, "end_pos": 16086369, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002836", "url": "https://www.ensembl.org/id/ENSBTAG00000002836" } ] } } ], "crossref": [ { "id": "E1BIA9", "url": "https://alphafold.ebi.ac.uk/entry/E1BIA9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002836", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002836", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15522", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15522", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22916", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22916", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506674", "url": "https://www.ncbi.nlm.nih.gov/gene/506674", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:506674", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506674", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ENIHMRQ", "url": "https://omabrowser.org/oma/group/ENIHMRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIA9", "url": "https://www.orthodb.org/?gene=E1BIA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46452:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46452:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07524", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6804756", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73776", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73776", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73779", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73779", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-75953", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75953", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-76042", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003586802", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586802", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BIA9", "url": "https://www.uniprot.org/uniprotkb/E1BIA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVSLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYMPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEEMPAMKRPRLLSTKGDALDVVLLEAREPLSSLNPQKIPPMLSPVHTQDSTDPAPPSPEPPMLAPVAKSQMPTTKPLEAKSFTPKTKTKTSSPGQKTKSPKMIPSPAMVGSPIRSPKTISKEKKSPGRSKSPKSPKSPKVMTHIPQVPVRPDTPNRTPSATISEKISKETVQVKQIQTLPDAGRLNSESQLRKAVVTDKTIDDSIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGSDSATPKASTSSNNFPKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKMGTPPSMPPSFPYISSPSVSPPTPEPAHKVYEEKPKPPASLDVKKKLKKELKTKMKKKEKQRDKERDRDKSKEKSKEKEKGKEKEKDREATKEAKYPWKDFLKDEEADPYKFKIKEFEDVDPKARLKDGIVRKEKEKHKDKKKDREKGKKDKEKRDKEKVKEKGREEKLKAPPAPLVLPPKDVALPLFSPAAAMRITAVLPSLTPVLPEKLFEEKEKPKEKERKKDKKEKKKKKEKEKEKEKKEKEREKEKREREKREKEKERHKHEKIKVEPVVPAPSPVIPRLTLKVGAGQDKIVISKVVPAPEAKPAPSLNRPKTPPPAPAPAPAAMHVTPAPVPLPLLAPASAPLAGMPAPAPAASGAASSKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMAAPPEEMQWFCPKCCNRKKDKKHKKRKHRAH", "length": 932, "header": "tr|E1BIA9-1|E1BIA9_BOVIN Isoform 1 of Transcription initiation factor TFIID subunit 3 OS=Bos taurus OX=9913 GN=TAF3 PE=3 SV=1 CANONICAL=E1BIA9-1" }, "isoforms": [ { "isoform_ac": "E1BIA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BIA9/entry#E1BIA9-1", "sequence": { "sequence": "MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVSLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYMPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEEMPAMKRPRLLSTKGDALDVVLLEAREPLSSLNPQKIPPMLSPVHTQDSTDPAPPSPEPPMLAPVAKSQMPTTKPLEAKSFTPKTKTKTSSPGQKTKSPKMIPSPAMVGSPIRSPKTISKEKKSPGRSKSPKSPKSPKVMTHIPQVPVRPDTPNRTPSATISEKISKETVQVKQIQTLPDAGRLNSESQLRKAVVTDKTIDDSIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGSDSATPKASTSSNNFPKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKMGTPPSMPPSFPYISSPSVSPPTPEPAHKVYEEKPKPPASLDVKKKLKKELKTKMKKKEKQRDKERDRDKSKEKSKEKEKGKEKEKDREATKEAKYPWKDFLKDEEADPYKFKIKEFEDVDPKARLKDGIVRKEKEKHKDKKKDREKGKKDKEKRDKEKVKEKGREEKLKAPPAPLVLPPKDVALPLFSPAAAMRITAVLPSLTPVLPEKLFEEKEKPKEKERKKDKKEKKKKKEKEKEKEKKEKEREKEKREREKREKEKERHKHEKIKVEPVVPAPSPVIPRLTLKVGAGQDKIVISKVVPAPEAKPAPSLNRPKTPPPAPAPAPAAMHVTPAPVPLPLLAPASAPLAGMPAPAPAASGAASSKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMAAPPEEMQWFCPKCCNRKKDKKHKKRKHRAH", "length": 932, "header": "tr|E1BIA9-1|E1BIA9_BOVIN Isoform 1 of Transcription initiation factor TFIID subunit 3 OS=Bos taurus OX=9913 GN=TAF3 PE=3 SV=1 CANONICAL=E1BIA9-1" }, "locus": { "chromosome": "13", "start_pos": 16086169, "end_pos": 15965901, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003674.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003674.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003674.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003674.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 501, "start_aa": "Thr", "end_pos": 501, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr501", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 811, "start_aa": "Thr", "end_pos": 811, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr811", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:506674", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506674", "resource": "KEGG Pathway" }, { "id": "R-BTA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-BTA-6804756", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "resource": "Reactome", "description": "Regulation of TP53 Activity through Phosphorylation" }, { "id": "R-BTA-73776", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73776", "resource": "Reactome", "description": "RNA Polymerase II Promoter Escape" }, { "id": "R-BTA-73779", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73779", "resource": "Reactome", "description": "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" }, { "id": "R-BTA-75953", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75953", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation" }, { "id": "R-BTA-76042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76042", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation And Promoter Clearance" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NZW0-1", "protein_name": "Transcription initiation factor TFIID subunit 3", "gene_name": "TAF3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCETYSRWLLRVSVAQICQALGWDSVQVSACDLLTDVLQRYLQGLGRGCHRYCELYGRTDPILDDVGDAFKLMGVNLHELEDYIHNIEPVTFAHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYMPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEEGDMEEDEAINDENYLSKRPLESPDAEEFPPMKRPKLSVSKGDALDGALEPREPLSSINTQKVPPMLSPVHVQDSTDLAPPSPEPPMLAPIAKSQVPTPKTLESKPPAPKTKSKTSSPGQKTKSPKTTPSPVVAGSPIRSPKTGSKEKKSPGRAKSPKSPKSPKAPVHVPPPPVKPETPSRTPLAALSDKIGKENIQVKQGQTPPEPVTKPNIENQTKKLPVMDKTIDDSIDAVIARACAEREPDPFEFSSGSESEGEIFTSPKRLSVSETTATTPKPSVSTNCSNKAGATPVPPSGGTSSSDISWTMDDSIDEVIRKANMGTPSNPPANFTYFSSPSASPPTPEPLLKVYEEKTKLASSVEVKKKLKKELKTKMKKKEKQKEKDKEKSKEKNKEKEKNKEKDKDKEGNKEAKFQWKELLKDDEHDPYKFKLKDFEDADTKVKLKDGNTKKEKEKHKDKKKEKEKGKKDKDKKDKEKVKDKSKEDKIKPPSAPLVLPPKEMSLPLFSTPTAMRLPSMLPSLSPMLPEKLFEDKEKPKEKKKDKKEKKKKKEREKDKEKEKKDKEKERKEREKKEKEKEKHKHEKIKVEPVVPAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPATPVSRPKTPPPVPSPVPAPVHVTPPPAPVPAPPQPTVSPALLPPASPAVSAAGGSKAPVRSVVTETVSTYVIRDEWGNQIWFCPGCNKPDDGSPMIGCDDCDDWYHWPCVGITAAPPEEMQWFCSKCANKKKDKKHKKRKHRAH", "length": 930 }, "evidence": [ { "id": "E1BIA9", "url": "https://omabrowser.org/oma/group/E1BIA9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GR60-1", "protein_name": "Transcription initiation factor TFIID subunit 3", "gene_name": "Taf3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVSEAFQLMGVNLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKDYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDEMEEEEVINDENFLGKRPLDSPEVEEMPTMKRPRLLSTKGDSLDVVLLEAREPLSSINPQKIPPMLSPVHVQDNTDLAPPSPEPPMLAPFAKSQLPTAKPLETKSFTPKTKTKASSPGQKTKSPKTTLSPARLGSPIRSPKTIPKEKKSPGRSKSPKSPKSPKIITHTPQPPARPETPNRTPSAIVVEKTVKESIPVKPTQTPPEIGKLNMEMQPKKAVVTDKTIDDSIDAVIARACAEREPDPFEFSSGSESEVDTFTSPKRISGSECTTPKASTSSNNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPSNMPPTFQYISSPSISPPTPEPLHKGYEEKAKLPSSVDVKKKLKKELKTKLKKKEKQRDREREKERNKERSKEKDKMREREKEKESAKEVRYPWKEFMKDEDPDPYKFKIREFEDIDPKVRLKDGIVRKEKEKHKDKKKDRERSKRDKDKREREKIKEKSREDKIKAPPTQLVLPPKEMALPLFSPSAAVRVPSMLPALSPMLPEKLFEEKEKPKEKERKKDKKEKKKKKEKEKEKEKKEREREKEKREREKREKEKEKHKHEKIKVEPVIPAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSLNRPKTPPPAPVPVPVRVSPTPLPPPLLAQAAMCPALMPSPAPALSGAGSAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDGCDDWYHWPCVGLMAAPPEEMQWFCAKCAKIKKDKKHKKRKHRAH", "length": 930 }, "evidence": [ { "id": "E1BIA9", "url": "https://omabrowser.org/oma/group/E1BIA9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5HZG4-1", "protein_name": "Transcription initiation factor TFIID subunit 3", "gene_name": "Taf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVNLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKDYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDEMEEEEVINDENFLGKRPLDSPEVEEMPSMKRPRLLSTKGDSLDVVLLEAREPLSSINPQKTPPVLSPVRVQDRADLAPPSPQPPMLAPFAKSQLPIAKPLETKSFTPKTKTKASSPGQKTKSPKAALSPARLGSPIRSPKTIPKEKKSPGRSKSPKSPKSPKIVAHVPQTPVRPETPNRTPSAMVVEKTVKETIPVMKPTQTPPEVVKLNIEMQPKKPVVTDKTIDDSIDAVIARACAEREPDPFEFSSGSESEGDTFTSPKRISGSECATPKASTSSNNFTKSLATPLPLSSGTSSSDNSWTMDASIDEVVRKAKLGAPSNMPPTFPYISSPSISPPTPEPLHKGYEEKAKLPSSVDVKKKLKKELKTKLKKKEKQRDRERERERNKERSKEKDKMREREKEKEAGKELKYPWRELMKDEDSDPYKFKIKEFEDIDAAKVRLKDGIVRREREKHKDKKKDRERSKREKDKRERERLKEKNREDKIKAPPTQLVLPPKEMALPLFSPSAVRVPAMLPAFSPMLPEKLFEEKEKPKEKERKKDKKEKKKKKEKEKEKEKKEREREKERREREKREKEKEKHKHEKIKVEPVIPAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSLNRPKTPPPAPVPIPVRVSPTPLQPPLLTQAAVCPALMPSPAPALSGIGSAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMAAPPEEMQWFCPKCANKIKKDKKHKKRKHRAH", "length": 932 }, "evidence": [ { "id": "E1BIA9", "url": "https://omabrowser.org/oma/group/E1BIA9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RH27-1", "protein_name": "Transcription initiation factor TFIID subunit 3", "gene_name": "taf3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCESFARSLLRVSVAQMCQAVGWDAVQLSACDLLSDVLERYVQQLAKSCHRYSELYGRTDPGLSDVDQAFGFLGVSIAELEDYVNNVEPIGYPQTIPQFPISKSSVLQFPAAGFDTDARDALRGERRDYIPEYFPPLVSLQEDEEEEEPVPADMGTSAEAMQVSMGEEEDGEEEENDENWLSRHDGQSPRPEGLLPAAKRPRLSTKPGVSPEWSYEPREPLSSLNSQHMPHSPSPPLSPELPRPPVAPPTPGHKPKLPSPSPARQKNKSPKRGGAAPTGVLGRPLTLTPPKTNQKAGKRSPGMPKSPRSPRPSSAPLGIAGRGWPGPLADDSSRDGQFKCNDTDDKDIENSIAAVIARACAGEDGTSDPFAYDSDSDSEGPHPPKPVPKHTLSHIKPPQALTSKHLLPPVPPLLNPPIRWTMDDSIDEVIRKASQGQKPIQPPSLSPLEPPYLSSPSDSPPTPPPPLKLTQERKDSPTGNLLKKKLKKDIKTKLKKKDKERLKEKGKEKGKNKEKNKEKKREKERGQVEENKMPWPELSLVVGGEERRDGIGGKKEKDKHKDKKKDKEKGKKEKEKRDKGKERGKEEKRISQGTKDIAIAVAGATSPLFSPQTCLRIPSMLPPLPPILPDKLFPHPKDIKSKDKDKKKDKKEKKKKKEKEKDREKEREKEREKERTKEKERDKEEKKKDKEKKEKTKEKEKDKPKLEKTSLMAEIPPAVPPSPVIPRLTLRVGAGQDKIVISKVVPDTEPTPPPPRTPVARMGPGARIRPPPVLPPPAPPPATPPPRPPPVLPPPPPPAAPIQTPPNQAKARGCSVVTETVSAYVIRDEWGNQIWICPGCNKADDGSPMIGCDECDDWYHWPCVGLLAAPPEDQSWFCIKCAGKKKDKKTKKRKRKAH", "length": 898 }, "evidence": [ { "id": "E1BIA9", "url": "https://omabrowser.org/oma/group/E1BIA9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5VWG9-1", "protein_name": "Transcription initiation factor TFIID subunit 3", "gene_name": "TAF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVSLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEELPAMKRPRLLSTKGDTLDVVLLEAREPLSSINTQKIPPMLSPVHVQDSTDLAPPSPEPPMLAPVAKSQMPTAKPLETKSFTPKTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPKTVSKEKKSPGRSKSPKSPKSPKVTTHIPQTPVRPETPNRTPSATLSEKISKETIQVKQIQTPPDAGKLNSENQPKKAVVADKTIEASIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGPECTTPKASTSANNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPSNMPPNFPYISSPSVSPPTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEPVALAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSQNRPKTPPPAPAPAPGPMLVSPAPVPLPLLAQAAAGPALLPSPGPAASGASAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMTAPPEEMQWFCPKCANKKKDKKHKKRKHRAH", "length": 929 }, "evidence": [ { "id": "E1BIA9", "url": "https://omabrowser.org/oma/group/E1BIA9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "E1BIA9", "url": "https://www.uniprot.org/uniprotkb/E1BIA9" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BIA9", "url": "https://www.uniprot.org/uniprotkb/E1BIA9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BIA9", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIG5-1", "uniprot_ac": "E1BIG5", "uniprot_id": "E1BIG5_BOVIN", "mass": { "chemical_mass": 39014.0, "monoisotopic_mass": 39014.0 }, "refseq": { "ac": "NP_001180074", "name": "dead end protein homolog 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180074" }, "gene_names": [ { "name": "DND1", "type": "recommended", "evidence": [ { "id": "E1BIG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIG5" } ] }, { "name": "DND1", "type": "synonym", "evidence": [ { "id": "NP_001180074", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180074" } ] } ], "protein_names": [ { "name": "Dead end protein homolog 1", "type": "recommended", "evidence": [ { "id": "E1BIG5", "database": "UniProtKB", "url": 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"reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DND1", "url": "https://www.uniprot.org/uniprotkb/E1BIG5", "locus": { "chromosome": "7", "start_pos": 51799737, "end_pos": 51803654, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018845", "url": "https://www.ensembl.org/id/ENSBTAG00000018845" } ] } } ], "crossref": [ { "id": "E1BIG5", "url": "https://alphafold.ebi.ac.uk/entry/E1BIG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018845", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018845", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12487", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12487", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20313", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20313", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "525516", "url": "https://www.ncbi.nlm.nih.gov/gene/525516", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:525516", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525516", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CERVNPV", "url": "https://omabrowser.org/oma/group/CERVNPV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIG5", "url": "https://www.orthodb.org/?gene=E1BIG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14709", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14709", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180074", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180074", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BIG5", "url": "https://www.uniprot.org/uniprotkb/E1BIG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIG5-1", "url": "https://www.uniprot.org/uniprotkb/E1BIG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSKRECELWCERVNPENKAALEAWVRETGIRLVQVNGQRKYGGPPPGWVGSPPPAGSEVFIGRLPQDVYEHQLIPLFQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATLHNHLLRPSCPLLVCRSTEKCELSVDGLPPGLSHRALLRALQPLGPGLQEALLLPSPGPTPAQIALLKFSSHRAAAMAKKALVEGQSHLCGEQVAVEWLKPDLKQRLRQQLMGTSLQCLQPEGNRLALARDQGLEFQGSQVALQLLCQRMKLGSPVFLTKCLGTSPAGWHRFWYQVVIPGHPVPFSGLIWVVLTPDGQDGHEVAKDAVSARLLEAMSESRASLLWSTGAEAGGTMVQQ", "length": 355, "header": "tr|E1BIG5-1|E1BIG5_BOVIN Isoform 1 of Dead end protein homolog 1 OS=Bos taurus OX=9913 GN=DND1 PE=4 SV=1 CANONICAL=E1BIG5-1" }, "isoforms": [ { "isoform_ac": "E1BIG5-1", "url": "https://www.uniprot.org/uniprotkb/E1BIG5/entry#E1BIG5-1", "sequence": { "sequence": "MQSKRECELWCERVNPENKAALEAWVRETGIRLVQVNGQRKYGGPPPGWVGSPPPAGSEVFIGRLPQDVYEHQLIPLFQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATLHNHLLRPSCPLLVCRSTEKCELSVDGLPPGLSHRALLRALQPLGPGLQEALLLPSPGPTPAQIALLKFSSHRAAAMAKKALVEGQSHLCGEQVAVEWLKPDLKQRLRQQLMGTSLQCLQPEGNRLALARDQGLEFQGSQVALQLLCQRMKLGSPVFLTKCLGTSPAGWHRFWYQVVIPGHPVPFSGLIWVVLTPDGQDGHEVAKDAVSARLLEAMSESRASLLWSTGAEAGGTMVQQ", "length": 355, "header": "tr|E1BIG5-1|E1BIG5_BOVIN Isoform 1 of Dead end protein homolog 1 OS=Bos taurus OX=9913 GN=DND1 PE=4 SV=1 CANONICAL=E1BIG5-1" }, "locus": { "chromosome": "7", "start_pos": 51803455, "end_pos": 51800741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025092.6", "url": "https://www.ensembl.org/id/ENSBTAT00000025092.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025092.4", "url": "https://www.ensembl.org/id/ENSBTAP00000025092.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:525516", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525516", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQ06-1", "protein_name": "Dead end protein homolog 1", "gene_name": "Dnd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MQSKRECELWCERVNPENKAALEAWVRETGIRLVQVNGQRKYGGPPPGWVGSPPPAGSEVFIGRLPQDVYEHQLIPLFQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATLHNHPLRPSCPLLVCRSTEKCELSVDGLPPGLSRRALLLALQPLGPGLQEALLLPSPGPAPAQIALLKFSSHRAAAMAKKALVEGQSHLCGEQVAVEWLKPDLKQRLRQQLMGPSLRCLQSEGSQLALARDKLESQGARAALQLLCQRMKLGTPVFLTKCLGTGPATWHHFWYQVVIPGHPVPFSGLIWVVLASDGQDGHEVAKEAVSARLLETLSESGASLLRSAVAEAGTMVQQ", "length": 353 }, "evidence": [ { "id": "E1BIG5", "url": "https://omabrowser.org/oma/group/E1BIG5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I594-1", "protein_name": "Dead end protein homolog 1", "gene_name": "Dnd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQSKRECEQWCERVNPENKAALEAWVRETGIRLVQVNGQRKYGGPPPGWVGSPPPSGSEVFIGRLPQDVYEHQLIPLFQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATLHNHQLRPSCQLLVCRSTEKCELTVDGLPPSLNRHMLLLALQPLGPCLQETLLLPSPGSAPSQIALLKFSTHRAAAMAKKALVEGQSRLCGEQVAVEWLKPDLKQHFRQQLAGPSLRFLRPEGSQVAQSRDRLGSQGARAALQLLCQRMKLGSPMFLTKCLGTGPAGWHRFWYQVVIPGHPVPFSGLIWVVLASDWQDGHEVAKDAVSAQLLEILSESRTSLWSPRAEAGTIVKQ", "length": 352 }, "evidence": [ { "id": "E1BIG5", "url": "https://omabrowser.org/oma/group/E1BIG5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6VY05-1", "protein_name": "Dead end protein homolog 1", "gene_name": "Dnd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQSKRECEQWCERVNPENKAALEAWVRETGIRLVQVNGQRKYGGPPPGWVGSPPPSGSEVYIGRLPQDVYEHQLIPLFQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATLHNHQLRPSCQLLVCRSTEKCELTVDGLPLSLNRRALLLALQPFGPCLQETLLLPSPGSAPSQIALLKFSTHRAAAMAKKALVEGQSRLCGEQVAVEWLKPDLKQHFRQQLAGPSLRFLRPDVSQLTQTREKLGSQGARAALQLLCQRMKLGSPVFLTKCLGTGPAGWHRFWYQVVIPGHPVPFSGLIWVVLASDWQDGHEVAKDAVSAQLLEALSEPRTSLWSPGAEAGTMVKQ", "length": 352 }, "evidence": [ { "id": "E1BIG5", "url": "https://omabrowser.org/oma/group/E1BIG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYX4-1", "protein_name": "Dead end protein homolog 1", "gene_name": "DND1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100337502", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337502", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RWAKCPP", "url": "https://omabrowser.org/oma/group/RWAKCPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BII7", "url": "https://www.orthodb.org/?gene=E1BII7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005210713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210713", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BII7", "url": "https://www.uniprot.org/uniprotkb/E1BII7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BII7-1", "url": "https://www.uniprot.org/uniprotkb/E1BII7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRLETGANASSWVAASRRDEALPRAPDTSPAEEQSQGSGRGQRTCAGGGQRGSFGLQQPEGAGIREPPLSFKLKNDCVGAVIGRGGSNIKEIQSSTYTKIQIIRGYPEAEVRIFGTKAMQSKAKTVIDDLVKKQEEYKTESKLGVAAVQLSDGKDAMKDVSGEQKLIDWDKFRENILKWNEKKWAGLPPVKKNFYIESEKTSSMSQEQVDNWRKENYNIICDDLKDGEKRPLPNPTCNFEDAFHCYPEVMRNIEKAGFQKPTPIQSQAWPIILQGIDLIGVAQTGTGKTLSYLMPGFIHIDSQPVARNGPGMLVLTPTRELALQVDAECSEYSYRGLKSVCIYGGGDRDGQIKDLSKGADIIIATPGRLHDLQMNNFVYLKSITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPYAVRRLAQSYLKEPMIVYVGTLDLVAVSTVTQNIIVTTEDEKRSHIQAFIDSMSPKDKVIIFVSRKAVADHLSSDLGIRRISVESLHGNREQSDRERALKSFKTGKVRILIATDLASRGLDVHDVTHVYNYDFPRNIEEYVHRVGRTGRAGRTGVSITLITRNDWKIAGELINILERANQSVPEDLVSMAERYKANKLKKETENKWGRPQGKPRKFYH", "length": 643, "header": "tr|E1BII7-1|E1BII7_BOVIN Isoform 1 of RNA helicase OS=Bos taurus OX=9913 GN=DDX43 PE=3 SV=3 CANONICAL=E1BII7-1" }, "isoforms": [ { "isoform_ac": "E1BII7-1", "url": "https://www.uniprot.org/uniprotkb/E1BII7/entry#E1BII7-1", "sequence": { "sequence": "MSRLETGANASSWVAASRRDEALPRAPDTSPAEEQSQGSGRGQRTCAGGGQRGSFGLQQPEGAGIREPPLSFKLKNDCVGAVIGRGGSNIKEIQSSTYTKIQIIRGYPEAEVRIFGTKAMQSKAKTVIDDLVKKQEEYKTESKLGVAAVQLSDGKDAMKDVSGEQKLIDWDKFRENILKWNEKKWAGLPPVKKNFYIESEKTSSMSQEQVDNWRKENYNIICDDLKDGEKRPLPNPTCNFEDAFHCYPEVMRNIEKAGFQKPTPIQSQAWPIILQGIDLIGVAQTGTGKTLSYLMPGFIHIDSQPVARNGPGMLVLTPTRELALQVDAECSEYSYRGLKSVCIYGGGDRDGQIKDLSKGADIIIATPGRLHDLQMNNFVYLKSITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPYAVRRLAQSYLKEPMIVYVGTLDLVAVSTVTQNIIVTTEDEKRSHIQAFIDSMSPKDKVIIFVSRKAVADHLSSDLGIRRISVESLHGNREQSDRERALKSFKTGKVRILIATDLASRGLDVHDVTHVYNYDFPRNIEEYVHRVGRTGRAGRTGVSITLITRNDWKIAGELINILERANQSVPEDLVSMAERYKANKLKKETENKWGRPQGKPRKFYH", "length": 643, "header": "tr|E1BII7-1|E1BII7_BOVIN Isoform 1 of RNA helicase OS=Bos taurus OX=9913 GN=DDX43 PE=3 SV=3 CANONICAL=E1BII7-1" }, "locus": { "chromosome": "9", "start_pos": 12802324, "end_pos": 12786479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029077.8", "url": "https://www.ensembl.org/id/ENSBTAT00000029077.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029077.6", "url": "https://www.ensembl.org/id/ENSBTAP00000029077.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100337502", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337502", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X600-1", "protein_name": "RNA helicase", "gene_name": "DDX43", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSDWEESGDEAAEAPRPPPSSAVAAVSLWQLPATPRPSRAVGGEDRESGVAGSRRGRAARWRHPRAAAGRAQEEGEPLCFLISSALAGVLIGRGGAKIKELEESSGSRIQVIKGTSEAEVKIFGSAAVQNKAKVLIDETVVSCGQSNPRGKSLDVINPESTPKKPAINWASLRENRAKYEAMKWADLPPIEKNFYKESSRTACMSPEEVELWRKENNNIICDDLKEGEKRCIPNPVCKFEDVFEQYPDIMANIRKTGFQKPTPIQSQAWPIILQGIDLIGIAQTGTGKTLAYLMPGFIHLASQPIPKDKRGGPGMLVLAPTRELALQVEAECLKYTYKGFKSICIYGGGDRKAQINVVTKGVDIVIATPGRLNDLQMNNFINLKSITYLVLDEADRMLDMGFEPQIMKILIDVRPDRQTVMMSATWPDGVRRLAKSYLRNPMIVYVGTLDLAAVNTVEQKVIVINEEEKKAFMENFIDSMKPKDKAIIFVGKKSTADDIASDLGVQGVPVQSLHGDREQCDREQALDDFKKGKVRILVATDLASRGLDVHDITHVFNFDFPRNIEEYVHRVGRTGRAGRTGKAVTLITKKDWKAASELIDILQRAKQVVPDELISMAERYKQHQIRKEMEKDILRPQRKSP", "length": 641 }, "evidence": [ { "id": "E1BII7", "url": "https://omabrowser.org/oma/group/E1BII7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B8A609-1", "protein_name": "RNA helicase", "gene_name": "ddx43", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDWEDEYDGDGVAVSKQLTLPAKPAPVKSWRPPSPRGARNRETSSAGAKFGGDGEQWVNWRNRDSDFDVFDGAAGKNNSYSRSRIGPTRSRGYADRGDSSSVTLNVENSLVGRIIGRGGAKIRELQESSGASIKITRGAHEAEVLICGSCDAQHKAKDMIEDLVHENMGGSGYRNGNSSQGYQNNSCWSASAVKAAAAAAPAPTPIDWTSLRENRDKYEAMKWQDLPVLKKNFYIEAKSVAARSAEEVKIWRKENNNIFVDDLKDGDKRTIPNPVCTFEEAFAHYPGIMENIVRVGFKKPTPIQSQAWPVVLNGIDLIGIAQTGTGKTLAYLLPGFIHMDGQPMPRDKRNGPGMLVLTPTRELALQIEAECNKYSYKGFKSICIYGGGDRNAQIKVVTSGVDIVIATPGRLNDLQMNELINLRSITYLVLDEADRMLDMGFEPQIMKIILDIRPDRQTVMTSATWPPGVRRLAKSYLKDPMMVYVGTLDLAAVNTVQQTVLFVQEDEKKDYVFDFIHRMEPLDKVLIFVGKKLKADDLSSDLCLQGIAVQSLHGDREQCDREEALQDFKDGRVRILVATDLASRGLDVHDITHVFNYDFPRNVEEYVHRVGRTGRAGRSGESVTLVTREDWRVAAELITILERSGQDVPEELVLMAERYEKHRREKEMFGPRSGRGGGGGGGGRGGGWGGGGGGRGGGGGGGGGGRRGGYRGGSDLPF", "length": 719 }, "evidence": [ { "id": "E1BII7", "url": "https://omabrowser.org/oma/group/E1BII7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z6P9-1", "protein_name": "RNA helicase", "gene_name": "Ddx43", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRREPAANASSSGVAPRRSSTGSRGADRTATEETNRRGRVGSRGAGGGWREPAGAAEATAAGRREPPLCFGVKNDVVGAVIGRGGSKIREIQNTTNTRIQVIKGNPEAEIKIFGNKAMQTKAKTVIDNVVKKQQNYIPGQRVGIIAFQPTVGADTSTSESVTDDQPLIDWDQIREDALKWEKKKWADLPPIKKNFYIESATTSSMSQVQIDNWRKENFNITCDDLKDGEKRPIPNPICKFEDAFQSYPEVMENIKRAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLSYLMPGFIHLDSQPLAREQRNGPGMLVLTPTRELALQVEAECSKYSYGDLKSVCVYGGGDRDGQIQDVSKGVDIIIATPGRLNDLQMNNFVNLKSVTYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTIMTSATWPYAVRRLAQSYLKEPMIVYVGTLDLVAVSTVKQNIIITTEEEKRTHIQTFLENMSPKDKVIVFVSRKAVADHLSSDLILRHISVESLHGNREQSDREKALENFKTGKVRILIATDLASRGLDVHDITHVYNYDFPRNIEEYVHRVGRTGRAGRTGMSITLITRNDWRVATELINILERANQNIPEELVLMAERYKANKLKREMEKKMGRPQGKPQKFY", "length": 646 }, "evidence": [ { "id": "E1BII7", "url": "https://omabrowser.org/oma/group/E1BII7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R9C6-1", "protein_name": "RNA helicase", "gene_name": "Ddx43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRESAANASSSGVASRRSSTGSRGAERTATEEGNRRGRVGSRGAGGGWREPAGAAEATAASRREPPLCFGVKNDVVGAVIGRGGSKIREIQNTTNTRIQVIKGNPEAEIKIFGNKAMQTKAKTVIDNVVKKQQNYIPGHRVDIIAFQPTVGTDTSTSESVTDDQPLIDWDQIREDALKWEKKKWADLPPIKKNFYIESATTSSMSQVQIDNWRKENFNITCDDLKDGEKRPIPNPICKFEDAFHSYPEVMENIKRAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLSYLMPGFIHLDSQPLAREQRNGPGMLVLTPTRELALQVEAECSKYSYGDLKSVCVYGGGDRDGQIQDVSKGVDIIIATPGRLNDLQMNNFVNLKSVTYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTIMTSATWPYAVRRLAQSYLKEPMIVYVGTLDLVAVSTVKQNIIITTEEEKRTHIQTFLENMSPKDKVIVFVSRKAVADHLSSDLILRHISVESLHGNREQSDREKALENFKTGKVRILIATDLASRGLDVHDITHVYNYDFPRNIEEYVHRVGRTGRAGRTGMSITLITRNDWRIATELINILERANQNIPEELVLMAERYKANKLKREMEKKMGRPQGKPQKFY", "length": 646 }, "evidence": [ { "id": "E1BII7", "url": "https://omabrowser.org/oma/group/E1BII7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NXZ2-1", "protein_name": "Probable ATP-dependent RNA helicase DDX43", "gene_name": "DDX43", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHHGGAPKASTWVVASRRSSTVSRAPERRPAEELNRTGPEGYSVGRGGRWRGTSRPPEAVAAGHEELPLCFALKSHFVGAVIGRGGSKIKNIQSTTNTTIQIIQEQPESLVKIFGSKAMQTKAKAVIDNFVKKLEENYNSECGIDTAFQPSVGKDGSTDNNVVAGDRPLIDWDQIREEGLKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERANQSIPEELVSMAERFKAHQQKREMERKMERPQGRPKKFH", "length": 648 }, "evidence": [ { "id": "E1BII7", "url": "https://omabrowser.org/oma/group/E1BII7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1BII7", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BII7", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1BII7", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "E1BII7", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", 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"uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0A4", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1M0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A4" } ] } ] }, { "uniprot_ac": "A0A3Q1M155", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": 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"id": "A0AAA9SPF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPF3" } ] } ] }, { "uniprot_ac": "A0AAA9STQ6", "gene_name": "G3BP1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] } ] }, { "uniprot_ac": "A0AAA9SX42", "gene_name": "TDRD12", "activity": [ { "ec_number": 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] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": 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"id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P60712", "gene_name": "ACTB", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P60712" } ] } ] }, { "uniprot_ac": "P62739", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P62739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62739" } ] } ] }, { "uniprot_ac": "P63258", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "Q05B79", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": 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+ phosphate + H(+).", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "n ATP + n H2O + wound RNA = n ADP + n phosphate + unwound RNA.", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] } ] }, { "uniprot_ac": "Q0VCX2", "gene_name": "HSPA5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCX2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCX2" } ] } ] }, { "uniprot_ac": "Q0VD48", "gene_name": "VPS4B", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD48" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "Q0VD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD48" } ] } ] }, { "uniprot_ac": "Q17R09", "gene_name": "DHX38", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q17R09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R09" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q17R09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R09" } ] } ] }, { "uniprot_ac": "Q1LZ78", "gene_name": "NTPCR", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "Q1LZ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LZ78" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "Q1LZ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LZ78" } ] } ] }, { "uniprot_ac": "Q1RMT1", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q1RMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "Q1RMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT1" } ] } ] }, { "uniprot_ac": "Q28141", "gene_name": "DHX9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] } ] }, { "uniprot_ac": "Q29S22", "gene_name": "DDX47", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] } ] }, { "uniprot_ac": "Q2HJF8", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q2HJF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF8" } ] } ] }, { "uniprot_ac": "Q2KIZ8", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] } ] }, { "uniprot_ac": "Q2KJ94", "gene_name": "RAD51", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q2KJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ94" } ] } ] }, { "uniprot_ac": "Q2KJI7", "gene_name": "AFG3L2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] } ] }, { "uniprot_ac": "Q2NKY8", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKY8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKY8" } ] } ] }, { "uniprot_ac": "Q2NKZ1", "gene_name": "CCT7", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q2NKZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] }, { "ec_number": "5.6.1.7", "activity": "ATP + H2O + an unfolded polypeptide = ADP + phosphate + a folded polypeptide.", "evidence": [ { "id": "Q2NKZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] }, { "ec_number": "5.6.1.7", "activity": "", "evidence": [ { "id": "Q2NKZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] } ] }, { "uniprot_ac": "Q2NL08", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL08" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL08" } ] } ] }, { "uniprot_ac": "Q2NL22", "gene_name": "EIF4A3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] } ] }, { "uniprot_ac": "Q2T9X2", "gene_name": "CCT4", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q2T9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X2" } ] } ] }, { "uniprot_ac": "Q2TBP1", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2TBP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBP1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2TBP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBP1" } ] } ] }, { "uniprot_ac": "Q2TBU9", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2TBU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBU9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q2TBU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBU9" } ] } ] }, { "uniprot_ac": "Q32L40", "gene_name": "TCP1", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q32L40", "database": "UniProtKB", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002689669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689669", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BII8", "url": "https://www.uniprot.org/uniprotkb/E1BII8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BII8-1", "url": "https://www.uniprot.org/uniprotkb/E1BII8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKQTERRRSWGQRSWSTTEGEDAAQEVGSQSHRRSICSVGGRSGSQASIPPWIEGNYNYYIEEDEDGEEEEELWKDEPAEEEDRQPGEAAATTERAEGGGADTPLVSTTLNVNVGGHSYHLDYTELACYPKTRLGRLATSTSRSRQLGLCDDYEVQTDEYFFDRDPEVFQLIYNFYSSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDDLSEQLKIQRELRAQAQAEEAEELFQDMRFYGAQRRRLWNLMEKPFSSVAAKAIGVASSLFVLISVVALALNTVEEMQQQPERGEGGGNPRPFLEHVETLCMAFFTLEFLLRLASTPDLRRFARSALNLVDLVAILPLYLQLLLECFTSEDQLHVKGSPREHDLETMGRVGKVGQVLRVMRLLRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGILTFAAAVYSVEHDVQGTNFTSIPHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGNVEFLQRAGKKIAECLAGSNSQATPRLNS", "length": 566, "header": "tr|E1BII8-1|E1BII8_BOVIN Isoform 1 of Potassium voltage-gated channel subfamily V member 2 OS=Bos taurus OX=9913 GN=KCNV2 PE=3 SV=2 CANONICAL=E1BII8-1" }, "isoforms": [ { "isoform_ac": "E1BII8-1", "url": "https://www.uniprot.org/uniprotkb/E1BII8/entry#E1BII8-1", "sequence": { "sequence": "MLKQTERRRSWGQRSWSTTEGEDAAQEVGSQSHRRSICSVGGRSGSQASIPPWIEGNYNYYIEEDEDGEEEEELWKDEPAEEEDRQPGEAAATTERAEGGGADTPLVSTTLNVNVGGHSYHLDYTELACYPKTRLGRLATSTSRSRQLGLCDDYEVQTDEYFFDRDPEVFQLIYNFYSSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDDLSEQLKIQRELRAQAQAEEAEELFQDMRFYGAQRRRLWNLMEKPFSSVAAKAIGVASSLFVLISVVALALNTVEEMQQQPERGEGGGNPRPFLEHVETLCMAFFTLEFLLRLASTPDLRRFARSALNLVDLVAILPLYLQLLLECFTSEDQLHVKGSPREHDLETMGRVGKVGQVLRVMRLLRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGILTFAAAVYSVEHDVQGTNFTSIPHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGNVEFLQRAGKKIAECLAGSNSQATPRLNS", "length": 566, "header": "tr|E1BII8-1|E1BII8_BOVIN Isoform 1 of Potassium voltage-gated channel subfamily V member 2 OS=Bos taurus OX=9913 GN=KCNV2 PE=3 SV=2 CANONICAL=E1BII8-1" }, "locus": { "chromosome": "8", "start_pos": 41761077, "end_pos": 41747616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023770.3", "url": "https://www.ensembl.org/id/ENSBTAT00000023770.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023770.3", "url": "https://www.ensembl.org/id/ENSBTAP00000023770.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:784234", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784234", "resource": "KEGG Pathway" }, { "id": "R-BTA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YCX9-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "KCNV2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLQLNMRRQFPFLKHKGREVPSIITQPNMGKDNEGVCLNKQSDFSGTAPLSSQPLLLLGPEGNYNYYVDDEDEEEEEKDQGKWPTGDRFEGENKLSSSIPFSPAFSSGAPARPSTPSVLNINVGGQSYRLTYQAVATYPKTRLGRLATSTDRRCQLGLCDDYAAQVDEYFFDRDPAVFQLVYNFYASGVLRVRDELCPRSFLEELSYWGVRLKYTPRCCRICFEERRDELSEQLKVQRELRSQAEAQENEQLFHHMRYYGPQRWRLWNLMEKPFSSVTAKVMAVASSFFVLISVVALALNTVEEMQQVDRKSGESRPVLEHIETLCIVFFTLEYLLRLVSTPDLRRFASSALNAVDLIAILPLYLQLLLECFTDDDQPRGRGSQHEYDIEKVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFAFSAMVYTVEHDVSSTNFTSIPHAWWWAAVSISTVGYGDMCPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTALKKERGKVDFTRRAMKKISECCGEGGARSLPQHG", "length": 570 }, "evidence": [ { "id": "E1BII8", "url": "https://omabrowser.org/oma/group/E1BII8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZZR6-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "Kcnv2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKQSTERRWSLSYKLWNTSETEDVPNTGSNQHRKSICSMGARTGSQASIAPQWTEGNYNYYIEEDEDCGEEEDWKDDLAEENQKPEGPPAPLDGHTDTPTQLSTLKVNVGGHSYQLECCELANYPKTRLGRLVTSTSRNCQLGLCDDYEAKTDEYFFDRDPAVFQLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDELSEQLKIQRELRAQAQAEEAEELFRDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVASNLFVLISVVALALNTVEEMQHQAEQGTGGGDPRPILEHVEMLCVAFFTLEFLLRLASTPNLRRFARSALNLVDLVAILPFYLQLLLECFTSEDQRHGKGSPREHDLETVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSAAVYSVEHDVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGKVNFMQRATKKMAECLSGSNAQSATRQEN", "length": 561 }, "evidence": [ { "id": "E1BII8", "url": "https://omabrowser.org/oma/group/E1BII8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q6N3-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "kcnv2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKLKGRRQSLFPNYKLGVTVPAPKDPEDSDLPFGQHNWVKPWNSMQELSKDIYDIYAEYEDDEEDRLFSTPSKLSSPVKNYMLNINVGGKVYQISYRVAAKYPKTRIGRLATYTDHNRKLDLCDDYTVHNNEFFFDRDPDVFHNIFNFYRTGVLWIKDELCPRNFLEEINYWGVRIKNTHRCCRISFEERQDELNEQLKVQRELEAEVETEEHEDLFQDMAFGHTRFLIWNMMEKPFSSIIAKIMAVASSFFVLVSLVAMTLNTVEEMQYITTNGQLSGKTYCEYVETFCIAFFTMEYLLRLVSTPDLTRFGRSVLNAVDLIAILPLYLQMVLESFESHDYWKHGSDIETVGRVGKLGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLFLFIAMGILTFSAMVYTVEHDVHKTNFTSIPHAWWWAAVSISTVGYGDMFPETHLGRIFAFACISFGIILNGMPISILFNKFSDYYSKLKAYEYTSSIKNRGKVRFVKRAAKRFAECF", "length": 518 }, "evidence": [ { "id": "E1BII8", "url": "https://omabrowser.org/oma/group/E1BII8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3IIK0-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "Kcnv2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLKQSNERRLSLGYIPWSIPETEEVSNARSKQHRRSICSLGARTGSQASITPPWTEGNYNYYIEEDEDGGEDGEDWKDDLAEEKQPPECPTALLDDHTDTPAQLSTLKVNVGGHSYQLEWCELANYPKTRLGRLVTSTSRSRQLGLCDDYEAQTDEYFFDRDPAVFHLIYNFYISGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDELSEQLKIQRELRAQAQAEEAEELFRDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVASNLFVLISVVALALNTVEEMQHQAEEGTGGGDPRPILEHVEMLCVAFFTLEFVLRLASTPNLRGFARSALNLVDLVAILPFYLQLLLECFTSEDQREGKDSQREHDLETVGRVGKVGQVLRLMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSAAVYSVEHDVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGKVNFMQRATKKMAQCLSGSNTQPTIRQEN", "length": 562 }, "evidence": [ { "id": "E1BII8", "url": "https://omabrowser.org/oma/group/E1BII8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8CFS6-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "Kcnv2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKQSNERRWSLSYKPWSTPETEDVPNTGSNQHRRSICSLGARTGSQASIAPQWTEGNYNYYIEEDEDCGEEGEDWKDDLAEENQKAECLTSLLDGHNDTPAQMSTLKVNVGGHSYLLECCELANYPKTRLGRLATSTTRRGQLGLCDDYEAQTDEYFFDRDPAVFQLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDELSEQLKIQRELRAQAQAEEAEELFRDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVATNLFVLISVVALALNTVEEMQHQAEQGTGGGDPRPILEHVEMLCVAFFTLEFLLRLASTPNLQRFARSALNLVDLVAILPFYLQLLLECFTSEDQRHNKDSPREHDLETVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSAAVYSVEHDVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGKVNFMQRATKKMAECLSESHAQSTTRQEN", "length": 562 }, "evidence": [ { "id": "E1BII8", "url": "https://omabrowser.org/oma/group/E1BII8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TDN2-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "KCNV2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKQSERRRSWSYRPWNTTENEGSQHRRSICSLGARSGSQASIHGWTEGNYNYYIEEDEDGEEEDQWKDDLAEEDQQAGEVTTAKPEGPSDPPALLSTLNVNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQLSLCDDYEEQTDEYFFDRDPAVFQLVYNFYLSGVLLVLDGLCPRRFLEELGYWGVRLKYTPRCCRICFEERRDELSERLKIQHELRAQAQVEEAEELFRDMRFYGPQRRRLWNLMEKPFSSVAAKAIGVASSTFVLVSVVALALNTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFFTLEYLLRLASTPDLRRFARSALNLVDLVAILPLYLQLLLECFTGEGHQRGQTVGSVGKVGQVLRVMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVEHDVPSTNFTTIPHSWWWAAVSISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTTIRRERGEVNFMQRARKKIAECLLGSNPQLTPRQEN", "length": 545 }, "evidence": [ { "id": "E1BII8", "url": "https://omabrowser.org/oma/group/E1BII8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BII8", "url": "https://www.uniprot.org/uniprotkb/E1BII8" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "E1BII8", "url": "https://www.uniprot.org/uniprotkb/E1BII8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "E1BII8", "url": "https://www.uniprot.org/uniprotkb/E1BII8" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "E1BII8", "url": "https://www.uniprot.org/uniprotkb/E1BII8" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "E1BII8", "url": "https://www.uniprot.org/uniprotkb/E1BII8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "E1BII8", "url": "https://www.uniprot.org/uniprotkb/E1BII8" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "E1BII8", "url": "https://www.uniprot.org/uniprotkb/E1BII8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BII8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 566, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BII8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BII8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BII8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII8" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 276, "end_pos": 523, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BII8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII8" }, { "id": "PF02214", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel tetramerisation-type BTB", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 205, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 461, "end_pos": 463 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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rod domain-containing protein", "type": "recommended", "evidence": [ { "id": "E1BIL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIL2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIL2", "url": "https://www.uniprot.org/uniprotkb/E1BIL2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KRT76", "url": "https://www.uniprot.org/uniprotkb/E1BIL2", "locus": { "chromosome": "5", "start_pos": 27166047, "end_pos": 27157755, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038033", "url": "https://www.ensembl.org/id/ENSBTAG00000038033" } ] } } ], "crossref": [ { "id": "E1BIL2", "url": "https://alphafold.ebi.ac.uk/entry/E1BIL2", "database": "AlphaFoldDB", "categories": 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"MSRQAGYSQQSCRASSGSRRQGFSGHSAVVSGQSRVTSSKSSLASRSGGGGAGSAACALMGGGFGSQSLYNLGGNKKISISLAGGSIRAGGFRSTSGGYSGGCGFGGGGRGMGGGFGGRAGGFGGGVGGFGGPGGFPGGIQEVTVNQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWSLLQEQGSGTNTNNRNLEPFFENYISSLRAFLDGLHVEKDKLHEELRSMEGMVEDFKKRYEEEINKRTAAENDFVVLKKDIDAAYMTKVELEAKVDSVTDEINFLKALYDAELSQMQLDTGDTSVVLSMDNNRCLDLDSIIAEVRAQYEAIAQRSKAEAEALYQSKLGELQTTAGMHGDDLKSIKTEIMEFNRMIQRLRAEIESVKKQNANLQTAIADAEQHGEVALKDANAKLQDLKAALQQAKEDLARLLKEYQELMNVKLALDIEIATYRTLLEGEECRMSGECQSSVSIEMVHNTTSSSSGGSGALGGGAGGRGGLGSGGLGSGSLGSGRLGSGGRDSRASRGGLGLDSSSGGGSAVRGGVSNSGGSCAVSGVGGRSSVRVTQSSSQSQRSHHKL", "length": 599, "header": "tr|E1BIL2-1|E1BIL2_BOVIN Isoform 1 of IF rod domain-containing protein OS=Bos taurus OX=9913 GN=KRT76 PE=3 SV=3 CANONICAL=E1BIL2-1" }, "locus": { "chromosome": "5", "start_pos": 27197009, "end_pos": 27188573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000040353.5", "url": "https://www.ensembl.org/id/ENSBTAT00000040353.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040129.4", "url": "https://www.ensembl.org/id/ENSBTAP00000040129.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "E1BIL2", "url": "https://www.uniprot.org/uniprotkb/E1BIL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIL2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 599, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIL2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIL2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIL2" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 168, "end_pos": 483, "start_aa": "Glu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 498, "end_pos": 500 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIM6-1", "uniprot_ac": "E1BIM6", "uniprot_id": "E1BIM6_BOVIN", "mass": { "chemical_mass": 47218.0, "monoisotopic_mass": 47218.0 }, "refseq": { "ac": "NP_001179283", "name": "neuronal pentraxin-1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179283" }, "gene_names": [ { "name": "NPTX1", "type": "recommended", "evidence": [ { "id": "E1BIM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM6" } ] }, { "name": "NPTX1", "type": "synonym", "evidence": [ { "id": "NP_001179283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179283" } ] } ], "protein_names": [ { "name": "Neuronal pentraxin 1", "type": "synonym", "evidence": [ { "id": "E1BIM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM6/entry#names_and_taxonomy" } ] }, { "name": "neuronal pentraxin-1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001179283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179283" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIM6", "url": "https://www.uniprot.org/uniprotkb/E1BIM6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NPTX1", "url": "https://www.uniprot.org/uniprotkb/E1BIM6", "locus": { "chromosome": "19", "start_pos": 52066350, "end_pos": 52059956, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008940", "url": "https://www.ensembl.org/id/ENSBTAG00000008940" } ] } } ], "crossref": [ { "id": "E1BIM6", "url": "https://alphafold.ebi.ac.uk/entry/E1BIM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008940", "url": 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{ "id": "bta:513538", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513538", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GDMCAAT", "url": "https://omabrowser.org/oma/group/GDMCAAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIM6", "url": "https://www.orthodb.org/?gene=E1BIM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19277:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19277:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179283", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179283", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BIM6", "url": "https://www.uniprot.org/uniprotkb/E1BIM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIM6-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAGRAARTCALLALCFLGSGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSNVLQLRETVLQQKETILSQKETIRELTTKLGRCESQSTLDASAGEARTGGGRKQPGSGKNTMGDLSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDDLERQVLSRVNTLEEGKGGPKNDTEERVKIESALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSAAPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICITWTTRDGVWEAYQDGTQGGNGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSTKALSGNVIAWAESHIEIYGGATKWTFEACRQIN", "length": 432, "header": "tr|E1BIM6-1|E1BIM6_BOVIN Isoform 1 of Neuronal pentraxin 1 OS=Bos taurus OX=9913 GN=NPTX1 PE=4 SV=1 CANONICAL=E1BIM6-1" }, "isoforms": [ { "isoform_ac": "E1BIM6-1", "url": "https://www.uniprot.org/uniprotkb/E1BIM6/entry#E1BIM6-1", "sequence": { "sequence": "MPAGRAARTCALLALCFLGSGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSNVLQLRETVLQQKETILSQKETIRELTTKLGRCESQSTLDASAGEARTGGGRKQPGSGKNTMGDLSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDDLERQVLSRVNTLEEGKGGPKNDTEERVKIESALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSAAPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICITWTTRDGVWEAYQDGTQGGNGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSTKALSGNVIAWAESHIEIYGGATKWTFEACRQIN", "length": 432, "header": "tr|E1BIM6-1|E1BIM6_BOVIN Isoform 1 of Neuronal pentraxin 1 OS=Bos taurus OX=9913 GN=NPTX1 PE=4 SV=1 CANONICAL=E1BIM6-1" }, "locus": { "chromosome": "19", "start_pos": 52065751, "end_pos": 52060090, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011769.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011769.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011769.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011769.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:513538", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513538", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RZA8-1", "protein_name": "Neuronal pentraxin 1", "gene_name": "NPTX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPAGPAARTCALLALCLLGSGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSNVLQLRETVLQQKETILSQKETIRELTTKLGRCESQSTLDASAGEARAGGGRKQPGSGKNTMGDLSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDDLERQVLSRVNTLEEGKGGPRNDTEERVKIESALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKATAAPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICITWTTRDGVWEAYQDGTQGGNGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVASWPISTSGTAS", "length": 385 }, "evidence": [ { "id": "E1BIM6", "url": "https://omabrowser.org/oma/group/E1BIM6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P47971-1", "protein_name": "Neuronal pentraxin-1", "gene_name": "Nptx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAGRAARTCALLALCLLGSRAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSNVLQLRETVLQQKETILSQKETIRELTTKLGRCESQSTLDAGPGEARSGGGRKQPGSGKNTMGDLSRTPASETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDDLERQVLSRVNTLEEGKGGPKNDTEERAKIESALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSAAPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGNGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSSKALSGNVIAWAESQIEIFGGATKWTFEACRQIN", "length": 432 }, "evidence": [ { "id": "E1BIM6", "url": "https://omabrowser.org/oma/group/E1BIM6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15818-1", "protein_name": "Neuronal pentraxin-1", "gene_name": "NPTX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAGRAARTCALLALCLLGAGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSSVLQLRETVLQQKETILSQKETIRELTAKLGRCESQSTLDPGAGEARAGGGRKQPGSGKNTMGDLSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDELERQVLSRVNTLEEGKGGPRNDTEERVKIETALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSATPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGSGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSTKALSGNVIAWAESHIEIYGGATKWTFEACRQIN", "length": 432 }, "evidence": [ { "id": "E1BIM6", "url": "https://omabrowser.org/oma/group/E1BIM6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62443-1", "protein_name": "Neuronal pentraxin-1", "gene_name": "Nptx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAGRAARTCALLALCLLGSGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSNVLQLRETVLQQKETILSQKETIRELTTKLGRCESQSTLDSGPGEARSGGGRKQPGSGKNTMGDLSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDDLERQVLSRVNTLEEGKGGPKNDTEERAKIESALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSAAPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGNGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSSKALSGNVIAWAESQIEIFGGATKWTFEACRQIN", "length": 432 }, "evidence": [ { "id": "E1BIM6", "url": "https://omabrowser.org/oma/group/E1BIM6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BIM6", "url": "https://www.uniprot.org/uniprotkb/E1BIM6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BIM6", "url": "https://www.uniprot.org/uniprotkb/E1BIM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "axonogenesis involved in innervation", "id": "GO:0060385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060385", "evidence": [ { "database": "UniProtKB", "id": "E1BIM6", "url": "https://www.uniprot.org/uniprotkb/E1BIM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIM6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 432, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIM6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIM6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM6" }, { "id": "PS51828", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51828" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pentraxin (PTX)", "eco_id": "ECO_0000259", "start_pos": 226, "end_pos": 428, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 193, "end_pos": 195 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIN1-1", "uniprot_ac": "E1BIN1", "uniprot_id": "E1BIN1_BOVIN", "mass": { "chemical_mass": 142943.0, "monoisotopic_mass": 142943.0 }, "refseq": { "ac": "NP_001193591", "name": "SCL-interrupting locus protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193591" }, "gene_names": [ { "name": "STIL", "type": "recommended", "evidence": [ { "id": "E1BIN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIN1" } ] }, { "name": "STIL", "type": "synonym", "evidence": [ { "id": "NP_001193591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193591" } ] } ], "protein_names": [ { "name": "SCL-interrupting locus protein", "type": "synonym", "evidence": [ { "id": "NP_001193591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193591" } ] }, { "name": "SCL/TAL1 interrupting locus", "type": "synonym", "evidence": [ { "id": "NP_001193591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193591" } ] }, { "name": "STIL centriolar assembly protein", "type": "synonym", "evidence": [ { "id": "E1BIN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIN1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIN1", "url": "https://www.uniprot.org/uniprotkb/E1BIN1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "STIL", "url": "https://www.uniprot.org/uniprotkb/E1BIN1", "locus": { "chromosome": "3", "start_pos": 98990375, "end_pos": 98936610, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017844", "url": "https://www.ensembl.org/id/ENSBTAG00000017844" } ] } } ], "crossref": [ { "id": "ENSBTAG00000017844", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017844", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510012", "url": "https://www.ncbi.nlm.nih.gov/gene/510012", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510012", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510012", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BIN1", "url": "https://www.orthodb.org/?gene=E1BIN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15128", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15128", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15128:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15128:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26399", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26399", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193591", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193591", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BIN1", "url": "https://www.uniprot.org/uniprotkb/E1BIN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIN1-1", "url": "https://www.uniprot.org/uniprotkb/E1BIN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESTYPLAGPQINTRFSSSRMVPFYFPPSKCALWNPVPIGDFIYLHLRYYRNPRLVVTEKTIRLACRHAKQNKNNLPCFLLGSLTVDEDEESMTLTVDRFDPGREVPELLERIPTASLPGDFVIPCKIHTQGLCSREIITHNADDFNSSFKALQHHVCSKEPLDCGKLLALRAHITSKESLDTVDFDLDWAAVTLANTFKCTPVKPISIIPTALARNLSSNLNISQVQGTYKYGYLTMDETRKLLLLLESDPKVYSLPLVGIWLSGIIHIYSPQVWACCLRYMFSSSIQERVFSESGNFIIVLYSVTHKDPEFYECLPCDGRLPDLRFQLLTSKETLRLFKNVEPSDKNPVCFELSAEDQNAEREFFKKVSKNLSIKSSSQKLPPGKMPTNDHDSGVEDEDVSPRPIPSPHPVSQKVSKIQPSVPELSLVLDENSIEPTPVPNPLEMVNNENPPLLINHAEHLEQSQPQLCDEKHRPEAEAGEPSFRGLPNPLNQDTAPLRHCKVRQLSTCKKGNSHIRNSSKPSFNGLSSDTSEKLQTVSAANVHKEEYPVRSSTFNSKQSSLAPQSHPHNFVFSLHNSGRPMEFQIPTPQPPSYYSTNVCSCCQHHGHIQYSPINSWQGMNTVGSVQDLKSETLHKHSLFHPSGCPAQYHNAFFSSSSPIALRPQGNMRGCSSDSNVEPSPAARLPPHVDFCSPWPCAVCMHTPKTGSDDGMMGLSPDAYRFITEQDRQLRLLQAQIQRLLEAQSLQPCSPKTTTVEDTTQAARQMELVSMEAQSPPALHMRKSVSIAVSTGASLFWNAAGDHQEPESQLRQDDTKISSEDMNFSVDINNEVTSTPGSASSLKAVDIPSFEESNVAVEEEFNQQLCISNSSSPLERKEPDVPVFFPNPLQAECGSMCFQSGPTEGATNSSGTSGEPQTEQVMQPLPHQPSDNQQLFQDVLSQGNHLLNNSPKVTEEPSTKAVIISDECTKNQNVYHTKKKKHDPGSVDKECVLNATLKQLRSFGVKIDSPTKVKKNAHKVDHASVLACISPEAVISGLNYMSFANVGMSGLSPSGVDLSMEANAIALKYLNENQLSQLSLTRSSQNNGDSPFSLLHINTDRSTVGLSLISPNNMSFATKKYMKRYGLIQSSDNSEDEEEPPNNTDGKSEHLVNQNLTYIAEQLDCQKEPSRNAGEITDCSNCDSMGTHTGTPVLRNITNEAVQPKATQQLNENPTFLLKNLKPSPAMNLRIGKAEFTQHPEKENVRDTPIFPESLKPSETLKQMNSMNSVGTFLDVKRLRQLPKLF", "length": 1288, "header": "tr|E1BIN1-1|E1BIN1_BOVIN Isoform 1 of STIL centriolar assembly protein OS=Bos taurus OX=9913 GN=STIL PE=4 SV=5 CANONICAL=E1BIN1-1" }, "isoforms": [ { "isoform_ac": "E1BIN1-1", "url": "https://www.uniprot.org/uniprotkb/E1BIN1/entry#E1BIN1-1", "sequence": { "sequence": 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"length": 1288, "header": "tr|E1BIN1-1|E1BIN1_BOVIN Isoform 1 of STIL centriolar assembly protein OS=Bos taurus OX=9913 GN=STIL PE=4 SV=5 CANONICAL=E1BIN1-1" }, "locus": { "chromosome": "3", "start_pos": 98989676, "end_pos": 98940131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023728.8", "url": "https://www.ensembl.org/id/ENSBTAT00000023728.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023728.8", "url": "https://www.ensembl.org/id/ENSBTAP00000023728.8" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 439, "start_aa": "Thr", "end_pos": 439, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr439", "evidence": [ { "id": "", "database": "GlyGen", 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"length": 838, "header": "tr|E1BIP5-1|E1BIP5_BOVIN Isoform 1 of RBR-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=RNF19A PE=3 SV=1 CANONICAL=E1BIP5-1" }, "locus": { "chromosome": "14", "start_pos": 64101867, "end_pos": 64075482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023707.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023707.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023708.5", "url": "https://www.ensembl.org/id/ENSBTAP00000023708.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 434, "start_aa": "Thr", "end_pos": 434, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr434", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540195", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540195", "resource": "KEGG Pathway" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YCS7-1", "protein_name": "RBR-type E3 ubiquitin transferase", "gene_name": "RNF19A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRFNPLLMSDLDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISLGSLFRRKKDTKRKSRDLNGGVDGIASIESIHSEMCTDKNSIFSTCTSSDNGTTSSSKPSGDFMECPLCLLRHSKDRFPEIMTCHHRSCVDCLRQYLRIEISESRVNISCPECSERFNPHDIRLILNDDILMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNAAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDREGNSMEVQVDIESKPAKFRHNSGSSSVDDGSAAGRSNAACSSACVPESKSGATKWSKETTAGKKCKGKLRKKSSMKINETREDMDAQLLEQQSTNSSEFDSPSLSDSIPSVADSHSSHFSEFSCSDMESMKTSCSHGSSDYHTRFTTVSVLPEVENDRLENSPQASGIPMPVPAAPGTDVQQLSYIAEESINNGSSTDVGLGVDETLKEANNNHSQRAAELSAAIQTEI", "length": 819 }, "evidence": [ { "id": "E1BIP5", "url": "https://omabrowser.org/oma/group/E1BIP5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LLQ3-1", "protein_name": "RBR-type E3 ubiquitin transferase", "gene_name": "Rnf19a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEQEISFIFKYNEGLCMNIDSDSVLMSILDMSLHQQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELTGGVDGIASIESIRSEVCAEKNSIFSTNASSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAIDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGTMRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERCSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDRITTFTLTQRFFIVVTWIRREREGNSMEVQVDIESKPFKFRHHSGSSSVDDGGAARGHASGSSSGLPEGKSSATKWSKEATGGKKSKSGKLRKKGNTKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMRTSCSHGSSDCHARFTAVNTLPEVENDRLENSPHQCSGSLLSKTASCSEVPQPSHAADERATSSGGGKAAVDVCFGDALRETNNNHSHQAADLKVAVQTEI", "length": 861 }, "evidence": [ { "id": "E1BIP5", "url": "https://omabrowser.org/oma/group/E1BIP5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P50636-1", "protein_name": "E3 ubiquitin-protein ligase RNF19A", "gene_name": "Rnf19a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQEQEISFIFKYNEGLCMNIDSDSILMSILDMSLHQQMGSDRDLQSSTSSVSLPSVKKAPKQRRISIGSLFRRKKDSKRKSRELNGGVDGIASIESIHSEMCADKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNAAIDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGTIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERCSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDREGNSMEVQVDIESKPFKFRHNSGSSSVDDSGATRGHTGGASSGLPEGKSSATKWSKEATGGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMRTSCSHGSSDCHARFTAVNTLPEVENDRLENSPHQCSSALLSKAASCSDVPQPSHAADEHGTSRSGGKPMVDLCFGDALRETNNNHSHQTADLKVAVQTEI", "length": 840 }, "evidence": [ { "id": "E1BIP5", "url": "https://omabrowser.org/oma/group/E1BIP5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2VJ60-1", "protein_name": "E3 ubiquitin-protein ligase RNF19A", "gene_name": "RNF19A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQEQEIGLLSKYNEGLCINTDPNSILMSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKENKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPEIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSAARSHPGGLSGGLPEGKSSATKWSKEATAGKKSKSGKLRKKSNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSTDYHARFATVNILPEVENDRLENSPHQCSISVLTKTASCSEDPQLNHIAEEHSNNGIRPNVDLYFGNALKETNNNHSHQTMELKVAIQTDI", "length": 838 }, "evidence": [ { "id": "E1BIP5", "url": "https://omabrowser.org/oma/group/E1BIP5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9NV58-1", "protein_name": "E3 ubiquitin-protein ligase RNF19A", "gene_name": "RNF19A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVVTQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI", "length": 838 }, "evidence": [ { "id": "E1BIP5", "url": "https://omabrowser.org/oma/group/E1BIP5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BIP5", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BIP5", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "E1BIP5", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BIP5", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BIP5", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "E1BIP5", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BIP5", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "E1BIP5", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" }, { "start_pos": 822, "end_pos": 824, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983140" } ] }, { "id": "R-BTA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4I9-1", "E1BJS7-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q1JQA1-1", "Q29RQ5-1", "Q32LN5-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0AAA9RXI4-1", "Q4U5R4-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983147" } ] }, { "id": "R-BTA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983156" } ] }, { "id": "R-BTA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1MAR8", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] } ] }, { "uniprot_ac": "A0A3Q1MLB6", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] } ] }, { "uniprot_ac": "A0A3Q1MLH2", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] } ] }, { "uniprot_ac": "A0A3Q1N3G7", "gene_name": "TRIM36", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] } ] }, { "uniprot_ac": "A0AAA9RXI4", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] } ] }, { "uniprot_ac": "A0AAA9RXX2", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] } ] }, { "uniprot_ac": "A0AAA9RZ14", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] } ] }, { "uniprot_ac": "A0AAA9S100", "gene_name": "MKRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] } ] }, { "uniprot_ac": "A0AAA9TKS8", "gene_name": "RNF217", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] } ] }, { "uniprot_ac": "A0AAA9TWH7", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] } ] }, { "uniprot_ac": "A0AAF6DMH9", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] } ] }, { "uniprot_ac": "A0ABI0NWC8", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] } ] }, { "uniprot_ac": "A0JN74", "gene_name": "TRIM11", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] } ] }, { "uniprot_ac": "A1A4I9", "gene_name": "UFL1", "activity": [ { "ec_number": "2.3.2.-", "activity": "", "evidence": [ { "id": "A1A4I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I9" } ] } ] }, { "uniprot_ac": "A3KN22", "gene_name": "UBE2M", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] } ] }, { "uniprot_ac": "A5D7F8", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] } ] }, { "uniprot_ac": "A5PJC4", "gene_name": "UBE2L6", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] } ] }, { "uniprot_ac": "A5PKG6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] } ] }, { "uniprot_ac": "A6H795", "gene_name": "UBE2W", "activity": [ { "ec_number": "2.3.2.25", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein].", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] } ] }, { "uniprot_ac": "E1B782", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] } ] }, { "uniprot_ac": "E1B7D3", "gene_name": "TRIM39", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] } ] }, { "uniprot_ac": "E1B7G3", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] } ] }, { "uniprot_ac": "E1B7Q7", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] } ] }, { "uniprot_ac": "E1B8R6", "gene_name": "ARIH2", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] } ] }, { "uniprot_ac": "E1BAV2", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] } ] }, { "uniprot_ac": "E1BBN5", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] } ] }, { "uniprot_ac": "E1BBY2", "gene_name": "TRIM41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] } ] }, { "uniprot_ac": "E1BCU1", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] } ] }, { "uniprot_ac": "E1BCW1", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] } ] }, { "uniprot_ac": "E1BH71", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] } ] }, { "uniprot_ac": "E1BID7", "gene_name": "TRIM69", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] } ] }, { "uniprot_ac": "E1BIP5", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] } ] }, { "uniprot_ac": "E1BIW0", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] } ] }, { "uniprot_ac": "E1BJS7", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] } ] }, { "uniprot_ac": "E1BL26", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] } ] }, { "uniprot_ac": "E1BNQ6", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] } ] }, { "uniprot_ac": "E1BNY9", "gene_name": "HUWE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] } ] }, { "uniprot_ac": "F1MBM6", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] } ] }, { "uniprot_ac": "F1MEX6", "gene_name": "RNF19B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] } ] }, { "uniprot_ac": "F1MJ10", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] } ] }, { "uniprot_ac": "F1MJS5", "gene_name": "HECTD3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] } ] }, { "uniprot_ac": "F1MLS5", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] } ] }, { "uniprot_ac": "F1MM41", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] } ] }, { "uniprot_ac": "F1MTS8", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] } ] }, { "uniprot_ac": "F1MWS4", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] } ] }, { "uniprot_ac": "F1MYL0", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] } ] }, { "uniprot_ac": "F1N1X8", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] } ] }, { "uniprot_ac": "F1N3I3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] } ] }, { "uniprot_ac": "F1N495", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] } ] }, { "uniprot_ac": "F1N5G3", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] } ] }, { "uniprot_ac": "F1N645", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] } ] }, { "uniprot_ac": "F1N6G5", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] } ] }, { "uniprot_ac": "F1N703", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] } ] }, { "uniprot_ac": "F1N7A0", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] } ] }, { "uniprot_ac": "P61085", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] } ] }, { "uniprot_ac": "Q0II22", "gene_name": "RNF126", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] } ] }, { "uniprot_ac": "Q0P5K3", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] } ] }, { "uniprot_ac": "Q17QG5", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] } ] }, { "uniprot_ac": "Q1JQA1", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] } ] }, { "uniprot_ac": "Q1RML1", "gene_name": "UBE2S", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] } ] }, { "uniprot_ac": "Q1RMW1", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] } ] }, { "uniprot_ac": "Q1RMX2", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] } ] }, { "uniprot_ac": "Q29RQ5", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] } ] }, { "uniprot_ac": "Q2T9X7", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] } ] }, { "uniprot_ac": "Q2TA03", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] } ] }, { "uniprot_ac": "Q2TA10", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] } ] }, { "uniprot_ac": "Q32L27", "gene_name": "UBE2Q2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] } ] }, { "uniprot_ac": "Q32LN1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] } ] }, { "uniprot_ac": "Q32LN5", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] } ] }, { "uniprot_ac": "Q32P99", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] } ] }, { "uniprot_ac": "Q32PA5", "gene_name": "UBE2C", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] } ] }, { "uniprot_ac": "Q3MHP1", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] } ] }, { "uniprot_ac": "Q4U5R4", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] } ] }, { "uniprot_ac": "Q5E9J6", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] } ] }, { "uniprot_ac": "Q7YRV4", "gene_name": "TRIM21", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIP5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 838, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIP5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIP5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.31", "ec_name": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "2.3.2.31", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.31" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 434 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 173, "end_pos": 175 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 590, "end_pos": 592 }, { "start_pos": 687, "end_pos": 689 }, { "start_pos": 704, "end_pos": 706 }, { "start_pos": 822, "end_pos": 824 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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{ "uniprot_canonical_ac": "E1BIP7-1", "uniprot_ac": "E1BIP7", "uniprot_id": "E1BIP7_BOVIN", "mass": { "chemical_mass": 27221.0, "monoisotopic_mass": 27221.0 }, "refseq": { "ac": "XP_002696732", "name": "mast cell protease 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696732" }, "gene_names": [ { "name": "LOC540321", "type": "recommended", "evidence": [ { "id": "E1BIP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP7" } ] }, { "name": "LOC540321", "type": "synonym", "evidence": [ { "id": "XP_002696732", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696732" } ] } ], "protein_names": [ { "name": "Peptidase S1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "E1BIP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP7/entry#names_and_taxonomy" } ] }, { "name": "mast cell protease 2", "type": "synonym", "evidence": [ { "id": "XP_002696732", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696732" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIP7", "url": "https://www.uniprot.org/uniprotkb/E1BIP7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC540321", "url": "https://www.uniprot.org/uniprotkb/E1BIP7", "locus": {} } ], "crossref": [ { "id": "E1BIP7", "url": "https://alphafold.ebi.ac.uk/entry/E1BIP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000052449", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000052449", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540321", "url": "https://www.ncbi.nlm.nih.gov/gene/540321", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540321", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540321", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWHGKLA", "url": "https://omabrowser.org/oma/group/TWHGKLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIP7", "url": "https://www.orthodb.org/?gene=E1BIP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002696732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696732", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BIP7", "url": "https://www.uniprot.org/uniprotkb/E1BIP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIP7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHHPPLPLLLLLLLCCRTQAGEIIGGTESKPHSRPYMAYLQIVTWHGKLAACGGFLIRRDFVLTAAHCAGRSITVILGAHNLQKKEDTWQRLEVIKQFPYPKYEHVGLHDIMLLKLKEKANLTLAVGTIPLPSHFTFIHPGIMCWVAGWGQTAVNEPASSILQEVELRLMEPRACSHFSAFNHNLQLCVGNPQSTKSTFKGDSGGPLLCAGVAQGIVSYGLSNAKPPAVFTRISPYRPWIDEVLKGN", "length": 247, "header": "tr|E1BIP7-1|E1BIP7_BOVIN Isoform 1 of Peptidase S1 domain-containing protein OS=Bos taurus OX=9913 GN=LOC540321 PE=4 SV=3 CANONICAL=E1BIP7-1" }, "isoforms": [ { "isoform_ac": "E1BIP7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIP7/entry#E1BIP7-1", "sequence": { "sequence": "MHHPPLPLLLLLLLCCRTQAGEIIGGTESKPHSRPYMAYLQIVTWHGKLAACGGFLIRRDFVLTAAHCAGRSITVILGAHNLQKKEDTWQRLEVIKQFPYPKYEHVGLHDIMLLKLKEKANLTLAVGTIPLPSHFTFIHPGIMCWVAGWGQTAVNEPASSILQEVELRLMEPRACSHFSAFNHNLQLCVGNPQSTKSTFKGDSGGPLLCAGVAQGIVSYGLSNAKPPAVFTRISPYRPWIDEVLKGN", "length": 247, "header": "tr|E1BIP7-1|E1BIP7_BOVIN Isoform 1 of Peptidase S1 domain-containing protein OS=Bos taurus OX=9913 GN=LOC540321 PE=4 SV=3 CANONICAL=E1BIP7-1" }, "locus": { "chromosome": "21", "start_pos": 34720487, "end_pos": 34717800, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011737.6", "url": "https://www.ensembl.org/id/ENSBTAT00000011737.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011737.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011737.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540321", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540321", "resource": 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"reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIP7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 247, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIP7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIP7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP7" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 245, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIS9-1", "uniprot_ac": "E1BIS9", "uniprot_id": "E1BIS9_BOVIN", "mass": { "chemical_mass": 35898.0, "monoisotopic_mass": 35898.0 }, "refseq": { "ac": "NP_001180009", "name": "sulfotransferase 1C3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180009" }, "gene_names": [ { "name": "SULT1C3", "type": "recommended", "evidence": [ { "id": "E1BIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ] }, { "name": "SULT1C3", "type": "synonym", "evidence": [ { "id": "NP_001180009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180009" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "E1BIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS9/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "E1BIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS9/entry#names_and_taxonomy" } ] }, { "name": "sulfotransferase 1C3", "type": "synonym", "evidence": [ { "id": "NP_001180009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180009" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIS9", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SULT1C3", "url": "https://www.uniprot.org/uniprotkb/E1BIS9", "locus": { "chromosome": "11", "start_pos": 44905838, "end_pos": 44925201, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002803", "url": "https://www.ensembl.org/id/ENSBTAG00000002803" } ] } } ], "crossref": [ { "id": "E1BIS9", "url": "https://alphafold.ebi.ac.uk/entry/E1BIS9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002803", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002803", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "615528", "url": "https://www.ncbi.nlm.nih.gov/gene/615528", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:615528", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615528", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQRANTY", "url": "https://omabrowser.org/oma/group/CQRANTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIS9", "url": "https://www.orthodb.org/?gene=E1BIS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11783", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11783", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180009", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180009", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "70607", "url": "https://www.rhea-db.org/rhea/70607", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BIS9", "url": "https://www.uniprot.org/uniprotkb/E1BIS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIS9-1", "url": "https://www.uniprot.org/uniprotkb/E1BIS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLEEMKDLHLEEKYLQPETKEVNGILMTKMISDNWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDLQKCQRANTFDRHPFIEWALPPPLSSGLDLANKMPSPRTLKTHLPVQMLPPSFWKENAKIIYVARNAKDCLVSYYHFSRMNKMVPDPGSWEEYVETFKAGKVLWGSWYDHVKGWWHAKDQHRILYLFYEDMKEDPRREIRKILKFLEKEVSEEVLDKIIHHTSFEVMKENPMANYTTLPTSIMDHSISPFMRRGMPGDWKNYFTVAQNEDFDKDYERKMAGSTLTFRTAL", "length": 304, "header": "tr|E1BIS9-1|E1BIS9_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=SULT1C3 PE=3 SV=1 CANONICAL=E1BIS9-1" }, "isoforms": [ { "isoform_ac": "E1BIS9-1", "url": "https://www.uniprot.org/uniprotkb/E1BIS9/entry#E1BIS9-1", "sequence": { "sequence": "MSLEEMKDLHLEEKYLQPETKEVNGILMTKMISDNWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDLQKCQRANTFDRHPFIEWALPPPLSSGLDLANKMPSPRTLKTHLPVQMLPPSFWKENAKIIYVARNAKDCLVSYYHFSRMNKMVPDPGSWEEYVETFKAGKVLWGSWYDHVKGWWHAKDQHRILYLFYEDMKEDPRREIRKILKFLEKEVSEEVLDKIIHHTSFEVMKENPMANYTTLPTSIMDHSISPFMRRGMPGDWKNYFTVAQNEDFDKDYERKMAGSTLTFRTAL", "length": 304, "header": "tr|E1BIS9-1|E1BIS9_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=SULT1C3 PE=3 SV=1 CANONICAL=E1BIS9-1" }, "locus": { "chromosome": "11", "start_pos": 44921512, "end_pos": 44906842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003630.4", "url": "https://www.ensembl.org/id/ENSBTAT00000003630.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003630.2", "url": "https://www.ensembl.org/id/ENSBTAP00000003630.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:615528", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615528", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IL54-1", "protein_name": "Sulfotransferase", "gene_name": "LOC100759957", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLEEIKSLHLEEQHLQPETKEVNGILMSKMMSDNWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTFDRHPFLEWTLPPPLNSGLDLANKMPSPRTLKTHLPVQMLPPSFWKENSKIIYVARNAKDCLVSYYHFSRMNKMLPDPGTWEEYVETFKAGKVLWGSWYDHVKGWWDVKDQHHILYLFYEDMKEDPKREIKKIVKFLEKDISEEVLNKVIYHTSFDVMKQNPMANYTTLPSSIMDHSISPFMRKGMPGDWKNYFTVAQSEDFDEDYRKKMAGSTITFRTEI", "length": 304 }, "evidence": [ { "id": "E1BIS9", "url": "https://omabrowser.org/oma/group/E1BIS9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3L648-1", "protein_name": "Sulfotransferase", "gene_name": "SULT1C3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSWEEMKDLQLEEKPLPLETKELNGILMTKMMSDNWDKIWNFQAKPDDLLIATYTKAGTTWTQEIVDMIHNDGDVQKCQRANTFDRHPFIEWTLPLPLNSGLDLAIKMPSPRTLKTHLPVQMVPPSFWKENVKIIYMARNAKDSLVSYYHFSRMNKMFPDPGPWEEYIEAFKAGKVLWGSWYDHVRGWWDAKDRHRILYLFYEDMKEDPKREIQKILKFLEKDISEEVLNKIIHHTSFDVMKQNPMANYTTIPTSMMDHSISPFMRKGVPGDWKNHFTVAQNKDFDEDYEKKMAGTTLTFRTTI", "length": 304 }, "evidence": [ { "id": "E1BIS9", "url": "https://omabrowser.org/oma/group/E1BIS9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P50237-1", "protein_name": "Sulfotransferase 1C1", "gene_name": "Sult1c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLEKMKDLHLGEQDLQPETREVNGILMSKLMSDNWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTYDRHPFIEWTLPSPLNSGLDLANKMPSPRTLKTHLPVHMLPPSFWKENSKIIYVARNAKDCLVSYYYFSRMNKMLPDPGTLGEYIEQFKAGKVLWGSWYDHVKGWWDVKDQHRILYLFYEDMKEDPKREIKKIAKFLEKDISEEVLNKIIYHTSFDVMKENPMANYTTLPSSIMDHSISPFMRKGMPGDWKNYFTVAQSEDFDEDYRRKMAGSNITFRTEI", "length": 304 }, "evidence": [ { "id": "E1BIS9", "url": "https://omabrowser.org/oma/group/E1BIS9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IMI6-1", "protein_name": "Sulfotransferase 1C3", "gene_name": "SULT1C3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKIEKNAPTMEKKPELFNIMEVDGVPTLILSKEWWEKVCNFQAKPDDLILATYPKSGTTWMHEILDMILNDGDVEKCKRAQTLDRHAFLELKFPHKEKPDLEFVLEMSSPQLIKTHLPSHLIPPSIWKENCKIVYVARNPKDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGGSWFDHVKGWWAAKDMHRILYLFYEDIKKDPKREIEKILKFLEKDISEEILNKIIYHTSFDVMKQNPMTNYTTLPTSIMDHSISPFMRKGMPGDWKNYFTVAQNEEFDKDYQKKMAGSTLTFRTEI", "length": 304 }, "evidence": [ { "id": "E1BIS9", "url": "https://omabrowser.org/oma/group/E1BIS9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80VR3-1", "protein_name": "Sulfotransferase 1C1", "gene_name": "Sult1c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLEKLKDLHLDEQNMQPETREVNGILMSKMMSENWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTYDRHPFIEWTLPPPLNSGLDLANKMPSPRTLKTHLPVQMLPPSFWKENSKIIYVARNAKDCLVSYYYFSRMNKMLPDPGTLGEYIETFKAGKVLWGSWYDHVKGWWDVKDKHRILYLFYEDMKEDPKREIKKIVKFLEKDISEEVLNKIIHHTSFDVMKQNPMANYTTLPSSIMDHSISPFMRKGMPGDWKNYFTVAQSEDFDEDYRKKMAGSTITFRTEI", "length": 304 }, "evidence": [ { "id": "E1BIS9", "url": "https://omabrowser.org/oma/group/E1BIS9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "3'-phosphoadenosine 5'-phosphosulfate binding", "id": "GO:0050656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050656", "evidence": [ { "database": "UniProtKB", "id": "E1BIS9", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ], "pmid": "" }, { "name": "alcohol sulfotransferase activity", "id": "GO:0004027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004027", "evidence": [ { "database": "UniProtKB", "id": "E1BIS9", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ], "pmid": "" }, { "name": "aryl sulfotransferase activity", "id": "GO:0004062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004062", "evidence": [ { "database": "UniProtKB", "id": "E1BIS9", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sulfation", "id": "GO:0051923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051923", "evidence": [ { "database": "UniProtKB", "id": "E1BIS9", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ], "pmid": "" }, { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "E1BIS9", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ], "pmid": "" }, { "name": "3'-phosphoadenosine 5'-phosphosulfate metabolic process", "id": "GO:0050427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050427", "evidence": [ { "database": "UniProtKB", "id": "E1BIS9", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BIS9", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70607", "name": "", "equation": "4-ethylphenol + 3'-phosphoadenylyl sulfate = 4-ethylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3T0Y3-1", "P50227-1", "P19217-1", "A0AAA9RW31-1", "A0A3Q1N4J6-1", "F1MZX9-1", "E1BG19-1", "E1BAC7-1", "E1BIS9-1", "A0ABI0NTS0-1", "A0AAA9SGU9-1", "A0ABI0P531-1", "E1BJ78-1" ], "evidence": [ { "id": "70607", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70607" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1N4J6", "gene_name": "", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1N4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4J6" } ] } ] }, { "uniprot_ac": "A0AAA9RW31", "gene_name": "LOC100300896", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0AAA9RW31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW31" } ] } ] }, { "uniprot_ac": "A0AAA9SGU9", "gene_name": "LOC514658", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0AAA9SGU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGU9" } ] } ] }, { "uniprot_ac": "A0ABI0NTS0", "gene_name": "SULT1C2", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0ABI0NTS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0" } ] } ] }, { "uniprot_ac": "A0ABI0P531", "gene_name": "LOC112446736", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0ABI0P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P531" } ] } ] }, { "uniprot_ac": "E1BAC7", "gene_name": "SULT1D1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BAC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAC7" } ] } ] }, { "uniprot_ac": "E1BG19", "gene_name": "SULT2A1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG19" } ] } ] }, { "uniprot_ac": "E1BIS9", "gene_name": "SULT1C3", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ] } ] }, { "uniprot_ac": "E1BJ78", "gene_name": "LOC783020", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BJ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ78" } ] } ] }, { "uniprot_ac": "F1MZX9", "gene_name": "SULT6B1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "F1MZX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZX9" } ] } ] }, { "uniprot_ac": "P19217", "gene_name": "SULT1E1", "activity": [ { "ec_number": "2.8.2.4", "activity": "estrone + 3'-phosphoadenylyl sulfate = estrone 3-sulfate + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "P19217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19217" } ] }, { "ec_number": "2.8.2.4", "activity": "", "evidence": [ { "id": "P19217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19217" } ] } ] }, { "uniprot_ac": "P50227", "gene_name": "SULT1A1", "activity": [ { "ec_number": "2.8.2.1", "activity": "a phenol + 3'-phosphoadenylyl sulfate = an aryl sulfate + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "P50227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50227" } ] }, { "ec_number": "2.8.2.1", "activity": "", "evidence": [ { "id": "P50227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50227" } ] } ] }, { "uniprot_ac": "Q3T0Y3", "gene_name": "SULT1B1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "Q3T0Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Y3" } ] }, { "ec_number": "2.8.2.1", "activity": "a phenol + 3'-phosphoadenylyl sulfate = an aryl sulfate + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "Q3T0Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Y3" } ] }, { "ec_number": "2.8.2.1", "activity": "", "evidence": [ { "id": "Q3T0Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Y3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIS9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 304, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIS9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIS9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 296, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 248, "end_pos": 250 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIU3-1", "uniprot_ac": "E1BIU3", "uniprot_id": "E1BIU3_BOVIN", "mass": { "chemical_mass": 21116.0, "monoisotopic_mass": 21116.0 }, "refseq": {}, "gene_names": [ { "name": "LOC112442552", "type": "recommended", "evidence": [ { "id": "E1BIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU3" } ] } ], "protein_names": [ { "name": "High mobility group protein B3", "type": "recommended", "evidence": [ { "id": "E1BIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference for non-canonical DNA structures such as single-stranded DNA. Can bend DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters. Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor. Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling.", "evidence": [ { "database": "UniProtKB", "id": "E1BIU3", "url": "https://www.uniprot.org/uniprotkb/E1BIU3#function" }, { "database": "UniProtKB", "id": "ARBA00055449", "url": "https://www.uniprot.org/uniprotkb/ARBA00055449#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIU3", "url": "https://www.uniprot.org/uniprotkb/E1BIU3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC112442552", "url": "https://www.uniprot.org/uniprotkb/E1BIU3", "locus": {} } ], "crossref": [ { "id": "E1BIU3", "url": "https://alphafold.ebi.ac.uk/entry/E1BIU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000031711", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000031711", "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48112:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48112:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09011", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09011", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BIU3", "url": "https://www.uniprot.org/uniprotkb/E1BIU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIU3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIV1", "url": "https://www.uniprot.org/uniprotkb/E1BIV1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FOXD3", "url": "https://www.uniprot.org/uniprotkb/E1BIV1", "locus": { "chromosome": "3", "start_pos": 82243730, "end_pos": 82245175, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008501", "url": "https://www.ensembl.org/id/ENSBTAG00000008501" } ] } } ], "crossref": [ { "id": "E1BIV1", "url": "https://alphafold.ebi.ac.uk/entry/E1BIV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008501", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008501", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20047", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20047", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532383", 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"url": "https://www.uniprot.org/uniprotkb/E1BIV1" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "E1BIV1", "url": "https://www.uniprot.org/uniprotkb/E1BIV1" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "E1BIV1", "url": "https://www.uniprot.org/uniprotkb/E1BIV1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BIV1", "url": "https://www.uniprot.org/uniprotkb/E1BIV1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": 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"url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIV1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIV1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIV1" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 235, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 227, "end_pos": 229 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIX3-1", "uniprot_ac": "E1BIX3", "uniprot_id": "E1BIX3_BOVIN", "mass": { "chemical_mass": 92557.0, "monoisotopic_mass": 92557.0 }, "refseq": {}, "gene_names": [ { "name": "CAPN7", "type": "recommended", "evidence": [ { "id": "E1BIX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIX3" } ] } ], "protein_names": [ { "name": "Calpain-7", "type": "recommended", "evidence": [ { "id": "E1BIX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIX3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Calcium-regulated non-lysosomal thiol-protease.", "evidence": [ { "database": "UniProtKB", "id": "E1BIX3", "url": "https://www.uniprot.org/uniprotkb/E1BIX3#function" }, { "database": "UniProtKB", "id": "ARBA00002989", "url": "https://www.uniprot.org/uniprotkb/ARBA00002989#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIX3", "url": "https://www.uniprot.org/uniprotkb/E1BIX3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CAPN7", "url": "https://www.uniprot.org/uniprotkb/E1BIX3", "locus": { "chromosome": "1", "start_pos": 152284372, "end_pos": 152232456, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006479", "url": "https://www.ensembl.org/id/ENSBTAG00000006479" } ] } } ], "crossref": [ { "id": "E1BIX3", "url": "https://alphafold.ebi.ac.uk/entry/E1BIX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006479", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006479", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02681", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02681", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GDYRRGC", "url": "https://omabrowser.org/oma/group/GDYRRGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIX3", "url": "https://www.orthodb.org/?gene=E1BIX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46143:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46143:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1474228", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1474228", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BIX3", "url": "https://www.uniprot.org/uniprotkb/E1BIX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIX3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSAALERDAVQFARLAVQRDQEGRYAEAVFYYKEAAQALIYAEMAGSSLEHIQEKINEYLERVQALHSAVQSKSADPLKSKHQLDLERAHFLVTQAFDEDEKGNVEDAIELYTEAVDLCLKTSYETADKTLQNKLKQLARQALDRAEALSEPLTKQSCKIKATNTKPKPPPTRTHFPLGTNPFLERPQPFISPQSCDAQGQRYTAEEIEVLRTTSKINGIEYVPFMSIDLRERFAYPMPFCDRCGKLPLSPKQKATFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRFNKKLITSIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQAFSKDNSFRMLYQRFHKGDVLITASTGVMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWISWDDLCQYYDVIYLSWNPGLFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFANNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYEKQNTIHYTVRVYSACSFTFSKIPSPYTVSKQINGKWSGQSAGGCGNFQETHKNNPIYQFHIEKTGPLLIELRGPRQYSVGFEVVTVSVVGDPGPHGFQRKSSGDYRCGFCYLELENIPAGIYNIIPSTFLPKQEGPFFLDFNSIIPIKTTQLQ", "length": 813, "header": "tr|E1BIX3-1|E1BIX3_BOVIN Isoform 1 of Calpain-7 OS=Bos taurus OX=9913 GN=CAPN7 PE=3 SV=2 CANONICAL=E1BIX3-1" }, "isoforms": [ { "isoform_ac": "E1BIX3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIX3/entry#E1BIX3-1", "sequence": { "sequence": "MDSAALERDAVQFARLAVQRDQEGRYAEAVFYYKEAAQALIYAEMAGSSLEHIQEKINEYLERVQALHSAVQSKSADPLKSKHQLDLERAHFLVTQAFDEDEKGNVEDAIELYTEAVDLCLKTSYETADKTLQNKLKQLARQALDRAEALSEPLTKQSCKIKATNTKPKPPPTRTHFPLGTNPFLERPQPFISPQSCDAQGQRYTAEEIEVLRTTSKINGIEYVPFMSIDLRERFAYPMPFCDRCGKLPLSPKQKATFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRFNKKLITSIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQAFSKDNSFRMLYQRFHKGDVLITASTGVMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWISWDDLCQYYDVIYLSWNPGLFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFANNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYEKQNTIHYTVRVYSACSFTFSKIPSPYTVSKQINGKWSGQSAGGCGNFQETHKNNPIYQFHIEKTGPLLIELRGPRQYSVGFEVVTVSVVGDPGPHGFQRKSSGDYRCGFCYLELENIPAGIYNIIPSTFLPKQEGPFFLDFNSIIPIKTTQLQ", "length": 813, "header": "tr|E1BIX3-1|E1BIX3_BOVIN Isoform 1 of Calpain-7 OS=Bos taurus OX=9913 GN=CAPN7 PE=3 SV=2 CANONICAL=E1BIX3-1" }, "locus": { "chromosome": "1", "start_pos": 152283296, "end_pos": 152232655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008495.8", "url": "https://www.ensembl.org/id/ENSBTAT00000008495.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008495.5", "url": "https://www.ensembl.org/id/ENSBTAP00000008495.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1474228", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1474228", "resource": "Reactome", "description": "Degradation of the extracellular matrix" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MLZ4-1", "protein_name": "Calpain-7", "gene_name": "Capn7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDATALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLERIQEKISEYLERVQALHSAVQSKSADPLKSKHQLDLERAHFLVTQAFDEDEKGNVEDAIELYTEAVDLCLKTSYETADKTLQNKLKQLARQALDRAEALSEPLTKPFCKLKSTNMKTKTPPVRTHFPLGPNPFLEKPQPFISPQSCDAQGQRYTAEEIEVLRTTSKINGIEYVPFMSVDLRERFAYPMPFCDRWGKLPLSPKQKTTFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRFNKKLITSIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQTFSKDNSFRMLYQRFHKGDVLITASTGMMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWISWDDLCQYYDVVYLSWNPALFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFANNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYEKQNTIHYTVRVYSACSFTFSKIPSPYTLSKRINGKWSGQSAGGCGNFQETHKNNPIYQFHVDKTGPLLIELRGPRQYSVGFEVVAVSIIGDSGPHCFQRKSSGDYRCGFCYLELENIPAGIFNIIPSTFLPKQEGPFFLDFNSTVPIKTTQLQ", "length": 813 }, "evidence": [ { "id": "E1BIX3", "url": "https://omabrowser.org/oma/group/E1BIX3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0Z0N6-1", "protein_name": "Calpain 7", "gene_name": "CAPN7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDASALELDAVKFAQLAVQRDQSGRYQEAVFYYKEAAQALIYAGMAGSSLENIQEKINEYLERVQALHSAVQSQNTDPLKSKQQLDLERAHFLVTQAFDEDDKGNAEEAIELYTEAVELCLKTATETSEAGLQSKLKQLARQALDRAEALKVSMSKSSQKEKSTAAKPNQPVRTFFPLGPDFSLNDKPQTIRAVQASESQGQRYTAEEIEVLRKTSKINGIEYVPFMSVDLRERFAFPMPFSDKCGKLPLSPKQKAMFAKWVRPDDITNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRYNKKLITSIIYPQNKKGEPEYNPCGKYMVKLHINGVPRKVIIDDQLPVDHSGELLCSYSNNKNELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDNQAFDRDSTFRMLYQRFHKGDVLITTATGVMSEEEGEKWGLVPTHAYAVLDIREHKGLRFLQLKNPWSHLRWKGRYSENDTRSWTPDLQKYLNFDPRTAQKIDNGIFWIAWEDLCQYYDVIYLSWNPGLFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAVVWVLLSRHITDKDDFAHNREFITMVVYKTDGKKVYYPADPVPYIDGIRINSPHYLTKIKLTSPGTHTFTLVVSQYEKQNTIHYTIRVYSLCKFTFSKIPTPYTISKRVNGQWKGHSAGGCGNFRDSYKNNPIYQFQLDKSGPLLIELRGPRQYSVGFEIVTVSTVGDPGSYGFQKKSSGDYRCGFCYLEVENILAGVYNIIPTTFLPQQEGPFFLDFNSTSPLRVSQLQ", "length": 813 }, "evidence": [ { "id": "E1BIX3", "url": "https://omabrowser.org/oma/group/E1BIX3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LBF0-1", "protein_name": "Calpain-7", "gene_name": "CAPN7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDAAALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLEHIQEKINEYLERVQALHSAVQSKSADPLKSKHQLDLERAHFLVTQAFDEDEKGNVEDAIELYTEAVDLCLKTSYETADKTLQNKLKQLARQALDRAEALSEPLTKPLCKVKATNIKPKPPPTRTHFPLGTNPFQERPQPFISPQSCDAQGQRYTAEEIEVLRTTSKINGIEYVPFMNIDLRERFAYPMPFCDRCGKLPLSPKQKAMFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRFNKKLITSIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQSFSKDNSFRMLYQRFHKGDVLITASTGVMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWISWDDLCQYYDVIYLSWNPGLFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFANNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYEKQNTIHYTVRVYSACSFTFSKIPSPYTVSKQINGKWSGQSAGGCGNFQETHKNNPIYQFHIEKSGPLLIELRGPRQYSVGFEVVTVSVVGDPGPHGFQRKSSGDYRCGFCYLELESIPAGIYNIIPSTFLPKQEGPFFLDFNSVIPIKTTQLQ", "length": 813 }, "evidence": [ { "id": "E1BIX3", "url": "https://omabrowser.org/oma/group/E1BIX3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9R1S8-1", "protein_name": "Calpain-7", "gene_name": "Capn7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDASALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLERIQEKINEYLERVQALHSAVQSKSTDPLKSKHQLDLERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETADKTLQNKLKQLARQALDRAEALSEPLTKPFCKLKSANMKTKTPPVRTHFPLGPNPFVEKPQAFISPQSCDAQGQKYTAEEIEVLRTTSKINGVEYVPFMSVDLRERFAYPMPFCDRLGKLPLSPKQKTTFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRFNKKLITSIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQTFSKDNSFRMLYQRFHKGDVLITASTGVMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWISWDDLCQYYDVVYLSWNPALFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFANNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYEKQNTIHYTVRVYSACSFTFSKIPSPYTLSKRINGKWSGQSAGGCGNFQETHKNNPIYQFHIDKTGPLLIELRGPRQYSVGFEVVAVSIMGDPGPHGFQRKSSGDYRCGFCYLELENIPAGIFNIIPSTFLPKQEGPFFLDFNSTVPIKTTQLQ", "length": 813 }, "evidence": [ { "id": "E1BIX3", "url": "https://omabrowser.org/oma/group/E1BIX3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6W3-1", "protein_name": "Calpain-7", "gene_name": "CAPN7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDATALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLENIQEKITEYLERVQALHSAVQSKSADPLKSKHQLDLERAHFLVTQAFDEDEKENVEDAIELYTEAVDLCLKTSYETADKVLQNKLKQLARQALDRAEALSEPLTKPVGKISSTSVKPKPPPVRAHFPLGANPFLERPQSFISPQSCDAQGQRYTAEEIEVLRTTSKINGIEYVPFMNVDLRERFAYPMPFCDRWGKLPLSPKQKTTFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRFNKKLITGIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQTFSKDNSFRMLYQRFHKGDVLITASTGMMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWISWDDLCQYYDVIYLSWNPGLFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFANNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYEKQNTIHYTVRVYSACSFTFSKIPSPYTLSKRINGKWSGQSAGGCGNFQETHKNNPIYQFHIEKTGPLLIELRGPRQYSVGFEVVTVSTLGDPGPHGFLRKSSGDYRCGFCYLELENIPSGIFNIIPSTFLPKQEGPFFLDFNSIIPIKITQLQ", "length": 813 }, "evidence": [ { "id": "E1BIX3", "url": "https://omabrowser.org/oma/group/E1BIX3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium-dependent cysteine-type endopeptidase activity", "id": "GO:0004198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004198", "evidence": [ { "database": "UniProtKB", "id": "E1BIX3", "url": "https://www.uniprot.org/uniprotkb/E1BIX3" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "E1BIX3", "url": "https://www.uniprot.org/uniprotkb/E1BIX3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BIX3", "url": "https://www.uniprot.org/uniprotkb/E1BIX3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BIX3", "url": "https://www.uniprot.org/uniprotkb/E1BIX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIX3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 813, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIX3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIX3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIX3" }, { "id": "PS50203", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calpain catalytic", "eco_id": "ECO_0000259", "start_pos": 260, "end_pos": 540, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 366, "end_pos": 368 }, { "start_pos": 496, "end_pos": 498 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIY2-1", "uniprot_ac": "E1BIY2", "uniprot_id": "E1BIY2_BOVIN", "mass": { "chemical_mass": 104795.0, "monoisotopic_mass": 104795.0 }, "refseq": { "ac": "NP_001192863", "name": "ADAMTS-like protein 2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192863" }, "gene_names": [ { "name": "ADAMTSL2", "type": "recommended", "evidence": [ { "id": "E1BIY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIY2" } ] }, { "name": "ADAMTSL2", "type": "synonym", "evidence": [ { "id": "NP_001192863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192863" } ] } ], "protein_names": [ { "name": "ADAMTS like 2", "type": "synonym", "evidence": [ { "id": "E1BIY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIY2/entry#names_and_taxonomy" } ] }, { "name": "ADAMTS-like protein 2 precursor", "type": "synonym", "evidence": [ { "id": "NP_001192863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192863" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIY2", "url": "https://www.uniprot.org/uniprotkb/E1BIY2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADAMTSL2", "url": "https://www.uniprot.org/uniprotkb/E1BIY2", "locus": { "chromosome": "11", "start_pos": 104449648, "end_pos": 104416289, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007492", "url": "https://www.ensembl.org/id/ENSBTAG00000007492" } ] } } ], "crossref": [ { "id": "E1BIY2", "url": "https://alphafold.ebi.ac.uk/entry/E1BIY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007492", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007492", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "526780", "url": "https://www.ncbi.nlm.nih.gov/gene/526780", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:526780", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526780", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RETNEVC", "url": "https://omabrowser.org/oma/group/RETNEVC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIY2", "url": "https://www.orthodb.org/?gene=E1BIY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192863", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192863", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BIY2", "url": "https://www.uniprot.org/uniprotkb/E1BIY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIY2-1", "url": "https://www.uniprot.org/uniprotkb/E1BIY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGRWQSSRWAWPLLAVALVTGSVSSTGTTDNSPTSNSLEVGPDATAYWWGEWTKWTACSRSCGAGVTSQERHCLQQRKTSVTGAGNRTCTGTSKRYQLCRVQECPPDGRSFREEQCISFNSRVYNGRRHQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPARDGTSCKLADLRGVCVSGKCEPIGCDGVLFSTHTLDKCGVCQGDGSSCTHVTGNYRKGNTHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYFFFNGNFKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHTHRLQPIYYSFSDPTSDSAESQELDGAGLAGFLQHNASLFGQASSERLGLDNRLFGHRGPGIELGLSRGQESNEVCAQASGRACEGPPRGKGFRDGNATLTALVGDPDDREADARFASQELLSANAISDQLLGAGSDSRELSLNETVNSIFSQGAPRGSPAESLYLDYEESEGAGAYLLNGSYLELSSDRLANTSSEAPFPNASASLPALAGNRTQKARTRPKSRKQGVSPADMYRWKLSSHEPCSSTCTTGVLSTYAMCVRYDGIEVDDSYCDALTRPEPVQEFCAGRECQPRWETSSWSECSRTCGEGYQFRIVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKTCRGPACGPQWEMSQWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGEKDCTGPPCDRQWTVSDWGPCSGSCGQGRMIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNCPAHWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPPDDSCQDQPGTNCALAIKVNLCGHWYYSKACCHSCRPPPS", "length": 955, "header": "tr|E1BIY2-1|E1BIY2_BOVIN Isoform 1 of ADAMTS like 2 OS=Bos taurus OX=9913 GN=ADAMTSL2 PE=4 SV=3 CANONICAL=E1BIY2-1" }, "isoforms": [ { "isoform_ac": "E1BIY2-1", "url": "https://www.uniprot.org/uniprotkb/E1BIY2/entry#E1BIY2-1", "sequence": { "sequence": "MEGRWQSSRWAWPLLAVALVTGSVSSTGTTDNSPTSNSLEVGPDATAYWWGEWTKWTACSRSCGAGVTSQERHCLQQRKTSVTGAGNRTCTGTSKRYQLCRVQECPPDGRSFREEQCISFNSRVYNGRRHQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPARDGTSCKLADLRGVCVSGKCEPIGCDGVLFSTHTLDKCGVCQGDGSSCTHVTGNYRKGNTHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYFFFNGNFKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHTHRLQPIYYSFSDPTSDSAESQELDGAGLAGFLQHNASLFGQASSERLGLDNRLFGHRGPGIELGLSRGQESNEVCAQASGRACEGPPRGKGFRDGNATLTALVGDPDDREADARFASQELLSANAISDQLLGAGSDSRELSLNETVNSIFSQGAPRGSPAESLYLDYEESEGAGAYLLNGSYLELSSDRLANTSSEAPFPNASASLPALAGNRTQKARTRPKSRKQGVSPADMYRWKLSSHEPCSSTCTTGVLSTYAMCVRYDGIEVDDSYCDALTRPEPVQEFCAGRECQPRWETSSWSECSRTCGEGYQFRIVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKTCRGPACGPQWEMSQWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGEKDCTGPPCDRQWTVSDWGPCSGSCGQGRMIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNCPAHWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPPDDSCQDQPGTNCALAIKVNLCGHWYYSKACCHSCRPPPS", "length": 955, "header": "tr|E1BIY2-1|E1BIY2_BOVIN Isoform 1 of ADAMTS like 2 OS=Bos taurus OX=9913 GN=ADAMTSL2 PE=4 SV=3 CANONICAL=E1BIY2-1" }, "locus": { "chromosome": "11", "start_pos": 104449170, "end_pos": 104418528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009855.8", "url": "https://www.ensembl.org/id/ENSBTAT00000009855.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009855.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009855.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 913, "start_aa": "Thr", "end_pos": 913, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr913", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:526780", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526780", "resource": "KEGG Pathway" }, { "id": "R-BTA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A4X6-1", "protein_name": "ADAMTS-like protein 2", "gene_name": "Adamtsl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSGWQRSRWAWSLLAMAVVAGGAASTEASDNSPTSNSLEGGADATAYWWGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGAGNRTCVGTSKRYQLCRVQECPPDGRSFREEQCVSFNSRVYDGRAYQWKPLYPDDYMHISSKPCDLHCTTVDGQRQLMVPARDGTSCKLTDLRGVCVSGKCEVPIGCDGVLFSTHTLDKCGVCQGDGSSCTHVTGNYRKGDNHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGFYFFNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQSPHMHHLPPVYYSFSEAASESTESTERQELDSARLLGFLQHNGSLYGQPSSERLGLNSQLFPPTAPEVELGPSRGQETNEVCKQASGGVCEGPPRGKGFQDHNATGRALLGDKDDREISAHFTSHELLSANTISDQLLGTGSDSEEFSLNETMNSIFAQGAPRSSPAESLYVDYEENEGPAAYLINGSYLELNSDRINTSSEAPFPNTSASLPSLAGNRTHKARTRPKARKQGVSPADMYRWKLSSQEPCSATCTTGVMSAYAMCVRYDGVEVDDSYCDALTRPEPVHEFCAGRECQPRWETSSWSECSRTCGEGHQFRIVRCWKMLSPGFDSSVYSDLCEATEAVRPEERKTCRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDERLCDPNTRPVGEKNCTGPPCDRQWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQTETKPLAIHPCGDKNCPAHWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQMRSGSECGLARKPPEESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPPDDSCQDQPGTNCALAIKVNLCGHWYYSKACCRSCRPPHS", "length": 958 }, "evidence": [ { "id": "E1BIY2", "url": "https://omabrowser.org/oma/group/E1BIY2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LC14-1", "protein_name": "ADAMTS like 2", "gene_name": "ADAMTSL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGRWQPSRWAWSLLTMALVAGGASSTGATDNSPTSNSLEAGADATASWWGEWTKWTACSRSCGAGVTSQERHCLQQRRTSVTGAGNRTCTGTSKRYQLCRVQECPADGRSFREEQCISFNSRVYNGRTHQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPAHDGTSCKLADLRGVCVSGKCEPIGCDGVLFSTHTLDKCGVCQGDGSSCTHVTGNYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYFFFNGNFKVDSPKNFNIAGTVVKYRRPMDVFETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHAHRLQPLYYSFSEPVAQSAESVDSAELDGAGLLGFLRHNGSLYGQASSERLGLDNRLFGRRGPGIELGLSKGQETNEVCVQASGRACEGPPRGKGFRDSNTTGTALEGDQRDPEADARFASQERLSANAISDQLLGTGSDSKELAPNETVNSIFAQGGPRSSPAESLYVDYEENEGAGTYLLNGSYLQLSSDRVTNTSAEAPFPNASASLPALGGNRTQKARTRPKARKPGVSPADMYRWKLSSHEPCSATCTTGVMSTYAMCVRYDGIEVDDSYCDALTRPEPVQEFCAGRECQPRWETSSWSECSRTCGEGYQFRIVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKTCRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGEKDCTGPPCDRQWTVSDWGPCSGSCGQGRMIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNCPAHWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPAEESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPPDDSCQDQPGTNCALAIKVNLCGHWYYSKACCRSCRPPHS", "length": 958 }, "evidence": [ { "id": "E1BIY2", "url": "https://omabrowser.org/oma/group/E1BIY2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7TSK7-1", "protein_name": "ADAMTS-like protein 2", "gene_name": "Adamtsl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGRRQHPHWAWSLLAVAVVAGGAAPTEASDNSPTSNSLEGGADTTAYWWGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGTGNRTCVGTSKRYQLCRVQECPPDGRSFREEQCVSFNSRVYDGRAYQWKPLYPDDYVHISSKPCDLHCSTVDGQRQLTVPARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGVCQGDGSSCTHVTGNYRKGNNHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGFYFFNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQSPHMHHLPPVYYSFSEAASQSTESTERQELDSARLLGFMQHNGSLYRQTSSERLGLNSQLFQPPAPEVELGPSRGQESNEVCKQASGGVCEGPPRGKGFQDHNATGRAFSADKDDREISAHFTSHELLSANTISDQLLGTGSESEEFSLNETMNSIFAQGAPRSSPAESLYVDYEENEGPAAYLINGSYLELSSDRINTSSEAPFPNTSASPPNLAGNRTHKARTRPKARKQGVSPADMYRWKLSSHEPCSATCTTGVMSTYAMCVRYDGVEVDDSYCDALTRPEPVHEFCAGRECQPRWETSSWSECSRTCGEGHQFRIVRCWKMLSPGFDSSVYSDLCEATEAVRPEERKTCRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPSTKPVGEKNCTGPPCDRQWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQTETKPLAIHPCGDKNCPAHWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQIRSGPECGLARKPPEESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPPDDSCQDQPGTNCALAIKVNLCGHWYYSKACCRSCRPPHS", "length": 957 }, "evidence": [ { "id": "E1BIY2", "url": "https://omabrowser.org/oma/group/E1BIY2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86TH1-1", "protein_name": "ADAMTS-like protein 2", "gene_name": "ADAMTSL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGRWQCSCWAWFLLVLAVVAGDTVSTGSTDNSPTSNSLEGGTDATAFWWGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDGRSFREEQCVSFNSHVYNGRTHQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYYFFNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHESRPQPIYYGFSESAESQGLDGAGLMGFVPHNGSLYGQASSERLGLDNRLFGHPGLDMELGPSQGQETNEVCEQAGGGACEGPPRGKGFRDRNVTGTPLTGDKDDEEVDTHFASQEFFSANAISDQLLGAGSDLKDFTLNETVNSIFAQGAPRSSLAESFFVDYEENEGAGPYLLNGSYLELSSDRVANSSSEAPFPNVSTSLLTSAGNRTHKARTRPKARKQGVSPADMYRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEVDDSYCDALTRPEPVHEFCAGRECQPRWETSSWSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKTCRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGEKNCTGPPCDRQWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNCPAHWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPPDDSCQDQPGTNCALAIKVNLCGHWYYSKACCRSCRPPHS", "length": 951 }, "evidence": [ { "id": "E1BIY2", "url": "https://omabrowser.org/oma/group/E1BIY2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BIY2", "url": "https://www.uniprot.org/uniprotkb/E1BIY2" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "E1BIY2", "url": "https://www.uniprot.org/uniprotkb/E1BIY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "E1BIY2", "url": "https://www.uniprot.org/uniprotkb/E1BIY2" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "E1BIY2", "url": "https://www.uniprot.org/uniprotkb/E1BIY2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microfibril binding", "id": "GO:0050436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050436", "evidence": [ { "database": "UniProtKB", "id": "E1BIY2", "url": "https://www.uniprot.org/uniprotkb/E1BIY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 811, "end_pos": 813, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIY2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 955, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIY2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIY2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIY2" }, { "id": "PS50900", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50900" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLAC", "eco_id": "ECO_0000259", "start_pos": 916, "end_pos": 954, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 913 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 371, "end_pos": 373 }, { "start_pos": 432, "end_pos": 434 }, { "start_pos": 479, "end_pos": 481 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 528, "end_pos": 530 }, { "start_pos": 537, "end_pos": 539 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 811, "end_pos": 813 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BIZ7-1", "uniprot_ac": "E1BIZ7", "uniprot_id": "E1BIZ7_BOVIN", "mass": { "chemical_mass": 102761.0, "monoisotopic_mass": 102761.0 }, "refseq": { "ac": "XP_024833262", "name": "MLX-interacting protein isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833262" }, "gene_names": [ { "name": "MLXIP", "type": "recommended", "evidence": [ { "id": "E1BIZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7" } ] }, { "name": "MLXIP", "type": "synonym", "evidence": [ { "id": "XP_024833262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833262" } ] } ], "protein_names": [ { "name": "MLX interacting protein", "type": "synonym", "evidence": [ { "id": "E1BIZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7/entry#names_and_taxonomy" } ] }, { "name": "MLX-interacting protein isoform X3", "type": "synonym", "evidence": [ { "id": "XP_024833262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833262" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIZ7", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MLXIP", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7", "locus": { "chromosome": "17", "start_pos": 53223799, "end_pos": 53284518, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004189", "url": "https://www.ensembl.org/id/ENSBTAG00000004189" } ] } } ], "crossref": [ { "id": "E1BIZ7", "url": "https://alphafold.ebi.ac.uk/entry/E1BIZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004189", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004189", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19688", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19688", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21772", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21772", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "783217", "url": "https://www.ncbi.nlm.nih.gov/gene/783217", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TEFHSSI", "url": "https://omabrowser.org/oma/group/TEFHSSI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIZ7", "url": "https://www.orthodb.org/?gene=E1BIZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15741", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15741", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15741:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15741:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024833262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833262", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BIZ7", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIZ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADVFMCSQSRPRSRGRAVLLKPQVPEDDDDSDTDEPSPPPASGAATPARGQASAVLPPPKAGSGREEPPRRQQIIHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVEVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDEDLSSLAQDDDMLYWHKHRDGWKTPVPMEEDTLLDTDMLMSEFSDTLFSTLSSHPPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPAPASTPAPDPNSPPAQESILPTTALPTDLPTASLPDSFIAPPAAAALDPTSGQGCEHPPQPGDPFMQPADLGPSAPPLSGPQPYLPVFTLPLLSPSPAPPPPSPVLPLGPPPATALNPPTPPTFLQPQKFAEAGKSPSVITHTASATLTHDASATTFSQSQGLIITTRYPPPSGSPYGLALSPVTRPPTVGPPQPRLTFVHPKPVSLPGGRHKQPPKIVPAPKPEPVSVVLKNACLTPAAAFPGQPQAVIMTSGPLKREGMLASTVSQSNVVLTPAALTRAPGVAEFPSSILVTDLGPGPGSQHAPVSRLFPPDSLVKGEQGPLHGGIAQVPATGAGDSALRLDRLGPRRDCPNSGQASPCASEQSPSPQSPQNNCSGKSPADPKNVAVLKNRQMKHISAEQKRRFNIKMGFDTLNSLISNNTKLTSHAITLQKTVEYITKLQQERSQMQEEARRLREEIEELNATILSCQQLLPATGVPVTRRQFDHMRDMFDEYVKSRTLQNWKFWIFSVIIKPLFESFKGVVSTSSLDELHRTALSWLDEHCSLPILRPTVLNTLRHLSTTTSILTDPSQLPEQAAEAVSRISQRAGES", "length": 940, "header": "tr|E1BIZ7-1|E1BIZ7_BOVIN Isoform 1 of MLX interacting protein OS=Bos taurus OX=9913 GN=MLXIP PE=4 SV=3 CANONICAL=E1BIZ7-1" }, "isoforms": [ { "isoform_ac": "E1BIZ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7/entry#E1BIZ7-1", "sequence": { "sequence": "MAADVFMCSQSRPRSRGRAVLLKPQVPEDDDDSDTDEPSPPPASGAATPARGQASAVLPPPKAGSGREEPPRRQQIIHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVEVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDEDLSSLAQDDDMLYWHKHRDGWKTPVPMEEDTLLDTDMLMSEFSDTLFSTLSSHPPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPAPASTPAPDPNSPPAQESILPTTALPTDLPTASLPDSFIAPPAAAALDPTSGQGCEHPPQPGDPFMQPADLGPSAPPLSGPQPYLPVFTLPLLSPSPAPPPPSPVLPLGPPPATALNPPTPPTFLQPQKFAEAGKSPSVITHTASATLTHDASATTFSQSQGLIITTRYPPPSGSPYGLALSPVTRPPTVGPPQPRLTFVHPKPVSLPGGRHKQPPKIVPAPKPEPVSVVLKNACLTPAAAFPGQPQAVIMTSGPLKREGMLASTVSQSNVVLTPAALTRAPGVAEFPSSILVTDLGPGPGSQHAPVSRLFPPDSLVKGEQGPLHGGIAQVPATGAGDSALRLDRLGPRRDCPNSGQASPCASEQSPSPQSPQNNCSGKSPADPKNVAVLKNRQMKHISAEQKRRFNIKMGFDTLNSLISNNTKLTSHAITLQKTVEYITKLQQERSQMQEEARRLREEIEELNATILSCQQLLPATGVPVTRRQFDHMRDMFDEYVKSRTLQNWKFWIFSVIIKPLFESFKGVVSTSSLDELHRTALSWLDEHCSLPILRPTVLNTLRHLSTTTSILTDPSQLPEQAAEAVSRISQRAGES", "length": 940, "header": "tr|E1BIZ7-1|E1BIZ7_BOVIN Isoform 1 of MLX interacting protein OS=Bos taurus OX=9913 GN=MLXIP PE=4 SV=3 CANONICAL=E1BIZ7-1" }, "locus": { "chromosome": "17", "start_pos": 53284407, "end_pos": 53228373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005486.7", "url": "https://www.ensembl.org/id/ENSBTAT00000005486.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005486.6", "url": "https://www.ensembl.org/id/ENSBTAP00000005486.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 353, "start_aa": "Thr", "end_pos": 353, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr353", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 48, "start_aa": "Thr", "end_pos": 48, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr48", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A480YSZ7-1", "protein_name": "MLX interacting protein", "gene_name": "MLXIP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAEVFLCSPRRPHSRGRAVLLKPQVPEDDDDSDTDEPSPPPASGAATLARGHASAGPPQPRAGSGREEPPRRQQIIHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVEVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDEDLSSLAQDDDMLYWHKHGDGWKTPVPMEEDTLLDTDMLMSEFSDTLFSTLSSHPPVAWPNPREIAHLGNADMIQPGLMPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPAPASAAAPDPNSPPAQESILPTTALPTSSLPDSFIAPPVVTALDPTNGQGCEHTSQPGDPFVQPAELGPSAPPLTVPQSFLPVFTMPLLSPSPAPAPVSPALHLGPPPATALSPPTPPAFLQPQKFAEVSKSPSVITHTASATLTHDASATTFSQSQGLIITTRYPTPSMSACGLALSPVTRPMTVGPPQPRLTFVHPKPVSLPGVRHKQPPKIVPAPKPEPVSLVLKNARIAPAAFSGPPQAVIMTSGPLKREGMLASTVSQSNMVITPAAITRAPGVTEFHSSILVTDLGHSTGSQPAPVSRLFSPSTVPDSLVKGEQAPLHGGAPSVPATGPSRDCPNSGQASPCASEQSPSPQSPQNNCSGKSTADLKNVAALKNRQMKHISAEQKRRFNIKMGFDTLNSLISNNTKLTSHAITLQKTVEYITKLQQERSQMQEEARRLREEIEELNATILSCQQLLPATGVPVTRRQFDHMRDMFDEYVKSRTLQNWKFWIFSVIIKPLFESFKGVVSTSSLEELHRTALSWLDEHCSLPVLRPTVLNTLRHLSTTTSILTNPSQLPEQAAEAVTRIGKRPGES", "length": 927 }, "evidence": [ { "id": "E1BIZ7", "url": "https://omabrowser.org/oma/group/E1BIZ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZXJ9-1", "protein_name": "MLX interacting protein", "gene_name": "MLXIP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAADVFMRPAQLLGAAGPLSPRTEPDEDSSDTDDGGASPGGGRRCGPRRGQPPGPQIIHSGHFMVSSPHSEHPPKKGYDFDTVNEQTCQTYQFGAARGGGGAGGRLSIDASLTKLFECMSLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVDEHRRPEAIATEGKYWKRRIEIVIREYHKWRTYFKKRLQKHKDEDLSSLVRDDDVVLWQKRRYGRETPVPMEEGSLLDADMLMSEFTDTLFSTLSSHQLVSWPNPREIAHLGNADMIQPGLIPLQPNFDFMDTFEPFQDLFTPSRSSAYFPSVSAVSSATTDSSSHSSQSPVLPTGSLPNTLPSGNISDGLIASSVPSPVIPDVGTDQCSSIRSGGSFIQPADFAPDSSLSGPQTFLPVFQTPLPLLQPAAQQHQSPLPAVPLNTSLSSPPSAFAAPETQKFGLCESTVITHTASATLTHNAPATTFSQSQNLVLATQQPGAGVPCNLAFQTTVLQGQPRPQLQSQLTFALPKAVPLASAGTRPKQSQKIASAPKPETVSLLLKNAFITPAAFQGQSRAVIVTPTPLKREGILTPAMPQSNVKIAPAGIARAPGVTEFRSNILVGPAQQAPSSQQSQSTVSHLFSTNVVQDVLVKGEQVPSHNSSSQVPSPTPSRDCQNSGQASPCTSEQSPSPQSPQNSCSGKLATDSQMAALKTQRMKRTSSEQKRRFNIRIGCSILNSLVSVNSKLISHAITLQKTVEYIAKLQQERTQMQEETRRLREEIEELNAAIISCQQRLPATGVPVTWQRFDHIRSMFDEYVRNNTLQNWKFWIFSIIIKPLFESFNGMVSTASFKDLNQTAIAWLDQHCSLPVLRPMVLSSLRQLSVSTSVLSDPSRLPEQATEAVSRTNETAGET", "length": 917 }, "evidence": [ { "id": "E1BIZ7", "url": "https://omabrowser.org/oma/group/E1BIZ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1M051-1", "protein_name": "MLX interacting protein", "gene_name": "Mlxip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAADVFMCSPRRPRSRGRSVLLKPQVPEDDDDSDTDEPSPPPPSGVATSARAHASAAPLPPRAGPGREEPPRRQQIIHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDEDLSSLAQDDDMLYWHKHGDGWKTPVPMEEDSLLDTDMLMSEFSDTLFSTLSSHQPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQELFSSSRSIFGSMLPPPTSVPAPDPSSPPSQVEEAGEQTWQGNILPNPALPPVSLPNSLIASSAAPSLDPTEGQGCERTSQSVDPFIQPADFGPSEPPLSVPQPFLPVFTMTLLSPGPAPAPVPTALPLVSPPAPTLNPPTPPAFLQTQTFAGVSTSSPVITHTASATLTHDASATTFSQSQGLVITAHHPTPSPSPCGLALSPIPQPPAVGPPQPHLTFIHPKPVSLTGVRHKQPPKIVPAPKPEAVSLVLKSACIAPAAFTGQPQKVIMTSAPLKREGILASTVSPSSVVIASAAITRASGVTEFLSHSTSSQPSPASRLFSPSAVQDALVKGEQAALHGGPQAPATGSSRDCPNSGQASPCPSEQSPSPQSPQNNCSGKSTDPKNVAALKNRQKHISAEQKRRFNIRMGFNTLNSLISNNSKQTSHAITLQKTMEYITKLQQERMQMQEEARRLREEIEELNTTIISCQQLLPATGVPVNCRQFDHMKDMFDEYVKSRILQNWKFWIFSMIIKPLFESFKGMVSTSSLEEFHRTALSWLDQHCSLPVLRPMVLSTLRQLSTTTSILTDPSQLPEQASEAVTRIGKRSGES", "length": 926 }, "evidence": [ { "id": "E1BIZ7", "url": "https://omabrowser.org/oma/group/E1BIZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2VPU4-1", "protein_name": "MLX-interacting protein", "gene_name": "Mlxip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADVFMCSPRRPRSRGRSVLLKPQVPEDDDDSDTDEPSPPPPSGVATSARAHASAAPLPPRAGPGREEPPRRQQIIHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRRNPVCHFVTPLDGSVDVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDEDLSSLAQDDDMLYWHKHGDGWKTPVPMEEDSLLDTDMLMSEFSDTLFSTLSSHQPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPPPSSLPAADPSSPPSQGNILPNTALPPASLPNSLITSSAAPSLDPTEGQGCERTSQTVDPFIQPADFGPSEPPLSVPQPFLPVFTMTLLSPGPAPAPVPTALPLVPSPAPTLNPPTPPAFLQPQKFAGVSKSTPVITHTASATLTHDASATTFSQNQGLVITAHHPTPSSSPCALALSPVPQPPAVGPPQPHLTFIHPKPVSLTGVRHKQPPKIVPAPKPEPVSLVLKNACIAPAAFSGQPQKVIMTSAPLKREGILASTVSPSNVVIASAAITRASGVTEFLSHSTSSQPSPVSRLFSPSTVQDSLVKGEQVSLHGGSPQVPATGSSRDCPNSGQASPCPSEQSPSPQSPQNNCSGKSTDPKNVAALKNRQKHISAEQKRRFNIRMGFNTLNSLISNNSKQTSHAITLQKTMEYITKLQQERMQMQEEARRLREEIEELNTTIISCQQLLPATGVPVNCRQLDHMRDMFDEYVKSRTLQNWKFWIFSMIIKPLFESFKGMVSTSSLEEFHRTALSWLDQHCSLPVLRPMVLSTLRQLSTTTSILTDPSQLPEQASEAVTRMGKRSGES", "length": 917 }, "evidence": [ { "id": "E1BIZ7", "url": "https://omabrowser.org/oma/group/E1BIZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HAP2-1", "protein_name": "MLX-interacting protein", "gene_name": "MLXIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAADVFMCSPRRPRSRGRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPPPRAGPGREEPPRRQQIIHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDEDLSSLVQDDDMLYWHKHGDGWKTPVPMEEDPLLDTDMLMSEFSDTLFSTLSSHQPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSPSPQSPQNNCSGKSDPKNVAALKNRQMKHISAEQKRRFNIKMCFDMLNSLISNNSKLTSHAITLQKTVEYITKLQQERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKDMFDEYVKTRTLQNWKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILRPMVLSTLRQLSTSTSILTDPAQLPEQASKAVTRIGKRLGES", "length": 919 }, "evidence": [ { "id": "E1BIZ7", "url": "https://omabrowser.org/oma/group/E1BIZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BIZ7", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "E1BIZ7", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "E1BIZ7", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BIZ7", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BIZ7", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BIZ7", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "E1BIZ7", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 723, "end_pos": 725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 769, "end_pos": 771, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BIZ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 940, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BIZ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BIZ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ7" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 740, "end_pos": 790, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 48, 353 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 723, "end_pos": 725 }, { "start_pos": 769, "end_pos": 771 }, { "start_pos": 812, "end_pos": 814 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJ13-1", "uniprot_ac": "E1BJ13", "uniprot_id": "E1BJ13_BOVIN", "mass": { "chemical_mass": 63384.0, "monoisotopic_mass": 63384.0 }, "refseq": { "ac": "NP_001178962", "name": "synaptotagmin-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178962" }, "gene_names": [ { "name": "SYT3", "type": "recommended", "evidence": [ { "id": "E1BJ13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ] }, { "name": "SYT3", "type": "synonym", "evidence": [ { "id": "NP_001178962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178962" } ] } ], "protein_names": [ { "name": "Synaptotagmin 3", "type": "synonym", "evidence": [ { "id": "E1BJ13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ13/entry#names_and_taxonomy" } ] }, { "name": "synaptotagmin III", "type": "synonym", "evidence": [ { "id": "NP_001178962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178962" } ] }, { "name": "synaptotagmin-3", "type": "synonym", "evidence": [ { "id": "NP_001178962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178962" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SYT3", "url": "https://www.uniprot.org/uniprotkb/E1BJ13", "locus": { "chromosome": "18", "start_pos": 56713493, "end_pos": 56728122, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013105", "url": "https://www.ensembl.org/id/ENSBTAG00000013105" } ] } } ], "crossref": [ { "id": "E1BJ13", "url": "https://alphafold.ebi.ac.uk/entry/E1BJ13", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013105", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013105", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08403", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08403", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538513", "url": "https://www.ncbi.nlm.nih.gov/gene/538513", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538513", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538513", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SHNERCD", "url": "https://omabrowser.org/oma/group/SHNERCD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJ13", "url": "https://www.orthodb.org/?gene=E1BJ13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024:SF176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024:SF176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178962", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178962", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ13-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGDYEDDLCRRALILVSDLCARVRDADTSDRCQEFNDLRIRGYPRGPDADISVSLLSVIVTFCGIVLLGVSLFVSWKLCWVPWRDKGGSTVGGGPLRKDLGPGVGLAGLVGGGGHHLGAGLGGHPLLGGPHHHAHTAHHPPFAELLEPGSLGGSDPPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTPQPDPGSEERPPALTLPLPGGEEKAKLIGQIKPELYQGTGPGGRRGGGAPGSGEAGAGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTLTSFTKGSKGLSEKENSE", "length": 591, "header": "tr|E1BJ13-1|E1BJ13_BOVIN Isoform 1 of Synaptotagmin 3 OS=Bos taurus OX=9913 GN=SYT3 PE=3 SV=2 CANONICAL=E1BJ13-1" }, "isoforms": [ { "isoform_ac": "E1BJ13-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ13/entry#E1BJ13-1", "sequence": { "sequence": "MSGDYEDDLCRRALILVSDLCARVRDADTSDRCQEFNDLRIRGYPRGPDADISVSLLSVIVTFCGIVLLGVSLFVSWKLCWVPWRDKGGSTVGGGPLRKDLGPGVGLAGLVGGGGHHLGAGLGGHPLLGGPHHHAHTAHHPPFAELLEPGSLGGSDPPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTPQPDPGSEERPPALTLPLPGGEEKAKLIGQIKPELYQGTGPGGRRGGGAPGSGEAGAGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTLTSFTKGSKGLSEKENSE", "length": 591, "header": "tr|E1BJ13-1|E1BJ13_BOVIN Isoform 1 of Synaptotagmin 3 OS=Bos taurus OX=9913 GN=SYT3 PE=3 SV=2 CANONICAL=E1BJ13-1" }, "locus": { "chromosome": "18", "start_pos": 56725821, "end_pos": 56714159, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017422.7", "url": "https://www.ensembl.org/id/ENSBTAT00000017422.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017422.5", "url": "https://www.ensembl.org/id/ENSBTAP00000017422.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538513", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538513", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LDX8-1", "protein_name": "Synaptotagmin-3", "gene_name": "Syt3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNELRIRGYPRGPDADISVSLLSVIVTFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLAPGVGLAGLVGGGGHHLGASLGGHPLLGGPHHHAHTAHHPPFAELLEPGGLGGAEPPEPSYLDMDSYPEAAVASVVAAGVKPSQTSPELPSEGGTGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTTQADPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRGGGGSGEAGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDILEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPEAADPHGREHWAEMLANPRKPVEHWHQLVEEKTLTSFTKGSKGLSEKENSE", "length": 588 }, "evidence": [ { "id": "E1BJ13", "url": "https://omabrowser.org/oma/group/E1BJ13/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1RH13-1", "protein_name": "Synaptotagmin 3", "gene_name": "SYT3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGDYEDDLCRRALILVSDLCARVRDADTSDRCQEFNDLRIRGYPRGPDADISVSLLSVIVTFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLGAGLGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGTDPPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTPQPDPGSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRAGGAPGSGEAGAGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTLTSFTKGSKGLSEKENSE", "length": 591 }, "evidence": [ { "id": "E1BJ13", "url": "https://omabrowser.org/oma/group/E1BJ13/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3IS33-1", "protein_name": "Synaptotagmin-C isoform X1", "gene_name": "syt3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGDWDDDICKRAMVLVEELCFRSGGLSQSASCQEFSYMMRGPNRQINTEISVSLLSVIVTFCGIVLLSVSLFVSWKLCWLPWRDKEGGGLSLTSGLLPGGAGLGGVGGGGGASLLPPLLQRKDTHSSSSLYPTLSQQGQHHPHFSDVMGVEGGGGLVVGGVVGGPQEMQEHSYLDMDSYPNNAATLKLSQTSPELPPATEGGSAAKDLPNAHSQQQVTTRPKPMTHQLSSPDFHGEEKSEQLTSIGQIKPELYRLRQGDQGDGKQGNNCGKISFLLRYAFNTEQLVVKILKALDLPAKDANGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFGVPLAELHARKLHFSVYDFDRFSRHDLIGQVVVDNLLDFSEGTGEKPIWRDIVEGTAEKADLGELNFSLCYLPTAGRLTVTIIKATNLKAMDLTGFSDPYVKASLVCEGRRLKKRKTSIKKNTLNPTYNEALVFDIPNENIESVSLIIAVMDYDCIGHNEVIGMCRMGSDADGPGREHWTAMLANPRKPIEHWHQLVEEKSINTYVSKSAAPSPKPNIVVDSPHSE", "length": 566 }, "evidence": [ { "id": "E1BJ13", "url": "https://omabrowser.org/oma/group/E1BJ13/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35681-1", "protein_name": "Synaptotagmin-3", "gene_name": "Syt3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNELRIRGYPRGPDADISVSLLSVIVTFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLAPGVGLAGLVGGGGHHLGASLGGHPLLGGPHHHGHTAHHPPFAELLEPGGLGGSEPPEPSYLDMDSYPEAAVASVVAAGVKPSQTSPELPSEGGTGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTTQADPSTEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRGGGSGEAGAPCGRISFALRYLYGSDHLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDILEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPEAADPHGREHWAEMLANPRKPVEHWHQLVEEKTLSSFTKGGKGLSEKENSE", "length": 587 }, "evidence": [ { "id": "E1BJ13", "url": "https://omabrowser.org/oma/group/E1BJ13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P40748-1", "protein_name": "Synaptotagmin-3", "gene_name": "Syt3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDYEDDLCRRALILVSDLCARIRDADTNDRCQEFNELRIRGYPRGPDADISVSLLSVIVTFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLAPGVGLAGLVGGGGHHLGASLGGHPLLGGPHHHAHPAHHPPFAELLEPGGLGGSEPPEPSYLDMDSYPEAAVASVVAAGVKPSQTSPELPSEGGTGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTTQADPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRTGGGSGEAGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDILEGGSEKADLGELNFSLCYLPTAGLLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPEAADPHGREHWAEMLANPRKPVEHWHQLVEEKTLSSFTKGGKGLSEKENSE", "length": 588 }, "evidence": [ { "id": "E1BJ13", "url": "https://omabrowser.org/oma/group/E1BJ13/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BQG1-1", "protein_name": "Synaptotagmin-3", "gene_name": "SYT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIVTFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE", "length": 590 }, "evidence": [ { "id": "E1BJ13", "url": "https://omabrowser.org/oma/group/E1BJ13/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of dendrite extension", "id": "GO:1903861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903861", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" }, { "name": "positive regulation of vesicle fusion", "id": "GO:0031340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031340", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" }, { "name": "regulation of calcium ion-dependent exocytosis", "id": "GO:0017158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017158", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "E1BJ13", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJ13-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 591, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJ13-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJ13" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJ13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ13" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 300, "end_pos": 421, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 366, "end_pos": 368 }, { "start_pos": 437, "end_pos": 439 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJ18-1", "uniprot_ac": "E1BJ18", "uniprot_id": "E1BJ18_BOVIN", "mass": { "chemical_mass": 74980.0, "monoisotopic_mass": 74980.0 }, "refseq": { "ac": "NP_001179160", "name": "calpain-6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179160" }, "gene_names": [ { "name": "CAPN6", "type": "recommended", "evidence": [ { "id": "E1BJ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ18" } ] }, { "name": "CAPN6", "type": "synonym", "evidence": [ { "id": "NP_001179160", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179160" } ] } ], "protein_names": [ { "name": "Calpain-6", "type": "recommended", "evidence": [ { "id": "E1BJ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ18/entry#names_and_taxonomy" } ] }, { "name": "calpain-6", "type": "synonym", "evidence": [ { "id": "NP_001179160", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179160" } ] } ], "function": [ { "annotation": "Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues.", "evidence": [ { "database": "UniProtKB", "id": "E1BJ18", "url": "https://www.uniprot.org/uniprotkb/E1BJ18#function" }, { "database": "UniProtKB", "id": "ARBA00058712", "url": "https://www.uniprot.org/uniprotkb/ARBA00058712#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJ18", "url": "https://www.uniprot.org/uniprotkb/E1BJ18" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CAPN6", "url": "https://www.uniprot.org/uniprotkb/E1BJ18", "locus": { "chromosome": "X", "start_pos": 59414790, "end_pos": 59439446, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000828", "url": "https://www.ensembl.org/id/ENSBTAG00000000828" } ] } } ], "crossref": [ { "id": "E1BJ18", "url": "https://alphafold.ebi.ac.uk/entry/E1BJ18", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000828", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000828", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04046", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04046", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539360", "url": "https://www.ncbi.nlm.nih.gov/gene/539360", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539360", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539360", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKGRYTD", "url": "https://omabrowser.org/oma/group/QKGRYTD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJ18", "url": "https://www.orthodb.org/?gene=E1BJ18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183:SF381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183:SF381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1474228", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1474228", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179160", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179160", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BJ18", "url": "https://www.uniprot.org/uniprotkb/E1BJ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ18-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPPLKFFKNQKYQELKQECIRDGRLFCDPTFLPENDSLFYNRLLPGKVIWKRPQDICDDPRLIVGNISNHQLTQGRLGHKPMVSAFSCLAVQECHWTKTIPNYKEQEWDPRKIDKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTTSDIIVDFTGTLAETVDMQKGRYTDLVEEKYKLFKELYKTFTKGGLICCSIEFPDQEEQEVETDWGLLKGHTYTMTDIRKIRLGERLVEVFSTEKLYMIRLRNPLGRQEWSGPWSEISEEWQQLTAADRKNLGIVMSDDGEFWMSLEDFCRNFHELNVCRNVNNPLFGHKELESVVGCWTVNDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDEHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVELNRKFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFCEVPVQLRELTMDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYDNETVNPYLIIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIVQVWNKRKFCDQFLGQVILDADPSDCRELKSLYLRKKGGPTAKVKQGHISFKIISSDDLTEL", "length": 641, "header": "tr|E1BJ18-1|E1BJ18_BOVIN Isoform 1 of Calpain-6 OS=Bos taurus OX=9913 GN=CAPN6 PE=3 SV=1 CANONICAL=E1BJ18-1" }, "isoforms": [ { "isoform_ac": "E1BJ18-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ18/entry#E1BJ18-1", "sequence": { "sequence": "MGPPLKFFKNQKYQELKQECIRDGRLFCDPTFLPENDSLFYNRLLPGKVIWKRPQDICDDPRLIVGNISNHQLTQGRLGHKPMVSAFSCLAVQECHWTKTIPNYKEQEWDPRKIDKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTTSDIIVDFTGTLAETVDMQKGRYTDLVEEKYKLFKELYKTFTKGGLICCSIEFPDQEEQEVETDWGLLKGHTYTMTDIRKIRLGERLVEVFSTEKLYMIRLRNPLGRQEWSGPWSEISEEWQQLTAADRKNLGIVMSDDGEFWMSLEDFCRNFHELNVCRNVNNPLFGHKELESVVGCWTVNDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDEHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVELNRKFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFCEVPVQLRELTMDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYDNETVNPYLIIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIVQVWNKRKFCDQFLGQVILDADPSDCRELKSLYLRKKGGPTAKVKQGHISFKIISSDDLTEL", "length": 641, "header": "tr|E1BJ18-1|E1BJ18_BOVIN Isoform 1 of Calpain-6 OS=Bos taurus OX=9913 GN=CAPN6 PE=3 SV=1 CANONICAL=E1BJ18-1" }, "locus": { "chromosome": "X", "start_pos": 59432920, "end_pos": 59415226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001094.6", "url": "https://www.ensembl.org/id/ENSBTAT00000001094.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001094.4", "url": "https://www.ensembl.org/id/ENSBTAP00000001094.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539360", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539360", "resource": "KEGG Pathway" }, { "id": "R-BTA-1474228", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1474228", "resource": "Reactome", "description": "Degradation of the extracellular matrix" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YSC4-1", "protein_name": "Calpain 6", "gene_name": "CAPN6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSSVQLFRDQKYHELKRQCIQQGQLFEDPEFPASDESLFYQKVPRGKVEWKRPKDLCQDPYLFVNGISSHDLHQGSLGNCWFVAACSCLALRKKLWQQVIPDFQEQEWDPKTPEKYAGIFRFRFWCFGIWTEVVIDDLLPTIDGTLIYCHSNVENEFWSALLEKAYAKLAGSYEALDGGSAADAIVDFTGAVAESIDLVQGKYSETISEQMKLFEDLLKVHKRGGLISCFIASSSGRANEVEAKTGLVTGHAYSVTAIRKVHLGERLTFSFKAEKLFMVRLRNPWGNREWNGAWSDNSEEWKKVSNAERKSLGLTVENDGEFWMTFEDWCKNFTDVDVCRIVNTSYFSIHKTWETKMMHGAWTENSEPLLNRCGGCFDNIETFLQNPQYIFDVKKTEDKVLISLQQEDRRRSKKVGKGDNITIGFEIFKVEDNRSYRLHKLTVQERVATSPYINTRNVFLKKILKQGRYILIPTTYLPGITAKFILRLFTDVPSKLRELTADKPEMTCWSLLCGYPRRITQIKIHSAEGLQEQDGSSGADPYVLIKCENQKVRSSVQHNTTSAIFNTQVIFYRKNIDSPVIVQVWNSNILCDQFLGQALLAASPSDPREQQTLQLRGRGSQEAEEVPGHITVKVFSTDDLVEL", "length": 644 }, "evidence": [ { "id": "E1BJ18", "url": "https://omabrowser.org/oma/group/E1BJ18/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RWU4-1", "protein_name": "Calpain-6", "gene_name": "CAPN6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGPPLKLFKNQKYQELKQECIRDGRLFCDPTFLPENDSLFYNRLLPGKVVWKRPQDICDDPRLIVGNISNHQLIQGRLGHKPMVSAFSCLAVQESHWTKTIPNHKEQEWDPRKLDKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTTTDIIVDFTGTLAETVDMQKGRYTELVEEKYKLFGELYKTFTKGGLICCSIESPNQEEQEVETDWGLLKGHTYTMTDIRKIRLGERLVEVFSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTAADRKNLGLVMSDDGEFWMSLEDFCRNFHELSVCRNVNNPIFGRKELESVVGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRKFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLVIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIVQVWNRRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTEL", "length": 641 }, "evidence": [ { "id": "E1BJ18", "url": "https://omabrowser.org/oma/group/E1BJ18/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35646-1", "protein_name": "Calpain-6", "gene_name": "Capn6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPPLKLFKNQKYQELKQECMKDGRLFCDPTFLPENDSLFFNRLLPGKVVWKRPQDISDDPHLIVGNISNHQLIQGRLGNKAMISAFSCLAVQESHWTKAIPNHKDQEWDPRKPEKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIMDFTGTLAEIIDMQKGRYTDLVEEKYKLFGELYKTFTKGGLICCSIESPSQEEQEVETDWGLLKGYTYTMTDIRKLRLGERLVEVFSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTVTDRKNLGLVMSDDGEFWMSLEDFCHNFHKLNVCRNVNNPVFGRKELESVVGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRRFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGSYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLIIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIIQVWNSRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTEL", "length": 641 }, "evidence": [ { "id": "E1BJ18", "url": "https://omabrowser.org/oma/group/E1BJ18/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O88501-1", "protein_name": "Calpain-6", "gene_name": "Capn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPPLKLFKNQKYQELKQDCMKDGRLFCDPTFLPENDSLFFNRLLPGKVVWKRPQDISDDPHLIVGNISNHQLIQGRLGNKAMISAFSCLAVQESHWTKAIPNHKEQEWDPRKPEKYAGIFRFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIMDFTGTLAEIIDMQKGRYTDLVEEKYKLFGELYKTFTKGGLISCSIESPSQEEQEVETDWGLLKGYTYTMTDIRKLRLGERLVEVFSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTVTDRKNLGLVMSDDGEFWMSLEDFCHNFHKLNVCRNVNNPVFGRKELESVVGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRRFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLTIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIIQVWNSRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTEL", "length": 641 }, "evidence": [ { "id": "E1BJ18", "url": "https://omabrowser.org/oma/group/E1BJ18/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y6Q1-1", "protein_name": "Calpain-6", "gene_name": "CAPN6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPPLKLFKNQKYQELKQECIKDSRLFCDPTFLPENDSLFYNRLLPGKVVWKRPQDICDDPHLIVGNISNHQLTQGRLGHKPMVSAFSCLAVQESHWTKTIPNHKEQEWDPQKTEKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIVDFTGTLAETVDMQKGRYTELVEEKYKLFGELYKTFTKGGLICCSIESPNQEEQEVETDWGLLKGHTYTMTDIRKIRLGERLVEVFSAEKVYMVRLRNPLGRQEWSGPWSEISEEWQQLTASDRKNLGLVMSDDGEFWMSLEDFCRNFHKLNVCRNVNNPIFGRKELESVLGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRKFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEDLEKKYANETVNPYLVIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIVQVWNSRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTEL", "length": 641 }, "evidence": [ { "id": "E1BJ18", "url": "https://omabrowser.org/oma/group/E1BJ18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BJ18", "url": "https://www.uniprot.org/uniprotkb/E1BJ18" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1BJ18", "url": "https://www.uniprot.org/uniprotkb/E1BJ18" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "E1BJ18", "url": "https://www.uniprot.org/uniprotkb/E1BJ18" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BJ18", "url": "https://www.uniprot.org/uniprotkb/E1BJ18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of cytoskeleton organization", "id": "GO:0051493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051493", "evidence": [ { "database": "UniProtKB", "id": "E1BJ18", "url": "https://www.uniprot.org/uniprotkb/E1BJ18" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "E1BJ18", "url": "https://www.uniprot.org/uniprotkb/E1BJ18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJ18-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 641, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJ18-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJ18" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ18" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 498, "end_pos": 613, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ18" }, { "id": "PS50203", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calpain catalytic", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 343, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 369, "end_pos": 371 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJ35-1", "uniprot_ac": "E1BJ35", "uniprot_id": "E1BJ35_BOVIN", "mass": { "chemical_mass": 56367.0, "monoisotopic_mass": 56367.0 }, "refseq": { "ac": "XP_024839800", "name": "chorion-specific transcription factor GCMb", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839800" }, "gene_names": [ { "name": "GCM2", "type": "recommended", "evidence": [ { "id": "E1BJ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ35" } ] }, { "name": "GCM2", "type": "synonym", "evidence": [ { "id": "XP_024839800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839800" } ] } ], "protein_names": [ { "name": "Glial cells missing transcription factor 2", "type": "synonym", "evidence": [ { "id": "E1BJ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ35/entry#names_and_taxonomy" } ] }, { "name": "chorion-specific transcription factor GCMb", "type": "synonym", "evidence": [ { "id": "XP_024839800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839800" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJ35", "url": "https://www.uniprot.org/uniprotkb/E1BJ35" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GCM2", "url": "https://www.uniprot.org/uniprotkb/E1BJ35", "locus": { "chromosome": "23", "start_pos": 45334291, "end_pos": 45326999, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018787", "url": "https://www.ensembl.org/id/ENSBTAG00000018787" } ] } } ], "crossref": [ { "id": "E1BJ35", "url": "https://alphafold.ebi.ac.uk/entry/E1BJ35", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018787", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018787", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539454", "url": "https://www.ncbi.nlm.nih.gov/gene/539454", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539454", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539454", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEPKHFD", "url": "https://omabrowser.org/oma/group/QEPKHFD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJ35", "url": "https://www.orthodb.org/?gene=E1BJ35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12414", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12414", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12414:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12414:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024839800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839800", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BJ35", "url": "https://www.uniprot.org/uniprotkb/E1BJ35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ35-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAPEAQLADCAWSYGMKLSWDINDPQMPQKPAHFDRFCEWPDGYVRFIYSSDEKKAQRHLSGWAMRNTNNHNGHILKKSCLGVVVCAQDCALPDGSRLQLRPAICDKARLKQQKKPCPNCHSALELIPCRGHSGYPVTNFWRLDGNAIFFQAKGVHDHPRPESKSETEARRSAIKRQMASFYQPQKRRIREPEAGENQDHSRHFNNIPSLENPEGLDVIPDAGFPVSGQHCLSFPNSDACKATCDLTTFQGDIVPPFQKYSNPRIYLPRPPCSYELAGPGYANSSPYPTFYKDAGSIPKDSDWVQLNALPYNVNTYSSFERSCDFTSNQHSWKPALGKAGPGERMDQGQFPVEATHPQHTPQPPCRYLATAPPAAPALQTVITTTTRVSYQACQPPTLKCCDNVRDAKSLSSCDYASENTQMSIYPGALDFPAPVVTTSSPTASLPLKIPRDCWTVRQHSLPYPLGAAPSRTDGAEAWEVCSSRLGSAANYSDRISPFFSCDNEDF", "length": 507, "header": "tr|E1BJ35-1|E1BJ35_BOVIN Isoform 1 of Glial cells missing transcription factor 2 OS=Bos taurus OX=9913 GN=GCM2 PE=4 SV=3 CANONICAL=E1BJ35-1" }, "isoforms": [ { "isoform_ac": "E1BJ35-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ35/entry#E1BJ35-1", "sequence": { "sequence": "MPAPEAQLADCAWSYGMKLSWDINDPQMPQKPAHFDRFCEWPDGYVRFIYSSDEKKAQRHLSGWAMRNTNNHNGHILKKSCLGVVVCAQDCALPDGSRLQLRPAICDKARLKQQKKPCPNCHSALELIPCRGHSGYPVTNFWRLDGNAIFFQAKGVHDHPRPESKSETEARRSAIKRQMASFYQPQKRRIREPEAGENQDHSRHFNNIPSLENPEGLDVIPDAGFPVSGQHCLSFPNSDACKATCDLTTFQGDIVPPFQKYSNPRIYLPRPPCSYELAGPGYANSSPYPTFYKDAGSIPKDSDWVQLNALPYNVNTYSSFERSCDFTSNQHSWKPALGKAGPGERMDQGQFPVEATHPQHTPQPPCRYLATAPPAAPALQTVITTTTRVSYQACQPPTLKCCDNVRDAKSLSSCDYASENTQMSIYPGALDFPAPVVTTSSPTASLPLKIPRDCWTVRQHSLPYPLGAAPSRTDGAEAWEVCSSRLGSAANYSDRISPFFSCDNEDF", "length": 507, "header": "tr|E1BJ35-1|E1BJ35_BOVIN Isoform 1 of Glial cells missing transcription factor 2 OS=Bos taurus OX=9913 GN=GCM2 PE=4 SV=3 CANONICAL=E1BJ35-1" }, "locus": { "chromosome": "23", "start_pos": 45333287, "end_pos": 45327198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025010.4", "url": "https://www.ensembl.org/id/ENSBTAT00000025010.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025010.3", "url": "https://www.ensembl.org/id/ENSBTAP00000025010.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539454", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539454", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZXW4-1", "protein_name": "Glial cells missing transcription factor 2", "gene_name": "Gcm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPADSMQDPDPVLSYGMKLTWDINDPQMPQEPAHFDHFREWPDGYVRFIYSSQEKKAQRHLSGWAMRNTNNHNGHILKKSCLGVVVCARACALKDGSHLQLRPAICDKARLKQQKKACPNCHSALELVPCRGHSGYPVTNFWRLDGNAIFFQAKGVHDHPRPESKSETEGRRSALKRQMASFYQPQKRRSEEPEAGSTQDTRGHSNSTPVPEPSELFAMPADTSFPISGHSSLSFPNSDVHRVTCDLPTFPGDVILPFQKYSNPSIYFPGPPWSYELASPGVTGSSPYPTLYKDPSIVPDDPDWIHLNSLQYNVSSYGSYERSLDLTARYHGWKPTHGKAGLEEKVDCRPCQAVPTSPYYNLELPCRYLPVAPAGTQALQTVITTTVAYQAYQHPALKHGDSVQEVSSLASCTYASENLPMPIYPQALDPQEGAIQAASPSGRAPGIVPGDCQAARPTLAFPQETDPSRTAGADVWDVCLSGVGSVMAYLDRTGQPFNLDNEDF", "length": 504 }, "evidence": [ { "id": "E1BJ35", "url": "https://omabrowser.org/oma/group/E1BJ35/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O09102-1", "protein_name": "Chorion-specific transcription factor GCMb", "gene_name": "Gcm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJ64-1", "uniprot_ac": "E1BJ64", "uniprot_id": "E1BJ64_BOVIN", "mass": { "chemical_mass": 9216.0, "monoisotopic_mass": 9216.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ubiquitin-like protein NEDD8", "type": "recommended", "evidence": [ { "id": "E1BJ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ64/entry#names_and_taxonomy" } ] }, { "name": "Neddylin", "type": "synonym", "evidence": [ { "id": "E1BJ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ64/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis via its conjugation to a limited number of cellular proteins, such as cullins or p53/TP53. Attachment of NEDD8 to cullins is critical for the recruitment of E2 to the cullin-RING-based E3 ubiquitin-protein ligase complex, thus facilitating polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. Attachment of NEDD8 to p53/TP53 inhibits p53/TP53 transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M.", "evidence": [ { "database": "UniProtKB", "id": "E1BJ64", "url": "https://www.uniprot.org/uniprotkb/E1BJ64#function" }, { "database": "UniProtKB", "id": "ARBA00045599", "url": "https://www.uniprot.org/uniprotkb/ARBA00045599#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJ64", "url": "https://www.uniprot.org/uniprotkb/E1BJ64" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BJ64", "locus": {} } ], "crossref": [ { "id": "E1BJ64", "url": "https://alphafold.ebi.ac.uk/entry/E1BJ64", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021446", "url": 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Classification" ] }, { "id": "DMESTDK", "url": "https://omabrowser.org/oma/group/DMESTDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BJ64", "url": "https://www.uniprot.org/uniprotkb/E1BJ64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ64-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLIKVKTLTRKEIEIDTEPTDKVEQIKERVKEKEGIPPEQQRLTYSGRQINVKKTSTDYRLLSGSVLHLVLALRGGGGLRQ", "length": 81, "header": "tr|E1BJ64-1|E1BJ64_BOVIN Isoform 1 of Ubiquitin-like protein NEDD8 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BJ64-1" }, 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kinetochore-associated protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211616" }, "gene_names": [ { "name": "KNSTRN", "type": "recommended", "evidence": [ { "id": "E1BJ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ69" } ] }, { "name": "C10H15orf23", "type": "synonym", "evidence": [ { "id": "XP_005211616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211616" } ] }, { "name": "KNSTRN", "type": "synonym", "evidence": [ { "id": "XP_005211616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211616" } ] } ], "protein_names": [ { "name": "Kinetochore localized astrin (SPAG5) binding protein", "type": "synonym", "evidence": [ { "id": "E1BJ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ69/entry#names_and_taxonomy" } ] }, { "name": "small kinetochore-associated protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005211616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211616" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJ69", "url": "https://www.uniprot.org/uniprotkb/E1BJ69" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KNSTRN", "url": "https://www.uniprot.org/uniprotkb/E1BJ69", "locus": { "chromosome": "10", "start_pos": 36009981, "end_pos": 35999923, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000032340", "url": "https://www.ensembl.org/id/ENSBTAG00000032340" } ] } } ], "crossref": [ { "id": "E1BJ69", "url": "https://alphafold.ebi.ac.uk/entry/E1BJ69", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000032340", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000032340", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507864", "url": "https://www.ncbi.nlm.nih.gov/gene/507864", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31940", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31940", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31940:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31940:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28427", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28427", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005211616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211616", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BJ69", "url": "https://www.uniprot.org/uniprotkb/E1BJ69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ69-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPVAHSSIKDGKVHHFPSPAQTWGLLYPAPGSSNSGIDSDLPYSMAAAEDVAHASDCRTTWPPTESAPHLLPPGRRKFPFETQAADAVGGTAVIAEHLLNQSDEACGQEQQAPGPQPCRLVTMTSVVKTVYTLQPSCVLSSGLPADAQTRATFKSQLPVKSKEVDVSRPHSGASENDVTKIIKPRRENGQVKATDTSRRNLRKSYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLIETQGELKDLTQKVELLEKFQDNCLAILESKGLNPGSETLASQQDSTADHVDSMLLLQTLQDELKLFNETAKKQMKELQALKVKLKMKEEERAQFLEQQTLCSNQVNDFTTALEEMEQLLEI", "length": 358, "header": "tr|E1BJ69-1|E1BJ69_BOVIN Isoform 1 of Kinetochore localized astrin (SPAG5) binding protein OS=Bos taurus OX=9913 GN=KNSTRN PE=4 SV=3 CANONICAL=E1BJ69-1" }, "isoforms": [ { "isoform_ac": "E1BJ69-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ69/entry#E1BJ69-1", "sequence": { "sequence": "MTPVAHSSIKDGKVHHFPSPAQTWGLLYPAPGSSNSGIDSDLPYSMAAAEDVAHASDCRTTWPPTESAPHLLPPGRRKFPFETQAADAVGGTAVIAEHLLNQSDEACGQEQQAPGPQPCRLVTMTSVVKTVYTLQPSCVLSSGLPADAQTRATFKSQLPVKSKEVDVSRPHSGASENDVTKIIKPRRENGQVKATDTSRRNLRKSYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLIETQGELKDLTQKVELLEKFQDNCLAILESKGLNPGSETLASQQDSTADHVDSMLLLQTLQDELKLFNETAKKQMKELQALKVKLKMKEEERAQFLEQQTLCSNQVNDFTTALEEMEQLLEI", "length": 358, "header": "tr|E1BJ69-1|E1BJ69_BOVIN Isoform 1 of Kinetochore localized astrin (SPAG5) binding protein OS=Bos taurus OX=9913 GN=KNSTRN PE=4 SV=3 CANONICAL=E1BJ69-1" }, "locus": { "chromosome": "10", "start_pos": 36009408, "end_pos": 36000122, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056746.4", "url": "https://www.ensembl.org/id/ENSBTAT00000056746.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050471.3", "url": "https://www.ensembl.org/id/ENSBTAP00000050471.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "E1BJ69", "url": "https://www.uniprot.org/uniprotkb/E1BJ69" } ], "pmid": "" }, { "name": "regulation of attachment of spindle microtubules to kinetochore", "id": "GO:0051988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051988", "evidence": [ { "database": "UniProtKB", "id": "E1BJ69", "url": "https://www.uniprot.org/uniprotkb/E1BJ69" } ], "pmid": "" }, { "name": "cellular response to epidermal growth factor stimulus", "id": "GO:0071364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071364", "evidence": [ { "database": "UniProtKB", "id": "E1BJ69", "url": "https://www.uniprot.org/uniprotkb/E1BJ69" } ], "pmid": "" }, { "name": "spindle organization", "id": "GO:0007051", "url": 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"Cellular Component", "total": 5, "go_terms": [ { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "E1BJ69", "url": "https://www.uniprot.org/uniprotkb/E1BJ69" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "E1BJ69", "url": "https://www.uniprot.org/uniprotkb/E1BJ69" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "E1BJ69", "url": "https://www.uniprot.org/uniprotkb/E1BJ69" } ], "pmid": "" }, { "name": "microtubule plus-end", "id": "GO:0035371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035371", "evidence": [ { "database": "UniProtKB", "id": "E1BJ69", "url": "https://www.uniprot.org/uniprotkb/E1BJ69" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "E1BJ69", "url": "https://www.uniprot.org/uniprotkb/E1BJ69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJ69-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 358, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJ69-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJ69" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], 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"MEQSLERALDLAESVIESAQQRPPKRKNSSGEMSLHEKLYDIYVEESEKEPEVAEELRSNVNLLEKLLRRESLPCLVVNLYPGKRGYSLMLKGENESFTESIQLPYEEGELLEYLDAQELPPVLMNLLEKSLVNVFHEGCVIAEIRNYRQFSEGEPPSYQSRHILLRPTMQTLACDVEAIASDHHNWTQEDKLLLESQLILATAEPLCLDPFVSVACTENRLLYNKQKLNTRPMKRNLKRFSTASLNRQQDFPPSPLPPELTALPSLAKSQESKTDKQYDLKTLKAGKCVDTWKQRPCDLAVPSEVDVEKHTKSFKYDDLQPTVWPTYEVGEDSIFGYEDSSHSPATKQMLMHPLNDPLISGKSMPHKKKRKVVYERQMSPYHSFTDDHPCNFLSGPETDDVRMVSPSEESSQKKQPMTGSVQQPFPGKEPEQPKNGSVQSSVLGKGAKHPPSPIRLPLNPGKSSWGDSFTSQQASSSHKFPSPASAPKLPSLSQESSMEVSQVSSFPAMALSTVGSSQRTEASATSSGLNITKEVQPGGGGLALGSSSKPVQDSTTAPAGITVGPFPRGIKLSLLPTGISLGPLPGPLPIGIQPDSQPTGMKPGPLLMPFTLLQLSPGSLILNPQQAQEQLQQPTQQWLYQLMPQPQLQQPTTSHPPQSVPQDPAEGSGSQMALSAQQAMVLQPQAVLLSQVGSAQRGPRPSLPQHRVQLASTLQLHPQPRPVQFRILQHPVAVATVVAPAAQPQPPGEQTASQSKGQTESTPTPPKS", "length": 769, "header": "tr|E1BJ71-1|E1BJ71_BOVIN Isoform 1 of Spt20-like SEP domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=E1BJ71-1" }, "isoforms": [ { "isoform_ac": "E1BJ71-1", "url": 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CANONICAL=E1BJ71-1" }, "locus": { "chromosome": "X", "start_pos": 114378731, "end_pos": 114374001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053235.2", "url": "https://www.ensembl.org/id/ENSBTAT00000053235.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048167.2", "url": "https://www.ensembl.org/id/ENSBTAP00000048167.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 765, "start_aa": "Thr", "end_pos": 765, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr765", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BJ71", "url": "https://www.uniprot.org/uniprotkb/E1BJ71" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "E1BJ71", "url": "https://www.uniprot.org/uniprotkb/E1BJ71" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "E1BJ71", "url": "https://www.uniprot.org/uniprotkb/E1BJ71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJ71-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 769, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJ71-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJ71" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJ71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ71" }, { "id": "PF12090", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12090" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Spt20-like SEP", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 216, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 765 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 28, "end_pos": 30 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJ80-1", "uniprot_ac": "E1BJ80", "uniprot_id": "E1BJ80_BOVIN", "mass": { "chemical_mass": 36590.0, "monoisotopic_mass": 36590.0 }, "refseq": { "ac": "NP_001070458", "name": "lysophospholipase D GDPD3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070458" }, "gene_names": [ { "name": "GDPD3", "type": "recommended", "evidence": [ { "id": "E1BJ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ80" } ] }, { "name": "GDPD3", "type": "synonym", "evidence": [ { "id": "NP_001070458", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070458" } ] } ], "protein_names": [ { "name": "Lysophospholipase D GDPD3", "type": "recommended", "evidence": [ { "id": "E1BJ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ80/entry#names_and_taxonomy" } ] }, { "name": "Glycerophosphodiester phosphodiesterase 7", "type": "synonym", "evidence": [ { "id": "E1BJ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ80/entry#names_and_taxonomy" } ] }, { "name": "Glycerophosphodiester phosphodiesterase domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "E1BJ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ80/entry#names_and_taxonomy" } ] }, { "name": "lysophospholipase D GDPD3", "type": "synonym", "evidence": [ { "id": "NP_001070458", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070458" } ] } ], "function": [ { "annotation": "Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylcholine (lyso-PC) and N-acylethanolamine lysophospholipids. Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine.", "evidence": [ { "database": "UniProtKB", "id": "E1BJ80", "url": "https://www.uniprot.org/uniprotkb/E1BJ80#function" }, { "database": "UniProtKB", "id": "ARBA00056977", "url": "https://www.uniprot.org/uniprotkb/ARBA00056977#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJ80", "url": "https://www.uniprot.org/uniprotkb/E1BJ80" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GDPD3", "url": "https://www.uniprot.org/uniprotkb/E1BJ80", "locus": { "chromosome": "25", "start_pos": 26191906, "end_pos": 26186549, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016155", "url": "https://www.ensembl.org/id/ENSBTAG00000016155" } ] } } ], "crossref": [ { "id": "E1BJ80", "url": "https://alphafold.ebi.ac.uk/entry/E1BJ80", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016155", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016155", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08612", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08612", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "767913", "url": "https://www.ncbi.nlm.nih.gov/gene/767913", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:767913", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:767913", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KWAIMRK", "url": "https://omabrowser.org/oma/group/KWAIMRK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJ80", "url": "https://www.orthodb.org/?gene=E1BJ80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42758", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42758", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42758:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42758:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070458", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070458", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "41143", "url": "https://www.rhea-db.org/rhea/41143", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45544", "url": "https://www.rhea-db.org/rhea/45544", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53168", "url": "https://www.rhea-db.org/rhea/53168", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53184", "url": "https://www.rhea-db.org/rhea/53184", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56460", "url": "https://www.rhea-db.org/rhea/56460", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BJ80", "url": "https://www.uniprot.org/uniprotkb/E1BJ80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ80-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPLLYYALPALGSYVMLSFFFLRRPRLLHTPWVPAFRPRLGAHRGGSGERLENTMEAMENSMAQRADFLELDCQLTRDGVVVVSHDKNLSRQTGVNRDVGSLNFEDLPLLKEELEVYFSPGHFARGADRHMMRLEDLFRRFPRTPMSVEVKERNEELIHKIACLVRHYDRNEITIWASEKSSIMKKCKAANPEMPTSFTLSRGFWVLLFYYLGLLPFISIPEKFFMCFLPTIINRTYFPFSHPGLNQLAAVVAKWLIMRKSLIQHLQQRGVQVVFWCLNEESDFEAAFNLGATGVITDYPTALRCYLDSRGPPALAS", "length": 318, "header": "tr|E1BJ80-1|E1BJ80_BOVIN Isoform 1 of Lysophospholipase D GDPD3 OS=Bos taurus OX=9913 GN=GDPD3 PE=3 SV=1 CANONICAL=E1BJ80-1" }, "isoforms": [ { "isoform_ac": "E1BJ80-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ80/entry#E1BJ80-1", "sequence": { "sequence": "MSPLLYYALPALGSYVMLSFFFLRRPRLLHTPWVPAFRPRLGAHRGGSGERLENTMEAMENSMAQRADFLELDCQLTRDGVVVVSHDKNLSRQTGVNRDVGSLNFEDLPLLKEELEVYFSPGHFARGADRHMMRLEDLFRRFPRTPMSVEVKERNEELIHKIACLVRHYDRNEITIWASEKSSIMKKCKAANPEMPTSFTLSRGFWVLLFYYLGLLPFISIPEKFFMCFLPTIINRTYFPFSHPGLNQLAAVVAKWLIMRKSLIQHLQQRGVQVVFWCLNEESDFEAAFNLGATGVITDYPTALRCYLDSRGPPALAS", "length": 318, "header": "tr|E1BJ80-1|E1BJ80_BOVIN Isoform 1 of Lysophospholipase D GDPD3 OS=Bos taurus OX=9913 GN=GDPD3 PE=3 SV=1 CANONICAL=E1BJ80-1" }, "locus": { "chromosome": "25", "start_pos": 26191846, "end_pos": 26186568, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045469.5", "url": "https://www.ensembl.org/id/ENSBTAT00000045469.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042857.3", "url": "https://www.ensembl.org/id/ENSBTAP00000042857.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:767913", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:767913", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A1N8-1", "protein_name": "Lysophospholipase D GDPD3", "gene_name": "Gdpd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIPLVYFVLPTLGSYVILSIFFLRRPHLLHTPWAPGFSIRLAAHRGGSGERLENTMEAIENSMAQRADLLEFDCQLTRDGVVVVSHDKNLSRQSGLNKDINTLDFAQLPLYKEELEIYFSPGHFAHGSDRHMISLEDVFQKFPRTPMCLEIKEKNEELIHKVANMARRFNRNEITIWTSEKNSIMKRCKAANPEMPTAFTIWRSFWILLLYYLGLLPFVSIPEKFFFCFLPTIINRTYFPFSCGWMNKLSATVTKWAIMRKSLIQYLQDRGVQVLFWCLNEESDFEVAFSLGANGVMTDYPTALRHYLDKQEQRDSASSV", "length": 320 }, "evidence": [ { "id": "E1BJ80", "url": "https://omabrowser.org/oma/group/E1BJ80/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7L5L3-2", "protein_name": "Lysophospholipase D GDPD3", "gene_name": "GDPD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLLLYYALPALGSYAMLSIFFLRRPHLLHTPRAPTFRIRLGAHRGGSGELLENTMEAMENSMAQRSDLLELDCQLTRDRVVVVSHDENLCRQSGLNRDVGSLDFEDLPLYKEKLEVYFSPGHFAHGSDRRMVRLEDLFQRFPRTPMSVEIKGKNEELIREIAGLVRRYDRNEITIWASEKSSVMKKCKAANPEMPLSFTISRGFWVLLSYYLGLLPFIPIPEKFFFCFLPNIINRTYFPFSCSCLNQLLAVVSKWLIMRKSLIRHLEERGVQVVFWCLNEESDFEAAFSVGATGVITDYPTALRHYLDNHGPAARTS", "length": 318 }, "evidence": [ { "id": "E1BJ80", "url": "https://omabrowser.org/oma/group/E1BJ80/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99LY2-1", "protein_name": "Lysophospholipase D GDPD3", "gene_name": "Gdpd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPLLYFVLPTLGSYVMLSIFFLRRPHLLHTPRAPVFPIRLAAHRGGSGERLENTMEAVENSMAQRADLLEFDCQLTRDGVVVVSHDKNLSRQSGLNKDVNTLDFEELPLYKEELEIYFSPGHFAHGSDRHMISLEDVFQKFPRTPMCLEVKERNEELIHKVANLTRRFDRNEITIWAAEKSSVMKRCRAANPEMPMAFTIWRSFWILLLYYLGLLPFVSIPEKFFFCFLPTIINRTYFPFRCGWMNQLSATITKWIIMRKSLIRHLQDRGVQVLFWCLNEESDFEVAFSLGANGVMTDYPTALRHYLDKQEEETQPPQPEALSCLSLKK", "length": 330 }, "evidence": [ { "id": "E1BJ80", "url": "https://omabrowser.org/oma/group/E1BJ80/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "phosphatidylcholine catabolic process", "id": "GO:0034638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034638", "evidence": [ { "database": "UniProtKB", "id": "E1BJ80", "url": "https://www.uniprot.org/uniprotkb/E1BJ80" } ], "pmid": "" }, { "name": "N-acylethanolamine metabolic process", "id": "GO:0070291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070291", "evidence": [ { "database": "UniProtKB", "id": "E1BJ80", "url": "https://www.uniprot.org/uniprotkb/E1BJ80" } ], "pmid": "" }, { "name": "glycerophospholipid catabolic process", "id": "GO:0046475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046475", "evidence": [ { "database": "UniProtKB", "id": "E1BJ80", "url": "https://www.uniprot.org/uniprotkb/E1BJ80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BJ80", "url": "https://www.uniprot.org/uniprotkb/E1BJ80" } ], "pmid": "" }, { "name": "phosphatidylcholine lysophospholipase activity", "id": "GO:0004622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004622", "evidence": [ { "database": "UniProtKB", "id": "E1BJ80", "url": "https://www.uniprot.org/uniprotkb/E1BJ80" } ], "pmid": "" }, { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "E1BJ80", "url": "https://www.uniprot.org/uniprotkb/E1BJ80" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1BJ80", "url": "https://www.uniprot.org/uniprotkb/E1BJ80" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BJ80", "url": "https://www.uniprot.org/uniprotkb/E1BJ80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "41143", "name": "", "equation": "1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphate + choline + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4K5-1" ], "evidence": [ { "id": "41143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41143" } ] }, { "id": "45544", "name": "", "equation": "N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S8W1-1", "Q58CN9-1" ], "evidence": [ { "id": "45544", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45544" } ] }, { "id": "53168", "name": "", "equation": "N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-hexadecanoylethanolamine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "53168", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53168" } ] }, { "id": "53184", "name": "", "equation": "1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O = 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + N-hexadecanoylethanolamine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3T0T0-1" ], "evidence": [ { "id": "53184", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53184" } ] }, { "id": "56460", "name": "", "equation": "N,1-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-(9Z-octadecenoyl) ethanolamine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "56460", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56460" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9S8W1", "gene_name": "NAPEPLD", "activity": [ { "ec_number": "3.1.4.54", "activity": "an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = an N-acylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphate + H(+).", "evidence": [ { "id": "A0AAA9S8W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8W1" } ] }, { "ec_number": "3.1.4.54", "activity": "", "evidence": [ { "id": "A0AAA9S8W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8W1" } ] } ] }, { "uniprot_ac": "A1A4K5", "gene_name": "ENPP2", "activity": [ { "ec_number": "3.1.4.39", "activity": "a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + ethanolamine + H(+).", "evidence": [ { "id": "A1A4K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4K5" } ] }, { "ec_number": "3.1.4.4", "activity": "a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + ethanolamine + H(+).", "evidence": [ { "id": "A1A4K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4K5" } ] }, { "ec_number": "3.1.4.39", "activity": "", "evidence": [ { "id": "A1A4K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4K5" } ] }, { "ec_number": "3.1.4.4", "activity": "", "evidence": [ { "id": "A1A4K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4K5" } ] } ] }, { "uniprot_ac": "Q3T0T0", "gene_name": "GDE1", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "Q3T0T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0T0" } ] }, { "ec_number": "3.1.4.44", "activity": "sn-glycero-3-phospho-1D-myo-inositol + H2O = 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Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015327147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015327147", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BJ94", "url": "https://www.uniprot.org/uniprotkb/E1BJ94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ94-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSNTKMKITRCGKISLCILTMVIAILVIGLIVCFVTYGKTYFYHHISFKVNNIDYDSKFAKPYSQEYTDLNNKIISLINETFHGSRLRRQYVTSQVVQVSQAKGKVIIHIVLKFKSYYTNTSAKFRDKIETILRQKLNGKTGSLCIDSSSFRFSDIAKPMAENFLHTCCGHRKITRSGNKIAGGMDAEEGEWPWQASLQQKNVHRCGATLISNSWLVTAAHCFLKARDPKQWNVSFGLLLSDPQIQRSVKDIIIHENYHYPSHKNDIAVVRLSSPVLYTSNIRRACLPETSYAFPSNSDVVVTGWGTLKTDGTSPNILQKGLVKIIDSKICNRKVVYDGAITPGMLCAGFLEGSVDACQGDSGGPLVGEDYKGTWFLAGIVSWGDECALPNKPGVYTRVTHYRDWIMSKTGL", "length": 413, "header": "tr|E1BJ94-1|E1BJ94_BOVIN Isoform 1 of Transmembrane protease serine OS=Bos taurus OX=9913 GN=LOC100140490 PE=3 SV=2 CANONICAL=E1BJ94-1" }, "isoforms": [ { "isoform_ac": "E1BJ94-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ94/entry#E1BJ94-1", "sequence": { "sequence": "MDSNTKMKITRCGKISLCILTMVIAILVIGLIVCFVTYGKTYFYHHISFKVNNIDYDSKFAKPYSQEYTDLNNKIISLINETFHGSRLRRQYVTSQVVQVSQAKGKVIIHIVLKFKSYYTNTSAKFRDKIETILRQKLNGKTGSLCIDSSSFRFSDIAKPMAENFLHTCCGHRKITRSGNKIAGGMDAEEGEWPWQASLQQKNVHRCGATLISNSWLVTAAHCFLKARDPKQWNVSFGLLLSDPQIQRSVKDIIIHENYHYPSHKNDIAVVRLSSPVLYTSNIRRACLPETSYAFPSNSDVVVTGWGTLKTDGTSPNILQKGLVKIIDSKICNRKVVYDGAITPGMLCAGFLEGSVDACQGDSGGPLVGEDYKGTWFLAGIVSWGDECALPNKPGVYTRVTHYRDWIMSKTGL", "length": 413, "header": "tr|E1BJ94-1|E1BJ94_BOVIN Isoform 1 of Transmembrane protease serine OS=Bos taurus OX=9913 GN=LOC100140490 PE=3 SV=2 CANONICAL=E1BJ94-1" }, "locus": { "chromosome": "6", "start_pos": 83518335, "end_pos": 83456630, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052687.3", "url": "https://www.ensembl.org/id/ENSBTAT00000052687.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050450.2", "url": "https://www.ensembl.org/id/ENSBTAP00000050450.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100140490", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140490", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TFD6-1", "protein_name": "Transmembrane protease serine", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLTGWKQIALGILMMVIAAVVIGLIVYFVTYGKTPFYYHISFKVNNIDYDSKFEKPYSQEYMDLNEKIESLINETFHGSRLRRQYIRSHVVQVSRAKGKVIIHAVLKFKSCYINNTAKFRDKIKTILQQKLKGKTGSLSIESSSFRFSDITMPIAENLLHTCCGQRTITPSGNKIAGGMDAQEGEWPWQASLQQNNVHRCGATLISNSWLVTAAHCFIKVRNPKEWNVSFGLLLSDPQIQRSVKDIIIHENYHYPAHDNDIAVVHLSSPVLYTSSIRRACLPEATYAFPPNSNVVVTGWGTLKSDGTSPNILQKGLVKIIDNKTCSSKMVYDGAITPGMLCAGFLKGRVDACQGDSGGPLVGADYKGTWFLAGIVSWGDECALPNKPGVYTRVTYYRDWIMSKTGL", "length": 407 }, "evidence": [ { "id": "E1BJ94", "url": "https://omabrowser.org/oma/group/E1BJ94/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZM18-1", "protein_name": "Transmembrane protease serine", "gene_name": "Tmprss11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARGQPRRSEEPWTALRNRTECKTKIKLTKCGKITLGILTAVIAAVVIGLIAYFAACGKTPFYYHVSFKVNNIDYDSKFAKPYSQEYMDLNKRIVSLMNETFHESKLRKQYVKAHTVQVSKAKGKVVIHGVLKFKSCYKNNVEKFWDSVETILYQKLKSQTRLLIDSSSFKFSDIAMPIAEDLLNTCCGRRTITPGGHKVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCFVRSANPKDWKVSFGFLLSKPQAQRAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYENNIRRACLPEATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGRVKIIDNKTCNSGKAYGGVITPGMLCAGFLEGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWISSKTGL", "length": 431 }, "evidence": [ { "id": "E1BJ94", "url": "https://omabrowser.org/oma/group/E1BJ94/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1JRP2-1", "protein_name": "Transmembrane protease serine 11C", "gene_name": "Tmprss11c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARGQPRRSEEQWTALQNRTECKTKIKLTRCGKITLGILTAVLAAVLIGLIAYFAACGKDSFYYHVSFKVNNIDYDSKFAKPYSQEYMDLNKRIVSLMNETFHESKLRKQYVKAHTVQVSKAKGKVVIHAVLKFKACYRNNVEKYWESVETTLYQKLKGQTGLLIDSSSFKFSDIAMPIAEDLLNTCCGRRTIIHRGHKVAGGQDAEEGEWPWQASLQQNSVHRCGATLISNYWLITAAHCFIRAANPKDWKVSFGFLLSKPQAPRAVKNIIIHENYSYPAHDNDIAVVRLSSPVLYESNIRRACLPEATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGKVKIIDNKTCNSGKAYGGMITPGMMCAGFLKGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTYYRDWITSKTGL", "length": 431 }, "evidence": [ { "id": "E1BJ94", "url": "https://omabrowser.org/oma/group/E1BJ94/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "E1BJ94", "url": "https://www.uniprot.org/uniprotkb/E1BJ94" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "E1BJ94", "url": "https://www.uniprot.org/uniprotkb/E1BJ94" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BJ94", "url": "https://www.uniprot.org/uniprotkb/E1BJ94" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BJ94", "url": "https://www.uniprot.org/uniprotkb/E1BJ94" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "E1BJ94", "url": "https://www.uniprot.org/uniprotkb/E1BJ94" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "E1BJ94", "url": "https://www.uniprot.org/uniprotkb/E1BJ94" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "E1BJ94", "url": "https://www.uniprot.org/uniprotkb/E1BJ94" } ], "pmid": "" }, { "name": "self proteolysis", "id": "GO:0097264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097264", "evidence": [ { "database": "UniProtKB", "id": "E1BJ94", "url": "https://www.uniprot.org/uniprotkb/E1BJ94" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJ94-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 413, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJ94-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJ94" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ94" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 182, "end_pos": 412, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ94" }, { "id": "PS50024", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50024" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEA", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 159, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJC0-1", "uniprot_ac": "E1BJC0", "uniprot_id": "E1BJC0_BOVIN", "mass": { "chemical_mass": 54717.0, "monoisotopic_mass": 54717.0 }, "refseq": { "ac": "XP_002689710", "name": "carnosine N-methyltransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689710" }, "gene_names": [ { "name": "CARNMT1", "type": "recommended", "evidence": [ { "id": "E1BJC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJC0" } ] }, { "name": "CARNMT1", "type": "synonym", "evidence": [ { "id": "XP_002689710", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689710" } ] } ], "protein_names": [ { "name": "Carnosine N-methyltransferase", "type": "recommended", "evidence": [ { "id": "E1BJC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJC0/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.22", "type": "synonym", "evidence": [ { "id": "E1BJC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJC0/entry#names_and_taxonomy" } ] }, { "name": "carnosine N-methyltransferase", "type": "synonym", "evidence": [ { "id": "XP_002689710", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689710" } ] } ], "function": [ { "annotation": "N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).", "evidence": [ { "database": "UniProtKB", "id": "E1BJC0", "url": "https://www.uniprot.org/uniprotkb/E1BJC0#function" }, { "database": "UniProtKB", "id": "ARBA00054322", "url": "https://www.uniprot.org/uniprotkb/ARBA00054322#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJC0", "url": "https://www.uniprot.org/uniprotkb/E1BJC0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CARNMT1", "url": "https://www.uniprot.org/uniprotkb/E1BJC0", "locus": { "chromosome": "8", "start_pos": 51057246, "end_pos": 51098105, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008204", "url": "https://www.ensembl.org/id/ENSBTAG00000008204" } ] } } ], "crossref": [ { "id": "E1BJC0", "url": "https://alphafold.ebi.ac.uk/entry/E1BJC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008204", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008204", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538441", "url": "https://www.ncbi.nlm.nih.gov/gene/538441", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538441", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538441", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GSMSMCA", "url": "https://omabrowser.org/oma/group/GSMSMCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJC0", "url": "https://www.orthodb.org/?gene=E1BJC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12303", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12303", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12303:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12303:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07942", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07942", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-70921", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70921", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002689710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689710", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BJC0", "url": "https://www.uniprot.org/uniprotkb/E1BJC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJC0-1", "url": "https://www.uniprot.org/uniprotkb/E1BJC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRRCRFGSSEDLAEPGADGGLRAAGAERAASRGHVRGGRRLEEGRAATTTLSVAARRKRARLRAAAAMQRRRRPPPPASQLPEGCGGGGGGRGGGGGSEEVEVQFSAGRLGSAAAVSAAAAAAAARSTEEEEERLEREHFWKIINAFRYYGTSMHERVHRTERQFRSLPANQQKLLPQFLLHLDKIRKCVDHNQEILLTIVNDCIHMFENKEYGEDGNGKIMPASTFDMDKLKSTLKQFVRDWSETGKAERDACYQPIIKEILKNFPKEKWDPSKVNILVPGAGLGRLAWEIAMLGYACQGNEWSFFMLFSSNFVLNRCSEINKYKLYPWIHQFSNNRRSADQIRPIFFPDVDPHSLPPGSNFSMTAGDFQEIYSECNTWDCIATCFFIDTAHNVIDYIDTIWKILKPGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFQLEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ", "length": 484, "header": "tr|E1BJC0-1|E1BJC0_BOVIN Isoform 1 of Carnosine N-methyltransferase OS=Bos taurus OX=9913 GN=CARNMT1 PE=3 SV=2 CANONICAL=E1BJC0-1" }, "isoforms": [ { "isoform_ac": "E1BJC0-1", "url": "https://www.uniprot.org/uniprotkb/E1BJC0/entry#E1BJC0-1", "sequence": { "sequence": "MRRRCRFGSSEDLAEPGADGGLRAAGAERAASRGHVRGGRRLEEGRAATTTLSVAARRKRARLRAAAAMQRRRRPPPPASQLPEGCGGGGGGRGGGGGSEEVEVQFSAGRLGSAAAVSAAAAAAAARSTEEEEERLEREHFWKIINAFRYYGTSMHERVHRTERQFRSLPANQQKLLPQFLLHLDKIRKCVDHNQEILLTIVNDCIHMFENKEYGEDGNGKIMPASTFDMDKLKSTLKQFVRDWSETGKAERDACYQPIIKEILKNFPKEKWDPSKVNILVPGAGLGRLAWEIAMLGYACQGNEWSFFMLFSSNFVLNRCSEINKYKLYPWIHQFSNNRRSADQIRPIFFPDVDPHSLPPGSNFSMTAGDFQEIYSECNTWDCIATCFFIDTAHNVIDYIDTIWKILKPGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFQLEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ", "length": 484, "header": "tr|E1BJC0-1|E1BJC0_BOVIN Isoform 1 of Carnosine N-methyltransferase OS=Bos taurus OX=9913 GN=CARNMT1 PE=3 SV=2 CANONICAL=E1BJC0-1" }, "locus": { "chromosome": "8", "start_pos": 51097975, "end_pos": 51058250, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010790.6", "url": "https://www.ensembl.org/id/ENSBTAT00000010790.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010790.5", "url": "https://www.ensembl.org/id/ENSBTAP00000010790.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:538441", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538441", "resource": "KEGG Pathway" }, { "id": "R-BTA-70921", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70921", "resource": "Reactome", "description": "Histidine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N9S8-1", "protein_name": "Protein-L-histidine N-pros-methyltransferase CARNMT1", "gene_name": "CARNMT1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAACAVSREAQPALPPPPRGDRDPPAKAMRRGLRRGREEEQDQERLPWPAESGGGDPEGEQEAWRSGERRRRQPQEPRALAAAARVEEEAEEERMEREHFRRIINAFRYYGTNMHERVNRTERQFKSLPANQQSLLPQFLPHLDKIRKCIDHNQEILQTIVNDCVHMFENKEYGEDGGGKITPASTFDMDKLKSTLKQFVRDWSEEGKPERDSCYQPIISEIVKNFPKERWDFSKVNILVPGAGLGRLAWEIAMLGYACQGNEWSLFMLFSSNFVLNRCSEVNSCKLYPWIHQFSNNKRSADQIRPIYFPDVDPHSLPSGSNFSMTAGDFQEIYSECNTWDCIATCFFIDTAHNVIDYIDTIWKILKPGGIWINVGPLLYHFENLANELSIELSYEDIKNVILQYGFHIEVEKESVLSTYTVNELSMMKYYYECVLFVVRKPEEKCFE", "length": 449 }, "evidence": [ { "id": "E1BJC0", "url": "https://omabrowser.org/oma/group/E1BJC0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q80UY1-1", "protein_name": "Protein-L-histidine N-pros-methyltransferase CARNMT1", "gene_name": "Carnmt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRRQRAPPASQPAQDGGRSEDVEVQFSAGRLGSAAPAGPPARGTAEDEERLEREHFWKVINAFRYYGTSMHERVNRTERQFRSLPENQQKLLPQFPLHLDKIRKCIDHNQEILLTIVNDCIHMFENKEYGEDANGKIMPASTFDMDKLKSTLKQFVRDWSETGKAERDACYKPIIKEIIKNFPKERWDPSKVNILVPGAGLGRLAWEVAMLGYACQGNEWSFFMLFSSNFVLNRCSEINKYKLYPWIHQFSNNRRSADQIRPILFPDVDPHSLPPGSNFSMTAGDFQEIYSECNAWDCIATCFFIDTAHNVIDYIDTIWRILKPGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFQLEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ", "length": 400 }, "evidence": [ { "id": "E1BJC0", "url": "https://omabrowser.org/oma/group/E1BJC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N4J0-1", "protein_name": "Protein-L-histidine N-pros-methyltransferase CARNMT1", "gene_name": "CARNMT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQRRRRPPPPTSRLPEGCGGGGGGSEEVEVQFSAGRWGSAAAVSAAAAAATRSTEEEEERLEREHFWKIINAFRYYGTSMHERVNRTERQFRSLPANQQKLLPQFLLHLDKIRKCIDHNQEILLTIVNDCIHMFENKEYGEDGNGKIMPASTFDMDKLKSTLKQFVRDWSETGKAERDACYQPIIKEILKNFPKERWDPSKVNILVPGAGLGRLAWEIAMLGYACQGNEWSFFMLFSSNFVLNRCSEINKYKLYPWIHQFSNNRRSADQIRPIFFPDVDPHSLPPGSNFSMTAGDFQEIYSECNTWDCIATCFFIDTAHNVIDYIDTIWKILKPGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFKVEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ", "length": 409 }, "evidence": [ { "id": "E1BJC0", "url": "https://omabrowser.org/oma/group/E1BJC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9I7X6-2", "protein_name": "Carnosine N-methyltransferase unmet", "gene_name": "unmet", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSMDCATFPMHPKMDEQLARTFVINEEEEEKHIQKVQNAFLYYGPYACQRLKRSMDYLNSLSGEDQIMLAKYRGHLECVRTCIDRNQAVIREILRGRVLYPTDEATGDPSEFDEPPPNVRHGDMDQIDIPFDEADVEPLKILKAQSTLKLIARDWSTEGALEREQSYKPIIDSIVAYFKHSDFELKDIKILVPGAGLGRLTYELACLGYSCEGNEFSYFMLIASNFVLNLCDNENKYVLYPWVHQYVNNLRREDQVAPVRFPDVCPLKNPPKGHFEIAAGDFLEVYKTPNAYNCVATCFFIDCANNVIDFIRTIYKILVPGGIWVNLGPLLYHFSDVSGQNSIEPAFEDLCIIMESVGFVIEKSRTGIRTKYAQNPSSMKQSEYQSLFWVCRKPDLFEEQRGKRKASREPHDLIVREDSEEEGEQQPERNETEEKQQLKPLATANCETEIKEQPS", "length": 456 }, "evidence": [ { "id": "E1BJC0", "url": "https://omabrowser.org/oma/group/E1BJC0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BJC0", "url": "https://www.uniprot.org/uniprotkb/E1BJC0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BJC0", "url": "https://www.uniprot.org/uniprotkb/E1BJC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "E1BJC0", "url": "https://www.uniprot.org/uniprotkb/E1BJC0" } ], "pmid": "" }, { "name": "carnosine N-methyltransferase activity", "id": "GO:0030735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030735", "evidence": [ { "database": "UniProtKB", "id": "E1BJC0", "url": "https://www.uniprot.org/uniprotkb/E1BJC0" } ], "pmid": "" }, { "name": "protein-L-histidine N-pros-methyltransferase activity", "id": "GO:0106370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106370", "evidence": [ { "database": "UniProtKB", "id": "E1BJC0", "url": "https://www.uniprot.org/uniprotkb/E1BJC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "E1BJC0", "url": "https://www.uniprot.org/uniprotkb/E1BJC0" } ], "pmid": "" }, { "name": "carnosine metabolic process", "id": "GO:0035498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035498", "evidence": [ { "database": "UniProtKB", "id": "E1BJC0", "url": "https://www.uniprot.org/uniprotkb/E1BJC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-8876789", "name": "CARNMT1 methylates CARN to Anserine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-6786250" ], "output_participant_list": [ "R-ALL-8876775" ], "enzyme_list": [ "E1BJC0-1" ], "evidence": [ { "id": "R-BTA-8876789", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876789" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6786250", "participant_name": "CARN [cytosol]", "crossref": [ { "id": "57485", "database": "ChEBI", "url": "" }, { "id": "ZINC000002040854", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-8876775", "participant_name": "Anserine [cytosol]", "crossref": [ { "id": "58445", "database": "ChEBI", "url": "" }, { "id": "ZINC000001532910", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BJC0", "gene_name": "CARNMT1", "activity": [ { "ec_number": "2.1.1.22", "activity": "carnosine + S-adenosyl-L-methionine = anserine + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1BJC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJC0" } ] }, { "ec_number": "2.1.1.22", "activity": "", "evidence": [ { "id": "E1BJC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJC0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJC0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 484, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJC0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJC0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.22", "ec_name": "carnosine + S-adenosyl-L-methionine = anserine + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "2.1.1.22", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.22" }, { "id": "2.1.1.22", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.22" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 363, "end_pos": 365 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJE3-1", "uniprot_ac": "E1BJE3", "uniprot_id": "E1BJE3_BOVIN", "mass": { "chemical_mass": 57500.0, "monoisotopic_mass": 57500.0 }, "refseq": {}, "gene_names": [ { "name": "LOC516378", "type": "recommended", "evidence": [ { "id": "E1BJE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJE3" } ] } ], "protein_names": [ { "name": "alkaline phosphatase", "type": "recommended", "evidence": [ { "id": "E1BJE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJE3/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.1", "type": "synonym", "evidence": [ { "id": "E1BJE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJE3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJE3", "url": "https://www.uniprot.org/uniprotkb/E1BJE3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC516378", "url": "https://www.uniprot.org/uniprotkb/E1BJE3", "locus": {} } ], "crossref": [ { "id": "E1BJE3", "url": "https://alphafold.ebi.ac.uk/entry/E1BJE3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016748", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016748", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516378", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NMPCSAR", "url": "https://omabrowser.org/oma/group/NMPCSAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJE3", "url": "https://www.orthodb.org/?gene=E1BJE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11596", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11596", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11596:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11596:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00245", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00245", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1483166", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8935690", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8935690", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BJE3", "url": "https://www.uniprot.org/uniprotkb/E1BJE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJE3-1", "url": "https://www.uniprot.org/uniprotkb/E1BJE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGACVLLLLGLRLQLSLGLVPVEEEDPAFWNRQAAQALDVAKKLQPIQTAAKNVILFLGDGMGVSTVTAARILKGQMAGKPGPETPLAMDQFPYLALSKTYNVDRDVPDSAGTTTAYLCGVKTRMKVIGVSAAAQFNQCNTTYGNEVTSVMNRAKKAGKSVGVVTTTTVQHASPAGAYAHTVNRNWYSDANMPAEAKREGCQDIATQLVYNMDIDVILGGGRIYMFPEGTPDPEYPGNTKQNGVRKDKRNLVQEWQAKHQGAQYVWNRTALLQAANDSSVTHLMGLFEPGDMTYDIHRDHIKDPSLEEMTEAAVRVLSRNPRGFFLFVEGGRIDHGHHESIAYRALTEAVMFDNAIAKASQLTSEADTLTLVTADHSHVFTFGGYPLRGTSIFGLADGKAKDGKSYTTLLYGNGPGHRLVMGSRPDVNEKESMDPEYQQQSAVPLWGETHAGEDVAVFARGPWAHLVHGVQEQTFVAHVMAFAACVEPYTTDCHPHPHSGPSDTAHRQPPSSLALLAGALLLLLVPTLH", "length": 530, "header": "tr|E1BJE3-1|E1BJE3_BOVIN Isoform 1 of alkaline phosphatase OS=Bos taurus OX=9913 GN=LOC516378 PE=3 SV=2 CANONICAL=E1BJE3-1" }, "isoforms": [ { "isoform_ac": "E1BJE3-1", "url": "https://www.uniprot.org/uniprotkb/E1BJE3/entry#E1BJE3-1", "sequence": { "sequence": "MQGACVLLLLGLRLQLSLGLVPVEEEDPAFWNRQAAQALDVAKKLQPIQTAAKNVILFLGDGMGVSTVTAARILKGQMAGKPGPETPLAMDQFPYLALSKTYNVDRDVPDSAGTTTAYLCGVKTRMKVIGVSAAAQFNQCNTTYGNEVTSVMNRAKKAGKSVGVVTTTTVQHASPAGAYAHTVNRNWYSDANMPAEAKREGCQDIATQLVYNMDIDVILGGGRIYMFPEGTPDPEYPGNTKQNGVRKDKRNLVQEWQAKHQGAQYVWNRTALLQAANDSSVTHLMGLFEPGDMTYDIHRDHIKDPSLEEMTEAAVRVLSRNPRGFFLFVEGGRIDHGHHESIAYRALTEAVMFDNAIAKASQLTSEADTLTLVTADHSHVFTFGGYPLRGTSIFGLADGKAKDGKSYTTLLYGNGPGHRLVMGSRPDVNEKESMDPEYQQQSAVPLWGETHAGEDVAVFARGPWAHLVHGVQEQTFVAHVMAFAACVEPYTTDCHPHPHSGPSDTAHRQPPSSLALLAGALLLLLVPTLH", "length": 530, "header": "tr|E1BJE3-1|E1BJE3_BOVIN Isoform 1 of alkaline phosphatase OS=Bos taurus OX=9913 GN=LOC516378 PE=3 SV=2 CANONICAL=E1BJE3-1" }, "locus": { "chromosome": "2", "start_pos": 120041492, "end_pos": 120038513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022731.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022731.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022731.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022731.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:516378", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516378", "resource": "KEGG Pathway" }, { "id": "R-BTA-1483166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483166", "resource": "Reactome", "description": "Synthesis of PA" }, { "id": "R-BTA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" }, { "id": "R-BTA-8935690", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8935690", "resource": "Reactome", "description": "Digestion" } ], "orthologs": [ { "uniprot_canonical_ac": "P05187-1", "protein_name": "Alkaline phosphatase, placental type", "gene_name": "ALPP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGPCMLLLLLLLGLRLQLSLGIIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPAGTTDAAHPGRSVVPALLPLLAGTLLLLETATAP", "length": 535 }, "evidence": [ { "id": "E1BJE3", "url": "https://omabrowser.org/oma/group/E1BJE3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alkaline phosphatase activity", "id": "GO:0004035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004035", "evidence": [ { "database": "UniProtKB", "id": "E1BJE3", "url": "https://www.uniprot.org/uniprotkb/E1BJE3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BJE3", "url": "https://www.uniprot.org/uniprotkb/E1BJE3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BJE3", "url": "https://www.uniprot.org/uniprotkb/E1BJE3" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "E1BJE3", "url": "https://www.uniprot.org/uniprotkb/E1BJE3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-8878780" ], "output_participant_list": [ "R-ALL-8878776" ], "enzyme_list": [ "E1BJE3-1" ], "evidence": [ { "id": "R-BTA-8878787", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8878787" } ] }, { "id": "R-BTA-8940388", "name": "GPLD1 hydrolyses GPI-anchors from proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-2197633" ], "enzyme_list": [ "F1MLP3-1", "A0A3Q1LSG5-1", "P09487-1", "E1B735-1", "A0AAA9S718-1", "F1MNM2-1", "F1MPH8-1", "A0A140T891-1", "A0A3Q1MCB1-1", "E1BJE3-1" ], "evidence": [ { "id": "R-BTA-8940388", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8940388" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2197633", "participant_name": "PI [extracellular region]", "crossref": [ { "id": "57880", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-8878776", "participant_name": "Alcohol [extracellular region]", "crossref": [ { "id": "30879", "database": "ChEBI", "url": "" }, { "id": "C00069", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-8878780", "participant_name": "phosphate monoester [extracellular region]", "crossref": [ { "id": "7794", "database": "ChEBI", "url": "" }, { "id": "Orthophosphoric-Monoesters", "database": "AraCyc", "url": "" }, { "id": "C01153", "database": "KEGG Gene", "url": "" }, { "id": "C01153", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T891", "gene_name": "VNN1", "activity": [ { "ec_number": "3.5.1.92", "activity": "(R)-pantetheine + H2O = cysteamine + (R)-pantothenate.", "evidence": [ { "id": "A0A140T891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T891" } ] }, { "ec_number": "3.5.1.92", "activity": "", "evidence": [ { "id": "A0A140T891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T891" } ] } ] }, { "uniprot_ac": "A0A3Q1LSG5", "gene_name": "LOC100125266", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1LSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "A0A3Q1LSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ] } ] }, { "uniprot_ac": "A0A3Q1MCB1", "gene_name": "", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1MCB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCB1" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "A0A3Q1MCB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCB1" } ] } ] }, { "uniprot_ac": "A0AAA9S718", "gene_name": "SMCO3", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0AAA9S718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S718" } ] }, { 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Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells.", "evidence": [ { "database": "UniProtKB", "id": "E1BJE6", "url": "https://www.uniprot.org/uniprotkb/E1BJE6#function" }, { "database": "UniProtKB", "id": "ARBA00037402", "url": "https://www.uniprot.org/uniprotkb/ARBA00037402#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJE6", "url": "https://www.uniprot.org/uniprotkb/E1BJE6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC25A28", "url": "https://www.uniprot.org/uniprotkb/E1BJE6", "locus": { "chromosome": "26", "start_pos": 20596417, "end_pos": 20607094, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012107", "url": 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"tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELEGRSAGGVAGGPAAGPGRSPGESALLDGWLQRGVGRGAGGGEAGAYQTPVRLDPESGPEYEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIANGIEPPRAGPHFPNSLGLAAVSASQPRMVWSGSLGLGAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFNPQRRYNPSSHVLCGACAGAVAAAATTPLDVCKTLLNTQESLALSSNITGHITGMANAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEEWRAGK", "length": 399 }, "evidence": [ { "id": "E1BJE6", "url": "https://omabrowser.org/oma/group/E1BJE6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7T292-1", "protein_name": "Mitoferrin-2", "gene_name": "slc25a28", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"MELEGRSAGGVAGGPAAGPGRSPGESALLDGWLQRGVGRGAGGGEAGAYQPPVRLDPESGPEYEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIMRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIANGAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFNPQRRYNPSSHVLCGACAGAVAAAATTPLDVCKTLLNTQESLALNSNITGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEEWRAGK", "length": 364 }, "evidence": [ { "id": "E1BJE6", "url": "https://omabrowser.org/oma/group/E1BJE6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96A46-1", "protein_name": "Mitoferrin-2", "gene_name": "SLC25A28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515209", "resource": "KEGG Pathway" }, { "id": "R-BTA-419408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-419408", "resource": "Reactome", "description": "Lysosphingolipid and LPA receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N481-1", "protein_name": "Phospholipid phosphatase-related protein type 1", "gene_name": "Plppr1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVGNNTQRSYSIIPCFIFVELVIMAGTVLLAYYFECTDTFQVHIQGFFCQDGDLMKPYPGTEEESFITPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIAEEKTILTGECCYLNPLLRRIIRFIGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCQPNYTSTDCRAHHQFITNGNICTGDLEVIEQARRSFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMCVVHNFKGTQGSPSKPKPEDPRGVPLMAFPRIESPLETLSAQNHSASMTEVT", "length": 325 }, "evidence": [ { "id": "E1BJF3", "url": "https://omabrowser.org/oma/group/E1BJF3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6WAY2-1", "protein_name": "Phospholipid phosphatase-related protein type 1", "gene_name": "Plppr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVENNTQRSYSIIPCFIFVELVIMAGTVLLAYYFECTDTFQVHIQGFFCQDGDLMKPYPGTEEESFISPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIAEEKMILTGDCCYLSPLLRRIVRFIGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCQPNYTSTDCRAHHQFINNGNICTGDLEVIEKARRSFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPVLCLGDLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMCVVHNFKGTQGSASKPKPEDPRGVPLMAFPRIESPLETLSAQNHSASMTEVT", "length": 325 }, "evidence": [ { "id": "E1BJF3", "url": "https://omabrowser.org/oma/group/E1BJF3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BFZ2-1", "protein_name": "Phospholipid phosphatase-related protein type 1", "gene_name": "Plppr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJF3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJF3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF3" }, { "id": "SM00014", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidic acid phosphatase type 2/haloperoxidase", "eco_id": "ECO_0000259", "start_pos": 128, "end_pos": 272, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJF6-1", "uniprot_ac": "E1BJF6", "uniprot_id": "E1BJF6_BOVIN", "mass": { "chemical_mass": 140839.0, "monoisotopic_mass": 140839.0 }, "refseq": {}, "gene_names": [ { "name": "SYMPK", "type": "recommended", "evidence": [ { "id": "E1BJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" } ] } ], "protein_names": [ { "name": "Symplekin", "type": "recommended", "evidence": [ { "id": "E1BJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing. Specific component of the tight junction (TJ) plaque, but might not be an exclusively junctional component. May have a house-keeping rule. Is involved in pre-mRNA polyadenylation. Enhances SSU72 phosphatase activity.", "evidence": [ { "database": "UniProtKB", "id": "E1BJF6", "url": "https://www.uniprot.org/uniprotkb/E1BJF6#function" }, { "database": "UniProtKB", "id": "ARBA00053251", "url": "https://www.uniprot.org/uniprotkb/ARBA00053251#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJF6", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SYMPK", "url": "https://www.uniprot.org/uniprotkb/E1BJF6", "locus": { "chromosome": "18", "start_pos": 53350775, "end_pos": 53380309, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012101", "url": "https://www.ensembl.org/id/ENSBTAG00000012101" } ] } } ], "crossref": [ { "id": "E1BJF6", "url": "https://alphafold.ebi.ac.uk/entry/E1BJF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012101", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012101", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NVRYGIM", "url": "https://omabrowser.org/oma/group/NVRYGIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJF6", "url": "https://www.orthodb.org/?gene=E1BJF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15245:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15245:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11935", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11935", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12295", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12295", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73856", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73856", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-77595", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77595", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BJF6", "url": "https://www.uniprot.org/uniprotkb/E1BJF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJF6-1", "url": "https://www.uniprot.org/uniprotkb/E1BJF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASSGDSVTRRSVASQFFTQEEGPGIDGMTTSERVVDLLNQAALITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVISELQEACWDMVSAMAGDIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEVPRRQEHDISLDRIPRDHPYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLNVLKHPASLEFQAQITTLLVDLGTPQVEIARNMPSGKDARKRPRDDSDSTLKKMKLEPNLGEDDEDKDLEPGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPEAMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKPESVLIKRRLPAQGQAISVVGSLSSMSSLEEEAPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSDVLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQVRIKILASLVTQFDSGLKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGVKGALDKYEDCLIRLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVIRKYCEDESRTYLGMSTLRDLIFKRPSRQFQYLHVLLDLSSHEKDKVRSQALLFIKRMYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQHGEGNSALSPLNPGELLIALHNIDSAKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMAILEASGKQEPETKEAPAGPLEEDDLEPLALAPPPAPRPPQDLIGLRLAQEKALKRQLEEEQKLKPGGLGGPSSSSSSSSARPGPPQPEEAIDFREEGPECETPAIFISMDDDSGLTEAALLDSSLEGPLPKETAAGGLLSKEERSPQPLTAAGEDTVQTPSPATEEVGEPETKGNS", "length": 1271, "header": "tr|E1BJF6-1|E1BJF6_BOVIN Isoform 1 of Symplekin OS=Bos taurus OX=9913 GN=SYMPK PE=3 SV=2 CANONICAL=E1BJF6-1" }, "isoforms": [ { "isoform_ac": "E1BJF6-1", "url": "https://www.uniprot.org/uniprotkb/E1BJF6/entry#E1BJF6-1", "sequence": { "sequence": "MAASSGDSVTRRSVASQFFTQEEGPGIDGMTTSERVVDLLNQAALITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVISELQEACWDMVSAMAGDIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEVPRRQEHDISLDRIPRDHPYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLNVLKHPASLEFQAQITTLLVDLGTPQVEIARNMPSGKDARKRPRDDSDSTLKKMKLEPNLGEDDEDKDLEPGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPEAMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKPESVLIKRRLPAQGQAISVVGSLSSMSSLEEEAPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSDVLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQVRIKILASLVTQFDSGLKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGVKGALDKYEDCLIRLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVIRKYCEDESRTYLGMSTLRDLIFKRPSRQFQYLHVLLDLSSHEKDKVRSQALLFIKRMYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQHGEGNSALSPLNPGELLIALHNIDSAKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMAILEASGKQEPETKEAPAGPLEEDDLEPLALAPPPAPRPPQDLIGLRLAQEKALKRQLEEEQKLKPGGLGGPSSSSSSSSARPGPPQPEEAIDFREEGPECETPAIFISMDDDSGLTEAALLDSSLEGPLPKETAAGGLLSKEERSPQPLTAAGEDTVQTPSPATEEVGEPETKGNS", "length": 1271, "header": "tr|E1BJF6-1|E1BJF6_BOVIN Isoform 1 of Symplekin OS=Bos taurus OX=9913 GN=SYMPK PE=3 SV=2 CANONICAL=E1BJF6-1" }, "locus": { "chromosome": "18", "start_pos": 53380027, "end_pos": 53350897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016048.6", "url": "https://www.ensembl.org/id/ENSBTAT00000016048.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016048.6", "url": "https://www.ensembl.org/id/ENSBTAP00000016048.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless Transcript" }, { "id": "R-BTA-73856", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73856", "resource": "Reactome", "description": "RNA Polymerase II Transcription Termination" }, { "id": "R-BTA-77595", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77595", "resource": "Reactome", "description": "Processing of Intronless Pre-mRNAs" }, { "id": "R-BTA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4I9D6-1", "protein_name": "Symplekin isoform X1", "gene_name": "sympk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMAGEQASGASSQIHSNEEDKAFDMTTSERVVDLLNQAALISTEEKLIVLKQVQELVINKDPSLLDNFLDEIIAFQTDKSIEVRKFVIGFIEEACKRDNELLLRLIANLNMLMRDESVNVVKKAILTLTQLYKVALQWLVRTKSVTDMQEACWDMVTQMKGDVLALLDSDNDGVRTHAIKFTESLIITLSPRTPDSDTPKKQEGDISLDKIPKDHTYIRYDTLCEEGKTALDQLLKFMVHPAISSINLTTALGSLATLARQRPMFMSEVVQAYEMLHANLPPTLAKSQVSSVRKNLKLHLVAVLKHPSSVDFHVQISTLLQDLGMSPSEITRCTPVAVQPRKRLHHEPYVEGKRIKMEAVEDDEDKEEPAPVVTPKPSSSIGTQSAIDLTAEFLLPLLTSDNVANLVLISMVYLPEVMPASFQATYTPVESAGTDAQIKHLARLMATQMTAAGLGPGLEQCKARDEEVKEEGAAGESSSKDPLIIRKLSAVSLGQAISVVGASAAYKSPIIEEAPQIKKLPEPILPSTQLKAPGASGRKKVFKLADVVQPFSEVQIEKLANMAIKRILYSEKAIAQTGMSHVRVKLLARLVTQFEGTKKNDLLQFVLEDMRSRSELAFSLLYHEYNEYLSQEPSGCLDSYEHCLFTLLSGLQERPEQRDGLFTKIVLEAPIITDSALEVIQRYCEDESRVYLGMSTLKELIFKRPSRQYQYLNVLLNLTSHEKEKVRSTALSFIKRMYEKEHLKDCIEKFALTYMQFLVHPNPPSLLFGAGEDTEVAAPWTEETVRQCLYLYLSLLPLNHRLVHELAAVYTEAIADIKRSVLRVIEQPIRGMGMNSPDLLLLVENCPKGAETLVTRCLHILTDKVPPSPELVERVRDLYHKRVPDVRFLIPVINGLEKNEVIQALPKLIKLNPIVVKEVFNRLLGTQHSEGSSSMSPLTPGELLIALHNIDSSKCDMKSIIKATNLCFGEKNVYTSEVLAVVMQQLMEQTPLPILLMRTVIQSLTMYPRLAGFVMNILARLILKQVWKYPKVWEGFVKCCQRTKPQSYNVLLQLPPPQLASVFERCPEMREPLLQHVHSFTPHQQAHIPTSIMTVLEATNRKPEPEPQPEIQHPEVMEEREVPLPKHISVHAPVQQAEPPAPKPIVFTEPMPPQEKHHHHHQVPSRREVAEVAEPMEQEETAHVPEEDTSEAPPQQMDVSEEAPQSSPVAEKADESMDESTAGPADEAEEPVEEPEEEHAETGESSAD", "length": 1248 }, "evidence": [ { "id": "E1BJF6", "url": "https://omabrowser.org/oma/group/E1BJF6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LSH0-1", "protein_name": "Symplekin", "gene_name": "Sympk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGSGDSVTRRSVASQFFTQEEGPGIDGMTTSERVVDLLNQAALITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSTEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVISDLQEACWDMVSSMAAEIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEVPRRQEHDISLDRIPRDHPYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDSRKRPRDDTESTLKKMKLEPNLGEDDEDKDLEPGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPETMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKPESVLIKRRLSVQGQAISVVGSQSTMSPLEEEVPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSDVLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQVRIKILASLVTQFDSGFKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGPSGTLDKYEDCLICLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVIRKYCEDESRAYLGMSTLGDLIFKRPSRQFQYLHVLLDLSSHEKDRVRSQALLFIKRMYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQHGPCVVEVEKLGEWGSHLMRDIQAERGQATLRLLTATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILARLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMTILEASGKQEPEVKEAPSGSLEEDDLEPLALALAPALAPAPAPRPPQDLIGLRLAQEKALKRQLEEEQKQKPTGVGAPTSSVSSTPLVGPAARAGPTPAEEVMEYREEGPECETPAIFISMDDDSGLAETTLLDSSLEGPLPKEAAAVGPSSKDERSPQNLSHAVEEALKTSSPEAREPESKGNS", "length": 1280 }, "evidence": [ { "id": "E1BJF6", "url": "https://omabrowser.org/oma/group/E1BJF6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RM40-1", "protein_name": "Symplekin", "gene_name": "SYMPK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGSSGDSVTRRSVASQFFTQEEGPGIDGMTTSERVVDLLNQAALITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVISELQEACWDMVSAMAGDIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEVPRRQEHDISLDRIPRDHPYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDARKRPRDDSDSTLKKMKLEPNLGEDDEDKDLEPGPSGTSKASAQISGQSDTDITADFLQPLLTPDNVANLVLISMVYLPEAMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKPESVLIKRRLSAQGQAISVVGSLSSMSTLEEEAPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLCDVLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQVRIKILASLVTQFDSGLKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGAAGTLDKYEDCLIRLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVIRKYCEDESRTYLGMSTLRDLIFKRPSRQFQYLHVLLDLSSHEKDKVRSQALLFIKRMYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQHGEGNSALSPLNPGELLIALHNIDSAKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMTILEASGKQEPETKEAPAGPLEEDDLEPLALAPPPAPRPPQDLIGLRLAQEKALKRQLEEEQKLKPGGVGAPSSSSSSSSARPGPPQPEEAIDFREEGPECETPAIFISMDDDSGLTEAALLDSSLEGPLPKEAAIGLISKEERSPQTLTPALEDIVKTPSPAAEEAGEPETKGNS", "length": 1271 }, "evidence": [ { "id": "E1BJF6", "url": "https://omabrowser.org/oma/group/E1BJF6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q80X82-1", "protein_name": "Symplekin", "gene_name": "Sympk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1288 }, "evidence": [ { "id": "E1BJF6", "url": "https://omabrowser.org/oma/group/E1BJF6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MSU4-1", "protein_name": "Symplekin", "gene_name": "Sym", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDSIIGRSQFVSETANLFTDEKTATARAKVVDWCNELVIASPSTKCELLAKVQETVLGSCAELAEEFLESVLSLAHDSNMEVRKQVVAFVEQVCKVKVELLPHVINVVSMLLRDNSAQVIKRVIQACGSIYKNGLQYLCSLMEPGDSAEQAWNILSLIKAQILDMIDNENDGIRTNAIKFLEGVVVLQSFADEDSLKRDGDFSLADVPDHCTLFRREKLQEEGNNILDILLQFHGTTHISSVNLIACTSSLCTIAKMRPIFMGAVVEAFKQLNANLPPTLTDSQVSSVRKSLKMQLQTLLKNRGAFEFASTIRGMLVDLGSSTNEIQKLIPKMDKQEMARRQKRILENAAQSLAKRARLACEQQDQQQREMELDTEELERQKQKSTRVNEKFLAEHFRNPETVVTLVLEFLPSLPTEVPQKFLQEYTPIREMSIQQQVTNISRFFGEQLSEKRLGPGAATFSREPPMRVKKVQAIESTLTAMEVDEDAVQKLSEEEFQRKEEATKKLRETMERAKGEQTVIEKMKERAKTLKLQEITKPLPRNLKEKFLTDAVRRILNSERQCIKGGVSSKRRKLVTVIAATFPDNVRYGIMEFILEDIKQRIDLAFSWLFEEYSLLQGFTRHTYVKTENRPDHAYNELLNKLIFGIGERCDHKDKIILIRRVYLEAPILPEVSIGHLVQLSLDDEFSQHGLELIKDLAVLRPPRKNRFVRVLLNFSVHERLDLRDLAQAHLVSLYHVHKILPARIDEFALEWLKFIEQESPPAAVFSQDFGRPTEEPDWREDTTKVCFGLAFTLLPYKPEVYLQQICQVFVSTSAELKRTILRSLDIPIKKMGVESPTLLQLIEDCPKGMETLVIRIIYILTERVPSPHEELVRRVRDLYQNKVKDVRVMIPVLSGLTRSELISVLPKLIKLNPAVVKEVFNRLLGIGAEFAHQTMAMTPTDILVALHTIDTSVCDIKAIVKATSLCLAERDLYTQEVLMAVLQQLVEVTPLPTLMMRTTIQSLTLYPRLANFVMNLLQRLIIKQVWRQKVIWEGFLKTVQRLKPQSMPILLHLPPAQLVDALQQCPDLRPALSEYAESMQDEPMNGSGITQQVLDIISGKSVDVFVTDESGGYISAEHIKKEAPDPSEISVISTVPVLTSLVPLPVPPPIGSDLNQPLPPGED", "length": 1165 }, "evidence": [ { "id": "E1BJF6", "url": "https://omabrowser.org/oma/group/E1BJF6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q92797-1", "protein_name": "Symplekin", "gene_name": "SYMPK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASGSGDSVTRRSVASQFFTQEEGPGIDGMTTSERVVDLLNQAALITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVISELQEACWDMVSAMAGDIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEIPRRQEHDISLDRIPRDHPYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDTRKRPRDDSDSTLKKMKLEPNLGEDDEDKDLEPGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPEAMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKTESVLIKRRLSAQGQAISVVGSLSSMSPLEEEAPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSDVLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQVRIKILASLVTQFNSGLKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGASGSLDKYEDCLIRLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVVRKYCEDESRTYLGMSTLRDLIFKRPSRQFQYLHVLLDLSSHEKDKVRSQALLFIKRMYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQHGEGNSALSPLNPGELLIALHNIDSVKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMTILEASGKQEPEAKEAPAGPLEEDDLEPLTLAPAPAPRPPQDLIGLRLAQEKALKRQLEEEQKLKPGGVGAPSSSSPSPSPSARPGPPPSEEAMDFREEGPECETPGIFISMDDDSGLTEAALLDSSLEGPLPKETAAGGLTLKEERSPQTLAPVGEDAMKTPSPAAEDAREPEAKGNS", "length": 1274 }, "evidence": [ { "id": "E1BJF6", "url": "https://omabrowser.org/oma/group/E1BJF6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nuclear stress granule", "id": "GO:0097165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097165", "evidence": [ { "database": "UniProtKB", "id": "E1BJF6", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BJF6", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E1BJF6", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BJF6", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "E1BJF6", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" } ], "pmid": "" }, { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "E1BJF6", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "E1BJF6", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "E1BJF6", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJF6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1271, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJF6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJF6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" }, { "id": "PF12295", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12295" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Symplekin C-terminal", "eco_id": "ECO_0000259", "start_pos": 886, "end_pos": 1067, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF6" }, { "id": "PF11935", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11935" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Symplekin/Pta1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 123, "end_pos": 347, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 252, "end_pos": 254 }, { "start_pos": 48, "end_pos": 50 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJF8-1", "uniprot_ac": "E1BJF8", "uniprot_id": "E1BJF8_BOVIN", "mass": { "chemical_mass": 136312.0, "monoisotopic_mass": 136312.0 }, "refseq": { "ac": "XP_024850574", "name": "anoctamin-8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850574" }, "gene_names": [ { "name": "ANO8", "type": "recommended", "evidence": [ { "id": "E1BJF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF8" } ] }, { "name": "ANO8", "type": "synonym", "evidence": [ { "id": "XP_024850574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850574" } ] } ], "protein_names": [ { "name": "Anoctamin", "type": "recommended", "evidence": [ { "id": "E1BJF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF8/entry#names_and_taxonomy" } ] }, { "name": "anoctamin-8", "type": "synonym", "evidence": [ { "id": "XP_024850574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850574" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJF8", "url": "https://www.uniprot.org/uniprotkb/E1BJF8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ANO8", "url": "https://www.uniprot.org/uniprotkb/E1BJF8", "locus": { "chromosome": "7", "start_pos": 5805922, "end_pos": 5794321, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017074", "url": "https://www.ensembl.org/id/ENSBTAG00000017074" } ] } } ], "crossref": [ { "id": "E1BJF8", "url": "https://alphafold.ebi.ac.uk/entry/E1BJF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017074", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017074", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "528201", "url": "https://www.ncbi.nlm.nih.gov/gene/528201", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:528201", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528201", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR12308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12308:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12308:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04547", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04547", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024850574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850574", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NLL1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLL1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJF8", "url": "https://www.uniprot.org/uniprotkb/E1BJF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJF8-1", "url": "https://www.uniprot.org/uniprotkb/E1BJF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEATSGAGGTSLEGERGKRPPPEGEPAAPASGVLDKLFGKRLLQVGRYLVSHKAWMKTVPTENCDVLMTFPDTTDDHTLLWLLNHIRVGIPELIVQVRHHRHTRAYAFFVTATYESLLRGADELGLRKAVKAEFGGGTRGFSCEEDFIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILNRLMKSWVQAVCENQPLDEICDYFGVKIAMYFAWLGFYTSAMVYPAVFGSVLYTFTEADQTSRDVSCVVFALFNVVWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRRISPVTQAEEFYYPPWKRLLFQMLVSLPLCLTCLACVFLLMLGCFQLQELVLSVKGLPRLARFLPKVMLALLVSASAEGYKKLAVWLNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFYLKDMERLKEMLATLLITRQFLQNVREVLQPHLYRRLGRGELGLRAAWELARALLGLLSLWRPARRHLEPPAEEGGGGSSSGGGRRCLSGGCGAPEEEEEAAVERRPAGEGGEVGDGPRGGREEEDEEEEEEDEEEEDEDEEGEEGGLLDCGLRLKKVSFAERGAGRRRPGPSQEALLEEGSPTMVEKGLEPGVFTLAEEDDEAEGAPSSPERETPPAVLLRRAGGEGRDQGPDGGPDPEPGSGDSARKQRRQNRSSWIDPPEEEHSSQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALINNLIEIRSDALKLCTGLQRPFGQRVESIGQWQKVMEVMGVLAIVVNCYLIGQCGQLQRLFPWLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQHRYQQQQRRRREEEERQRHAEHHARRERDASGREEARAEGSGLDPAAPEKTSAKAKGSGAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGASSSSPAGTGANLTTRPTPAQSPTGSDTRLPAFLSFKFLKSPETRRDPERSHSPPKAFHAGKLFPFGGARAEAGSNGAGGQARQDGTLGGGGCRAQRSGLADEAAAEEPDTPRPEEESSGTALAPVGAPALRTRRSRSPAPPPPPPTPMPRPPTPPAGCWQWDGPWGCGGEGAAPRQAPAATDCPPCALAGPPPVPQPLPGDASFYSLPPPPLPPPTSVPPQPPAPSPSPSSSPSPQAVCWPSGWH", "length": 1236, "header": "tr|E1BJF8-1|E1BJF8_BOVIN Isoform 1 of Anoctamin OS=Bos taurus OX=9913 GN=ANO8 PE=3 SV=4 CANONICAL=E1BJF8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NLL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BJF8/entry#A0ABI0NLL1-1", "sequence": { "sequence": "MAEATSGAGGTSLEGERGKRPPPEGEPAAPASGVLDKLFGKRLLQVGRYLVSHKAWMKTVPTENCDVLMTFPDTTDDHTLLWLLNHIRVGIPELIVQVRHHRHTRAYAFFVTATYESLLRGADELGLRKAVKAEFGGGTRGFSCEEDFIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILNRLMKSWVQAVCENQPLDEICDYFGVKIAMYFAWLGFYTSAMVYPAVFGSVLYTFTEADQTSRDVSCVVFALFNVVWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRRISPVTQAEEFYYPPWKRLLFQMLVSLPLCLTCLACVFLLMLGCFQLQELVLSVKGLPRLARFLPKVMLALLVSASAEGYKKLAVWLNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFYLKDMERLKEMLATLLITRQFLQNVREVLQPHLYRRLGRGELGLRAAWELARALLGLLSLWRPARRHLEPPAEEGGGGSSSGGGRRCLSGGCGAPEEEEEAAVERRPAGEGGEVGDGPRGGREEEDEEEEEEDEEEEDEDEEGEEGGLLDCGLRLKKVSFAERGAGRRRPGPSQEALLEEGSPTMVEKGLEPGVFTLAEEDDEAEGAPSSPERETPPAVLLRRAGGEGRDQGPDGGPDPEPGSGDSARKQRRQNRSSWIDPPEEEHSSQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALINNLIEIRSDALKLCTGLQRPFGQRVESIGQWQKVMEVMGVLAIVVNCYLIGQCGQLQRLFPWLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQHRYQQQQRRRREEEERQRHAEHHARRERDASGREEARAEGSGLDPAAPEKTSAKAKGSGAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGASSSSPAGTGANLTTRPTPAQSPTGSDTRLPAFLSFKFLKSPETRRDPERSHSPPKAFHAGKLFPFGGARAEAGSNGAGGQARQDGTLGGGGCRAQRSGLADEAAAEEPDTPRPEEESSGHKL", "length": 1113, "header": "tr|A0ABI0NLL1-1|A0ABI0NLL1_BOVIN Computationally mapped isoform of Anoctamin OS=Bos taurus OX=9913 GN=ANO8 PE=3 SV=1 CANONICAL=E1BJF8-1" }, "locus": { "chromosome": "7", "start_pos": 5803716, "end_pos": 5794556, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141369.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141369.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106012.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106012.1" } ] } }, { "isoform_ac": "E1BJF8-1", "url": "https://www.uniprot.org/uniprotkb/E1BJF8/entry#E1BJF8-1", "sequence": { "sequence": "MAEATSGAGGTSLEGERGKRPPPEGEPAAPASGVLDKLFGKRLLQVGRYLVSHKAWMKTVPTENCDVLMTFPDTTDDHTLLWLLNHIRVGIPELIVQVRHHRHTRAYAFFVTATYESLLRGADELGLRKAVKAEFGGGTRGFSCEEDFIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILNRLMKSWVQAVCENQPLDEICDYFGVKIAMYFAWLGFYTSAMVYPAVFGSVLYTFTEADQTSRDVSCVVFALFNVVWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRRISPVTQAEEFYYPPWKRLLFQMLVSLPLCLTCLACVFLLMLGCFQLQELVLSVKGLPRLARFLPKVMLALLVSASAEGYKKLAVWLNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFYLKDMERLKEMLATLLITRQFLQNVREVLQPHLYRRLGRGELGLRAAWELARALLGLLSLWRPARRHLEPPAEEGGGGSSSGGGRRCLSGGCGAPEEEEEAAVERRPAGEGGEVGDGPRGGREEEDEEEEEEDEEEEDEDEEGEEGGLLDCGLRLKKVSFAERGAGRRRPGPSQEALLEEGSPTMVEKGLEPGVFTLAEEDDEAEGAPSSPERETPPAVLLRRAGGEGRDQGPDGGPDPEPGSGDSARKQRRQNRSSWIDPPEEEHSSQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALINNLIEIRSDALKLCTGLQRPFGQRVESIGQWQKVMEVMGVLAIVVNCYLIGQCGQLQRLFPWLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQHRYQQQQRRRREEEERQRHAEHHARRERDASGREEARAEGSGLDPAAPEKTSAKAKGSGAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGASSSSPAGTGANLTTRPTPAQSPTGSDTRLPAFLSFKFLKSPETRRDPERSHSPPKAFHAGKLFPFGGARAEAGSNGAGGQARQDGTLGGGGCRAQRSGLADEAAAEEPDTPRPEEESSGTALAPVGAPALRTRRSRSPAPPPPPPTPMPRPPTPPAGCWQWDGPWGCGGEGAAPRQAPAATDCPPCALAGPPPVPQPLPGDASFYSLPPPPLPPPTSVPPQPPAPSPSPSSSPSPQAVCWPSGWH", "length": 1236, "header": "tr|E1BJF8-1|E1BJF8_BOVIN Isoform 1 of Anoctamin OS=Bos taurus OX=9913 GN=ANO8 PE=3 SV=4 CANONICAL=E1BJF8-1" }, "locus": { "chromosome": "7", "start_pos": 5804918, "end_pos": 5794556, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022706.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022706.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022706.7", "url": "https://www.ensembl.org/id/ENSBTAP00000022706.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1008, "start_aa": "Thr", "end_pos": 1008, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1008", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1137, "start_aa": "Thr", "end_pos": 1137, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1137", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1144, "start_aa": "Thr", "end_pos": 1144, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1144", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:528201", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528201", "resource": "KEGG Pathway" }, { "id": "R-BTA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" }, { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-BTA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BJF8", "url": "https://www.uniprot.org/uniprotkb/E1BJF8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BJF8", "url": "https://www.uniprot.org/uniprotkb/E1BJF8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "intracellularly calcium-gated chloride channel activity", "id": "GO:0005229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005229", "evidence": [ { "database": "UniProtKB", "id": "E1BJF8", "url": "https://www.uniprot.org/uniprotkb/E1BJF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1002, "end_pos": 1004, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJF8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1236, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJF8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJF8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJF8" }, { "id": "PF04547", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04547" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anoctamin transmembrane", "eco_id": "ECO_0000259", "start_pos": 237, "end_pos": 582, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1008, 1137, 1144 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1002, "end_pos": 1004 }, { "start_pos": 712, "end_pos": 714 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", 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}, "isoforms": [ { "isoform_ac": "E1BJG2-1", "url": "https://www.uniprot.org/uniprotkb/E1BJG2/entry#E1BJG2-1", "sequence": { "sequence": "MGDPPPDPEPPSQPTSSSRNSQVSERRRSRERTRPLVPEELQQIPLDPQRNLRGWPQRASLTPNENLVFQAEDPYVNPGFSAEVQPQAYLSEGRLQASHNASLMLPQLQQGEGNLFQQLESAYQGPPADLPGQFTMYQREDLPFSQGTQHGPYMRDDPTLQFSPSELGFMSFNMELPEPEPRELAVQNAKAYLLQTSVNSDLSLYEHLANMLTKILNQRPEDPLFLLESLNRTTQWEWFHPKLDTLRDDPEMQPTYEMAERQKALFGRSGSGEGEQEMEEETAETAVPNIMEKAFYFEQAGVGLSSDESFRVFMALKQLVEQQPIHTCRFWGKILGLSRSYLVAEVEFREGEEEAEEEEVEEMTEGGEGMEAHGEEEGDEDEDKATDVIPKPTWKPPPVIPKEDSRTGTNRYLYFVCNEPGRPWMRLPHVTPIQIVQARKIRKFFTGYLDAPVISYPPFPGNEANYLRAQIARISAATHISPLGFYQFGEEEGDEEEEGGAGRDSYEENPDFEGIPVLELVDSMANWVHHTQHILPQGRCTWVNPLQKTEEEEELGEEEEKADEGVEEVEQEVGPPLLTPLSEDAEIMHMAPWTARLSCTLSPQYSVAVVRSNLWPGAYAYASGKKFENIYIGWGHKYSPENFNPSLPAPIQHEYPSGPDTIEMSDPTVEEEQALKAAQEQALAAAEEEEEDEEEDEDEDQDD", "length": 703, "header": "tr|E1BJG2-1|E1BJG2_BOVIN Isoform 1 of Radial spoke head 6 homolog A OS=Bos taurus OX=9913 GN=RSPH6A PE=1 SV=4 CANONICAL=E1BJG2-1" }, "locus": { "chromosome": "18", "start_pos": 53350461, "end_pos": 53330306, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016038.7", "url": "https://www.ensembl.org/id/ENSBTAT00000016038.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016038.7", "url": "https://www.ensembl.org/id/ENSBTAP00000016038.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structural diversity of axonemes across mammalian motile cilia.", "journal": "Nature", "date": "2025", "authors": "Leung Miguel Ricardo, Sun Chen, Zeng Jianwei, Anderson Jacob R, Niu Qingwei, Huang Wei, Noteborn Willem E M, Brown Alan, Zeev-Ben-Mordehai Tzviya, Zhang Rui", "evidence": [ { "database": "UniProtKB", "id": "E1BJG2", "url": "https://www.uniprot.org/uniprotkb/E1BJG2" } ], "reference": [ { "type": "PubMed", "id": "39743588", "url": "https://glygen.org/publication/PubMed/39743588" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "E1BJG2", "url": "https://www.uniprot.org/uniprotkb/E1BJG2" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "E1BJG2", "url": "https://www.uniprot.org/uniprotkb/E1BJG2" } ], "pmid": "" }, { "name": "radial spoke head", "id": "GO:0001535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001535", "evidence": [ { "database": "UniProtKB", "id": "E1BJG2", "url": "https://www.uniprot.org/uniprotkb/E1BJG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "E1BJG2", "url": "https://www.uniprot.org/uniprotkb/E1BJG2" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "E1BJG2", "url": "https://www.uniprot.org/uniprotkb/E1BJG2" } ], "pmid": "" }, { "name": "manchette disassembly", "id": "GO:1905199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905199", "evidence": [ { "database": "UniProtKB", "id": "E1BJG2", "url": "https://www.uniprot.org/uniprotkb/E1BJG2" } ], "pmid": "" }, { "name": "sperm flagellum assembly", "id": "GO:0120316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120316", "evidence": [ { "database": "UniProtKB", "id": "E1BJG2", "url": "https://www.uniprot.org/uniprotkb/E1BJG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": 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"MGQEPRTLPPSPNWYCSRCSDAVPGGLFGFAARTSVFLVRVGPGADAIPGTPPFRVIGELVGHTEKVSGFTFCHHPGQYNLCATSSDDGTVKIWDVGTKTVVTEHALHQHTISALHWSPRVKDLIVSGDEKGVVFCYWLNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVMHRLRGHDDEIHSIAWCPLSGEDCLSINQEENSEEPEMPNGKVITQTPVTKGCYLATGSKDQTIRIWSCSRGRGVMTLKLPFLKRRGGGVDPTVKERLWLTLHWPKDQPTQLVSSCFGGELLLWDLTQSWRRKYTLFSGSSEGQNHSRIVFNLCPLQTEDDKQLLLSISMDRDVKCWDMATLECCWSLPSLGGFAYSLAFSPVDTGCLAIGVGDGMIRVWNTLSIKNNYDVKHFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYSLAWGPPVPAMALGEGDRPSLTLYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFKLPNLKLICSIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLQTVIESNPQSPVTITEPYRTLSGHTAKITSLAWSPHHDGRLVSASYDGTAQVWDTLQEEPLCNFRGHRGRLLCVVWSPLDPDCIYSGADDFCVYKWLTSMQEHSRPPQGKKSIELEKKRLSQPKPKPKKKKKPTLRVPVRQELCDGNEEESVKESLGPIENGVSDQETEEEAREPEPPCGVTAAVSKEPIICTPAALGFEKSKSTINNKVTLLKKEVPKEKPEALIKKRKARSMLPLSTSLDHRSKEELHQDCLVLATAKHSTAGPNEDVSTDLEERFHLGLFTDRATLYRMIEVEGKSHLENGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPVAGYHVWVWAVEAFAKQLCFQDQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKARLRPEDPIIKDLYLSWGAILEKDGHYALAAKCYLGATSAYDAAKVLAKKGDAASLRTAAELASIVGENELSASLALRCAQELLLARNWVGAQEALQLHTSLKGQRLVFCLLELLSKHLEEKQLSEGKSSFSSYNDWPTDSEGSFVERVTAVWKSTFGLDSPEQYQAAFQQLQNIKYPSATSNTPSKQLLLHICHDLTLAVLSQEAGSWDAAVEGLLRAVIRSYDSANFTIMQEVHSAFLPQGCDHLRDKLGDHQSPTTPAFKSLKAFFIYGCLYEFWWSLSGPCPESSVWLRAAHRSKTSTEQSQEVDSVSPEETDPKPSQPEPSRTPELDVRLSEEGEQMQNACKELLSEKHAGLQNAQRTVAEVQETLAEMIRQHQKSQLCKSTANGPDKNEPEQEGQSLSHPQNQCKEEKNEPVSLPELTKRLTEANERIAKLPESIKTWPFPDVLECCLILLHIGSQCPSFVTQEMQQQAQEFLQKYGNTKVYKRHYQTLCT", "length": 1509, "header": "tr|E1BJG3-1|E1BJG3_BOVIN Isoform 1 of Gem-associated protein 5 OS=Bos taurus OX=9913 GN=GEMIN5 PE=3 SV=3 CANONICAL=E1BJG3-1" }, "isoforms": [ { "isoform_ac": "E1BJG3-1", "url": "https://www.uniprot.org/uniprotkb/E1BJG3/entry#E1BJG3-1", "sequence": { "sequence": "MGQEPRTLPPSPNWYCSRCSDAVPGGLFGFAARTSVFLVRVGPGADAIPGTPPFRVIGELVGHTEKVSGFTFCHHPGQYNLCATSSDDGTVKIWDVGTKTVVTEHALHQHTISALHWSPRVKDLIVSGDEKGVVFCYWLNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVMHRLRGHDDEIHSIAWCPLSGEDCLSINQEENSEEPEMPNGKVITQTPVTKGCYLATGSKDQTIRIWSCSRGRGVMTLKLPFLKRRGGGVDPTVKERLWLTLHWPKDQPTQLVSSCFGGELLLWDLTQSWRRKYTLFSGSSEGQNHSRIVFNLCPLQTEDDKQLLLSISMDRDVKCWDMATLECCWSLPSLGGFAYSLAFSPVDTGCLAIGVGDGMIRVWNTLSIKNNYDVKHFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYSLAWGPPVPAMALGEGDRPSLTLYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFKLPNLKLICSIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLQTVIESNPQSPVTITEPYRTLSGHTAKITSLAWSPHHDGRLVSASYDGTAQVWDTLQEEPLCNFRGHRGRLLCVVWSPLDPDCIYSGADDFCVYKWLTSMQEHSRPPQGKKSIELEKKRLSQPKPKPKKKKKPTLRVPVRQELCDGNEEESVKESLGPIENGVSDQETEEEAREPEPPCGVTAAVSKEPIICTPAALGFEKSKSTINNKVTLLKKEVPKEKPEALIKKRKARSMLPLSTSLDHRSKEELHQDCLVLATAKHSTAGPNEDVSTDLEERFHLGLFTDRATLYRMIEVEGKSHLENGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPVAGYHVWVWAVEAFAKQLCFQDQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKARLRPEDPIIKDLYLSWGAILEKDGHYALAAKCYLGATSAYDAAKVLAKKGDAASLRTAAELASIVGENELSASLALRCAQELLLARNWVGAQEALQLHTSLKGQRLVFCLLELLSKHLEEKQLSEGKSSFSSYNDWPTDSEGSFVERVTAVWKSTFGLDSPEQYQAAFQQLQNIKYPSATSNTPSKQLLLHICHDLTLAVLSQEAGSWDAAVEGLLRAVIRSYDSANFTIMQEVHSAFLPQGCDHLRDKLGDHQSPTTPAFKSLKAFFIYGCLYEFWWSLSGPCPESSVWLRAAHRSKTSTEQSQEVDSVSPEETDPKPSQPEPSRTPELDVRLSEEGEQMQNACKELLSEKHAGLQNAQRTVAEVQETLAEMIRQHQKSQLCKSTANGPDKNEPEQEGQSLSHPQNQCKEEKNEPVSLPELTKRLTEANERIAKLPESIKTWPFPDVLECCLILLHIGSQCPSFVTQEMQQQAQEFLQKYGNTKVYKRHYQTLCT", "length": 1509, "header": "tr|E1BJG3-1|E1BJG3_BOVIN Isoform 1 of Gem-associated protein 5 OS=Bos taurus OX=9913 GN=GEMIN5 PE=3 SV=3 CANONICAL=E1BJG3-1" }, "locus": { "chromosome": "7", "start_pos": 66104481, "end_pos": 66065439, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016037.7", "url": "https://www.ensembl.org/id/ENSBTAT00000016037.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016037.6", "url": "https://www.ensembl.org/id/ENSBTAP00000016037.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:533444", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533444", "resource": "KEGG Pathway" }, { "id": "R-BTA-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-191859", "resource": "Reactome", "description": "snRNP Assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YL91-1", "protein_name": "Gem nuclear organelle associated protein 5", "gene_name": "GEMIN5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAVRVLPASPNWYCSRCSDTSGDGRLFGFAARHRISVLDVSTATPTFHGELIGHTERIAAFAFCPHREHGALCASGSDDGSVRLWDAAGLVLRGEHGLHQNAITALHWSPLVKDLIVSGDEKGVIVCYWHSRSDSQQFFPEPRTIFCLTCSPHHENLVAVGYKDGMVVIIDISRKKEVLHRLRGHDDEIHCLAWCPVPGEGRLPAWQDELQEESDVPNGELKQDTAMKKSCYLASGSKDQTIRIWSCTRGRSVMTLKLPPTKRRGGAVDPAVKERIWLTVHWPCGRPTEIVSSSFGGELLHWDLTQPGKRKWTLLGSSEGQNHSRIVFNLCPLKHQDKELLLSISMDRDVKCWDLSTLDCSWTMPSLGGFVYSLAFSPVDPGCLAIGVGDSMIRVWNTLSMSNMFDVKTYWQSIKSKVTALAWHPTKEGCLAFGTDDGKVGIFDTLSSSAKNKPPQISSTYHKRTVYTLAWGPPTPPLSSGEEGEHPSVTLYSCAGEGIVFQHNPWKLSGEANDINKTIRDTNSIKHKLPARTEISWKPDGKLLALGNEDGSIEIFQAPNLKLLCTIQQHHKLINAIRWHHEHGSDPELSYLIASGSVNAIIYVHNLKSVIESTSESPLTITEPFRTLAGHTSKVTSLSWSPHHEGRLVSACYDGTAQVWDVMKEEPLCNYRGHQGRLLCVQWSPVDSDSIYTGADDFSVHKWLISKQEHTRPPQGKKSIELEKKRSIQPKVKAKKKKKPVGRSPAKQDQSDAVNGDESMKDTLLEENGVSDHEGEKEAQETELPDKDSIAVSKDTSLSAYDYSSLSSSKPFVTQKATPVKKDPPKEKPAPDASLKKRKPRSLLPFSTSMDHRSKDELHQDCLRLATCLKTKDHNEDVSPDLQNRIHLGLFTDRASLHNMIDVEGKYHLENGHPELFQQLMLWKGDMKGVLQAAAERGELTDQLVAMSPMVGYQAWVWTVEAFAKQLCFQEQYVKAASHLLSIHKVYEAVELLKVNNFYREAIVIAKARLRPEDPILKDLYTSWAALLEKDGHYSMAAKCYLGASSPYDAVKVMAKKGDAASLKTAAELALISGEEELSASLSFRCAQEMLLSRNWVGAQEVLQQQKTLFGQRLVFCLNELLCKCLSERNPCNRRSPVPPCYHSWELKRDASFFDMVIEVWQKVLGMDTTEKATCAWEQLHSIEHPPSTSNTHPKQVLFYISHDLTLAALSYQAAAWDEVVKSILGAVARSYDAGNFTLMQEICSIFLPEGCENLRDKLDSTNSQSMDACRSLEGFVACGLLYDLWWNPPKDPPAIQKACLDPALCPTEQTVLEQSCIPDHSSPEETPDQTAVETDENLNSTTEFNRCKTESDSKTNSVSLADRQSKLNGCKVLLSEAIAALQSTQRDIAEVQKILADMIHQHQQQRNNLQESTNGSIHENNVQQSSENELDEPLSDSSQIKRKDEVKETVTLPELTKRLMEAKQKLAEFPDSLKVFPFPDVLECCLVLLHIGAQCPPELHEQALDLLRKHEPTTDDEHMDFCISKDKHTSALEGGITP", "length": 1541 }, "evidence": [ { "id": "E1BJG3", "url": "https://omabrowser.org/oma/group/E1BJG3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZGD0-1", "protein_name": "Gem-associated protein 5", "gene_name": "Gemin5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPEPRTLPPSPNWYCARCSDAAPGGIFGFAARTSVFLVRVGPGAGASPGAPPFRVVGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKAVVTEHALHQHTISALHWSPTVKDLIVSGDEKGVVFCYWLNRSDSQHLFTEPRAIFCLTCSPHHENLVAIGYKDGIVIIIDISKKGEVVHRLRGHDDEIHSIAWCPLSGEDCLSINQEENSEEPDIPNGKLIAETPITKGCYLATGSKDQTIRIWSCSRGRGVMVLKLPFLKRRSGGVDPTVKERLWLTLHWPKNQPTQLVSSCFGGELLLWDLTQSWRRKYTLFSTSAEGHNHSRIVFNLCPLKTEDGKQLLLSTSMDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDGKVGLYDTCSNKPPQISSTYHKKTVYRLAWGPPVPPMSLGGEGDRPSLTLYSCGGEGIVLQHNPWKLSGEAFDINKLMRDTNSIRYKLPVHTEISWKGDGKVMALGNEDGSIEIFQVPNLKLLCTIQQHHKLVNAIVWHHEHGSRPELSCLLASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKVTSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGADDFCVYRWLTSMQDHSRPPQGKKCIELEKKRLSQFKPKLKKKKKPTLRLPIKQDSSIGNEDESVRENLAPVENGLSDQDGEEEAQEPELPPSPVVCGEPVSCTAVSLGLEKSKVTVTSKVASLKKEPPKEKPEALLKKRKARSMLPLSTSLDHRSKEELHRDCLVLATATHARAELHEDVSADLEERFHLGLFTDRAALYRMMETEGKGHLESGHPELFHQLMLWKGDLKGVLQAAAERGELTDSLVAVAPVAGYSVWLWAVEAFAKQLCFQDQYVKAASYLLSIHRVYEAVELLRSNHLYREAIAVAKARLRPEDPVLKDLYLSWGSILERDGHYAIAAKCYLGATSAYDAAKVLARKGDAASLRTAAELAAIAGESELAASLALRCAQELLLLKNWVGAQEALGLHESLQGQRLVFCLLELLCRHLEEKQPPEVRGPSSIYHQWATGSEGTLVQRVTGVWRSAFSVDTPEQCRAALQKLQDVKYPSATSNTPFRQLLLHVCHDLTLAMLSQQAASWEEAVPALLQAVVRSYTSGNFTLMQEIYSAFLPGGCDHLRDKLGDLSPTMAAFKSLEAFFIYGQLYEVWWSLCGPGSESSIWVWSAESTVSDKQSKPGDSASAEDMEQPLGPGLRLSAESERLLSACKELFSERHASLQTSQRTVAEVQETLAEMIRQHQKSQLCKATANGPNRDEPSQQAERAPSQPPSPTREERNAPVSLPELTRRLTEANERIAEFPESVKAWPFPDVLECCLVLLHIGSQCPGAVNPEMQQQAQKLLQKYGHTRAYRRHCQIRHT", "length": 1498 }, "evidence": [ { "id": "E1BJG3", "url": "https://omabrowser.org/oma/group/E1BJG3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54IY5-1", "protein_name": "Component of gems protein 5", "gene_name": "gemin5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNIDSNIIKNENLINANNHTDRRDVHDSLAEAPEKITELKKNHWEELLPSSSNWYCTSVADCNENQIYIYACKSNVSIFNIKSKKFIGELNGHTDRVTSVGFFKRFESKNDESYKWCITGSDDKTVRIWKFNSNDDDHNEDTEIGDDFKHGSGGGGSDGGGGDDVNNFYGNKSSNFCIYYHQEHKAGVTCVVASPLVPDLVLSGDKAGALVIYRTLTNHVFPIPPIIGNNISISTLAFSPNHSDLVAIGYLNGIVLIYNFVIRSTVCKISAHSADVLSIVWFDSTIIQKNNIFHDNNINDQDDNNSNHRNRIFLATCSKDKAIKIWKQVGEKIESGFTNIYQFNPSKYSIQHSSSSGGGGINQNDKQRVWLTLSWSPESPQYLLSNSLTADVLIWDLINFKSPPEKFQSSHQRLIFNITQIPNSDGSLAKTTATTETTTKNKIKNKDKKQSQIKLNNKVITVSLDRQIIIWENLKAKIKIQGLGGFVYSIDTCSYSPNTFAIGCGDNTIRLWSPTENSKDAYESKTLWKGIQSKVTSLSICKDYGFSNSNLIAFGMDDGRVGVYNINTNQSKIFPGGHKNEIYEIIWKPPPTPTPQKNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNNNNNNSNNEQQPNKLYSIGNNEIYEWDYNDFNKSFTNMTPIIQQLNPKETFSKHKTDINFNLNGDMISIGYSDGTIDIFTSEFLFLTRIREHKKLINRVQWNHFKENEMILASASTDKKVIIYKLSKIGNQNENEKKIDNEKGKENENEKGKENENENENENENENENENENEIENIVNNNNENDTEIEIKNINKNENVDKEEMVENNNNNNIKYKIEILHQFIGHKNNVCSVSWSNVDPNLLGSASADGTVQVWNIKSKEAISNMRGHDGRVFTVCWSLLDPNLLVSGGEDQTVRLWNYSTQPFKTVTESQIKKSPQPELSISLNKKITEQQQQQQQPQSPIKSNPDQSNNPSLVPPILLTSVTSTSNTTATATTITQITESLPKKRPIFLLNKDIVQRQDSSQYVVPLAKYFTTNDQDSINTNETKQEYEFGSNSENNNSKIEAIFSEKKEIINKLVQKESLELLKIDDVENYISLNSWNPANLKQALYQVIKNGKLTGNIVSLSIQAGREIFESICNLYSQQLICIGDYHLAVSYLLMIGKVNEAIEVYRNTLLFQEAIILAKSRFLPDDPIINKLFTEWAKQTETSHPIHSIKCYLATINDQSLNSKQELLKLLSSVQTKQIIKIQSDLEQILK", "length": 1276 }, "evidence": [ { "id": "E1BJG3", "url": "https://omabrowser.org/oma/group/E1BJG3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BX17-1", "protein_name": "Gem-associated protein 5", "gene_name": "Gemin5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPEPRTLPPSPNWYCSRCSDAAPGGIFGFAARTSVFLVRVGPGAGASPGAPPFRVVGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSPTVKDLIVSGDEKGVVFCYWLNRNDSQHLFTEPRTIFCLTCSPHHENLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLSGEDCLSISQEENSEEPDIPNGKLIAETPITKGCYLATGSKDQTIRIWSCSRGRGVMVLKLPFLKRRSGGVDPTVKERLWLTLHWPKNQPTQLVSSCFGGELLLWDLTQSWRRKYTLFSTSAEGHNHSRIVFNLCSLKTEDGKQLLLSTSMDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDGKVGLYDTCSNKPPQISSTYHKKTVYRLAWGPPVPPMSLGGEGDRPSLTLYSCGGEGVVLQHNPWKLSGEAFDINKLVRDTNSIRYKLPVHTEISWKGDGKVLALGNEDGSIEIFQVPNLRLLCTIQQHHKLVNAIVWHHEHGSRPELSCLLASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGADDFCVYRWLTSMQDHSRPPQGKKCIELEKKRLSQFKPKLKKKKKPTLRLPVKQDSSVGNEDESVKENSGPAENGLSDQDGEEEAQEPELPPSPVVCVEPVSCTDICSGFEKSKVTVSSKATSLKKEPAKEKPEALLKKRKARSMLPLSTSLDHRSKEELHRDCLVLATATHAKAELNEDVSADLEERFHLGLFTDRATLYRMMETEGKGHLESGHPELFHQLMLWKGDLKGVLQAAAERGELTDSLVAVAPVAGYSVWLWAVEAFAKQLCFQDQYVKAASYLLSIHKVYEAVELLKSNHLYREAIAVAKARLRPEDPVLKELYLSWGSILERDGHYAIAAKCYLGATSAYDAAKVLARKGDAASLRTAAELAAIAGEHELAASLALRCAQELLLMKNWVGAQEALGLHESLQGQRLVFCLLELLCRHLEEKQPLEVRGPSSIYHQWATGSEGTLVQRVTGVWRSAFSVDTPEQCQAALQKLQDVKYPSATSNTPFRQLLLHVCHDLTLAMLSQQAAAWEEAVPALLQAVVRSYTSGNFTLMQEIYSAFLPGGCDHLRDKLGDLSPAMAAYKSLEAFCIYGQLYEVWWSLCGPGPESSVWVLSAESTVSDKQSKPEDSASAEDMEQPPGPGPRLSAESERLLSACKELFSERHASLQTSQRTVAEVQETLAEMIRQHQKSQLCKATTNGPSRDEPSRDEPSQEAERAPSQPPSPTEERNAPVSLPELTRRLTEANERIAEFPESVKAWPFPDVLECCLVLLHIGSQCPDAVDPEMQQQAQELLHKYGHTRAYRRHCQSRHT", "length": 1502 }, "evidence": [ { "id": "E1BJG3", "url": "https://omabrowser.org/oma/group/E1BJG3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TEQ6-1", "protein_name": "Gem-associated protein 5", "gene_name": "GEMIN5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQGKKSIELEKKRLSQPKAKPKKKKKPTLRTPVKLESIDGNEEESMKENSGPVENGVSDQEGEEQAREPELPCGLAPAVSREPVICTPVSSGFEKSKVTINNKVILLKKEPPKEKPETLIKKRKARSLLPLSTSLDHRSKEELHQDCLVLATAKHSRELNEDVSADVEERFHLGLFTDRATLYRMIDIEGKGHLENGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPAAGYHVWLWAVEAFAKQLCFQDQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKARLRPEDPVLKDLYLSWGTVLERDGHYAVAAKCYLGATCAYDAAKVLAKKGDAASLRTAAELAAIVGEDELSASLALRCAQELLLANNWVGAQEALQLHESLQGQRLVFCLLELLSRHLEEKQLSEGKSSSSYHTWNTGTEGPFVERVTAVWKSIFSLDTPEQYQEAFQKLQNIKYPSATNNTPAKQLLLHICHDLTLAVLSQQMASWDEAVQALLRAVVRSYDSGSFTIMQEVYSAFLPDGCDHLRDKLGDHQSPATPAFKSLEAFFLYGRLYEFWWSLSRPCPNSSVWVRAGHRTLSVEPSQQLDTASTEETDPETSQPEPNRPSELDLRLTEEGERMLSTFKELFSEKHASLQNSQRTVAEVQETLAEMIRQHQKSQLCKSTANGPDKNEPEVEAEQPLCSSQSQCKEEKNEPLSLPELTKRLTEANQRMAKFPESIKAWPFPDVLECCLVLLLIRSHFPGCLAQEMQQQAQELLQKYGNTKTYRRHCQTFCM", "length": 1508 }, "evidence": [ { "id": "E1BJG3", "url": "https://omabrowser.org/oma/group/E1BJG3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "U4 snRNA binding", "id": "GO:0030621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030621", "evidence": [ { "database": "UniProtKB", "id": "E1BJG3", "url": "https://www.uniprot.org/uniprotkb/E1BJG3" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "E1BJG3", "url": "https://www.uniprot.org/uniprotkb/E1BJG3" } ], "pmid": "" }, { "name": "RNA 7-methylguanosine cap binding", "id": "GO:0000340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000340", "evidence": [ { "database": "UniProtKB", "id": "E1BJG3", "url": "https://www.uniprot.org/uniprotkb/E1BJG3" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "E1BJG3", "url": "https://www.uniprot.org/uniprotkb/E1BJG3" } ], "pmid": "" }, { "name": "U4atac snRNA binding", "id": "GO:0030622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030622", "evidence": [ { "database": "UniProtKB", "id": "E1BJG3", "url": "https://www.uniprot.org/uniprotkb/E1BJG3" } ], "pmid": "" }, { "name": "U1 snRNA binding", "id": "GO:0030619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "evidence": [ { "database": "UniProtKB", "id": "E1BJG3", "url": "https://www.uniprot.org/uniprotkb/E1BJG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BJG3", "url": "https://www.uniprot.org/uniprotkb/E1BJG3" } ], "pmid": "" }, { "name": "cytosol", "id": 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SV=1 CANONICAL=E1BJK7-1" }, "isoforms": [ { "isoform_ac": "E1BJK7-1", "url": "https://www.uniprot.org/uniprotkb/E1BJK7/entry#E1BJK7-1", "sequence": { "sequence": "MAAWAVISLSRAAAQCLWARGPGVRGAVPPSALAFQPEPPCCSAAGGRTLHLTAEVPAGHNKWSKVRHIKGPKDAERSRIFSKLSLSIRLAVKEGGPNPELNSNLASILEVCRSKHMPKSTIEAALKMEKTKDMYLLYEGRGPGGSSLLIEALSNSSSKCHSDIKHILNKNGGMMAEGARHSFDKKGVIVVGEEDREKKPVNLERALELAIEAGAEDVAETEDEEEKNIFKFICDASSLHQVRKKLDSLGLCSVSCTLEFIPNTKVRLADPDLEQAAHLIQALGNHDDVIHVYDNIE", "length": 297, "header": "tr|E1BJK7-1|E1BJK7_BOVIN Isoform 1 of Translational activator of cytochrome c oxidase 1 OS=Bos taurus OX=9913 GN=TACO1 PE=3 SV=1 CANONICAL=E1BJK7-1" }, "locus": { "chromosome": "19", "start_pos": 47905908, "end_pos": 47902089, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013031.4", "url": "https://www.ensembl.org/id/ENSBTAT00000013031.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013031.1", "url": "https://www.ensembl.org/id/ENSBTAP00000013031.1" } ] } } 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[ "Protein Classification" ] }, { "id": "E1BJL3", "url": "https://www.orthodb.org/?gene=E1BJL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03131", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03131", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9707616", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9707616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9708530", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9708530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002684658", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002684658", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJL3-1", "url": "https://www.uniprot.org/uniprotkb/E1BJL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLGENAVFAYESSVHGAHVLRCLDEQRRKDELCDVTVLVEGRPFRAHRAVLAACSAYFHARLAGAAGPEPRITLPAEVTVKGFEPLIQFAYTAKLILSKDNVDEVYKCVEFLGVPDIEESCFQFLKYKFLDSTADQQECPRKKCFSSPCQKPDFKFSLLDQKDLEIDEVEEFLDNKNVQTPHCKLRRYQGSAKATPPLQDSASQTCESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTVESSVKDIQAASVQPHEPSENECLGGIQDCADLQVILKCEERKSAMEHEEAKKKDLASQGSSGKTETTPCPPNSADPHRFYSLSVLHTYDQYGDLNFAGTQNTTVLTEKPSSGSDVREEKAFGESPDVKSDSGPRKESGLAASDLSSVEREVAEHLAKGFWSDVCNTDAPCQMQLSPVVAKDGPEQNYPQKRSECPWLGIRISESPEPGQRTFTTLSSVSCPFISTLSPEGCSSSLEIGTDDYASEPQQEPCPYACVISLGDDSETDTEGDSEPCSAREQECEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKESLLKERDHILSTLGETKQNLTGLCQQVCKEAALSQEQIQILAKYSASDCPLSLLISEKGKSTPDSELALPSILSLSERPAAGLPAGEPSLCYPSTKGGEAGGVRGQESQTATSTLSETREPCRQSGGISDFCQQMTDKCTTDE", "length": 741, "header": "tr|E1BJL3-1|E1BJL3_BOVIN Isoform 1 of BTB domain and CNC homolog 1 OS=Bos taurus OX=9913 GN=BACH1 PE=3 SV=1 CANONICAL=E1BJL3-1" }, "isoforms": [ { "isoform_ac": "E1BJL3-1", "url": "https://www.uniprot.org/uniprotkb/E1BJL3/entry#E1BJL3-1", "sequence": { "sequence": "MWLGENAVFAYESSVHGAHVLRCLDEQRRKDELCDVTVLVEGRPFRAHRAVLAACSAYFHARLAGAAGPEPRITLPAEVTVKGFEPLIQFAYTAKLILSKDNVDEVYKCVEFLGVPDIEESCFQFLKYKFLDSTADQQECPRKKCFSSPCQKPDFKFSLLDQKDLEIDEVEEFLDNKNVQTPHCKLRRYQGSAKATPPLQDSASQTCESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTVESSVKDIQAASVQPHEPSENECLGGIQDCADLQVILKCEERKSAMEHEEAKKKDLASQGSSGKTETTPCPPNSADPHRFYSLSVLHTYDQYGDLNFAGTQNTTVLTEKPSSGSDVREEKAFGESPDVKSDSGPRKESGLAASDLSSVEREVAEHLAKGFWSDVCNTDAPCQMQLSPVVAKDGPEQNYPQKRSECPWLGIRISESPEPGQRTFTTLSSVSCPFISTLSPEGCSSSLEIGTDDYASEPQQEPCPYACVISLGDDSETDTEGDSEPCSAREQECEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKESLLKERDHILSTLGETKQNLTGLCQQVCKEAALSQEQIQILAKYSASDCPLSLLISEKGKSTPDSELALPSILSLSERPAAGLPAGEPSLCYPSTKGGEAGGVRGQESQTATSTLSETREPCRQSGGISDFCQQMTDKCTTDE", "length": 741, "header": "tr|E1BJL3-1|E1BJL3_BOVIN Isoform 1 of BTB domain and CNC homolog 1 OS=Bos taurus OX=9913 GN=BACH1 PE=3 SV=1 CANONICAL=E1BJL3-1" }, "locus": { "chromosome": "1", "start_pos": 6831796, "end_pos": 6816144, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005416.4", "url": "https://www.ensembl.org/id/ENSBTAT00000005416.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005416.2", "url": "https://www.ensembl.org/id/ENSBTAP00000005416.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:531350", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531350", "resource": "KEGG Pathway" }, { "id": "R-BTA-9707616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9707616", "resource": "Reactome", "description": "Heme signaling" }, { "id": "R-BTA-9708530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9708530", "resource": "Reactome", "description": "Regulation of BACH1 activity" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A481CED7-1", "protein_name": "BTB domain and CNC homolog 1", "gene_name": "BACH1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLGESAVFAYESSVHSAHVLLSLDEQRRKDVLCDVTVLVEGQPFRAHRAVLAACSAYFHARLSGQADAELRITLPEEVTVKGFEPLIQFAYTAKLILSKDNVDEVCKCVEFLGVSDIEESCFQFLKYKFLDSAADQQECPRKKCFSSSCQKPDFKFSLLDQKDLEIDEVEEFLEHKNVRTPHCKLRRYQGSAQVLPPLQDSASQTCESMCLEKDAALSLPSLCPKYRKFQKAFGTDRVRAVESSVKDIHTSSVQPNEPSERECSGGVQDCADLQVILKCEERKLAMEHEEAKKKDPASQCPSEKTGATPFPPSSTDPHGLYSLSLLHTYDQYGDLNFAGMQNTAVLTEKPLSGSDVQEEKTFGESQDLRLKSDSGSREDSSLASSDLSSVEREVAEHLAKGFWTDICSTDSPCQMQLSPAMAKDGSEQIYSQKRSECPWLGIRISESPEPGQRTFTTLSSVNCPFISTLSTEGSSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSEPCSAREQECEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKESLLKERDHILSTLGETKQNLTGLCQQVCKEAALSQEQIQILAKYSASDCPLSFLVSEKGKSSSDGELVLPSILSLPEGPAAAPPSGEQSPHYPSAKGSEAGQESSATVSAPSEPAGPGEQCRQSGGISDFCQQMTDKCTTDE", "length": 742 }, "evidence": [ { "id": "E1BJL3", "url": "https://omabrowser.org/oma/group/E1BJL3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YE10-1", "protein_name": "BTB domain and CNC homolog 1", "gene_name": "BACH1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSLSEKNSVVFAYESSVHSTNVLLSLDDQRKQDILCDVTILVEDQRFRAHKAVLAACSSYFLSRIVGQLDADLIITLPEEVTLKGFSPLLQFAYTAKLILNKDNVSEVCKCAEFLGVRNIEESCFQFLKFKFLDCKSDQECPRKKCCTQHCRKVNPKISSVDDGDLEIDDEAEELIEKEYIQTSHTKLCKDDENAKASPALQDNTNPTSDPMHLEKGNVSSSSSQCPKYRKFQKAFGNDKVHTSDSSSSTKDIQVPPTVTFIEKEIPDNDSTPKAQECVPMQLVSQCEEAQVKMEEGEEDIEKKEESKRDSVTESISCPVEKMDVAAFPQNAAAPHGLNSVSFLRTCEQYGNLNFSSMQSTTILSEKTATGTGAESDKIESHDNATLKVDLCAREAINITSTGDRSSVEREVAEHLAKGFWSDIYSTEACQIHLPSAVPKERLEPAYSGKKSECPWLGIRISESPEPCSQRTFTTLSSVKCPFISNLSTEGCSNSSEISSGDYVQGQQQEQCPYNYVISLGEDSETDTEGDSESCSAREQECEVKLPFNAQRIISLSRNDFQSFLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKENLLKERNLILSTLGETKQNLTGLCQQVCKEAALSNEQIQILAKYSSSDCPLYFSFPERERTAPSEGELTAPTTAELVDGLLSVTPTEEQSSCYQRVKGVCDATYDQVQELHPVPVRTLEKTSLVEQCGQSGAITDFCQQMTDKCTTDE", "length": 765 }, "evidence": [ { "id": "E1BJL3", "url": "https://omabrowser.org/oma/group/E1BJL3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ACD2-1", "protein_name": "BTB domain and CNC homolog 1", "gene_name": "Bach1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVSESAVFAYESSVHSTNVLLSLNDQRKKDVLCDVTVLVEGQQFRAHRSVLAACSSYFHSRIVGQTDAELTITLPQEVTVKGFEPLIQFAYTAKLILSKDNVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTSEQQGCARKKCFSSHCQKADFKFSFSEQKDLEIDEADEFFEKKSAQTSHCDSQRCQGNVRASPHLQDSVGPTCQSMCVDKDGALALPSLCPKYRKFQKAFGTDKIRTLESGVRDVHAASVHPKETSELECLGGAQGCADLQVILKCEGMKPAMEREDTKCKDPAPQCPAEQAEVTALSQDSAGPHGLYSLSVLHTYEQSGDVGFPGLQSKTVKTEKPLLGPDAQDEKPLENQELYLKSNMGPKEDSSSLASEDRSSVEREVAEHLAKGFWSDICSTDSPCQMQLSSAVAKDGSEQGYSQRRSECPWLGIRISESPEPGQRTFTTLSSVNCPFISTLSSEGCSSNLEIGNYDYVAEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQDCEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKESLLKERDHILSTLGETKQNLTGLCQQVCKEAALSPEQIQILAKYSASDCPLSFLISEKGKSTPDGELPFTSVFSVSDMPPTAPPPCGRGSTAARQELVQESQPTTTATPEQATLLEPCRQSAGISDFCQQMSDKCTTDE", "length": 739 }, "evidence": [ { "id": "E1BJL3", "url": "https://omabrowser.org/oma/group/E1BJL3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14867-1", "protein_name": "Transcription regulator protein BACH1", "gene_name": "BACH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEPLIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLENKNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGGVPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDVQEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESPEPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQSEKESLLKERDHILSTLGETKQNLTGLCQKVCKEAALSQEQIQILAKYSAADCPLSFLISEKDKSTPDGELALPSIFSLSDRPPAVLPPCARGNSEPGYARGQESQQMSTATSEQAGPAEQCRQSGGISDFCQQMTDKCTTDE", "length": 736 }, "evidence": [ { "id": "E1BJL3", "url": "https://omabrowser.org/oma/group/E1BJL3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97302-1", "protein_name": "Transcription regulator protein BACH1", "gene_name": "Bach1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVSESAVFAYESSVHSTNVLLSLNDQRKKDVLCDVTVLVEGQRFRAHRSVLAACSSYFHSRIVGQTDAELTVTLPEEVTVKGFEPLIQFAYTAKLILSKDNVDEVCRCVEFLSVHNIEESCFQFLKFKFLDSTSEQQECARKKCFSSHCQKADFKFSFSEQKDLEIDEADEFLEKKRVQTPQCDSRRCQGSVKASPPLQDSVSQACQSLCTDKDGALALPSLCPKYRKFQKAFGTDKIRTLESGVRDVHTASVQPNETSELECFGGAQGCADLHVILKCEGMKAAMESEDTEGQDPSPQCPAEQPQGTPLPQDSAGPHGLYSLSALHTYEQSGDVAFAGVQSKTVKTEKPLSRPDAQDEKPSENQDLYLKSSMGPKEDSSSLASEDRSSVEREVAEHLAKGFWSDICSTDSPCQMQLSPTVAKDGPEQGYSQRRSECPWLGIRISESPEPGQRTFTTLSSVNCPFISTLSSEGCSSNLEIGNYDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQDCEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQSEKESLLKERDHILSTLGETKQNLTGLCQQVCKEAALSPEQIQILAKYSASDCPLSFLISEKGKSTPDGELAFTSVFSVSDVPPTAPPPCGRGSSAASQELVQESPPTTAAAPEQATLLEPCRQSAGISDFCQQMSDKCTTDE", "length": 739 }, "evidence": [ { "id": "E1BJL3", "url": "https://omabrowser.org/oma/group/E1BJL3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" }, { "name": "ligand-modulated transcription factor activity", "id": "GO:0098531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098531", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BJL3", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJL3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 741, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJL3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJL3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 100, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJL3" }, { "id": "PS50217", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 563, "end_pos": 621, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 343, "end_pos": 345 }, { "start_pos": 617, "end_pos": 619 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"MKLLLLCLGLTLVCAQEGNSDVVRSNFDIPEIAGEWYSILLASDNREKIEENGSMRVFVEYIDVLENSSLLFKFHTKVNGVCTELSLVSDSTGEDGVFTISYDGENKFRILQVNYSQHIIFYLENFSNSFKLLELYAREPDTSPELKSEFVEICQKYGVVKENVIDLTKVDRCLQERGNGVA", "length": 182, "header": "tr|E1BJP1-1|E1BJP1_BOVIN Isoform 1 of Lipocalin/cytosolic fatty-acid binding domain-containing protein OS=Bos taurus OX=9913 GN=LOC513329 PE=3 SV=2 CANONICAL=E1BJP1-1" }, "isoforms": [ { "isoform_ac": "E1BJP1-1", "url": "https://www.uniprot.org/uniprotkb/E1BJP1/entry#E1BJP1-1", "sequence": { "sequence": "MKLLLLCLGLTLVCAQEGNSDVVRSNFDIPEIAGEWYSILLASDNREKIEENGSMRVFVEYIDVLENSSLLFKFHTKVNGVCTELSLVSDSTGEDGVFTISYDGENKFRILQVNYSQHIIFYLENFSNSFKLLELYAREPDTSPELKSEFVEICQKYGVVKENVIDLTKVDRCLQERGNGVA", "length": 182, "header": "tr|E1BJP1-1|E1BJP1_BOVIN Isoform 1 of Lipocalin/cytosolic fatty-acid binding domain-containing protein OS=Bos taurus OX=9913 GN=LOC513329 PE=3 SV=2 CANONICAL=E1BJP1-1" }, "locus": { "chromosome": "8", "start_pos": 102207049, "end_pos": 102203233, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024598.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024598.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024598.5", "url": "https://www.ensembl.org/id/ENSBTAP00000024598.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:513329", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513329", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FJ50-1", "protein_name": "Major urinary protein 20", "gene_name": "LOC100772566", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKLLLLLLLVLGLELILVCVHAEGKTGLIGKNFNPEKIKGKWYTIGLASDKREKIEEQGSMRVFVEYIRVFENSSLAFKFHTIVNGECTELYVVCDKTAEDGEYEVEYDGSNRFTILDTDYDDYIIIHLKNIKNGKKFQLMELYGRKPELSSNIKEKFEELSKKHGIVKENILDLTEADRCLQARDGEKA", "length": 190 }, "evidence": [ { "id": "E1BJP1", "url": "https://omabrowser.org/oma/group/E1BJP1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SN92-1", "protein_name": "Salivary lipocalin", "gene_name": "SAL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLLFLLCLGLTLASSHKEAGQDVVTSNFDASKIAGEWYSILLASDAKENIEENGSMRVFVEHIRVLDNSSLAFKFQRKVNGECTDFYAVCDKVGDGVYTVAYYGENKFRLLEVNYSDYVILHLVNVNGDKTFQLMEFYGRKPDVEPKLKDKFVEICQQYGIIKENIIDLTKIDRCFQLRGSGGVQESSAE", "length": 191 }, "evidence": [ { "id": "E1BJP1", "url": "https://omabrowser.org/oma/group/E1BJP1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P11590-1", "protein_name": "Major urinary protein 4", "gene_name": "Mup4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLLLCLGLTLVCIHAEEATSKGQNLNVEKINGEWFSILLASDKREKIEEHGSMRVFVEHIHVLENSLAFKFHTVIDGECSEIFLVADKTEKAGEYSVMYDGFNTFTILKTDYDNYIMFHLINEKDGKTFQLMELYGRKADLNSDIKEKFVKLCEEHGIIKENIIDLTKTNRCLKARE", "length": 178 }, "evidence": [ { "id": "E1BJP1", "url": "https://omabrowser.org/oma/group/E1BJP1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BJP1", "url": "https://www.uniprot.org/uniprotkb/E1BJP1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "small molecule binding", "id": "GO:0036094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036094", "evidence": [ { "database": "UniProtKB", "id": "E1BJP1", "url": "https://www.uniprot.org/uniprotkb/E1BJP1" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "E1BJP1", "url": "https://www.uniprot.org/uniprotkb/E1BJP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJP1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 182, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJP1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJP1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJP1" }, { "id": "PF00061", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipocalin/cytosolic fatty-acid binding", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 170, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 125, "end_pos": 127 }, { "start_pos": 52, "end_pos": 54 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJP5-1", "uniprot_ac": "E1BJP5", "uniprot_id": "E1BJP5_BOVIN", "mass": { "chemical_mass": 55013.0, "monoisotopic_mass": 55013.0 }, "refseq": { "ac": "NP_001192413", "name": "heparan-sulfate 6-O-sulfotransferase 3 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192413" }, "gene_names": [ { "name": "HS6ST3", "type": "recommended", "evidence": [ { "id": "E1BJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJP5" } ] }, { "name": "HS6ST3", "type": "synonym", "evidence": [ { "id": "NP_001192413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192413" } ] } ], "protein_names": [ { "name": "Heparan-sulfate 6-O-sulfotransferase", "type": "recommended", "evidence": [ { "id": "E1BJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJP5/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "E1BJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJP5/entry#names_and_taxonomy" } ] }, { "name": "heparan-sulfate 6-O-sulfotransferase 3 precursor", "type": "synonym", "evidence": [ { "id": "NP_001192413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192413" } ] } ], "function": [ { "annotation": "6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.", "evidence": [ { "database": "UniProtKB", "id": "E1BJP5", "url": "https://www.uniprot.org/uniprotkb/E1BJP5#function" }, { "database": "UniProtKB", "id": "RU364122", "url": "https://www.uniprot.org/uniprotkb/RU364122#function" }, { "database": "UniProtKB", "id": "ARBA00058023", "url": "https://www.uniprot.org/uniprotkb/ARBA00058023#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJP5", "url": "https://www.uniprot.org/uniprotkb/E1BJP5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HS6ST3", "url": "https://www.uniprot.org/uniprotkb/E1BJP5", "locus": { "chromosome": "12", "start_pos": 74075781, "end_pos": 73363796, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000039065", "url": "https://www.ensembl.org/id/ENSBTAG00000039065" } ] } } ], "crossref": [ { "id": "E1BJP5", "url": "https://alphafold.ebi.ac.uk/entry/E1BJP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000039065", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039065", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538566", "url": "https://www.ncbi.nlm.nih.gov/gene/538566", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538566", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538566", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RKTQYMF", "url": "https://omabrowser.org/oma/group/RKTQYMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJP5", "url": "https://www.orthodb.org/?gene=E1BJP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12812", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12812", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12812:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12812:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022928", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192413", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "56604", "url": "https://www.rhea-db.org/rhea/56604", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BJP5", "url": "https://www.uniprot.org/uniprotkb/E1BJP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJP5-1", "url": "https://www.uniprot.org/uniprotkb/E1BJP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDERFNKWLLTPVLTLLFVVIMYQYVSPSCSSSCANFGEQPRAGEAGQPAAPGPARRAQAPPEDWERRPQLPPPPRGPPEGPRGPAAPEDEDEEPGEPEDEEEEAEEEEEEPDPEAPENGSLPRFVPRFNFTPKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCTYNLANNRQVRMLADLSLVGCYNLTFMNESERNAILLQSAKSNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVEINEGARRRIEELNFLDVQLYEYAKDLFQQRYHRTKQLERQRDRQRRRGERRLQRDHRGHRWPKQEGNPEGAVTEDYNSQVVRW", "length": 473, "header": "tr|E1BJP5-1|E1BJP5_BOVIN Isoform 1 of Heparan-sulfate 6-O-sulfotransferase OS=Bos taurus OX=9913 GN=HS6ST3 PE=3 SV=2 CANONICAL=E1BJP5-1" }, "isoforms": [ { "isoform_ac": "E1BJP5-1", "url": "https://www.uniprot.org/uniprotkb/E1BJP5/entry#E1BJP5-1", "sequence": { "sequence": "MDERFNKWLLTPVLTLLFVVIMYQYVSPSCSSSCANFGEQPRAGEAGQPAAPGPARRAQAPPEDWERRPQLPPPPRGPPEGPRGPAAPEDEDEEPGEPEDEEEEAEEEEEEPDPEAPENGSLPRFVPRFNFTPKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCTYNLANNRQVRMLADLSLVGCYNLTFMNESERNAILLQSAKSNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVEINEGARRRIEELNFLDVQLYEYAKDLFQQRYHRTKQLERQRDRQRRRGERRLQRDHRGHRWPKQEGNPEGAVTEDYNSQVVRW", "length": 473, "header": "tr|E1BJP5-1|E1BJP5_BOVIN Isoform 1 of Heparan-sulfate 6-O-sulfotransferase OS=Bos taurus OX=9913 GN=HS6ST3 PE=3 SV=2 CANONICAL=E1BJP5-1" }, "locus": { "chromosome": "12", "start_pos": 74075778, "end_pos": 73363796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056403.2", "url": "https://www.ensembl.org/id/ENSBTAT00000056403.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048528.2", "url": "https://www.ensembl.org/id/ENSBTAP00000048528.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 279, "start_aa": "Thr", "end_pos": 279, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr279", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:538566", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538566", "resource": "KEGG Pathway" }, { "id": "R-BTA-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZN51-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase", "gene_name": "Hs6st3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDERFNKWLLTPVLTLLFVVIMYQYVSPSCSSSCTNFGEQLRSGEARPPAVPSPARRAQAPPDEWERRPQLPPPPRGPPEGSRGVAAPEDEDEDPGDPEEEEEEEEEPDPEAPENGSLPRFVPRFNFTLKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCSYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVDINDGARQHIEELNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERRLHREHRAHRWPKEDRAIEGTVTEDYNSQVVRW", "length": 469 }, "evidence": [ { "id": "E1BJP5", "url": "https://omabrowser.org/oma/group/E1BJP5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IZP7-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 3", "gene_name": "HS6ST3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDERFNKWLLTPVLTLLFVVIMYQYVSPSCTSSCTNFGEQPRAGEAGPPAVPGPARRAQAPPEEWERRPQLPPPPRGPPEGPRGAAAPEEEDEEPGDPREGEEEEEEDEPDPEAPENGSLPRFVPRFNFSLKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCTYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVEINEGARQRIEDLNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERRLQREHRDHQWPKEDGAAEGTVTEDYNSQVVRW", "length": 471 }, "evidence": [ { "id": "E1BJP5", "url": "https://omabrowser.org/oma/group/E1BJP5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYK4-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 3", "gene_name": "Hs6st3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDERFNKWLLTPVLTLLFVVIMYQYVSPSCTSSCTNFGEQLRSGEARPPAVPSPARRAQAPLDEWERRPQLPPPPRGPPEGSRGVAAPEDEDEDPGDPEEEEEEEEEEPDPEAPENGSLPRFVPRFNFTLKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCSYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVDINDGARQHIEELNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERRLQREHRAHRWPKEDRAMEGTVTEDYNSQVVRW", "length": 470 }, "evidence": [ { "id": "E1BJP5", "url": "https://omabrowser.org/oma/group/E1BJP5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BJP5", "url": "https://www.uniprot.org/uniprotkb/E1BJP5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BJP5", "url": "https://www.uniprot.org/uniprotkb/E1BJP5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "E1BJP5", "url": "https://www.uniprot.org/uniprotkb/E1BJP5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heparan sulfate 6-sulfotransferase activity", "id": "GO:0017095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017095", "evidence": [ { "database": "UniProtKB", "id": "E1BJP5", "url": "https://www.uniprot.org/uniprotkb/E1BJP5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "56604", "name": "", "equation": "alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate = 6-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BJP5-1", "A0AAA9THN1-1", "A0ABI0P2Y5-1" ], "evidence": [ { "id": "56604", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56604" } ] }, { "id": "R-BTA-2076419", "name": "HS6STs sulfate GlcN at C6 in heparan sulfate/heparin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9THN1-1", "E1BJP5-1" ], "evidence": [ { "id": "R-BTA-2076419", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2076419" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9THN1", "gene_name": "HS6ST2", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0AAA9THN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THN1" } ] } ] }, { "uniprot_ac": "A0ABI0P2Y5", "gene_name": "HS6ST1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0ABI0P2Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Y5" } ] } ] }, { "uniprot_ac": "E1BJP5", "gene_name": "HS6ST3", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJP5" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJP5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 473, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJP5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJP5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 279 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 130, "end_pos": 132 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 382, "end_pos": 384 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJV0-1", "uniprot_ac": "E1BJV0", "uniprot_id": "E1BJV0_BOVIN", "mass": { "chemical_mass": 61025.0, "monoisotopic_mass": 61025.0 }, "refseq": { "ac": "NP_001178982", "name": "EH domain-containing protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178982" }, "gene_names": [ { "name": "EHD4", "type": "recommended", "evidence": [ { "id": "E1BJV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ] }, { "name": "EHD4", "type": "synonym", "evidence": [ { "id": "NP_001178982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178982" } ] } ], "protein_names": [ { "name": "EH domain containing 4", "type": "synonym", "evidence": [ { "id": "E1BJV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJV0/entry#names_and_taxonomy" } ] }, { "name": "EH domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "NP_001178982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178982" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EHD4", "url": "https://www.uniprot.org/uniprotkb/E1BJV0", "locus": { "chromosome": "10", "start_pos": 37295624, "end_pos": 37379520, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006792", "url": "https://www.ensembl.org/id/ENSBTAG00000006792" } ] } } ], "crossref": [ { "id": "E1BJV0", "url": "https://alphafold.ebi.ac.uk/entry/E1BJV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006792", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006792", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505206", "url": "https://www.ncbi.nlm.nih.gov/gene/505206", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031692", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031692", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505206", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505206", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISAKKEM", "url": "https://omabrowser.org/oma/group/ISAKKEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJV0", "url": "https://www.orthodb.org/?gene=E1BJV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18150", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18150", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178982", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJV0-1", "url": "https://www.uniprot.org/uniprotkb/E1BJV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSWLGRQAGGRGGTGADPVQTVTGGLRSLYQRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGNTPGNALVVDPKKPFRKLGRFGNAFLNRFMCSQLPNEVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWTQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISFLKKEMPSMFGKENKKRELISRLPEIYIQLQREYHISAGDFPKVKAMQEKLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMNLISQEEMSMPPPLVQGGAFDGTAESPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGINAKKEMVTSKLPNSVLGKIWKLADCDGDGMLDEEEFALAKHLIKIKLSGYELPSSLPPHLVPPSHRKSLSKAD", "length": 540, "header": "tr|E1BJV0-1|E1BJV0_BOVIN Isoform 1 of EH domain containing 4 OS=Bos taurus OX=9913 GN=EHD4 PE=4 SV=1 CANONICAL=E1BJV0-1" }, "isoforms": [ { "isoform_ac": "E1BJV0-1", "url": "https://www.uniprot.org/uniprotkb/E1BJV0/entry#E1BJV0-1", "sequence": { "sequence": "MFSWLGRQAGGRGGTGADPVQTVTGGLRSLYQRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGNTPGNALVVDPKKPFRKLGRFGNAFLNRFMCSQLPNEVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWTQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISFLKKEMPSMFGKENKKRELISRLPEIYIQLQREYHISAGDFPKVKAMQEKLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMNLISQEEMSMPPPLVQGGAFDGTAESPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGINAKKEMVTSKLPNSVLGKIWKLADCDGDGMLDEEEFALAKHLIKIKLSGYELPSSLPPHLVPPSHRKSLSKAD", "length": 540, "header": "tr|E1BJV0-1|E1BJV0_BOVIN Isoform 1 of EH domain containing 4 OS=Bos taurus OX=9913 GN=EHD4 PE=4 SV=1 CANONICAL=E1BJV0-1" }, "locus": { "chromosome": "10", "start_pos": 37379424, "end_pos": 37296088, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008933.6", "url": "https://www.ensembl.org/id/ENSBTAT00000008933.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008933.4", "url": "https://www.ensembl.org/id/ENSBTAP00000008933.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505206", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505206", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B3LF48-1", "protein_name": "EH domain-containing protein 2", "gene_name": "EHD2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "METSSTISIGSCLKEHQKIYKEWFNIADSDGDGRVSGNDATKFFAMSKLSRQELKQVWAVADSKRQGFLGLSEFITAMKLVSLAQEGHEITSDLLKGSIDMKSVELPVLEGLENVVSKQKVSKTNVDVEDNVVTKPQVTAKTPWFKSKSIIKPQVNVVTIVDGLKRLYTEKLKPLEVTYRFNDFASPVLTSSDFDAKPMVMLLGQYSTGKTTFIKHLLGCDYPGAHIGPEPTTDRFVVAMSGPDERTIPGNTMAVQADMPFNGLTSFGGAFLSKFECSQMPHPVLDQITLVDTPGVLSGEKQRMQRSYDFTGVISWFASKCDMILLLFDPHKLDISDEFKRVITSLRGNEDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVLNTPEVVRVYIGSFNDKPINEVAVGPIGKELFEKEQNDLLADLMDVPKKACDRKINEFVKRARSAKINAYIMSHLKKEMPAMMGKSKAQQRLMDNLEEEFGKVQREFHLPAGDFPSVEHFREVLGGYNIDKFEKLKPKMIQAVDDMLGYDIPDLLKKFRNPYDN", "length": 546 }, "evidence": [ { "id": "E1BJV0", "url": "https://omabrowser.org/oma/group/E1BJV0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F1NV47-1", "protein_name": "EH domain containing 4", "gene_name": "EHD4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFSWLGKQGGGRERGVGGSDVVQTVTGGLRDLYLRKLLPLEEHYRFHEFHSPALEEADFENKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGESEGSVPGNALVVDPKKPFRKLSRFGNAFLNRFLCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLRNTENRRLFEAEAQDLFQDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPTMFGKENKKKELISRLPEIYSQLQREYHISAGDFPEVRKMQEQLEMCDFTKFHSLKPKLIEAVDNMLANKIASLMNLITQEESNMPTEMVHGGAFDGTMAGPFGQGYGEGAKEGADEDEWVVAKDKPAYDEIFYTLSPINGKISGINAKKEMVTSKLPNSVLGKIWKLADCDGDGMLDEEEFALAKHLIKIKLDGYELPGTLPPHLVPPSHRKPLQTAE", "length": 542 }, "evidence": [ { "id": "E1BJV0", "url": "https://omabrowser.org/oma/group/E1BJV0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LDA5-1", "protein_name": "EH domain containing 4", "gene_name": "EHD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSSKISSLMSLISQEEMSMPTQLVQGGAFDGTAEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPVNGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLQKAD", "length": 541 }, "evidence": [ { "id": "E1BJV0", "url": "https://omabrowser.org/oma/group/E1BJV0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8R3Z7-1", "protein_name": "EH-domain containing 4", "gene_name": "Ehd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRKDLRSLLNNERAPVTQRLMIGRCGRGRARERAVARASPAPRVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSMFGKENKKRELIFRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMSLISQEEMNMPTQMVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLPKAD", "length": 549 }, "evidence": [ { "id": "E1BJV0", "url": "https://omabrowser.org/oma/group/E1BJV0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9EQP2-1", "protein_name": "EH domain-containing protein 4", "gene_name": "Ehd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWMGRQAGGRERSGGMDAVQTVTGGLRSLYQRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPNMFGKENKKRELIYRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMGLISQEEMNMPTQMVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLPKAD", "length": 541 }, "evidence": [ { "id": "E1BJV0", "url": "https://omabrowser.org/oma/group/E1BJV0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H223-1", "protein_name": "EH domain-containing protein 4", "gene_name": "EHD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPKAD", "length": 541 }, "evidence": [ { "id": "E1BJV0", "url": "https://omabrowser.org/oma/group/E1BJV0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" }, { "name": "cell migration involved in sprouting angiogenesis", "id": "GO:0002042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002042", "evidence": [ { "database": "UniProtKB", "id": "E1BJV0", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BJV0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 540, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BJV0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BJV0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" }, { "id": "PS51718", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51718" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dynamin-type G", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 288, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 478, "end_pos": 513, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BJV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJV0" }, { "id": "PS50031", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50031" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EH", "eco_id": "ECO_0000259", "start_pos": 446, "end_pos": 534, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BJW3-1", "uniprot_ac": "E1BJW3", "uniprot_id": "E1BJW3_BOVIN", "mass": { "chemical_mass": 103612.0, "monoisotopic_mass": 103612.0 }, "refseq": { "ac": "XP_002698984", "name": "multimerin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698984" }, "gene_names": [ { "name": "MMRN2", "type": "recommended", "evidence": [ { "id": "E1BJW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJW3" } ] }, { "name": "MMRN2", "type": "synonym", "evidence": [ { "id": "XP_002698984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698984" } ] } ], "protein_names": [ { "name": "Multimerin-2", "type": "recommended", "evidence": [ { "id": "E1BJW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJW3/entry#names_and_taxonomy" } ] }, { "name": "multimerin-2", "type": "synonym", "evidence": [ { "id": "XP_002698984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698984" } ] } ], "function": [ { "annotation": "Extracellular matrix protein that plays significant roles in the vascular system and is required for the maintenance and stability of blood vessel. Affects several essential steps in angiogenesis including endothelial cell proliferation, migration, and tube formation. Positively regulates angiogenesis by acting as a ligand for CD93 receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3#function" }, { "database": "UniProtKB", "id": "ARBA00054312", "url": "https://www.uniprot.org/uniprotkb/ARBA00054312#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MMRN2", "url": "https://www.uniprot.org/uniprotkb/E1BJW3", "locus": { "chromosome": "28", "start_pos": 41553851, "end_pos": 41570018, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003510", "url": "https://www.ensembl.org/id/ENSBTAG00000003510" } ] } } ], "crossref": [ { "id": "E1BJW3", "url": "https://alphafold.ebi.ac.uk/entry/E1BJW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003510", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003510", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "512308", "url": "https://www.ncbi.nlm.nih.gov/gene/512308", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512308", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512308", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFSNHMS", "url": "https://omabrowser.org/oma/group/EFSNHMS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJW3", "url": "https://www.orthodb.org/?gene=E1BJW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5173105", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5173105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002698984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698984", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJW3-1", "url": "https://www.uniprot.org/uniprotkb/E1BJW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MILTLLFGLGGPLGWGMLGTWAQAPGTSFSDPHSPQPPGVWRAEAEDSSGDPVRRNWCPYQKSRLVTFIAACKTEKFLVHSQQPCPQGAPNCQKVKVMYRVAHKPVYQVKQKVLASVAWRCCPGFAGPDCQHHDPMAIPEPEDPGDSLQEPWDGPVDFESGHPAAEIRSTVERQERRLGDLQNDIHQMADSLPGLWEAWASNLTVATTEANQTELEFPGRALEQVLLPHINTFLQGHLSPMWRSFNQSLHSLSQVIRNLSLDVEANQQALKRVQESSVARADFQELGTKFETKVQENAQRVGQLRQDVEDRLHAQRLSLHQSLSEVQTDVDIKLKKLLKAQESVGINSSLVLAAAGAAARPEPESLNARLGQLQRNLSALHVATAHREEALRSTLADMKATLARHVDEIKELYSESDDTFDEISKLQRQVQELEVNHTALRELRVILMEKSLIMEENKEDMERQLLELNLTLQHLQGAHADLIKYVKDCNCQKLYFDLDVIREDQRDTTRALEETQVTLDERRQQDGSSLQALRDTVASLSLAVDTQQAEGERARAEAARLRSQLRALGGEVSALQAAETEIRRDIRQLHSSFSALLEDALRHEAVLAALFGEEVMEEMSEEGPGTLPLRYEQIRVALMDAASGLQEQALGWDALAARVTALEQASGTRRQTARLEPSRAASPEEVGGLAQELQRLSSDLERVGRCCEASWVSSLNSSLEGLRGELSTTERGLERHQRLFHSLFGNFQGLVAANVSLDLQKLQAMLNRKGKKQQKGLEAPKRRDRKQVESLEDARVKGPALWEAGSPVAFYASFSEGTTALQTVKFNTAYINVGSSYFPEHGYFRAPERGVYLFAVSIEFGPGPGTGQLVFGGHHRTPVYTTEEQRGGSPATTFAMAELQKGERVWFELTQGSIMKRSPPGTAFGGFLMFKT", "length": 932, "header": "tr|E1BJW3-1|E1BJW3_BOVIN Isoform 1 of Multimerin-2 OS=Bos taurus OX=9913 GN=MMRN2 PE=4 SV=2 CANONICAL=E1BJW3-1" }, "isoforms": [ { "isoform_ac": "E1BJW3-1", "url": "https://www.uniprot.org/uniprotkb/E1BJW3/entry#E1BJW3-1", "sequence": { "sequence": "MILTLLFGLGGPLGWGMLGTWAQAPGTSFSDPHSPQPPGVWRAEAEDSSGDPVRRNWCPYQKSRLVTFIAACKTEKFLVHSQQPCPQGAPNCQKVKVMYRVAHKPVYQVKQKVLASVAWRCCPGFAGPDCQHHDPMAIPEPEDPGDSLQEPWDGPVDFESGHPAAEIRSTVERQERRLGDLQNDIHQMADSLPGLWEAWASNLTVATTEANQTELEFPGRALEQVLLPHINTFLQGHLSPMWRSFNQSLHSLSQVIRNLSLDVEANQQALKRVQESSVARADFQELGTKFETKVQENAQRVGQLRQDVEDRLHAQRLSLHQSLSEVQTDVDIKLKKLLKAQESVGINSSLVLAAAGAAARPEPESLNARLGQLQRNLSALHVATAHREEALRSTLADMKATLARHVDEIKELYSESDDTFDEISKLQRQVQELEVNHTALRELRVILMEKSLIMEENKEDMERQLLELNLTLQHLQGAHADLIKYVKDCNCQKLYFDLDVIREDQRDTTRALEETQVTLDERRQQDGSSLQALRDTVASLSLAVDTQQAEGERARAEAARLRSQLRALGGEVSALQAAETEIRRDIRQLHSSFSALLEDALRHEAVLAALFGEEVMEEMSEEGPGTLPLRYEQIRVALMDAASGLQEQALGWDALAARVTALEQASGTRRQTARLEPSRAASPEEVGGLAQELQRLSSDLERVGRCCEASWVSSLNSSLEGLRGELSTTERGLERHQRLFHSLFGNFQGLVAANVSLDLQKLQAMLNRKGKKQQKGLEAPKRRDRKQVESLEDARVKGPALWEAGSPVAFYASFSEGTTALQTVKFNTAYINVGSSYFPEHGYFRAPERGVYLFAVSIEFGPGPGTGQLVFGGHHRTPVYTTEEQRGGSPATTFAMAELQKGERVWFELTQGSIMKRSPPGTAFGGFLMFKT", "length": 932, "header": "tr|E1BJW3-1|E1BJW3_BOVIN Isoform 1 of Multimerin-2 OS=Bos taurus OX=9913 GN=MMRN2 PE=4 SV=2 CANONICAL=E1BJW3-1" }, "locus": { "chromosome": "28", "start_pos": 41569819, "end_pos": 41554855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004563.5", "url": "https://www.ensembl.org/id/ENSBTAT00000004563.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004563.4", "url": "https://www.ensembl.org/id/ENSBTAP00000004563.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512308", "resource": "KEGG Pathway" }, { "id": "R-BTA-5173105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5173105", "resource": "Reactome", "description": "O-linked glycosylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QGH7-1", "protein_name": "Multimerin-2", "gene_name": "Mmrn2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MILTLMLGLGGCLGWGLLGAWAQDPGTRFPDPKRPRVPTGWKIEAEDTSGDPIGRNWCPYQKSRLVTFVAACKTEKFLVHSQQPCPQGSPDCQRVKVMYRVAQKPVYQIQQKVLISVAWRCCPGFQGPDCQDYDPTANPGPTELSGELPETWDQLNGFELGHPVTEFNDIQVPQEQQEHLLQDLQNDAQLVEDGLPGPWETPASNLTVETAEANQTEFEFAGRMSAHLLQAHINAFLQAHFSPTLKSFSESLHSLSQAVRNLSLDVEANHQAVKMVQESTVTGTELQELGAKFDAKIQENNQRVSQLWQDVEDQLHAQRRSVHHALSEIQAEVSTKLKQLVKAHELPGANGSLAVASAARPEPESLQARLGQLQRNMSALHAVIDWREEELQSTLKKMDSVLKRHVDEIKELYSESDETFDQISKVERQVEELLVNHTGLRELRVMLIEKSLIMEENKEEMQRQLLELNLTLQHLQVGHADLIKYVKDCNCQRLYSEVDVIREGQRDTMHTLEETQVSLDVQHQLDGSLQALQSTVDAMSSTMDEHKGEGERARAERARMRSQLRALDHAVEALKAVANQTSREMRQLHSSFAALLEDALRHQAMLNALFGEEMMEEMLEEVPRPLPLNYEQIRVSLQDAARVLQEQASGWNTLASRVQALEKALEHHPQLAERLQPSHDSGTAEEATALANLEQEIQRLSSNVKQVGQCCEASWAAPLNGSLEDLHSMLSDTRYSLRQHQQLFHGLFQNFQELVASNISLDLGKLQAMLSKKEKKQQKGLETSRKREKKQVVMSADAHAKRMAKGALDSELWEADSPVAFYASSSEAATALQMVKFNTTSINVGSSYFPEHGYFRAPKHGIYLFAVSITFGPGPSMGQLVFEGHHRVPVYSTEQRGGSTATTFALAELQKGKRVWFELIQGSVTKGSQPHTAFGGLLIFKT", "length": 942 }, "evidence": [ { "id": "E1BJW3", "url": "https://omabrowser.org/oma/group/E1BJW3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6GHU7-1", "protein_name": "Multimerin-2", "gene_name": "Mmrn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLAGWAGPGHFLPLLSLCFLFFLTFCLKTTSPANSGVTCKAEPQHRQLSLPLTMILTLLLGLAGYLSWGLLGSWAQDPGSRFSNPNRLSVPEGWRIGADDDTSRDPSQRTTKWTPLPERGLFHPAIFFPSRLLESQLPRRQGQGIVATGIFWNWCPYQKSRLVTFVAACKTEKFLVHSQQPCPQGAPDCQRVKVMYRVAQKPVYQVQQKVLMSVDWRCCPGFQGPDCQDHHPTANPEPTEASGKLQETWDSLDGFEPGHPVTEFNEIKAPQEHLLQNLQNDAQPVEDGFAGPWEAPSSNLTAAMTEANLTEFESLGRTSKHLLQPHIHAFLEAHFSPIWKSFNESLQSLFQAIRNLSLDVEANHRAIKMIQEGTVARADFRELGAKFEAKVQQNSQRLGQLWQDVEDQLHAQRRSVHHALSEVQAEVSTKLKQLVKAQELPGANGSLAVASAARPEPESLQARLGQLQRNLSALHMVTNQREEELRGTLKDMDSVLRQHTDEIKELYSESDETFDQISKVERQVEELLVNHTGLRELRVILMEKSLIMEENKEEMERQLLDLNLTLQHLQAAHADLIKYVKDCNCRRVYSDMDVIPEGRRDAMHTLEETQVSPDEQHQLDGSLQALQSTVDAMSSALDAYRGEGERARAERARMRSQLRALDHAVEALKTAANGTRKEIRLLHGSFAALLEDALRHQAVLAALFGEEMVDEMSEEPPRPLPLNYEQIRLALQDAASGLQEQAVGWEDLATRVEALEKAAGGFVEQHPRSAEGLEPSHDFGREEDTRALGDLEQEIQRLSSDVKQMGQCCEASWALNGSLEDLHSALSDTQHSLRQHQQLFRGLFHNFQGLLASNTSLDLDKLQAMLSKKDKKQQKGPGESRKRDKKQVVMSADAKGLGLWEAGSPVAFYASSSEEATALQMVKFNATSVNVGSGYFPEHGYFRAPKRGIYLFAVSVTFGPGPGMGQLVFEGHRRVPVYSAEQRGGSTATTFAMAELQKGERVWFELIQGSVTKGSRPGTAFGGFLMFKT", "length": 1030 }, "evidence": [ { "id": "E1BJW3", "url": "https://omabrowser.org/oma/group/E1BJW3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6H6E2-1", "protein_name": "Multimerin-2", "gene_name": "Mmrn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPTLLLGFGVYLSWGLLGSWAQDPGTKFSHLNRPGMPEGWRLGAEDTSRDPIRRNWCPYQKSRLVTFVAACKTEKFLVHSQQPCPQGAPDCQGVRVMYRVAQKPVYQVQQKVLISVDWRCCPGFQGPDCQDHNPTANPEPTEPSGKLQETWDSMDGFELGHPVPEFNEIKVPQEQQENLLQNLQNDAQSVEDGFPGSWEAPPSNLTDEMTEANLTEFEFPGRTSEHLLQPHIDAFLKAHFSPIWKNFNDSLHSLSQAIRNLSLDVEANHQAIKMIQEGTVARADFQELGAKFEAKVQQNSQRLGQLWQDVEDQLHAQRRSVHHALSDVQAEVSTKLKQLVKAQELPGANGSLVMASAAAAARPEPESLQARLGQLQRNLSALHMVTSQREEELQSTLKNMDSVLKQHAEEIKELYSESDETFDQISKVERQVEELLVNHTGLRELRVILMEKSLIMEENKEEIERQLLELNLTLQHLHAGHADLIKYVKDCNCQRVNSDVDVAPEGHRDVMHTLEETQVSLDEQHQLDGSSLQALQSTVDAMSSAMDAYRGEGERARAERARIRSQLRALDHAVEALKTAANGTRKEIRLLHGSFTALLEDALRHQAVLAALFGEEMIDEMSEEAPRPLPLDYEQIRLALQDAASGLQEQAIGWEDLATRVEALEKAAGGFVEQHPQLAEGLEPSHDSGREEEAMTLAELEQEIRRLSSDVKQIGQCCEASWAASLNSSLEDLHSMLLDTQHGLRQHRQLFHNLFQNFQGLVASNISLDLGKLQAMLSKKDKKQPRGPGESRKRDKKQVVMSTDAHAKGLELWETGSPVAFYAGSSEGATALQMVKFNTTSINVGSSYFPEHGYFRAPKRGVYLFAVSITFGPGPGMGQLVFEGHHRVPVYSTEQRGGSTATTFAMVELQKGERAWFELIQGSATKGSQPGTAFGGFLMFKT", "length": 943 }, "evidence": [ { "id": "E1BJW3", "url": "https://omabrowser.org/oma/group/E1BJW3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8L6-1", "protein_name": "Multimerin-2", "gene_name": "MMRN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MILSLLFSLGGPLGWGLLGAWAQASSTSLSDLQSSRTPGVWKAEAEDTGKDPVGRNWCPYPMSKLVTLLALCKTEKFLIHSQQPCPQGAPDCQKVKVMYRMAHKPVYQVKQKVLTSLAWRCCPGYTGPNCEHHDSMAIPEPADPGDSHQEPQDGPVSFKPGHLAAVINEVEVQQEQQEHLLGDLQNDVHRVADSLPGLWKALPGNLTAAVMEANQTGHEFPDRSLEQVLLPHVDTFLQVHFSPIWRSFNQSLHSLTQAIRNLSLDVEANRQAISRVQDSAVARADFQELGAKFEAKVQENTQRVGQLRQDVEDRLHAQHFTLHRSISELQADVDTKLKRLHKAQEAPGTNGSLVLATPGAGARPEPDSLQARLGQLQRNLSELHMTTARREEELQYTLEDMRATLTRHVDEIKELYSESDETFDQISKVERQVEELQVNHTALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQGGHADLIKYVKDCNCQKLYLDLDVIREGQRDATRALEETQVSLDERRQLDGSSLQALQNAVDAVSLAVDAHKAEGERARAATSRLRSQVQALDDEVGALKAAAAEARHEVRQLHSAFAALLEDALRHEAVLAALFGEEVLEEMSEQTPGPLPLSYEQIRVALQDAASGLQEQALGWDELAARVTALEQASEPPRPAEHLEPSHDAGREEAATTALAGLARELQSLSNDVKNVGRCCEAEAGAGAASLNASLHGLHNALFATQRSLEQHQRLFHSLFGNFQGLMEANVSLDLGKLQTMLSRKGKKQQKDLEAPRKRDKKEAEPLVDIRVTGPVPGALGAALWEAGSPVAFYASFSEGTAALQTVKFNTTYINIGSSYFPEHGYFRAPERGVYLFAVSVEFGPGPGTGQLVFGGHHRTPVCTTGQGSGSTATVFAMAELQKGERVWFELTQGSITKRSLSGTAFGGFLMFKT", "length": 949 }, "evidence": [ { "id": "E1BJW3", "url": "https://omabrowser.org/oma/group/E1BJW3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of cell migration involved in sprouting angiogenesis", "id": "GO:0090051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090051", "evidence": [ { "database": "UniProtKB", "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3" } ], "pmid": "" }, { "name": "negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "id": "GO:1903588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903588", "evidence": [ { "database": "UniProtKB", "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3" } ], "pmid": "" }, { "name": "negative regulation of vascular endothelial growth factor receptor signaling pathway", "id": "GO:0030948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030948", "evidence": [ { "database": "UniProtKB", "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3" } ], "pmid": "" }, { "name": "positive regulation of defense response to bacterium", "id": "GO:1900426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900426", "evidence": [ { "database": "UniProtKB", "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3" } ], "pmid": "" }, { "name": "cell migration involved in sprouting angiogenesis", "id": "GO:0002042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002042", "evidence": [ { "database": "UniProtKB", "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3" } ], "pmid": "" }, { "name": "positive regulation of epithelial tube formation", "id": "GO:1905278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905278", "evidence": [ { "database": "UniProtKB", "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "E1BJW3", "url": "https://www.uniprot.org/uniprotkb/E1BJW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK11/entry#names_and_taxonomy" } ] }, { "name": "Cyclosome subunit 5", "type": "synonym", "evidence": [ { "id": "E1BK11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK11/entry#names_and_taxonomy" } ] }, { "name": "anaphase-promoting complex subunit 5", "type": "synonym", "evidence": [ { "id": "NP_001179874", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179874" } ] } ], "function": [ { "annotation": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.", "evidence": [ { "database": "UniProtKB", "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11#function" }, { "database": "UniProtKB", "id": "ARBA00045696", "url": "https://www.uniprot.org/uniprotkb/ARBA00045696#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ANAPC5", "url": "https://www.uniprot.org/uniprotkb/E1BK11", "locus": { "chromosome": "17", "start_pos": 53862505, "end_pos": 53827416, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003092", "url": "https://www.ensembl.org/id/ENSBTAG00000003092" } ] } } ], "crossref": [ { "id": "E1BK11", "url": "https://alphafold.ebi.ac.uk/entry/E1BK11", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003092", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003092", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16270", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16270", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540537", "url": "https://www.ncbi.nlm.nih.gov/gene/540537", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540537", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540537", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DANMGMA", "url": "https://omabrowser.org/oma/group/DANMGMA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BK11", "url": "https://www.orthodb.org/?gene=E1BK11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12830", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12830", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12830:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12830:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-174048", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-174084", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174084", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-174154", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174154", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-174178", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-174184", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174184", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-176407", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-176408", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-176409", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-176412", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176412", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-179409", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-179409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2559582", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2559582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-68867", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-68867", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-69017", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69017", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179874", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179874", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK11-1", "url": "https://www.uniprot.org/uniprotkb/E1BK11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMGRTGEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTMEDADMELASREEGERKMEKEELDVSIREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLIHCQRTRNTEMVISVLLSVAELYWRSSSPTIALPVLLQALALSKEYRLQHLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAVLDKGRAMFLVAKCQVASAASCEPLKKAEALEAAIENLNEAKNYFAKVDCKEQIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQDLPFHGVPLINLL", "length": 755, "header": "tr|E1BK11-1|E1BK11_BOVIN Isoform 1 of Anaphase-promoting complex subunit 5 OS=Bos taurus OX=9913 GN=ANAPC5 PE=3 SV=1 CANONICAL=E1BK11-1" }, "isoforms": [ { "isoform_ac": "E1BK11-1", "url": "https://www.uniprot.org/uniprotkb/E1BK11/entry#E1BK11-1", "sequence": { "sequence": "MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMGRTGEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTMEDADMELASREEGERKMEKEELDVSIREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLIHCQRTRNTEMVISVLLSVAELYWRSSSPTIALPVLLQALALSKEYRLQHLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAVLDKGRAMFLVAKCQVASAASCEPLKKAEALEAAIENLNEAKNYFAKVDCKEQIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQDLPFHGVPLINLL", "length": 755, "header": "tr|E1BK11-1|E1BK11_BOVIN Isoform 1 of Anaphase-promoting complex subunit 5 OS=Bos taurus OX=9913 GN=ANAPC5 PE=3 SV=1 CANONICAL=E1BK11-1" }, "locus": { "chromosome": "17", "start_pos": 53862267, "end_pos": 53827517, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004025.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004025.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004025.5", "url": "https://www.ensembl.org/id/ENSBTAP00000004025.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540537", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540537", "resource": "KEGG Pathway" }, { "id": "R-BTA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-BTA-174048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174048", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Cyclin B" }, { "id": "R-BTA-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-BTA-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-BTA-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-BTA-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-BTA-176407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176407", "resource": "Reactome", "description": "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" }, { "id": "R-BTA-176408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176408", "resource": "Reactome", "description": "Regulation of APC/C activators between G1/S and early anaphase" }, { "id": "R-BTA-176409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176409", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of mitotic proteins" }, { "id": "R-BTA-176412", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176412", "resource": "Reactome", "description": "Phosphorylation of the APC/C" }, { "id": "R-BTA-179409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-179409", "resource": "Reactome", "description": "APC-Cdc20 mediated degradation of Nek2A" }, { "id": "R-BTA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-BTA-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-BTA-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-BTA-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LDW9-1", "protein_name": "Anaphase-promoting complex subunit 5", "gene_name": "Anapc5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMTNGVVHANLFGIKDWVTPYKIAVLVLLNEMGRTGEGAVSLVERRKLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMDREDAERQMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQAALLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAEGKSNGDEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRADSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESVNAGVQQNNTESFAVALCHLAELHAEQGCFAAAAEVLKHLRERFPPNSQHAQLWMLCDQKIQFDRAMNDGKFHLADSLVTGITALNGIEGVYRKAVVMQAQNQMTEAHKLLQKLLTYCQKLKNTEMVISVLLSVAELYWRSSSPTIAMPVLLEALALSKEYRLQYLASETVLNLAYAQLILGIPEQALTLLHMAIEPILADGAILDKGRAMFLVSKCQVASAASYDPVKKAEALEAAIENLNEAKNYFAKVDCRERIRDVAYFQARLYHALGKTQERNRCAMIFRQLHQELPSHGVPLINHL", "length": 740 }, "evidence": [ { "id": "E1BK11", "url": "https://omabrowser.org/oma/group/E1BK11/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A1L1K3-1", "protein_name": "Anaphase-promoting complex subunit 5", "gene_name": "Anapc5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMTNGVVHANLFGIKDWVTPYKIAVLVLLNEMGRTGEGAVSLVERRKLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDLEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMDREDGERQMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQAALLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAEGKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRADSYVLLEHSVKKAVHFGLPRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESLSAGVQQNNTESFAVALCHLAELHAEQGCFAAAGEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKFHLADSLVTGITALNGIEGVYRKAVVLQAQNQMTEAHKLLQKLLTYCQKLKNTEMVISVLLSVAELYWRSSSPTIAMPVLLEALALSKEYRLQYLASETVLNLAYAQLILGIPEQALTLLHMAIEPILADGAILDKGRAMFLVSKCQVASAASYDPVKKAEALEAAIQNLTEAKNYFAKVDCRERIRDVSYFQARLYHALGKTQERNHCAMVFRQLHQELPSHGVPLINHL", "length": 727 }, "evidence": [ { "id": "E1BK11", "url": "https://omabrowser.org/oma/group/E1BK11/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RNP8-1", "protein_name": "Anaphase-promoting complex subunit 5", "gene_name": "ANAPC5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMGRTGEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELASREEGERKMEKEELDVSIREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNGQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAIVLQAQNQMSEAHKLLQKLLIHCQKIRNAEMVISVLLSVAELSWRSSSPTIALPVLLQALALSKEYRLQHLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAVLDKGRAMFLVAKCQVASAASYEPLKKVEALEAAIENLSEAKNYFAKVDCKEQIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQELPFHGVPLINLL", "length": 755 }, "evidence": [ { "id": "E1BK11", "url": "https://omabrowser.org/oma/group/E1BK11/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5ZKK3-1", "protein_name": "Anaphase-promoting complex subunit 5", "gene_name": "ANAPC5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKMALLVLLSELGRAGSQLDQLERRRLNRLLLPLLQGPDMPLSRLRKAIEECCPNLAGSVHIRLKLIAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVIGLFLRHMILAYNKLSFSQVYKLYTALQQYFLNDEKKCGIDENDMELTNTEELDGKMEKEELDVPLREEEISCSGPLSQKQAEYFLSQQASLLKNDETKALSPVSLQKELNNLLKFNPDFAEAHYLSYLNSLRVHDVFSSTHSLLHYFDRLILTGAESKSNGDEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLHISEQKIFDSCVLLEHSVNKSLHFGLPYLASLGIQSLVQQRAFAGKAANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQTLLSMNSLEAVNVGVQQNNTEAFAVVLCHLAELHAEQGYFAAASEILKHLKERFPPNSQHAQLWMLFDQKIQFERAMNDGRYHIADSLVAGITALNSIEGMYRKAIVLKAQNQMLEAHKLLQKLLIHCQEIKNTEIVISVLLSVAELYWRSSCHTIALPVLLQALAFSREYSLQYLASETVLNLAFSQLILGVPEQVLNILHMAIEPGLAHGAVLDKGCAMFLVAKCQVASTASYSQQKKAEALESAILNLNEAKTYLAKVDCKEQLRDVLYFQARLFHTLGKTQERNKCAMLFRQLHQELPAHGVPLINAFK", "length": 756 }, "evidence": [ { "id": "E1BK11", "url": "https://omabrowser.org/oma/group/E1BK11/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8BTZ4-1", "protein_name": "Anaphase-promoting complex subunit 5", "gene_name": "Anapc5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMTNGVVHANLFGIKDWVTPYKIAVLVLLNEMGRTGEGAVSLVERRKLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMDREDGEKQMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQAALLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAEGKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRADSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESLNAGVQQNNTESFAVALCHLAELHAEQGCFAAAGEVLKHLKDRFPPNSQHAQLWMLCDQKIQFDRAMNDGKFHLADSLVTGITALNGIEGVYRKAVVLQAQNQMTEAHKLLQKLLTYCQKLKNTEMVISVLLSVAELYWRSSSPTIAMPVLLEALALSKEYRLQYLASETVLNLAYAQLILGIPEQALTLLHMAIEPILADGAVLDKGRAMFLVSKCQVASAASYDPVKKAEALEAAIQNLSEAKNYFAQVDCRERIRDVAYFQARLYHALGKTQERNHCAMIFRQLHQELPAHGVPLINHL", "length": 740 }, "evidence": [ { "id": "E1BK11", "url": "https://omabrowser.org/oma/group/E1BK11/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UJX4-1", "protein_name": "Anaphase-promoting complex subunit 5", "gene_name": "ANAPC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL", "length": 755 }, "evidence": [ { "id": "E1BK11", "url": "https://omabrowser.org/oma/group/E1BK11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VZL2-1", "protein_name": "Anaphase-promoting complex subunit 5", "gene_name": "ida", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MILCLHFAGKSKIGFRGPKLTMNLFEELDTLDPSFKLEPPRIETPTAHKITVLILLKQYVINKKNCLDTGISMRTQRRRMFYMLVFKLIQEQDKSYNELHSLLTTGKYKLDTLMLESFEKAMSEFCAGSIEALFDFSEIQNIDEILNENYGISQFSMVGVYVRRVGVVLERLSFPEMMDMYKNVCSYYERGVRAAASGSRMAVAGGILHREETPPPNPITEKPEDPKPKKKVEAVARIAQERNPLSKWAPKQAKFFINKQSELLENNERKALPPLELQKKVQEIIHDLPLTTTPYFLGYMNQLRVRDYYNALSALHRALDRSPVRLMSQEKGYQYFCVNLAVLHATFGHRDEALAALRESIMLAQEHGDKRSLNLANTWYCLLRDELPLSAVQKSVQDANEVDGSLLQNYTLALHFAVKLGTVAGYQPLRLFDLLQHSDNLTNRNNFADHASEALALRSAVWSAYGRHELAALYSQVLLTGRDRFGSGSAGLGSALASFALWLQLQGEPQLSKVLLHHAKQRFPRLPSAEGWMISQCHVVIQAGIYQCRWHDALKACDQLYLIDPSDSLFQRASIYVAKREFFNARRLLDKLAVQDNIPFLLRMRVQVLLGYCGMANGRFSSETTMLLLRVSEEMSEAQMDYELALVDLLLALQLLLLGMPQKAYQAIKRCMHDIHINGGLYERAKTDFVFVRCLLAVNQNDAEKRKAQLLKSQVILQRAAQSFKKLSAHAKVLDVYVFLAQRFNEFGDRNLRNKYAGEFRRYFTDHPIPREYLGSP", "length": 777 }, "evidence": [ { "id": "E1BK11", "url": "https://omabrowser.org/oma/group/E1BK11/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11" } ], "pmid": "" }, { "name": "positive regulation of mitotic metaphase/anaphase transition", "id": "GO:0045842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045842", "evidence": [ { "database": "UniProtKB", "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11" } ], "pmid": "" }, { "name": "protein branched polyubiquitination", "id": "GO:0141198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141198", "evidence": [ { "database": "UniProtKB", "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "E1BK11", "url": "https://www.uniprot.org/uniprotkb/E1BK11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BK11-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 755, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BK11-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BK11" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BK11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK11" }, { "id": "PF12862", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12862" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anaphase-promoting complex subunit 5", "eco_id": "ECO_0000259", "start_pos": 254, "end_pos": 353, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BK11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK11" }, { "id": "PF21371", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21371" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anaphase-promoting complex subunit 5 N-terminal", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 169, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 461, "end_pos": 463 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK12-1", "uniprot_ac": "E1BK12", "uniprot_id": "E1BK12_BOVIN", "mass": { "chemical_mass": 29843.0, "monoisotopic_mass": 29843.0 }, "refseq": {}, "gene_names": [ { "name": "PLSCR1", "type": "recommended", "evidence": [ { "id": "E1BK12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK12" } ] } ], "protein_names": [ { "name": "Phospholipid scramblase", "type": "recommended", "evidence": [ { "id": "E1BK12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK12/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "E1BK12", "url": "https://www.uniprot.org/uniprotkb/E1BK12#function" }, { "database": "UniProtKB", "id": "RU363116", "url": "https://www.uniprot.org/uniprotkb/RU363116#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK12", "url": "https://www.uniprot.org/uniprotkb/E1BK12" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PLSCR1", "url": "https://www.uniprot.org/uniprotkb/E1BK12", "locus": { "chromosome": "1", "start_pos": 122092789, "end_pos": 122041887, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000031306", "url": "https://www.ensembl.org/id/ENSBTAG00000031306" } ] } } ], "crossref": [ { "id": "E1BK12", "url": "https://alphafold.ebi.ac.uk/entry/E1BK12", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000031306", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000031306", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR005552", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005552", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SCCWRNC", "url": "https://omabrowser.org/oma/group/SCCWRNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BK12", "url": "https://www.orthodb.org/?gene=E1BK12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23248", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23248", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23248:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23248:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03803", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03803", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BK12", "url": "https://www.uniprot.org/uniprotkb/E1BK12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK12-1", "url": "https://www.uniprot.org/uniprotkb/E1BK12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFCNIQPRTHWMQTPGSTANCPPGLEYLTQINHLFVCQRFDLLEVFSPFETNKTYDVMNNQGQRLYFAEEKSNCFIRHLCGPSRPFTMTIYDNVGCDVITLHKALRWSCCWSNCCLQKLKVEAPPGEIIGYVYQYYHPFLPMFKITNENKENLMKIRGPCVVSSCLKDLNFNLLSLDEEMIIGKISNQWIGFMRELFTNTNKFGIQFPFDLDVRIKALLLGASFLIRTTCILNSGHKSQPEKSYQTLLALSFASPQQN", "length": 259, "header": "tr|E1BK12-1|E1BK12_BOVIN Isoform 1 of Phospholipid scramblase OS=Bos taurus OX=9913 GN=PLSCR1 PE=3 SV=3 CANONICAL=E1BK12-1" }, "isoforms": [ { "isoform_ac": "E1BK12-1", "url": "https://www.uniprot.org/uniprotkb/E1BK12/entry#E1BK12-1", "sequence": { "sequence": "MAFCNIQPRTHWMQTPGSTANCPPGLEYLTQINHLFVCQRFDLLEVFSPFETNKTYDVMNNQGQRLYFAEEKSNCFIRHLCGPSRPFTMTIYDNVGCDVITLHKALRWSCCWSNCCLQKLKVEAPPGEIIGYVYQYYHPFLPMFKITNENKENLMKIRGPCVVSSCLKDLNFNLLSLDEEMIIGKISNQWIGFMRELFTNTNKFGIQFPFDLDVRIKALLLGASFLIRTTCILNSGHKSQPEKSYQTLLALSFASPQQN", "length": 259, "header": "tr|E1BK12-1|E1BK12_BOVIN Isoform 1 of Phospholipid scramblase OS=Bos taurus OX=9913 GN=PLSCR1 PE=3 SV=3 CANONICAL=E1BK12-1" }, "locus": { "chromosome": "1", "start_pos": 122092748, "end_pos": 122054726, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044362.4", "url": "https://www.ensembl.org/id/ENSBTAT00000044362.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041866.4", "url": "https://www.ensembl.org/id/ENSBTAP00000041866.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BK12", "url": "https://www.uniprot.org/uniprotkb/E1BK12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "plasma membrane phospholipid scrambling", "id": "GO:0017121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017121", "evidence": [ { "database": "UniProtKB", "id": "E1BK12", "url": "https://www.uniprot.org/uniprotkb/E1BK12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phospholipid scramblase activity", "id": "GO:0017128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017128", "evidence": [ { "database": "UniProtKB", "id": "E1BK12", "url": "https://www.uniprot.org/uniprotkb/E1BK12" } ], "pmid": "" } 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{ "id": "E1BK36-1", "url": "https://www.uniprot.org/uniprotkb/E1BK36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPEAPAGQAPAAASKLSEAVGAALQDPRRQRRLVLVIVCVALFLDNMLYMVIVPIVPYYVHAASEKPTPTPSPTPPTPTNASAVTVNTSEPPTAAMPAKSIVKPQHPRDNEDVKIGVLFASKAILQLLVNPLSGTFIDRMSYDLPLLLGLGVLFASTVMFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGLALAFISFGSLVAPPFGGFLHEFAGKSAPFLVLAAVSLFDALLLLVVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMERTMAASEWEAGIAWLPAFVPHVLGVYLTVRLAARYPHLQWLYGAFGLAVIGASSCLVPACRSFAPLVISLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYCVAYALGPIVAGHIVHSLGFAQLSLGMGLANLLYAPVLLLLRNVGLLKRSRSERDVLLDEPPQGLYDAVRLRERPMSDRDGAPRSPPGPFDACEEDDYDYYTRS", "length": 524, "header": "tr|E1BK36-1|E1BK36_BOVIN Isoform 1 of Solute carrier family 18 member 3 OS=Bos taurus OX=9913 GN=SLC18A3 PE=3 SV=2 CANONICAL=E1BK36-1" }, "isoforms": [ { "isoform_ac": "E1BK36-1", "url": "https://www.uniprot.org/uniprotkb/E1BK36/entry#E1BK36-1", "sequence": { "sequence": "MEPEAPAGQAPAAASKLSEAVGAALQDPRRQRRLVLVIVCVALFLDNMLYMVIVPIVPYYVHAASEKPTPTPSPTPPTPTNASAVTVNTSEPPTAAMPAKSIVKPQHPRDNEDVKIGVLFASKAILQLLVNPLSGTFIDRMSYDLPLLLGLGVLFASTVMFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGLALAFISFGSLVAPPFGGFLHEFAGKSAPFLVLAAVSLFDALLLLVVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMERTMAASEWEAGIAWLPAFVPHVLGVYLTVRLAARYPHLQWLYGAFGLAVIGASSCLVPACRSFAPLVISLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYCVAYALGPIVAGHIVHSLGFAQLSLGMGLANLLYAPVLLLLRNVGLLKRSRSERDVLLDEPPQGLYDAVRLRERPMSDRDGAPRSPPGPFDACEEDDYDYYTRS", "length": 524, "header": "tr|E1BK36-1|E1BK36_BOVIN Isoform 1 of Solute carrier family 18 member 3 OS=Bos taurus OX=9913 GN=SLC18A3 PE=3 SV=2 CANONICAL=E1BK36-1" }, "locus": { "chromosome": "28", "start_pos": 43742707, "end_pos": 43741136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019955.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019955.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019955.5", "url": "https://www.ensembl.org/id/ENSBTAP00000019955.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 69, "start_aa": "Thr", "end_pos": 69, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr69", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 71, "start_aa": "Thr", "end_pos": 71, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 75, "start_aa": "Thr", "end_pos": 75, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr75", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 78, "start_aa": "Thr", "end_pos": 78, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr78", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 94, "start_aa": "Thr", "end_pos": 94, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr94", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:785833", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785833", "resource": "KEGG Pathway" }, { "id": "R-BTA-264642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-264642", "resource": "Reactome", "description": "Acetylcholine Neurotransmitter Release Cycle" }, { "id": "R-BTA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-BTA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZKD5-1", "protein_name": "Solute carrier family 18 member 3", "gene_name": "SLC18A3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAVAPAGQAPAAASKLSEVVGAALQDPRRQRRLVLVIVCVALFLDNMLYMVIVPIVPYYISAANENPTPTSKVNAPILLPTTPANASANMANTSESSTAATPAGSTVKPHYPEDSEDVKIGALFASKAILQLLVNPLSGTFIDRMSYDLPLLMGLGVLFASTVMFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGLALAFISFGSLVAPPFGGFLHKFAGKPAPFLVLATVSLLDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASELETGMAWLPAFVPHLLGVYLTVRLAARYPHLQWLYGAFGLAVIGASSCLVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFTQLSLGMGLANLLYAPVLLLLRNVGLLKRSRSERDVLLDEPPQGLYDAVRLRERPVSDRDGAPGSPPGPFDECEDDYDYYARS", "length": 528 }, "evidence": [ { "id": "E1BK36", "url": "https://omabrowser.org/oma/group/E1BK36/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LPH6-1", "protein_name": "Solute carrier family 18 member 3", "gene_name": "Slc18a3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPTAPTSQARAAATKLSEAVGAALQEPQRQRRLVLVIVCVALLLDNMLYMVLVPIVPDYIAHMRGGSESPTLASEVWEPTLPPPTLANASAYLTNTSASPTVAGSGRSILRPRYPTESEDVKIGLLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVMFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLIVRLAARYPHLQWLYGALGLAVIGVSSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRSERDVLLDEPPQGLYDAVRLRERSVQGTDGDGGEPCSPPGPFDGCEDDYSYYTRS", "length": 534 }, "evidence": [ { "id": "E1BK36", "url": "https://omabrowser.org/oma/group/E1BK36/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O17444-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "VAChT", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASFQIPVINLEVREVKDIVWEKIQEPVNQRRLILVIVSIALLLDNMLYMVIVPIIPDYLREIGSFDDGPTPPPLRDNITGKIIPVHHDHHGQDSATGILFASKAIVQLMVNPFSGGLIDKIGYDLPMMIGLTIMFFSTAVFACGSSYSVLFFARSLQGAGSAFADTAGLAMIADRFTEENERSQALGIALAFISFGCLVAPPFGGALYQFAGKEVPFLILALVCLLDGLMLLLVMKPVKEAMKQSKDVQDQVIPIWRLLMDPYIAVCAGALTMSNVALAFLEPTISLWMEDNMTTDNWKIGMVWLPAFFPHVLGVVITVKMARKYPQHQWLMAAGGLALEGFSCFIIPFCSGYKMLMLPICVICFGIALIDTALLPTLGYLVDVRYVSVYGSIYAIADISYSIAYAVGPIIAGGVVEAIGFTALNFLIAFSNLAYVPVLRKLRNIYDFKPFENEANILMQDPPNKEYQTYVMHDQKPVEGGVKNHLEYGQQYQQEQETNLDDQQYEYQQQQQGYQQGYQQDQGYQPGYQEQGGSYAPQGQPRVANPFQQQQQQQQQQQQQVQSRGPAAPANPFRQGF", "length": 578 }, "evidence": [ { "id": "E1BK36", "url": "https://omabrowser.org/oma/group/E1BK36/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYIAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRSERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS", "length": 532 }, "evidence": [ { "id": "E1BK36", "url": "https://omabrowser.org/oma/group/E1BK36/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "E1BK36", "url": "https://www.uniprot.org/uniprotkb/E1BK36" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "E1BK36", "url": "https://www.uniprot.org/uniprotkb/E1BK36" } ], "pmid": "" }, { "name": "AP-2 adaptor complex", "id": "GO:0030122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030122", "evidence": [ { "database": "UniProtKB", "id": "E1BK36", "url": "https://www.uniprot.org/uniprotkb/E1BK36" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "E1BK36", "url": "https://www.uniprot.org/uniprotkb/E1BK36" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "E1BK36", "url": "https://www.uniprot.org/uniprotkb/E1BK36" } ], "pmid": "" }, { "name": "serotonin uptake", "id": "GO:0051610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051610", "evidence": [ { "database": "UniProtKB", "id": "E1BK36", "url": "https://www.uniprot.org/uniprotkb/E1BK36" } ], "pmid": "" }, { "name": "acetylcholine uptake", "id": "GO:0051630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051630", "evidence": [ { "database": "UniProtKB", "id": "E1BK36", "url": "https://www.uniprot.org/uniprotkb/E1BK36" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "acetylcholine transmembrane transporter activity", "id": "GO:0005277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005277", "evidence": [ { "database": "UniProtKB", "id": "E1BK36", "url": "https://www.uniprot.org/uniprotkb/E1BK36" } ], "pmid": "" }, { "name": "monoamine:proton antiporter activity", "id": "GO:0015311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015311", "evidence": [ { "database": "UniProtKB", "id": "E1BK36", "url": "https://www.uniprot.org/uniprotkb/E1BK36" } ], "pmid": "" }, { "name": "acetylcholine:proton antiporter activity", "id": "GO:0005278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005278", "evidence": [ { "database": "UniProtKB", "id": "E1BK36", "url": "https://www.uniprot.org/uniprotkb/E1BK36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "72891", "name": "", "equation": "acetylcholine(out) + 2 H(+)(in) = acetylcholine(in) + 2 H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72891", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72891" } ] }, { "id": "73743", "name": "", "equation": "serotonin(in) + 2 H(+)(out) = serotonin(out) + 2 H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73743", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73743" } ] }, { "id": "73819", "name": "", "equation": "choline(in) + 2 H(+)(out) = choline(out) + 2 H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73819", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73819" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BK36-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 524, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BK38-1", "uniprot_ac": "E1BK38", "uniprot_id": "E1BK38_BOVIN", "mass": { "chemical_mass": 557201.0, "monoisotopic_mass": 557201.0 }, "refseq": {}, "gene_names": [ { "name": "ABCA13", "type": "recommended", "evidence": [ { "id": "E1BK38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ] } ], "protein_names": [ { "name": "ATP binding cassette subfamily A member 13", "type": "synonym", "evidence": [ { "id": "E1BK38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK38/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ABCA13", "url": "https://www.uniprot.org/uniprotkb/E1BK38", "locus": { "chromosome": "4", "start_pos": 7204759, "end_pos": 7598351, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003531", "url": "https://www.ensembl.org/id/ENSBTAG00000003531" } ] } } ], "crossref": [ { "id": "ENSBTAG00000003531", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003531", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229:SF113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229:SF113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26955", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26955", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK38-1", "url": "https://www.uniprot.org/uniprotkb/E1BK38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM08", "url": "https://www.uniprot.org/uniprotkb/E1BM08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM08-1", "url": "https://www.uniprot.org/uniprotkb/E1BM08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "NYDVLSLAEFFWPCILFMILTVLRFQEPPRHRDNCYLQPRDLPSRGVFPFVQGLLCNTGSRCRNTSYEGAMEQRFRSPRFPAAAAPHQKVDNLAFLKEIQDLAQEVYEVMDKARNLQKLWAERSKTPGNCCGPAPPRLPHGVLFHQMDLNKTEEVIEKLESLHQQPHLWDFLLLLPRLYTNTFHVADGVLAGGHLLHAVLTSLSALEDLDWLPLNHTFFRVSEMVLKAAVSTLASLQESGAVATESGYSLSVKELMWDPQKVQADLKSQFGFDDLHAERVLNYSADLDEIPTDGSLEQMLCSALSGSSEDEDDGEGRPADCDPQWSAAKDYLVQAVSRLHLYRQVFDQQWKGSLFQQVLAGIGRGLEALRTQSGEGSQPWKVVRALQAAFLLLNDSMAADGPEGSHTPTRILLYMQRLQRVLRKLPPGPALMRLLQLDGALRNAGAQDLHLVREILICLEASANNSRSHGPGQSKLEKDVLFKELKQNTRENQVLFPFAPAFLANHLLQAAITGHTSMPVSIPEDAPDWQDLGAQLQEASLPCTRLLRLLRADVSAADCADQLFSTVMFHTLEKAQSFLEHTHFWKAFMGFIRKTCEVARYVNKQEGIQNSSLGFSEESPCYKENMDWKSISGNYFAFLNNLFRTPTASMSRVLNYTKELLVMEKKLQTHKDEQINFLLSFMEFLEKLLPNPFNLSSILKFYNLPSVPEMTLNTSHLWLNHSASLGRDIPGMDTQKLLEVSKEMIEKIETHESFWIRKESINILRFVELMLLGMNPKFLAFWMHGASKEKRAELGLLPALANLSDSENEMIHRKSFNFSQLFHSDWPQSPAMKMDFVHVIEVIINSLYEFGFLSQEQVSETVDTLYAMRNASSLFLALSEPQKQDIEKILTCVYLHVFQDKDSALLLQIYSSFHQYMYKFMSIQSRESLLFLLMQISKHILDILKQFNFQNINKAFSFLYETTGVLGRISEVPYCQQLLSIFNFLELQAQSLVSTEGPAMEVIHATLRGLKHLFMVDDGFRNSVFQYVSQLFNGSAEALLGDECFVLDNKSISSANYSPAEGSPFILPWAQILSNFPADGSEFHEFTALHCTTLWLHTWTEVCGHIAQIFQLDTNVFTPLRVGLSQLLDELESDEKIPTSCQEVIPNRHPARLILHLFKNVTQTDGFRDWNDFLNLRDLWVALGDGFVRVKLLNLDQIEKSLFTMETTLSQLKSLDTNTSREFLYSLLNIFIELSNTSASIDRSVHLMNHFLLRNLTNYEVKFASVITDLRDTVLFLKNMSHNQDLLSCADIFQNVTEFILEDGLLYENSSQRAFHILAMLNSTFSSVDIVSRLKGCATWVSAINHLCAVYNSSFSQGHLHGVLQSLREVKDKLNSTLKLVTGMLTIMMEPCSLNRSHINCVNVYLKNVTDFLNILLTAVFGKEKVPHFEILLTLLNDSTNQVRMIINNVSRDFDFVPQSNWTHFTELILKPIEMSDEMPLQFQNIWLQLVALGKEIQNLVKDISPNNLENNTSYKAEKNLNIIATSPKEKDIHSLGNSFYQLASYLTFNLSHDLQSSPKIISQEVMKAVGLSIQLMKDLFNSLKPSAYHNIPQEPGDLQILKKMTSVLHTVKKTDIYLLVDQLEHISESMMDFFKNISRLGASNLGIGFFVDLMEKFVNSSHSWSINHLLRLSRLFPKKGADSLVDVYYMLPHAMRLLRGMGNKNITEALRDVYNFTLLHGIHLSDVTKEDFTAAIKTLMDTIESVSAQPGILSETLACLPVFWCWNHTTSGFQQNPRSDACNAHKLTSSFYSKVASILDHLHLSPHGDDSQCLNESSQMEITRKVACVIHELMDWSSILLELCEVFHIKTPLVKSVQEFWHKVLPFVQLSGNQSSGGISELCPGHLIKQVALPIIEKFKNFNFTKVTSDENLLEKLVSLNKVLNVDEGADTSVRYNISFRLKRITDFLSRKENLVNSTNSLVSPFMTLLNANLTGSSLEALSCFIKKSKAAYNLEKQWLEFEQIMKDITHNFSIRPLYSKIDNMIQRTSSVALQNITLPLAHFLESLDLSSLKTLEIIEDFLLVIKNWFHKFANEDYSKMIQTLFLLLANKSSTDDIALVTKDIATFLGYLKNVSREGNFDVALLTRLLSQEQLTNFSVVQLLFESFLINSVNDLAERSQGAALNLSDADLQIMNLINLVLNHTQSENGERVVFPPRSRMGFMEQLLKTFFFLLKENSGKKIFLLLKDIHKDLFAEMSFVPKDKILENLKLNHFLTSMKEDRLVSAFSTLKETVYHLIKNSFTLDDGELYFDNHQGLQLLGDLFHTLLRETSMKNETENDLEFLMVLNQLLSHMNSSEDLFKLNQDLRSALHLVRETSIVIAHFMDTLLSSPVKDFRVLYPSLQEVILANLTDLLSFVNNSFPLRNRATLEITRHLLGVISGAGGGNCTPDPLLEMSDTLTMLADDGVEMKGLATSVTSTVKFLKLAKKIARKVATMFQTHLISIANDTMKFFDTLYFLLLQSVRNVVNEMITLKKADHLIFENIDDLLMLFLDLAFGMIGVKPNISQDSDILNMSSGIFTYMNQSKHLYDIREEIADFLTSVKINLGDVERLLAAFKNGAQIFSVDSVNLWEEILDCLVLINNITSHIDFLYSNPTSTHNFPRDTKWEITHEVILFLREILSQNRTELGSYLRTVINLISVTLWNDTGKDHRGVLNLLLTLAPHPDDLLKLIRTAAEASCEASLFNTSWIQNVTEQQLQEAIQTLLRKIALVKKELLLNSSQWTHSMSTLLQPFFEIFIHATTGTHEKTQKELVDIPNILKPLSHFEKYRKALIALVEYWQRVSLIDQRAEENCILMASLCVSSAENHSLTKDVLCAALHCEQSVARLLLLAALRAVVLGHDHYQELEKIWTSPHQLSCEGLHRNLSRALESFRSSLEDASEQDCESLIFCHFRLAQSLEKTLLLSGNPIMTFLSNFTVAEDVKVKDLMQNISKLTEELRSSLHISDGTINSILEANISHSKVLPSVLTVALSGSCNRDILQLLLQFPEDGKSESAARELCGLPRAQVFSMIVVLARNLDLRNFVYKTLLPAEASSLLRALLDVVSSLSHLLPRAGRVLERLPAFLHEFKITALLDAPDFQQVGSNQARSSAIGSFQSLMKMVCKDQASFFSSSDTFLNLPRVHELLGDDKEKFNIPEDSTPFCLKLYQEILQSPNGALVWSFLKPVLHGKILYTPNTPEINKVIQKVNHTFDFVGKLKTLSETLLSASSIFQSSGNGQMLHQLQEALKNKFIRSFIKSQLHIDVGKLTEKLQIFGGKLDAMLNHTGAGRLRSLGRVLVDLASCVRLNRFRGLASAAALEATAQALLRKNTLLASIIFNSSLVGKNLSSESLQLPPQVTYSIRTSILYSMRTDLVKNPFWKFHPQSLPADGFKYNYIFVPLQDMIERAIISVQTGQEALDPATQAQAIPYPCHTSDLFLNNVGFFFPLIMMLTWMVSVASMVRKLVYEREIQLEEYMRMMGVHPAVHFLAWFLENVAVLTVSSAALALVLKVSGIFTYSSAWIVFLFLLDFAVSVVTLSYLLSALFSRASMAALCSSLLYTASFLPYIVLLVLHDQMGATLQTLLCLLSTTAFGQGVFFITFLEGQEAGIQWDNMYQSPEVAGMTFGWVCWMILFDSGLYFLCGWYLNSLIPGTFGLRKPWYFPFTASYWKDVCGLVMKRQSPASSKLFSSSENLDGQGSSLQNGKGELEGGSPGVVLLSVTKEHDRHKAGVWDLTLTFHRDQITALLGTNGAGKTTVISLLTGLYPPTSGTITVNGRSLQKDPSVVRAELGVCLQWDILFDRLTVLEHLMLFASLKALRGTRQELREQVHRTLQDVGLTPHQHQQARVLSGGTRRKLSIGIAFLGASGTVVLDEPTSGVDPCSRRGIWDILLKYRQGRTIIFTTHHLDEAEALSDHVAVLQRGRLRCSGPPASLTQAHAQGFRLTLSRQPSVPEADDLKDTACATSLIQTYLPQASLQSSSQGELSYVIPEGADRACFRGLFQALDQNLHQLCLTGYGLSDTTLEEVFLHLLQDSKKQPDTALSLESAPPEPGPGHHLPHLPLLADRTPAGTPLVRGGPLLLAQTTALLRKRLLHARRAWKGTISDLLLPVLFVALAMALFMVRPLAINYPPLKLALGHYDKAETYFFSSENDGLELTRVLLRKFGDQDPPCADLYPDLWRRIGWQDLLKCPNASTRAPYLTNRLGHRLLNLSGLPLEEYLLAPMEKPRLGGWSFGVQIPNQVQDTNSNMSKPQNLAKVWYNQKGFHSLPSYLNHLNNLILWRRLPPTADWRQYGITLYSHPYGGALLNEDKILESIRQCGVALCIVLGFSILSASIGSSVVQDRVTGAKRLQHVSGLGYRTYWLTHFLFDMLLYLVSVCLCVSVIMAFQLTAFTFRENLAATALLLVLFGYATLPWMYLVSRIFSSSDVAFISYISLNFIFGLCTMLMTVMPRLLAIVSKAQNLQNIYDVLKWVFTIFPQFCLGQGLIELCYNQIRYDLTHNFGVDSYVSPFEMNFLGWIFVQLAVQGSVLLLLRVLLHRDLWLQPRGHSAIQGTVTSSKDIDVEKEQVRVLKGRTSGDTLVLYNLSKSYRGFFKSTTAVQDISLGVRRGECFGLLGVNGAGKTTTFKMLTGDLPPSSGHAVVRTPTGEDVNLSLAGAAGIRIGYCPQQDALDELLTGWEHLHYYCCLHGIPKQSIPKVAGDLVRRLHLEAHVDKPVATYSGGTKRKLSTALALLGKPDLLLLDEPSSGMDPCSKRHLWEALRKEAEEGCAVVLSSHSMEECEAVCTRLAIMVHGSFRCLGSPQHIKNRFGDGYTVKIWLHKEVDQHSAVSDCLKLYFPGIQFKGQRLNLLEYHMPKRWVCLANLFRVLEDNKSFLNIRHYSINQTTLEQIFVNFATEQWQTPSPSELSAKCDHSRHLPV", "length": 4945, "header": "tr|E1BK38-1|E1BK38_BOVIN Isoform 1 of ATP binding cassette subfamily A member 13 OS=Bos taurus OX=9913 GN=ABCA13 PE=4 SV=4 CANONICAL=E1BK38-1" }, "isoforms": [ { "isoform_ac": "E1BK38-1", "url": "https://www.uniprot.org/uniprotkb/E1BK38/entry#E1BK38-1", "sequence": { "sequence": "NYDVLSLAEFFWPCILFMILTVLRFQEPPRHRDNCYLQPRDLPSRGVFPFVQGLLCNTGSRCRNTSYEGAMEQRFRSPRFPAAAAPHQKVDNLAFLKEIQDLAQEVYEVMDKARNLQKLWAERSKTPGNCCGPAPPRLPHGVLFHQMDLNKTEEVIEKLESLHQQPHLWDFLLLLPRLYTNTFHVADGVLAGGHLLHAVLTSLSALEDLDWLPLNHTFFRVSEMVLKAAVSTLASLQESGAVATESGYSLSVKELMWDPQKVQADLKSQFGFDDLHAERVLNYSADLDEIPTDGSLEQMLCSALSGSSEDEDDGEGRPADCDPQWSAAKDYLVQAVSRLHLYRQVFDQQWKGSLFQQVLAGIGRGLEALRTQSGEGSQPWKVVRALQAAFLLLNDSMAADGPEGSHTPTRILLYMQRLQRVLRKLPPGPALMRLLQLDGALRNAGAQDLHLVREILICLEASANNSRSHGPGQSKLEKDVLFKELKQNTRENQVLFPFAPAFLANHLLQAAITGHTSMPVSIPEDAPDWQDLGAQLQEASLPCTRLLRLLRADVSAADCADQLFSTVMFHTLEKAQSFLEHTHFWKAFMGFIRKTCEVARYVNKQEGIQNSSLGFSEESPCYKENMDWKSISGNYFAFLNNLFRTPTASMSRVLNYTKELLVMEKKLQTHKDEQINFLLSFMEFLEKLLPNPFNLSSILKFYNLPSVPEMTLNTSHLWLNHSASLGRDIPGMDTQKLLEVSKEMIEKIETHESFWIRKESINILRFVELMLLGMNPKFLAFWMHGASKEKRAELGLLPALANLSDSENEMIHRKSFNFSQLFHSDWPQSPAMKMDFVHVIEVIINSLYEFGFLSQEQVSETVDTLYAMRNASSLFLALSEPQKQDIEKILTCVYLHVFQDKDSALLLQIYSSFHQYMYKFMSIQSRESLLFLLMQISKHILDILKQFNFQNINKAFSFLYETTGVLGRISEVPYCQQLLSIFNFLELQAQSLVSTEGPAMEVIHATLRGLKHLFMVDDGFRNSVFQYVSQLFNGSAEALLGDECFVLDNKSISSANYSPAEGSPFILPWAQILSNFPADGSEFHEFTALHCTTLWLHTWTEVCGHIAQIFQLDTNVFTPLRVGLSQLLDELESDEKIPTSCQEVIPNRHPARLILHLFKNVTQTDGFRDWNDFLNLRDLWVALGDGFVRVKLLNLDQIEKSLFTMETTLSQLKSLDTNTSREFLYSLLNIFIELSNTSASIDRSVHLMNHFLLRNLTNYEVKFASVITDLRDTVLFLKNMSHNQDLLSCADIFQNVTEFILEDGLLYENSSQRAFHILAMLNSTFSSVDIVSRLKGCATWVSAINHLCAVYNSSFSQGHLHGVLQSLREVKDKLNSTLKLVTGMLTIMMEPCSLNRSHINCVNVYLKNVTDFLNILLTAVFGKEKVPHFEILLTLLNDSTNQVRMIINNVSRDFDFVPQSNWTHFTELILKPIEMSDEMPLQFQNIWLQLVALGKEIQNLVKDISPNNLENNTSYKAEKNLNIIATSPKEKDIHSLGNSFYQLASYLTFNLSHDLQSSPKIISQEVMKAVGLSIQLMKDLFNSLKPSAYHNIPQEPGDLQILKKMTSVLHTVKKTDIYLLVDQLEHISESMMDFFKNISRLGASNLGIGFFVDLMEKFVNSSHSWSINHLLRLSRLFPKKGADSLVDVYYMLPHAMRLLRGMGNKNITEALRDVYNFTLLHGIHLSDVTKEDFTAAIKTLMDTIESVSAQPGILSETLACLPVFWCWNHTTSGFQQNPRSDACNAHKLTSSFYSKVASILDHLHLSPHGDDSQCLNESSQMEITRKVACVIHELMDWSSILLELCEVFHIKTPLVKSVQEFWHKVLPFVQLSGNQSSGGISELCPGHLIKQVALPIIEKFKNFNFTKVTSDENLLEKLVSLNKVLNVDEGADTSVRYNISFRLKRITDFLSRKENLVNSTNSLVSPFMTLLNANLTGSSLEALSCFIKKSKAAYNLEKQWLEFEQIMKDITHNFSIRPLYSKIDNMIQRTSSVALQNITLPLAHFLESLDLSSLKTLEIIEDFLLVIKNWFHKFANEDYSKMIQTLFLLLANKSSTDDIALVTKDIATFLGYLKNVSREGNFDVALLTRLLSQEQLTNFSVVQLLFESFLINSVNDLAERSQGAALNLSDADLQIMNLINLVLNHTQSENGERVVFPPRSRMGFMEQLLKTFFFLLKENSGKKIFLLLKDIHKDLFAEMSFVPKDKILENLKLNHFLTSMKEDRLVSAFSTLKETVYHLIKNSFTLDDGELYFDNHQGLQLLGDLFHTLLRETSMKNETENDLEFLMVLNQLLSHMNSSEDLFKLNQDLRSALHLVRETSIVIAHFMDTLLSSPVKDFRVLYPSLQEVILANLTDLLSFVNNSFPLRNRATLEITRHLLGVISGAGGGNCTPDPLLEMSDTLTMLADDGVEMKGLATSVTSTVKFLKLAKKIARKVATMFQTHLISIANDTMKFFDTLYFLLLQSVRNVVNEMITLKKADHLIFENIDDLLMLFLDLAFGMIGVKPNISQDSDILNMSSGIFTYMNQSKHLYDIREEIADFLTSVKINLGDVERLLAAFKNGAQIFSVDSVNLWEEILDCLVLINNITSHIDFLYSNPTSTHNFPRDTKWEITHEVILFLREILSQNRTELGSYLRTVINLISVTLWNDTGKDHRGVLNLLLTLAPHPDDLLKLIRTAAEASCEASLFNTSWIQNVTEQQLQEAIQTLLRKIALVKKELLLNSSQWTHSMSTLLQPFFEIFIHATTGTHEKTQKELVDIPNILKPLSHFEKYRKALIALVEYWQRVSLIDQRAEENCILMASLCVSSAENHSLTKDVLCAALHCEQSVARLLLLAALRAVVLGHDHYQELEKIWTSPHQLSCEGLHRNLSRALESFRSSLEDASEQDCESLIFCHFRLAQSLEKTLLLSGNPIMTFLSNFTVAEDVKVKDLMQNISKLTEELRSSLHISDGTINSILEANISHSKVLPSVLTVALSGSCNRDILQLLLQFPEDGKSESAARELCGLPRAQVFSMIVVLARNLDLRNFVYKTLLPAEASSLLRALLDVVSSLSHLLPRAGRVLERLPAFLHEFKITALLDAPDFQQVGSNQARSSAIGSFQSLMKMVCKDQASFFSSSDTFLNLPRVHELLGDDKEKFNIPEDSTPFCLKLYQEILQSPNGALVWSFLKPVLHGKILYTPNTPEINKVIQKVNHTFDFVGKLKTLSETLLSASSIFQSSGNGQMLHQLQEALKNKFIRSFIKSQLHIDVGKLTEKLQIFGGKLDAMLNHTGAGRLRSLGRVLVDLASCVRLNRFRGLASAAALEATAQALLRKNTLLASIIFNSSLVGKNLSSESLQLPPQVTYSIRTSILYSMRTDLVKNPFWKFHPQSLPADGFKYNYIFVPLQDMIERAIISVQTGQEALDPATQAQAIPYPCHTSDLFLNNVGFFFPLIMMLTWMVSVASMVRKLVYEREIQLEEYMRMMGVHPAVHFLAWFLENVAVLTVSSAALALVLKVSGIFTYSSAWIVFLFLLDFAVSVVTLSYLLSALFSRASMAALCSSLLYTASFLPYIVLLVLHDQMGATLQTLLCLLSTTAFGQGVFFITFLEGQEAGIQWDNMYQSPEVAGMTFGWVCWMILFDSGLYFLCGWYLNSLIPGTFGLRKPWYFPFTASYWKDVCGLVMKRQSPASSKLFSSSENLDGQGSSLQNGKGELEGGSPGVVLLSVTKEHDRHKAGVWDLTLTFHRDQITALLGTNGAGKTTVISLLTGLYPPTSGTITVNGRSLQKDPSVVRAELGVCLQWDILFDRLTVLEHLMLFASLKALRGTRQELREQVHRTLQDVGLTPHQHQQARVLSGGTRRKLSIGIAFLGASGTVVLDEPTSGVDPCSRRGIWDILLKYRQGRTIIFTTHHLDEAEALSDHVAVLQRGRLRCSGPPASLTQAHAQGFRLTLSRQPSVPEADDLKDTACATSLIQTYLPQASLQSSSQGELSYVIPEGADRACFRGLFQALDQNLHQLCLTGYGLSDTTLEEVFLHLLQDSKKQPDTALSLESAPPEPGPGHHLPHLPLLADRTPAGTPLVRGGPLLLAQTTALLRKRLLHARRAWKGTISDLLLPVLFVALAMALFMVRPLAINYPPLKLALGHYDKAETYFFSSENDGLELTRVLLRKFGDQDPPCADLYPDLWRRIGWQDLLKCPNASTRAPYLTNRLGHRLLNLSGLPLEEYLLAPMEKPRLGGWSFGVQIPNQVQDTNSNMSKPQNLAKVWYNQKGFHSLPSYLNHLNNLILWRRLPPTADWRQYGITLYSHPYGGALLNEDKILESIRQCGVALCIVLGFSILSASIGSSVVQDRVTGAKRLQHVSGLGYRTYWLTHFLFDMLLYLVSVCLCVSVIMAFQLTAFTFRENLAATALLLVLFGYATLPWMYLVSRIFSSSDVAFISYISLNFIFGLCTMLMTVMPRLLAIVSKAQNLQNIYDVLKWVFTIFPQFCLGQGLIELCYNQIRYDLTHNFGVDSYVSPFEMNFLGWIFVQLAVQGSVLLLLRVLLHRDLWLQPRGHSAIQGTVTSSKDIDVEKEQVRVLKGRTSGDTLVLYNLSKSYRGFFKSTTAVQDISLGVRRGECFGLLGVNGAGKTTTFKMLTGDLPPSSGHAVVRTPTGEDVNLSLAGAAGIRIGYCPQQDALDELLTGWEHLHYYCCLHGIPKQSIPKVAGDLVRRLHLEAHVDKPVATYSGGTKRKLSTALALLGKPDLLLLDEPSSGMDPCSKRHLWEALRKEAEEGCAVVLSSHSMEECEAVCTRLAIMVHGSFRCLGSPQHIKNRFGDGYTVKIWLHKEVDQHSAVSDCLKLYFPGIQFKGQRLNLLEYHMPKRWVCLANLFRVLEDNKSFLNIRHYSINQTTLEQIFVNFATEQWQTPSPSELSAKCDHSRHLPV", "length": 4945, "header": "tr|E1BK38-1|E1BK38_BOVIN Isoform 1 of ATP binding cassette subfamily A member 13 OS=Bos taurus OX=9913 GN=ABCA13 PE=4 SV=4 CANONICAL=E1BK38-1" }, "locus": { "chromosome": "4", "start_pos": 7578634, "end_pos": 7205763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061018.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061018.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053807.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053807.4" } ] } }, { "isoform_ac": "E1BM08-1", "url": "https://www.uniprot.org/uniprotkb/E1BK38/entry#E1BM08-1", "sequence": { "sequence": "MGRAGRQFRALVWKNWLCRVRHRVLSLAEFFWPCILFMILTVLRFQEPPRHRDNCYLQPRDLPSRGVFPFVQGLLCNTGSRCRNTSYEGAMEQRFRLSLFSSAPHQKVDNLAFLKEIQDLAQEVYEVMDKARNLQKLWAERSKTPGNCCGPAPPRLPHGVLFHQMDLNKTEEVIEKLESLHQQPHLWDFLLLLPRLYTNTFHVADGVLAGGHLLHAVLTSLSALEDLDWLPLNHTFFRVSEMVLKAAVSTLASLQESGAVATESGYSLSVKELMWDPQKVQADLKSQFGFDDLHAERVLNYSADLDEIPTDGSLEQMLCSALSGSSEDEDDGEGRPADCDPQWSAAKDYLVQAVSRLHLYRQVFDQQWKGSLFQQVLAGIGRGLEALRTQSGEGSQPWKVVRALQAAFLLLNDSMAADGPEGSHTPTRILLYMQRLQRVLRKLPPGPALMRLLQLDGALRNAGAQDLHLVRGNYVSAGRADSKPPDTCRVSMLYLPFQSHLLQAAITGHTSMPVSIPEDAPDWQDLGAQLQEASLPCTRLLRLLRADVSAADCADQLFSTVMFHTLEKAQSFLEHTHFWKAFMGFIRKTCEVARYVNKQEGIQNSSLGFSEESPCYKENMDWKSISGNYFAFLNNLFRTPTASMSRVLNYTKELLVMEKKLQTHKDEQINFLLSFMEFLEKLLPNPFNLSSILKFYNLPSVPEMTLNTSHLWLNHSASLGRDIPGMDTQKLLEVSKEMIEKIETHESFWIRKESINILRFVELMLLGMNPKFLAFWMHGASKEKRAELGLLPALANLSDSENEMIHRKSFNFSQLFHSDWPQSPAMKMDFVHVIEVIINSLYEFGFLSQEQVSETVDTLYAMRNASSLFLALSEPQKQDIEKILTCVYLHVFQDKDSALLLQIYSSFHQYMYKFMSIQSRESLLFLLMQISKHILDILKQFNFQNINKAFSFLYETTGVLGRISEVPYCQQLLSIFNFLELQAQSLVSTEGPAMEVIHATLRGLKHLFMVDDGFRNSVFQYVSQLFNGSAEALLGDECFVLDNKSISSANYSPAEGSPFILPWAQILSNFPADGSEFHEFTALHCTTLWLHTWTEVCGHIAQIFQLDTNVFTPLRVGLSQLLDELESDEKIPTSCQEVIPNRHPARLILHLFKNVTQTDGFRDWNDFLNLRDLWVALGDGFVRVKLLNLDQIEKSLFTMETTLSQLKSLDTNTSREFLYSLLNIFIELSNTSASIDRSVHLMNHFLLRNLTNYEVKFASVITDLRDTVLFLKNMSHNQDLLSCADIFQNVTEFILEDGLLYENSSQRAFHILAMLNSTFSSVDIVSRLKGCATWVSAINHLCAVYNSSFSQGHLHGVLQSLREVKDKLNSTLKLVTGMLTIMMEPCSLNRSHINCVNVYLKNVTDFLNILLTAVFGKEKVPHFEILLTLLNDSTNQVRMIINNVSRDFDFVPQSNWTHFTELILKPIEMSDEMPLQFQNIWLQLVALGKEIQNLVKDISPNNLENNTSYKAEKNLNIIATSPKEKDIHSLGNSFYQLASYLTFNLSHDLQSSPKIISQEVMKAVGLSIQLMKDLFNSLKPSAYHNIPQEPGDLQILKKMTSVLHTVKKTDIYLLVDQLEHISESMMDFFKNISRLGASNLGIGFFVDLMEKFVNSSHSWSINHLLRLSRLFPKKGADSLVDVYYMLPHAMRLLRGMGNKNITEALRDVYNFTLLHGIHLSDVTKEDFTAAIKTLMDTIESVSAQPGILSETLACLPVFWCWNHTTSGFQQNPRSDACNAHKLTSSFYSKVASILDHLHLSPHGDDSQCLNESSQMEITRKVACVIHELMDWSSILLELCEVFHIKTPLVKSVQEFWHKVLPFVQLSGNQSSGGISELCPGHLIKQVALPIIEKFKNFNFTKVTSDENLLEKLVSLNKVLNVDEGADTSVRYNISFRLKRITDFLSRKENLVNSTNSLVSPFMTLLNANLTGSSLEALSCFIKKSKAAYNLEKQWLEFEQIMKDITHNFSIRPLYSKIDNMIQRTSSVALQNITLPLAHFLESLDLSSLKTLEIIEDFLLVIKNWFHKFANEDYSKMIQTLFLLLANKSSTDDIALVTKDIATFLGYLKNVSREGNFDVALLTRLLSQEQLTNFSVVQLLFESFLINSVNDLAERSQGAALNLSDADLQIMNLINLVLNHTQSENGERVVFPPRSRMGFMEQLLKTFFFLLKENSGKKIFLLLKDIHKDLFAEMSFVPKDKILENLKLNHFLTSMKEDRLVSAFSTLKETVYHLIKNSFTLDDGELYFDNHQGLQLLGDLFHTLLRETSMKNETENDLEFLMVLNQLLSHMNSSEDLFKLNQDLRSALHLVRETSIVIAHFMDTLLSSPVKDFRVLYPSLQEVILANLTDLLSFVNNSFPLRNRATLEITRHLLGVISGAGGGNCTPDPLLEMSDTLTMLADDGVEMKGLATSVTSTVKFLKLAKKIARKVATMFQTHLISIANDTMKFFDTLYFLLLQSVRNVVNEMITLKKADHLIFENIDDLLMLFLDLAFGMIGVKPNISQDSDILNMSSGIFTYMNQSKHLYDIREEIADFLTSVKINLGDVERLLAAFKNGAQIFSVDSVNLWEEILDCLVLINNITSHIDFLYSNPTSTHNFPRDTKWEITHEVILFLREILSQNRTELGSYLRTVINLISVTLWNDTGKDHRGVLNLLLTLAPHPDDLLKLIRTAAEASCEASLFNTSWIQNVTEQQLQEAIQTLLRKIALVKKELLLNSSQWTHSMSTLLQPFFEIFIHATTGTHEKTQKELVDIPNILKPLSHFEKYRKALIALVEYWQRVSAEENCILMASLCVSSAENHSLTKDVLCAALHCEQSVARLLLLAALRAVVLGHDHYQELEKIWTSPHQLSCEGLHRNLSRALESFRSSLEDASEQDCECQSGSSLTDVKVKDLMQNISKLTEELRSSLHISDGTINSILEANISHSKVLPSVLTVALSGSCNRDILQLLLQFPEDGKSESAARELCGLPRAQVFSMIVVLARNLDLRNFVYKTLLPAEASSLLRALLDVVSSLSHLLPRAGRVLERLPAFLHEFKITALLDAPDFQQVGSNQARSSAIGSFQSLMKMVCKDQASFFSSSDTFLNLPRVHELLGDDKEKFNIPEDSTPFCLKLYQEILQSPNGALVWSFLKPVLHGKILYTPNTPEINKVIQKVNHTFDFVGKLKTLSETLLSASSIFQSSGNGQMLHQLQEALKNKFIRSFIKSQLHIDVGKLTEKLQIFGGKLDAMLNHTGAGRLRSLGRVLVDLASCVRLNRFRGLASAAALEATAQALLRKNTLLASIIFNSSLVGKNLSSESLQLPPQVTYSIRTSILYSMRTDLVKNPFWKFHPQSLPADGFKYNYIFVPLQDMIERAIISVQTGQEALDPATQAQAIPYPCHTSDLFLNNVGFFFPLIMMLTWMVSVASMVRKLVYEREIQLEEYMRMMGVHPAVHFLAWFLENVAVLTVSSAALALVLKVSGIFTYSSAWIVFLFLLDFAVSVVTLSYLLSALFSRASMAALCSSLLYTASFLPYIVLLVLHDQMGATLQTLLCLLSTTAFGQGVFFITFLEGQEAGIQWDNMYQSPEVAGMTFGWVCWMILFDSGLYFLCGWYLNSLIPGTFGLRKPWYFPFTASYWKDVCGLVMKRQSPASSKLFSSSENLDGQGSSLQNGKGELEGGSPGVVLLSVTKEHDRHKAGVWDLTLTFHRDQITALLGTNGAGKTTVISLLTGLYPPTSGTITVNGRSLQKDPSVVRAELGVCLQWDILFDRLTVLEHLMLFASLKALRGTRQELREQVHRTLQDVGLTPHQHQQARVLSGGTRRKLSIGIAFLGASGTVVLDEPTSGVDPCSRRGIWDILLKYRQGRTIIFTTHHLDEAEALSDHVAVLQRGRLRCSGPPASLTQAHAQGFRLTLSRQPSVPEADDLKDTACATSLIQTYLPQASLQSSSQGELSYVIPEGADRACFRGLFQALDQNLHQLCLTGYGLSDTTLEEVPADERYSNLPHLPLLADRTPAGTPLVRGGPLLLAQTTALLRKRLLHARRAWKGTISDLLLPVLFVALAMALFMVRPLAINYPPLKLALGHYDKAETYFFSSENDGLELTRVLLRKFGDQDPPCADLYPDLWRRIGWQDLLKCPNASTRAPYLTNRLGHRLLNLSGLPLEEYLLAPMEKPRLGGWSFGVQIPNQVQDTNSNMSKPQNLAKVWYNQKGFHSLPSYLNHLNNLILWRRLPPTADWRQYGITLYSHPYGGALLNEDKILESIRQCGVALCIVLGFSILSASIGSSVVQDRVTGAKRLQHVSGLGYRTYWLTHFLFDMLLYLVSVCLCVSVIMAFQLTAFTFRENLAATALLLVLFGYATLPWMYLVSRIFSSSDVAFISYISLNFIFGLCTMLMTVMPRLLAIVSKAQNLQNIYDVLKWVFTIFPQFCLGQGLIELCYNQIRYDLTHNFGVDSYVSPFEMNFLGWIFVQLAVQGSVLLLLRVLLHRDLWLQPRGHSAIQGTVTSSKDIDVEKEQVRVLKGRTSGDTLVLYNLSKSYRGFFKSTTAVQDISLGVRRGECFGLLGVNGAGKTTTFKMLTGDLPPSSGHAVVRTPTGEDVNLSLAGAAGIRIGYCPQQDALDELLTGWEHLHYYCCLHGIPKQSIPKVAGDLVRRLHLEAHVDKPVATYSGGTKRKLSTALALLGKPDLLLLDEPSSGMDPCSKRHLWEALRKEAEEGCAVVLSSHSMEECEAVCTRLAIMVHGSFRCLGSPQHIKNRFGDGYTVKIWLHKEVDQHSAVSDCLKLYFPGIQFKGQRLNLLEYHMPKRWVCLANLFRVLEDNKSFLNIRHYSINQTTLEQIFVNFATEQWQTPSPSELSAKCDHSRHLPV", "length": 4885, "header": "tr|E1BM08-1|E1BM08_BOVIN Computationally mapped isoform of ATP binding cassette subfamily A member 13 OS=Bos taurus OX=9913 GN=ABCA13 PE=4 SV=2 CANONICAL=E1BK38-1" }, "locus": { "chromosome": "4", "start_pos": 7598351, "end_pos": 7205763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034269.7", "url": "https://www.ensembl.org/id/ENSBTAT00000034269.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034167.5", "url": "https://www.ensembl.org/id/ENSBTAP00000034167.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of synaptic vesicle endocytosis", "id": "GO:1900244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900244", "evidence": [ { "database": "UniProtKB", "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ], "pmid": "" }, { "name": "ceramide transport", "id": "GO:0035627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035627", "evidence": [ { "database": "UniProtKB", "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ], "pmid": "" }, { "name": "positive regulation of cholesterol transport", "id": "GO:0032376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032376", "evidence": [ { "database": "UniProtKB", "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "E1BK38", "url": "https://www.uniprot.org/uniprotkb/E1BK38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1033, "end_pos": 1035, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1049, "end_pos": 1051, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1056, "end_pos": 1058, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1160, "end_pos": 1162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1218, "end_pos": 1220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"header": "tr|E1BK64-1|E1BK64_BOVIN Isoform 1 of Pejvakin OS=Bos taurus OX=9913 GN=PJVK PE=3 SV=1 CANONICAL=E1BK64-1" }, "locus": { "chromosome": "2", "start_pos": 18435911, "end_pos": 18429705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056768.4", "url": "https://www.ensembl.org/id/ENSBTAT00000056768.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048503.2", "url": "https://www.ensembl.org/id/ENSBTAP00000048503.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:618114", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618114", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LPX0-1", "protein_name": "Pejvakin isoform X1", "gene_name": "Pjvk", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"header": "tr|E1BKA0-1|E1BKA0_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC4 PE=3 SV=4 CANONICAL=E1BKA0-1" }, "locus": { "chromosome": "25", "start_pos": 38417765, "end_pos": 38410505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012560.8", "url": "https://www.ensembl.org/id/ENSBTAT00000012560.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012560.7", "url": "https://www.ensembl.org/id/ENSBTAP00000012560.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BKA0", "url": "https://www.uniprot.org/uniprotkb/E1BKA0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": 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"Protein Classification", "Other" ] }, { "id": "NP_001376911", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376911", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BKA2", "url": "https://www.uniprot.org/uniprotkb/E1BKA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKA2-1", "url": "https://www.uniprot.org/uniprotkb/E1BKA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKVNSSVVSEFVLLGLSSSQELQLFFFVFFSVLYMVIVLGNLLIILTVTSDSSLHSPMYFLLGNLSFVDICQASFATPKMIADFLSEHKTISFSGCIAQIFFIHLFTGGEMMLLVSMAYDRYVAICKPLHYVIIMRRRTCTVLVMISWAVGLVHTLSQLSFTVNLPFCGPNVVDSFFCDLPRVTKLACLDSYITEILIVVNSGILSLSTFSLLVSSYIIILITVWFKSSAAMAKAFSTLAAHITVVILFFGPCIFIYVWPFTSYPVDKVLAIFYTIFTPILNPIIYTLRNRDMKIAFRKIMIHYSRAKKISERPVIVRNSVY", "length": 323, "header": "tr|E1BKA2-1|E1BKA2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4K5 PE=3 SV=2 CANONICAL=E1BKA2-1" }, "isoforms": [ { "isoform_ac": "E1BKA2-1", "url": "https://www.uniprot.org/uniprotkb/E1BKA2/entry#E1BKA2-1", "sequence": { "sequence": "MDKVNSSVVSEFVLLGLSSSQELQLFFFVFFSVLYMVIVLGNLLIILTVTSDSSLHSPMYFLLGNLSFVDICQASFATPKMIADFLSEHKTISFSGCIAQIFFIHLFTGGEMMLLVSMAYDRYVAICKPLHYVIIMRRRTCTVLVMISWAVGLVHTLSQLSFTVNLPFCGPNVVDSFFCDLPRVTKLACLDSYITEILIVVNSGILSLSTFSLLVSSYIIILITVWFKSSAAMAKAFSTLAAHITVVILFFGPCIFIYVWPFTSYPVDKVLAIFYTIFTPILNPIIYTLRNRDMKIAFRKIMIHYSRAKKISERPVIVRNSVY", "length": 323, "header": "tr|E1BKA2-1|E1BKA2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4K5 PE=3 SV=2 CANONICAL=E1BKA2-1" }, "locus": { "chromosome": "10", "start_pos": 27301815, "end_pos": 27300847, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000590.6", "url": "https://www.ensembl.org/id/ENSBTAT00000000590.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000590.5", "url": "https://www.ensembl.org/id/ENSBTAP00000000590.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:516054", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516054", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSD7-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSTNYSVVSEFVLLGLSRSRELQIFYFVFFSALYIVIVLGNLLIIIAVTSDSSLHSPMYFLLGNLSFFDICQASFATPKMIVDFLSERKTISFTGCIAQIFFIHLFTGGEMVILVSMAYDRYVAICKPLHYMIIMNHSTCTALVLISWAVGLIHTLSQLSFTVKLAFCGPNEVDSFFCDLPRVVKLACIDSYITEILIVVNSGILSLSTFSLLVSSYVIILVTVWFKSSAAMAKAFSTLAAHIMVVVLFFGPCIFIYVWPFTTYPVDKFLAIFYTVFTPILNPIIYTLRNRDMKAVMGKIAAQYLRPPKIAEMPFVTRIPHD", "length": 323 }, "evidence": [ { "id": "E1BKA2", "url": "https://omabrowser.org/oma/group/E1BKA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3ID33-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100752775", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDKINYSVVSEFVLLGLSSSQELQYFFFVFFSALYIAIVLGNLLIIMAVTSDSSLHSPMYFLLGNLSFFDICQASFATPKMIADFLSEHKTISFSGCIAQIALIHLFTGGEMVLLVSMAYDRYVAICKPLHYMSIMNRSTCTALVIISWAVGLVHTLSQLSFTVTLVFCGPNEVDSFFCDLPRVAKLACLDSYNTEILIVVNSGILSLSTFSLLVTSYAIVLVTVWFKSSAAMAKAFSTLAAHIMVVVLFFGPCIFIYVWPFTTYPVDKILAIFYTVFTPILNPIIYTLRNRDMKVAMGKIAARYFRPPKISEMPLVARISLH", "length": 323 }, "evidence": [ { "id": "E1BKA2", "url": "https://omabrowser.org/oma/group/E1BKA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8NGD3-1", "protein_name": "Olfactory receptor 4K5", "gene_name": "OR4K5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDKSNSSVVSEFVLLGLCSSQKLQLFYFCFFSVLYTVIVLGNLLIILTVTSDTSLHSPMYFLLGNLSFVDICQASFATPKMIADFLSAHETISFSGCIAQIFFIHLFTGGEMVLLVSMAYDRYVAICKPLYYVVIMSRRTCTVLVMISWAVSLVHTLSQLSFTVNLPFCGPNVVDSFFCDLPRVTKLACLDSYIIEILIVVNSGILSLSTFSLLVSSYIIILVTVWLKSSAAMAKAFSTLASHIAVVILFFGPCIFIYVWPFTISPLDKFLAIFYTVFTPVLNPIIYTLRNRDMKAAVRKIVNHYLRPRRISEMSLVVRTSFH", "length": 323 }, "evidence": [ { "id": "E1BKA2", "url": "https://omabrowser.org/oma/group/E1BKA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VET4-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNTNYSVVSEFVLLGLSSSRELQIFYFVFFSMLYIVIILGNLLIIIAVTSDSSLHSPMYFLLGNLSFFDICQASFATPKMIVDFLSEHKTISFSGCIAQIFFIHLFTGGEMVILVSMAYDRYVAICKPLHYMTIMNQTTCTALVVISWAVGLVHTLSQLSFTVKLSFCGPNEVDSFFCDLPRVVKLACIDSYITEILIVVNSGILSLSTFSLLVSSYVIILVTVWFKSSAAMAKAFSTLAAHIMVVVLFFGPCIFIYVWPFTTYPVDKILAIFYTVFTPILNPIIYTLRNRDMKAVMGKIAAHYLRPPKVAEMSFVARISLY", "length": 323 }, "evidence": [ { "id": "E1BKA2", "url": "https://omabrowser.org/oma/group/E1BKA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BKA2", "url": "https://www.uniprot.org/uniprotkb/E1BKA2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "E1BKA2", "url": "https://www.uniprot.org/uniprotkb/E1BKA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BKA2", "url": "https://www.uniprot.org/uniprotkb/E1BKA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "E1BKA2", "url": "https://www.uniprot.org/uniprotkb/E1BKA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKA2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 323, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKA2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKA2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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{ "uniprot_canonical_ac": "E1BKA6-1", "uniprot_ac": "E1BKA6", "uniprot_id": "E1BKA6_BOVIN", "mass": { "chemical_mass": 36114.0, "monoisotopic_mass": 36114.0 }, "refseq": { "ac": "NP_001179489", "name": "GRB2-related adapter protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179489" }, "gene_names": [ { "name": "GRAP2", "type": "recommended", "evidence": [ { "id": "E1BKA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA6" } ] }, { "name": "GRAP2", "type": "synonym", "evidence": [ { "id": "NP_001179489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179489" } ] } ], "protein_names": [ { "name": "Adapter protein GRID", "type": "recommended", "evidence": [ { "id": "E1BKA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA6/entry#names_and_taxonomy" } ] }, { "name": "GRB-2-like protein", "type": "synonym", "evidence": [ { "id": "E1BKA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA6/entry#names_and_taxonomy" } ] }, { "name": "GRB2-related adapter protein 2", "type": "synonym", "evidence": [ { "id": "NP_001179489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179489" } ] }, { "name": "GRBLG", "type": "synonym", "evidence": [ { "id": "E1BKA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA6/entry#names_and_taxonomy" } ] }, { "name": "Growth factor receptor-binding protein", "type": "synonym", "evidence": [ { "id": "E1BKA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.", "evidence": [ { "database": "UniProtKB", "id": "E1BKA6", "url": "https://www.uniprot.org/uniprotkb/E1BKA6#function" }, { "database": "UniProtKB", "id": "ARBA00055397", "url": "https://www.uniprot.org/uniprotkb/ARBA00055397#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKA6", "url": "https://www.uniprot.org/uniprotkb/E1BKA6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GRAP2", "url": "https://www.uniprot.org/uniprotkb/E1BKA6", "locus": { "chromosome": "5", "start_pos": 111329318, "end_pos": 111309840, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015157", "url": "https://www.ensembl.org/id/ENSBTAG00000015157" } ] } } ], "crossref": [ { "id": "E1BKA6", "url": 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"IPR035646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:522346", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522346", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VAKFDFM", "url": "https://omabrowser.org/oma/group/VAKFDFM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKA6", "url": "https://www.orthodb.org/?gene=E1BKA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1433557", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1433557", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-202433", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-202433", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2424491", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2424491", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2871796", "url": 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Adapter protein GRID OS=Bos taurus OX=9913 GN=GRAP2 PE=3 SV=1 CANONICAL=E1BKA6-1" }, "locus": { "chromosome": "5", "start_pos": 111329128, "end_pos": 111309895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020161.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020161.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020161.5", "url": "https://www.ensembl.org/id/ENSBTAP00000020161.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:522346", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522346", "resource": "KEGG Pathway" }, { "id": "R-BTA-1433557", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1433557", "resource": "Reactome", "description": "Signaling by SCF-KIT" }, { "id": "R-BTA-202433", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-202433", "resource": "Reactome", "description": "Generation 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BKA6", "url": "https://www.uniprot.org/uniprotkb/E1BKA6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BKA6", "url": "https://www.uniprot.org/uniprotkb/E1BKA6" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "E1BKA6", "url": "https://www.uniprot.org/uniprotkb/E1BKA6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BKA6", "url": "https://www.uniprot.org/uniprotkb/E1BKA6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": 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"MWAPHGLSKNRALRYQPPPGTQLEAEWAHGHSTYPVTEKPSEGKVWAQAHQQVKPIWRLEKKHVGTLSAGLGPGLLGAPPQPAYFFCPSTLCSSGTTAVTAGHSNCCYLHSLPDLFSSTLLYRRSNYRHKAYQQLESFCLRSSPSEKRPFSLPQKRLPVRLPANKATSSKLIPMASSSTEPYSSLGAAGESLSGRSLASAISGKTPSPLPSSSSSYKPMLNNNSFMRPNSTKVPLSQATEGLKPVSSPKVQLISWQHSGGTGDCAFQSVEHKAPKSSGPALDDAPPHNMLSTPSSLDTSATSVASSFYSQSNLVTRTQSYPYGLKGDPVSQTLTKEVRFTEAVRKLTARGLEKKPRQGYHFEQTYFMNPSLQWDLLNQNRRWKPPVASQQVPQEDAGADNRALPAVSDPGGLDSAVFCTKRISIHLLASHTNGLSYSPACGSTIDSPLLGEDKTPVPPSPSQPLGVAEVATRLSSIHLGKLGREGPKEARELNSPPRTVGSATDLQLDPVETEDLEEELLDGLEDCCSQVENEEEEGDSECSSCSAVSPSESVAVISRNCMEFLTKPLSNEKVVRPALIYSLFPNVPPTIYFGTPDERVEKLPWEQRKLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMKSPSFRSIQEHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKLLRKAWESGSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANEDETACQGHKWALKALWSYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCHELFGFDVMLDEKLKPWVLEVNISPSLHSNSPLDISIKGQMIRDLLNLAGFVLPNADDIASSSSSSSSSTTSLPSSPRDRCRVAPEYFTAQKMKKAYYLTQKIPDQDFYASVLDVLTPDDVRVLVEMEDEFSRRGQFERIFPSRISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRSWCYKGFHTGAISDSAPVWTLPASVLTVPKADATLSDFSKPETVKLRKHGSTERNIPLSEDGTMPKLKKTQAGLSSPPRKLSSSEDSEDTSKEPSLSTQLLPVIKFSGQTSRLSASTSSQSAGGSLLAAVSL", "length": 1203, "header": "tr|E1BKB4-1|E1BKB4_BOVIN Isoform 1 of Tubulin tyrosine ligase like 4 OS=Bos taurus OX=9913 GN=TTLL4 PE=3 SV=2 CANONICAL=E1BKB4-1" }, "isoforms": [ { "isoform_ac": "E1BKB4-1", "url": "https://www.uniprot.org/uniprotkb/E1BKB4/entry#E1BKB4-1", "sequence": { "sequence": "MWAPHGLSKNRALRYQPPPGTQLEAEWAHGHSTYPVTEKPSEGKVWAQAHQQVKPIWRLEKKHVGTLSAGLGPGLLGAPPQPAYFFCPSTLCSSGTTAVTAGHSNCCYLHSLPDLFSSTLLYRRSNYRHKAYQQLESFCLRSSPSEKRPFSLPQKRLPVRLPANKATSSKLIPMASSSTEPYSSLGAAGESLSGRSLASAISGKTPSPLPSSSSSYKPMLNNNSFMRPNSTKVPLSQATEGLKPVSSPKVQLISWQHSGGTGDCAFQSVEHKAPKSSGPALDDAPPHNMLSTPSSLDTSATSVASSFYSQSNLVTRTQSYPYGLKGDPVSQTLTKEVRFTEAVRKLTARGLEKKPRQGYHFEQTYFMNPSLQWDLLNQNRRWKPPVASQQVPQEDAGADNRALPAVSDPGGLDSAVFCTKRISIHLLASHTNGLSYSPACGSTIDSPLLGEDKTPVPPSPSQPLGVAEVATRLSSIHLGKLGREGPKEARELNSPPRTVGSATDLQLDPVETEDLEEELLDGLEDCCSQVENEEEEGDSECSSCSAVSPSESVAVISRNCMEFLTKPLSNEKVVRPALIYSLFPNVPPTIYFGTPDERVEKLPWEQRKLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMKSPSFRSIQEHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKLLRKAWESGSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANEDETACQGHKWALKALWSYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCHELFGFDVMLDEKLKPWVLEVNISPSLHSNSPLDISIKGQMIRDLLNLAGFVLPNADDIASSSSSSSSSTTSLPSSPRDRCRVAPEYFTAQKMKKAYYLTQKIPDQDFYASVLDVLTPDDVRVLVEMEDEFSRRGQFERIFPSRISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRSWCYKGFHTGAISDSAPVWTLPASVLTVPKADATLSDFSKPETVKLRKHGSTERNIPLSEDGTMPKLKKTQAGLSSPPRKLSSSEDSEDTSKEPSLSTQLLPVIKFSGQTSRLSASTSSQSAGGSLLAAVSL", "length": 1203, "header": "tr|E1BKB4-1|E1BKB4_BOVIN Isoform 1 of Tubulin tyrosine ligase like 4 OS=Bos taurus OX=9913 GN=TTLL4 PE=3 SV=2 CANONICAL=E1BKB4-1" }, "locus": { "chromosome": "2", "start_pos": 106705748, "end_pos": 106689293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069658.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069658.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062435.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062435.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 100, "start_aa": "Thr", "end_pos": 100, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr100", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IBS5-1", "protein_name": "Tubulin polyglutamylase TTLL4 isoform X1", "gene_name": "Ttll4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASAGTEHYNIGLRRGNSFKQRRPSGTVSASSPEKPSEVKVWSQAHQQVKPIWKLERKHVGTLSAGLGTSLLGVQPQPAYFFCPSTLCNSGTTAVIAGHSNPCYLQSLPDLFNNTLLYRRTNVRQKPYQQLESFCLRSSPSEKRSFSFSQKGIPVSVTANKVTSSTVFPMAQPMASSPTDPYLSLAAAGENPSRKSLSSAISGKIASPLSSYKPMLNNNSFMRPNSTKVPLSQATDGLKPVSSPKIQPVSWHHSGGTGDCVPQPGDHKVPQSIGTILDDSTAPDTPSTPSTLNISTASVPSSQCSQSNFRMEAHPCGLDENLDSHSATKEVHFTEAVRKLTAKGFEKMPRQGYQFEQACFVNPSFQWGLLNRSRRWKPLMGQRFPQEDTGLDSEILPGASDTLGLDSTVFCTKRISIHLLASHVHGLNPSPTCGSVVDPQSFGEDRTPVPPSSLQPLDVAEVATRLSSVHLGQPEKEPEEAKELSSCPISRCSATDLRPNQVEPEDTEDELGDGLEDCCSHGENEEEEGNSECSSLSIISPSESVAIISRNCVDLMSKSLPSHEKVVRPALIYSLFPNVSPTIYFGTRDERVEKLPWEQRKLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMKSPGFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKLLRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLSNKFMHLTNYSVNKKNVEYQSNADETACQGHKWALKALWNYLSQKGINSDAIWEKIKDVVVKTIISSEPYVTNLLKLYVRRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSNSPLDISIKGQMIRDLLNLAGFVLPNMEDILSSSSSTSSTSSSSTSLPSSPRDKCQMTPEHFTAQKMKKAYYLTQKIPDQDFYASVLDVLTPDDVRVLVEMEDEFSRRGQFERIFPSRISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRNWCYKGFHTGIVSDSAPLWSLPTSIMTASKGDGTPSAISKLERIKSRKQSCSEGNMLSSEDGILPKPKKSHAGLSPLSRKISSSKNNEDTSKESNHSTQVLPVLKYSGHNSRLCASSTSQSASDSLLTAVSL", "length": 1199 }, "evidence": [ { "id": "E1BKB4", "url": "https://omabrowser.org/oma/group/E1BKB4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A331-1", "protein_name": "Tubulin tyrosine ligase like 4", "gene_name": "Ttll4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASAGTEHYSIGLRRGNSFKQRQPSGTVSASPSEKPSEVKVWSQAHQQVKPIWKLERKHVGTLSAGLGTSLLGVPPQPAYFFCPSTLCSSGTTAVIAGHSNPCYLQSLPDLFSNTLLYRRTNVRQKPYQQLESFCLRSNPSEKRSFSLPQKGLPVSVTANKATSSTVFPMAQPMASSPTDPYLSLAAAGENPSRKSLSSAISGKIASPLSSYKPMLNNNSFMRPNSTKVPLSQATDGLKPVSSPKIQPVSWHHSGGTGDCVPQPGDHKVPQSIATVLDDVTAPMAPSTPSTLNISTASVASSQCSQSNFRREAHPCGLDENTDSQSATKEVHFTEAVRKLAAKGFEKMPRQGYQFEQACFVNPSFQWGLLNRSRRWKPLMGQRFPQEDIGLDSGILPGASDTLGLDSTVFCTKRISIHLLASHVHGLNPSPTCGSVVDPQLLGEDRAPVPPSSSLQPLGVAEVATRLSSVHLGQPGKEPEEAKDLNSCSTKGDCSPTDLRPKQLEPEDSEDELGDGLEDSCSHDENEEEEGDSECSSLSVVSPSESVAIISRNCVDLMSKSISNHEKVVRPALIYSLFPNVSPTIYFGTRDERVEKLPWEQRRLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMKSPGFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDSKLLRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLSNKFMHLTNYSVNKKNAEYQANADETACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTNLLKLYVRRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSNSPLDISIKGQMIRDLLNLAGFVLPNMEDILSSSSSPSSSSGSSTSLPSSPREKCQMTPEHFTAQKMKKAYYLTQKVPDQDFYSSVLDVLTPDDVRVLVEMEDEFSRRGQFERIFPSRISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRNWCYKGFHTGIVSDSAPLWSLPTSLMNASKGDGTPNAVSRSDHNKSRKKSCSEGNSEDGPTSKPKKSQAGLSPISRKTLSSKNNENTSKQSKRSTQGLPVLKYSGQGSRLSASSASQSIADSLLTAVSP", "length": 1198 }, "evidence": [ { "id": "E1BKB4", "url": "https://omabrowser.org/oma/group/E1BKB4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14679-1", "protein_name": "Tubulin monoglutamylase TTLL4", "gene_name": "TTLL4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASAGTQHYSIGLRQKNSFKQSGPSGTVPATPPEKPSEGRVWPQAHQQVKPIWKLEKKQVETLSAGLGPGLLGVPPQPAYFFCPSTLCSSGTTAVIAGHSSSCYLHSLPDLFNSTLLYRRSSYRQKPYQQLESFCLRSSPSEKSPFSLPQKSLPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKSLASAISGKIPSPLSSSYKPMLNNNSFMWPNSTPVPLLQTTQGLKPVSPPKIQPVSWHHSGGTGDCAPQPVDHKVPKSIGTVPADASAHIALSTASSHDTSTTSVASSWYNRNNLAMRAEPLSCALDDSSDSQDPTKEIRFTEAVRKLTARGFEKMPRQGCQLEQSSFLNPSFQWNVLNRSRRWKPPAVNQQFPQEDAGSVRRVLPGASDTLGLDNTVFCTKRISIHLLASHASGLNHNPACESVIDSSAFGEGKAPGPPFPQTLGIANVATRLSSIQLGQSEKERPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEEEEGDSECSSLSAVSPSESVAMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPPTIYFGTRDERVEKLPWEQRKLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMKSPSFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKLLRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLPNAEDIISSPSSCSSSTTSLPTSPGDKCRMAPEHVTAQKMKKAYYLTQKIPDQDFYASVLDVLTPDDVRILVEMEDEFSRRGQFERIFPSHISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRSWCYKGFHMGVVSDSAPVWSLPTSLLTISKDDVILNAFSKSETSKLGKQSSCEVSLLLSEDGTTPKSKKTQAGLSPYPQKPSSSKDSEDTSKEPSLSTQTLPVIKCSGQTSRLSASSTFQSISDSLLAVSP", "length": 1199 }, "evidence": [ { "id": "E1BKB4", "url": "https://omabrowser.org/oma/group/E1BKB4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80UG8-1", "protein_name": "Tubulin monoglutamylase TTLL4", "gene_name": "Ttll4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASAGTEHYSIGLRRGNSFKQRHPSGTVSASPSEKPSEVKVWSQAHQQVKPIWKLEKKHVGTLSAGLGTSFLGVPSQPAYFLCPSTLCSSGTTAVIAGHSNPCYLQSLPNLFSNTLLYRRTNVRQKPYQQLESFCLRSSPSEKRSFSLPQKGLPVSVTANKATSSTVFPMAQPMATSPTDPYLSLAAAGENPSRKSLASAISGKIASPLSYKPMLNNNSFMRPNSTKVPLSQATDGLKPVSSPKIQPVSWHHSGGTGDCVPQPGDHKVPQNIATVLDDVTAPITPSIPSTLNISTASVTSSQCSQSNFRMEAHPCGLDENPDSQSATKEVHFTEAVRKLAEKGLEKMPRQGYQFEQACFVNPSFQWGLLNRSRRWKPLMGQRFPQEDIGLDSAILPGTSDTLGLDSTVFCTKRISIHLLASHVHGLNPSPACGSAVDPQVLGEDRAPVPPSSLQPLGVAEVATRLSSVHLDQPGKEPEEAKDLNSCTKGGGSATDLQPNQVEPEDTEDELGDGLEDSCSHDENEEEEGDSECSSLSVVSPSESVALISRNCVDLMSKSLPNHEKVVRPALIYSLFPNVTPTIYFGTRDERVEKLPWEQRRLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMKSPGFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDSKLLRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLSNKFMHLTNYSVNKKNTEYQANADETACQGHKWALKALWNYLSQKGINSDAIWEKIKDVVVKTIISSEPYVTNLLKLYVRRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSNSPLDISIKGQMIRDLLNLAGFVLPNMEDIISSSSSPSSSSGSSTSLPSSPRDKCQMTPEHFTAQKMKKAYYLTQKIPDQDFYASVLDVLTPDDVRVLVEMEDEFSRRGQFERIFPSRISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRNWCYKGFHTGIVSDSAPLWSLPTSLMTTSKGDGTPNSASKSRKKSASEGTTLSSEDRSTPKSKKSQAGLSPISRKTLSSRSNENTSKQSKRSTPGLPVLKYSGQSSRLSAASASQSVTDSRLTAVSS", "length": 1193 }, "evidence": [ { "id": "E1BKB4", "url": "https://omabrowser.org/oma/group/E1BKB4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tubulin-glutamic acid ligase activity", "id": "GO:0070740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070740", "evidence": [ { "database": "UniProtKB", "id": "E1BKB4", "url": "https://www.uniprot.org/uniprotkb/E1BKB4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BKB4", "url": "https://www.uniprot.org/uniprotkb/E1BKB4" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "E1BKB4", "url": "https://www.uniprot.org/uniprotkb/E1BKB4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "E1BKB4", "url": "https://www.uniprot.org/uniprotkb/E1BKB4" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "E1BKB4", "url": "https://www.uniprot.org/uniprotkb/E1BKB4" } ], "pmid": "" }, { "name": "9+0 non-motile cilium", "id": "GO:0097731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097731", "evidence": [ { "database": "UniProtKB", "id": "E1BKB4", "url": "https://www.uniprot.org/uniprotkb/E1BKB4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "E1BKB4", "url": "https://www.uniprot.org/uniprotkb/E1BKB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 911, "end_pos": 913, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKB4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1203, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKB4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKB4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 100 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 680, "end_pos": 682 }, { "start_pos": 813, "end_pos": 815 }, { "start_pos": 911, "end_pos": 913 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, 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"MLMNYSSATEFYLLGFPGSEELHHILFAIFFFFYLVTLMGNTVIIMIVCVDKRLQSPMYFFLGHLSALEILVTTIIVPVMLWGLLLPGMQTIYLSACVVQLFLYLAVGTTEFALLGAMAVDRYVAVCNPLRYNIIMNRHTCNFVVLVSWVFGFLFQIWPVYVMFQLTYCKSNVVNNFFCDRGQLLKLSCNNTLFTEFILFLMAVFVLFGSLIPTIVSNAYIISTILKIPSSSGRRKSFSTCASHFTCVVIGYGSCLFLYVKPKQTQAADYNWVVSLMVSVVTPFLNPFIFTLRNDKVIEALRDGVKRCCQLFRN", "length": 314 }, "evidence": [ { "id": "E1BKC1", "url": "https://omabrowser.org/oma/group/E1BKC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VF31-1", "protein_name": "Olfactory receptor", "gene_name": "Or9a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGNHTSATEFYLVGFPGSVNLRHILFATFCFFYLVTLVGNTVIIVIVCVDKRLQSPMYFFLVHLSILEILVTTVIVPVMLWGLLLPGMQSISLAGCVAQLFLQLALGTTEFSLLGAMAVDRYVAVCNPLRYSVIMNSRTCNSVVIVSWVFGFLFQIWPVYATFHLNYCKSNVVDNFFCDRGQLLKLSCNNTIFIEFILFLMAVFVLFGSLIPTIVSYTYIIATILKIPSASGRRKAFSTCASHFTCVVIGYGCCLFLYVKPKQTQAADYNRVVSLMISIVTPFLNPFIFTLRNDKVIEALRDGVKRCYHFFKS", "length": 314 }, 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"E1BKE4", "url": "https://www.orthodb.org/?gene=E1BKE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192877", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192877", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKE4-1", "url": "https://www.uniprot.org/uniprotkb/E1BKE4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHSLDEPLDLKLSITKLRAAREKRERTLSAARHRALHRELGLADDSPTPGSPGSPPSGFLLNPKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPTAPAGPDLQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPELPLPKQLVCRWAKCNQPFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQHELLQLRPPPKPPLPAPDGSPYVSGAQIIIPNPAALFGGPGLPGLPLPLAPGPLDLSALACGNGGGAGGAGGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGSAGGKAEGEKGRGAMPARALSSEGRKTPLERTEGSRSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN", "length": 524, "header": "tr|E1BKE4-1|E1BKE4_BOVIN Isoform 1 of Zinc finger protein GLIS2 OS=Bos taurus OX=9913 GN=GLIS2 PE=3 SV=1 CANONICAL=E1BKE4-1" }, "isoforms": [ { "isoform_ac": "E1BKE4-1", "url": "https://www.uniprot.org/uniprotkb/E1BKE4/entry#E1BKE4-1", "sequence": { "sequence": "MHSLDEPLDLKLSITKLRAAREKRERTLSAARHRALHRELGLADDSPTPGSPGSPPSGFLLNPKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPTAPAGPDLQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPELPLPKQLVCRWAKCNQPFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQHELLQLRPPPKPPLPAPDGSPYVSGAQIIIPNPAALFGGPGLPGLPLPLAPGPLDLSALACGNGGGAGGAGGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGSAGGKAEGEKGRGAMPARALSSEGRKTPLERTEGSRSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN", "length": 524, "header": "tr|E1BKE4-1|E1BKE4_BOVIN Isoform 1 of Zinc finger protein GLIS2 OS=Bos taurus OX=9913 GN=GLIS2 PE=3 SV=1 CANONICAL=E1BKE4-1" }, "locus": { "chromosome": "25", "start_pos": 3502271, "end_pos": 3497842, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012119.5", "url": "https://www.ensembl.org/id/ENSBTAT00000012119.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012119.3", "url": "https://www.ensembl.org/id/ENSBTAP00000012119.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 48, "start_aa": "Thr", "end_pos": 48, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr48", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:527935", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527935", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QHY8-1", "protein_name": "Zinc finger protein GLIS2", "gene_name": "GLIS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHSLDEPLDLKLSITKLRAAREKRERTLSAVRHRALHRELGLVDDSPTPGSPGSPPSGFLLNPKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLSAVPTGPDLQPLRYLDGVPSSFQFLLPLGSGGALHLPASSFLPPPKDKCLSPELPLPKQLVCRWAKCNQPFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGSPYVSGAQIIIPNPAALFGGPGLPGLPLPLAPGPLDLSALACGNGGGGGGAGGMGPGLPGPVLPLNLAKSPLLPSPFGAGGLGLPVVSLLAGSAGGKAEGEKGRGAMPARALGMEGRKTPLERTESSRSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN", "length": 524 }, "evidence": [ { "id": "E1BKE4", "url": "https://omabrowser.org/oma/group/E1BKE4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Z3B3-1", "protein_name": "Zinc finger protein GLIS2", "gene_name": "GLIS2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHSLDEPLDLKLSISKVRSAREKRERGPPGPRPRAVPPSAAAPPPVGESRGSARGGRRAGPGPGLLAHSKALEKRFPALPVMDLSLSPPPGVESPGGGSASLSPERHSDPPVPALPHDFQSLRYIDGIPGSFQFFLPLGAGGALHLPSFLPPPKDKRLSPELPLPKQLVCRWSKCNQFFDLLQDLVDHVNDFHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYICPYEGCNKRYSNSSDRFKHTRTHYVEKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEHHEMLKAHAPPKGSADAPYANGAQLLLPNPAALFAPHALPALPLPLAPAPLDLSALGCGAGGSLPALPGPALPLNGGGPLNLAKGPLLPSPFAAGGLGLPVMSLLAGGAKAEEAEGRKGGKEGRKAGGRRTEPGRLRAPPESLALLPGAVLDLSTGVGAAGSPPEALPPGWVVIPPGSLLLKPAVVN", "length": 511 }, "evidence": [ { "id": "E1BKE4", "url": "https://omabrowser.org/oma/group/E1BKE4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZIA9-1", "protein_name": "Zinc finger protein GLIS2", "gene_name": "Glis2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHSLDEPLDLKLSITKLRAAREKRERTLGVPRHHALHRELGLVDDSPTPGSPGSPPPGFLLNPKFPEKLDGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPLPTAVDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPELPLAKQLVCRWAKCNQLFELLQDLVDHVNDHHVKPEQDARYCCHWEGCARHGRGFNASRYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPTPDSGSYVSGAQIIIPNPAALFGGPSLPGLPLPLAPGPLDLSALACGNGGGGGGGMGPGLPGSVLPLNLAKNPLLPSPFGAGGLGLPVVSLLGGSAGSKAEGEKGRGSVPARVLGLEDHKTSLERTERSRSRPSPDGLPLLPGTVLDLSTGNSAASSPEALTPGWVVIPPGSVLLKPAVVN", "length": 522 }, "evidence": [ { "id": "E1BKE4", "url": "https://omabrowser.org/oma/group/E1BKE4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VDL9-1", "protein_name": "Zinc finger protein GLIS2", "gene_name": "Glis2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHSLDEPLDLKLSITKLRAAREKRERTLGVVRHHALHRELGLVDDSPAPGSPGSPPPGFLLNPKFPEKVDGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPECQGNGDLPPLPTAVDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLPPPKDKCLSPELPLAKQLVCRWAKCNQLFELLQDLVDHVNDHHVKPEQDARYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPTPDSGSYVSGAQIIIPNPAALFGGPSLPGLPLPLPPGPLDLSALACGNGGGGGGGIGPGLPGSVLPLNLAKNPLLPSPFGAGGLGLPVVSLLGGSAGSKAEGEKGRGSVPARVLGLEDHKTPLERTERSRSRPSPDGLPLLPGTVLDLSTGNSAASSPEVLTPGWVVIPPGSVLLKPAVVN", "length": 521 }, "evidence": [ { "id": "E1BKE4", "url": "https://omabrowser.org/oma/group/E1BKE4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZE0-1", "protein_name": "Zinc finger protein GLIS2", "gene_name": "GLIS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSPGSPPSGFLLNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGGPYVSGAQIIIPNPAALFGGPGLPGLPLPLAPGPLDLSALACGNGGGSGGGGGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN", "length": 524 }, "evidence": [ { "id": "E1BKE4", "url": "https://omabrowser.org/oma/group/E1BKE4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "non-motile cilium", "id": "GO:0097730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097730", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BKE4", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKE4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 524, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKE4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKE4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKE4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 202, "end_pos": 234, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 48 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 254, "end_pos": 256 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"length": 1290, "header": "tr|E1BKH5-1|E1BKH5_BOVIN Isoform 1 of Histone-lysine N-methyltransferase SETDB1 OS=Bos taurus OX=9913 GN=SETDB1 PE=4 SV=3 CANONICAL=E1BKH5-1" }, "isoforms": [ { "isoform_ac": "E1BKH5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKH5/entry#E1BKH5-1", "sequence": { "sequence": 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"length": 1290, "header": "tr|E1BKH5-1|E1BKH5_BOVIN Isoform 1 of Histone-lysine N-methyltransferase SETDB1 OS=Bos taurus OX=9913 GN=SETDB1 PE=4 SV=3 CANONICAL=E1BKH5-1" }, "locus": { "chromosome": "3", "start_pos": 19833266, "end_pos": 19802645, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000107.6", "url": "https://www.ensembl.org/id/ENSBTAT00000000107.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000107.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000107.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 455, "start_aa": "Thr", "end_pos": 455, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr455", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Histone-lysine N-methyltransferase SETDB1 is required for development of the bovine blastocyst.", "journal": "Theriogenology", "date": "2015-11", "authors": "Golding Michael C, Snyder Matthew, Williamson Gayle L, Veazey Kylee J, Peoples Michael, Pryor Jane H, Westhusin Mark E, Long Charles R", "evidence": [ { "database": "RefSeq", "id": "NP_001178317", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178317" } ], "reference": [ { "type": "PubMed", "id": "26279314", "url": "https://glygen.org/publication/PubMed/26279314" } ] } ], "pathway": [ { "id": "bta:100138100", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138100", "resource": "KEGG Pathway" }, { "id": "R-BTA-3214841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214841", "resource": "Reactome", "description": "PKMTs methylate histone lysines" }, { "id": "R-BTA-9843940", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9843940", "resource": "Reactome", "description": "Regulation of endogenous retroelements by KRAB-ZFP proteins" }, { "id": "R-BTA-9843970", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9843970", "resource": "Reactome", "description": "Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A081-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "Setdb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLGVFKSQLSTGKQNSGESMSSLPGCMSLAAAPAAADSAEIAELQQAVVEELGISMEELRQFIDEELEKMDCIQQRKKQLAELETWVLQKESEVAYVDRLFDDASREVTNCESLVKDFYSKLGLQYHDSSSDDEASQPTEIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLFVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQDLTSTGIQFKPMEPLQPIVPPAPLPMLPLSPQAGDSESLESQLAQSRKQVAKKSTSFRPGSVSSGHSSPTSPTLSENVPPGKIGMNQTYRSPSASVTSTPAPAAPSGPPAPPGPLAPPGPPAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRIRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLYLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTVQATACTPGGQINPSSGYQHKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPSSSDSSGVDMKDQEDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKESELSEVTSKDSRAPDRGPPHVPITPSGSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTSEGGDGRAGGGRGEAERASTSGLSFKDEGDSKQSKKEDPEDRNKMSVVTEGSQNHGHNPPMKSEGLRRPASKISMLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTTGQTSATAVDSDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL", "length": 1322 }, "evidence": [ { "id": "E1BKH5", "url": "https://omabrowser.org/oma/group/E1BKH5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O88974-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "Setdb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLPGCMSLAAAPAAADSAEIAELQQAVVEELGISMEELRQYIDEELEKMDCIQQRKKQLAELETWVLQKESEVAYVDRLFDDASREVTNCESLVKDFYSKLGLQYHDSSSEDEASRPTEIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLFVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQDLTGTGIQFKPMEPLQPIAPPAPLPIPPLSPQAADTDLESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSSTLSENVSAGKLGINQTYRSPLASVTSTPASAAPPVPPVPPGPPTPPGPPAPPGPLAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRIRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQVNPNSGYQYKRLEECLPTGVYECNKRCNCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPTSSDSSGVDMKDQEDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENELSEMTSKDSRPPDLGPPHVPIPSSVSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTSEGGDGRAGGGRGEAERASTSGLSFKDEGDNKQPKKEDPENRNKMPVVTEGSQNHGHNPPMKSEGLRRPASKMSVLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTAGHTSATAVDSDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL", "length": 1307 }, "evidence": [ { "id": "E1BKH5", "url": "https://omabrowser.org/oma/group/E1BKH5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q08BR4-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1-B", "gene_name": "setdb1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEMELEPELEEELGVSLDELRKWIEEQVDSSEAVQKRKADLEQLQEWVEQREKEVADIDALCSNASESVVQCEALVKEVYSNMGLVYRESSSDDEGGKANPSEVIEIDDDDDDDVIAVGCLVPPKKSLTQAKDPALKEASAALQRTSQQVQNLAQTVNRTAQSGVTTPVKTGGPPGQGPLAVPAVFMSSAPRNTPTQPNPNIKQDSIKINMTLLGKKRTKTWHRGTLVAIKQVGNNLKYKVRFENKGKSLLSGNHVAFEYHPTLERLFVGARVVARYKDGNQVWLYAGVVAEMPNSKNRMRFLIFFDDGYASYVGLPELYPICRPLKKTWEDIEDASCRDFIEEYITSYPNRPMVLLKPGQIIKTEWEGTWWKSRVEEVDGSLVKMLFLDDKRSEWIYRGSTRLEPMFNLKMNTANSQEKKMAGQQRQRPNMGALRTKGPVVQYTSDNSAAASTGGGAATPGTPTRPVAPQPAGPPQPSRTESPSFKSQMAKKSTGQLALQPRQGMPSDLQPKPIINALQTNTSRLFLLQSGPVHTLTPITPAPQTVQTAISTYTNERVPQEPSYQAPNDRLFYLTHNCSPECLKRIRPTRPNLHRGRNPLLTPLLYEFRRMTGRRRLNRKMSFHVIYKSPCGLSLRNMTEIQRYLFQTQCDFIFLEMFCLDPYVLVDRRFQPQRPFYFIRDITSGREDIPLSCVNEIDNTPPPSVAYSKERIPEDGVYINTSADFLVGCDCTDGCRDKSKCSCHQLTLQATGCTPGGQINPNAGYHYKRLDECLPTGIYECNKRCRCNMQMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESEAHCSDSEGSGVDMSRVKLPASSRHGKSNKMEERNSSTTGKSQDDSSEESDDEKDDDSNEDDSDSSDDTFVKDTYYTTSSVWRSYTTRRQAKGLKEESQDSKDGMSVSAGEDRKPPHMPEETGKSKVASWLTNQSSTSANQSVKVEGGIKTEKKDVMTLSDSDDVQTISSGSDDNKEREKKTQAVVKRQVAVKSTRGIALKSHSMMVKSGGGGAGGGGSGPSHGHGGGGGDNGPKNTRLFFDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGSTECRGRLLQIIKTEWEGTWW", "length": 1216 }, "evidence": [ { "id": "E1BKH5", "url": "https://omabrowser.org/oma/group/E1BKH5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQLAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPTEIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRPNMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPSALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVPPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRMEAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKTSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSGSEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL", "length": 1291 }, "evidence": [ { "id": "E1BKH5", "url": "https://omabrowser.org/oma/group/E1BKH5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" }, { "name": "histone H3K9 methyltransferase activity", "id": "GO:0046974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046974", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" }, { "name": "histone H3K9me2 methyltransferase activity", "id": "GO:0140947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140947", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" }, { "name": "DNA methylation-dependent constitutive heterochromatin formation", "id": "GO:0006346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006346", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" }, { "name": "heterochromatin organization", "id": "GO:0070828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070828", "evidence": [ { "database": "UniProtKB", "id": "E1BKH5", "url": "https://www.uniprot.org/uniprotkb/E1BKH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1149, "end_pos": 1151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1222, "end_pos": 1224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 525, "end_pos": 527, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60280", "name": "", "equation": "L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BGA4-1", "E1BKH5-1" ], "evidence": [ { "id": "60280", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60280" } ] }, { "id": "60288", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MXG0-1", "E1BKH5-1", "A0AAA9RUH2-1", "Q2NL30-1", "Q32PH7-1" ], "evidence": [ { "id": "60288", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60288" } ] }, { "id": "64444", "name": "", "equation": "L-lysyl(9)-[histone H3] + 2 S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2 S-adenosyl-L-homocysteine + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKH5-1" ], "evidence": [ { "id": "64444", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64444" } ] }, { "id": "R-BTA-4827382", "name": "SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MXG0-1", "A0AAA9RUH2-1", "F1N6Y5-1", "E1BKH5-1" ], "evidence": [ { "id": "R-BTA-4827382", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4827382" } ] }, { "id": "R-BTA-5159250", "name": "ATF7IP binds SETDB1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKH5-1" ], "evidence": [ { "id": "R-BTA-5159250", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5159250" } ] }, { "id": "R-BTA-9842833", "name": "SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BJG5-1", "E1BKH5-1" ], "evidence": [ { "id": "R-BTA-9842833", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9842833" } ] }, { "id": "R-BTA-9842839", "name": "ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BJG5-1", "E1BKH5-1" ], "evidence": [ { "id": "R-BTA-9842839", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9842839" } ] }, { "id": "R-BTA-9844006", "name": "SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKH5-1" ], "evidence": [ { "id": "R-BTA-9844006", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9844006" } ] }, { "id": "R-BTA-9844057", "name": "SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKH5-1" ], "evidence": [ { "id": "R-BTA-9844057", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9844057" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9RUH2", "gene_name": "SUV39H1", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0AAA9RUH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUH2" } ] } ] }, { "uniprot_ac": "E1BGA4", "gene_name": "ASH1L", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] }, { "ec_number": "2.1.1.367", "activity": "L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] }, { "ec_number": "2.1.1.367", "activity": "", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] } ] }, { "uniprot_ac": "E1BJG5", "gene_name": "TRIM28", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BJG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJG5" } ] }, { 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{ "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKJ2", "url": "https://www.uniprot.org/uniprotkb/E1BKJ2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPC2", "url": "https://www.uniprot.org/uniprotkb/E1BKJ2", "locus": { "chromosome": "25", "start_pos": 36240535, "end_pos": 36234604, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008869", "url": "https://www.ensembl.org/id/ENSBTAG00000008869" } ] } } ], "crossref": [ { "id": "E1BKJ2", "url": "https://alphafold.ebi.ac.uk/entry/E1BKJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008869", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008869", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618005", "url": "https://www.ncbi.nlm.nih.gov/gene/618005", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001863", "url": 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"header": "tr|E1BKJ2-1|E1BKJ2_BOVIN Isoform 1 of Glypican 2 OS=Bos taurus OX=9913 GN=GPC2 PE=3 SV=3 CANONICAL=E1BKJ2-1" }, "isoforms": [ { "isoform_ac": "E1BKJ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BKJ2/entry#E1BKJ2-1", "sequence": { "sequence": "MYALRSLLLLLLPLCPGPGPGPGIEAKVTRSCTETRQILGARGYSLSVLPPALISGEHLRICPQEYTCCSSEIEQRLTWETEATFRGLVEENGSFLVHTLAARHRKFDEVFREMLSSAEHSLSMLFHRSFGRLYTQHTPLFSGLFSRLRDYYERSGEGLDDALVDFWAQLLEKMFPLLHPQYIFSPDYLFCLTRLASSADDSLKPFGDSPRRLRLQITRALVAARAFVQGLETGRNVVSETLKMPLSEGCKRAVMRLTGCPLCRGVPSLPPCRGFCLNVAYGCIGSQGLDPDWGPYLDGLLFLADKIQGPFSFELAAQSIGVKISEGLMHLQENSVGVSAQVFQECGSPQPARARARRAPAPREEVGRFWSAAAAAEEERPTTAAGASLPRLVWELRERLGRVRGIWAGLPQTVCGDPRVAADLSQEAAPCWTGAGPGRYLSPVVGFQAGKLDNPELDAEASSPDLQTRRRRLQLRATTTRMKAAALGRDLELEDWEDASGSGEGQHYADDWMAGAAAVAPPARAPRPPRREGAGGKGGGVIIRHSQDRSRTGGTSVGFHTQPLLILFLLALALLGPR", "length": 578, "header": "tr|E1BKJ2-1|E1BKJ2_BOVIN Isoform 1 of Glypican 2 OS=Bos taurus OX=9913 GN=GPC2 PE=3 SV=3 CANONICAL=E1BKJ2-1" }, "locus": { "chromosome": "25", "start_pos": 36240450, "end_pos": 36234803, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011679.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011679.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011679.6", "url": "https://www.ensembl.org/id/ENSBTAP00000011679.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1971475", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1971475", "resource": "Reactome", "description": "Glycosaminoglycan-protein linkage region biosynthesis" }, { "id": "R-BTA-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" }, { "id": "R-BTA-2024096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2024096", "resource": "Reactome", "description": "HS-GAG degradation" }, { "id": "R-BTA-975634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975634", "resource": "Reactome", "description": "Retinoid metabolism and transport" }, { "id": "R-BTA-9769735", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769735", "resource": "Reactome", "description": "Initiation of coagulation cascade" }, { "id": "R-BTA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RNM8-1", "protein_name": "Glypican 2", "gene_name": "GPC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYALRSLLLLLLPLCPGPGPGPGIEAKVTRSCIETRQILGARGYSLSLLPPALISGEHLRICPQEYTCCSSEIEQRLTWETETTFRGLVEENGSFLVHTLAARHRKFDDVFREMLSSAEHSLSLLFHRSFGRLYAQHTLLFSGLFSRLRDYYERSGAGLDDALVDFWAQLLEKMFPLLHPQYTFSPDYLFCLTRLASSADDSLKPFGDSPRRLRLQITRALVAARAFVQGLETGRDVVSETLKMPMSEGCRRAVMRLTGCPLCRGVPSLPPCRGFCLNVAHGCIGSQGLDPDWGPYLDGLLLLAEKIQGPFSFELAAQSIGAKISEGLMHLQENSVGVSAQVFQECGSPQPTPARARRAPAPREEVSRLWSAAAAEERPATAAGSSLPQLVWELRERLSRVRGFWAGLPLAVCGDPRMAADLSQEASPCWTGAGQGRYLSPVVGGSQAQHLDNPELDAEASSPDLQTRRRRLKLRAATSRMKAAAQGRDLEQEDWEDASGSGEGQHYADDWMAGAAAAAPPGRPLRPPRRDSAGGKGGNVLIRHNQDRNRTGGTSIGFHAQPLLILFLSALALLGPR", "length": 577 }, "evidence": [ { "id": "E1BKJ2", "url": "https://omabrowser.org/oma/group/E1BKJ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P51653-1", "protein_name": "Glypican-2", "gene_name": "Gpc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAVRPLLLLLLPLCPGPGPGHGSEAKVVRSCAETRQVLGARGYSLNLIPPSLISGEHLQICPQEYTCCSSETEQKLIRDAEVTFRGLVEDSGSFLIHTLAARHRKFNEFFREMLSISQHSLAQLFSHSYGRLYSQHAVIFNSLFSGLRDYYEKSGEGLDDTLADFWAQLLERAFPLLHPQYSFPPDFLLCLTRLTSTADGSLQPFGDSPRRLRLQITRALVAARALVQGLETGRNVVSEALKVPMLEGCRQALMRLIGCPLCRGVPSLMPCRGFCLNVAHGCLSSRGLEPEWGGYLDGLLLLAEKLQGPFSFELAAESIGVKISEGLMHLQENSVKVSAKVFQECGTPHPVQSRNRRAPAPREETSRSWRSSAEEERPTTAAGTNLHRLVWELRERLSRVRGFWAGLPVTVCGDSRMAADLSQEAAPCWTGVGRGRYMSPVVVGSLNEQLHNPELDTSSPDVPTRRRRLHLRAATARMKAAALGQDLDMHDADEDASGSGGGQQYADDWKAGAAPVVPPARPPRPPRPPRRDGLGVRGGSGSARYNQGRSRNLGSSVGLHAPRVFILLPSALTLLGLR", "length": 579 }, "evidence": [ { "id": "E1BKJ2", "url": "https://omabrowser.org/oma/group/E1BKJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BKV1-1", "protein_name": "Glypican-2", "gene_name": "Gpc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKM2-1", "uniprot_ac": "E1BKM2", "uniprot_id": "E1BKM2_BOVIN", "mass": { "chemical_mass": 51836.0, "monoisotopic_mass": 51836.0 }, "refseq": { "ac": "NP_001193327", "name": "protein ABHD15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193327" }, "gene_names": [ { "name": "ABHD15", "type": "recommended", "evidence": [ { "id": "E1BKM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM2" } ] }, { "name": "ABHD15", "type": "synonym", "evidence": [ { "id": "NP_001193327", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193327" } ] } ], "protein_names": [ { "name": "Protein ABHD15", "type": "recommended", "evidence": [ { "id": "E1BKM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM2/entry#names_and_taxonomy" } ] }, { "name": "Alpha/beta hydrolase domain-containing protein 15", "type": "synonym", "evidence": [ { "id": "E1BKM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM2/entry#names_and_taxonomy" } ] }, { "name": "protein ABHD15", "type": "synonym", "evidence": [ { "id": "NP_001193327", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193327" } ] } ], "function": [ { "annotation": "May regulate adipocyte lipolysis and liver lipid accumulation.", "evidence": [ { "database": "UniProtKB", "id": "E1BKM2", "url": "https://www.uniprot.org/uniprotkb/E1BKM2#function" }, { "database": "UniProtKB", "id": "ARBA00053358", "url": "https://www.uniprot.org/uniprotkb/ARBA00053358#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKM2", "url": "https://www.uniprot.org/uniprotkb/E1BKM2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ABHD15", "url": 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"bta:528755", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528755", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AWSHEAT", "url": "https://omabrowser.org/oma/group/AWSHEAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKM2", "url": "https://www.orthodb.org/?gene=E1BKM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10794", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10794", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10794:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10794:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001193327", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193327", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BKM2", "url": "https://www.uniprot.org/uniprotkb/E1BKM2", "database": "UniProtKB", 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"MPPWGAALALLLAALALLCLLVLRLRRPGRRAVGARTLPGARGEDHGEEVDGGGPAGQFSDGREPLPGGCSLICKPSALAQCLLRALRRSAALEPGPRPWLSGPHLQTLCHFVLPVGPGSELAREYLQLADDGLVALDWVVGPGARGRRATNAGGLPAVLLVIPNAWGRLTRNVLGLCLLALERGYYPVIFHRRGHHGCPLVSPRLQPFGDPSDLKEAITYIRFRHPAAPLFAVSEGSGSALLLSYLGECGSSSYMTGAACISPVLRCREWFEAGLPWPYERGFLLHQKIALSRYATALEDTVDTGKLFRSRSLREFEETLFCHTKSFPISWDTYWDHNDPLRDVDEAAVPVLCICSADDPVCGPPNHFLPTELFHSNPYFFLLLSRHGGHCGFLRQEPLPAWSHEVTLEYFRALTDFFRTEERMKGLSRRRASFLAGRRRWGTLPKREVSPSSSLEEIFSWKRSYTR", "length": 468, "header": "tr|E1BKM2-1|E1BKM2_BOVIN Isoform 1 of Protein ABHD15 OS=Bos taurus OX=9913 GN=ABHD15 PE=3 SV=1 CANONICAL=E1BKM2-1" }, "locus": { "chromosome": "19", "start_pos": 20821582, "end_pos": 20816666, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035254.4", "url": "https://www.ensembl.org/id/ENSBTAT00000035254.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000035132.2", "url": "https://www.ensembl.org/id/ENSBTAP00000035132.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:528755", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528755", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z8B6-1", "protein_name": "Protein ABHD15", "gene_name": "Abhd15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPWPAALALLLAALALLLLRPWKRAVGARTSVRDHEEQEVVSGGPADHFSDRREPLPGGCSLICKPSALAQCLLRALRRSAALEPSPRSWLSGPHLQTFCHFILPVGPDPELAREYLQLADDGLVALDWVIGPCARGRRVTNPGSLPPVLLVIPNAWGRLTRNVLGLCLLALEHGYYPVIFHRRGHHGCPLVSPRLQPFGDPSDLKEAVTYIRFRHPAAPLFAVSEGSGSALLLSYLGECGSSSYVTGAACISPVLRCREWFEAGLPWPYERGFLLYQKIALSRYASALEDTVDTGKLFKSSSLREFEETLFCHTKSLPISWDTYWDLNDPLRDVDEAAVPVLCICSADDPVCGPPDRTLPAELFHTNPYFFLLLSSHGGHCGFLRPEPLPAWSHEIILESFRALTEFFRMEERMKGLSRRRTSFLGGRRRWGGLQKREVSPSSNLEEIFDWKRSYTR", "length": 459 }, "evidence": [ { "id": "E1BKM2", "url": "https://omabrowser.org/oma/group/E1BKM2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5F2F2-1", "protein_name": "Protein ABHD15", "gene_name": "Abhd15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPWAAALALLLAALALLLLRPWKRAVGARTSVRDHEEQEVASGGPADQFSDRREALPGGCSLICKPSALAQCLLRALRRSAALEPSPRSWLSGPHLQTFCHFILPVGPGPELAREYLQLADDGLVALDWVIGPCARGRRVTNPGSLPPVLLVIPNAWGRLTRNVLGLCLLALERGYYPVIFHRRGHHGCPLVSPRLQPFGDPSDLKEAVTYIRFRHPAAPLFAVSEGSGSALLLSYLGECGSSSYVTGAACISPVLRCREWFEAGLPWPYERGFLLHQKISLSRYASALEDTVDTGKLFRSGSLREFEETLFCHTKSCPISWDTYWDLNDPLRDVDEAAVPVLCICSADDPVCGPPEHTLPAELFHSNPYFFLLLSHHGGHCGFLRPEPLPAWSHEVILESFRALTEFFRMEERMKGLSRRRTSFLGGRRRWGGLQKREVSPSSNLEEIFNWKRSYTR", "length": 459 }, "evidence": [ { "id": "E1BKM2", "url": "https://omabrowser.org/oma/group/E1BKM2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UXT9-1", "protein_name": "Protein ABHD15", "gene_name": "ABHD15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPWGAALALILAVLALLGLLGPRLRGPWGRAVGERTLPGAQDRDDGEEADGGGPADQFSDGREPLPGGCSLVCKPSALAQCLLRALRRSEALEAGPRSWFSGPHLQTLCHFVLPVAPGPELAREYLQLADDGLVALDWVVGPCVRGRRITSAGGLPAVLLVIPNAWGRLTRNVLGLCLLALERGYYPVIFHRRGHHGCPLVSPRLQPFGDPSDLKEAVTYIRFRHPAAPLFAVSEGSGSALLLSYLGECGSSSYVTGAACISPVLRCREWFEAGLPWPYERGFLLHQKIALSRYATALEDTVDTSRLFRSRSLREFEEALFCHTKSFPISWDTYWDRNDPLRDVDEAAVPVLCICSADDPVCGPPDHTLTTELFHSNPYFFLLLSRHGGHCGFLRQEPLPAWSHEVILESFRALTEFFRTEERIKGLSRHRASFLGGRRRGGALQRREVSSSSNLEEIFNWKRSYTR", "length": 468 }, "evidence": [ { "id": "E1BKM2", "url": "https://omabrowser.org/oma/group/E1BKM2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BKM2", "url": "https://www.uniprot.org/uniprotkb/E1BKM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "E1BKM2", "url": "https://www.uniprot.org/uniprotkb/E1BKM2" } ], "pmid": "" }, { "name": "adipose tissue development", "id": "GO:0060612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060612", "evidence": [ { "database": "UniProtKB", "id": "E1BKM2", "url": "https://www.uniprot.org/uniprotkb/E1BKM2" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "E1BKM2", "url": "https://www.uniprot.org/uniprotkb/E1BKM2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "E1BKM2", "url": "https://www.uniprot.org/uniprotkb/E1BKM2" } ], "pmid": "" }, { "name": "short-chain carboxylesterase activity", "id": "GO:0034338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034338", "evidence": [ { "database": "UniProtKB", "id": "E1BKM2", "url": "https://www.uniprot.org/uniprotkb/E1BKM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKM2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 468, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKM2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKM2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"ENSBTAG00000017418", "url": "https://www.ensembl.org/id/ENSBTAG00000017418" } ] } } ], "crossref": [ { "id": "E1BKN1", "url": "https://alphafold.ebi.ac.uk/entry/E1BKN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017418", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017418", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510240", "url": "https://www.ncbi.nlm.nih.gov/gene/510240", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BKN1", "url": "https://www.orthodb.org/?gene=E1BKN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13026:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13026:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05997", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05997", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002685189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685189", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKN1-1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZM6", "url": "https://www.uniprot.org/uniprotkb/G3MZM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZM6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPAMQPAEIQFAQRLASHEKGIRDRAVKKLRQYISVKTQKETGGFSQEELLKIWKGLFYCMWVQDEPLLQEELANTISQLIHVVNNSEAQHLFIQTFWQTVNREWPGIEGLRLDKYHMLIRLVLRQSFEVLKRNGWEESRIKLFLNVLMKAVLHPESRSPNGVKLLFVNIYLDELSKVGGKELLADQNLKFIDPFCKIAAKTRDQTLVQTIARGVFEVIVDQSPFVPEETAKEQKTQMGGGGLSEEEASGNEMTWRKAARKKKAALGKCHPGKEEGSQQGGQDGSGSVEDTGPLLQFDYKAVADRLLEMTNRKNVPPFNRKRLSELIKKFRGLSAARSLSRLSFAEDTTADEDDQTHSQGTHRKKGNKLLEKTDMAGEKGTTFSPAKEEESKGGIPKKKRKKKKKKQLQAECTGPSGEATRPEQNGSQEPEASPKRAPEAGGADLGILAMPCTQEQSSLERPSLHNRRKRPRKRSPRIQVEGLEPTASPLEGVAPQAAPASGAPVLKRRRELGALLVNGSGPPVLAWPLPQREGPPANPADRRDCPSSLPLGGKLKKKSGGPSGLDLYDSCAQKAAILKKRKKMKEMSNLVEPRGLKLVPALGSGGAHGPLKKKLRTEKDFMAFDTASSPKPLFFRKARGSTAPSLGPTLQPHTTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSRVAFNPEQRPLHGVLKTPTSSPASTPLGPKKPLTVTPKRRPTAMDFF", "length": 737, "header": "tr|E1BKN1-1|E1BKN1_BOVIN Isoform 1 of Ribosomal RNA processing 1B OS=Bos taurus OX=9913 GN=RRP1B PE=3 SV=5 CANONICAL=E1BKN1-1" }, "isoforms": [ { "isoform_ac": "E1BKN1-1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1/entry#E1BKN1-1", "sequence": { "sequence": "MAPAMQPAEIQFAQRLASHEKGIRDRAVKKLRQYISVKTQKETGGFSQEELLKIWKGLFYCMWVQDEPLLQEELANTISQLIHVVNNSEAQHLFIQTFWQTVNREWPGIEGLRLDKYHMLIRLVLRQSFEVLKRNGWEESRIKLFLNVLMKAVLHPESRSPNGVKLLFVNIYLDELSKVGGKELLADQNLKFIDPFCKIAAKTRDQTLVQTIARGVFEVIVDQSPFVPEETAKEQKTQMGGGGLSEEEASGNEMTWRKAARKKKAALGKCHPGKEEGSQQGGQDGSGSVEDTGPLLQFDYKAVADRLLEMTNRKNVPPFNRKRLSELIKKFRGLSAARSLSRLSFAEDTTADEDDQTHSQGTHRKKGNKLLEKTDMAGEKGTTFSPAKEEESKGGIPKKKRKKKKKKQLQAECTGPSGEATRPEQNGSQEPEASPKRAPEAGGADLGILAMPCTQEQSSLERPSLHNRRKRPRKRSPRIQVEGLEPTASPLEGVAPQAAPASGAPVLKRRRELGALLVNGSGPPVLAWPLPQREGPPANPADRRDCPSSLPLGGKLKKKSGGPSGLDLYDSCAQKAAILKKRKKMKEMSNLVEPRGLKLVPALGSGGAHGPLKKKLRTEKDFMAFDTASSPKPLFFRKARGSTAPSLGPTLQPHTTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSRVAFNPEQRPLHGVLKTPTSSPASTPLGPKKPLTVTPKRRPTAMDFF", "length": 737, "header": "tr|E1BKN1-1|E1BKN1_BOVIN Isoform 1 of Ribosomal RNA processing 1B OS=Bos taurus OX=9913 GN=RRP1B PE=3 SV=5 CANONICAL=E1BKN1-1" }, "locus": { "chromosome": "1", "start_pos": 143753694, "end_pos": 143729215, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023157.8", "url": "https://www.ensembl.org/id/ENSBTAT00000023157.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023157.8", "url": "https://www.ensembl.org/id/ENSBTAP00000023157.8" } ] } }, { "isoform_ac": "G3MZM6-1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1/entry#G3MZM6-1", "sequence": { "sequence": "MAPHSSTVAWKIPWTEEPGGFSQEELLKIWKGLFYCMWVQDEPLLQEELANTISQLIHVVNNSEAQHLFIQTFWQTVNREWPGIEGLRLDKYHMLIRLVLRQSFEVLKRNGWEESRIKLFLNVLMKAVLHPESRSPNGVKLLFVNIYLDELSKVGGKELLADQNLKFIDPFCKIAAKTRDQTLVQTIARGVFEVIVDQSPFVPEETAKEQKTQMGGGGLSEEEASGNEMTWRKAARKKKAALGKCHPGKEEGSQQGGQDGSGSVEDTGPLLQFDYKAVADRLLEMTNRKNVPPFNRKRLSELIKKFRGLSAARSLSRLSFAEDTTADEDDQTHSQGTHRKKGNKLLEKTDMAGEKGTTFSPAKEEESKGGIPKKKRKKKKKKQLQAECTGPSGEATRPEQNGSQEPEASPKRAPEAGGADLGILAMPCTQEQSSLERPSLHNRRKRPRKRSPRIQVEGLEPTASPLEGVAPQAAPASGAPVLKRRRELGALLVNGSGPPVLAWPLPQREGPPANPADRRDCPSSLPLGGKLKKKSGGPSGLDLYDSCAQKAAILKKRKKMKEMSNLVEPRGLKLVPALGSGGAHGPLKKKLRTEKDFMAFDTASSPKPLFFRKARGSTAPSLGPTLQPHTTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSRVAFNPEQRPLHGVLKTPTSSPASTPLGPKKPLTVTPKRRPTAMDFF", "length": 712, "header": "tr|G3MZM6-1|E1BKN1_BOVIN Computationally mapped isoform of Ribosomal RNA processing 1B OS=Bos taurus OX=9913 GN=RRP1B PE=3 SV=3 CANONICAL=E1BKN1-1" }, "locus": { "chromosome": "1", "start_pos": 143753694, "end_pos": 143732989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063907.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063907.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055027.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055027.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" }, { "name": "granular component", "id": "GO:0001652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001652", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" }, { "name": "host-mediated activation of viral transcription", "id": "GO:0043923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043923", "evidence": [ { "database": "UniProtKB", "id": "E1BKN1", "url": "https://www.uniprot.org/uniprotkb/E1BKN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 670, "end_pos": 672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKN1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 737, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKN1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKN1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 426, "end_pos": 428 }, { "start_pos": 519, "end_pos": 521 }, { "start_pos": 670, "end_pos": 672 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKS5-1", "uniprot_ac": "E1BKS5", "uniprot_id": "E1BKS5_BOVIN", "mass": { "chemical_mass": 86478.0, "monoisotopic_mass": 86478.0 }, "refseq": { "ac": "NP_001179800", "name": "phosphate-regulating neutral endopeptidase PHEX", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179800" }, "gene_names": [ { "name": "PHEX", "type": "recommended", "evidence": [ { "id": "E1BKS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKS5" } ] }, { "name": "PHEX", "type": "synonym", "evidence": [ { "id": "NP_001179800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179800" } ] } ], "protein_names": [ { "name": "Phosphate regulating endopeptidase X-linked", "type": "synonym", "evidence": [ { "id": "E1BKS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKS5/entry#names_and_taxonomy" } ] }, { "name": "phosphate regulating endopeptidase homolog X-linked", "type": "synonym", "evidence": [ { "id": "NP_001179800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179800" } ] }, { "name": "phosphate-regulating neutral endopeptidase PHEX", "type": "synonym", "evidence": [ { "id": "NP_001179800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179800" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKS5", "url": "https://www.uniprot.org/uniprotkb/E1BKS5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PHEX", "url": "https://www.uniprot.org/uniprotkb/E1BKS5", "locus": { "chromosome": "X", "start_pos": 121079646, "end_pos": 121291280, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000419", "url": "https://www.ensembl.org/id/ENSBTAG00000000419" } ] } } ], "crossref": [ { "id": "E1BKS5", "url": "https://alphafold.ebi.ac.uk/entry/E1BKS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000419", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000419", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08662", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08662", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "536029", "url": "https://www.ncbi.nlm.nih.gov/gene/536029", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536029", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536029", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QAKPEYC", "url": "https://omabrowser.org/oma/group/QAKPEYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKS5", "url": "https://www.orthodb.org/?gene=E1BKS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11733", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11733", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11733:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11733:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05649", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05649", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179800", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179800", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BKS5", "url": "https://www.uniprot.org/uniprotkb/E1BKS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKS5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAETGSSMEIGKTANRGTRIALAVFVGGTLVLGIVLFLVSQGFLSLHAKPEYCLKPECIEAAASILSKVNLSVDPCDNFFRFACDGWIHSNPIPEDMPSYGIYPWLRRNVDLKLKALLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLESNIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSSDDKMSNEHILKLDQAALSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAMYNKMNISQLSAMIPQFDWLSYIKKVIDVRLYPELKDIGPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESTLPYVVGKMFVNVHFQEDKKEMMEELIEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTHINEDLKAIKFSESDYFGNVLQTRKYLAQTDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSMDSEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLRQAFRAYRKWINDKRQGVEEPLLPGIEFTNNQLFFMSYAHVRCNSYRPEAAREQIQAGAHSPPQFRVNGAVSNFEEFQKAFNCPSNSTMNRGAESCRLW", "length": 749, "header": "tr|E1BKS5-1|E1BKS5_BOVIN Isoform 1 of Phosphate regulating endopeptidase X-linked OS=Bos taurus OX=9913 GN=PHEX PE=4 SV=3 CANONICAL=E1BKS5-1" }, "isoforms": [ { "isoform_ac": "E1BKS5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKS5/entry#E1BKS5-1", "sequence": { "sequence": "MEAETGSSMEIGKTANRGTRIALAVFVGGTLVLGIVLFLVSQGFLSLHAKPEYCLKPECIEAAASILSKVNLSVDPCDNFFRFACDGWIHSNPIPEDMPSYGIYPWLRRNVDLKLKALLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLESNIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSSDDKMSNEHILKLDQAALSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAMYNKMNISQLSAMIPQFDWLSYIKKVIDVRLYPELKDIGPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESTLPYVVGKMFVNVHFQEDKKEMMEELIEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTHINEDLKAIKFSESDYFGNVLQTRKYLAQTDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSMDSEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLRQAFRAYRKWINDKRQGVEEPLLPGIEFTNNQLFFMSYAHVRCNSYRPEAAREQIQAGAHSPPQFRVNGAVSNFEEFQKAFNCPSNSTMNRGAESCRLW", "length": 749, "header": "tr|E1BKS5-1|E1BKS5_BOVIN Isoform 1 of Phosphate regulating endopeptidase X-linked OS=Bos taurus OX=9913 GN=PHEX PE=4 SV=3 CANONICAL=E1BKS5-1" }, "locus": { "chromosome": "X", "start_pos": 121290741, "end_pos": 121080650, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000540.6", "url": "https://www.ensembl.org/id/ENSBTAT00000000540.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000540.5", "url": "https://www.ensembl.org/id/ENSBTAP00000000540.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:536029", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536029", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1R6K1-1", "protein_name": "Phosphate-regulating neutral endopeptidase PHEX isoform 1", "gene_name": "phex", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEMERLGRGGTKASAGPNTLLKAALAVCVCVCIALLIAVITVSQKASNEDLCLGPHCVEAAGSILSKMDQSVDPCDDFYQYACGGWLRENPIPEDSSSYGIYPWLRQNVDLKLKELLEQPVRSGDIEAVKKAKVLYASCMNESALEIEDANPLLKNLKQKEFRWPVLGDALGSSSRWVESQFNLLETLAQIRSQHSKSVLIRLFVAPDDKNSNQYIIKLDQASLSLSSREDYITNTTEAQMYREALLRLMVDVSVMLGASEQAAEAQMKSVLDFEMKLAQIVIPYENRTSENMYNKYSLSKLQRTVPDFNWLGFVRAVIDTELYPDLKISSSEQVIVRAPQYFKDLFKLINATDTRTVANYVIWRSVFSRITTLSRRFLYRYLDFARVTTGTTSLTPRWDKCVNYVENTLIYAAGRLFVDKHFQEDKKHMMEELINGIRWAFIDILEKENEWMDEETKRKAIDKAHAVLPKVGYPDFILNDTYINEDIKRLAFTMTDYFGNVMQTLKFIAQSDIGWLRKTVPRTEWFTNPTTVNAFYSSSTNQIRFPAGELQKPFFWGLNYPRSLSYGAIGVIVGHELTHGFDNNGRKYDKDGNLDQWWSNSSINRFTEKTQCMIDQYNSYYWKEAGLNVKGKRTLAENIADNGGIRESFRAYRRWVEKERGGVEEPLLPGVGLTHNQLFFLSYAHVRCNAYRPEAARDQIQSGAHSPPKYRVIGAMSNFEEFRKAFNCPETSIMNRGAESCRVW", "length": 745 }, "evidence": [ { "id": "E1BKS5", "url": "https://omabrowser.org/oma/group/E1BKS5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SQ05-1", "protein_name": "Phosphate regulating endopeptidase X-linked", "gene_name": "PHEX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAETGSGMESGKKANRGTQIALAVFVGGTLVLGTVLFLVSQGFLSLQAKPEYCLKPECIEAAASILSKINLSVDPCDNFFRFACDGWINSNPIPEDMPSYGIYPWLRRNVDLKLKALLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLESNIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSSDDKVSNEHILKLDQAALSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAMYNKMNISQLSAMIPQFDWLGYIKKVIDVRLYPELKDLGPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESTLPYVVGKMFVNVHFQEDKKEMMEELIEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTYVNEDLKAIKFSESDYFGNVLQTRKYLAQTDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSVDSEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLRQAFRAYRKWIDDKRQGVEEPLLPGVEFSNNQLFFLSYAHVRCNSYRPEAAREQIQVGAHSPPQFRVNGAVSNFEEFQKAFNCPSNSTMNRGTDSCRLW", "length": 749 }, "evidence": [ { "id": "E1BKS5", "url": "https://omabrowser.org/oma/group/E1BKS5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3V723-1", "protein_name": "Phosphate regulating endopeptidase X-linked", "gene_name": "Phex", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAEAGSTMETGKGTNRGIRIALALFITGTLVLGTLLFLVSQGLLSFQAKQEYCLKPECIEAAAAIMSKVNLSVDPCENFFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKALLEKSVSRRRDTEAVQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLEANIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDFLDNTTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDIGPSENVVVRVPQYFKDLFRILGAERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVNVHFQEDKKEMMEELIEGVRWAFIDMLEKENEWMDAGTKRKAQEKARAVLAKVGYPEFIMNDTYVNEDLKAIKFSESDYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSVDSEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGVEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPANSTMNRGADSCRLW", "length": 749 }, "evidence": [ { "id": "E1BKS5", "url": "https://omabrowser.org/oma/group/E1BKS5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70669-1", "protein_name": "Phosphate-regulating neutral endopeptidase PHEX", "gene_name": "Phex", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAETGSTMETGKGTNRGIRIALALFIGGTLVLGTLLFLVSQGLLSFQAKQEYCLKPECIEAAAAIMSKVNLSVDPCENFFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKALLEKSVSRRRDTEAVQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLEANIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDFLDNTTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDIGPSENVVVRVPQYFKDLFRILGAERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVNVHFQEDKKEMMEELIEGVRWAFIDMLEKENEWMDAGTKRKAQEKARAVLAKVGYPEFIMNDTYVNEDLKAIKFSESDYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSVESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGVEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPRNSTMNRGADSCRLW", "length": 749 }, "evidence": [ { "id": "E1BKS5", "url": "https://omabrowser.org/oma/group/E1BKS5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P78562-1", "protein_name": "Phosphate-regulating neutral endopeptidase PHEX", "gene_name": "PHEX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAETGSSVETGKKANRGTRIALVVFVGGTLVLGTILFLVSQGLLSLQAKQEYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLESNIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSCRLW", "length": 749 }, "evidence": [ { "id": "E1BKS5", "url": "https://omabrowser.org/oma/group/E1BKS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "E1BKS5", "url": "https://www.uniprot.org/uniprotkb/E1BKS5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BKS5", "url": "https://www.uniprot.org/uniprotkb/E1BKS5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BKS5", "url": "https://www.uniprot.org/uniprotkb/E1BKS5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BKS5", "url": "https://www.uniprot.org/uniprotkb/E1BKS5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BKS5", "url": "https://www.uniprot.org/uniprotkb/E1BKS5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1BKS5", "url": "https://www.uniprot.org/uniprotkb/E1BKS5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "E1BKS5", "url": "https://www.uniprot.org/uniprotkb/E1BKS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKS5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 749, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKS5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKS5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKS5" }, { "id": "PF01431", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01431" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M13 C-terminal", "eco_id": "ECO_0000259", "start_pos": 538, "end_pos": 742, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKS5" }, { "id": "PF05649", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05649" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M13 N-terminal", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 479, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 238, "end_pos": 240 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 377, "end_pos": 379 }, { "start_pos": 484, "end_pos": 486 }, { "start_pos": 71, "end_pos": 73 }, { "start_pos": 736, "end_pos": 738 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKT4-1", "uniprot_ac": "E1BKT4", "uniprot_id": "E1BKT4_BOVIN", "mass": { "chemical_mass": 225307.0, "monoisotopic_mass": 225307.0 }, "refseq": {}, "gene_names": [ { "name": "PTPN13", "type": "recommended", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] } ], "protein_names": [ { "name": "Tyrosine-protein phosphatase non-receptor type 13", "type": "recommended", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Tyrosine phosphatase which negatively regulates FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2.", "evidence": [ { "database": "UniProtKB", "id": "E1BKT4", "url": "https://www.uniprot.org/uniprotkb/E1BKT4#function" }, { "database": "UniProtKB", "id": "ARBA00058792", "url": "https://www.uniprot.org/uniprotkb/ARBA00058792#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKT4", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PTPN13", "url": "https://www.uniprot.org/uniprotkb/E1BKT4", "locus": { "chromosome": "6", "start_pos": 101717616, "end_pos": 101531438, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014947", "url": "https://www.ensembl.org/id/ENSBTAG00000014947" } ] } } 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"length": 2038, "header": "tr|E1BKT4-1|E1BKT4_BOVIN Isoform 1 of Tyrosine-protein phosphatase non-receptor type 13 OS=Bos taurus OX=9913 GN=PTPN13 PE=3 SV=4 CANONICAL=E1BKT4-1" }, "locus": { "chromosome": "6", "start_pos": 101717613, "end_pos": 101531746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055276.4", "url": "https://www.ensembl.org/id/ENSBTAT00000055276.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051288.4", "url": "https://www.ensembl.org/id/ENSBTAP00000051288.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1156, "start_aa": "Thr", "end_pos": 1156, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1156", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1761, "start_aa": "Thr", "end_pos": 1761, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1761", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-BTA-9696264", "name": "", "url": 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"evidence": [ { "database": "UniProtKB", "id": "E1BKT4", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BKT4", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BKT4", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E1BKT4", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": 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"end_pos": 1225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1241, "end_pos": 1243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1329, "end_pos": 1331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1375, "end_pos": 1377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1416, "end_pos": 1418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1534, "end_pos": 1536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1554, "end_pos": 1556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1640, "end_pos": 1642, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1699, "end_pos": 1701, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1835, "end_pos": 1837, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1866, "end_pos": 1868, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1872, "end_pos": 1874, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2031, "end_pos": 2033, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 682, "end_pos": 684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 866, "end_pos": 868, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1ME76-1", "F1MRH9-1", "A0AAF6DLF7-1", "A0AAA9S9Q3-1", "E1BFE2-1", "E1BL76-1", "G3MXS7-1", "A0A3Q1LUB1-1", "A0AAA9THG9-1", "F1N339-1", "F6RY99-1", "A0AAF6YUC8-1", "A0AAA9RTM1-1", "A0AAA9SMJ6-1", "A0A3Q1LZA9-1", "A7MBD1-1", "A5D7P0-1", "Q58DB6-1", "A0AAA9SEK4-1", "E1BDH9-1", "F1MGK4-1", "E1BIH4-1", "A0A3Q1M6K1-1", "E1BIU8-1", "A7MBJ4-1", "A6H730-1", "A0A3Q1MFX2-1", "A0AAA9U0H6-1", "A2VDT1-1", "E1BPU9-1", "P0C591-1", "P11064-1", "Q0IID7-1", "Q2KJ36-1", "Q2T9S4-1", "E1BPA0-1", "A0AAA9TAZ9-1", "Q5BIP9-1", "A0A3Q1M5K4-1", "F1MM08-1", "E1BJR7-1", "Q17QJ3-1", "Q17QM8-1", "F1MD22-1", "F1MI99-1", "F1MP34-1", "F1MGK5-1", "F1MEZ2-1", "F1MQM7-1", "E1BEZ8-1", "A0A3Q1M0B4-1", "A0AAA9S7W5-1", "A0A3Q1N8V6-1", "A0AAA9TFV5-1", "A0A3Q1MBB1-1", "F1MTZ3-1", "A0AAF6Z8C2-1", "F1MDF1-1", "A0AAA9T5N9-1", "E1BKT4-1", "A0A3Q1MH98-1", "F1N6L3-1", "F1MW70-1", "F1MXF2-1", "A0AAA9TWD1-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-BTA-8870332", "name": "PTPN13:PLEKHA1,2 bind PI(3,4)P2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKT4-1" ], "evidence": [ { "id": "R-BTA-8870332", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8870332" } ] }, { "id": "R-BTA-9696266", "name": "RND2 binds effectors", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BJ31-1", "E1BKT4-1" ], "evidence": [ { "id": "R-BTA-9696266", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696266" } ] }, { "id": "R-BTA-9696268", "name": "RND3 binds effectors", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BJ31-1", "E1BLR9-1", "F1MYC6-1", "Q5EA61-1", "E1BKT4-1" ], "evidence": [ { "id": "R-BTA-9696268", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696268" } ] }, { "id": "R-BTA-9696271", "name": "RND1 binds effectors", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2HJ68-1", "E1BJ31-1", "E1BLR9-1", "E1BKT4-1" ], "evidence": [ { "id": "R-BTA-9696271", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696271" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LUB1", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] } ] }, { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B4", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] } ] }, { "uniprot_ac": "A0A3Q1M5K4", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] } ] }, { "uniprot_ac": "A0A3Q1M6K1", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] } ] }, { "uniprot_ac": "A0A3Q1MBB1", "gene_name": "TNS2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] } ] }, { "uniprot_ac": "A0A3Q1MFX2", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1N8V6", "gene_name": "LOC101903026", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S7W5", "gene_name": "PTPRV", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] } ] }, { "uniprot_ac": "A0AAA9S9Q3", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] } ] }, { "uniprot_ac": "A0AAA9SEK4", "gene_name": "PTPRE", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] } ] }, { "uniprot_ac": "A0AAA9SMJ6", "gene_name": "PTPRH", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] } ] }, { "uniprot_ac": "A0AAA9T5N9", "gene_name": "", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] } ] }, { "uniprot_ac": "A0AAA9TAZ9", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] } ] }, { "uniprot_ac": "A0AAA9TFV5", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] } ] }, { "uniprot_ac": "A0AAA9THG9", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] } ] }, { "uniprot_ac": "A0AAA9TWD1", "gene_name": "PTPN20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YUC8", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] } ] }, { "uniprot_ac": "A0AAF6Z8C2", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] } ] }, { "uniprot_ac": "A2VDT1", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] } ] }, { "uniprot_ac": "A5D7P0", "gene_name": "CDC25C", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] } ] }, { "uniprot_ac": "A6H730", "gene_name": "ACP3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] } ] }, { "uniprot_ac": "A7MBD1", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] } ] }, { "uniprot_ac": "A7MBJ4", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] } ] }, { "uniprot_ac": "E1BDH9", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] } ] }, { "uniprot_ac": "E1BEZ8", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] } ] }, { "uniprot_ac": "E1BFE2", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] } ] }, { "uniprot_ac": "E1BIH4", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] } ] }, { "uniprot_ac": "E1BIU8", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJR7", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] } ] }, { "uniprot_ac": "E1BKT4", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] } ] }, { "uniprot_ac": "E1BL76", "gene_name": "CDC25B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] } ] }, { "uniprot_ac": "E1BLR9", "gene_name": "CPD", "activity": [ { "ec_number": "3.4.17.22", "activity": "Releases C-terminal Arg and Lys from polypeptides.", "evidence": [ { "id": "E1BLR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLR9" } ] }, { "ec_number": "3.4.17.22", "activity": "", "evidence": [ { "id": "E1BLR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLR9" } ] } ] }, { "uniprot_ac": "E1BPA0", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] } ] }, { "uniprot_ac": "E1BPU9", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] } ] }, { "uniprot_ac": "F1MD22", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] } ] }, { "uniprot_ac": "F1MDF1", "gene_name": "PTPN18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MGK4", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] } ] }, { "uniprot_ac": "F1MGK5", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MRH9", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] } ] }, { "uniprot_ac": "F1MTZ3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1MXF2", "gene_name": "MDP1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N339", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] } ] }, { "uniprot_ac": "F1N6L3", "gene_name": "PTPN22", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6L3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6L3" } ] } ] }, { "uniprot_ac": "F6RY99", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F6RY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F6RY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ] } ] }, { "uniprot_ac": "G3MXS7", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ] } ] }, { "uniprot_ac": "P0C591", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] } ] }, { "uniprot_ac": "P11064", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] } ] }, { "uniprot_ac": "Q0IID7", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] } ] }, { "uniprot_ac": "Q17QJ3", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] } ] }, { "uniprot_ac": "Q17QM8", "gene_name": "DUSP14", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] } ] }, { "uniprot_ac": "Q2HJ68", "gene_name": "RND1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q2HJ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ68" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q2HJ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ68" } ] } ] }, { "uniprot_ac": "Q2KJ36", "gene_name": "DUSP6", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] } ] }, { "uniprot_ac": "Q2T9S4", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] }, { "ec_number": "3.1.3.18", "activity": "2-phosphoglycolate + H2O = glycolate + phosphate.", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] }, { "ec_number": "3.1.3.18", "activity": "", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] } ] }, { "uniprot_ac": "Q58DB6", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q58DB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DB6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q58DB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DB6" } ] } ] }, { "uniprot_ac": "Q5BIP9", "gene_name": "DUSP18", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] } ] }, { "uniprot_ac": "Q5EA61", "gene_name": "CKB", "activity": [ { 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"database": "UniProtKB", "id": "E1BKU1", "url": "https://www.uniprot.org/uniprotkb/E1BKU1" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "E1BKU1", "url": "https://www.uniprot.org/uniprotkb/E1BKU1" } ], "pmid": "" }, { "name": "glial cell-derived neurotrophic factor receptor binding", "id": "GO:0030116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030116", "evidence": [ { "database": "UniProtKB", "id": "E1BKU1", "url": "https://www.uniprot.org/uniprotkb/E1BKU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKU1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 197, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKU1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKU1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKU1" }, { "id": "PS51362", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51362" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TGF-beta family profile", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 197, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKW9-1", "uniprot_ac": "E1BKW9", "uniprot_id": "E1BKW9_BOVIN", "mass": { "chemical_mass": 108915.0, "monoisotopic_mass": 108915.0 }, "refseq": { "ac": "NP_001289869", "name": "sorting nexin-19", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289869" }, "gene_names": [ { "name": "SNX19", "type": "recommended", "evidence": [ { "id": "E1BKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKW9" } ] }, { "name": "SNX19", "type": "synonym", "evidence": [ { "id": "NP_001289869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289869" } ] } ], "protein_names": [ { "name": "Sorting nexin-19", "type": "recommended", "evidence": [ { "id": "E1BKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKW9/entry#names_and_taxonomy" } ] }, { "name": "sorting nexin-19", "type": "synonym", "evidence": [ { "id": "NP_001289869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289869" } ] } ], "function": [ { "annotation": "Plays a role in intracellular vesicle trafficking and exocytosis. May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).", "evidence": [ { "database": "UniProtKB", "id": "E1BKW9", "url": "https://www.uniprot.org/uniprotkb/E1BKW9#function" }, { "database": "UniProtKB", "id": "ARBA00053440", "url": "https://www.uniprot.org/uniprotkb/ARBA00053440#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKW9", "url": "https://www.uniprot.org/uniprotkb/E1BKW9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SNX19", "url": "https://www.uniprot.org/uniprotkb/E1BKW9", "locus": { "chromosome": "29", "start_pos": 36942605, "end_pos": 36975284, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013076", "url": "https://www.ensembl.org/id/ENSBTAG00000013076" } ] } } ], "crossref": [ { "id": "E1BKW9", "url": "https://alphafold.ebi.ac.uk/entry/E1BKW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013076", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013076", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06893", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06893", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "504649", "url": "https://www.ncbi.nlm.nih.gov/gene/504649", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504649", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504649", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGQHLQS", "url": "https://omabrowser.org/oma/group/CGQHLQS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKW9", "url": "https://www.orthodb.org/?gene=E1BKW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22775", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22775", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22775:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22775:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001289869", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289869", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BKW9", "url": "https://www.uniprot.org/uniprotkb/E1BKW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKW9-1", "url": "https://www.uniprot.org/uniprotkb/E1BKW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTETEILAPERPAGPGVSHLLSSRKLVALGAVLGWLLVIHLLVNVWLLCLLSALLLVLGGWLGSDAIVGASGRLHLERFIPMAVCPPNPEAERQLEQEIDRTIRMIMRDFVSSWYRTVSQEPAFEEEMEAAMRGLVQELRRRMARVDSHALAQRVLTLCGCHLQSYIQAKEAAGKQSGPGEPSQLWEAYCRASAPHPAVQSPSAEVTYTRGIVNVLLQGLVPKPHLETRTGRHIVVELITCNVILPLISKLSDPDWIHLVLVGIFSKARTNPAGVANPLCPASALEQPSVPTSLPLIVEIQGLAEAPSPAAAPVLLSCSEPDGPSHPSPDIEEGHEALEGDLGGVLEERKVENSSSHFLQPLFLSEDAELESPLSELSKETIMLMTPGPFLSASIQDALCALGGSQPLEPKDGKGPEGIEGAEAEEGPGTETEPGLLASMLNSCPEIQIDTADKEGEQGNDACLTTLLPSPERICPPRPSCLEKDLTNGGSSLDSSLPQVLLSSSPPGPLSSATFNFESLGSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALDGESSGGLQHVAYHTVNRRYREFLNLQTRLEEKSDLRKFIKNVKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEMQEFLALNTDARIAFVKKPFVVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAETENKPQTEGKKASKSRLRFSSSKIAPALNITEAHEKVLYCLQDSGVESETLSVSGMESFIEKQAKLLEVQPADAPGRDSEQTAEGCVDGRVSDAAAPAQGLSSSDPGTETELADTALDLLVLLLMEQWRWLCTESVQKVLHLVFGTLIQRWLEVQVAHLTCPQRWVQYLRLLQESIWPGGALPKCPRPVRTPEQKAAAEKQALQSLMGVLPDVIVEILGENKCRLSWSLVLESLQQPLINRHLIYCLWDIILELLELSASAEESAVTSSTADTPGRRASPLSQRPLSRFFEG", "length": 1000, "header": "tr|E1BKW9-1|E1BKW9_BOVIN Isoform 1 of Sorting nexin-19 OS=Bos taurus OX=9913 GN=SNX19 PE=3 SV=3 CANONICAL=E1BKW9-1" }, "isoforms": [ { "isoform_ac": "E1BKW9-1", "url": "https://www.uniprot.org/uniprotkb/E1BKW9/entry#E1BKW9-1", "sequence": { "sequence": "MKTETEILAPERPAGPGVSHLLSSRKLVALGAVLGWLLVIHLLVNVWLLCLLSALLLVLGGWLGSDAIVGASGRLHLERFIPMAVCPPNPEAERQLEQEIDRTIRMIMRDFVSSWYRTVSQEPAFEEEMEAAMRGLVQELRRRMARVDSHALAQRVLTLCGCHLQSYIQAKEAAGKQSGPGEPSQLWEAYCRASAPHPAVQSPSAEVTYTRGIVNVLLQGLVPKPHLETRTGRHIVVELITCNVILPLISKLSDPDWIHLVLVGIFSKARTNPAGVANPLCPASALEQPSVPTSLPLIVEIQGLAEAPSPAAAPVLLSCSEPDGPSHPSPDIEEGHEALEGDLGGVLEERKVENSSSHFLQPLFLSEDAELESPLSELSKETIMLMTPGPFLSASIQDALCALGGSQPLEPKDGKGPEGIEGAEAEEGPGTETEPGLLASMLNSCPEIQIDTADKEGEQGNDACLTTLLPSPERICPPRPSCLEKDLTNGGSSLDSSLPQVLLSSSPPGPLSSATFNFESLGSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALDGESSGGLQHVAYHTVNRRYREFLNLQTRLEEKSDLRKFIKNVKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEMQEFLALNTDARIAFVKKPFVVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAETENKPQTEGKKASKSRLRFSSSKIAPALNITEAHEKVLYCLQDSGVESETLSVSGMESFIEKQAKLLEVQPADAPGRDSEQTAEGCVDGRVSDAAAPAQGLSSSDPGTETELADTALDLLVLLLMEQWRWLCTESVQKVLHLVFGTLIQRWLEVQVAHLTCPQRWVQYLRLLQESIWPGGALPKCPRPVRTPEQKAAAEKQALQSLMGVLPDVIVEILGENKCRLSWSLVLESLQQPLINRHLIYCLWDIILELLELSASAEESAVTSSTADTPGRRASPLSQRPLSRFFEG", "length": 1000, "header": "tr|E1BKW9-1|E1BKW9_BOVIN Isoform 1 of Sorting nexin-19 OS=Bos taurus OX=9913 GN=SNX19 PE=3 SV=3 CANONICAL=E1BKW9-1" }, "locus": { "chromosome": "29", "start_pos": 36974805, "end_pos": 36943565, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017386.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017386.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017386.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017386.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:504649", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504649", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BNC7-1", "protein_name": "Sorting nexin-19", "gene_name": "SNX19", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAEAAALSQEPAAEPSCSLGHLFSSRKLLAVGAVLGWLLVIHLLVNVWLLCLLSALLLVLGGWLGSDAIVGASGRLHLERFIPLAICPPNPEAERQLEQEIDRTIRLIMRDFVSSWYRTVSQEPAFEEEMEAAMRGLVQELRRRMAMVDRHALAQRVLTLCGCHLQSYIQAKEATAGKQSGTVEPSQLWEAYCRTTAPHPAVQSPSTEVTYTREIVDLLLKGLVPKPHLETRTGRHVVVELITCNVILPLISKLSDPDWIHLVLVGIFSKARNNPAGTMKPLCQASTLEQPSVPTSLPLIVEVQSLPKVRAPSPAAVPVLLDCSEPDGPSHLSPEVEEGREALEGDLGVVLEERRVGNNPSHFLQPGITGPLFLSEDAELESPLSELGKETIMLMTPGNFLSDKIPNVLCVLGGSHSLEAKDAEGSEGVEEAEAEEGPGTETDSGLLVSMLNTCPEIHIDTADKEVEQGDVTSLATLLASPERTCPPRPPCLEKELTNGVSALDPSLPQVLLSSSPPGPLSAATFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALEGESSSGLQQLAYHTVNRRYREFLNLQTRLEEKSDLRKLLKNVKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFVVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAETESKPQAEGKKASKSRLRFSSSKIAPALNIAEAHEKILYCLQEGSVESEVLSMSGMESFIEKQTKLLEMQPAEAPGKDSEQISKECVDGFEAEAAVPAQDLSNNDAGAETALANTALDLLLLLLMEQWRWLCTENVQKVLHLIFGTLIQRWLEVQVANLTCPQRWVQYLRLLQESIWPGGVLPKYPRPVRTQEQKVAAEEQALQSLMGVLPDIVVEILGVNKCRLSWSLVLESLQQPLINRHLIYCLWDLILEFLDLNASVEESAMTTSASETPSNPKKMGVSP", "length": 1002 }, "evidence": [ { "id": "E1BKW9", "url": "https://omabrowser.org/oma/group/E1BKW9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZJR4-1", "protein_name": "Sorting nexin-19", "gene_name": "SNX19", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPCHRELLALLAVLGWLLVLLLDLRALALLCGTAALLGGWLGPRALSRPGWRLRLERFAGSLRPAAASPEAEEQLEQEISSTIRKVVRDFVSSWYCTVSSECAFEAEVEKAMAGLAAELRRRMARVDRQALARRLLLLCGHHLQSYLQALRGRGPLWQEYRQIAGLHPALCSPAAEVSYARASVELLLRALVPRPHLETRTGHFVVVELVACNVLLPAVRKMADPDWINLLLVGAFPRKAQGEEPSPAAPVPDSLPLIVQPDVAPAVPLLSPSPGREAGAGGEDGADVPSEPPRSEGVVLRPRGLGLLFPYEGLELDSPGQDVELLAPSPAGEFLDEPLPDVPAPLEGADTSEDGMGDLEDGHTTSSDASLLLPSAYALGPCPDIQIDPVMETEEDSPKKPSVQRPCSLGKELGTPEAPPQSPSDPGQPLPLLSSSPTAPISTFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTIKYETALEGEVVGSLQQMAYHTVNRRYREFLNLQTRLEEKPELRKFLKNIKGPKKLFPDLPFGNMDSDKVEARKSLLESFLKQLCAVPEIANSEEVQEFLALNTDARIAFVKKPFVVSRIDKIVVNAIVDTLKTAFPRSEPQSPTEDLSESEVDGKCQPDGKKANKSRLRFPSSKITPVLSVSEAHDRIVYSVREGSAVSGTLSLAAMESFIQKQEKVLEAVPSKAPEGEGSEEAKEKSVQEDIDGLSTSEQGVHLDTDTDSETALADLALDLLRLLLMDHWTWLGMENIQKVFHLLFGTLIQRFISTWEQGCVFWMWHADLMLSPLIVQKKSFGISWWLEVQVVNLTCTQRWVQYLQLLQESIWPGGVLPEIPKPARTEEQKKAAAEQALQSLMGILPNVVQEILGTDKCRMSWSLVLESLGHPVINRHLVFCLLDVLLEFLVLKGSSDELETATVVPPDSSGLEKAGGAAH", "length": 957 }, "evidence": [ { "id": "E1BKW9", "url": "https://omabrowser.org/oma/group/E1BKW9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZXB9-1", "protein_name": "Sorting nexin-19", "gene_name": "Snx19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKAQTVSPAQGNIPESSYVNSNLWSSRKLMVVGVLLGWLLVIHLLVNVWLLILLCASLVVLGGWLGSTAIVGASGQLHLERFISITTCPPCPEAERHLEQEINCTIQMIIRDFVLSWYRSVSHEKTFEAEMEASMKGLVQELRRRMSIVDSHALTQRVLTLCGCHLQSYIQAKGATAKEQSCPVEPSQLWDAYCQVTTPHPAMSCPTTEVTYARGIVNLILKELVPKPHLETRTGRHVVVELITCNVILPLISKLSDPDWIHLILVSIFSKYKQDAAQGTKPPSSPCVLEQPSVPTSLPLMVEVESLPVGKASSPVAAPVHLASSEPAPSPEIEEGHEAVEGELPGMLEERKVGNNSSHFLQPDIRGPLFLCEDSELESPLSELGKETIMLMTPGNFLSHRIQDALCALDDSQALEPRDGEGSECMEGAEAEEAPGAETETGTLVSMLNCPEIQIDPADKEAEQGDDASLTALLEEPEKPCLQRPSCLDKGLGSGACSLEPAVPPLSLSSSPPGPLSSATFSFESLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALSGENSSGLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLPFGNMDSDRVEARKSLLESFLRQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKASKSRLRFSSSKIAPALSIAEAQDKILYCLQEGNSESEVLSMSGMESFIEKQTKLLQMQPAEVPDKEPQQVPKESVDSGLLDKAVVSQELNKSDPGTETELADTAFDLILLLLMEQWKWLCTENMQKFLRLVFGTLVQRWLEVQVANLTCPQRWAQYLRLLRESIWPGGVLPKFPRPGRTQAQKAATEKQALQSLMGLLPDFLVEILGVHKCQLSWSLVLESFQQPLINRHLIYCLGDIILEFLDLSAAVEECAPTTSASDSPGSLKKMAVST", "length": 997 }, "evidence": [ { "id": "E1BKW9", "url": "https://omabrowser.org/oma/group/E1BKW9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P4T1-1", "protein_name": "Sorting nexin-19", "gene_name": "Snx19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKAQTVSPTQGTISESSYVHSNLWSSRKLMIVGVLVGWLLVIHLLVNMWLLILLCASLVALGGWLGSTAILGASGQLHLERFITITTCPPCPEAERQLEQEINRTIQMIIRDFVLSWYRSVSHEPAFEAEMEAAMKGLVQELRRRMSIVDSHALTQRVLTLCGCHLQSYIQAKEATAKEQSCPVQPSQLWDAYCQVTAPHPAMSCPTTEVTYARGIVNLILKELVPKPHLETRTGRHVVVEVITCNVILPLISKLSDPDWIHLILVSIFSKYRHDAAQGTKPPCSSSVLEQPSVPTSLPLIVEVESLPVGKASSPATAPVHLTSSEPAPSPEIEEGHEAVEGDLPGMLEEKKVGNSSSHFLQPDIRGPLFLCEDSELESPLSELSKETILLMTPGNFLSDRIQDALCALDDSGALEPKDGEGSECMEGAEAEEAPGTDTETGMLVSVLNCPEIQIDTADKEVEQGDDTSLTALLEEPEKPCPLRPSCLDKDLASGVCSLEPAMPPVPLSSSPPGPLSSATFSFESLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETVLNGENSSGLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIGNSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKASKSRLRFSSSKIAPALSIAEAQDKILYCLQEGNSESEVLSMSGMESFIEKQTKLLRIQPAEVPDKDPQQVPKEYVDSGLLDKAVVAQELNKSGPGTETELADTAFDLILLLLMEQWKWLCTESMQKFLHIIFGTLVQRWLEVQVANLTCPQRWAQYLHLLRESIWPGGVLPKFPRPGRTQAQKAATEKQALQSLMDLLPDFLVEILGVNKCRLSWSLVLESFQQPLINRHLIYCLGDIILELLDLSASVEECAPATSASDSPGSLKKMAVST", "length": 997 }, "evidence": [ { "id": "E1BKW9", "url": "https://omabrowser.org/oma/group/E1BKW9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92543-1", "protein_name": "Sorting nexin-19", "gene_name": "SNX19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKTETVPPFQETPAGSSCHLNNLLSSRKLMAVGVLLGWLLVIHLLVNVWLLCLLSALLVVLGGWLGSSLAGVASGRLHLERFIPLATCPPCPEAERQLEREINRTIQMIIRDFVLSWYRSVSQEPAFEEEMEAAMKGLVQELRRRMSVMDSHAVAQSVLTLCGCHLQSYIQAKEATAGKNGPVEPSHLWEAYCRATAPHPAVHSPSAEVTYTRGVVNLLLQGLVPKPHLETRTGRHVVVELITCNVILPLISRLSDPDWIHLVLVGIFSKARDPAPCPASAPEQPSVPTSLPLIAEVEQLPEGRASPVAAPVFLSYSEPEGSAGPSPEVEEGHEAVEGDLGGMCEERKVGNNSSHFLQPNVRGPLFLCEDSELESPLSELGKETIMLMTPGSFLSDRIQDALCALESSQALEPKDGEASEGAEAEEGPGTETETGLPVSTLNSCPEIHIDTADKEIEQGDVTASVTALLEGPEKTCPSRPSCLEKDLTNDVSSLDPTLPPVLLSSSPPGPLSSATFSFEPLSSPDGPVIIQNLRITGTITAREHSGTGFHPYTLYTVKYETALDGENSSGLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLPLGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAETESKPQTEGKKASKSRLRFSSSKISPALSVTEAQDKILYCLQEGNVESETLSMSAMESFIEKQTKLLEMQPTKAPEKDPEQPPKGRVDSCVSDAAVPAQDPSNSDPGTETELADTALDLLLLLLTEQWKWLCTENMQKFLRLIFGTLVQRWLEVQVANLTSPQRWVQYLLLLQESIWPGGVLPKFPRPVRTQEQKLAAEKQALQSLMGVLPDLVVEILGVNKCRLSWGLVLESLQQPLINRHLIYCLGDIILEFLDLSASVEESAATTSASDTPGNSKRMGVSS", "length": 992 }, "evidence": [ { "id": "E1BKW9", "url": "https://omabrowser.org/oma/group/E1BKW9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "E1BKW9", "url": "https://www.uniprot.org/uniprotkb/E1BKW9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "chondrocyte differentiation", "id": "GO:0002062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002062", "evidence": [ { "database": "UniProtKB", "id": "E1BKW9", "url": "https://www.uniprot.org/uniprotkb/E1BKW9" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "E1BKW9", "url": "https://www.uniprot.org/uniprotkb/E1BKW9" } ], "pmid": "" }, { "name": "insulin secretion", "id": "GO:0030073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030073", "evidence": [ { "database": "UniProtKB", "id": "E1BKW9", "url": "https://www.uniprot.org/uniprotkb/E1BKW9" } ], "pmid": "" }, { "name": "dense core granule maturation", "id": "GO:1990502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990502", "evidence": [ { "database": "UniProtKB", "id": "E1BKW9", "url": "https://www.uniprot.org/uniprotkb/E1BKW9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "E1BKW9", "url": "https://www.uniprot.org/uniprotkb/E1BKW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKW9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1000, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKW9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKW9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKW9" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 533, "end_pos": 663, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKW9" }, { "id": "PS51207", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51207" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PXA", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 270, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 354, "end_pos": 356 }, { "start_pos": 737, "end_pos": 739 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKX2-1", "uniprot_ac": "E1BKX2", "uniprot_id": "E1BKX2_BOVIN", "mass": { "chemical_mass": 77011.0, "monoisotopic_mass": 77011.0 }, "refseq": { "ac": "XP_002693950", "name": "protein phosphatase 1 regulatory subunit 15B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693950" }, "gene_names": [ { "name": "PPP1R15B", "type": "recommended", "evidence": [ { "id": "E1BKX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" } ] }, { "name": "PPP1R15B", "type": "synonym", "evidence": [ { "id": "XP_002693950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693950" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 15B", "type": "synonym", "evidence": [ { "id": "E1BKX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX2/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 15B", "type": "synonym", "evidence": [ { "id": "XP_002693950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693950" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKX2", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PPP1R15B", "url": "https://www.uniprot.org/uniprotkb/E1BKX2", "locus": { "chromosome": "16", "start_pos": 2150477, "end_pos": 2156845, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013074", "url": "https://www.ensembl.org/id/ENSBTAG00000013074" } ] } } ], "crossref": [ { "id": "E1BKX2", "url": "https://alphafold.ebi.ac.uk/entry/E1BKX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013074", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013074", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538754", "url": "https://www.ncbi.nlm.nih.gov/gene/538754", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019512", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019512", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538754", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538754", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GDSPTQC", "url": "https://omabrowser.org/oma/group/GDSPTQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKX2", "url": "https://www.orthodb.org/?gene=E1BKX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16489:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16489:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10472", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10472", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10488", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10488", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002693950", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693950", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BKX2", "url": "https://www.uniprot.org/uniprotkb/E1BKX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKX2-1", "url": "https://www.uniprot.org/uniprotkb/E1BKX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPAADSSREPDPRFRLPSFFPRPSGSGTSRFPAPLSPEPDPRLAPSPPPEARSSSWMQLLSQLLAPLPGLLQKLLVWSQLFGGMIPTRWLDFAGGYGLLRARKEPAAPSAPKALSSLRLDPSADAAASPLDWLEGGLHWQCSPPDLELELKPKGRALDSAAHAFLLEQPLWGVELVPRSVQARLFSDPELGPSPSGPLSVQRLSNVSVVSYLLNPSYLDCLPRVELSYQSSVGSCELVDFQALSPESGCLDEASSYPQPLNAEMAPASWQGCPPLSREGLPEIHHLRMKRLEFLQQASKGQALPTPDQDHGYHSLEEEHSLLRMEPKHFGDSPTQCVPAAGAVPGTAQEPTEEKTELLIREVPFGLERQGPSGGILSCETGQELGEDQISVVDSSDIDDDLPISARPACSNKLIDYILGGAASDLETSSDSEDVDWDEDVEDDGFDSDSSFSESDLEQDSEGLHLWNSFYSVDPYNPQNFTATIQTAARILPGNPSDSEKDLSDKSDLGNSPQTESLPEFPDHNSGDDDDWESSADEAESLKLWNSFCNSDDPYNLLNFKAPFQTGKNWKSYLDSERPSEPISECHTLLSCKGQLLGSPESKCPDLVRGVVLSGETHTHIRRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEEAIGYCLTFEHREKMFNRLQQTCFKGLNVFEQC", "length": 698, "header": "tr|E1BKX2-1|E1BKX2_BOVIN Isoform 1 of Protein phosphatase 1 regulatory subunit 15B OS=Bos taurus OX=9913 GN=PPP1R15B PE=3 SV=2 CANONICAL=E1BKX2-1" }, "isoforms": [ { "isoform_ac": "E1BKX2-1", "url": "https://www.uniprot.org/uniprotkb/E1BKX2/entry#E1BKX2-1", "sequence": { "sequence": "MEPAADSSREPDPRFRLPSFFPRPSGSGTSRFPAPLSPEPDPRLAPSPPPEARSSSWMQLLSQLLAPLPGLLQKLLVWSQLFGGMIPTRWLDFAGGYGLLRARKEPAAPSAPKALSSLRLDPSADAAASPLDWLEGGLHWQCSPPDLELELKPKGRALDSAAHAFLLEQPLWGVELVPRSVQARLFSDPELGPSPSGPLSVQRLSNVSVVSYLLNPSYLDCLPRVELSYQSSVGSCELVDFQALSPESGCLDEASSYPQPLNAEMAPASWQGCPPLSREGLPEIHHLRMKRLEFLQQASKGQALPTPDQDHGYHSLEEEHSLLRMEPKHFGDSPTQCVPAAGAVPGTAQEPTEEKTELLIREVPFGLERQGPSGGILSCETGQELGEDQISVVDSSDIDDDLPISARPACSNKLIDYILGGAASDLETSSDSEDVDWDEDVEDDGFDSDSSFSESDLEQDSEGLHLWNSFYSVDPYNPQNFTATIQTAARILPGNPSDSEKDLSDKSDLGNSPQTESLPEFPDHNSGDDDDWESSADEAESLKLWNSFCNSDDPYNLLNFKAPFQTGKNWKSYLDSERPSEPISECHTLLSCKGQLLGSPESKCPDLVRGVVLSGETHTHIRRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEEAIGYCLTFEHREKMFNRLQQTCFKGLNVFEQC", "length": 698, "header": "tr|E1BKX2-1|E1BKX2_BOVIN Isoform 1 of Protein phosphatase 1 regulatory subunit 15B OS=Bos taurus OX=9913 GN=PPP1R15B PE=3 SV=2 CANONICAL=E1BKX2-1" }, "locus": { "chromosome": "16", "start_pos": 2156646, "end_pos": 2151481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017382.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017382.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017382.5", "url": "https://www.ensembl.org/id/ENSBTAP00000017382.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538754", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538754", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZP67-1", "protein_name": "Protein phosphatase 1, regulatory subunit 15B", "gene_name": "Ppp1r15b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METGTHRARKRPTSRMGSWFRLPFLRRSHACTSEFPKPSSRPNLEVSARPEPRTRYWTKLLSQLLALLPSLLQKLLIWSQLFGGMIPTRWLDFSASYSALRALRGREESAAPTVQKSLNSLRLDSSSEDLVVSSLDWLEEGLQGQCSSSDLELKFKAQERALDSTAHTFLLEQQLWGVELLPGSLQTGLVSHRELGSSSSGPLSTQSLGNFKVVSYLLNPSYLDCLPQLELRCQNSVGGGQLVDFRTLSPESCYLSEDACHPQPLCAEMSATAWRRCPPLSTEGLPEIHHLRMKRLEFLQANKGQELPTPDQDNGYHSLEEEHCLLRMDPQHCTDKAAQAVSPAGASPQPTEKKVELVVEEVLQSPQGSSLSCELSVQKECEDYSDIGGNLPVSTRPACTNKLIDYILGGASSDLDTSSDSESEDWDEEPEDDGFDSDGSLSESDREQDSEGLHLWNSFYSVDPYNPQNFTATIQTAARIAPRDPSDSEKSWSGNSDVGSSQATLLPQTPDQSSGEEDDWESSADEAENLRLWNSFCNSEDPYNLLNFKAPFQTSGKSWKGSQASSEATVVFSGHQTLLSCEAQLLESQEDNCPGCGLGEALSGERYTHIKRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEVAIGYCLTFEHRERVFSRLQDHVSKDLLLYSSAKQREQPAALTHSISYLRGFS", "length": 707 }, "evidence": [ { "id": "E1BKX2", "url": "https://omabrowser.org/oma/group/E1BKX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LIA2-1", "protein_name": "Protein phosphatase 1 regulatory subunit 15B", "gene_name": "PPP1R15B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPAEDGSRDRAAPRPRSRFRLPFFPWRSRAGTSKFPAPPAPGHSGDPRQASCPLPEARSSSWMQLLSQLFAPLPGLFQKLLIWSQLFGGMIPTRWLDFTGGYGALRALKAREEPAAPTAPKSLLRFDPSADAAANPLDWLEEGIHWQCSPADLALELKAKGRALESAAHAFLLEQQQLWRLELVPGSFQASLISDRELGPSPSEPLNVQRLSNVNVVSYLLNSSYLDGLPRVELSYQSSAGRGKLVDFQALSPESGSLDEVLSSHPQPLNAEIAHASWQECPPLSREGLPEIHHLRMKRLEFLQQASKGQGLPTPDQDHGYHSLEEEHSLLRMDLKHPRDSPTQCIPVPGTAQEPTEEKIELLTEEVPLALERHDSSESCASCEFPAEQEPGEDQISVVDNSDIEDDLPTSARPACSNKLIDYILGGAASDLETSSDSEGEDWDEDAEDDGFDSDGSLSDSDLERDSEGLHLWNSFYSVDPYNPQNFTATIQTAARILPRESSDSEKDLSDQSDVENSPQTGSLPESPDHNSGEDDDWESSADEAESLRLWNSFCNSDDPYNLLNFKAPFQTSGKNGKGCRDSERPPESIVTISDCHSLLSCEVHLLGSRENECPDLVQGGVLSGERHTHTQRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEDAIGYCLTFEHRERIFNRLQETCFKELNVFEQC", "length": 709 }, "evidence": [ { "id": "E1BKX2", "url": "https://omabrowser.org/oma/group/E1BKX2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5SWA1-1", "protein_name": "Protein phosphatase 1 regulatory subunit 15B", "gene_name": "PPP1R15B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPGTGGSRKRLGPRAGFRFWPPFFPRRSQAGSSKFPTPLGPENSGNPTLLSSAQPETRVSYWTKLLSQLLAPLPGLLQKVLIWSQLFGGMFPTRWLDFAGVYSALRALKGREKPAAPTAQKSLSSLQLDSSDPSVTSPLDWLEEGIHWQYSPPDLKLELKAKGSALDPAAQAFLLEQQLWGVELLPSSLQSRLYSNRELGSSPSGPLNIQRIDNFSVVSYLLNPSYLDCFPRLEVSYQNSDGNSEVVGFQTLTPESSCLREDHCHPQPLSAELIPASWQGCPPLSTEGLPEIHHLRMKRLEFLQQASKGQDLPTPDQDNGYHSLEEEHSLLRMDPKHCRDNPTQFVPAAGDIPGNTQESTEEKIELLTTEVPLALEEESPSEGCPSSEIPMEKEPGEGRISVVDYSYLEGDLPISARPACSNKLIDYILGGASSDLETSSDPEGEDWDEEAEDDGFDSDSSLSDSDLEQDPEGLHLWNSFCSVDPYNPQNFTATIQTAARIVPEEPSDSEKDLSGKSDLENSSQSGSLPETPEHSSGEEDDWESSADEAESLKLWNSFCNSDDPYNPLNFKAPFQTSGENEKGCRDSKTPSESIVAISECHTLLSCKVQLLGSQESECPDSVQRDVLSGGRHTHVKRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEDAIGYCLTFEHRERMFNRLQGTCFKGLNVLKQC", "length": 713 }, "evidence": [ { "id": "E1BKX2", "url": "https://omabrowser.org/oma/group/E1BKX2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BFW3-1", "protein_name": "Protein phosphatase 1 regulatory subunit 15B", "gene_name": "Ppp1r15b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METGTHRARKRPGPRLGSWFRLPFLRRSHACSSEFPPPSSRQNPGNSALPERRTRYWTKLLSQLLALLPSLFQKLLLWSQLFGGLIPTRWLDFAASYSALRALRGREESAAPTVQKSLSSLRLDSSEDLVVSSLDWLEEGLQWQCSSSDLELKLKAQERALDSAAPTFLLEQQLWGVELLPSSLQAGLVSHRELDSSSSGPLSVQSLGNFKVVSYLLNPSYLDYLPQLGLRCQSSAGGGQFVGFRTLTPESCYLSEDGCHPQPLRAEMSATAWRRCPPLSTEGLPEIHHLRMKRLEFLQANKGQELPTPDQDNGYHSLEEEHNLLRMDPQHCTDNPAQAVSPAADRPEPTEKKPELVIQEVSQSPQGSSLFCELPVEKECEEDHTNATDLSDRGESLPVSTRPVCSNKLIDYILGGAPSDLEASSDSESEDWGEEPEDDGFDSDGSLSESDVEQDSEGLHLWNSFHSVDPYNPQNFTATIQTAARIAPRDPSDSGTSWSGSCGVGSCQEGPLPETPDHSSGEEDDWEPSADEAENLKLWNSFCHSEDPYNLLNFKAPFQPSGKNWKGRQDSKASSEATVAFSGHHTLLSCKAQLLESQEDNCPGCGLGEALAGERYTHIKRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEVAIGYCLAFEHREKMFNRLRIESKDLLLYSNVKK", "length": 697 }, "evidence": [ { "id": "E1BKX2", "url": "https://omabrowser.org/oma/group/E1BKX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "eukaryotic initiation factor eIF2 binding", "id": "GO:0071074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071074", "evidence": [ { "database": "UniProtKB", "id": "E1BKX2", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "E1BKX2", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" } ], "pmid": "" }, { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "E1BKX2", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" } ], "pmid": "" }, { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "E1BKX2", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "protein phosphatase type 1 complex", "id": "GO:0000164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000164", "evidence": [ { "database": "UniProtKB", "id": "E1BKX2", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BKX2", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "E1BKX2", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" } ], "pmid": "" }, { "name": "regulation of protein metabolic process", "id": "GO:0051246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051246", "evidence": [ { "database": "UniProtKB", "id": "E1BKX2", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKX2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 698, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKX2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKX2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" }, { "id": "PF10488", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10488" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein phosphatase 1 regulatory subunit 15A/B C-terminal", "eco_id": "ECO_0000259", "start_pos": 458, "end_pos": 684, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX2" }, { "id": "PF10472", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10472" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein phosphatase 1 regulatory subunit 15B N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 399, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 480, "end_pos": 482 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKY5-1", "uniprot_ac": "E1BKY5", "uniprot_id": "E1BKY5_BOVIN", "mass": { "chemical_mass": 41108.0, "monoisotopic_mass": 41108.0 }, "refseq": { "ac": "XP_002687957", "name": "leucine-rich repeat and transmembrane domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687957" }, "gene_names": [ { "name": "LRTM2", "type": "recommended", "evidence": [ { "id": "E1BKY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKY5" } ] }, { "name": "LRTM2", "type": "synonym", "evidence": [ { "id": "XP_002687957", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687957" } ] } ], "protein_names": [ { "name": "Leucine rich repeats and transmembrane domains 2", "type": "synonym", "evidence": [ { "id": "E1BKY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKY5/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat and transmembrane domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_002687957", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687957" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKY5", "url": "https://www.uniprot.org/uniprotkb/E1BKY5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LRTM2", "url": "https://www.uniprot.org/uniprotkb/E1BKY5", "locus": { "chromosome": "5", "start_pos": 108258657, "end_pos": 108251306, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021995", "url": "https://www.ensembl.org/id/ENSBTAG00000021995" } ] } } ], "crossref": [ { "id": "E1BKY5", "url": "https://alphafold.ebi.ac.uk/entry/E1BKY5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021995", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021995", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100297677", "url": "https://www.ncbi.nlm.nih.gov/gene/100297677", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100297677", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100297677", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QISWIAC", "url": "https://omabrowser.org/oma/group/QISWIAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKY5", "url": "https://www.orthodb.org/?gene=E1BKY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45773", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45773", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45773:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45773:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002687957", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687957", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BKY5", "url": "https://www.uniprot.org/uniprotkb/E1BKY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKY5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAPGGSPEPRGTKGHTWLALWRRISWLACWIALCTAEAVPACPFPCTCDGRGLQVDCSGLGLTAPPPDLPAATRSLLLLNNRLSSLPGGAFANLSGLQRLDLSNNFLDRLPRMAFGDLANLTELQLRNNSLRALDATLLRPLPRLRHLDLSLNGLSRLPPGLFDGLPALRSLSLRANRLQSLDRRTFEPLAGLQLLQVADNPWECDCHLRDFKRWLEWFSYRGGRLDQLACTLPKELRGKDMRMVPMEMFNYCSQLEDQNSSAGQEVSGPPCTKASPEPAKPKPGPEPEPEPSTACPQKQRPRPVSVRRAIGTVIIAGVVCGVVCIMMVVAAAYGCIYASLMAKYHRELKKRQPLMGDPEGEQEDQKQISSVA", "length": 374, "header": "tr|E1BKY5-1|E1BKY5_BOVIN Isoform 1 of Leucine rich repeats and transmembrane domains 2 OS=Bos taurus OX=9913 GN=LRTM2 PE=3 SV=2 CANONICAL=E1BKY5-1" }, "isoforms": [ { "isoform_ac": "E1BKY5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKY5/entry#E1BKY5-1", "sequence": { "sequence": "MLAPGGSPEPRGTKGHTWLALWRRISWLACWIALCTAEAVPACPFPCTCDGRGLQVDCSGLGLTAPPPDLPAATRSLLLLNNRLSSLPGGAFANLSGLQRLDLSNNFLDRLPRMAFGDLANLTELQLRNNSLRALDATLLRPLPRLRHLDLSLNGLSRLPPGLFDGLPALRSLSLRANRLQSLDRRTFEPLAGLQLLQVADNPWECDCHLRDFKRWLEWFSYRGGRLDQLACTLPKELRGKDMRMVPMEMFNYCSQLEDQNSSAGQEVSGPPCTKASPEPAKPKPGPEPEPEPSTACPQKQRPRPVSVRRAIGTVIIAGVVCGVVCIMMVVAAAYGCIYASLMAKYHRELKKRQPLMGDPEGEQEDQKQISSVA", "length": 374, "header": "tr|E1BKY5-1|E1BKY5_BOVIN Isoform 1 of Leucine rich repeats and transmembrane domains 2 OS=Bos taurus OX=9913 GN=LRTM2 PE=3 SV=2 CANONICAL=E1BKY5-1" }, "locus": { "chromosome": "5", "start_pos": 108257653, "end_pos": 108251991, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029331.7", "url": "https://www.ensembl.org/id/ENSBTAT00000029331.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029331.5", "url": "https://www.ensembl.org/id/ENSBTAP00000029331.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100297677", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100297677", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9Q6C3-1", "protein_name": "Leucine-rich repeat and transmembrane domain-containing protein 2", "gene_name": "lrtm2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQLCTAPTVGRRRRGNPDSQGFLGVLSVCATLLQLCAGCPSECVCNSLEANCSGRSLVSVPALTSLPEGTHTLLLANNRLSSLPLSAFANLSTLETLDLSNNYLDNLPSRLFRELSNLSELSLRNNSLTVLDRELFRGLTHLRKLDLSLNGLAAVPLGLLDELQQLTWLSLAGNRLHALERATFEPLVNLQHLELGMNPWECDCNLRDFKHWMEWLIYRGGYVDAVECTLPKDLRGRDIRGVPVEMFNYCLQLEDENGGGTGSTKGGSPPCFRGTAAPSSDSAVVRTEAELPDCVKQRYRPVSVRRAIGTVVIAGVVCGIVCIMMVAAAAYGCIYASLMAKYQRELKKRQPLMGDAEAETDPEEKQISSVA", "length": 371 }, "evidence": [ { "id": "E1BKY5", "url": "https://omabrowser.org/oma/group/E1BKY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0YUW0-1", "protein_name": "Leucine rich repeats and transmembrane domains 2", "gene_name": "LRTM2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MYPQPRAQPPSPPARSLSLCSLLAGDYSSFPTLPAERAAPRPHVWCGQPGCWPPSPCQLEPSERLPGEKARSAGFALGLPRVRWKSPVSQRSVRPRAGGQAWRSLRTPGLSTGLTGGCEGALERTKMLPMSASHQWRSRSLMRWQEACLLGCWLSLCAAESFFACPSSCKCNSGILEVDCSGLGLSSIPSDIPTNTRTFLFLNNKLSILPGPVFSNLSALQRLDLSNNFLDQLPQNIFSDLGNLTELQLRNNSIRALDKDLLQHTALLRQLDLSINGLAQIPSGIFDDLPALRSLSLRSNRLQSLDRVTFEPLTSLQQLQVGDNPWECDCNLRDFKHWMEWFSYRGGKIDQLACTLPKELKGKDMRMVPMEMFNYCSQLDDENSSTVLDNTGPPCTKGSPTPSKTKSGPEPEVEPSVGCPQKQRYRPVSVRRAIGTVIIAGVVCGIVCIMMVVAAAYGCIYASLMAKYHRELKKRQPLMGDTEGEHEEQKQISSVA", "length": 496 }, "evidence": [ { "id": "E1BKY5", "url": "https://omabrowser.org/oma/group/E1BKY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZPP7-1", "protein_name": "Leucine-rich repeats and transmembrane domains 2", "gene_name": "Lrtm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAPGGGPEQRSKLVLQWRQLSWITCWIALCAVEVLPACPFSCTCDSRSLEVDCSGLGLTTVPPDVPAATQSLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDQLPRSVFQDLVNLTELQLRNNSIRTLDRDLLQHSPRLRHLDLSINGLAQLPQGLFDGLLALRSLSLRSNRLQSLDRLTFEPLASLQLLQVGDNPWECDCNLREFKHWLEWFSYRGGRLDQLACTLPKELRGKDMRAVPMEMFNYCSQLEDENSAGLDAPGPPCTKASPEPPKPKPGAEPEPEPSTACPQKQRYRPVSVRRAIGTVIIAGVVCGIVCIMMVVAAAYGCIYASLMAKYHRELKKRQPLMGDPEGEHEDQKQISSVA", "length": 369 }, "evidence": [ { "id": "E1BKY5", "url": "https://omabrowser.org/oma/group/E1BKY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SHR9-1", "protein_name": "Leucine rich repeats and transmembrane domains 2", "gene_name": "LRTM2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLAPGSSPKPRTRLVLQWKPISWLTYWIALCAAEALPACPFSCSCDSRSLEVDCSGLGLTVVPPDVPAATRTLLLQNNRLSSLPSWAFANLSSLQRLDLSNNFLDRLPRAAFGDLANLTELQLRNNSLRALDPELLRHLPRLRHLDLSLNGLARLPPGLFDGLPALRSLSLRANRLQSLDRLTFEPLASLQLLQVGDNPWECDCHLRDFKHWLEWFSYRGGRLDQLACTLPKELRGKDMRVVPMEMFNYCSQLEDENSSAGLEVPGPPCTKASLEPAKPKPGPEPEPEPSTACPQKQRPRPVSVRRAIGTVIIAGVVCGIVCIMMVVAAAYGCIYASLMAKYHRELKKRQPLMGDPEGEHEDQKQISSVA", "length": 370 }, "evidence": [ { "id": "E1BKY5", "url": "https://omabrowser.org/oma/group/E1BKY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BGX3-1", "protein_name": "Leucine-rich repeat and transmembrane domain-containing protein 2", "gene_name": "Lrtm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAPGGGPEQRSKLVLQWRQVSWITCWIALCAVEVIPACPFSCTCDSRSLEVDCSGLGLTTVPPDVPAATQSLLLLNNKLSALPSWAFANLSNLQRLDLSNNFLDQLPRSIFEDLVNLTELQLRNNSIRTLDRDLLQHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQSLDRLTFEPLASLQLLQVGDNPWECDCNLREFKHWLEWFSYRGGRLDQLACTLPKELRGKDMRAVPMEMFNYCSQLEDENNSAGLDAPGPPCTKASPEPPKPKPGAEPEPEPSTACPQKQRYRPVSVRRAIGTVIIAGVVCGIVCIMMVVAAAYGCIYASLMAKYHRELKKRQPLMGDPEGEHEDQKQISSVA", "length": 370 }, "evidence": [ { "id": "E1BKY5", "url": "https://omabrowser.org/oma/group/E1BKY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N967-1", "protein_name": "Leucine-rich repeat and transmembrane domain-containing protein 2", "gene_name": "LRTM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLAPGSSPGQRGRLALQWRQVSWITCWIALYAVEALPTCPFSCKCDSRSLEVDCSGLGLTTVPPDVPAATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPWECDCNLREFKHWMEWFSYRGGRLDQLACTLPKELRGKDMRMVPMEMFNYCSQLEDENSSAGLDIPGPPCTKASPEPAKPKPGAEPEPEPSTACPQKQRHRPASVRRAMGTVIIAGVVCGVVCIMMVVAAAYGCIYASLMAKYHRELKKRQPLMGDPEGEHEDQKQISSVA", "length": 370 }, "evidence": [ { "id": "E1BKY5", "url": "https://omabrowser.org/oma/group/E1BKY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BKY5", "url": "https://www.uniprot.org/uniprotkb/E1BKY5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "E1BKY5", "url": "https://www.uniprot.org/uniprotkb/E1BKY5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BKY5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 374, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BKY5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BKY5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BKY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKY5" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 202, "end_pos": 255, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BKY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKY5" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 76, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 129, "end_pos": 131 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BKY6-1", "uniprot_ac": "E1BKY6", "uniprot_id": "E1BKY6_BOVIN", "mass": { "chemical_mass": 28346.0, "monoisotopic_mass": 28346.0 }, "refseq": { "ac": "XP_002696691", "name": "duodenase-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696691" }, "gene_names": [ { "name": "LOC508858", "type": "recommended", "evidence": [ { "id": "E1BKY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKY6" } ] }, { "name": "LOC508858", "type": "synonym", "evidence": [ { "id": "XP_002696691", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696691" } ] } ], "protein_names": [ { "name": "Peptidase S1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "E1BKY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKY6/entry#names_and_taxonomy" } ] }, { "name": "duodenase-1", "type": "synonym", "evidence": [ { "id": "XP_002696691", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696691" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKY6", "url": "https://www.uniprot.org/uniprotkb/E1BKY6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC508858", "url": "https://www.uniprot.org/uniprotkb/E1BKY6", "locus": {} } ], "crossref": [ { "id": "E1BKY6", "url": "https://alphafold.ebi.ac.uk/entry/E1BKY6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000038080", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038080", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "508858", "url": "https://www.ncbi.nlm.nih.gov/gene/508858", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:508858", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508858", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NEMNICA", "url": "https://omabrowser.org/oma/group/NEMNICA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BKY6", "url": "https://www.orthodb.org/?gene=E1BKY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002696691", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696691", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BKY6", "url": "https://www.uniprot.org/uniprotkb/E1BKY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKY6-1", "url": "https://www.uniprot.org/uniprotkb/E1BKY6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLLLFLVALLFPTEEAGRIIGGHKAKPHSRPYMAFLQFKISGEPQRCGGFLVREDFVLTAAHCLGSSLSTSINVTLGAHNIKEREMTQQVIPVRRPIPHPDYNDETWANDIMLLKLMRKAHVTTTVSPISLPRDWDTVNPGMMCSVAGWGRRGVNMPSTDKLQEVDLEVRSEEECKDRFQDYNASIQICAGDPSKRKNSFSGDSGGPLVCNGVAQGIVSYGRDDGTTPDVYTRISSFLSWIHSTMRRYTRQGSA", "length": 255, "header": "tr|E1BKY6-1|E1BKY6_BOVIN Isoform 1 of Peptidase S1 domain-containing protein OS=Bos taurus OX=9913 GN=LOC508858 PE=4 SV=2 CANONICAL=E1BKY6-1" }, "isoforms": [ { "isoform_ac": "E1BKY6-1", "url": "https://www.uniprot.org/uniprotkb/E1BKY6/entry#E1BKY6-1", "sequence": { "sequence": "MVLLLFLVALLFPTEEAGRIIGGHKAKPHSRPYMAFLQFKISGEPQRCGGFLVREDFVLTAAHCLGSSLSTSINVTLGAHNIKEREMTQQVIPVRRPIPHPDYNDETWANDIMLLKLMRKAHVTTTVSPISLPRDWDTVNPGMMCSVAGWGRRGVNMPSTDKLQEVDLEVRSEEECKDRFQDYNASIQICAGDPSKRKNSFSGDSGGPLVCNGVAQGIVSYGRDDGTTPDVYTRISSFLSWIHSTMRRYTRQGSA", "length": 255, "header": "tr|E1BKY6-1|E1BKY6_BOVIN Isoform 1 of Peptidase S1 domain-containing protein OS=Bos taurus OX=9913 GN=LOC508858 PE=4 SV=2 CANONICAL=E1BKY6-1" }, 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"https://www.ncbi.nlm.nih.gov/gene/541059", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541059", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541059", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMQANYA", "url": "https://omabrowser.org/oma/group/IMQANYA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BL03", "url": "https://www.orthodb.org/?gene=E1BL03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31530", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31530", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31530:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31530:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22948", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22948", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015314718", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015314718", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BL03", "url": "https://www.uniprot.org/uniprotkb/E1BL03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL03-1", "url": "https://www.uniprot.org/uniprotkb/E1BL03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METNQETSLFLVKILEELDSKQNTVSYQDLCKSLCARFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCAVNNQQSKKIMVAADIVTIFNLIQMNGGAAKEKLPGGRQKMRKKDASFDSCRSDTEICSAAECEPLNCELSDRPFSRGYPTRQSSKCRKVDCKDCPQFIPASEPNFLLGVSKDVKNRAASLDRLQALAPYSVASPQPCEMQRTYFPMNLESESMSDQDSLPLPQGIKQTFISNDEPFVVQSCVQKRNIFKEDFHNLMAVSPGLASPANKAEGEHRKSQGRKESHKTPFPHHSFEMPYSSQYLNPEYSPVPDKRRAKHESLDDLQASTYFGPTPVMGPQEARRCPGKTGKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSNSQTPNFPTPDRCPAYLTPQDQQPILPVGYSAKPNGLKSKEIPSPVDLEKHEPVKKFKDKSISCTSGQLSSDTSSVGTQTDLHVLEPKKGKDLCTPGQGKYSDRHAVKHSDDDSEVVSDDISDIFRFLDDMSISGSTGVMQSSCYNSTGSLSQLHKSDCDSSPEHHLTRIANGLPSSQGEKGSRPENSHHSEEELKTSVCKLVLRIGEIERKLESLSGVREEISQVLGKLNKLDQKMQQPEKVSVQIDLNSLTSEAPSDESASPRMFRAHKGAHGPKLENTADWCCSDASGSNSESLRVQALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYSNRMGISEEEIKERGPGDSKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHPYPASLKAHMKSNPLYTDMRLTELAEVKRGQPSWTIEEYARNSGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPICTMKS", "length": 917, "header": "tr|E1BL03-1|E1BL03_BOVIN Isoform 1 of Membrane integral NOTCH2 associated receptor 1 OS=Bos taurus OX=9913 GN=MINAR1 PE=3 SV=1 CANONICAL=E1BL03-1" }, "isoforms": [ { "isoform_ac": "E1BL03-1", "url": "https://www.uniprot.org/uniprotkb/E1BL03/entry#E1BL03-1", "sequence": { "sequence": "METNQETSLFLVKILEELDSKQNTVSYQDLCKSLCARFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCAVNNQQSKKIMVAADIVTIFNLIQMNGGAAKEKLPGGRQKMRKKDASFDSCRSDTEICSAAECEPLNCELSDRPFSRGYPTRQSSKCRKVDCKDCPQFIPASEPNFLLGVSKDVKNRAASLDRLQALAPYSVASPQPCEMQRTYFPMNLESESMSDQDSLPLPQGIKQTFISNDEPFVVQSCVQKRNIFKEDFHNLMAVSPGLASPANKAEGEHRKSQGRKESHKTPFPHHSFEMPYSSQYLNPEYSPVPDKRRAKHESLDDLQASTYFGPTPVMGPQEARRCPGKTGKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSNSQTPNFPTPDRCPAYLTPQDQQPILPVGYSAKPNGLKSKEIPSPVDLEKHEPVKKFKDKSISCTSGQLSSDTSSVGTQTDLHVLEPKKGKDLCTPGQGKYSDRHAVKHSDDDSEVVSDDISDIFRFLDDMSISGSTGVMQSSCYNSTGSLSQLHKSDCDSSPEHHLTRIANGLPSSQGEKGSRPENSHHSEEELKTSVCKLVLRIGEIERKLESLSGVREEISQVLGKLNKLDQKMQQPEKVSVQIDLNSLTSEAPSDESASPRMFRAHKGAHGPKLENTADWCCSDASGSNSESLRVQALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYSNRMGISEEEIKERGPGDSKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHPYPASLKAHMKSNPLYTDMRLTELAEVKRGQPSWTIEEYARNSGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPICTMKS", "length": 917, "header": "tr|E1BL03-1|E1BL03_BOVIN Isoform 1 of Membrane integral NOTCH2 associated receptor 1 OS=Bos taurus OX=9913 GN=MINAR1 PE=3 SV=1 CANONICAL=E1BL03-1" }, "locus": { "chromosome": "21", "start_pos": 25623018, "end_pos": 25613353, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009330.5", "url": "https://www.ensembl.org/id/ENSBTAT00000009330.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009330.3", "url": "https://www.ensembl.org/id/ENSBTAP00000009330.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 343, "start_aa": "Thr", "end_pos": 343, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr343", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 407, "start_aa": "Thr", "end_pos": 407, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr407", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:541059", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541059", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HSZ1-1", "protein_name": "Major intrinsically disordered Notch2-binding receptor 1", "gene_name": "Minar1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEANQEASLFLVKILEELDSKQNTVSYQDLCKSLCAQFDLSQLTKLRSVLFYTACLDPNFPATLFKDKMKCSVNNQQSKKIMVAADIVTIFNLIQMNGGTAKEKLPTSCPKVRKKEASFESCRSDTEVCNPTVCEPLNCELGERPFSRGYPTRQSSKSRKRDCKECPQFVPASEPNFLLGVSKEVKNRAASLDRLQALSPYSMASPQPCEMQRTYFPMNIENESISDQDSLSISQGIKEPFISSEEPFVVQSCVQKRNIFKEEFHNLMTVSPSLVGPPNKTEGDRGETQNQKELHKTHFFNHSFEMPYHNQYLNPVYSPIPDKRRAKHESLDDLQASTYFGPTPVMGTQDARRCPGKSSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSGSQTPTFSGPDRHPTYLVPKDQQKVLPAGYAVKPNGLKSKEISSPVDLEKHEAVKKFKEKSISCTSGQHSSDTSSVGTQTEQHVLDAPKCKDLCTLGQAKYSDRHATMKHSDDDSEIVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLQKSDCDSSPEHNLAKITNGVTSSKGDKCNRPENVHHSEEELKTSVCKLVLRIGEIERKLESLSGVREEISQVLGKLNKLDQKIQQPEKVNVQIDLNSLTSEAPSDDSVSPRVFRAHSGSHGPKLENSPDWCCSDASGSNSESLRVKALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYTNRMSLNEEEIKDAGPGDNKDWHRKSKEADRQYDIPPQHRLPKQPKEGFLVEQVFSPHPYPASLKAHLKSNPLYTDMRLTELAEVKRGQPSWTIEEYARHSGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALITAAACTVILVIVVPICTMKS", "length": 918 }, "evidence": [ { "id": "E1BL03", "url": "https://omabrowser.org/oma/group/E1BL03/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1L4W4-1", "protein_name": "Membrane integral NOTCH2 associated receptor 1", "gene_name": "MINAR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METSQDTSLFLVKILEELDSKQNTVSYQDLCKSLCARFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCTVNNQQSKKIMVAADIVTIFNLIQMNGGAAKEKLPSGRQKARKKEASFDSCRSDTEICGAAECEALDCEMNDRPFSRGYPPRQSSKCRKMDCKDCPQFVPASEPNFLLGVSKEGKHRAASLDRLQALAPYSVASPQPCEMQRTYFPMNIENESMSDQDSLPLAQGIKETFIANEEPFVVQSCVQKRNIFKEDFHNLMAVSPGLAGPATKAEGEHGEPQGRKEAHKTPFPNHSFEMPYNSQYLNPVYSPVPDKRRAKHESLDDLQASTYFGPTPVMGTQEARRCPGRPSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSSSQTPSFPTPDRRPAYLTPQDQQPILPVGYAAKPNGLKSKEISSPVDLEKHEPVKKFKDKSISCTSGQLSSDTSSVGTQTEQHVLEPKKCKDLCASGQGKFSDRHTMKQSDDDSEVVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLHKSDCDSSPEHNRAKIANGLPSSKGEKGNRPENGHHSEEELKTSVCKLVLRIGEIERKLESLSGVREEISQVLGKLNKLDQKMQQPEKVSVQIDLNSLTSEAPSDESASPRMFRAHNGPHGPKLENSADWCCSDASGSNSESLRVQALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYPNRVGVGEEEIKDRGPGDSTDWHRKSKEADRQYDLPPQHRLPKQPQDGFLVEQVFSPHPYPASLKAHMKNNPLYTDMRLTELAEVKRGQPSWTIEEYARNAGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPICTMKS", "length": 917 }, "evidence": [ { "id": "E1BL03", "url": "https://omabrowser.org/oma/group/E1BL03/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZI84-1", "protein_name": "Membrane integral NOTCH2 associated receptor 1", "gene_name": "MINAR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MESNQETSLFLVKILEELDTKQNTVSYQDLCKSLCARFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMRCTVNNQQSKKIMVAADIVTIFNLIQMNGGVAKEKLPVARQKVKKKESFESCRSDTEICNMAECVPNCELSEQDFSQGFAVRRSSKCRKMDCKDCQQFVPSSEPNFLLGVNKEMKGRAASLDRLQALASYSIATSPPCEMQSTYFPMNIENESISDQDSLPISTGLKETFISNDEPFVMQSCVQKRNIFKEDFHNLITISPNLIPSNKKPEDGHREPQNRKESSKQTFFNHSFEMPYSSQYLNPVYSPIPDKRRVKHESLDDLQASTYFGPTTILGPQDTKKWTGKPTKQTAWPAKSWSLNTEEVPDFERSFFNRNQSEEKPRYQSSNNPSPNFPSADRHQSYLNPKDQQPIMQTNYAVKQNGHKPKEIPSILDVEKHEPVKKFKDKSINCTSVQILSIDRTMSVGTQTEQQVLDHKKCKDLCAPGQAKYAERHSLKHSDDDSEIVSDDISDIFRFLDDMSISGSTGVMQSSCYNSTGSLSQVHKSDCDSSPEHNLTKISNGSACNKLDKVVRADISNVDDELKTSVCKLVLRIGEIEKKLESLSGVREEISQVLGKLSKLDQKIQQPEKVSVQIDLNSLTSDAASDESNSPHIFQCHNTPHGGKLENNPEWCCSDASGSNSESLRVKALKKSLFTRRSSRSLTEENSATESKIASISNSPRDWRAITYTNKVGITEEEMKDRDGGENKDWHRKSKEADRQYEIPQPHRLPKQPKDAFLIEQVFSPHPYPASLKSHMKSNPLYTDMRLTELAEVKRAQPSWTIEEYTRNSGDKGKIAALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPICTMKS", "length": 916 }, "evidence": [ { "id": "E1BL03", "url": "https://omabrowser.org/oma/group/E1BL03/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZJ47-1", "protein_name": "Major intrinsically disordered Notch2-binding receptor 1", "gene_name": "Minar1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEANQEASLFLVKILEELDSKQNTVSYQDLCKSLCAQFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCSVNNQQSKKIMVAADIVTIFNLIQMNGGTAKEKLPTSCHKVRKEEASFESCRSDAEVCSPTVCEPLNCELSERPFSRGYPTRQSSKCRKMDCKECPQFVPASEPNFLLGVSKEVKNRAASLDRLQALSPYSVASPQPCEMQRTYFPMNIENESISDQDSLPIGQGIKETFISSEEPFMVQSCVQKRNIFKEDFHNLMTVSPSLVGTTNKAEEDHGEPRSQKELHKPPFFNHSFEMPYHSQYLNPVYSPIPDKRRAKHESLDDLQASTYFGPTPVMGTQDTRRCPGRPSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSGNQTPNFSGPDRHPVYLVPKDQQKVLPAGYAVKPNGLKSKEIPSPVDLEKHEAVKKFKDKSISCTSGQHSSDTSSVGTQTEQHVLDPPKCKDLCSAGQAKYSDRHAMKHSDDDSEIVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLHKSDCDSSPEHNLAKITNGVSGSKGDKCNRPENVHHSEEELKSSVCKLVLRIGEIERKLESLAGVREEISQVLGKLNKLDQKIQQPEKVNVQIDLNSLTSEAPSDDSASPRVFHAHSGSHGPKLENSPDWCCSDVSGSNSESLRVKALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYTNRMSLNEEEIKDAGPANNKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHPYPSSLKAHMKSNPLYTDMRLTELAEVKRGQPSWNIEEYARNTGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALITAAACTVILVIVVPICTMKS", "length": 917 }, "evidence": [ { "id": "E1BL03", "url": "https://omabrowser.org/oma/group/E1BL03/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K3V7-1", "protein_name": "Major intrinsically disordered Notch2-binding receptor 1", "gene_name": "Minar1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEANQEASLFLVKILEELDSKQNTVSYQDLCKSLCAQFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCSVNNQQSKKIMVAADIVTIFNLIQMNGGTAKEKLPMSCHKVRKKEASFESCRSDTEVCSPTVCEPLNCELSERPFSRGYPTRQSSKCRKMDCKECPQFVPASEPNFLLGVSKEVKNRAASLDRLQALSPYSVASPQPCEMQRTYFPMNIENEPMSDQDSLPISQGIKETFISSEEPFVVQSCVQKRNIFKEDFHNLMTVSPSLVGTTNKAEEGHGEPQSQKELHKPPFFNHSFEMPYHNQYLNPVYSPIPDKRRAKHESLDDLQASTYFGPTPVMGTQDTRRCPGRSSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSGSQTPNFSGPDRHPVYLVPKDQQKVLPAGYAVKPNGLKSKEISSPVDLEKHEAVKKFKDKSISCTSGQHSSDTSSVGTQTEQHVLDPPKCKDLCTSGQAKYGDRHAMKQSDDDSEIVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLHKSDCDSSPEHHLAKITNGVSSGKGDKCNRPENVHHSEEELKSSVCKLVLRIGEIERKLESLSGVREEISQVLGKLNKLDQKIQQPEKVNVQIDLNSLTSEAPSDDSASPRVFRAHSGSHGPKLENSPDWCCSDASGSNSESLRVKALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYTNRMSLNEEEIKDAGPANNKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHPYPTSLKGHMKSNPLYTDMRLTELAEVKRGQPSWTIEEYARNSGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALITAAACTVILVIVVPICTMKS", "length": 917 }, "evidence": [ { "id": "E1BL03", "url": "https://omabrowser.org/oma/group/E1BL03/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UPX6-1", "protein_name": "Major intrinsically disordered Notch2-binding receptor 1", "gene_name": "MINAR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METSQETSLFLVKILEELDSKQNTVSYQDLCKSLCARFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCTVNNQQSKKIMVAADIVTIFNLIQMNGGAAKEKLPTGRQKVRKKEASFESCRSDTEICNAAECEPLNCELSERSFSRGYPIRQSSKCRKMDCKDCPQFVPASEPNFLLGVSKEVKNRAASLDRLQALAPYSVTSPQPCEMQRTYFPMNIENESISDQDSLPINQSIKETFISNEEPFVVQSCVQKRNIFKEDFHNLMAVSPSLVGPISKAENEHREPQSRKEPHKPPFFNHSFEMPYNSQYLNPVYSPVPDKRRAKHESLDDLQASTYFGPTPVMGTQEARRCLGKPNKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLHYPNASSQTPNFPAPERRPTYLVPKDQQPILPIAYAAKQNGLKSKEISSPVDLEKHEPVKKFKDKSINCTSGQLSSDTSSVGTQTEHVLEPKKCRDLCTSGQGKYSDRHTMKHSDDDSEIVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLHKSDCDSSPEHNLTKIANGVPNSKGDKGNRPENTHHSEEELKTSVCKLVLRIGEIERKLESLSGVRDEISQVLGKLNKLDQKMQQPEKVSVQIDLNSLTSEGPSDDSASPRMFHAHSGSHGPKLENNPDWCCSDASGSNSESLRVKALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYTNRVGLNEEEIKDTGPGDNKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHPYPASLKAHMKSNPLYTDMRLTELAEVKRGQPSWTIEEYARNAGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPICTMKS", "length": 916 }, "evidence": [ { "id": "E1BL03", "url": "https://omabrowser.org/oma/group/E1BL03/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BL03", "url": "https://www.uniprot.org/uniprotkb/E1BL03" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "E1BL03", "url": "https://www.uniprot.org/uniprotkb/E1BL03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "E1BL03", "url": "https://www.uniprot.org/uniprotkb/E1BL03" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "E1BL03", "url": "https://www.uniprot.org/uniprotkb/E1BL03" } ], "pmid": "" }, { "name": "negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "E1BL03", "url": "https://www.uniprot.org/uniprotkb/E1BL03" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "E1BL03", "url": "https://www.uniprot.org/uniprotkb/E1BL03" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "E1BL03", "url": "https://www.uniprot.org/uniprotkb/E1BL03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BL03-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 917, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BL03-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BL03" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BL03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL03" }, { "id": "PF22948", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22948" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MINAR1 N-terminal helical", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 100, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BL03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL03" }, { "id": "PF06789", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06789" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major intrinsically disordered Notch2-binding receptor 1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 760, "end_pos": 915, "start_aa": "Asp", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 343, 407 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 544, "end_pos": 546 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BL07-1", "uniprot_ac": "E1BL07", "uniprot_id": "E1BL07_BOVIN", "mass": { "chemical_mass": 43167.0, "monoisotopic_mass": 43167.0 }, "refseq": { "ac": "NP_001179668", "name": "gastrin-releasing peptide receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179668" }, "gene_names": [ { "name": "GRPR", "type": "recommended", "evidence": [ { "id": "E1BL07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL07" } ] }, { "name": "GRPR", "type": "synonym", "evidence": [ { "id": "NP_001179668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179668" } ] } ], "protein_names": [ { "name": "Gastrin-releasing peptide receptor", "type": "recommended", "evidence": [ { "id": "E1BL07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL07/entry#names_and_taxonomy" } ] }, { "name": "GRP-preferring bombesin receptor", "type": "synonym", "evidence": [ { "id": "E1BL07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL07/entry#names_and_taxonomy" } ] }, { "name": "gastrin-releasing peptide receptor", "type": "synonym", "evidence": [ { "id": "NP_001179668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179668" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BL07", "url": "https://www.uniprot.org/uniprotkb/E1BL07" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GRPR", "url": "https://www.uniprot.org/uniprotkb/E1BL07", "locus": { "chromosome": "X", "start_pos": 127346064, "end_pos": 127383270, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007092", "url": "https://www.ensembl.org/id/ENSBTAG00000007092" } ] } } ], "crossref": [ { "id": "E1BL07", "url": "https://alphafold.ebi.ac.uk/entry/E1BL07", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007092", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007092", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15124", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15124", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532784", "url": "https://www.ncbi.nlm.nih.gov/gene/532784", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001556", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001556", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532784", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532784", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HAFTTSH", "url": "https://omabrowser.org/oma/group/HAFTTSH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BL07", "url": "https://www.orthodb.org/?gene=E1BL07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179668", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BL07", "url": "https://www.uniprot.org/uniprotkb/E1BL07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL07-1", "url": "https://www.uniprot.org/uniprotkb/E1BL07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALNDCLLLNLEVDHFVHCNISNHSVELPMNDDWFHPGILYVIPAIYGVIILIGLVGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASRYLADKWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALLKICLKAALIWIVSMLLAIPEAVFSDLHPFHEESTNRTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHIIYLYRSYHYSEVDTSMLHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCRPGLMSRSHSAGRSTSCMTSFKSTNPSAATFSLINGNICHEGYV", "length": 384, "header": "tr|E1BL07-1|E1BL07_BOVIN Isoform 1 of Gastrin-releasing peptide receptor OS=Bos taurus OX=9913 GN=GRPR PE=3 SV=1 CANONICAL=E1BL07-1" }, "isoforms": [ { "isoform_ac": "E1BL07-1", "url": "https://www.uniprot.org/uniprotkb/E1BL07/entry#E1BL07-1", "sequence": { "sequence": "MALNDCLLLNLEVDHFVHCNISNHSVELPMNDDWFHPGILYVIPAIYGVIILIGLVGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASRYLADKWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALLKICLKAALIWIVSMLLAIPEAVFSDLHPFHEESTNRTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHIIYLYRSYHYSEVDTSMLHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCRPGLMSRSHSAGRSTSCMTSFKSTNPSAATFSLINGNICHEGYV", "length": 384, "header": "tr|E1BL07-1|E1BL07_BOVIN Isoform 1 of Gastrin-releasing peptide receptor OS=Bos taurus OX=9913 GN=GRPR PE=3 SV=1 CANONICAL=E1BL07-1" }, "locus": { "chromosome": "X", "start_pos": 127383270, "end_pos": 127346210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009328.4", "url": "https://www.ensembl.org/id/ENSBTAT00000009328.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009328.2", "url": "https://www.ensembl.org/id/ENSBTAP00000009328.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532784", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532784", "resource": "KEGG Pathway" }, { "id": "R-BTA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-BTA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F6G4-1", "protein_name": "Gastrin-releasing peptide receptor", "gene_name": "grpr", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDATLTPVVKFLGDSPERSNTSAVPEHPHLHSGIIIATVYALLITAGLIGNVTLIRTFCIVKSMRNVPNLFMSSLALGDVLLLVTCAPVDASKFLADEWLFGRMGCKLIPFIQLTSVGVSVFTLTALAADRYKAIVKPMDIQSSKASLKVCLRAASIWMLSMVLAIPEAVFSDLHTFHIPQTNETFKTCAPYPHAGDLHPKIHSMASFLILYIIPLFIISVYYIFIARSLIQSANNMPVEGNTHIRRQVESRMRLAKTVLVFVGLFAICWLPNHVIYLYRSYHYTEVDTSMAHFIASVCARILAFTNSCVNPFALYLLSKSFRKQFNKQLCCCCPSISLRSQSSRRHNTRLSSLKSTQNHSVASFSLVNGNAVYH", "length": 376 }, "evidence": [ { "id": "E1BL07", "url": "https://omabrowser.org/oma/group/E1BL07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HXH5-1", "protein_name": "Gastrin-releasing peptide receptor", "gene_name": "Grpr", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALNNCSHLDLEVDPFLHCNNTFNQSLNPPKMDNWFHPGIIYVIPAVYGVIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRMGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLMSRSHSTGRSTTCMTSFKSTNPSATFSLINGNIYHEGYV", "length": 384 }, "evidence": [ { "id": "E1BL07", "url": "https://omabrowser.org/oma/group/E1BL07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P21729-1", "protein_name": "Gastrin-releasing peptide receptor", "gene_name": "Grpr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPNNCSHLNLDVDPFLSCNDTFNQSLSPPKMDNWFHPGFIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLAIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLMNRSHSTGRSTTCMTSFKSTNPSATFSLINRNICHEGYV", "length": 384 }, "evidence": [ { "id": "E1BL07", "url": "https://omabrowser.org/oma/group/E1BL07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P30550-1", "protein_name": "Gastrin-releasing peptide receptor", "gene_name": "GRPR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALNDCFLLNLEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTSLKSTNPSVATFSLINGNICHERYV", "length": 384 }, "evidence": [ { "id": "E1BL07", "url": "https://omabrowser.org/oma/group/E1BL07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P52500-1", "protein_name": "Gastrin-releasing peptide receptor", "gene_name": "Grpr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPNNCSHLNLEVDPFLSCNNTFNQTLNPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMTSFKSTNPSATFSLINGNICHEGYV", "length": 384 }, "evidence": [ { "id": "E1BL07", "url": "https://omabrowser.org/oma/group/E1BL07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4V622-1", "protein_name": "Neuropeptide CCHamide-2 receptor", "gene_name": "CCHa2-R", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYASLMDVGQTLAARLADSDGNGANDSGLLATGQGLEQEQEGLALDMGHNASADGGIVPYVPVLDRPETYIVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESWPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAVMIWILAILLGMPSVLFSDIKSYPVFTATGNMTIEVCSPFRDPEYAKFMVAGKALVYYLLPLSIIGALYIMMAKRLHMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHFYPTAEEDFDEFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRYLCCICVKRQPHLRQHSTATGMMDNTSVMSMRRSTYVGGTAGNLRASLHRNSNHGVGGAGGGVGGGVGSGRVGSFHRQDSMPLQHGNAHGGGAGGGSSGLGAGGRTAAVSEKSFINRYESGVMRY", "length": 489 }, "evidence": [ { "id": "E1BL07", "url": "https://omabrowser.org/oma/group/E1BL07/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BL07", "url": "https://www.uniprot.org/uniprotkb/E1BL07" } ], "pmid": "" } ] 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{ "uniprot_canonical_ac": "E1BL13-1", "uniprot_ac": "E1BL13", "uniprot_id": "E1BL13_BOVIN", "mass": { "chemical_mass": 35644.0, "monoisotopic_mass": 35644.0 }, "refseq": { "ac": "NP_001376850", "name": "olfactory receptor 4E2", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376850" }, "gene_names": [ { "name": "OR4E2", "type": "recommended", "evidence": [ { "id": "E1BL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL13" } ] }, { "name": "OR4E2", "type": "synonym", "evidence": [ { "id": "NP_001376850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376850" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL13/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4E2", "type": "synonym", "evidence": [ { "id": "NP_001376850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376850" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376850", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376850" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BL13", "url": "https://www.uniprot.org/uniprotkb/E1BL13#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BL13", "url": "https://www.uniprot.org/uniprotkb/E1BL13" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4E2", "url": "https://www.uniprot.org/uniprotkb/E1BL13", "locus": { "chromosome": "10", "start_pos": 25539229, "end_pos": 25540170, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007029", "url": "https://www.ensembl.org/id/ENSBTAG00000007029" } ] } } ], "crossref": [ { "id": "E1BL13", "url": "https://alphafold.ebi.ac.uk/entry/E1BL13", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15940", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15940", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513435", "url": "https://www.ncbi.nlm.nih.gov/gene/513435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513435", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513435", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CACAEIF", "url": "https://omabrowser.org/oma/group/CACAEIF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BL13", "url": "https://www.orthodb.org/?gene=E1BL13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376850", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376850", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BL13", "url": "https://www.uniprot.org/uniprotkb/E1BL13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL13-1", "url": "https://www.uniprot.org/uniprotkb/E1BL13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDALNQTRVTQFVFLGLTDNWVLEILFFMAFSVMYVLTLLGNILIMVTIVFTPRLHIPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCIAQLFFLHLFACAEIFLLTVMAYDRYVAICVPLHYPNVMDMRVCVQLVFALWLGGTIHSLVQTFLTIRLPYCGPNVIDSYFCDVPPVIKLACTDTYLTGMLIVSNSGTISLFCFLALVTSYMVILVSLRKQSAEGRRKALSTCSAHFMVVALFFGPCIFLYTHPDTNFSSDKVVSVFYTMVTPVLNPLIYTLRNEEVKNAMKRLRQRQVFSMKSCT", "length": 313, "header": "tr|E1BL13-1|E1BL13_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4E2 PE=3 SV=2 CANONICAL=E1BL13-1" }, "isoforms": [ { "isoform_ac": "E1BL13-1", "url": "https://www.uniprot.org/uniprotkb/E1BL13/entry#E1BL13-1", "sequence": { "sequence": "MDALNQTRVTQFVFLGLTDNWVLEILFFMAFSVMYVLTLLGNILIMVTIVFTPRLHIPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCIAQLFFLHLFACAEIFLLTVMAYDRYVAICVPLHYPNVMDMRVCVQLVFALWLGGTIHSLVQTFLTIRLPYCGPNVIDSYFCDVPPVIKLACTDTYLTGMLIVSNSGTISLFCFLALVTSYMVILVSLRKQSAEGRRKALSTCSAHFMVVALFFGPCIFLYTHPDTNFSSDKVVSVFYTMVTPVLNPLIYTLRNEEVKNAMKRLRQRQVFSMKSCT", "length": 313, "header": "tr|E1BL13-1|E1BL13_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4E2 PE=3 SV=2 CANONICAL=E1BL13-1" }, "locus": { "chromosome": "10", "start_pos": 25540170, "end_pos": 25539232, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056770.3", "url": "https://www.ensembl.org/id/ENSBTAT00000056770.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050397.2", "url": "https://www.ensembl.org/id/ENSBTAP00000050397.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:513435", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513435", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UZX8-1", "protein_name": "Olfactory receptor", "gene_name": "OR4E2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDALNQTRVTEFVFLGLTDNWVLEILLFMAFSVMYVLTLLGNVLIMATIVFTPRLHTPMYFFLSNLSFIDICHSSVTMPKMLEGLLSERKTISFDNCIAQLFFLHLFACAEIFLLTIMAYDRYVAICAPLHYPNVINMKVCVQLVFALWLGGTVHSLVQTFLTIRLPYCGPNVIDSYFCDVPPVITLACTDTHLTGMLIVSNSGTISLVCFLALVTSYMVILVSLRRQSAEGRRKALSTCSAHLMVVALFFGPCIFIYTRPDTSFSIDKVVSVFYTVVTPVLNPLIYTLRNEEVKIAMKHLRQGQVFFMKSCT", "length": 313 }, "evidence": [ { "id": "E1BL13", "url": "https://omabrowser.org/oma/group/E1BL13/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4ADC0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4e2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGALNQTRVTEFVFLGLTDNWVLEILFFIPFTVTYVLTLLGNVLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLVRKTISFDNCIAQLFFLHLFACAEIFLLTIMAYDRYVAICIPLHYPNVMNMKVCVQLVFALWLGGTVHSLVQTFLTIRLPYCGPNTIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTSYTVILFSLRKQSAEGRRKALSTCSAHFMVVALFFGPCIFIYTWPDTSFSIDKVVSVFYTVVTPLLNPLIYTLRNEEVKTSMKHLRQRRICS", "length": 308 }, "evidence": [ { "id": "E1BL13", "url": "https://omabrowser.org/oma/group/E1BL13/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HWR6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100773156", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGALNQTRVTEFVFLGLTDNWVLEILFFIPFTVTYVLTLLGNILIVVTIVFSPRLHTPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCIAQLFFLHLFACAEIFLLTIMAYDRYVAICIPLHYPSVMNMRVCVQLVFALWVGGTVHSLVQTFLTIRLPYCGPNIIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLTCFLALVTSYTVILFSLRKQSAEGRRKALSTCSSHFMVVALFFGPCIFIYTRPDTSFSIDKVVSVFYTVVTPLLNPLIYTLRNEEVKNAMKQLRQRQICS", "length": 308 }, 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"IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540628", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540628", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ASYSMSY", "url": "https://omabrowser.org/oma/group/ASYSMSY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BL43", "url": "https://www.orthodb.org/?gene=E1BL43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45793:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45793:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192946", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192946", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BL43", "url": "https://www.uniprot.org/uniprotkb/E1BL43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL43-1", "url": "https://www.uniprot.org/uniprotkb/E1BL43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSASANPAAAAAAGLGGNPAVAVPSSLSTPAASSIWSPASISPGSAPASVSMPEPLAAPSNASCMQRSVAAGAASAAASYPMSYGQGGSYGQGYPAPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMASHHHHHPHAHHPLSQSSGHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL", "length": 355, "header": "tr|E1BL43-1|E1BL43_BOVIN Isoform 1 of Orthodenticle homeobox 1 OS=Bos taurus OX=9913 GN=OTX1 PE=3 SV=1 CANONICAL=E1BL43-1" }, "isoforms": [ { "isoform_ac": "E1BL43-1", "url": "https://www.uniprot.org/uniprotkb/E1BL43/entry#E1BL43-1", "sequence": { "sequence": "MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSASANPAAAAAAGLGGNPAVAVPSSLSTPAASSIWSPASISPGSAPASVSMPEPLAAPSNASCMQRSVAAGAASAAASYPMSYGQGGSYGQGYPAPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMASHHHHHPHAHHPLSQSSGHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL", "length": 355, "header": "tr|E1BL43-1|E1BL43_BOVIN Isoform 1 of Orthodenticle homeobox 1 OS=Bos taurus OX=9913 GN=OTX1 PE=3 SV=1 CANONICAL=E1BL43-1" }, "locus": { "chromosome": "11", "start_pos": 61550146, "end_pos": 61546879, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008893.4", "url": "https://www.ensembl.org/id/ENSBTAT00000008893.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008893.2", "url": "https://www.ensembl.org/id/ENSBTAP00000008893.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540628", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540628", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ARL1-1", "protein_name": "Orthodenticle homeobox 1", "gene_name": "OTX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSASANPAAAAAAGLGGNPAVAVPSSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSNASCMQRSVAAGAASAAASYPMSYGQGGSYGQGYPAPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMASHHHHHPHAHHPLSQSSGHHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL", "length": 356 }, "evidence": [ { "id": "E1BL43", "url": "https://omabrowser.org/oma/group/E1BL43/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YWZ7-1", "protein_name": "Orthodenticle homeobox 1", "gene_name": "OTX1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMSYLKQPPYGMNGLGLPGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGGGAKSRPAKKKSSPARESSGSESSGQFTPPAAASSSSASSSSSSSASSGAAAAAAGAAPASLGTTASSIWSPASISPGAAPAGVTVPEPLPPAGASCMQRAGPAASASYPVSYGQGGGYGQGYPAPPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMGPSSVPGHHHHHPLSQSSGHHHHHHHHHHQGYGGTALPFNSSDCLDYKEPAAAASWKLNFNSPDCLDYKDQASWRFQVL", "length": 335 }, "evidence": [ { "id": "E1BL43", "url": "https://omabrowser.org/oma/group/E1BL43/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P32242-1", "protein_name": "Homeobox protein OTX1", "gene_name": "OTX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL", "length": 354 }, "evidence": [ { "id": "E1BL43", "url": "https://omabrowser.org/oma/group/E1BL43/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P80205-1", "protein_name": "Homeobox protein OTX1", "gene_name": "Otx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGNGTKTRPVKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSASANPAAAAAAGLGGNPVAAASSLSTPTASSIWSPASISPGSAPTSVSVPEPLAAPSNASCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPAPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPAAAAASSAWKLNFNSPDCLDYKDQASWRFQVL", "length": 355 }, "evidence": [ { "id": "E1BL43", "url": "https://omabrowser.org/oma/group/E1BL43/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63410-1", "protein_name": "Homeobox protein OTX1", "gene_name": "Otx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGNGTKSRPVKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSASANPAAAAAAGLGGNPVAAASSLSTPTASSIWSPASISPGSAPASVSVPEPLGAPSNASCMQRSVAAGAATAATSYPMSYGQGRSYGQGYPAPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPAAAAASSAWKLNFNSPDCLDYKDQASWRFQVL", "length": 355 }, "evidence": [ { "id": "E1BL43", "url": "https://omabrowser.org/oma/group/E1BL43/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91994-1", "protein_name": "Homeobox protein OTX1 B", "gene_name": "otx1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSYLKQPPYAMNGLGLSGAAMDLLHPSVGYPATPRKQRRERTTFTRSQLDILEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSSTKTRPAKKKSSPTRESTGSESSGQFTPPAVSSAGSSSSSSSSTNNTGISSTSTSISTVSSIWSPAISPGSAPPSVSLPEPVAPSNTSCMQRSVSGTASSTYPMPYNQTTGYSQGYPTPSGSYFSGVDCGSYLAPMHSHHHPHQLSPMTASSMPTHPHHHISQSSGHHHHHHHQAYSGTGLAFNSSDCLDYKEQTASSWKLNFNTTDCLDYKDQASWRFQVL", "length": 323 }, "evidence": [ { "id": "E1BL43", "url": "https://omabrowser.org/oma/group/E1BL43/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BL43", "url": "https://www.uniprot.org/uniprotkb/E1BL43" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BL43", "url": "https://www.uniprot.org/uniprotkb/E1BL43" } ], "pmid": "" }, { "name": "midbrain development", "id": "GO:0030901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030901", "evidence": [ { "database": "UniProtKB", "id": "E1BL43", "url": "https://www.uniprot.org/uniprotkb/E1BL43" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BL43", "url": "https://www.uniprot.org/uniprotkb/E1BL43" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BL43", "url": "https://www.uniprot.org/uniprotkb/E1BL43" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BL43", "url": "https://www.uniprot.org/uniprotkb/E1BL43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BL43-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 355, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BL43-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BL43" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BL43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL43" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000256", "start_pos": 38, "end_pos": 97, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 171 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377161" }, "gene_names": [ { "name": "OR8A1E", "type": "recommended", "evidence": [ { "id": "E1BL96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL96" } ] }, { "name": "OR8A1E", "type": "synonym", "evidence": [ { "id": "NP_001377161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377161" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BL96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL96/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8A1", "type": "synonym", "evidence": [ { "id": "NP_001377161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377161" } ] }, { "name": "olfactory receptor family 8 subfamily A member 1E", "type": "synonym", "evidence": [ { "id": "NP_001377161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377161" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377161", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377161" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BL96", "url": "https://www.uniprot.org/uniprotkb/E1BL96#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BL96", "url": "https://www.uniprot.org/uniprotkb/E1BL96" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8A1E", "url": "https://www.uniprot.org/uniprotkb/E1BL96", "locus": { "chromosome": "29", "start_pos": 27961826, "end_pos": 27960897, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000057091", "url": "https://www.ensembl.org/id/ENSBTAG00000057091" } ] } } ], "crossref": [ { "id": "E1BL96", "url": "https://alphafold.ebi.ac.uk/entry/E1BL96", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000051944", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000051944", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617011", "url": "https://www.ncbi.nlm.nih.gov/gene/617011", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617011", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617011", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEILPMM", "url": "https://omabrowser.org/oma/group/CEILPMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BL96", "url": "https://www.orthodb.org/?gene=E1BL96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377161", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377161", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BL96", "url": "https://www.uniprot.org/uniprotkb/E1BL96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL96-1", "url": "https://www.uniprot.org/uniprotkb/E1BL96-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTENHSTVTEFILQGLTERPELQLPLLFLFLGIYLVTMIGNLGMITLICLNAQLHTPMYYFLSNLSFVDLCYSSVITPKMLVNFVSGKNIISYAGCMAQLYFFLVFVIAECYMLTVMAYDRYVAICRPLFYNIIMSHRVCSLLMVGVYAMGFIGSTIETGLMLKQSYCEGLISYYFCEILPMMKLTCSSTYHVEMTVFLLAGFNIIVTSLTVLISYAFILSSILHISTTGGRAKAFSTCSSHLAAVGMFYGTTAFMYLKPSTASSLAQENVASVFYTTVIPMLNPLIYSLRNKEVKAAMQKTLRGKQF", "length": 309, "header": "tr|E1BL96-1|E1BL96_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR8A1E PE=3 SV=3 CANONICAL=E1BL96-1" }, "isoforms": [ { "isoform_ac": "E1BL96-1", "url": "https://www.uniprot.org/uniprotkb/E1BL96/entry#E1BL96-1", "sequence": { "sequence": "MVTENHSTVTEFILQGLTERPELQLPLLFLFLGIYLVTMIGNLGMITLICLNAQLHTPMYYFLSNLSFVDLCYSSVITPKMLVNFVSGKNIISYAGCMAQLYFFLVFVIAECYMLTVMAYDRYVAICRPLFYNIIMSHRVCSLLMVGVYAMGFIGSTIETGLMLKQSYCEGLISYYFCEILPMMKLTCSSTYHVEMTVFLLAGFNIIVTSLTVLISYAFILSSILHISTTGGRAKAFSTCSSHLAAVGMFYGTTAFMYLKPSTASSLAQENVASVFYTTVIPMLNPLIYSLRNKEVKAAMQKTLRGKQF", "length": 309, "header": "tr|E1BL96-1|E1BL96_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR8A1E PE=3 SV=3 CANONICAL=E1BL96-1" }, "locus": { "chromosome": "29", "start_pos": 27961823, "end_pos": 27960897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030288.5", "url": "https://www.ensembl.org/id/ENSBTAT00000030288.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030272.5", "url": "https://www.ensembl.org/id/ENSBTAP00000030272.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617011", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617011", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BL96", "url": "https://www.uniprot.org/uniprotkb/E1BL96" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "E1BL96", "url": "https://www.uniprot.org/uniprotkb/E1BL96" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "E1BL96", "url": "https://www.uniprot.org/uniprotkb/E1BL96" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BL96", "url": "https://www.uniprot.org/uniprotkb/E1BL96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "E1BL96", "url": "https://www.uniprot.org/uniprotkb/E1BL96" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "E1BL96", "url": "https://www.uniprot.org/uniprotkb/E1BL96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BL96-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BL96-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BL96" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BL96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL96" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NLU1-1", "uniprot_ac": "A0ABI0NLU1", "uniprot_id": "A0ABI0NLU1_BOVIN", "mass": { "chemical_mass": 52408.0, "monoisotopic_mass": 52408.0 }, "refseq": { "ac": "XP_010816520", "name": "transcription factor AP-2-beta isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816520" }, "gene_names": [ { "name": "TFAP2B", "type": "recommended", "evidence": [ { "id": "A0ABI0NLU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1" } ] }, { "name": "TFAP2B", "type": "synonym", "evidence": [ { "id": "XP_010816520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816520" } ] } ], "protein_names": [ { "name": "Transcription factor AP-2 beta", "type": "synonym", "evidence": [ { "id": "A0ABI0NLU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1/entry#names_and_taxonomy" } ] }, { "name": "transcription factor AP-2-beta isoform X3", "type": "synonym", "evidence": [ { "id": "XP_010816520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816520" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TFAP2B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1", "locus": { "chromosome": "23", "start_pos": 23401373, "end_pos": 23375242, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020426", "url": "https://www.ensembl.org/id/ENSBTAG00000020426" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020426", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020426", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540867", "url": "https://www.ncbi.nlm.nih.gov/gene/540867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LLF9", "url": "https://www.orthodb.org/?gene=A0A3Q1LLF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MIT9", "url": "https://www.orthodb.org/?gene=A0A3Q1MIT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10812", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10812", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10812:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10812:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10812:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10812:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03299", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03299", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010816520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816520", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLF9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIT9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLU1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHSPPRDQAAIMLWKLVENVKYEDIYEMLVHTYSSMDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLHQPQQHPWGQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVPPKSVTSLMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTTNRHTSGEGPALPAWFMSFFKEDLGFLHNL", "length": 476, "header": "tr|A0ABI0NLU1-1|A0ABI0NLU1_BOVIN Isoform 1 of Transcription factor AP-2 beta OS=Bos taurus OX=9913 GN=TFAP2B PE=3 SV=1 CANONICAL=A0ABI0NLU1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLF9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1/entry#A0A3Q1LLF9-1", "sequence": { "sequence": "MLVQWDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLHQPQQHPWGQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVPPKSVTSLMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTTNRHTSGEGPGSKTGDKEEKHRK", "length": 438, "header": "tr|A0A3Q1LLF9-1|A0ABI0NLU1_BOVIN Computationally mapped isoform of Transcription factor AP-2 beta OS=Bos taurus OX=9913 GN=TFAP2B PE=3 SV=2 CANONICAL=A0ABI0NLU1-1" }, "locus": { "chromosome": "23", "start_pos": 23400369, "end_pos": 23379914, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082068.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082068.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057393.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057393.2" } ] } }, { "isoform_ac": "A0A3Q1MIT9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1/entry#A0A3Q1MIT9-1", "sequence": { "sequence": "MHSPPRDQAAIMLWKLVENVKYEDIYEMLVHTYSSMDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLHQPQQHPWGQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVPPKSVTSLMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTTNRHTSGEGPGSKTGDKEEKHRK", "length": 469, "header": "tr|A0A3Q1MIT9-1|A0ABI0NLU1_BOVIN Computationally mapped isoform of Transcription factor AP-2 beta OS=Bos taurus OX=9913 GN=TFAP2B PE=3 SV=2 CANONICAL=A0ABI0NLU1-1" }, "locus": { "chromosome": "23", "start_pos": 23400369, "end_pos": 23375799, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081686.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081686.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071222.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071222.2" } ] } }, { "isoform_ac": "A0ABI0NLU1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1/entry#A0ABI0NLU1-1", "sequence": { "sequence": "MHSPPRDQAAIMLWKLVENVKYEDIYEMLVHTYSSMDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLHQPQQHPWGQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVPPKSVTSLMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTTNRHTSGEGPALPAWFMSFFKEDLGFLHNL", "length": 476, "header": "tr|A0ABI0NLU1-1|A0ABI0NLU1_BOVIN Isoform 1 of Transcription factor AP-2 beta OS=Bos taurus OX=9913 GN=TFAP2B PE=3 SV=1 CANONICAL=A0ABI0NLU1-1" }, "locus": { "chromosome": "23", "start_pos": 23401444, "end_pos": 23375799, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146005.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146005.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105855.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105855.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NLU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLU1" }, { "id": "PF03299", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03299" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transcription factor AP-2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 239, "end_pos": 433, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 443, "end_pos": 445 }, { "start_pos": 444, "end_pos": 446 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NKD4-1", "uniprot_ac": "A0ABI0NKD4", "uniprot_id": "A0ABI0NKD4_BOVIN", "mass": { "chemical_mass": 154329.0, "monoisotopic_mass": 154329.0 }, "refseq": { "ac": "XP_005201497", "name": "protein HEG homolog 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005201497" }, "gene_names": [ { "name": "HEG1", "type": "recommended", "evidence": [ { "id": "A0ABI0NKD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4" } ] }, { "name": "HEG1", "type": "synonym", "evidence": [ { "id": "XP_005201497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005201497" } ] } ], "protein_names": [ { "name": "Heart development protein with EGF like domains 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NKD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4/entry#names_and_taxonomy" } ] }, { "name": "protein HEG homolog 1", "type": "synonym", "evidence": [ { "id": "XP_005201497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005201497" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HEG1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4", "locus": { "chromosome": "1", "start_pos": 69421853, "end_pos": 69501770, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021396", "url": "https://www.ensembl.org/id/ENSBTAG00000021396" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021396", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021396", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "511689", "url": "https://www.ncbi.nlm.nih.gov/gene/511689", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511689", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511689", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MIM0", "url": "https://www.orthodb.org/?gene=A0A3Q1MIM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24037:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24037:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005201497", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005201497", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIM0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKD4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZK9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZK9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPPLLLLLLPLLLLPPPAAPGTRGQPFSPAGAGPAWPTESSPGLKLPPSPTSPPERRGPASPGHRQTAPAPGAARRPGPSSRAPRSGSAAVVKNHWLESNTEPQIENITFDQNQVDFSTVVSKEGVMVQTPRKIHPSLDAPENITLQTETAAARGINDSSGRTEFTVPHYGPGRTTTLTSQSSTLALGKRHPPSSSSGSEARTAPLYMESGTSWGSPAGAQGLPEEVTVHTQMAATSVLSQSSLPAVEGGEETALPRQRSSSGPEPSWPPLSRTSAYSPPSDHPSSSGSTEDLNNSTAVHSSSVSGTESVHVATTFPNSVQRTPQSSATSLRPLNETEHFPEDSEIAITSSSVHSSPSEAELRRSSGVFGSPGNGAFTELSTEIAFGPTSSNISREFWQNDSPTSGGPQLASGSGAGNGSPVSQTETSSRSIPPVRGEESTALWFSTGSEPFAGAAGSSTSHPEVVNASVLTRFSASAPQSQGSDPALYEMSYSELATEALSSSSSESLGFSAPRGERSTTEDSPELGAGTKAEEGASWGVPGVRTHSPHTLATFAGVGERTLRSLTNRSTTSGDVERSMATTGEMESATQQGNMTVTGDARPVSGSLAATRTFGGHGVTGISYDGASSTDPDCRTSSEHTNYTCASSPFTKGERTLLSITDNSSSWDGRETSTSSVKISSSLSSDSSPSSQAQTERSNVSSHQGEHAQPSTGALVLSTASSPSHTPTLNTLTTLVPRDTDAKSVGGALSSSSSEPPLPLPSVSQSYQFSSTLPSAGASTHRLQSSPDAPTPLSSSPPPSSVSLTASAPASLSDSQTALPHAPFTPVLPRTRDAPVTSVRMSAVASSIPSSQTADPPKNQSSPYLKNTVTESKPPSLQTLPAEATKAVTVMSTLGIPSPRPFTDYSTSTDTEQTLPATSTDLAHTSPALAATTPETSHSPVASPSLQSSTAALTGGPTTGQTVARETEQTVVQLSPTSPEILVVQVTTEGAVTTEESPVDRDAATRLFPLTKESTTGPGPIEDNSLASPFLKTSPSPRTTPVSTAKVLTPPSTTSTVRSSTRSPTAPSSPAAVNSCTTHPCLHDGKCVVDLTTHPGYRCVCSPAWQGDNCSVDVNECLSNPCPPLATCNNTQGSFTCRCPVGYQLEKGICNLVRTFVTEFKLKKTFLNTTVEKHSDLREVENEITKMLNVCFSTLPGYTRSTAHVSRESSVVVMSLQATFSLASNVTLFDLADRMQKCVNSCWASAEVCQLLGSQRRIFRAGSLCKRKTPECDKETSICTDLDGVALCQCKSGYFQFNKMDHSCRACEDGYRLENETCMSCPFGLGGLNCGNPYQLITVVIAAAGGGLLLILGIALIVTCCRKNKNDISKLIFKSGDFQMSPYAEYPKNPRSQEWGREAIEMHENGSTKNLLQMTDVYYSPSSVRNPELERNGLYPAYTGLPGSRHSCIFPGQYNPSFISDESRRRDYF", "length": 1471, "header": "tr|A0ABI0NKD4-1|A0ABI0NKD4_BOVIN Isoform 1 of Heart development protein with EGF like domains 1 OS=Bos taurus OX=9913 GN=HEG1 PE=4 SV=1 CANONICAL=A0ABI0NKD4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MIM0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4/entry#A0A3Q1MIM0-1", "sequence": { "sequence": "MASPPLLLLLLPLLLLPPPAAPGTRGQPFSPAGAGPAWPTESSPGLKLPPSPTSPPERRGPASPGHRQTAPAPGAARRPGPSSRAPRSGSAAVVKNHWLESNTEPQIENITFDQNQVDFSTVVSKEGVMVQTPRKIHPSLDAPENITLQTETAAARGINDSSGRTEFTVPHYGPGRTTTLTSQSSTLALGKRHPPSSSSGSEARTAPLYMESGTSWGSPAGAQGLPEEVTVHTQMAATSVLSQSSLPAVEGGEETALPRQRSSSGPEPSWPPLSRTSAYSPPSDHPSSSGSTEDLNNSTAVHSSSVSGTESVHVATTFPNSVQRTPQSSATSLRPLNETEHFPEDSEIAITSSSVHSSPSEAELRRSSGVFGSPGNGAFTELSTEIAFGPTSSNISREFWQNDSPTTEDSPELGAGTKAEEGASWGVPGVRTHSPHTLATFAGVGERTLRSLTNRSTTSGDVERSMATTGEMESATQQGNMTVTGDARPVSGSLAATRTFGGHGVTGISYDGASSTDPDCRTSSEHTNYTCASSPFTKGERTLLSITDNSSSWDGRETSTSSVKISSSLSSDSSPSSQAQTERSNVSSHQGEHAQPSTGALVLSTASSPSHTPTLNTLTTLVPRDTDAKSVGGALSSSSSEPPLPLPSVSQSYQFSSTLPSAGASTHRLQSSPDAPTPLSSSPPPSSVSLTASAPASLSDSQTALPHAPFTPVLPRTRDAPVTSVRMSAVASSIPSSQTADPPKNQSSPYLKNTVTESKPPSLQTLPAEATKAVTVMSTLGIPSPRPFTDYSTSTDTEQTLPATSTDLAHTSPALAATTPETSHSPVASPSLQSSTAALTGGPTTGQTVARETEQTVVQLSPTSPEILVVQVTTEGAVTTEESPVDRDAATRLFPLTKESTTGPGPIEDNSLASPFLKTSPSPRTTPVSTAKVLTPPSTTSTVRSSTRSPTAPSSPAAVNSCTTHPCLHDGKCVVDLTTHPGYRCVCSPAWQGDNCSVDVNECLSNPCPPLATCNNTQGSFTCRCPVGYQLEKGICNLVRTFVTEFKLKKTFLNTTVEKHSDLREVENEITKMLNVCFSTLPGYTRSTAHVSRESSVVVMSLQATFSLASNVTLFDLADRMQKCVNSCWASAEVCQLLGSQRRIFRAGSLCKRKTPECDKETSICTDLDGVALCQCKSGYFQFNKMDHSCRACEDGYRLENETCMSCPFGLGGLNCGNPYQLITVVIAAAGGGLLLILGIALIVTCCRKNKNDISKLIFKSGDFQMSPYAEYPKNPRSQEWGREAIEMHENGSTKNLLQMTDVYYSPSSVRNPELERNGLYPAYTGLPGSRHSCIFPGQYNPSFISDESRRRDYF", "length": 1355, "header": "tr|A0A3Q1MIM0-1|A0ABI0NKD4_BOVIN Computationally mapped isoform of Heart development protein with EGF like domains 1 OS=Bos taurus OX=9913 GN=HEG1 PE=4 SV=1 CANONICAL=A0ABI0NKD4-1" }, "locus": { "chromosome": "1", "start_pos": 69501571, "end_pos": 69422857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068064.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068064.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069019.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069019.1" } ] } }, { "isoform_ac": "A0ABI0NKD4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4/entry#A0ABI0NKD4-1", "sequence": { "sequence": "MASPPLLLLLLPLLLLPPPAAPGTRGQPFSPAGAGPAWPTESSPGLKLPPSPTSPPERRGPASPGHRQTAPAPGAARRPGPSSRAPRSGSAAVVKNHWLESNTEPQIENITFDQNQVDFSTVVSKEGVMVQTPRKIHPSLDAPENITLQTETAAARGINDSSGRTEFTVPHYGPGRTTTLTSQSSTLALGKRHPPSSSSGSEARTAPLYMESGTSWGSPAGAQGLPEEVTVHTQMAATSVLSQSSLPAVEGGEETALPRQRSSSGPEPSWPPLSRTSAYSPPSDHPSSSGSTEDLNNSTAVHSSSVSGTESVHVATTFPNSVQRTPQSSATSLRPLNETEHFPEDSEIAITSSSVHSSPSEAELRRSSGVFGSPGNGAFTELSTEIAFGPTSSNISREFWQNDSPTSGGPQLASGSGAGNGSPVSQTETSSRSIPPVRGEESTALWFSTGSEPFAGAAGSSTSHPEVVNASVLTRFSASAPQSQGSDPALYEMSYSELATEALSSSSSESLGFSAPRGERSTTEDSPELGAGTKAEEGASWGVPGVRTHSPHTLATFAGVGERTLRSLTNRSTTSGDVERSMATTGEMESATQQGNMTVTGDARPVSGSLAATRTFGGHGVTGISYDGASSTDPDCRTSSEHTNYTCASSPFTKGERTLLSITDNSSSWDGRETSTSSVKISSSLSSDSSPSSQAQTERSNVSSHQGEHAQPSTGALVLSTASSPSHTPTLNTLTTLVPRDTDAKSVGGALSSSSSEPPLPLPSVSQSYQFSSTLPSAGASTHRLQSSPDAPTPLSSSPPPSSVSLTASAPASLSDSQTALPHAPFTPVLPRTRDAPVTSVRMSAVASSIPSSQTADPPKNQSSPYLKNTVTESKPPSLQTLPAEATKAVTVMSTLGIPSPRPFTDYSTSTDTEQTLPATSTDLAHTSPALAATTPETSHSPVASPSLQSSTAALTGGPTTGQTVARETEQTVVQLSPTSPEILVVQVTTEGAVTTEESPVDRDAATRLFPLTKESTTGPGPIEDNSLASPFLKTSPSPRTTPVSTAKVLTPPSTTSTVRSSTRSPTAPSSPAAVNSCTTHPCLHDGKCVVDLTTHPGYRCVCSPAWQGDNCSVDVNECLSNPCPPLATCNNTQGSFTCRCPVGYQLEKGICNLVRTFVTEFKLKKTFLNTTVEKHSDLREVENEITKMLNVCFSTLPGYTRSTAHVSRESSVVVMSLQATFSLASNVTLFDLADRMQKCVNSCWASAEVCQLLGSQRRIFRAGSLCKRKTPECDKETSICTDLDGVALCQCKSGYFQFNKMDHSCRACEDGYRLENETCMSCPFGLGGLNCGNPYQLITVVIAAAGGGLLLILGIALIVTCCRKNKNDISKLIFKSGDFQMSPYAEYPKNPRSQEWGREAIEMHENGSTKNLLQMTDVYYSPSSVRNPELERNGLYPAYTGLPGSRHSCIFPGQYNPSFISDESRRRDYF", "length": 1471, "header": "tr|A0ABI0NKD4-1|A0ABI0NKD4_BOVIN Isoform 1 of Heart development protein with EGF like domains 1 OS=Bos taurus OX=9913 GN=HEG1 PE=4 SV=1 CANONICAL=A0ABI0NKD4-1" }, "locus": { "chromosome": "1", "start_pos": 69501571, "end_pos": 69422857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146576.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146576.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105152.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105152.1" } ] } }, { "isoform_ac": "A0ABI0NZK9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4/entry#A0ABI0NZK9-1", "sequence": { "sequence": 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"length": 1383, "header": "tr|A0ABI0NZK9-1|A0ABI0NZK9_BOVIN Computationally mapped isoform of Heart development protein with EGF like domains 1 OS=Bos taurus OX=9913 GN=HEG1 PE=4 SV=1 CANONICAL=A0ABI0NKD4-1" }, "locus": { "chromosome": "1", "start_pos": 69491690, "end_pos": 69422857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149841.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149841.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107147.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107147.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 391, "start_aa": "Thr", "end_pos": 391, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr391", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 960, "start_aa": "Thr", "end_pos": 960, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr960", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:511689", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511689", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1111, "end_pos": 1113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1131, "end_pos": 1133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1170, "end_pos": 1172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1227, "end_pos": 1229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1317, "end_pos": 1319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1407, "end_pos": 1409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 701, "end_pos": 703, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NKD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKD4" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 1074, "end_pos": 1113, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 53, 391, 960 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 1111, "end_pos": 1113 }, { "start_pos": 1131, "end_pos": 1133 }, { "start_pos": 1170, "end_pos": 1172 }, { "start_pos": 1227, "end_pos": 1229 }, { "start_pos": 1317, "end_pos": 1319 }, { "start_pos": 1407, 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NLK2-1", "uniprot_ac": "A0ABI0NLK2", "uniprot_id": "A0ABI0NLK2_BOVIN", "mass": { "chemical_mass": 54255.0, "monoisotopic_mass": 54255.0 }, "refseq": { "ac": "XP_005209754", "name": "gamma-aminobutyric acid receptor subunit gamma-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209754" }, "gene_names": [ { "name": "GABRG2", "type": "recommended", "evidence": [ { "id": "A0ABI0NLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ] }, { "name": "GABRG2", "type": "synonym", "evidence": [ { "id": "XP_005209754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209754" } ] } ], "protein_names": [ { "name": "Gamma-aminobutyric acid receptor subunit gamma-2", "type": "recommended", "evidence": [ { "id": "A0ABI0NLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2/entry#names_and_taxonomy" } ] }, { "name": "GABA(A) receptor subunit gamma-2", "type": "synonym", "evidence": [ { "id": "A0ABI0NLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2/entry#names_and_taxonomy" } ] }, { "name": "gamma-aminobutyric acid receptor subunit gamma-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005209754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209754" } ] } ], "function": [ { "annotation": "Gamma subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain. GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interface(s). When activated by GABA, GABAARs selectively allow the flow of chloride across the cell membrane down their electrochemical gradient.", "evidence": [ { "database": "UniProtKB", "id": "G3MYR4", "url": "https://www.uniprot.org/uniprotkb/G3MYR4#function" }, { "database": "UniProtKB", "id": "ARBA00058949", "url": "https://www.uniprot.org/uniprotkb/ARBA00058949#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GABRG2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2", "locus": { "chromosome": "7", "start_pos": 73900293, "end_pos": 73708273, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010251", "url": "https://www.ensembl.org/id/ENSBTAG00000010251" } ] } } ], "crossref": [ { "id": "ENSBTAG00000010251", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010251", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19000", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19000", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "282240", "url": "https://www.ncbi.nlm.nih.gov/gene/282240", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AHYSLCF", "url": "https://omabrowser.org/oma/group/AHYSLCF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MIG7", "url": "https://www.orthodb.org/?gene=F1MIG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MYR4", "url": "https://www.orthodb.org/?gene=G3MYR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-977443", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-977443", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005209754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209754", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TBE3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBE3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGV6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRW3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRW3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYZ3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLK2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIG7", "url": "https://www.uniprot.org/uniprotkb/F1MIG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIG7-1", "url": "https://www.uniprot.org/uniprotkb/F1MIG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYR4", "url": "https://www.uniprot.org/uniprotkb/G3MYR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYR4-1", "url": "https://www.uniprot.org/uniprotkb/G3MYR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLTNIWSTGSSVYSTPVFSQKMTLWILLLLSLYPGLTRQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMTVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 467, "header": "tr|A0ABI0NLK2-1|A0ABI0NLK2_BOVIN Isoform 1 of Gamma-aminobutyric acid receptor subunit gamma-2 OS=Bos taurus OX=9913 GN=GABRG2 PE=3 SV=1 CANONICAL=A0ABI0NLK2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TBE3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2/entry#A0AAA9TBE3-1", "sequence": { "sequence": "MLILVPLKVKHKMTLWILLLLSLYPGLTRQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMTVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 457, "header": "tr|A0AAA9TBE3-1|A0ABI0NLK2_BOVIN Computationally mapped isoform of Gamma-aminobutyric acid receptor subunit gamma-2 OS=Bos taurus OX=9913 GN=GABRG2 PE=3 SV=1 CANONICAL=A0ABI0NLK2-1" }, "locus": { "chromosome": "7", "start_pos": 73899289, "end_pos": 73708288, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094470.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094470.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095307.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095307.1" } ] } }, { "isoform_ac": "A0AAA9TGV6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2/entry#A0AAA9TGV6-1", "sequence": { "sequence": "MTHAKSIHVAKMTLWILLLLSLYPGLTRQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMTVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 456, "header": "tr|A0AAA9TGV6-1|A0ABI0NLK2_BOVIN Computationally mapped isoform of Gamma-aminobutyric acid receptor subunit gamma-2 OS=Bos taurus OX=9913 GN=GABRG2 PE=3 SV=1 CANONICAL=A0ABI0NLK2-1" }, "locus": { "chromosome": "7", "start_pos": 73899289, "end_pos": 73752444, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112080.2", "url": "https://www.ensembl.org/id/ENSBTAT00000112080.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095450.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095450.1" } ] } }, { "isoform_ac": "A0AAA9TRW3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2/entry#A0AAA9TRW3-1", "sequence": { "sequence": "MDLGEYVLTRQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMTVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 446, "header": "tr|A0AAA9TRW3-1|A0ABI0NLK2_BOVIN Computationally mapped isoform of Gamma-aminobutyric acid receptor subunit gamma-2 OS=Bos taurus OX=9913 GN=GABRG2 PE=3 SV=2 CANONICAL=A0ABI0NLK2-1" }, "locus": { "chromosome": "7", "start_pos": 73899289, "end_pos": 73772069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104869.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104869.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099775.2", "url": "https://www.ensembl.org/id/ENSBTAP00000099775.2" } ] } }, { "isoform_ac": "A0AAA9TYZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2/entry#A0AAA9TYZ3-1", "sequence": { "sequence": "MTLWILLLLSLYPGYQGNIPSQIVHHLSTHKNNPPDSTHTIRISSQSQSLTRQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMTVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 480, "header": "tr|A0AAA9TYZ3-1|A0ABI0NLK2_BOVIN Computationally mapped isoform of Gamma-aminobutyric acid receptor subunit gamma-2 OS=Bos taurus OX=9913 GN=GABRG2 PE=3 SV=2 CANONICAL=A0ABI0NLK2-1" }, "locus": { "chromosome": "7", "start_pos": 73899289, "end_pos": 73772519, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110086.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110086.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101931.2", "url": "https://www.ensembl.org/id/ENSBTAP00000101931.2" } ] } }, { "isoform_ac": "A0ABI0NLK2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2/entry#A0ABI0NLK2-1", "sequence": { "sequence": "MSLTNIWSTGSSVYSTPVFSQKMTLWILLLLSLYPGLTRQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMTVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 467, "header": "tr|A0ABI0NLK2-1|A0ABI0NLK2_BOVIN Isoform 1 of Gamma-aminobutyric acid receptor subunit gamma-2 OS=Bos taurus OX=9913 GN=GABRG2 PE=3 SV=1 CANONICAL=A0ABI0NLK2-1" }, "locus": { "chromosome": "7", "start_pos": 73899289, "end_pos": 73772453, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139539.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139539.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105669.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105669.1" } ] } }, { "isoform_ac": "F1MIG7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2/entry#F1MIG7-1", "sequence": { "sequence": "MSLTNIWSTGSSVYSTPVFSQKMTLWILLLLSLYPGLTRQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMTVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 475, "header": "tr|F1MIG7-1|A0ABI0NLK2_BOVIN Computationally mapped isoform of Gamma-aminobutyric acid receptor subunit gamma-2 OS=Bos taurus OX=9913 GN=GABRG2 PE=3 SV=1 CANONICAL=A0ABI0NLK2-1" }, "locus": { "chromosome": "7", "start_pos": 73899289, "end_pos": 73772453, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013543.5", "url": "https://www.ensembl.org/id/ENSBTAT00000013543.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013543.3", "url": "https://www.ensembl.org/id/ENSBTAP00000013543.3" } ] } }, { "isoform_ac": "G3MYR4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2/entry#G3MYR4-1", "sequence": { "sequence": "MSLTNIWSTGSSVYSTPVFSQKMTLWILLLLSLYPGLTRQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMTVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPIHHSHTGDIVETWSGIYQVKLTYPAPSLLSQAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 498, "header": "tr|G3MYR4-1|A0ABI0NLK2_BOVIN Computationally mapped isoform of Gamma-aminobutyric acid receptor subunit gamma-2 OS=Bos taurus OX=9913 GN=GABRG2 PE=3 SV=2 CANONICAL=A0ABI0NLK2-1" }, "locus": { "chromosome": "7", "start_pos": 73899289, "end_pos": 73772453, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066231.4", "url": "https://www.ensembl.org/id/ENSBTAT00000066231.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054701.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054701.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-977443", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-977443", "resource": "Reactome", "description": "GABA receptor activation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RR72-1", "protein_name": "Gamma-aminobutyric acid receptor subunit gamma-2", "gene_name": "GABRG2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTNIWSTGSSVYSTPVFSQKMTVWILLLLSFYPGLTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMTVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 475 }, "evidence": [ { "id": "A0ABI0NLK2", "url": "https://omabrowser.org/oma/group/A0ABI0NLK2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P18507-2", "protein_name": "Gamma-aminobutyric acid receptor subunit gamma-2", "gene_name": "GABRG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 475 }, "evidence": [ { "id": "A0ABI0NLK2", "url": "https://omabrowser.org/oma/group/A0ABI0NLK2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P18508-1", "protein_name": "Gamma-aminobutyric acid receptor subunit gamma-2", "gene_name": "Gabrg2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSPNTWSTGSTVYSPVFSQKMTLWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 466 }, "evidence": [ { "id": "A0ABI0NLK2", "url": "https://omabrowser.org/oma/group/A0ABI0NLK2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21548-1", "protein_name": "Gamma-aminobutyric acid receptor subunit gamma-2", "gene_name": "GABRG2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTPSNPTRLGSTALLNPAFSLKMMVWALVFLSLIQCSTQKGDDDYEDYTSNKTWVLTPKVHESDVTLILNGLLEGYDNKLRPDIGVKPTVIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDAHSCPLEFSSYGYPREEIIYQWKRSSVEVGDTRSWRLYQFSFTGLRNTTEVVKTTSGDYVVMSVYFNLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL", "length": 474 }, "evidence": [ { "id": "A0ABI0NLK2", "url": "https://omabrowser.org/oma/group/A0ABI0NLK2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P22723-1", "protein_name": "Gamma-aminobutyric acid receptor subunit gamma-2", "gene_name": "Gabrg2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "gamma-aminobutyric acid signaling pathway", "id": "GO:0007214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007214", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "pmid": "" }, { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "pmid": "" }, { "name": "synaptic transmission, GABAergic", "id": "GO:0051932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051932", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "pmid": "" }, { "name": "inhibitory synapse assembly", "id": "GO:1904862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904862", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "pmid": "" }, { "name": "cellular response to histamine", "id": "GO:0071420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071420", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GABA-A receptor activity", "id": "GO:0004890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004890", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "pmid": "" }, { "name": "GABA-gated chloride ion channel activity", "id": "GO:0022851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022851", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "pmid": "" }, { "name": "extracellular ligand-gated monoatomic ion channel activity", "id": "GO:0005230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005230", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLK2" } ], "pmid": "" }, { "name": 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"https://www.uniprot.org/uniprotkb/A0A3Q1MY15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MY15-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MY15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMA6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGADYEVLSVREQLFHERVRECIISTLLFATLYIFCHIALTHFKKPAEFTTVDEEDATVNKIALELCTFTLAVALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLIFLMPFAYFFTESEGFAGSRKGVLARVYETVVMLMLLTLLVLGMVWVASAIVDNNKASRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLHCSAFEEAALTRRICNPTSCWLPLDMELLHRQVLALQTQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAIHILELLIDEAAMPRGMQGASLGQVSFSKLGSFGAVIQVVLIFYLMVSSVVGFYSSPLFRGLRPRWHDTAMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSGFPRVSKKTQHQ", "length": 489, "header": "tr|E1BMA6-1|E1BMA6_BOVIN Isoform 1 of Limb development membrane protein 1 like OS=Bos taurus OX=9913 GN=LMBR1L PE=3 SV=1 CANONICAL=E1BMA6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MY15-1", "url": "https://www.uniprot.org/uniprotkb/E1BMA6/entry#A0A3Q1MY15-1", "sequence": { "sequence": "MEGADYEVLSVREQLFHERVRECIISTLLFATLYIFCHIALTHFKKPAEFTTVDEEDATVNKIALELCTFTLAVALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLIFLMPFAYFFTESEGFAGSRKGVLARVYETVVMLMLLTLLVLGMVWVASAIVDNNKASRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLHCSAFEEAALTRRICNPTSCWLPLDMELLHRQVLALQTQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAIHILELLIDEAAMPRGMQGASLGQVSFSKLGSFGAVIQVVLIFYLMVSSVVGFYSSPLFRGLRPRWHDTAMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGERVSGRGWWGGCKMELSGTVVIPSRGDGIFTTHSVASED", "length": 507, "header": "tr|A0A3Q1MY15-1|E1BMA6_BOVIN Computationally mapped isoform of Limb development membrane protein 1 like OS=Bos taurus OX=9913 GN=LMBR1L PE=3 SV=2 CANONICAL=E1BMA6-1" }, "locus": { "chromosome": "5", "start_pos": 30725680, "end_pos": 30714092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069186.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069186.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060809.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060809.2" } ] } }, { "isoform_ac": "E1BMA6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMA6/entry#E1BMA6-1", "sequence": { "sequence": "MEGADYEVLSVREQLFHERVRECIISTLLFATLYIFCHIALTHFKKPAEFTTVDEEDATVNKIALELCTFTLAVALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLIFLMPFAYFFTESEGFAGSRKGVLARVYETVVMLMLLTLLVLGMVWVASAIVDNNKASRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLHCSAFEEAALTRRICNPTSCWLPLDMELLHRQVLALQTQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAIHILELLIDEAAMPRGMQGASLGQVSFSKLGSFGAVIQVVLIFYLMVSSVVGFYSSPLFRGLRPRWHDTAMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSGFPRVSKKTQHQ", "length": 489, "header": "tr|E1BMA6-1|E1BMA6_BOVIN Isoform 1 of Limb development membrane protein 1 like OS=Bos taurus OX=9913 GN=LMBR1L PE=3 SV=1 CANONICAL=E1BMA6-1" }, "locus": { "chromosome": "5", "start_pos": 30725788, "end_pos": 30714092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061378.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061378.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053276.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053276.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539015", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539015", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JVJ7-1", "protein_name": "Limb development membrane protein 1-like", "gene_name": "Lmbr1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAADYEVLSVREQLFHDRVRECIISILLFATLYILCHIFLTRFKKPAEFTTVDDEDATVNKIALELCTFTLAVALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLVFLMPFAYFFTESEGFAGSRKGVLGRVYETVVMLILLTLLVLGMVWVASAIVDNDKASRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLNCSAFEEAALTRRICNPTSCWLPLDMELLHRQVLALQAQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAVHILELLIDEAAMPRGMQDAALGQVSFSKLGSFGAIIQVVLIFYLMVSSVVGFYSSPLFGSLRPRWHDTSMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSGFPRGSRKKQHQ", "length": 489 }, "evidence": [ { "id": "E1BMA6", "url": "https://omabrowser.org/oma/group/E1BMA6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A1D5PDR6-1", "protein_name": "Limb development membrane protein 1 like", "gene_name": "LMBR1L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPVELDALAVREQLFHERVRECLICALLFASLYILCHFVIRHFKKQTDFAAVHDDEDAAVNRIALGLCTFTLAVALGAVLLLPFSIISNEVLLSFPHNYYIQWLNGSLIHGLWNLVFLFSNLSLVFLMPFAYFFTESEGFAGSKKGIMARVYETSVVLLLLTLLVLGMVWVASAITGNDAVSRQSLYDLWECYLPYLYSCISLFGVLLLLLCTPFGLSTMFTVTGKLLVKPRLLEDLDEQLSCTRFEEAAVSRRITSGKASCWLNLNTALLREQLLSIRSKRKKLELRHRASPWQRNVGYPLAMLGLLALTGISVLIVCFHVLELLLDDAAMPRGMQDTALGQVSFSILGSFGAALQVVLIFYLMLSSVVGFYSSPLFTRLLPERQDTPLTKIIGNCVSLLVLSSALPVFSRTLGITRFDLLGDFGRFNWLGNFYIVFIYNMGFAALTTLCLVKRVTWAVQEELIRAFGLHKLPLPVPRSRPQGGRC", "length": 488 }, "evidence": [ { "id": "E1BMA6", "url": "https://omabrowser.org/oma/group/E1BMA6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6UX01-1", "protein_name": "Protein LMBR1L", "gene_name": "LMBR1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAPDYEVLSVREQLFHERIRECIISTLLFATLYILCHIFLTRFKKPAEFTTVDDEDATVNKIALELCTFTLAIALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLIFLMPFAYFFTESEGFAGSRKGVLGRVYETVVMLMLLTLLVLGMVWVASAIVDKNKANRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLYCSAFEEAALTRRICNPTSCWLPLDMELLHRQVLALQTQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAIHILELLIDEAAMPRGMQGTSLGQVSFSKLGSFGAVIQVVLIFYLMVSSVVGFYSSPLFRSLRPRWHDTAMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSGFPQASRKTQHQ", "length": 489 }, "evidence": [ { "id": "E1BMA6", "url": "https://omabrowser.org/oma/group/E1BMA6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D1E5-1", "protein_name": "Protein LMBR1L", "gene_name": "Lmbr1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAADYEVLSVREQLFHDRVRECIISILLFATLYILCHIFLTRFKKPAEFTTVDDEDATVNKIALELCTFTLAVALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLVFLMPFAYFFTESEGFAGSRKGVLGRVYETVVMLILLTLLVLGMVWVASAIVDNDKASRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLNCSAFEEAALTRRICNPTSCWLPLDMELLHRQVLALQAQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAVHILELLIDEAAMPRGMQDAALGQASFSKLGSFGAIIQVVLIFYLMVSSVVGFYSSPLFGSLRPRWHDTSMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSGFPRASRKKQHQ", "length": 489 }, "evidence": [ { "id": "E1BMA6", "url": "https://omabrowser.org/oma/group/E1BMA6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VC35-1", "protein_name": "Protein Lilipod", "gene_name": "lili", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDEEEEEEVTDLKLQLFHNTVREHIIFLLLIILLYSSSYVVVSRFRRRDRDDLYSNDEDEVLVYRISFWLCTFTLAVAEGAAMLLPVSIASNEVLLLYPNSYYVKWLNSSLIQGLWNHVFLFSNLSLFIFLPFVYLFSESTGFVGNKKGILPRVYETFTVFMLMAIIVLVLTAVLSAVFGIEKLQFFWFLNLGSVHLPFLYSCVSFLGVMLMLICTPYGFVRLFGVVNQVLVRPMLLRDVNEEFSAFYMEEASVKRKLAHIELHNVSIADAANGGRLGNRIGLGRGRTFYPQPLLQHSQAHLYQRKAMASDVDELNDRLRELDSERKELDKLRTSSTFQRTFVYPLAMLLLLFCTAVTILLVVQNTLELLIGIKALPLSTRQFALGISSLSKLGPFGAGLEVCLIFYLGATSVVGFYSMPFMRKVCPKRRQTSLPQLMLNCGFMLVLSSALPLLSRIIGITNFDLLGDFGAIEWLGNFQIVLLYNLVFGTTTALCLANKFTATVRRELRARLVENYVLFTNYISFIN", "length": 527 }, "evidence": [ { "id": "E1BMA6", "url": "https://omabrowser.org/oma/group/E1BMA6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6" } ], "pmid": "" }, { "name": "hematopoietic stem cell differentiation", "id": "GO:0060218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060218", "evidence": [ { "database": "UniProtKB", "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6" } ], "pmid": "" }, { "name": "T cell apoptotic process", "id": "GO:0070231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070231", "evidence": [ { "database": "UniProtKB", "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6" } ], "pmid": "" }, { "name": "T cell proliferation", "id": "GO:0042098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042098", "evidence": [ { "database": "UniProtKB", "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BMA6", "url": "https://www.uniprot.org/uniprotkb/E1BMA6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMA6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 489, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMA6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMA6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 121, "end_pos": 123 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNC6-1", "uniprot_ac": "E1BNC6", "uniprot_id": "E1BNC6_BOVIN", "mass": { "chemical_mass": 60522.0, "monoisotopic_mass": 60522.0 }, "refseq": { "ac": "NP_001178960", "name": "man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178960" }, "gene_names": [ { "name": "RFT1", "type": "recommended", "evidence": [ { "id": "E1BNC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNC6" } ] }, { "name": "RFT1", "type": "synonym", "evidence": [ { "id": "NP_001178960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178960" } ] } ], "protein_names": [ { "name": "Protein RFT1 homolog", "type": "recommended", "evidence": [ { "id": "E1BNC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNC6/entry#names_and_taxonomy" } ] }, { "name": "RFT1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001178960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178960" } ] }, { "name": "man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "type": "synonym", "evidence": [ { "id": "NP_001178960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178960" } ] } ], "function": [ { "annotation": "Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1N312", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N312#function" }, { "database": "UniProtKB", "id": "RU365067", "url": "https://www.uniprot.org/uniprotkb/RU365067#function" }, { "database": "UniProtKB", "id": "ARBA00045912", "url": "https://www.uniprot.org/uniprotkb/ARBA00045912#function" }, { "database": "UniProtKB", "id": "E1BNC6", "url": "https://www.uniprot.org/uniprotkb/E1BNC6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNC6", "url": "https://www.uniprot.org/uniprotkb/E1BNC6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RFT1", "url": "https://www.uniprot.org/uniprotkb/E1BNC6", "locus": { "chromosome": "22", "start_pos": 47852306, "end_pos": 47812898, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020973", "url": "https://www.ensembl.org/id/ENSBTAG00000020973" } ] } } ], "crossref": [ { "id": "E1BNC6", "url": "https://alphafold.ebi.ac.uk/entry/E1BNC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020973", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020973", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "504597", "url": "https://www.ncbi.nlm.nih.gov/gene/504597", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504597", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504597", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WPGKLFG", "url": "https://omabrowser.org/oma/group/WPGKLFG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N312", "url": "https://www.orthodb.org/?gene=A0A3Q1N312", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BNC6", "url": "https://www.orthodb.org/?gene=E1BNC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13117:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13117:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04506", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04506", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178960", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178960", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N312", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N312", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N312-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N312-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNC6", "url": "https://www.uniprot.org/uniprotkb/E1BNC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNC6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSREVLGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRLTLLYSTTIFLAREAFRRACLSGAAQRDWSQTLNLLWLTVPLGVFWSLFLGWVWLQLLEVPDPHVVPHYGTGVVVFGFSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTALLVLWLPHWGLYIFSLAQLFYTTLLVLCYVIYFAKVLGSPESAKQQALPVSRMTDLLPSMTRSRAFVNWEEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLLFQPIEESFYIFFAKVLEREKDATLQKQEDVAVAAVVLESLLKLALLTGLTITVFGFAYSQLVLDIYGGAMLSSGSGPVLLRAYCLYVLLLAINGVTECFTFAAMSKAEVDRYNFTMLALSSSFLMLSYVLTRWCGSVGFILANCFNMGIRIMQSLYFIYRYYRKSPHRPLDGLFLSPVLLGTFALSGGITAVSEVFLCCERGWLARLAHIAVGALCLGVTLGTAFLTETKLIHFLRTQLGVPRLADKMT", "length": 541, "header": "tr|E1BNC6-1|E1BNC6_BOVIN Isoform 1 of Protein RFT1 homolog OS=Bos taurus OX=9913 GN=RFT1 PE=3 SV=1 CANONICAL=E1BNC6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N312-1", "url": "https://www.uniprot.org/uniprotkb/E1BNC6/entry#A0A3Q1N312-1", "sequence": { "sequence": "MGSREVLGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRVPLGVFWSLFLGWVWLQLLEVPDPHVVPHYGTGVVVFGFSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTALLVLWLPHWGLYIFSLAQLFYTTLLVLCYVIYFAKVLGSPESAKQQALPVSRMTDLLPSMTRSRAFVNWEEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLLFQPIEESFYIFFAKVLEREKDATLQKQEDVAVAAVVLESLLKLALLTGLTITVFGFAYSQLVLDIYGGAMLSSGSGPVLLRAYCLYVLLLAINGVTECFTFAAMSKAEVDRYNFTMLALSSSFLMLSYVLTRWCGSVGFILANCFNMGIRIMQSLYFIYRYYRKSPHRPLDGLFLSPVLLGTFALSGGITAVSEVFLCCERGWLARLAHIAVGALCLGVTLGTAFLTETKLIHFLRTQLGVPRLADKMT", "length": 502, "header": "tr|A0A3Q1N312-1|E1BNC6_BOVIN Computationally mapped isoform of Protein RFT1 homolog OS=Bos taurus OX=9913 GN=RFT1 PE=3 SV=1 CANONICAL=E1BNC6-1" }, "locus": { "chromosome": "22", "start_pos": 47851448, "end_pos": 47812899, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080417.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080417.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063729.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063729.1" } ] } }, { "isoform_ac": "E1BNC6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNC6/entry#E1BNC6-1", "sequence": { "sequence": "MGSREVLGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRLTLLYSTTIFLAREAFRRACLSGAAQRDWSQTLNLLWLTVPLGVFWSLFLGWVWLQLLEVPDPHVVPHYGTGVVVFGFSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTALLVLWLPHWGLYIFSLAQLFYTTLLVLCYVIYFAKVLGSPESAKQQALPVSRMTDLLPSMTRSRAFVNWEEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLLFQPIEESFYIFFAKVLEREKDATLQKQEDVAVAAVVLESLLKLALLTGLTITVFGFAYSQLVLDIYGGAMLSSGSGPVLLRAYCLYVLLLAINGVTECFTFAAMSKAEVDRYNFTMLALSSSFLMLSYVLTRWCGSVGFILANCFNMGIRIMQSLYFIYRYYRKSPHRPLDGLFLSPVLLGTFALSGGITAVSEVFLCCERGWLARLAHIAVGALCLGVTLGTAFLTETKLIHFLRTQLGVPRLADKMT", "length": 541, "header": "tr|E1BNC6-1|E1BNC6_BOVIN Isoform 1 of Protein RFT1 homolog OS=Bos taurus OX=9913 GN=RFT1 PE=3 SV=1 CANONICAL=E1BNC6-1" }, "locus": { "chromosome": "22", "start_pos": 47851448, "end_pos": 47812899, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061626.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061626.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053575.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053575.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:504597", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504597", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AQX7-1", "protein_name": "Protein RFT1 homolog", "gene_name": "RFT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSREVLGQAARLASSGLLLQVLFRVITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTIFLAREAFRRACLSGGTQRHWSQTLNLLWLTVPLGVFWSLFLGWVWLQLLEVPDPNVVPHYGTGVAAFGLSAVVELLGEPLWVLAQAHMFVRLKVIAESLSVILKSILTALLVLWLPHWGLYIFSLAQLFFTAVLVLCYVIYFTKLLGSPESSKGQVLPVSRMTDLLPSITRSRAFVNWEEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLEREKDATLQKQEDVAVAAAVLESLLKLALLTGLTITVFGFAYSQLALDIYGGAMLSSGSGPVLLRAYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFTMLALSSSFLGLSYLLTHWCGSVGFILANCFNMGIRITQSLRFIHRYYQKSPHRPLASLYLSPVLLGAFALSGGITAVSEVFLCCERGWPARLAHITVGALCLGATLRTVFLTETKLIHFLRTQLAVSRLADKTT", "length": 541 }, "evidence": [ { "id": "E1BNC6", "url": "https://omabrowser.org/oma/group/E1BNC6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2QDF7-1", "protein_name": "Protein RFT1 homolog", "gene_name": "Rft1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSQEALGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRLTLLYSTTIFLAREAFRKACLSGGAQRDWSQTLNLLWLTVPLGVFWSLLLGWVWLQLLEVPDPDVVPYYGAGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVLAESVSVILRSILTAFLVLWLPHWGLYIFSLAQLFYTTVLVLCYVIYLIKLLRSPESAKQLTLPVSRITQLLPSITRSRAFVNWKEAKLTWSFFKQSFLKQILTEGERYVMTFFNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLEREKDATHQKQEDIAVAAAVLESLLKLALLTGLTITVFGFAYSQLALDIYGGAMLSSGSGPVLMCSYCFYVLLLAINGVTECFTFAAMSKEEVDRYNFTMLALSSSFLVLSYLLTSWCGSVGFILANCFNMCIRITQSLSFIHHYFQRSPHKPLAGLNLSPFLLGVFALSGGITSVSETLLCCEQGWPARLAHIAVGTICLGVTLGTAFFTETKLINFLRTQLGRSRLSDKMT", "length": 541 }, "evidence": [ { "id": "E1BNC6", "url": "https://omabrowser.org/oma/group/E1BNC6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V1AJA2-1", "protein_name": "Protein RFT1 homolog", "gene_name": "RFT1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAARAALRQTARLASSSALLQVLFRAVTFGLNALTLRYLSRELLGVVSVRLTLLYSTAVFLAREAFRRACLSGGAERSWAATINLLWLTVPLGVFWSAFLGFVWLHLLEVPDPSVVPHYRAGVVAFGLSAVVELLGEPCWVLAQAHLFVRLKVIAESLSIVSKCILTVVLVVLYPQWGLYIFSLAQLFYTSVLVTCYVVYFAKFLGSPEATKKSFPITRMKALLPNLMADKTFLNWKEARLTWSFFKQSFLKQILTEGERYVMTFLNVINFGDQGVYDAVNNLGSLVARFIFLPIEESFYVFFAQVLERGKNVKDQKQDDVAMAANVLELLLKLVLLIGLTIAVFGYAFSQLALDIYGGSMLSSGTGPDLLRCYSLYVLFLAVNGVTECFTFASMCKEEVDRYNFVMLALSFTFLCISYFLTRWHGSVGFILANCFNMGIRIAHSIHYIYGYFKESSYRPLTGLLPSPFLVLAYIISGGITVYSEAFFCCDKGWTARLIHISIGALCFAATTVTMLCTETKLVRFVRSQFLSQYMKKGT", "length": 539 }, "evidence": [ { "id": "E1BNC6", "url": "https://omabrowser.org/oma/group/E1BNC6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A6W4-1", "protein_name": "Protein RFT1 homolog", "gene_name": "Rft1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSQEVLGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTIFLAREAFRRACLSGGTQRDWTQTLNLLWLTVPLGIFWSLCLGWVWLQLLEVPDPNVVPYYGTGVLLFGLSAVVELLGEPFWVLAQAHMFVKLKVLAESMSVILRSVLTALLVLWLPHWGLYIFSLAQLLYTAVLVLCYMLYLIKLLRSPESSKQLTLPISKVTQLLPSISRRKAFVNWNEARLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGIYDIVNNLGSLVARLIFQPVEESFYIFFAKVLEREKDASLQKQDDVAVAAAVLESLLKLALLTGLTVTVFGFAYSQLALDIYGGAMLSSGSGPVLMRCYCLYVLLLAVNGVTECFTFAAMSKEDVDRYNFTMLALSSSFLVLSYLLTSWCGSVGFIMANCFNMGIRITQSLSFIHHYFQESPHRPLAGLLLSPVLLGVFVLSAGITSVSEAFLCCERGWPARLAHIAVGTICLGVTLGTAFLTETKLIHFLRTQLGRSRLGDKMT", "length": 541 }, "evidence": [ { "id": "E1BNC6", "url": "https://omabrowser.org/oma/group/E1BNC6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7EXE6-1", "protein_name": "Protein RFT1 homolog", "gene_name": "rft1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSEDVLKSASTLASYNVLLQVMFRVLTFLLNAFTLRFVSKELIGVVNVRLMLLYSTLVFLSREAFRRACLSGEGAGRNWRQVINLLWLTFPLGCVWGVLLVCVWWWVLQAPDPDSIPHYVPAVGLFCVAALTELLAEPLWVLAHAHMFVRLKVIAESLAMIAKCLVTVVLVVSAPQWGLFIFSAAQCVYTGFLLTCYVVYFIHFLGSEEAEKKSFPVYRMTDLLPSKVDHEPLLNWKLTTLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIINNLGSMVARFLFLPIEESFYVFFAKVLERGRDVQHQKQEEVSMAAEVLECLLKLVLLIGLIITVFGYAYSHLALDIYGGELLSNGAGPALLRCYSCYVLLLAINGVTECFVFAAMSKEEVDRYNLVMLGLSASFLLLSYWLTWMFGGVGFILANCCNMALRITHSIVYIRQYFLQSEHRPLWGLRPHSAVLVALGVSAVITAFSESVFCCDGGWLLRLFHVAVGAVCLLTVVITVFLTETRLVQFVKTQLLPKYNKKLT", "length": 540 }, "evidence": [ { "id": "E1BNC6", "url": "https://omabrowser.org/oma/group/E1BNC6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P38206-1", "protein_name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "gene_name": "RFT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAKKNSQLPSTSEQILERSTTGATFLMMGQLFTKLVTFILNNLLIRFLSPRIFGITAFLEFIQGTVLFFSRDAIRLSTLRISDSGNGIIDDDDEEEYQETHYKSKVLQTAVNFAYIPFWIGFPLSIGLIAWQYRNINAYFITLPFFRWSIFLIWLSIIVELLSEPFFIVNQFMLNYAARSRFESIAVTTGCIVNFIVVYAVQQSRYPMGVVTSDIDKEGIAILAFALGKLAHSITLLACYYWDYLKNFKPKKLFSTRLTKIKTRENNELKKGYPKSTSYFFQNDILQHFKKVYFQLCFKHLLTEGDKLIINSLCTVEEQGIYALLSNYGSLLTRLLFAPIEESLRLFLARLLSSHNPKNLKLSIEVLVNLTRFYIYLSLMIIVFGPANSSFLLQFLIGSKWSTTSVLDTIRVYCFYIPFLSLNGIFEAFFQSVATGDQILKHSYFMMAFSGIFLLNSWLLIEKLKLSIEGLILSNIINMVLRILYCGVFLNKFHRELFTDSSFFFNFKDFKTVIIAGSTICLLDWWFIGYVKNLQQFVVNVLFAMGLLALILVKERQTIQSFINKRAVSNSKDV", "length": 574 }, "evidence": [ { "id": "E1BNC6", "url": "https://omabrowser.org/oma/group/E1BNC6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54IV7-1", "protein_name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "gene_name": "rft1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQPQTESNVLKNGLVGAFYLIGLQIISRLFTFIINTLVIVGVDDSIFGVSAIQYQLLSSIILFLSREAIRRACTRVNITDKLNNDNNLKSVINLSWLVLPIGIGLSIIFENFFLYTSTKETLEILNYHYGLRLFTISSILELLSEPMYILAQNLLLFKIRTTVEGFALFFKTFSTYYFIVILNMGLIGFGYAQILYSLTLVIGYFGYFLINIINNNKNKDNKEFSNCFKSIDQLFPKFSTRIDRNLIKLSLLYTWQSIYKLLLQEGEKFVLFFSETNQGQAIFAIVSNLGSLIVRFLFLPIEETCFLMFPKLFPTINNNNNNNNNNNNNNNNNNKNQENNNNNDDFKNGANVLIVIMKFLILVSLVFTCFGPGFSHLLLNLLYNNKFRDTNAGVLLGFYCIYVGFLAINGVSESFVHSVAKEDQLKTVNWVLIIIGFIYLLFTLIFCKLFQNIGIILANCLNIKLSNMIPNKMVLLSFIISFIITNLSNKYIYNAVSFKSTCIHLLIGIICFIQTCTFIYLKEWVSIKEFKKILSNKNK", "length": 540 }, "evidence": [ { "id": "E1BNC6", "url": "https://omabrowser.org/oma/group/E1BNC6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8C3B8-1", "protein_name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "gene_name": "Rft1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQEVLGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRLTLLYSTTTFLAREAFRRACLSGGAQRDWSQTLNLLWLTVPLGIFWSSCLGWVWLQLLEVPDPDVVPYYGTGVLFFGLSAVVELLGEPFWVLAQAHMFVKLKVLAESMSVILRSVLTALLVLWLPHWGLYIFSLAQLLYTTVLVLCYAIYLIQLLRSPESAKQLTLPVSRVTQLLPSISRSRAFVNWKEAGLAWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPVEESFYLFFAKVLEREKDASLQKQDDVAVAAAVLESLLKLALLTGLTMTVFGFAYSQLALDIYGGAMLSSGSGPVLMRCYCLYVLLLAINGVTECFMFAAMSKEEVDRYNFTMLALSSSFLVLSYLLTSWCGSVGFIMANCFNMGIRITQSLSFIHHYFRESPHRPLAGLRLSPVLLGVFILSAGITSVSEAFLCCERGWPARLAHIAVGTICLGVTLGTAFLTETKLIHFLRTQLGRSRLSDKMT", "length": 541 }, "evidence": [ { "id": "E1BNC6", "url": "https://omabrowser.org/oma/group/E1BNC6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AA3-1", "protein_name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "gene_name": "RFT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSQEVLGHAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTLFLAREAFRRACLSGGTQRDWSQTLNLLWLTVPLGVFWSLFLGWIWLQLLEVPDPNVVPHYATGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTAFLVLWLPHWGLYIFSLAQLFYTTVLVLCYVIYFTKLLGSPESTKLQTLPVSRITDLLPNITRNGAFINWKEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLERGKDATLQKQEDVAVAAAVLESLLKLALLAGLTITVFGFAYSQLALDIYGGTMLSSGSGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSSSFLVLSYLLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGGVTAVSEVFLCCEQGWPARLAHIAVGAFCLGATLGTAFLTETKLIHFLRTQLGVPRRTDKMT", "length": 541 }, "evidence": [ { "id": "E1BNC6", "url": "https://omabrowser.org/oma/group/E1BNC6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Y123-1", "protein_name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARNVLESSLLGAGFSIIFQILCRILTFGINAYIVRHVGREVLGIMNVRLLLLESTLLFLSREAINRAALSANAQQGDRCSWAQLINQMWLTVPICAVLCAPCLYIWLNWLSAVDAIYASQYEFACYAVAFSCVLELMAESAVFVAQVFCFVKLKILLNTLHILVRSAIFLWIVTGDRSAAINAFAIAQLSSAVTIVLGQYGFFYFYLKGFKDFVTQQAKKKPVAPKAWQVSLYEHMDDFPFKQLSDFLPGVMFNPNGKHFNRELQTLTLSFVKQGVLKQILTEGEKYVMSVSPVLSFGEQATYDVVNNLGSMAARFIFRPIEDSSYFYFTQTLSRDIKLAKQPQERVRQASSVLNNLLLGVSSIGLIAFTFGQSYSYPVLLLYGGPDFVAGGLPQSLLQWHCLAIYLLAVNGISEGYMFATNTSRDIDKYNYLMAIFSVSFLVLSYILTGIFGPVGFIFANCINMLSRILYSTYYIRHQYRPLSLDPLLGLWPGKLFGCTLFLAGIVCYWYQSSDLATHLGVGVLAGLACLLSWALAHRDLVRLAWRYGRRIKIE", "length": 556 }, "evidence": [ { "id": "E1BNC6", "url": "https://omabrowser.org/oma/group/E1BNC6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BNC6", "url": "https://www.uniprot.org/uniprotkb/E1BNC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "E1BNC6", "url": "https://www.uniprot.org/uniprotkb/E1BNC6" } ], "pmid": "" }, { "name": "glycolipid translocation", "id": "GO:0034203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034203", "evidence": [ { "database": "UniProtKB", "id": "E1BNC6", "url": "https://www.uniprot.org/uniprotkb/E1BNC6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glycolipid floppase activity", "id": "GO:0034202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034202", "evidence": [ { "database": "UniProtKB", "id": "E1BNC6", "url": "https://www.uniprot.org/uniprotkb/E1BNC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNC6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 541, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNC6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNC6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 405, "end_pos": 407 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNN7-1", "uniprot_ac": "E1BNN7", "uniprot_id": "E1BNN7_BOVIN", "mass": { "chemical_mass": 77930.0, "monoisotopic_mass": 77930.0 }, "refseq": { "ac": "NP_001136439", "name": "ubiquitin-like modifier-activating enzyme ATG7 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001136439" }, "gene_names": [ { "name": "ATG7", "type": "recommended", "evidence": [ { "id": "E1BNN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ] }, { "name": "ATG7", "type": "synonym", "evidence": [ { "id": "NP_001136439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001136439" } ] } ], "protein_names": [ { "name": "Ubiquitin-like modifier-activating enzyme ATG7", "type": "recommended", "evidence": [ { "id": "E1BNN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNN7/entry#names_and_taxonomy" } ] }, { "name": "ATG7 autophagy related 7 homolog", "type": "synonym", "evidence": [ { "id": "NP_001136439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001136439" } ] }, { "name": "Autophagy-related protein 7", "type": "synonym", "evidence": [ { "id": "E1BNN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNN7/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-like modifier-activating enzyme ATG7 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001136439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001136439" } ] } ], "function": [ { "annotation": "E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1N3C3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3C3#function" }, { "database": "UniProtKB", "id": "RU366022", "url": "https://www.uniprot.org/uniprotkb/RU366022#function" }, { "database": "UniProtKB", "id": "A0AAA9T663", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T663#function" }, { "database": "UniProtKB", "id": "A0A3Q1LKH7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKH7#function" }, { "database": "UniProtKB", "id": "A0A3Q1LM92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM92#function" }, { "database": "UniProtKB", "id": "A0A3Q1LXA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXA9#function" }, { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7#function" }, { "database": "UniProtKB", "id": "A0ABZ3NNI4", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ATG7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7", "locus": { "chromosome": "22", "start_pos": 55578993, "end_pos": 55304487, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000035827", "url": "https://www.ensembl.org/id/ENSBTAG00000035827" } ] } } ], "crossref": [ { "id": "E1BNN7", "url": "https://alphafold.ebi.ac.uk/entry/E1BNN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000035827", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000035827", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01486", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01486", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "787967", "url": "https://www.ncbi.nlm.nih.gov/gene/787967", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042522", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042522", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:787967", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787967", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RQIWDAI", "url": "https://omabrowser.org/oma/group/RQIWDAI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LJG2", "url": "https://www.orthodb.org/?gene=A0A3Q1LJG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LXA9", "url": "https://www.orthodb.org/?gene=A0A3Q1LXA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BNN7", "url": "https://www.orthodb.org/?gene=E1BNN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10953", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10953", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10953:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10953:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00899", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00899", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16420", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16420", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001136439", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001136439", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJG2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKH7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM92-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LXA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LXA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N3C3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N3C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3C3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T663", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T663", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T663-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T663-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKJ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABZ3NNI4", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABZ3NNI4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNN7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAMGDLGLSRLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSVGLPARLTLEFSAFDMSAPTPARCCPAVGILYNTNTLEAFKAADKKLLLEEAANEIWESIKSGAALDNPVLLNKFLLLTFADLKKYHFYYWFCSPALCLPESIPLIQGPVALDQWFLPKQIQALEHAYDALCQTEGVPALPYFLIKYDETTVLVSSLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNLLVLAAHRWSGSFQSVEVVCFRDRTLQGVRDVTHSIVFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSAKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLAGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIDSHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPRHQGAGDLCPSYPMASADLLSSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETI", "length": 703, "header": "tr|E1BNN7-1|E1BNN7_BOVIN Isoform 1 of Ubiquitin-like modifier-activating enzyme ATG7 OS=Bos taurus OX=9913 GN=ATG7 PE=3 SV=2 CANONICAL=E1BNN7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJG2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN7/entry#A0A3Q1LJG2-1", "sequence": { "sequence": "MAAAMGDLGLSRLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSVGLPARLTLEFSAFDMSAPTPARCCPAVGILYNTNTLEAFKAADKKLLLEEAANEIWESIKSGAALDNPVLLNKFLLLTFADLKKYHFYYWFCSPALCLPESIPLIQGPVALDQWFLPKQIQALEHAYDALCQTEGVPALPYFLIKYDETTVLVSSLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNLLVLAAHRWSGSFQSVEVVCFRDRTLQGVRDVTHSIVFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSAKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLAGGKPKALAAADRLQKIFPGVLVINAALGFDTFVVMRHGLKKPRHQGAGDLCPSYPMASADLLSSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETI", "length": 638, "header": "tr|A0A3Q1LJG2-1|E1BNN7_BOVIN Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme ATG7 OS=Bos taurus OX=9913 GN=ATG7 PE=3 SV=2 CANONICAL=E1BNN7-1" }, "locus": { "chromosome": "22", "start_pos": 55577989, "end_pos": 55327027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079362.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079362.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059555.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059555.2" } ] } }, { "isoform_ac": "A0A3Q1LKH7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN7/entry#A0A3Q1LKH7-1", "sequence": { "sequence": "MAAAMGDLGLSRLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSVGLPARLTLEFSAFDMSAPTPARCCPAVGILYNTNTLEAFKAADKKLLLEEAANEIWESIKSGAALDNPVLLNKFLLLTFADLKKYHFYYWFCSPALCLPESIPLIQGPVALDQWFLPKQIQALEHAYDALCQTEGVPALPYFLIKYDETTVLVSSLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNLLVLAAHRWSGSFQSVEVVCFRDRTLQGVRDVTHSIVFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSAKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLAGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIDSHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPRHQGAGDLCPSYPMASADLLSSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETI", "length": 676, "header": "tr|A0A3Q1LKH7-1|E1BNN7_BOVIN Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme ATG7 OS=Bos taurus OX=9913 GN=ATG7 PE=3 SV=1 CANONICAL=E1BNN7-1" }, "locus": { "chromosome": "22", "start_pos": 55577989, "end_pos": 55327027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077885.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077885.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057168.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057168.2" } ] } }, { "isoform_ac": "A0A3Q1LM92-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN7/entry#A0A3Q1LM92-1", "sequence": { "sequence": "MAAAMGDLGLSRLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSVGLPARLTLEFSAFDMSAPTPARCCPAVGILYNTNTLEAFKAADKKLLLEEAANEIWESIKSGAALDNPVLLNKFLLLTFADLKKYHFYYWFCSPALCLPESIPLIQGPVALDQWFLPKQIQALEHAYDALCQTEGVPALPYFLIKYDETTVLVSSLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNLLVLAAHRWSGSFQSVEVVCFRDRTLQGVRDVTHSIVFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSAKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLAGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIDSHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPRHQGAGDLCPSYPMASADLLSSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAENAYQQTSWQQESLSCLCCST", "length": 713, "header": "tr|A0A3Q1LM92-1|E1BNN7_BOVIN Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme ATG7 OS=Bos taurus OX=9913 GN=ATG7 PE=3 SV=2 CANONICAL=E1BNN7-1" }, "locus": { "chromosome": "22", "start_pos": 55456780, "end_pos": 55327027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068166.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068166.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060988.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060988.2" } ] } }, { "isoform_ac": "A0A3Q1LXA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN7/entry#A0A3Q1LXA9-1", "sequence": { "sequence": "MAAAMGDLGLSRLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSVGLPARLTLEFSAFDMSAPTPARCCPAVGILYNTNTLEAFKAADKKLLLEEAANEIWESIKSGAALDNPVLLNKFLLLTFADLKKYHFYYWFCSPALCLPESIPLIQGPVALDQWFLPKQIQALEHAYDALCQTEGVPALPYFLIKYDETTVLVSSLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNLLVLAAHRWSGSFQSVEVVCFRDRTLQGVRDVTHSIVFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSAKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLAGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIDSHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPRHQGAGDLCPSYPMASADLLSSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAENRAILDTDYPVPPVKRQAPNGQSA", "length": 717, "header": "tr|A0A3Q1LXA9-1|E1BNN7_BOVIN Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme ATG7 OS=Bos taurus OX=9913 GN=ATG7 PE=3 SV=1 CANONICAL=E1BNN7-1" }, "locus": { "chromosome": "22", "start_pos": 55469065, "end_pos": 55327027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077815.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077815.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061833.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061833.1" } ] } }, { "isoform_ac": "A0A3Q1N3C3-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN7/entry#A0A3Q1N3C3-1", "sequence": { "sequence": "MAAAMGDLGLSRLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSVGLPARLTLEFSAFDMSAPTPARCCPAVGILYNTNTLEAFKAADKKLLLEEAANEIWESIKSGAALDNPVLLNKFLLLTFADLKKYHFYYWFCSPALCLPESIPLIQGPVALDQWFLPKQIQALEHAYDALCQTEGVPALPYFLIKYDETTVLVSSLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNLLVLAAHRWSGSFQSVEVVCFRDRTLQGVRDVTHSIVFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSAKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLAGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIDSHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPRHQGAGDLCPSYPMASADLLSSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQWWCFMSTRRGSWAAEW", "length": 641, "header": "tr|A0A3Q1N3C3-1|E1BNN7_BOVIN Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme ATG7 OS=Bos taurus OX=9913 GN=ATG7 PE=3 SV=2 CANONICAL=E1BNN7-1" }, "locus": { "chromosome": "22", "start_pos": 55393044, "end_pos": 55327027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076021.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076021.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063946.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063946.2" } ] } }, { "isoform_ac": "A0AAA9T663-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN7/entry#A0AAA9T663-1", "sequence": { "sequence": "MAAAMGDLGLSRLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSVGLPARLTLEFSAFDMSAPTPARCCPAVGILYNTNTLEAFKAADKKLLLEEAANEIWESIKSGAALDNPVLLNKFLLLTFADLKKYHFYYWFCSPALCLPESIPLIQGPVALDQWFLPKQIQALEHAYDALCQTEGVPALPYFLIKYDETTVLVSSLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNLLVLAAHRWSGSFQSVEVVCFRDRTLQGVRDVTHSIVFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSAKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLAGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIDSHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPRHQGAGDLCPSYPMASADLLSSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEKTLVLQTCRFPAPTPSSSLILHRHQPGVLQLSSILTPRLPGGSIRSHSCAGS", "length": 745, "header": "tr|A0AAA9T663-1|E1BNN7_BOVIN Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme ATG7 OS=Bos taurus OX=9913 GN=ATG7 PE=3 SV=1 CANONICAL=E1BNN7-1" }, "locus": { "chromosome": "22", "start_pos": 55547865, "end_pos": 55327027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104794.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104794.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093358.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093358.1" } ] } }, { "isoform_ac": "A0AAA9TKJ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN7/entry#A0AAA9TKJ6-1", "sequence": { "sequence": "MAAAMGDLGLSRLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSVGLPARLTLEFSAFDMSAPTPARCCPAVGILYNTNTLEAFKAADKKLLLEEAANEIWESIKSGAALDNPVLLNKFLLLTFAIQALEHAYDALCQTEGVPALPYFLIKYDETTVLVSSLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNLLVLAAHRWSGSFQSVEVVCFRDRTLQGVRDVTHSIVFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSAKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLAGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIDSHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPRHQGAGDLCPSYPMASADLLSSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKIWDMSDDETI", "length": 623, "header": "tr|A0AAA9TKJ6-1|E1BNN7_BOVIN Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme ATG7 OS=Bos taurus OX=9913 GN=ATG7 PE=3 SV=1 CANONICAL=E1BNN7-1" }, "locus": { "chromosome": "22", "start_pos": 55577989, "end_pos": 55327027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116288.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116288.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098919.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098919.1" } ] } }, { "isoform_ac": "A0ABZ3NNI4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN7/entry#A0ABZ3NNI4-1", "sequence": { "sequence": "MAAAMGDLGLSRLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSVGLPARLTLEFSAFDMSAPTPARCCPAVGILYNTNTLEAFKAADKKLLLEEAANEIWESIKSGAALDNPVLLNKFLLLTFADLKKYHFYYWFCSPALCLPESIPLIQGPVALDQWFLPKQIQALEHAYDALCQTEGVPALPYFLIKYDETTVLVSSLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNLLVLAAHRWSGSFQSVEVVCFRDRTLQGVRDVTHSIVFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSAKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLAGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIDSHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPRHQGAGDLCPSYPMASADLLSSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGYGDFCHGLITSFLSAWPLTNARLVLPKFSISMNEKDLISWRRCLILRTPS", "length": 650, "header": "tr|A0ABZ3NNI4-1|A0ABZ3NNI4_BOVIN Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme ATG7 OS=Bos taurus OX=9913 GN=ATG7 PE=3 SV=1 CANONICAL=E1BNN7-1" }, "locus": { "chromosome": "22", "start_pos": 55454198, "end_pos": 55327027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000050314.6", "url": "https://www.ensembl.org/id/ENSBTAT00000050314.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047028.5", "url": "https://www.ensembl.org/id/ENSBTAP00000047028.5" } ] } }, { "isoform_ac": "E1BNN7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN7/entry#E1BNN7-1", "sequence": { "sequence": "MAAAMGDLGLSRLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSVGLPARLTLEFSAFDMSAPTPARCCPAVGILYNTNTLEAFKAADKKLLLEEAANEIWESIKSGAALDNPVLLNKFLLLTFADLKKYHFYYWFCSPALCLPESIPLIQGPVALDQWFLPKQIQALEHAYDALCQTEGVPALPYFLIKYDETTVLVSSLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNLLVLAAHRWSGSFQSVEVVCFRDRTLQGVRDVTHSIVFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSAKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLAGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIDSHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPRHQGAGDLCPSYPMASADLLSSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETI", "length": 703, "header": "tr|E1BNN7-1|E1BNN7_BOVIN Isoform 1 of Ubiquitin-like modifier-activating enzyme ATG7 OS=Bos taurus OX=9913 GN=ATG7 PE=3 SV=2 CANONICAL=E1BNN7-1" }, "locus": { "chromosome": "22", "start_pos": 55577989, "end_pos": 55327027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043980.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043980.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041507.3", "url": "https://www.ensembl.org/id/ENSBTAP00000041507.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 76, "start_aa": "Thr", "end_pos": 76, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr76", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:787967", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787967", "resource": "KEGG Pathway" }, { "id": "R-BTA-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1632852", "resource": "Reactome", "description": "Macroautophagy" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BS20-1", "protein_name": "Ubiquitin-like modifier-activating enzyme ATG7", "gene_name": "ATG7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAMGDPALCKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKNIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPATGTLYNTNTLEAFKAADKKLLLEQAANEIWESIKSGAALDNPVLLNKFLLLTFADLKKYHFYYWFCSPALCLPESIPLVQGPVGLDQRFSPKQIQDLERAYDNLCQTEGVPALPYFLIKYDENTVLVSLLKHYSDFFQSQRTKVTIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVLCFRDRTLQGVRDIAHSIIFEVKLPEVAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLVGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNSSSITLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSNPVTSADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETV", "length": 703 }, "evidence": [ { "id": "E1BNN7", "url": "https://omabrowser.org/oma/group/E1BNN7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1A851-1", "protein_name": "Ubiquitin-like modifier-activating enzyme ATG7", "gene_name": "ATG7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAVSNESQNPVDPGSSKLQFAPFSSALNVGFWHELTQKKLNEYRLDETPKVIKGYYYNGDPSGFPARLTLEYSAFDINASIPARCCPAFGTLYNTNTFETFKSCDKKSLLEKEANEIWESIKSGAALENPMLLNRFLLLTFADLKKYHFYYWFCYPALCFPDGIHVIQKPVCLGDRFSLNQIQALQKAYDELCQTEGVTAFPYFLIKYHDNSVVVSPLKKWDGFFQDQGGKVTVGVYDPCNLSHYPGWPLRNFLILASHKWGNILQSIEVLCFRDRTMQGVRDITHSIIFEIKLPQGAFGPDCPKAVGWEKNQKGGMGPRVVNLSECMDPKRFAESSVDLNLKLMCWRLVPTLDLEKIVSAKCLLLGAGTLGCSVARTLMGWGVRKITFVDNARISYSNPVRQPLYEFEDCLSGGKPKALAAAERLQKIFPGVNSEGYNMSIPMPGHPVNFSEVTMAQARKDVATLEELIDAHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQETGNACFNTAPGPSDLLGSSLFSNIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAVASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAETVQSKSICLKVVFNNDL", "length": 716 }, "evidence": [ { "id": "E1BNN7", "url": "https://omabrowser.org/oma/group/E1BNN7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O95352-1", "protein_name": "Ubiquitin-like modifier-activating enzyme ATG7", "gene_name": "ATG7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETI", "length": 703 }, "evidence": [ { "id": "E1BNN7", "url": "https://omabrowser.org/oma/group/E1BNN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P38862-1", "protein_name": "Ubiquitin-like modifier-activating enzyme ATG7", "gene_name": "ATG7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSERVLSYAPAFKSFLDTSFFQELSRLKLDVLKLDSTCQPLTVNLDLHNIPKSADQVPLFLTNRSFEKHNNKRTNEVPLQGSIFNFNVLDEFKNLDKQLFLHQRALECWEDGIKDINKCVSFVIISFADLKKYRFYYWLGVPCFQRPSSTVLHVRPEPSLKGLFSKCQKWFDVNYSKWVCILDADDEIVNYDKCIIRKTKVLAIRDTSTMENVPSALTKNFLSVLQYDVPDLIDFKLLIIRQNEGSFALNATFASIDPQSSSSNPDMKVSGWERNVQGKLAPRVVDLSSLLDPLKIADQSVDLNLKLMKWRILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYNFEDCGKPKAELAAASLKRIFPLMDATGVKLSIPMIGHKLVNEEAQHKDFDRLRALIKEHDIIFLLVDSRESRWLPSLLSNIENKTVINAALGFDSYLVMRHGNRDEQSSKQLGCYFCHDVVAPTDSLTDRTLDQMCTVTRPGVAMMASSLAVELMTSLLQTKYSGSETTVLGDIPHQIRGFLHNFSILKLETPAYEHCPACSPKVIEAFTDLGWEFVKKALEHPLYLEEISGLSVIKQEVERLGNDVFEWEDDESDEIA", "length": 630 }, "evidence": [ { "id": "E1BNN7", "url": "https://omabrowser.org/oma/group/E1BNN7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q641Y5-1", "protein_name": "Ubiquitin-like modifier-activating enzyme ATG7", "gene_name": "Atg7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDPGLSKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSAPTPARCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVGLDQRLSPKQIQALEHAYDDLCRTEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKLTVGVYDPCNLTQHPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNASGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEELIDSHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEQEGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV", "length": 698 }, "evidence": [ { "id": "E1BNN7", "url": "https://omabrowser.org/oma/group/E1BNN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86CR9-1", "protein_name": "Ubiquitin-like modifier-activating enzyme atg7", "gene_name": "atg7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTNTLQFKEFSSFVNISFWHELSNKKLDELKLSEESIPLNGHYTFSPSQQLDPFLCLEFNAFLRNNVTNSTENQYVLPPRSYLSHGTLYNYNTVDDFKQSPKIKLFNDASKRIWNDINNGNIDKDTSLLNRFILLTYADIKNHQFYYMFGIPALLPSQPIQQFTEKPESINIESLKSFSNQILPQYFCLKQQQQESSTTTTTSFELIGSIEEKGNQYLNECLENDLIPLVGFCDPCSLPLNPGWPLRNFLIYLSIKYPMLKKIKVLCYRGNGSTSNSILLSLELPSMGEQLIKKQQEEDAGEWSGKSVGWEKDSNGKIAPRFVSLASTMDPLKLAEQSVDLNLKLMRWRVMPSLELEKIKTTSCLLLGSGTLGCNVARSLMSWGVRNITFVDSSKVSYSNPVRQSLFTFADCSPKAKEKSIAAADALKKIFPAINANAHVFSIPMPGHSVPQSEYQSIRNTIELLENLIKQHDVIYLLTDSRESRWLPTMLSRAHGKLCINAALGFDSYLVIRHGIKDQCQNELNPSISSKLGYQGSDLGCYFCNDVIAPTDTLKDRTLDQMCTVTRPGLSMMASSIAVELLISTIHHPYGGRAKGETETDVYVQGSTPLGIIPHQLRGFISHYQTLPLFSNPYKHCTACSDYIIDEYNSKGFDFIINVMNDSSCLTKICGIDDLKNTEVNIDWDIDISDDDDDNNNNNNKEKNDDF", "length": 707 }, "evidence": [ { "id": "E1BNN7", "url": "https://omabrowser.org/oma/group/E1BNN7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q94CD5-1", "protein_name": "Ubiquitin-like modifier-activating enzyme atg7", "gene_name": "ATG7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEKETPAIILQFAPLNSSVDEGFWHSFSSLKLDKLGIDDSPISITGFYGPCGHPQVSNHLTLLSESLPLDEQSLIASTSHGNRNKCPVPGILYNTNTVESFNKLDKQSLLKAEANKIWEDIQSGKALEDPSVLPRFLVISFADLKKWSFRYWFAFPAFVLDPPVSLIELKPASEYFSSEEAESVSAACNDWRDSDLTTDVPFFLVSVSSDSKASIRHLKDLEACQGDHQKLLFGFYDPCHLPSNPGWPLRNYLALIRSRWNLETVWFFCYRESRGFADLNLSLVGQASITLSSGESAETVPNSVGWELNKGKRVPRSISLANSMDPTRLAVSAVDLNLKLMRWRALPSLNLNVLSSVKCLLLGAGTLGCQVARTLMGWGIRNITFVDYGKVAMSNPVRQSLYNFEDCLGRGEFKAVAAVKSLKQIFPAMETSGVVMAIPMPGHPISSQEEDSVLGDCKRLSELIESHDAVFLLTDTRESRWLPSLLCANANKIAINAALGFDSYMVMRHGAGPTSLSDDMQNLDINKTNTQRLGCYFCNDVVAPQDSMTDRTLDQQCTVTRPGLAPIAGALAVELLVGVLQHPLGINAKGDNSSLSNTGNNDDSPLGILPHQIRGSVSQFSQITLLGQASNSCTACSETVISEYRERGNSFILEAINHPTYLEDLTGLTELKKAANSFNLDWEDDDTDDDDVAVDL", "length": 697 }, "evidence": [ { "id": "E1BNN7", "url": "https://omabrowser.org/oma/group/E1BNN7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9D906-1", "protein_name": "Ubiquitin-like modifier-activating enzyme ATG7", "gene_name": "Atg7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV", "length": 698 }, "evidence": [ { "id": "E1BNN7", "url": "https://omabrowser.org/oma/group/E1BNN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 18, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "response to nutrient levels", "id": "GO:0031667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031667", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "regulation of primary metabolic process", "id": "GO:0080090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080090", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "positive regulation of catabolic process", "id": "GO:0009896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009896", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "cellular response to hyperoxia", "id": "GO:0071455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071455", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "protein modification by small protein conjugation", "id": "GO:0032446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032446", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ubiquitin-like modifier activating enzyme activity", "id": "GO:0008641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008641", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "Atg12 activating enzyme activity", "id": "GO:0019778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019778", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" }, { "name": "Atg8 activating enzyme activity", "id": "GO:0019779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019779", "evidence": [ { "database": "UniProtKB", "id": "E1BNN7", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 670, "end_pos": 672, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNN7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 703, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNN7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNN7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" }, { "id": "PF00899", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00899" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "THIF-type NAD/FAD binding fold", "eco_id": "ECO_0000259", "start_pos": 338, "end_pos": 600, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNN7" }, { "id": "PF16420", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16420" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like modifier-activating enzyme Atg7 N-terminal", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 323, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 76 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 318, "end_pos": 320 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 445, "end_pos": 447 }, { "start_pos": 670, "end_pos": 672 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLQ1-1", "uniprot_ac": "E1BLQ1", "uniprot_id": "E1BLQ1_BOVIN", "mass": { "chemical_mass": 72883.0, "monoisotopic_mass": 72883.0 }, "refseq": { "ac": "XP_005218150", "name": "BLOC-3 complex member HPS4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218150" }, "gene_names": [ { "name": "HPS4", "type": "recommended", "evidence": [ { "id": "E1BLQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ] }, { "name": "HPS4", "type": "synonym", "evidence": [ { "id": "XP_005218150", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218150" } ] } ], "protein_names": [ { "name": "BLOC-3 complex member HPS4", "type": "synonym", "evidence": [ { "id": "XP_005218150", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218150" } ] }, { "name": "HPS4 biosis of lysosomal organelles complex 3 subunit 2", "type": "synonym", "evidence": [ { "id": "E1BLQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HPS4", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1", "locus": { "chromosome": "17", "start_pos": 66113315, "end_pos": 66140520, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017038", "url": "https://www.ensembl.org/id/ENSBTAG00000017038" } ] } } ], "crossref": [ { "id": "E1BLQ1", "url": "https://alphafold.ebi.ac.uk/entry/E1BLQ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017038", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017038", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "615386", "url": "https://www.ncbi.nlm.nih.gov/gene/615386", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:615386", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615386", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YACCSPV", "url": "https://omabrowser.org/oma/group/YACCSPV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BLQ1", "url": "https://www.orthodb.org/?gene=E1BLQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14407", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14407", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14407:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14407:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005218150", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218150", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N720", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N720", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N720-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N720-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMM9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMM9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUP4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUP4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLQ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASTSTESKLASWWNYFFLYDGSQVKGEEDPTRAGICYFYPPQTLLDQQELLCGQIAGVVHCVSHISGSPPALVRLRKLKFAVKVDGDYLWVLGCAAELPDVSCRQLLHRLVGFFHFCNGPVSLACKSCPREELRSEWDTLIEHILGNTGDLHKIFNCLWHLDQTKVEALLLLKAALILQTCQRAPHVLAGCILYAGLIVSTQLPPSVTAKVLLHRMARRDQRKPTGGDALQERGVVLPPNVQITPVFLTEEEAASLREFPREPSASAPAPPARLQEPSAAPKENAPGHAGSKAQTSTTTPEPPSPDAALADGSRGHGHWSGPDLKSTPPALQHCTAAGKGSALFVGNGHLDLSEIHIPEAQKTEASPGHPAADGGGPGCEESVHNPGSPEAKPPGVLSLGRLPASAPEVVPQNGALEQPADLPGDGSQAPIPRKDHVPSRTSGPGRAPCLDLRQKNTEQPLEEHGGEQRHSGAPEGCLTPGPDSTDPSDEGPSANRTASRVSPASREGLVRMNLYTHSVKGLVLSLLAEEPLLGDRVAVEEVYHGSLASLNGLEVHLSETLPRDQAAPAARTYSFAHYDRVQNLLTANLPQVTTAQDRRFLQAVSLMHSEFARLPTLYEVTVRNASTAVYACCNPVQETYFQQLATAVRSSGFPNPQDGAFGLPGKAKQKLLKHGVNLL", "length": 681, "header": "tr|E1BLQ1-1|E1BLQ1_BOVIN Isoform 1 of HPS4 biosis of lysosomal organelles complex 3 subunit 2 OS=Bos taurus OX=9913 GN=HPS4 PE=4 SV=2 CANONICAL=E1BLQ1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N720-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1/entry#A0A3Q1N720-1", "sequence": { "sequence": "MAASTSTESKLASWWNYFFLYDGSQVKGEEDPTRAGICYFYPPQTLLDQQELLCGQIAGVVHCVSHISGSPPALVRLRKLKFAVKVDGDYLWSCPREELRSEWDTLIEHILGNTGDLHKIFNCLWHLDQTKVEALLLLKAALILQTCQRAPHVLAGCILYAGLIVSTQLPPSVTAKVLLHRMARRDQRKPTGGDALQERGVVLPPNVQITPVFLTEEEAASLREFPREPSASAPAPPARLQEPSAAPKENAPGHAGSKAQTSTTTPEPPSPDAALADGSRGHGHWSGPDLKSTPPALQHCTAAGKGSALFVGNGHLDLSEIHIPEAQKTEASPGHPAADGGGPGCEESVHNPGSPEAKPPGVLSLGRLPASAPEVVPQNGALEQPADLPGDGSQAPIPRKDHVPSRTSGPGRAPCLDLRQKNTEQPLEEHGGEQRHSGAPEGCLTPGPDSTDPSDEGPSANRTASRVSPASREGLVRMNLYTHSVKGLVLSLLAEEPLLGDRVAVEEVYHGSLASLNGLEVHLSETLPRDQAAPAARTYSFAHYDRVQNLLTANLPQVTTAQDRRFLQAVSLMHSEFARLPTLYEVTVRNASTAVYACCNPVQETYFQQLATAVRSSGFPNPQDGAFGLPGKAKQKLLKHGVNLL", "length": 645, "header": "tr|A0A3Q1N720-1|E1BLQ1_BOVIN Computationally mapped isoform of HPS4 biosis of lysosomal organelles complex 3 subunit 2 OS=Bos taurus OX=9913 GN=HPS4 PE=4 SV=2 CANONICAL=E1BLQ1-1" }, "locus": { "chromosome": "17", "start_pos": 66138584, "end_pos": 66114319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071404.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071404.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066389.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066389.2" } ] } }, { "isoform_ac": "A0AAA9SMM9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1/entry#A0AAA9SMM9-1", "sequence": { "sequence": "MAASTSTESKLASWWNYFFLYDGSQVKGEEDPTRAGICYFYPPQTLLDQQELLCGQIAGVVHCVSHISGSPPALVRLRKLKFAVKVDGDYLWVLGCAAELPDVSCRQLLHRLVGFFHFCNGPVSLACKSCPREELRSEWDTLIEHILGNTGDLHKIFNCLWHLDQTKVEALLLLKAALILQTCQRAPHVLAGCILYAGLIVSTQLPPSVTAKVLLHRMARRDQRKPTGGDALQERGVVLPPNVQITPVFLTEEEAASLREFPREPSASAPAPPARLQEPSAAPKENAPGHAGSKAQTSTTTPEPPSPDAALADGSRGHGHWSGPDLKSTPPALQHCTAADGGGPGCEESVHNPGSPEAKPPGVLSLGRLPASAPEVVPQNGALEQPADLPGDGSQAPIPRKDHVPSRTSGPGRAPCLDLRQKNTEQPLEEHGGEQRHSGAPEGCLTPGPDSTDPSDEGPSANRTASRVSPASREGLVRMNLYTHSVKGLVLSLLAEEPLLGDRVAVEEVYHGSLASLNGLEVHLSETLPRDQAAPAARTYSFAHYDRVQNLLTANLPQVTTAQDRRFLQAVSLMHSEFARLPTLYEVTVRNASTAVYACCNPVQETYFQQLATAVRSSGFPNPQDGAFGLPGKAKQKLLKHGVNLL", "length": 646, "header": "tr|A0AAA9SMM9-1|E1BLQ1_BOVIN Computationally mapped isoform of HPS4 biosis of lysosomal organelles complex 3 subunit 2 OS=Bos taurus OX=9913 GN=HPS4 PE=4 SV=1 CANONICAL=E1BLQ1-1" }, "locus": { "chromosome": "17", "start_pos": 66138584, "end_pos": 66114319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124648.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124648.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086562.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086562.1" } ] } }, { "isoform_ac": "A0AAA9SUP4-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1/entry#A0AAA9SUP4-1", "sequence": { "sequence": "MAASTSTESKLASWWNYFFLYDGSQVKGEEDPTRAGICYFYPPQTLLDQQELLCGQIAGVVHCVSHISGSPPALVRLRKLKFAVKVDGDYLWVLGCAAELPDVSCRQLLHRLVGFFHFCNGPVSLACKSCPREELRSEWDTLIEHILGNTGDLHKIFNCLWHLDQTKVEALLLLKAALILQTCQRAPHVLAGCILYAGLIVSTQLPPSVTAKVLLHRMARRDQYHGSLASLNGLEVHLSETLPRDQAAPAARTYSFAHYDRVQNLLTANLPQVTTAQDRRFLQAVSLMHSEFARLPTLYEVTVRNASTAVYACCNPVQETYFQQLATAVRSSGFPNPQDGAFGLPGKAKQKLLKHGVNLL", "length": 360, "header": "tr|A0AAA9SUP4-1|E1BLQ1_BOVIN Computationally mapped isoform of HPS4 biosis of lysosomal organelles complex 3 subunit 2 OS=Bos taurus OX=9913 GN=HPS4 PE=4 SV=1 CANONICAL=E1BLQ1-1" }, "locus": { "chromosome": "17", "start_pos": 66138584, "end_pos": 66114319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124108.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124108.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086880.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086880.1" } ] } }, { "isoform_ac": "E1BLQ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1/entry#E1BLQ1-1", "sequence": { "sequence": "MAASTSTESKLASWWNYFFLYDGSQVKGEEDPTRAGICYFYPPQTLLDQQELLCGQIAGVVHCVSHISGSPPALVRLRKLKFAVKVDGDYLWVLGCAAELPDVSCRQLLHRLVGFFHFCNGPVSLACKSCPREELRSEWDTLIEHILGNTGDLHKIFNCLWHLDQTKVEALLLLKAALILQTCQRAPHVLAGCILYAGLIVSTQLPPSVTAKVLLHRMARRDQRKPTGGDALQERGVVLPPNVQITPVFLTEEEAASLREFPREPSASAPAPPARLQEPSAAPKENAPGHAGSKAQTSTTTPEPPSPDAALADGSRGHGHWSGPDLKSTPPALQHCTAAGKGSALFVGNGHLDLSEIHIPEAQKTEASPGHPAADGGGPGCEESVHNPGSPEAKPPGVLSLGRLPASAPEVVPQNGALEQPADLPGDGSQAPIPRKDHVPSRTSGPGRAPCLDLRQKNTEQPLEEHGGEQRHSGAPEGCLTPGPDSTDPSDEGPSANRTASRVSPASREGLVRMNLYTHSVKGLVLSLLAEEPLLGDRVAVEEVYHGSLASLNGLEVHLSETLPRDQAAPAARTYSFAHYDRVQNLLTANLPQVTTAQDRRFLQAVSLMHSEFARLPTLYEVTVRNASTAVYACCNPVQETYFQQLATAVRSSGFPNPQDGAFGLPGKAKQKLLKHGVNLL", "length": 681, "header": "tr|E1BLQ1-1|E1BLQ1_BOVIN Isoform 1 of HPS4 biosis of lysosomal organelles complex 3 subunit 2 OS=Bos taurus OX=9913 GN=HPS4 PE=4 SV=2 CANONICAL=E1BLQ1-1" }, "locus": { "chromosome": "17", "start_pos": 66138584, "end_pos": 66114319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053508.4", "url": "https://www.ensembl.org/id/ENSBTAT00000053508.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050301.2", "url": "https://www.ensembl.org/id/ENSBTAP00000050301.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:615386", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615386", "resource": "KEGG Pathway" }, { "id": "R-BTA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I8P4-1", "protein_name": "Hermansky-Pudlak syndrome 4 protein isoform X1", "gene_name": "Hps4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATPTPSEIKSASWWNYFFLYDGSKVKGEGDPTRAGICYFYPSKTLLDQQELLCGQLAGVVRCLWDLSGTPPTLIRLRKLKFAIRVDGDYLWALGCGVELSDVSCRQFLDQLIGFFHFYMGPVSLAYKSRSQEELSLQWDTFITQVLRGTSESHRIFNALWNLDHTKVEPLLLLKAALILQTCQRSPHVLAGCILYKGLIVNSQLPPSLTAKVLLYQTAPEDQRLPGAGAPQQEAGAALPPNVQITPVFLSEEEVASLHEFTVEQKTRLQESSSQYPPWDRSTPTRAEDAWTSATILEPTPHDGAWLNGRGADGHLLGHEQQEHAAAAGLCATACGPGSGSSSSSLQQELGFSQEELDLSEIHISEAQEAFSPAPALGDQEAVFTSHQAPTLPEDTAVCSCLDPSPLERLPESRGLERLTDLPISNGQTQVPGMDPLPRRSSRPAVLPPQDPGAEQYRDGSHEHRSALACTLYSGDSRGPSTPADRIGFAPSPAGPYAGLLPMNLYTHSVNGLVLSLLGEEPLLRDTAAIEEVYHSSLASLNGLEVHLKETLPRDEACPTSSTYSFVHYDRIQSMLTANLSLVAAPQDRRFLQAINLVHSDFAQLPTLYEMTVRNASTAVYACCNPAQETYFQQLTPTTRSSGFPNPQDCAFSLAGKAKRKLLKHGVNLL", "length": 670 }, "evidence": [ { "id": "E1BLQ1", "url": "https://omabrowser.org/oma/group/E1BLQ1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8J8YPH6-1", "protein_name": "HPS4, biogenesis of lysosomal organelles complex 3 subunit 2", "gene_name": "Hps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFCSLARWNYFFLYDGSKVQGEGDPTRAGICYFYPSQTLLDQQELLCGQLAGVVRCLWDLSGTPPMLIRLRNLKFALRVDGDYLWALGCGVELSDASCRQFLDQLIGFFHFYMGPVSLAYKSHPQEELRLQWDTFITQVLRSTSESHRIFNALWNLDRTKVPTLLLMAFLSVCLTLRIVNSQLPPSLTAKVLLHHTVAADQRPPGAGAATQETGPALPPAVQITPVFLSEEEVASLHEFPVEHDPRLEESSFQCPPWDQSTPTGAEDAWTSATVLEPTPCGGGHSPRLEQERAGPTGLCTEACDRSSDLSGRLQRELCLSQELDLSAMHLSEAQDAFPPVPASCDLQALCVSRDTPTLPEDTAICSCLDPSPLERPPEGGSLEALADLPLTHGHTHVPGTEPLPSSRTMVLLPQHPEGVEPGVEPCGSGAQDRLPALARSSHSADSQGPSPSADRTGFNPSPSGPHAGLMPMNLYTHSVNGLVLSLLAKETLGSDTAAIEEVPTVLSHPPSDAVWTEVRCLHLLGPFQDHAAYPVSGLFIQYHSSLASLNGLEVHLKETLPRDETSPTGSTYNFLHYDRIQSVLSANLPLVAAPQNRRFLQAVNLMHSDFAQLPMLYEMTIRNASTAVYACSNPAQETYFQQLAPTARSSGFPNPQDCAFSLSGKAKQKLLKHGVNLL", "length": 680 }, "evidence": [ { "id": "E1BLQ1", "url": "https://omabrowser.org/oma/group/E1BLQ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZN81-1", "protein_name": "HPS4 biosis of lysosomal organelles complex 3 subunit 2", "gene_name": "HPS4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLETGLYLPLLDSLKAVPNDDHVGQSTDRPVPPQQVVVQCLAAVHHVEQGRRSICAVLALLEGGDGAVIVWSRHGHSLVTWGWDGVLLPRSLGADATPVLPVLPAPALRRPGRRGSSAWAAPVGHRHAWDTDTHGQRCNYFFLYDGSKVKEEGDPTSAGICYFYPSQTLPDQQELLCGQIAGVVHCMTEISGAPPSLIRLKKLKFAVIVDGDYLWVLGCAVDLPDISCRRFLEQLISLFTFYNGPVHQAYMEFSQEELNRLWDRYIEYIQKSTDDLHKIFNSLWNLDKTKVDPLLLLKAALILQTCQRSPHVLAGCIIYKGLIVSTQLPPPLTAKVLLQGSESSGQSEPGSEEQQEPDSPLPQGVRIVPVFLTEDEVSVLQVEWMNRSTTAPASPRGENNVLSSPAVSESTGIHINQDLNDISVLTEQASSTATPEDVVQSGSFANTVPLEGFPKMEARKRSSPTAELSSPGNERSELNRKPSFSSDGHVKELLSPSELRTAQYAQTMDSYLEGFSFPNPYAKEQESQSTQEFIVDSHVEQHSFQSCLADNASPTTCSAAQELSRRKSNEQEKQGTLSQNSVSAESDAAGDSWSLDCPTPVAQSELRSKSQPMAADVQEGLPSAPAENTDCTQSGEQEWPQAGRLAAQGAESDKHCKFTQMSLYVHSIKGLVLTLLAEDHFQDDRSSIEDVYHSSLASLNGLEVHLRETLPKDFLSSAKATYSFTHYDCIQNVLTANVSHPPGPLDRHFLRAATLIHSDFNRLPTVSEVIVRNASTAVYACRNPVQETYFQQLGAPLRNSGAPNPQDSAFSLPNKAKQKLLKHGVNLL", "length": 828 }, "evidence": [ { "id": "E1BLQ1", "url": "https://omabrowser.org/oma/group/E1BLQ1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q99KG7-1", "protein_name": "BLOC-3 complex member HPS4", "gene_name": "Hps4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTPPETKSAAWWNYFFLYDGSKVKGEGDPTRAGICYFYPPQTLLDQQELLCGQLAGVVRCLWDLSGTPPMLIRMRNLKFAIRADGDYLWALGCGVEISDASCRQFLDQLIGFFHFYMGPVSLAYKSHPQEELSLQWDTSITQVLRSTSESHRIFNALWNLDRTKVEPLLLLKAALILQTCQRSPHVLAGCILYKGLIVNSQLLPSLTAKVLLHQTVPADQRLPGAGAAPQETGAALPPDVQITSVFLSEEEVASLHEFPVEHETRLQGSSVQYPPWDQSSPTQAEDAWASAAIPEPTPHDGACPSGSGADERLPRLEQECAGPTGLCTTACGQGSGLSSRLQKELCLSREELDSSEMHVSEAQEAFPPLPALGDLETLHSSHSAPTLPEDTAICSCLHPCPLERLPESGRLGQLADLPLTNGQTQVPGTDPLPSSMPVALPPQHPVGVEPSVEPYGNGAQESHSALPRSSRSPDSPGPSPSADRTGFKPSPSGRHAGLVPMNLYTHSVNGLVLSLLAEETLLSDTAAIEEVYHSSLASLNGLEVHLKETLPRDEASLTSSTYNFLHYDRIQSVLSANLPLVTAPQDRRFLQAVNLMHSDFALLPMLYEMTIRNASTAVYACSSPAQETYFQQLAPTARSSGFPNPQDCAFSLAGKAKQKLLKHGVNLL", "length": 671 }, "evidence": [ { "id": "E1BLQ1", "url": "https://omabrowser.org/oma/group/E1BLQ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQG7-1", "protein_name": "BLOC-3 complex member HPS4", "gene_name": "HPS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGVVRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYNGPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARILQTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALPPNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGHVESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKELVFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDTAISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRGNKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVRMNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSSTYNFTHYDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYACCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL", "length": 708 }, "evidence": [ { "id": "E1BLQ1", "url": "https://omabrowser.org/oma/group/E1BLQ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "BLOC-3 complex", "id": "GO:0031085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031085", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "platelet dense granule", "id": "GO:0042827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042827", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "melanosome assembly", "id": "GO:1903232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903232", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "protein targeting", "id": "GO:0006605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "lysosome organization", "id": "GO:0007040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLQ1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 681, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLQ1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLQ1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" }, { "id": "PF19033", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCZ1/INTU/HPS4 third Longin", "eco_id": "ECO_0000259", "start_pos": 573, "end_pos": 671, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BLQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ1" }, { "id": "PF19031", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19031" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCZ1/INTU/HSP4 first Longin", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 121, "start_aa": "Trp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 497, "end_pos": 499 }, { "start_pos": 626, "end_pos": 628 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNR7-1", "uniprot_ac": "E1BNR7", "uniprot_id": "E1BNR7_BOVIN", "mass": { "chemical_mass": 64266.0, "monoisotopic_mass": 64266.0 }, "refseq": {}, "gene_names": [ { "name": "VANGL1", "type": "recommended", "evidence": [ { "id": "E1BNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNR7" } ] } ], "protein_names": [ { "name": "Vang-like protein", "type": "recommended", "evidence": [ { "id": "E1BNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNR7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNR7", "url": "https://www.uniprot.org/uniprotkb/E1BNR7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "VANGL1", "url": "https://www.uniprot.org/uniprotkb/E1BNR7", "locus": { "chromosome": "3", "start_pos": 27623362, "end_pos": 27677387, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005788", "url": "https://www.ensembl.org/id/ENSBTAG00000005788" } ] } } ], "crossref": [ { "id": "E1BNR7", "url": "https://alphafold.ebi.ac.uk/entry/E1BNR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005788", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005788", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "513056", "url": "https://www.ncbi.nlm.nih.gov/gene/513056", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HWLSRQW", "url": "https://omabrowser.org/oma/group/HWLSRQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNR7", "url": "https://www.orthodb.org/?gene=E1BNR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20886", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20886", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1NAN9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NAN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NAN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NAN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNR7", "url": "https://www.uniprot.org/uniprotkb/E1BNR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTESTYSGYSYYSSHSKKSHRQGLNLCKLAHHIGQNQNLTVRLCSVCAILLFSPETLGRTTPGERNRERHKSPRNKDGRGSEKSVTIQAPTGEPLLANDSARTEEAQDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCRRYLGLTVAAVLGLLVFLTPIAFILLPPILWRDELEPCGTICEGLFISVAFKLLILLIGTWALFFRKQRADMPRIFVFRALLLVLIFLFVVSYWLFYGVRILDSRDRNYQGIVQYAVSLVDALLFIHYLAVVLLELRQLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRRARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARALQKYLRTTRQQNYHSMESILQHLAFCITHSMTPKAFLERYLSAGPTLQYDRERWLSTQWRLVSDEAVTNGLRDGLVFVLKCLDFSLVVNVKKIPFIMLSEEFIDPKSHKFVLRLQSETSV", "length": 564, "header": "tr|E1BNR7-1|E1BNR7_BOVIN Isoform 1 of Vang-like protein OS=Bos taurus OX=9913 GN=VANGL1 PE=3 SV=4 CANONICAL=E1BNR7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NAN9-1", "url": "https://www.uniprot.org/uniprotkb/E1BNR7/entry#A0A3Q1NAN9-1", "sequence": { "sequence": "MDTESTYSGYSYYSSHSKKSHRQGERNRERHKSPRNKDGRGSEKSVTIQAPTGEPLLANDSARTEEAQDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCRRYLGLTVAAVLGLLVFLTPIAFILLPPILWRDELEPCGTICEGLFISVAFKLLILLIGTWALFFRKQRADMPRIFVFRALLLVLIFLFVVSYWLFYGVRILDSRDRNYQGIVQYAVSLVDALLFIHYLAVVLLELRQLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDAALMAKLELPVTDGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRRARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARALQKYLRTTRQQNYHSMESILQHLAFCITHSMTPKAFLERYLSAGPTLQYDRERWLSTQWRLVSDEAVTNGLRDGLVFVLKCLDFSLVVNVKKIPFIMLSEEFIDPKSHKFVLRLQSETSV", "length": 537, "header": "tr|A0A3Q1NAN9-1|E1BNR7_BOVIN Computationally mapped isoform of Vang-like protein OS=Bos taurus OX=9913 GN=VANGL1 PE=3 SV=1 CANONICAL=E1BNR7-1" }, "locus": { "chromosome": "3", "start_pos": 27665875, "end_pos": 27624366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066611.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066611.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068348.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068348.2" } ] } }, { "isoform_ac": "E1BNR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNR7/entry#E1BNR7-1", "sequence": { "sequence": "MDTESTYSGYSYYSSHSKKSHRQGLNLCKLAHHIGQNQNLTVRLCSVCAILLFSPETLGRTTPGERNRERHKSPRNKDGRGSEKSVTIQAPTGEPLLANDSARTEEAQDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCRRYLGLTVAAVLGLLVFLTPIAFILLPPILWRDELEPCGTICEGLFISVAFKLLILLIGTWALFFRKQRADMPRIFVFRALLLVLIFLFVVSYWLFYGVRILDSRDRNYQGIVQYAVSLVDALLFIHYLAVVLLELRQLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRRARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARALQKYLRTTRQQNYHSMESILQHLAFCITHSMTPKAFLERYLSAGPTLQYDRERWLSTQWRLVSDEAVTNGLRDGLVFVLKCLDFSLVVNVKKIPFIMLSEEFIDPKSHKFVLRLQSETSV", "length": 564, "header": "tr|E1BNR7-1|E1BNR7_BOVIN Isoform 1 of Vang-like protein OS=Bos taurus OX=9913 GN=VANGL1 PE=3 SV=4 CANONICAL=E1BNR7-1" }, "locus": { "chromosome": "3", "start_pos": 27665875, "end_pos": 27624366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007608.6", "url": "https://www.ensembl.org/id/ENSBTAT00000007608.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007608.6", "url": "https://www.ensembl.org/id/ENSBTAP00000007608.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A7P7-1", "protein_name": "Vang-like protein", "gene_name": "VANGL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDTESTYSGYSHYSGHSKKAHRQGSRDRHKSPRSKDGSRSEKSVTIQTPPAEPLLGNDASRTEEGQDDNWGETTTAITGTSEHSISQEDIARISKDLEDSVGLDCKRYLGLTVAAVLGLLVFLTPIAFILLPQILWRDDLEPCGTVCEGLFISVAFKLLILLIGTWALFFRQPKADIPRVFVFRALLLVLIFLFVFSYWLFYGVRILDSKDTNYQGIVQYAVSLVDALLFIHYLAIVLLELRQLQPMFTVKVVRSTDGESRYYSLGHLSIQRAALVVLENYYRDFPVYNPALLTASKSRAAKHMAGLKVYNVDGPGNNASGQSRAMIAAAARRRDSSHNELYYEEADHERRVKKRRARLVVAVEEAFTHIKRLQTEEQQKAPGEMMDSREAAQAIFPSMARALQKYLRTTRQQQYHSMESILQHLSFCITNNMTPKAFLERYLSPGPTLQYDRDRWFSKQWTLVSEEAVTSGLQDGIVFVLKCLDFSLVANVKKIPFIKLSEEFIDPKSHKFVLRLQSETSV", "length": 522 }, "evidence": [ { "id": "E1BNR7", "url": "https://omabrowser.org/oma/group/E1BNR7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q80Z96-1", "protein_name": "Vang-like protein 1", "gene_name": "Vangl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTESTYSGYSYYSSHSKKSHRQGERTRERHKSPRNKDGRGSEKSVTIQAPAGEPLLANDSARTGAEEVQDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCKRYLGLTVASFLGLLVFLTPIAFILLPQILWREELKPCGAICEGLLISVSFKLLILLIGTWALFFRKQRADVPRVFVFRALLLVLIFLFVVSYWLFYGVRILDSRDQNYKDIVQYAVSLVDALLFIHYLAIVLLELRQLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRRARLVVAVEEAFIHIQRLQAEEQQKSPGEVMDPREAAQAIFPSMARALQKYLRTTRQQHYHSMESILQHLAFCITNSMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLISEEAVTNGLRDGIVFVLKCLDFSLVVNVKKIPFIVLSEEFIDPKSHKFVLRLQSETSV", "length": 526 }, "evidence": [ { "id": "E1BNR7", "url": "https://omabrowser.org/oma/group/E1BNR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TAA9-1", "protein_name": "Vang-like protein 1", "gene_name": "VANGL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTESTYSGYSYYSSHSKKSHRQGERTRERHKSPRNKDGRGSEKSVTIQPPTGEPLLGNDSTRTEEVQDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCKRYLGLTVASFLGLLVFLTPIAFILLPPILWRDELEPCGTICEGLFISMAFKLLILLIGTWALFFRKRRADMPRVFVFRALLLVLIFLFVVSYWLFYGVRILDSRDRNYQGIVQYAVSLVDALLFIHYLAIVLLELRQLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRKARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARALQKYLRITRQQNYHSMESILQHLAFCITNGMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLVSDEAVTNGLRDGIVFVLKCLDFSLVVNVKKIPFIILSEEFIDPKSHKFVLRLQSETSV", "length": 524 }, "evidence": [ { "id": "E1BNR7", "url": "https://omabrowser.org/oma/group/E1BNR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BNR7", "url": "https://www.uniprot.org/uniprotkb/E1BNR7" } ], "pmid": "" }, { "name": "lateral plasma membrane", "id": "GO:0016328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016328", "evidence": [ { "database": "UniProtKB", "id": "E1BNR7", "url": "https://www.uniprot.org/uniprotkb/E1BNR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNR7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 564, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNR7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNR7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 360, "end_pos": 362 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NJ70-1", "uniprot_ac": "A0ABI0NJ70", "uniprot_id": "A0ABI0NJ70_BOVIN", "mass": { "chemical_mass": 48167.0, "monoisotopic_mass": 48167.0 }, "refseq": { "ac": "XP_059737215", "name": "fructose-bisphosphate aldolase A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059737215" }, "gene_names": [ { "name": "ALDOA", "type": "recommended", "evidence": [ { "id": "A0ABI0NJ70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70" } ] }, { "name": "ALDOA", "type": "synonym", "evidence": [ { "id": "XP_059737215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059737215" } ] } ], "protein_names": [ { "name": "Fructose-bisphosphate aldolase", "type": "recommended", "evidence": [ { "id": "A0ABI0NJ70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70/entry#names_and_taxonomy" } ] }, { "name": "4.1.2.13", "type": "synonym", "evidence": [ { "id": "A0ABI0NJ70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70/entry#names_and_taxonomy" } ] }, { "name": "fructose-bisphosphate aldolase A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059737215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059737215" } ] } ], "function": [ { "annotation": "Catalyzes the aldol cleavage of fructose 1,6-biphosphate to form two triosephosphates dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate in glycolysis as well as the reverse stereospecific aldol addition reaction in gluconeogenesis. In fructolysis, metabolizes fructose 1-phosphate derived from the phosphorylation of dietary fructose by fructokinase into dihydroxyacetone phosphate and D-glyceraldehyde. Acts as an adapter independently of its enzymatic activity, exerts a tumor suppressor role by stabilizing the ternary complex with G6PD and TP53 to inhibit G6PD activity and keep oxidative pentose phosphate metabolism in check.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70#function" }, { "database": "UniProtKB", "id": "ARBA00045914", "url": "https://www.uniprot.org/uniprotkb/ARBA00045914#function" }, { "database": "UniProtKB", "id": "A0A3Q1NGQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGQ6#function" }, { "database": "UniProtKB", "id": "A0A3Q1LMG1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMG1#function" }, { "database": "UniProtKB", "id": "F6R3F7", "url": "https://www.uniprot.org/uniprotkb/F6R3F7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ALDOA", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70", "locus": { "chromosome": "25", "start_pos": 26212566, "end_pos": 26217280, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012927", "url": "https://www.ensembl.org/id/ENSBTAG00000012927" } ] } } ], "crossref": [ { "id": "ENSBTAG00000012927", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012927", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00948", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00948", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "509566", "url": "https://www.ncbi.nlm.nih.gov/gene/509566", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMG1", "url": "https://www.orthodb.org/?gene=A0A3Q1LMG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11627", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11627", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00274", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00274", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059737215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059737215", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14729", "url": "https://www.rhea-db.org/rhea/14729", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "30851", "url": "https://www.rhea-db.org/rhea/30851", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LMG1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NGQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NGQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ70-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R3F7", "url": "https://www.uniprot.org/uniprotkb/F6R3F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R3F7-1", "url": "https://www.uniprot.org/uniprotkb/F6R3F7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTLGLLPSAQLLIPKYSGLVLLPGKVTPMAQRKPEGSSFHMTCLSMALAYSFRPDANIQPHPQLGNTQKQTELGKALTGTMPHQYPALTPEQKKELCDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKAKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSSLAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATVTALRRTVPPAVPGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGKAGAAASESLFISNHAY", "length": 445, "header": "tr|A0ABI0NJ70-1|A0ABI0NJ70_BOVIN Isoform 1 of Fructose-bisphosphate aldolase OS=Bos taurus OX=9913 GN=ALDOA PE=1 SV=1 CANONICAL=A0ABI0NJ70-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMG1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70/entry#A0A3Q1LMG1-1", "sequence": { "sequence": "MPHQYPALTPEQKKELCDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKAKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSSLAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATVTALRRTVPPAVPGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALVRMGRRRAGCWGGWDSEKGPSHSAPLPS", "length": 361, "header": "tr|A0A3Q1LMG1-1|A0ABI0NJ70_BOVIN Computationally mapped isoform of Fructose-bisphosphate aldolase OS=Bos taurus OX=9913 GN=ALDOA PE=1 SV=2 CANONICAL=A0ABI0NJ70-1" }, "locus": { "chromosome": "25", "start_pos": 26215646, "end_pos": 26212876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083687.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083687.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057869.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057869.2" } ] } }, { "isoform_ac": "A0A3Q1NGQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70/entry#A0A3Q1NGQ6-1", "sequence": { "sequence": "MAQRKPEGSSFHMTCLSMALAYSFRPDANIQPHPQLGNTQKQTELGKALTGTMPHQYPALTPEQKKELCDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKAKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSSLAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATVTALRRTVPPAVPGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGKAGAAASESLFISNHAY", "length": 416, "header": "tr|A0A3Q1NGQ6-1|A0ABI0NJ70_BOVIN Computationally mapped isoform of Fructose-bisphosphate aldolase OS=Bos taurus OX=9913 GN=ALDOA PE=1 SV=1 CANONICAL=A0ABI0NJ70-1" }, "locus": { "chromosome": "25", "start_pos": 26216000, "end_pos": 26212780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067155.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067155.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071019.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071019.2" } ] } }, { "isoform_ac": "A0ABI0NJ70-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70/entry#A0ABI0NJ70-1", "sequence": { "sequence": "MRTLGLLPSAQLLIPKYSGLVLLPGKVTPMAQRKPEGSSFHMTCLSMALAYSFRPDANIQPHPQLGNTQKQTELGKALTGTMPHQYPALTPEQKKELCDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKAKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSSLAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATVTALRRTVPPAVPGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGKAGAAASESLFISNHAY", "length": 445, "header": "tr|A0ABI0NJ70-1|A0ABI0NJ70_BOVIN Isoform 1 of Fructose-bisphosphate aldolase OS=Bos taurus OX=9913 GN=ALDOA PE=1 SV=1 CANONICAL=A0ABI0NJ70-1" }, "locus": { "chromosome": "25", "start_pos": 26216087, "end_pos": 26212780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152198.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152198.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104130.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104130.1" } ] } }, { "isoform_ac": "F6R3F7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70/entry#F6R3F7-1", "sequence": { "sequence": "MPHQYPALTPEQKKELCDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKAKGGVVGIKVRGHLPPPLAGSDPSIPSSGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSSLAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATVTALRRTVPPAVPGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGKAGAAASESLFISNHAY", "length": 365, "header": "tr|F6R3F7-1|A0ABI0NJ70_BOVIN Computationally mapped isoform of Fructose-bisphosphate aldolase OS=Bos taurus OX=9913 GN=ALDOA PE=1 SV=1 CANONICAL=A0ABI0NJ70-1" }, "locus": { "chromosome": "25", "start_pos": 26215646, "end_pos": 26212780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017177.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017177.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017177.5", "url": "https://www.ensembl.org/id/ENSBTAP00000017177.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 316, "start_aa": "Thr", "end_pos": 316, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr316", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "fructose-bisphosphate aldolase activity", "id": "GO:0004332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004332", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70" } ], "pmid": "" }, { "name": "fructose-1-phosphate aldolase activity", "id": "GO:0061609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061609", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14729", "name": "", "equation": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NJ70-1", "G3MXL6-1", "Q3T0S5-1", "A0AAA9S4U4-1" ], "evidence": [ { "id": "14729", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14729" } ] }, { "id": "30851", "name": "", "equation": "beta-D-fructose 1-phosphate = D-glyceraldehyde + dihydroxyacetone phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MXL6-1", "Q3T0S5-1", "A0AAA9S4U4-1", "A0ABI0NJ70-1" ], "evidence": [ { "id": "30851", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30851" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9S4U4", "gene_name": "ALDOC", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0AAA9S4U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4U4" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0AAA9S4U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4U4" } ] } ] }, { "uniprot_ac": "A0ABI0NJ70", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24889", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24889", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002689895", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689895", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LPM2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M585", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M585", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M585-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M585-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NHF0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NHF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NHF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NHF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7V0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7V0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQT0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQT0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TG31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TG31-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLY3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLY3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH0", "url": "https://www.uniprot.org/uniprotkb/E1BNH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXZ8", "url": "https://www.uniprot.org/uniprotkb/G3MXZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXZ8-1", "url": "https://www.uniprot.org/uniprotkb/G3MXZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDDGGRRNAPGALMEAGRGAGPAGMAEPAALPRVRAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPLPAAPAAPPSNLADPGLEPAGAQEPGPDPAPAPVPAPDGGPREEIAATRKEDAGAPEARPELGRARREEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSAIALRLWVEDPKKLKGKPKDSGAIEFTFDLERETPEDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRKRIWPALQPQEQRDLGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPASATSLASDSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPASQCVCSPPVSVSDGPVLPHSLPSLGAYQQPATPGLSVGSVPPPARPPLPQQPFPEPAMSFAPVLPPPSAPVPTGPGQPTAPAHQPSLLAQPVPLPQVLAPQPVGPLQPAPSHLPPYLAPASQVVAPAQLKPLQMPPAPLQPLAQIPPQMPPLPVVPPIAPLATVDSLPTALPDLPATSGPTVPPPSQYFPPAVILPSLPLSATPAPLPASPALPLQTVKLPHPAGAPLAVPCQTIVPNVAATATAIPLLAVAPQGVAALSIHPTVAQLPAQPVYPAAFPQMVPSDVPPSPLHAAQTVQAAAPQPTPPVLPQPHQPSVARLPEQAAPAASAGSQILLGHPPTYAVDVTTQVATVPAPAAILSPPLPEVLLPPVPELLPQLPGSLAPTVIAAPQSVPVQTAALLPPANLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQPSLPQSCESYGGSDVPSGREMSDSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDRASDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAVEAPESSPPLPLSSLQPDTSQDSAPSKDQLSSKEKPSFSTDLQLLSQAGPRDLPGGAPAPLVPSSPPVTALSQDMAPPAASPKLEPATGPAMQAGGPGTPQGPASEHKTPWPLMETLDAQLAAQSPGMGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLSALAPTSGAPGGASQPTVSQPLPPLPTVVGAISLATPQLPSPPLAPTAPPQPPSTLESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEAGDRDFTLEPPRGDEPRTEASGGSLGLLPQPALEKSEVAPGLEVTLEQSVSLSVTAESSLSHTLGREGAQVASDSRTAPRAPQDVPASAIPAHLEPTDRTSRVPGETLAESMQSCLGMLIEGGQDSQPQPHSTLVSGSPLKWPGQQDGSSPAKTVGRFSVVSTQDEWTLASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRAQTASSIEVGMEEPLSSDSGDESPRRRPSVQKHASLPSSSGGVASDFVKKAAAFLQRSSRAGSPCLETPSRMGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPTAASDPCGKAVQTQQPCSVRASLSADICSGLASDGGGAHGPGWTVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLVPGPEPGPQPALHIQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGATPLKPSLNQLKQTQKLHDMEATAGWPLASGEARAMNTSRTAMGMPCLAPVPSPVPTVVIPGAASALPVPMPDSESEKPD", "length": 2167, "header": "tr|E1BNH0-1|E1BNH0_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=WNK2 PE=4 SV=3 CANONICAL=E1BNH0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPM2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH0/entry#A0A3Q1LPM2-1", "sequence": { "sequence": "MDDDGGRRNAPGALMEAGRGAGPAGMAEPAALPRVRAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPLPAAPAAPPSNLADPGLEPAGAQEPGPDPAPAPVPAPDGGPREEIAATRKEDAGAPEARPELGRARREEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSAIALRLWVEDPKKLKGKPKDSGAIEFTFDLERETPEDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRKRIWPALQPQEQRDLGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPASATSLASDSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPASQCVCSPPVSVSDGPVLPHSLPSLGAYQQPATPGLSVGSVPPPARPPLPQQPFPEPAMSFAPVLPPPSAPVPTGPGQPTAPAHQPSLLAQPVPLPQVLAPQPVGPLQPAPSHLPPYLAPASQVVAPAQLKPLQMPPAPLQPLAQIPPQMPPLPVVPPIAPLATVDSLPTALPDLPATSGPTVPPPSQYFPPAVILPSLPLSATPAPLPASPALPLQTVKLPHPAGAPLAVPCQTIVPNVAATATAIPLLAVAPQGVAALSIHPTVAQLPAQPVYPAAFPQMVPSDVPPSPLHAAQTVQAAAPQPTPPVLPQPHQPSVARLPEQAAPAASAGSQILLGHPPTYAVDVTTQVATVPAPAAILSPPLPEVLLPPVPELLPQLPGSLAPTVIAAPQSVPVQTAALLPPANLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQPSLPQSCESYGGSDVPSGREMSDSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDRASDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAVEAPESSPPLPLSSLQPDTSQDSAPSKDQLSSKEKPSFSTDLQLLSQAGPRDLPGGAPAPLVPSSPPVTALSQDMAPPAASPKLEPATGPAMQAGGPGTPQGPASEHKTPWPLMETLDAQLAAQSPGMGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLSALAPTSGAPGGASQPTVSQPLPPLPTVVGAISLATPQLPSPPLAPTAPPQPPSTLESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEAGDRDFTLEPPRGDEPRTEASGGSLGLLPQPALEKSEVAPGLEVTLEQSVSLSVTAESSLSHTLGREGAQVASDSRTAPRAPQDVPASAIPAHLEPTDRTSRVPGETLAESMQSCLGMLIEGGQDSQPQPHSTLVSGSPLKWPGQQDGSSPAKTVGRFSVVSTQDEWTLASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRAQTASSIEVGMEEPLSSDSGDESPRRRPSVQKHASLPSSSGGVASDFVKKAAAFLQRSSRAGSPCLETPSRMGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPTAASDPCGKAVQTQQPCSVRASLSADICSGLASDGGGAHGPGSALKRLCLGKEHSSRSSTSSLVPGPEPGPQPALHIQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGATPLKPSLNQLKQTQKLHDMEATAGWPLASGEARAMNTSRTAMGMPCLAPVPSPVPTVVIPGAASALPVPMPDSESEKPD", "length": 2134, "header": "tr|A0A3Q1LPM2-1|E1BNH0_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=WNK2 PE=4 SV=2 CANONICAL=E1BNH0-1" }, "locus": { "chromosome": "8", "start_pos": 84699095, "end_pos": 84553138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080863.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080863.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058889.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058889.2" } ] } }, { "isoform_ac": "A0A3Q1M585-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH0/entry#A0A3Q1M585-1", "sequence": { "sequence": "MDDDGGRRNAPGALMEAGRGAGPAGMAEPAALPRVRAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPLPAAPAAPPSNLADPGLEPAGAQEPGPDPAPAPVPAPDGGPREEIAATRKEDAGAPEARPELGRARREEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSAIALRLWVEDPKKLKGKPKDSGAIEFTFDLERETPEDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRKRIWPALQPQEQRDLGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPASATSLASDSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPASQCVCSPPVSVSDGPVLPHSLPSLGAYQQPATPGLSVGSVPPPARPPLPQQPFPEPAMSFAPVLPPPSAPVPTGPGQPTAPAHQPSLLAQPVPLPQVLAPQPVGPLQPAPSHLPPYLAPASQVVAPAQLKPLQMPPAPLQPLAQIPPQMPPLPVVPPIAPLATVDSLPTALPDLPATSGPTVPPPSQYFPPAVILPSLPLSATPAPLPASPALPLQTVKLPHPAGAPLAVPCQTIVPNVAATATAIPLLAVAPQGVAALSIHPTVAQLPAQPVYPAAFPQMVPSDVPPSPLHAAQTVQAAAPQPTPPVLPQPHQPSVARLPEQAAPAASAGSQILLGHPPTYAVDVTTQVATVPAPAAILSPPLPEVLLPPVPELLPQLPGSLAPTVIAAPQSVPVQTAALLPPANLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQPSLPQSCESYGGSDVPSGREMSDSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDRASDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAVEAPESSPPLPLSSLQPDTSQDSAPSKDQLSSKEKPSFSTDLQLLSQAGPRDLPGGAPAPLVPSSPPVTALSQDMAPPAASPKLEPATGPAMQAGGPGTPQGPASEHKTPWPLMETLDAQLAAQSPGMGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLSALAPTSGAPGGASQPTVSQPLPPLPTVVGAISLATPQLPSPPLAPTAPPQPPSTLESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEAGDRDFTLEPPRGDEPRTEASGGSLGLLPQPALEKSEVAPGLEVTLEQSVSLSVTAESSLSHTLGREGAQVASDSRTAPRAPQDVPASAIPAHLEPTDRTSRVPGETLAESMQSCLGMLIEGGQDSQPQPHSTLVSGSPLKWPGQQDGSSPAKTVGRFSVVSTQDEWTLASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRAQTASSIEVGMEEPLSSDSGDESPRRRPSVQKHASLPSSSGGVASDFVKKAAAFLQRSSRAGSPCLETPSRMGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPTAASDPCGKAVQTQQPCSVRASLSADICSGLASDGGGAHGPGSSTSSLVPGPEPGPQPALHIQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGATPLKPSLNQLKQTQKLHDMEATAGWPLASGEARAMNTSRTAMGMPCLAPVPSPVPTVVIPGAASALPVPMPDSESEKPD", "length": 2119, "header": "tr|A0A3Q1M585-1|E1BNH0_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=WNK2 PE=4 SV=2 CANONICAL=E1BNH0-1" }, "locus": { "chromosome": "8", "start_pos": 84699095, "end_pos": 84553138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072956.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072956.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063446.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063446.2" } ] } }, { "isoform_ac": "A0A3Q1NHF0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH0/entry#A0A3Q1NHF0-1", "sequence": { "sequence": "MDDDGGRRNAPGALMEAGRGAGPAGMAEPAALPRVRAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPLPAAPAAPPSNLADPGLEPAGAQEPGPDPAPAPVPAPDGGPREEIAATRKEDAGAPEARPELGRARREEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSAIALRLWVEDPKKLKGKPKDSGAIEFTFDLERETPEDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRKRIWPALQPQEQRDLGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPASATSLASDSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPASQCVCSPPVSVSDGPVLPHSLPSLGAYQQPATPGLSVGSVPPPARPPLPQQPFPEPAMSFAPVLPPPSAPVPTGPGQPTAPAHQPSLLAQPVPLPQVLAPQPVGPLQPAPSHLPPYLAPASQVVAPAQLKPLQMPPAPLQPLAQIPPQMPPLPVVPPIAPLATVDSLPTALPDLPATSGPTVPPPSQYFPPAVILPSLPLSATPAPLPASPALPLQTVKLPHPAGAPLAVPCQTIVPNVAATATAIPLLAVAPQGVAALSIHPTVAQLPAQPVYPAAFPQMVPSDVPPSPLHAAQTVQAAAPQPTPPVLPQPHQPSVARLPEQAAPAASAGSQILLGHPPTYAVDVTTQVATVPAPAAILSPPLPEVLLPPVPELLPQLPGSLAPTVIAAPQSVPVQTAALLPPANLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQPSLPQSCESYGGSDVPSGREMSDSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDRASDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAVEAPESSPPLPLSSLQPDTSQDSAPSKDQLSSKEKPSFSTDLQLLSQAGPRDLPGGAPAPLVPSSPPVTALSQDMAPPAASPKLEPATGPAMQAGGPGTPQGPASEHKTPWPLMETLDAQLAAQSPGMGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLSALAPTSGAPGGASQPTVSQPLPPLPTVVGAISLATPQLPSPPLAPTAPPQPPSTLESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEAGDRDFTLEPPRGDEPRTEASGGSLGLLPQPALEKSEVAPGLEVTLEQSVSLSVTAESSLSHTLGREGAQVASDSRTAPRAPQDVPASAIPAHLEPTDRTSRVPGETLAESMQSCLGMLIEGGQDSQPQPHSTLVSGSPLKWPGQQDGSSPAKTVGRFSVVSTQDEWTLASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRAQTASSIEVGMEEPLSSDSGDESPRRRPSVQKHASLPSSSGGVASDFVKKAAAFLQRSSRAGSPCLETPSRMGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVVASSTGSSTSSLVPGPEPGPQPALHIQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGATPLKPSLNQLKQTQKLHDMEATAGWPLASGEARAMNTSRTAMGMPCLAPVPSPVPTVVIPGAASALPVPMPDSESEKPD", "length": 2056, "header": "tr|A0A3Q1NHF0-1|E1BNH0_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=WNK2 PE=4 SV=2 CANONICAL=E1BNH0-1" }, "locus": { "chromosome": "8", "start_pos": 84699095, "end_pos": 84553138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074951.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074951.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071387.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071387.2" } ] } }, { "isoform_ac": "A0AAA9S7V0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH0/entry#A0AAA9S7V0-1", "sequence": { "sequence": "MDDDGGRRNAPGALMEAGRGAGPAGMAEPAALPRVRAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPLPAAPAAPPSNLADPGLEPAGAQEPGPDPAPAPVPAPDGGPREEIAATRKEDAGAPEARPELGRARREEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSAIALRLWVEDPKKLKGKPKDSGAIEFTFDLERETPEDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRKRIWPALQPQEQRDLGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPASATSLASDSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPASQCVCSPPVSVSDGPVLPHSLPSLGAYQQPATPGLSVGSVPPPARPPLPQQPFPEPAMSFAPVLPPPSAPVPTGPGQPTAPAHQPSLLAQPVPLPQVLAPQPVGPLQPAPSHLPPYLAPASQVVAPAQLKPLQMPPAPLQPLAQIPPQMPPLPVVPPIAPLATVDSLPTALPDLPATSGPTVPPPSQYFPPAVILPSLPLSATPAPLPASPALPLQTVKLPHPAGAPLAVPCQTIVPNVAATATAIPLLAVAPQGVAALSIHPTVAQLPAQPVYPAAFPQMVPSDVPPSPLHAAQTVQAAAPQPTPPVLPQPHQPSVARLPEQAAPAASAGSQILLGHPPTYAVDVTTQVATVPAPAAILSPPLPEVLLPPVPELLPQLPGSLAPTVIAAPQSVPVQTAALLPPANLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQPSLPQSCESYGGSDVPSGREMSDSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDRASDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAVEAPESSPPLPLSSLQPDTSQDSAPSKDQLSSKEKPSFSTDLQLLSQAGPRDLPGGAPAPLVPSSPPVTALSQDMAPPAASPKLEPATGPAMQAGGPGTPQGPASEHKTPWPLMETLDAQLAAQSPGMGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLSALAPTSGAPGGASQPTVSQPLPPLPTVVGAISLATPQLPSPPLAPTAPPQPPSTLESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEAGDRDFTLEPPRGDEPRTEASGGSLGLLPQPALEKSEVAPGLEVTLEQSVSLSVTAESSLSHTLGREGAQVASDSRTAPRAPQDVPASAIPAHLEPTDRTSRVPGETLAESMQSCLGMLIEGGQDSQPQPHSTLVSGSPLKWPGQQDGSSPAKTVGRFSVVSTQDEWTLASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRAQTASSIEVGMEEPLSSDSGDESPRRRPSVQKHASLPSSSGGVASDFVKKAAAFLQRSSRAGSPCLETPSRMGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPTAASDPCGKAVQTQQPCSVRASLSADICSGLASDGGGAHGPGWTVYHPTSERVTYKSSSKPRARFLSGPVSVSICLYLFFCILSPPGPWFLPCPSLSSLSSIHFVGHLTPPPLKSCT", "length": 2063, "header": "tr|A0AAA9S7V0-1|E1BNH0_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=WNK2 PE=4 SV=1 CANONICAL=E1BNH0-1" }, "locus": { "chromosome": "8", "start_pos": 84667163, "end_pos": 84553138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109913.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109913.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080013.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080013.1" } ] } }, { "isoform_ac": "A0AAA9SQT0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH0/entry#A0AAA9SQT0-1", "sequence": { "sequence": "MDDDGGRRNAPGALMEAGRGAGPAGMAEPAALPRVRAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPLPAAPAAPPSNLADPGLEPAGAQEPGPDPAPAPVPAPDGGPREEIAATRKEDAGAPEARPELGRARREEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSAIALRLWVEDPKKLKGKPKDSGAIEFTFDLERETPEDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRKRIWPALQPQEQRDLGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPASATSLASDSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPASQCVCSPPVSVSDGPVLPHSLPSLGAYQQPATPGLSVGSVPPPARPPLPQQPFPEPAMSFAPVLPPPSAPVPTGPGQPTAPAHQPSLLAQPVPLPQVLAPQPVGPLQPAPSHLPPYLAPASQVVAPAQLKPLQMPPAPLQPLAQIPPQMPPLPVVPPIAPLATVDSLPTALPDLPATSGPTVPPPSQYFPPAVILPSLPLSATPAPLPASPALPLQTVKLPHPAGAPLAVPCQTIVPNVAATATAIPLLAVAPQGVAALSIHPTVAQLPAQPVYPAAFPQMVPSDVPPSPLHAAQTVQAAAPQPTPPVLPQPHQPSVARLPEQAAPAASAGSQILLGHPPTYAVDVTTQVATVPAPAAILSPPLPEVLLPPVPELLPQLPGSLAPTVIAAPQSVPVQTAALLPPANLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQPSLPQSCESYGGSDVPSGREMSDSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDRASDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAVEAPESSPPLPLSSLQPDTSQDSAPSKDQLSSKEKPSFSTDLQLLSQAGPRDLPGGAPAPLVPSSPPVTALSQDMAPPAASPKLEPATGPAMQAGGPGTPQGPASEHKTPWPLMETLDAQLAAQSPGMGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLSALAPTSGAPGGASQPTVSQPLPPLPTVVGAISLATPQLPSPPLAPTAPPQPPSTLESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEAGDRDFTLEPPRGDEPRTEASGGSLGLLPQPALEKSEVAPGLEVTLEQSVSLSVTAESSLSHTLGREGAQVASDSRTAPRAPQDVPASAIPAHLEPTDRTSRVPGETLAESMQSCLGMLIEGGQDSQPQPHSTLVSGSPLKWPGQQDGSSPAKTVGRFSVVSTQDEWTLASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRAQTASSIEVGMEEPLSSDSGDESPRRRPSVQKHASLPSSSGGVASDFVKKAAAFLQRSSRAGSPCLETPSRMGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVVASSTGSALKRLCLGKEHSSRNYRVFYPLSASIAWALLWLVRIRVSTAGPGAEGPAGRRVWTRSVPTLRGCCWASTWRDSCPWHTFKPPWLLEFVHSHQFTSNWLSFSETSMNYQSLIGSFSKTVGMSISFKC", "length": 2052, "header": "tr|A0AAA9SQT0-1|E1BNH0_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=WNK2 PE=4 SV=1 CANONICAL=E1BNH0-1" }, "locus": { "chromosome": "8", "start_pos": 84674166, "end_pos": 84553138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110388.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110388.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087708.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087708.1" } ] } }, { "isoform_ac": "A0AAA9TG31-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH0/entry#A0AAA9TG31-1", "sequence": { "sequence": "MDDDGGRRNAPGALMEAGRGAGPAGMAEPAALPRVRAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPLPAAPAAPPSNLADPGLEPAGAQEPGPDPAPAPVPAPDGGPREEIAATRKEDAGAPEARPELGRARREEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSAIALRLWVEDPKKLKGKPKDSGAIEFTFDLERETPEDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRKRIWPALQPQEQRDLGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPASATSLASDSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPASQCVCSPPVSVSDGPVLPHSLPSLGAYQQPATPGLSVGSVPPPARPPLPQQPFPEPAMSFAPVLPPPSAPVPTGPGQPTAPAHQPSLLAQPVPLPQVLAPQPVGPLQPAPSHLPPYLAPASQVVAPAQLKPLQMPPAPLQPLAQIPPQMPPLPVVPPIAPLATVDSLPTALPDLPATSGPTVPPPSQYFPPAVILPSLPLSATPAPLPASPALPLQTVKLPHPAGAPLAVPCQTIVPNVAATATAIPLLAVAPQGVAALSIHPTVAQLPAQPVYPAAFPQMVPSDVPPSPLHAAQTVQAAAPQPTPPVLPQPHQPSVARLPEQAAPAASAGSQILLGHPPTYAVDVTTQVATVPAPAAILSPPLPEVLLPPVPELLPQLPGSLAPTVIAAPQSVPVQTAALLPPANLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQPSLPQSCESYGGSDVPSGREMSDSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPRLTILNVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDRASDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAVEAPESSPPLPLSSLQPDTSQDSAPSKDQLSSKEKPSFSTDLQLLSQAGPRDLPGGAPAPLVPSSPPVTALSQDMAPPAASPKLEPATGPAMQAGGPGTPQGPASEHKTPWPLMETLDAQLAAQSPGMGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLSALAPTSGAPGGASQPTVSQPLPPLPTVVGAISLATPQLPSPPLAPTAPPQPPSTLESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEAGDRDFTLEPPRGDEPRTEASGGSLGLLPQPALEKSEVAPGLEVTLEQSVSLSVTAESSLSHTLGREGAQVASDSRTAPRAPQDVPASAIPAHLEPTDRTSRVPGETLAESMQSCLGMLIEGGQDSQPQPHSTLVSGSPLKWPGQQDGSSPAKTVGRFSVVSTQDEWTLASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRAQTASSIEVGMEEPLSSDSGDESPRRRPSVQKHASLPSSSGGVASDFVKKAAAFLQRSSRAGSPCLETPSRMGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPTAASDPCGKAVQTQQPCSVRASLSADICSGLASDGGGAHGPGSSTSSLVPGPEPGPQPALHIQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGATPLKPSLNQLKQTQKLHDMEATAGWPLASGEARAMNTSRTAMGMPCLAPVPSPVPTVVIPGAASALPVPMPDSESEKPD", "length": 2080, "header": "tr|A0AAA9TG31-1|E1BNH0_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=WNK2 PE=4 SV=1 CANONICAL=E1BNH0-1" }, "locus": { "chromosome": "8", "start_pos": 84699095, "end_pos": 84553138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087702.1", "url": "https://www.ensembl.org/id/ENSBTAT00000087702.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095988.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095988.1" } ] } }, { "isoform_ac": "A0AAA9TLY3-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH0/entry#A0AAA9TLY3-1", "sequence": { "sequence": "MDDDGGRRNAPGALMEAGRGAGPAGMAEPAALPRVRAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPLPAAPAAPPSNLADPGLEPAGAQEPGPDPAPAPVPAPDGGPREEIAATRKEDAGAPEARPELGRARREEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSAIALRLWVEDPKKLKGKPKDSGAIEFTFDLERETPEDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRKRIWPALQPQEQRDLGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPASATSLASDSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPASQCVCSPPVSVSDGPVLPHSLPSLGAYQQPATPGLSVGSVPPPARPPLPQQPFPEPAMSFAPVLPPPSAPVPTGPGQPTAPAHQPSLLAQPVPLPQVLAPQPVGPLQPAPSHLPPYLAPASQVVAPAQLKPLQMPPAPLQPLAQIPPQMPPLPVVPPIAPLATVDSLPTALPDLPATSGPTVPPPSQYFPPAVILPSLPLSATPAPLPASPALPLQTVKLPHPAGAPLAVPCQTIVPNVAATATAIPLLAVAPQGVAALSIHPTVAQLPAQPVYPAAFPQMVPSDVPPSPLHAAQTVQAAAPQPTPPVLPQPHQPSVARLPEQAAPAASAGSQILLGHPPTYAVDVTTQVATVPAPAAILSPPLPEVLLPPVPELLPQLPGSLAPTVIAAPQSVPVQTAALLPPANLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQPSLPQSCESYGGSDVPSGREMSDSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDRASDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAVEAPESSPPLPLSSLQPDTSQDSAPSKDQLSSKEKPSFSTDLQLLSQAGPRDLPGGAPAPLVPSSPPVTALSQDMAPPAASPKLEPATGPAMQAGGPGTPQGPASEHKTPWPLMETLDAQLAAQSPGMGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLSALAPTSGAPGGASQPTVSQPLPPLPTVVGAISLATPQLPSPPLAPTAPPQPPSTLESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEAGDRDFTLEPPRGDEPRTEASGGSLGLLPQPALEKSEVAPGLEVTLEQSVSLSVTAESSLSHTLGREGAQVASDSRTAPRAPQDVPASAIPAHLEPTDRTSRVPGETLAESMQSCLGMLIEGGQDSQPQPHSTLVSGSPLKWPGQQDGSSPAKTVGRFSVVSTQDEWTLASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRAQTASSIEVGMEEPLSSDSGDESPRRRPSVQKHASLPSSSGGVASDFVKKAAAFLQRSSRAGSPCLETPSRMGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPTAASDPCGKAVQTQQPCSVRASLSADICSGLASDGGGAHGPDEHISNGNGDAMSGPGTQPCTHRGHSWSCLSPSCAHARF", "length": 2026, "header": "tr|A0AAA9TLY3-1|E1BNH0_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=WNK2 PE=4 SV=1 CANONICAL=E1BNH0-1" }, "locus": { "chromosome": "8", "start_pos": 84699076, "end_pos": 84553138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117320.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117320.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099430.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099430.1" } ] } }, { "isoform_ac": "E1BNH0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH0/entry#E1BNH0-1", "sequence": { "sequence": "MDDDGGRRNAPGALMEAGRGAGPAGMAEPAALPRVRAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPLPAAPAAPPSNLADPGLEPAGAQEPGPDPAPAPVPAPDGGPREEIAATRKEDAGAPEARPELGRARREEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSAIALRLWVEDPKKLKGKPKDSGAIEFTFDLERETPEDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRKRIWPALQPQEQRDLGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPASATSLASDSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPASQCVCSPPVSVSDGPVLPHSLPSLGAYQQPATPGLSVGSVPPPARPPLPQQPFPEPAMSFAPVLPPPSAPVPTGPGQPTAPAHQPSLLAQPVPLPQVLAPQPVGPLQPAPSHLPPYLAPASQVVAPAQLKPLQMPPAPLQPLAQIPPQMPPLPVVPPIAPLATVDSLPTALPDLPATSGPTVPPPSQYFPPAVILPSLPLSATPAPLPASPALPLQTVKLPHPAGAPLAVPCQTIVPNVAATATAIPLLAVAPQGVAALSIHPTVAQLPAQPVYPAAFPQMVPSDVPPSPLHAAQTVQAAAPQPTPPVLPQPHQPSVARLPEQAAPAASAGSQILLGHPPTYAVDVTTQVATVPAPAAILSPPLPEVLLPPVPELLPQLPGSLAPTVIAAPQSVPVQTAALLPPANLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQPSLPQSCESYGGSDVPSGREMSDSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDRASDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAVEAPESSPPLPLSSLQPDTSQDSAPSKDQLSSKEKPSFSTDLQLLSQAGPRDLPGGAPAPLVPSSPPVTALSQDMAPPAASPKLEPATGPAMQAGGPGTPQGPASEHKTPWPLMETLDAQLAAQSPGMGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLSALAPTSGAPGGASQPTVSQPLPPLPTVVGAISLATPQLPSPPLAPTAPPQPPSTLESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEAGDRDFTLEPPRGDEPRTEASGGSLGLLPQPALEKSEVAPGLEVTLEQSVSLSVTAESSLSHTLGREGAQVASDSRTAPRAPQDVPASAIPAHLEPTDRTSRVPGETLAESMQSCLGMLIEGGQDSQPQPHSTLVSGSPLKWPGQQDGSSPAKTVGRFSVVSTQDEWTLASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRAQTASSIEVGMEEPLSSDSGDESPRRRPSVQKHASLPSSSGGVASDFVKKAAAFLQRSSRAGSPCLETPSRMGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPTAASDPCGKAVQTQQPCSVRASLSADICSGLASDGGGAHGPGWTVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLVPGPEPGPQPALHIQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGATPLKPSLNQLKQTQKLHDMEATAGWPLASGEARAMNTSRTAMGMPCLAPVPSPVPTVVIPGAASALPVPMPDSESEKPD", "length": 2167, "header": "tr|E1BNH0-1|E1BNH0_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=WNK2 PE=4 SV=3 CANONICAL=E1BNH0-1" }, "locus": { "chromosome": "8", "start_pos": 84699095, "end_pos": 84553138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000060961.4", "url": "https://www.ensembl.org/id/ENSBTAT00000060961.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053530.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053530.3" } ] } }, { "isoform_ac": "G3MXZ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH0/entry#G3MXZ8-1", "sequence": { "sequence": "MDDDGGRRNAPGALMEAGRGAGPAGMAEPAALPRVRAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPLPAAPAAPPSNLADPGLEPAGAQEPGPDPAPAPVPAPDGGPREEIAATRKEDAGAPEARPELGRARREEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSAIALRLWVEDPKKLKGKPKDSGAIEFTFDLERETPEDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRKRIWPALQPQEQRDLGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPASATSLASDSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPASQCVCSPPVSVSDGPVLPHSLPSLGAYQQPATPGLSVGSVPPPARPPLPQQPFPEPAMSFAPVLPPPSAPVPTGPGQPTAPAHQPSLLAQPVPLPQVLAPQPVGPLQPAPSHLPPYLAPASQVVAPAQLKPLQMPPAPLQPLAQIPPQMPPLPVVPPIAPLATVDSLPTALPDLPATSGPTVPPPSQYFPPAVILPSLPLSATPAPLPASPALPLQTVKLPHPAGAPLAVPCQTIVPNVAATATAIPLLAVAPQGVAALSIHPTVAQLPAQPVYPAAFPQMVPSDVPPSPLHAAQTVQAAAPQPTPPVLPQPHQPSVARLPEQAAPAASAGSQILLGHPPTYAVDVTTQVATVPAPAAILSPPLPEVLLPPVPELLPQLPGSLAPTVIAAPQSVPVQTAALLPPANLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQPSLPQSCESYGGSDVPSGREMSDSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDRASDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAVEAPESSPPLPLSSLQPDTSQDSAPSKDQLSSKEKPSFSTDLQLLSQAGPRDLPGGAPAPLVPSSPPVTALSQDMAPPAASPKLEPATGPAMQAGGPGTPQGPASEHKTPWPLMETLDAQLAAQSPGMGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLSALAPTSGAPGGASQPTVSQPLPPLPTVVGAISLATPQLPSPPLAPTAPPQPPSTLESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEAGDRDFTLEPPRGDEPRTEASGGSLGLLPQPALEKSEVAPGLEVTLEQSVSLSVTAESSLSHTLGREGAQVASDSRTAPRAPQDVPASAIPAHLEPTDRTSRVPGETLAESMQSCLGMLIEGGQDSQPQPHSTLVSGSPLKWPGQQDGSSPAKTVGRFSVVSTQDEWTLASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRAQTASSIEVGMEEPLSSDSGDESPRRRPSVQKHASLPSSSGGVASDFVKKAAAFLQRSSRAGSPCLETPSRMGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPTAASDPCGKAVQTQQPCSVRASLSADICSGLASDGGGAHGPGWTVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSSTSSLVPGPEPGPQPALHIQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGATPLKPSLNQLKQTQKLHDMEATAGWPLASGEARAMNTSRTAMGMPCLAPVPSPVPTVVIPGAASALPVPMPDSESEKPD", "length": 2152, "header": "tr|G3MXZ8-1|E1BNH0_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=WNK2 PE=4 SV=3 CANONICAL=E1BNH0-1" }, "locus": { "chromosome": "8", "start_pos": 84699095, "end_pos": 84553138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065526.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065526.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054423.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054423.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1062, "start_aa": "Thr", "end_pos": 1062, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1062", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1947, "start_aa": "Thr", "end_pos": 1947, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1947", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 673, "start_aa": "Thr", "end_pos": 673, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr673", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 822, "start_aa": "Thr", "end_pos": 822, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr822", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 844, "start_aa": "Thr", "end_pos": 844, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr844", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 946, "start_aa": "Thr", "end_pos": 946, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr946", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:506520", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506520", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E1BNH0", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BNH0", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ], "pmid": "" }, { "name": "potassium channel inhibitor activity", "id": "GO:0019870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019870", "evidence": [ { "database": "UniProtKB", "id": "E1BNH0", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BNH0", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BNH0", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ], "pmid": "" }, { "name": "positive regulation of potassium ion import across plasma membrane", "id": "GO:1903288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903288", "evidence": [ { "database": "UniProtKB", "id": "E1BNH0", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ], "pmid": "" }, { "name": "monoatomic ion homeostasis", "id": "GO:0050801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050801", "evidence": [ { "database": "UniProtKB", "id": "E1BNH0", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ], "pmid": "" }, { "name": "negative regulation of sodium ion transport", "id": "GO:0010766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010766", "evidence": [ { "database": "UniProtKB", "id": "E1BNH0", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1834, "end_pos": 1836, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2061, "end_pos": 2063, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2124, "end_pos": 2126, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", 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"uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q58D94", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] } ] }, { "uniprot_ac": "Q8MIT6", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] } ] }, { "uniprot_ac": "Q95KV0", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] } ] }, { "uniprot_ac": "Q9N0P9", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] } ] }, { "uniprot_ac": "V6F977", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 192, "end_pos": 450, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 673, 822, 844, 946, 1062, 1947 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1834, "end_pos": 1836 }, { "start_pos": 2061, "end_pos": 2063 }, { "start_pos": 2124, "end_pos": 2126 } ] }, "class_list": [], "section_stats": [ { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 6 }, { "field": "exact_o_linked_sites", "count": 6 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM50-1", "uniprot_ac": "E1BM50", "uniprot_id": "E1BM50_BOVIN", "mass": { "chemical_mass": 88452.0, "monoisotopic_mass": 88452.0 }, "refseq": {}, "gene_names": [ { "name": "KIFC2", "type": "recommended", "evidence": [ { "id": "E1BM50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM50" } ] } ], "protein_names": [ { "name": "Kinesin-like protein", "type": "recommended", "evidence": [ { "id": "E1BM50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM50/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in microtubule-dependent retrograde axonal transport. May function as the motor for the transport of multivesicular body (MVB)-like organelles in dendrites.", "evidence": [ { "database": "UniProtKB", "id": "E1BM50", "url": "https://www.uniprot.org/uniprotkb/E1BM50#function" }, { "database": "UniProtKB", "id": "ARBA00057541", "url": "https://www.uniprot.org/uniprotkb/ARBA00057541#function" }, { "database": "UniProtKB", "id": "A0A3Q1NKT4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKT4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM50", "url": "https://www.uniprot.org/uniprotkb/E1BM50" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KIFC2", "url": "https://www.uniprot.org/uniprotkb/E1BM50", "locus": { "chromosome": "14", "start_pos": 470794, "end_pos": 481078, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007753", "url": "https://www.ensembl.org/id/ENSBTAG00000007753" } ] } } ], "crossref": [ { "id": "E1BM50", "url": "https://alphafold.ebi.ac.uk/entry/E1BM50", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007753", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007753", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EWAKWSW", "url": "https://omabrowser.org/oma/group/EWAKWSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR47972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47972:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47972:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1NKT4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NKT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM50", "url": "https://www.uniprot.org/uniprotkb/E1BM50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM50-1", "url": "https://www.uniprot.org/uniprotkb/E1BM50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEEGAGLRRGGGRRSMRAGSAAGGRGVGAGTRGGVKPGPLPPRAPMYAFYSLLIYIFYSLFRRDGGAAAAADAENPAQSARCKPGSRRRAYQPSAELWTELTGLVGSSEAEDGSGGGAERCPAEVSLEEALVRLAEFLSVQLGAEESFGTPSDLSKPGDVPPLLTVTGQLLALLAWIRSPRGRQALSQGTQPVSGVQHPPPAGSPLQEESPSLSPRGEAQGQQPPQLEEDQRAWQRLEQLILGQLEELKQQLEHQEEELGQLRLGVGATDSEKRVQHLTLENKALKQSLSLTRDLLLHWGPAPHTRAPQEEAEALLELRRRLQEAQDTTEALRVQLGVQEVQLQGLQGALRQLQQETEQNCRRELQQMRGQLAGLHARMASLRQGCGDLRGLVSTFTQSCQGSLSEAQGQVSWALGALSADGAGSQLAEARQGPLPGCSGRLLELKGNIRVLCRLRPGTPSSLVSLEPGPGGTVTTCYRGHQRRFRLDWVFPPHASQEEVFRELESAVLSCLGGYSVCIFTYGQTGTGKTYSMEGPPEDPGIAPRALQSLFQEMGTGGQHRVTLSMVEIYNEAVRDLLAPGPPQRLAVRQGPAGQGGIQVAGLTHWDVPNLESLHQMLSLGRSNRATAATAMNQRSSRSHALVTLTLRTASPSRGPGTAGTLHLVDLAGSERAWKAGTAGTSQEDRDGAQRLREARTINRSLLALGGVMAALRARRPHVPFRDSQLTRLLQPALGPGATVVLLLQISTRPEDLGETVCSLKFAERVGRVELGPARPRRAPRSGTPSSLSTDTPLSGTPCTPTPSPGSPPSPGLDSGSSSALAPPEDLPS", "length": 830, "header": "tr|E1BM50-1|E1BM50_BOVIN Isoform 1 of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIFC2 PE=3 SV=3 CANONICAL=E1BM50-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NKT4-1", "url": "https://www.uniprot.org/uniprotkb/E1BM50/entry#A0A3Q1NKT4-1", "sequence": { "sequence": "MRLFRRDGGAAAAADAENPAQSARCKPGSRRRAYQPSAELWTELTGLVGSSEAEDGSGGGAERCPAEVSLEEALVRLAEFLSVQLGAEESFGTPSDLSKPGDVPPLLTVTGQLLALLAWIRSPRGRQALSQGTQPVSGVQHPPPAGSPLQEESPSLSPRGEAQGQQPPQLEEDQRAWQRLEQLILGQLEELKQQLEHQEEELGQLRLGVGATDSEKRVQHLTLENKALKQSLSLTRDLLLHWGPAPHTRAPQEEAEALLELRRRLQEAQDTTEALRVQETEQNCRRELQQMRGQLAGLHARMASLRQGCGDLRGLVSTFTQSCQGSLSEAQGQVSWALGALSADGAGSQLAEARQGPLPGCSGRLLELKGNIRVLCRLRPGTPSSLVSLEPGPGGTVTTCYRGHQRRFRLDWVFPPHASQEEVFRELESAVLSCLGGYSVCIFTYGQTGTGKTYSMEGPPEDPGIAPRALQSLFQEMGTGGQHRVTLSMVEIYNEAVRDLLAPGPPQRLAVRQGPAGQGGIQVAGLTHWDVPNLESLHQMLSLGRSNRATAATAMNQRSSRSHALVTLTLRTASPSRGPGTAGTLHLVDLAGSERAWKAGTAGTSQEDRDGAQRLREARTINRSLLALGGVMAALRARRPHVPFRDSQLTRLLQPALGPGATVVLLLQISTRPEDLGETVCSLKFAERVGRVELGPARPRRAPRSGTPSSLSTDTPLSGTPCTPTPSPGSPPSPGLDSGSSSALAPPEDLPS", "length": 752, "header": "tr|A0A3Q1NKT4-1|E1BM50_BOVIN Computationally mapped isoform of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIFC2 PE=3 SV=2 CANONICAL=E1BM50-1" }, "locus": { "chromosome": "14", "start_pos": 479098, "end_pos": 471480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075175.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075175.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072984.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072984.2" } ] } }, { "isoform_ac": "E1BM50-1", "url": "https://www.uniprot.org/uniprotkb/E1BM50/entry#E1BM50-1", "sequence": { "sequence": "MLEEGAGLRRGGGRRSMRAGSAAGGRGVGAGTRGGVKPGPLPPRAPMYAFYSLLIYIFYSLFRRDGGAAAAADAENPAQSARCKPGSRRRAYQPSAELWTELTGLVGSSEAEDGSGGGAERCPAEVSLEEALVRLAEFLSVQLGAEESFGTPSDLSKPGDVPPLLTVTGQLLALLAWIRSPRGRQALSQGTQPVSGVQHPPPAGSPLQEESPSLSPRGEAQGQQPPQLEEDQRAWQRLEQLILGQLEELKQQLEHQEEELGQLRLGVGATDSEKRVQHLTLENKALKQSLSLTRDLLLHWGPAPHTRAPQEEAEALLELRRRLQEAQDTTEALRVQLGVQEVQLQGLQGALRQLQQETEQNCRRELQQMRGQLAGLHARMASLRQGCGDLRGLVSTFTQSCQGSLSEAQGQVSWALGALSADGAGSQLAEARQGPLPGCSGRLLELKGNIRVLCRLRPGTPSSLVSLEPGPGGTVTTCYRGHQRRFRLDWVFPPHASQEEVFRELESAVLSCLGGYSVCIFTYGQTGTGKTYSMEGPPEDPGIAPRALQSLFQEMGTGGQHRVTLSMVEIYNEAVRDLLAPGPPQRLAVRQGPAGQGGIQVAGLTHWDVPNLESLHQMLSLGRSNRATAATAMNQRSSRSHALVTLTLRTASPSRGPGTAGTLHLVDLAGSERAWKAGTAGTSQEDRDGAQRLREARTINRSLLALGGVMAALRARRPHVPFRDSQLTRLLQPALGPGATVVLLLQISTRPEDLGETVCSLKFAERVGRVELGPARPRRAPRSGTPSSLSTDTPLSGTPCTPTPSPGSPPSPGLDSGSSSALAPPEDLPS", "length": 830, "header": "tr|E1BM50-1|E1BM50_BOVIN Isoform 1 of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIFC2 PE=3 SV=3 CANONICAL=E1BM50-1" }, "locus": { "chromosome": "14", "start_pos": 478376, "end_pos": 471480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010194.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010194.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010194.6", "url": "https://www.ensembl.org/id/ENSBTAP00000010194.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 785, "start_aa": "Thr", "end_pos": 785, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr785", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 803, "start_aa": "Thr", "end_pos": 803, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr803", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K857-1", "protein_name": "Kinesin-like protein", "gene_name": "Kifc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEGEIWAGLGPAPGRGGVWATGGGEVVHLLFRRDGGAAAVSDPGDPTQKSGGQPRGRRRPDQFTSELWTELNSLAGCSESEDGQKGAEGGAAEVSLEEALMRLAEFLSVQLGAEESCGTTPDLGKPGEVPPLLTVTSQLLALLAWTRSPRGRQALLQGTQPTCPVQPSTLDGSLSQEESSQSTPILDEVPRDETQEHQPPQLEEEQRVWQRLEQLILGQLEELRQQLEQQEEELSRLRLGVGVTDSEKRVQHLTLENEALKQSLSLTRDLLLHWVPGPLTRPPQEEAGALLELQGQLQEAQDTTEALRVQLGVQELQLQGLRGALQQLQQETEQNCRQELQQVHGQLAGLRARMASLRQGCGDLRGLVSTFTQSCQGSLSEAQGQVSWALGALSAGKAKTQLPEGHQAPPTGCSGRLLELKGNIRVLCRLRPAEGKPSSLVSVEPGQGGSITTCYRGRQHRFRLDWVFPQDASQEEVFRQLEPAVLSCLQGYSVCVFTYGQTGTGKTYSMEGPPEDPGIAPRALQLLFREMGTGGHHHVTLSMVEIYNEAVRDLLATGPPERLVVRQGPAGQGGIQVAGLTHWDVPNLETLHQMLSLGRSNRATAATVMNQHSSRSHALITLTLRAASPPRAQGITGTLHLVDLAGSERVWKAGVASPVQRDPNGARRLREAQAINRSLLALGGVMAALRARRPHVPFRDSQLTRLLQPALGEGTTAVLLLQISTRAEDLGETICSLKFAQRVGQVELGPARRRRTPRSGTPSSLSTDTPLTGTSCTPTPSPGSPPSPSPNSCSGLTLEPPGDLPP", "length": 807 }, "evidence": [ { "id": "E1BM50", "url": "https://omabrowser.org/oma/group/E1BM50/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2M5R2-1", "protein_name": "Kinesin-like protein", "gene_name": "Kifc2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYAFYSLLIYIFYSLFRRDGGAAAAADPGDSTQRSGGKPRGRRHPDQFTSELWTELNSLAGCSESEDGQKGAKGGAPEVSLEEALMRLAEFLSLQLGAEESCGTPSDPGKPGEVPPLLTVTSQLLALLAWTRSPRGRQVLLQGTQPACPVQPSNLDGSLSQEESSSQPTPILDEVPGDETQEHQPPQLEEEQRAWQRLEQLILGQLEELRQQLEQQEEELSRLRLGVGVTDSEKRVQHLTLENEVLKQSLSLAQDLLLRWGPGPLARAQQEEAGALLELQDQLQEAQDTTEALRAQLGVQEMQLQGLRGALQQLQQETEQNCRQELQQVHGQLAGLRARMASLRQGCGDLRGLVSTFTQSCQGSLSEAQGQVSWALGALSAGGARTQLSEGQQGPPTGCAGRLLELKGNIRVLCRVRPAEGIPSSLVSMEPGQGGTITTCYRGRQHRFRLDWVFPPDASQEEVFRQLEPAVLSCLQGYSVCIFTYGQTGTGKTYSMEGPPEDPGIAPRALQLLFREMGTGGHHHVTLSMVEIYNEAVRDLLATGPPERLVVRQGPAGQGGIQVTGLTHWDVPNLETLHQMLSLGRSNRATAATVMNQHSSRSHALVTLTLRAASPSCAQGITGTLHLVDLAGSERVWKAGVASTLQRDPNGARRLREAQSINRSLLALGGVMAALRARRPHVPFRDSQLTRLLQPALGAGTTAVLLLQISTRTEDLGETICSLKFAQRVGQVELGPARRRRAPRSGTPSSLSTDTPLTGTSCTPTPSPGSPPSPGPNSCSGLTLEPPGDLPP", "length": 792 }, "evidence": [ { "id": "E1BM50", "url": "https://omabrowser.org/oma/group/E1BM50/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08672-1", "protein_name": "Kinesin-like protein KIFC2", "gene_name": "Kifc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYAFYSLLIYIFYSLFRRDGGAAAVSDPGDPTQKSGGQPRGRRRPDQFTSELWSELNSLAGCSESEDGQKGAEGGAAEVSLEEALMRLAEFLSVQLGAEESCGTTPDLGKPGEVPPLLTVTSQLLALLAWTRSPRGRQALLQGTQPTCPVQPSTLDGSLSQEESSSQPTPILDEVPRDETQEHQPLQLEEEQRVWQRLEQLILGQLEELRQQLEQQEEELSRLRLGVGVTDSEKRVQHLTLENEALKQSLSLTRDLLLHWGPGPLPRLSQEEAGALLELQGQLQEAQDTTEALRVQLGAQELQLQGLRGALRQLQQETEQNCRQELQQVHGQLAGLRARMASLRQGCGDLRGLVSTFTQSCQGSLSEAQGQVSWALGALSAGKAKTQLSEGNQAPPTGCSGRLLELKGNIRVLCRLRPAEGQPSSLVSVEPGQGGTITTCYRGRQHCFRLDWVFPQDASQEEVFRQLEPAVLSCLQGYSVCIFTYGQTGTGKTYSMEGPPEDPGIAPRALQLLFREMGTGGHHHVTLSMVEIYNEAVRDLLATGPPERLVVRQGPAGQGGIQVAGLTHWDVPNLETLHQMLSLGRSNRATAATVMNQHSSRSHALVTLTLRAASPPRPQGITGTLHLVDLAGSERVWKAGVASPVQRDPNGARRLREAQAINRSLLALGGVMAALRARRPHVPFRDSQLTRLLQPALWAGTTAVLLLQISTRAEDLGETICSLKFAERVGQVELGPARRRRAPRSGTPSSLSTDTPLTGTSCTPTPSPGSPPSTSPNSCSGLTLEPPGDPPP", "length": 792 }, "evidence": [ { "id": "E1BM50", "url": "https://omabrowser.org/oma/group/E1BM50/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AC6-1", "protein_name": "Kinesin-like protein KIFC2", "gene_name": "KIFC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYAFYSLLIYIFYSLFRRDGGAAAAAEPGDPAQRARKPRGRRRPDLPAPELWTELTGLAASSEPEDGSEGAAEGRAAAVSLEEALLRLAEFLSVQLGAEESCGGPADLGQSGEVPSLLTVTSQLLALLAWLRSPRGRQALLQGTQPAPRVRPPSPDGSTSQEESPSHFTAVPGEPLGDETQGQQPLQLEEDQRAWQRLEQLILGQLEELKQQLEQQEEELGRLRLGVGATDSEKRVQHLTLENEALKQSLSLMRDLLLHWGPGPPIRAPQEEAEALLELQGRLQEAQDTTEALRAQLGVQEVQLQGLQGALQQLQQETEQNCRRELQQMHGQLAGLRARMASLRQGCGDLRGLVSTFTQSCQGSLSEARGQVSWALGALSSGGPGTQLPEGQQGPPAGCPGRLPELKGNIRVLCRLRPGTSSSLVSVEPGPGGTVTTCYRGRHRRFRLDWVFPPDASQEEVFRELEPAVLSCLRGYSVCIFTYGQTGTGKTYSMEGPPEDPGIVPRALQSLFREMGAGRQHRVTLSMVEIYNEAVRDLLAPGPPERLAVRQGPEGQGGIQVAGLTHWDVPNLETLHQMLKLGRSNRATAATAMNQRSSRSHALVTLTLRAASPPRAPGTAGTLHLVDLAGSERARKAGAAGPPRGDPDGARRLREAQTINRSLLALGGVMAALRAHRPHVPFRDSQLTRLLQPALGPGTTAVLLLQVGAGAGQVCACRSPPTRARPPAPLARRSPRGRRISGRQSAPSSSPTEWVKWSWGQPGAAGSRAPPGRLLPSAPTLRSPGPPAPLRRPLAVLHAPVPTTARARLSRPQRACPSSPGSRPCPWGLRPGLCWQRR", "length": 838 }, "evidence": [ { "id": "E1BM50", "url": "https://omabrowser.org/oma/group/E1BM50/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BM50", "url": "https://www.uniprot.org/uniprotkb/E1BM50" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BM50", "url": "https://www.uniprot.org/uniprotkb/E1BM50" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "E1BM50", "url": "https://www.uniprot.org/uniprotkb/E1BM50" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "E1BM50", "url": "https://www.uniprot.org/uniprotkb/E1BM50" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "E1BM50", "url": "https://www.uniprot.org/uniprotkb/E1BM50" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "E1BM50", "url": "https://www.uniprot.org/uniprotkb/E1BM50" } ], "pmid": "" }, { "name": "microtubule-based process", "id": "GO:0007017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", "evidence": [ { "database": "UniProtKB", "id": "E1BM50", "url": "https://www.uniprot.org/uniprotkb/E1BM50" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM50-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 830, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM50-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM50" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM50" }, { "id": "PS50067", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinesin motor", "eco_id": "ECO_0000259", "start_pos": 449, "end_pos": 770, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 785, 803 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 700, "end_pos": 702 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NJ24-1", "uniprot_ac": "A0ABI0NJ24", "uniprot_id": "A0ABI0NJ24_BOVIN", "mass": { "chemical_mass": 91396.0, "monoisotopic_mass": 91396.0 }, "refseq": {}, "gene_names": [ { "name": "IL4R", "type": "recommended", "evidence": [ { "id": "A0ABI0NJ24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ24" } ] } ], "protein_names": [ { "name": "Interleukin 4 receptor", "type": "synonym", "evidence": [ { "id": "A0ABI0NJ24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ24/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. 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"E1BN79_BOVIN", "mass": { "chemical_mass": 64339.0, "monoisotopic_mass": 64339.0 }, "refseq": { "ac": "NP_001179288", "name": "carboxylesterase 5A precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179288" }, "gene_names": [ { "name": "CES5A", "type": "recommended", "evidence": [ { "id": "E1BN79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN79" } ] }, { "name": "CES5A", "type": "synonym", "evidence": [ { "id": "NP_001179288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179288" } ] }, { "name": "CES7", "type": "synonym", "evidence": [ { "id": "NP_001179288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179288" } ] } ], "protein_names": [ { "name": "Carboxylic ester hydrolase", "type": "recommended", "evidence": [ { "id": "E1BN79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN79/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.-", "type": "synonym", "evidence": [ { "id": "E1BN79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN79/entry#names_and_taxonomy" } ] }, { "name": "carboxylesterase 5A precursor", "type": "synonym", "evidence": [ { "id": "NP_001179288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179288" } ] }, { "name": "carboxylesterase 7", "type": "synonym", "evidence": [ { "id": "NP_001179288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179288" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN79", "url": "https://www.uniprot.org/uniprotkb/E1BN79" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CES5A", "url": "https://www.uniprot.org/uniprotkb/E1BN79", "locus": { "chromosome": "18", "start_pos": 24711093, "end_pos": 24642086, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011164", "url": "https://www.ensembl.org/id/ENSBTAG00000011164" } ] } } ], "crossref": [ { "id": "E1BN79", "url": "https://alphafold.ebi.ac.uk/entry/E1BN79", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011164", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011164", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00312", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513992", "url": "https://www.ncbi.nlm.nih.gov/gene/513992", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513992", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513992", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HWIQQSP", "url": "https://omabrowser.org/oma/group/HWIQQSP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN79", "url": "https://www.orthodb.org/?gene=E1BN79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179288", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S057", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S057", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S057-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S057-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY83", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY83-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJX3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJX3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSR8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSR8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN79", "url": "https://www.uniprot.org/uniprotkb/E1BN79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN79-1", "url": "https://www.uniprot.org/uniprotkb/E1BN79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGEWVHPGQTLIWAVWVLAAATKGPATADAPARHTNLGWVQGTQASVLGNDMLVNVFLGVPYAAPPVGPLRFAKPEPLLPWDGFLNATSYPKLCFQNSEWLFTDQHILKVHYPKFRVSEDCLYLNIYAPAHAETGSKLPVMVWLPGGAFETGSASIFDGSALASYEDVLVVTIQYRLGIFGFFNTGDEHARGNWAFMDQVAALIWVQENIEFFGGDPRCVTIFGESAGAISVSSLILSPMTKGLFHRAIMESGVAIIPYLKAPDYERNDDLQTIASICDCSASDSIALLQCLRAKSSKELLSINQKTKSFTRVVDGLFFPNEPLDLLAQKLFHLVPSIIGVNNHECGFLLPMKEFPEILWGSNKSLALQLIHSVLHIPVQYLYLVANEYFHNKHSLVDIRNRFLDLLGDVFFVIPGLVTAQYHTDAGAPVYFYEFQHRPQCLKDRKPSFVKADHTDEIRFVFGGAFLKGNIVMFEEATEEEKGLSRKMMRYWANFARTGNPNGKGLPLWPAYRQSEEYLQLDLNISVGQRLKELELKFWTETLPLMMTSSGALLASLSSSTFLFLLLPFIFSFAP", "length": 576, "header": "tr|E1BN79-1|E1BN79_BOVIN Isoform 1 of Carboxylic ester hydrolase OS=Bos taurus OX=9913 GN=CES5A PE=3 SV=1 CANONICAL=E1BN79-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S057-1", "url": "https://www.uniprot.org/uniprotkb/E1BN79/entry#A0AAA9S057-1", "sequence": { "sequence": "MSGEWVHPGQTLIWAVWVLAAATKGPATADAPARHTNLGWVQGTQASVLGNDMLVNVFLGVPYAAPPVGPLRFAKPEPLLPWDGFLNATSYPKLCFQNSEWLFTDQHILKVHYPKFRVSEDCLYLNIYAPAHAETGSKLPVMVWLPGGAFETGSASIFDGSALASYEDVLVVTIQYRLGIFGFFNTGDEHARGNWAFMDQVAALIWVQENIEFFGGDPRCVTIFGESAGAISVSSLILSPMTKGLFHRAIMESGVAIIPYLKAPDYERNDDLQTIASICDCSASDSIALLQCLRAKSSKELLSINQKTKSFTRVVDGLFFPNEPLDLLAQKLFHLVPSIIGVNNHECGFLLPMKEFPEILWGSNKSLALQLIHSVLHIPVQYLYLVANEYFHNKHSLVDIRNRFLDLLGDVFFVIPGLVTAQYHTEEATEEEKGLSRKMMRYWANFARTGNPNGKGLPLWPAYRQSEEYLQLDLNISVGQRLKELELKFWTETLPLMMTSSGALLASLSSSTFLFLLLPFIFSFAP", "length": 526, "header": "tr|A0AAA9S057-1|E1BN79_BOVIN Computationally mapped isoform of Carboxylic ester hydrolase OS=Bos taurus OX=9913 GN=CES5A PE=3 SV=1 CANONICAL=E1BN79-1" }, "locus": { "chromosome": "18", "start_pos": 24710850, "end_pos": 24682781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128059.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128059.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078320.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078320.1" } ] } }, { "isoform_ac": "A0AAA9SY83-1", "url": "https://www.uniprot.org/uniprotkb/E1BN79/entry#A0AAA9SY83-1", "sequence": { "sequence": "MGDDLSWRSLLLYTEILSPMTKGLFHRAIMESGVAIIPYLKAPDYERNDDLQTIASICDCSASDSIALLQCLRAKSSKELLSINQKTKSFTRVVDGLFFPNEPLDLLAQKLFHLVPSIIGVNNHECGFLLPMEFPEILWGSNKSLALQLIHSVLHIPVQYLYLVANEYFHNKHSLVDIRNRFLDLLGDVFFVIPGLVTAQYHTDAGAPVYFYEFQHRPQCLKDRKPSFVKADHTDEIRFVFGGAFLKGNIVMFEEATEEEKGLSRKMMRYWANFARTGNPNGKGLPLWPAYRQSEEYLQLDLNISVGQRLKELELKFWTETLPLMMTSSGALLASLSSSTFLFLLLPFIFSFAP", "length": 354, "header": "tr|A0AAA9SY83-1|E1BN79_BOVIN Computationally mapped isoform of Carboxylic ester hydrolase OS=Bos taurus OX=9913 GN=CES5A PE=3 SV=1 CANONICAL=E1BN79-1" }, "locus": { "chromosome": "18", "start_pos": 24710850, "end_pos": 24642086, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089491.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089491.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089046.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089046.1" } ] } }, { "isoform_ac": "A0ABI0NJX3-1", "url": "https://www.uniprot.org/uniprotkb/E1BN79/entry#A0ABI0NJX3-1", "sequence": { "sequence": "MRCFQNSEWLFTDQHILKVHYPKFRVSEDCLYLNIYAPAHAETGSKLPVMVWLPGGAFETGSASIFDGSALASYEDVLVVTIQYRLGIFGFFNTGDEHARGNWAFMDQVAALIWVQENIEFFGGDPRCVTIFGESAGAISVSSLILSPMTKGLFHRAIMESGVAIIPYLKAPDYERNDDLQTIASICDCSASDSIALLQCLRAKSSKELLSINQKTKSFTRVVDGLFFPNEPLDLLAQKLFHLVPSIIGVNNHECGFLLPMKEFPEILWGSNKSLALQLIHSVLHIPVQYLYLVANEYFHNKHSLVDIRNRFLDLLGDVFFVIPGLVTAQYHTDAGAPVYFYEFQHRPQCLKDRKPSFVKADHTDEIRFVFGGAFLKGNIVMFEEATEEEKGLSRKMMRYWANFARTGRSTGSKVVPYLHYCLFVLQTHFWKITSLLQQYR", "length": 441, "header": "tr|A0ABI0NJX3-1|A0ABI0NJX3_BOVIN Computationally mapped isoform of Carboxylic ester hydrolase OS=Bos taurus OX=9913 GN=CES5A PE=3 SV=1 CANONICAL=E1BN79-1" }, "locus": { "chromosome": "18", "start_pos": 24718711, "end_pos": 24608146, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141599.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141599.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104557.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104557.1" } ] } }, { "isoform_ac": "A0ABI0NSR8-1", "url": "https://www.uniprot.org/uniprotkb/E1BN79/entry#A0ABI0NSR8-1", "sequence": { "sequence": "MSGEWVHPGQTLIWAVWVLAAATKGPATADAPARHTNLGWVQGTQASVLGNDMLVNVFLGVPYAAPPVGPLRFAKPEPLLPWDGFLNATSYPKLCFQNSEWLFTDQHILKVHYPKFRVSEDCLYLNIYAPAHAETGSKLPVMVWLPGGAFETGSASIFDGSALASYEDVLVVTIQYRLGIFGFFNTGDEHARGNWAFMDQVAALIWVQENIEFFGGDPRCVTIFGESAGAISVSSLILSPMTKGLFHRAIMESGVAIIPYLKAPDYERNDDLQTIASICDCSASDSIALLQCLRAKSSKELLSINQKTKSFTRVVDGLFFPNEPLDLLAQKLFHLVPSIIGVNNHECGFLLPMKEFPEILWGSNKSLALQLIHSVLHIPVQYLYLVANEYFHNKHSLVDIRNRFLDLLGDVFFVIPGLVTAQYHTDAGAPVYFYEFQHRPQCLKDRKPSFVKADHTDEIRFVFGGAFLKGNIVMFGFPASLPGEKGK", "length": 487, "header": "tr|A0ABI0NSR8-1|A0ABI0NSR8_BOVIN Computationally mapped isoform of Carboxylic ester hydrolase OS=Bos taurus OX=9913 GN=CES5A PE=3 SV=1 CANONICAL=E1BN79-1" }, "locus": { "chromosome": "18", "start_pos": 24737936, "end_pos": 24682781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142788.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142788.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106233.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106233.1" } ] } }, { "isoform_ac": "E1BN79-1", "url": "https://www.uniprot.org/uniprotkb/E1BN79/entry#E1BN79-1", "sequence": { "sequence": "MSGEWVHPGQTLIWAVWVLAAATKGPATADAPARHTNLGWVQGTQASVLGNDMLVNVFLGVPYAAPPVGPLRFAKPEPLLPWDGFLNATSYPKLCFQNSEWLFTDQHILKVHYPKFRVSEDCLYLNIYAPAHAETGSKLPVMVWLPGGAFETGSASIFDGSALASYEDVLVVTIQYRLGIFGFFNTGDEHARGNWAFMDQVAALIWVQENIEFFGGDPRCVTIFGESAGAISVSSLILSPMTKGLFHRAIMESGVAIIPYLKAPDYERNDDLQTIASICDCSASDSIALLQCLRAKSSKELLSINQKTKSFTRVVDGLFFPNEPLDLLAQKLFHLVPSIIGVNNHECGFLLPMKEFPEILWGSNKSLALQLIHSVLHIPVQYLYLVANEYFHNKHSLVDIRNRFLDLLGDVFFVIPGLVTAQYHTDAGAPVYFYEFQHRPQCLKDRKPSFVKADHTDEIRFVFGGAFLKGNIVMFEEATEEEKGLSRKMMRYWANFARTGNPNGKGLPLWPAYRQSEEYLQLDLNISVGQRLKELELKFWTETLPLMMTSSGALLASLSSSTFLFLLLPFIFSFAP", "length": 576, "header": "tr|E1BN79-1|E1BN79_BOVIN Isoform 1 of Carboxylic ester hydrolase OS=Bos taurus OX=9913 GN=CES5A PE=3 SV=1 CANONICAL=E1BN79-1" }, "locus": { "chromosome": "18", "start_pos": 24710850, "end_pos": 24682781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014830.5", "url": "https://www.ensembl.org/id/ENSBTAT00000014830.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014830.3", "url": "https://www.ensembl.org/id/ENSBTAP00000014830.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:513992", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513992", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5GRG2-1", "protein_name": "Carboxylesterase 5A", "gene_name": "Ces5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDWVHTGQALIWVLWIFAAIIRGSVTEEPHRYTRLGWVQGKQATVLGRLEPVNVFLGIPFAAPPLGPLRFSNPQPPIPWHDLREATTYPNVCFQNLEWLFIYQNLLKVHYPKLGVSEDCLYLNIYAPAYANDGSRLPVMMWIPGGGFETGSASIFDGSALAAYEDVLIVTIQYRLGIFGFFNTQNQHAPGNWAFQDQLAALQWVRENINYFGGNPDSVTIFGGSAGAISISSLILSPLSAGLFHRAIMQSGVAIIPSLKNFDDELKHGLQVVADVCKCNVSDSKVLLKCLREKSSLELLSLGQKTKAFTRVVDGSFFPEEPMELLSQKTFKTVPSIIGVNNQECGYILPMREAPEILFGSNESTALTLIHVLLHIPPQYMHIVAKDYFHGKHSLTDIRDTLLDLFGDVFFVVPGLVTARNHRDADGPVYFYEFQHRPNCFQNTRPAFVKADHTDEIRFVFGGPFLEGDVVMFEEATEDEKLLSRKMMSYWANFARSGDPNGDDLPLWPAYDQNESYLKLDVNISTGWRLKDRRVEFWTDTLPLIMSASKALLSPTFPLILFSLLPPSLLSIAS", "length": 575 }, "evidence": [ { "id": "E1BN79", "url": "https://omabrowser.org/oma/group/E1BN79/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AW46-1", "protein_name": "Carboxylesterase 5A", "gene_name": "Ces5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGDWVRPGQALIWVIWIFGAIIEGSVTEEPHRYTKLGWVQGKQATVLGRLEPVNVFLGIPFAAPPLGPLRFSKPQPPIPWDNLREATAYPNLCFQNLEWLFIYQNLLKVSYPILGMSEDCLYLNIYAPCHANNGSSLPVMVWIPGGGFETGSASIFDGSALAVYEDVLVVTIQYRLGIFGFFTTQNQHAPGNWAFWDQLAALLWVRENIKYFGGNPDSVTIFGNSAGAISISSLILSPLSADLFHRAIMQSGVAIIPSLKSSDNDLKHDLQVVANVCDCNVSDSKALLKCLREKSSLELMSLSQKAKSFTRVVDGSFFSEEPLELLSQKTLKIVPSIIGVNNQECGYILPVRDTPEILLGSNESTALTLIHTLLHIPTQHLYIVTKEYFHGKHSPTDIRDTLLDLFGDVFFVVPGLVTARYHRDSGGPVYFYEFQHRPHCFQNSRPAFVKADHTDEIRFVFGGPFLKGDVVMFEEATEEEKLLSRKMMKYWANFARSGDPNGADLPPWPVYDENEQYLELDVNISTGRRLKDQRVEFWTDTLPLILSASKALLSPTFSLILLSLLSPVLLSAAS", "length": 575 }, "evidence": [ { "id": "E1BN79", "url": "https://omabrowser.org/oma/group/E1BN79/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6NT32-1", "protein_name": "Carboxylesterase 5A", "gene_name": "CES5A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTSTIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP", "length": 575 }, "evidence": [ { "id": "E1BN79", "url": "https://omabrowser.org/oma/group/E1BN79/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1BN79", "url": "https://www.uniprot.org/uniprotkb/E1BN79" } ], "pmid": "" }, { "name": "carboxylesterase activity", "id": "GO:0106435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106435", "evidence": [ { "database": "UniProtKB", "id": "E1BN79", "url": "https://www.uniprot.org/uniprotkb/E1BN79" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 525, "end_pos": 527, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN79-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 576, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN79-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN79" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN79" }, { "id": "PF00135", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carboxylesterase type B", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 540, "start_aa": "Ala", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 364, "end_pos": 366 }, { "start_pos": 525, "end_pos": 527 }, { "start_pos": 87, 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"https://www.ebi.ac.uk/interpro/entry/IPR015424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EHTFVDM", "url": "https://omabrowser.org/oma/group/EHTFVDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNH2", "url": "https://www.orthodb.org/?gene=E1BNH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11808", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11808", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11808:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11808:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "14005", "url": "https://www.rhea-db.org/rhea/14005", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "14501", "url": "https://www.rhea-db.org/rhea/14501", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "24923", "url": "https://www.rhea-db.org/rhea/24923", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "24931", "url": "https://www.rhea-db.org/rhea/24931", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "31151", "url": "https://www.rhea-db.org/rhea/31151", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S2Y7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP66", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP66-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTD0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTD0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTW7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTW7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH2", "url": "https://www.uniprot.org/uniprotkb/E1BNH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQEKEASPHGFLPRFQHFATQAIHVGQEPEQWTSQAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYSLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVATEFGLKISFVDCSKPKLLEAAITPETKLVWIETPTNPSLKMIDIEACAHTVHKHGDIILVVDNTFMSAYFQRPLSLGADICMYSATKYMNGHSDVVMGLVSLNSESLHDRLRFLQNSLGAVPSPIDCYLCNRGLKTLQVRMEKHFENGMAVAQFLESNPQVEKVIYPGLPSHPQHELAKRQCTGCPGMVTFYIKGSLQHAETFLQNLKLFTLAESLGGYESLAELPAIMTHASVPKSDREVLGISDTLIRLSVGLEDKQDLLDDLDQALKAANPPNASSN", "length": 405, "header": "tr|E1BNH2-1|E1BNH2_BOVIN Isoform 1 of Cystathionine gamma-lyase OS=Bos taurus OX=9913 GN=CTH PE=3 SV=2 CANONICAL=E1BNH2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S2Y7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH2/entry#A0AAA9S2Y7-1", "sequence": { "sequence": "MQEKEASPHGFLPRFQHFATQAIHVGQEPEQWTSQAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYSLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVATEFGLKISFVDCSKPKLLEAAITPETKLVWIETPTNPSLKMIDIEACAHTVHKHGDIILVVDNTFMSAYFQRPLSLGADICMYSATKYMNGHSDVVMGLVSLNSESLHDRLRFLQNSLGAVPSPIDCYLCNRGLKTLQVRMEKHFENGMAVAQFLESNPQVEKVIYPGLPSHPQHELAKRQCTGCPGMVTFYIKGSLQHAETFLQNLKLFTLAESLGGYESLAELPAIMTHASVPKSDREVLGISDTLIRLSVGLEDKQDLLDDLDQALKAATGSK", "length": 401, "header": "tr|A0AAA9S2Y7-1|E1BNH2_BOVIN Computationally mapped isoform of Cystathionine gamma-lyase OS=Bos taurus OX=9913 GN=CTH PE=3 SV=1 CANONICAL=E1BNH2-1" }, "locus": { "chromosome": "3", "start_pos": 74793584, "end_pos": 74742829, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122259.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122259.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079448.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079448.1" } ] } }, { "isoform_ac": "A0AAA9TP66-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH2/entry#A0AAA9TP66-1", "sequence": { "sequence": "MQEKEASPHGFLPRFQHFATQAIHVGQEPEQWTSQAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYSLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVATEFGLKISFVDCSKPKLLEAAITPETKRPLSLGADICMYSATKYMNGHSDVVMGLVSLNSESLHDRLRFLQNSLGAVPSPIDCYLCNRGLKTLQVRMEKHFENGMAVAQFLESNPQVEKVIYPGLPSHPQHELAKRQCTGCPGMVTFYIKGSLQHAETFLQNLKLFTLAESLGGYESLAELPAIMTHASVPKSDREVLGISDTLIRLSVGLEDKQDLLDDLDQALKAANPPNASSN", "length": 361, "header": "tr|A0AAA9TP66-1|E1BNH2_BOVIN Computationally mapped isoform of Cystathionine gamma-lyase OS=Bos taurus OX=9913 GN=CTH PE=3 SV=1 CANONICAL=E1BNH2-1" }, "locus": { "chromosome": "3", "start_pos": 74793584, "end_pos": 74767179, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112205.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112205.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100342.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100342.1" } ] } }, { "isoform_ac": "A0AAA9TTD0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH2/entry#A0AAA9TTD0-1", "sequence": { "sequence": "MQEKEASPHGFLPRFQHFATQAIHVGQEPEQWTSQAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYSLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVATEFGLKISFVDCSKPKLLEAAITPETKLVWIETPTNPSLKMIDIEACAHTVHKHGDIILVVDNTFMSAYFQRPLSLGADICMYSATKYMNGHSDVVMGLVSLNSESLHDRLRFLQNSLGAVPSPIDCYLCNRGLKTLQVRMEKHFENGMAVAQFLESNPQVEKVIYPGLPSHPQHELAKRQCTGCPGMVTFYIKGSLQHAETFLQNLKLFTLAESLGGYESLAELPAIMTHASVPKSDREVLGISDTLIRLSVGLEDKQDLLDDLDQALKAA", "length": 397, "header": "tr|A0AAA9TTD0-1|E1BNH2_BOVIN Computationally mapped isoform of Cystathionine gamma-lyase OS=Bos taurus OX=9913 GN=CTH PE=3 SV=1 CANONICAL=E1BNH2-1" }, "locus": { "chromosome": "3", "start_pos": 74793584, "end_pos": 74767489, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103256.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103256.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101890.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101890.1" } ] } }, { "isoform_ac": "A0AAA9TTW7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH2/entry#A0AAA9TTW7-1", "sequence": { "sequence": "MQEKEASPHGFLPRFQHFATQAIHVGQEPEQWTSQAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYSTNRYFRQVATEFGLKISFVDCSKPKLLEAAITPETKLVWIETPTNPSLKMIDIEACAHTVHKHGDIILVVDNTFMSAYFQRPLSLGADICMYSATKYMNGHSDVVMGLVSLNSESLHDRLRFLQNSLGAVPSPIDCYLCNRGLKTLQVRMEKHFENGMAVAQFLESNPQVEKVIYPGLPSHPQHELAKRQCTGCPGMVTFYIKGSLQHAETFLQNLKLFTLAESLGGYESLAELPAIMTHASVPKSDREVLGISDTLIRLSVGLEDKQDLLDDLDQALKAANPPNASSN", "length": 373, "header": "tr|A0AAA9TTW7-1|E1BNH2_BOVIN Computationally mapped isoform of Cystathionine gamma-lyase OS=Bos taurus OX=9913 GN=CTH PE=3 SV=1 CANONICAL=E1BNH2-1" }, "locus": { "chromosome": "3", "start_pos": 74793584, "end_pos": 74767179, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120391.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120391.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099983.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099983.1" } ] } }, { "isoform_ac": "E1BNH2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH2/entry#E1BNH2-1", "sequence": { "sequence": "MQEKEASPHGFLPRFQHFATQAIHVGQEPEQWTSQAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYSLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVATEFGLKISFVDCSKPKLLEAAITPETKLVWIETPTNPSLKMIDIEACAHTVHKHGDIILVVDNTFMSAYFQRPLSLGADICMYSATKYMNGHSDVVMGLVSLNSESLHDRLRFLQNSLGAVPSPIDCYLCNRGLKTLQVRMEKHFENGMAVAQFLESNPQVEKVIYPGLPSHPQHELAKRQCTGCPGMVTFYIKGSLQHAETFLQNLKLFTLAESLGGYESLAELPAIMTHASVPKSDREVLGISDTLIRLSVGLEDKQDLLDDLDQALKAANPPNASSN", "length": 405, "header": "tr|E1BNH2-1|E1BNH2_BOVIN Isoform 1 of Cystathionine gamma-lyase OS=Bos taurus OX=9913 GN=CTH PE=3 SV=2 CANONICAL=E1BNH2-1" }, "locus": { "chromosome": "3", "start_pos": 74793584, "end_pos": 74767179, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019679.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019679.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019679.5", "url": "https://www.ensembl.org/id/ENSBTAP00000019679.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P55217-1", "protein_name": "Cystathionine gamma-synthase 1, chloroplastic", "gene_name": "CGS1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAVSSFQCPTIFSSSSISGFQCRSDPDLVGSPVGGSSRRRVHASAGISSSFTGDAGLSSRILRFPPNFVRQLSIKARRNCSNIGVAQIVAAKWSNNPSSALPSAAAAAATSSASAVSSAASAAAASSAAAAPVAAAPPVVLKSVDEEVVVAEEGIREKIGSVQLTDSKHSFLSSDGSLTVHAGERLGRGIVTDAITTPVVNTSAYFFKKTAELIDFKEKRSVSFEYGRYGNPTTVVLEDKISALEGAESTLVMASGMCASTVMLLALVPAGGHIVTTTDCYRKTRIFMENFLPKLGITVTVIDPADIAGLEAAVNEFKVSLFFTESPTNPFLRCVDIELVSKICHKRGTLVCIDGTFATPLNQKALALGADLVVHSATKYIGGHNDVLAGCICGSLKLVSEIRNLHHVLGGTLNPNAAYLIIRGMKTLHLRVQQQNSTAFRMAEILEAHPKVSHVYYPGLPSHPEHELAKRQMTGFGGVVSFEIDGDIETTIKFVDSLKIPYIAPSFGGCESIVDQPAIMSYWDLPQEERLKYGIKDNLVRFSFGVEDFEDVKADILQALEAI", "length": 563 }, "evidence": [ { "id": "E1BNH2", "url": "https://omabrowser.org/oma/group/E1BNH2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "E1BNH2", "url": "https://www.uniprot.org/uniprotkb/E1BNH2" } ], "pmid": "" }, { "name": "homocysteine desulfhydrase activity", "id": "GO:0047982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047982", "evidence": [ { "database": "UniProtKB", "id": "E1BNH2", "url": "https://www.uniprot.org/uniprotkb/E1BNH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transsulfuration", "id": "GO:0019346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019346", "evidence": [ { "database": "UniProtKB", "id": "E1BNH2", "url": "https://www.uniprot.org/uniprotkb/E1BNH2" } ], "pmid": "" }, { "name": "cysteine biosynthetic process", "id": "GO:0019344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019344", "evidence": [ { "database": "UniProtKB", "id": "E1BNH2", "url": "https://www.uniprot.org/uniprotkb/E1BNH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14005", "name": "", "equation": "L,L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M2L1-1", "E1BNH2-1", "Q58DW2-1" ], "evidence": [ { "id": "14005", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14005" } ] }, { "id": "14501", "name": "", "equation": "L-homocysteine + H2O = 2-oxobutanoate + hydrogen sulfide + NH4(+) + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M2L1-1", "E1BNH2-1" ], "evidence": [ { "id": "14501", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14501" } ] }, { "id": "24923", "name": "", "equation": "L-homoserine = 2-oxobutanoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M2L1-1", "E1BNH2-1" ], "evidence": [ { "id": "24923", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24923" } ] }, { "id": "24931", "name": "", "equation": "L-cysteine + H2O = hydrogen sulfide + pyruvate + NH4(+) + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M2L1-1", "E1BNH2-1" ], "evidence": [ { "id": "24931", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24931" } ] }, { "id": "31151", "name": "", "equation": "L-selenocystathionine + H2O = L-selenocysteine + 2-oxobutanoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M2L1-1", "E1BNH2-1" ], "evidence": [ { "id": "31151", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/31151" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M2L1", "gene_name": "", "activity": [ { "ec_number": "4.4.1.1", "activity": "L,L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4(+).", "evidence": [ { "id": "A0A3Q1M2L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2L1" } ] }, { "ec_number": "4.4.1.2", "activity": "L-homocysteine + H2O = 2-oxobutanoate + hydrogen sulfide + NH4(+) + H(+).", "evidence": [ { "id": "A0A3Q1M2L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2L1" } ] }, { "ec_number": "4.4.1.2", "activity": "", "evidence": [ { "id": "A0A3Q1M2L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2L1" } ] }, { "ec_number": "4.4.1.1", "activity": "", "evidence": [ { "id": "A0A3Q1M2L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2L1" } ] } ] }, { "uniprot_ac": "E1BNH2", "gene_name": "CTH", "activity": [ { "ec_number": "4.4.1.1", "activity": "L,L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4(+).", "evidence": [ { "id": "E1BNH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH2" } ] }, { "ec_number": "4.4.1.2", "activity": "L-homocysteine + H2O = 2-oxobutanoate + hydrogen sulfide + NH4(+) + H(+).", "evidence": [ { "id": "E1BNH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH2" } ] }, { "ec_number": "4.4.1.1", "activity": "", "evidence": [ { "id": "E1BNH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH2" } ] }, { "ec_number": "4.4.1.2", "activity": "", "evidence": [ { "id": "E1BNH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH2" } ] } ] }, { "uniprot_ac": "Q58DW2", "gene_name": "CTH", "activity": [ { "ec_number": "4.4.1.1", "activity": "L,L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4(+).", "evidence": [ { "id": "Q58DW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DW2" } ] }, { "ec_number": "4.4.1.1", "activity": "", "evidence": [ { "id": "Q58DW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DW2" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNH2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 405, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNH2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNH2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.4.1.1", "ec_name": "L,L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4(+).", "evidence": [ { "id": "4.4.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.1" }, { "id": "4.4.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.4.1.1" } ] }, { "ec_number": "4.4.1.2", "ec_name": "L-homocysteine + H2O = 2-oxobutanoate + hydrogen sulfide + NH4(+) + H(+).", "evidence": [ { "id": "4.4.1.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 401, "end_pos": 403 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM45-1", "uniprot_ac": "E1BM45", "uniprot_id": "E1BM45_BOVIN", "mass": { "chemical_mass": 105381.0, "monoisotopic_mass": 105381.0 }, "refseq": { "ac": "NP_001179535", "name": "GPI ethanolamine phosphate transferase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179535" }, "gene_names": [ { "name": "PIGN", "type": "recommended", "evidence": [ { "id": "E1BM45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM45" } ] }, { "name": "PIGN", "type": "synonym", "evidence": [ { "id": "NP_001179535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179535" } ] } ], "protein_names": [ { "name": "GPI ethanolamine phosphate transferase 1", "type": "recommended", "evidence": [ { "id": "E1BM45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM45/entry#names_and_taxonomy" } ] }, { "name": "2.-.-.-", "type": "synonym", "evidence": [ { "id": "E1BM45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM45/entry#names_and_taxonomy" } ] }, { "name": "GPI ethanolamine phosphate transferase 1", "type": "synonym", "evidence": [ { "id": "NP_001179535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179535" } ] } ], "function": [ { "annotation": "Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S7H6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7H6#function" }, { "database": "UniProtKB", "id": "RU367138", "url": "https://www.uniprot.org/uniprotkb/RU367138#function" }, { "database": "UniProtKB", "id": "A0AAA9SJN7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJN7#function" }, { "database": "UniProtKB", "id": "A0AAA9SPR4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPR4#function" }, { "database": "UniProtKB", "id": "A0A3Q1MAR4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR4#function" }, { "database": "UniProtKB", "id": "A0A3Q1LV52", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV52#function" }, { "database": "UniProtKB", "id": "A0A3Q1LMK2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMK2#function" }, { "database": "UniProtKB", "id": "E1BM45", "url": "https://www.uniprot.org/uniprotkb/E1BM45#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM45", "url": "https://www.uniprot.org/uniprotkb/E1BM45" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PIGN", "url": "https://www.uniprot.org/uniprotkb/E1BM45", "locus": { "chromosome": "24", "start_pos": 60492609, "end_pos": 60601481, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016663", "url": "https://www.ensembl.org/id/ENSBTAG00000016663" } ] } } ], "crossref": [ { "id": "E1BM45", "url": "https://alphafold.ebi.ac.uk/entry/E1BM45", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016663", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016663", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16020", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16020", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "525095", "url": "https://www.ncbi.nlm.nih.gov/gene/525095", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:525095", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525095", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QSYFHRE", "url": "https://omabrowser.org/oma/group/QSYFHRE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMK2", "url": "https://www.orthodb.org/?gene=A0A3Q1LMK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LV52", "url": "https://www.orthodb.org/?gene=A0A3Q1LV52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MAR4", "url": "https://www.orthodb.org/?gene=A0A3Q1MAR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BM45", "url": "https://www.orthodb.org/?gene=E1BM45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12250", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12250", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12250:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12250:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04987", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04987", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-162710", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-162710", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179535", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMK2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LV52", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LV52-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAR4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7H6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7H6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJN7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJN7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPR4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPR4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM45", "url": "https://www.uniprot.org/uniprotkb/E1BM45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM45-1", "url": "https://www.uniprot.org/uniprotkb/E1BM45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLYITLGLLVHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLMLFVADGLRADKLYELDEDGNSRAPFVRNIIMNEGSWGISHTRVPTESRPGHVAMIAGFYEDVSAVAKGWKENPVEFDSLLNETRYTWSWGSPDILAMFAKGDLRSHIFTESYDASSEDFGAHDVTKLDTWVFDHVKEFFHAARNNQSLFSKVNEDKIVFFLHLLGIDTNGHAHRPSSREYSDNIKLVDKELKEIESTVKDFYGNDGKTAFIFTADHGMTDWGSHGAGHPLETCTPFIAWGAGIRLPQKVSAQKFDDSYLQEWKLENWKRQDINQADVAPLMAALIGVPFPLNSVGIIPVDMLNTSDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKSLSDTKQANILRKARYYIKQKKYDEAVSLCRQLIHLALRGLAYYHTYDRFFLAFNVVLGFVGWTSYASLLIIKSHCNLMRGVSTEAKNPSRLLPCAFGAVGVSVTFFLLIQACPWTYYVYCLLPLPIWYAVLREIPVIQGFVTLLSTFPPRRFLGYLLLFILGVEVLVLSFFYRYMLTAGLVALAAWPFITALWTRAKSISLSWIFFCLLLAVFPLMPVVGRKPDIFLVVGAGLLVLLLSLFVVTSVIKRKDSFINEELVLHLLQMLSVMFSMCVVYGTHHSLLKKQGLPLLNQIVSWTILASSFVMPLLSPPVLFDRLFSILVSSMSTYLLLSTGYEALFPLVLSCLMFVWIHMEQETLQHSVVSCKQKVSTIQFACNTDAAQCRDLCLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDPSSVYCFLTVFSPFKMGALIMWKILIPFVLVMCAFEAVQVTTQLSSKSLFLMVINISDIMALHFFFLIKDYGSWLDIGTSISHYVIVMSMTIFMVFLNCLAQMLTTRKLSLCGRPKSHVI", "length": 931, "header": "tr|E1BM45-1|E1BM45_BOVIN Isoform 1 of GPI ethanolamine phosphate transferase 1 OS=Bos taurus OX=9913 GN=PIGN PE=3 SV=2 CANONICAL=E1BM45-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMK2-1", "url": "https://www.uniprot.org/uniprotkb/E1BM45/entry#A0A3Q1LMK2-1", "sequence": { "sequence": "MLLYITLGLLVHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLMLFVADGLRADKLYELDEDGNSRAPFVRNIIMNEGSWGISHTRVPTESRPGHVAMIAGFYEDVSAVAKGDLRSHIFTESYDASSEDFGAHDVTKLDTWVFDHVKEFFHAARNNQSLFSKVNEDKIVFFLHLLGIDTNGHAHRPSSREYSDNIKLVDKELKEIESTVKDFYGNDGKTAFIFTADHGMTDWGSHGAGHPLETCTPFIAWGAGIRLPQKVSAQKFDDSYLQEWKLENWKRQDINQADVAPLMAALIGVPFPLNSVGIIPVDMLNTSDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKSLSDTKQANILRKARYYIKQKKYDEAVSLCRQLIHLALRGLAYYHTYDRFFLAFNVVLGFVGWTSYASLLIIKSHCNLMRGVSTEAKNPSRLLPCAFGAVGVSVTFFLLIQACPWTYYVYCLLPLPIWYAVLREIPVIQGFVTLLSTFPPRRFLGYLLLFILGVEVLVLSFFYRYMLTAGLVALAAWPFITALWTRAKSISLSWIFFCLLLAVFPLMPVVGRKPDIFLVVGAGLLVLLLSLFVVTSVIKRKDSFINEELVLHLLQMLSVMFSMCVVYGTHHSLLKKQGLPLLNQIVSWTILASSFVMPLLSPPVLFDRLFSILVSSMSTYLLLSTGYEALFPLVLSCLMFVWIHMEQETLQHSVVSCKQKVSTIQFACNTDAAQCRDLCLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDPSSVYCFLTVFSPFKMGALIMWKILIPFVLVMCAFEAVQVTTQLSSKSLFLMVINISDIMALHFFFLIKDYGSWLDIGTSISHYVIVMSMTIFMVFLNCLAQMLTTRKLSLCGRPKSHVI", "length": 898, "header": "tr|A0A3Q1LMK2-1|E1BM45_BOVIN Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Bos taurus OX=9913 GN=PIGN PE=3 SV=2 CANONICAL=E1BM45-1" }, "locus": { "chromosome": "24", "start_pos": 60593232, "end_pos": 60494406, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075916.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075916.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058103.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058103.2" } ] } }, { "isoform_ac": "A0A3Q1LV52-1", "url": "https://www.uniprot.org/uniprotkb/E1BM45/entry#A0A3Q1LV52-1", "sequence": { "sequence": "MLLYITLGLLVHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLMLFVADGLRADKLYELDEDGNSRAPFVRNIIMNEGSWGISHTRVPTESRPGHVAMIAGFYEDVSAVAKGWKENPVEFDSLLNETRYTWSWGSPDILAMFAKGDLRSHIFTESYDASSEDFGAHDVTKLDTWVFDHVKEFFHAARNNQSLFSKVNEDKIVFFLHLLGIDTNGHAHRPSSREYSDNIKLVDKELKEIESTVKDFYGNDGKTAFIFTADHGMTDWGSHGAGHPLETCTPFIAWGAGIRLPQKVSAQKFDDSYLQEWKLENWKRQDINQGIIPVDMLNTSDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKSLSDTKQANILRKARYYIKQKKYDEAVSLCRQLIHLALRGLAYYHTYDRFFLAFNVVLGFVGWTSYASLLIIKSHCNLMRGVSTEAKNPSRLLPCAFGAVGVSVTFFLLIQACPWTYYVYCLLPLPIWYAVLREIPVIQGFVTLLSTFPPRRFLGYLLLFILGVEVLVLSFFYRYMLTAGLVALAAWPFITALWTRAKSISLSWIFFCLLLAVFPLMPVVGRKPDIFLVVGAGLLVLLLSLFVVTSVIKRKDSFINEELVLHLLQMLSVMFSMCVVYGTHHSLLKKQGLPLLNQIVSWTILASSFVMPLLSPPVLFDRLFSILVSSMSTYLLLSTGYEALFPLVLSCLMFVWIHMEQETLQHSVVSCKQKVSTIQFACNTDAAQCRDLCLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDPSSVYCFLTVFSPFKMGALIMWKILIPFVLVMCAFEAVQVTTQLSSKSLFLMVINISDIMALHFFFLIKDYGSWLDIGTSISHYVIVMSMTIFMVFLNCLAQMLTTRKLSLCGRPKSHVI", "length": 911, "header": "tr|A0A3Q1LV52-1|E1BM45_BOVIN Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Bos taurus OX=9913 GN=PIGN PE=3 SV=2 CANONICAL=E1BM45-1" }, "locus": { "chromosome": "24", "start_pos": 60593232, "end_pos": 60494406, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070081.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070081.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059136.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059136.2" } ] } }, { "isoform_ac": "A0A3Q1MAR4-1", "url": "https://www.uniprot.org/uniprotkb/E1BM45/entry#A0A3Q1MAR4-1", "sequence": { "sequence": "MLLYITLGLLVHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLMLFVADGLRADKLYELDEDGNSRAPFVRNIIMNEGSWGISHTRVPTESRPGHVAMIAGFYEDVSAVAKGWKENPVEFDSLLNETRYTWSWGSPDILAMFAKGDLRSHIFTESYDASSEDFGAHDVTKLDTWVFDHVKEFFHAARNNQSLFSKVNEDKIVFFLHLLGIDTNGHAHRPSSREYSDNIKLVDKELKEIESTVKDFYGNDGKTAFIFTADHGMTDWGSHGAGHPLETCTPFIAWGAGIRLPQKVSAQKFDDSYLQEWKLENWKRQDINQADVAPLMAALIGVPFPLNSVGIIPVDMLNTSDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKSLSDTKQANILRKARYYIKQKKYDEAVSLCRQLIHLALRGLAYYHTYDRFFLAFNVVLGFVGWTSYASLLIIKSHCNLMRGVSTEAKNPSRLLPCAFGAVGVSVTFFLLIQACPWTYYVYCLLPLPIWYAVLREIPVIQGFVTLLSTFPPRRFLGYLLLFILGVEVLVLSFFYRYMLTAGLVALAAWPFITALWTRAKSISLSWIFFCLLLAVFPLMPVVGRKPDIFLVVGAGLLVLLLSLFVVTSVIKRKDSFINEELVLHLLQMLSVMFSMCVVYGTHHSLLKKQGLPLLNQIVSWTILASSFVMPLLSPPVLFDRLFSILVSSMSTYLLLSTGYEALFPLVLSCLMFVWIHMEQETLQHSVVSCKQKVSTIQFACNTDAAQCRDLCLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDPSSVYCFLTVFSPFKMGALIMWKILIPFVLVMCAFEAVQVTTQLSSKRALKKRGPGKIELGRKNTK", "length": 877, "header": "tr|A0A3Q1MAR4-1|E1BM45_BOVIN Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Bos taurus OX=9913 GN=PIGN PE=3 SV=2 CANONICAL=E1BM45-1" }, "locus": { "chromosome": "24", "start_pos": 60593232, "end_pos": 60519572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080371.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080371.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065689.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065689.2" } ] } }, { "isoform_ac": "A0AAA9S7H6-1", "url": "https://www.uniprot.org/uniprotkb/E1BM45/entry#A0AAA9S7H6-1", "sequence": { "sequence": "MLLYITLGLLVHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLMLFVADGLRADKLYELDEDGNSRAPFVRNIIMNEGSWGISHTRVPTESRPGHVAMIAGFYEDVSAVAKGWKENPVEFDSLLNETRYTWSWGSPDILAMFAKGDLRSHIFTESYDASSEDFGAHDVTKLDTWVFDHVKEFFHAARNNQSLFSKVNEDKIVFFLHLLGIDTNGHAHRPSSREYSDNIKLVDKELKEIESTVKDFYGNDGKTAFIFTADHGMTDWGSHGAGHPLETCTPFIAWGAGIRLPQKVSAQKFDDSYLQEWKLENWKRQDINQADVAPLMAALIGVPFPLNSVGIIPVDMLNTSDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKSLSDTKQANILRKARYYIKQKKYDEANPSRLLPCAFGAVGVSVTFFLLIQACPWTYYVYCLLPLPIWYAVLREIPVIQGFVTLLSTFPPRRFLGYLLLFILGVEVLVLSFFYRYMLTAGLVALAAWPFITALWTRAKSISLSWIFFCLLLAVFPLMPVVGRKPDIFLVVGAGLLVLLLSLFVVTSVIKRKDSFINEELVLHLLQMLSVMFSMCVVYGTHHSLLKKQGLPLLNQIVSWTILASSFVMPLLSPPVLFDRLFSILVSSMSTYLLLSTGYEALFPLVLSCLMFVWIHMEQETLQHSVVSCKQKVSTIQFACNTDAAQCRDLCLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDPSSVYCFLTVFSPFKMGALIMWKILIPFVLVMCAFEAVQVTTQLSSKSLFLMVINISDIMALHFFFLIKDYGSWLDIGTSISHYVIVMSMTIFMVFLNCLAQMLTTRKLSLCGRPKSHVI", "length": 870, "header": "tr|A0AAA9S7H6-1|E1BM45_BOVIN Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Bos taurus OX=9913 GN=PIGN PE=3 SV=1 CANONICAL=E1BM45-1" }, "locus": { "chromosome": "24", "start_pos": 60593232, "end_pos": 60494406, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095618.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095618.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078114.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078114.1" } ] } }, { "isoform_ac": "A0AAA9SJN7-1", "url": "https://www.uniprot.org/uniprotkb/E1BM45/entry#A0AAA9SJN7-1", "sequence": { "sequence": "MLLYITLGLLVHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLMLFVADGLRADKLYELDEDGNSRAPFVRNIIMNEGSWGISHTRVPTESRPGHVAMIAGFYEDVSAVAKGWKENPVEFDSLLNETRYTWSWGSPDILAMFAKGIDTNGHAHRPSSREYSDNIKLVDKELKEIESTVKDFYGNDGKTAFIFTADHGMTDWGSHGAGHPLETCTPFIAWGAGIRLPQKVSAQKFDDSYLQEWKLENWKRQDINQGIIPVDMLNTSDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKSLSDTKQANILRKARYYIKQKKYDEAVSLCRQLIHLALRGLAYYHTYDRFFLAFNVVLGFVGWTSYASLLIIKSHCNLMRGVSTEAKNPSRLLPCAFGAVGVSVTFFLLIQACPWTYYVYCLLPLPIWYAVLREIPVIQGFVTLLSTFPPRRFLGYLLLFILGVEVLVLSFFYRYMLTAGLVALAAWPFITALWTRAKSISLSWIFFCLLLAVFPLMPVVGRKPDIFLVVGAGLLVLLLSLFVVTSVIKRKDSFINEELVLHLLQMLSVMFSMCVVYGTHHSLLKKQGLPLLNQIVSWTILASSFVMPLLSPPVLFDRLFSILVSSMSTYLLLSTGYEALFPLVLSCLMFVWIHMEQETLQHSVVSCKQKVSTIQFACNTDAAQCRDLCLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDPSSVYCFLTVFSPFKMGALIMWKILIPFVLVMCAFEAVQVTTQLSSKSLFLMVINISDIMALHFFFLIKDYGSWLDIGTSISHYVIVMSMTIFMVFLNCLAQMLTTRKLSLCGRPKSHVI", "length": 847, "header": "tr|A0AAA9SJN7-1|E1BM45_BOVIN Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Bos taurus OX=9913 GN=PIGN PE=3 SV=1 CANONICAL=E1BM45-1" }, "locus": { "chromosome": "24", "start_pos": 60593232, "end_pos": 60494406, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090850.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090850.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084112.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084112.1" } ] } }, { "isoform_ac": "A0AAA9SPR4-1", "url": "https://www.uniprot.org/uniprotkb/E1BM45/entry#A0AAA9SPR4-1", "sequence": { "sequence": "MLLYITLGLLVHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLMLFVADGLRADKLYELDEDGNSRAPFVRNIIMNEGSWGISHTRVPTESRPGHVAMIAGFYEDVSAVAKGWKENPVEFDSLLNETRYTWSWGSPDILAMFAKGDLRSHIFTESYDASSEDFGAHDVTKLDTWVFDHVKEFFHAARNNQSLFSKVNEDKIVFFLHLLGIDTNGHAHRPSSREYSDNIKLVDKELKEIESTVKDFYGNDGKTAFIFTADHGMTDWGSHGAGHPLETCTPFIAWGAGIRLPQKVSAQKFDDSYLQEWKLENWKRQDINQADVAPLMAALIGVPFPLNSVGIIPVDMLNTSDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKIPVIQGFVTLLSTFPPRRFLGYLLLFILGVEVLVLSFFYRYMLTAGLVALAAWPFITALWTRAKSISLSWIFFCLLLAVFPLMPVVGRKPDIFLVVGAGLLVLLLSLFVVTSVIKRKDSFINEELVLHLLQMLSVMFSMCVVYGTHHSLLKKQGLPLLNQIVSWTILASSFVMPLLSPPVLFDRLFSILVSSMSTYLLLSTGYEALFPLVLSCLMFVWIHMEQETLQHSVVSCKQKVSTIQFACNTDAAQCRDLCLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDPSSVYCFLTVFSPFKMGALIMWKILIPFVLVMCAFEAVQVTTQLSSKSLFLMVINISDIMALHFFFLIKDYGSWLDIGTSISHYVIVMSMTIFMVFLNCLAQMLTTRKLSLCGRPKSHVI", "length": 797, "header": "tr|A0AAA9SPR4-1|E1BM45_BOVIN Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Bos taurus OX=9913 GN=PIGN PE=3 SV=1 CANONICAL=E1BM45-1" }, "locus": { "chromosome": "24", "start_pos": 60593232, "end_pos": 60494406, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098513.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098513.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085987.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085987.1" } ] } }, { "isoform_ac": "E1BM45-1", "url": "https://www.uniprot.org/uniprotkb/E1BM45/entry#E1BM45-1", "sequence": { "sequence": "MLLYITLGLLVHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLMLFVADGLRADKLYELDEDGNSRAPFVRNIIMNEGSWGISHTRVPTESRPGHVAMIAGFYEDVSAVAKGWKENPVEFDSLLNETRYTWSWGSPDILAMFAKGDLRSHIFTESYDASSEDFGAHDVTKLDTWVFDHVKEFFHAARNNQSLFSKVNEDKIVFFLHLLGIDTNGHAHRPSSREYSDNIKLVDKELKEIESTVKDFYGNDGKTAFIFTADHGMTDWGSHGAGHPLETCTPFIAWGAGIRLPQKVSAQKFDDSYLQEWKLENWKRQDINQADVAPLMAALIGVPFPLNSVGIIPVDMLNTSDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKSLSDTKQANILRKARYYIKQKKYDEAVSLCRQLIHLALRGLAYYHTYDRFFLAFNVVLGFVGWTSYASLLIIKSHCNLMRGVSTEAKNPSRLLPCAFGAVGVSVTFFLLIQACPWTYYVYCLLPLPIWYAVLREIPVIQGFVTLLSTFPPRRFLGYLLLFILGVEVLVLSFFYRYMLTAGLVALAAWPFITALWTRAKSISLSWIFFCLLLAVFPLMPVVGRKPDIFLVVGAGLLVLLLSLFVVTSVIKRKDSFINEELVLHLLQMLSVMFSMCVVYGTHHSLLKKQGLPLLNQIVSWTILASSFVMPLLSPPVLFDRLFSILVSSMSTYLLLSTGYEALFPLVLSCLMFVWIHMEQETLQHSVVSCKQKVSTIQFACNTDAAQCRDLCLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDPSSVYCFLTVFSPFKMGALIMWKILIPFVLVMCAFEAVQVTTQLSSKSLFLMVINISDIMALHFFFLIKDYGSWLDIGTSISHYVIVMSMTIFMVFLNCLAQMLTTRKLSLCGRPKSHVI", "length": 931, "header": "tr|E1BM45-1|E1BM45_BOVIN Isoform 1 of GPI ethanolamine phosphate transferase 1 OS=Bos taurus OX=9913 GN=PIGN PE=3 SV=2 CANONICAL=E1BM45-1" }, "locus": { "chromosome": "24", "start_pos": 60593232, "end_pos": 60494406, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022160.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022160.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022160.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022160.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:525095", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525095", "resource": "KEGG Pathway" }, { "id": "R-BTA-162710", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-162710", "resource": "Reactome", "description": "Synthesis of glycosylphosphatidylinositol (GPI)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1I9LQ21-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLVGELGRSMRSDGILGVGGSDQSRATAVVVASRRRWLKRRETWLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKPLVHHSFSLSQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSSLSGDLSKKEHLSVQKKDSGKVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPAEIPDNNNLVVTSGAIIIVISLAAKWLDTHAEGNKFWQSITFHESRTQMCSMLYCIQIFLVGVSSVMVFLSTKHRTQNQELHSSHQFINWLVAGSSMVLPLFSANGILSRLSSIFLGFAPPFLLLSIGYEAVFYSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALTNLYTRSIRIKPLSTSPSLKTL", "length": 1001 }, "evidence": [ { "id": "E1BM45", "url": "https://omabrowser.org/oma/group/E1BM45/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A8C2M2G6-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "Pign", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLLFFALGLLVHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADALYGLDEDGNSSAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAQDATKLDTWVFDKVKDFFDAARNNQSLFSKVNEEKIVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEIVSVFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKFPEKVSAQQFDDKFLKEWKLENWKRRDVDQADIAPLMASLIGVPFPLNSVGTLPVDYLNNTGLFKAESMLTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALKGLSYYHTYDRFFLGISVASGFVGWTSYASLLILKSHSNFTRSSRKEVKKPHYLLLCSFVAIGVLVVCFLLIQVCPWTYYVYCLLPVPIWYAVLREYQVIQDLVASLLTFPPSHFVAHLLVFILGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQPWTQAKITYLSWALFSLLLAVFPLMPVVGRKPDLSLVMGAGLLVLLLALAIVTVLTKRKITLVKEELLVLLLQVLSTVLSMYVVYSTHHSLLEKEGLPLMNQIVSWTTLASSLVVPLLSSTILFQRLSSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIHMEQETLHQPGVSCKQKLTSIQFTCNTDIAQLRLLDLDDVRRAFFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLIVLVISDIMALHFFFLVKDSGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLQLCGKPKSHLL", "length": 931 }, "evidence": [ { "id": "E1BM45", "url": "https://omabrowser.org/oma/group/E1BM45/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0YKZ7-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "PIGN", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPAGLAAGGSECWRLRAGRSLAVCASTLLCSRPVEGSVFMETSHCPGLLSLLQCWALPWWPPVTMGVPVFILAGLLVHFVFLASIFDIYFSSPLVHGMTPQQTPLPPPAKRLVLFVADGLRADSLFELNSNNTPQAPYLRAILENNGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESKHTWSWGSPDILPMFAKGATGDHVYTFCYTAESEDFGAQDAAELDTWVFDHVKSFFNSSRSNQTLFSALNEEKVVLFLHLLGIDTNGHAHRPYSKEYKENIRKVDEGVEEIVSMLESFYGNDGKTAYILTSDHGMTDWGSHGAGHPSETLTPLIAWGAGVNYPQEVTSQLFEDNFLKEWKLENLKRMDVNQADIAPLMASLIGVPFPLNSVGTLPLEYLNNSDHFKAESMFTNAVQVLEQFKVKMSQKKRTTLSFLFTPFKPLSDSEQINFLKKARLYIQQQKYSEAVSLCKTLINLALEGLSYYHTYDRLFLGLSIAVSFVGWTTYVILVIIKTHTNLIKAAQINNKESTGPLYSFMFAGMIIAFFLLIQASPWTYYVYCLLPVPIWYAVVRELHVIQDLAANLWSLPVGHSVGFLLICILGIELLVFSFFYRSTLTVGLLVFAGWPVITQMWVQAKRTTLIWTLLCVFLAVFPLMPVVGREPNIPLVIVAGLTTLLISCFSLASFSRSENKYRGKEDLKVYFYQMFSIALSTYVVSSTHNSLKNKQGLPVFNQIVSWMTLASSSALPLLSPTLLFQRLFSILLSLMATYLLLSTGYEALFPLVLSGLMLVWIQMEQEALQHYGLSLRSKLAVFNFAYATDITQFRQLHLDDIRRSFFFVFFIVTAFFGTGNIASVNSFDPASVYCFLTVFSPFMMGGLLLLKVVIPFVLVSCAFEAVQVTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVLVMSLTIFMMLMNGLAQLLTTKRLELSRRTKHHSM", "length": 997 }, "evidence": [ { "id": "E1BM45", "url": "https://omabrowser.org/oma/group/E1BM45/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LNZ1-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "Pign", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLFFALGLLVHFVFFASIFDIYFTSPLVHGMTPQVTPLPPPAKRLVLFVADGLRADALYELDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFSIVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYEDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQYEDEFLKEWRLENWKRQDINQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDDVVSLCEELIDLALRGLSYYHTYDRLFLGISVAVGFVGWTSYASLLIIKSHSDIPRGTRREGKKPHHLLPCSFIVAGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLKEREVIQALVESLLAFPLSRFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTRAKITCLSWAFFSLLLAVFPLMPVVGRKPDLSLVMGAGLLVLLLSLAVLATLVKRKLNLVKDELLVLLLQVLSTVLSMYVVYSTHHSLLKKEGLPLLNQIVSWATLASSLVVPLLSPTALWQRLTSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIHVEQETLQQSGVSCKQKLASIQFTYNTDITQFRQLCLDDIRRAFFLVFFLLTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLVISDIMALHFFFLVKDSGSWLDIGTSEKWIGKVGQENVAKASLQ", "length": 909 }, "evidence": [ { "id": "E1BM45", "url": "https://omabrowser.org/oma/group/E1BM45/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1Z838-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "PIG-N", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWIAYALVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADSFFEENCRYVPNLRKIFLREGVVGVSRTRVPTETRPGHITLIAGLYEDPSAVLRGWKSNPIDFDTVFNRSSQTYAWGANDVLNVFSHVSNGGEINLRFYNHDLDFSPGYDAYEEDEWVFKRVKLLLQQKREALQRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRTLEKTEKGVYAIYQEFERVFPDKRTAYLLTADHGMTDSGAHGSGSPHETDTPFMLWGAGASRAVPKPGGRTFMPNNEGPAMPLHELEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNVSKEYEAMAAHVNALQLLEQYVALQKQHKKGFFADILLEYDVLNAEAIKRYKDTIVQLQKKREYSLCIDKSQVIMSQALEGIDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSRNRASKVELVLERSNKIVRVSIVSSVIVLIICLLSQGTPLDISFYLLLPYFVWLKALQPWNINFSSSPASAYSVPALQTSMWQLVLLIACAELMVFTFFERRLIALCFCVFACYNSWENFQWKSRDFFSWLALVLILSCFPLLPLSVGYQNGYLLGAGVIVIFTNSFWNSKSRLCYRNHTKYSNALILLQTILCAYLHSNGINIPIPLKLASWLYLVYAFASILLSKESRLDLRLAQIGFNLGSLYATLCTSYEAVFVQLLTIELNISLRAQSARAERSVLRLAFTLLLYTFFSLFGSGNIASISSFDPNIARCYLSHFAPFVIMGLVLLKLLVPVVLIMSVIYANSEFVRQHEEQIFICLLLICDVMGLNFLFLVRNQGSWLDIGTSISHFVIMEVTTLVMLVIFYTAKQLLRVIPWEEIDFKMLPLRLIHWDVISAKHH", "length": 894 }, "evidence": [ { "id": "E1BM45", "url": "https://omabrowser.org/oma/group/E1BM45/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "E7EXW2-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "pign", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKMVTFFVVGLIVHVVFFLCIFDIYFTSPLVHGMTPQRVSLPPPAKRLVLFVADGLRADSLFKPDDSGTSRAPYLRSVIEEGGTWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESRYTWCWGSPDILPMFAKGATGDHVYTHTYPPEREDFASTDASRLDTWVFDEVKDFLTAAKSNETLLKKLHEEQNVFFLHLLGIDTNGHAHRPMSKECLENIGLVDAGVADIVTVMDDFYGHDGKTAYVFTSDHGMTNWGSHGAGHPSETLTPLVVWGAGVQKAQWETSQKYEDNYLKEWGLESYRRVDVNQADIAPLMSSLIGIPFPLNSVGVLPLSYLNNSQHFKAESMYANAIQILEQFRVKLAQKKETTISFLFTPYQPLTDSKQVDFIRQARDLIQKGRFDEAIVYCKDLIAQAMEGLSYYHTYDRLFLGSSVVLGFIGWTSYVVLYILKTHASLRKPPTNTSMVTERLLGWGFLCVGLLMALFLLVQSSPWSYYIYSLMPVAVWYAVLKEFKTLVGLVRSIPSLPLTKCFGYFVLVAFGIELLVMSFFYRAMLSLGLVVLALWPVVSGFYTKAKFKSLSWTLSCLSLAVFPLLPVVGREPNINYVISAGGLILFNSSSFLWSSWRDSPLMRRDRQLFIFQMVQVALCAYTLTSTHSSLQLKQGLPIFNQLVSWSTLVSSFLIPLLSSTRLFHRLLSILMSLTCVYLLLSTGHEALFPLMLSWLMLAWIHIEQEAMSRQGSSNRNELSCIDFAENIDITKVRQLRLDDIRKSYFFVFFIIIAFFGCGNIASINSFDPASVYCFLTVFNPFIMGGLLMWKVLIPFVIVMCTFESIQVSTQLSSRSLFLIVLVISDLMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLMLLSVMTHILTSKKILLGRSRKMHFR", "length": 932 }, "evidence": [ { "id": "E1BM45", "url": "https://omabrowser.org/oma/group/E1BM45/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O95427-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "PIGN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPARRLVLFVADGLRADALYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLRLCGKPKSHFM", "length": 931 }, "evidence": [ { "id": "E1BM45", "url": "https://omabrowser.org/oma/group/E1BM45/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P36051-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "MCD4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFYPFICGVRELSVNILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEVLGHVLLKNVIIQDKTKKTQ", "length": 919 }, "evidence": [ { "id": "E1BM45", "url": "https://omabrowser.org/oma/group/E1BM45/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54WY9-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "pigN", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYHIISSNINNINNKSNKPNDNKNDKTKFNSKILVIVLIGIIFHAVFTLSIFDIYFRSPLVHGMTPHPINLPAPAKRLVLFVADGLRADKFFEIDENTGKSRSPFLRNIIENKGTWGISHTRVPTETRPGHVALIAGFYEDVSAVTKGWKANPVEFDHLFNETTYSFGYGSPDVLPMFSEGVPHMQSESYPEEAEDFASDASKLDTWVFDKVQQLLLNASTNDQELNRKLRSDKVSIFLHLLGLDTNGHAYRPNSKEYFDNIALVDRGIEKIVKLIEDFYGNDGKTAFVFTADHGMSNRGSHGDGERANTETPLVVWGSGVRGPLSSDLQMERIASLRGKAKEMLPVNVETPTNWKLSSLFRSDVSQADIAPLMTSLLGVPSPLNSVGVLPTEILSEDTPQYTTAALRANTLQIWEMYKIKSSSKQQSTLIFFSPFTKLSDADRMFERIEQHISLSQWEDAQILCHQMIDLCLMGLNYFQTYDRPFLMTVITMGYFGWIITLSLYVLNNYTSIGIENCNQQKLSTQMKRFKTLSNYLIFIESIALVGFLLATDAPLLYYLYCVFLVLFWAKTIPSNIVPLYIFICDSFSQVSSTRGHFINTNNSANLSIIKNFIILSVSAISVMELLVVSYFHRGVLSLLYQILGVVSVFFFYNRSGAGKTSTLLKSLWLISCLLMSIFPSLPIDYGSDTKLVCFGGILISILGVLTSLFKFRNNSKQQQQSSSSSQQKLQKSKKNQIINSILIISILLSSFIVYTTDSSLEKKIGLPFINQLLSWILLVSGVLILAIYRGKGFYDHWTFLCLSLSIPFLLLSISYEVLFFGNLILNLTLWMYFELKVDNDHTIPKLVSITPNSEPSTSLSFSKSASKSNLMNITQHDIRRAIFYIFFCYVGFFGVGNIASISSFEISSTYRFTTIFRPFLMGALLLVKIFIPLLLVAISFSLLNNNLNVPRPGSFLIVIALTDIMSINFFFLVKDTGSWLEIGVSISHYAISNAFIILQLLLFAVSALLVPTTLKYINNNSNNNNNTIKSK", "length": 1032 }, "evidence": [ { "id": "E1BM45", "url": "https://omabrowser.org/oma/group/E1BM45/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9R1S3-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "Pign", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVIIHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIVSWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLIISDIMALHFFFLVKDSGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLQLCGKPKSHLM", "length": 931 }, "evidence": [ { "id": "E1BM45", "url": "https://omabrowser.org/oma/group/E1BM45/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mannose-ethanolamine phosphotransferase activity", "id": "GO:0051377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051377", "evidence": [ { "database": "UniProtKB", "id": "E1BM45", "url": "https://www.uniprot.org/uniprotkb/E1BM45" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BM45", "url": "https://www.uniprot.org/uniprotkb/E1BM45" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BM45", "url": "https://www.uniprot.org/uniprotkb/E1BM45" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BM45", "url": "https://www.uniprot.org/uniprotkb/E1BM45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "E1BM45", "url": "https://www.uniprot.org/uniprotkb/E1BM45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 866, "end_pos": 868, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-162798", "name": "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-8855659" ], "output_participant_list": [], "enzyme_list": [ "E1BM45-1" ], "evidence": [ { "id": "R-BTA-162798", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-162798" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8855659", "participant_name": "mannose (a1-4) glucosaminyl-acyl-PI [lumenal side of endoplasmic reticulum membrane]", "crossref": [ { "id": "53056", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BM45", "gene_name": "PIGN", "activity": [ { "ec_number": "2.-.-.-", "activity": "", "evidence": [ { "id": "E1BM45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM45" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM45-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 931, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM45-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM45" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM45" }, { "id": "PF04987", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04987" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GPI ethanolamine phosphate transferase 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 430, "end_pos": 884, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 350, "end_pos": 352 }, { "start_pos": 866, "end_pos": 868 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMD8-1", "uniprot_ac": "E1BMD8", "uniprot_id": "E1BMD8_BOVIN", "mass": { "chemical_mass": 49660.0, "monoisotopic_mass": 49660.0 }, "refseq": { "ac": "NP_001193667", "name": "sorting nexin-30", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193667" }, "gene_names": [ { "name": "SNX30", "type": "recommended", "evidence": [ { "id": "E1BMD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ] }, { "name": "SNX30", "type": "synonym", "evidence": [ { "id": "NP_001193667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193667" } ] } ], "protein_names": [ { "name": "Sorting nexin-30", "type": "recommended", "evidence": [ { "id": "E1BMD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD8/entry#names_and_taxonomy" } ] }, { "name": "sorting nexin-30", "type": "synonym", "evidence": [ { "id": "NP_001193667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193667" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SNX30", "url": "https://www.uniprot.org/uniprotkb/E1BMD8", "locus": { "chromosome": "8", "start_pos": 102114092, "end_pos": 102004377, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000044070", "url": "https://www.ensembl.org/id/ENSBTAG00000044070" } ] } } ], "crossref": [ { "id": "E1BMD8", "url": "https://alphafold.ebi.ac.uk/entry/E1BMD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000044070", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044070", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06860", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06860", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07667", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07667", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "517400", "url": "https://www.ncbi.nlm.nih.gov/gene/517400", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:517400", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517400", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSLHRFI", "url": "https://omabrowser.org/oma/group/WSLHRFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMD8", "url": "https://www.orthodb.org/?gene=E1BMD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45949", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45949", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45949:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45949:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193667", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193667", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SEU1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SEU1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXH4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXH4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLR7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLR7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3L1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3L1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMD8-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGPPKALQSTGPQSLRDMPHPLAGSSSEEAVGGDSTPSPDLLTARSFGDKDLILPNGGTPAGTASPASSSSLLNRLQLDDDMDGETRDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAHKKQGMALLTRVGESVKHVAGGYKLRNRPLEFAAIGEYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYETKLEAVALKKEERPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESIIPLLQEKQEAK", "length": 437, "header": "tr|E1BMD8-1|E1BMD8_BOVIN Isoform 1 of Sorting nexin-30 OS=Bos taurus OX=9913 GN=SNX30 PE=3 SV=3 CANONICAL=E1BMD8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SEU1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD8/entry#A0AAA9SEU1-1", "sequence": { "sequence": "MSGGPPKALQSTGPQSLRDMPHPLAGSSSEEAVGGDSTPSPDLLTARSFGDKDLILPNGGTPAGTASPASSSSLLNRLQLDDDMDGETRDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAHKKQGMALLTRVGESVKHVAGGYKLRNRPLEFAAIGEYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYETKLEAVALKKEERPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESIIPLLQEKQEAKRYPFIGKNQDMQSNGKKYQLFYSSFLILNLPSPTSYKMALI", "length": 478, "header": "tr|A0AAA9SEU1-1|E1BMD8_BOVIN Computationally mapped isoform of Sorting nexin-30 OS=Bos taurus OX=9913 GN=SNX30 PE=3 SV=1 CANONICAL=E1BMD8-1" }, "locus": { "chromosome": "8", "start_pos": 102114021, "end_pos": 102004576, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132033.2", "url": "https://www.ensembl.org/id/ENSBTAT00000132033.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080934.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080934.1" } ] } }, { "isoform_ac": "A0AAA9TXH4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD8/entry#A0AAA9TXH4-1", "sequence": { "sequence": "MSGGPPKALQSTGPQSLRDMPHPLAGSSSEEAVGGDSTPSPDLLTARSFGDKDLILPNGGTPAGTASPASSSSLLNRLQLDDDMDGETRDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAHKKQGMALLTRVGESVKHVAGGYKLRNRPLEFAAIGEYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKHVVQLNVSAAVAEEWPPPTGPHALLENRRLETQRLEASASVAKKVLVTLGLPLVVLLKEEKETFG", "length": 403, "header": "tr|A0AAA9TXH4-1|E1BMD8_BOVIN Computationally mapped isoform of Sorting nexin-30 OS=Bos taurus OX=9913 GN=SNX30 PE=3 SV=1 CANONICAL=E1BMD8-1" }, "locus": { "chromosome": "8", "start_pos": 102094026, "end_pos": 102004576, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102240.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102240.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103036.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103036.1" } ] } }, { "isoform_ac": "A0ABI0NLR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD8/entry#A0ABI0NLR7-1", "sequence": { "sequence": "MLSNGSSVKDLILPNGGTPAGTASPASSSSLLNRLQLDDDMDGETRDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAHKKQGMALLTRVGESVKHVAGGYKLRNRPLEFAAIGEYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYETKLEAVALKKEERPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESIIPLLQEKQEAK", "length": 394, "header": "tr|A0ABI0NLR7-1|A0ABI0NLR7_BOVIN Computationally mapped isoform of Sorting nexin-30 OS=Bos taurus OX=9913 GN=SNX30 PE=3 SV=1 CANONICAL=E1BMD8-1" }, "locus": { "chromosome": "8", "start_pos": 102107749, "end_pos": 102003634, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152660.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152660.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106114.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106114.1" } ] } }, { "isoform_ac": "A0ABI0P3L1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD8/entry#A0ABI0P3L1-1", "sequence": { "sequence": "MGLSCAMLGECIDDQMTLPSSHSRSRKGDREVQDLILPNGGTPAGTASPASSSSLLNRLQLDDDMDGETRDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAHKKQGMALLTRVGESVKHVAGGYKLRNRPLEFAAIGEYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYETKLEAVALKKEERPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESIIPLLQEKQEAK", "length": 418, "header": "tr|A0ABI0P3L1-1|A0ABI0P3L1_BOVIN Computationally mapped isoform of Sorting nexin-30 OS=Bos taurus OX=9913 GN=SNX30 PE=3 SV=1 CANONICAL=E1BMD8-1" }, "locus": { "chromosome": "8", "start_pos": 102107749, "end_pos": 102018194, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139681.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139681.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105430.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105430.1" } ] } }, { "isoform_ac": "E1BMD8-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD8/entry#E1BMD8-1", "sequence": { "sequence": "MSGGPPKALQSTGPQSLRDMPHPLAGSSSEEAVGGDSTPSPDLLTARSFGDKDLILPNGGTPAGTASPASSSSLLNRLQLDDDMDGETRDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAHKKQGMALLTRVGESVKHVAGGYKLRNRPLEFAAIGEYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYETKLEAVALKKEERPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESIIPLLQEKQEAK", "length": 437, "header": "tr|E1BMD8-1|E1BMD8_BOVIN Isoform 1 of Sorting nexin-30 OS=Bos taurus OX=9913 GN=SNX30 PE=3 SV=3 CANONICAL=E1BMD8-1" }, "locus": { "chromosome": "8", "start_pos": 102107749, "end_pos": 102004576, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061575.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061575.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053240.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053240.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:517400", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517400", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A447-1", "protein_name": "Sorting nexin-30", "gene_name": "SNX30", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRPPKALPSTGPHSLRDMPHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGGTPAGTASPASSSSLLNRLQLDDDIDGETRDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNVYKKQGMALLSRVGESVKHVTGGYKLRSRPLEFAAIGEYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEERPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESIIPLLQEKQEAK", "length": 437 }, "evidence": [ { "id": "E1BMD8", "url": "https://omabrowser.org/oma/group/E1BMD8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A060-1", "protein_name": "Sorting nexin-30", "gene_name": "Snx30", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGPPKALPSTGPQSLRDMPHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGGTPAGTSSPASSSSLLNRLQLDDDIDGETRDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAYKKQGIALLTRVGESVKHVTGGYKLRSRPLEFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDITEEFLPVLREYILYSDSMKGVLKKRDQVHAEYEAKLEAVALRKEDRPKVPADVEKCQDRMECFNADLKADMERWQGNKRNDFRQLLVGLADKNIQYYEKEMGPILVHASSHN", "length": 431 }, "evidence": [ { "id": "E1BMD8", "url": "https://omabrowser.org/oma/group/E1BMD8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1ND98-1", "protein_name": "Sorting nexin-30", "gene_name": "SNX30", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGGAAGIPKPLPSSGPKSLREMPHPLATSSSEEMGPALTPSPDLLLPRSIADKDLSLPNGTPVDTSSPASSSSLLNRLQLDDDLDGETKDLFVTVDDPKKHVCTMETYITYRVTTKTTRAEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAYKKQGMALLSKMGESVKYVTGGYKLRSRPLEFAAIGEYLDTFSLKLGTIDRIAQRIIKEQLEYLVELREYGPIYSTWGGLEVELSEPLEGVSACIGNCCTALEELSEDMTDDFLPVLREYILYSESMKNVLKKRDQVQAEYEAKLEAVALKKEDRPKVPTDVEKCQDRVECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLTAWESIIPLLQDKPETK", "length": 438 }, "evidence": [ { "id": "E1BMD8", "url": "https://omabrowser.org/oma/group/E1BMD8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5VWJ9-1", "protein_name": "Sorting nexin-30", "gene_name": "SNX30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGPPKALPSTGPHSLRDMPHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGGTPAGTSSPASSSSLLNRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAKDLNAYKKQGIALLTRMGESVKHVTGGYKLRTRPLEFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEDRPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESIIPLLQEKQEAK", "length": 437 }, "evidence": [ { "id": "E1BMD8", "url": "https://omabrowser.org/oma/group/E1BMD8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86IF6-1", "protein_name": "Phox domain-containing protein", "gene_name": "vps5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDYNSNLLFGTQVTYEDNGENTFVGFSNEPIESSNPFLAPPQQQEQQEQPSYPQVQQQYSKERIPASQPPSYNPPQPTQQQQQQTNNNGTTVQQKQRTSQNYQQPPPQQQQQVSNNSNFQSNFKPTFTTPVNQFISNSRTSMDITVNFPDMVGEGMGAYAIYKIVTKSALNENPDYKKEVSVNRRYSDFLWLRNALKETRKGCIIPQLPEKAVLNNRNKDFLEQRRRDLEKFLNRVVESNSLAQSNEILTFLEGSDEQLNAAKQSRPDQSNMESSTMSPPPSQEGGKMGKISSFFGNSISTLTQGVHSVKEIDGWFGDKKSYILQLDSTLHRLEDTINNVIRKRRELAAAMGELTSAGLSFSSCEIPVRQDIANGYQRLTEVENNIRQGMEDLSNNEQGYFEEGIRDYLRAISSVKELLNDRLDALMSMQNNERNVAAKKEKAAKTTGAKAANMQKEVDDAVRKLTEATTEYEKISASARLELTKFDEKRAYEMKRILNYVIRLNLDHFLKSSDCWRELLTEQHSNGDPNFDSKNKASWGSTSI", "length": 545 }, "evidence": [ { "id": "E1BMD8", "url": "https://omabrowser.org/oma/group/E1BMD8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8CE50-1", "protein_name": "Sorting nexin-30", "gene_name": "Snx30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGGPPKALPSTGPQSLRDMPHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGGTPAGTASPASSSSLLNRLQLDDDIDGEARDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAYKKQGIALLSRVGESVKHVTGGYKLRSRPLEFAAISDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDITEEFLPVLREYVLYSDSMKGVLKKRDQVQAEYEAKLEAVALRKEERPKVPADVEKCQDRMECFNADLKADMERWQSNKRHDFRQLLVGLADKNIQYYEKCLMAWESIIPLLQEKQETK", "length": 437 }, "evidence": [ { "id": "E1BMD8", "url": "https://omabrowser.org/oma/group/E1BMD8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ], "pmid": "" }, { "name": "positive regulation of autophagosome assembly", "id": "GO:2000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000786", "evidence": [ { "database": "UniProtKB", "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "E1BMD8", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMD8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 437, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMD8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMD8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD8" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 210, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 38, 61 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 307, "end_pos": 309 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BN58-1", "uniprot_ac": "E1BN58", "uniprot_id": "E1BN58_BOVIN", "mass": { "chemical_mass": 122390.0, "monoisotopic_mass": 122390.0 }, "refseq": {}, "gene_names": [ { "name": "OTUD4", "type": "recommended", "evidence": [ { "id": "E1BN58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ] } ], "protein_names": [ { "name": "OTU domain-containing protein 4", "type": "recommended", "evidence": [ { "id": "E1BN58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN58/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "E1BN58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN58/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Deubiquitinase which hydrolyzes the isopeptide bond between the ubiquitin C-terminus and the lysine epsilon-amino group of the target protein. May negatively regulate inflammatory and pathogen recognition signaling in innate immune response. Upon phosphorylation at Ser-202 and Ser-204 residues, via IL-1 receptor and Toll-like receptor signaling pathway, specifically deubiquitinates 'Lys-63'-polyubiquitinated MYD88 adapter protein triggering down-regulation of NF-kappa-B-dependent transcription of inflammatory mediators. Independently of the catalytic activity, acts as a scaffold for alternative deubiquitinases to assemble specific deubiquitinase-substrate complexes. Associates with USP7 and USP9X deubiquitinases to stabilize alkylation repair enzyme ALKBH3, thereby promoting the repair of alkylated DNA lesions.", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58#function" }, { "database": "UniProtKB", "id": "ARBA00058854", "url": "https://www.uniprot.org/uniprotkb/ARBA00058854#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OTUD4", "url": "https://www.uniprot.org/uniprotkb/E1BN58", "locus": { "chromosome": "17", "start_pos": 13152070, "end_pos": 13109445, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019857", "url": "https://www.ensembl.org/id/ENSBTAG00000019857" } ] } } ], "crossref": [ { "id": "E1BN58", "url": "https://alphafold.ebi.ac.uk/entry/E1BN58", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019857", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019857", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22794", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22794", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "528907", "url": "https://www.ncbi.nlm.nih.gov/gene/528907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12419:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12419:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02338", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02338", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SNN5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNN5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TER2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TER2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TER2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TER2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN58-1", "url": "https://www.uniprot.org/uniprotkb/E1BN58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAVGVPDGGDRGGAAPREDATPMDAYLRTLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIHYLRENREKFEEFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYQKPNVSPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKILMGLDSSEVADEDNSEISDSEDDSCKSKPTTINDVNGFKTLSSDQHPKSNGNSPSLPLSRKVLKSLSPAVYRNVEYEIWLKSKQAQQKHDYSIAAGLQYEVGDKCQVRLDHDGKFSNADFQGVHAENGPVLVAELGKKYSPKNLKPPASESWNTVSGKKMKKPPSGQNFHSDMDYRGPKNSSKPIKAPSALPPRLQHPSGARQHASSGHSAAPQSQKTSSEHKNLSRTPSQIIRKPDRERAEDFDATTREPNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVSQSASQSSNPGVQRKSSHGSDRKGSRRRMDTEERKDKDSVHGHISLDKKPEPGTLENIGNDKCARISSPSKSKKLECPPPTEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAQIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIAPPYSLCHTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPMYPQNPWFQEPPSAQNESDCTCPDAHFPMEPEGSVNGQMPQAEMGPPAFSSPLVMPPSQVSDSHGQLSYPADLESENAGQLLHADYEESLSSKNMFPQPSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLPLENLDLSKECASVSAAEEFPEAGGEDPHAPPEAGASKSDGRAERSSQTPKAEPAAAPGPPAAEGEAHVPAQLLNREREAGPAGLEPKRTIPSLKEKPEKGKEPKTAADVVSGANSVDSRVQRPKEESSEDENEVSHILRSGRSKQFYNQTFGGRKYKSDWGFSGRGGYPHARGEESWKGQPSRSRDEGYQYHRNARGRPYRGDRRRSGMGDGHRGQHT", "length": 1109, "header": "tr|E1BN58-1|E1BN58_BOVIN Isoform 1 of OTU domain-containing protein 4 OS=Bos taurus OX=9913 GN=OTUD4 PE=4 SV=4 CANONICAL=E1BN58-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SNN5-1", "url": "https://www.uniprot.org/uniprotkb/E1BN58/entry#A0AAA9SNN5-1", "sequence": { "sequence": "MMLQLLLFRHFSHHLALCDPVDWCWPARCVTPRTLPSPRWAGLLQMLQEWVGQVEISALSLMYRKDFIIYQKPNVSPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKILMGLDSSEVADEDNSEISDSEDDSCKSKPTTINDVNGFKTLSSDQHPKSNGNSPSLPLSRKVLKSLSPAVYRNVEYEIWLKSKQAQQKHDYSIAAGLQYEVGDKCQVRLDHDGKFSNADFQGVHAENGPVLVAELGKKYSPKNLKPPASESWNTVSGKKMKKPPSGQNFHSDMDYRGPKNSSKPIKAPSALPPRLQHPSGARQHASSGHSAAPQSQKTSSEHKNLSRTPSQIIRKPDRERAEDFDATTREPNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVSQSASQSSNPGVQRKSSHGSDRKGSRRRMDTEERKDKDSVHGHISLDKKPEPGTLENIGNDKCARISSPSKSKKLECPPPTEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAQIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIAPPYSLCHTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPMYPQNPWFQEPPSAQNESDCTCPDAHFPMEPEGSVNGQMPQAEMGPPAFSSPLVMPPSQVSDSHGQLSYPADLESENAGQLLHADYEESLSSKNMFPQPSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLPLENLDLSKECASVSAAEEFPEAGGEDPHAPPEAGASKSDGRAERSSQTPKAEPAAAPGPPAAEGEAHVPAQLLNREREAGPAGLEPKRTIPSLKEKPEKGKEPKTAADVVSGANSVDSRVQRPKEESSEDENEVSHILRSGRSKQFYNQTFGGRKYKSDWGFSGRGGYPHARGEESWKGQPSRSRDEGYQYHRNARGRPYRGDRRRSGMGDGHRGQHT", "length": 1059, "header": "tr|A0AAA9SNN5-1|E1BN58_BOVIN Computationally mapped isoform of OTU domain-containing protein 4 OS=Bos taurus OX=9913 GN=OTUD4 PE=4 SV=1 CANONICAL=E1BN58-1" }, "locus": { "chromosome": "17", "start_pos": 13148291, "end_pos": 13117687, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128921.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128921.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086961.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086961.1" } ] } }, { "isoform_ac": "A0AAA9TER2-1", "url": "https://www.uniprot.org/uniprotkb/E1BN58/entry#A0AAA9TER2-1", "sequence": { "sequence": "MQCIPHRMEQLGFMISADGFREGSPLYQKEWVGQVEISALSLMYRKDFIIYQKPNVSPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKILMGLDSSEVADEDNSEISDSEDDSCKSKPTTINDVNGFKTLSSDQHPKSNGNSPSLPLSRKVLKSLSPAVYRNVEYEIWLKSKQAQQKHDYSIAAGLQYEVGDKCQVRLDHDGKFSNADFQGVHAENGPVLVAELGKKYSPKNLKPPASESWNTVSGKKMKKPPSGQNFHSDMDYRGPKNSSKPIKAPSALPPRLQHPSGARQHASSGHSAAPQSQKTSSEHKNLSRTPSQIIRKPDRERAEDFDATTREPNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVSQSASQSSNPGVQRKSSHGSDRKGSRRRMDTEERKDKDSVHGHISLDKKPEPGTLENIGNDKCARISSPSKSKKLECPPPTEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAQIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIAPPYSLCHTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPMYPQNPWFQEPPSAQNESDCTCPDAHFPMEPEGSVNGQMPQAEMGPPAFSSPLVMPPSQVSDSHGQLSYPADLESENAGQLLHADYEESLSSKNMFPQPSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLPLENLDLSKECASVSAAEEFPEAGGEDPHAPPEAGASKSDGRAERSSQTPKAEPAAAPGPPAAEGEAHVPAQLLNREREAGPAGLEPKRTIPSLKEKPEKGKEPKTAADVVSGANSVDSRVQRPKEESSEDENEVSHILRSGRSKQFYNQTFGGRKYKSDWGFSGRGGYPHARGEESWKGQPSRSRDEGYQYHRNARGRPYRGDRRRSGMGDGHRGQHT", "length": 1040, "header": "tr|A0AAA9TER2-1|E1BN58_BOVIN Computationally mapped isoform of OTU domain-containing protein 4 OS=Bos taurus OX=9913 GN=OTUD4 PE=4 SV=1 CANONICAL=E1BN58-1" }, "locus": { "chromosome": "17", "start_pos": 13148291, "end_pos": 13119839, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122136.2", "url": "https://www.ensembl.org/id/ENSBTAT00000122136.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096595.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096595.1" } ] } }, { "isoform_ac": "E1BN58-1", "url": "https://www.uniprot.org/uniprotkb/E1BN58/entry#E1BN58-1", "sequence": { "sequence": "MEAAVGVPDGGDRGGAAPREDATPMDAYLRTLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIHYLRENREKFEEFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYQKPNVSPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKILMGLDSSEVADEDNSEISDSEDDSCKSKPTTINDVNGFKTLSSDQHPKSNGNSPSLPLSRKVLKSLSPAVYRNVEYEIWLKSKQAQQKHDYSIAAGLQYEVGDKCQVRLDHDGKFSNADFQGVHAENGPVLVAELGKKYSPKNLKPPASESWNTVSGKKMKKPPSGQNFHSDMDYRGPKNSSKPIKAPSALPPRLQHPSGARQHASSGHSAAPQSQKTSSEHKNLSRTPSQIIRKPDRERAEDFDATTREPNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVSQSASQSSNPGVQRKSSHGSDRKGSRRRMDTEERKDKDSVHGHISLDKKPEPGTLENIGNDKCARISSPSKSKKLECPPPTEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAQIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIAPPYSLCHTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPMYPQNPWFQEPPSAQNESDCTCPDAHFPMEPEGSVNGQMPQAEMGPPAFSSPLVMPPSQVSDSHGQLSYPADLESENAGQLLHADYEESLSSKNMFPQPSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLPLENLDLSKECASVSAAEEFPEAGGEDPHAPPEAGASKSDGRAERSSQTPKAEPAAAPGPPAAEGEAHVPAQLLNREREAGPAGLEPKRTIPSLKEKPEKGKEPKTAADVVSGANSVDSRVQRPKEESSEDENEVSHILRSGRSKQFYNQTFGGRKYKSDWGFSGRGGYPHARGEESWKGQPSRSRDEGYQYHRNARGRPYRGDRRRSGMGDGHRGQHT", "length": 1109, "header": "tr|E1BN58-1|E1BN58_BOVIN Isoform 1 of OTU domain-containing protein 4 OS=Bos taurus OX=9913 GN=OTUD4 PE=4 SV=4 CANONICAL=E1BN58-1" }, "locus": { "chromosome": "17", "start_pos": 13148291, "end_pos": 13109644, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026452.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026452.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026452.7", "url": "https://www.ensembl.org/id/ENSBTAP00000026452.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1-mediated signaling pathway", "id": "GO:2000660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000660", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "DNA alkylation repair", "id": "GO:0006307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006307", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "negative regulation of toll-like receptor signaling pathway", "id": "GO:0034122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034122", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "regulation of protein K48-linked deubiquitination", "id": "GO:1903093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903093", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "protein K11-linked deubiquitination", "id": "GO:0035871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035871", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "cysteine-type peptidase activity", "id": "GO:0008234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008234", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BN58", "url": "https://www.uniprot.org/uniprotkb/E1BN58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1039, "end_pos": 1041, "annotation": "n_glycosylation_sequon" }, { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 755, "end_pos": 757, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN58-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1109, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN58-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN58" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN58" }, { "id": "PS50802", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50802" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OTU", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 155, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1039, "end_pos": 1041 }, { "start_pos": 124, "end_pos": 126 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 408, "end_pos": 410 }, { "start_pos": 755, "end_pos": 757 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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{ "uniprot_canonical_ac": "E1BLS3-1", "uniprot_ac": "E1BLS3", "uniprot_id": "E1BLS3_BOVIN", "mass": { "chemical_mass": 123565.0, "monoisotopic_mass": 123565.0 }, "refseq": {}, "gene_names": [ { "name": "SEC31B", "type": "recommended", "evidence": [ { "id": "E1BLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ] } ], "protein_names": [ { "name": "Protein transport protein Sec31B", "type": "recommended", "evidence": [ { "id": "E1BLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLS3/entry#names_and_taxonomy" } ] }, { "name": "SEC31-like protein 2", "type": "synonym", "evidence": [ { "id": "E1BLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLS3/entry#names_and_taxonomy" } ] }, { "name": "SEC31-related protein B", "type": "synonym", "evidence": [ { "id": "E1BLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLS3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum.", "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3#function" }, { "database": "UniProtKB", "id": "ARBA00055331", "url": "https://www.uniprot.org/uniprotkb/ARBA00055331#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SEC31B", "url": "https://www.uniprot.org/uniprotkb/E1BLS3", "locus": { "chromosome": "26", "start_pos": 21378300, "end_pos": 21411777, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000090", "url": "https://www.ensembl.org/id/ENSBTAG00000000090" } ] } } ], "crossref": [ { "id": "E1BLS3", "url": "https://alphafold.ebi.ac.uk/entry/E1BLS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000090", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000090", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507880", "url": "https://www.ncbi.nlm.nih.gov/gene/507880", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1L0", "url": "https://www.orthodb.org/?gene=A0A3Q1M1L0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BLS3", "url": "https://www.orthodb.org/?gene=E1BLS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13923", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13923", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13923:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13923:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LL46", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LL46-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1L0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1L0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLS3-1", "url": "https://www.uniprot.org/uniprotkb/E1BLS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLKELERQAVQVWSPASQYPVYLATGTSAQQLDASFSTNGTLEIFEVDFRDPSLDLKRKGVLSASSRFHKLIWGSFGSGLLEASGVIAGGGDNGMLTLYNVTHVLSSGKEPVIAQRQKHSGAVRALDFNPFQGNLLASGANDSEIFIWDLNNLSVPMTPGSKSQPLEDIKALSWNRQVQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLSSAKDSQILCWNLGSSEVVYKLPMLSSWCFDVQWCPRDPLVFSAASFDGWINLYSVMGRSWEVQQMRQADKISSSFSKGQPLPPLQVPEQVAQASLIPPLKKPPKWMRRPAGVSFAFGGKLVTFGLPSTPVHQVPQPCLRLVFISQVTTEPELLAQSAELQEALGSGNLLNYCQNKIHQASLQSEKMLWQFLKVTLEKDARMKFLKLLGYSKDELQKKVATWLRSDLRLGEIPQSKGDDLNSNRQQAFSIQTSKHTTWEASVSSDFFDELIPQNMTLWEIPITEDTEGLLSRALLLGELGPAVELCLKEERFADAIILAQAGGSDLLKQAQERYLAKKKTGIAPLLACIIQKNWKDMVHACSLKNWREALALLLTYSEPEKFPELCDRLGTRMEQESGWALTSEARLCYVCSGSVERLVECWAKCQPASSPMALQDLMEKVMVLNRSLELLRGPDGVSPGPATTYRITQYANLLAAQGSLATAMSYLPSDCAQLPVQQLRDRLFHAQGSGVLGQQSPPFPFPRVVVGATPYSQETSSPRLKFQSSHQVPILPPRPRIFTPQSSLMMPLTPSHPSPYQGSRMQNTSDYRPSGVQEAQPLPLGPGVRPALSQPQLLGGQRAQAPNPVGFPGTWPLLAPPMAPPNIMQPGSVPLPRAPPVHPLFPVRAPGFSPMSSQPPAPPVSFPAAHPPGGPGTPCAGVLPTTGILIPHPGPQDSLKNAPVPKGNLQRKKQCQQPLDKINRKELPPEHQSLKISFEALLQRCSLSATDLKTKRKLDEAAQRLECLYDKLCEGTLSPPVLAGLHEIARCVDAGSPEQGLAMHAQVVGCSSFSEVSSFMPVLKSVLTIAHKLRV", "length": 1127, "header": "tr|E1BLS3-1|E1BLS3_BOVIN Isoform 1 of Protein transport protein Sec31B OS=Bos taurus OX=9913 GN=SEC31B PE=3 SV=3 CANONICAL=E1BLS3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LL46-1", "url": "https://www.uniprot.org/uniprotkb/E1BLS3/entry#A0A3Q1LL46-1", "sequence": { "sequence": 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"length": 1122, "header": "tr|A0A3Q1LL46-1|E1BLS3_BOVIN Computationally mapped isoform of Protein transport protein Sec31B OS=Bos taurus OX=9913 GN=SEC31B PE=3 SV=2 CANONICAL=E1BLS3-1" }, "locus": { "chromosome": "26", "start_pos": 21409613, "end_pos": 21378979, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084375.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084375.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057175.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057175.2" } ] } }, { "isoform_ac": "A0A3Q1M1L0-1", "url": "https://www.uniprot.org/uniprotkb/E1BLS3/entry#A0A3Q1M1L0-1", "sequence": { "sequence": "MKLKELERQAVQVWSPASQYPVYLATGTSAQQLDASFSTNGTLEIFEVDFRDPSLDLKRKGVLSASSRFHKLIWGSFGSGLLEASGVIAGGGDNGMLTLYNVTHVLSSGKEPVIAQRQKHSGAVRALDFNPFQGNLLASGANDSEIFIWDLNNLSVPMTPGSKSQQPLEDIKALSWNRQVQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLSSAKDSQILCWNLGSSEVVYKLPMLSSWCFDVQWCPRDPLVFSAASFDGWINLYSVMGRSWEVQQMRQADKISSSFSKGQPLPPLQVPEQVAQASLIPPLKKPPKWMRRPAGVSFAFGGKLVTFGLPSTPVHQVPQPCLRLVFISQVTTEPELLAQSAELQEALGSGNLLNYCQNKIHQASLQSEKMLWQFLKVTLEKDARMKFLKLLGYSKDELQKKVATWLRSDLRLGEIPQSKGDDLNSNRQQAFSIQTSKHTTWEASVSSDFFDELIPQNMTLWEIPITEDTEGLLSRALLLGELGPAVELCLKEERFADAIILAQAGGSDLLKQAQERYLAKKKTGIAPLLACIIQKNWKDMVHACSLKNWREALALLLTYSEPEKFPELCDRLGTRMEQESGWALTSEARLCYVCSGSVERLVECWAKCQPASSPMALQDLMEKVMVLNRSLELLRGPDGVSPGPATTYRITQYANLLAAQGSLATAMSYLPSDCAQLPVQQLRDRLFHAQGSGVLGQQSPPFPFPRVVVGATPYSQETSSPRLKFQSSHQVPILPPRPRIFTPQSSLMMPLTPSHPSPYQGSRMQNTSDYRPSGVQEAQPLPLGPGVRPALSQPQLLGGQRAQAPNPVGFPGTWPLLAPPMAPPNIMQPGSVPLPRAPPVHPLFPVRAPGFSPMSSQPPAPPVSFPAAHPPGGPGTPCAGVLPTTGILIPHPGPQDSLKNAPVPKGNLQRKKLPETFMPPAPITAPVMCLTPEPRGVLSSQPAVPSQCQQPLDKINRKELPPEHQSLKISFEALLQRCSLSATDLSADCLYGSQHKYFSSRNAG", "length": 1098, "header": "tr|A0A3Q1M1L0-1|E1BLS3_BOVIN Computationally mapped isoform of Protein transport protein Sec31B OS=Bos taurus OX=9913 GN=SEC31B PE=3 SV=2 CANONICAL=E1BLS3-1" }, "locus": { "chromosome": "26", "start_pos": 21409613, "end_pos": 21378979, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072520.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072520.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063620.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063620.2" } ] } }, { "isoform_ac": "E1BLS3-1", "url": "https://www.uniprot.org/uniprotkb/E1BLS3/entry#E1BLS3-1", "sequence": { "sequence": "MKLKELERQAVQVWSPASQYPVYLATGTSAQQLDASFSTNGTLEIFEVDFRDPSLDLKRKGVLSASSRFHKLIWGSFGSGLLEASGVIAGGGDNGMLTLYNVTHVLSSGKEPVIAQRQKHSGAVRALDFNPFQGNLLASGANDSEIFIWDLNNLSVPMTPGSKSQPLEDIKALSWNRQVQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLSSAKDSQILCWNLGSSEVVYKLPMLSSWCFDVQWCPRDPLVFSAASFDGWINLYSVMGRSWEVQQMRQADKISSSFSKGQPLPPLQVPEQVAQASLIPPLKKPPKWMRRPAGVSFAFGGKLVTFGLPSTPVHQVPQPCLRLVFISQVTTEPELLAQSAELQEALGSGNLLNYCQNKIHQASLQSEKMLWQFLKVTLEKDARMKFLKLLGYSKDELQKKVATWLRSDLRLGEIPQSKGDDLNSNRQQAFSIQTSKHTTWEASVSSDFFDELIPQNMTLWEIPITEDTEGLLSRALLLGELGPAVELCLKEERFADAIILAQAGGSDLLKQAQERYLAKKKTGIAPLLACIIQKNWKDMVHACSLKNWREALALLLTYSEPEKFPELCDRLGTRMEQESGWALTSEARLCYVCSGSVERLVECWAKCQPASSPMALQDLMEKVMVLNRSLELLRGPDGVSPGPATTYRITQYANLLAAQGSLATAMSYLPSDCAQLPVQQLRDRLFHAQGSGVLGQQSPPFPFPRVVVGATPYSQETSSPRLKFQSSHQVPILPPRPRIFTPQSSLMMPLTPSHPSPYQGSRMQNTSDYRPSGVQEAQPLPLGPGVRPALSQPQLLGGQRAQAPNPVGFPGTWPLLAPPMAPPNIMQPGSVPLPRAPPVHPLFPVRAPGFSPMSSQPPAPPVSFPAAHPPGGPGTPCAGVLPTTGILIPHPGPQDSLKNAPVPKGNLQRKKQCQQPLDKINRKELPPEHQSLKISFEALLQRCSLSATDLKTKRKLDEAAQRLECLYDKLCEGTLSPPVLAGLHEIARCVDAGSPEQGLAMHAQVVGCSSFSEVSSFMPVLKSVLTIAHKLRV", "length": 1127, "header": "tr|E1BLS3-1|E1BLS3_BOVIN Isoform 1 of Protein transport protein Sec31B OS=Bos taurus OX=9913 GN=SEC31B PE=3 SV=3 CANONICAL=E1BLS3-1" }, "locus": { "chromosome": "26", "start_pos": 21409613, "end_pos": 21381049, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000099.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000099.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000099.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000099.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 977, "start_aa": "Thr", "end_pos": 977, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr977", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ], "pmid": "" }, { "name": "COPII-coated vesicle cargo loading", "id": "GO:0090110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090110", "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ], "pmid": "" }, { "name": "endoplasmic reticulum organization", "id": "GO:0007029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007029", "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "E1BLS3", "url": "https://www.uniprot.org/uniprotkb/E1BLS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 721, "end_pos": 723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 859, "end_pos": 861, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 977 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 153, "end_pos": 155 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 550, "end_pos": 552 }, { "start_pos": 721, "end_pos": 723 }, { "start_pos": 859, "end_pos": 861 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NLP4-1", "uniprot_ac": "A0ABI0NLP4", "uniprot_id": "A0ABI0NLP4_BOVIN", "mass": { "chemical_mass": 22893.0, "monoisotopic_mass": 22893.0 }, "refseq": { "ac": "XP_005217099", "name": "small ribosomal subunit protein mS38 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217099" }, "gene_names": [ { "name": "AURKAIP1", "type": "recommended", "evidence": [ { "id": "A0ABI0NLP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4" } ] }, { "name": "AURKAIP1", "type": "synonym", "evidence": [ { "id": "XP_005217099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217099" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein bS22, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0ABI0NLP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4/entry#names_and_taxonomy" } ] }, { "name": "Small ribosomal subunit protein mS38", "type": "synonym", "evidence": [ { "id": "A0ABI0NLP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4/entry#names_and_taxonomy" } ] }, { "name": "small ribosomal subunit protein mS38 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005217099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217099" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLP4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AURKAIP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4", "locus": { "chromosome": "16", "start_pos": 51151855, "end_pos": 51147363, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004874", "url": "https://www.ensembl.org/id/ENSBTAG00000004874" } ] } } ], "crossref": [ { "id": "ENSBTAG00000004874", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004874", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23699", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23699", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506359", "url": "https://www.ncbi.nlm.nih.gov/gene/506359", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MIJ4", "url": "https://www.orthodb.org/?gene=F1MIJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32035", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32035", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32035:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32035:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08213", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08213", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005217099", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217099", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NLP4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLP4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6X0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6X0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6X0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIJ4", "url": "https://www.uniprot.org/uniprotkb/F1MIJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIJ4-1", "url": "https://www.uniprot.org/uniprotkb/F1MIJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLMRLTSQLLRAVPRAGCSGPWPVLGVLGRHACRPCYSTKPTGPSGVASLPGRRVHMELEEMLVPRKMSISPLESWLTIRYLLPRLDTGAPGTVSPAQLYECPPSQVGEGVEQGGKDVFDAPQMQCRNVLKIRRRKMNHHKYRKLVKRTRFLRRKVREARLKRKQMKFERDLRRIWQKAGLKEAPPGWQTPKIYLKGK", "length": 199, "header": "tr|A0ABI0NLP4-1|A0ABI0NLP4_BOVIN Isoform 1 of Small ribosomal subunit protein bS22, mitochondrial OS=Bos taurus OX=9913 GN=AURKAIP1 PE=3 SV=1 CANONICAL=A0ABI0NLP4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NLP4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4/entry#A0ABI0NLP4-1", "sequence": { "sequence": "MFLMRLTSQLLRAVPRAGCSGPWPVLGVLGRHACRPCYSTKPTGPSGVASLPGRRVHMELEEMLVPRKMSISPLESWLTIRYLLPRLDTGAPGTVSPAQLYECPPSQVGEGVEQGGKDVFDAPQMQCRNVLKIRRRKMNHHKYRKLVKRTRFLRRKVREARLKRKQMKFERDLRRIWQKAGLKEAPPGWQTPKIYLKGK", "length": 199, "header": "tr|A0ABI0NLP4-1|A0ABI0NLP4_BOVIN Isoform 1 of Small ribosomal subunit protein bS22, mitochondrial OS=Bos taurus OX=9913 GN=AURKAIP1 PE=3 SV=1 CANONICAL=A0ABI0NLP4-1" }, "locus": { "chromosome": "16", "start_pos": 51151800, "end_pos": 51147842, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152100.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152100.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106087.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106087.1" } ] } }, { "isoform_ac": "A0ABI0P6X0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4/entry#A0ABI0P6X0-1", "sequence": { "sequence": "MDMGRKKSNTSCSGPWPVLGVLGRHACRPCYSTKPTGPSGVASLPGRRVHMELEEMLVPRKMSISPLESWLTIRYLLPRLDTGAPGTVSPAQLYECPPSQVGEGVEQGGKDVFDAPQMQCRNVLKIRRRKMNHHKYRKLVKRTRFLRRKVREARLKRKQMKFERDLRRIWQKAGLKEAPPGWQTPKIYLKGK", "length": 192, "header": "tr|A0ABI0P6X0-1|A0ABI0P6X0_BOVIN Computationally mapped isoform of Small ribosomal subunit protein bS22, mitochondrial OS=Bos taurus OX=9913 GN=AURKAIP1 PE=3 SV=1 CANONICAL=A0ABI0NLP4-1" }, "locus": { "chromosome": "16", "start_pos": 51151800, "end_pos": 51149274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146969.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146969.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106822.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106822.1" } ] } }, { "isoform_ac": "F1MIJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4/entry#F1MIJ4-1", "sequence": { "sequence": "MDENRQPCSHPDVTEGCSGPWPVLGVLGRHACRPCYSTKPTGPSGVASLPGRRVHMELEEMLVPRKMSISPLESWLTIRYLLPRLDTGAPGTVSPAQLYECPPSQVGEGVEQGGKDVFDAPQMQCRNVLKIRRRKMNHHKYRKLVKRTRFLRRKVREARLKRKQMKFERDLRRIWQKAGLKEAPPGWQTPKIYLKGK", "length": 197, "header": "tr|F1MIJ4-1|A0ABI0NLP4_BOVIN Computationally mapped isoform of Small ribosomal subunit protein bS22, mitochondrial OS=Bos taurus OX=9913 GN=AURKAIP1 PE=3 SV=2 CANONICAL=A0ABI0NLP4-1" }, "locus": { "chromosome": "16", "start_pos": 51151800, "end_pos": 51150996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006409.5", "url": "https://www.ensembl.org/id/ENSBTAT00000006409.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006409.4", "url": "https://www.ensembl.org/id/ENSBTAP00000006409.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-BTA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-BTA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLP4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NLP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP4" }, { "id": "SM01155", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01155" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosomal protein mS38 C-terminal", "eco_id": "ECO_0000259", "start_pos": 126, "end_pos": 159, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NL02-1", "uniprot_ac": "A0ABI0NL02", "uniprot_id": "A0ABI0NL02_BOVIN", "mass": { "chemical_mass": 57391.0, "monoisotopic_mass": 57391.0 }, "refseq": { "ac": "NP_001415627", "name": "raftlin-2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001415627" }, "gene_names": [ { "name": "RFTN2", "type": "recommended", "evidence": [ { "id": "A0ABI0NL02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL02" } ] }, { "name": "RFTN2", "type": "synonym", "evidence": [ { "id": "NP_001415627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001415627" } ] } ], "protein_names": [ { "name": "Raftlin family member 2", "type": "synonym", "evidence": [ { "id": "A0ABI0NL02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL02/entry#names_and_taxonomy" } ] }, { "name": "raftlin-2 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001415627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001415627" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL02", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL02" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RFTN2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL02", "locus": { "chromosome": "2", "start_pos": 86102214, "end_pos": 86158087, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007652", "url": "https://www.ensembl.org/id/ENSBTAG00000007652" } ] } } ], "crossref": [ { "id": "ENSBTAG00000007652", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007652", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505671", "url": "https://www.ncbi.nlm.nih.gov/gene/505671", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LSR7", "url": "https://www.orthodb.org/?gene=A0A3Q1LSR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MMH5", "url": "https://www.orthodb.org/?gene=F1MMH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17601", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17601", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17601:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17601:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001415627", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001415627", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSR7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL02", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL02-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM87", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM87-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MMH5", "url": "https://www.uniprot.org/uniprotkb/F1MMH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MMH5-1", "url": "https://www.uniprot.org/uniprotkb/F1MMH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLCLNIASTYFAMGCGLRKLEDPDDSSPGKIFSTLKRPQVETKTEFAYEYVLLDFTLQASPNPEVIKINSILDIVTKVEDYYLKGYIVGAIHPVIQPVGQQKHLPASYLYRVVLSRLKLSTKHSTAPSGQRRPRLVIEECPLTYETQTNDVTKELIEKVNVAAKRGMRFVGFISQHYPPLKFCNGTNLDGDIESTLHVRRSPEENCKNWNEGTLSGQSSESGIEEELHRESGQCQMERDGSPSFSKSRKGEDNKLYTVFNVFDDESTCWNYQEGILSMKVTRKGSVISTLDADWLELTTFYYKQGLSLIDSFVCWETSKGDQLSKSLEGVFIYEEEGSGVPGFSRKGNDAIVVEQWTVIEGCEIKTDYGPLLHTLAEFGWLLTSVLPTPILRHDSEGNLATKQVVFLQRPVMWNSAAQTPERKGSRHVKGEDRSKVPSRSVSLDTDLLQPAESRSPPEECLLAPSRECWMKKRPAQPSSFSGFSNSDSVLRELDDGQFDQEDGVTQVTCM", "length": 511, "header": "tr|A0ABI0NL02-1|A0ABI0NL02_BOVIN Isoform 1 of Raftlin family member 2 OS=Bos taurus OX=9913 GN=RFTN2 PE=3 SV=1 CANONICAL=A0ABI0NL02-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LSR7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL02/entry#A0A3Q1LSR7-1", "sequence": { "sequence": "MGCGLRKLEDPDDSSPGKIFSTLKRPQVETKTEFAYEYVLLDFTLQASPNPEVIKINSILDIVTKVEDYYLKGYIVGAIHPVIQPVGQQKHLPASYLYRVVLSRLKLSTKHSTAPSGQRRPRLVIEECPLTYETQTNDVTKELIEKVNVAAKRGMRFVGFISQHYPPLKFCNGTNLDGDIESTLHVRRSPEENCKNWNEGTLSGQSSESGIEEELHRESGQCQMERDGSPSFSKSRKGEDNKLYTVFNVFDDESTCWNYQEGILSMKVTRKGSVISTLDADWLELTTFYYKQGLSLIDSFVCWETSKGDQLSKSLEGVFIYEEEGSGVPGFSRKGNDAIVVEQWTVIEGCEIKTDYGPLLHTLAEFGWLLTSVLPTPILRHDSEGNLATKQVVFLQRPVMWNSAAQTPERKGSRHVKGEDRSKVPSRSVSLDTDLLQPAESRSPPEECLLAPSRECWMKKRPAQPSSFSGFSNSDSVLRELDDGQFDQEDGVTQVTCM", "length": 498, "header": "tr|A0A3Q1LSR7-1|A0ABI0NL02_BOVIN Computationally mapped isoform of Raftlin family member 2 OS=Bos taurus OX=9913 GN=RFTN2 PE=3 SV=3 CANONICAL=A0ABI0NL02-1" }, "locus": { "chromosome": "2", "start_pos": 86177698, "end_pos": 86102274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084785.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084785.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058129.3", "url": "https://www.ensembl.org/id/ENSBTAP00000058129.3" } ] } }, { "isoform_ac": "A0ABI0NL02-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL02/entry#A0ABI0NL02-1", "sequence": { "sequence": "MPLCLNIASTYFAMGCGLRKLEDPDDSSPGKIFSTLKRPQVETKTEFAYEYVLLDFTLQASPNPEVIKINSILDIVTKVEDYYLKGYIVGAIHPVIQPVGQQKHLPASYLYRVVLSRLKLSTKHSTAPSGQRRPRLVIEECPLTYETQTNDVTKELIEKVNVAAKRGMRFVGFISQHYPPLKFCNGTNLDGDIESTLHVRRSPEENCKNWNEGTLSGQSSESGIEEELHRESGQCQMERDGSPSFSKSRKGEDNKLYTVFNVFDDESTCWNYQEGILSMKVTRKGSVISTLDADWLELTTFYYKQGLSLIDSFVCWETSKGDQLSKSLEGVFIYEEEGSGVPGFSRKGNDAIVVEQWTVIEGCEIKTDYGPLLHTLAEFGWLLTSVLPTPILRHDSEGNLATKQVVFLQRPVMWNSAAQTPERKGSRHVKGEDRSKVPSRSVSLDTDLLQPAESRSPPEECLLAPSRECWMKKRPAQPSSFSGFSNSDSVLRELDDGQFDQEDGVTQVTCM", "length": 511, "header": "tr|A0ABI0NL02-1|A0ABI0NL02_BOVIN Isoform 1 of Raftlin family member 2 OS=Bos taurus OX=9913 GN=RFTN2 PE=3 SV=1 CANONICAL=A0ABI0NL02-1" }, "locus": { "chromosome": "2", "start_pos": 86178168, "end_pos": 86102274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139974.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139974.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105575.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105575.1" } ] } }, { "isoform_ac": "A0ABI0NM87-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL02/entry#A0ABI0NM87-1", "sequence": { "sequence": "MSDSVRPHRRQPTRPRRPWDSPASPNPEVIKINSILDIVTKVEDYYLKGYIVGAIHPVIQPVGQQKHLPASYLYRVVLSRLKLSTKHSTAPSGQRRPRLVIEECPLTYETQTNDVTKELIEKVNVAAKRGMRFVGFISQHYPPLKFCNGTNLDGDIESTLHVRRSPEENCKNWNEGTLSGQSSESGIEEELHRESGQCQMERDGSPSFSKSRKGEDNKLYTVFNVFDDESTCWNYQEGILSMKVTRKGSVISTLDADWLELTTFYYKQGLSLIDSFVCWETSKGDQLSKSLEGVFIYEEEGSGVPGFSRKGNDAIVVEQWTVIEGCEIKTDYGPLLHTLAEFGWLLTSVLPTPILRHDSEGNLATKQVVFLQRPVMWNSAAQTPERKGSRHVKGEDRSKVPSRSVSLDTDLLQPAESRSPPEECLLAPSRECWMKKRPAQPSSFSGFSNSDSVLRELDDGQFDQEDGVTQVTCM", "length": 474, "header": "tr|A0ABI0NM87-1|A0ABI0NM87_BOVIN Computationally mapped isoform of Raftlin family member 2 OS=Bos taurus OX=9913 GN=RFTN2 PE=3 SV=1 CANONICAL=A0ABI0NL02-1" }, "locus": { "chromosome": "2", "start_pos": 86165610, "end_pos": 86102274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154173.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154173.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106479.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106479.1" } ] } }, { "isoform_ac": "F1MMH5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL02/entry#F1MMH5-1", "sequence": { "sequence": "MCTSPNPEVIKINSILDIVTKVEDYYLKGYIVGAIHPVIQPVGQQKHLPASYLYRVVLSRLKLSTKHSTAPSGQRRPRLVIEECPLTYETQTNDVTKELIEKVNVAAKRGMRFVGFISQHYPPLKFCNGTNLDGDIESTLHVRRSPEENCKNWNEGTLSGQSSESGIEEELHRESGQCQMERDGSPSFSKSRKGEDNKLYTVFNVFDDESTCWNYQEGILSMKVTRKGSVISTLDADWLELTTFYYKQGLSLIDSFVCWETSKGDQLSKSLEGVFIYEEEGSGVPGFSRKGNDAIVVEQWTVIEGCEIKTDYGPLLHTLAEFGWLLTSVLPTPILRHDSEGNLATKQVVFLQRPVMWNSAAQTPERKGSRHVKGEDRSKVPSRSVSLDTDLLQPAESRSPPEECLLAPSRECWMKKRPAQPSSFSGFSNSDSVLRELDDGQFDQEDGVTQVTCM", "length": 454, "header": "tr|F1MMH5-1|A0ABI0NL02_BOVIN Computationally mapped isoform of Raftlin family member 2 OS=Bos taurus OX=9913 GN=RFTN2 PE=3 SV=4 CANONICAL=A0ABI0NL02-1" }, "locus": { "chromosome": "2", "start_pos": 86175517, "end_pos": 86102274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010067.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010067.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010067.7", "url": "https://www.ensembl.org/id/ENSBTAP00000010067.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL02", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NKZ8-1", "uniprot_ac": "A0ABI0NKZ8", "uniprot_id": "A0ABI0NKZ8_BOVIN", "mass": { "chemical_mass": 164455.0, "monoisotopic_mass": 164455.0 }, "refseq": {}, "gene_names": [ { "name": "NRXN1", "type": "recommended", "evidence": [ { "id": "A0ABI0NKZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8" } ] } ], "protein_names": [ { "name": "Neurexin-1", "type": "recommended", "evidence": [ { "id": "A0ABI0NKZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8/entry#names_and_taxonomy" } ] }, { "name": "Neurexin I-alpha", "type": "synonym", "evidence": [ { "id": "A0ABI0NKZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8/entry#names_and_taxonomy" } ] }, { "name": "Neurexin-1-alpha", "type": "synonym", "evidence": [ { "id": "A0ABI0NKZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKZ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NRXN1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000046199", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046199", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "281950", "url": "https://www.ncbi.nlm.nih.gov/gene/281950", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036:SF90", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036:SF90", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NKZ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP04", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP04-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P370", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P370", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P370-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P370-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P585", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P585", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P585-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P585-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MN62", "url": "https://www.uniprot.org/uniprotkb/F1MN62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MN62-1", "url": "https://www.uniprot.org/uniprotkb/F1MN62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWM9", "url": "https://www.uniprot.org/uniprotkb/G3MWM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWM9-1", "url": "https://www.uniprot.org/uniprotkb/G3MWM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTALLQRGGCFLLCLSLLLLGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLTDTPVNDGAWHNVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSLALPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSRETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPVSQTTDDILVASAECPSDDEDIDPCEPSSANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV", "length": 1496, "header": "tr|A0ABI0NKZ8-1|A0ABI0NKZ8_BOVIN Isoform 1 of Neurexin-1 OS=Bos taurus OX=9913 GN=NRXN1 PE=3 SV=1 CANONICAL=A0ABI0NKZ8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NKZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8/entry#A0ABI0NKZ8-1", "sequence": { "sequence": "MGTALLQRGGCFLLCLSLLLLGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLTDTPVNDGAWHNVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSLALPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSRETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPVSQTTDDILVASAECPSDDEDIDPCEPSSANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV", "length": 1496, "header": "tr|A0ABI0NKZ8-1|A0ABI0NKZ8_BOVIN Isoform 1 of Neurexin-1 OS=Bos taurus OX=9913 GN=NRXN1 PE=3 SV=1 CANONICAL=A0ABI0NKZ8-1" }, "locus": { "chromosome": "11", "start_pos": 33524045, "end_pos": 32278507, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145300.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145300.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105548.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105548.1" } ] } }, { "isoform_ac": "A0ABI0NP04-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8/entry#A0ABI0NP04-1", "sequence": { "sequence": "MGTALLQRGGCFLLCLSLLLLGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLTDTPVNDGAWHNVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSLALPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQGLAHLMMGDQGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSRETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLGKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPVSQTTDDILVASAECPSDDEDIDPCEPSSANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV", "length": 1485, "header": "tr|A0ABI0NP04-1|A0ABI0NP04_BOVIN Computationally mapped isoform of Neurexin-1 OS=Bos taurus OX=9913 GN=NRXN1 PE=3 SV=1 CANONICAL=A0ABI0NKZ8-1" }, "locus": { "chromosome": "11", "start_pos": 33524045, "end_pos": 32278507, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151793.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151793.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107630.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107630.1" } ] } }, { "isoform_ac": "A0ABI0P370-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8/entry#A0ABI0P370-1", "sequence": { "sequence": "MGTALLQRGGCFLLCLSLLLLGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLTDTPVNDGAWHNVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSLALPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQGLAHLMMGDQGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSRETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLGKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPVSQTTDDILVASAECPSDDEDIDPCEPSSANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV", "length": 1462, "header": "tr|A0ABI0P370-1|A0ABI0P370_BOVIN Computationally mapped isoform of Neurexin-1 OS=Bos taurus OX=9913 GN=NRXN1 PE=3 SV=1 CANONICAL=A0ABI0NKZ8-1" }, "locus": { "chromosome": "11", "start_pos": 33524045, "end_pos": 32278507, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137988.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137988.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107378.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107378.1" } ] } }, { "isoform_ac": "A0ABI0P585-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8/entry#A0ABI0P585-1", "sequence": { "sequence": "MGTALLQRGGCFLLCLSLLLLGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLTDTPVNDGAWHNVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSLALPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSRETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLGKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPVSQTTDDILVASAECPSDDEDIDPCEPSSANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV", "length": 1482, "header": "tr|A0ABI0P585-1|A0ABI0P585_BOVIN Computationally mapped isoform of Neurexin-1 OS=Bos taurus OX=9913 GN=NRXN1 PE=3 SV=1 CANONICAL=A0ABI0NKZ8-1" }, "locus": { "chromosome": "11", "start_pos": 33524045, "end_pos": 32278507, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145231.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145231.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106856.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106856.1" } ] } }, { "isoform_ac": "F1MN62-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8/entry#F1MN62-1", "sequence": { "sequence": "MYQRMLRCGAELGSPGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIHHFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPVSQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV", "length": 467, "header": "tr|F1MN62-1|A0ABI0NKZ8_BOVIN Computationally mapped isoform of Neurexin-1 OS=Bos taurus OX=9913 GN=NRXN1 PE=3 SV=4 CANONICAL=A0ABI0NKZ8-1" }, "locus": { "chromosome": "11", "start_pos": 32765957, "end_pos": 32278507, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047691.5", "url": "https://www.ensembl.org/id/ENSBTAT00000047691.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044872.5", "url": "https://www.ensembl.org/id/ENSBTAP00000044872.5" } ] } }, { "isoform_ac": "G3MWM9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8/entry#G3MWM9-1", "sequence": { "sequence": "MDMRWHCENSQTTDDILVASAECPSDDEDIDPCEPSSANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV", "length": 139, "header": "tr|G3MWM9-1|A0ABI0NKZ8_BOVIN Computationally mapped isoform of Neurexin-1 OS=Bos taurus OX=9913 GN=NRXN1 PE=3 SV=3 CANONICAL=A0ABI0NKZ8-1" }, "locus": { "chromosome": "11", "start_pos": 32343039, "end_pos": 32278507, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064537.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064537.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053932.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053932.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKZ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKZ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKZ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1215, "end_pos": 1217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 782, "end_pos": 784, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NKZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 219, "end_pos": 256, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NKZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKZ8" }, { "id": "PS50025", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50025" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin G", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 217, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1215, "end_pos": 1217 }, { "start_pos": 125, "end_pos": 127 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 782, "end_pos": 784 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NLQ9-1", "uniprot_ac": "A0ABI0NLQ9", "uniprot_id": "A0ABI0NLQ9_BOVIN", "mass": { "chemical_mass": 177940.0, "monoisotopic_mass": 177940.0 }, "refseq": { "ac": "XP_005228454", "name": "actin remodeling regulator NHS isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228454" }, "gene_names": [ { "name": "NHS", "type": "recommended", "evidence": [ { "id": "A0ABI0NLQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9" } ] }, { "name": "NHS", "type": "synonym", "evidence": [ { "id": "XP_005228454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228454" } ] } ], "protein_names": [ { "name": "NHS actin remodeling regulator", "type": "synonym", "evidence": [ { "id": "A0ABI0NLQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9/entry#names_and_taxonomy" } ] }, { "name": "actin remodeling regulator NHS isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005228454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228454" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLQ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NHS", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9", "locus": { "chromosome": "X", "start_pos": 125753588, "end_pos": 126082506, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000039195", "url": "https://www.ensembl.org/id/ENSBTAG00000039195" } ] } } ], "crossref": [ { "id": "ENSBTAG00000039195", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039195", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539895", "url": "https://www.ncbi.nlm.nih.gov/gene/539895", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LVM8", "url": "https://www.orthodb.org/?gene=A0A3Q1LVM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MI31", "url": "https://www.orthodb.org/?gene=A0A3Q1MI31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MWH1", "url": "https://www.orthodb.org/?gene=F1MWH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X6S6", "url": "https://www.orthodb.org/?gene=G3X6S6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23039", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23039", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23039:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23039:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005228454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228454", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MI31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MI31-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLQ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MWH1", "url": "https://www.uniprot.org/uniprotkb/F1MWH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MWH1-1", "url": "https://www.uniprot.org/uniprotkb/F1MWH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6S6", "url": "https://www.uniprot.org/uniprotkb/G3X6S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6S6-1", "url": "https://www.uniprot.org/uniprotkb/G3X6S6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFAKRIVEPQWLCRQRRPAPDLAEDAIGGSAEPPPPPPLQLPGRRDEAVAPGPEDPPRAPPAPPGPPPPAPTDQAPPPHGEAPAAGEESVAGVLEAASVAGEASSAAATAVLLMLDLCAVSNAALARVLRQLSDVARHACSLFQELESDIQLTHRRVWALQGKLGGVQRVLGTLDPKQEAVPVSNLDVESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRQARQSLQALRREHRSRSDRREQRAAAPISVAAPPLPAYPPAHSQRRREAKDRHFLTFNSTRSPSPTECCHMTPWSRKSHPPEDEDTDVMLGQRPKNPVHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISSCIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVARERNVIVHTNPDPSNTVNRRSGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAGNISALADKGDTVFTTAVSSRTRSRSLPREGNRGGDAEPKVGAKPSAYEEGEPFVGDQERTLTDCSEAPNSPSAQEHQPALSLACSQHLHSPQHKLNERGRSRLSRMAADSGSCDISSNSDTFGSPIHCISTAGVLLSSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNTAPHANEDTSVFVTEQYNDQLEKVRGHRTNSFTSTVADLLDDPNNSNTSDSEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVDTEGYYTSMHFDCGLKGSKNYVCHYAALGPENSQGIGVPPALSDCAWQDYLDHRRQGRPSISFRKPKAKPTPPKRSSSLRKSDGNADTSEKKEPKTSSGQLLPHSSREMKLPLDFSNTPSLMENANLPTKPEPSWMNQNEHGIKEPQLDTPDVPPFKDEGAESTHYADLWLLNDLKTNDPYRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFKLASPEKLAGLASPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGALSLSKDLELPIIPPTHLDLSALHNVLNKPFHHRHPLHVFSHNKQNTVGETLRSNPPPSLAITPTVLKSVNLRSISKSEEVKQKEGNNTDLPYLEESTLTTGKIRPHVIKKSLPCQYTTEDTILSFLDSSAVEMGPDKLQLEKKHTFDVKHHCDPETVTSAGSNLLDSSVTRDQMHMESEPVSENKPSKSCDFLTEGFQRVSAARPNDSDGKTLQYGAGPDGALAQVQKLSFVDREEAAPPESVDVLTPQSDSPTRVTDIGYQLKPQLGMSHHHDKVPGNISSEAEISTINPCPEKCSEQENIASGISAKSASDNSGAEETQGSVDEVSLKESSPSDDSVISPLSEDSQAEAESVFVSPNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRASLGSSSSNSAGSVTSPNSNVTTPNSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPILPKPPGDLTAESPQSPHEAHQGSPGTEALSPLSPCSPRVNAEGFSSKNFATSASARVGRSRAPPVASSSRYSVRCRLYNAPMQAISEGETENSDGSPHDDRSSQSST", "length": 1641, "header": "tr|A0ABI0NLQ9-1|A0ABI0NLQ9_BOVIN Isoform 1 of NHS actin remodeling regulator OS=Bos taurus OX=9913 GN=NHS PE=4 SV=1 CANONICAL=A0ABI0NLQ9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVM8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9/entry#A0A3Q1LVM8-1", "sequence": { "sequence": "MGGWCFLCGSAAVCSIKDCFHPHFLDEETQAPRTVSNLDVESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRQARQSLQALRREHRSRSDRREQRAAAPISVAAPPLPAYPPAHSQRRREAKDRHFLTFNSTRSPSPTECCHMTPWSRKSHPPEDEDTDVMLGQRPKNPVHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISSCIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVARERNVIVHTNPDPSNTVNRRSGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAGNISALADKGDTVFTTAVSSRTRSRSLPREGNRGGDAEPKVGAKPSAYEEGEPFVGDQERTLTDCSEAPNSPSAQEHQPALSLACSQHLHSPQHKLNERGRSRLSRMAADSGSCDISSNSDTFGSPIHCISTAGVLLSSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNTAPHANEDTSVFVTEQYNDQLEKVRGHRTNSFTSTVADLLDDPNNSNTSDSEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVDTEGYYTSMHFDCGLKGSKNYVCHYAALGPENSQGIGVPPALSDCAWQDYLDHRRQGRPSISFRKPKAKPTPPKRSSSLRKSDGNADTSEKKEPKTSSGQLLPHSSREMKLPLDFSNTPSLMENANLPTKPEPSWMNQNEHGIKEPQLDTPDVPPFKDEGAESTHYADLWLLNDLKTNDPYRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFKLASPEKLAGLASPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGALSLSKDLELPIIPPTHLDLSALHNVLNKPFHHRHPLHVFSHNKQNTVGETLRSNPPPSLAITPTVLKSVNLRSISKSEEVKQKEGNNTDLPYLEESTLTTGKIRPHVIKKSLPCQYTTEDTILSFLDSSAVEMGPDKLQLEKKHTFDVKHHCDPETVTSAGSNLLDSSVTRDQMHMESEPVSENKPSKSCDFLTEGFQRVSAARPNDSDGKTLQYGAGPDGALAQVQKLSFVDREEAAPPESVDVLTPQSDSPTRVTDIGYQLKPQLGMSHHHDKVPGNISSEAEISTINPCPEKCSEQENIASGISAKSASDNSGAEETQGSVDEVSLKESSPSDDSVISPLSEDSQAEAESVFVSPNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRASLGSSSSNSAGSVTSPNSNVTTPNSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPILPKPPGDLTAESPQSPHEAHQGSPGTEALSPLSPCSPRVNAEGFSSKNFATSASARVGRSRAPPVASSSRYSVRCRLYNAPMQAISEGETENSDGSPHDDRSSQSST", "length": 1492, "header": "tr|A0A3Q1LVM8-1|A0ABI0NLQ9_BOVIN Computationally mapped isoform of NHS actin remodeling regulator OS=Bos taurus OX=9913 GN=NHS PE=4 SV=2 CANONICAL=A0ABI0NLQ9-1" }, "locus": { "chromosome": "X", "start_pos": 126076924, "end_pos": 125753665, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074511.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074511.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061231.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061231.2" } ] } }, { "isoform_ac": "A0A3Q1MI31-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9/entry#A0A3Q1MI31-1", "sequence": { "sequence": "MRKPKLQELPSQHGELQVPALRMATRKAEDKPLRSRALETKRLQSTAVSNLDVESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRQARQSLQALRREHRSRSDRREQRAAAPISVAAPPLPAYPPAHSQRRREAKDRHFLTFNSTRSPSPTECCHMTPWSRKSHPPEDEDTDVMLGQRPKNPVHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISSCIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVARERNVIVHTNPDPSNTVNRRSGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAGNISALADKGDTVFTTAVSSRTRSRSLPREGNRGGDAEPKVGAKPSAYEEGEPFVGDQERTLTDCSEAPNSPSAQEHQPALSLACSQHLHSPQHKLNERGRSRLSRMAADSGSCDISSNSDTFGSPIHCISTAGVLLSSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNTAPHANEDTSVFVTEQYNDQLEKVRGHRTNSFTSTVADLLDDPNNSNTSDSEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVDTEGYYTSMHFDCGLKGSKNYVCHYAALGPENSQGIGVPPALSDCAWQDYLDHRRQGRPSISFRKPKAKPTPPKRSSSLRKSDGNADTSEKKEPKTSSGQLLPHSSREMKLPLDFSNTPSLMENANLPTKPEPSWMNQNEHGIKEPQLDTPDVPPFKDEGAESTHYADLWLLNDLKTNDPYRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFKLASPEKLAGLASPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGALSLSKDLELPIIPPTHLDLSALHNVLNKPFHHRHPLHVFSHNKQNTVGETLRSNPPPSLAITPTVLKSVNLRSISKSEEVKQKEGNNTDLPYLEESTLTTGKIRPHVIKKSLPCQYTTEDTILSFLDSSAVEMGPDKLQLEKKHTFDVKHHCDPETVTSAGSNLLDSSVTRDQMHMESEPVSENKPSKSCDFLTEGFQRVSAARPNDSDGKTLQYGAGPDGALAQVQKLSFVDREEAAPPESVDVLTPQSDSPTRVTDIGYQLKPQLGMSHHHDKVPGNISSEAEISTINPCPEKCSEQENIASGISAKSASDNSGAEETQGSVDEVSLKESSPSDDSVISPLSEDSQAEAESVFVSPNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRASLGSSSSNSAGSVTSPNSNVTTPNSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPILPKPPGDLTAESPQSPHEAHQGSPGTEALSPLSPCSPRVNAEGFSSKNFATSASARVGRSRAPPVASSSRYSVRCRLYNAPMQAISEGETENSDGSPHDDRSSQSST", "length": 1505, "header": "tr|A0A3Q1MI31-1|A0ABI0NLQ9_BOVIN Computationally mapped isoform of NHS actin remodeling regulator OS=Bos taurus OX=9913 GN=NHS PE=4 SV=2 CANONICAL=A0ABI0NLQ9-1" }, "locus": { "chromosome": "X", "start_pos": 126010664, "end_pos": 125753665, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069614.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069614.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070908.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070908.2" } ] } }, { "isoform_ac": "A0ABI0NLQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9/entry#A0ABI0NLQ9-1", "sequence": { "sequence": "MPFAKRIVEPQWLCRQRRPAPDLAEDAIGGSAEPPPPPPLQLPGRRDEAVAPGPEDPPRAPPAPPGPPPPAPTDQAPPPHGEAPAAGEESVAGVLEAASVAGEASSAAATAVLLMLDLCAVSNAALARVLRQLSDVARHACSLFQELESDIQLTHRRVWALQGKLGGVQRVLGTLDPKQEAVPVSNLDVESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRQARQSLQALRREHRSRSDRREQRAAAPISVAAPPLPAYPPAHSQRRREAKDRHFLTFNSTRSPSPTECCHMTPWSRKSHPPEDEDTDVMLGQRPKNPVHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISSCIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVARERNVIVHTNPDPSNTVNRRSGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAGNISALADKGDTVFTTAVSSRTRSRSLPREGNRGGDAEPKVGAKPSAYEEGEPFVGDQERTLTDCSEAPNSPSAQEHQPALSLACSQHLHSPQHKLNERGRSRLSRMAADSGSCDISSNSDTFGSPIHCISTAGVLLSSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNTAPHANEDTSVFVTEQYNDQLEKVRGHRTNSFTSTVADLLDDPNNSNTSDSEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVDTEGYYTSMHFDCGLKGSKNYVCHYAALGPENSQGIGVPPALSDCAWQDYLDHRRQGRPSISFRKPKAKPTPPKRSSSLRKSDGNADTSEKKEPKTSSGQLLPHSSREMKLPLDFSNTPSLMENANLPTKPEPSWMNQNEHGIKEPQLDTPDVPPFKDEGAESTHYADLWLLNDLKTNDPYRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFKLASPEKLAGLASPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGALSLSKDLELPIIPPTHLDLSALHNVLNKPFHHRHPLHVFSHNKQNTVGETLRSNPPPSLAITPTVLKSVNLRSISKSEEVKQKEGNNTDLPYLEESTLTTGKIRPHVIKKSLPCQYTTEDTILSFLDSSAVEMGPDKLQLEKKHTFDVKHHCDPETVTSAGSNLLDSSVTRDQMHMESEPVSENKPSKSCDFLTEGFQRVSAARPNDSDGKTLQYGAGPDGALAQVQKLSFVDREEAAPPESVDVLTPQSDSPTRVTDIGYQLKPQLGMSHHHDKVPGNISSEAEISTINPCPEKCSEQENIASGISAKSASDNSGAEETQGSVDEVSLKESSPSDDSVISPLSEDSQAEAESVFVSPNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRASLGSSSSNSAGSVTSPNSNVTTPNSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPILPKPPGDLTAESPQSPHEAHQGSPGTEALSPLSPCSPRVNAEGFSSKNFATSASARVGRSRAPPVASSSRYSVRCRLYNAPMQAISEGETENSDGSPHDDRSSQSST", "length": 1641, "header": "tr|A0ABI0NLQ9-1|A0ABI0NLQ9_BOVIN Isoform 1 of NHS actin remodeling regulator OS=Bos taurus OX=9913 GN=NHS PE=4 SV=1 CANONICAL=A0ABI0NLQ9-1" }, "locus": { "chromosome": "X", "start_pos": 126094968, "end_pos": 125753665, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147021.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147021.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106123.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106123.1" } ] } }, { "isoform_ac": "F1MWH1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9/entry#F1MWH1-1", "sequence": { "sequence": "MPLACCMPKNAAVSNLDVESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRQARQSLQALRREHRSRSDRREQRAAAPISVAAPPLPAYPPAHSQRRREAKDRHFLTFNSTRSPSPTECCHMTPWSRKSHPPEDEDTDVMLGQRPKNPVHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISSCIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVARERNVIVHTNPDPSNTVNRRSGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAGNISALADKGDTVFTTAVSSRTRSRSLPREGNRGGDAEPKVGAKPSAYEEGEPFVGDQERTLTDCSEAPNSPSAQEHQPALSLACSQHLHSPQHKLNERGRSRLSRMAADSGSCDISSNSDTFGSPIHCISTAGVLLSSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNTAPHANEDTSVFVTEQYNDQLEKVRGHRTNSFTSTVADLLDDPNNSNTSDSEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVDTEGYYTSMHFDCGLKGSKNYVCHYAALGPENSQGIGVPPALSDCAWQDYLDHRRQGRPSISFRKPKAKPTPPKRSSSLRKSDGNADTSEKKEPKTSSGQLLPHSSREMKLPLDFSNTPSLMENANLPTKPEPSWMNQNEHGIKEPQLDTPDVPPFKDEGAESTHYADLWLLNDLKTNDPYRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFKLASPEKLAGLASPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGALSLSKDLELPIIPPTHLDLSALHNVLNKPFHHRHPLHVFSHNKQNTVGETLRSNPPPSLAITPTVLKSVNLRSISKSEEVKQKEGNNTDLPYLEESTLTTGKIRPHVIKKSLPCQYTTEDTILSFLDSSAVEMGPDKLQLEKKHTFDVKHHCDPETVTSAGSNLLDSSVTRDQMHMESEPVSENKPSKSCDFLTEGFQRVSAARPNDSDGKTLQYGAGPDGALAQVQKLSFVDREEAAPPESVDVLTPQSDSPTRVTDIGYQLKPQLGMSHHHDKVPGNISSEAEISTINPCPEKCSEQENIASGISAKSASDNSGAEETQGSVDEVSLKESSPSDDSVISPLSEDSQAEAESVFVSPNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRASLGSSSSNSAGSVTSPNSNVTTPNSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPILPKPPGDLTAESPQSPHEAHQGSPGTEALSPLSPCSPRVNAEGFSSKNFATSASARVGRSRAPPVASSSRYSVRCRLYNAPMQAISEGETENSDGSPHDDRSSQSST", 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"length": 1526, "header": "tr|G3X6S6-1|A0ABI0NLQ9_BOVIN Computationally mapped isoform of NHS actin remodeling regulator OS=Bos taurus OX=9913 GN=NHS PE=4 SV=3 CANONICAL=A0ABI0NLQ9-1" }, "locus": { "chromosome": "X", "start_pos": 125839685, "end_pos": 125753665, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012640.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012640.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012640.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012640.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 341, "start_aa": "Thr", "end_pos": 341, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr341", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 844, "start_aa": "Thr", "end_pos": 844, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr844", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-BTA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLQ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9" } ], "pmid": "" }, { "name": "lens development in camera-type eye", "id": "GO:0002088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002088", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLQ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1152, "end_pos": 1154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1272, "end_pos": 1274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1345, "end_pos": 1347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1480, "end_pos": 1482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1501, "end_pos": 1503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": 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"end_pos": 282 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 476, "end_pos": 478 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 708, "end_pos": 710 }, { "start_pos": 711, "end_pos": 713 }, { "start_pos": 959, "end_pos": 961 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NIV2-1", "uniprot_ac": "A0ABI0NIV2", "uniprot_id": "A0ABI0NIV2_BOVIN", "mass": { "chemical_mass": 102238.0, "monoisotopic_mass": 102238.0 }, "refseq": {}, "gene_names": [ { "name": "ATP2C2", "type": "recommended", "evidence": [ { "id": "A0ABI0NIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ] } ], "protein_names": [ { "name": "Calcium-transporting ATPase", "type": "recommended", "evidence": [ { "id": "A0ABI0NIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2/entry#names_and_taxonomy" } ] }, { "name": "7.2.2.10", "type": "synonym", "evidence": [ { "id": "A0ABI0NIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "ATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway. Within a catalytic cycle, acquires Ca(2+) or Mn(2+) ions on the cytoplasmic side of the membrane and delivers them to the lumenal side. The transfer of ions across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing to outward-facing state. Induces Ca(2+) influx independently of its ATP-driven pump function. At the basolateral membrane of mammary epithelial cells, interacts with Ca(2+) channel ORAI1 and mediates Ca(2+) entry independently of the Ca(2+) content of endoplasmic reticulum or Golgi stores. May facilitate transepithelial transport of large quantities of Ca(2+) for milk secretion via activation of Ca(2+) influx channels at the plasma membrane and active Ca(2+) transport at the Golgi apparatus.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T3W6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3W6#function" }, { "database": "UniProtKB", "id": "ARBA00054616", "url": "https://www.uniprot.org/uniprotkb/ARBA00054616#function" }, { "database": "UniProtKB", "id": "A0AAA9TAU7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAU7#function" }, { "database": "UniProtKB", "id": "F1MMF3", "url": "https://www.uniprot.org/uniprotkb/F1MMF3#function" }, { "database": "UniProtKB", "id": "A0A3Q1LYD6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYD6#function" }, { "database": "UniProtKB", "id": "A0A3Q1MD53", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD53#function" }, { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2#function" } ] }, { "annotation": "Catalyzes the hydrolysis of ATP coupled with the transport of calcium.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T3W6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3W6#function" }, { "database": "UniProtKB", "id": "RU361146", "url": "https://www.uniprot.org/uniprotkb/RU361146#function" }, { "database": "UniProtKB", "id": "A0AAA9TAU7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAU7#function" }, { "database": "UniProtKB", "id": "F1MMF3", "url": "https://www.uniprot.org/uniprotkb/F1MMF3#function" }, { "database": "UniProtKB", "id": "A0A3Q1LYD6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYD6#function" }, { "database": "UniProtKB", "id": "A0A3Q1MD53", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD53#function" }, { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ATP2C2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2", "locus": { "chromosome": "18", "start_pos": 10684674, "end_pos": 10596307, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000945", "url": "https://www.ensembl.org/id/ENSBTAG00000000945" } ] } } ], "crossref": [ { "id": "ENSBTAG00000000945", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000945", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02085", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02085", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "510329", "url": "https://www.ncbi.nlm.nih.gov/gene/510329", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510329", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510329", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LYD6", "url": "https://www.orthodb.org/?gene=A0A3Q1LYD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MD53", "url": "https://www.orthodb.org/?gene=A0A3Q1MD53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MMF3", "url": "https://www.orthodb.org/?gene=F1MMF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42861", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42861", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00122", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00122", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00689", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00689", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-936837", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "18105", "url": "https://www.rhea-db.org/rhea/18105", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "66820", "url": "https://www.rhea-db.org/rhea/66820", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LYD6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MD53", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MD53-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3W6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3W6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAU7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAU7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NIV2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MMF3", "url": "https://www.uniprot.org/uniprotkb/F1MMF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MMF3-1", "url": "https://www.uniprot.org/uniprotkb/F1MMF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEGRFSRLLQKLAFWGSSHKYELLAKGELETLIDGQNDLKAIEKEKTVVALEPKEASKCHREDLAKAFYVDLQNGLSEFSVTQRRLVHGWNEFVADNTEPVWKKYLDQFKNPLILLLLASALVSVLTKKYEDAISIAVAVLIVVTVAFIQEYRSEKSLEELTKLVPPECNCIREGKLQHLLARDLVPGDIVSLSIGDRVPADIRLTEVTDLLVDESSFTGEAEPSSKTDTPLTGEGDLTTLSNIVFMGTLVQCGKGQGVVIGTGEKSQFGEVFKMMQAEETPKTPLQKSMDKLGKQLTLFSFGIIGLIMFTGWLQGKHLLSMFTIGVSLAVAAIPEGLPIVVTVTLVLGVLRMARKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTVTQLVTSDGLHAEVSGVGYNGNGTVCLLPSKEVIKQFSNVSVGKLVEAGCVANNAIIRKNTVMGQPTEGALVALAMKMDLGDIKDSYIRKKEIPFSSEQKWMAVQCSSKNEEREDMYFMKGAFEEVIRYCAMYNHGGIPLPLTPQQRAFCQQEEKKMGSLGLRVLALASGPELGKLTFLGLIGIIDPPRAGVKEAVQVLSESGLSVKMITGDALETALAIGRNVGLCNGKLSAMSGEEVESAEQGELAEHIGKVSVFYRTSPKHKLKIIKALQETGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDEFSAIMNAVEEGKGIFHNIKNFVRFQLSTSISALSLITLSTVCNLPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDTLRQPPRNVKDQILSRALVLRILLSATTIISGTLFIFWKEMPEDRASTPRTTTMAFTCFVFFDLFNALTCRSQTKLIFEIGFLRNRTFLYSVLGSILGQLAVIYTPPLQRVFQTESLGALGESEGSWGLSSLPARGVKSPRGAILSPGDWARA", "length": 940, "header": "tr|A0ABI0NIV2-1|A0ABI0NIV2_BOVIN Isoform 1 of Calcium-transporting ATPase OS=Bos taurus OX=9913 GN=ATP2C2 PE=3 SV=1 CANONICAL=A0ABI0NIV2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LYD6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2/entry#A0A3Q1LYD6-1", "sequence": { "sequence": "MGLLSWMQIDGQNDLKAIEKEKTVVALEPKEASKCHREDLAKAFYVDLQNGLSEFSVTQRRLVHGWNEFVADNTEPVWKKYLDQFKNPLILLLLASALVSVLTKKYEDAISIAVAVLIVVTVAFIQEYRSEKSLEELTKLVPPECNCIREGKLQHLLARDLVPGDIVSLSIGDRVPADIRLTEVTDLLVDESSFTGEAEPSSKTDTPLTGEGDLTTLSNIVFMGTLVQCGKGQGVVIGTGEKSQFGEVFKMMQAEETPKTPLQKSMDKLGKQLTLFSFGIIGLIMFTGWLQGKHLLSMFTIGVSLAVAAIPEGLPIVVTVTLVLGVLRMARKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTVTQLVTSDGLHAEVSGVGYNGNGTVCLLPSKEVIKQFSNVSVGKLVEAGCVANNAIIRKNTVMGQPTEGALVALAMKMDLGDIKDSYIRKKEIPFSSEQKWMAVQCSSKNEEREDMYFMKGAFEEVIRYCAMYNHGGIPLPLTPQQRAFCQQEEKKMGSLGLRVLALASGPELGKLTFLGLIGIIDPPRAGVKEAVQVLSESGLSVKMITGDALETALAIGRNVGLCNGKLSAMSGEEVESAEQGELAEHIGKVSVFYRTSPKHKLKIIKALQETGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDEFSAIMNAVEEGKGIFHNIKNFVRFQLSTSISALSLITLSTVCNLPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDTLRQPPRNVKDQILSRALVLRILLSATTIISGTLFIFWKEMPEDRASTPRTTTMAFTCFVFFDLFNALTCRSQTKLIFEIGFLRNRTFLYSVLGSILGQLAVIYTPPLQRVFQTESLGALDLLLLTGLASSVFILSELFKLCEKFCCRAQKAQTPQEDA", "length": 921, "header": "tr|A0A3Q1LYD6-1|A0ABI0NIV2_BOVIN Computationally mapped isoform of Calcium-transporting ATPase OS=Bos taurus OX=9913 GN=ATP2C2 PE=3 SV=2 CANONICAL=A0ABI0NIV2-1" }, "locus": { "chromosome": "18", "start_pos": 10683670, "end_pos": 10612241, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086525.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086525.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062586.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062586.2" } ] } }, { "isoform_ac": "A0A3Q1MD53-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2/entry#A0A3Q1MD53-1", "sequence": { "sequence": "MVEGRFSRLLQKLAFWGSSHKYELLAKGELETLIDGQNDLKAIEKEKTVVALEPKEASKCHREDLAKAFYVDLQNGLSEFSVTQRRLVHGWNEFVADNTEPVWKKYLDQFKNPLILLLLASALVSVLTKKYEDAISIAVAVLIVVTVAFIQEYRSEKSLEELTKLVPPECNCIREGKLQHLLARDLVPGDIVSLSIGDRVPADIRLTEVTDLLVDESSFTGEAEPSSKTDTPLTGEGDLTTLSNIVFMGTLVQCGKGQGVVIGTGEKSQFGEVFKMMQAEETPKTPLQKSMDKLGKQLTLFSFGIIGLIMFTGWLQGKHLLSMFTIGVSLAVAAIPEGLPIVVTVTLVLGVLRMARKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTVTQLVTSDGLHAEVSGVGYNGNGTVCLLPSKEVIKQFSNVSVGKLVEAGCVANNAIIRKNTVMGQPTEGALVALAMKMDLGDIKDSYIRKKEIPFSSEQKWMAVQCSSKNEEREDMYFMKGAFEEVIRYCAMYNHGGIPLPLTPQQRAFCQQEEKKMGSLGLRVLALASGPELGKLTFLGLIGIIDPPRAGVKEAVQVLSESGLSVKMITGDALETALAIGRNVGLCNGKLSAMSGEEVESAEQGELAEHIGKVSVFYRTSPKHKLKIIKALQETGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDEFSAIMNAVEEGKGIFHNIKNFVRFQLSTSISALSLITLSTVCNLPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDTLRQPPRNVKDQILSRALVLRILLSATTIISGTLFIFWKEIYAQEWDCWILSVRGLPSSIPSPVCTDFLMMGILTGGR", "length": 865, "header": "tr|A0A3Q1MD53-1|A0ABI0NIV2_BOVIN Computationally mapped isoform of Calcium-transporting ATPase OS=Bos taurus OX=9913 GN=ATP2C2 PE=3 SV=2 CANONICAL=A0ABI0NIV2-1" }, "locus": { "chromosome": "18", "start_pos": 10679389, "end_pos": 10607005, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087187.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087187.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066756.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066756.2" } ] } }, { "isoform_ac": "A0AAA9T3W6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2/entry#A0AAA9T3W6-1", "sequence": { "sequence": "MIITIDGQNDLKAIEKEKTVVALEPKEASKCHREDLAKAFYVDLQNGLSEFSVTQRRLVHGWNEFVADNTEPVWKKYLDQFKNPLILLLLASALVSVLTKKYEDAISIAVAVLIVVTVAFIQEYRSEKSLEELTKLVPPECNCIREGKLQHLLARDLVPGDIVSLSIGDRVPADIRLTEVTDLLVDESSFTGEAEPSSKTDTPLTGEGDLTTLSNIVFMGTLVQCGKGQGVVIGTGEKSQFGEVFKMMQAEETPKTPLQKSMDKLGKQLTLFSFGIIGLIMFTGWLQGKHLLSMFTIGVSLAVAAIPEGLPIVVTVTLVLGVLRMARKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTVTQLVTSDGLHAEVSGVGYNGNGTVCLLPSKEVIKQFSNVSVGKLVEAGCVANNAIIRKNTVMGQPTEGALVALAMKMDLGDIKDSYIRKKEIPFSSEQKWMAVQCSSKNEEREDMYFMKGAFEEVIRYCAMYNHGGIPLPLTPQQRAFCQQEEKKMGSLGLRVLALASGPELGKLTFLGLIGIIDPPRAGVKEAVQVLSESGLSVKMITGDALETALAIGRNVGLCNGKLSAMSGEEVESAEQGELAEHIGKVSVFYRTSPKHKLKIIKALQETGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDEFSAIMNAVEEGKGIFHNIKNFVRFQLSTSISALSLITLSTVCNLPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDTLRQPPRNVKDQILSRALVLRILLSATTIISGTLFIFWKEMPEDRASTPRTTTMAFTCFVFFDLFNALTCRSQTKLIFEIGFLRNRTFLYSVLGSILGQLAVIYTPPLQRVFQTESLGALDLLLLTGLASSVFILSELFKLCEKFCCRAQKAQTPQEDA", "length": 917, "header": "tr|A0AAA9T3W6-1|A0ABI0NIV2_BOVIN Computationally mapped isoform of Calcium-transporting ATPase OS=Bos taurus OX=9913 GN=ATP2C2 PE=3 SV=1 CANONICAL=A0ABI0NIV2-1" }, "locus": { "chromosome": "18", "start_pos": 10683670, "end_pos": 10622645, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093366.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093366.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091344.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091344.1" } ] } }, { "isoform_ac": "A0AAA9TAU7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2/entry#A0AAA9TAU7-1", "sequence": { "sequence": "MVEGRFSRLLQKLAFWGSSHKYELLAKGELETLIDGQNDLKAIEKEKTVVALEPKEASKCHREDLAKAFYFKNPLILLLLASALVSVLTKKYEDAISIAVAVLIVVTVAFIQEYRSEKSLEELTKLVPPECNCIREGKLQHLLARDLVPGDIVSLSIGDRVPADIRLTEVTDLLVDESSFTGEAEPSSKTDTPLTGEGDLTTLSNIVFMGTLVQCGKGQGVVIGTGEKSQFGEVFKMMQAEETPKTPLQKSMDKLGKQLTLFSFGIIGLIMFTGWLQGKHLLSMFTIGVSLAVAAIPEGLPIVVTVTLVLGVLRMARKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTVTQLVTSDGLHAEVSGVGYNGNGTVCLLPSKEVIKQFSNVSVGKLVEAGCVANNAIIRKNTVMGQPTEGALVALAMKMDLGDIKDSYIRKKEIPFSSEQKWMAVQCSSKNEEREDMYFMKGAFEEVIRYCAMYNHGGIPLPLTPQQRAFCQQEEKKMGSLGLRVLALASGPELGKLTFLGLIGIIDPPRAGVKEAVQVLSESGLSVKMITGDALETALAIGRNVGLCNGKLSAMSGEEVESAEQGELAEHIGKVSVFYRTSPKHKLKIIKALQETGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDEFSAIMNAVEEGKGIFHNIKNFVRFQLSTSISALSLITLSTVCNLPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDTLRQPPRNVKDQILSRALVLRILLSATTIISGTLFIFWKEMPEDRASTPRTTTMAFTCFVFFDLFNALTCRSQTKLIFEIGFLRNRTFLYSVLGSILGQLAVIYTPPLQRVFQTESLGALDLLLLTGLASSVFILSELFKLCEKFCCRAQKAQTPQEDA", "length": 907, "header": "tr|A0AAA9TAU7-1|A0ABI0NIV2_BOVIN Computationally mapped isoform of Calcium-transporting ATPase OS=Bos taurus OX=9913 GN=ATP2C2 PE=3 SV=2 CANONICAL=A0ABI0NIV2-1" }, "locus": { "chromosome": "18", "start_pos": 10683670, "end_pos": 10607005, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119544.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119544.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095121.2", "url": "https://www.ensembl.org/id/ENSBTAP00000095121.2" } ] } }, { "isoform_ac": "A0ABI0NIV2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2/entry#A0ABI0NIV2-1", "sequence": { "sequence": "MVEGRFSRLLQKLAFWGSSHKYELLAKGELETLIDGQNDLKAIEKEKTVVALEPKEASKCHREDLAKAFYVDLQNGLSEFSVTQRRLVHGWNEFVADNTEPVWKKYLDQFKNPLILLLLASALVSVLTKKYEDAISIAVAVLIVVTVAFIQEYRSEKSLEELTKLVPPECNCIREGKLQHLLARDLVPGDIVSLSIGDRVPADIRLTEVTDLLVDESSFTGEAEPSSKTDTPLTGEGDLTTLSNIVFMGTLVQCGKGQGVVIGTGEKSQFGEVFKMMQAEETPKTPLQKSMDKLGKQLTLFSFGIIGLIMFTGWLQGKHLLSMFTIGVSLAVAAIPEGLPIVVTVTLVLGVLRMARKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTVTQLVTSDGLHAEVSGVGYNGNGTVCLLPSKEVIKQFSNVSVGKLVEAGCVANNAIIRKNTVMGQPTEGALVALAMKMDLGDIKDSYIRKKEIPFSSEQKWMAVQCSSKNEEREDMYFMKGAFEEVIRYCAMYNHGGIPLPLTPQQRAFCQQEEKKMGSLGLRVLALASGPELGKLTFLGLIGIIDPPRAGVKEAVQVLSESGLSVKMITGDALETALAIGRNVGLCNGKLSAMSGEEVESAEQGELAEHIGKVSVFYRTSPKHKLKIIKALQETGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDEFSAIMNAVEEGKGIFHNIKNFVRFQLSTSISALSLITLSTVCNLPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDTLRQPPRNVKDQILSRALVLRILLSATTIISGTLFIFWKEMPEDRASTPRTTTMAFTCFVFFDLFNALTCRSQTKLIFEIGFLRNRTFLYSVLGSILGQLAVIYTPPLQRVFQTESLGALGESEGSWGLSSLPARGVKSPRGAILSPGDWARA", "length": 940, "header": "tr|A0ABI0NIV2-1|A0ABI0NIV2_BOVIN Isoform 1 of Calcium-transporting ATPase OS=Bos taurus OX=9913 GN=ATP2C2 PE=3 SV=1 CANONICAL=A0ABI0NIV2-1" }, "locus": { "chromosome": "18", "start_pos": 10682065, "end_pos": 10607005, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143532.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143532.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104178.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104178.1" } ] } }, { "isoform_ac": "F1MMF3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2/entry#F1MMF3-1", "sequence": { "sequence": "MVEGRFSRLLQKLAFWGSSHKYELLAKGELETLIDGQNDLKAIEKEKTVVALEPKEASKCHREDLAKAFYVDLQNGLSEFSVTQRRLVHGWNEFVADNTEPVWKKYLDQFKNPLILLLLASALVSVLTKKYEDAISIAVAVLIVVTVAFIQEYRSEKSLEELTKLVPPECNCIREGKLQHLLARDLVPGDIVSLSIGDRVPADIRLTEVTDLLVDESSFTGEAEPSSKTDTPLTGEGDLTTLSNIVFMGTLVQCGKGQGVVIGTGEKSQFGEVFKMMQAEETPKTPLQKSMDKLGKQLTLFSFGIIGLIMFTGWLQGKHLLSMFTIGVSLAVAAIPEGLPIVVTVTLVLGVLRMARKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTVTQLVTSDGLHAEVSGVGYNGNGTVCLLPSKEVIKQFSNVSVGKLVEAGCVANNAIIRKNTVMGQPTEGALVALAMKMDLGDIKDSYIRKKEIPFSSEQKWMAVQCSSKNEEREDMYFMKGAFEEVIRYCAMYNHGGIPLPLTPQQRAFCQQEEKKMGSLGLRVLALASGPELGKLTFLGLIGIIDPPRAGVKEAVQVLSESGLSVKMITGDALETALAIGRNVGLCNGKLSAMSGEEVESAEQGELAEHIGKVSVFYRTSPKHKLKIIKALQETGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDEFSAIMNAVEEGKGIFHNIKNFVRFQLSTSISALSLITLSTVCNLPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDTLRQPPRNVKDQILSRALVLRILLSATTIISGTLFIFWKEIYAQEWDCWILRCLRTGQAPRAPQPWPSPASCSSTSSTP", "length": 866, "header": "tr|F1MMF3-1|A0ABI0NIV2_BOVIN Computationally mapped isoform of Calcium-transporting ATPase OS=Bos taurus OX=9913 GN=ATP2C2 PE=3 SV=4 CANONICAL=A0ABI0NIV2-1" }, "locus": { "chromosome": "18", "start_pos": 10681720, "end_pos": 10607005, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061207.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061207.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053487.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053487.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:510329", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510329", "resource": "KEGG Pathway" }, { "id": "R-BTA-936837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "P-type calcium transporter activity", "id": "GO:0005388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005388", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "P-type manganese transporter activity", "id": "GO:0140613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140613", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" }, { "name": "manganese ion transport", "id": "GO:0006828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006828", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18105", "name": "", "equation": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "D3K0R6-1", "P57709-1", "F1N7J2-1", "Q0VCY0-1", "A0AAA9TEJ1-1", "A0ABI0NIV2-1", "E1BMQ6-1", "A0AAA9T933-1" ], "evidence": [ { "id": "18105", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18105" } ] }, { "id": "66820", "name": "", "equation": "Mn(2+)(in) + ATP + H2O = Mn(2+)(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P57709-1", "A0ABI0NIV2-1" ], "evidence": [ { "id": "66820", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66820" } ] }, { "id": "R-BTA-936883", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-167012" ], "enzyme_list": [ "A0ABI0NIV2-1", "P57709-1" ], "evidence": [ { "id": "R-BTA-936883", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936883" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-167012", "participant_name": "Ca2+ [Golgi lumen]", "crossref": [ { "id": "C00076", "database": "COMPOUND", "url": "" }, { "id": "29108", "database": "ChEBI", "url": "" }, { "id": "HMDB0000464", "database": "HMDB Metabolite", "url": "" }, { "id": "8145461", "database": "PubChem Substance", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9T933", "gene_name": "ATP2A2", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9T933", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T933" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "A0AAA9T933", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T933" } ] } ] }, { "uniprot_ac": "A0AAA9TEJ1", "gene_name": "ATP2B2", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TEJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEJ1" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "A0AAA9TEJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEJ1" } ] } ] }, { "uniprot_ac": "A0ABI0NIV2", "gene_name": "ATP2C2", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "A0ABI0NIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" } ] } ] }, { "uniprot_ac": "D3K0R6", "gene_name": "ATP2B4", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "D3K0R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/D3K0R6" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "D3K0R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/D3K0R6" } ] } ] }, { "uniprot_ac": "E1BMQ6", "gene_name": "ATP2A3", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "E1BMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMQ6" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "E1BMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMQ6" } ] } ] }, { "uniprot_ac": "F1N7J2", "gene_name": "ATP2B1", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "F1N7J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7J2" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "F1N7J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7J2" } ] } ] }, { "uniprot_ac": "P57709", "gene_name": "ATP2C1", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "P57709", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P57709" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "P57709", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P57709" } ] } ] }, { "uniprot_ac": "Q0VCY0", "gene_name": "ATP2A1", "activity": [ { "ec_number": "7.2.2.10", "activity": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VCY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCY0" } ] }, { "ec_number": "7.2.2.10", "activity": "", "evidence": [ { "id": "Q0VCY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCY0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIV2" }, { "id": "SM00831", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00831" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cation-transporting P-type ATPase N-terminal", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 130, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "7.2.2.10", "ec_name": "Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "7.2.2.10", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.10" }, { "id": "7.2.2.10", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=7.2.2.10" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 412, "end_pos": 414 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 872, "end_pos": 874 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNP8-1", "uniprot_ac": "E1BNP8", "uniprot_id": "E1BNP8_BOVIN", "mass": { "chemical_mass": 119932.0, "monoisotopic_mass": 119932.0 }, "refseq": { "ac": "NP_001179321", "name": "FACT complex subunit SPT16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179321" }, "gene_names": [ { "name": "SUPT16H", "type": "recommended", "evidence": [ { "id": "E1BNP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" } ] }, { "name": "SUPT16H", "type": "synonym", "evidence": [ { "id": "NP_001179321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179321" } ] } ], "protein_names": [ { "name": "FACT complex subunit", "type": "recommended", "evidence": [ { "id": "E1BNP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNP8/entry#names_and_taxonomy" } ] }, { "name": "FACT complex subunit SPT16", "type": "synonym", "evidence": [ { "id": "NP_001179321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179321" } ] }, { "name": "suppressor of Ty 16 homolog", "type": "synonym", "evidence": [ { "id": "NP_001179321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179321" } ] } ], "function": [ { "annotation": "Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II).", "evidence": [ { "database": "UniProtKB", "id": "E1BNP8", "url": "https://www.uniprot.org/uniprotkb/E1BNP8#function" }, { "database": "UniProtKB", "id": "ARBA00053946", "url": "https://www.uniprot.org/uniprotkb/ARBA00053946#function" }, { "database": "UniProtKB", "id": "A0AAA9T403", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T403#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNP8", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SUPT16H", "url": "https://www.uniprot.org/uniprotkb/E1BNP8", "locus": { "chromosome": "10", "start_pos": 25806673, "end_pos": 25771307, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020421", "url": "https://www.ensembl.org/id/ENSBTAG00000020421" } ] } } ], "crossref": [ { "id": "E1BNP8", "url": "https://alphafold.ebi.ac.uk/entry/E1BNP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020421", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020421", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01091", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01091", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514989", "url": "https://www.ncbi.nlm.nih.gov/gene/514989", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514989", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514989", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHINTIP", "url": "https://omabrowser.org/oma/group/YHINTIP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNP8", "url": "https://www.orthodb.org/?gene=E1BNP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13980", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13980", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13980:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13980:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08512", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08512", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24824", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24824", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6796648", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6796648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6804756", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179321", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179321", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T403", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T403", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T403-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T403-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNP8", "url": "https://www.uniprot.org/uniprotkb/E1BNP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNP8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVTLDKDAYYRRVKRLYSNWRKGEDEYANVDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLVREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLNKEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEEGDSESEIEDETFNPSEEDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK", "length": 1047, "header": "tr|E1BNP8-1|E1BNP8_BOVIN Isoform 1 of FACT complex subunit OS=Bos taurus OX=9913 GN=SUPT16H PE=3 SV=2 CANONICAL=E1BNP8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T403-1", "url": "https://www.uniprot.org/uniprotkb/E1BNP8/entry#A0AAA9T403-1", "sequence": { "sequence": "MGGAIAPARGSLCGAGPARQDSRLSVQSPPPRQGIGAPGDLGPGESKGGGRASRDDVDSRAAVAKLTRKPRETLDSFCVARFVAFPPLPSSPPRNLRRKDFFKKEFRSLPGPGSGKGIFEVDTSGSLGECGIPGPREGGGAGTSRDSRNPRRSGVCGYGCNSRQRRLLSTSEETVQQLEEPECCAPGPARITTISSRMDGGARRMRIGLLAFTICVALAGVKKRHTAHAQPPPVLGLPWVTQKSNAENLQVLKGEDEYANVDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLVREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLNKEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEEGDSESEIEDETFNPSEEDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK", "length": 1277, "header": "tr|A0AAA9T403-1|E1BNP8_BOVIN Computationally mapped isoform of FACT complex subunit OS=Bos taurus OX=9913 GN=SUPT16H PE=3 SV=1 CANONICAL=E1BNP8-1" }, "locus": { "chromosome": "10", "start_pos": 25806004, "end_pos": 25771506, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132215.2", "url": "https://www.ensembl.org/id/ENSBTAT00000132215.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092520.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092520.1" } ] } }, { "isoform_ac": "E1BNP8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNP8/entry#E1BNP8-1", "sequence": { "sequence": "MAVTLDKDAYYRRVKRLYSNWRKGEDEYANVDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLVREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLNKEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEEGDSESEIEDETFNPSEEDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK", "length": 1047, "header": "tr|E1BNP8-1|E1BNP8_BOVIN Isoform 1 of FACT complex subunit OS=Bos taurus OX=9913 GN=SUPT16H PE=3 SV=2 CANONICAL=E1BNP8-1" }, "locus": { "chromosome": "10", "start_pos": 25806004, "end_pos": 25771978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027214.8", "url": "https://www.ensembl.org/id/ENSBTAT00000027214.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027214.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027214.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514989", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514989", "resource": "KEGG Pathway" }, { "id": "R-BTA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-BTA-6796648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6796648", "resource": "Reactome", "description": "TP53 Regulates Transcription of DNA Repair Genes" }, { "id": "R-BTA-6804756", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "resource": "Reactome", "description": "Regulation of TP53 Activity through Phosphorylation" }, { "id": "R-BTA-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" }, { "id": "R-BTA-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M120-1", "protein_name": "FACT complex subunit", "gene_name": "Supt16h", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVTLDKDAYYRRVKRLYSNWRKGEDEYASIDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWSDCLNKEGFDKVDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPTQEVQENYNFLLQLQEELLKELRHGVKICDVYNSVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEDKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEDGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK", "length": 1047 }, "evidence": [ { "id": "E1BNP8", "url": "https://omabrowser.org/oma/group/E1BNP8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1S8K5-1", "protein_name": "FACT complex subunit", "gene_name": "SUPT16H", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPGHWESAGFRGRERVAEPGPRVILGTRGGAASVAMAVTLDKDAYYRRVKRLYSNWRKGEDEYANVDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLNKEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEEGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK", "length": 1083 }, "evidence": [ { "id": "E1BNP8", "url": "https://omabrowser.org/oma/group/E1BNP8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P32558-1", "protein_name": "FACT complex subunit SPT16", "gene_name": "SPT16", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEELNIDFDVFKKRIELLYSKYNEFEGSPNSLLFVLGSSNAENPYQKTTILHNWLLSYEFPATLIALVPGKVIIITSSAKAKHLQKAIDLFKDPESKITLELWQRNNKEPELNKKLFDDVIALINSAGKTVGIPEKDSYQGKFMTEWNPVWEAAVKENEFNVIDISLGLSKVWEVKDVNEQAFLSVSSKGSDKFMDLLSNEMVRAVDEELKITNAKLSDKIENKIDDVKFLKQLSPDLSALCPPNYKFNFDLLDWTYSPIIQSGKKFDLRVSARSTNDQLYGNGCILASCGIRYNNYCSNITRTFLIDPSEEMANNYDFLLTLQKEIVTNILKPGRTPKEVYESVIEYIEKTKPELVPNFTKNIGSLIGLEFRDSNFILNVKNDYRKIQRGDCFNISFGFNNLKDSQSANNYALQLADTVQIPLDETEPPRFLTNYTKAKSQISFYFNNEEEDNNKKKSSPATKVPSKPDRNSKILRTKLRGEARGGAEDAQKEQIRKENQKKLHEKLEKNGLLRFSAADANGPDSEPRQYFKKYESYVRDSQLPTNIRDLRIHVDWKSQTIILPIYGRPVPFHINSYKNGSKNEEGEYTYLRLNFNSPGSSGGISKKVEELPYEESADNQFVRSITLRSKDGDRMSETFKQIADLKKEATKREQERKALADVVQQDKLIENKTGRTKRLDQIFVRPNPDTKRVPSTVFIHENGIRFQSPLRTDSRIDILFSNIKNLIFQSCKGELIVVIHIHLKNPILMGKKKIQDVQFYREASDMSVDETGGGRRGQSRFRRYGDEDELEQEQEERRKRAALDKEFKYFADAIAEASNGLLTVENTFRDLGFQGVPNRSAVFCMPTTDCLVQLIEPPFLVINLEEVEICILERVQFGLKNFDMVFVYKDFNKPVTHINTVPIESLDFLKQWLTDMDIPYTVSTINLNWATIMKSLQDDPYQFFLDGGWNFLATGSDDEASDESEEEVSEYEASEDDVSDESAFSEDEEGSEVDDDISGDESEDYTGDESEEGEDWDELEKKAARADRGANFRD", "length": 1035 }, "evidence": [ { "id": "E1BNP8", "url": "https://omabrowser.org/oma/group/E1BNP8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54S43-1", "protein_name": "FACT complex subunit SPT16", "gene_name": "spt16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQSTTTTTTTTAAPAVPTGPREATLDAGNFCKRVKILYDSWNSDSNLWKSANSLVLALGQPNESNPYQKVTSLQTWLFGYELKDTIIVFLEKEIYIVSTSKKINLFQKLSETEQVKTELSSIKFNFLTIDKSDKNKSNFEKLIGEATKAGSNIGVIIKETYIGDLALQWEAALNECPLTKVDITPALSSCLLVKDLQEQKNIITSAKITSKVLKSHILPKIETIIDKGERQTHNQLADYAADIFESPEKISSKLTVEHVDYSYVPIIQSGGIYDLRASASSDDNPLHFGTIIVSCGARYKNYCSNIARTYIIDPTSDQKKNYAILLNVQSNVIKAIKPDVTFSSLYEKAIQTIKESSKPELVDHFPKNVGYGIGIEFQESLAVLNATNSRTLKAGMTLNIACGFQKISNPEGKDEKSKTYSLLISDTVLLNDEGKVEVLTDVGKKASDVVYMLGGEDDDDDNDNDPSVKLELPDDVKGITGRTIETKEKSKSVEERRRDHQKMLEQKNLQEAENKIKAMTDPNGKKGTPEVDYTAITKLQPIYSSVGAYPQDIVKNKMYIDPKKETVLFPIFGYMVPFHISTIKNISKSEEYIRVNFNTPTSYTQEQIDAGFVPPQLMYIREVTYKVNDPKVLANNIRLIKELKKKFTTRETEDREKRNLITQEKLILLRGKFPRLPEVHARPTLSGARRTIGILEAHENGIRFNPTSTKDRTPIDVLYKNIKHAIYQQADQESMAVIHFHLHDALMIGKKKTKDVQFYIEISEMSQSLDVSSRFNDEEEEERRERALKEKINNDFKTFIKRVEEIAPEPGLEFDVPYRELGFYGVPNVSTVFIQPSVHCLLSILEPPFFVLTLDDVEIACFERAIRSLKNFDLSFVFKDYNRPPIRISVIPRNYFETVKEWLDSFNIKFYQSERNYNWKRIMDTIKSDVKKFHDDGGWSFLDLEEEEEEEDSGDDDYHSNSDESESSDYISSMSSGSDDDDEDSSEGENWEDLEQKAERDDKMKTFDETNKRKRDEKSVSSSNRPSSSKSGSSSSGGGGGGGGSSRSKSSSSSSKGSSSSSSKSSSSKRK", "length": 1072 }, "evidence": [ { "id": "E1BNP8", "url": "https://omabrowser.org/oma/group/E1BNP8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IRG6-1", "protein_name": "FACT complex subunit spt16", "gene_name": "dre4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSFVLDKEAFVRRVKRLYTEWRAPSIGHDDALRNLDCIMSIVGVEEDVMYSKSMALQLWLLGYELTDTISVFCSDAVYFLTSKKKIEFLKQTQNITEEGFPEINLLVRDRTDKDQGNFEKLIKALQNSKKGKRLGVFAKDAYPGEFSEAWKKSLTASKFEHVDISTIIAYLMCPKDESEINNIRKASLVSMDIFNKYLKDEIMDIIDSDRKVKHNKLSDGCEAAIGEKKYTSGLDPRLLDMAYPPIIQSGGAYSLKFSAVADKNPLHFGVIVCSLGARYKSYCSNISRTFLVNPTEAMQENYTFLVSVQEEILKLLVPGTKLCDVYEKTLDFVKKEKPSMVDNLPKSFGFAMGLEFRENSIVIGPKCQALLKKNMVFNLHVGISNLTNPEATDKEGKNYALFIGDTVLVGEQSPASVMTPSKKKIKNVGIFIKDDSDEEDVDDKKTAKEDQGTEILGRSKRNAVLESKLRNEINTEEKRKEHQRELAQQLNERAKDRLARQGNSKEVEKVRKNTVSYKSISQMPREPEVKELKLYVDKKYETVIMPVFGIQVPFHISTIKNISQSVEGEYTYLRINFFHPGATMGRNEGGLYPQPEATFVKEVTYRSSNVKEHGEVGAPSANLNNAFRLIKEVQKRFKTREAEEREKEDLVKQDTLILSQNKGNPKLKDLYIRPNIVTKRMTGSLEAHSNGFRYISVRGDKVDILYNNIKSAFFQPCDGEMIILLHFHLKYAIMFGKKKHVDVQFYTEVGEITTDLGKHQHMHDRDDLAAEQAERELRHKLKTAFKSFCEKVETMTKSVVEFDTPFRELGFPGAPFRSTVTLQPTSGSLVNLTEWPPFVITLDDVELVHFERVQFHLRNFDMIFVFKEYNKKVAMVNAIPMNMLDHVKEWLNSCDIRYSEGVQSLNWQKIMKTITDDPEGFFEQGGWTFLDPESGSEGENETAESEEDEAYNPTDAESDEESDEDSEYSEASEDSEESDEDLGSDEESGKDWSDLEREAAEEDRNHDYAADDKPRNGKFDSKKHGKSSKHSPSKSSKDKYNSRDKHHSSSSSGNKSSSKDKDRKRSRDDSRDNGHKSKKSRH", "length": 1083 }, "evidence": [ { "id": "E1BNP8", "url": "https://omabrowser.org/oma/group/E1BNP8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q920B9-1", "protein_name": "FACT complex subunit SPT16", "gene_name": "Supt16h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVTLDKDAYYRRVKRLYSNWRKGEDEYASIDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLVREKNESNKSSFDKMIDAIKESKSGKKIGVFSKDKFPGEFMKSWSDCLNKEGFDKVDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPTQEVQENYNFLLQLQEELLKELRHGVKICDVYNSVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATILTSVKKKVKNVGIFLKNEDDEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAVMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEDGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK", "length": 1047 }, "evidence": [ { "id": "E1BNP8", "url": "https://omabrowser.org/oma/group/E1BNP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5B9-1", "protein_name": "FACT complex subunit SPT16", "gene_name": "SUPT16H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVTLDKDAYYRRVKRLYSNWRKGEDEYANVDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLNKEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNIKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEEGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK", "length": 1047 }, "evidence": [ { "id": "E1BNP8", "url": "https://omabrowser.org/oma/group/E1BNP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "E1BNP8", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BNP8", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "E1BNP8", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "E1BNP8", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription, elongation", "id": "GO:0032786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032786", "evidence": [ { "database": "UniProtKB", "id": "E1BNP8", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription elongation", "id": "GO:0032784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032784", "evidence": [ { "database": "UniProtKB", "id": "E1BNP8", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "FACT complex", "id": "GO:0035101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035101", "evidence": [ { "database": "UniProtKB", "id": "E1BNP8", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "E1BNP8", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" }, { "start_pos": 901, "end_pos": 903, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNP8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1047, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNP8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNP8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" }, { "id": "SM01285", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01285" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FACT complex subunit SPT16 N-terminal lobe", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 168, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" }, { "id": "SM01286", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01286" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FACT complex subunit SPT16 middle", "eco_id": "ECO_0000259", "start_pos": 529, "end_pos": 689, "start_aa": "Ile", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNP8" }, { "id": "SM01287", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone chaperone RTT106/FACT complex subunit SPT16-like middle", "eco_id": "ECO_0000259", "start_pos": 806, "end_pos": 896, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 114, "end_pos": 116 }, { "start_pos": 509, "end_pos": 511 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 656, "end_pos": 658 }, { "start_pos": 826, "end_pos": 828 }, { "start_pos": 901, "end_pos": 903 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLX3-1", "uniprot_ac": "E1BLX3", "uniprot_id": "E1BLX3_BOVIN", "mass": { "chemical_mass": 31018.0, "monoisotopic_mass": 31018.0 }, "refseq": { "ac": "NP_001180131", "name": "protein orai-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180131" }, "gene_names": [ { "name": "ORAI3", "type": "recommended", "evidence": [ { "id": "E1BLX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLX3" } ] }, { "name": "ORAI3", "type": "synonym", "evidence": [ { "id": "NP_001180131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180131" } ] } ], "protein_names": [ { "name": "ORAI calcium release-activated calcium modulator 3", "type": "synonym", "evidence": [ { "id": "E1BLX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLX3/entry#names_and_taxonomy" } ] }, { "name": "protein orai-3", "type": "synonym", "evidence": [ { "id": "NP_001180131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180131" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLX3", "url": "https://www.uniprot.org/uniprotkb/E1BLX3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ORAI3", "url": "https://www.uniprot.org/uniprotkb/E1BLX3", "locus": { "chromosome": "25", "start_pos": 27092739, "end_pos": 27087694, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002344", "url": "https://www.ensembl.org/id/ENSBTAG00000002344" } ] } } ], "crossref": [ { "id": "E1BLX3", "url": "https://alphafold.ebi.ac.uk/entry/E1BLX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002344", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002344", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515971", "url": "https://www.ncbi.nlm.nih.gov/gene/515971", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012446", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012446", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515971", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515971", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DFVHRGY", "url": "https://omabrowser.org/oma/group/DFVHRGY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BLX3", "url": "https://www.orthodb.org/?gene=E1BLX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31501:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31501:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180131", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180131", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TKB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKB5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLX3", "url": "https://www.uniprot.org/uniprotkb/E1BLX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLX3-1", "url": "https://www.uniprot.org/uniprotkb/E1BLX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGGEGDPGEQAPLNPEAESPAGSATYREFVHRGYLDLMGASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLESKHEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPLGTSGSVGPASQLPTVATSLSPASKPSSVSVAPSQAEPPEPCPPRQACGSGAAHGPGWQAAMASTAIMVPVGLVFVAFALHFYRSLVAHKTDRHKQELEELSRLQGELQAV", "length": 291, "header": "tr|E1BLX3-1|E1BLX3_BOVIN Isoform 1 of ORAI calcium release-activated calcium modulator 3 OS=Bos taurus OX=9913 GN=ORAI3 PE=3 SV=1 CANONICAL=E1BLX3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TKB5-1", "url": "https://www.uniprot.org/uniprotkb/E1BLX3/entry#A0AAA9TKB5-1", "sequence": { "sequence": "MFASWLGLWCASLQTPALDFSVNSNNNSKHLLEHTMYLTLFLSLDVSLNVSLNFHNNPIRQVAMVEVQLESKHEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPLGTSGSVGPASQLPTVATSLSPASKPSSVSVAPSQAEPPEPCPPRQACGSGAAHGPGWQAAMASTAIMVPVGLVFVAFALHFYRSLVAHKTDRHKQELEELSRLQGELQAV", "length": 276, "header": "tr|A0AAA9TKB5-1|E1BLX3_BOVIN Computationally mapped isoform of ORAI calcium release-activated calcium modulator 3 OS=Bos taurus OX=9913 GN=ORAI3 PE=3 SV=1 CANONICAL=E1BLX3-1" }, "locus": { "chromosome": "25", "start_pos": 27091908, "end_pos": 27090438, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091198.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091198.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096702.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096702.1" } ] } }, { "isoform_ac": "E1BLX3-1", "url": "https://www.uniprot.org/uniprotkb/E1BLX3/entry#E1BLX3-1", "sequence": { "sequence": "MKGGEGDPGEQAPLNPEAESPAGSATYREFVHRGYLDLMGASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLESKHEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPLGTSGSVGPASQLPTVATSLSPASKPSSVSVAPSQAEPPEPCPPRQACGSGAAHGPGWQAAMASTAIMVPVGLVFVAFALHFYRSLVAHKTDRHKQELEELSRLQGELQAV", "length": 291, "header": "tr|E1BLX3-1|E1BLX3_BOVIN Isoform 1 of ORAI calcium release-activated calcium modulator 3 OS=Bos taurus OX=9913 GN=ORAI3 PE=3 SV=1 CANONICAL=E1BLX3-1" }, "locus": { "chromosome": "25", "start_pos": 27091908, "end_pos": 27087902, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003026.5", "url": "https://www.ensembl.org/id/ENSBTAT00000003026.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003026.3", "url": "https://www.ensembl.org/id/ENSBTAP00000003026.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515971", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515971", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I7X5-1", "protein_name": "Protein orai-3", "gene_name": "Orai3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKGGEGDTGEQAPLNPGADSPAGSATYREFVHRGYLDLMGASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLESGHEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPMNKPAPVVPMSQVPPVTVSLSLASNLTPSSASIATSQQPSKACPPRQVCGGAHGPGWQAAMASTAIMVPVGLVFMAFALHFYRSLVAHKTDRHKQELEELSRLQGELQAV", "length": 290 }, "evidence": [ { "id": "E1BLX3", "url": "https://omabrowser.org/oma/group/E1BLX3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A4X1TL02-1", "protein_name": "ORAI calcium release-activated calcium modulator 3", "gene_name": "ORAI3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKGGEGDAGEQAPLNPEAESPAGSATYREFVHRGYLDLMGASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLESKYEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPSGTSAPMVPASQVPGTLPPVATALSPASKPSSASVAPSQAEPPEACPPRQVCGGGGGGGGHGPGWQAAMASTAIMVPVGLVFVVFALHFYRSLVAHKTDRHKQELEELSRLQGELQAV", "length": 298 }, "evidence": [ { "id": "E1BLX3", "url": "https://omabrowser.org/oma/group/E1BLX3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6P8G8-1", "protein_name": "Protein orai-3", "gene_name": "Orai3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGGEGDTGEQAPLNPEVDSPAGSATYREFVHRGYLDLMGASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLENDHEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPMGKPAPVVPMSQVPPVTVSLSLASNLTPSSASITTSQQPSKACPPRQVCDSAHGPGWQAAMASTAIMVPVGLVFMAFALHFYRSLVAHKTDRHKQELEELSRLQGELQAV", "length": 290 }, "evidence": [ { "id": "E1BLX3", "url": "https://omabrowser.org/oma/group/E1BLX3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BRQ5-1", "protein_name": "Protein orai-3", "gene_name": "ORAI3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGGEGDAGEQAPLNPEGESPAGSATYREFVHRGYLDLMGASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLESDHEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPLDTPTPMVPTSRVPGTLAPVATSLSPASNLPRSSASAAPSQAEPACPPRQACGGGGAHGPGWQAAMASTAIMVPVGLVFVAFALHFYRSLVAHKTDRYKQELEELNRLQGELQAV", "length": 295 }, "evidence": [ { "id": "E1BLX3", "url": "https://omabrowser.org/oma/group/E1BLX3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BLX3", "url": "https://www.uniprot.org/uniprotkb/E1BLX3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BLX3", "url": "https://www.uniprot.org/uniprotkb/E1BLX3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "store-operated calcium entry", "id": "GO:0002115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002115", "evidence": [ { "database": "UniProtKB", "id": "E1BLX3", "url": "https://www.uniprot.org/uniprotkb/E1BLX3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "store-operated calcium channel activity", "id": "GO:0015279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015279", "evidence": [ { "database": "UniProtKB", "id": "E1BLX3", "url": "https://www.uniprot.org/uniprotkb/E1BLX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MPF0-1", "A0AAA9RSQ6-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLX3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 291, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLX3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLX3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NKF2-1", "uniprot_ac": "A0ABI0NKF2", "uniprot_id": "A0ABI0NKF2_BOVIN", "mass": { "chemical_mass": 51193.0, "monoisotopic_mass": 51193.0 }, "refseq": {}, "gene_names": [ { "name": "IKBKG", "type": "recommended", "evidence": [ { "id": "A0ABI0NKF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKF2" } ] } ], "protein_names": [ { "name": "NF-kappa-B essential modulator", "type": "recommended", "evidence": [ { "id": "A0ABI0NKF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKF2/entry#names_and_taxonomy" } ] }, { "name": "IkB kinase-associated protein 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NKF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKF2/entry#names_and_taxonomy" } ] }, { "name": "Inhibitor of nuclear factor kappa-B kinase subunit gamma", "type": "synonym", "evidence": [ { "id": "A0ABI0NKF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKF2/entry#names_and_taxonomy" } ] }, { "name": "NF-kappa-B essential modifier", "type": "synonym", "evidence": [ { "id": "A0ABI0NKF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKF2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin plays a key role in IKK activation by multiple signaling receptor pathways. Can recognize and bind both 'Lys-63'-linked and linear polyubiquitin upon cell stimulation, with a much higher affinity for linear polyubiquitin. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. 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"https://www.uniprot.org/uniprotkb/A0ABI0NKF2", "locus": { "chromosome": "X", "start_pos": 37604668, "end_pos": 37587308, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006268", "url": "https://www.ensembl.org/id/ENSBTAG00000006268" } ] } } ], "crossref": [ { "id": "cd09803", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09803", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR021063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032419", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032419", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051301", "database": "InterPro", 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"MTLLGRRHFLFIICAFQALTCWMSRPPWKSPLCEMVQPSGSPAGDQDMLGEESSLGKPAMLHVPSEQGTPETFQRCLEENQELRDAIRQSNQMLRERCEELQHFQGNQREEKAFLMQKFQEARDLVVRLSLEKRELRQQREQALKEVERLKTCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQALESRARVASEKARQLESEREALEQRHSVQVDQLVLQNESMEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHMKSSMVSSERNRGLQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKEFLQEQLEQLQREYSRLKTSCQESARIEDMRKRHVEVSQPPLAPGPAHHSFHLNPSSQRRSPPDEPPKFCCPKCQYQAPDIDTLQIHVMECIE", "length": 441, "header": "tr|A0ABI0NKF2-1|A0ABI0NKF2_BOVIN Isoform 1 of NF-kappa-B essential modulator OS=Bos taurus OX=9913 GN=IKBKG PE=4 SV=1 CANONICAL=A0ABI0NKF2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TPF0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKF2/entry#A0AAA9TPF0-1", "sequence": { "sequence": "MSRPPWKSPLCEMVQPSGSPAGDQDMLGEESSLGKPAMLHVPSEQGTPETFQRCLEENQELRAISADAIRQSNQMLRERCEELQHFQGNQREEKAFLMQKFQEARDLVVRLSLEKRELRQQREQALKEVERLKTCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQALESRARVASEKARQLESEREALEQRHSVQVDQLVLQNESMEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHMKSSMVSSERNRGLQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKEFLQEQLEQLQREYSRLKTSCQESARIEDMRKRHVEVSQPPLAPGPAHHSFHLNPSSQRRSPPDEPPKFCCPKCQYQAPDIDTLQIHVMECIE", "length": 423, "header": "tr|A0AAA9TPF0-1|A0ABI0NKF2_BOVIN Computationally mapped isoform of NF-kappa-B essential modulator OS=Bos taurus OX=9913 GN=IKBKG PE=4 SV=2 CANONICAL=A0ABI0NKF2-1" }, "locus": { "chromosome": "X", "start_pos": 37603902, "end_pos": 37591147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099112.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099112.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099147.2", "url": "https://www.ensembl.org/id/ENSBTAP00000099147.2" } ] } }, { "isoform_ac": 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Peptide", "id": "ENSBTAP00000008224.5", "url": "https://www.ensembl.org/id/ENSBTAP00000008224.5" } ] } }, { "isoform_ac": "A0ABI0NKF2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKF2/entry#A0ABI0NKF2-1", "sequence": { "sequence": "MTLLGRRHFLFIICAFQALTCWMSRPPWKSPLCEMVQPSGSPAGDQDMLGEESSLGKPAMLHVPSEQGTPETFQRCLEENQELRDAIRQSNQMLRERCEELQHFQGNQREEKAFLMQKFQEARDLVVRLSLEKRELRQQREQALKEVERLKTCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQALESRARVASEKARQLESEREALEQRHSVQVDQLVLQNESMEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHMKSSMVSSERNRGLQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKEFLQEQLEQLQREYSRLKTSCQESARIEDMRKRHVEVSQPPLAPGPAHHSFHLNPSSQRRSPPDEPPKFCCPKCQYQAPDIDTLQIHVMECIE", "length": 441, "header": "tr|A0ABI0NKF2-1|A0ABI0NKF2_BOVIN Isoform 1 of NF-kappa-B essential modulator OS=Bos taurus OX=9913 GN=IKBKG PE=4 SV=1 CANONICAL=A0ABI0NKF2-1" }, "locus": { "chromosome": "X", "start_pos": 37603902, "end_pos": 37587950, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": 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411, "end_pos": 441, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179548", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179548", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RTF1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTF1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXB1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXB1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TY66", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TY66-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNK5", "url": "https://www.uniprot.org/uniprotkb/E1BNK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNK5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLLGPLCLLLSSAADSQLLPGNNFTNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPTFFPCASGVHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCKNGLCIDKSFICDGQNNCQDNSDEESCESSQEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHRCNVTYNVNNGIQYVASQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSADSASSQAASSLLSVDDTSHSPGQPGPQEGTAEPRDSAPSQGTEDV", "length": 345, "header": "tr|E1BNK5-1|E1BNK5_BOVIN Isoform 1 of Low-density lipoprotein receptor class A domain-containing protein 3 OS=Bos taurus OX=9913 GN=LDLRAD3 PE=3 SV=3 CANONICAL=E1BNK5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RTF1-1", "url": "https://www.uniprot.org/uniprotkb/E1BNK5/entry#A0AAA9RTF1-1", "sequence": { "sequence": "MGEGRSDSQLLPGNNFTNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPTFFPCASGVHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCKNGLCIDKSFICDGQNNCQDNSDEESCESSQEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHRCNVTYNVNNGIQYVASQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSADSASSQAASSLLSVDDTSHSPGQPGPQEGTAEPRDSAPSQGTEDV", "length": 336, "header": "tr|A0AAA9RTF1-1|E1BNK5_BOVIN Computationally mapped isoform of Low-density lipoprotein receptor class A domain-containing protein 3 OS=Bos taurus OX=9913 GN=LDLRAD3 PE=3 SV=1 CANONICAL=E1BNK5-1" }, "locus": { "chromosome": "15", "start_pos": 66700369, "end_pos": 66502565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102655.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102655.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075153.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075153.1" } ] } }, { "isoform_ac": "A0AAA9RXB1-1", "url": "https://www.uniprot.org/uniprotkb/E1BNK5/entry#A0AAA9RXB1-1", "sequence": { "sequence": "MTSLRQSKKSVSVCCVLSTSEGLFSYSQLLPGNNFTNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPTFFPCASGVHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCKNGLCIDKSFICDGQNNCQDNSDEESCESSQEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHRCNVTYNVNNGIQYVASQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSADSASSQAASSLLSVDDTSHSPGQPGPQEGTAEPRDSAPSQGTEDV", "length": 355, "header": "tr|A0AAA9RXB1-1|E1BNK5_BOVIN Computationally mapped isoform of Low-density lipoprotein receptor class A domain-containing protein 3 OS=Bos taurus OX=9913 GN=LDLRAD3 PE=3 SV=1 CANONICAL=E1BNK5-1" }, "locus": { "chromosome": "15", "start_pos": 66700369, "end_pos": 66513955, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132549.2", "url": "https://www.ensembl.org/id/ENSBTAT00000132549.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075831.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075831.1" } ] } }, { "isoform_ac": "A0AAA9TY66-1", "url": "https://www.uniprot.org/uniprotkb/E1BNK5/entry#A0AAA9TY66-1", "sequence": { "sequence": "MWLLGPLCLLLSSAAAKAKSKCGPTFFPCASGVHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCKNGLCIDKSFICDGQNNCQDNSDEESCESSQEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHRCNVTYNVNNGIQYVASQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSADSASSQAASSLLSVDDTSHSPGQPGPQEGTAEPRDSAPSQGTEDV", "length": 296, "header": "tr|A0AAA9TY66-1|E1BNK5_BOVIN Computationally mapped isoform of Low-density lipoprotein receptor class A domain-containing protein 3 OS=Bos taurus OX=9913 GN=LDLRAD3 PE=3 SV=1 CANONICAL=E1BNK5-1" }, "locus": { "chromosome": "15", "start_pos": 66700369, "end_pos": 66431232, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119130.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119130.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101606.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101606.1" } ] } }, { "isoform_ac": "E1BNK5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNK5/entry#E1BNK5-1", "sequence": { "sequence": "MWLLGPLCLLLSSAADSQLLPGNNFTNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPTFFPCASGVHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCKNGLCIDKSFICDGQNNCQDNSDEESCESSQEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHRCNVTYNVNNGIQYVASQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSADSASSQAASSLLSVDDTSHSPGQPGPQEGTAEPRDSAPSQGTEDV", "length": 345, "header": "tr|E1BNK5-1|E1BNK5_BOVIN Isoform 1 of Low-density lipoprotein receptor class A domain-containing protein 3 OS=Bos taurus OX=9913 GN=LDLRAD3 PE=3 SV=3 CANONICAL=E1BNK5-1" }, "locus": { "chromosome": "15", "start_pos": 66700369, "end_pos": 66431232, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061639.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061639.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053502.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053502.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:525908", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525908", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BNK5", "url": "https://www.uniprot.org/uniprotkb/E1BNK5" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "E1BNK5", "url": "https://www.uniprot.org/uniprotkb/E1BNK5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BNK5", "url": "https://www.uniprot.org/uniprotkb/E1BNK5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "E1BNK5", "url": "https://www.uniprot.org/uniprotkb/E1BNK5" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "E1BNK5", "url": "https://www.uniprot.org/uniprotkb/E1BNK5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "E1BNK5", "url": "https://www.uniprot.org/uniprotkb/E1BNK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 24, "end_pos": 26 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLK4-1", "uniprot_ac": "E1BLK4", "uniprot_id": "E1BLK4_BOVIN", "mass": { "chemical_mass": 28152.0, "monoisotopic_mass": 28152.0 }, "refseq": { "ac": "NP_001192817", "name": "voltage-dependent calcium channel gamma-6 subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192817" }, "gene_names": [ { "name": "CACNG6", "type": "recommended", "evidence": [ { "id": "E1BLK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLK4" } ] }, { "name": "CACNG6", "type": "synonym", "evidence": [ { "id": "NP_001192817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192817" } ] } ], "protein_names": [ { "name": "Voltage-dependent calcium channel gamma-6 subunit", "type": "recommended", "evidence": [ { "id": "E1BLK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLK4/entry#names_and_taxonomy" } ] }, { "name": "voltage-dependent calcium channel gamma-6 subunit", "type": "synonym", "evidence": [ { "id": "NP_001192817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192817" } ] } ], "function": [ { "annotation": "Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9U2M4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2M4#function" }, { "database": "UniProtKB", "id": "RU363085", "url": "https://www.uniprot.org/uniprotkb/RU363085#function" }, { "database": "UniProtKB", "id": "E1BLK4", "url": "https://www.uniprot.org/uniprotkb/E1BLK4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLK4", "url": "https://www.uniprot.org/uniprotkb/E1BLK4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CACNG6", "url": "https://www.uniprot.org/uniprotkb/E1BLK4", "locus": { "chromosome": "18", "start_pos": 61673746, "end_pos": 61659431, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021657", "url": "https://www.ensembl.org/id/ENSBTAG00000021657" } ] } } ], "crossref": [ { "id": "E1BLK4", "url": "https://alphafold.ebi.ac.uk/entry/E1BLK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021657", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021657", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "521616", "url": "https://www.ncbi.nlm.nih.gov/gene/521616", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008368", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008368", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521616", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521616", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PWQRCLP", "url": "https://omabrowser.org/oma/group/PWQRCLP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BLK4", "url": "https://www.orthodb.org/?gene=E1BLK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15025:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15025:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5576892", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576892", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5576893", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576893", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192817", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192817", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9U2M4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U2M4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLK4", "url": "https://www.uniprot.org/uniprotkb/E1BLK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLK4-1", "url": "https://www.uniprot.org/uniprotkb/E1BLK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMWSNFFLQEENRRRGAAARRRARGQPKAQMTPEREGKIKLALLLTSVGATLAVLAVGTEFWVELNTYRDNGSAVCDAAHLGLWKMCTKRLWQADVPAGRDTCGPAELPGEANCTYFKFFTTGENAHIFQRTTKKEVNQAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGLSGLLVLVSLEVFRHSVRALMQRVSPEPPVAPALTYEYSWSLGCGVGAGLILMLGGGCFLLLALPPGPWSPLCPKWGQRAP", "length": 260, "header": "tr|E1BLK4-1|E1BLK4_BOVIN Isoform 1 of Voltage-dependent calcium channel gamma-6 subunit OS=Bos taurus OX=9913 GN=CACNG6 PE=3 SV=3 CANONICAL=E1BLK4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9U2M4-1", "url": "https://www.uniprot.org/uniprotkb/E1BLK4/entry#A0AAA9U2M4-1", "sequence": { "sequence": "MMWSNFFLQEENRRRGAAARRRARGQPKAQMTPEREGKIKLALLLTSVGATLAVLAVGTEFWVELNTYRDNGSAVCDAAHLGLWKMCTKRLWQADVPAGRDTCGPAELPGEANCTYFKFFTTGENAHIFQRTTKKGLLVLVSLEVFRHSVRALMQRVSPEPPVAPALTYEYSWSLGCGVGAGLILMLGGGCFLLLALPPGPWSPLCPKWGQRAP", "length": 214, "header": "tr|A0AAA9U2M4-1|E1BLK4_BOVIN Computationally mapped isoform of Voltage-dependent calcium channel gamma-6 subunit OS=Bos taurus OX=9913 GN=CACNG6 PE=3 SV=2 CANONICAL=E1BLK4-1" }, "locus": { "chromosome": "18", "start_pos": 61673431, "end_pos": 61659473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101182.2", "url": "https://www.ensembl.org/id/ENSBTAT00000101182.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103835.2", "url": "https://www.ensembl.org/id/ENSBTAP00000103835.2" } ] } }, { "isoform_ac": "E1BLK4-1", "url": "https://www.uniprot.org/uniprotkb/E1BLK4/entry#E1BLK4-1", "sequence": { "sequence": "MMWSNFFLQEENRRRGAAARRRARGQPKAQMTPEREGKIKLALLLTSVGATLAVLAVGTEFWVELNTYRDNGSAVCDAAHLGLWKMCTKRLWQADVPAGRDTCGPAELPGEANCTYFKFFTTGENAHIFQRTTKKEVNQAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGLSGLLVLVSLEVFRHSVRALMQRVSPEPPVAPALTYEYSWSLGCGVGAGLILMLGGGCFLLLALPPGPWSPLCPKWGQRAP", "length": 260, "header": "tr|E1BLK4-1|E1BLK4_BOVIN Isoform 1 of Voltage-dependent calcium channel gamma-6 subunit OS=Bos taurus OX=9913 GN=CACNG6 PE=3 SV=3 CANONICAL=E1BLK4-1" }, "locus": { "chromosome": "18", "start_pos": 61673431, "end_pos": 61659473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028860.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028860.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028860.7", "url": "https://www.ensembl.org/id/ENSBTAP00000028860.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:521616", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521616", "resource": "KEGG Pathway" }, { "id": "R-BTA-5576892", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576892", "resource": "Reactome", "description": "Phase 0 - rapid depolarisation" }, { "id": "R-BTA-5576893", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576893", "resource": "Reactome", "description": "Phase 2 - plateau phase" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RNI9-1", "protein_name": "Voltage-dependent calcium channel gamma-6 subunit", "gene_name": "CACNG6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMMWSNFFLQEEDRRRGAASRRRAHKSGRMTPEQEGKIKLALLLTSVGATLAVLAVGTEFWVELNTYRDNGSAVCDAAHLGLWKMCTKRLWQADMPAGRDTCGPAELPGEANCTYFKFFTTGENARIFQRTTKKEVNVAAAVIAVLGLVVMALGCLCIIMVLSKGAEFLLRVGAVCFGLSGLLLLVSLEVFRHSVHALLQRVSPEPPPAPALTYEYSWSLGCGVGAGLVLILGGGCFLLLTLPPWPWGSLCPKSGPRAT", "length": 259 }, "evidence": [ { "id": "E1BLK4", "url": "https://omabrowser.org/oma/group/E1BLK4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8VHW3-1", "protein_name": "Voltage-dependent calcium channel gamma-6 subunit", "gene_name": "Cacng6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMWSNFFMQEEDRRRTAVGRRRAQEQQNLGLTPEREGKIKLGLLVAIVGATLAVLAVGTEFWVELNTYKTNGSAVCEAAHLGLWKVCIKRLWQADVPAGRETCGPAELPGEANCTYFKFFTTGENARIFQRTTKKEVNLAAAVIAVLGLTAMALGCLCVIMVLSKGAESLLRLGAVCFGLSGLLLFVSLEVFRHSVGALLQGVNPETPPAPRLAYEYSWSLGCGVGAGLILLLGGVCFLLLTLPSWPWRSLCPKWGGPTA", "length": 260 }, "evidence": [ { "id": "E1BLK4", "url": "https://omabrowser.org/oma/group/E1BLK4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VHW7-1", "protein_name": "Voltage-dependent calcium channel gamma-6 subunit", "gene_name": "Cacng6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMWSNFFMQEEDRRRTAVGRRRAQEQQNLGLTPEREGKIKLGLLVAIVGATLAVLAVGTEFWVELNTYKTNGSAVCEAAHLGLWKVCIKRLWQADVPAGRETCGPAELPGEANCTYFKFFTTGENAHIFQRTTKKEVNLAAAVIAVLGLTAMALGCLCVIMVLSKGAEFLLRLGAVCFGLSGLLLFVSLEVFRHSVRALLQGVNPETPPAPRLAYEYSWSLGCGVGAGLILLLGGVCFLLLTLPSWPWRSLCPKRGGPTA", "length": 260 }, "evidence": [ { "id": "E1BLK4", "url": "https://omabrowser.org/oma/group/E1BLK4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BXT2-1", "protein_name": "Voltage-dependent calcium channel gamma-6 subunit", "gene_name": "CACNG6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMWSNFFLQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTEFWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFFTTGENARIFQRTTKKEVNLAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGLSGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLLLTLPSWPWGSLCPKRGHRAT", "length": 260 }, "evidence": [ { "id": "E1BLK4", "url": "https://omabrowser.org/oma/group/E1BLK4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "E1BLK4", "url": "https://www.uniprot.org/uniprotkb/E1BLK4" } ], "pmid": "" }, { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "E1BLK4", "url": "https://www.uniprot.org/uniprotkb/E1BLK4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BLK4", "url": "https://www.uniprot.org/uniprotkb/E1BLK4" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "E1BLK4", "url": "https://www.uniprot.org/uniprotkb/E1BLK4" } ], "pmid": "" }, { "name": "L-type voltage-gated calcium channel complex", "id": "GO:1990454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990454", "evidence": [ { "database": "UniProtKB", "id": "E1BLK4", "url": "https://www.uniprot.org/uniprotkb/E1BLK4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "id": "GO:1902514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902514", "evidence": [ { "database": "UniProtKB", "id": "E1BLK4", "url": "https://www.uniprot.org/uniprotkb/E1BLK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLK4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 260, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLK4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLK4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLV6-1", "uniprot_ac": "E1BLV6", "uniprot_id": "E1BLV6_BOVIN", "mass": { "chemical_mass": 140388.0, "monoisotopic_mass": 140388.0 }, "refseq": { "ac": "XP_024839850", "name": "valine--tRNA ligase isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839850" }, "gene_names": [ { "name": "VARS1", "type": "recommended", "evidence": [ { "id": "E1BLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLV6" } ] }, { "name": "VARS1", "type": "synonym", "evidence": [ { "id": "XP_024839850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839850" } ] } ], "protein_names": [ { "name": "Valine--tRNA ligase", "type": "recommended", "evidence": [ { "id": "E1BLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLV6/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.9", "type": "synonym", "evidence": [ { "id": "E1BLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLV6/entry#names_and_taxonomy" } ] }, { "name": "Valyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "E1BLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLV6/entry#names_and_taxonomy" } ] }, { "name": "valine--tRNA ligase isoform X3", "type": "synonym", "evidence": [ { "id": "XP_024839850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839850" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLV6", "url": "https://www.uniprot.org/uniprotkb/E1BLV6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "VARS1", "url": "https://www.uniprot.org/uniprotkb/E1BLV6", "locus": { "chromosome": "23", "start_pos": 27546171, "end_pos": 27534313, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005631", "url": "https://www.ensembl.org/id/ENSBTAG00000005631" } ] } } ], "crossref": [ { "id": "E1BLV6", "url": "https://alphafold.ebi.ac.uk/entry/E1BLV6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005631", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005631", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00817", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00817", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07962", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07962", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22249", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22249", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505556", "url": "https://www.ncbi.nlm.nih.gov/gene/505556", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11946", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11946", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11946:SF109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11946:SF109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00043", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00043", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08264", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08264", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024839850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839850", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10704", "url": "https://www.rhea-db.org/rhea/10704", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BLV6", "url": "https://www.uniprot.org/uniprotkb/E1BLV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLV6-1", "url": "https://www.uniprot.org/uniprotkb/E1BLV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1265, "header": "tr|E1BLV6-1|E1BLV6_BOVIN Isoform 1 of Valine--tRNA ligase OS=Bos taurus OX=9913 GN=VARS1 PE=1 SV=5 CANONICAL=E1BLV6-1" }, "isoforms": [ { "isoform_ac": "E1BLV6-1", "url": "https://www.uniprot.org/uniprotkb/E1BLV6/entry#E1BLV6-1", "sequence": { "sequence": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MX83-1", "url": "https://www.uniprot.org/uniprotkb/F1MX83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "DRRSALRATPGAEPLARRETGRGASAGAGSPSPAGPAEPGAKVSSPTETERCIESLIAVFQKHAGRDGNNSKLSKAEFLIFMNTELGAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLIGGLAIACHESFIKSASSQK", "length": 142, "header": "tr|A0ABI0NLF3-1|A0ABI0NLF3_BOVIN Isoform 1 of Protein S100 OS=Bos taurus OX=9913 GN=S100A11 PE=1 SV=1 CANONICAL=A0ABI0NLF3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NLF3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLF3/entry#A0ABI0NLF3-1", "sequence": { "sequence": "DRRSALRATPGAEPLARRETGRGASAGAGSPSPAGPAEPGAKVSSPTETERCIESLIAVFQKHAGRDGNNSKLSKAEFLIFMNTELGAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLIGGLAIACHESFIKSASSQK", "length": 142, "header": "tr|A0ABI0NLF3-1|A0ABI0NLF3_BOVIN Isoform 1 of Protein S100 OS=Bos taurus OX=9913 GN=S100A11 PE=1 SV=1 CANONICAL=A0ABI0NLF3-1" }, "locus": { "chromosome": "3", "start_pos": 18733416, "end_pos": 18729120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148326.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148326.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105897.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105897.1" } ] } }, { "isoform_ac": "F1MX83-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLF3/entry#F1MX83-1", "sequence": { "sequence": "TITDPGSESRASDSSYNSVANCTEAKVSSPTETERCIESLIAVFQKHAGRDGNNSKLSKAEFLIFMNTELGAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLIGGLAIACHESFIKSASSQK", "length": 126, "header": "tr|F1MX83-1|A0ABI0NLF3_BOVIN Computationally mapped isoform of Protein S100 OS=Bos taurus OX=9913 GN=S100A11 PE=1 SV=3 CANONICAL=A0ABI0NLF3-1" }, "locus": { "chromosome": "3", "start_pos": 18733416, "end_pos": 18727817, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020148.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020148.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020148.5", "url": "https://www.ensembl.org/id/ENSBTAP00000020148.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "G3HUU6-1", "protein_name": "Protein S100", "gene_name": "S100a11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSKPTETERCIESLIAVFQKYSGKDGNSCQLSKTEFLTFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLIGGLALACHESFLKASQKRV", "length": 100 }, "evidence": [ { "id": "A0ABI0NLF3", "url": "https://omabrowser.org/oma/group/A0ABI0NLF3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P24479-1", "protein_name": "Protein S100-A11", "gene_name": "S100A11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSKVSPTETERCIESLLAVFQRYAGREGDNLKLSKKEFRTFMNTELASFTKNQKDPAVVDRMMKRLDINSDGQLDFQEFLNLIGGIAVACHDALLVQPPHP", "length": 101 }, "evidence": [ { "id": "A0ABI0NLF3", "url": "https://omabrowser.org/oma/group/A0ABI0NLF3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P31949-1", "protein_name": "Protein S100-A11", "gene_name": "S100A11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT", "length": 105 }, "evidence": [ { "id": "A0ABI0NLF3", "url": "https://omabrowser.org/oma/group/A0ABI0NLF3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P31950-1", "protein_name": "Protein S100-A11", "gene_name": "S100A11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKRPTETERCIESLIAIFQKHAGRDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEFLNLIGGLAIACHDSFIKSTQK", "length": 99 }, "evidence": [ { "id": "A0ABI0NLF3", "url": "https://omabrowser.org/oma/group/A0ABI0NLF3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P50543-1", "protein_name": "Protein S100-A11", "gene_name": "S100a11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTETERCIESLIAVFQKYSGKDGNNTQLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNCDGQLDFQEFLNLIGGLAIACHDSFIQTSQKRI", "length": 98 }, "evidence": [ { "id": "A0ABI0NLF3", "url": "https://omabrowser.org/oma/group/A0ABI0NLF3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6B345-1", "protein_name": "Protein S100-A11", "gene_name": "S100a11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETERCIESLIAVFQKYSGKDGNSCHLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLIGGLAIACHESFLQTSQKRI", "length": 98 }, "evidence": [ { "id": "A0ABI0NLF3", "url": "https://omabrowser.org/oma/group/A0ABI0NLF3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLF3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLF3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLF3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLF3" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NLF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLF3" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 129, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NM64-1", "uniprot_ac": "A0ABI0NM64", "uniprot_id": "A0ABI0NM64_BOVIN", "mass": { "chemical_mass": 33645.0, "monoisotopic_mass": 33645.0 }, "refseq": { "ac": "NP_001178261", "name": "armadillo repeat-containing protein 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178261" }, "gene_names": [ { "name": "ARMC10", "type": "recommended", "evidence": [ { "id": "A0ABI0NM64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM64" } ] }, { "name": "ARMC10", "type": "synonym", "evidence": [ { "id": "NP_001178261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178261" } ] } ], "protein_names": [ { "name": "Armadillo repeat containing 10", "type": "synonym", "evidence": [ { "id": "A0ABI0NM64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM64/entry#names_and_taxonomy" } ] }, { "name": "armadillo repeat-containing protein 10", "type": "synonym", "evidence": [ { "id": "NP_001178261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178261" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM64" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARMC10", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM64", "locus": { "chromosome": "4", "start_pos": 44501446, "end_pos": 44363535, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014161", "url": "https://www.ensembl.org/id/ENSBTAG00000014161" } ] } } ], "crossref": [ { "id": "ENSBTAG00000014161", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014161", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100138038", "url": "https://www.ncbi.nlm.nih.gov/gene/100138038", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100138038", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138038", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MK64", "url": "https://www.orthodb.org/?gene=A0A3Q1MK64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1B717", "url": "https://www.orthodb.org/?gene=E1B717", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15712:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15712:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178261", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178261", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MK64", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MK64-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM64-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B717", "url": "https://www.uniprot.org/uniprotkb/E1B717", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B717-1", "url": "https://www.uniprot.org/uniprotkb/E1B717-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGARDVGWVAAGLVLAAGACYCFYKLTRGRRRGGRQLRLRPSRSAEDLTSGSYDDTLNAEQVQKLLYLLESTEDPVIIERALVTLGNNAAFSANQIVIRELGGIPIVGSKINNPNQSIKEKALNALNNLSVNVENQIKIKVYVSQVCEDVIAGPLNSAVQLAGLRLLTNMTVTNDHQDMLSSYITDLFHVLVTGNGSTKVQVLKLLLNLSENPAMTDRLLDAQVDSSFLSLLDGHVPKEILLRALTLLQNITNCLNEEHRLAAQPTFPEGSLFSLLYGKECAQKMKALVHHHDADVKEKVTMIPKF", "length": 307, "header": "tr|A0ABI0NM64-1|A0ABI0NM64_BOVIN Isoform 1 of Armadillo repeat containing 10 OS=Bos taurus OX=9913 GN=ARMC10 PE=4 SV=1 CANONICAL=A0ABI0NM64-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MK64-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM64/entry#A0A3Q1MK64-1", "sequence": { "sequence": "MGGARDVGWVAAGLVLAAGACYCFYKLTRGRRRGGRQLRLRPSRSAEDLTSGSYDDTLNAEQVQKLLYLLESTEDPVIIERALVTLGNNAAFSANQIVIRELGGIPIVGSKINNPNQSIKEKALNALNNLSVNVENQIKIKVYVSQVCEDVIAGPLNSAVQLAGLRLLTNMTVTNDHQDMLSSYITDLFHVLVTGNGSTKVDSSFLSLLDGHVPKEILLRALTLLQNITNCLNEEHRLAAQPTFPEGSLFSLLYGKECAQKMKALVHHHDADVKEKVTMIPKFW", "length": 284, "header": "tr|A0A3Q1MK64-1|A0ABI0NM64_BOVIN Computationally mapped isoform of Armadillo repeat containing 10 OS=Bos taurus OX=9913 GN=ARMC10 PE=4 SV=3 CANONICAL=A0ABI0NM64-1" }, "locus": { "chromosome": "4", "start_pos": 44423844, "end_pos": 44363902, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084299.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084299.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069589.3", "url": "https://www.ensembl.org/id/ENSBTAP00000069589.3" } ] } }, { "isoform_ac": "A0AAA9SQM1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM64/entry#A0AAA9SQM1-1", "sequence": { "sequence": "MGGARDVGWVAAGLVLAAGACYCFYKLTRGRRRGGRQLRLRPSRSAEDLTSGSYDDTLNAEQVQKLLYLLESTEDPVIIERALVTLGNNAAFSANQIVIRELGGIPIVGSKINNPNQSIKEKALNALNNLSVNVENQIKIKVDSSFLSLLDGHVPKEILLRALTLLQNITNCLNEEHRLAAQPTFPEGSLFSLLYGKECAQKMKALVHHHDADVKEKVTMIPKFW", "length": 225, "header": "tr|A0AAA9SQM1-1|A0ABI0NM64_BOVIN Computationally mapped isoform of Armadillo repeat containing 10 OS=Bos taurus OX=9913 GN=ARMC10 PE=4 SV=2 CANONICAL=A0ABI0NM64-1" }, "locus": { "chromosome": "4", "start_pos": 44423844, "end_pos": 44363902, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093917.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093917.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087656.2", "url": "https://www.ensembl.org/id/ENSBTAP00000087656.2" } ] } }, { "isoform_ac": "A0ABI0NM64-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM64/entry#A0ABI0NM64-1", "sequence": { "sequence": "MGGARDVGWVAAGLVLAAGACYCFYKLTRGRRRGGRQLRLRPSRSAEDLTSGSYDDTLNAEQVQKLLYLLESTEDPVIIERALVTLGNNAAFSANQIVIRELGGIPIVGSKINNPNQSIKEKALNALNNLSVNVENQIKIKVYVSQVCEDVIAGPLNSAVQLAGLRLLTNMTVTNDHQDMLSSYITDLFHVLVTGNGSTKVQVLKLLLNLSENPAMTDRLLDAQVDSSFLSLLDGHVPKEILLRALTLLQNITNCLNEEHRLAAQPTFPEGSLFSLLYGKECAQKMKALVHHHDADVKEKVTMIPKF", "length": 307, "header": "tr|A0ABI0NM64-1|A0ABI0NM64_BOVIN Isoform 1 of Armadillo repeat containing 10 OS=Bos taurus OX=9913 GN=ARMC10 PE=4 SV=1 CANONICAL=A0ABI0NM64-1" }, "locus": { "chromosome": "4", "start_pos": 44423844, "end_pos": 44363902, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139530.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139530.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106460.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106460.1" } ] } }, { "isoform_ac": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NJR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC528802", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S0N0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0N0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0N0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRP6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRP6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJR1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NK94", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NK94-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P495", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P495", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P495-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P495-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLCTFPRRNGGSLMRPRDAYTAMSCWRPLHWLRPWLCTQHTCVPSSQGPGENRSRRSELWTPGSLCSAPHPCVLPGCWQRAEMKEKTSEQNASVEVPQIITSKTDLSIQKAYPWEMGNLDVEGGLHLTEDLRVNPVQTLCRAGVKFQQHSGEKLFRRDMGKAFMKTRIVHTTKKSFPCQEPGKDFPVSSDLLQYQVTPQGDTECVEASHNGLRPYKCSACGKTFCRKYRLAEHQRVHTGERPYECSECGKTFSYKHILVQHRRVHTGERPFKCRECGKAFSNRPTLARHRRIHTGEKPYECSECGKLFSQSSSLNEHQRIHTGSRPYKCNECGKFFTSNSNLVKHRRVHTGTKPYECSECGKFFNQSPSLIKHQRIHTGERPYECSECGKLFSQSCTLIKHQRVHTGARPYKCTECGKLFSQSFGLTQHQRIHTGERPYECTECGELFSQSTQLTQHRKIHTRAGPLECGRCGEVFSQRSTLIEHQKHHSPDRPYECSECKKAFSRRSSLLRHQKVHAGQRPSNEMSRESNNELSP", "length": 537, "header": "tr|A0ABI0NJR1-1|A0ABI0NJR1_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC528802 PE=3 SV=1 CANONICAL=A0ABI0NJR1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S0N0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1/entry#A0AAA9S0N0-1", "sequence": { "sequence": "MDLFFLCQTCIVMGLPTSTKIYMKFTPISLLSGCWQRAEMKEKTSEQNASVEVPQIITSKTDLSIQKAYPWEMGNLDVEGGLHLTEDLRVNPVQTLCRAGVKFQQHSGEKLFRRDMGKAFMKTRIVHTTKKSFPCQEPGKDFPVSSDLLQYQVTPQGDTECVEASHNGLRPYKCSACGKTFCRKYRLAEHQRVHTGERPYECSECGKTFSYKHILVQHRRVHTGERPFKCRECGKAFSNRPTLARHRRIHTGEKPYECSECGKLFSQSSSLNEHQRIHTGSRPYKCNECGKFFTSNSNLVKHRRVHTGTKPYECSECGKFFNQSPSLIKHQRIHTGERPYECSECGKLFSQSCTLIKHQRVHTGARPYKCTECGKLFSQSFGLTQHQRIHTGERPYECTECGELFSQSTQLTQHRKIHTRAGPLECGRCGEVFSQRSTLIEHQKHHSPDRPYECSECKKAFSRRSSLLRHQKVHAGQRPSNEMSRESNNELSP", "length": 493, "header": "tr|A0AAA9S0N0-1|A0ABI0NJR1_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC528802 PE=3 SV=2 CANONICAL=A0ABI0NJR1-1" }, "locus": { "chromosome": "18", "start_pos": 64640986, "end_pos": 64639508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093649.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093649.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077193.2", "url": "https://www.ensembl.org/id/ENSBTAP00000077193.2" } ] } }, { "isoform_ac": "A0AAA9TRP6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1/entry#A0AAA9TRP6-1", "sequence": { "sequence": "MVPIQLCTQHTCVPSSQGPGENRSRRSELWTPGSLCSAPHPCVLPGCWQRAEMKEKTSEQNASVEVPQIITSKTDLSIQKAYPWEMGNLDVEGGLHLTEDLRVNPVQTLCRAGVKFQQHSGEKLFRRDMGKAFMKTRIVHTTKKSFPCQEPGKDFPVSSDLLQYQVTPQGDTECVEASHNGLRPYKCSACGKTFCRKYRLAEHQRVHTGERPYECSECGKTFSYKHILVQHRRVHTGERPFKCRECGKAFSNRPTLARHRRIHTGEKPYECSECGKLFSQSSSLNEHQRIHTGSRPYKCNECGKFFTSNSNLVKHRRVHTGTKPYECSECGKFFNQSPSLIKHQRIHTGERPYECSECGKLFSQSCTLIKHQRVHTGARPYKCTECGKLFSQSFGLTQHQRIHTGERPYECTECGELFSQSTQLTQHRKIHTRAGPLECGRCGEVFSQRSTLIEHQKHHSPDRPYECSECKKAFSRRSSLLRHQKVHAGQRPSNEMSRESNNELSP", "length": 506, "header": "tr|A0AAA9TRP6-1|A0AAA9TRP6_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC528802 PE=3 SV=1 CANONICAL=A0ABI0NJR1-1" }, "locus": { "chromosome": "18", "start_pos": 64640986, "end_pos": 64632584, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128868.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128868.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099144.2", "url": "https://www.ensembl.org/id/ENSBTAP00000099144.2" } ] } }, { "isoform_ac": "A0ABI0NJR1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1/entry#A0ABI0NJR1-1", "sequence": { "sequence": "MWLCTFPRRNGGSLMRPRDAYTAMSCWRPLHWLRPWLCTQHTCVPSSQGPGENRSRRSELWTPGSLCSAPHPCVLPGCWQRAEMKEKTSEQNASVEVPQIITSKTDLSIQKAYPWEMGNLDVEGGLHLTEDLRVNPVQTLCRAGVKFQQHSGEKLFRRDMGKAFMKTRIVHTTKKSFPCQEPGKDFPVSSDLLQYQVTPQGDTECVEASHNGLRPYKCSACGKTFCRKYRLAEHQRVHTGERPYECSECGKTFSYKHILVQHRRVHTGERPFKCRECGKAFSNRPTLARHRRIHTGEKPYECSECGKLFSQSSSLNEHQRIHTGSRPYKCNECGKFFTSNSNLVKHRRVHTGTKPYECSECGKFFNQSPSLIKHQRIHTGERPYECSECGKLFSQSCTLIKHQRVHTGARPYKCTECGKLFSQSFGLTQHQRIHTGERPYECTECGELFSQSTQLTQHRKIHTRAGPLECGRCGEVFSQRSTLIEHQKHHSPDRPYECSECKKAFSRRSSLLRHQKVHAGQRPSNEMSRESNNELSP", "length": 537, "header": "tr|A0ABI0NJR1-1|A0ABI0NJR1_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC528802 PE=3 SV=1 CANONICAL=A0ABI0NJR1-1" }, "locus": { "chromosome": "18", "start_pos": 64640986, "end_pos": 64638179, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146484.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146484.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104728.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104728.1" } ] } }, { "isoform_ac": "A0ABI0NK94-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1/entry#A0ABI0NK94-1", "sequence": { "sequence": "MAGFRPYQERVLCATLFRCQGCWQRAEMKEKTSEQNASVEVPQIITSKTDLSIQKAYPWEMGNLDVEGGLHLTEDLRVNPVQTLCRAGVKFQQHSGEKLFRRDMGKAFMKTRIVHTTKKSFPCQEPGKDFPVSSDLLQYQVTPQGDTECVEASHNGLRPYKCSACGKTFCRKYRLAEHQRVHTGERPYECSECGKTFSYKHILVQHRRVHTGERPFKCRECGKAFSNRPTLARHRRIHTGEKPYECSECGKLFSQSSSLNEHQRIHTGSRPYKCNECGKFFTSNSNLVKHRRVHTGTKPYECSECGKFFNQSPSLIKHQRIHTGERPYECSECGKLFSQSCTLIKHQRVHTGARPYKCTECGKLFSQSFGLTQHQRIHTGERPYECTECGELFSQSTQLTQHRKIHTRAGPLECGRCGEVFSQRSTLIEHQKHHSPDRPYECSECKKAFSRRSSLLRHQKVHAGQRPSNEMSRESNNELSP", "length": 481, "header": "tr|A0ABI0NK94-1|A0ABI0NK94_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC528802 PE=3 SV=1 CANONICAL=A0ABI0NJR1-1" }, "locus": { "chromosome": "18", "start_pos": 64640986, "end_pos": 64638970, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146686.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146686.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105069.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105069.1" } ] } }, { "isoform_ac": "A0ABI0P495-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1/entry#A0ABI0P495-1", "sequence": { "sequence": "MVPIQVPHSEEARMDPSLGPVTFEDVAVYFSQEEWRILDETQRRLYSYVMLETFALVASLGCWQRAEMKEKTSEQNASVEVPQIITSKTDLSIQKAYPWEMGNLDVEGGLHLTEDLRVNPVQTLCRAGVKFQQHSGEKLFRRDMGKAFMKTRIVHTTKKSFPCQEPGKDFPVSSDLLQYQVTPQGDTECVEASHNGLRPYKCSACGKTFCRKYRLAEHQRVHTGERPYECSECGKTFSYKHILVQHRRVHTGERPFKCRECGKAFSNRPTLARHRRIHTGEKPYECSECGKLFSQSSSLNEHQRIHTGSRPYKCNECGKFFTSNSNLVKHRRVHTGTKPYECSECGKFFNQSPSLIKHQRIHTGERPYECSECGKLFSQSCTLIKHQRVHTGARPYKCTECGKLFSQSFGLTQHQRIHTGERPYECTECGELFSQSTQLTQHRKIHTRAGPLECGRCGEVFSQRSTLIEHQKHHSPDRPYECSECKKAFSRRSSLLRHQKVHAGQRPSNEMSRESNNELSP", "length": 521, "header": "tr|A0ABI0P495-1|A0ABI0P495_BOVIN Computationally mapped isoform of Zinc finger protein OZF-like OS=Bos taurus OX=9913 GN=LOC528802 PE=3 SV=1 CANONICAL=A0ABI0NJR1-1" }, "locus": { "chromosome": "18", "start_pos": 64640986, "end_pos": 64632584, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153145.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153145.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106544.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106544.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:528802", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528802", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NJR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR1" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 216, "end_pos": 243, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 366, "end_pos": 368 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NM98-1", "uniprot_ac": "A0ABI0NM98", "uniprot_id": "A0ABI0NM98_BOVIN", "mass": { "chemical_mass": 339347.0, "monoisotopic_mass": 339347.0 }, "refseq": { "ac": "XP_059742063", "name": "kalirin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742063" }, "gene_names": [ { "name": "KALRN", "type": "recommended", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "name": "KALRN", "type": "synonym", "evidence": [ { "id": "XP_059742063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742063" } ] } ], "protein_names": [ { "name": "Kalirin", "type": "recommended", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98/entry#names_and_taxonomy" } ] }, { "name": "Protein Duo", "type": "synonym", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98/entry#names_and_taxonomy" } ] }, { "name": "Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain", "type": "synonym", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98/entry#names_and_taxonomy" } ] }, { "name": "kalirin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059742063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742063" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KALRN", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98", "locus": { "chromosome": "1", "start_pos": 68942910, "end_pos": 68434070, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002640", "url": "https://www.ensembl.org/id/ENSBTAG00000002640" } ] } } ], "crossref": [ { "id": "ENSBTAG00000002640", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002640", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000053238", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000053238", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11852", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11852", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11853", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11853", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13240", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13240", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13241", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13241", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14115", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14115", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540675", "url": "https://www.ncbi.nlm.nih.gov/gene/540675", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058918", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058918", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MB16", "url": "https://www.orthodb.org/?gene=A0A3Q1MB16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MXJ6", "url": "https://www.orthodb.org/?gene=F1MXJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22826", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22826", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22826:SF106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22826:SF106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22826:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22826:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00435", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00435", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13716", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13716", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16609", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16609", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23323", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23323", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23587", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23587", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059742063", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742063", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MB16", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MB16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MB16-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MB16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S507", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S507", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S507-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S507-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV86", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV86-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM98-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MXJ6", "url": "https://www.uniprot.org/uniprotkb/F1MXJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MXJ6-1", "url": "https://www.uniprot.org/uniprotkb/F1MXJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQHALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQSLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIMEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQQKAEALLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPSAASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEYYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKEGLEVMLSVPKRANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPIQLPKTPAKQRNNSKRDGVEDVDSQGDGSSQPDTISIASRTSQNTADSDKLSGGCELTVVLQDFNAGHSSELSIQVGQTVELLERPSERPGWCLVRTTERSPPQEGLVPSSALCISHSRSSVEMDCFFPLVKDAYSHSSSENGGKSESVANLQAQPSLNSIHSSPGPKRSTNTLKKWLTSPVRRLNSGKADGNIKKQKKVRDGRKSFDLGSPKPGDETTPQGDSADESKKGWGEDEADEESHTPLPPPMKIFDNDPTQDEMSSSLLAARQASTEVPTAADLVSAIEQLVKSKLSLEGGSYRGSLKDPTGCLNEGMTPPTPPRNLEEEQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKGVPEDMRGKDKIVFGNIHQIYDWHKDVFLGELEKCIQEQDRLAQLFIKYERKLHIYVWYCQNKPRSEYIVAEYDAYFEEVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEENVDNDPCKFALLNRETSERVILQAANADIQQAWVQDINQVLETQRDFLNALQSPIEYQRKERSTAVMRSQPARVPQASPRPYSSIPVGSEKPPKGSSYNPPLPPLKISTSNGSPGFDYHQAGDKFEASKNDLGGCNGASSMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILTPLTKAMAATENSDGSIKKSCSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVTLQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIAANDHGTASTSATVKVQGVPAAPNRPIAQERSCTSVILRWLPPSSTGNCTISGYTVEYREEGSQAWQQSVASTLDTYLVIEDLSPGSPYQFRVSASNPWGISLPSEPSEFVRLPDYDAAADGATISWKENFDSAYTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLIDLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQNDVRPIPNVKSYIVNRLNQGT", "length": 2987, "header": "tr|A0ABI0NM98-1|A0ABI0NM98_BOVIN Isoform 1 of Kalirin OS=Bos taurus OX=9913 GN=KALRN PE=3 SV=1 CANONICAL=A0ABI0NM98-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MB16-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98/entry#A0A3Q1MB16-1", "sequence": { "sequence": "MKGGDRAYTRGPSLGWLFAKCCCCFPCRDAYSHSSSENGGKSESVANLQAQPSLNSIHSSPGPKRSTNTLKKWLTSPVRRLNSGKADGNIKKQKKVRDGRKSFDLGSPKPGDETTPQGDSADEKSKKGWGEDEADEESHTPLPPPMKIFDNDPTQDEMSSSLLAARQASTEVPTAADLVSAIEQLVKSKLSLEGGSYRGSLKDPTGCLNEGMTPPTPPRNLEEEQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKGVPEDMRGKDKIVFGNIHQIYDWHKDVFLGELEKCIQEQDRLAQLFIKYERKLHIYVWYCQNKPRSEYIVAEYDAYFEEVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEENVDNDPCKFALLNRETSERVILQAANADIQQAWVQDINQVLETQRDFLNALQSPIEYQRKERSTAVMRSQPARVPQASPRPYSSIPVGSEKPPKGSSYNPPLPPLKISTSNGSPGFDYHQAGDKFEASKQNDLGGCNGASSMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILTPLTKAMAATENSDGSIKKSCSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVTLQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIAANDHGTASTSATVKVQGVPAAPNRPIAQERSCTSVILRWLPPSSTGNCTISGYTVEYREEGSQAWQQSVASTLDTYLVIEDLSPGSPYQFRVSASNPWGISLPSEPSEFVRLPDYDAAADGATISWKENFDSAYTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLIDLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQNDVRPIPNVKSYIVNRLNQGT", "length": 1290, "header": "tr|A0A3Q1MB16-1|A0ABI0NM98_BOVIN Computationally mapped isoform of Kalirin OS=Bos taurus OX=9913 GN=KALRN PE=3 SV=2 CANONICAL=A0ABI0NM98-1" }, "locus": { "chromosome": "1", "start_pos": 69120009, "end_pos": 69003410, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071142.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071142.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065842.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065842.2" } ] } }, { "isoform_ac": "A0AAA9S507-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98/entry#A0AAA9S507-1", "sequence": { "sequence": "MTDRFWEQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQHALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQSLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIMEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQQKAEALLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPSAASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEYYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKEGLEVMLSVPKRANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPIQLPKTPAKQRNNSKRDGVEDVDSQGDGSSQPDTISIASRTSQNTADSDKDCSTGN", "length": 1649, "header": "tr|A0AAA9S507-1|A0ABI0NM98_BOVIN Computationally mapped isoform of Kalirin OS=Bos taurus OX=9913 GN=KALRN PE=3 SV=1 CANONICAL=A0ABI0NM98-1" }, "locus": { "chromosome": "1", "start_pos": 68941518, "end_pos": 68500078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123523.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123523.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078314.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078314.1" } ] } }, { "isoform_ac": "A0AAA9TDJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98/entry#A0AAA9TDJ2-1", "sequence": { "sequence": "MTDRFWEQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQHALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQSLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIMEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQQKAEALLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPSAASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEYYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKEGLEVMLSVPKRANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPIQLPKTPAKQRNNSKRDGVEDVDSQGDGSSQPDTISIASRTSQNTADSDKDGNLAPRWYLGPGDPFSTYV", "length": 1663, "header": "tr|A0AAA9TDJ2-1|A0ABI0NM98_BOVIN Computationally mapped isoform of Kalirin OS=Bos taurus OX=9913 GN=KALRN PE=3 SV=2 CANONICAL=A0ABI0NM98-1" }, "locus": { "chromosome": "1", "start_pos": 68941906, "end_pos": 68500078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108587.2", "url": "https://www.ensembl.org/id/ENSBTAT00000108587.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094942.2", "url": "https://www.ensembl.org/id/ENSBTAP00000094942.2" } ] } }, { "isoform_ac": "A0AAA9TV86-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98/entry#A0AAA9TV86-1", "sequence": { "sequence": "MNPPEGAAEEGGAADSDVDAFFRTAKCNFLPARSLTAGYSKG", "length": 42, "header": "tr|A0AAA9TV86-1|A0ABI0NM98_BOVIN Computationally mapped isoform of Kalirin OS=Bos taurus OX=9913 GN=KALRN PE=3 SV=1 CANONICAL=A0ABI0NM98-1" }, "locus": { "chromosome": "1", "start_pos": 68567129, "end_pos": 68434269, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114073.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114073.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102275.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102275.1" } ] } }, { "isoform_ac": "A0ABI0NM98-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98/entry#A0ABI0NM98-1", "sequence": { "sequence": "MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQHALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQSLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIMEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQQKAEALLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPSAASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEYYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKEGLEVMLSVPKRANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPIQLPKTPAKQRNNSKRDGVEDVDSQGDGSSQPDTISIASRTSQNTADSDKLSGGCELTVVLQDFNAGHSSELSIQVGQTVELLERPSERPGWCLVRTTERSPPQEGLVPSSALCISHSRSSVEMDCFFPLVKDAYSHSSSENGGKSESVANLQAQPSLNSIHSSPGPKRSTNTLKKWLTSPVRRLNSGKADGNIKKQKKVRDGRKSFDLGSPKPGDETTPQGDSADESKKGWGEDEADEESHTPLPPPMKIFDNDPTQDEMSSSLLAARQASTEVPTAADLVSAIEQLVKSKLSLEGGSYRGSLKDPTGCLNEGMTPPTPPRNLEEEQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKGVPEDMRGKDKIVFGNIHQIYDWHKDVFLGELEKCIQEQDRLAQLFIKYERKLHIYVWYCQNKPRSEYIVAEYDAYFEEVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEENVDNDPCKFALLNRETSERVILQAANADIQQAWVQDINQVLETQRDFLNALQSPIEYQRKERSTAVMRSQPARVPQASPRPYSSIPVGSEKPPKGSSYNPPLPPLKISTSNGSPGFDYHQAGDKFEASKNDLGGCNGASSMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILTPLTKAMAATENSDGSIKKSCSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVTLQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIAANDHGTASTSATVKVQGVPAAPNRPIAQERSCTSVILRWLPPSSTGNCTISGYTVEYREEGSQAWQQSVASTLDTYLVIEDLSPGSPYQFRVSASNPWGISLPSEPSEFVRLPDYDAAADGATISWKENFDSAYTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLIDLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQNDVRPIPNVKSYIVNRLNQGT", "length": 2987, "header": "tr|A0ABI0NM98-1|A0ABI0NM98_BOVIN Isoform 1 of Kalirin OS=Bos taurus OX=9913 GN=KALRN PE=3 SV=1 CANONICAL=A0ABI0NM98-1" }, "locus": { "chromosome": "1", "start_pos": 69120009, "end_pos": 68434269, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141202.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141202.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106540.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106540.1" } ] } }, { "isoform_ac": "F1MXJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98/entry#F1MXJ6-1", "sequence": { "sequence": "MTDRFWEQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQHALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQSLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIMEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQQKAEALLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQACTLARRNAEVFLKYIHRNNVSMPSAASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEYYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKEGLEVMLSVPKRANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPIQLPKTPAKQRNNSKRDGVEDVDSQGDGSSQPDTISIASRTSQNTADSDKDGNLAPRWYLGPGDPFSTYV", "length": 1613, "header": "tr|F1MXJ6-1|A0ABI0NM98_BOVIN Computationally mapped isoform of Kalirin OS=Bos taurus OX=9913 GN=KALRN PE=3 SV=4 CANONICAL=A0ABI0NM98-1" }, "locus": { "chromosome": "1", "start_pos": 68941906, "end_pos": 68500078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032306.7", "url": "https://www.ensembl.org/id/ENSBTAT00000032306.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032241.6", "url": "https://www.ensembl.org/id/ENSBTAP00000032241.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1914, "start_aa": "Thr", "end_pos": 1914, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1914", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1005, "end_pos": 1007, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1086, "end_pos": 1088, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1558, "end_pos": 1560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1607, "end_pos": 1609, "annotation": "n_glycosylation_sequon" }, { 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"A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NJH4-1", "uniprot_ac": "A0ABI0NJH4", "uniprot_id": "A0ABI0NJH4_BOVIN", "mass": { "chemical_mass": 61975.0, "monoisotopic_mass": 61975.0 }, "refseq": {}, "gene_names": [ { "name": "GNS", "type": "recommended", "evidence": [ { "id": "A0ABI0NJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ] } ], "protein_names": [ { "name": "N-acetylglucosamine-6-sulfatase", "type": "recommended", "evidence": [ { "id": "A0ABI0NJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4/entry#names_and_taxonomy" } ] }, { "name": "3.1.6.14", "type": "synonym", "evidence": [ { "id": "A0ABI0NJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4/entry#names_and_taxonomy" } ] }, { "name": "Glucosamine-6-sulfatase", "type": "synonym", "evidence": [ { "id": "A0ABI0NJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Hydrolyzes 6-sulfate groups in N-acetyl-d-glucosaminide units of heparin sulfate and keratan sulfate.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4#function" }, { "database": "UniProtKB", "id": "ARBA00057082", "url": "https://www.uniprot.org/uniprotkb/ARBA00057082#function" }, { "database": "UniProtKB", "id": "A0ABI0P2D0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2D0#function" }, { "database": "UniProtKB", "id": "A0ABI0NQK8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK8#function" }, { "database": "UniProtKB", "id": "F1MXZ0", "url": "https://www.uniprot.org/uniprotkb/F1MXZ0#function" }, { "database": "UniProtKB", "id": "A0AAA9S5Y3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Y3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GNS", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4", "locus": { "chromosome": "5", "start_pos": 49103597, "end_pos": 49053899, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017465", "url": "https://www.ensembl.org/id/ENSBTAG00000017465" } ] } } ], "crossref": [ { "id": "ENSBTAG00000017465", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017465", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16147", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16147", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WCHGEHE", "url": "https://omabrowser.org/oma/group/WCHGEHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MXZ0", "url": "https://www.orthodb.org/?gene=F1MXZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43108:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43108:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022857", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022857", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-432720", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432720", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S5Y3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJH4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQK8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQK8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2D0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2D0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MXZ0", "url": "https://www.uniprot.org/uniprotkb/F1MXZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MXZ0-1", "url": "https://www.uniprot.org/uniprotkb/F1MXZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLLSLAPDRPRRGGPRHLTSGSPALLLLLLGGCLGVSGAAKSSRRPNVVLLLADDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLGHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQNAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFNGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYSLNKTQMDGMSFLPILKGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSERWNLQYCEFDDQEVFVEVYNLTADPHQLNNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNHGSVRTRRFSKHLL", "length": 552, "header": "tr|A0ABI0NJH4-1|A0ABI0NJH4_BOVIN Isoform 1 of N-acetylglucosamine-6-sulfatase OS=Bos taurus OX=9913 GN=GNS PE=3 SV=1 CANONICAL=A0ABI0NJH4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S5Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4/entry#A0AAA9S5Y3-1", "sequence": { "sequence": "MRLLSLAPDRPRRGGPRHLTSGSPALPPPPPLLLLLLLLGGCLGVSGAAKSSRRPNVVLLLADDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLGHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQNAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFNGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYSLNKTQMDGMSFLPILKGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSERWNLQYCEFDDQEVFVEVYNLTADPHQLNNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGLPGSSVHGISQARRLEWVATSFSRRSS", "length": 562, "header": "tr|A0AAA9S5Y3-1|A0ABI0NJH4_BOVIN Computationally mapped isoform of N-acetylglucosamine-6-sulfatase OS=Bos taurus OX=9913 GN=GNS PE=3 SV=1 CANONICAL=A0ABI0NJH4-1" }, "locus": { "chromosome": "5", "start_pos": 49100361, "end_pos": 49053978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094349.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094349.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079249.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079249.1" } ] } }, { "isoform_ac": "A0ABI0NJH4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4/entry#A0ABI0NJH4-1", "sequence": { "sequence": "MRLLSLAPDRPRRGGPRHLTSGSPALLLLLLGGCLGVSGAAKSSRRPNVVLLLADDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLGHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQNAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFNGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYSLNKTQMDGMSFLPILKGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSERWNLQYCEFDDQEVFVEVYNLTADPHQLNNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNHGSVRTRRFSKHLL", "length": 552, "header": "tr|A0ABI0NJH4-1|A0ABI0NJH4_BOVIN Isoform 1 of N-acetylglucosamine-6-sulfatase OS=Bos taurus OX=9913 GN=GNS PE=3 SV=1 CANONICAL=A0ABI0NJH4-1" }, "locus": { "chromosome": "5", "start_pos": 49101027, "end_pos": 49053978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139071.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139071.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104619.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104619.1" } ] } }, { "isoform_ac": "A0ABI0NQK8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4/entry#A0ABI0NQK8-1", "sequence": { "sequence": "MNIYLLQTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLGHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQNAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFNGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYSLNKTQMDGMSFLPILKGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSERWNLQYCEFDDQEVFVEVYNLTADPHQLNNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNHGSVRTRRFSKHLL", "length": 495, "header": "tr|A0ABI0NQK8-1|A0ABI0NQK8_BOVIN Computationally mapped isoform of N-acetylglucosamine-6-sulfatase OS=Bos taurus OX=9913 GN=GNS PE=3 SV=1 CANONICAL=A0ABI0NJH4-1" }, "locus": { "chromosome": "5", "start_pos": 49101027, "end_pos": 49065190, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154210.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154210.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105651.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105651.1" } ] } }, { "isoform_ac": "A0ABI0P2D0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4/entry#A0ABI0P2D0-1", "sequence": { "sequence": "MRLLSLAPDRPRRGGPRHLTSGSPALLLLLLGGCLGVSGAAKSSRRPNVVLLLADDQDEVLGGMYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLGHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQNAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFNGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYSLNKTQMDGMSFLPILKGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSERWNLQYCEFDDQEVFVEVYNLTADPHQLNNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNHGSVRTRRFSKHLL", "length": 532, "header": "tr|A0ABI0P2D0-1|A0ABI0P2D0_BOVIN Computationally mapped isoform of N-acetylglucosamine-6-sulfatase OS=Bos taurus OX=9913 GN=GNS PE=3 SV=1 CANONICAL=A0ABI0NJH4-1" }, "locus": { "chromosome": "5", "start_pos": 49101027, "end_pos": 49053978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137392.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137392.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106972.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106972.1" } ] } }, { "isoform_ac": "F1MXZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4/entry#F1MXZ0-1", "sequence": { "sequence": "MRLLSLAPDRPRRGGPRHLTSGSPALPPPPPLLLLLLLLGGCLGVSGAAKSSRRPNVVLLLADDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLGHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQNAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFNGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYSLNKTQMDGMSFLPILKGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSERWNLQYCEFDDQEVFVEVYNLTADPHQLNNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNHGSVRTRRFSKHLL", "length": 560, "header": "tr|F1MXZ0-1|A0ABI0NJH4_BOVIN Computationally mapped isoform of N-acetylglucosamine-6-sulfatase OS=Bos taurus OX=9913 GN=GNS PE=3 SV=1 CANONICAL=A0ABI0NJH4-1" }, "locus": { "chromosome": "5", "start_pos": 49101027, "end_pos": 49053978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023218.6", "url": "https://www.ensembl.org/id/ENSBTAT00000023218.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023218.3", "url": "https://www.ensembl.org/id/ENSBTAP00000023218.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-2022857", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022857", "resource": "Reactome", "description": "Keratan sulfate degradation" }, { "id": "R-BTA-432720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432720", "resource": "Reactome", "description": "Lysosome Vesicle Biogenesis" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A524-1", "protein_name": "N-acetylglucosamine-6-sulfatase", "gene_name": "GNS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRLLPLASGGPRRGSPRHLPSCSPALLLLLCGCLGVSRVAAADSRRPNVVLLLADDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIEEPNTFPAILRSVCGYQTFFAGKYLNEYGAPDAGGLAHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQNTFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFNGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTTKMLVANIDLGPTILDIAGYNLNKTQMDGMSFLPILKGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSHLWNLQYCEFDDQEVFVEVYNLTADPHQINNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGREEGRMRS", "length": 535 }, "evidence": [ { "id": "A0ABI0NJH4", "url": "https://omabrowser.org/oma/group/A0ABI0NJH4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1NI04-1", "protein_name": "N-acetylglucosamine-6-sulfatase", "gene_name": "GNS", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRSALAALARGLALAALLVLSPAQAARQRPNVVLILTDDQDVFLGGMTPMKKTNALIAQMGVTFSNAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKLWQKIQEPNTFPALLKSMCGYQTFFAGKYLNEYGAEDAGGVSHVPPGWSFWYALEKNSKYYNYTLSVNGKARRHGENYSVDYLTDVLANMSLDFLEYKSNFEPFFMMISTPAPHSPWTAAPQYKNDFLNVSAPRNSNFNIHGKNKHWLIRQAKTPMTNSSIQFLDDAYRKRWQTLLSVDDLVEKLVKKLEIHGELDNTYIFYTSDNGFHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTNKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPLLRGDKNVTWRSDFLVEYQGEGYNGSDPTCPGLGPGVTHCFPDCVCEDSYNNTYACVRTMSTSWDLQYCEFDDREVFVEVYNLTADPHQINNIAKTIDQEILEKMNYRLMMLQSCSGATCRTPGVFDPGYRFDPRLMFSNHGVRARRFSTRSLPSI", "length": 538 }, "evidence": [ { "id": "A0ABI0NJH4", "url": "https://omabrowser.org/oma/group/A0ABI0NJH4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P15586-1", "protein_name": "N-acetylglucosamine-6-sulfatase", "gene_name": "GNS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLLPLAPGRLRRGSPRHLPSCSPALLLLVLGGCLGVFGVAAGTRRPNVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPILRGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYNLTADPDQITNIAKTIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNRGSVRTRRFSKHLL", "length": 552 }, "evidence": [ { "id": "A0ABI0NJH4", "url": "https://omabrowser.org/oma/group/A0ABI0NJH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BFR4-1", "protein_name": "N-acetylglucosamine-6-sulfatase", "gene_name": "Gns", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLPSAAGPRPGRPRRLPALLLLPLLGGCLGLVGAARRPNVLLLLTDDQDAELGGMTPLKKTKALIGEKGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKAWQKIQEPYTFPAILKSVCGYQTFFAGKYLNEYGAPDAGGLEHIPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANLSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQKAFQNVIAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIRFLDDAFRRRWQTLLSVDDLVEKLVKRLDSTGELDNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVSNIDLGPTILDLAGYDLNKTQMDGMSLLPILKGDRNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTLSSLWNLQYCEFDDQEVFVEVYNITADPDQITNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDLRLMFNSHGSVRTRRFSKHPL", "length": 544 }, "evidence": [ { "id": "A0ABI0NJH4", "url": "https://omabrowser.org/oma/group/A0ABI0NJH4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-acetylglucosamine-6-sulfatase activity", "id": "GO:0008449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008449", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "azurophil granule", "id": "GO:0042582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042582", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycosaminoglycan metabolic process", "id": "GO:0030203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030203", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan catabolic process", "id": "GO:0030200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030200", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-1638032", "name": "GNS:Ca2+ cleaves sulfate from GlcNAc-6-sulfate units of keratan sulfate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2104995" ], "output_participant_list": [ "R-ALL-2105012" ], "enzyme_list": [ "A0ABI0NJH4-1" ], "evidence": [ { "id": "R-BTA-1638032", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1638032" } ] }, { "id": "R-BTA-432706", "name": "trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane, cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P84080-1", "A0ABI0NJH4-1", "F1MZ33-1", "P05689-1", "A0A3Q1LUG9-1", "Q2NKW0-1" ], "evidence": [ { "id": "R-BTA-432706", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432706" } ] }, { "id": "R-BTA-432707", "name": "trans-Golgi Network Lysosomal Vesicle Scission", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NJH4-1", "F1MZ33-1", "P05689-1", "A0A3Q1LUG9-1", "Q2NKW0-1" ], "evidence": [ { "id": "R-BTA-432707", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432707" } ] }, { "id": "R-BTA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, azurophil granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O77834-1", "Q29451-1", "P07514-1", "A0JNA3-1", "Q32PF2-1", "Q3MI05-1", "F1MUP9-1", "H7BWW2-1", "Q08DD1-1", "Q2KIM0-1", "Q3ZBH0-1", "F1MU24-1", "A0AAA9U1E9-1", "A0ABI0NJH4-1", "F1N144-1", "F1N5H2-1", "P80189-1", "P46196-1", "A7YWG4-1", "E1BPI3-1", "A0AAA9SWY4-1", "A0A3Q1LUG9-1", "F1MGY9-1", "G3X757-1", "A0A3Q1NDQ7-1", "Q2KJ64-1", "Q3ZCI9-1", "E1B725-1" ], "evidence": [ { "id": "R-BTA-6798751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798751" } ] }, { "id": "R-BTA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19120-1", "P68401-1", "P80227-1", "A0JNA3-1", "F1MMD5-1", "Q32PF2-1", "Q3SZH7-1", "A0AAA9S4U4-1", "A0AAA9S9V5-1", "P07688-1", "O46414-1", "P25326-1", "P80177-1", "Q0VCM4-1", "Q3SWY3-1", "Q3SYU2-1", "F1MHT1-1", "F1MMR6-1", "A0ABI0NJH4-1", "A0AAA9RV00-1", "A0ABI0P3F2-1", "P05689-1", "P46196-1", "P52176-1", "P62935-1", "P68103-1", "Q17QB3-1", "Q3T0Q4-1", "Q27970-1", "A0A452DJA8-1", "E1BNY9-1", "A0A3Q1LMV5-1", "A0A3Q1LTT9-1", "A0AAA9SYX5-1", "A1A4J1-1", "E1BB52-1", "F1MQ78-1", "G3X757-1", "P00432-1", "Q76LV2-1", "A0A140T8A5-1", "A0A3Q1LR63-1", "A0A3Q1NDQ7-1", "Q3T0A3-1", "Q3ZBD7-1", "Q58DK5-1", "Q3SZ62-1", "Q3T0V9-1", "Q3ZCI9-1" ], "evidence": [ { "id": "R-BTA-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6800434" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2104995", "participant_name": "GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]", "crossref": [ { "id": "63851", "database": "ChEBI", "url": "" }, { "id": "G80016QC", "database": "GlyTouCan", "url": "" }, { "id": "ZINC000096085298", "database": "ZINC", "url": "" }, { "id": "ZINC000096085297", "database": "ZINC", "url": "" }, { "id": "G06780", "database": "KEGG Glycan", "url": "" } ] }, { "participant_id": "R-ALL-2105012", "participant_name": "GlcNAc-Gal-GlcNAc(S)-Gal [lysosomal lumen]", "crossref": [ { "id": "ZINC000096085299", "database": "ZINC", "url": "" }, { "id": "63852", "database": "ChEBI", "url": "" }, { "id": "G13033", "database": "KEGG Glycan", "url": "" }, { "id": "ZINC000096085300", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T8A5", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] } ] }, { "uniprot_ac": "A0A3Q1LMV5", "gene_name": "LOC281806", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] } ] }, { "uniprot_ac": "A0A3Q1LR63", "gene_name": "HK3", "activity": [ { "ec_number": "2.7.1.1", "activity": "D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR63" } ] }, { "ec_number": "2.7.1.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR63" } ] } ] }, { "uniprot_ac": "A0A3Q1LTT9", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTT9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LTT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTT9" } ] } ] }, { "uniprot_ac": "A0A3Q1LUG9", "gene_name": "TXNDC5", "activity": [ { "ec_number": "5.3.4.1", "activity": "Catalyzes the rearrangement of -S-S- bonds in proteins.", "evidence": [ { "id": "A0A3Q1LUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUG9" } ] }, { "ec_number": "5.3.4.1", "activity": "", "evidence": [ { "id": "A0A3Q1LUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUG9" } ] } ] }, { "uniprot_ac": "A0A3Q1NDQ7", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A3Q1NDQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDQ7" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A3Q1NDQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDQ7" } ] } ] }, { "uniprot_ac": "A0A452DJA8", "gene_name": "PNP", "activity": [ { "ec_number": "2.4.2.1", "activity": "adenosine + phosphate = alpha-D-ribose 1-phosphate + adenine.", "evidence": [ { "id": "A0A452DJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DJA8" } ] }, { "ec_number": "2.4.2.1", "activity": "", "evidence": [ { "id": "A0A452DJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DJA8" } ] } ] }, { "uniprot_ac": "A0AAA9RV00", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAA9RV00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV00" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAA9RV00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV00" } ] } ] }, { "uniprot_ac": "A0AAA9S4U4", "gene_name": "ALDOC", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0AAA9S4U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4U4" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0AAA9S4U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4U4" } ] } ] }, { "uniprot_ac": "A0AAA9S9V5", "gene_name": "CANT1", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S9V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9V5" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "A0AAA9S9V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9V5" } ] } ] }, { "uniprot_ac": "A0AAA9SWY4", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] } ] }, { "uniprot_ac": "A0AAA9SYX5", "gene_name": "KCMF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9SYX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYX5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9SYX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYX5" } ] } ] }, { "uniprot_ac": "A0AAA9U1E9", "gene_name": "GALNS", "activity": [ { "ec_number": "3.1.6.4", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.", "evidence": [ { "id": "A0AAA9U1E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1E9" } ] }, { "ec_number": "3.1.6.4", "activity": "", "evidence": [ { "id": "A0AAA9U1E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1E9" } ] } ] }, { "uniprot_ac": "A0ABI0NJH4", "gene_name": "GNS", "activity": [ { "ec_number": "3.1.6.14", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.", "evidence": [ { "id": "A0ABI0NJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ] }, { "ec_number": "3.1.6.14", "activity": "", "evidence": [ { "id": "A0ABI0NJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ] } ] }, { "uniprot_ac": "A0ABI0P3F2", "gene_name": "DDX3Y", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] } ] }, { "uniprot_ac": "A0JNA3", "gene_name": "IMPDH1", "activity": [ { "ec_number": "1.1.1.205", "activity": "IMP + NAD(+) + H2O = XMP + NADH + H(+).", "evidence": [ { "id": "A0JNA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNA3" } ] }, { "ec_number": "1.1.1.205", "activity": "", "evidence": [ { "id": "A0JNA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNA3" } ] } ] }, { "uniprot_ac": "A1A4J1", "gene_name": "PFKL", "activity": [ { "ec_number": "2.7.1.11", "activity": "beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+).", "evidence": [ { "id": "A1A4J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4J1" } ] }, { "ec_number": "2.7.1.11", "activity": "", "evidence": [ { "id": "A1A4J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4J1" } ] } ] }, { "uniprot_ac": "A7YWG4", "gene_name": "GGH", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "A7YWG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YWG4" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "A7YWG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YWG4" } ] } ] }, { "uniprot_ac": "E1B725", "gene_name": "GLA", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "E1B725", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B725" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BNY9", "gene_name": "HUWE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] } ] }, { "uniprot_ac": "E1BPI3", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] } ] }, { "uniprot_ac": "F1MGY9", "gene_name": "AGA", "activity": [ { "ec_number": "3.5.1.26", "activity": "N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+).", "evidence": [ { "id": "F1MGY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGY9" } ] }, { "ec_number": "3.5.1.26", "activity": "", "evidence": [ { "id": "F1MGY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGY9" } ] } ] }, { "uniprot_ac": "F1MHT1", "gene_name": "AGL", "activity": [ { "ec_number": "2.4.1.25", "activity": "Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] }, { "ec_number": "3.2.1.33", "activity": "Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] }, { "ec_number": "3.2.1.33", "activity": "", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] }, { "ec_number": "2.4.1.25", "activity": "", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMR6", "gene_name": "CTSD", "activity": [ { "ec_number": "3.4.23.5", "activity": "Specificity similar to, but narrower than, that of pepsin A. Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin.", "evidence": [ { "id": "F1MMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMR6" } ] }, { "ec_number": "3.4.23.5", "activity": "", "evidence": [ { "id": "F1MMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMR6" } ] } ] }, { "uniprot_ac": "F1MQ78", "gene_name": "ALOX5", "activity": [ { "ec_number": "1.13.11.34", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O.", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] }, { "ec_number": "1.13.11.12", "activity": "(9Z,12Z,15Z)-octadecatrienoate + O2 = (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate.", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] }, { "ec_number": "1.13.11.34", "activity": "", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] }, { "ec_number": "1.13.11.12", "activity": "", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] } ] }, { "uniprot_ac": "F1MU24", "gene_name": "PYGB", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "F1MU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU24" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "F1MU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU24" } ] } ] }, { "uniprot_ac": "F1MUP9", "gene_name": "VAT1", "activity": [ { "ec_number": "1.6.5.5", "activity": "2 1,2-naphthoquinone + NADPH + H(+) = 2 1,2-naphthosemiquinone + NADP(+).", "evidence": [ { "id": "F1MUP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUP9" } ] }, { "ec_number": "1.6.5.5", "activity": "", "evidence": [ { "id": "F1MUP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUP9" } ] } ] }, { "uniprot_ac": "F1MZ33", "gene_name": "DNASE2", "activity": [ { "ec_number": "3.1.22.1", "activity": "Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products.", "evidence": [ { "id": "F1MZ33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZ33" } ] }, { "ec_number": "3.1.22.1", "activity": "", "evidence": [ { "id": "F1MZ33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZ33" } ] } ] }, { "uniprot_ac": "F1N144", "gene_name": "ADA2", "activity": [ { "ec_number": "3.5.4.4", "activity": "2'-deoxyadenosine + H2O + H(+) = 2'-deoxyinosine + NH4(+).", "evidence": [ { "id": "F1N144", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N144" } ] }, { "ec_number": "3.5.4.4", "activity": "", "evidence": [ { "id": "F1N144", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N144" } ] } ] }, { "uniprot_ac": "F1N5H2", "gene_name": "FUCA2", "activity": [ { "ec_number": "3.2.1.51", "activity": "an alpha-L-fucoside + H2O = L-fucose + an alcohol.", "evidence": [ { "id": "F1N5H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5H2" } ] }, { "ec_number": "3.2.1.51", "activity": "", "evidence": [ { "id": "F1N5H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5H2" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "H7BWW2", "gene_name": "HEXB", "activity": [ { "ec_number": "3.2.1.52", "activity": "Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.", "evidence": [ { "id": "H7BWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H7BWW2" } ] }, { "ec_number": "3.2.1.52", "activity": "", "evidence": [ { "id": "H7BWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H7BWW2" } ] } ] }, { "uniprot_ac": "O46414", "gene_name": "FTH1", "activity": [ { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "O46414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46414" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "O46414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46414" } ] } ] }, { "uniprot_ac": "O77834", "gene_name": "PRDX6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "2.3.1.23", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] } ] }, { "uniprot_ac": "P00432", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "P00432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00432" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "P00432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00432" } ] } ] }, { "uniprot_ac": "P05689", "gene_name": "CTSZ", "activity": [ { "ec_number": "3.4.18.1", "activity": "Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.", "evidence": [ { "id": "P05689", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05689" } ] }, { "ec_number": "3.4.18.1", "activity": "", "evidence": [ { "id": "P05689", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05689" } ] } ] }, { "uniprot_ac": "P07514", "gene_name": "CYB5R3", "activity": [ { "ec_number": "1.6.2.2", "activity": "2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+).", "evidence": [ { "id": "P07514", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07514" } ] }, { "ec_number": "1.6.2.2", "activity": "", "evidence": [ { "id": "P07514", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07514" } ] } ] }, { "uniprot_ac": "P07688", "gene_name": "CTSB", "activity": [ { "ec_number": "3.4.22.1", "activity": "Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.", "evidence": [ { "id": "P07688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07688" } ] }, { "ec_number": "3.4.22.1", "activity": "", "evidence": [ { "id": "P07688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07688" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P25326", "gene_name": "CTSS", "activity": [ { "ec_number": "3.4.22.27", "activity": "Similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.", "evidence": [ { "id": "P25326", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25326" } ] }, { "ec_number": "3.4.22.27", "activity": "", "evidence": [ { "id": "P25326", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25326" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P52176", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "P52176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52176" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "P52176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52176" } ] } ] }, { "uniprot_ac": "P62935", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P62935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62935" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P62935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62935" } ] } ] }, { "uniprot_ac": "P68103", "gene_name": "EEF1A1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P68103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68103" } ] } ] }, { "uniprot_ac": "P68401", "gene_name": "PAFAH1B2P68402", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "P68401", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68401" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "P68401", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68401" } ] } ] }, { "uniprot_ac": "P80177", "gene_name": "MIF", "activity": [ { "ec_number": "5.3.2.1", "activity": "3-phenylpyruvate = enol-phenylpyruvate.", "evidence": [ { "id": "P80177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80177" } ] }, { "ec_number": "5.3.3.12", "activity": "L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.", "evidence": [ { "id": "P80177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80177" } ] }, { "ec_number": "5.3.2.1", "activity": "", "evidence": [ { "id": "P80177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80177" } ] }, { "ec_number": "5.3.3.12", "activity": "", "evidence": [ { "id": "P80177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80177" } ] } ] }, { "uniprot_ac": "P80189", "gene_name": "LYS", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P80189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80189" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P80189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80189" } ] } ] }, { "uniprot_ac": "P80227", "gene_name": "APEH", "activity": [ { "ec_number": "3.4.19.1", "activity": "Internal cleavage of oxidized and glycated proteins.", "evidence": [ { "id": "P80227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80227" } ] }, { "ec_number": "3.4.19.1", "activity": "", "evidence": [ { "id": "P80227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80227" } ] } ] }, { "uniprot_ac": "P84080", "gene_name": "ARF1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P84080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P84080" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P84080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P84080" } ] } ] }, { "uniprot_ac": "Q08DD1", "gene_name": "ARSA", "activity": [ { "ec_number": "3.1.6.8", "activity": "an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + H2O = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + sulfate + H(+).", "evidence": [ { "id": "Q08DD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DD1" } ] }, { "ec_number": "3.1.6.8", "activity": "", "evidence": [ { "id": "Q08DD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DD1" } ] } ] }, { "uniprot_ac": "Q0VCM4", "gene_name": "PYGL", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "Q0VCM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCM4" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "Q0VCM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCM4" } ] } ] }, { "uniprot_ac": "Q17QB3", "gene_name": "ASAH1", "activity": [ { "ec_number": "3.5.1.23", "activity": "an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid.", "evidence": [ { "id": "Q17QB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QB3" } ] }, { "ec_number": "3.5.1.23", "activity": "", "evidence": [ { "id": "Q17QB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QB3" } ] }, { "ec_number": "3.5.1.-", "activity": "", "evidence": [ { "id": "Q17QB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QB3" } ] } ] }, { "uniprot_ac": "Q27970", "gene_name": "CAPN1", "activity": [ { "ec_number": "3.4.22.52", "activity": "Broad endopeptidase specificity.", "evidence": [ { "id": "Q27970", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27970" } ] }, { "ec_number": "3.4.22.52", "activity": "", "evidence": [ { "id": "Q27970", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27970" } ] } ] }, { "uniprot_ac": "Q29451", "gene_name": "MAN2B1", "activity": [ { "ec_number": "3.2.1.24", "activity": "Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.", "evidence": [ { "id": "Q29451", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29451" } ] }, { "ec_number": "3.2.1.24", "activity": "", "evidence": [ { "id": "Q29451", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29451" } ] } ] }, { "uniprot_ac": "Q2KIM0", "gene_name": "FUCA1", "activity": [ { "ec_number": "3.2.1.51", "activity": "an alpha-L-fucoside + H2O = L-fucose + an alcohol.", "evidence": [ { "id": "Q2KIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIM0" } ] }, { "ec_number": "3.2.1.51", "activity": "", "evidence": [ { "id": "Q2KIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIM0" } ] } ] }, { "uniprot_ac": "Q2KJ64", "gene_name": "ARG1", "activity": [ { "ec_number": "3.5.3.1", "activity": "L-arginine + H2O = urea + L-ornithine.", "evidence": [ { "id": "Q2KJ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ64" } ] }, { "ec_number": "3.5.3.1", "activity": "", "evidence": [ { "id": "Q2KJ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ64" } ] } ] }, { "uniprot_ac": "Q2NKW0", "gene_name": "BLOC1S1", "activity": [ { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q2NKW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKW0" } ] } ] }, { "uniprot_ac": "Q32PF2", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "Q32PF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PF2" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "Q32PF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PF2" } ] } ] }, { "uniprot_ac": "Q3MI05", "gene_name": "CTSA", "activity": [ { "ec_number": "3.4.16.5", "activity": "Release of a C-terminal amino acid with broad specificity.", "evidence": [ { "id": "Q3MI05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MI05" } ] }, { "ec_number": "3.4.16.5", "activity": "", "evidence": [ { "id": "Q3MI05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MI05" } ] }, { "ec_number": "3.4.16.-", "activity": "", "evidence": [ { "id": "Q3MI05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MI05" } ] } ] }, { "uniprot_ac": "Q3SWY3", "gene_name": "IMPDH2", "activity": [ { "ec_number": "1.1.1.205", "activity": "IMP + NAD(+) + H2O = XMP + NADH + H(+).", "evidence": [ { "id": "Q3SWY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY3" } ] }, { "ec_number": "1.1.1.205", "activity": "", "evidence": [ { "id": "Q3SWY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY3" } ] } ] }, { "uniprot_ac": "Q3SYU2", "gene_name": "EEF2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q3SYU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYU2" } ] } ] }, { "uniprot_ac": "Q3SZ62", "gene_name": "PGAM1", "activity": [ { "ec_number": "5.4.2.11", "activity": "(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate.", "evidence": [ { "id": "Q3SZ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZ62" } ] }, { "ec_number": "5.4.2.4", "activity": "(2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+).", "evidence": [ { "id": "Q3SZ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZ62" } ] }, { "ec_number": "5.4.2.4", "activity": "", "evidence": [ { "id": "Q3SZ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZ62" } ] }, { "ec_number": "5.4.2.11", "activity": "", "evidence": [ { "id": "Q3SZ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZ62" } ] } ] }, { "uniprot_ac": "Q3SZH7", "gene_name": "LTA4H", "activity": [ { "ec_number": "3.3.2.6", "activity": "leukotriene A4 + H2O = leukotriene B4.", "evidence": [ { "id": "Q3SZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZH7" } ] }, { "ec_number": "3.4.11.4", "activity": "Release of the N-terminal residue from a tripeptide.", "evidence": [ { "id": "Q3SZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZH7" } ] }, { "ec_number": "3.3.2.6", "activity": "", "evidence": [ { "id": "Q3SZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZH7" } ] } ] }, { "uniprot_ac": "Q3T0A3", "gene_name": "CFD", "activity": [ { "ec_number": "3.4.21.46", "activity": "Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.", "evidence": [ { "id": "Q3T0A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0A3" } ] }, { "ec_number": "3.4.21.46", "activity": "", "evidence": [ { "id": "Q3T0A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0A3" } ] } ] }, { "uniprot_ac": "Q3T0Q4", "gene_name": "NME2", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "Q3T0Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Q4" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "Q3T0Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Q4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "Q3T0Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Q4" } ] }, { "ec_number": "2.7.13.3", "activity": "", "evidence": [ { "id": "Q3T0Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Q4" } ] } ] }, { "uniprot_ac": "Q3T0V9", "gene_name": "DERA", "activity": [ { "ec_number": "4.1.2.4", "activity": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.", "evidence": [ { "id": "Q3T0V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0V9" } ] }, { "ec_number": "4.1.2.4", "activity": "", "evidence": [ { "id": "Q3T0V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0V9" } ] } ] }, { "uniprot_ac": "Q3ZBD7", "gene_name": "GPI", "activity": [ { "ec_number": "5.3.1.9", "activity": "alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate.", "evidence": [ { "id": "Q3ZBD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBD7" } ] }, { "ec_number": "5.3.1.9", "activity": "", "evidence": [ { "id": "Q3ZBD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBD7" } ] }, { "ec_number": "5.1.3.-", "activity": "", "evidence": [ { "id": "Q3ZBD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBD7" } ] } ] }, { "uniprot_ac": "Q3ZBH0", "gene_name": "CCT2", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q3ZBH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBH0" } ] } ] }, { "uniprot_ac": "Q3ZCI9", "gene_name": "CCT8", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q3ZCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCI9" } ] } ] }, { "uniprot_ac": "Q58DK5", "gene_name": "ALAD", "activity": [ { "ec_number": "4.2.1.24", "activity": "2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+).", "evidence": [ { "id": "Q58DK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DK5" } ] }, { "ec_number": "4.2.1.24", "activity": "", "evidence": [ { "id": "Q58DK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DK5" } ] } ] }, { "uniprot_ac": "Q76LV2", "gene_name": "HSP90AA1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q76LV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q76LV2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q76LV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q76LV2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" }, { "id": "PF00884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 384, "start_aa": "Pro", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.6.14", "ec_name": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.", "evidence": [ { "id": "3.1.6.14", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.6.14" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 117, "end_pos": 119 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 480, "end_pos": 482 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BND1-1", "uniprot_ac": "E1BND1", "uniprot_id": "E1BND1_BOVIN", "mass": { "chemical_mass": 46335.0, "monoisotopic_mass": 46335.0 }, "refseq": {}, "gene_names": [ { "name": "KIN", "type": "recommended", "evidence": [ { "id": "E1BND1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ] } ], "protein_names": [ { "name": "DNA/RNA-binding protein KIN17", "type": "recommended", "evidence": [ { "id": "E1BND1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND1/entry#names_and_taxonomy" } ] }, { "name": "Binding to curved DNA", "type": "synonym", "evidence": [ { "id": "E1BND1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo. Binds via its C-terminal domain to RNA in vitro.", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1#function" }, { "database": "UniProtKB", "id": "ARBA00054469", "url": "https://www.uniprot.org/uniprotkb/ARBA00054469#function" }, { "database": "UniProtKB", "id": "A0AAA9S931", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S931#function" }, { "database": "UniProtKB", "id": "A0AAA9TN82", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN82#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KIN", "url": "https://www.uniprot.org/uniprotkb/E1BND1", "locus": { "chromosome": "13", "start_pos": 16147256, "end_pos": 16109948, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013925", "url": "https://www.ensembl.org/id/ENSBTAG00000013925" } ] } } ], "crossref": [ { "id": "E1BND1", "url": "https://alphafold.ebi.ac.uk/entry/E1BND1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013925", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013925", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "519670", "url": "https://www.ncbi.nlm.nih.gov/gene/519670", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BND1", "url": "https://www.orthodb.org/?gene=E1BND1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12805", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12805", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12805:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12805:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18131", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18131", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25095", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25095", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8876725", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S931", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S931", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S931-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S931-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TN82", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TN82-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BND1-1", "url": "https://www.uniprot.org/uniprotkb/E1BND1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIQEQVRRGLEGKEQEVPVFTELSRENDEEKVTFNLNKGACSSGAASSKSSSLGPSALKTIGTVASVKRKESSQSSAPSKEKKKKKSALDEIMEIEEEKKRTARTDYWLQPEIIVKIITKKLGEKYHKKKGIVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETAEPSMHMRWNKVNDRKMTQAQRSGNEDE", "length": 400, "header": "tr|E1BND1-1|E1BND1_BOVIN Isoform 1 of DNA/RNA-binding protein KIN17 OS=Bos taurus OX=9913 GN=KIN PE=3 SV=2 CANONICAL=E1BND1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S931-1", "url": "https://www.uniprot.org/uniprotkb/E1BND1/entry#A0AAA9S931-1", "sequence": { "sequence": "MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIQEQVRRGLEGKEQEVPVFTELSRENDEEKVTFNLNKGACSSGAASSKSSSLGPSALKTIGTVASVKRKESSQSSAPSKEKKKKKSALDEIMEIEEEKKRTARTDYWLQPEIIVKIITKKLGEKYHKKKGIVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETVKNPPAVSET", "length": 382, "header": "tr|A0AAA9S931-1|E1BND1_BOVIN Computationally mapped isoform of DNA/RNA-binding protein KIN17 OS=Bos taurus OX=9913 GN=KIN PE=3 SV=2 CANONICAL=E1BND1-1" }, "locus": { "chromosome": "13", "start_pos": 16131554, "end_pos": 16109989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087941.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087941.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080432.2", "url": "https://www.ensembl.org/id/ENSBTAP00000080432.2" } ] } }, { "isoform_ac": "A0AAA9TN82-1", "url": "https://www.uniprot.org/uniprotkb/E1BND1/entry#A0AAA9TN82-1", "sequence": { "sequence": "MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIQEQVRRGLEGKEQEVPVFTELSRENDEEKVTFNLNKGACSSGAASSKSSSLGPSALKTIGTVASVKRKESSQSSAPSKEKKKKKSALDEIMEIEEEKKRTARTDYWLQPEIIVKIITKKLGEKYHKKKGIVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRVEGIQYEDISKLA", "length": 392, "header": "tr|A0AAA9TN82-1|E1BND1_BOVIN Computationally mapped isoform of DNA/RNA-binding protein KIN17 OS=Bos taurus OX=9913 GN=KIN PE=3 SV=2 CANONICAL=E1BND1-1" }, "locus": { "chromosome": "13", "start_pos": 16133179, "end_pos": 16109989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098090.2", "url": "https://www.ensembl.org/id/ENSBTAT00000098090.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098728.2", "url": "https://www.ensembl.org/id/ENSBTAP00000098728.2" } ] } }, { "isoform_ac": "E1BND1-1", "url": "https://www.uniprot.org/uniprotkb/E1BND1/entry#E1BND1-1", "sequence": { "sequence": "MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIQEQVRRGLEGKEQEVPVFTELSRENDEEKVTFNLNKGACSSGAASSKSSSLGPSALKTIGTVASVKRKESSQSSAPSKEKKKKKSALDEIMEIEEEKKRTARTDYWLQPEIIVKIITKKLGEKYHKKKGIVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETAEPSMHMRWNKVNDRKMTQAQRSGNEDE", "length": 400, "header": "tr|E1BND1-1|E1BND1_BOVIN Isoform 1 of DNA/RNA-binding protein KIN17 OS=Bos taurus OX=9913 GN=KIN PE=3 SV=2 CANONICAL=E1BND1-1" }, "locus": { "chromosome": "13", "start_pos": 16147254, "end_pos": 16109989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061405.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061405.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053570.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053570.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8876725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876725", "resource": "Reactome", "description": "Protein methylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "E1BND1", "url": "https://www.uniprot.org/uniprotkb/E1BND1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BND1", 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40591.0, "monoisotopic_mass": 40591.0 }, "refseq": {}, "gene_names": [ { "name": "LOC132342088", "type": "recommended", "evidence": [ { "id": "A0AAA9SK09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK09" } ] } ], "protein_names": [ { "name": "NADP-dependent oxidoreductase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0AAA9SK09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK09/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SK09", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK09" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132342088", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK09", "locus": {} } ], "crossref": [ { "id": "cd19108", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19108", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR018170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11732", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11732", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SA80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SA80-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SK09", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SK09-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLKSQKVKLNDGHFIPVLGFGTAVPPEVPRSEALEATKFAIEVGFRHIDCARVYQTEEQVGQAIRSKIADGTVKREDIFYTSKLWCTFLRPDLVQPALEKSLKDLQLDYVDLYLIHFPVSMKPGEELLPKDENGKIILDSVDLCRTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSRDIVLVAYSALGSQRIKGWVNQNHPVLLEDPVLCAIAKKNKQTPALVALRYQIQRGVVVLIKSFNKKRIKENIQTPALVALRYQIQRGVVVLIKSFNKKRIKENIQVFDFELSPEDMKAIDGIHRNIRYNEILFGVDHPDYPFSEEY", "length": 355, "header": "tr|A0AAA9SK09-1|A0AAA9SK09_BOVIN Isoform 1 of NADP-dependent oxidoreductase domain-containing protein OS=Bos taurus OX=9913 GN=LOC132342088 PE=3 SV=1 CANONICAL=A0AAA9SK09-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SA80-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK09/entry#A0AAA9SA80-1", "sequence": { "sequence": "MDLKSQKVKLNDGHFIPVLGFGTAVPPEVPRSEALEATKFAIEVGFRHIDCARVYQTEEQVGQAIRSKIADGTVKREDIFYTSKLWCTFLRPDLVQPALEKSLKDLQLDYVDLYLIHFPVSMKPGEELLPKDENGKIILDSVDLCRTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSRDIVLVAYSALGSQRIKGWVNQNHPVLLEDPVLCAIAKKNKQTPALVALRYQIQRGVVVLIKSFNKKRIKENIQVFDFELSPEDMKAIDGIHRNIRYNEILFGVDHPDYPFSEEY", "length": 323, "header": "tr|A0AAA9SA80-1|A0AAA9SK09_BOVIN Computationally mapped isoform of NADP-dependent oxidoreductase domain-containing protein OS=Bos taurus OX=9913 GN=LOC132342088 PE=3 SV=2 CANONICAL=A0AAA9SK09-1" }, "locus": { "chromosome": "13", "start_pos": 43363473, "end_pos": 43289239, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134009.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134009.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082084.2", "url": "https://www.ensembl.org/id/ENSBTAP00000082084.2" } ] } }, { "isoform_ac": "A0AAA9SK09-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK09/entry#A0AAA9SK09-1", "sequence": { "sequence": "MDLKSQKVKLNDGHFIPVLGFGTAVPPEVPRSEALEATKFAIEVGFRHIDCARVYQTEEQVGQAIRSKIADGTVKREDIFYTSKLWCTFLRPDLVQPALEKSLKDLQLDYVDLYLIHFPVSMKPGEELLPKDENGKIILDSVDLCRTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSRDIVLVAYSALGSQRIKGWVNQNHPVLLEDPVLCAIAKKNKQTPALVALRYQIQRGVVVLIKSFNKKRIKENIQTPALVALRYQIQRGVVVLIKSFNKKRIKENIQVFDFELSPEDMKAIDGIHRNIRYNEILFGVDHPDYPFSEEY", "length": 355, "header": "tr|A0AAA9SK09-1|A0AAA9SK09_BOVIN Isoform 1 of NADP-dependent oxidoreductase domain-containing protein OS=Bos taurus OX=9913 GN=LOC132342088 PE=3 SV=1 CANONICAL=A0AAA9SK09-1" }, "locus": { "chromosome": "13", "start_pos": 43363473, "end_pos": 43289239, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118461.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118461.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084259.2", "url": "https://www.ensembl.org/id/ENSBTAP00000084259.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SK09", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9SK09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK09" }, { "id": "PF00248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NADP-dependent oxidoreductase", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 282, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 198, "end_pos": 200 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614840", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614840", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR46756", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46756", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46756:SF9", "url": 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"A0AAA9TH53-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TM87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TM87-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PSY9", "url": "https://www.uniprot.org/uniprotkb/F6PSY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PSY9-1", "url": "https://www.uniprot.org/uniprotkb/F6PSY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETVQEKFKESMDTTKPTKNLPLKKIPCKASAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPSKFCVERLSQGRYRVGEKILFIRGLHGCDYVSIAKAKQTLKMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPVQSKSPTLKDMNPDNYLVVSASYKAKKEIK", "length": 331, "header": "tr|A0AAA9TM87-1|A0AAA9TM87_BOVIN Isoform 1 of Growth arrest specific 2 OS=Bos taurus OX=9913 GN=GAS2 PE=3 SV=1 CANONICAL=A0AAA9TM87-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SH41-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM87/entry#A0AAA9SH41-1", "sequence": { "sequence": "MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETVQEKFKESMDTTKPTKNLPLKKIPCKASAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPSKFCVERLSQGRYRVGEKILFIRMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPVQSKSPTLKDMNPDNYLVVSASYKAKKEIK", "length": 313, "header": "tr|A0AAA9SH41-1|A0AAA9TM87_BOVIN Computationally mapped isoform of Growth arrest specific 2 OS=Bos taurus OX=9913 GN=GAS2 PE=3 SV=2 CANONICAL=A0AAA9TM87-1" }, "locus": { "chromosome": "29", "start_pos": 22183953, "end_pos": 22045798, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099511.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099511.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081820.2", "url": "https://www.ensembl.org/id/ENSBTAP00000081820.2" } ] } }, { "isoform_ac": "A0AAA9TH53-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM87/entry#A0AAA9TH53-1", "sequence": { "sequence": "MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETVQEKFKESMDTTKPTKNLPLKKIPCKASAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGLGSGGQ", "length": 141, "header": "tr|A0AAA9TH53-1|A0AAA9TM87_BOVIN Computationally mapped isoform of Growth arrest specific 2 OS=Bos taurus OX=9913 GN=GAS2 PE=3 SV=1 CANONICAL=A0AAA9TM87-1" }, "locus": { "chromosome": "29", "start_pos": 22183953, "end_pos": 22143394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096582.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096582.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097563.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097563.1" } ] } }, { "isoform_ac": "A0AAA9TM87-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM87/entry#A0AAA9TM87-1", "sequence": { "sequence": "MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETVQEKFKESMDTTKPTKNLPLKKIPCKASAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPSKFCVERLSQGRYRVGEKILFIRGLHGCDYVSIAKAKQTLKMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPVQSKSPTLKDMNPDNYLVVSASYKAKKEIK", "length": 331, "header": "tr|A0AAA9TM87-1|A0AAA9TM87_BOVIN Isoform 1 of Growth arrest specific 2 OS=Bos taurus OX=9913 GN=GAS2 PE=3 SV=1 CANONICAL=A0AAA9TM87-1" }, "locus": { "chromosome": "29", "start_pos": 22183953, "end_pos": 22045798, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089227.2", "url": "https://www.ensembl.org/id/ENSBTAT00000089227.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098358.2", "url": "https://www.ensembl.org/id/ENSBTAP00000098358.2" } ] } }, { "isoform_ac": "F6PSY9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM87/entry#F6PSY9-1", "sequence": { "sequence": "MDVEGIFKQGRLNEGLGLENYRIHVGDAAAAAIYGGKEITAETFMEKLDNGALLCQLAETVQEKFKESMDTTKPTKNLPLKKIPCKASAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPSKFCVERLSQGRYRVGEKILFIRMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPVQSKSPTLKDMNPDNYLVVSASYKAKKEIK", "length": 300, "header": "tr|F6PSY9-1|F6PSY9_BOVIN Computationally mapped isoform of Growth arrest specific 2 OS=Bos taurus OX=9913 GN=GAS2 PE=3 SV=1 CANONICAL=A0AAA9TM87-1" }, "locus": { "chromosome": "29", "start_pos": 22224588, "end_pos": 22045798, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028855.8", "url": "https://www.ensembl.org/id/ENSBTAT00000028855.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028855.7", "url": "https://www.ensembl.org/id/ENSBTAP00000028855.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614840", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614840", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TM87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TM87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TM87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM87" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 156, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0AAA9TM87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM87" }, { "id": "PS51460", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51460" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GAR", "eco_id": "ECO_0000259", "start_pos": 197, "end_pos": 288, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMZ8-1", "uniprot_ac": "E1BMZ8", "uniprot_id": "E1BMZ8_BOVIN", "mass": { "chemical_mass": 193361.0, "monoisotopic_mass": 193361.0 }, "refseq": { "ac": "NP_001192964", "name": "5'-3' exoribonuclease 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192964" }, "gene_names": [ { "name": "XRN1", "type": "recommended", "evidence": [ { "id": "E1BMZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ] }, { "name": "XRN1", "type": "synonym", "evidence": [ { "id": "NP_001192964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192964" } ] } ], "protein_names": [ { "name": "5'-3' exoribonuclease 1", "type": "recommended", "evidence": [ { "id": "E1BMZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8/entry#names_and_taxonomy" } ] }, { "name": "3.1.13.-", "type": "synonym", "evidence": [ { "id": "E1BMZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8/entry#names_and_taxonomy" } ] }, { "name": "5'-3' exoribonuclease 1", "type": "synonym", "evidence": [ { "id": "NP_001192964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192964" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "XRN1", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8", "locus": { "chromosome": "1", "start_pos": 126701959, "end_pos": 126593243, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011524", "url": "https://www.ensembl.org/id/ENSBTAG00000011524" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011524", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011524", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18673", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18673", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540834", "url": "https://www.ncbi.nlm.nih.gov/gene/540834", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540834", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540834", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VASWPWF", "url": "https://omabrowser.org/oma/group/VASWPWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMZ8", "url": "https://www.orthodb.org/?gene=E1BMZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12341", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12341", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12341:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12341:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17846", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17846", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-450385", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-450385", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-450513", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-450513", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192964", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192964", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SJZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWW4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMZ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEEKIKKAIEKGETLPAEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKDKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYITILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEAKSYKEKKKSKGQENSICWAALDKNGEEVVTSKDNVEEEMEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWFYPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTSDDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWFDSNTEFTYPSPWPEKFPPVERCCARYKIISLDAWRIDISKNNITKVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENMMLEILVNAESDELSVENIASSVLGKSVFVNWPHLEEARVVGVSDGETKFYLEEPPGTQKLYLGRTAPPSKVVHLGDKEQCNWTKEVQGISEYYLRRKGIIINETSAVVYGQLLTGRKYQINQNGEVRLEKQWSKQVLPFVYQTIVKDIRAFDSRFSSIKTLDDLFPPRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEIEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFRLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVNHYSSNSSVSSGHLGGLNHSPQSLFVPTQVPARDDDEFCNIWQSLQGSGKVQHFQPLLQEKGAVLPQEISQVTQHHKTGFNDNSVKPRKHEPHRKFKEECKSPKTESRSQKMSNRQPNPGIENFLASLNISKESEIQSSHHEEPPSEEHLSPQSFAMKGTRMLKEILKIDSSDSMDHKNEMKQFGNEVTVSSSRRDEYGSSSQPKQNKKLTSYMNKPHSASEYHNVQSMDSVCWPTGQIPPMSTPVTELSRICSLVGMPQPDFSFLRTPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAFFAIQQLGSLGVNFPLPPPVFPSYPPAVPPGTIPPVFPQPTGWDHYGSNLALGAANIMPSSSHLFGSVPWGPPMPVPGKPFHHTSYAGTMPMAGGMPAGVHNQFIPLQVTKKRVANKKNFENKEAQSYQVTPLHTSQSASSDVTKGIPQETSSASLPSSQIPQPASSFQVAAASPGHSMPHQKSAPSSSRRKSRKLAVNFGVSKPSE", "length": 1703, "header": "tr|E1BMZ8-1|E1BMZ8_BOVIN Isoform 1 of 5'-3' exoribonuclease 1 OS=Bos taurus OX=9913 GN=XRN1 PE=3 SV=2 CANONICAL=E1BMZ8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SJZ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8/entry#A0AAA9SJZ2-1", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEEKIKKAIEKGETLPAEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKDKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYITILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEAKSYKEKKKSKGQENSICWAALDKNGEEVVTSKDNVEEEMEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWFYPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTSDDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWFDSNTEFTYPSPWPEKFPPVERCCARYKIISLDAWRIDISKNNITKVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENMMLEILVNAESDELSVENIASSVLGKSVFVNWPHLEEARVVGVSDGETKFYLEEPPGTQKLYLGRTAPPSKVVHLGDKEQCNWTKEVQGISEYYLRRKGIIINETSAVVYGQLLTGRKYQINQNGEVRLEKQWSKQVLPFVYQTIVKDIRAFDSRFSSIKTLDDLFPPRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEIEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFRLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVNHYSSNSSVSSGHLGGLNHSPQSLFVPTQVPARDDDEFCNIWQSLQGSGKVQHFQPLLQEKGAVLPQEISQVTQHHKTGFNDNSVKPRKHEPHRKFKEECKSPKTESRSQKMSNRQAFGGPAKCNIKLLKRNENSEVSENQKVVTGYPSGVDKPNPGIENFLASLNISKESEIQSSHHEEPPSEEHLSPQSFAMKGTRMLKEILKIDSSDSMDHKNEMKQFGNEVTVSSSRRDEYGSSSQPKQNKKLTSYMNKPHSASEYHNVQSMDSVCWPTGQIPPMSTPVTELSRICSLVGMPQPDFSFLRTPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAFFAIQQLGSLGVNFPLPPPVFPSYPPAVPPGTIPPVFPQPTGWDHYGSNLALGAANIMPSSSHLFGSVPWGPPMPVPGKPFHHTSYAGTMPMAGGMPAGVHNQFIPLQVTKKRVANKKNFENKEAQSYQVTPLHTSQSASSDVTKGIPQETSSASLPSSQIPQPASSFQVAAASPGHSMPHQKSAPSSSRRKSRKLAVNFGVSKPSE", "length": 1740, "header": "tr|A0AAA9SJZ2-1|E1BMZ8_BOVIN Computationally mapped isoform of 5'-3' exoribonuclease 1 OS=Bos taurus OX=9913 GN=XRN1 PE=3 SV=1 CANONICAL=E1BMZ8-1" }, "locus": { "chromosome": "1", "start_pos": 126700955, "end_pos": 126593309, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093517.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093517.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082902.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082902.1" } ] } }, { "isoform_ac": "A0AAA9TWW4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8/entry#A0AAA9TWW4-1", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEEKIKKAIEKGETLPAEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKDKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYITILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEAKSYKEKKKSKGQENSICWAALDKNGEEVVTSKDNVEEEMEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWFYPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTSDDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWFDSNTEFTYPSPWPEKFPPVERCCARYKIISLDAWRIDISKNNITKVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENMMLEILVNAESDELSVENIASSVLGKSVFVNWPHLEEARVVGVSDGETKFYLEEPPGTQKLYLGRTAPPSKVVHLGDKEQCNWTKEVQGISEYYLRRKGIIINETSAVVYGQLLTGRKYQINQNGEVRLEKQWSKQVLPFVYQTIVKDIRAFDSRFSSIKTLDDLFPPRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEIEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFRLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVNHYSSNSSVSSGHLGGLNHSPQSLFVPTQVPARDDDEFCNIWQSLQGSGKVQHFQPLLQEKGAVLPQEISQVTQHHKTGFNDNSVKPRKHEPHRKFKEECKSPKTESRSQKMSNRQAFGGPAKCNIKLLKRNENSEVSENQKVVTGYPSGVDKPNPGIENFLASLNISKESEIQSSHHEEPPSEEHLSPQSFAMKGTRMLKEILKIDSSDSMDHKNEMKQFGNEVTVSSSRRDEYGSSSQPKQNKKLTSYMNKPHSASEYHNVQSMDSVCWPTGQIPPMSTPVTELSRICSLVGMPQPDFSFLRTPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAFFAIQQLGSLGVNFPLPPPVFPSYPPAVPPGTIPPVFPQPTANIMPSSSHLFGSVPWGPPMPVPGKPFHHTSYAGTMPMAGGMPAGVHNQFIPLQVTKKRVANKKNFENKEAQSYQVTPLHTSQSASSDVTKGIPQETSSASLPSSQIPQPASSFQVAAASPGHSMPHQKSAPSSSRRKSRKLAVNFGVSKPSE", "length": 1727, "header": "tr|A0AAA9TWW4-1|E1BMZ8_BOVIN Computationally mapped isoform of 5'-3' exoribonuclease 1 OS=Bos taurus OX=9913 GN=XRN1 PE=3 SV=1 CANONICAL=E1BMZ8-1" }, "locus": { "chromosome": "1", "start_pos": 126700955, "end_pos": 126593309, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126252.2", "url": "https://www.ensembl.org/id/ENSBTAT00000126252.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101955.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101955.1" } ] } }, { "isoform_ac": "E1BMZ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8/entry#E1BMZ8-1", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEEKIKKAIEKGETLPAEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKDKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYITILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEAKSYKEKKKSKGQENSICWAALDKNGEEVVTSKDNVEEEMEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWFYPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTSDDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWFDSNTEFTYPSPWPEKFPPVERCCARYKIISLDAWRIDISKNNITKVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENMMLEILVNAESDELSVENIASSVLGKSVFVNWPHLEEARVVGVSDGETKFYLEEPPGTQKLYLGRTAPPSKVVHLGDKEQCNWTKEVQGISEYYLRRKGIIINETSAVVYGQLLTGRKYQINQNGEVRLEKQWSKQVLPFVYQTIVKDIRAFDSRFSSIKTLDDLFPPRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEIEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFRLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVNHYSSNSSVSSGHLGGLNHSPQSLFVPTQVPARDDDEFCNIWQSLQGSGKVQHFQPLLQEKGAVLPQEISQVTQHHKTGFNDNSVKPRKHEPHRKFKEECKSPKTESRSQKMSNRQPNPGIENFLASLNISKESEIQSSHHEEPPSEEHLSPQSFAMKGTRMLKEILKIDSSDSMDHKNEMKQFGNEVTVSSSRRDEYGSSSQPKQNKKLTSYMNKPHSASEYHNVQSMDSVCWPTGQIPPMSTPVTELSRICSLVGMPQPDFSFLRTPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAFFAIQQLGSLGVNFPLPPPVFPSYPPAVPPGTIPPVFPQPTGWDHYGSNLALGAANIMPSSSHLFGSVPWGPPMPVPGKPFHHTSYAGTMPMAGGMPAGVHNQFIPLQVTKKRVANKKNFENKEAQSYQVTPLHTSQSASSDVTKGIPQETSSASLPSSQIPQPASSFQVAAASPGHSMPHQKSAPSSSRRKSRKLAVNFGVSKPSE", "length": 1703, "header": "tr|E1BMZ8-1|E1BMZ8_BOVIN Isoform 1 of 5'-3' exoribonuclease 1 OS=Bos taurus OX=9913 GN=XRN1 PE=3 SV=2 CANONICAL=E1BMZ8-1" }, "locus": { "chromosome": "1", "start_pos": 126700955, "end_pos": 126593309, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015318.6", "url": "https://www.ensembl.org/id/ENSBTAT00000015318.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015318.4", "url": "https://www.ensembl.org/id/ENSBTAP00000015318.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:540834", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540834", "resource": "KEGG Pathway" }, { "id": "R-BTA-450385", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-450385", "resource": "Reactome", "description": "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" }, { "id": "R-BTA-450513", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-450513", "resource": "Reactome", "description": "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YLM3-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "XRN1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGVPKFYRWISERYPCLSQVLKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISEDKIFADIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKALEKGEILPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGITVYLSGHETPGEGEHKIMEFIRSEKAKPHHDPNTRHCLYGLDADLIMLGLTTHEAHFALLREEVRFGGKKSQRACAPEETTFHLLHLSLMREYIDYEFSPVKDKISFDYDIEKIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYRTYMAILPELGGYINENGHLNLKRFEKYLTRLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGIAAEEARNNKQKKRKAQENSLCLAALEKNEDEVVTSKTVLEDEPEDDDLFETEFRQYKRTYYMTKMGIEVVSDDFLADQAECYVQAIQWILHYYYHGVQSWSWYYPYHYAPYLSDIRNISELKIQFELGKPFMPFEQLLAVLPAASKDLLPRCYQHLMVSQDSPIIEYYPLDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMESCNKCLKEEEKRRNVHSACLMYWYDKDAEFPYTSPWPEKFPAIERCHTRYKTIPLDAWHVEITHNKITKINKSALYFCGFPTLKHIKHKFYLKKSGVQVFQQSSHGENMMLEILTDENSKEQTVENVASSVLGKVVFVNWPHLEEARVVAVSDGETKFYLEEPHGTQKLYMGNAVPPTKVTFVGDKEQSMWLKEVQGVSEHYQRRKGIIIHETSVVVYAQLLTGNRYQLNQNGQVYLEKQWSKQALPFVYQTVVKDIKAFDSRFSNIRTLDDLFPPGSTAFMLGSPYYGCMGEVQDSRDVIPEGRIRVVFSIPCEPQLDRLIQNQHKYSVKYNPAYILASRLGVSGYLVSRFTGSIFIGRGSKKNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAVEQLLAEYLERVPELFSYIAKNSQEDIFYEDDIWPGEDENGAEKVQEIVAWLKAHPVSALSRSSCDLQILDAAIVEKIEEEIEKCKQRKSNKKVRVTVKPHLLYRPLEQQNGVVPDRDAEYRLFDRVVNVRENFSVPVGLRGTIIGIKGASRETDVLFEVLFDEEFLGGLTIRCSPARGYRLPSSALINLSHGVRSEMGNQKLTAIVKPQPAVNNYNSYASDLSSVCSQKVHLGGLNHSPRSLFVPTQQLNGRQHYNLRAENQGTSNSPHKGSFLSSNQKNKAQNKQDDEFCSIWQSLQGSGKSHHVQQNIHEKGAVLPQEIKLGSGNQFYKPGFNDGSFRSQQRKQEPYKKFKEDSRFTRGESQPHNKIPNKQNFAGVNKHNVKLLKRNESVPVIQKAASDSPCTSGKKDSELESLLASLKISKENEVQTSSKEARATNEEHLSPQSFAMKGTQMLKEILKIDGSDLETRNEAKSHVNDVPASPGRQDCHGAALQYRQTKKMAAYMNNPHSTGGPQSTPALGTGGHPFVGPQPTLSTPVSELSRICSLVGMSQPDFSFIKTPQTMTVCHIKLSNGLLVHGPQCHSEAEAKEKAALSALQRLSSVGVNLPFPPPVFPNYQPLGVPVPPGSLPPVFSQPPANIMPPSSHMFGPVSWGTPVPIHGKHYYPGSYPGNVSLAGTIPVGSHNQFIPLQVTKKRAASKKNFEFKEFQSSPQAAPLKNEQPVSSDHIQQDSSSAPLKSPQAAQSTVSFQDNAATPSVPRNKSAPNTSSKRKPRKLAVNFGTPKSAE", "length": 1770 }, "evidence": [ { "id": "E1BMZ8", "url": "https://omabrowser.org/oma/group/E1BMZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ABN8-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "Xrn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKEKITFKYDIEKIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYIAILPELGGYINESGHLNLPRFERYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGAAAEEAKSCKDKRKVKGQENSLSWAALDKREGEGVASRDNFEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDEFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPSASKTLLPTCYQHLMTSEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDSDTEFTYSSPWPEKFPAIERCSTRYKIISLDAWRVDINKNKITRVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENMMLEITVNAEPDELSIENIASSVLGKSVFVNWPHLEEARVVAVSDGETKFYMEEPPGTQKVYLGKTAPPCKVIQLSDKEQSNWTKEIQGISEQYLRRKGIMINETSAVVYAQLLTGRRYQVNQNGEVRLEKQWSKQSLPFVYQTIVKDVRAFDSRFSNIKTLDDLFPPRSVVFMLGTPYYGCTGEVQDSGDVITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLAGRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKRVGSEWMYSSAAEQLLAEYIERAPELFSYIAQNSQEDVFYEDDIWPGESESGAEKVQEIITWLKGHPVSTLSRSSCDLHILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLFRPLEQQHGAIPDRDAEFRLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRCETGNQKLTAIVKPQPAVSHCSVNSSVSSGHMGGLNHSPQSLFLPTQVPTKGDDEFCNIWQSLQGSGKIQHLQPTVQEKGAVLPQEISQVTESHKSGFNDHSVRHQQRKHDPHRKFKEEYKSPKAECQNQKLSNKQTSGASARCNIKLLKRNESPGTSEAQKVVTSYPNAVHKPHSGIESFLASLNISKESEVQLPHGEPPDEAHLSPQSFAMKGTRMLKEILKIDSPDTTDSKNDVKKFDNEVMVSSSRRDEHGPSSHPKPTSHVSQPHSTNEYQSVDSVCWPGHMPPVSTPVTELSRICSLVGMPQPDFSFLRTTQTMTVCQVKLSNGLLVHGPQCHSESEAKERAALFALQQLGSLGVNFPLPPPIFTNYPPAVPPGAVPPVFPQPTANMMPSSSHLFGSVPWRPPVPVPGNAYHYPSYPATMPLAGGMPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPLQTNKPGSSEATRMTPQEGSPASSASSQATQPVSSHVETASQGHVVSHQRSAPSSSRRKSRKLAVNFSVSKPSE", "length": 1719 }, "evidence": [ { "id": "E1BMZ8", "url": "https://omabrowser.org/oma/group/E1BMZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1JJR3-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "pcm", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGVPKFFRYISERYPCLSELAREHCIPEFDNLYLDMNGIVHNCSHPDDNNIHFHLEEEQIFQEIFNYVDKLFYLIKPQRLFFLSVDGVAPRAKMNQQRSRRFRTAREAEQQEAKAAQRGELREHERFDSNCITPGTEFMVRLQEGLRAFLKTKISTDPLWQRCTVILSGQEAPGEGEHKIMDYIRYMKTQPDYDPNTRHCLYGLDADLIILGLCTHELHFVVLREEVKFGRNVKRTSVEETRFFLLHLGLLREYLELEFDALRTDEHKLDIAQLIDDWVLMGFLVGNDFIPHLPCLHISSNALPLLYRTYIGIYPTLGGNINENGKLNLRRLQIFISALTEVELDHFKEHADDLKYMNNKSEAFDMDVGEITESQNLDSDLGALINKSMLLYDDDSEEDCSDENAVLLKEFQNYKRNFYRNKFKRDPNDELIEELCHHYVNALQWVLDYYYRGVQSWDWYYPFHYTPFISDLKNIEQVEIAFHMGTPFLPFQQLLAVLPAASAKLLPVAYHDLMLLPTSPLAEFYPLEFESDLNGKKHDWEAVVLIPFIDEGRLLAAMLPCEAQLSLEERERNRHGPMYVYKYSTVAQGPMPAYPPLRALPVLYCTEVAKWSHEIAVNLPYSVCIELPNAARTVFFPGFPTMQHLPFDFELRNDRVKVFEQVSRNQNIVLKPRKRQLEDTLTAVASQYLGKVIHVGWPHLVKAIVVRVATRDQRVDSEGITLNDSRRFDSECKALQEHFINRMGIQFANYDVLVYVRTFAGNSTEFRDKGALMVRDSWSSSVTGYPAQGVVADLTVWERMRKNFLNVEHYFPVGSTIFLITDPYYGSEGTVQDPRLAYTNGRIQVSIMVRPEPKVNAARQLQEERDRDYLSTFQVCNLLRISGRTLGRLSGTVWVVLGPRRQKMENVTKHNIGLQLKYPRQNEERAGYCFRTNNQWYYSSLAVDLMRNYCQRYPDVIDFFGDSNDRAEFVFEQDVFPNAVGHRRVEELANWVRQQPHMKVERISCGSKTVCRETIELLIAAVDDLRSLPVKHVKLQVKPHLLIKPNVTLPDVYRSKRPVRLFDRVVIVRTIYMVPVGTKGTVIGIHPVTDPNPVRLECVHAVDTFCKVLFDSPVPNCNNIHGIAEDRVYKVPEIALVIIKTDEEGKKQNDCELPVRDPQPNQAQDEPVRATSSRYVTAAGSTSVPITMKTQISDEFVKTRSDPIARTDSYKPSSEPKPVPVPEQITNWRERVSTPTNKPQPAPNNWRINRSSSRQQGGSIFVAPPTKTPDAAASTASTAFTAASSATLTPLDQTLALMSVLGVGEDQSSPPLQEAVQQQRPPLLQQQRAPFPGQMPNLPKPPLFWQQEAQKQEALQQEAQQQEAQKKQQQAHAQMEPERINSQHFYRSGQTGAALNQPPLGAPSKRQWHEWVHPRMQHANAFHAGVNNGYQMRPKKNIAAQSTFNNNVHMHLQQPYYPNQQQQQQQQQPLQLTEINNAPPRYSTIQDFVPIQAYRPKKLNRVQPAGRQDVDATKNPSRSPVLQQPTNETIDTKASSSLPVQSAGEQVIGLMQTLEIKQPAASQSESDGVSTGSANAPTATTSSQAVNRRKHRVPRIGAKFDLEYILPDSPHPT", "length": 1613 }, "evidence": [ { "id": "E1BMZ8", "url": "https://omabrowser.org/oma/group/E1BMZ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F1Q4U5-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "xrn1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDEDVHFRISEEKIFADIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEEKIKKALEKGEVLPTEARFDSNCITPGTDFMARLQEQLKYFVHNKLSTDKTWQGVNVYLSGHETPGEGEHKIMEFIRSESTKPGHNPNTRHCLYGLDADLIMLGLTSHEPHFSLLREEVRFGGKKSQKRITAPEETTFHLLHLSLMREYIDYEFSELRKKISFEYDLERIIDDWVLMGFLVGNDFIPHLPHLHINHDALPLLYRTYINVLPSLGGYLNENGHLNLTHFEKYLEKLSDFDREHFSEVFVDLKWFESKVGNKYVNEAAGLAAEEADGRDLKKSKSSDDSLCLAALDGVRDSHSTAGRAEGAEEDGEDDDMFETEFRQYKRTYYMTKMGVEVVSDEFLANQAKCYVEGIQWILHYYYHGVQSWSWYYPYHYAPFLSDVRNISGLSLTFDLAKPFMPFEQLLAVLPSASKDLLPQCYQHLMTSLSSPIVEYYPQDFKTDLNGKQQEWEAVVLIPFIDEKCLLAAMEPYTHNLTPSEKARNRHTECAVYCYDKDLDYPYNSPDPQIFPNIVHCHARQTPVPMDAWRVSPDHVRCRIDRGALYFCGFPTLQHIRHKFYKKKSGVMVFQQSSRGENMILDILPSHEMVQVEEVAALVLGRSLFVNWPHLMEARVVAVSDGETKFSLEEPAGSQVLYMENNPPPTKVSRVTDKEQKDWVKEVQGLTEHFSKRKGIAINETDVLVYGQLLTGRKYVIGQNGKVHLEKQFAKQVLPFPYQTIVKDIKAFDSSLARFKTLEELFPLGTTVFMVGNPYYGAMGEVQDSSDVISEGRVRVVFSVPCEPQLDALIQNQHKYSVKYSPGYVLASRLGITGYLVSRFSGSIFIGRGSKKNPHGEQKVNVGLNLKFNKKNEEVPGYTKRTEKEWLYSAAVEELIAEYLERFSEVFDHVARNSHDDIFYEDDIWPGEDENGVEKVQEIQGWLKTHPVSSISRASCDLQILDAGIVEKIEEELEKTKAKKMNKKVRVTVKPHLLFRPLEQQHGVVPDPDSEYHLFDRVVNVRESFSVPLGLRGTIIGIKGADREAEILYEVIFDEEFAGGLTIRCSPGRGYRLPPSALINLSHGSRKELGSHKLTAIVKPQPSSSSQISNKSQLGGLNHSPRSPFIPTQQQNGRQSFNLRGDTQGNRNSPHKALNQRNQQKGSSNEKEFSNVWQSLQNSAMPQKPPAHWQNNAGKSQMPHQNQLEGQNKQSQGNDTSIKLGLGGNIRLLKRNEDLNTALQGPSNKASTEFEELIANLKISKDPEPPQHEPPKEPKAPSAEPLSPQSFAMKGTLVLKEMLKIDSSGASSSAPDSGGPNAQQQCKRRSSKKLAARINTPQPETAPAAAAAPPPPPPPHPLAGQPPLLPSMATELGRVCMGLRMGPPEFAFLRNRQSLILCQVKLSNGLMVHGPQCQSETEAKEKAALFTLQRLNSLGSFPLPPPIFPGVQQMRPLAPHPSMFGQPGGGFLMPPQGYGPLPWGMQFPHQGQPFFGGTFPGARGPVPSAAGGSHNQFVPLQVTKKRVSGRTKNQESNQAQSGSPYGVQTPAVPPSAPKTPPSTNAHEHAEKPTATTPKTPKQNANPHTPGSASKRKHRKLAVNFEAAKVTD", "length": 1697 }, "evidence": [ { "id": "E1BMZ8", "url": "https://omabrowser.org/oma/group/E1BMZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P22147-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "XRN1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGIPKFFRYISERWPMILQLIEGTQIPEFDNLYLDMNSILHNCTHGNDDDVTKRLTEEEVFAKICTYIDHLFQTIKPKKIFYMAIDGVAPRAKMNQQRARRFRTAMDAEKALKKAIENGDEIPKGEPFDSNSITPGTEFMAKLTKNLQYFIHDKISNDSKWREVQIIFSGHEVPGEGEHKIMNFIRHLKSQKDFNQNTRHCIYGLDADLIMLGLSTHGPHFALLREEVTFGRRNSEKKSLEHQNFYLLHLSLLREYMELEFKEIADEMQFEYNFERILDDFILVMFVIGNDFLPNLPDLHLNKGAFPVLLQTFKEALLHTDGYINEHGKINLKRLGVWLNYLSQFELLNFEKDDIDVEWFNKQLENISLEGERKRQRVGKKLLVKQQKKLIGSIKPWLMEQLQEKLSPDLPDEEIPTLELPKDLDMKDHLEFLKEFAFDLGLFITHSKSKGSYSLKMDLDSINPDETEEEFQNRVNSIRKTIKKYQNAIIVEDKEELETEKTIYNERFERWKHEYYHDKLKFTTDSEEKVRDLAKDYVEGLQWVLYYYYRGCPSWSWYYPHHYAPRISDLAKGLDQDIEFDLSKPFTPFQQLMAVLPERSKNLIPPAFRPLMYDEQSPIHDFYPAEVQLDKNGKTADWEAVVLISFVDEKRLIEAMQPYLRKLSPEEKTRNQFGKDLIYSFNPQVDNLYKSPLGGIFSDIEHNHCVEKEYITIPLDSSEIRYGLLPNAKLGAEMLAGFPTLLSLPFTSSLEYNETMVFQQPSKQQSMVLQITDIYKTNNVTLEDFSKRHLNKVIYTRWPYLRESKLVSLTDGKTIYEYQESNDKKKFGFITKPAETQDKKLFNSLKNSMLRMYAKQKAVKIGPMEAIATVFPVTGLVRDSDGGYIKTFSPTPDYYPLQLVVESVVNEDERYKERGPIPIEEEFPLNSKVIFLGDYAYGGETTIDGYSSDRRLKITVEKKFLDSEPTIGKERLQMDHQAVKYYPSYIVSKNMHLHPLFLSKITSKFMITDATGKHINVGIPVKFEARHQKVLGYARRNPRGWEYSNLTLNLLKEYRQTFPDFFFRLSKVGNDIPVLEDLFPDTSTKDAMNLLDGIKQWLKYVSSKFIAVSLESDSLTKTSIAAVEDHIMKYAANIEGHERKQLAKVPREAVLNPRSSFALLRSQKFDLGDRVVYIQDSGKVPIFSKGTVVGYTTLSSSLSIQVLFDHEIVAGNNFGGRLRTNRGLGLDASFLLNITNRQFIYHSKASKKALEKKKQSNNRNNNTKTAHKTPSKQQSEEKLRKERAHDLLNFIKKDTNEKNSESVDNKSMGSQKDSKPAKKVLLKRPAQKSSENVQVDLANFEKAPLDNPTVAGSIFNAVANQYSDGIGSNLNIPTPPHPMNVVGGPIPGANDVADVGLPYNIPPGFMTHPNGLHPLHPHQMPYPNMNGMSIPPPAPHGFGQPISFPPPPPMTNVSDQGSRIVVNEKESQDLKKFINGKQHSNGSTIGGETKNSRKGEIKPSSGTNSTECQSPKSQSNAADRDNKKDEST", "length": 1528 }, "evidence": [ { "id": "E1BMZ8", "url": "https://omabrowser.org/oma/group/E1BMZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P97789-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "Xrn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKEKITFKYDIEKIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYIAILPELGGYINESGHLNLPRFERYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGAAAEEAKNCKEKRKPKGQENSLSWAALDKSEGEGVASRDNFEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDEFLANQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIRSISTLKIHFELGKPFKPFEQLLAVLPSASKNLLPTCYQHLMTSEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDETRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFTYSSPWPEKFPAIERCCTRYKMISLDAWRVDINKNKITRVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENLMLEISVNAEPDELRIENIASAVLGKAVFVNWPHLEEARVVAVSDGETKFYIEEPPGTQKVYLGKTAPPSKVIQLTDKEQSNWTKEIQGISEQYLRRKGIIINETSAVVYAQLLTGRKYQISQNGEVRLEKQWSKQILPFVYQTIVKDIRAFDSRFSNIKTLDDLFPPRTMVFMLGTPYYGCTGEVQDSGDLITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLAGRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAAEQLLAEYIERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLHILDAAIVEKIEEEVEKCKQRKSNKKVRVTVKPHLMYRPLEQQHGVIPDRDAEFRLFDRVVNVRESFSVPVGLRGTVIGIKGASREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRCETGNQKLTAIVKPQPSVSHCSAAPSGHLGGLNHSPQSPFLPTQVPTKGDDEFCNIWQSLQGAGKTQHLQPTVQEKGAVLPQEISQVTEGHKSGFTDHSVRHQQRKHDSQRKFKEEYKSPKAECQSQKLSSKQTSGGSARCSIKLLKRNESPGTSEAQKVVTSYPNAVHKPPSGIENFLASLNLSKENEAQLPHHGEPPDEADLSPQSFAMKGTRMLKEILKIDSPDTRDSKNDMKKSDNEATVSSRRDERGVSAHPKPTCHMNKPHGTNEFQNVASVDSVCWPGQMPPVSTPVTELSRICSLVGMPQPDFSFLRTTQTMTVCQVKLSNGLLVHGPQCHSESEAKERAALFALQQLGSLGVSFPLPPPIFTNYPPAVPPGAVPPVFTQPTANIMPSSSHLFGSVSWRPPVPVAGNAFHYPSYPGTMPLAGGVPGGVHSQFIPLQVTKKRVANRKNFENKEAQSSQATPLQTNKPGSSEATKMTPQESPPASSSSSQAAQPVSSHVETASQGHVGSQPRSAPSSSKRKSRKLAVNFSVSKPSE", "length": 1719 }, "evidence": [ { "id": "E1BMZ8", "url": "https://omabrowser.org/oma/group/E1BMZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZH2-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "XRN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE", "length": 1706 }, "evidence": [ { "id": "E1BMZ8", "url": "https://omabrowser.org/oma/group/E1BMZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" }, { "name": "histone mRNA catabolic process", "id": "GO:0071044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071044", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" }, { "name": "5'-3' RNA exonuclease activity", "id": "GO:0004534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004534", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" }, { "name": "telomerase RNA binding", "id": "GO:0070034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070034", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ8", "url": "https://www.uniprot.org/uniprotkb/E1BMZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1115, "end_pos": 1117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1171, "end_pos": 1173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1201, "end_pos": 1203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1213, "end_pos": 1215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1324, "end_pos": 1326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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"table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NJF3-1", "uniprot_ac": "A0ABI0NJF3", "uniprot_id": "A0ABI0NJF3_BOVIN", "mass": { "chemical_mass": 109471.0, "monoisotopic_mass": 109471.0 }, "refseq": {}, "gene_names": [ { "name": "VPS35L", "type": "recommended", "evidence": [ { "id": "A0ABI0NJF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3" } ] } ], "protein_names": [ { "name": "VPS35 endosomal protein-sorting factor-like", "type": "recommended", "evidence": [ { "id": "A0ABI0NJF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "VPS35L", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3", "locus": { "chromosome": "25", "start_pos": 17297111, "end_pos": 17158962, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019412", "url": "https://www.ensembl.org/id/ENSBTAG00000019412" } ] } } ], "crossref": [ { "id": "534058", "url": "https://www.ncbi.nlm.nih.gov/gene/534058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13673", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13673", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13673:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13673:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27614", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27614", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SXB0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXB0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBW4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMD0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMD0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRE2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLG2", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLG2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJF3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQV4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQV4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5A6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5A6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5A6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFQEGHSRNRNYKAEFASCRLEAVPLEFGDYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAASADPATLAAAMDSSRKKRDRDDNSIVGSDFEPWASKRGEILARYTTTEKLSINLFMGSEKGKAGTATSAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDNRSVLPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMVRGIGDPLVSVYARAYLCRVGMEVAPHLKESLNKNFFDFLLTFKQIHGDTVQNQLVLQGVELPSYLPLYSPAMDWVFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLGLNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEVFIKHQQEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLAYLINGFIKMVSFGRDFEQQLSFYVEARSMFCNLEPVLVQLIHSVNRLAMETRKVMKGNHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPDHPEHGVLFLVRELLNVVQDYTWEENSDEKIRIYTCVLHLLSAMSQETYLYHVDKVDSNDSLYGGDSKFLAENNKLCETVMAQILEHLKTLAKDEALKRQSSLGLSFFNSILAHGDLRNNRLNQLSVNLWHLAQRHGCVDTRTMVKTLEYIKKQSKQPDMGHLTELALRLPLQTRT", "length": 963, "header": "tr|A0ABI0NJF3-1|A0ABI0NJF3_BOVIN Isoform 1 of VPS35 endosomal protein-sorting factor-like OS=Bos taurus OX=9913 GN=VPS35L PE=3 SV=1 CANONICAL=A0ABI0NJF3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SXB0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3/entry#A0AAA9SXB0-1", "sequence": { "sequence": "MAAFPWHSRNRNYKAEFASCRLEAVPLEFGDYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAASADPATLAAAMDSSRKKRDRDDNSIVGSDFEPWASKRGEILARYTTTEKLSIAKLGPPHLQCQRRFEPGWRSWMTSRRDPKRSC", "length": 168, "header": "tr|A0AAA9SXB0-1|A0ABI0NJF3_BOVIN Computationally mapped isoform of VPS35 endosomal protein-sorting factor-like OS=Bos taurus OX=9913 GN=VPS35L PE=3 SV=1 CANONICAL=A0ABI0NJF3-1" }, "locus": { "chromosome": "25", "start_pos": 17188747, "end_pos": 17159083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120002.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120002.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088709.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088709.1" } ] } }, { "isoform_ac": "A0AAA9TBW4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3/entry#A0AAA9TBW4-1", "sequence": { "sequence": "MAAFPWHSRNRNYKAEFASCRLEAVPLEFGDYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAASADPATLAAAMDSSRKKRDRDDNSIVGSDFEPWASKRGEILARYTTTEKLSINLFMGSEKGKAGTATSAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDNRSVLPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMVRGIGDPLVSVYARAYLCRALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLGLNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEVFIKHQQEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLAYLINGFIKMVSFGRDFEQQLSFYVEARSMFCNLEPVLVQLIHACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPDHPEHGVLFLVRELLNVVQDYTWEENSDEKIRIYTCVLHLLSAMSQETYLYHVDKVDSNDSLYGGDSKFLAENNKLCETVMAQILEHLKTLAKDEALKRQSSLGLSFFNSILAHGDLRNNRLNQLSVNLWHLAQRHGCVDTRTMVKTLEYIKKQSKQPDMGHLTELALRLPLQTRT", "length": 870, "header": "tr|A0AAA9TBW4-1|A0ABI0NJF3_BOVIN Computationally mapped isoform of VPS35 endosomal protein-sorting factor-like OS=Bos taurus OX=9913 GN=VPS35L PE=3 SV=1 CANONICAL=A0ABI0NJF3-1" }, "locus": { "chromosome": "25", "start_pos": 17296648, "end_pos": 17159083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125484.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125484.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094347.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094347.1" } ] } }, { "isoform_ac": "A0AAA9TMD0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3/entry#A0AAA9TMD0-1", "sequence": { "sequence": "MAAFPWHSRNRNYKAEFASCRLEAVPLEFGDYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAASADPATLAAAMDSSRKKRDRDDNSIVGSDFEPWASKRGEILARYTTTEKLSINLFMGSEKGKAGTATSAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDNRSVLPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMVRGIGDPLVSVYARAYLCRVGMEVAPHLKESLNKNFFDFLLTFKQALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLGLNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEVFIKHQQEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLAYLINGFIKMVSFGRDFEQQLSFYVEARSMFCNLEPVLVQLIHSVNRLAMETRKVMKGNHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPDHPEHGVLFLVRELLNVVQDYTWEENSDEKIRIYTCVLHLLSAMSQETYLYHVDKVDSNDSLYGGDSKFLAENNKLCETVMAQILEHLKTLAKDEALKRQSSLGLSFFNSILAHGDLRNNRLNQLSVNLWHLAQRHGCVDTRTMVKTLEYIKKQSKQPDMGHLTELALRLPLQTRT", "length": 922, "header": "tr|A0AAA9TMD0-1|A0ABI0NJF3_BOVIN Computationally mapped isoform of VPS35 endosomal protein-sorting factor-like OS=Bos taurus OX=9913 GN=VPS35L PE=3 SV=1 CANONICAL=A0ABI0NJF3-1" }, "locus": { "chromosome": "25", "start_pos": 17296648, "end_pos": 17159083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113697.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113697.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098395.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098395.1" } ] } }, { "isoform_ac": "A0AAA9TRE2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3/entry#A0AAA9TRE2-1", "sequence": { "sequence": "MAAFPWHSRNRNYKAEFASCRLEAVPLEFGDYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAASADPATLAAAMDSSRKKRDRDDNSIVGSDFEPWASKRGEILARYTTTEKLSINLFMGSEKGKAGTATSAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDNRSVLPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMVRGIGDPLVSVYARAYLCRIHGDTVQNQLVLQGVELPSYLPLYSPAMDWVFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLGLNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEVFIKHQQEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLAYLINGFIKMVSFGRDFEQQLSFYVEARSMFCNLEPVLVQLIHSVNRLAMETRKVMKGNHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPDHPEHGVLFLVRELLNVVQDYTWEENSDEKIRIYTCVLHLLSAMSQETYLYHVDKVDSNDSLYGGDSKFLAENNKLCETVMAQILEHLKTLAKDEALKRQSSLGLSFFNSILAHGDLRNNRLNQLSVNLWHLAQRHGCVDTRTMVKTLEYIKKQSKQPDMGHLTELALRLPLQTRT", "length": 937, "header": "tr|A0AAA9TRE2-1|A0ABI0NJF3_BOVIN Computationally mapped isoform of VPS35 endosomal protein-sorting factor-like OS=Bos taurus OX=9913 GN=VPS35L PE=3 SV=2 CANONICAL=A0ABI0NJF3-1" }, "locus": { "chromosome": "25", "start_pos": 17296648, "end_pos": 17159083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124739.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124739.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101176.2", "url": "https://www.ensembl.org/id/ENSBTAP00000101176.2" } ] } }, { "isoform_ac": "A0AAF6DLG2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3/entry#A0AAF6DLG2-1", "sequence": { "sequence": "MAAFPWHSRNRNYKAEFASCRLEAVPLEFGDYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAASADPATLAAAMDSSRKKRDRDDNSIVGSDFEPWASKRGEILARYTTTEKLSINLFMGSEKGKAGTATSAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDNRSVLPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMVRGIGDPLVSVYARAYLCRVGMEVAPHLKESLNKNFFDFLLTFKQIHGDTVQNQLVLQGVELPSYLPLYSPAMDWVFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLGLNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEVFIKHQQEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLAYLINGFIKMVSFGRDFEQQLSFYVEARSMFCNLEPVLVQLIHSVNRLAMETRKVMKGNHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPDHPEHGVLFLVRELLNVVQDYTWEENSDEKIRIYTCVLHLLSAMSQETYLYHVDKVDSNDSLYGGDSKFLAENNKLCETVMAQILEHLKTLAKDEARILEWVATPSFRGSSFPPQRSSLHLLHLLH", "length": 913, "header": "tr|A0AAF6DLG2-1|A0ABI0NJF3_BOVIN Computationally mapped isoform of VPS35 endosomal protein-sorting factor-like OS=Bos taurus OX=9913 GN=VPS35L PE=3 SV=2 CANONICAL=A0ABI0NJF3-1" }, "locus": { "chromosome": "25", "start_pos": 17293947, "end_pos": 17159083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025864.8", "url": "https://www.ensembl.org/id/ENSBTAT00000025864.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025864.8", "url": "https://www.ensembl.org/id/ENSBTAP00000025864.8" } ] } }, { "isoform_ac": "A0ABI0NJF3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3/entry#A0ABI0NJF3-1", "sequence": { "sequence": "MDFQEGHSRNRNYKAEFASCRLEAVPLEFGDYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAASADPATLAAAMDSSRKKRDRDDNSIVGSDFEPWASKRGEILARYTTTEKLSINLFMGSEKGKAGTATSAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDNRSVLPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMVRGIGDPLVSVYARAYLCRVGMEVAPHLKESLNKNFFDFLLTFKQIHGDTVQNQLVLQGVELPSYLPLYSPAMDWVFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLGLNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEVFIKHQQEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLAYLINGFIKMVSFGRDFEQQLSFYVEARSMFCNLEPVLVQLIHSVNRLAMETRKVMKGNHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPDHPEHGVLFLVRELLNVVQDYTWEENSDEKIRIYTCVLHLLSAMSQETYLYHVDKVDSNDSLYGGDSKFLAENNKLCETVMAQILEHLKTLAKDEALKRQSSLGLSFFNSILAHGDLRNNRLNQLSVNLWHLAQRHGCVDTRTMVKTLEYIKKQSKQPDMGHLTELALRLPLQTRT", "length": 963, "header": "tr|A0ABI0NJF3-1|A0ABI0NJF3_BOVIN Isoform 1 of VPS35 endosomal protein-sorting factor-like OS=Bos taurus OX=9913 GN=VPS35L PE=3 SV=1 CANONICAL=A0ABI0NJF3-1" }, "locus": { "chromosome": "25", "start_pos": 17296648, "end_pos": 17162663, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153907.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153907.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104571.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104571.1" } ] } }, { "isoform_ac": "A0ABI0NQV4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3/entry#A0ABI0NQV4-1", "sequence": { "sequence": "MAAFPWHSRNRNYKAEFASCRLEAVPLEFGDYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAASADPATLAAAMDSSRKKRDRDDNSIVGSDFEPWASKRGEILARYTTTEKLSINLFMGSEKGKAGTATSAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDNRSVLPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMVRGIGDPLVSVYARAYLCRVGMEVAPHLKESLNKNFFDFLLTFKQIHGDTVQNQLVLQGVELPSYLPLYSPAMDWVFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLGLNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEVFIKHQQEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLAYLINGFIKMVSFGRDFEQQLSFYVEARSMFCNLEPVLVQLIHSVNRLAMETRKVMKGNHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPDHPEHGVLFLVRELLNVVQDYTWEENSDEKIRIYTCVLHLLSAMSQETYLYHVDKVDSNDSLYGGDSKFLAENNKLCETVMAQILEHLKTLAKDEALKRQSSLGLSFFNSILAHGDLRNNRLNQLSVNLWHLAQRHGCVDTRTMVR", "length": 933, "header": "tr|A0ABI0NQV4-1|A0ABI0NQV4_BOVIN Computationally mapped isoform of VPS35 endosomal protein-sorting factor-like OS=Bos taurus OX=9913 GN=VPS35L PE=3 SV=1 CANONICAL=A0ABI0NJF3-1" }, "locus": { "chromosome": "25", "start_pos": 17296553, "end_pos": 17159083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153911.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153911.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104741.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104741.1" } ] } }, { "isoform_ac": "A0ABI0P5A6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3/entry#A0ABI0P5A6-1", "sequence": { "sequence": "MSGSRHSRNRNYKAEFASCRLEAVPLEFGDYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAASADPATLAAAMDSSRKKRDRDDNSIVGSDFEPWASKRGEILARYTTTEKLSINLFMGSEKGKAGTATSAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDNRSVLPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMVRGIGDPLVSVYARAYLCRVGMEVAPHLKESLNKNFFDFLLTFKQIHGDTVQNQLVLQGVELPSYLPLYSPAMDWVFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLGLNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEVFIKHQQEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLAYLINGFIKMVSFGRDFEQQLSFYVEARSMFCNLEPVLVQLIHSVNRLAMETRKVMKGNHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPDHPEHGVLFLVRELLNVVQDYTWEENSDEKIRIYTCVLHLLSAMSQETYLYHVDKVDSNDSLYGGDSKFLAENNKLCETVMAQILEHLKTLAKDEALKRQSSLGLSFFNSILAHGDLRNNRLNQLSVNLWHLAQRHGCVDTRTMVKTLEYIKKQSKQPDMGHLTELALRLPLQTRT", "length": 962, "header": "tr|A0ABI0P5A6-1|A0ABI0P5A6_BOVIN Computationally mapped isoform of VPS35 endosomal protein-sorting factor-like OS=Bos taurus OX=9913 GN=VPS35L PE=3 SV=1 CANONICAL=A0ABI0NJF3-1" }, "locus": { "chromosome": "25", "start_pos": 17296648, "end_pos": 17165023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153284.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153284.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106330.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106330.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 846, "end_pos": 848, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 692, "end_pos": 694 }, { "start_pos": 846, "end_pos": 848 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMI4-1", "uniprot_ac": "E1BMI4", "uniprot_id": "E1BMI4_BOVIN", "mass": { "chemical_mass": 48275.0, "monoisotopic_mass": 48275.0 }, "refseq": { "ac": "XP_005212843", "name": "UDP-glucuronic acid decarboxylase 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212843" }, "gene_names": [ { "name": "UXS1", "type": "recommended", "evidence": [ { "id": "E1BMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" } ] }, { "name": "UXS1", "type": "synonym", "evidence": [ { "id": "XP_005212843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212843" } ] } ], "protein_names": [ { "name": "UDP-glucuronic acid decarboxylase 1", "type": "recommended", "evidence": [ { "id": "E1BMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI4/entry#names_and_taxonomy" } ] }, { "name": "4.1.1.35", "type": "synonym", "evidence": [ { "id": "E1BMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI4/entry#names_and_taxonomy" } ] }, { "name": "UDP-glucuronate decarboxylase 1", "type": "synonym", "evidence": [ { "id": "E1BMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI4/entry#names_and_taxonomy" } ] }, { "name": "UDP-glucuronic acid decarboxylase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005212843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212843" } ] } ], "function": [ { "annotation": "Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis. Catalyzes the synthesis of UDP-xylose in two steps: the hydroxyl group of UDP-glucuronic acid is first oxidized using an enzyme-bound NAD(+) as electron acceptor, favoring the decarboxylation yielding a UDP-4-ketoxylose reaction intermediate and a reduced cofactor NADH bound to the catalytic pocket. In the second step, the 4-keto group is reduced resulting in UDP-xylose and the restoration of the enzyme to its NAD(+)-bound form.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LVQ1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVQ1#function" }, { "database": "UniProtKB", "id": "ARBA00094129", "url": "https://www.uniprot.org/uniprotkb/ARBA00094129#function" }, { "database": "UniProtKB", "id": "A0AAA9T394", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T394#function" }, { "database": "UniProtKB", "id": "E1BMI4", "url": "https://www.uniprot.org/uniprotkb/E1BMI4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMI4", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UXS1", "url": "https://www.uniprot.org/uniprotkb/E1BMI4", "locus": { "chromosome": "11", "start_pos": 45778563, "end_pos": 45721196, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005614", "url": "https://www.ensembl.org/id/ENSBTAG00000005614" } ] } } ], "crossref": [ { "id": "E1BMI4", "url": "https://alphafold.ebi.ac.uk/entry/E1BMI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005614", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005614", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05230", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05230", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534788", "url": "https://www.ncbi.nlm.nih.gov/gene/534788", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LVQ1", "url": "https://www.orthodb.org/?gene=A0A3Q1LVQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BMI4", "url": "https://www.orthodb.org/?gene=E1BMI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43078", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43078", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43078:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43078:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11803", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11803", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-173599", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-173599", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1971475", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1971475", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005212843", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212843", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23916", "url": "https://www.rhea-db.org/rhea/23916", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LVQ1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T394", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T394", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T394-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T394-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMI4", "url": "https://www.uniprot.org/uniprotkb/E1BMI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMI4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSQPLLRLVSAVSRRRMKLLLGIALLAYVASVWGNLINMSVLLNRSIQENRELRIESRIEEIIEPLREKIRDLEKSFTQKYPPVKFLSEKDRKRILVTGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQTEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSGSQTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEHTILEFAQLIKNLVGSGSEIQFLSEAQDDPQKRKPDIKKAKLMLGWEPVVPLEEGLNKAIHYFRKELEYQANNQYIPKPKPARIKKGRTRHN", "length": 425, "header": "tr|E1BMI4-1|E1BMI4_BOVIN Isoform 1 of UDP-glucuronic acid decarboxylase 1 OS=Bos taurus OX=9913 GN=UXS1 PE=3 SV=2 CANONICAL=E1BMI4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVQ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMI4/entry#A0A3Q1LVQ1-1", "sequence": { "sequence": "MFKLASSFPMCAVWGNLINMSVLLNRSIQENRELRIESRIEEIIEPLREKIRDLEKSFTQKYPPVKFLSEKDRKRILVTGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQTEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSGSQTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEHTILEFAQLIKNLVGSGSEIQFLSEAQDDPQKRKPDIKKAKLMLGWEPVVPLEEGLNKAIHYFRKELEYQANNQYIPKPKPARIKKGRTRHN", "length": 405, "header": "tr|A0A3Q1LVQ1-1|E1BMI4_BOVIN Computationally mapped isoform of UDP-glucuronic acid decarboxylase 1 OS=Bos taurus OX=9913 GN=UXS1 PE=3 SV=2 CANONICAL=E1BMI4-1" }, "locus": { "chromosome": "11", "start_pos": 45777863, "end_pos": 45722550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085746.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085746.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064733.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064733.2" } ] } }, { "isoform_ac": "A0AAA9T394-1", "url": "https://www.uniprot.org/uniprotkb/E1BMI4/entry#A0AAA9T394-1", "sequence": { "sequence": "MLSQPLLRLVSAVSRRRMKLLLGIALLAYVASVWGNLINMRSIQENRELRIESRIEEIIEPLREKIRDLEKSFTQKYPPVKFLSEKDRKRILVTGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQTEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSGSQTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEHTILEFAQLIKNLVAVRELLASTGCALCHRCPGAPRILSQECLLPTVDQEIRVSDTTRLEWVWLNCVSKMWACPDPHFSQLQCLGWSVLAPSCLLPAWTVGQDRG", "length": 433, "header": "tr|A0AAA9T394-1|E1BMI4_BOVIN Computationally mapped isoform of UDP-glucuronic acid decarboxylase 1 OS=Bos taurus OX=9913 GN=UXS1 PE=3 SV=1 CANONICAL=E1BMI4-1" }, "locus": { "chromosome": "11", "start_pos": 45774779, "end_pos": 45721395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123609.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123609.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090163.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090163.1" } ] } }, { "isoform_ac": "E1BMI4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMI4/entry#E1BMI4-1", "sequence": { "sequence": "MLSQPLLRLVSAVSRRRMKLLLGIALLAYVASVWGNLINMSVLLNRSIQENRELRIESRIEEIIEPLREKIRDLEKSFTQKYPPVKFLSEKDRKRILVTGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQTEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSGSQTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEHTILEFAQLIKNLVGSGSEIQFLSEAQDDPQKRKPDIKKAKLMLGWEPVVPLEEGLNKAIHYFRKELEYQANNQYIPKPKPARIKKGRTRHN", "length": 425, "header": "tr|E1BMI4-1|E1BMI4_BOVIN Isoform 1 of UDP-glucuronic acid decarboxylase 1 OS=Bos taurus OX=9913 GN=UXS1 PE=3 SV=2 CANONICAL=E1BMI4-1" }, "locus": { "chromosome": "11", "start_pos": 45777863, "end_pos": 45721395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007374.6", "url": "https://www.ensembl.org/id/ENSBTAT00000007374.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007374.5", "url": "https://www.ensembl.org/id/ENSBTAP00000007374.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-173599", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-173599", "resource": "Reactome", "description": "Formation of the active cofactor, UDP-glucuronate" }, { "id": "R-BTA-1971475", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1971475", "resource": "Reactome", "description": "Glycosaminoglycan-protein linkage region biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "D-xylose metabolic process", "id": "GO:0042732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042732", "evidence": [ { "database": "UniProtKB", "id": "E1BMI4", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" } ], "pmid": "" }, { "name": "UDP-D-xylose biosynthetic process", "id": "GO:0033320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033320", "evidence": [ { "database": "UniProtKB", "id": "E1BMI4", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BMI4", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "E1BMI4", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BMI4", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "NAD+ binding", "id": "GO:0070403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070403", "evidence": [ { "database": "UniProtKB", "id": "E1BMI4", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" } ], "pmid": "" }, { "name": "UDP-glucuronate decarboxylase activity", "id": "GO:0048040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048040", "evidence": [ { "database": "UniProtKB", "id": "E1BMI4", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23916", "name": "", "equation": "UDP-alpha-D-glucuronate + H(+) = UDP-alpha-D-xylose + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BMI4-1", "A0AAA9RX56-1" ], "evidence": [ { "id": "23916", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23916" } ] }, { "id": "R-BTA-8863761", "name": "UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-8863760" ], "enzyme_list": [ "E1BMI4-1" ], "evidence": [ { "id": "R-BTA-8863761", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8863761" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8863760", "participant_name": "CO2 [Golgi lumen]", "crossref": [ { "id": "HMDB0001967", "database": "HMDB Metabolite", "url": "" }, { "id": "C00011", "database": "COMPOUND", "url": "" }, { "id": "16526", "database": "ChEBI", "url": "" }, { "id": "11533283", "database": "PubChem Substance", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9RX56", "gene_name": "LOC617301", "activity": [ { "ec_number": "4.1.1.35", "activity": "UDP-alpha-D-glucuronate + H(+) = UDP-alpha-D-xylose + CO2.", "evidence": [ { "id": "A0AAA9RX56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX56" } ] }, { "ec_number": "4.1.1.35", "activity": "", "evidence": [ { "id": "A0AAA9RX56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX56" } ] } ] }, { "uniprot_ac": "E1BMI4", "gene_name": "UXS1", "activity": [ { "ec_number": "4.1.1.35", "activity": "UDP-alpha-D-glucuronate + H(+) = UDP-alpha-D-xylose + CO2.", "evidence": [ { "id": "E1BMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" } ] }, { "ec_number": "4.1.1.35", "activity": "", "evidence": [ { "id": "E1BMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" }, { "id": "PF16363", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16363" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NAD(P)-binding", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 391, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI4" }, { "id": "PF11803", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11803" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDP-glucuronate decarboxylase N-terminal", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 83, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.1.1.35", "ec_name": "UDP-alpha-D-glucuronate + H(+) = UDP-alpha-D-xylose + CO2.", "evidence": [ { "id": "4.1.1.35", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.35" }, { "id": "4.1.1.35", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.1.1.35" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 321, "end_pos": 323 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NIZ1-1", "uniprot_ac": "A0ABI0NIZ1", "uniprot_id": "A0ABI0NIZ1_BOVIN", "mass": { "chemical_mass": 110419.0, "monoisotopic_mass": 110419.0 }, "refseq": {}, "gene_names": [ { "name": "LOC112442366", "type": "recommended", "evidence": [ { "id": "A0ABI0NIZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NIZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T6M0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6M0#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0ABI0NIZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1#function" }, { "database": "UniProtKB", "id": "A0ABI0NNH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNH4#function" }, { "database": "UniProtKB", "id": "A0ABI0NPR3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPR3#function" }, { "database": "UniProtKB", "id": "A0ABI0P6K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6K8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC112442366", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "112442366", "url": "https://www.ncbi.nlm.nih.gov/gene/112442366", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF400", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF400", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9T6M0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6M0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NIZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NIZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNH4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPR3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPR3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6K8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6K8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPTIGNVRTVKTHGRRSPEEERTGVRHGSFSGTVDLQGCVHRFHSRGVGMPGPCPEDLVQGCDGGDPREPAVCGSLLLQGIFSTCSEQGLPCSYDMSQIDMIKKLQAKADSGKGEIFQRVMFERAESLESKDFHLRKMQENIDDFDCLRTDDERNDKGLSTSHNKNLTDGRDHHSRSDAENGTFERHGSSFQDESQMMQSEGIIFECSQVVTDVSASGLSSQRTLNVCKGFSHKDENAVMHPSELLPDHETQNKRPYKCNECDITFLQDSELTRHQRIHTGGKPYKCDVCGKAFNQTRKLAIHWRIHTGEKPHKCDVCGKVFKQAAKFLIHWRYHMREKPYKCDVCGKAFSQTANLAVHQRIHTGEKPYKCNVCGKAFNHSANLAVHQRVHTGEKPYKCDVCGKAFNQTAKLGLHQKIHTGEKSYKCDVCGKAFSRTGNLAVHRRVHTGEKPYKCDICGKAFRVTSHLADHRRVHTGEKPYKCNVCDKAFSRAANLTVHWRIHTGEKPYKCDVCGKAFNHTTRLQLHQRIHTGEKPYKCNVCERAFSHTSSLSVHRRLHTGVKPYKCDICGRAFSQTASLALHRSIHTGEKPYKCDVCGKAFNQTAKLRLHRRIHTGEKPYKCCVCGKAFSHTTGLELHQRIHTGEKPYKCNVCDKAFSHSSNLTVHRRLHAGEKPYKCDICGKGFSVSSSLAVHQRVHTGEKPYKCDTCGKAFNQTAKLGLHQKIHTGEKSYKCDVCGKAFSRTGNLTVHRRVHTGEKPYKCDMCGKAFRVSSNLAVHQRVHTGEKPYKCDVCGKAFSQATGLAVHQRIHTGEKPYKCDVCGKAFNHTTRLQLHQRIHTGEKPYKCNVCDKAFISAANLSVHRKLHTGEKPYKCDICGKGFRVSSNLGIHRSVHTGEKPYKCDVCGKAFSHTGNLAVHRRVHTGEKPYKCDVCGKAFSCTGNLAVHRRLHTGEKPYKCDVCGKAFSRTGNLAVHRRLHTGK", "length": 983, "header": "tr|A0ABI0NIZ1-1|A0ABI0NIZ1_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC112442366 PE=3 SV=1 CANONICAL=A0ABI0NIZ1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T6M0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1/entry#A0AAA9T6M0-1", "sequence": { "sequence": "MALKRKISYAQLTFKDVFIDFTPEEWECLDPAQRTLYKDVMVETLGNLLSVDMSQIDMIKKLQAKADSGKGEIFQRVMFERAESLESKDFHLRKMQENIDDFDCLRTDDERNDKGLSTSHNKNLTDGRDHHSRSDAENGTFERHGSSFQDESQMMQSEGIIFECSQVVTDVSASGLSSQRTLNVCKGFSHKDENAVMHPSELLPDHETQNKRPYKCNECDITFLQDSELTRHQRIHTGGKPYKCDVCGKAFNQTRKLAIHWRIHTGEKPHKCDVCGKVFKQAAKFLIHWRYHMREKPYKCDVCGKAFSQTANLAVHQRIHTGEKPYKCNVCGKAFNHSANLAVHQRVHTGEKPYKCDVCGKAFNQTAKLGLHQKIHTGEKSYKCDVCGKAFSRTGNLAVHRRVHTGEKPYKCDICGKAFRVTSHLADHRRVHTGEKPYKCNVCDKAFSRAANLTVHWRIHTGEKPYKCDVCGKAFNHTTRLQLHQRIHTGEKPYKCNVCERAFSHTSSLSVHRRLHTGVKPYKCDICGRAFSQTASLALHRSIHTGEKPYKCDVCGKAFNQTAKLRLHRRIHTGEKPYKCCVCGKAFSHTTGLELHQRIHTGEKPYKCNVCDKAFISAANLSVHRKLHTGEKPYKCDICGKGFRVSSNLGIHRSVHTGEKPYKCDVCGKAFSHTGNLAVHRRVHTGEKPYKCDVCGKAFSCTGNLAVHRRLHTGEKPYKCDVCGKAFSRTGNLAVHRRLHTGK", "length": 743, "header": "tr|A0AAA9T6M0-1|A0ABI0NIZ1_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC112442366 PE=3 SV=2 CANONICAL=A0ABI0NIZ1-1" }, "locus": { "chromosome": "18", "start_pos": 59822809, "end_pos": 59814305, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115571.2", "url": "https://www.ensembl.org/id/ENSBTAT00000115571.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092392.2", "url": "https://www.ensembl.org/id/ENSBTAP00000092392.2" } ] } }, { "isoform_ac": "A0ABI0NIZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1/entry#A0ABI0NIZ1-1", "sequence": { "sequence": "MRPTIGNVRTVKTHGRRSPEEERTGVRHGSFSGTVDLQGCVHRFHSRGVGMPGPCPEDLVQGCDGGDPREPAVCGSLLLQGIFSTCSEQGLPCSYDMSQIDMIKKLQAKADSGKGEIFQRVMFERAESLESKDFHLRKMQENIDDFDCLRTDDERNDKGLSTSHNKNLTDGRDHHSRSDAENGTFERHGSSFQDESQMMQSEGIIFECSQVVTDVSASGLSSQRTLNVCKGFSHKDENAVMHPSELLPDHETQNKRPYKCNECDITFLQDSELTRHQRIHTGGKPYKCDVCGKAFNQTRKLAIHWRIHTGEKPHKCDVCGKVFKQAAKFLIHWRYHMREKPYKCDVCGKAFSQTANLAVHQRIHTGEKPYKCNVCGKAFNHSANLAVHQRVHTGEKPYKCDVCGKAFNQTAKLGLHQKIHTGEKSYKCDVCGKAFSRTGNLAVHRRVHTGEKPYKCDICGKAFRVTSHLADHRRVHTGEKPYKCNVCDKAFSRAANLTVHWRIHTGEKPYKCDVCGKAFNHTTRLQLHQRIHTGEKPYKCNVCERAFSHTSSLSVHRRLHTGVKPYKCDICGRAFSQTASLALHRSIHTGEKPYKCDVCGKAFNQTAKLRLHRRIHTGEKPYKCCVCGKAFSHTTGLELHQRIHTGEKPYKCNVCDKAFSHSSNLTVHRRLHAGEKPYKCDICGKGFSVSSSLAVHQRVHTGEKPYKCDTCGKAFNQTAKLGLHQKIHTGEKSYKCDVCGKAFSRTGNLTVHRRVHTGEKPYKCDMCGKAFRVSSNLAVHQRVHTGEKPYKCDVCGKAFSQATGLAVHQRIHTGEKPYKCDVCGKAFNHTTRLQLHQRIHTGEKPYKCNVCDKAFISAANLSVHRKLHTGEKPYKCDICGKGFRVSSNLGIHRSVHTGEKPYKCDVCGKAFSHTGNLAVHRRVHTGEKPYKCDVCGKAFSCTGNLAVHRRLHTGEKPYKCDVCGKAFSRTGNLAVHRRLHTGK", "length": 983, "header": "tr|A0ABI0NIZ1-1|A0ABI0NIZ1_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC112442366 PE=3 SV=1 CANONICAL=A0ABI0NIZ1-1" }, "locus": { "chromosome": "18", "start_pos": 59838799, "end_pos": 59814305, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138153.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138153.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104275.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104275.1" } ] } }, { "isoform_ac": "A0ABI0NNH4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1/entry#A0ABI0NNH4-1", "sequence": { "sequence": "MAAHQAPPSLGFSSQEHWSGLPLPSPILSAYREVNKDMSQIDMIKKLQAKADSGKGEIFQRVMFERAESLESKDFHLRKMQENIDDFDCLRTDDERNDKGLSTSHNKNLTDGRDHHSRSDAENGTFERHGSSFQDESQMMQSEGIIFECSQVVTDVSASGLSSQRTLNVCKGFSHKDENAVMHPSELLPDHETQNKRPYKCNECDITFLQDSELTRHQRIHTGGKPYKCDVCGKAFNQTRKLAIHWRIHTGEKPHKCDVCGKVFKQAAKFLIHWRYHMREKPYKCDVCGKAFSQTANLAVHQRIHTGEKPYKCNVCGKAFNHSANLAVHQRVHTGEKPYKCDVCGKAFNQTAKLGLHQKIHTGEKSYKCDVCGKAFSRTGNLAVHRRVHTGEKPYKCDICGKAFRVTSHLADHRRVHTGEKPYKCNVCDKAFSRAANLTVHWRIHTGEKPYKCDVCGKAFNHTTRLQLHQRIHTGEKPYKCNVCERAFSHTSSLSVHRRLHTGVKPYKCDICGRAFSQTASLALHRSIHTGEKPYKCDVCGKAFNQTAKLRLHRRIHTGEKPYKCCVCGKAFSHTTGLELHQRIHTGEKPYKCNVCDKAFSHSSNLTVHRRLHAGEKPYKCDICGKGFSVSSSLAVHQRVHTGEKPYKCDTCGKAFNQTAKLGLHQKIHTGEKSYKCDVCGKAFSRTGNLTVHRRVHTGEKPYKCDMCGKAFRVSSNLAVHQRVHTGEKPYKCDVCGKAFSQATGLAVHQRIHTGEKPYKCDVCGKAFNHTTRLQLHQRIHTGEKPYKCNVCDKAFISAANLSVHRKLHTGEKPYKCDICGKGFRVSSNLGIHRSVHTGEKPYKCDVCGKAFSHTGNLAVHRRVHTGEKPYKCDVCGKAFSCTGNLAVHRRLHTGEKPYKCDVCGKAFSRTGNLAVHRRLHTGK", "length": 924, "header": "tr|A0ABI0NNH4-1|A0ABI0NNH4_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC112442366 PE=3 SV=1 CANONICAL=A0ABI0NIZ1-1" }, "locus": { "chromosome": "18", "start_pos": 59820297, "end_pos": 59814305, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152190.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152190.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106924.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106924.1" } ] } }, { "isoform_ac": "A0ABI0NPR3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1/entry#A0ABI0NPR3-1", "sequence": { "sequence": "MDEGAQKRKEQESGMALSQAQLTFKDVFIDFTPEEWECLDPAQRTLYKDVMVETLGNLLSVDMSQIDMIKKLQAKADSGKGEIFQRVMFERAESLESKDFHLRKMQENIDDFDCLRTDDERNDKGLSTSHNKNLTDGRDHHSRSDAENGTFERHGSSFQDESQMMQSEGIIFECSQVVTDVSASGLSSQRTLNVCKGFSHKDENAVMHPSELLPDHETQNKRPYKCNECDITFLQDSELTRHQRIHTGGKPYKCDVCGKAFNQTRKLAIHWRIHTGEKPHKCDVCGKVFKQAAKFLIHWRYHMREKPYKCDVCGKAFSQTANLAVHQRIHTGEKPYKCNVCGKAFNHSANLAVHQRVHTGEKPYKCDVCGKAFNQTAKLGLHQKIHTGEKSYKCDVCGKAFSRTGNLAVHRRVHTGEKPYKCDICGKAFRVTSHLADHRRVHTGEKPYKCNVCDKAFSRAANLTVHWRIHTGEKPYKCDVCGKAFNHTTRLQLHQRIHTGEKPYKCNVCERAFSHTSSLSVHRRLHTGVKPYKCDICGRAFSQTASLALHRSIHTGEKPYKCDVCGKAFNQTAKLRLHRRIHTGEKPYKCCVCGKAFSHTTGLELHQRIHTGEKPYKCNVCDKAFSHSSNLTVHRRLHAGEKPYKCDICGKGFSVSSSLAVHQRVHTGEKPYKCDTCGKAFNQTAKLGLHQKIHTGEKSYKCDVCGKAFSRTGNLTVHRRVHTGEKPYKCDMCGKAFRVSSNLAVHQRVHTGEKPYKCDVCGKAFSQATGLAVHQRIHTGEKPYKCDVCGKAFNHTTRLQLHQRIHTGEKPYKCNVCDKAFISAANLSVHRKLHTGEKPYKCDICGKGFRVSSNLGIHRSVHTGEKPYKCDVCGKAFSHTGNLAVHRRVHTGEKPYKCDVCGKAFSCTGNLAVHRRLHTGEKPYKCDVCGKAFSRTGNLAVHRRLHTGK", "length": 949, "header": "tr|A0ABI0NPR3-1|A0ABI0NPR3_BOVIN Computationally mapped isoform of Zinc finger protein 665-like OS=Bos taurus OX=9913 GN=LOC112442366 PE=3 SV=1 CANONICAL=A0ABI0NIZ1-1" }, "locus": { "chromosome": "18", "start_pos": 59826660, "end_pos": 59814305, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138539.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138539.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105089.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105089.1" } ] } }, { "isoform_ac": "A0ABI0P6K8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1/entry#A0ABI0P6K8-1", "sequence": { "sequence": "MVETLGNLLSVDMSQIDMIKKLQAKADSGKGEIFQRVMFERAESLESKDFHLRKMQENIDDFDCLRTDDERNDKGLSTSHNKNLTDGRDHHSRSDAENGTFERHGSSFQDESQMMQSEGIIFECSQVVTDVSASGLSSQRTLNVCKGFSHKDENAVMHPSELLPDHETQNKRPYKCNECDITFLQDSELTRHQRIHTGGKPYKCDVCGKAFNQTRKLAIHWRIHTGEKPHKCDVCGKVFKQAAKFLIHWRYHMREKPYKCDVCGKAFSQTANLAVHQRIHTGEKPYKCNVCGKAFNHSANLAVHQRVHTGEKPYKCDVCGKAFNQTAKLGLHQKIHTGEKSYKCDVCGKAFSRTGNLAVHRRVHTGEKPYKCDICGKAFRVTSHLADHRRVHTGEKPYKCNVCDKAFSRAANLTVHWRIHTGEKPYKCDVCGKAFNHTTRLQLHQRIHTGEKPYKCNVCERAFSHTSSLSVHRRLHTGVKPYKCDICGRAFSQTASLALHRSIHTGEKPYKCDVCGKAFNQTAKLRLHRRIHTGEKPYKCCVCGKAFSHTTGLELHQRIHTGEKPYKCNVCDKAFSHSSNLTVHRRLHAGEKPYKCDICGKGFSVSSSLAVHQRVHTGEKPYKCDTCGKAFNQTAKLGLHQKIHTGEKSYKCDVCGKAFSRTGNLTVHRRVHTGEKPYKCDMCGKAFRVSSNLAVHQRVHTGEKPYKCDVCGKAFSQATGLAVHQRIHTGEKPYKCDVCGKAFNHTTRLQLHQRIHTGEKPYKCNVCDKAFISAANLSVHRKLHTGEKPYKCDICGKGFRVSSNLGIHRSVHTGEKPYKCDVCGKAFSHTGNLAVHRRVHTGEKPYKCDVCGKAFSCTGNLAVHRRLHTGEKPYKCDVCGKAFSRTGNLAVHRRLHTGK", "length": 899, "header": "tr|A0ABI0P6K8-1|A0ABI0P6K8_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC112442366 PE=3 SV=1 CANONICAL=A0ABI0NIZ1-1" }, "locus": { "chromosome": "18", "start_pos": 59822116, "end_pos": 59814305, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138030.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138030.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107607.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107607.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" }, { "start_pos": 716, "end_pos": 718, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 828, "end_pos": 830, "annotation": "n_glycosylation_sequon" }, { "start_pos": 860, "end_pos": 862, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NIZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIZ1" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 258, "end_pos": 285, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 408, "end_pos": 410 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 520, "end_pos": 522 }, { "start_pos": 604, "end_pos": 606 }, { "start_pos": 664, "end_pos": 666 }, { "start_pos": 716, "end_pos": 718 }, { "start_pos": 748, "end_pos": 750 }, { "start_pos": 828, "end_pos": 830 }, { "start_pos": 860, "end_pos": 862 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NLS9-1", "uniprot_ac": "A0ABI0NLS9", "uniprot_id": "A0ABI0NLS9_BOVIN", "mass": { "chemical_mass": 76498.0, "monoisotopic_mass": 76498.0 }, "refseq": {}, "gene_names": [ { "name": "CSF2RA", "type": "recommended", "evidence": [ { "id": "A0ABI0NLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9" } ] } ], "protein_names": [ { "name": "Fibronectin type-III domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLS9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CSF2RA", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9", "locus": { "chromosome": "3", "start_pos": 119452615, "end_pos": 119422629, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045948", "url": "https://www.ensembl.org/id/ENSBTAG00000045948" } ] } } ], "crossref": [ { "id": "100336606", "url": "https://www.ncbi.nlm.nih.gov/gene/100336606", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TA40", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TA40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TA40-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TA40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLS6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLS6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLS9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLS9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P007", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P007", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P007-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P007-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLVGWGALCYPLCVSTPHHHPEAGTTVCPVEEKAGLRELALLRCLGSPGSLLATVVLLSMVLDSAWLLTQEQQDLPTVKPNASLNVKFDPQTTKLTWDCRENASSGECVLIHKEKGPIKKKVKDSECQCTFQDYSLHGGVTLTVEVHVNQRRLSEMLVYTNPGREGTAAQNFSCVIYDADFMNCSWAKGRAAPDDVQYFLYIRSKKRIERECPRYLKDSGTHVGCHLQDLSGLTSYNYFLVNGTSQETGIQFFDSVLLLKEIEQYNPPDNITVQCNESHCLIRWEKPRTRQPWPNREFQYQLDIQRRRDTSSGRSQLIVVFGDSGNRYNFPKPGSKAKHTVKIRTADARKAHWGAWSQPVEFGSEETGSSLVHIYVLVVLGTLVCGLTLGCLFKRFLKSHRLFPPVPQIKDKLNDNHQVDHEVQLQICSMVVLLDFVILLVLLNSARSTVLAGEKESPIVNLTLDSRKKILSWNSRRIVTQQTCAIVTPLDPDTSQEPQVRNDTYFCTFPNAVLHRGATLTVNATSEGQDFSHQLAFSNPGKEGSGAQDLSCIIYNVRLMNCSWTRGPAAPADVQYQLYSWTSLHGNVSECSHYVLDSAGTRVGCHFDELGEGHTTDDYFFLVNGTSSDSDIQFLDSPSVNGPSLGKTVNRSPCIRLLLCQPSASWHLHLSQGSGGCVFPQQDLH", "length": 686, "header": "tr|A0ABI0NLS9-1|A0ABI0NLS9_BOVIN Isoform 1 of Fibronectin type-III domain-containing protein OS=Bos taurus OX=9913 GN=CSF2RA PE=4 SV=1 CANONICAL=A0ABI0NLS9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TA40-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9/entry#A0AAA9TA40-1", "sequence": { "sequence": "MGNAALLRCLGSPGSLLATVVLLSMVLDSAWLLTQEQQDLPTVKPNASLNVKFDPQTTKLTWDCRENASSGECVLIHKEKGPIKKKVKDSECQCTFQDYSLHGGVTLTVEVHVNQRRLSEMLVYTNPGREGTAAQNFSCVIYDADFMNCSWAKGRAAPDDVQYFLYIRSKKRIERECPRYLKDSGTHVGCHLQDLSGLTSYNYFLVNGTSQETGIQFFDSVLLLKEIEQYNPPDNITVQCNESHCLIRWEKPRTRQPWPNREFQYQLDIQRRRDTSSGRSQLIVVFGDSGNRYNFPKPGSKAKHTVKIRTADARKAHWGAWSQPVEFGSEETGSSLVHIYVLVVLGTLVCGLTLGCLFKRFLKSHRLFPPVPQIKDKLNDNHQVDHEERRNLLL", "length": 394, "header": "tr|A0AAA9TA40-1|A0ABI0NLS9_BOVIN Computationally mapped isoform of Fibronectin type-III domain-containing protein OS=Bos taurus OX=9913 GN=CSF2RA PE=4 SV=2 CANONICAL=A0ABI0NLS9-1" }, "locus": { "chromosome": "Y", "start_pos": 691582, "end_pos": 653975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135773.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135773.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093746.2", "url": "https://www.ensembl.org/id/ENSBTAP00000093746.2" } ] } }, { "isoform_ac": "A0AAA9TPJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9/entry#A0AAA9TPJ2-1", "sequence": { "sequence": "MGNAALLRCLGSPGSLLATVVLLSMVLDSAWLLTQEQQDLPTVKPNASLNVKFDPQTTKLTWDCRENASSGECVLIHKEKGPIKKKVKDSECQCTFQDYSLHGGVTLTVEVHVNQRRLSEMLVYTNPGREGTAAQNFSCVIYDADFMNCSWAKGRAAPDDVQYFLYIRSKKRIERECPRYLKDSGTHVGCHLQDLSGLTSYNYFLVNGTSQETGIQFFDSVLLLKEIEQYNPPDNITVQCNESHCLIRWEKPRTRQPWPNREFQYQLDIQRRRDTSSGRSQLIVVFGDSGNRYNFPKPGSKAKHTVKIRTADARKAHWGAWSQPVEFGSEETGSSLVHIYVLVVLGTLVCGLTLGCLFKRFLKSHRLFPPVPQIKDKLNDNHQVDHEETQEREDHPEERMATHSRVLT", "length": 408, "header": "tr|A0AAA9TPJ2-1|A0ABI0NLS9_BOVIN Computationally mapped isoform of Fibronectin type-III domain-containing protein OS=Bos taurus OX=9913 GN=CSF2RA PE=4 SV=2 CANONICAL=A0ABI0NLS9-1" }, "locus": { "chromosome": "Y", "start_pos": 681711, "end_pos": 653975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135821.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135821.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098284.2", "url": "https://www.ensembl.org/id/ENSBTAP00000098284.2" } ] } }, { "isoform_ac": "A0ABI0NLS6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9/entry#A0ABI0NLS6-1", "sequence": { "sequence": "MGGGVEARGPAYPSSSSWQAWQGEGIEEKKTGTQLTASGRAVHGPSLSGEKERRRGGQTWKPGRRAMGNAALLRCLGSPGSLLATVVLLSMVLDSAWLLTQEQQDLPTVKPNASLNVKFDPQTTKLTWDCRENASSGECVLIHKEKGPIKKKVKDSECQCTFQDYSLHGGVTLTVEVHVNQRRLSEMLVYTNPGREGTAAQNFSCVIYDADFMNCSWAKGRAAPDDVQYFLYIRSKKRIERECPRYLKDSGTHVGCHLQDLSGLTSYNYFLVNGTSQETGIQFFDSVLLLKEIEQYNPPDNITVQCNESHCLIRWEKPRTRQPWPNREFQYQLDIQRRRDTSSGRSQLIVVFGDSGNRYNFPKPGSKAKHTVKIRTADARKAHWGAWSQPVEFGSEETGSSLVHIYVLVVLGTLVCGLTLGCLFKRFLKSHRLFPPVPQIKDKLNDNHQVDHEMLWEKFTHETGKSDKEEVLTVETVSEAPAKL", "length": 484, "header": "tr|A0ABI0NLS6-1|A0ABI0NLS6_BOVIN Computationally mapped isoform of Fibronectin type-III domain-containing protein OS=Bos taurus OX=9913 GN=CSF2RA PE=4 SV=1 CANONICAL=A0ABI0NLS9-1" }, "locus": { "chromosome": "Y", "start_pos": 676180, "end_pos": 653777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151825.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151825.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106149.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106149.1" } ] } }, { "isoform_ac": "A0ABI0NLS9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9/entry#A0ABI0NLS9-1", "sequence": { "sequence": "MSLVGWGALCYPLCVSTPHHHPEAGTTVCPVEEKAGLRELALLRCLGSPGSLLATVVLLSMVLDSAWLLTQEQQDLPTVKPNASLNVKFDPQTTKLTWDCRENASSGECVLIHKEKGPIKKKVKDSECQCTFQDYSLHGGVTLTVEVHVNQRRLSEMLVYTNPGREGTAAQNFSCVIYDADFMNCSWAKGRAAPDDVQYFLYIRSKKRIERECPRYLKDSGTHVGCHLQDLSGLTSYNYFLVNGTSQETGIQFFDSVLLLKEIEQYNPPDNITVQCNESHCLIRWEKPRTRQPWPNREFQYQLDIQRRRDTSSGRSQLIVVFGDSGNRYNFPKPGSKAKHTVKIRTADARKAHWGAWSQPVEFGSEETGSSLVHIYVLVVLGTLVCGLTLGCLFKRFLKSHRLFPPVPQIKDKLNDNHQVDHEVQLQICSMVVLLDFVILLVLLNSARSTVLAGEKESPIVNLTLDSRKKILSWNSRRIVTQQTCAIVTPLDPDTSQEPQVRNDTYFCTFPNAVLHRGATLTVNATSEGQDFSHQLAFSNPGKEGSGAQDLSCIIYNVRLMNCSWTRGPAAPADVQYQLYSWTSLHGNVSECSHYVLDSAGTRVGCHFDELGEGHTTDDYFFLVNGTSSDSDIQFLDSPSVNGPSLGKTVNRSPCIRLLLCQPSASWHLHLSQGSGGCVFPQQDLH", "length": 686, "header": "tr|A0ABI0NLS9-1|A0ABI0NLS9_BOVIN Isoform 1 of Fibronectin type-III domain-containing protein OS=Bos taurus OX=9913 GN=CSF2RA PE=4 SV=1 CANONICAL=A0ABI0NLS9-1" }, "locus": { "chromosome": "Y", "start_pos": 695504, "end_pos": 656218, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149892.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149892.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105829.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105829.1" } ] } }, { "isoform_ac": "A0ABI0P007-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9/entry#A0ABI0P007-1", "sequence": { "sequence": "MVLDSAWLLTQEQQDLPTVKPNASLNVKFDPQTTKLTWDCRENASSGECVLIHKEKGPIKKKVKDSECQCTFQDYSLHGGVTLTVEVHVNQRRLSEMLVYTNPGREGTAAQNFSCVIYDADFMNCSWAKGRAAPDDVQYFLYIRSKKRIERECPRYLKDSGTHVGCHLQDLSGLTSYNYFLVNGTSQETGIQFFDSVLLLKEIEQYNPPDNITVQCNESHCLIRWEKPRTRQPWPNREFQYQLDIQRRRDTSSGRSQLIVVFGDSGNRYNFPKPGSKAKHTVKIRTADARKAHWGAWSQPVEFGSEETGSSLVHIYVLVVLGTLVCGLTLGCLFKRFLKSHRLFPPVPQIKDKLNDNHQVDHEMLWEKFTHETGKSDKEEVLTVETVSEAPAKL", "length": 394, "header": "tr|A0ABI0P007-1|A0ABI0P007_BOVIN Computationally mapped isoform of Fibronectin type-III domain-containing protein OS=Bos taurus OX=9913 GN=CSF2RA PE=4 SV=1 CANONICAL=A0ABI0NLS9-1" }, "locus": { "chromosome": "Y", "start_pos": 676180, "end_pos": 660306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147438.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147438.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104501.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104501.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLS9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLS9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLS9" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 268, "end_pos": 368, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137343" } ] }, { "name": "chloride channel 1, skeletal muscle C-type", "type": "synonym", "evidence": [ { "id": "NP_001137343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137343" } ] }, { "name": "chloride channel protein 1", "type": "synonym", "evidence": [ { "id": "NP_001137343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137343" } ] } ], "function": [ { "annotation": "Voltage-gated chloride channel involved in skeletal muscle excitability. Generates most of the plasma membrane chloride conductance in skeletal muscle fibers, stabilizes the resting membrane potential and contributes to the repolarization phase during action potential firing. Forms a homodimeric channel where each subunit has its own ion conduction pathway. Conducts double-barreled currents controlled by two types of gates, two fast glutamate gates that control each subunit independently and a slow common gate that opens and shuts off both subunits simultaneously. Has a significant open probability at muscle resting potential and is further activated upon membrane depolarization. Permeable to small monovalent anions with ion selectivity for chloride > thiocyanate > bromide > nitrate > iodide.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TLE4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLE4#function" }, { "database": "UniProtKB", "id": "ARBA00057972", "url": "https://www.uniprot.org/uniprotkb/ARBA00057972#function" }, { "database": "UniProtKB", "id": "E1BLQ0", "url": "https://www.uniprot.org/uniprotkb/E1BLQ0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLQ0", "url": "https://www.uniprot.org/uniprotkb/E1BLQ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CLCN1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ0", "locus": { "chromosome": "4", "start_pos": 106737587, "end_pos": 106700961, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009182", "url": "https://www.ensembl.org/id/ENSBTAG00000009182" } ] } } ], "crossref": [ { "id": "E1BLQ0", "url": "https://alphafold.ebi.ac.uk/entry/E1BLQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009182", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009182", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04591", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04591", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514597", "url": "https://www.ncbi.nlm.nih.gov/gene/514597", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001807", "database": "InterPro", "categories": [ "Protein 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45720:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45720:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001137343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137343", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34923", "url": "https://www.rhea-db.org/rhea/34923", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "66324", "url": "https://www.rhea-db.org/rhea/66324", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "75347", "url": "https://www.rhea-db.org/rhea/75347", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "75383", "url": "https://www.rhea-db.org/rhea/75383", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TLE4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLE4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLQ0", "url": "https://www.uniprot.org/uniprotkb/E1BLQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLQ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 988, "header": "tr|E1BLQ0-1|E1BLQ0_BOVIN Isoform 1 of Chloride channel protein 1 OS=Bos taurus OX=9913 GN=CLCN1 PE=3 SV=3 CANONICAL=E1BLQ0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TLE4-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ0/entry#A0AAA9TLE4-1", "sequence": { "sequence": 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"length": 988, "header": "tr|A0AAA9TLE4-1|E1BLQ0_BOVIN Computationally mapped isoform of Chloride channel protein 1 OS=Bos taurus OX=9913 GN=CLCN1 PE=3 SV=1 CANONICAL=E1BLQ0-1" }, "locus": { "chromosome": "4", "start_pos": 106737427, "end_pos": 106700961, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109984.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109984.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097115.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097115.1" } ] } }, { "isoform_ac": "E1BLQ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ0/entry#E1BLQ0-1", "sequence": { "sequence": "MEPSGAQQRGGEPSWWGSAPQYQYMPFEHCTSYGLPSEDGGLQRRLRRDAGPRASAHPTQIYGHHKGQFSGKEQDNEMPKTMGSSASMDSKDEDHYSKCQDCMHRLGLVVRRKLGEDWIFLVLLGLLMALVSWCMDYVSAKTLQAYKWSYYQMQPSLPLQFLVWVGFPLILILFSALFCQIISPQAVGSGIPEMKTILRGVVLKEYLTLKAFVAKVVALTAGLGSGIPVGKEGPFVHIASICAAILSKFMSVFCGVYEQPYYYTDMLTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLQELPAFAIIGICCGFLGAVFVYLHRQVMLGVRKHKVLSQFLAKHRLLYPGIVTFVIASFTFPPGIGQFMAGELMPREAISTLFDNNTWVKHIGDPESLGRSAVWIHPKASVVIVLLLFFIMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKFTIFVEDIMVRDVKFVSASCTYGELRNLLQTTTVKTLPLVESKDSMILLGSVERSELQSLLQRHLCPERRLRLAQEMARKLSELPFDGKVRPARGRSGVWPQGRPESFAFVDEDADEDLYGKPEMPPLHPSHPLPTDPLPPEEPNGPLPSHKQQLEALESTGPRPSIFQSLLRCLLGRARPKKKKMTQDSTDLVDNMSPEEIEAWEQEQLGQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRSTTSTRKNTGVPLPPAEGWSLPEDGAGATGAGDVTPASPETPVPSPFPERPLSGAPAKAESELEELELVEGPGPEEELADILQGPSLRSTDEEDGDELIL", "length": 988, "header": "tr|E1BLQ0-1|E1BLQ0_BOVIN Isoform 1 of Chloride channel protein 1 OS=Bos taurus OX=9913 GN=CLCN1 PE=3 SV=3 CANONICAL=E1BLQ0-1" }, "locus": { "chromosome": "4", "start_pos": 106737427, "end_pos": 106700961, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012099.7", "url": "https://www.ensembl.org/id/ENSBTAT00000012099.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012099.7", "url": "https://www.ensembl.org/id/ENSBTAP00000012099.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514597", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514597", "resource": "KEGG Pathway" }, { "id": "R-BTA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular 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"url": "https://www.uniprot.org/uniprotkb/E1BLQ0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ0", "url": "https://www.uniprot.org/uniprotkb/E1BLQ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "muscle contraction", "id": "GO:0006936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006936", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ0", "url": "https://www.uniprot.org/uniprotkb/E1BLQ0" } ], "pmid": "" }, { "name": "chloride transport", "id": "GO:0006821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006821", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ0", "url": "https://www.uniprot.org/uniprotkb/E1BLQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 796, "end_pos": 798, 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"MNEADRLLLRRYRVRLVGELQVASLWDALLSRELFTPDMIEDIQRAGSGSRRDQARQLILDLETRGSQALPLFISCLEDTGQDTLASLLKTSRQAAKQDDPSKPSQGKLAPVVLGPEELWPAKLRPEVLRPEVPRAVDAGSGGFTDVCPQDRAKGNADLAYVLNADPCGHCLIINNVNFCRESGLRARTGSNIDCERMRRRFHLLQFVVEVKCDLTAKQMVQALMQLARQDHSALDCCMVVILSHGCQASHLQFPGAVYGTDGCPVSVERIVNTFNGTGCPSLRGKPKLFFIQACGGEQKDHGFEVESTSPEDKTPSSDPEADATPFQEGPRSIDEPDAVSSLPTPSDILVSYSTFPGFVSWRDPKSGSWYIETLDSIFEQWAHCEDLQTLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKT", "length": 423, "header": "tr|E1BNU2-1|E1BNU2_BOVIN Isoform 1 of Caspase-9 OS=Bos taurus OX=9913 GN=CASP9 PE=3 SV=3 CANONICAL=E1BNU2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TVV3-1", "url": "https://www.uniprot.org/uniprotkb/E1BNU2/entry#A0AAA9TVV3-1", "sequence": { "sequence": "MNEADRLLLRRYRVRLVGELQVASLWDALLSRELFTPDMIEDIQRAGSGSRRDQARQLILDLETRGSQALPLFISCLEDTGQDTLASLLKTSRQAAKQDVEAIRPLDLKPVVLGPEGLKPGEPRVMKQDPSKPSQGKLAPVVLGPEELWPAKLRPEVLRPEVPRAVDAGSGGFTDVCPQDRAKGNADLAYVLNADPCGHCLIINNVNFCRESGLRARTGSNIDCERMRRRFHLLQFVVEVKCDLTAKQMVQALMQLARQDHSALDCCMVVILSHGCQASHLQFPGAVYGTDGCPVSVERIVNTFNGTGCPSLRGKPKLFFIQACGGEQKDHGFEVESTSPEDKTPSSDPEADATPFQEGPRSIDEPDAVSSLPTPSDILVSYSTFPGERIRRPRPSSWQVRSSALEAAVL", "length": 410, "header": "tr|A0AAA9TVV3-1|E1BNU2_BOVIN Computationally mapped isoform of Caspase-9 OS=Bos taurus OX=9913 GN=CASP9 PE=3 SV=2 CANONICAL=E1BNU2-1" }, "locus": { "chromosome": "16", "start_pos": 52018737, "end_pos": 52000725, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099029.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099029.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101295.2", "url": "https://www.ensembl.org/id/ENSBTAP00000101295.2" } ] } }, { "isoform_ac": "E1BNU2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNU2/entry#E1BNU2-1", "sequence": { "sequence": "MNEADRLLLRRYRVRLVGELQVASLWDALLSRELFTPDMIEDIQRAGSGSRRDQARQLILDLETRGSQALPLFISCLEDTGQDTLASLLKTSRQAAKQDDPSKPSQGKLAPVVLGPEELWPAKLRPEVLRPEVPRAVDAGSGGFTDVCPQDRAKGNADLAYVLNADPCGHCLIINNVNFCRESGLRARTGSNIDCERMRRRFHLLQFVVEVKCDLTAKQMVQALMQLARQDHSALDCCMVVILSHGCQASHLQFPGAVYGTDGCPVSVERIVNTFNGTGCPSLRGKPKLFFIQACGGEQKDHGFEVESTSPEDKTPSSDPEADATPFQEGPRSIDEPDAVSSLPTPSDILVSYSTFPGFVSWRDPKSGSWYIETLDSIFEQWAHCEDLQTLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKT", "length": 423, "header": "tr|E1BNU2-1|E1BNU2_BOVIN Isoform 1 of Caspase-9 OS=Bos taurus OX=9913 GN=CASP9 PE=3 SV=3 CANONICAL=E1BNU2-1" }, "locus": { "chromosome": "16", "start_pos": 52021399, "end_pos": 52000725, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003205.8", "url": "https://www.ensembl.org/id/ENSBTAT00000003205.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003205.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003205.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 345, "start_aa": "Thr", "end_pos": 345, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr345", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Endothelial cell apoptosis induced by bacteria-activated platelets requires caspase-8 and -9 and generation of reactive oxygen species.", "journal": "Thrombosis and haemostasis", "date": "2008-02", "authors": "Kuckleburg Christopher J, Tiwari Raksha, Czuprynski Charles J", "evidence": [ { "database": "RefSeq", "id": "NP_001192433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192433" } ], "reference": [ { "type": "PubMed", "id": "18278187", "url": "https://glygen.org/publication/PubMed/18278187" } ] }, { "title": "Role of caspase-9 in the effector caspases and genome expressions, and growth of bovine skeletal myoblasts.", "journal": "Development, growth & differentiation", "date": "2014-02", "authors": "Van Ba Hoa, Hwang Inho", "evidence": [ { "database": "RefSeq", "id": "NP_001192433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192433" } ], "reference": [ { "type": "PubMed", "id": "24289185", "url": "https://glygen.org/publication/PubMed/24289185" } ] } ], "pathway": [ { "id": "bta:100140945", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140945", "resource": "KEGG Pathway" }, { "id": "R-BTA-111458", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111458", "resource": "Reactome", "description": "Formation of apoptosome" }, { "id": "R-BTA-111459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111459", "resource": "Reactome", "description": "Activation of caspases through apoptosome-mediated cleavage" }, { "id": "R-BTA-418889", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418889", "resource": "Reactome", "description": "Caspase activation via Dependence Receptors in the absence of ligand" }, { "id": "R-BTA-9627069", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9627069", "resource": "Reactome", "description": "Regulation of the apoptosome activity" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QSB1-1", "protein_name": "Caspase-9", "gene_name": "casp9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEQKHRQILQRHRLNLVKALNPEDVCDKLLSKGVFTQDMIDEIQSKATRRDQARQLVKDLETRGSLAFPAFLDSLRETGHNDLAELLQSGDGVHRPPVISVQPSPIPLPVQNLNHTEKPDKPDIASPRLVPLRPESLPVHKTYSPPSETVVRPTRPRRDSIQCYKMDASPCGVCLIINNINFEKASELNDRKGSNIDCDKLEKRFKALNFEVTVKRNLKSKRIRHEMASLAKKDHSTYDCCVVIILSHGTEASHNRFPGAVHGVDGPAVPIQIITNYLNGQNCPSLQGKPKLFFIQACGGGEKDIGFEVSPDDVQPSIGGIDDEMDAIPMSSSSDSLSTASDELDARASLPTPSDILVSYSTFPGYVSWRDTEAGSWYVENLDRVLEENAITDDLVTMLMLVNDAVSQISAKGLYKQMPGSFNFLRKLLYFQSSQS", "length": 436 }, "evidence": [ { "id": "E1BNU2", "url": "https://omabrowser.org/oma/group/E1BNU2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9JHK1-1", "protein_name": "Caspase-9", "gene_name": "Casp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEADRQLLRRCRVRLVRELQVAELWDALLSRELFTRDMIEDIQRAGSGSRRDQARQLVIDLETRGRQALPRFISCLEDTGQGSLASFLQSSGQAAKQDPEAVTPLDHLVPVVLGPMGLKSKEQKVVKLDPSQPALGNLTPVVLGPEELWPTRLRPEVLTPETPRPVDIGSGRAHDVCTPGKIERHADMAYTLDSDPCGHCLIINNVNFCPSSGLSTRIGSHVDCEKLQHRFCWLRFMVEVKNDLTAKKMVTALMEMAHRDHRALDCFVVVILSHGCQASHLQFPGAVYGTDGCSVSIERIVNIFNGTGCPSLGGKPKLFFIQACGGEQKDHGFEVAFTSSQDKAFDSDSEPDAVPYQEGPRTLDQLDAVSSLPTPSDILVSYSTFPGFVSWRDKKSGSWYIETLDGVLEQWARSEDLQSLLLRVANAVSEKGVYKQIPGCFNFLRKKLFFKTS", "length": 454 }, "evidence": [ { "id": "E1BNU2", "url": "https://omabrowser.org/oma/group/E1BNU2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "signal transduction in response to DNA damage", "id": "GO:0042770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042770", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "cellular response to dexamethasone stimulus", "id": "GO:0071549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071549", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "positive regulation of neuron apoptotic process", "id": "GO:0043525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043525", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "cellular response to UV", "id": "GO:0034644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034644", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "positive regulation of execution phase of apoptosis", "id": "GO:1900119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900119", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" }, { "name": "apoptosome", "id": "GO:0043293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043293", "evidence": [ { "database": "UniProtKB", "id": "E1BNU2", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-114252", "name": "Cleavage of Procaspase-3 by the apoptosome", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "F1MB04-1", "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-114252", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114252" } ] }, { "id": "R-BTA-114256", "name": "CYCS:APAF1 binds procaspase-9", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VCJ2-1", "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-114256", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114256" } ] }, { "id": "R-BTA-114259", "name": "Cleavage of Procaspase9 to caspase9", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-114259", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114259" } ] }, { "id": "R-BTA-114261", "name": "Cleavage of Procaspase-7 by the apoptosome", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S706-1", "A0ABI0NI58-1", "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-114261", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114261" } ] }, { "id": "R-BTA-373700", "name": "Caspase-9 binds DCC:DIP13alpha complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-373700", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-373700" } ] }, { "id": "R-BTA-418845", "name": "Activation of caspase-3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MB04-1", "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-418845", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418845" } ] }, { "id": "R-BTA-6804596", "name": "APAF1:CYCS binds APIP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VCJ2-1", "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-6804596", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804596" } ] }, { "id": "R-BTA-9627056", "name": "Procaspase 9 forms dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-9627056", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9627056" } ] }, { "id": "R-BTA-9627078", "name": "XIAP binds CASP9", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-9627078", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9627078" } ] }, { "id": "R-BTA-9627089", "name": "CASP9 is phosphorylated at T412", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P46196-1", "E1B8P9-1", "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-9627089", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9627089" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9S706", "gene_name": "CASP7", "activity": [ { "ec_number": "3.4.22.56", "activity": "Strict requirement for an Asp residue at positions P1 and P4. It has a preferred cleavage sequence of Asp-Xaa-Xaa-Asp-|- with a hydrophobic amino-acid residue at P2 and a hydrophilic amino-acid residue at P3, although Val or Ala are also accepted at this position.", "evidence": [ { "id": "A0AAA9S706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S706" } ] }, { "ec_number": "3.4.22.56", "activity": "", "evidence": [ { "id": "A0AAA9S706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S706" } ] } ] }, { "uniprot_ac": "A0ABI0NI58", "gene_name": "XIAP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0ABI0NI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0ABI0NI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1BNU2", "gene_name": "CASP9", "activity": [ { "ec_number": "3.4.22.62", "activity": "Strict requirement for an Asp residue at position P1 and with a marked preference for His at position P2. It has a preferred cleavage sequence of Leu-Gly-His-Asp-|-Xaa.", "evidence": [ { "id": "E1BNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ] }, { "ec_number": "3.4.22.62", "activity": "", "evidence": [ { "id": "E1BNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ] } ] }, { "uniprot_ac": "F1MB04", "gene_name": "CASP3", "activity": [ { "ec_number": "3.4.22.56", "activity": "Strict requirement for an Asp residue at positions P1 and P4. It has a preferred cleavage sequence of Asp-Xaa-Xaa-Asp-|- with a hydrophobic amino-acid residue at P2 and a hydrophilic amino-acid residue at P3, although Val or Ala are also accepted at this position.", "evidence": [ { "id": "F1MB04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB04" } ] }, { "ec_number": "3.4.22.56", "activity": "", "evidence": [ { "id": "F1MB04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB04" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "Q0VCJ2", "gene_name": "APIP", "activity": [ { "ec_number": "4.2.1.109", "activity": "5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O.", "evidence": [ { "id": "Q0VCJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCJ2" } ] }, { "ec_number": "4.2.1.109", "activity": "", "evidence": [ { "id": "Q0VCJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCJ2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" }, { "id": "PS50209", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50209" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CARD", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 92, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" }, { "id": "PS50207", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50207" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Caspase family p10", "eco_id": "ECO_0000259", "start_pos": 339, "end_pos": 403, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" }, { "id": "PS50208", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50208" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Caspase family p20", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 299, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.22.62", "ec_name": "Strict requirement for an Asp residue at position P1 and with a marked preference for His at position P2. It has a preferred cleavage sequence of Leu-Gly-His-Asp-|-Xaa.", "evidence": [ { "id": "3.4.22.62", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.22.62" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 345 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 276, "end_pos": 278 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0ABI0NL01-1", "uniprot_ac": "A0ABI0NL01", "uniprot_id": "A0ABI0NL01_BOVIN", "mass": { "chemical_mass": 53540.0, "monoisotopic_mass": 53540.0 }, "refseq": { "ac": "XP_059746503", "name": "nuclear receptor ROR-alpha isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059746503" }, "gene_names": [ { "name": "RORA", "type": "recommended", "evidence": [ { "id": "A0ABI0NL01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL01" } ] }, { "name": "RORA", "type": "synonym", "evidence": [ { "id": "XP_059746503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059746503" } ] } ], "protein_names": [ { "name": "RAR related orphan receptor A", "type": "synonym", "evidence": [ { "id": "A0ABI0NL01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL01/entry#names_and_taxonomy" } ] }, { "name": "nuclear receptor ROR-alpha isoform X3", "type": "synonym", "evidence": [ { "id": "XP_059746503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059746503" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL01", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL01" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RORA", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL01", "locus": { "chromosome": "10", "start_pos": 49703164, "end_pos": 49591179, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015904", "url": "https://www.ensembl.org/id/ENSBTAG00000015904" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015904", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015904", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06968", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06968", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "535597", "url": "https://www.ncbi.nlm.nih.gov/gene/535597", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:535597", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535597", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N7R0", "url": "https://www.orthodb.org/?gene=F1N7R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45805", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45805", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45805:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45805:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4090294", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4090294", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_059746503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059746503", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF46", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF46-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL01", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL01-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSI5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSI5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P178", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P178", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P178-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P178-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7R0", "url": "https://www.uniprot.org/uniprotkb/F1N7R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7R0-1", "url": "https://www.uniprot.org/uniprotkb/F1N7R0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "length": 468, "header": "tr|A0ABI0NL01-1|A0ABI0NL01_BOVIN Isoform 1 of RAR related orphan receptor A OS=Bos taurus OX=9913 GN=RORA PE=3 SV=1 CANONICAL=A0ABI0NL01-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MF46-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL01/entry#A0A3Q1MF46-1", "sequence": { "sequence": "MESAPAAPDPAASEPGSSGSDAAAGSRETPLNQESARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "length": 523, "header": "tr|A0A3Q1MF46-1|A0ABI0NL01_BOVIN Computationally mapped isoform of RAR related orphan receptor A OS=Bos taurus OX=9913 GN=RORA PE=3 SV=2 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468, "header": "tr|A0ABI0NL01-1|A0ABI0NL01_BOVIN Isoform 1 of RAR related orphan receptor A OS=Bos taurus OX=9913 GN=RORA PE=3 SV=1 CANONICAL=A0ABI0NL01-1" }, "locus": { "chromosome": "10", "start_pos": 49692315, "end_pos": 49591322, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148533.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148533.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105598.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105598.1" } ] } }, { "isoform_ac": "A0ABI0NSI5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL01/entry#A0ABI0NSI5-1", "sequence": { "sequence": 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}, { "id": "NP_001192521", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192521", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NI58-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWG5", "url": "https://www.uniprot.org/uniprotkb/G3MWG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWG5-1", "url": "https://www.uniprot.org/uniprotkb/G3MWG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTFNSFEGSKTCVPADIDKDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAIGRHRRVSPNCRFINGFYFENNAAQPTYSGVQNGQYKAENYLGNRNHFVLERPSETHAHYLLRTGQVVDLSDTVYPRNPVMCSEEARLKSFHNWPDYAHLTPRELARAGLYYTGIDDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNINMQSESSVVSSDRNFPNSTNAPINPAMADYEARIITFGTWMYSVNKEQLARAGFYALGEGDKVQCFHCGGGLNDWKPSEDPWEQHAKWFPGCKYLLEEKGEEYVNNIHLTHSIEESLGRTVERAPLLTEIIDDTIFQNPMVQEAIRMGFSFKDIKKTMEGKIQTSGSNYKSLEVLVADLVNAQKDNTQDESSQTSLQKDISTEEQLRLLQEEKLCKICMDRNIAVVFIPCGHLVTCKQCAEAVDKCPMCYTAITLRQKIFMS", "length": 497, "header": "tr|A0ABI0NI58-1|A0ABI0NI58_BOVIN Isoform 1 of E3 ubiquitin-protein ligase XIAP OS=Bos taurus OX=9913 GN=XIAP PE=3 SV=1 CANONICAL=A0ABI0NI58-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NI58-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58/entry#A0ABI0NI58-1", "sequence": { "sequence": "MTFNSFEGSKTCVPADIDKDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAIGRHRRVSPNCRFINGFYFENNAAQPTYSGVQNGQYKAENYLGNRNHFVLERPSETHAHYLLRTGQVVDLSDTVYPRNPVMCSEEARLKSFHNWPDYAHLTPRELARAGLYYTGIDDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNINMQSESSVVSSDRNFPNSTNAPINPAMADYEARIITFGTWMYSVNKEQLARAGFYALGEGDKVQCFHCGGGLNDWKPSEDPWEQHAKWFPGCKYLLEEKGEEYVNNIHLTHSIEESLGRTVERAPLLTEIIDDTIFQNPMVQEAIRMGFSFKDIKKTMEGKIQTSGSNYKSLEVLVADLVNAQKDNTQDESSQTSLQKDISTEEQLRLLQEEKLCKICMDRNIAVVFIPCGHLVTCKQCAEAVDKCPMCYTAITLRQKIFMS", "length": 497, "header": "tr|A0ABI0NI58-1|A0ABI0NI58_BOVIN Isoform 1 of E3 ubiquitin-protein ligase XIAP OS=Bos taurus OX=9913 GN=XIAP PE=3 SV=1 CANONICAL=A0ABI0NI58-1" }, "locus": { "chromosome": "X", "start_pos": 8233734, "end_pos": 8218730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149016.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149016.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103999.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103999.1" } ] } }, { "isoform_ac": "G3MWG5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58/entry#G3MWG5-1", "sequence": { "sequence": "MSTARARPLCQAGAWPPRGVGTSRLGLGPPLLQDPPLSTARGASGDLGRLSWREKVDKSYFQEKMTFNSFEGSKTCVPADIDKDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAIGRHRRVSPNCRFINGFYFENNAAQPTYSGVQNGQYKAENYLGNRNHFVLERPSETHAHYLLRTGQVVDLSDTVYPRNPVMCSEEARLKSFHNWPDYAHLTPRELARAGLYYTGIDDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNINMQSESSVVSSDRNFPNSTNAPINPAMADYEARIITFGTWMYSVNKEQLARAGFYALGEGDKVQCFHCGGGLNDWKPSEDPWEQHAKWFPGCKYLLEEKGEEYVNNIHLTHSIEESLGRTVERAPLLTEIIDDTIFQNPMVQEAIRMGFSFKDIKKTMEGKIQTSGSNYKSLEVLVADLVNAQKDNTQDESSQTSLQKDISTEEQLRLLQEEKLCKICMDRNIAVVFIPCGHLVTCKQCAEAVDKCPMCYTAITLRQKIFMS", "length": 561, "header": "tr|G3MWG5-1|A0ABI0NI58_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase XIAP OS=Bos taurus OX=9913 GN=XIAP PE=3 SV=2 CANONICAL=A0ABI0NI58-1" }, "locus": { "chromosome": "X", "start_pos": 8233734, "end_pos": 8198167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061054.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061054.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053449.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053449.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "X-linked inhibitor of apoptosis protein is an important regulator of vascular endothelial growth factor-dependent bovine aortic endothelial cell survival.", "journal": "Circulation research", "date": "2008-04-25", "authors": "Kim Jongmin, Park Jongbong, Choi Seungmin, Chi Sung-Gil, Mowbray Amy L, Jo Hanjoong, Park Heonyong", "evidence": [ { "database": "RefSeq", "id": "NP_001192521", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192521" } ], "reference": [ { "type": "PubMed", "id": "18309102", "url": "https://glygen.org/publication/PubMed/18309102" } ] }, { "title": "X-linked inhibitor of apoptosis protein controls alpha5-integrin-mediated cell adhesion and migration.", "journal": "American journal of physiology. Heart and circulatory physiology", "date": "2010-08", "authors": "Kim Jongmin, Ahn Sunyoung, Ko Young-Gyu, Boo Yong Chool, Chi Sung-Gil, Ni Chih-Wen, Go Young-Mi, Jo Hanjoong, Park Heonyong", "evidence": [ { "database": "RefSeq", "id": "NP_001192521", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192521" } ], "reference": [ { "type": "PubMed", "id": "20472758", "url": "https://glygen.org/publication/PubMed/20472758" } ] }, { "title": "XIAP is essential for shear stress-enhanced Tyr-576 phosphorylation of FAK.", "journal": "Biochemical and biophysical research communications", "date": "2010-08-20", "authors": "Ahn Sunyoung, Park Heonyong", "evidence": [ { "database": "RefSeq", "id": "NP_001192521", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192521" } ], "reference": [ { "type": "PubMed", "id": "20655298", "url": "https://glygen.org/publication/PubMed/20655298" } ] }, { "title": "XIAP reverses various functional activities of FRNK in endothelial cells.", "journal": "Biochemical and biophysical research communications", "date": "2012-03-09", "authors": "Ahn Sunyoung, Kim Hyun Jeong, Chi Sung-Gil, Park Heonyong", "evidence": [ { "database": "RefSeq", "id": "NP_001192521", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192521" } ], "reference": [ { "type": "PubMed", "id": "22366087", "url": "https://glygen.org/publication/PubMed/22366087" } ] } ], "pathway": [ { "id": "bta:281647", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281647", "resource": "KEGG Pathway" }, { "id": "R-BTA-111459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111459", "resource": "Reactome", "description": "Activation of caspases through apoptosome-mediated cleavage" }, { "id": "R-BTA-111463", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111463", "resource": "Reactome", "description": "SMAC (DIABLO) binds to IAPs" }, { "id": "R-BTA-111464", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111464", "resource": "Reactome", "description": "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" }, { "id": "R-BTA-111469", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111469", "resource": "Reactome", "description": "SMAC, XIAP-regulated apoptotic response" }, { "id": "R-BTA-3769402", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3769402", "resource": "Reactome", "description": "Deactivation of the beta-catenin transactivating complex" }, { "id": "R-BTA-5357786", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357786", "resource": "Reactome", "description": "TNFR1-induced proapoptotic signaling" }, { "id": "R-BTA-5357905", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357905", "resource": "Reactome", "description": "Regulation of TNFR1 signaling" }, { "id": "R-BTA-5357956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357956", "resource": "Reactome", "description": "TNFR1-induced NF-kappa-B signaling pathway" }, { "id": "R-BTA-5675482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5675482", "resource": "Reactome", "description": "Regulation of necroptotic cell death" }, { "id": "R-BTA-8948747", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8948747", "resource": "Reactome", "description": "Regulation of PTEN localization" }, { "id": "R-BTA-8948751", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8948751", "resource": "Reactome", "description": "Regulation of PTEN stability and activity" }, { "id": "R-BTA-9627069", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9627069", "resource": "Reactome", "description": "Regulation of the apoptosome activity" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 19, "go_terms": [ { "name": "nucleotide-binding oligomerization domain containing 1 signaling pathway", "id": "GO:0070427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070427", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "nucleotide-binding oligomerization domain containing 2 signaling pathway", "id": "GO:0070431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070431", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "regulation of apoptosis involved in tissue homeostasis", "id": "GO:0060785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060785", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:0010804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010804", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "positive regulation of type I interferon production", "id": "GO:0032481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032481", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "positive regulation of protein linear polyubiquitination", "id": "GO:1902530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902530", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "regulation of programmed cell death", "id": "GO:0043067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043067", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase inhibitor activity involved in apoptotic process", "id": "GO:0043027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043027", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase inhibitor activity", "id": "GO:0004869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004869", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" }, { "name": "protein serine/threonine kinase binding", "id": "GO:0120283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120283", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NI58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-114252", "name": "Cleavage of Procaspase-3 by the apoptosome", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "F1MB04-1", "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-114252", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114252" } ] }, { "id": "R-BTA-114261", "name": "Cleavage of Procaspase-7 by the apoptosome", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S706-1", "A0ABI0NI58-1", "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-114261", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114261" } ] }, { "id": "R-BTA-114354", "name": "SMAC binds XIAP:Caspase-7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S706-1", "A0ABI0NI58-1" ], "evidence": [ { "id": "R-BTA-114354", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114354" } ] }, { "id": "R-BTA-114392", "name": "Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S706-1", "A0ABI0NI58-1" ], "evidence": [ { "id": "R-BTA-114392", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114392" } ] }, { "id": "R-BTA-3322429", "name": "XIAP monoubiquinates TLE", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1" ], "evidence": [ { "id": "R-BTA-3322429", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3322429" } ] }, { "id": "R-BTA-3322431", "name": "XIAP binds TLE", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1" ], "evidence": [ { "id": "R-BTA-3322431", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3322431" } ] }, { "id": "R-BTA-3322434", "name": "XIAP dissociates from ub-TLE", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1" ], "evidence": [ { "id": "R-BTA-3322434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3322434" } ] }, { "id": "R-BTA-5357757", "name": "BIRC(cIAP1/2) ubiquitinates RIPK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357757", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357757" } ] }, { "id": "R-BTA-5357776", "name": "TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95KV1-1", "Q95KV0-1", "A0ABI0NI58-1", "Q1RMU2-1", "Q2KHV7-1", "A0ABI0NXY8-1", "E1BMK3-1", "G3N2I1-1", "Q5E953-1", "A6QR55-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357776", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357776" } ] }, { "id": "R-BTA-5357780", "name": "TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357780", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357780" } ] }, { "id": "R-BTA-5357845", "name": "K63polyUb-RIPK1 is deubiquitinated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "Q2KHV7-1", "A0ABI0NXY8-1", "G3N2I1-1", "Q5E953-1", "A6QR55-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357845", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357845" } ] }, { "id": "R-BTA-5357860", "name": "TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "Q2KHV7-1", "A0ABI0NXY8-1", "E1BMK3-1", "G3N2I1-1", "Q5E953-1", "A2VDU3-1", "A6QR55-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357860", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357860" } ] }, { "id": "R-BTA-5357904", "name": "TNF:TNFR1:TRADD:TRAF2:RIPK1 binds LUBAC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "E1BMK3-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357904", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357904" } ] }, { "id": "R-BTA-5357928", "name": "CLIP3 and CYLD bind TNF signaling complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357928", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357928" } ] }, { "id": "R-BTA-5675470", "name": "BIRC2/3 (cIAP1/2) is autoubiquitinated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1" ], "evidence": [ { "id": "R-BTA-5675470", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5675470" } ] }, { "id": "R-BTA-5693055", "name": "TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5693055", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5693055" } ] }, { "id": "R-BTA-5693108", "name": "TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5693108", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5693108" } ] }, { "id": "R-BTA-6807106", "name": "PTEN undergoes monoubiquitination", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-BTA-6807247" ], "enzyme_list": [ "A0ABI0NI58-1", "A0AAA9U0H6-1", "F1MJ10-1" ], "evidence": [ { "id": "R-BTA-6807106", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807106" } ] }, { "id": "R-BTA-6807134", "name": "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-BTA-6807280" ], "enzyme_list": [ "A0ABI0NI58-1", "E1B7G3-1", "A0AAA9U0H6-1", "F1MJ10-1" ], "evidence": [ { "id": "R-BTA-6807134", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807134" } ] }, { "id": "R-BTA-83582", "name": "TRADD:TRAF2:RIP1 dissociates from TNF-:TNFR1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TWW0-1", "A0ABI0NI58-1", "F1MQ36-1", "Q1RMU2-1", "E1BMK3-1", "E1B9D9-1", "E1BBN5-1" ], "evidence": [ { "id": "R-BTA-83582", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-83582" } ] }, { "id": "R-BTA-9627078", "name": "XIAP binds CASP9", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "E1BNU2-1" ], "evidence": [ { "id": "R-BTA-9627078", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9627078" } ] }, { "id": "R-BTA-9627104", "name": "XIAP binds CASP3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "F1MB04-1" ], "evidence": [ { "id": "R-BTA-9627104", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9627104" } ] }, { "id": "R-BTA-9627107", "name": "XIAP binds CASP7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S706-1", "A0ABI0NI58-1" ], "evidence": [ { "id": "R-BTA-9627107", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9627107" } ] }, { "id": "R-BTA-9627350", "name": "SMAC (DIABLO) binds XIAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1" ], "evidence": [ { "id": "R-BTA-9627350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9627350" } ] }, { "id": "R-BTA-9627369", "name": "SEPT4 binds XIAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1" ], "evidence": [ { "id": "R-BTA-9627369", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9627369" } ] }, { "id": "R-BTA-9793679", "name": "LUBAC ubiquitinates RIPK1 at K627", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3MHP1-1", "A0ABI0NI58-1", "E1BMK3-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-9793679", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9793679" } ] }, { "id": "R-BTA-9793680", "name": "OPTN binds polyUb-RIPK1 within the TNFR1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "E1BMK3-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-9793680", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9793680" } ] }, { "id": "R-BTA-9796379", "name": "CYLD:SPATA2:LUBAC binds TNFR1 signaling complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "E1BMK3-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-9796379", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9796379" } ] }, { "id": "R-BTA-9817362", "name": "SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3MHP1-1", "A0ABI0NI58-1", "Q1RMU2-1", "E1BMK3-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-9817362", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9817362" } ] }, { "id": "R-BTA-9817397", "name": "TBK1, IKBKE phosphorylate RIPK1 at T189", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TWW0-1", "A0ABI0NI58-1", "F1MQ36-1", "Q1RMU2-1", "E1BMK3-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-9817397", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9817397" } ] }, { "id": "R-BTA-9817400", "name": "CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "E1BMK3-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-9817400", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9817400" } ] }, { "id": "R-BTA-9817411", "name": "TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TWW0-1", "A0ABI0NI58-1", "F1MQ36-1", "Q1RMU2-1", "E1BMK3-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-9817411", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9817411" } ] }, { "id": "R-BTA-9818789", "name": "CHUK, IKBKB phosphorylate RIPK1 at S25", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95KV1-1", "Q95KV0-1", "A0ABI0NI58-1", "Q1RMU2-1", "E1BMK3-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-9818789", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9818789" } ] }, { "id": "R-BTA-9818975", "name": "CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "E1BMK3-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-9818975", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9818975" } ] }, { "id": "R-BTA-9824874", "name": "OPTN recruits CYLD to the TNFR1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "E1BMK3-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-9824874", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9824874" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-6807247", "participant_name": "PTEN [cytosol]", "crossref": [ { "id": "NP_001306827.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAP00000012499", "database": "ENSEMBL", "url": "" }, { "id": "F1MDX9", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000009498", "database": "ENSEMBL", "url": "" }, { "id": "33496", "database": "VGNC", "url": "" }, { "id": "ENSBTAT00000012499", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-BTA-6807280", "participant_name": "PTEN [cytosol]", "crossref": [ { "id": "ENSBTAT00000012499", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAG00000009498", "database": "ENSEMBL", "url": "" }, { "id": "33496", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000012499", "database": "ENSEMBL", "url": "" }, { "id": "F1MDX9", "database": "UniProt", "url": "" }, { "id": "NP_001306827.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9S706", "gene_name": "CASP7", "activity": [ { "ec_number": "3.4.22.56", "activity": "Strict requirement for an Asp residue at positions P1 and P4. It has a preferred cleavage sequence of Asp-Xaa-Xaa-Asp-|- with a hydrophobic amino-acid residue at P2 and a hydrophilic amino-acid residue at P3, although Val or Ala are also accepted at this position.", "evidence": [ { "id": "A0AAA9S706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S706" } ] }, { "ec_number": "3.4.22.56", "activity": "", "evidence": [ { "id": "A0AAA9S706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S706" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0ABI0NI58", "gene_name": "XIAP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0ABI0NI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0ABI0NI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ] } ] }, { "uniprot_ac": "A0ABI0NXY8", "gene_name": "OTUD7B", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A0ABI0NXY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXY8" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A0ABI0NXY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXY8" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A6QR55", "gene_name": "USP4", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A6QR55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QR55" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A6QR55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QR55" } ] } ] }, { "uniprot_ac": "E1B7G3", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] } ] }, { "uniprot_ac": "E1B9D9", "gene_name": "TRAF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D9" } ] } ] }, { "uniprot_ac": "E1BBN5", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] } ] }, { "uniprot_ac": "E1BMK3", "gene_name": "RNF31", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1BMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMK3" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1BMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMK3" } ] } ] }, { "uniprot_ac": "E1BNU2", "gene_name": "CASP9", "activity": [ { "ec_number": "3.4.22.62", "activity": "Strict requirement for an Asp residue at position P1 and with a marked preference for His at position P2. It has a preferred cleavage sequence of Leu-Gly-His-Asp-|-Xaa.", "evidence": [ { "id": "E1BNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ] }, { "ec_number": "3.4.22.62", "activity": "", "evidence": [ { "id": "E1BNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNU2" } ] } ] }, { "uniprot_ac": "F1MB04", "gene_name": "CASP3", "activity": [ { "ec_number": "3.4.22.56", "activity": "Strict requirement for an Asp residue at positions P1 and P4. It has a preferred cleavage sequence of Asp-Xaa-Xaa-Asp-|- with a hydrophobic amino-acid residue at P2 and a hydrophilic amino-acid residue at P3, although Val or Ala are also accepted at this position.", "evidence": [ { "id": "F1MB04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB04" } ] }, { "ec_number": "3.4.22.56", "activity": "", "evidence": [ { "id": "F1MB04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB04" } ] } ] }, { "uniprot_ac": "F1MJ10", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] } ] }, { "uniprot_ac": "F1MQ36", "gene_name": "IKBKE", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ36" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "F1MQ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ36" } ] } ] }, { "uniprot_ac": "G3N2I1", "gene_name": "OTUD1", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "G3N2I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2I1" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "G3N2I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2I1" } ] } ] }, { "uniprot_ac": "Q1RMU2", "gene_name": "CYLD", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "Q1RMU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMU2" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "Q1RMU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMU2" } ] } ] }, { "uniprot_ac": "Q2KHV7", "gene_name": "USP2", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "Q2KHV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KHV7" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "Q2KHV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KHV7" } ] } ] }, { "uniprot_ac": "Q3MHP1", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] } ] }, { "uniprot_ac": "Q5E953", "gene_name": "UFC1", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "Q5E953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E953" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "Q5E953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E953" } ] } ] }, { "uniprot_ac": "Q95KV0", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] } ] }, { "uniprot_ac": "Q95KV1", "gene_name": "CHUK", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 450, "end_pos": 484, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 252, "end_pos": 254 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0ABZ3NNH7-1", "uniprot_ac": "A0ABZ3NNH7", "uniprot_id": "A0ABZ3NNH7_BOVIN", "mass": { "chemical_mass": 73013.0, "monoisotopic_mass": 73013.0 }, "refseq": {}, "gene_names": [ { "name": "KAT7", "type": "recommended", "evidence": [ { "id": "A0ABZ3NNH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7" } ] } ], "protein_names": [ { "name": "Histone acetyltransferase", "type": "recommended", "evidence": [ { "id": "A0ABZ3NNH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.48", "type": "synonym", "evidence": [ { "id": "A0ABZ3NNH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNH7", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KAT7", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7", "locus": { "chromosome": "19", "start_pos": 36811899, "end_pos": 36846612, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018699", "url": "https://www.ensembl.org/id/ENSBTAG00000018699" } ] } } ], "crossref": [ { "id": "ENSBTAG00000018699", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018699", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "508246", "url": "https://www.ncbi.nlm.nih.gov/gene/508246", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:508246", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508246", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EIGRYEM", "url": "https://omabrowser.org/oma/group/EIGRYEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10615:SF161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10615:SF161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17772", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17772", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "45948", "url": "https://www.rhea-db.org/rhea/45948", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S3N2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3N2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY89", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY89-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1J7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1J7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1J7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3F9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3F9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3F9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKR7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKR7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TL56", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TL56-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABZ3NNH7", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABZ3NNH7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "TEPAGATVPAAAAAARIITVGPQQPAMPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPSERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADSTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "length": 637, "header": "tr|A0ABZ3NNH7-1|A0ABZ3NNH7_BOVIN Isoform 1 of Histone acetyltransferase OS=Bos taurus OX=9913 GN=KAT7 PE=3 SV=1 CANONICAL=A0ABZ3NNH7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S3N2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7/entry#A0AAA9S3N2-1", "sequence": { "sequence": "MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPSERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADSTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "length": 547, "header": "tr|A0AAA9S3N2-1|A0ABZ3NNH7_BOVIN Computationally mapped isoform of Histone acetyltransferase OS=Bos taurus OX=9913 GN=KAT7 PE=3 SV=1 CANONICAL=A0ABZ3NNH7-1" }, "locus": { "chromosome": "19", "start_pos": 36846517, "end_pos": 36813463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115124.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115124.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077875.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077875.1" } ] } }, { "isoform_ac": "A0AAA9SY89-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7/entry#A0AAA9SY89-1", "sequence": { "sequence": "MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPSERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADSTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "length": 531, "header": "tr|A0AAA9SY89-1|A0ABZ3NNH7_BOVIN Computationally mapped isoform of Histone acetyltransferase OS=Bos taurus OX=9913 GN=KAT7 PE=3 SV=1 CANONICAL=A0ABZ3NNH7-1" }, "locus": { "chromosome": "19", "start_pos": 36846517, "end_pos": 36813463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098468.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098468.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091428.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091428.1" } ] } }, { "isoform_ac": "A0AAA9T1J7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7/entry#A0AAA9T1J7-1", "sequence": { "sequence": "MEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADSTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "length": 264, "header": "tr|A0AAA9T1J7-1|A0ABZ3NNH7_BOVIN Computationally mapped isoform of Histone acetyltransferase OS=Bos taurus OX=9913 GN=KAT7 PE=3 SV=2 CANONICAL=A0ABZ3NNH7-1" }, "locus": { "chromosome": "19", "start_pos": 36827514, "end_pos": 36813463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124278.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124278.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090275.2", "url": "https://www.ensembl.org/id/ENSBTAP00000090275.2" } ] } }, { "isoform_ac": "A0AAA9T3F9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7/entry#A0AAA9T3F9-1", "sequence": { "sequence": "MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPSERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADSTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "length": 581, "header": "tr|A0AAA9T3F9-1|A0ABZ3NNH7_BOVIN Computationally mapped isoform of Histone acetyltransferase OS=Bos taurus OX=9913 GN=KAT7 PE=3 SV=1 CANONICAL=A0ABZ3NNH7-1" }, "locus": { "chromosome": "19", "start_pos": 36846517, "end_pos": 36813463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125756.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125756.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092306.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092306.1" } ] } }, { "isoform_ac": "A0AAA9TKR7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7/entry#A0AAA9TKR7-1", "sequence": { "sequence": "MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPSERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADSTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "length": 472, "header": "tr|A0AAA9TKR7-1|A0ABZ3NNH7_BOVIN Computationally mapped isoform of Histone acetyltransferase OS=Bos taurus OX=9913 GN=KAT7 PE=3 SV=1 CANONICAL=A0ABZ3NNH7-1" }, "locus": { "chromosome": "19", "start_pos": 36846517, "end_pos": 36813463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108902.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108902.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099038.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099038.1" } ] } }, { "isoform_ac": "A0AAA9TL56-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7/entry#A0AAA9TL56-1", "sequence": { "sequence": "MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADSTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "length": 548, "header": "tr|A0AAA9TL56-1|A0ABZ3NNH7_BOVIN Computationally mapped isoform of Histone acetyltransferase OS=Bos taurus OX=9913 GN=KAT7 PE=3 SV=1 CANONICAL=A0ABZ3NNH7-1" }, "locus": { "chromosome": "19", "start_pos": 36846517, "end_pos": 36813463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091748.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091748.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097019.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097019.1" } ] } }, { "isoform_ac": "A0ABZ3NNH7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7/entry#A0ABZ3NNH7-1", "sequence": { "sequence": "TEPAGATVPAAAAAARIITVGPQQPAMPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPSERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADSTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT", "length": 637, "header": "tr|A0ABZ3NNH7-1|A0ABZ3NNH7_BOVIN Isoform 1 of Histone acetyltransferase OS=Bos taurus OX=9913 GN=KAT7 PE=3 SV=1 CANONICAL=A0ABZ3NNH7-1" }, "locus": { "chromosome": "19", "start_pos": 36846595, "end_pos": 36813463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024887.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024887.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024887.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024887.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:508246", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508246", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNH7", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNH7", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNH7", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7" } ], "pmid": "" }, { "name": "histone H3-K14 acetyltransferase complex", "id": "GO:0036409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036409", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNH7", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNH7", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNH7", 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May also play a role in cell-cell adhesion and contact inhibition in epithelial cells.", "evidence": [ { "database": "UniProtKB", "id": "E1BF45", "url": "https://www.uniprot.org/uniprotkb/E1BF45#function" }, { "database": "UniProtKB", "id": "ARBA00059631", "url": "https://www.uniprot.org/uniprotkb/ARBA00059631#function" }, { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88#function" }, { "database": "UniProtKB", "id": "A0ABI0P1F3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1F3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CDHR2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88", "locus": { "chromosome": "7", "start_pos": 38070255, "end_pos": 38024566, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025340", "url": "https://www.ensembl.org/id/ENSBTAG00000025340" } ] } } ], "crossref": [ { "id": "ENSBTAG00000025340", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000025340", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "511921", "url": "https://www.ncbi.nlm.nih.gov/gene/511921", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QTVMLVQ", "url": "https://omabrowser.org/oma/group/QTVMLVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24026:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24026:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010805431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010805431", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ88-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1F3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1F3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1F3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF45", "url": "https://www.uniprot.org/uniprotkb/E1BF45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF45-1", "url": "https://www.uniprot.org/uniprotkb/E1BF45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMIRRACVYRERVSPVTRRRQDSVKPRALAWQGEGALDRGGRGVEWRVEQEPEPPWDSGLKGLTALSSLPRNEVPPDMMGWPWLSCLLFPALVVSVAANTAPMFASNMSTVSLPEDLPVGAEAFWLVAQDQDNDELKYGISGSNAYFFNVTSNTGEVKLASPLDYETLYWFAITISVSDSYNNQVQREMQVIVEDRNDNAPVFQSISFSANVSETLPVGSLVLSVQATDKDTGSAGAVVYSIEKVIPATEGSEYLFRVLPNGSIILNGSLDYNSKSSFYQLELRACDSGGLYNNHTVIQCSSSVFVSISVIDKPDLDPQFVREFYSASVAEDTPQGTSVLKVEAMDGDRGINDPVIYSISNSTRPGWFDIGKQDGVITVNSPLDREQLLEEDEEVQVQVTATETHPNIHGQEAKASIWVTLRVTDVNDHVPEFYNCSLQDCAFTPNETQVNFTGYVDEHASTRIPIEDLTMVVYDPDKGSNGTFLLTLGGPDAEAFSVSPQRAAGSVDVQVLVREPSLVDYERQSVMLVQVTATDSVSGNASVASVTIHLRDTNDHRPTFPSSMYNLSVFEHSPVGYVVTDSIRASDPDTGEGGRVTYSLLPGNGADIFAVDPDSGKVTVRNSELLDREKQAVYYLTLQATDGGNLSSSTTLQIHVLDVNDNSPMVSGSYNIFVQEEEGNVSVTIQAHDNDQPDTNNSLLHFSLLPSPFSHNFSVDPDKGILRNLGPLDREAIDPALGGRIVLSVNVSDSGEPALWTTVSVTITVEDINDNLPIFNQSRYSFSVRERDPGVQVGMVEAWDADQTEANNRISFSLSGSGANNFMIRGSVLGSGQAVGRLSLPLDVSLDYETQASFSLIVSAENADAQGRETTAEVLVTVGDVNDVPPTLDSASLQGIRVAENGSQHGILVNVVAQDRDTMSQVEVQLVNVICTKAGVDVGSLCHGWFSVLANGSVIINQSEAIDYEACDLVTLVVRAYDLTTDPRFQAYSDNGSLPITIEDVNDNAPYFLPEDKTFVIIPELVMPNQQVASVRARDDDSGNNAAILFSIFQVDFIAKDGAVIPFQGFFRVSTSSEASVFTGNIDLVTSLDSTLQGTYQVTVKAQDSPSEGPAQEARITLNLFTVDQSYRVRLQFSLNKEEVGANSEKIKEALAQATRTTVYIVNIQDIDSQVRARGRSYLDAYFVFSNGSALTLDQLSMMIRNDQDSLTQLLQLGLVVLGSQDNQESESQDTLRNVTIGLGVALLLAIVIFSTIIMCTQKSYQRKLRAMKAAKEARKTAVGVMPPGSAIPGTNMYNTERANPMLNLPAKDLGFESHSSSSDLDYISVNSLDDNSVDLENSAQEIKKEPPHGPMGPHPEPRKNELSGRKVGSEQKEELAFTNLGLDTTDL", "length": 1388, "header": "tr|A0ABI0NJ88-1|A0ABI0NJ88_BOVIN Isoform 1 of Cadherin-related family member 2 OS=Bos taurus OX=9913 GN=CDHR2 PE=4 SV=1 CANONICAL=A0ABI0NJ88-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NJ88-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88/entry#A0ABI0NJ88-1", "sequence": { "sequence": "MMIRRACVYRERVSPVTRRRQDSVKPRALAWQGEGALDRGGRGVEWRVEQEPEPPWDSGLKGLTALSSLPRNEVPPDMMGWPWLSCLLFPALVVSVAANTAPMFASNMSTVSLPEDLPVGAEAFWLVAQDQDNDELKYGISGSNAYFFNVTSNTGEVKLASPLDYETLYWFAITISVSDSYNNQVQREMQVIVEDRNDNAPVFQSISFSANVSETLPVGSLVLSVQATDKDTGSAGAVVYSIEKVIPATEGSEYLFRVLPNGSIILNGSLDYNSKSSFYQLELRACDSGGLYNNHTVIQCSSSVFVSISVIDKPDLDPQFVREFYSASVAEDTPQGTSVLKVEAMDGDRGINDPVIYSISNSTRPGWFDIGKQDGVITVNSPLDREQLLEEDEEVQVQVTATETHPNIHGQEAKASIWVTLRVTDVNDHVPEFYNCSLQDCAFTPNETQVNFTGYVDEHASTRIPIEDLTMVVYDPDKGSNGTFLLTLGGPDAEAFSVSPQRAAGSVDVQVLVREPSLVDYERQSVMLVQVTATDSVSGNASVASVTIHLRDTNDHRPTFPSSMYNLSVFEHSPVGYVVTDSIRASDPDTGEGGRVTYSLLPGNGADIFAVDPDSGKVTVRNSELLDREKQAVYYLTLQATDGGNLSSSTTLQIHVLDVNDNSPMVSGSYNIFVQEEEGNVSVTIQAHDNDQPDTNNSLLHFSLLPSPFSHNFSVDPDKGILRNLGPLDREAIDPALGGRIVLSVNVSDSGEPALWTTVSVTITVEDINDNLPIFNQSRYSFSVRERDPGVQVGMVEAWDADQTEANNRISFSLSGSGANNFMIRGSVLGSGQAVGRLSLPLDVSLDYETQASFSLIVSAENADAQGRETTAEVLVTVGDVNDVPPTLDSASLQGIRVAENGSQHGILVNVVAQDRDTMSQVEVQLVNVICTKAGVDVGSLCHGWFSVLANGSVIINQSEAIDYEACDLVTLVVRAYDLTTDPRFQAYSDNGSLPITIEDVNDNAPYFLPEDKTFVIIPELVMPNQQVASVRARDDDSGNNAAILFSIFQVDFIAKDGAVIPFQGFFRVSTSSEASVFTGNIDLVTSLDSTLQGTYQVTVKAQDSPSEGPAQEARITLNLFTVDQSYRVRLQFSLNKEEVGANSEKIKEALAQATRTTVYIVNIQDIDSQVRARGRSYLDAYFVFSNGSALTLDQLSMMIRNDQDSLTQLLQLGLVVLGSQDNQESESQDTLRNVTIGLGVALLLAIVIFSTIIMCTQKSYQRKLRAMKAAKEARKTAVGVMPPGSAIPGTNMYNTERANPMLNLPAKDLGFESHSSSSDLDYISVNSLDDNSVDLENSAQEIKKEPPHGPMGPHPEPRKNELSGRKVGSEQKEELAFTNLGLDTTDL", "length": 1388, "header": "tr|A0ABI0NJ88-1|A0ABI0NJ88_BOVIN Isoform 1 of Cadherin-related family member 2 OS=Bos taurus OX=9913 GN=CDHR2 PE=4 SV=1 CANONICAL=A0ABI0NJ88-1" }, "locus": { "chromosome": "7", "start_pos": 38069251, "end_pos": 38027419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144534.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144534.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104157.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104157.1" } ] } }, { "isoform_ac": "A0ABI0P1F3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88/entry#A0ABI0P1F3-1", "sequence": { "sequence": "MMIRRACVYRERVSPVTRRRQDSVKPRALAWQGEGALDRGGRGVEWRVEQEPEPPWDSGLKGLTALSSLPRNEVPPDMMGWPWLSCLLFPALVVSVAANTAPMFASNMSTVSLPEDLPVGAEAFWLVAQDQDNDELKYGISGSNAYFFNVTSNTGEVKLASPLDYETLYWFAITISVSDSYNNQVQREMQVIVEDRNDNAPVFQSISFSANVSETLPVGSLVLSVQATDKDTGSAGAVVYSIEKVIPATEGSEYLFRVLPNGSIILNGSLDYNSKSSFYQLELRACDSGGLYNNHTVIQCSSSVFVSISVIDKPDLDPQFVREFYSASVAEDTPQGTSVLKVEAMDGDRGINDPVIYSISNSTRPGWFDIGKQDGVITVNSPLDREQLLEEDEEVQVQVTATETHPNIHGQEAKASIWVTLRVTDVNDHVPEFYNCSLQDCAFTPNETQVNFTGYVDEHASTRIPIEDLTMVVYDPDKGSNGTFLLTLGGPDAEAFSVSPQRAAGSVDVQVLVREPSLVDYERQSVMLVQVTATDSVSGNASVASVTIHLRDTNDHRPTFPSSMYNLSVFEHSPVGYVVTDSIRASDPDTGEGGRVTYSLLPGNGADIFAVDPDSGKVTVRNSELLDREKQAVYYLTLQATDGGNLSSSTTLQIHVLDVNDNSPMVSGSYNIFVQEEEGNVSVTIQAHDNDQPDTNNSLLHFSLLPSPFSHNFSVDPDKGILRNLGPLDREAIDPALGGRIVLSVNVSDSGEPALWTTVSVTITVEDINDNLPIFNQSRYSFSVRERDPGVQVGMVEAWDADQTEANNRISFSLSGSGANNFMIRGSVLGSGQAVGRLSLPLDVSLDYETQASFSLIVSAENADAQGRETTAEVLVTVGDVNDVPPTLDSASLQGIRVAENGSQHGILVNVVAQDRDTMSQVEVQLVNVICTKAGVDVGSLCHGWFSVLANGSVIINQSEAIDYEACDLVTLVVRAYDLTTDPRFQAYSDNGSLPITIEDVNDNAPYFLPEDKTFVIIPELVMPNQQVASVRARDDDSGNNAAILFSIFQVDFIAKDGAVIPFQGFFRVSTSSEASVFTGNIDLVTSLDSTLQGTYQVTVKAQDSPSEGPAQEARITLNLFTVDQSYRVRLQFSLNKEEVGANSEKIKEALAQATRTTVYIVNIQDIDSQVRARGRSYLDAYFVFSNGSALTLDQLSMMIRNDQDSLTQLLQLGLVVLGSQDNQESESQDTLRNVTIGLGVALLLAIVIFSTIIMCTQKSYQRKLRAMKAAKEARKTAVGVMPPGSAIPGTNMYNTERANPMLNLPAKDLGFESHSSSSDLDYISVNSLDDNSVDLENSAQEIKARWGMSWYLGFLT", "length": 1357, "header": "tr|A0ABI0P1F3-1|A0ABI0P1F3_BOVIN Computationally mapped isoform of Cadherin-related family member 2 OS=Bos taurus OX=9913 GN=CDHR2 PE=4 SV=1 CANONICAL=A0ABI0NJ88-1" }, "locus": { "chromosome": "7", "start_pos": 38066160, "end_pos": 38027419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137719.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137719.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104189.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104189.1" } ] } }, { "isoform_ac": "E1BF45-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88/entry#E1BF45-1", "sequence": { "sequence": "MVPKSADCATAGPRRCPPGPSTHLLPPGPLLGAQVPPDMMGWPWLSCLLFPALVVSVAANTAPMFASNMSTVSLPEDLPVGAEAFWLVAQDQDNDELKYGISGSNAYFFNVTSNTGEVKLASPLDYETLYWFAITISVSDSYNNQVQREMQVIVEDRNDNAPVFQSISFSANVSETLPVGSLVLSVQATDKDTGSAGAVVYSIEKVIPATEGSEYLFRVLPNGSIILNGSLDYNSKSSFYQLELRACDSGGLYNNHTVIQCSSSVFVSISVIDKPDLDPQFVREFYSASVAEDTPQGTSVLKVEAMDGDRGINDPVIYSISNSTRPGWFDIGKQDGVITVNSPLDREQLLEEDEEVQVQVTATETHPNIHGQEAKASIWVTLRVTDVNDHVPEFYNCSLQDCAFTPNETQVNFTGYVDEHASTRIPIEDLTMVVYDPDKGSNGTFLLTLGGPDAEAFSVSPQRAAGSVDVQVLVREPSLVDYERQSVMLVQVTATDSVSGNASVASVTIHLRDTNDHRPTFPSSMYNLSVFEHSPVGYVVTDSIRASDPDTGEGGRVTYSLLPGNGADIFAVDPDSGKVTVRNSELLDREKQAVYYLTLQATDGGNLSSSTTLQIHVLDVNDNSPMVSGSYNIFVQEEEGNVSVTIQAHDNDQPDTNNSLLHFSLLPSPFSHNFSVDPDKGILRNLGPLDREAIDPALGGRIVLSVNVSDSGEPALWTTVSVTITVEDINDNLPIFNQSRYSFSVRERDPGVQVGMVEAWDADQTEANNRISFSLSGSGANNFMIRGSVLGSGQAVGRLSLPLDVSLDYETQASFSLIVSAENADAQGRETTAEVLVTVGDVNDVPPTLDSASLQGIRVAENGSQHGILVNVVAQDRDTMSQVEVQLVNVICTKAGVDVGSLCHGWFSVLANGSVIINQSEAIDYEACDLVTLVVRAYDLTTDPRFQAYSDNGSLPITIEDVNDNAPYFLPEDKTFVIIPELVMPNQQVASVRARDDDSGNNAAILFSIFQVDFIAKDGAVIPFQGFFRVSTSSEASVFTGNIDLVTSLDSTLQGTYQVTVKAQDSPSEGPAQEARITLNLFTVDQSYRVRLQFSLNKEEVGANSEKIKEALAQATRTTVYIVNIQDIDSQVRARGRSYLDAYFVFSNGSALTLDQLSMMIRNDQDSLTQLLQLGLVVLGSQDNQESESQDTLRNVTIGLGVALLLAIVIFSTIIMCTQKSYQRKLRAMKAAKEARKTAVGVMPPGSAIPGTNMYNTERANPMLNLPAKDLGFESHSSSSDLDYISVNSLDDNSVDLENSAQEIKKEPPHGPMGPHPEPRKNELSGRKVGSEQKEELAFTNLGLDTTDL", "length": 1349, "header": "tr|E1BF45-1|A0ABI0NJ88_BOVIN Computationally mapped isoform of Cadherin-related family member 2 OS=Bos taurus OX=9913 GN=CDHR2 PE=4 SV=3 CANONICAL=A0ABI0NJ88-1" }, "locus": { "chromosome": "7", "start_pos": 38069251, "end_pos": 38024579, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035552.7", "url": "https://www.ensembl.org/id/ENSBTAT00000035552.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000035423.5", "url": "https://www.ensembl.org/id/ENSBTAP00000035423.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y4A1-1", "protein_name": "Cadherin-related family member 2", "gene_name": "CDHR2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHRAPLAAALGRCPPVSWSQSSAVLPGCKRSGAAGSIPARWLQTLSRMAWHPLLLLPFLLAAASGNTAPIFNMTIVYVAEDLQIGEFAFQLMAYDIDGDTITYSISGSDSFYFTANAQTGVVTLRNLLDRESQARLTILVTVSDGINEAVSRRLPIIVEDRNDNAPVFQNLPYETSVLENTTVGSVIYTVFANDSDTGTAARVSYSIQEVIPDTTKNHRLFYILSSGSVVLNNSLDYTMNTFFQLKILAQDGGGLLRNETVIQSSTTYLSITVIDVPNLDPRFLNEPYSGSVPEDCPVGTTVLTVTAMDRDTGVNDKISYSFTNASVPFAINDTTGTITVSQVLDREQLPSEEVLLEVLARESNLDIYGNVAQASTLVTVLVTDVNDNKPQFYQCSSNCNFIHTQSNFTGSIIEHSSSKVPVSNLSIVARDPDKGTNGTFELYLQGTSASAFTVSPTRIVGTGEVQILVQNPSAVDYEITHVMVVQLIANDTGNPTDCCSTATVTIDLIDTNDHIPEFPQSTYNLRVMENSPDGTIIATNITAYDPDSGASGQITYQLLPESIQEIFMVNATSGAVLVRNGSLLDREMRPVYYANLQAKDGGNMMGTTLLEITVLDKNDNEPIIIGSYFISVEEGQNVSTQIRAIDNDEEGTPNSELGFKIVPGLYSNNFTISQTTGELHNIEPLDREAVDDEAGQMVVTVEVYDHGVPQLSTMVNVTITVADVNDNTPVFLQQSYEFSIFESSDGSFVGDVMATDADRTEINSRISFQLEKSTGSSTFLISSSRLGPGNYSGRLSLNPGVSVDYEAMQEKLFSLVVLAENTAADNAGNIANVSVLVNILDVNDEPPTIVPSSLEGVSVRENGTQQDLVHTVFASDRDTNHSLVFEELSVACYKGGSSAGEVCWDWFVLLPNGSVLANSFDIDYELCDVVQLTMRVEDLYTQKGNQYSQNETLQIRIIDINDNAPVFLPVSGTFVVVPEISPVDLQVATVKATDADSGLEGTVFFNIISVVLVQEDGVKRPFENLFKVVTSADQDSYIGSIQVASNLDSSLKGQYQVTVEARDSAAPQQATQTTLIIFTVDQSYRIHLQFVTTVDEVQSNLESIRLALTSATKAGVYVAAIRSYDDSRATQVKAKSVMEVYFVYSNGTALDVNQLSLFIHSDPLVLANLMNLGLAVIGPAEVTEPSKEKEMIGVIAGLAAFLVLFILIAILALVLTIRSYKRKLSAMKALKAATTLSPAVVQGAGIPGTNKYNAERANPMLNLSLDPSHDLGFHEETSSLASINSLDENKVDSPKEDNFKAKRGSPHPTDSTEDEVLAAALNMKEPPKMAYINTAFNTTDL", "length": 1341 }, "evidence": [ { "id": "A0ABI0NJ88", "url": "https://omabrowser.org/oma/group/A0ABI0NJ88/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZAN2-1", "protein_name": "Cadherin-related family member 2", "gene_name": "Cdhr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWLWLLCVLLPTFMVSVTANSLPVFESNMTLVLLPEDLPVGAVVFWLVATDPDGDQLTYGISGLHANYFSVTSNTGEVKLVSSLDFETLPSFRITISVNDGHNVQVTKEMQVIVEDRNDNAPVFLNTEFSTSIKETLPVGSVVFSVLAEDKDTGSSGLVEYFIEKVIPSTDNSKDLFRILVNGSIVLNDTLSYNNKSAFYQLELKACDSGGLLNNTLVTQCSQPVFVSISVIDEPDLDPQFVREFYSASVSEDATLGTSVLAVEAVDSDKGVNYNVTYNITNSTRPGWFCIEKDGVITVCGPLDREQLLLDNEEVQIQVTATEEKPNIYQQEAKVSTWVTIKVTDVNDHKPEFYNCSLQNCTFSPQEAQDNFTGYVDEHASARISIDGLTMVAYDPDQGANGTFLLSLNGTDAEAFNVSPERAAVSVSVQVVVKNSEMVDYEKKTEMQVQVVATDSVSGNYSVATVTIHLRNINDHRPVFSKSLYELTVPENSPTGFLVTDSIEATDLDGDEWGPITYSLLPGAGEDLFEVEPKSGNVTVKNGTLLDREKQAMYYLTMQATDGGNQSTTTMLQITLLDVNDNPPVVRGSYNIFVPEEDGDVSVTIQAYDDDQPGTNNSRLLFSLLPGSYSQNFSIDPDTGLLRNLEPLDREAIDPALEGRIVLTVHVADCGEPSLSTDVNVTITVEDINDNLPIFNQSSYEFFVMERVPGALVGTVKAWDADQTAANNRISFSLSGTGANNFILQSIVLALGWAEGHLWLLPDVSLDYETQKLFNLTVSAENPGPQGLESTANITVVVVDVNDEPPTLDAVSLQSISVAENGSEHGQVAQVIAQDVDTNALLRIELVDVLCTKAGVDVGSVCHGWFSVDTNGSVYINQSEAIDYEVCHLVTLVVRAQDLATDLGFDAYSSNGSLLINIKDKNDNTPYFLPNNQTFVIIPELVLPNQQVASVQARDEDSEDNGIIKFSILKADFVPKDGATNPVQVFRISQSVEAGLYTGSIELVTNLDSTLQGTYQVTVQAQDQPAMDPALETQTTLNLFTVDQSYRVRLQFSTSREDVGANMEEIKAALIQATRTSVYVVTIQNIDSMARARVNSYMDAYFVFSNGSALTLTELNVMIRKDQDALRQLLQLGLVVVSSQETQEFNQTQLLTNVIIGLVVSLVLVLVIMITALVCFRKSYHRKLRAMKAGKEARKTPIETMTPAAAIPGTNVYNTDRANPMLDLPTKDLGLECHSSSDLDYHSLNSLDENSVDLDTDSKEFKRKDLPHNPPESDSEPLTAALSGRSAGTSGQQQRELSFTNPGLDTTDL", "length": 1310 }, "evidence": [ { "id": "A0ABI0NJ88", "url": "https://omabrowser.org/oma/group/A0ABI0NJ88/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q7P9-1", "protein_name": "Cadherin-related family member 2", "gene_name": "Cdhr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1308 }, "evidence": [ { "id": "A0ABI0NJ88", "url": "https://omabrowser.org/oma/group/A0ABI0NJ88/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BYE9-1", "protein_name": "Cadherin-related family member 2", "gene_name": "CDHR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1310 }, "evidence": [ { "id": "A0ABI0NJ88", "url": "https://omabrowser.org/oma/group/A0ABI0NJ88/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "epithelium development", "id": "GO:0060429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060429", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "cell-cell junction assembly", "id": "GO:0007043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007043", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "adherens junction organization", "id": "GO:0034332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034332", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "microvillus membrane", "id": "GO:0031528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031528", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1187, "end_pos": 1189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1234, "end_pos": 1236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 696, "end_pos": 698, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" }, { "start_pos": 901, "end_pos": 903, "annotation": "n_glycosylation_sequon" }, { "start_pos": 951, "end_pos": 953, "annotation": "n_glycosylation_sequon" }, { "start_pos": 957, "end_pos": 959, "annotation": "n_glycosylation_sequon" }, { "start_pos": 991, "end_pos": 993, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NJ88", "database": "UniProtKB", "url": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NKM3-1", "uniprot_ac": "A0ABI0NKM3", "uniprot_id": "A0ABI0NKM3_BOVIN", "mass": { "chemical_mass": 135008.0, "monoisotopic_mass": 135008.0 }, "refseq": { "ac": "XP_005202915", "name": "anion exchange protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005202915" }, "gene_names": [ { "name": "SLC4A3", "type": "recommended", "evidence": [ { "id": "A0ABI0NKM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ] }, { "name": "SLC4A3", "type": "synonym", "evidence": [ { "id": "XP_005202915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005202915" } ] } ], "protein_names": [ { "name": "Anion exchange protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NKM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3/entry#names_and_taxonomy" } ] }, { "name": "anion exchange protein 3", "type": "synonym", "evidence": [ { "id": "XP_005202915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005202915" } ] }, { "name": "solute carrier family 4, anion exchanger, member 3", "type": "synonym", "evidence": [ { "id": "XP_005202915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005202915" } ] } ], "function": [ { "annotation": "Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane. May be involved in the regulation of intracellular pH, and the modulation of cardiac action potential.", "evidence": [ { "database": "UniProtKB", "id": "E1BKK3", "url": "https://www.uniprot.org/uniprotkb/E1BKK3#function" }, { "database": "UniProtKB", "id": "ARBA00045591", "url": "https://www.uniprot.org/uniprotkb/ARBA00045591#function" }, { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC4A3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3", "locus": { "chromosome": "2", "start_pos": 107563067, "end_pos": 107549176, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014975", "url": "https://www.ensembl.org/id/ENSBTAG00000014975" } ] } } ], "crossref": [ { "id": "ENSBTAG00000014975", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014975", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "535049", "url": "https://www.ncbi.nlm.nih.gov/gene/535049", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:535049", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535049", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BKK3", "url": "https://www.orthodb.org/?gene=E1BKK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11453:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11453:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00955", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00955", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07565", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07565", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-425381", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-425381", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005202915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005202915", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "72363", "url": "https://www.rhea-db.org/rhea/72363", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKM3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKK3", "url": "https://www.uniprot.org/uniprotkb/E1BKK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKK3-1", "url": "https://www.uniprot.org/uniprotkb/E1BKK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANGVIPPPGGASPLPQVRVPLEEPPLSPDMEEDDDLGKTLAVSRFGDLISKPPAWDPEKPSRSYSERDFEFHRHTSHHTHHPLSARLPPPHKLRRLPPTSARQTRRKRKKEKTSAPPSEGTPPIQEEGGAGVDEEEEEEEEEGESEAEPAEPPPPGSPTKAKFSIGSDEDDSPSLSGRAAFTKPLPSVGPSSDKSPQHSVSSPSPRARVSRITGEKGRPWSPSASYDLRERLCPGSALGGPGSPEQQVPTDEAEAQMLGSADLDDMKSHRLEDNPGMRRHLVKKPSRTQSGRGSASGLAPILRRKKKQQQLDRRPHEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFPRNASSSSVNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPEAKEKPLHMPGGDGHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEVEGRDLLRSVAAFQRELLRKRREREQTKPELTTQGGYVAPGKELSMELGGSEATPDDDPLLRTGSVFGGLVRDVKRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFHKLYKVFTEHPLLPFYPPEGALEAELDLNASALPPTEGPPGPRNQPNTALLSLILMLGTFLIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPSKRTWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFVLLLTVPLRRCLLPRLFQDRELQALDSEDAEPNFDEDGQDEYNELHMPV", "length": 1226, "header": "tr|A0ABI0NKM3-1|A0ABI0NKM3_BOVIN Isoform 1 of Anion exchange protein OS=Bos taurus OX=9913 GN=SLC4A3 PE=3 SV=1 CANONICAL=A0ABI0NKM3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NKM3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3/entry#A0ABI0NKM3-1", "sequence": { "sequence": "MANGVIPPPGGASPLPQVRVPLEEPPLSPDMEEDDDLGKTLAVSRFGDLISKPPAWDPEKPSRSYSERDFEFHRHTSHHTHHPLSARLPPPHKLRRLPPTSARQTRRKRKKEKTSAPPSEGTPPIQEEGGAGVDEEEEEEEEEGESEAEPAEPPPPGSPTKAKFSIGSDEDDSPSLSGRAAFTKPLPSVGPSSDKSPQHSVSSPSPRARVSRITGEKGRPWSPSASYDLRERLCPGSALGGPGSPEQQVPTDEAEAQMLGSADLDDMKSHRLEDNPGMRRHLVKKPSRTQSGRGSASGLAPILRRKKKQQQLDRRPHEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFPRNASSSSVNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPEAKEKPLHMPGGDGHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEVEGRDLLRSVAAFQRELLRKRREREQTKPELTTQGGYVAPGKELSMELGGSEATPDDDPLLRTGSVFGGLVRDVKRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFHKLYKVFTEHPLLPFYPPEGALEAELDLNASALPPTEGPPGPRNQPNTALLSLILMLGTFLIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPSKRTWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFVLLLTVPLRRCLLPRLFQDRELQALDSEDAEPNFDEDGQDEYNELHMPV", "length": 1226, "header": "tr|A0ABI0NKM3-1|A0ABI0NKM3_BOVIN Isoform 1 of Anion exchange protein OS=Bos taurus OX=9913 GN=SLC4A3 PE=3 SV=1 CANONICAL=A0ABI0NKM3-1" }, "locus": { "chromosome": "2", "start_pos": 107562817, "end_pos": 107549312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154852.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154852.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105341.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105341.1" } ] } }, { "isoform_ac": "E1BKK3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3/entry#E1BKK3-1", "sequence": { "sequence": "MANGVIPPPGGASPLPQVRVPLEEPPLSPDMEEDDDLGKTLAVSRFGDLISKPPAWDPEKPSRSYSERDFEFHRHTSHHTHHPLSARLPPPHKLRRLPPTSARQTRRKRKKEKTSAPPSEGTPPIQEEGGAGVDEEEEEEEEEGESEAEPAEPPPPGSPTKAKFSIGSDEDDSPSLSGRAAFTKPLPSVGPSSDKSPQHSSSPVPSWGRAGEPPHLAHLHRASLPSSRLPCCLLSSPSPRARVSRITGEKGRPWSPSASYDLRERLCPGSALGGPGSPEQQVPTDEAEAQMLGSADLDDMKSHRLEDNPGMRRHLVKKPSRTQSGRGSASGLAPILRRKKKQQQLDRRPHEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFPRNASSSSVNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPEAKEKPLHMPGGDGHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEVEGRDLLRSVAAFQRELLRKRREREQTKPELTTQGGYVAPGKELSMELGGSEATPDDDPLLRTGSVFGGLVRDVKRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFHKLYKVFTEHPLLPFYPPEGALEAELDLNASALPPTEGPPGPRNQPNTALLSLILMLGTFLIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPSKRTWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFVLLLTVPLRRCLLPRLFQDRELQALDSEDAEPNFDEDGQDEYNELHMPV", "length": 1259, "header": "tr|E1BKK3-1|A0ABI0NKM3_BOVIN Computationally mapped isoform of Anion exchange protein OS=Bos taurus OX=9913 GN=SLC4A3 PE=3 SV=2 CANONICAL=A0ABI0NKM3-1" }, "locus": { "chromosome": "2", "start_pos": 107562817, "end_pos": 107549312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019936.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019936.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019936.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019936.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 122, "start_aa": "Thr", "end_pos": 122, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr122", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 667, "start_aa": "Thr", "end_pos": 667, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr667", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:535049", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535049", "resource": "KEGG Pathway" }, { "id": "R-BTA-425381", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-425381", "resource": "Reactome", "description": "Bicarbonate transporters" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" }, { "name": "chloride:bicarbonate antiporter activity", "id": "GO:0140900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140900", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" }, { "name": "monoatomic anion transmembrane transporter activity", "id": "GO:0008509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008509", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" }, { "name": "solute:inorganic anion antiporter activity", "id": "GO:0005452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005452", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" }, { "name": "bicarbonate transport", "id": "GO:0015701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015701", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" }, { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" }, { "name": "regulation of cardiac muscle cell action potential", "id": "GO:0098901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098901", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" }, { "name": "pH reduction", "id": "GO:0045851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045851", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKM3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 867, "end_pos": 869, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "72363", "name": "", "equation": "hydrogencarbonate(in) + chloride(out) = hydrogencarbonate(out) + chloride(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72363", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72363" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NKM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" }, { "id": "PF07565", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07565" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Band 3 cytoplasmic", "eco_id": "ECO_0000259", "start_pos": 317, "end_pos": 615, "start_aa": "His", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NKM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM3" }, { "id": "PF00955", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00955" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bicarbonate transporter-like transmembrane", "eco_id": "ECO_0000259", "start_pos": 679, "end_pos": 850, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 122, 667 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 438, "end_pos": 440 }, { "start_pos": 867, "end_pos": 869 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", 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"A0ABI0NM26-1", "uniprot_ac": "A0ABI0NM26", "uniprot_id": "A0ABI0NM26_BOVIN", "mass": { "chemical_mass": 30982.0, "monoisotopic_mass": 30982.0 }, "refseq": { "ac": "NP_001179211", "name": "inositol monophosphatase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179211" }, "gene_names": [ { "name": "IMPA2", "type": "recommended", "evidence": [ { "id": "A0ABI0NM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26" } ] }, { "name": "IMPA2", "type": "synonym", "evidence": [ { "id": "NP_001179211", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179211" } ] } ], "protein_names": [ { "name": "Inositol-1-monophosphatase", "type": "recommended", "evidence": [ { "id": "A0ABI0NM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.25", "type": "synonym", "evidence": [ { "id": "A0ABI0NM26", "database": "UniProtKB", "url": 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"Protein Classification" ] }, { "id": "IPR033942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511124", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QTIHYGR", "url": "https://omabrowser.org/oma/group/QTIHYGR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BPR2", "url": "https://www.orthodb.org/?gene=E1BPR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20854:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20854:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00459", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00459", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1855183", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855183", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179211", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179211", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16689", "url": "https://www.rhea-db.org/rhea/16689", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "24056", "url": "https://www.rhea-db.org/rhea/24056", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29315", "url": "https://www.rhea-db.org/rhea/29315", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "35603", "url": "https://www.rhea-db.org/rhea/35603", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "82131", "url": "https://www.rhea-db.org/rhea/82131", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NM26", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM26-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BPR2", "url": "https://www.uniprot.org/uniprotkb/E1BPR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BPR2-1", "url": "https://www.uniprot.org/uniprotkb/E1BPR2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKASGEDGEAPAGGPWEECFEAAVQLALRAGQIIRKALSEEKRVSTKTSAADLVTETDHVVEALILQELQTRFPSHRFIAEEAAAAGAKCVLTPSPTWIVDPIDGTCNFVHRFPTVAVSIGFAVNQELEFGVIYHCTEERLYTGRRGQGAFCNGQRLRVSGETDLSKALVLTEIGPRRDPATLKLFLSNMERLLHAGAHGVRVIGSSTLALCHLAAGTADAYYQFGLHCWDLAAATVIIREAGGVVMDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDER", "length": 288, "header": "tr|A0ABI0NM26-1|A0ABI0NM26_BOVIN Isoform 1 of Inositol-1-monophosphatase OS=Bos taurus OX=9913 GN=IMPA2 PE=3 SV=1 CANONICAL=A0ABI0NM26-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NM26-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26/entry#A0ABI0NM26-1", "sequence": { "sequence": "MKASGEDGEAPAGGPWEECFEAAVQLALRAGQIIRKALSEEKRVSTKTSAADLVTETDHVVEALILQELQTRFPSHRFIAEEAAAAGAKCVLTPSPTWIVDPIDGTCNFVHRFPTVAVSIGFAVNQELEFGVIYHCTEERLYTGRRGQGAFCNGQRLRVSGETDLSKALVLTEIGPRRDPATLKLFLSNMERLLHAGAHGVRVIGSSTLALCHLAAGTADAYYQFGLHCWDLAAATVIIREAGGVVMDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDER", "length": 288, "header": "tr|A0ABI0NM26-1|A0ABI0NM26_BOVIN Isoform 1 of Inositol-1-monophosphatase OS=Bos taurus OX=9913 GN=IMPA2 PE=3 SV=1 CANONICAL=A0ABI0NM26-1" }, "locus": { "chromosome": "24", "start_pos": 42770389, "end_pos": 42749515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145943.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145943.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106423.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106423.1" } ] } }, { "isoform_ac": "E1BPR2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26/entry#E1BPR2-1", "sequence": { "sequence": "SRAAEPKKPAEGSALFALSLCSALPFLGAPRLGSSGHVRRQVRGAGGGRAQGWLGPPSLDKAQGCVPAIRTEGGRRRSPVPAAVPFLKIIRKALSEEKRVSTKTSAADLVTETDHVVEALILQELQTRFPSHRFIAEEAAAAGAKCVLTPSPTWIVDPIDGTCNFVHRFPTVAVSIGFAVNQELEFGVIYHCTEERLYTGRRGQGAFCNGQRLRVSGETDLSKALVLTEIGPRRDPATLKLFLSNMERLLHAGAHGVRVIGSSTLALCHLAAGTADAYYQFGLHCWDLAAATVIIREAGGVVMDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDER", "length": 344, "header": "tr|E1BPR2-1|A0ABI0NM26_BOVIN Computationally mapped isoform of Inositol-1-monophosphatase OS=Bos taurus OX=9913 GN=IMPA2 PE=3 SV=4 CANONICAL=A0ABI0NM26-1" }, "locus": { "chromosome": "24", "start_pos": 42770389, "end_pos": 42750023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061313.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061313.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053379.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053379.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:511124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511124", "resource": "KEGG Pathway" }, { "id": "R-BTA-1855183", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855183", "resource": "Reactome", "description": "Synthesis of IP2, IP, and Ins in the cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "O14732-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "IMPA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK", "length": 288 }, "evidence": [ { "id": "A0ABI0NM26", "url": "https://omabrowser.org/oma/group/A0ABI0NM26/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CIN7-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "Impa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPNSEEEEELVQGVGPWDECFEVAVQLALRAGQIIRKALTEEKHVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKAHGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDEK", "length": 290 }, "evidence": [ { "id": "A0ABI0NM26", "url": "https://omabrowser.org/oma/group/A0ABI0NM26/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91UZ5-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "Impa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPSSEEEGELVQGVGPWDECFEVAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKAHGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDEK", "length": 290 }, "evidence": [ { "id": "A0ABI0NM26", "url": "https://omabrowser.org/oma/group/A0ABI0NM26/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "inositol metabolic process", "id": "GO:0006020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM26", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM26", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26" } ], "pmid": "" }, { "name": "response to lithium ion", "id": "GO:0010226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010226", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM26", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26" } ], "pmid": "" }, { "name": "inositol biosynthetic process", "id": "GO:0006021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006021", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM26", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM26", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM26", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM26", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM26", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26" } ], "pmid": "" }, { "name": "inositol monophosphate 1-phosphatase activity", "id": "GO:0008934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008934", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM26", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26" } ], "pmid": "" }, { "name": "inositol monophosphate phosphatase activity", "id": "GO:0052834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052834", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM26", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16689", "name": "", "equation": "D-glucose 6-phosphate + H2O = D-glucose + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q148G2-1", "Q29RU6-1", "P20456-1", "A0ABI0NM26-1", "F1MSR0-1" ], "evidence": [ { "id": "16689", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16689" } ] }, { "id": "24056", "name": "", "equation": "a myo-inositol phosphate + H2O = myo-inositol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P20456-1", "A0ABI0NM26-1" ], "evidence": [ { "id": "24056", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24056" } ] }, { "id": "29315", "name": "", "equation": "alpha-D-galactose 1-phosphate + H2O = D-galactose + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P20456-1", "A0ABI0NM26-1" ], "evidence": [ { "id": "29315", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29315" } ] }, { "id": "35603", "name": "", "equation": "beta-D-fructose 1-phosphate + H2O = D-fructose + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A3KMX8-1", "P20456-1", "A0ABI0NM26-1", "A0ABI0NJE0-1" ], "evidence": [ { "id": "35603", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35603" } ] }, { "id": "82131", "name": "", "equation": "scyllo-inositol 1-phosphate + H2O = scyllo-inositol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P20456-1", "A0ABI0NM26-1" ], "evidence": [ { "id": "82131", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/82131" } ] }, { "id": "R-BTA-1855154", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-870330" ], "output_participant_list": [], "enzyme_list": [ "P20456-1", "A0ABI0NM26-1" ], "evidence": [ { "id": "R-BTA-1855154", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855154" } ] }, { "id": "R-BTA-1855210", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P20456-1", "A0ABI0NM26-1" ], "evidence": [ { "id": "R-BTA-1855210", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855210" } ] }, { "id": "R-BTA-1855211", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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"url": "https://www.uniprot.org/uniprotkb/E1BNY3", "locus": { "chromosome": "10", "start_pos": 62638620, "end_pos": 62696011, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016800", "url": "https://www.ensembl.org/id/ENSBTAG00000016800" } ] } } ], "crossref": [ { "id": "E1BNY3", "url": "https://alphafold.ebi.ac.uk/entry/E1BNY3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016800", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016800", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "518458", "url": "https://www.ncbi.nlm.nih.gov/gene/518458", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:518458", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518458", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EAYNHAX", "url": "https://omabrowser.org/oma/group/EAYNHAX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M5K3", "url": "https://www.orthodb.org/?gene=A0A3Q1M5K3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MDS6", "url": "https://www.orthodb.org/?gene=A0A3Q1MDS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MLI3", "url": "https://www.orthodb.org/?gene=A0A3Q1MLI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BNY3", "url": "https://www.orthodb.org/?gene=E1BNY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178062", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178062", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5K3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDS6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MLI3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MLI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMS5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNY3-1", "url": "https://www.uniprot.org/uniprotkb/E1BNY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFFLLCAYMLLLLISQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEIPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYKLNTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRIRYRLTAIAVDHSAGPHQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDRKVISLQLDKDHHALYVAFSSCVIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGACGRVSPAMLAGGFEQDTEYGNTAHLGDCHEILPTSTTPDYKIFGGPTSDMEVSSSSVTTMASIPEITPKVIDTWRPKLTSSRKFVVQDDPNTSDFTDPLSGIPKGVRWEVQSGEANQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQTLMLDPVGPMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLSSPNGVLLSRQPSMNRGGYVPTPAGPKVDYIQGAPVSAHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY", "length": 1073, "header": "tr|E1BNY3-1|E1BNY3_BOVIN Isoform 1 of Semaphorin-6D OS=Bos taurus OX=9913 GN=SEMA6D PE=3 SV=2 CANONICAL=E1BNY3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M5K3-1", "url": "https://www.uniprot.org/uniprotkb/E1BNY3/entry#A0A3Q1M5K3-1", "sequence": { "sequence": "MRFFLLCAYMLLLLISQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEIPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYKLNTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRIRYRLTAIAVDHSAGPHQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDRKVISLQLDKDHHALYVAFSSCVIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGACGRVSPAMLAGGFEQDTEYGNTAHLGDCHDMEVSSSSVTTMASIPEITPKVIDTWRPKLTSSRKFVVQDDPNTSDFTDPLSGIPKGVRWEVQSGEANQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQTLMLDPVGPMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLSSPNGVLLSRQPSMNRGGYVPTPAGPKVDYIQGAPVSAHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY", "length": 1054, "header": "tr|A0A3Q1M5K3-1|E1BNY3_BOVIN Computationally mapped isoform of Semaphorin-6D OS=Bos taurus OX=9913 GN=SEMA6D PE=3 SV=1 CANONICAL=E1BNY3-1" }, "locus": { "chromosome": "10", "start_pos": 62653798, "end_pos": 62641057, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085838.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085838.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065582.1", "url": "https://www.ensembl.org/id/ENSBTAP00000065582.1" } ] } }, { "isoform_ac": "A0A3Q1MDS6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNY3/entry#A0A3Q1MDS6-1", "sequence": { "sequence": "MRFFLLCAYMLLLLISQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEIPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYKLNTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRIRYRLTAIAVDHSAGPHQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDRKVISLQLDKDHHALYVAFSSCVIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGACGRVSPAMLLLTEDLFAFHNHSAGGFEQDTEYGNTAHLGDCHGVRWEVQSGEANQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQTLMLDPVGPMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLSSPNGVLLSRQPSMNRGGYVPTPAGPKVDYIQGAPVSAHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY", "length": 1011, "header": "tr|A0A3Q1MDS6-1|E1BNY3_BOVIN Computationally mapped isoform of Semaphorin-6D OS=Bos taurus OX=9913 GN=SEMA6D PE=3 SV=2 CANONICAL=E1BNY3-1" }, "locus": { "chromosome": "10", "start_pos": 62653798, "end_pos": 62641057, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083251.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083251.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072290.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072290.2" } ] } }, { "isoform_ac": "A0A3Q1MLI3-1", "url": "https://www.uniprot.org/uniprotkb/E1BNY3/entry#A0A3Q1MLI3-1", "sequence": { "sequence": "MRFFLLCAYMLLLLISQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEIPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYKLNTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRIRYRLTAIAVDHSAGPHQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDRKVISLQLDKDHHALYVAFSSCVIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGACGRVSPAMLAGGFEQDTEYGNTAHLGDCHEILPTSTTPDYKIFGGPTSGVRWEVQSGEANQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQTLMLDPVGPMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLSSPNGVLLSRQPSMNRGGYVPTPAGPKVDYIQGAPVSAHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY", "length": 1017, "header": "tr|A0A3Q1MLI3-1|E1BNY3_BOVIN Computationally mapped isoform of Semaphorin-6D OS=Bos taurus OX=9913 GN=SEMA6D PE=3 SV=1 CANONICAL=E1BNY3-1" }, "locus": { "chromosome": "10", "start_pos": 62653798, "end_pos": 62641057, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076742.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076742.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070146.1", "url": "https://www.ensembl.org/id/ENSBTAP00000070146.1" } ] } }, { "isoform_ac": "A0A3Q1MMS5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNY3/entry#A0A3Q1MMS5-1", "sequence": { "sequence": "MRFFLLCAYMLLLLISQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEIPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYKLNTLEYDGEEISGLARCPFDARQTNVALFAEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRIRYRLTAIAVDHSAGPHQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDRKVISLQLDKDHHALYVAFSSCVIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGACGRVSPAMLAGGFEQDTEYGNTAHLGDCHEILPTSTTPDYKIFGGPTSDMEVSSSSVTTMASIPEITPKVIDTWRPKLTSSRKFVVQDDPNTSDFTDPLSGIPKGVRWEVQSGEANQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQTLMLDPVGPMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLSSPNGVLLSRQPSMNRGGYVPTPAGPKVDYIQGAPVSAHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY", "length": 1033, "header": "tr|A0A3Q1MMS5-1|E1BNY3_BOVIN Computationally mapped isoform of Semaphorin-6D OS=Bos taurus OX=9913 GN=SEMA6D PE=3 SV=1 CANONICAL=E1BNY3-1" }, "locus": { "chromosome": "10", "start_pos": 62653798, "end_pos": 62641057, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078627.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078627.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073130.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073130.2" } ] } }, { "isoform_ac": "E1BNY3-1", "url": "https://www.uniprot.org/uniprotkb/E1BNY3/entry#E1BNY3-1", "sequence": { "sequence": "MRFFLLCAYMLLLLISQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEIPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYKLNTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRIRYRLTAIAVDHSAGPHQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDRKVISLQLDKDHHALYVAFSSCVIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGACGRVSPAMLAGGFEQDTEYGNTAHLGDCHEILPTSTTPDYKIFGGPTSDMEVSSSSVTTMASIPEITPKVIDTWRPKLTSSRKFVVQDDPNTSDFTDPLSGIPKGVRWEVQSGEANQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQTLMLDPVGPMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLSSPNGVLLSRQPSMNRGGYVPTPAGPKVDYIQGAPVSAHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY", "length": 1073, "header": "tr|E1BNY3-1|E1BNY3_BOVIN Isoform 1 of Semaphorin-6D OS=Bos taurus OX=9913 GN=SEMA6D PE=3 SV=2 CANONICAL=E1BNY3-1" }, "locus": { "chromosome": "10", "start_pos": 62653798, "end_pos": 62641057, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022349.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022349.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022349.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022349.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1003, "start_aa": "Thr", "end_pos": 1003, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1003", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:518458", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518458", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZC4-1", "protein_name": "Semaphorin-6D", "gene_name": "Sema6d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFFLLWFCVLFLLVSRLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNDIPQTEVIPSKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVIGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDDTLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIEVDRSAGPYQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNPAKCSAESEEDRKVVSLQLDRDHHALYVAFSSCVVRIPLSRCERYGSCKKSCIASRDPYCGWLSQGVCERVTLGMLAGGYEQDTEYGNTAHLGDCHESLPTSTTPDYKIFGGPTSDMEVPSSSVTTVASSPEITSKVIDTWRPKLTSSRKFVVQDDPNTSDFTDTISGVRWEVQSGDSNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNTDPKSMAMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSDKAHGHGASRKEHPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNVDHPLTKSSSKREHRRSVDSRNTLNDLLKHLNDPNSNAKAIMGEIHMAHQTLMLDPVGPMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAVPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY", "length": 1069 }, "evidence": [ { "id": "E1BNY3", "url": "https://omabrowser.org/oma/group/E1BNY3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A1D5PMF8-1", "protein_name": "Semaphorin-6D", "gene_name": "SEMA6D", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLPLLCASVMLMSLSQCRAVSFPEDEDPINIVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEVPKSEVTPSRKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIEINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPSIIEEPWFTKTRVRYRLTAIAVDHAAGPHQNYTVIFVGSEAGVVLKILAKTRPFSLNDSVLLEEIEAYNHAKCNAESEEDRRVISLQLDRDHHALFVAFSSCVVRIPLSRCERHGSCKKACIASRDPYCGWLDHEECGRVTPGMPFSLFVSYNHSTGGYVQDVEYGNTAQLGDCHEILPTTATPDYKIFGDPTSDMKFSSASITTMASIPVISPRVIGSWKPKVTGSRKFVVQDDPNTSDYSDPLSGVPKGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDVFVRKSRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYTNLLTSRKELPPNGDMKSMMMDHRGQPPELAALPTPESTPVLQQKTLQAMKSQSDKAHGNLNASRKETPLKSPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKADKKMQHIDHPLTKPSSKRDHRRSVDSRNTLNDFLKHLNETTSNPKAIMGDIQVAHQTLMLDPMGNMSEIPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPAVPMTSLERQRGYHKNSSQRHSISALPKNLNSPNGVLLSRQPSINRGGYVTPTAGTKMDYMQGTPVSVHLQPSLSRQSSYTSNGTLPRTGIKRTPSLKPDVPPKPSFVPQTTSVRPLNKYSY", "length": 1088 }, "evidence": [ { "id": "E1BNY3", "url": "https://omabrowser.org/oma/group/E1BNY3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A287BLQ6-1", "protein_name": "Semaphorin-6D", "gene_name": "SEMA6D", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRFFLLCAYMLLLMIPQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEIPKTEVVPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLNTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRIRYRLTAIAVDHSAGPHQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDRKVLSLQLDKDHHALYVAFSSCVIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGACGRVMPGMLAGGFEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSDMEVSSSSVTTMASIPEITPKVIDTWRPKLTSSRKFVVQDDPNTSDFTDPLSGVRWEVQSGDSNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGETKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSDKVHGHGASRKETSQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQTLMLDPVGPMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLSSPNGVLLSRQPSVNRGGYMATPTGAKVDYVQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY", "length": 1069 }, "evidence": [ { "id": "E1BNY3", "url": "https://omabrowser.org/oma/group/E1BNY3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q76KF0-1", "protein_name": "Semaphorin-6D", "gene_name": "Sema6d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGFLLLWFCVLFLLVSRLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEIPQTEVIPSKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLRTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDDTLAFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIEVDRSAGPYQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNPAKCSAESEEDRKVVSLQLDKDHHALYVAFSSCVVRIPLSRCERYGSCKKSCIASRDPYCGWLSQGVCERVTLGMLPGGYEQDTEYGNTAHLGDCHESLPPSTTPDYKIFGGPTSDMEVSSSSVTTVASSPEITSKVIDTWRPKLTSSRKFVVQDDPNTSDFTDTISGIPKGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNTDTKSMAVDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHSHGASRKEHPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQSMDHPLTKSSSKREHRRSVDSRNTLNDLLKHLNDPNSNPKAILGEIHMAHQTLMLDPVGPMAEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAVPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY", "length": 1073 }, "evidence": [ { "id": "E1BNY3", "url": "https://omabrowser.org/oma/group/E1BNY3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NFY4-1", "protein_name": "Semaphorin-6D", "gene_name": "SEMA6D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSDMEVSSSSVTTMASIPEITPKVIDTWRPKLTSSRKFVVQDDPNTSDFTDPLSGIPKGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRPLNKYTY", "length": 1073 }, "evidence": [ { "id": "E1BNY3", "url": "https://omabrowser.org/oma/group/E1BNY3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" } ], "pmid": "" }, { "name": "T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell", "id": "GO:0002291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002291", "evidence": [ { "database": "UniProtKB", "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499", "evidence": [ { "database": "UniProtKB", "id": "E1BNY3", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1034, "end_pos": 1036, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 832, "end_pos": 834, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" }, { "start_pos": 967, "end_pos": 969, "annotation": "n_glycosylation_sequon" }, { "start_pos": 980, "end_pos": 982, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNY3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1073, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNY3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNY3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY3" }, { "id": "PS51004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sema", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 512, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1003 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1034, "end_pos": 1036 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 832, "end_pos": 834 }, { "start_pos": 838, "end_pos": 840 }, { "start_pos": 967, "end_pos": 969 }, { "start_pos": 980, "end_pos": 982 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NKG0-1", "uniprot_ac": "A0ABI0NKG0", "uniprot_id": "A0ABI0NKG0_BOVIN", "mass": { "chemical_mass": 101419.0, "monoisotopic_mass": 101419.0 }, "refseq": {}, "gene_names": [ { "name": "ERMP1", "type": "recommended", "evidence": [ { "id": "A0ABI0NKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0" } ] } ], "protein_names": [ { "name": "Endoplasmic reticulum metallopeptidase 1", "type": "recommended", "evidence": [ { "id": "A0ABI0NKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0/entry#names_and_taxonomy" } ] }, { "name": "Felix-ina", "type": "synonym", "evidence": [ { "id": "A0ABI0NKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures.", "evidence": [ { "database": "UniProtKB", "id": "F1MI95", "url": "https://www.uniprot.org/uniprotkb/F1MI95#function" }, { "database": "UniProtKB", "id": "ARBA00054905", "url": "https://www.uniprot.org/uniprotkb/ARBA00054905#function" }, { "database": "UniProtKB", "id": "A0A3Q1M5Z7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5Z7#function" }, { "database": "UniProtKB", "id": "A0AAA9S679", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S679#function" }, { "database": "UniProtKB", "id": "A0AAA9SEL5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEL5#function" }, { "database": "UniProtKB", "id": "A0AAA9SJ16", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ16#function" }, { "database": "UniProtKB", "id": "A0ABI0NKG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0#function" }, { "database": "UniProtKB", "id": "A0ABI0NTV4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTV4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ERMP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0", "locus": { "chromosome": "8", "start_pos": 38943172, "end_pos": 38886773, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015607", "url": "https://www.ensembl.org/id/ENSBTAG00000015607" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015607", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015607", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03875", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03875", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "541094", "url": "https://www.ncbi.nlm.nih.gov/gene/541094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053973", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053973", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541094", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541094", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR12147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12147:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12147:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1M5Z7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S679", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S679", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S679-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S679-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SEL5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SEL5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ16", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ16-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKG0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTV4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTV4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MI95", "url": "https://www.uniprot.org/uniprotkb/F1MI95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MI95-1", "url": "https://www.uniprot.org/uniprotkb/F1MI95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSRWEQNEGVSTRGRLTGHPPPPHPGPSPSGTLEQESASAGLRLDFHEAPSVPQSNRDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEAQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLVRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKYLATSDMLASSSKYQHGNMVFFDVLGLFVIAYPSRVGSIINYMVVMAVVLYLGRKLLHPKYKTATYTKDFFCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTAAVAKIIFIHTLAKRFYYVNASGQYLGEVFFDVSLFVHCGFLTALTYRGLCSAFISAVWVAFPLLTKLCVQKDLKQHGAGGKYIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTIILSSYFRESPALPCLLLFPGTLQGRGGRNGAEWITSTLLEQAPGRALPFVWCQHSPVLWFFSLQFLRINFIYLAKSTKRTMLSLTLVCTVTFLLVCSGTFFPYSSSSASPKPKRVFLQHTTRTFHDLDGNVAKRDSGVWINGFDYTGMSHITPHIPEINDTVRADCEENAPLCGFPWYLPVHFLIRKNWYLPAPEVSPREPAHFRLVSKEQTPWDSIKLTFEATGPSHMSFYVRTHKGATLSQWSLGNGTPVTSKGGDYFVFYSHGLQASTWHFWIEVQVLEEQPEGMVTVAIAAHYFSGEDKRSSQLDALREKFPDWTFPSAWVCTYNLFVF", "length": 910, "header": "tr|A0ABI0NKG0-1|A0ABI0NKG0_BOVIN Isoform 1 of Endoplasmic reticulum metallopeptidase 1 OS=Bos taurus OX=9913 GN=ERMP1 PE=3 SV=1 CANONICAL=A0ABI0NKG0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M5Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0/entry#A0A3Q1M5Z7-1", "sequence": { "sequence": "MAMEWASESGAVRRHRIGGERRDGPAAAQQPEREALAPEPLADACGGGARTRKRSGEGSGGGARRGTGTGLSEARAALGLALYLLALRALVQLSLRQLVLRGAAVGHQGEFDAHQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEAQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLVRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAAATYTKDFFCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTAAVAKIIFIHTLAKRFYYVNASGQYLGEVFFDVSLFVHCGFLTALTYRGLCSAFISAVWVAFPLLTKLCVQKDLKQHGAGGKYIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTIILSSYFINFIYLAKSTKRTMLSLTLVCTVTFLLVCSGTFFPYSSSSASPKPKRVFLQHTTRTFHDLDGNVAKRDSGVWINGFDYTGMSHITPHIPEINDTVRADCEENAPLCGFPWYLPVHFLIRKNWYLPAPEVSPREPAHFRLVSKEQTPWDSIKLTFEATGPSHMSFYVRTHKGATLSQWSLGNGTPVTSKGGDYFVFYSHGLQASTWHFWIEVQVLEEQPEGMVTVAIAAHYFSGEDKRSSQLDALREKFPDWTFPSAWVCTYNLFVF", "length": 837, "header": "tr|A0A3Q1M5Z7-1|A0ABI0NKG0_BOVIN Computationally mapped isoform of Endoplasmic reticulum metallopeptidase 1 OS=Bos taurus OX=9913 GN=ERMP1 PE=3 SV=1 CANONICAL=A0ABI0NKG0-1" }, "locus": { "chromosome": "8", "start_pos": 38942168, "end_pos": 38886972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066545.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066545.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065360.1", "url": "https://www.ensembl.org/id/ENSBTAP00000065360.1" } ] } }, { "isoform_ac": "A0AAA9S679-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0/entry#A0AAA9S679-1", "sequence": { "sequence": "MEWASESGAVRRHRIGGERRDGPAAAQQPEREALAPEPLADACGGGARTRKRSGEGSGGGARRGTGTGLSEARAALGLALYLLALRALVQLSLRQLVLRGAAVGHQGEFDAHQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEAQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKYLATSDMLASSSKYQHGNMVFFDVLGLFVIAYPSRVGSIINYMVVMAVVLYLGRKLLHPKYKTATYTKDFFCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTAAVAKIIFIHTLAKRFYYVINFIYLAKSTKRTMLSLTLVCTVTFLLVCSGTFFPYSSSSASPKPKRVFLQHTTRTFHDLDGNVAKRDSGVWINGFDYTGMSHITPHIPEINDTVRADCEENAPLCGFPWYLPVHFLIRKNWYLPAPEVSPREPAHFRLVSKEQTPWDSIKLTFEATGPSHMSFYVRTHKGATLSQWSLGNGTPVTSKGGDYFVFYSHGLQASTWHFWIEVQVLEEQPEGMVTVAIAAHYFSGEDKRSSQLDALREKFPDWTFPSAWVCTYNLFVF", "length": 706, "header": "tr|A0AAA9S679-1|A0ABI0NKG0_BOVIN Computationally mapped isoform of Endoplasmic reticulum metallopeptidase 1 OS=Bos taurus OX=9913 GN=ERMP1 PE=3 SV=1 CANONICAL=A0ABI0NKG0-1" }, "locus": { "chromosome": "8", "start_pos": 38942168, "end_pos": 38886978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090279.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090279.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080714.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080714.1" } ] } }, { "isoform_ac": "A0AAA9SEL5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0/entry#A0AAA9SEL5-1", "sequence": { "sequence": "MEWASESGAVRRHRIGGERRDGPAAAQQPEREALAPEPLADACGGGARTRKRSGEGSGGGARRGTGTGLSEARAALGLALYLLALRALVQLSLRQLVLRGAAVGHQGEFDAHQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEAQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLVRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKYLATSDMLASSSKYQHGNMVFFDVLGLFVIAYPSRVGSIINYMVVMAVVLYLGRKLLHPKYKTATYTKDFFCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTAAVAKIIFIHTLAKRFYYVINFIYLAKSTKRTMLSLTLVCTVTFLLVCSGTFFPYSSSSASPKPKRVFLQHTTRTFHDLDGNVAKRDSGVWINGFDYTGMSHITPHIPEINDTVRADCEENAPLCGFPWYLPVHFLIRKNWYLPAPEVSPREPAHFRLVSKEQTPWDSIKLTFEATGPSHMSFYVRTHKGATLSQWSLGNGTPVTSKGGDYFVFYSHGLQASTWHFWIEVQVLEEQPEGMVTVAIAAHYFSGEDKRSSQLDALREKFPDWTFPSAWVCTYNLFVF", "length": 784, "header": "tr|A0AAA9SEL5-1|A0ABI0NKG0_BOVIN Computationally mapped isoform of Endoplasmic reticulum metallopeptidase 1 OS=Bos taurus OX=9913 GN=ERMP1 PE=3 SV=1 CANONICAL=A0ABI0NKG0-1" }, "locus": { "chromosome": "8", "start_pos": 38942168, "end_pos": 38886978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099055.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099055.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082051.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082051.1" } ] } }, { "isoform_ac": "A0AAA9SJ16-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0/entry#A0AAA9SJ16-1", "sequence": { "sequence": "MEWASESGAVRRHRIGGERRDGPAAAQQPEREALAPEPLADACGGGARTRKRSGEGSGGGARRGTGTGLSEARAALGLALYLLALRALVQLSLRQLVLRGAAVGHQGEFDAHQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEAQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLVRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGDNILAVLKYLATSDMLASSSKYQHGNMVFFDVLGLFVIAYPSRVGSIINYMVVMAVVLYLGRKLLHPKYKTATYTKDFFCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTAAVAKIIFIHTLAKRFYYVNASGQYLGEVFFDVSLFVHCGFLTALTYRGLCSAFISAVWVAFPLLTKLCVQKDLKQHGAGGKYIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTIILSSYFINFIYLAKSTKRTMLSLTLVCTVTFLLVCSGTFFPYSSSSASPKPKRVFLQHTTRTFHDLDGNVAKRDSGVWINGFDYTGMSHITPHIPEINDTVRADCEENAPLCGFPWYLPVHFLIRKNWYLPAPEVSPREPAHFRLVSKEQTPWDSIKLTFEATGPSHMSFYVRTHKGATLSQWSLGNGTPVTSKGGDYFVFYSHGLQASTWHFWIEVQVLEEQPEGMVTVAIAAHYFSGEDKRSSQLDALREKFPDWTFPSAWVCTYNLFVF", "length": 875, "header": "tr|A0AAA9SJ16-1|A0ABI0NKG0_BOVIN Computationally mapped isoform of Endoplasmic reticulum metallopeptidase 1 OS=Bos taurus OX=9913 GN=ERMP1 PE=3 SV=1 CANONICAL=A0ABI0NKG0-1" }, "locus": { "chromosome": "8", "start_pos": 38942168, "end_pos": 38886978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093259.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093259.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082556.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082556.1" } ] } }, { "isoform_ac": "A0ABI0NKG0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0/entry#A0ABI0NKG0-1", "sequence": { "sequence": "MRSRWEQNEGVSTRGRLTGHPPPPHPGPSPSGTLEQESASAGLRLDFHEAPSVPQSNRDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEAQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLVRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKYLATSDMLASSSKYQHGNMVFFDVLGLFVIAYPSRVGSIINYMVVMAVVLYLGRKLLHPKYKTATYTKDFFCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTAAVAKIIFIHTLAKRFYYVNASGQYLGEVFFDVSLFVHCGFLTALTYRGLCSAFISAVWVAFPLLTKLCVQKDLKQHGAGGKYIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTIILSSYFRESPALPCLLLFPGTLQGRGGRNGAEWITSTLLEQAPGRALPFVWCQHSPVLWFFSLQFLRINFIYLAKSTKRTMLSLTLVCTVTFLLVCSGTFFPYSSSSASPKPKRVFLQHTTRTFHDLDGNVAKRDSGVWINGFDYTGMSHITPHIPEINDTVRADCEENAPLCGFPWYLPVHFLIRKNWYLPAPEVSPREPAHFRLVSKEQTPWDSIKLTFEATGPSHMSFYVRTHKGATLSQWSLGNGTPVTSKGGDYFVFYSHGLQASTWHFWIEVQVLEEQPEGMVTVAIAAHYFSGEDKRSSQLDALREKFPDWTFPSAWVCTYNLFVF", "length": 910, "header": "tr|A0ABI0NKG0-1|A0ABI0NKG0_BOVIN Isoform 1 of Endoplasmic reticulum metallopeptidase 1 OS=Bos taurus OX=9913 GN=ERMP1 PE=3 SV=1 CANONICAL=A0ABI0NKG0-1" }, "locus": { "chromosome": "8", "start_pos": 38942168, "end_pos": 38819154, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138289.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138289.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105211.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105211.1" } ] } }, { "isoform_ac": "A0ABI0NTV4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0/entry#A0ABI0NTV4-1", "sequence": { "sequence": "MRSRWEQNEGVSTRGRLTGHPPPPHPGPSPSGTLEQESASAGLRLDFHEAPSVPQSNRDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEAQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLVRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKYLATSDMLASSSKYQHGNMVFFDVLGLFVIAYPSRVGSIINYMVVMAVVLYLGRKLLHPKYKTATYTKDFFCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTAAVAKIIFIHTLAKRFYYVNASGQYLGEVFFDVSLFVHCGFLTALTYRGLCSAFISAVWVAFPLLTKLCVQKDLKQHGAGGKYIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTIILSSYFINFIYLAKSTKRTMLSLTLVCTVTFLLVCSGTFFPYSSSSASPKPKRVFLQHTTRTFHDLDGNVAKRDSGVWINGFDYTGMSHITPHIPEINDTVRADCEENAPLCGFPWYLPVHFLIRKNWYLPAPEVSPREPAHFRLVSKEQTPWDSIKLTFEATGPSHMSFYVRTHKGATLSQWSLGNGTPVTSKGGDYFVFYSHGLQASTWHFWIEVQVLEEQPEGMVTVAIAAHYFSGEDKRSSQLDALREKFPDWTFPSAWVCTYNLFVF", "length": 849, "header": "tr|A0ABI0NTV4-1|A0ABI0NTV4_BOVIN Computationally mapped isoform of Endoplasmic reticulum metallopeptidase 1 OS=Bos taurus OX=9913 GN=ERMP1 PE=3 SV=1 CANONICAL=A0ABI0NKG0-1" }, "locus": { "chromosome": "8", "start_pos": 38942168, "end_pos": 38819154, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138296.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138296.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106913.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106913.1" } ] } }, { "isoform_ac": "F1MI95-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0/entry#F1MI95-1", "sequence": { "sequence": "MAMEWASESGAVRRHRIGGERRDGPAAAQQPEREALAPEPLADACGGGARTRKRSGEGSGGGARRGTGTGLSEARAALGLALYLLALRALVQLSLRQLVLRGAAVGHQGEFDAHQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEAQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLVRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKYLATSDMLASSSKYQHGNMVFFDVLGLFVIAYPSRVGSIINYMVVMAVVLYLGRKLLHPKYKTATYTKDFFCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTAAVAKIIFIHTLAKRFYYVNASGQYLGEVFFDVSLFVHCGFLTALTYRGLCSAFISAVWVAFPLLTKLCVQKDLKQHGAGGKYIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTIILSSYFINFIYLAKSTKRTMLSLTLVCTVTFLLVCSGTFFPYSSSSASPKPKRVFLQHTTRTFHDLDGNVAKRDSGVWINGFDYTGMSHITPHIPEINDTVRADCEENAPLCGFPWYLPVHFLIRKNWYLPAPEVSPREPAHFRLVSKEQTPWDSIKLTFEATGPSHMSFYVRTHKGATLSQWSLGNGTPVTSKGGDYFVFYSHGLQASTWHFWIEVQVLEEQPEGMVTVAIAAHYFSGEDKRSSQLDALREKFPDWTFPSAWVCTYNLFVF", "length": 908, "header": "tr|F1MI95-1|A0ABI0NKG0_BOVIN Computationally mapped isoform of Endoplasmic reticulum metallopeptidase 1 OS=Bos taurus OX=9913 GN=ERMP1 PE=3 SV=4 CANONICAL=A0ABI0NKG0-1" }, "locus": { "chromosome": "8", "start_pos": 38942168, "end_pos": 38886972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020731.8", "url": "https://www.ensembl.org/id/ENSBTAT00000020731.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020731.7", "url": "https://www.ensembl.org/id/ENSBTAP00000020731.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:541094", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541094", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0" } ], "pmid": "" }, { "name": "metalloexopeptidase activity", "id": "GO:0008235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008235", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 825, "end_pos": 827, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0" }, { "id": "PF22248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endoplasmic reticulum metallopeptidase 1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 687, "end_pos": 908, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0" }, { "id": "PF22249", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endoplasmic reticulum metallopeptidase 1/1-A TM", "eco_id": "ECO_0000259", "start_pos": 391, "end_pos": 583, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG0" }, { "id": "PF04389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M28", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 323, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 736, "end_pos": 738 }, { "start_pos": 825, "end_pos": 827 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMP1-1", "uniprot_ac": "E1BMP1", "uniprot_id": "E1BMP1_BOVIN", "mass": { "chemical_mass": 100243.0, "monoisotopic_mass": 100243.0 }, "refseq": { "ac": "XP_005214188", "name": "scm-like with four MBT domains protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214188" }, "gene_names": [ { "name": "SFMBT2", "type": "recommended", "evidence": [ { "id": "E1BMP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP1" } ] }, { "name": "SFMBT2", "type": "synonym", "evidence": [ { "id": "XP_005214188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214188" } ] } ], "protein_names": [ { "name": "Scm like with four mbt domains 2", "type": "synonym", "evidence": [ { "id": "E1BMP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP1/entry#names_and_taxonomy" } ] }, { "name": "scm-like with four MBT domains protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005214188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214188" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMP1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SFMBT2", "url": "https://www.uniprot.org/uniprotkb/E1BMP1", "locus": { "chromosome": "13", "start_pos": 16560875, "end_pos": 16387246, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005915", "url": "https://www.ensembl.org/id/ENSBTAG00000005915" } ] } } ], "crossref": [ { "id": "E1BMP1", "url": "https://alphafold.ebi.ac.uk/entry/E1BMP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005915", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005915", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09581", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09581", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20114", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20114", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "528635", "url": "https://www.ncbi.nlm.nih.gov/gene/528635", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047354", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047354", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M8G3", "url": "https://www.orthodb.org/?gene=A0A3Q1M8G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BMP1", "url": "https://www.orthodb.org/?gene=E1BMP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005214188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214188", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LT04", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LT04-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8G3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8G3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMP1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMP1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGSVSISSMQDPSSSPLEKHQSSADRNGDLDSEGSSLEETGFNWGEYLEETGASAAPHTSFKHVEISIQSNFQPGMKLEVANKKNPDTYWVATVITTCGQLLLLRYCGYGEDRRADFWCDVVIADLHPVGWCTQNNKTLMPPDAIKEKYTDWTEFLIRDLTGSRTAPASLLEGPLRGKGPIDLITVDSLIELQDSQNPFQYWIVSVLENAGGRLRLRYVGLEDTESYDQWLFYLDYRLRPVGWCQENKYRMDPPSEIYPLKTDSEWKRALEKSLIDAAKFPLPMEVFKDHADLRSHFFTVGMKLETVNMSHICPASVTKVFNNHFFQVTIDDLRPEPSKLSMLCHADSLGILPVQWCLKNGVNLTPPKGYSGQDFDWADYHKQHGTEEAPPFCFRNTSFSRGFTKNMKLEAVNPRNPGELCVASVIAVKGRLMWLRLEGLQSPAPEFIVDVESMDIFPVGWCEANSYPLTTPHKTASQKKRKIAVVQPEKQSPSTVPVEKIPHDLCLFPHLDATGTVNGKYCCPQLFINHRCFSGPYLNKGRIAELPQSVGPGKCVLVLKEVLSMLINAAYKPGRVLRELQLVEDPHWNFQEETLKAKYRGKTYRAVAKIVRTSDQVADFCRRVCAKLECCPNLFSPVLVSENCPENCSIHTKTKYTYYYGKRRKISKPPIGESRVESGHPKPARRRKRRKSMFVQKKRRSSAVDLAAGSGEESEEEDADAMDDDSGSEETGSEIRDDQTDTSSAEVPSTRPRRAVTLRSSVEAERRAPVERTRRARRAPATPQAEGAPQSPAASQEAAEDVKQEEEERLVLESNPLEWSVTDVVRFIKLTDCAPLAKIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKLCHQIERVKVAFYAQYAN", "length": 890, "header": "tr|E1BMP1-1|E1BMP1_BOVIN Isoform 1 of Scm like with four mbt domains 2 OS=Bos taurus OX=9913 GN=SFMBT2 PE=4 SV=3 CANONICAL=E1BMP1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LT04-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1/entry#A0A3Q1LT04-1", "sequence": { "sequence": "MEGSVSISSMQDPSSSPLEKHQSSADRNGDLDSEEGSSLEETGFNWGEYLEETGASAAPHTSFKHVEISIQSNFQPGMKLEVANKKNPDTYWVATVITTCGQLLLLRYCGYGEDRRADFWCDVVIADLHPVGWCTQNNKTLMPPDEIYPLKTDSEWKRALEKSLIDAAKFPLPMEVFKDHADLRSHFFTVGMKLETVNMSHICPASVTKVFNNHFFQVTIDDLRPEPSKLSMLCHADSLGILPVQWCLKNGVNLTPPKGYSGQDFDWADYHKQHGTEEAPPFCFRNTSFSRGFTKNMKLEAVNPRNPGELCVASVIAVKGRLMWLRLEGLQSPAPEFIVDVESMDIFPVGWCEANSYPLTTPHKTASQKKRKIAVVQPEKQSPSTVPVEKIPHDLCLFPHLDATGTVNGKYCCPQLFINHRCFSGPYLNKGRIAELPQSVGPGKCVLVLKEVLSMLINAAYKPGRVLRELQLVEDPHWNFQEETLKAKYRGKTYRAVAKIVRTSDQVADFCRRVCAKLECCPNLFSPVLVSENCPENCSIHTKTKYTYYYGKRRKISKPPIGESRVESGHPKPARRRKRRKSMFVQKKRRSSAVDLAAGSGEESEEEDADAMDDDSGSEETGSEIRDDQTDTSSAEVPSTRPRRAVTLRSSVEAERRAPVERTRRARRAPATPQAEGAPQSPAASQEAAEDVKQEEEERLVLESNPLEWSVTDVVRFIKLTDCAPLAKIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKLCHQIERVKVAFYAQYAN", "length": 779, "header": "tr|A0A3Q1LT04-1|E1BMP1_BOVIN Computationally mapped isoform of Scm like with four mbt domains 2 OS=Bos taurus OX=9913 GN=SFMBT2 PE=4 SV=1 CANONICAL=E1BMP1-1" }, "locus": { "chromosome": "13", "start_pos": 16559871, "end_pos": 16403760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084353.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084353.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063560.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063560.2" } ] } }, { "isoform_ac": "A0A3Q1M8G3-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1/entry#A0A3Q1M8G3-1", "sequence": { "sequence": "MEGSVSISSMQDPSSSPLEKHQSSADRNGDLDSEEGSSLEETGFNWGEYLEETGASAAPHTSFKHVEISIQSNFQPGMKLEVANKKNPDTYWVATVITTCGQLLLLRYCGYGEDRRADFWCDVVIADLHPVGWCTQNNKTLMPPDAIKEKYTDWTEFLIRDLTGSRTAPASLLEGPLRGKGPIDLITVDSLIELQDSQNPFQYWIVSVLENAGGRLRLRYVGLEDTESYDQWLFYLDYRLRPVGWCQENKYRMDPPSEIYPLKTDSEWKRALEKSLIDAAKFPLPMEVFKDHADLRSHFFTVGMKLETVNMSHICPASVTKVFNNHFFQVTIDDLRPEPSKLSMLCHADSLGILPVQWCLKNGVNLTPPKGYSGQDFDWADYHKQHGTEEAPPFCFRNVLSMLINAAYKPGRVLRELQLVEDPHWNFQEETLKAKYRGKTYRAVAKIVRTSDQVADFCRRVCAKLECCPNLFSPVLVSENCPENCSIHTKTKYTYYYGKRRKISKPPIGESRVESGHPKPARRRKRRKSMFVQKKRRSSAVDLAAGSGEESEEEDADAMDDDSGSEETGSEIRDDQTDTSSAEVPSTRPRRAVTLRSSVEAERRAPVERTRRARRAPATPQAEGAPQSPAASQEAAEDVKQEEEERLVLESNPLEWSVTDVVRFIKLTDCAPLAKIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKLCHQIERVKVAFYAQYAN", "length": 726, "header": "tr|A0A3Q1M8G3-1|E1BMP1_BOVIN Computationally mapped isoform of Scm like with four mbt domains 2 OS=Bos taurus OX=9913 GN=SFMBT2 PE=4 SV=2 CANONICAL=E1BMP1-1" }, "locus": { "chromosome": "13", "start_pos": 16559871, "end_pos": 16403760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067011.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067011.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066733.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066733.2" } ] } }, { "isoform_ac": "E1BMP1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1/entry#E1BMP1-1", "sequence": { "sequence": "MEGSVSISSMQDPSSSPLEKHQSSADRNGDLDSEGSSLEETGFNWGEYLEETGASAAPHTSFKHVEISIQSNFQPGMKLEVANKKNPDTYWVATVITTCGQLLLLRYCGYGEDRRADFWCDVVIADLHPVGWCTQNNKTLMPPDAIKEKYTDWTEFLIRDLTGSRTAPASLLEGPLRGKGPIDLITVDSLIELQDSQNPFQYWIVSVLENAGGRLRLRYVGLEDTESYDQWLFYLDYRLRPVGWCQENKYRMDPPSEIYPLKTDSEWKRALEKSLIDAAKFPLPMEVFKDHADLRSHFFTVGMKLETVNMSHICPASVTKVFNNHFFQVTIDDLRPEPSKLSMLCHADSLGILPVQWCLKNGVNLTPPKGYSGQDFDWADYHKQHGTEEAPPFCFRNTSFSRGFTKNMKLEAVNPRNPGELCVASVIAVKGRLMWLRLEGLQSPAPEFIVDVESMDIFPVGWCEANSYPLTTPHKTASQKKRKIAVVQPEKQSPSTVPVEKIPHDLCLFPHLDATGTVNGKYCCPQLFINHRCFSGPYLNKGRIAELPQSVGPGKCVLVLKEVLSMLINAAYKPGRVLRELQLVEDPHWNFQEETLKAKYRGKTYRAVAKIVRTSDQVADFCRRVCAKLECCPNLFSPVLVSENCPENCSIHTKTKYTYYYGKRRKISKPPIGESRVESGHPKPARRRKRRKSMFVQKKRRSSAVDLAAGSGEESEEEDADAMDDDSGSEETGSEIRDDQTDTSSAEVPSTRPRRAVTLRSSVEAERRAPVERTRRARRAPATPQAEGAPQSPAASQEAAEDVKQEEEERLVLESNPLEWSVTDVVRFIKLTDCAPLAKIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKLCHQIERVKVAFYAQYAN", "length": 890, "header": "tr|E1BMP1-1|E1BMP1_BOVIN Isoform 1 of Scm like with four mbt domains 2 OS=Bos taurus OX=9913 GN=SFMBT2 PE=4 SV=3 CANONICAL=E1BMP1-1" }, "locus": { "chromosome": "13", "start_pos": 16559871, "end_pos": 16403760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007770.8", "url": "https://www.ensembl.org/id/ENSBTAT00000007770.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007770.7", "url": "https://www.ensembl.org/id/ENSBTAP00000007770.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E1BMP1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "E1BMP1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "E1BMP1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BMP1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BMP1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "E1BMP1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "E1BMP1", "url": "https://www.uniprot.org/uniprotkb/E1BMP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMP1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 890, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMP1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMP1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP1" }, { "id": "PS51079", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51079" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MBT", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 143, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 309, "end_pos": 311 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 648, "end_pos": 650 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NJ87-1", "uniprot_ac": "A0ABI0NJ87", "uniprot_id": "A0ABI0NJ87_BOVIN", "mass": { "chemical_mass": 170831.0, "monoisotopic_mass": 170831.0 }, "refseq": {}, "gene_names": [ { "name": "MAP4", "type": "recommended", "evidence": [ { "id": "A0ABI0NJ87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87" } ] } ], "protein_names": [ { "name": "Microtubule associated protein 4", "type": "synonym", "evidence": [ { "id": "A0ABI0NJ87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ87", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MAP4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87", "locus": { "chromosome": "22", "start_pos": 51909155, "end_pos": 51758311, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015839", "url": "https://www.ensembl.org/id/ENSBTAG00000015839" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015839", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015839", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "281295", "url": "https://www.ncbi.nlm.nih.gov/gene/281295", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027324", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027324", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:281295", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281295", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LSK2", "url": "https://www.orthodb.org/?gene=A0A3Q1LSK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M9W4", "url": "https://www.orthodb.org/?gene=A0A3Q1M9W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MYL9", "url": "https://www.orthodb.org/?gene=A0A3Q1MYL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MY44", "url": "https://www.orthodb.org/?gene=G3MY44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11501:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11501:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00418", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00418", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LJL4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSK2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9W4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MP69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MP69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MP69-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MP69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MYL9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MYL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ87", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ87-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MAZ1", "url": "https://www.uniprot.org/uniprotkb/F1MAZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MAZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1MAZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MAZ3", "url": "https://www.uniprot.org/uniprotkb/F1MAZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MAZ3-1", "url": "https://www.uniprot.org/uniprotkb/F1MAZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0J2", "url": "https://www.uniprot.org/uniprotkb/F1N0J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0J2-1", "url": "https://www.uniprot.org/uniprotkb/F1N0J2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY44", "url": "https://www.uniprot.org/uniprotkb/G3MY44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY44-1", "url": "https://www.uniprot.org/uniprotkb/G3MY44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADLSLADALTEPSPEIEEEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGSSESKKKPCSDTSQVEGTPSSQAAVLANGDHGIERNDVTGFPSEFLEEKMAYQGYQNSQNWPENTNFCFEPEHMVNPIQTDPFKMHHDDGLEDSLFFPSGTTNTSAFVEQNDPLKDTYGMLPCDTFAPAAVVPQGWSAEAPNPAHLESFTSPEAVPQPLQPTAEPAEKVEMASGEERAEALEMMMKLQAADMAPSREAEMVLAKDVVPATETGVALAKDMESPTKPDEALVKDVESSIESDMALVKDVVLPVQTEETAVKDAILPTETDVSLDEDLALSTETEVSAAQDILLFKETESIPPVTMDLASAEGTVPPTDQEMTPVKVAASLSEIEAPLDEDIVSSTEIRSAKEIGLSSETEVALSREMGLPPETEAILDKDMAAPPETEVIVPVKDMAPSPGIETTLAKDVAPRQEIEVTLGKDTVSLPATEMALGRNVALPPETEVTLAKDVAQPPETEVNLANNAALAKFSEAEVVPVPVKDMETAQTQEATSEDSQLKSLQDEGQSAVPLMTSPEAVVAMGQKHSLPTDEDSVLEELEQKKPSSQTSELPSETSGTPPTQAKPAYRPSDRRSARPTRPRPSRVPPELLGGSSPWKTLDPGLGPCPLSELGWVSGSSSCGEPGNQRKTIHGDFLEPQRDLGREAWDIESSPMMMKKKKKKPKQKRYSQPRAGGPWDDDNGDETKGYSFATDSQKSAVPPSQPTTVGTEHGLVSRDDLKGVCETDSREAKLVAESFVSDSLSIPSRPLEEAPKTTVNSQPKQRVEAQVKGNKSAPQGQEKKLLQDECILQAAPHLQTPADESQTVRSLSLKGPLTEVSSHKVEIPLEVRPKESCTPIMNREAVGGVSKPSAAKELPASISTVTAGDPLGNSLKEGNDESKMTELQNDKQKEFSEGAEEVKELKKESVPKQRHENSILASEQLQDTVLAQAPGLGNEPFKRMAGDGKSRKGKTSSGKVRASSGKVRAKSEPPFLADSQDSRAVFVPSGRMATGAKSEELGLDSSKQPGTVAALTEAIVMGEPKEMMDPRVASTLQALIPLGNGSGMIQASSARAERGAVATDMGVSNQSKEEKCPWMGHEAAPWIFEKPKKRGSEGKTKKYKNNYSTQPARMERKEEILNPPFVRKDGVTDSTPHQNKESEPTVPLCSHTSDTPTVEADDQKGRNVEANSFEFGALGGNKTNTGRDSPITEMATKMTDVSCQDQIPGAGFVPSVLAEENKTDVAKGHTAVADKPSKRSNDGKSTKTKNSFPEKHTLENKIDATKIHVPMETIGDHRIEGMGYVDENSNITFTCPRTPPGLMKKSVPLEAQEPSACEKPPTSTSQVVKESDSFPGTLTESKQETAPAQIPKLLEVDSYSKEGVPKEQRPEGPSAVMPSMSTGGVASTLTTAIETVNNHSNCLQDKGELAGAMKNEAGRDGEHVIGDSESTPCGASKHSVEETTEPAGGHLLSGVLANEPSLAGEVRRLEACADRSNFPTCPVNKESEQGSAPVSIPHLLGDKAQKPSFCEDQSTEGRDSKGPDNLNKEVDMTLSLPES", "length": 1593, "header": "tr|A0ABI0NJ87-1|A0ABI0NJ87_BOVIN Isoform 1 of Microtubule associated protein 4 OS=Bos taurus OX=9913 GN=MAP4 PE=4 SV=1 CANONICAL=A0ABI0NJ87-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJL4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87/entry#A0A3Q1LJL4-1", "sequence": { "sequence": "MADLSLADALTEPSPEIEEEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGSSESKKKPCSDTSQVEGTPSSQAAVLANGDHGIERNDVTGFPSEFLEEKMAYQGYQNSQNWPENTNFCFEPEHMVNPIQTDPFKMHHDDGLEDSLFFPSGTTNTSAFVEQNDPLKDTYGMLPCDTFAPAAVVPQGWSAEAPNPAHLESFTSPEAVPQPLQPTAEPAEKVEMASGEERAEALEMMMKLQAADMAPSREAEMVLAKDVVPATETGVALAKDMESPTKPDEALVKDVESSIESDMALVKDVVLPVQTEETAVKDAILPTETDVSLDEDLALSTETEVSAAQDILLFKETESIPPVTMDLASAEGTVPPTDQEMTPVKVAASLSEIEAPLDEDIVSSTEIRSAKEIGLSSETEVTLAKDVAQPPETEVNLANNAALAKFSEAEVVPVPVKDMETAQTQEATSEDSQLKSLQDEGQSAVPLMTSPEAVVAMGQKHSLPTDEDSVLEELEQKKPSSQTSELPSETSGVAKPEEGPPTGSVSGNDITAPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQTAPTTLGGSNKKPMSLASGSVPAAPPKRPAAATSRPSTLPSKDTKPKPVAEAKIPEKRVSPSKPASAPAVKPGSKSTQAVPKAPATATLASPGSTSRNLSTPLPKRPTAIKTEGKPAEIKKMATKSAPADLSRPKSTTTSSVKKSTTVPGTAPPAGAPSRARPTATPPRPSGTPPVDKKPTAAKPTSSAPRLGRVAANASAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAAPARKPEPNAVTKAAGPIGNAQKPPTGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGPPAGEELAIPEAAPEAGAPASASGLSGHTTLAGGGDQREAQTLDSQIQETSI", "length": 1013, "header": "tr|A0A3Q1LJL4-1|A0ABI0NJ87_BOVIN Computationally mapped isoform of Microtubule associated protein 4 OS=Bos taurus OX=9913 GN=MAP4 PE=4 SV=2 CANONICAL=A0ABI0NJ87-1" }, "locus": { "chromosome": "22", "start_pos": 51907642, "end_pos": 51815528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073247.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073247.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056739.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056739.2" } ] } }, { "isoform_ac": "A0A3Q1LSK2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87/entry#A0A3Q1LSK2-1", "sequence": { "sequence": "MADLSLADALTEPSPEIEEEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGSSESKKKPCSDTSQVEGTPSSQAAVLANGDHGIERNDVTGFPSEFLEEKMAYQGYQNSQNWPENTNFCFEPEHMVNPIQTDPFKMHHDDGLEDSLFFPSGTTNTSAFVEQNDPLKDTYGMLPCDTFAPAAVVPQGWSAEAPNPAHLESFTSPEAVPQPLQPTAEPAEKVEMASGEERAEALEMMMKLQAADMAPSREAEMVLAKDVVPATETGVALAKDMESPTKPDEALVKDVESSIESDMALVKDVVLPVQTEETAVKDAILPTETDVSLDEDLALSTETEVSAAQDILLFKETESIPPVTMDLASAEGTVPPTDQEMTPVKVAASLSEIEAPLDEDIVSSTEIRSAKEIGLSSETEVALSREMGLPPETEAILDKDMAAPPETEVIVPVKDMAPSPGIETTLAKDVAPRQEIEVTLGKDTVSLPATEMALGRNVALPPETEVTLAKDVAQPPETEVNLANNAALAKFSEAEVVPVPVKDMETAQTQEATSEDSQLKSLQDEGQSAVPLMTSPEAVVAMGQKHSLPTDEDSVLEELEQKKPSSQTSELPSETSGVAKPEEGPPTGSVSGNDITAPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQTAPTTLGGSNKKPMSLASGSVPAAPPKRPAAATSRPSTLPSKDTKPKPVAEAKIPEKRVSPSKPASAPAVKPGSKSTQAVPKAPATATLASPGSTSRNLSTPLPKRPTAIKTEGKPAEIKKMATKSAPADLSRPKSTTTSSVKKSTTVPGTAPPAGAPSRARPTATPPRPSGTPPVDKKPTAAKPTSSAPRLGRVAANASAPDLKNVRSKVGSTENIKHQPGGGRVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGPPAGEELAIPEAAPEAGAPASASGLSGHTTLAGGGDQREAQTLDSQIQETSI", "length": 1060, "header": "tr|A0A3Q1LSK2-1|A0ABI0NJ87_BOVIN Computationally mapped isoform of Microtubule associated protein 4 OS=Bos taurus OX=9913 GN=MAP4 PE=4 SV=2 CANONICAL=A0ABI0NJ87-1" }, "locus": { "chromosome": "22", "start_pos": 51907642, "end_pos": 51815528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082867.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082867.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063355.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063355.2" } ] } }, { "isoform_ac": "A0A3Q1M9W4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87/entry#A0A3Q1M9W4-1", "sequence": { "sequence": "MADLSLADALTEPSPEIEEEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGSSESKKKPCSDTSQVEGFPSEFLEEKMAYQGYQNSQNWPENTNFCFEPEHMVNPIQTDPFKMHHDDGLEDSLFFPSGTTNTSAFVEQNDPLKDTYGMLPCDTFAPAAVVPQGWSAEAPNPAHLESFTSPEAVPQPLQPTAEPAEKVEMASGEERAEALEMMMKLQAADMAPSREAEMVLAKDVVPATETGVALAKDMESPTKPDEALVKDVESSIESDMALVKDVVLPVQTEETAVKDAILPTETDVSLDEDLALSTETEVSAAQDILLFKETESIPPVTMDLASAEGTVPPTDQEMTPVKVAASLSEIEAPLDEDIVSSTEIRSAKEIGLSSETEVALSREMGLPPETEAILDKDMAAPPETEVIVPVKDMAPSPGIETTLAKDVAPRQEIEVTLGKDTVSLPATEMALGRNVALPPETEVTLAKDVAQPPETEVNLANNAALAKFSEAEVVPVPVKDMETAQTQEATSEDSQLKSLQDEGQSAVPLMTSPEAVVAMGQKHSLPTDEDSVLEELEQKKPSSQTSELPSETSGVAKPEEGPPTGSVSGNDITAPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQTAPTTLGGSNKKPMSLASGSVPAAPPKRPAAATSRPSTLPSKDTKPKPVAEAKIPEKRVSPSKPASAPAVKPGSKSTQAVPKAPATATLASPGSTSRNLSTPLPKRPTAIKTEGKPAEIKKMATKSAPADLSRPKSTTTSSVKKSTTVPGTAPPAGAPSRARPTATPPRPSGTPPVDKKPTAAKPTSSAPRLGRVAANASAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAAPARKPEPNAVTKAAGPIGNAQKPPTGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGPPAGEELAIPEAAPEAGAPASASGLSGHTTLAGGGDQREAQTLDSQIQETN", "length": 1074, "header": "tr|A0A3Q1M9W4-1|A0ABI0NJ87_BOVIN Computationally mapped isoform of Microtubule associated protein 4 OS=Bos taurus OX=9913 GN=MAP4 PE=4 SV=3 CANONICAL=A0ABI0NJ87-1" }, "locus": { "chromosome": "22", "start_pos": 51907739, "end_pos": 51815528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073936.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073936.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066985.3", "url": "https://www.ensembl.org/id/ENSBTAP00000066985.3" } ] } }, { "isoform_ac": "A0A3Q1MP69-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87/entry#A0A3Q1MP69-1", "sequence": { "sequence": "MADLSLADALTEPSPEIEEEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGSSESKKKPCSDTSQVEGTPSSQAAVLANGDHGIERNDVTGFPSEFLEEKMAYQGYQNSQNWPENTNFCFEPEHMVNPIQTDPFKMHHDDGLEDSLFFPSGTTNTSAFVEQNDPLKDTYGMLPCDTFAPAAVVPQGWSAEAPNPAHLESFTSPEAVPQPLQPTAEPAEKVEMASGEERAEALEMMMKLQAADMAPSREAEMVLAKDVVPATETGVALAKDMESPTKPDEALVKDVESSIESDMALVKDVVLPVQTEETAVKDAILPTETDVSLDEDLALSTETEVSAAQDILLFKETESIPPVTMDLASAEGTVPPTDQEMTPVKVAASLSEIEAPLDEDIVSSTEIRSAKEIGLSSETEVALSREMGLPPETEAILDKDMAAPPETEVIVPVKDMAPSPGIETTLAKDVAPRQEIEVTLGKDTVSLPATEMALGRNVALPPETEVTLAKDVAQPPETEVNLANNAALAKFSEAEVVPVPVKDMETAQTQEATSEDSQLKSLQDEGQSAVPLMTSPEAVVAMGQKHSLPTDEDSVLEELEQKKPSSQTSELPSETSGVAKPEEGPPTGSVSGNDITAPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQTAPTTLGGSNKKPMSLASGSVPAAPPKRPAAATSRPSTLPSKDTKPKPVAEAKIPEKRVSPSKPASAPAVKPGSKSTQAVPKAPATATLASPGSTSRNLSTPLPKRPTAIKTEGKPAEIKKMATKSAPADLSRPKSTTTSSVKKSTTVPGTAPPAGAPSRARPTATPPRPSGTPPVDKKPTAAKPTSSAPRLGRVAANASAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAAPARKPEPNAVTKAAGPIGNAQKPPTGKVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGPPAGEELAIPEAAPEAGAPASASGLSGHTTLAGGGDQREAQTLDSQIQETSI", "length": 1067, "header": "tr|A0A3Q1MP69-1|A0ABI0NJ87_BOVIN Computationally mapped isoform of Microtubule associated protein 4 OS=Bos taurus OX=9913 GN=MAP4 PE=4 SV=3 CANONICAL=A0ABI0NJ87-1" }, "locus": { "chromosome": "22", "start_pos": 51907642, "end_pos": 51815528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069879.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069879.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071432.3", "url": "https://www.ensembl.org/id/ENSBTAP00000071432.3" } ] } }, { "isoform_ac": "A0A3Q1MYL9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87/entry#A0A3Q1MYL9-1", "sequence": { "sequence": "MADLSLADALTEPSPEIEEEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGSSESKKKPCSDTSQVEGTPSSQAAVLANGDHGIERNDVTGFPSEFLEEKMAYQGYQNSQNWPENTNFCFEPEHMVNPIQTDPFKMHHDDGLEDSLFFPSGTTNTSAFVEQNDPLKDTYGMLPCDTFAPAAVVPQGWSAEAPNPAHLESFTSPEAVPQPLQPTAEPAEKVEMASGEERAEALEMMMKLQAADMAPSREAEMVLAKDVVPATETGVALAKDMESPTKPDEALVKDVESSIESDMALVKDVVLPVQTEETAVKDAILPTETDVSLDEDLALSTETEVSAAQDILLFKETESIPPVTMDLASAEGTVPPTDQEMTPVKVAASLSEIEAPLDEDIVSSTEIRSAKEIGLSSETEVALSREMGLPPETEAILDKDMAAPPETEVIVPVKDMAPSPGIETTLAKDVAPRQEIEVTLGKDTVSLPATEMALGRNVALPPETEVTLAKDVAQPPETEVNLANNAALAKFSEAEVVPVPVKDMETAQTQEATSEDSQLKSLQDEGQSAVPLMTSPEAVVAMGQKHSLPTDEDSVLEELEQKKPSSQTSELPSETSGVAKPEEGPPTGSVSGNDITAPPNKELPPSPEKKTKPVAEAKIPEKRVSPSKPASAPAVKPGSKSTQAVPKAPATATLASPGSTSRNLSTPLPKRPTAIKTEGKPAEIKKMATKSAPADLSRPKSTTTSSVKKSTTVPGTAPPAGAPSRARPTATPPRPSGTPPVDKKPTAAKPTSSAPRLGRVAANASAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAAPARKPEPNAVTKAAGPIGNAQKPPTGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGPPAGEELAIPEAAPEAGAPASASGLSGHTTLAGGGDQREAQTLDSQIQETSI", "length": 1026, "header": "tr|A0A3Q1MYL9-1|A0ABI0NJ87_BOVIN Computationally mapped isoform of Microtubule associated protein 4 OS=Bos taurus OX=9913 GN=MAP4 PE=4 SV=3 CANONICAL=A0ABI0NJ87-1" }, "locus": { "chromosome": "22", "start_pos": 51907642, "end_pos": 51815528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074061.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074061.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061170.3", "url": "https://www.ensembl.org/id/ENSBTAP00000061170.3" } ] } }, { "isoform_ac": "A0ABI0NJ87-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87/entry#A0ABI0NJ87-1", "sequence": { "sequence": "MADLSLADALTEPSPEIEEEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGSSESKKKPCSDTSQVEGTPSSQAAVLANGDHGIERNDVTGFPSEFLEEKMAYQGYQNSQNWPENTNFCFEPEHMVNPIQTDPFKMHHDDGLEDSLFFPSGTTNTSAFVEQNDPLKDTYGMLPCDTFAPAAVVPQGWSAEAPNPAHLESFTSPEAVPQPLQPTAEPAEKVEMASGEERAEALEMMMKLQAADMAPSREAEMVLAKDVVPATETGVALAKDMESPTKPDEALVKDVESSIESDMALVKDVVLPVQTEETAVKDAILPTETDVSLDEDLALSTETEVSAAQDILLFKETESIPPVTMDLASAEGTVPPTDQEMTPVKVAASLSEIEAPLDEDIVSSTEIRSAKEIGLSSETEVALSREMGLPPETEAILDKDMAAPPETEVIVPVKDMAPSPGIETTLAKDVAPRQEIEVTLGKDTVSLPATEMALGRNVALPPETEVTLAKDVAQPPETEVNLANNAALAKFSEAEVVPVPVKDMETAQTQEATSEDSQLKSLQDEGQSAVPLMTSPEAVVAMGQKHSLPTDEDSVLEELEQKKPSSQTSELPSETSGTPPTQAKPAYRPSDRRSARPTRPRPSRVPPELLGGSSPWKTLDPGLGPCPLSELGWVSGSSSCGEPGNQRKTIHGDFLEPQRDLGREAWDIESSPMMMKKKKKKPKQKRYSQPRAGGPWDDDNGDETKGYSFATDSQKSAVPPSQPTTVGTEHGLVSRDDLKGVCETDSREAKLVAESFVSDSLSIPSRPLEEAPKTTVNSQPKQRVEAQVKGNKSAPQGQEKKLLQDECILQAAPHLQTPADESQTVRSLSLKGPLTEVSSHKVEIPLEVRPKESCTPIMNREAVGGVSKPSAAKELPASISTVTAGDPLGNSLKEGNDESKMTELQNDKQKEFSEGAEEVKELKKESVPKQRHENSILASEQLQDTVLAQAPGLGNEPFKRMAGDGKSRKGKTSSGKVRASSGKVRAKSEPPFLADSQDSRAVFVPSGRMATGAKSEELGLDSSKQPGTVAALTEAIVMGEPKEMMDPRVASTLQALIPLGNGSGMIQASSARAERGAVATDMGVSNQSKEEKCPWMGHEAAPWIFEKPKKRGSEGKTKKYKNNYSTQPARMERKEEILNPPFVRKDGVTDSTPHQNKESEPTVPLCSHTSDTPTVEADDQKGRNVEANSFEFGALGGNKTNTGRDSPITEMATKMTDVSCQDQIPGAGFVPSVLAEENKTDVAKGHTAVADKPSKRSNDGKSTKTKNSFPEKHTLENKIDATKIHVPMETIGDHRIEGMGYVDENSNITFTCPRTPPGLMKKSVPLEAQEPSACEKPPTSTSQVVKESDSFPGTLTESKQETAPAQIPKLLEVDSYSKEGVPKEQRPEGPSAVMPSMSTGGVASTLTTAIETVNNHSNCLQDKGELAGAMKNEAGRDGEHVIGDSESTPCGASKHSVEETTEPAGGHLLSGVLANEPSLAGEVRRLEACADRSNFPTCPVNKESEQGSAPVSIPHLLGDKAQKPSFCEDQSTEGRDSKGPDNLNKEVDMTLSLPES", "length": 1593, "header": "tr|A0ABI0NJ87-1|A0ABI0NJ87_BOVIN Isoform 1 of Microtubule associated protein 4 OS=Bos taurus OX=9913 GN=MAP4 PE=4 SV=1 CANONICAL=A0ABI0NJ87-1" }, "locus": { "chromosome": "22", "start_pos": 51873750, "end_pos": 51815528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143717.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143717.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104438.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104438.1" } ] } }, { "isoform_ac": "F1MAZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87/entry#F1MAZ1-1", "sequence": { "sequence": "MADLSLADALTEPSPEIEEEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGSSESKKKPCSDTSQVEGTPSSQAAVLANGDHGIERNDVTGFPSEFLEEKMAYQGYQNSQNWPENTNFCFEPEHMVNPIQTDPFKMHHDDGLEDSLFFPSGTTNTSAFVEQNDPLKDTYGMLPCDTFAPAAVVPQGWSAEAPNPAHLESFTSPEAVPQPLQPTAEPAEKVEMASGEERAEALEMMMKLQAADMAPSREAEMVLAKDVVPATETGVALAKDMESPTKPDEALVKDVESSIESDMALVKDVVLPVQTEETAVKDAILPTETDVSLDEDLALSTETEVSAAQDILLFKETESIPPVTMDLASAEGTVPPTDQEMTPVKVAASLSEIEAPLDEDIVSSTEIRSAKEIGLSSETEVALSREMGLPPETEAILDKDMAAPPETEVIVPVKDMAPSPGIETTLAKDVAPRQEIEVTLGKDTVSLPATEMALGRNVALPPETEVTLAKDVAQPPETEVNLANNAALAKFSEAEVVPVPVKDMETAQTQEATSEDSQLKSLQDEGQSAVPLMTSPEAVVAMGQKHSLPTDEDSVLEELEQKKPSSQTSELPSETSGVAKPEEGPPTGSVSGNDITAPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQTAPTTLGGSNKKPMSLASGSVPAAPPKRPAAATSRPSTLPSKDTKPKPVAEAKIPEKRVSPSKPASAPAVKPGSKSTQAVPKAPATATLASPGSTSRNLSTPLPKRPTAIKTEGKPAEIKKMATKSAPADLSRPKSTTTSSVKKSTTVPGTAPPAGAPSRARPTATPPRPSGTPPVDKKPTAAKPTSSAPRLGRVAANASAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAAPARKPEPNAVTKAAGPIGNAQKPPTGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGPPAGEELAIPEAAPEAGAPASASGLSGHTTLAGGGDQREAQTLDSQIQETSI", "length": 1098, "header": "tr|F1MAZ1-1|A0ABI0NJ87_BOVIN Computationally mapped isoform of Microtubule associated protein 4 OS=Bos taurus OX=9913 GN=MAP4 PE=4 SV=5 CANONICAL=A0ABI0NJ87-1" }, "locus": { "chromosome": "22", "start_pos": 51907642, "end_pos": 51815528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021049.8", "url": "https://www.ensembl.org/id/ENSBTAT00000021049.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021049.8", "url": "https://www.ensembl.org/id/ENSBTAP00000021049.8" } ] } }, { "isoform_ac": "F1MAZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87/entry#F1MAZ3-1", "sequence": { "sequence": "MADLSLADALTEPSPEIEEEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGSSESKKKPCSDTSQVEGTPSSQAAVLANGDHGIERNDVTGFPSEFLEEKMAYQGYQNSQNWPENTNFCFEPEHMVNPIQTDPFKMHHDDGLEDSLFFPSGTTNTSAFVEQNDPLKDTYGMLPCDTFAPAAVVPQGWSAEAPNPAHLESFTSPEAVPQPLQPTAEPAEKVEMASGEERAEALEMMMKLQAADMAPSREAEMVLAKDVVPATETGVALAKDMESPTKPDEALVKDVESSIESDMALVKDVVLPVQTEETAVKDAILPTETDVSLDEDLALSTETEVSAAQDILLFKETESIPPVTMDLASAEGTVPPTDQEMTPVKVAASLSEIEAPLDEDIVSSTEIRSAKEIGLSSETEVALSREMGLPPETEAILDKDMAAPPETEVIVPVKDMAPSPGIETTLAKDVAPRQEIEVTLGKDTVSLPATEMALGRNVALPPETEVTLAKDVAQPPETEVNLANNAALAKFSEAEVVPVPVKDMETAQTQEATSEDSQLKSLQDEGQSAVPLMTSPEAVVAMGQKHSLPTDEDSVLEELEQKKPSSQTSELPSETSGVAKPEEGPPTGSVSGNDITAPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQTAPTTLGGSNKKPMSLASGSVPAAPPKRPAAATSRPSTLPSKDTKPKPVAEAKIPEKRVSPSKPASAPAVKPGSKSTQAVPKAPATATLASPGSTSRNLSTPLPKRPTAIKTEGKPAEIKKMATKSAPADLSRPKSTTTSSVKKSTTVPGTAPPAGAPSRARPTATPPRPSGTPPVDKKPTAAKPTSSAPRLGRVAANASAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAAPARKPEPNAVTKAAGPIGNAQKPPTGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGPPAGEELAIPEAAPEAGAPASASGLSGHTTLAGGGDQREAQTLDSQIQETSKWLGLA", "length": 1072, "header": "tr|F1MAZ3-1|A0ABI0NJ87_BOVIN Computationally mapped isoform of Microtubule associated protein 4 OS=Bos taurus OX=9913 GN=MAP4 PE=4 SV=4 CANONICAL=A0ABI0NJ87-1" }, "locus": { "chromosome": "22", "start_pos": 51907533, "end_pos": 51815528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021045.7", "url": "https://www.ensembl.org/id/ENSBTAT00000021045.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021045.7", "url": "https://www.ensembl.org/id/ENSBTAP00000021045.7" } ] } }, { "isoform_ac": "F1N0J2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87/entry#F1N0J2-1", "sequence": { "sequence": "MADLSLADALTEPSPEIEEEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGSSESKKKPCSDTSQVEGTPSSQAAVLANGDHGIERNDVTGFPSEFLEEKMAYQGYQNSQNWPENTNFCFEPEHMVNPIQTDPFKMHHDDGLEDSLFFPSGTTNTSAFVEQNDPLKDTYEPAEKVEMASGEERAEALEMMMKLQAADMAPSREAEMVLAKDVVPATETGVALAKDMESPTKPDEALVKDVESSIESDMALVKDVVLPVQTEETAVKDAILPTETDVSLDEDLALSTETEVSAAQDILLFKETESIPPVTMDLASAEGTVPPTDQEMTPVKVAASLSEIEAPLDEDIVSSTEIRSAKEIGLSSETEVALSREMGLPPETEAILDKDMAAPPETEVIVPVKDMAPSPGIETTLAKDVAPRQEIEVTLGKDTVSLPATEMALGRNVALPPETEVTLAKDVAQPPETEVNLANNAALAKFSEAEVVPVPVKDMETAQTQEATSEDSQLKSLQDEGQSAVPLMTSPEAVVAMGQKHSLPTDEDSVLEELEQKKPSSQTSELPSETSGVAKPEEGPPTGSVSGNDITAPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQTAPTTLGGSNKKPMSLASGSVPAAPPKRPAAATSRPSTLPSKDTKPKPVAEAKIPEKRVSPSKPASAPAVKPGSKSTQAVPKAPATATLASPGSTSRNLSTPLPKRPTAIKTEGKPAEIKKMATKSAPADLSRPKSTTTSSVKKSTTVPGTAPPAGAPSRARPTATPPRPSGTPPVDKKPTAAKPTSSAPRLGRVAANASAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAAPARKPEPNAVTKAAGPIGNAQKPPTGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGPPAGEELAIPEAAPEAGAPASASGLSGHTTLAGGGDQREAQTLDSQIQETSI", "length": 1053, "header": "tr|F1N0J2-1|A0ABI0NJ87_BOVIN Computationally mapped isoform of Microtubule associated protein 4 OS=Bos taurus OX=9913 GN=MAP4 PE=4 SV=3 CANONICAL=A0ABI0NJ87-1" }, "locus": { "chromosome": "22", "start_pos": 51907642, "end_pos": 51815528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030619.7", "url": "https://www.ensembl.org/id/ENSBTAT00000030619.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030594.5", "url": "https://www.ensembl.org/id/ENSBTAP00000030594.5" } ] } }, { "isoform_ac": "G3MY44-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87/entry#G3MY44-1", "sequence": { "sequence": "MADLSLADALTEPSPEIEEEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGSSESKKKPCSDTSQVEGTPSSQAAVLANGDHGIERNDVTGFPSEFLEEKMAYQGYQNSQNWPENTNFCFEPEHMVNPIQTDPFKMHHDDGLEDSLFFPSGTTNTSAFVEQNDPLKDTYGMLPCDTFAPAAVVPQGWSAEAPNPAHLESFTSPEAVPQPLQPTAEPAEKVEMASGEERAEALEMMMKLQAADMAPSREAEMVLAKDVVPATETGVALAKDMESPTKPDEALVKDVESSIESDMALVKDVVLPVQTEETAVKDAILPTETDVSLDEDLALSTETEVSAAQDILLFKETESIPPVTMDLASAEGTVPPTDQEMTPVKVAASLSEIEAPLDEDIVSSTEIRSAKEIGLSSETEVALSREMGLPPETEAILDKDMAAPPETEVIVPVKDMAPSPGIETTLAKDVAPRQEIEVTLGKDTVSLPATEMALGRNVALPPETEVTLAKDVAQPPETEVNLANNAALAKFSEAEVVPVPVKDMETAQTQEATSEDSQLKSLQDEGQSAVPLMTSPEAVVAMGQKHSLPTDEDSVLEELEQKKPSSQTSELPSETSGVAKPEEGPPTGSVSGNDITAPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQTAPTTLGGSNKKPMSLASGSVPAAPPKRPAAATSRPSTLPSKDTKPKPVAEAKIPEKRVSPSKPASAPAVKPGSKSTQAVPKAPATATLASPGSTSRNLSTPLPKRPTAIKTEGKPAEIKKMATKSAPADLSRPKSTTTSSVKKSTTVPGTAPPAGAPSRARPTATPPRPSGTPPVDKKPTAAKPTSSAPRLGRVAANASAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGPPAGEELAIPEAAPEAGAPASASGLSGHTTLAGGGDQREAQTLDSQIQETSI", "length": 1029, "header": "tr|G3MY44-1|A0ABI0NJ87_BOVIN Computationally mapped isoform of Microtubule associated protein 4 OS=Bos taurus OX=9913 GN=MAP4 PE=4 SV=4 CANONICAL=A0ABI0NJ87-1" }, "locus": { "chromosome": "22", "start_pos": 51907642, "end_pos": 51815528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064843.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064843.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054472.4", "url": "https://www.ensembl.org/id/ENSBTAP00000054472.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:281295", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281295", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ87", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ87", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ87", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ87", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ87", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1098, "end_pos": 1100, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1123, "end_pos": 1125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1160, "end_pos": 1162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1235, "end_pos": 1237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1275, "end_pos": 1277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1344, "end_pos": 1346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1452, "end_pos": 1454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 828, "end_pos": 830, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1098, "end_pos": 1100 }, { "start_pos": 1123, "end_pos": 1125 }, { "start_pos": 1160, "end_pos": 1162 }, { "start_pos": 1235, "end_pos": 1237 }, { "start_pos": 1275, "end_pos": 1277 }, { "start_pos": 1344, "end_pos": 1346 }, { "start_pos": 1452, "end_pos": 1454 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 828, "end_pos": 830 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "E1BNN5", "uniprot_id": "E1BNN5_BOVIN", "mass": { "chemical_mass": 159861.0, "monoisotopic_mass": 159861.0 }, "refseq": { "ac": "NP_001193052", "name": "kinesin-like protein KIF27", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193052" }, "gene_names": [ { "name": "KIF27", "type": "recommended", "evidence": [ { "id": "E1BNN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNN5" } ] }, { "name": "KIF27", "type": "synonym", "evidence": [ { "id": "NP_001193052", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193052" } ] } ], "protein_names": [ { "name": "Kinesin family member 27", "type": "synonym", "evidence": [ { "id": "E1BNN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNN5/entry#names_and_taxonomy" } ] }, { "name": "kinesin-like protein KIF27", "type": "synonym", "evidence": [ { "id": "NP_001193052", "database": "RefSeq", "url": 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] }, { "id": "bta:536335", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536335", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YVIMNTF", "url": "https://omabrowser.org/oma/group/YVIMNTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LQV6", "url": "https://www.orthodb.org/?gene=A0A3Q1LQV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MBY8", "url": "https://www.orthodb.org/?gene=A0A3Q1MBY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BNN5", "url": "https://www.orthodb.org/?gene=E1BNN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47969:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47969:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193052", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193052", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQV6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MBY8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MBY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MG55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MG55-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MG55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4N3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4N3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4N3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TST4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TST4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNN5", "url": "https://www.uniprot.org/uniprotkb/E1BNN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNN5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEIPVKVAIRIRPLLCKEVLHNHQACVRVIPNTQQIIIGRDRIFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHVASVVEGQKGIIPRAIQEIFQNISGKPSIDFNIKVSYIEVYKEDLRDLLELETSVKDLHIREDEKGNTVIVGAKECQVESADEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISLCQVDKNRKTAEDGSWHSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRKKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPESDRMDEMEFEIKLLREALQSQQASSSQTSQIHQEGTPDKNKIHSLEEQVTQLQGECLGYQNCLEEAFTFLVDLKDSVRLNEKQQHKLQEWFNMTQEVTLFRGHRGIGNLEEGPQHITVLQLKRELKKCQCALAADEVVFNQKDLEVKELKNQVQMMVQENKGHVVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSMTSSVKETCGDGPDTRILEKRPYTVPFDTRLGHYIYGPVRLDSRKVHTSPSVYSLDRLVAGFRTRSQMLLGRLEEQDEVLQCQFSDNSDDEESEGQEKSEIRHRSCSWIQKPGSVCSLVELNDIQDQTQKSGLENEDLKIECLQESQELNLQKLRNSELILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHEAEQAKVELTETEKQLQELENKDLSDVALKVKLQKEFRRKMDAAKLRVQVLQKKHQNSKKLASLSIQNEKRANELEQNVDHMKYQKVQLQKRLREENEKRKQLDAEIKRDQQKIKELQLKTEQKDLKLKAEDLDAFKMKRRKGSFGSIDQLQKLDKQKKWLDEEVEKVLNQRQELEELEEDLKKREAIVSKKEALLQEKSHLESKKLRSSQALNTDSLKISTRLSLLDQELSEKNVQLQSSTAEEKIKISEQVQALQREKDQLQRQRNSVDEKLKNGSVLSPEEEHVLFQLEEGIEALEAAIEYKNESIQSRQNLLRASFQNLSHSEANVLEKLICLSPVEIRAVLFRYFNKVVNLREVERKLKLQNEEIKMKVLERDNMVRELESALEHLKFQCDRRLILQQKEHEQKMQLLLHHFKERDGEGIVETLKNYEDKIHQLERDLYFYKKTSRDLKKKLKELVGEAIRRQLLPSENHDAGDGVQNPEKAGMVSEELKWASRTESMKLSGRERPLDSSTSSLRTQPNPQKLWEDGPELAPMYSSVAPTSGHLLSNEDKTEIDENQFTKSNSRPSSHIQPVGNVGQLHGVTPVKLCRKELRQISALELSLRRSNLGVAVGSMTADSLEVARKVSDLKT", "length": 1395, "header": "tr|E1BNN5-1|E1BNN5_BOVIN Isoform 1 of Kinesin family member 27 OS=Bos taurus OX=9913 GN=KIF27 PE=3 SV=2 CANONICAL=E1BNN5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQV6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN5/entry#A0A3Q1LQV6-1", "sequence": { "sequence": "MEEIPVKVAIRIRPLLCKEVLHNHQACVRVIPNTQQIIIGRDRIFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHVASVVEGQKGIIPRAIQEIFQNISGKPSIDFNIKVSYIEVYKEDLRDLLELETSVKDLHIREDEKGNTVIVGAKECQVESADEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISLCQVDKNRKTAEDGSWHSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRKKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPESDRMDEMEFEIKLLREALQSQQASSSQTSQIHQEGTPDKNKIHSLEEQVTQLQGECLGYQNCLEEAFTFLVDLKDSVRLNEKQQHKLQEWFNMTQEVTLFRGHRGIGNLEEGPQHITVLQLKRELKKCQCALAADEVVFNQKDLEVKELKNQVQMMVQENKGHVVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSMTSSVKETCGDGPDTRILEKRPYTVPFDTRLGHYIYGPVRLDSRKVHTSPSVYSLDRLVAGFRTRSQMLLGRLEEQDEVLQCQFSDNSDDEESEGQEKSEIRHRSCSWIQKPGSVCSLVELNDIQDQTQKSGLENEDLKIECLQESQELNLQKLRNSELILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHEAEQAKVELTETEKQLQELENKDLSDVALKVKLQKEFRRKMDAAKLRVQVLQKKHQNSKKLASLSIQNEKRANELEQNVDHMKYQKVQLQKRLREENEKRKQLDAEIKRDQQKIKALNTDSLKISTRLSLLDQELSEKNVQLQSSTAEEKIKISEQVQALQREKDQLQRQRNSVDEKLKNGSVLSPEEEHVLFQLEEGIEALEAAIEYKNESIQSRQNLLRASFQNLSHSEANVLEKLICLSPVEIRAVLFRYFNKVVNLREVERKLKLQNEEIKMKVLERDNMVRELESALEHLKFQCDRRLILQQKEHEQKMQLLLHHFKERDGEGIVETLKNYEDKIHQLERDLYFYKKTSRDLKKKLKELVGEAIRRQLLPSENHDAGDGVQNPEKAGMVSEELKWASRTESMKLSGRERPLDSSTSSLRTQPNPQKLWEDGPELAPMYSSVAPTSGHLLSNEDKTEIDENQFTKSNSRPSSHIQPVGNVGQLHGVTPVKLCRKELRQISALELSLRRSNLGVAVGSMTADSLEVARKVSDLKT", "length": 1299, "header": "tr|A0A3Q1LQV6-1|E1BNN5_BOVIN Computationally mapped isoform of Kinesin family member 27 OS=Bos taurus OX=9913 GN=KIF27 PE=3 SV=2 CANONICAL=E1BNN5-1" }, "locus": { "chromosome": "8", "start_pos": 77168917, "end_pos": 77083789, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085629.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085629.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057402.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057402.2" } ] } }, { "isoform_ac": "A0A3Q1MBY8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN5/entry#A0A3Q1MBY8-1", "sequence": { "sequence": "MEEIPVKVAIRIRPLLCKEVLHNHQACVRVIPNTQQIIIGRDRIFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHVASVVEGQKGIIPRAIQEIFQNISGKPSIDFNIKVSYIEVYKEDLRDLLELETSVKDLHIREDEKGNTVIVGAKECQVESADEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISLCQVDKNRKTAEDGSWHSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRKKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPESDRMDEMEFEIKLLREALQSQQASSSQTSQIHQEGTPDKNKIHSLEEQVTQLQGECLGYQNCLEEAFTFLVDLKDSVRLNEKQQHKLQEWFNMTQEVTLFRGHRGIGNLEEGPQHITVLQLKRELKKCQCALAADEVVFNQKDLEVKELKNQVQMMVQENKGHVVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSMTSSVKETCGDGPDTRILEKRPYTVPFDTRLGHYIYGPVRLDSRKVHTSPSVYSLDRLVAGFRTRSQMLLGRLEEQDEVLQCQFSDNSDDEESEGQEKSEIRHRSCSWIQKPGSVCSLVELNDIQDQTQKSGLENEDLKIECLQESQELNLQKLRNSELILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHEAEQAKVELTETEKQLQELENKDLSDVALKVKLQKEFRRKMDAAKLRVQELQLKTEQKDLKLKAEDLDAFKMKRRKGSFGSIDQLQKLDKQKKWLDEEVEKVLNQRQELEELEEDLKKREAIVSKKEALLQEKSHLESKKLRSSQALNTDSLKISTRLSLLDQELSEKNVQLQSSTAEEKIKISEQVQALQREKDQLQRQRNSVDEKLKNGSVLSPEEEHVLFQLEEGIEALEAAIEYKNESIQSRQNLLRASFQNLSHSEANVLEKLICLSPVEIRAVLFRYFNKVVNLREVERKLKLQNEEIKMKVLERDNMVRELESALEHLKFQCDRRLILQQKEHEQKMQLLLHHFKERDGEGIVETLKNYEDKIHQLERDLYFYKKTSRDLKKKLKELVGEAIRRQLLPSENHDAGDGVQNPEKAGMVSEELKWASRTESMKLSGRERPLDSSTSSLRTQPNPQKLWEDGPELAPMYSSVAPTSGHLLSNEDKTEIDENQFTKSNSRPSSHIQPVGNVGQLHGVTPVKLCRKELRQISALELSLRRSNLGVAVGSMTADSLEVARKVSDLKT", "length": 1329, "header": "tr|A0A3Q1MBY8-1|E1BNN5_BOVIN Computationally mapped isoform of Kinesin family member 27 OS=Bos taurus OX=9913 GN=KIF27 PE=3 SV=1 CANONICAL=E1BNN5-1" }, "locus": { "chromosome": "8", "start_pos": 77168917, "end_pos": 77083789, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066979.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066979.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067838.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067838.1" } ] } }, { "isoform_ac": "A0A3Q1MG55-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN5/entry#A0A3Q1MG55-1", "sequence": { "sequence": "MVPGVLEYCLAHTSVVEGQKGIIPRAIQEIFQNISGKPSIDFNIKVSYIEVYKEDLRDLLELETSVKDLHIREDEKGNTVIVGAKECQVESADEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISLCQVDKNRKTAEDGSWHSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRKKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPESDRMDEMEFEIKLLREALQSQQASSSQTSQIHQEGTPDKNKIHSLEEQVTQLQGECLGYQNCLEEAFTFLVDLKDSVRLNEKQQHKLQEWFNMTQEVTLFRGHRGIGNLEEGPQHITVLQLKRELKKCQCALAADEVVFNQKDLEVKELKNQVQMMVQENKGHVVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSMTSSVKETCGDGPDTRILEKRPYTVPFDTRLGHYIYGPVRLDSRKVHTSPSVYSLDRLVAGFRTRSQMLLGRLEEQDEVLQCQFSDNSDDEESEGQEKSEIRHRSCSWIQKPGSVCSLVELNDIQDQTQKSGLENEDLKIECLQESQELNLQKLRNSELILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHEAEQAKVELTETEKQLQELENKDLSDVALKVKLQKEFRRKMDAAKLRVQVLQKKHQNSKKLASLSIQNEKRANELEQNVDHMKYQKVQLQKRLREENEKRKQLDAEIKRDQQKIKELQLKTEQKDLKLKAEDLDAFKMKRRKGSFGSIDQLQKLDKQKKWLDEEVEKVLNQRQELEELEEDLKKREAIVSKKEALLQEKSHLESKKLRSSQALNTDSLKISTRLSLLDQELSEKNVQLQSSTAEEKIKISEQVQALQREKDQLQRQRNSVDEKLKNGSVLSPEEEHVLFQLEEGIEALEAAIEYKNESIQSRQNLLRASFQNLSHSEANVLEKLICLSPVEIRAVLFRYFNKVVNLREVERKLKLQNEEIKMKVLERDNMVRELESALEHLKFQCDRRLILQQKEHEQKMQLLLHHFKERDGEGIVETLKNYEDKIHQLERDLYFYKKTSRDLKKKLKELVGEAIRRQLLPSENHDAGDGVQNPEKAGMVSEELKWASRTESMKLSGRERPLDSSTSSLRTQPNPQKLWEDGPELAPMYSSVAPTSGHLLSNEDKTEIDENQFTKSNSRPSSHIQPVGNVGQLHGVTPVKLCRKELRQISALELSLRRSNLGVAVGSMTADSLEVARKVSDLKT", "length": 1308, "header": "tr|A0A3Q1MG55-1|E1BNN5_BOVIN Computationally mapped isoform of Kinesin family member 27 OS=Bos taurus OX=9913 GN=KIF27 PE=3 SV=1 CANONICAL=E1BNN5-1" }, "locus": { "chromosome": "8", "start_pos": 77160029, "end_pos": 77083789, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079327.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079327.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067971.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067971.2" } ] } }, { "isoform_ac": "A0AAA9T4N3-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN5/entry#A0AAA9T4N3-1", "sequence": { "sequence": "MEEIPVKVAIRIRPLLCKEVLHNHQACVRVIPNTQQIIIGRDRIFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHVASVVEGQKGIIPRAIQEIFQNISGKPSIDFNIKVSYIEVYKEDLRDLLELETSVKDLHIREDEKGNTVIVGAKECQVESADEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISLCQVDKNRKTAEDGSWHSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRKKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPESDRMDEMEFEIKLLREALQSQQASSSQTSQIHQEGTPDKNKIHSLEEQVTQLQGECLGYQNCLEEAFTFLVDLKDSVRLNEKQQHKLQEWFNMTQEVTLFRGHRGIGNLEEGPQHITVLQLKRELKKCQCALAADEVVFNQKDLEVKELKNQVQMMVQENKGHVVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSMTSSVKETCGDGPDTRILEKRPYTVPFDTRLGHYIYGPVRLDSRKVHTSPSVYSLDRLVAGFRTRSQMLLGRLEEQDEVLQCQFSDNSDDEESEGQEKSEIRHRSCSWIQKPGSVCSLVELNDIQDQTQKSGLENEDLKIECLQESQELNLQKLRNSELILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHEAEQAKVELTETEKQLQELENKDLSDVALKVKLQKEFRRKMDAAKLRVQVLQKKHQNSKKLASLSIQNEKRANELEQNVDHMKYQKVQLQKRLREENEKRKQLDAEIKRDQQKIKELQLKTEQKDLKLKAEDLDAFKMKRRKGSFGSIDQLQKLDKQKKWLDEEVEKVLNQRQELEELEEDLKKREAIVSKKEALLQEKSHLESKKLRSSQALNTDSLKISTRLSLLDQELSEKNVQLQSSTAEEKIKISEQVQALQREKDQLQRQRNSVDEKLKNGSVLSPEVVNLREVERKLKLQNEEIKMKVLERDNMVRELESALEHLKFQCDRRLILQQKEHEQKMQLLLHHFKERDGEGIVETLKNYEDKIHQLERDLYFYKKTSRDLKKKLKELVGEAIRRQLLPSENHDAGDGVQNPEKAGMVSEELKWASRTESMKLSGRERPLDSSTSSLRTQPNPQKLWEDGPELAPMYSSVAPTSGHLLSNEDKTEIDENQFTKSNSRPSSHIQPVGNVGQLHGVTPVKLCRKELRQISALELSLRRSNLGVAVGSMTADSLEVARKVSDLKT", "length": 1326, "header": "tr|A0AAA9T4N3-1|E1BNN5_BOVIN Computationally mapped isoform of Kinesin family member 27 OS=Bos taurus OX=9913 GN=KIF27 PE=3 SV=1 CANONICAL=E1BNN5-1" }, "locus": { "chromosome": "8", "start_pos": 77168917, "end_pos": 77083789, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099716.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099716.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091658.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091658.1" } ] } }, { "isoform_ac": "A0AAA9TST4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN5/entry#A0AAA9TST4-1", "sequence": { "sequence": "MEEIPVKVAIRIRPLLCKEVLHNHQACVRVIPNTQQIIIGRDRIFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHVVIVGAKECQVESADEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISLCQVDKNRKTAEDGSWHSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRKKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPESDRMDEMEFEIKLLREALQSQQASSSQTSQIHQEGTPDKNKIHSLEEQVTQLQGECLGYQNCLEEAFTFLVDLKDSVRLNEKQQHKLQEWFNMTQEVTLFRGHRGIGNLEEGPQHITVLQLKRELKKCQCALAADEVVFNQKDLEVKELKNQVQMMVQENKGHVVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSMTSSVKETCGDGPDTRILEKRPYTVPFDTRLGHYIYGPVRLDSRKVHTSPSVYSLDRLVAGFRTRSQMLLGRLEEQDEVLQCQFSDNSDDEESEGQEKSEIRHRSCSWIQKPGSVCSLVELNDIQDQTQKSGLENEDLKIECLQESQELNLQKLRNSELILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHEAEQAKVELTETEKQLQELENKDLSDVALKVKLQKEFRRKMDAAKLRVQVLQKKHQNSKKLASLSIQNEKRANELEQNVDHMKYQKVQLQKRLREENEKRKQLDAEIKRDQQKIKELQLKTEQKDLKLKAEDLDAFKMKRRKGSFGSIDQLQKLDKQKKWLDEEVEKVLNQRQELEELEEDLKKREAIVSKKEALLQEKSHLESKKLRSSQALNTDSLKISTRLSLLDQELSEKNVQLQSSTAEEKIKISEQVQALQREKDQLQRQRNSVDEKLKNGSVLSPEEEHVLFQLEEGIEALEAAIEYKNESIQSRQNLLRASFQNLSHSEANVLEKLICLSPVEIRAVLFRYFNKVVNLREVERKLKLQNEEIKMKVLERDNMVRELESALEHLKFQCDRRLILQQKEHEQKMQLLLHHFKERDGEGIVETLKNYEDKIHQLERDLYFYKKTSRDLKKKLKELVGEAIRRQLLPSENHDAGDGVQNPEKAGMVSEELKWASRTESMKLSGRERPLDSSTSSLRTQPNPQKLWEDGPELAPMYSSVAPTSGHLLSNEDKTEIDENQFTKSNSRPSSHIQPVGNVGQLHGVTPVKLCRKELRQISALELSLRRSNLGVAVGSMTADSLEVARKVSDLKT", "length": 1328, "header": "tr|A0AAA9TST4-1|E1BNN5_BOVIN Computationally mapped isoform of Kinesin family member 27 OS=Bos taurus OX=9913 GN=KIF27 PE=3 SV=1 CANONICAL=E1BNN5-1" }, "locus": { "chromosome": "8", "start_pos": 77168917, "end_pos": 77083789, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114520.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114520.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100119.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100119.1" } ] } }, { "isoform_ac": "E1BNN5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNN5/entry#E1BNN5-1", "sequence": { "sequence": "MEEIPVKVAIRIRPLLCKEVLHNHQACVRVIPNTQQIIIGRDRIFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHVASVVEGQKGIIPRAIQEIFQNISGKPSIDFNIKVSYIEVYKEDLRDLLELETSVKDLHIREDEKGNTVIVGAKECQVESADEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISLCQVDKNRKTAEDGSWHSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRKKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPESDRMDEMEFEIKLLREALQSQQASSSQTSQIHQEGTPDKNKIHSLEEQVTQLQGECLGYQNCLEEAFTFLVDLKDSVRLNEKQQHKLQEWFNMTQEVTLFRGHRGIGNLEEGPQHITVLQLKRELKKCQCALAADEVVFNQKDLEVKELKNQVQMMVQENKGHVVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSMTSSVKETCGDGPDTRILEKRPYTVPFDTRLGHYIYGPVRLDSRKVHTSPSVYSLDRLVAGFRTRSQMLLGRLEEQDEVLQCQFSDNSDDEESEGQEKSEIRHRSCSWIQKPGSVCSLVELNDIQDQTQKSGLENEDLKIECLQESQELNLQKLRNSELILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHEAEQAKVELTETEKQLQELENKDLSDVALKVKLQKEFRRKMDAAKLRVQVLQKKHQNSKKLASLSIQNEKRANELEQNVDHMKYQKVQLQKRLREENEKRKQLDAEIKRDQQKIKELQLKTEQKDLKLKAEDLDAFKMKRRKGSFGSIDQLQKLDKQKKWLDEEVEKVLNQRQELEELEEDLKKREAIVSKKEALLQEKSHLESKKLRSSQALNTDSLKISTRLSLLDQELSEKNVQLQSSTAEEKIKISEQVQALQREKDQLQRQRNSVDEKLKNGSVLSPEEEHVLFQLEEGIEALEAAIEYKNESIQSRQNLLRASFQNLSHSEANVLEKLICLSPVEIRAVLFRYFNKVVNLREVERKLKLQNEEIKMKVLERDNMVRELESALEHLKFQCDRRLILQQKEHEQKMQLLLHHFKERDGEGIVETLKNYEDKIHQLERDLYFYKKTSRDLKKKLKELVGEAIRRQLLPSENHDAGDGVQNPEKAGMVSEELKWASRTESMKLSGRERPLDSSTSSLRTQPNPQKLWEDGPELAPMYSSVAPTSGHLLSNEDKTEIDENQFTKSNSRPSSHIQPVGNVGQLHGVTPVKLCRKELRQISALELSLRRSNLGVAVGSMTADSLEVARKVSDLKT", "length": 1395, "header": "tr|E1BNN5-1|E1BNN5_BOVIN Isoform 1 of Kinesin family member 27 OS=Bos taurus OX=9913 GN=KIF27 PE=3 SV=2 CANONICAL=E1BNN5-1" }, "locus": { "chromosome": "8", "start_pos": 77168917, "end_pos": 77083789, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027236.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027236.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027236.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027236.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1306, "start_aa": "Thr", "end_pos": 1306, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1306", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:536335", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536335", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2U8W8-1", "protein_name": "Kinesin family member 27", "gene_name": "KIF27", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAGMEEIPVKVAVRIRPLLSKEVLHNHQVCVRLVPNTQQIIIGKDRAFTFDFVFGKNSTQGEVYTVCIKPLLLSLTEGYNATVFAYGQTGSGKTYTIGGGHIASIAEDEKGIIPRAIQELFQHISENHNIDFHVKVSYIEVYKEELRDLLELETSVKDLHIREDEKGNTVIVGAKEFQVECADEVMSLLESGNAARHTGTTQMNEHSSRSHAIFTISICQKQSAETQKNTDVPQDPSWKSVRMIASKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPKRKSVHIPYRDAKITRILKDSLGGNAKTVMITCISPSSSDFDESLNSLKYANRAKNIRNKPVVNYNPDQDRIDEMELEIRLLREALQNQQVSNQCSHDLNQERSRISSLEEQLTQLQVQCFSYRNCIDEAFPFLVDLNDDVSLKKSQRDRLQSWITMVQEVRKEVLTMQQADTRTETSHEPHHITVLQLKRELKKCQQALVMDEELFSQKDHELMMLQNQIKALIQENEEHLESLKKAEETQRLQNEKMVEQQILIDQLKEKLERFTVVKMLDITSACEDEPAVVASARRPYSVPLTKSLLHSLHPPSGTETRKVYTSPPAFSLARMMAGFRARSQMILSCIEDQDEVLHCHLSDDSDGEEENTHSKKKSSFKHSINRTWTRKQSSLCLPFELTDMKCQVENSSLSNRSALQNDTATDEEIDSLQKSHVFNMQKLKNSELRLTEAQQKMRELALNIKMKEELIKELVRTGKDAQSVSRQYTLKISKLEQESEQAKTELAETQKQLQELESKELRDIPEKARLQKEFRKKMDAAKLKVQALQKKKQDSKKLASLSNQSEKRATELEQNIVQMKHQQTLLEKRLHEESEKKKQLETEIQRDQRQIKELQLKMEQQQKILTLKDKEIAAFKKKNYSAGTSQKSEKLEEQKKWLDEEMERILQQHRQLAELEEDLKKREAIVAKKEALLQEKSHLEIRKLRSSQALNKDSMKLSSRLSMLDQELCDKSLQLQGSTTEDRTDILEKIQILQKERDQLLTRRNSVDEKLKEGKVLSAEEERILFQLEEGIEALEAAIDYKNESIQSRQHLLRSSSQILSQSEDNIIGKLVALSAAELRAILFRYFNKIVGLRETERKLQLQTEEQEMKVIEQENIIRELESALEHIKLQCDRQLTLQHKEHEKKLQLILHHFKEQDGEGIAETLKEYEVKVQQLEKELFFYKKTSRELKKKLKSFLGESSHQLLPPSKYNSAGDKASSQDEADVASEEFKLKTYCQAGKIKEAERTNTLRTQQNSYQLGEDVSEFGCNKERSSSIVDDRLGEDETQPLKPHSHLPSVIQRRETVTQFQGVTPVKLSRRELRHIPPSELSLRRSSLGAGVSFIAPDSIEMDKK", "length": 1399 }, "evidence": [ { "id": "E1BNN5", "url": "https://omabrowser.org/oma/group/E1BNN5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7JIW4-1", "protein_name": "Kinesin-like protein KIF27", "gene_name": "Kif27", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEEIPVKVAVRIRPLLCKEVLHNHQVCVRDVPNTQQIIIGRDRVFTFDFVFGKNSTQDEVYNICIKPLVLSLVEGYNATVFAYGQTGSGKTYTIGGGHVASVVEDQKGIIPRAIQEIFQSISENPSIDFKIKVSYIEVYKEDLRDLLELETSMKDLHIREDDKGNTVIVGAKECQVESADEVMSLLESGNAARHTSTTQMNEHSSRSHAIFTISIYQAEKSTEAAENGEWHSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSAHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSADFDESLNSLKYANRARNIRNKPTLNFSPESDRMDEMEFEIKLLREALQSHQASISQTSQTPSEGSSDQNRIHSLEEQVAQLQEECLGYQDCIEQAFTFLVDLKDAVRLNQKQQHKLQEWFSRTQEVRKSVLTPFPGHQGVGNLEEGPQHVTVLQLKRELKKYQCAVAADQVMLTQKELEVEELRNQVQLMVQENKGHAVSLKEAQKANRLQNEKLIKQQLLVDQLSEELAKFNLSMTSSDKESCGDGPDARISENRPHTVPFDSHWGHHVYIPSRHDSKKVYSSPPMYSLDQVFDGFQARSQMLMGHLEEQDEVVHCQFSDNSEDEESEGQDKSRIRSRSHSWVKEPGSVCSLVELSDAPDETQKSYLENGDLKMQCLQESQELNLQKLRTSELILNKAKQKMRELTINIRMKEDLIKELIKTGNNAKSVSRQYSLKVTKLEHEAEQARVELTETRKQLQELERKDLSDVALKVKLQKEFRRKMDAAKLRVQVLQKKHQDSKKLASLSIQSEKRASELEQSVGHLKNQKVQLQRRLREESEKKKHLDAELKRDQQKIKELQLKTGQGDGLNTKAEDLDGFNSDRRTGPFRSVDQLQKLDEQKKWLDEEVEKVLNQRQELEQLEEELKKREAIVSKKEALLQEKSHLENKRLRSSQDLSTDSLKISARLNLLEQELSDKSLKLESSTTEEKMKISEQVQALQKERDQLQRQRNAVDEKLASGRVLSPKEEHLLFQLEEGIEALEAAIEFKSESIQNRQDSLRASMQSLSRSEAEVLEKLVCLNITEIRAILFKYFNKVINLREAERKLQLQNKEMKMKVLERDSLVHELESALEHLRLQCDRRLTLQQKEQEQRLQLLLHHFREQDGEGILKTLKKYEEKIQQLEKDLYFYKKTSRDLKKKMIETARGASPWQLSLADPRDAGDGVPNPEEAAGLAGEPKWASGTENAKLNGREREVEDSSSSLKTAALAPQVLEGSPEAALPVGGSLAPPSGRVLSNADNPEERPVPHSQSPPPSQFQPGKDPGQLQGVKPVKLCRRELRQISALELSLRRSSVGAGVLSVTADSLEAPEETNDSKA", "length": 1400 }, "evidence": [ { "id": "E1BNN5", "url": "https://omabrowser.org/oma/group/E1BNN5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LQ93-1", "protein_name": "Kinesin family member 27", "gene_name": "KIF27", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEEIPVKVAVRIRPLLCKEVLHNHQACVRVIPNTQQIIIGRDRVFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHVVSVVEDQKGIIPRAIQEIFQNISENPSIDFTIKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECQVESADEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISLCQVEKNRASAKDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPESDRMDEMEFEIKLLREALQSQQTGNSQTSQIHREGTPDKNRIHSLEEQVAQLQGECLGYQNCIEEAFTFLVDLKDAVRLNQKQQQKLQEWFNMTQEVRKAILTSFRGSGGIGSLGEGPQHITVLQLKRELKKCQCALAADEVVFNQKDLEVKELKNQVQMMVQENKGHVVSLKEAQKVNKLQNEKIIEQQLLVDQLSEELTKLNLSMTSAVKETCGDGPDARIPEKRPYTVPFDTHLGHYIYIPARSDSRKVYTSPSVYSLDRLVAGFRTRSQMLLGHIEEQDEVLHCRFSDNSDDEESEGQEKAEIRHRGCSWIQKPGSVCSLVELNDIQDQTQKSGLENEDLKIECLQESQDLNLQKLRNSELILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHEAEQAKVELTETQKRLQELENKDLSDVALKVKLQKEFRKKMDAAKLRVQVLQKKQQNSKKLASLSIQNEKRANELEQNVDHMKYQKVQLQKRLREENEKRKQLDAEIKRDQQKIKELQLKTEQEEGQQLKAEDSDAFKMKRRKGSFGSIDQLQKLDEQKKWLDEEVEKVLNQRQELEELEEDLKKREAIVSKKEALLQEKSHLESKKLRSSQALNTDSLKISTRLNLLDQELSEKNVQLQSSTAEEKIKISEQVQALQKEKDQLQRRRNSVDEKLKNGSVLSPEEEHVLFQLEEGIEALEAAIEYKNESIQSRQKSLRASFQNLSHSEANVLEKLICLSPAEIRAILFRYFNKVINLREAERKLQLQNEEIKMKLLERDSMVRELESALEHLKLQCDRRLTLQQKEHEQKTQLLLHHFKEQDGEGIMETLKNYEDKIQQLERDLYFYKRTSRDLKKKLKELVGGAIRQQLVPSENHDAGDGVQNPEAEGVVSEELKWASRTESMKLNGRETELDISTSSLRTQPNPQKLWENGPELPPICSSLAPTSGHLLSIEDKTEIDENQFTESLSRPSPQIQPVGNVGQLHGVTPVKLCHKELRQISALELSLRRSSLGVGVGSMSADSIEVVRKTSDLKT", "length": 1401 }, "evidence": [ { "id": "E1BNN5", "url": "https://omabrowser.org/oma/group/E1BNN5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O16844-1", "protein_name": "Kinesin-like protein costa", "gene_name": "cos", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEIPIQVAVRIFPHRELKDLLRSFGPTEPKKDAQAVDEGADSKDSEAQVPAAEKDNPSISETDPNGNAEQDSAADSKTIPDANGNDSGQKDYPDSAYCVQAIPISASALGLPSALPGGDPMDSIAAGLIQVGPHTVPVTHALPSSSSQEQVYHQTVFPLITLFLEGFDASVVTYGQRGQGKSYTLYGNVQDPTLTDSTEGVVQLCVRDIFSHISLHPERTYAINVGFVEICGGDVCDLLGMGNIHCTNVDAVFHWLQVGLSARQSLPAHTLFTLTLEQQWVSKEGLLQHRLSTASFSDLCGTERCGDQPPGRPLDAGLCMLEQVISTLTDPGLMYGVNGNIPYGQTTLTTLLKDSFGGRAQTLVILCVSPLEEHLPETLGNLQFAFKVQCVRNFVIMNTYSDDNTMIVQPAEPVPESNSSAGPLSQAGPGDNFGLQFAASQWSKLVTNAEGLFSKLIDSKLITEVEKEQIEEWLFLKQECEECLSSTEAMRQQKQLVPILEAEEPEDVNSEAANSESPNSDNENDTDNESHRPDLDDKIESLMEEFRDKTDALILEKHAEYLSKHPKAVMQSQDREIEAQPPEENGDDRKVSIGSRRRSVQPGASLSTAELAMLNRVASQQPPPPIDPESVVDPLESSSGEGIRQAALAAAAATAPIEQLQKKLRKLVAEIEGKQRQLREIEETIQVKQNIIAELVKNSDTRSHAKQRFHKKRAKLEAECDKAKKQLGKALVQGRDQSEIERWTTIIGHLERRLEDLSSMKHIAGESGQKVKKLQQSVGESRKQADDLQKKLRKECKLRCQMEAELAKLRESRETGKELVKAQGSPEQQGRQLKAVQARITHLNHILREKSDNLEEQPGPEQQETLRHEIRNLRGTRDLLLEERCHLDRKLKRDKVLTQKEERKLLECDEAIEAIDAAIEFKNEMITGHRSIDTSDRIQREKGEQMLMARLNRLSTEEMRTLLYKYFTKVIDLRDSSRKLELQLVQLERERDAWEWKERVLSNAVRQARLEGERNAVLLQRQHEMKLTLMLRHMAEETSASSASYGERALAPACVAPPVQASSDFDYDHFYKGGGNPSKALIKAPKPMPTGSALDKYKDKEQRSGRNIFAKFHVLTRYASAAAAGSSGSTAEESTALIESTTTATATTTSTTTTGAVGKVKDKALVSFRPEQLKRLMPAPTATKVTRQKNKIIIQDASRRN", "length": 1201 }, "evidence": [ { "id": "E1BNN5", "url": "https://omabrowser.org/oma/group/E1BNN5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M6Z4-1", "protein_name": "Kinesin-like protein KIF27", "gene_name": "Kif27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEIPIKVAVRIRPLLCKEVLHNHQVCVRDIPNTQQIIIGRDRVFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHVASVVEGQKGIIPRAIQEIFQSISENPSIDFKIKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECQVESVEDVMSLLQVGNAARHTGTTQMNEHSSRSHAIFTISVCQVEKNAEAAENGEWYSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPALNISPQADRMDEMEFEIKLLREALQSHQASISQASQASSENVPDQNRIHSLEEQVAQLQEECLGYQDCIEQAFAFLVDLKDAVKLNQKQQHKLQEWFSRTQEVRKAVLTPLPGNQGIGNLEEGPQHLTVLQLKRELKKYQCALAADQVVFTQKDLELEELRTQVQLMMQESKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSAELAKRSLSVPTSAKESCGDGPDARASEKRPHTAPFESHWGHYVYIPSRQDFKKVCSSTPVYSLDQVFAGFRTRSQMLMGHLEDQDEVLHCQFSDNSDDEDSEGQEKPRVRSRSHSWAKKPGSVCSLVELSDTQAESQRSYLGNGDLKMESLQESQEINLQKLRTSELILNKAKQKMRELTINIRMKEDLIKELIKTGNNAKSVSRQYSLKVTKLEHEAEQAKVELTETRKQLQELESKDLSDVALKVKLQKEFRKKMDAAKMRVQVLQKKQQDSKKLASLSIQNEKRASELEHNVDHLKYQKVQLQRRLREEGEKKKQLDAEIKRDQQKIKELQLKAGQGEGLNPKAEDQDGFNLNRRKSPFRSGDQFQKLDEQRKWLDEEVEKVLSQRQELEMLEEDLKKREAIVSKKEALLQEKSLLENKKLRSSQALSTDGLKISARLNLLDQELSEKSLQLESSPTEEKMKISEQVQALQRERDQLQRQRNSVDERLKHGRVLSPKEEHLLFQLEEGIEALEAAIEFKNESIQSRQNSLKASFQNLSQSEANVLEKLVCLNITEIRAILFKYFNKVINLRETERKQQLQNKEMKMKVLERDNVVHELESALEHLRLQCDRRLTLQQKEHEQKMQLLLQHFKDQDGDSIIETLKNYEDKIQQLEKDLYFYKKTSRDLKKRLKDPAQGAAQWQRTLTEHHDAGDGVLNPEETTVLSEELKWASRTENTKLNGSEREVDNSSSSLKTQPLTQQIPEDGPDSLPARSSIAPSSGQLQSIADKTEARPFTHSQSPVPHQFQPVRSIGPLQGVKPVKLCRRELRQISAMELSLRRCSLGAGGRSMTADSLEDPEEN", "length": 1394 }, "evidence": [ { "id": "E1BNN5", "url": "https://omabrowser.org/oma/group/E1BNN5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M6Z5-1", "protein_name": "Kinesin-like protein KIF27", "gene_name": "Kif27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEIPIKVAVRIRPLLCKEVLHNHQVCVRDIPKTQQIIIGRDRVFTFDFVFGKNSTQDEVYSTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHVASVVDGQKGIIPRAIQEIFQSISGNPNIDFKIKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECQVDSVEDVMGLLQVGNAARHTGTTQMNEHSSRSHAIFTISVCQVGKSAEATEDGEWCSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHVPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPQADRMDEMEFEIKLLREALQSHQASISQTSQTASENVPDQNRIHSLEEQIAQLQEECLGYQDCIEQAFAFLVDLKDAVRLNQKQQHKLQQWFSRTQEVRKAVLTPLPGNQSIGNLEEGPQHVTVLQLKRELKKYQCALAADQVVFTQKELELEELRRQMQLMAQESKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELAKRSSSMPTSTKESCGDGPDARAPEKRPHTAPFDSHWGHYVYIPSRQDFKKVCSSSPVYSLDQVFAGFRTRSQMLMGHLEDQDEVLHCQFSDNSDDEDSEGQEKPRVRSRSHSWVKKPGSVCSLVEMSDTQAECQRSYLGNGDLKMESLQESQELNLQKLRTSELILNKAKQKMRELTINIRMKEDLIKELIKTGDNAKSVSRQYSLKVTKLEHEAEQAKVELTETRKQLQELEGKDLSDVALKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRASELEQNVDHLKYQKVQLQRRLREESEKKKQLDAEVKRDQQKLKELQLNAGQGEGLHPKAEDTDAFNLNRRKGPFRSVDQLQKLDEQRKWLDEEVEKVLSQRQELEMLEEELKKREAIVSKKEALLQEKSHLENKKLRSSQALSTDSLKISARLNLLDQELSEKSLLLENSPTEEKVKISEQVQALQREREQLQRQRNSVDEKLRHGRVLSPKEEHLLFQLEEGIEALEAAIEFKNESIQNRQSSLKSSFQNLSQSESNVLEKLVCLNIAEIRAILFKYFNKVINLREAERKQQLQNKEMKMKVLERDNMVHELESALEYLRLQCDRRLTLQQKEHEQKMQLLLHHFKDQDGEGIIETLNKYEDKIQQLEKDLYFYKKTSRDLKKRLKDPVQGAVQWQRTLTEHHDAGDGVLNPEEAAVLSEELKWASRTENTKLNGREKEVDNSSSSLKTPPLTQQILEDGPDSLPVCGSLAPSSGQLQSSADKTEAHAFTQSQSPPPPQLQPVRSIAQLQGVKPVKVCRRELRQISALELTLRRSSLGAGVRSVTADSLEEPEES", "length": 1394 }, "evidence": [ { "id": "E1BNN5", "url": "https://omabrowser.org/oma/group/E1BNN5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86VH2-1", "protein_name": "Kinesin-like protein KIF27", "gene_name": "KIF27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKRELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYEDKIQQLEKDLYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDGVLKPEGGGMLSEELKWASRPESMKLSGREREMDSSASSLRTQPNPQKLWEDIPELPPIHSSLAPPSGHMLGNENKTETDDNQFTKSHSRLSSQIQVVGNVGRLHGVTPVKLCRKELRQISALELSLRRSSLGVGIGSMAADSIEVSRKPRDLKT", "length": 1401 }, "evidence": [ { "id": "E1BNN5", "url": "https://omabrowser.org/oma/group/E1BNN5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BNN5", "url": "https://www.uniprot.org/uniprotkb/E1BNN5" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BNN5", "url": "https://www.uniprot.org/uniprotkb/E1BNN5" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "E1BNN5", "url": "https://www.uniprot.org/uniprotkb/E1BNN5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E1BNN5", "url": "https://www.uniprot.org/uniprotkb/E1BNN5" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "E1BNN5", "url": "https://www.uniprot.org/uniprotkb/E1BNN5" } ], "pmid": "" }, { "name": "microtubule associated complex", "id": "GO:0005875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005875", "evidence": [ { "database": "UniProtKB", "id": "E1BNN5", "url": "https://www.uniprot.org/uniprotkb/E1BNN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "E1BNN5", "url": "https://www.uniprot.org/uniprotkb/E1BNN5" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "E1BNN5", "url": "https://www.uniprot.org/uniprotkb/E1BNN5" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "E1BNN5", "url": "https://www.uniprot.org/uniprotkb/E1BNN5" } ], "pmid": "" }, { "name": "spindle elongation", "id": "GO:0051231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051231", "evidence": [ { "database": "UniProtKB", "id": "E1BNN5", "url": "https://www.uniprot.org/uniprotkb/E1BNN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1037, "end_pos": 1039, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1083, "end_pos": 1085, "annotation": "n_glycosylation_sequon" }, { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1306 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1037, "end_pos": 1039 }, { "start_pos": 1067, "end_pos": 1069 }, { "start_pos": 1083, "end_pos": 1085 }, { "start_pos": 120, "end_pos": 122 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 444, "end_pos": 446 }, { "start_pos": 54, "end_pos": 56 }, { "start_pos": 551, "end_pos": 553 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NJ18-1", "uniprot_ac": "A0ABI0NJ18", "uniprot_id": "A0ABI0NJ18_BOVIN", "mass": { "chemical_mass": 36141.0, "monoisotopic_mass": 36141.0 }, "refseq": { "ac": "XP_005208208", "name": "annexin A3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208208" }, "gene_names": [ { "name": "ANXA3", "type": "recommended", "evidence": [ { "id": "A0ABI0NJ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ] }, { "name": "ANXA3", "type": "synonym", "evidence": [ { "id": "XP_005208208", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208208" } ] } ], "protein_names": [ { "name": "Annexin", "type": "recommended", "evidence": [ { "id": "A0ABI0NJ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18/entry#names_and_taxonomy" } ] }, { "name": "annexin A3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005208208", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208208" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ANXA3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18", "locus": { "chromosome": "6", "start_pos": 93373380, "end_pos": 93301563, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010153", "url": "https://www.ensembl.org/id/ENSBTAG00000010153" } ] } } ], "crossref": [ { "id": "ENSBTAG00000010153", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010153", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "518050", "url": "https://www.ncbi.nlm.nih.gov/gene/518050", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DYNSRFM", "url": "https://omabrowser.org/oma/group/DYNSRFM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MJD9", "url": "https://www.orthodb.org/?gene=A0A3Q1MJD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MWQ2", "url": "https://www.orthodb.org/?gene=F1MWQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005208208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208208", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M636", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M636", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M636-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M636-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJD9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ18-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MWQ2", "url": "https://www.uniprot.org/uniprotkb/F1MWQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MWQ2-1", "url": "https://www.uniprot.org/uniprotkb/F1MWQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASIWVGKRGTIRDYAGFNPSVDAEAIRKAIRGIGTDEKTLISILTERTNAQRLLIAKEYQALCGKELKDDLKGDLSGHFKHLMVALVTPPAVFDAKQLKKSMKGMGTNEDALIEILTTRTSKQMQEIGHAYYTAYKKSLGDEISSETSGDFRKALLILANGRRDESLKVDEQLARKDAQILYNAGEKRWGTDEDAFTDILCLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAIVRCARNTPAFLAERLYRALKGAGTDEFTLNRIMVSRSEIDLLDIRAEFKKLSGYSLYSAIKSDTSGDYEITLLKICGGDD", "length": 323, "header": "tr|A0ABI0NJ18-1|A0ABI0NJ18_BOVIN Isoform 1 of Annexin OS=Bos taurus OX=9913 GN=ANXA3 PE=3 SV=1 CANONICAL=A0ABI0NJ18-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M636-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18/entry#A0A3Q1M636-1", "sequence": { "sequence": "MASIWVGKRGTIRDYAGFNPSVDAEAIRKAIRGIGTDEKTLISILTERTNAQRLLIAKEYQALCGKELKDDLKGDLSGHFKHLMVALVTPPAVFDAKQLKKSMKGMGTNEDALIEILTTRTSKQMQEIGHAYYTAYKKSLGDEISSETSGDFRKALLILANGRRDESLKVDEQLARKDAQILYNAGEKRWGTDEDAFTDILCLRSFPQLKLIRCARNTPAFLAERLYRALKGAGTDEFTLNRIMVSRSEIDLLDIRAEFKKLSGYSLYSAIKSDTSGDYEITLLKICGGDD", "length": 291, "header": "tr|A0A3Q1M636-1|A0ABI0NJ18_BOVIN Computationally mapped isoform of Annexin OS=Bos taurus OX=9913 GN=ANXA3 PE=3 SV=1 CANONICAL=A0ABI0NJ18-1" }, "locus": { "chromosome": "6", "start_pos": 93373038, "end_pos": 93306512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084625.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084625.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069186.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069186.2" } ] } }, { "isoform_ac": "A0A3Q1MJD9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18/entry#A0A3Q1MJD9-1", "sequence": { "sequence": "PVGIWEYVGKRGTIRDYAGFNPSVDAEAIRKAIRGIGTDEKTLISILTERTNAQRLLIAKEYQALCGKELKDDLKGDLSGHFKHLMVALVTPPAVFDAKQLKKSMKGMGTNEDALIEILTTRTSKQMQEIGHAYYTAYKKSLGDEISSETSGDFRKALLILANGRRDESLKVDEQLARKDAQILYNAGEKRWGTDEDAFTDILCLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAIVRCARNTPAFLAERLYRALKGAGTDEFTLNRIMVSRSEIDLLDIRAEFKKLSGYSLYSAIKSDTSGDYEITLLKICGGDD", "length": 325, "header": "tr|A0A3Q1MJD9-1|A0ABI0NJ18_BOVIN Computationally mapped isoform of Annexin OS=Bos taurus OX=9913 GN=ANXA3 PE=3 SV=2 CANONICAL=A0ABI0NJ18-1" }, "locus": { "chromosome": "6", "start_pos": 93373038, "end_pos": 93328637, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068611.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068611.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071451.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071451.2" } ] } }, { "isoform_ac": "A0ABI0NJ18-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18/entry#A0ABI0NJ18-1", "sequence": { "sequence": "MASIWVGKRGTIRDYAGFNPSVDAEAIRKAIRGIGTDEKTLISILTERTNAQRLLIAKEYQALCGKELKDDLKGDLSGHFKHLMVALVTPPAVFDAKQLKKSMKGMGTNEDALIEILTTRTSKQMQEIGHAYYTAYKKSLGDEISSETSGDFRKALLILANGRRDESLKVDEQLARKDAQILYNAGEKRWGTDEDAFTDILCLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAIVRCARNTPAFLAERLYRALKGAGTDEFTLNRIMVSRSEIDLLDIRAEFKKLSGYSLYSAIKSDTSGDYEITLLKICGGDD", "length": 323, "header": "tr|A0ABI0NJ18-1|A0ABI0NJ18_BOVIN Isoform 1 of Annexin OS=Bos taurus OX=9913 GN=ANXA3 PE=3 SV=1 CANONICAL=A0ABI0NJ18-1" }, "locus": { "chromosome": "6", "start_pos": 93373038, "end_pos": 93306512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137536.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137536.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104046.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104046.1" } ] } }, { "isoform_ac": "F1MWQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18/entry#F1MWQ2-1", "sequence": { "sequence": "MASIWVGKRGTIRDYAGFNPSVDAEAIRKAIRGIGTDEKTLISILTERTNAQRLLIAKEYQALCGKELKDDLKGDLSGHFKHLMVALVTPPAVFDAKQLKKSMKGMGTNEDALIEILTTRTSKQMQEIGHAYYTAYKKSLGDEISSETSGDFRKALLILANILYNAGEKRWGTDEDAFTDILCLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAIVRCARNTPAFLAERLYRALKGAGTDEFTLNRIMVSRSEIDLLDIRAEFKKLSGYSLYSAIKSDTSGDYEITLLKICGGDD", "length": 304, "header": "tr|F1MWQ2-1|A0ABI0NJ18_BOVIN Computationally mapped isoform of Annexin OS=Bos taurus OX=9913 GN=ANXA3 PE=3 SV=2 CANONICAL=A0ABI0NJ18-1" }, "locus": { "chromosome": "6", "start_pos": 93373038, "end_pos": 93306512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045455.3", "url": "https://www.ensembl.org/id/ENSBTAT00000045455.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042843.2", "url": "https://www.ensembl.org/id/ENSBTAP00000042843.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "O35639-1", "protein_name": "Annexin A3", "gene_name": "Anxa3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASIWVGPRGTIKDYPGFSPSVDAEAIRKAIRGLGTDEKTLINILTERSNAQRQLIVKQYQAAYEQELKDDLKGDLSGHFEHVMVALVTAPALFDAKQLKKSMKGTGTDEDALIEILTTRSSRQMKEISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKKDAQILYNAGENKWGTDEDKFTEVLCLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAIVHCARNTPAFLAERLHQALKGAGTDEFTLNRIMVSRSEIDLLDIRHEFKKHYGYSLYSAIQSDTSGDYRTVLLKICGEDD", "length": 323 }, "evidence": [ { "id": "A0ABI0NJ18", "url": "https://omabrowser.org/oma/group/A0ABI0NJ18/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P12429-1", "protein_name": "Annexin A3", "gene_name": "ANXA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASIWVGHRGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKELKDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAGENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNCVRNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSDTSGDYEITLLKICGGDD", "length": 323 }, "evidence": [ { "id": "A0ABI0NJ18", "url": "https://omabrowser.org/oma/group/A0ABI0NJ18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P14669-1", "protein_name": "Annexin A3", "gene_name": "Anxa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASLWVGPRGTINNYPGFNPSVDAEAIRKAIKGIGTDEKTLINILTERSNAQRQLIVKQYQEAYEQALKADLKGDLSGHFEHVMVALITAPAVFDAKQLKKSMRGMGTDEDTLIEILTTRTSRQMKEISQAYYTAYKKNLRDDISSETSGDFRKALLTLADGGRDESLKVDEHLAKKDAQTLYDAGEKKWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAVVRCTRNTPAFLAGRLHQALKGAGTDEFTLNRIMVSRSEIDLLDIRREFKKHYGCSLYSAIQSDTSGDYRTVLLKICGGDD", "length": 324 }, "evidence": [ { "id": "A0ABI0NJ18", "url": "https://omabrowser.org/oma/group/A0ABI0NJ18/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "specific granule", "id": "GO:0042581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042581", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "chromaffin granule membrane", "id": "GO:0042584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042584", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "vesicle membrane", "id": "GO:0012506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012506", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "neutrophil degranulation", "id": "GO:0043312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043312", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell migration", "id": "GO:0010595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010595", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "phospholipase inhibitor activity", "id": "GO:0004859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004859", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ18", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLX1-1", "uniprot_ac": "E1BLX1", "uniprot_id": "E1BLX1_BOVIN", "mass": { "chemical_mass": 93443.0, "monoisotopic_mass": 93443.0 }, "refseq": { "ac": "NP_001104256", "name": "intraflagellar transport protein 88 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104256" }, "gene_names": [ { "name": "IFT88", "type": "recommended", "evidence": [ { "id": "E1BLX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLX1" } ] }, { "name": "IFT88", "type": "synonym", "evidence": [ { "id": "NP_001104256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104256" } ] } ], "protein_names": [ { "name": "Intraflagellar transport protein 88 homolog", "type": "recommended", "evidence": [ { "id": "E1BLX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLX1/entry#names_and_taxonomy" } ] }, { "name": "Tetratricopeptide repeat protein 10", "type": "synonym", "evidence": [ { "id": "E1BLX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLX1/entry#names_and_taxonomy" } ] }, { "name": "intraflagellar transport 88 homolog", "type": "synonym", "evidence": [ { "id": "NP_001104256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104256" } ] }, { "name": "intraflagellar transport protein 88 homolog", "type": "synonym", "evidence": [ { "id": "NP_001104256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104256" } ] } ], "function": [ { "annotation": "Positively regulates primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MNB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB3#function" }, { "database": "UniProtKB", "id": "ARBA00059531", "url": "https://www.uniprot.org/uniprotkb/ARBA00059531#function" }, { "database": "UniProtKB", "id": "E1BLX1", "url": "https://www.uniprot.org/uniprotkb/E1BLX1#function" }, { "database": "UniProtKB", "id": "A0A3Q1MMQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMQ6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLX1", "url": "https://www.uniprot.org/uniprotkb/E1BLX1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IFT88", "url": "https://www.uniprot.org/uniprotkb/E1BLX1", "locus": { "chromosome": "12", "start_pos": 35853118, "end_pos": 35914653, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014286", "url": "https://www.ensembl.org/id/ENSBTAG00000014286" } ] } } ], "crossref": [ { "id": "E1BLX1", "url": "https://alphafold.ebi.ac.uk/entry/E1BLX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014286", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014286", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "514177", "url": "https://www.ncbi.nlm.nih.gov/gene/514177", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514177", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514177", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RIKIMHN", "url": "https://omabrowser.org/oma/group/RIKIMHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MMQ6", "url": "https://www.orthodb.org/?gene=A0A3Q1MMQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MNB3", "url": "https://www.orthodb.org/?gene=A0A3Q1MNB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BLX1", "url": "https://www.orthodb.org/?gene=E1BLX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44117:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44117:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9646399", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9646399", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001104256", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104256", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLX1", "url": "https://www.uniprot.org/uniprotkb/E1BLX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLX1-1", "url": "https://www.uniprot.org/uniprotkb/E1BLX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMQNVHLAPETDEDDLYSGYNDYNPTYDTEELENDTAFQQAVRTSHGRRPPITAKIPSTAVSRPVATGYGSKTSLASSMGRPMTGAIQDGVTRPMTAVRAAGFTKGALRGSAFDPLGQSWGPAPPLEARNEDSPEEKIRQLEKKVNELVEESCIANSCGDLKLALEKAKDAGRKERVLVRQREQVTRPENINLDLTYSVLFNLASQYSANEMYAEALNTYQVIVKNKMFSNAGRLKVNMGNIYLKQRNYSKAIKFYRMALDQIPSVHKEMRIKIMQNIGVTFIKTGQYSDAISSFEHIMSMAPNLKAGFNLILSYFAIGDREKMKKSFQKLIAVPLEIDEDDKYISPSDDPHTNLVIEAIKNDHLRQMERERKAMAEKYIMTAAKLIAPVIETSFAVGYDWCVEVVKASQYVELANDLEINKAITYLRQKDFNQAVETLKMFEKKDSRVKSAAATNLSFLYYLENEFAQASSYADLAVNSDRYNPSALTNKGNTVFANGDYEKAAEFYKEALRNDCSCTEALYNIGLTYKKLNRLDEALDCFLKLHAILRNSAQVLYQIANVYELMEDPSQAMEWLMQLISVVPTDSRALSKLGGLYDSEGDKSQAFQYYYESYRYFPSNIEVIEWLGAYYIDTQFCEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKDIHRKFPENVECLRFLVRLCTDIGLKEVQEYATKLKRLEKMKEIREQRIKSGRDSSGCPRGRRDGSAGSDSGQNCSAGSKGERLSAQLRALPGTDEPYESSSNKEPDAFYVDPLGPQIERPKTAAKKRMEEDDFADEELGDDLLPE", "length": 825, "header": "tr|E1BLX1-1|E1BLX1_BOVIN Isoform 1 of Intraflagellar transport protein 88 homolog OS=Bos taurus OX=9913 GN=IFT88 PE=4 SV=2 CANONICAL=E1BLX1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MMQ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BLX1/entry#A0A3Q1MMQ6-1", "sequence": { "sequence": "MMQNVHLAPETDEDDLYSGYNDYNPTYDTEELENDTAFQQAVRTSHGRRPPDGVTRPMTAVRAAGFTKGALRGSAFDPLGQSWGPAPPLEARNEDSPEEKIRQLEKKVNELVEESCIANSCGDLKLALEKAKDAGRKERVLVRQREQVTRPENINLDLTYSVLFNLASQYSANEMYAEALNTYQVIVKNKMFSNAGRLKVNMGNIYLKQRNYSKAIKFYRMALDQIPSVHKEMRIKIMQNIGVTFIKTGQYSDAISSFEHIMSMAPNLKAGFNLILSYFAIGDREKMKKSFQKLIAVPLEIDEDDKYISPSDDPHTNLVIEAIKNDHLRQMERERKAMAEKYIMTAAKLIAPVIETSFAVGYDWCVEVVKASQYVELANDLEINKAITYLRQKDFNQAVETLKMFEKKDSRVKSAAATNLSFLYYLENEFAQASSYADLAVNSDRYNPSALTNKGNTVFANGDYEKAAEFYKEALRNDCSCTEALYNIGLTYKKLNRLDEALDCFLKLHAILRNSAQVLYQIANVYELMEDPSQAMEWLMQLISVVPTDSRALSKLGGLYDSEGDKSQAFQYYYESYRYFPSNIEVIEWLGAYYIDTQFCEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKDIHRKFPENVECLRFLVRLCTDIGLKEVQEYATKLKRLEKMKEIREQRIKSGRDSSGCPRGRRDGSAGSDSGQNCSAGSKGERLSAQLRALPGTDEPYESSSNKEPDAFYVDPLGPQIERPKTAAKKRMEEDDFADEELGDDLLPE", "length": 788, "header": "tr|A0A3Q1MMQ6-1|E1BLX1_BOVIN Computationally mapped isoform of Intraflagellar transport protein 88 homolog OS=Bos taurus OX=9913 GN=IFT88 PE=4 SV=2 CANONICAL=E1BLX1-1" }, "locus": { "chromosome": "12", "start_pos": 35908774, "end_pos": 35853308, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067455.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067455.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073104.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073104.2" } ] } }, { "isoform_ac": "A0A3Q1MNB3-1", "url": "https://www.uniprot.org/uniprotkb/E1BLX1/entry#A0A3Q1MNB3-1", "sequence": { "sequence": "MMQNVHLAPETDEDDLYSGYNDYNPTYDTEELENDTAFQQAVRTSHGRRPPSKTSLASSMGRPMTGAIQDGVTRPMTAVRAAGFTKGALRGSAFDPLGQSWGPAPPLEARNEDSPEEKIRQLEKKVNELVEESCIANSCGDLKLALEKAKDAGRKERVLVRQREQVTRPENINLDLTYSVLFNLASQYSANEMYAEALNTYQVIVKNKMFSNAGRLKVNMGNIYLKQRNYSKAIKFYRMALDQIPSVHKEMRIKIMQNIGVTFIKTGQYSDAISSFEHIMSMAPNLKAGFNLILSYFAIGDREKMKKSFQKLIAVPLEIDEDDKYISPSDDPHTNLVIEAIKNDHLRQMERERKAMAEKYIMTAAKLIAPVIETSFAVGYDWCVEVVKASQYVELANDLEINKAITYLRQKDFNQAVETLKMFEKKDSRVKSAAATNLSFLYYLENEFAQASSYADLAVNSDRYNPSALTNKGNTVFANGDYEKAAEFYKEALRNDCSCTEALYNIGLTYKKLNRLDEALDCFLKLHAILRNSAQVLYQIANVYELMEDPSQAMEWLMQLISVVPTDSRALSKLGGLYDSEGDKSQAFQYYYESYRYFPSNIEVIEWLGAYYIDTQFCEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKDIHRKFPENVECLRFLVRLCTDIGLKEVQEYATKLKRLEKMKEIREQRIKSGRDSSGCPRGRRDGSAGSDSGQNCSAGSKGERLSAQLRALPGTDEPYESSSNKEPDAFYVDPLGPQIERPKTAAKKRMEEDDFADEELGDDLLPE", "length": 806, "header": "tr|A0A3Q1MNB3-1|E1BLX1_BOVIN Computationally mapped isoform of Intraflagellar transport protein 88 homolog OS=Bos taurus OX=9913 GN=IFT88 PE=4 SV=2 CANONICAL=E1BLX1-1" }, "locus": { "chromosome": "12", "start_pos": 35908774, "end_pos": 35853308, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078675.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078675.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073403.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073403.2" } ] } }, { "isoform_ac": "E1BLX1-1", "url": "https://www.uniprot.org/uniprotkb/E1BLX1/entry#E1BLX1-1", "sequence": { "sequence": "MMQNVHLAPETDEDDLYSGYNDYNPTYDTEELENDTAFQQAVRTSHGRRPPITAKIPSTAVSRPVATGYGSKTSLASSMGRPMTGAIQDGVTRPMTAVRAAGFTKGALRGSAFDPLGQSWGPAPPLEARNEDSPEEKIRQLEKKVNELVEESCIANSCGDLKLALEKAKDAGRKERVLVRQREQVTRPENINLDLTYSVLFNLASQYSANEMYAEALNTYQVIVKNKMFSNAGRLKVNMGNIYLKQRNYSKAIKFYRMALDQIPSVHKEMRIKIMQNIGVTFIKTGQYSDAISSFEHIMSMAPNLKAGFNLILSYFAIGDREKMKKSFQKLIAVPLEIDEDDKYISPSDDPHTNLVIEAIKNDHLRQMERERKAMAEKYIMTAAKLIAPVIETSFAVGYDWCVEVVKASQYVELANDLEINKAITYLRQKDFNQAVETLKMFEKKDSRVKSAAATNLSFLYYLENEFAQASSYADLAVNSDRYNPSALTNKGNTVFANGDYEKAAEFYKEALRNDCSCTEALYNIGLTYKKLNRLDEALDCFLKLHAILRNSAQVLYQIANVYELMEDPSQAMEWLMQLISVVPTDSRALSKLGGLYDSEGDKSQAFQYYYESYRYFPSNIEVIEWLGAYYIDTQFCEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKDIHRKFPENVECLRFLVRLCTDIGLKEVQEYATKLKRLEKMKEIREQRIKSGRDSSGCPRGRRDGSAGSDSGQNCSAGSKGERLSAQLRALPGTDEPYESSSNKEPDAFYVDPLGPQIERPKTAAKKRMEEDDFADEELGDDLLPE", "length": 825, "header": "tr|E1BLX1-1|E1BLX1_BOVIN Isoform 1 of Intraflagellar transport protein 88 homolog OS=Bos taurus OX=9913 GN=IFT88 PE=4 SV=2 CANONICAL=E1BLX1-1" }, "locus": { "chromosome": "12", "start_pos": 35908774, "end_pos": 35853308, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018980.7", "url": "https://www.ensembl.org/id/ENSBTAT00000018980.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018980.5", "url": "https://www.ensembl.org/id/ENSBTAP00000018980.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514177", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514177", "resource": "KEGG Pathway" }, { "id": "R-BTA-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" }, { "id": "R-BTA-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620924", "resource": "Reactome", "description": "Intraflagellar transport" }, { "id": "R-BTA-9646399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9646399", "resource": "Reactome", "description": "Aggrephagy" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M9B4-1", "protein_name": "Intraflagellar transport protein 88 homolog", "gene_name": "Ift88", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMENVHLAPETDEDDLYSGFNDYNPAYDTEELENDTGFQQAVRTSHGRRPPVTAKIPSTAVSRPIATGYGSKTSLASSMGRPMTGTIQDGVARPMTAVRAAGFSKAALRGSAFDPLGQSRGPAPPLEAKNEDSPEEKIRQLEKKVNELVEESCIANSCGDLKLALEKAKDAGRKERVLVRQREQVTTPENINLDLTYSVLFNLASQYSANEMYAEALNTYQVIVKNKMFSNAGRLKVNMGNIYLKQRNYSKAIKFYRMALDQIPSVHKEMRIKIMQNIGITFIKTGQYSDAINSFEHIMSMAPNLKAGFNLILSCFAIGDREKMKKAFQKLIAVPLEIDEDDKYISPSDDPHTNLLVEAIKNDHLRQMERERKAMAEKYIMTAAKLIAPVIESSFAVGYNWCVEVVKASQYVELANDLEINKAITYLRQKDFNQAVDTLKMFEKKDSRVKSAAATNLSFLYYLENEFAQASSYADLAVNSDRYNPSALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYKKLNRLDEALDSFLKLHAILRNSAQVLCQIANVYELMEDPNQAIEWLMQLISVVPTDSQALSKLGELYDSEGDKSQAFQYYYESYRYFPSNIEVIEWLGAYYIDTQFCEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKEIHRKFPENVECLRFLVRLCTDIGLKEVQEYATKLKRLEKMKEMREQRIKSGRDSGGGSRSKREGSAGSDSGQSNSASSKSERLSAKLRALPGTDEPYESSSNKEIDASYVDPLGPQIERPKTAAKKRIDEDDFADEELGDDLLPE", "length": 825 }, "evidence": [ { "id": "E1BLX1", "url": "https://omabrowser.org/oma/group/E1BLX1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q13099-2", "protein_name": "Intraflagellar transport protein 88 homolog", "gene_name": "IFT88", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQNVHLAPETDEDDLYSGYNDYNPIYDIEELENDAAFQQAVRTSHGRRPPITAKISSTAVTRPIATGYGSKTSLASSIGRPMTGAIQDGVTRPMTAVRAAGFTKAALRGSAFDPLSQSRGPASPLEAKKKDSPEEKIKQLEKEVNELVEESCIANSCGDLKLALEKAKDAGRKERVLVRQREQVTTPENINLDLTYSVLFNLASQYSVNEMYAEALNTYQVIVKNKMFSNAGILKMNMGNIYLKQRNYSKAIKFYRMALDQVPSVNKQMRIKIMQNIGVTFIQAGQYSDAINSYEHIMSMAPNLKAGYNLTICYFAIGDREKMKKAFQKLITVPLEIDEDKYISPSDDPHTNLVTEAIKNDHLRQMERERKAMAEKYIMTSAKLIAPVIETSFAAGYDWCVEVVKASQYVELANDLEINKAVTYLRQKDYNQAVEILKVLEKKDSRVKSAAATNLSALYYMGKDFAQASSYADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEALDCFLKLHAILRNSAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYESYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKDTHRKFPENVECLRFLVRLCTDLGLKDAQEYARKLKRLEKMKEIREQRIKSGRDGSGGSRGKREGSASGDSGQNYSASSKGERLSARLRALPGTNEPYESSSNKEIDASYVDPLGPQIERPKTAAKKRIDEDDFADEELGDDLLPE", "length": 824 }, "evidence": [ { "id": "E1BLX1", "url": "https://omabrowser.org/oma/group/E1BLX1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61371-1", "protein_name": "Intraflagellar transport protein 88 homolog", "gene_name": "Ift88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENVHLAPETDEDDLYSGFNDYNPAYDTEELENDTGFQQAVRTSHGRRPPVTAKIPSTAVSRPIATGYGSKTSLTSSMGRPMTGTIQDGVARPMTAVRAAGFSKAALRGSAFDPLGQSRGPAPPLEAKNEDSPEEKIRQLEKKVNELVEESCIANSCGDLKLALEKAKDAGRKERVLVRQREQVTSPENINLDLTYSVLFNLASQYSANEMYAEALNTYQVIVKNKMFSNAGRLKVNMGNIYLKQRNYSKAIKFYRMALDQIPSVHKEMRIKIMQNIGITFIKTGQYSDAINSFEHIMSMAPSLKAGFNLILSCFAIGDREKMKKAFQKLIAVPLEIDEDDKYISPSDDPHTNLLIEAIKNDHLRQMERERKAMAEKYIMTAAKLIAPVIEASFAVGYNWCVEVVKASQYVELANDLEINKAITYLRQKDFNQAVDTLKMFEKKDSRVKSAAATNLSFLYYLENEFAQASSYADLAVNSDRYNPSALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYKKLNRLDEALDSFLKLHAILRNSAQVLCQIANIYELMEDPNQAIEWLMQLISVVPTDSQALSKLGELYDSEGDKSQAFQYYYESYRYFPSNIEVIEWLGAYYIDTQFCEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKEIHRKFPENVECLRFLVRLCTDIGLKEVQEYATKLKRLEKMKEMREQRIKSGRDSSGGSRSKREGSAGSDSGQNNSASSKSERLSAKLRALPGTDEPYESSGNKEIDASYVDPLGPQIERPKTAAKKRIDEDDFADEELGDDLLPE", "length": 824 }, "evidence": [ { "id": "E1BLX1", "url": "https://omabrowser.org/oma/group/E1BLX1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7KRS6-1", "protein_name": "No mechanoreceptor potential B, isoform D", "gene_name": "nompB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSQITANGTQRLPEPVSEHEAVPPPPPTAAGRPRPPTSQLFSRGNLASSRATGGDKSGLARPSTAVRAVGYAANCESAHQRFEQFFLEKAKQQTLSSRAAVDAIKDVNPQMKYKNLEEKIVKLLESSIVLAWQGSPNKLLNLDTKLAEALSKAKEAFSLDRTLHQFRDQHGENVYHNFDLTYAQYERSEMHIEALNTYSIMAKNKMFPHVNQLKLNMGNIYYSMGIYQKAVKMYRMALDSVPKSLSQLRLKIRENIGILFIRMGSYSDAASSFEFIMTERANIRSSIHLLLCYFALGDVEKVKLAFRRLCDVQTEAIESDMESETNIIKLQQQAEPIQQIGETDGYQSLNNEPVTGSVIKAEGGGKLNETVKFAATVKHRYVVQALKKDELAVYRNERRNAVKRSITMIVDLISPFIEDNYNDGYNWCIEIIKTSNLAWLANELELNKALVYLRQNDVHQAIETLQMYDRKSEGSMTASALTNLSFIYIKMASHCVNQLHEIGSLKNNAPGLINAGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFELLKEQLMLPSSVQHSHVFYQLAKLQERRLESGLISNFTPGAALQAYLQVVGISASDIDSRLFEKVGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERALFYYERAVLADPNDPNLMLRIASCFRNSYLPTKQYLGLFQKIHARFPDNLTCIRALMQVTKSLELGDLYERYASEYTRLQSQQQERQSEQRYQQQRFPSAAKFSNRLRSIRQSNEEHLKEVGENFNSVVHTQSPYTSILQFDPLGPPAERPKTGRPLQSRDDVDDDAEMNPESLLPI", "length": 857 }, "evidence": [ { "id": "E1BLX1", "url": "https://omabrowser.org/oma/group/E1BLX1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BLX1", "url": "https://www.uniprot.org/uniprotkb/E1BLX1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BLX1", "url": "https://www.uniprot.org/uniprotkb/E1BLX1" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "E1BLX1", "url": "https://www.uniprot.org/uniprotkb/E1BLX1" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1BLX1", "url": 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"MAAAEAANCIMENFVATLANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR", "length": 371, "header": "tr|A0ABZ3NNC5-1|A0ABZ3NNC5_BOVIN Isoform 1 of type I protein arginine methyltransferase OS=Bos taurus OX=9913 GN=PRMT1 PE=4 SV=1 CANONICAL=A0ABZ3NNC5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MR38-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5/entry#A0A3Q1MR38-1", "sequence": { "sequence": "MAAAEAANCIMEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSEAGRRGAGTVGPATGVVRGSPGGLEASDSSSAGQSECTVLQSLRPRKSPSQA", "length": 338, "header": "tr|A0A3Q1MR38-1|A0ABZ3NNC5_BOVIN Computationally mapped isoform of type I protein arginine methyltransferase OS=Bos taurus OX=9913 GN=PRMT1 PE=4 SV=3 CANONICAL=A0ABZ3NNC5-1" }, "locus": { "chromosome": "18", "start_pos": 56087566, "end_pos": 56079592, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068896.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068896.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074556.3", "url": "https://www.ensembl.org/id/ENSBTAP00000074556.3" } ] } }, { "isoform_ac": "A0AAA9T6K5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5/entry#A0AAA9T6K5-1", "sequence": { "sequence": "MAAAEAANCIMEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR", "length": 285, "header": "tr|A0AAA9T6K5-1|A0ABZ3NNC5_BOVIN Computationally mapped isoform of type I protein arginine methyltransferase OS=Bos taurus OX=9913 GN=PRMT1 PE=4 SV=1 CANONICAL=A0ABZ3NNC5-1" }, "locus": { "chromosome": "18", "start_pos": 56089423, "end_pos": 56079592, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095207.2", "url": "https://www.ensembl.org/id/ENSBTAT00000095207.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093522.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093522.1" } ] } }, { "isoform_ac": "A0ABZ3NNC5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5/entry#A0ABZ3NNC5-1", "sequence": { "sequence": "MAAAEAANCIMENFVATLANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR", "length": 371, "header": "tr|A0ABZ3NNC5-1|A0ABZ3NNC5_BOVIN Isoform 1 of type I protein arginine methyltransferase OS=Bos taurus OX=9913 GN=PRMT1 PE=4 SV=1 CANONICAL=A0ABZ3NNC5-1" }, "locus": { "chromosome": "18", "start_pos": 56089423, "end_pos": 56079592, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072194.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072194.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067842.3", "url": "https://www.ensembl.org/id/ENSBTAP00000067842.3" } ] } }, { "isoform_ac": "F6RFE5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5/entry#F6RFE5-1", "sequence": { "sequence": "MVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR", "length": 342, "header": "tr|F6RFE5-1|A0ABZ3NNC5_BOVIN Computationally mapped isoform of type I protein arginine methyltransferase OS=Bos taurus OX=9913 GN=PRMT1 PE=4 SV=3 CANONICAL=A0ABZ3NNC5-1" }, "locus": { "chromosome": "18", "start_pos": 56089423, "end_pos": 56082249, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008734.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008734.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008734.7", "url": "https://www.ensembl.org/id/ENSBTAP00000008734.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:520388", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520388", "resource": "KEGG Pathway" }, { "id": "R-BTA-3214858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214858", "resource": "Reactome", "description": "RMTs methylate histone arginines" }, { "id": "R-BTA-8936459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8936459", "resource": "Reactome", "description": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" }, { "id": "R-BTA-9009391", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9009391", "resource": "Reactome", "description": "Extra-nuclear estrogen signaling" }, { "id": "R-BTA-9018519", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9018519", "resource": "Reactome", "description": "Estrogen-dependent gene expression" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNC5", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNC5", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNC5", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNC5", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNC5", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNC5", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-arginine omega-N asymmetric methyltransferase activity", "id": "GO:0035242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035242", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNC5", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNC5", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5" } ], "pmid": "" }, { "name": "protein-arginine omega-N monomethyltransferase activity", "id": "GO:0035241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035241", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNC5", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48096", "name": "", "equation": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABZ3NNC5-1", "A0A3Q1MWG1-1", "Q5E9L5-1", "F1MEB9-1", "F1MQ97-1", "F6R040-1" ], "evidence": [ { "id": "48096", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48096" } ] }, { "id": "48100", "name": "", "equation": "L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABZ3NNC5-1", "A6QQV6-1", "F1MQX7-1", "F1MEB9-1" ], "evidence": [ { "id": "48100", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48100" } ] }, { "id": "48104", "name": "", "equation": "N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABZ3NNC5-1" ], "evidence": [ { "id": "48104", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48104" } ] }, { "id": "R-BTA-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABZ3NNC5-1", "Q5E9L5-1" ], "evidence": [ { "id": "R-BTA-5205798", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5205798" } ] }, { "id": "R-BTA-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABZ3NNC5-1" ], "evidence": [ { "id": "R-BTA-5205867", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5205867" } ] }, { "id": "R-BTA-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-BTA-5229015" ], "enzyme_list": [ "A0ABZ3NNC5-1", "Q5E9L5-1" ], "evidence": [ { "id": "R-BTA-5661126", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5661126" } ] }, { "id": "R-BTA-8934735", "name": "PRMT1 arginine-methylates RUNX1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABZ3NNC5-1" ], "evidence": [ { "id": "R-BTA-8934735", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8934735" } ] }, { "id": "R-BTA-8934742", "name": "RUNX1 binds PRMT1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABZ3NNC5-1" ], "evidence": [ { "id": "R-BTA-8934742", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8934742" } ] }, { "id": "R-BTA-8935732", "name": "RUNX1 binds SIN3A,(SIN3B) co-repressor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q32PJ8-1", "A0ABZ3NNC5-1", "Q5E9L5-1" ], "evidence": [ { "id": "R-BTA-8935732", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8935732" } ] }, { "id": "R-BTA-8936481", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKN0-1", "A0ABZ3NNC5-1", "F1N6Y5-1", "A0AAA9TQW6-1", "A0A3Q1MLT2-1", "E1B8D6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-8936481", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8936481" } ] }, { "id": "R-BTA-8936621", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKN0-1", "A0ABZ3NNC5-1", "F1N6Y5-1", "A0AAA9TQW6-1", "A0A3Q1MLT2-1", "E1B8D6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-8936621", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8936621" } ] }, { "id": "R-BTA-8937016", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKN0-1", "A0ABZ3NNC5-1", "F1N6Y5-1", "A0AAA9TQW6-1", "A0A3Q1MLT2-1", "E1B8D6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-8937016", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8937016" } ] }, { "id": "R-BTA-8937050", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKN0-1", "A0ABZ3NNC5-1", "F1N6Y5-1", "A0AAA9TQW6-1", "A0A3Q1MLT2-1", "E1B8D6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-8937050", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8937050" } ] }, { "id": "R-BTA-9023860", "name": "Histone acetyltransferases are recruited to the TFF1 gene", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABZ3NNC5-1", "A0A3Q1M155-1", "A0A3Q1MLT2-1", "E1B8D6-1", "A0A3Q1MWG1-1", "A0A3Q1MIR9-1" ], "evidence": [ { "id": "R-BTA-9023860", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9023860" } ] }, { "id": "R-BTA-9023861", "name": "PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABZ3NNC5-1", "A0A3Q1M155-1" ], "evidence": [ { "id": "R-BTA-9023861", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9023861" } ] }, { "id": "R-BTA-9632182", "name": "PRMT1 methylates ESRs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-5279190" ], "output_participant_list": [], "enzyme_list": [ "A0ABZ3NNC5-1" ], "evidence": [ { "id": "R-BTA-9632182", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9632182" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5279190", "participant_name": "AdoMet [cytoplasm]", "crossref": [ { "id": "59789", "database": "ChEBI", "url": "" }, { "id": "C00019", "database": "COMPOUND", "url": "" }, { "id": "8145813", "database": "PubChem Substance", "url": "" }, { "id": "ZINC000004228231", "database": "ZINC", "url": "" }, { "id": "ZINC000004214738", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-BTA-5229015", "participant_name": "Me2aR4-HIST1H4 [nucleoplasm]", "crossref": [ { "id": "NP_001093194.1", "database": "RefSeq", "url": "" }, { "id": "NP_001361463.1", "database": "RefSeq", "url": "" }, { "id": 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arginine/serine-rich 13A", "type": "synonym", "evidence": [ { "id": "NP_001417724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417724" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJC2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJC2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SRSF10", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJC2", "locus": { "chromosome": "2", "start_pos": 128936367, "end_pos": 128924293, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008072", "url": "https://www.ensembl.org/id/ENSBTAG00000008072" } ] } } ], "crossref": [ { "id": "768310", "url": "https://www.ncbi.nlm.nih.gov/gene/768310", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001417724", "url": 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Isoform 1 of Serine/arginine-rich splicing factor 10 OS=Bos taurus OX=9913 GN=SRSF10 PE=3 SV=1 CANONICAL=A0ABI0NJC2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9U1B4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJC2/entry#A0AAA9U1B4-1", "sequence": { "sequence": "MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYDRRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTSRKI", "length": 183, "header": "tr|A0AAA9U1B4-1|A0ABI0NJC2_BOVIN Computationally mapped isoform of Serine/arginine-rich splicing factor 10 OS=Bos taurus OX=9913 GN=SRSF10 PE=3 SV=2 CANONICAL=A0ABI0NJC2-1" }, "locus": { "chromosome": "2", "start_pos": 128935121, "end_pos": 128924393, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105599.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105599.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103561.2", "url": "https://www.ensembl.org/id/ENSBTAP00000103561.2" } ] } }, { "isoform_ac": "A0ABI0NJC2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJC2/entry#A0ABI0NJC2-1", "sequence": { "sequence": "MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYDRRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH", "length": 262, "header": "tr|A0ABI0NJC2-1|A0ABI0NJC2_BOVIN Isoform 1 of Serine/arginine-rich splicing factor 10 OS=Bos taurus OX=9913 GN=SRSF10 PE=3 SV=1 CANONICAL=A0ABI0NJC2-1" }, "locus": { "chromosome": "2", "start_pos": 128932021, "end_pos": 128924393, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142016.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142016.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104498.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104498.1" } ] } } ], 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NL79-1", "uniprot_ac": "A0ABI0NL79", "uniprot_id": "A0ABI0NL79_BOVIN", "mass": { "chemical_mass": 49875.0, "monoisotopic_mass": 49875.0 }, "refseq": { "ac": "XP_005220976", "name": "RUN domain-containing protein 3A isoform X7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220976" }, "gene_names": [ { "name": "RUNDC3A", "type": "recommended", "evidence": [ { "id": "A0ABI0NL79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL79" } ] }, { "name": "RUNDC3A", "type": "synonym", "evidence": [ { "id": "XP_005220976", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220976" } ] } ], "protein_names": [ { "name": "RUN domain-containing protein 3A", "type": "recommended", "evidence": [ { "id": "A0ABI0NL79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL79/entry#names_and_taxonomy" } ] }, { "name": "RUN domain-containing protein 3A isoform X7", "type": "synonym", "evidence": [ { "id": "XP_005220976", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220976" } ] } ], "function": [ { "annotation": "May act as an effector of RAP2A in neuronal cells.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL79", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL79#function" }, { "database": "UniProtKB", "id": "ARBA00056205", "url": "https://www.uniprot.org/uniprotkb/ARBA00056205#function" }, { "database": "UniProtKB", "id": "A0AAF6YIE8", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YIE8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL79", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL79" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RUNDC3A", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL79", "locus": { "chromosome": "19", "start_pos": 44125625, "end_pos": 44116205, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001615", "url": "https://www.ensembl.org/id/ENSBTAG00000001615" } ] } } ], "crossref": [ { "id": "cd17699", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17699", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614322", "url": "https://www.ncbi.nlm.nih.gov/gene/614322", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46251", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46251", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46251:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46251:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005220976", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220976", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAF6YIE8", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YIE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YIE8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YIE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL79", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL79-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEASFVQTTMALGLSSKKASSRNVAVERRNLITVCRFSVKTLLEKYTTEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMMREEATVLTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQEQLTGLIPGDHAPLAQGSKDLTTRLVNQWPSLGTLSGAEGANNPKLYRRHSFMSTEPLSAEASLSSDSQRLGEGKRDEEPWGPIGKDPTPSMLGLCGSLASIPSCKSLASFKSNECLVSDSPEGSPALSPS", "length": 446, "header": "tr|A0ABI0NL79-1|A0ABI0NL79_BOVIN Isoform 1 of RUN domain-containing protein 3A OS=Bos taurus OX=9913 GN=RUNDC3A PE=3 SV=1 CANONICAL=A0ABI0NL79-1" }, "isoforms": [ { "isoform_ac": "A0AAF6YIE8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL79/entry#A0AAF6YIE8-1", "sequence": { "sequence": "MEASFVQTTMALGLSSKKASSRNVAVERRNLITVCRFSVKTLLEKYTTEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMMREEATVLTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQEQLTGLIPGDHAPLAQGSKDLTTRLVNQWPSLGTLSGAEGANNPKLYRRHSFMSTEPLSAEASLSSDSQRLGEGKRDEEPWGPIGSSETN", "length": 405, "header": "tr|A0AAF6YIE8-1|A0ABI0NL79_BOVIN Computationally mapped isoform of RUN domain-containing protein 3A OS=Bos taurus OX=9913 GN=RUNDC3A PE=3 SV=1 CANONICAL=A0ABI0NL79-1" }, "locus": { "chromosome": "19", "start_pos": 44124621, "end_pos": 44116397, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002119.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002119.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002119.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002119.5" } ] } }, { "isoform_ac": "A0ABI0NL79-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL79/entry#A0ABI0NL79-1", "sequence": { "sequence": "MEASFVQTTMALGLSSKKASSRNVAVERRNLITVCRFSVKTLLEKYTTEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMMREEATVLTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQEQLTGLIPGDHAPLAQGSKDLTTRLVNQWPSLGTLSGAEGANNPKLYRRHSFMSTEPLSAEASLSSDSQRLGEGKRDEEPWGPIGKDPTPSMLGLCGSLASIPSCKSLASFKSNECLVSDSPEGSPALSPS", "length": 446, "header": "tr|A0ABI0NL79-1|A0ABI0NL79_BOVIN Isoform 1 of RUN domain-containing protein 3A OS=Bos taurus OX=9913 GN=RUNDC3A PE=3 SV=1 CANONICAL=A0ABI0NL79-1" }, "locus": { "chromosome": "19", "start_pos": 44125344, "end_pos": 44116397, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147855.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147855.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105719.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105719.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 404, "start_aa": "Thr", "end_pos": 404, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr404", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NL79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL79" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 189, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 404 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NJR5-1", "uniprot_ac": "A0ABI0NJR5", "uniprot_id": "A0ABI0NJR5_BOVIN", "mass": { "chemical_mass": 173304.0, "monoisotopic_mass": 173304.0 }, "refseq": { "ac": "XP_059746615", "name": "neurexin 3 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059746615" }, "gene_names": [ { "name": "NRXN3", "type": "recommended", "evidence": [ { "id": "A0ABI0NJR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ] }, { "name": "NRXN3", "type": "synonym", "evidence": [ { "id": "XP_059746615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059746615" } ] }, { "name": "NRXNIII", "type": "synonym", "evidence": [ { "id": "XP_059746615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059746615" } ] } ], "protein_names": [ { "name": "Neurexin 3", "type": "synonym", "evidence": [ { "id": "A0ABI0NJR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5/entry#names_and_taxonomy" } ] }, { "name": "neurexin 3 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_059746615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059746615" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NRXN3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5", "locus": { "chromosome": "10", "start_pos": 91100452, "end_pos": 89788198, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025324", "url": "https://www.ensembl.org/id/ENSBTAG00000025324" } ] } } ], "crossref": [ { "id": "ENSBTAG00000050101", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000050101", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614412", "url": "https://www.ncbi.nlm.nih.gov/gene/614412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6794361", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6794361", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_059746615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059746615", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAF6Z3W1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z3W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z3W1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z3W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NI80", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NI80-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJR5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPG9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPG9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUI1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUI1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N119", "url": "https://www.uniprot.org/uniprotkb/F1N119", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N119-1", "url": "https://www.uniprot.org/uniprotkb/F1N119-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFTMHSVFFTLKVSLLLGSLLGLCLGLEFMGLPNQWARYLRWDASTRSDLSFQFKTNVSAGLLLYLDDGGVCDFLCLSLVDGRVQLRLSMDCAETAVLSGKRVNDSSWHFVMVSRDRLRTVLVLDGEGRSAELQPQRPYMDVVSDLFLGGVPADIRPSALTLDGVQAMPSFKGLISDLKYGNSEPRLLGSQGVQLDAEGPCGERPCENGGICFLLDGHPTCDCSTTGYGGKLCSEDVSQGPGLSHLMMSEQAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIGDTKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSADGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTDNERFQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTDKSLSTSIFEGGYKAHAPKWESKDFRPNKASETSRTTTTSLSPELIRFTASSSSGMVPKLPAGKMNNRELKPQPDLVLLPLPTAYELDSTKLKSPLITSPMFRNVPTANPTEPGVRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLLKEKPPSSKGGHKKQKNKDKEYYV", "length": 1571, "header": "tr|A0ABI0NJR5-1|A0ABI0NJR5_BOVIN Isoform 1 of Neurexin 3 OS=Bos taurus OX=9913 GN=NRXN3 PE=3 SV=1 CANONICAL=A0ABI0NJR5-1" }, "isoforms": [ { "isoform_ac": "A0AAF6Z3W1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5/entry#A0AAF6Z3W1-1", "sequence": { "sequence": "MHLRIHARRNPPRRPAWTLGIWSLFWGCIVSSVWSSSNVASSSSSPGSHSQHEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTGGELVIPLLVEDPLATPPIATRAPSITLPPTFRPLLTIIETTKDSLSMTSEAGLPCLSDQGSDGCDDDGLVISGYGSGETFDSNLPPTDDEDFYTTFSLVTDKSLSTSIFEGGYKAHAPKWESKDFRPNKASETSRTTTTSLSPELIRFTASSSSGMVPKLPAGKMNNRELKPQPDLVLLPLPTAYELDSTKLKSPLITSPMFRNVPTANPTEPGVRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLLKEKPPSSKGGHKKQKNKDKEYYV", "length": 634, "header": "tr|A0AAF6Z3W1-1|A0ABI0NJR5_BOVIN Computationally mapped isoform of Neurexin 3 OS=Bos taurus OX=9913 GN=NRXN3 PE=3 SV=1 CANONICAL=A0ABI0NJR5-1" }, "locus": { "chromosome": "10", "start_pos": 91099893, "end_pos": 90495258, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022474.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022474.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022474.7", "url": "https://www.ensembl.org/id/ENSBTAP00000022474.7" } ] } }, { "isoform_ac": "A0ABI0NI80-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5/entry#A0ABI0NI80-1", "sequence": { "sequence": "MHLRIHARRNPPRRPAWTLGIWSLFWGCIVSSVWSSSNVASSSSSPGSHSQHEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTDNERFQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTDILLKSFK", "length": 364, "header": "tr|A0ABI0NI80-1|A0ABI0NI80_BOVIN Computationally mapped isoform of Neurexin 3 OS=Bos taurus OX=9913 GN=NRXN3 PE=4 SV=1 CANONICAL=A0ABI0NJR5-1" }, "locus": { "chromosome": "10", "start_pos": 91092342, "end_pos": 90495258, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146658.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146658.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104010.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104010.1" } ] } }, { "isoform_ac": "A0ABI0NJR5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5/entry#A0ABI0NJR5-1", "sequence": { "sequence": "MSFTMHSVFFTLKVSLLLGSLLGLCLGLEFMGLPNQWARYLRWDASTRSDLSFQFKTNVSAGLLLYLDDGGVCDFLCLSLVDGRVQLRLSMDCAETAVLSGKRVNDSSWHFVMVSRDRLRTVLVLDGEGRSAELQPQRPYMDVVSDLFLGGVPADIRPSALTLDGVQAMPSFKGLISDLKYGNSEPRLLGSQGVQLDAEGPCGERPCENGGICFLLDGHPTCDCSTTGYGGKLCSEDVSQGPGLSHLMMSEQAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIGDTKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSADGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTDNERFQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTDKSLSTSIFEGGYKAHAPKWESKDFRPNKASETSRTTTTSLSPELIRFTASSSSGMVPKLPAGKMNNRELKPQPDLVLLPLPTAYELDSTKLKSPLITSPMFRNVPTANPTEPGVRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLLKEKPPSSKGGHKKQKNKDKEYYV", "length": 1571, "header": "tr|A0ABI0NJR5-1|A0ABI0NJR5_BOVIN Isoform 1 of Neurexin 3 OS=Bos taurus OX=9913 GN=NRXN3 PE=3 SV=1 CANONICAL=A0ABI0NJR5-1" }, "locus": { "chromosome": "10", "start_pos": 91099893, "end_pos": 89364821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147853.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147853.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104708.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104708.1" } ] } }, { "isoform_ac": "A0ABI0NPG9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5/entry#A0ABI0NPG9-1", "sequence": { "sequence": "MSFTMHSVFFTLKVSLLLGSLLGLCLGLEFMGLPNQWARYLRWDASTRSDLSFQFKTNVSAGLLLYLDDGGVCDFLCLSLVDGRVQLRLSMDCAETAVLSGKRVNDSSWHFVMVSRDRLRTVLVLDGEGRSAELQPQRPYMDVVSDLFLGGVPADIRPSALTLDGVQAMPSFKGLISDLKYGNSEPRLLGSQGVQLDAEGPCGERPCENGGICFLLDGHPTCDCSTTGYGGKLCSEGLSHLMMSEQGRSKAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIGDTKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLGKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSADGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTDNERFQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTGRLARSSNAARSLRAALTWTWRLTYTFTPIIFISCVVHS", "length": 1392, "header": "tr|A0ABI0NPG9-1|A0ABI0NPG9_BOVIN Computationally mapped isoform of Neurexin 3 OS=Bos taurus OX=9913 GN=NRXN3 PE=4 SV=1 CANONICAL=A0ABI0NJR5-1" }, "locus": { "chromosome": "10", "start_pos": 91091878, "end_pos": 89364821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143691.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143691.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104948.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104948.1" } ] } }, { "isoform_ac": "A0ABI0NUI1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5/entry#A0ABI0NUI1-1", "sequence": { "sequence": "MSFTMHSVFFTLKVSLLLGSLLGLCLGLEFMGLPNQWARYLRWDASTRSDLSFQFKTNVSAGLLLYLDDGGVCDFLCLSLVDGRVQLRLSMDCAETAVLSGKRVNDSSWHFVMVSRDRLRTVLVLDGEGRSAELQPQRPYMDVVSDLFLGGVPADIRPSALTLDGVQAMPSFKGLISDLKYGNSEPRLLGSQGVQLDAEGPCGERPCENGGICFLLDGHPTCDCSTTGYGGKLCSEDVSQGPGLSHLMMSEQGRSKAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIGDTKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSADGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTDNERFQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTANPTEPGVRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLLKEKPPSSKGGHKKQKNKDKEYYV", "length": 1468, "header": "tr|A0ABI0NUI1-1|A0ABI0NUI1_BOVIN Computationally mapped isoform of Neurexin 3 OS=Bos taurus OX=9913 GN=NRXN3 PE=3 SV=1 CANONICAL=A0ABI0NJR5-1" }, "locus": { "chromosome": "10", "start_pos": 91099893, "end_pos": 89364821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144815.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144815.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104852.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104852.1" } ] } }, { "isoform_ac": "F1N119-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5/entry#F1N119-1", "sequence": { "sequence": "MLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIGDTKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSADGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTANPTEPGVRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLLKEKPPSSKGGHKKQKNKDKEYYV", "length": 1061, "header": "tr|F1N119-1|A0ABI0NJR5_BOVIN Computationally mapped isoform of Neurexin 3 OS=Bos taurus OX=9913 GN=NRXN3 PE=3 SV=4 CANONICAL=A0ABI0NJR5-1" }, "locus": { "chromosome": "10", "start_pos": 91099893, "end_pos": 89788198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026956.8", "url": "https://www.ensembl.org/id/ENSBTAT00000026956.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026956.7", "url": "https://www.ensembl.org/id/ENSBTAP00000026956.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6794361", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6794361", "resource": "Reactome", "description": "Neurexins and neuroligins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" }, { "name": "gephyrin clustering involved in postsynaptic density assembly", "id": "GO:0097116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097116", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" }, { "name": "learning", "id": "GO:0007612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007612", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" }, { "name": "adult behavior", "id": "GO:0030534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030534", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" }, { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" }, { "name": "trans-synaptic protein complex", "id": "GO:0098820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098820", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" }, { "name": "neuroligin family protein binding", "id": "GO:0097109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097109", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1189, "end_pos": 1191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1287, "end_pos": 1289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1331, "end_pos": 1333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1544, "end_pos": 1546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 757, "end_pos": 759, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NJR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 198, "end_pos": 235, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NJR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJR5" }, { "id": "PS50025", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50025" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin G", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 202, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 1189, "end_pos": 1191 }, { "start_pos": 1287, "end_pos": 1289 }, { "start_pos": 1331, "end_pos": 1333 }, { "start_pos": 1544, "end_pos": 1546 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 757, "end_pos": 759 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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197582.0, "monoisotopic_mass": 197582.0 }, "refseq": { "ac": "XP_002687369", "name": "AT-rich interactive domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687369" }, "gene_names": [ { "name": "ARID2", "type": "recommended", "evidence": [ { "id": "A0ABI0NLA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6" } ] }, { "name": "ARID2", "type": "synonym", "evidence": [ { "id": "XP_002687369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687369" } ] } ], "protein_names": [ { "name": "AT-rich interactive domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0ABI0NLA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6/entry#names_and_taxonomy" } ] }, { "name": "AT-rich interactive domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_002687369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687369" } ] }, { "name": "BRG1-associated factor 200", "type": "synonym", "evidence": [ { "id": "A0ABI0NLA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein with activation potential", "type": "synonym", "evidence": [ { "id": "A0ABI0NLA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6/entry#names_and_taxonomy" } ] }, { "name": "Zipzap/p200", "type": "synonym", "evidence": [ { "id": "A0ABI0NLA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6#function" }, { "database": "UniProtKB", "id": "ARBA00053694", "url": "https://www.uniprot.org/uniprotkb/ARBA00053694#function" }, { "database": "UniProtKB", "id": "A0ABI0P2G8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARID2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6", "locus": { "chromosome": "5", "start_pos": 34309774, "end_pos": 34405288, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011087", "url": "https://www.ensembl.org/id/ENSBTAG00000011087" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011087", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011087", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16866", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16866", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "517876", "url": "https://www.ncbi.nlm.nih.gov/gene/517876", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:517876", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517876", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR22970", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22970", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22970:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22970:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002687369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687369", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NLA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLA6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV66", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV66-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2G8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2G8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N463", "url": "https://www.uniprot.org/uniprotkb/F1N463", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N463-1", "url": "https://www.uniprot.org/uniprotkb/F1N463-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1834, "header": "tr|A0ABI0NLA6-1|A0ABI0NLA6_BOVIN Isoform 1 of AT-rich interactive domain-containing protein 2 OS=Bos taurus OX=9913 GN=ARID2 PE=4 SV=1 CANONICAL=A0ABI0NLA6-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NLA6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6/entry#A0ABI0NLA6-1", "sequence": { "sequence": "MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGFAKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEDDDEVPPGNPKPQLPIGAIPSSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVCTLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSTVFGEEWKEKTDRDFVKFWKDIVDDNEVRDLISDRNKSHEGTSGEWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEEGNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVTKCLMSRDRFLKMRGMEILGNLCKAEDNGVLICEYVDQDSYREIICHLTLPDVLLVISTLEVLYMLTEMGDVACTKIAKVEKSIDMLVCLVSMDIQMFGPDALAAVKLVEHPSSSHQVLSEIRPQAIEQVQTQTHVASAPASRAVVAQHVAPPPGIVEIDSEKFACQWLNAHFEVNPDCSVSRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDSSNNGQAHIHVVGVKRRAIPLPIQMYYQQQPVSTPVVRVDSVPDVSPSPSPAGIPHGPQTVGNHFQRTPVTNQSSSLTATQMSFPVQGVHTVAQTVSRIPPNPSVHTHQQQNAPVTVIQNKAPIPCEVVKATVIQNSIPQTAVPVSIAVGGGAAQSSVVQNHSTGPQPVTVVNSQMLHHPSVIPQQSPLHTVVPGQIPSGTPVTVIQQAVPQSHIFGRVQNIPACTSTVSQGQQLITTSPQPVQTSSQQTSAGSQPQDTVIIAPPQYVTTSTSNIVSATSVQNFQVATGQMVTIAGVPSPQPSRVGFQNIAPKPLPSQQVSSTVVQQPIQQPQQPTQQSVVIVSQPAQQGQTYAPAIHQIVLANPAALPAGQAVQLTGQPNITPSSSPSPVPPTTNQVPTAMSSSSTPQPQGPPPTVSQMLSVKRQQQQQHSPAPPQQVQVQVQQPQQVQMQVQPQQTNAGVGQPASGESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQVANNQAAGFGVQGQTPAQQLLVGQQNVQLVQSAMPPTGGVQTVPISNLQILPGPLISNSPATIFQGTSGNQVTITVVPNTSFATATVSQGNTTQLIAPAGITMSGTQAGVGLQVQTLPATQASPAGQSSCTTATPPFKGDKIICQKEEEAKEATGLHVHERKIEVMENPSCRRGTTNTSNGDTKENEMQVGSLLNGRKYSDSSLPPSNSGKIQSEANQCSLISNGPSLELGENGASGKQNSEQMDMQDIKSDLKKPLVNGICDFDKGDGSHLSKNIPNHKTSNHVGNGEISPMEPQGTLDATQQDTAKGDQLERTSNGPILTLGVSPSVSSIQEASNVATQQFSGTDLPNGPLASSLNSDVPQQRPSVVVSPHSATSVIQGHQIVAVPHSGSRVSHSPALLSDVRSTNGTAECKTVKRPAEDNDRETVTGIPNKVGVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAVQQKQQHPPTYVQNVVPQNTPMTPSPAVQIQSQPNSSQPSPFSASSQHGDPVRKPGHNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSKDALLAGLKQDEPGQAGNQKSSTKQPAVGGTSSTPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENNLSVLAISNMEASSTLAKCLYELNFTVQSKEQEKDSEMLQ", "length": 1834, "header": "tr|A0ABI0NLA6-1|A0ABI0NLA6_BOVIN Isoform 1 of AT-rich interactive domain-containing protein 2 OS=Bos taurus OX=9913 GN=ARID2 PE=4 SV=1 CANONICAL=A0ABI0NLA6-1" }, "locus": { "chromosome": "5", "start_pos": 34517877, "end_pos": 34310778, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143168.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143168.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105772.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105772.1" } ] } }, { "isoform_ac": "A0ABI0NV66-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6/entry#A0ABI0NV66-1", "sequence": { "sequence": 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"length": 1755, "header": "tr|A0ABI0NV66-1|A0ABI0NV66_BOVIN Computationally mapped isoform of AT-rich interaction domain 2 OS=Bos taurus OX=9913 GN=ARID2 PE=4 SV=1 CANONICAL=A0ABI0NLA6-1" }, "locus": { "chromosome": "5", "start_pos": 34490182, "end_pos": 34310778, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140789.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140789.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104090.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104090.1" } ] } }, { "isoform_ac": "A0ABI0P2G8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6/entry#A0ABI0P2G8-1", "sequence": { "sequence": 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"length": 1758, "header": "tr|F1N463-1|A0ABI0NLA6_BOVIN Computationally mapped isoform of AT-rich interactive domain-containing protein 2 OS=Bos taurus OX=9913 GN=ARID2 PE=4 SV=3 CANONICAL=A0ABI0NLA6-1" }, "locus": { "chromosome": "5", "start_pos": 34405070, "end_pos": 34310778, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014719.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014719.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014719.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014719.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1001, "start_aa": "Thr", "end_pos": 1001, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1001", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1722, "start_aa": "Thr", "end_pos": 1722, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1722", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:517876", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517876", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": 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"start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NLA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLA6" }, { "id": "PS51011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ARID", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 105, "start_aa": "Arg", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": 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"categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3214858", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214858", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9933939", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9933939", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024838260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838260", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHD2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M063", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M063", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M063-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M063-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZ29", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZ29-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCI2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCI2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGJ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRQ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NU16", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NU16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NU16-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NU16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P356", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P356", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P356-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P356-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH8", "url": "https://www.uniprot.org/uniprotkb/E1BNH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSSLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDSQGAVTEGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHEMTKSSLRMRTSSNLAATRLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKTPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPSFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPSEVNLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPVSSVRFVPRDVPLPVVRVASVFANADKADDEKNTDNSEDSRTEDSCNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENL", "length": 1688, "header": "tr|E1BNH8-1|E1BNH8_BOVIN Isoform 1 of Protein polybromo-1 OS=Bos taurus OX=9913 GN=PBRM1 PE=4 SV=3 CANONICAL=E1BNH8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LHD2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH8/entry#A0A3Q1LHD2-1", "sequence": { "sequence": "MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSSLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDSQGAVTEGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHEMTKSSLRMRTSSNLAATRLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKTPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRSTLDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPSFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPSEVNLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPVSSVRFVPRDVPLPVVRVASVFANADKADDEKNTDNSEDSRTEDSCNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENL", "length": 1703, "header": "tr|A0A3Q1LHD2-1|E1BNH8_BOVIN Computationally mapped isoform of Protein polybromo-1 OS=Bos taurus OX=9913 GN=PBRM1 PE=4 SV=1 CANONICAL=E1BNH8-1" }, "locus": { "chromosome": "22", "start_pos": 48280315, "end_pos": 48181593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077324.1", "url": "https://www.ensembl.org/id/ENSBTAT00000077324.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058127.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058127.1" } ] } }, { "isoform_ac": "A0A3Q1M063-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH8/entry#A0A3Q1M063-1", "sequence": { "sequence": "MRRLAFRGAGCALVKLKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSSLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDSQGAVTEGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHEMTKSSLRMRTSSNLAATRLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKTPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPSFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPSEVNLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPVSSVRFVPRDVPLPVVRVASVFANADKADDEKNTDNSEDSRTEDSCNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENL", "length": 1602, "header": "tr|A0A3Q1M063-1|E1BNH8_BOVIN Computationally mapped isoform of Protein polybromo-1 OS=Bos taurus OX=9913 GN=PBRM1 PE=4 SV=2 CANONICAL=E1BNH8-1" }, "locus": { "chromosome": "22", "start_pos": 48280315, "end_pos": 48179939, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071480.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071480.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063331.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063331.2" } ] } }, { "isoform_ac": "A0AAA9RZ29-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH8/entry#A0AAA9RZ29-1", "sequence": { "sequence": "MRRLAFRGAGCALVKLKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSSLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDSQGAVTEGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHEMTKSSLRMRTSSNLAATRLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKTPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPSFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPSEVNLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPVSSVRFVPRDVPLPVVRVASVFANADKADDEKNTDNSEDSRTEDSCNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENL", "length": 1654, "header": "tr|A0AAA9RZ29-1|E1BNH8_BOVIN Computationally mapped isoform of Protein polybromo-1 OS=Bos taurus OX=9913 GN=PBRM1 PE=4 SV=1 CANONICAL=E1BNH8-1" }, "locus": { "chromosome": "22", "start_pos": 48280315, "end_pos": 48179939, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124195.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124195.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075021.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075021.1" } ] } }, { "isoform_ac": "A0AAA9SCI2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH8/entry#A0AAA9SCI2-1", "sequence": { "sequence": "MRRLAFRGAGCALVKLKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSSLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDSQGAVTEGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHEMTKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKTPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPSFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPSEVNLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPVSSVRFVPRDVPLPVVRVASVFANADKADDEKNTDNSEDSRTEDSCNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENL", "length": 1622, "header": "tr|A0AAA9SCI2-1|E1BNH8_BOVIN Computationally mapped isoform of Protein polybromo-1 OS=Bos taurus OX=9913 GN=PBRM1 PE=4 SV=2 CANONICAL=E1BNH8-1" }, "locus": { "chromosome": "22", "start_pos": 48280315, "end_pos": 48179939, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098252.2", "url": "https://www.ensembl.org/id/ENSBTAT00000098252.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081245.2", "url": "https://www.ensembl.org/id/ENSBTAP00000081245.2" } ] } }, { "isoform_ac": "A0AAA9SGJ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH8/entry#A0AAA9SGJ0-1", "sequence": { "sequence": "MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSSLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDSQGAVTEGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHEMTKSSLRMRTSSNLAATRLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKTPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRSTLDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPSFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPSEVNLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPVSSVRFVPRDVPLPVVRVASVFANADKADDEKNTDNSEDSRTEDSCNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENL", "length": 1651, "header": "tr|A0AAA9SGJ0-1|E1BNH8_BOVIN Computationally mapped isoform of Protein polybromo-1 OS=Bos taurus OX=9913 GN=PBRM1 PE=4 SV=1 CANONICAL=E1BNH8-1" }, "locus": { "chromosome": "22", "start_pos": 48280315, "end_pos": 48181593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129023.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129023.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084477.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084477.1" } ] } }, { "isoform_ac": "A0ABI0NRQ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH8/entry#A0ABI0NRQ9-1", "sequence": { "sequence": "MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSSLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDSQGAVTEGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHEMTKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKTPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPSFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPSEVNLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPVSSVRFVPRDVPLPVVRVASVFANADKADDEKNTDNSEDSRTEDSCNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENL", "length": 1656, "header": "tr|A0ABI0NRQ9-1|A0ABI0NRQ9_BOVIN Computationally mapped isoform of Protein polybromo-1 OS=Bos taurus OX=9913 GN=PBRM1 PE=4 SV=1 CANONICAL=E1BNH8-1" }, "locus": { "chromosome": "22", "start_pos": 48280315, "end_pos": 48181593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148000.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148000.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105463.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105463.1" } ] } }, { "isoform_ac": "A0ABI0NU16-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH8/entry#A0ABI0NU16-1", "sequence": { "sequence": "MRRLAFRGAGCALVKLKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSSLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDSQGAVTEGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHEMTKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKTPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPSFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPSEVNLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPVSSVRFVPRDVPLPVVRVASVFANADKADDEKNTDNSEDSRTEDSCNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENL", "length": 1621, "header": "tr|A0ABI0NU16-1|A0ABI0NU16_BOVIN Computationally mapped isoform of Protein polybromo-1 OS=Bos taurus OX=9913 GN=PBRM1 PE=4 SV=1 CANONICAL=E1BNH8-1" }, "locus": { "chromosome": "22", "start_pos": 48280315, "end_pos": 48179939, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148775.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148775.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107197.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107197.1" } ] } }, { "isoform_ac": "A0ABI0P356-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH8/entry#A0ABI0P356-1", "sequence": { "sequence": "MLIRDPRKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSSLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDSQGAVTEGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHEMTKSSLRMRTSSNLAATRLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKTPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPSFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPSEVNLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPVSSVRFVPRDVPLPVVRVASVFANADKADDEKNTDNSEDSRTEDSCNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENL", "length": 1700, "header": "tr|A0ABI0P356-1|A0ABI0P356_BOVIN Computationally mapped isoform of Protein polybromo-1 OS=Bos taurus OX=9913 GN=PBRM1 PE=4 SV=1 CANONICAL=E1BNH8-1" }, "locus": { "chromosome": "22", "start_pos": 48280315, "end_pos": 48180530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146358.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146358.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106015.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106015.1" } ] } }, { "isoform_ac": "E1BNH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH8/entry#E1BNH8-1", "sequence": { "sequence": "MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSSLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDSQGAVTEGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHEMTKSSLRMRTSSNLAATRLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKTPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPSFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPSEVNLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPVSSVRFVPRDVPLPVVRVASVFANADKADDEKNTDNSEDSRTEDSCNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENL", "length": 1688, "header": "tr|E1BNH8-1|E1BNH8_BOVIN Isoform 1 of Protein polybromo-1 OS=Bos taurus OX=9913 GN=PBRM1 PE=4 SV=3 CANONICAL=E1BNH8-1" }, "locus": { "chromosome": "22", "start_pos": 48280315, "end_pos": 48181593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019672.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019672.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019672.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019672.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1470, "start_aa": "Thr", "end_pos": 1470, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1470", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:506557", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506557", "resource": "KEGG Pathway" }, { "id": "R-BTA-3214858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214858", "resource": "Reactome", "description": "RMTs methylate histone arginines" }, { "id": "R-BTA-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" }, { "id": "R-BTA-9933939", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9933939", "resource": "Reactome", "description": "Formation of the polybromo-BAF (pBAF) complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZMW9-1", "protein_name": "Protein polybromo-1", "gene_name": "Pbrm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSSLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDINLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTMADGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMTKSSLRIRTATNLAAARLTGPSHNKSSLDEERNPTSKCYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPSRPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTTGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPETFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDEEKSTDNSDDNRAEDSFNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDTEEMGEEDSEVIEPPSLPQLQTPLANELDLMPYTPPQSTPKSAKGSAKKESSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKAAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVTPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPTGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1705 }, "evidence": [ { "id": "E1BNH8", "url": "https://omabrowser.org/oma/group/E1BNH8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F8D8-1", "protein_name": "Protein polybromo-1", "gene_name": "pbrm1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMGSKRRRATSPSSSVSGGDFEDSQSTSISSTSRKRRRIANIPTVDPIAVCHELYNTIRDYKDDQGRMLCELFIRAPKRRNQPDYYDVVSQPIDMMKIQQKLKMEEYDDVEQLTSDFQLLFSNAKTYYKPETPEYRAACKLWDLYIRTKNEFVQRGDYDEDDDDDDPQENLGGATEEESMSSLKEVLGMLLDAVLTYTEHGRLISELFQRLPSKMQYPDYYAIIKEPIDLKSIAHRIQMCYYKSVNHMAKDIDLLVKNAKTYNEPGSQVFKDANTIKKVFAQKKLELEHSEPIKCSIRIRNRRFAHGDRLSCITTALQYGSESEEDAILTGSVHYDEVESEAESIHSSMDVSNPIFQMYEAVRGVRNSQGQLLAEPFFQLPSRKDYPDYFQQISHPVSLQQIRSKMKNNEYESVEQIDTDLNRMFENAKRYNVPSSQIYKRVLKLQHILQMKRKELTRRDDEDGDSRLSSTLSDGGSTKRKSHKKNTKKNRMKALLAAVAETREMGTGRRLCDLFMVKPSKKDYPDYYKIILEPMDMRIIEHNIRSDKYPNEDSMMEDMKLMFRNARHYNEEGSRVYNDANILEKILREKRKELGPPPDDDEIVSPKLKIRKSGISPKKSKYLTPLQQKLNELYEAVKNYTDKRGRRLSTIFLRLPSRAELPDYYVAIKKPIDMEKIKSHMLANKYQDVDALVEDLVLMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGGDDAHVPDVARLIQELVRNLFVSVLGHQDDEGRCYSDSLAEIPAVDPNCSDKTPLNFEIIRANVDKGRYRRLDVFQDQMFEVLEKARRLHRTDSEIFEDSVELQQFFIRIRDELCKNGEILLTPALSYTIKHLHSDVEKEKKEKLPKEYEEDKLKREEEKKEAEKSEDTAGGGWQGALQRNYSQDCSFKDNMYHVGDYVYVEPTEPNLQPHIVCIERLWQDDAGENWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKIPVSKILGKCVVMFVKEYFKLQPDSFRPEDVFVCESRYSAKTKSFKKIKMWTMPLSSVKFVPREVPLPVVRVASMFAPKQESEKPPEVTEDDKALPSVIDKEKEDITLEVNNGEPGCQYYEQLCYNNIWLKVGDCVYIRSHGLVRNRVGRIEKMWVRDGAAYFFGPIFIHPEETEHEPTKMFYKKEVFLSNLEESCPMTCIGGKCTVSSFKDFLSCRPTEMPEEDVLLCESRYIESEKQMKKFKGLKRFSLSAKVVEDEIYYFRKLIVPQKEPSPLLEKKIEELEAKFADMTDEELDDLGDDDGDGSDAHCMPQLQTQLSGDMDMLHYAPQQSVPKSIKGLSKKEGAKRKINMSGYILFSSEMRAVIKAQHPDFSFGELSRLVGTEWRNLEATKKAEYEERAAKVAEQQERDRAHQGSPRAGTPAGLLMGVVPLPTPMGLVPMAGMLGSFRPPMFTCQGPGMINMPPHPMGLPALPLNFPWGLPGMPFHGMNGMAPGSTGSAYGTQMGGMNSGQQVPPPYPGQGQVGQPAHQQPSTPMFVAPPPKPQRLLHSEAYLKYIEGLSAESTTVSKWDQTLSARRKDVRLTKEQESRLPSHWLKSKGAHKTMADALWRLRDLMLRDTLNIQHTYNIHNI", "length": 1627 }, "evidence": [ { "id": "E1BNH8", "url": "https://omabrowser.org/oma/group/E1BNH8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86U86-1", "protein_name": "Protein polybromo-1", "gene_name": "PBRM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1689 }, "evidence": [ { "id": "E1BNH8", "url": "https://omabrowser.org/oma/group/E1BNH8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BSQ9-1", "protein_name": "Protein polybromo-1", "gene_name": "Pbrm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTLADGSSPGYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMTKSSLRIRTASNLAAARLTGPSHNKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNHQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKLSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNSPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTTGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSDDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLRYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEAPSLPQLQTPLANELDLMPYTPPQSTPKSAKGSAKKESSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1634 }, "evidence": [ { "id": "E1BNH8", "url": "https://omabrowser.org/oma/group/E1BNH8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VC36-1", "protein_name": "Polybromo", "gene_name": "polybromo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSRKRRASSISSRQDEDPLQLDDSTPEQSPVQQTTTQSARKKRRLDPTELCQQLYDSIRNIKKEDGSMLCDTFIRVPKRRQEPSYYDVVVNPIDLLKVQQKLKTDSYDDLDDLMADLELLIGNAKAFYIPGSSEHQDAVSLWQHIHSQRQRIMEANGLAEEEPRARRMSRQVRRMTSSTEPGGDGATDDEYNQYEELFASVMTATDPVGDRLMHRMFQLLPSKKIYPDYYDVIEHPIDLRLIATKIQMNAYSSLAEMERDLLQMTKNACLFNEPGSQIYKDAKSLKRIFTQRRIELEMGKGKLAKRVKSLSSAAIAALKEEVDSSDDEETSKKGEGPMWALFDHLYNAPGTSEHPGVTGPPLGNSLWKLPVRRFHPEYFELIKRPISMSQIHTKLKKGDYANISDLTADLYLMLDNAKKAFPTSHRTHKDALKMLKLMNAKLVEESLEEGSDLDDEDAEEMDTEVFTVSTQPEKRKPGRPRINSNSNSNASHTPNNSNSPKSNRIAINAAIKKKILSIQKYLVDYSLGNRRPIEMFMEKPPRKIYPDYYDIIQNPIDMNTIEHNIRTDRYAAVEDVVSDYRLMFSNCRQYNEEGSNIYEDANILERALNEKLKEFPGLTEGKKSQQKYSKVGRKLKTAVITERLWQFYETVKEYQEPKGKRQLSLIFTKLPSKSEYPDYYDIIREPIDMDRIAQKLKQGAYDTLDDLAADFLLMLENACKYNEPDSQIYKDALVLQQLTLQLKQQLRTERDSLPDVPLAVQELFLTLFTTIYNHQDEEGRCYSDSLAELPEYDEIGEGPKVRGISLDLVKRRLDKGAYKRLDVYQEDIFACLERARKLSRTDSDIFQDSIELQTYFIRKRDELCKDTLSSSALNFSLERLMADVELCRQQKMQQEEQDQEQDKEKDEFNAAKGESMTINQQVFSPGDYVYVQMPENKIPSICCIERLWTSPTNEKLMQASIFVRPHETYHVTTRKFLEKEVFKSSLSQTISMDKVQGMCYVMNIKDYIKMRPENLPEKDVYVCESRYNIQGRWFKKLKSWPPVREGSSVKFVPREQPLELKRVMSVFKERLEKHKGELEELKLQETLVEKEKPNVSCDPPPNAEVGSTYYQQYNTICSGAIKTGDFVYVATQTGKQSVAQVQQIWEQNGKSYFKGPWLLPPSETTPGLGKQFYRQELLLSTVEEVSPVVGIVGRCAVLEYSEFISSRPTEISESDVYICESVYDELKKALRKLVTGNMRKFQHSPSVTEDEIFYFKTPIKPSKDFKNELNELGMLEDSMDGDTPSLSSDIAAMSSPAPSVNSTPLTSKVKAAKSAKKCLTGYILYSSEVRKSICQSNPDATFGDISRMVGTEWKNLPSSVKQSWEDRASRQNEETAALRRELDDVQNSASPSSQVSQDVFGQVLTFECQWDKCDFQFEELSDCTEHCMSDSTGHIQRHPQAGVETEYVCLWRNCPRVKKSVQAFPNVLRLIKHVREVHLSKCGKTISAADRSKNFVPRRQKHAQLATTVPIPPSLAQSPRAPSNLEAVQLQQQQHPQQNMHQLQQQQTIVLGPPPEPLFVTVPPRTTRVIHSEAYIKYIESLQTGSHLNVVTCNNNWRRALTHITPAQVVAKTALPEKWIGPNLRDQGNVVQALCHLRNFMVDDILQIRRSCN", "length": 1654 }, "evidence": [ { "id": "E1BNH8", "url": "https://omabrowser.org/oma/group/E1BNH8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BNH8", "url": "https://www.uniprot.org/uniprotkb/E1BNH8" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E1BNH8", "url": "https://www.uniprot.org/uniprotkb/E1BNH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "E1BNH8", "url": "https://www.uniprot.org/uniprotkb/E1BNH8" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "E1BNH8", "url": "https://www.uniprot.org/uniprotkb/E1BNH8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BNH8", "url": "https://www.uniprot.org/uniprotkb/E1BNH8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "E1BNH8", "url": "https://www.uniprot.org/uniprotkb/E1BNH8" } ], "pmid": "" }, { "name": "RSC-type complex", "id": "GO:0016586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016586", "evidence": [ { "database": "UniProtKB", "id": "E1BNH8", "url": "https://www.uniprot.org/uniprotkb/E1BNH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1001, "end_pos": 1003, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1261, "end_pos": 1263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1381, "end_pos": 1383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 670, "end_pos": 672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" }, { "start_pos": 854, "end_pos": 856, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH8" }, { "id": "PS51038", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51038" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAH", "eco_id": "ECO_0000259", "start_pos": 955, "end_pos": 1073, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH8" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 134, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH8" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 1378, "end_pos": 1446, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1470 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1001, "end_pos": 1003 }, { "start_pos": 1261, "end_pos": 1263 }, { "start_pos": 1381, "end_pos": 1383 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 670, "end_pos": 672 }, { "start_pos": 772, "end_pos": 774 }, { "start_pos": 854, "end_pos": 856 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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{ "id": "PTHR45796", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45796", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45796:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45796:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192453", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192453", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNC5-1", 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"MMVESASETIRSAPSGQNGVGSLSGQADGGGGGSSGGGAAGPAAGGAGRDSAVGADSNGEMSPAELLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQILSPPQLQALLQQQQALMIQQLQEYYKKQQEQLHLQLLTQQQAGKQQPKEALGNKQLAFQQQLLQMQQLQQQHLLNLQRQGLVSLQPSQASGPLQTLPQAAVCPTDLPQLWKGEGAPGQPAEDSVKQEGLDLTGTATTATSFAAPPKVSPPLSHHTLPNGQPTVLTPRRDSSSHEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQAMMTHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLAHPPTSAAAPVTPLRPPGLGSASLHSGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYGTLNASYQAALAESSFPLLNSPGMLNPGSASSLLPLGHDDAGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRRPGPPMGPPNPSTAGPPEDRDLEEELPGEELS", "length": 685, "header": "tr|E1BM52-1|E1BM52_BOVIN Isoform 1 of Forkhead box P4 OS=Bos taurus OX=9913 GN=FOXP4 PE=4 SV=3 CANONICAL=E1BM52-1" }, "locus": { "chromosome": "23", "start_pos": 15415694, "end_pos": 15384042, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018905.7", "url": "https://www.ensembl.org/id/ENSBTAT00000018905.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018905.6", "url": "https://www.ensembl.org/id/ENSBTAP00000018905.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:517805", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517805", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BM52", "url": "https://www.uniprot.org/uniprotkb/E1BM52" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BM52", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BM52", "url": "https://www.uniprot.org/uniprotkb/E1BM52" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BM52", "url": "https://www.uniprot.org/uniprotkb/E1BM52" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BM52", "url": "https://www.uniprot.org/uniprotkb/E1BM52" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BM52", "url": "https://www.uniprot.org/uniprotkb/E1BM52" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": 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"end_pos": 625 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLP2-1", "uniprot_ac": "E1BLP2", "uniprot_id": "E1BLP2_BOVIN", "mass": { "chemical_mass": 96184.0, "monoisotopic_mass": 96184.0 }, "refseq": { "ac": "NP_001193215", "name": "solute carrier family 12 member 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193215" }, "gene_names": [ { "name": "SLC12A9", "type": "recommended", "evidence": [ { "id": "E1BLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" } ] }, { "name": "SLC12A9", "type": "synonym", "evidence": [ { "id": "NP_001193215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193215" } ] } ], "protein_names": [ { "name": "Solute carrier family 12 member 9", "type": "recommended", "evidence": [ { "id": "E1BLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLP2/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 12 (potassium/chloride transporters), member 9", "type": "synonym", "evidence": [ { "id": "NP_001193215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193215" } ] }, { "name": "solute carrier family 12 member 9", "type": "synonym", "evidence": [ { "id": "NP_001193215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193215" } ] } ], "function": [ { "annotation": "May be an inhibitor of SLC12A1. Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function. May play a role in lysosomal ion flux and osmoregulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU9#function" }, { "database": "UniProtKB", "id": "ARBA00055457", "url": "https://www.uniprot.org/uniprotkb/ARBA00055457#function" }, { "database": "UniProtKB", "id": "E1BLP2", "url": "https://www.uniprot.org/uniprotkb/E1BLP2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLP2", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC12A9", "url": "https://www.uniprot.org/uniprotkb/E1BLP2", "locus": { "chromosome": "25", "start_pos": 35789615, "end_pos": 35799164, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001131", "url": "https://www.ensembl.org/id/ENSBTAG00000001131" } ] } } ], "crossref": [ { "id": "E1BLP2", "url": "https://alphafold.ebi.ac.uk/entry/E1BLP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001131", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001131", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617865", "url": "https://www.ncbi.nlm.nih.gov/gene/617865", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617865", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617865", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NIKYWRP", "url": "https://omabrowser.org/oma/group/NIKYWRP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LNU9", "url": "https://www.orthodb.org/?gene=A0A3Q1LNU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BLP2", "url": "https://www.orthodb.org/?gene=E1BLP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11827:SF98", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11827:SF98", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193215", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193215", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLP2", "url": "https://www.uniprot.org/uniprotkb/E1BLP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLP2-1", "url": "https://www.uniprot.org/uniprotkb/E1BLP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASENSPLLAYRLLGEEGVSFPANGAGGPGGAPARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVEAILDVFGADASGSSGLRVLPQGYGWSLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRDIPLAPRPGPNGSSLPPQVGHFTGFNSSTLKANLDAGYAKDYTTGAMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIVAVAYTFFIYILLFFLSSFTCDRVLLQEDYGFFRAISLWPPLVLVGIYATSLSASMSSLIGASRILHALAQDDLFGVILAPAKVVSRGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFNLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDRAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAAPQDHFLTDPAFSEPADGTQEAGAPALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLSRGSGGTSQPHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILGMVPAWHSARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVREVVWGEGAASEEPEEEEEGDFVNGRRGDAEAEALACSANALVRAQQGRGRGGPGGPEEGDGEVGPATALTFLYLPRPPADSARYLRYLGLLEILSRDLGPTLLIHGVTPVTCTDL", "length": 914, "header": "tr|E1BLP2-1|E1BLP2_BOVIN Isoform 1 of Solute carrier family 12 member 9 OS=Bos taurus OX=9913 GN=SLC12A9 PE=3 SV=1 CANONICAL=E1BLP2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNU9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLP2/entry#A0A3Q1LNU9-1", "sequence": { "sequence": "MGKGWPQELGGAFLPSPETWSLPLVGQWPGSACPPPPLTLGVAGFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVEAILDVFGADASGSSGLRVLPQGYGWSLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRDIPLAPRPGPNGSSLPPQVGHFTGFNSSTLKANLDAGYAKDYTTGAMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIVAVAYTFFIYILLFFLSSFTCDRVLLQEDYGFFRAISLWPPLVLVGIYATSLSASMSSLIGASRILHALAQDDLFGVILAPAKVVSRGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFNLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDRAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAAPQDHFLTDPAFSEPADGTQEAGAPALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLSRGSGGTSQPHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILGMVPAWHSARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVREVVWGEGAASEEPEEEEEGDFVNGRRGDAEAEALACSANALVRAQQGRGRGGPGGPEEGDGEVGPATALTFLYLPRPPADSARYLRYLGLLEILSRDLGPTLLIHGVTPVTCTDL", "length": 897, "header": "tr|A0A3Q1LNU9-1|E1BLP2_BOVIN Computationally mapped isoform of Solute carrier family 12 member 9 OS=Bos taurus OX=9913 GN=SLC12A9 PE=3 SV=2 CANONICAL=E1BLP2-1" }, "locus": { "chromosome": "25", "start_pos": 35798550, "end_pos": 35790010, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068562.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068562.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058684.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058684.2" } ] } }, { "isoform_ac": "E1BLP2-1", "url": "https://www.uniprot.org/uniprotkb/E1BLP2/entry#E1BLP2-1", "sequence": { "sequence": "MASENSPLLAYRLLGEEGVSFPANGAGGPGGAPARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVEAILDVFGADASGSSGLRVLPQGYGWSLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRDIPLAPRPGPNGSSLPPQVGHFTGFNSSTLKANLDAGYAKDYTTGAMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIVAVAYTFFIYILLFFLSSFTCDRVLLQEDYGFFRAISLWPPLVLVGIYATSLSASMSSLIGASRILHALAQDDLFGVILAPAKVVSRGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFNLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDRAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAAPQDHFLTDPAFSEPADGTQEAGAPALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLSRGSGGTSQPHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILGMVPAWHSARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVREVVWGEGAASEEPEEEEEGDFVNGRRGDAEAEALACSANALVRAQQGRGRGGPGGPEEGDGEVGPATALTFLYLPRPPADSARYLRYLGLLEILSRDLGPTLLIHGVTPVTCTDL", "length": 914, "header": "tr|E1BLP2-1|E1BLP2_BOVIN Isoform 1 of Solute carrier family 12 member 9 OS=Bos taurus OX=9913 GN=SLC12A9 PE=3 SV=1 CANONICAL=E1BLP2-1" }, "locus": { "chromosome": "25", "start_pos": 35798261, "end_pos": 35790010, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004493.6", "url": "https://www.ensembl.org/id/ENSBTAT00000004493.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004493.4", "url": "https://www.ensembl.org/id/ENSBTAP00000004493.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617865", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617865", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2BFP5-1", "protein_name": "Solute carrier family 12 member 9", "gene_name": "slc12a9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANEHSPLLVHGVYSMMGNAEDSRGGSAGTGEASNPKTDPRKLNTFFGVMVPTILSMFSIVLFLRTGFVVGHAGLLHGLLMLFVAYFIISLTILSICAISTNGAVEGGGAYFMISRSLGPEFGGSIGLMFYLAKVCACGVYVLGLVEAIMDVFGQDPGSSVAQGLRVLPQGYWYTVLYSSVVLLLCMLVCLVGAHIYAKASFLILLVVTVSLISIIISPLIVSPQGFNITHTYGNNHSVTVSPSYTGFNSTTLKNNLGPRYSLDYSTNTMMSFATVFAVMFTSCTGIMAGANMSGELKNPSESIPKGTIMAVAYTFTVYVLLYLLLSSTCDRSLLLNDYAVFQRVNVWPPFVTIGVYCASLSAAMCSMIGASRILHALALDQLFGLPLAPAAVTSSSGNPWVSVLYTWALVQCTLFAGQLNVIAGIVTVFYLLAYAAVDLACLALEWASAPNFRPTFQFFSWHTCLLGIISCVVMMFVINPVYSSASIVLLLLLLLFLHYRSPTSSWGYISQALIFHQVRKYLLMLDSRKDHVKFWRPQVLLMVSNPRSSCQLICFVNQLKKGGLFVLGHVQIGDLDVLPADPVQPQYNFWLSLVDKLGVKAFVDLTLSPSVRQGTQHLLRITGLGGMKPNTLVLGFYDNSYPEDYFLQDPVFCKGDRSEGDNFGVDLPSLQAHFPPVRHAESPRALQPQEYVSIIQDAIKMGKNICLARYFFQLPPESKGATYMWGKDSMDTIDVWPTNLLTPGSASYADVGSLFLLQMACVLNMASGWRRARLRIFVCVESESEDQGWLAKEEQFRELLGKLRIRAAIKIVAWDNVARMVRGPNTESQPVSEDFLCAVNGLLKEHSSTAAVRFLYLPDPPSSCELSQQYLTQLDTLTRDLGPTLLIHGVTPVTCTEL", "length": 899 }, "evidence": [ { "id": "E1BLP2", "url": "https://omabrowser.org/oma/group/E1BLP2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LUK0-1", "protein_name": "Solute carrier family 12 member 9", "gene_name": "SLC12A9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASENSPLLAYRLLGEEGVAFPANGTGGPGGASARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYFILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVEAILDVFGADAAGSSGLRVLPQGYGWSLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRDIPLTPRPGPNGSSLPPQVGHFTGFNSSTLKANLGAGYAKDYTTGAVMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTITAVAYTFFIYILLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATSLSASMSSLIGASRILHALAQDDLFGVILSPAKVVSRGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARVGPSSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPLYGAWLSLVDRAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAAPQDHFLTDPAFSEPADATQEGGSPALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLSRGSGGTSQPHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILGMVPAWHTARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVQEVVWGEGAGSEEPEEEEEGDFVNGRRGDAEAEALARSANALVRAQQGRGRGGGPGGPEGGDGEEGPTTALTFLYLPRPPADPSRYPRYLALLEILSHDLGPTLLIHGITPVTCTDL", "length": 915 }, "evidence": [ { "id": "E1BLP2", "url": "https://omabrowser.org/oma/group/E1BLP2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P38329-1", "protein_name": "Vacuolar cation-chloride cotransporter 1", "gene_name": "VHC1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVSRFYQIPGTHRPSSAISSSNESSSLLSARRISQTYFNYQATPECQKVSSKYDPDNPNKDKLGTYDGVFVPTALNVLSILMFLRFGFILGQLGIICTIGLLLLSYTINLLTTLSISAISTNGTVRGGGAYYMISRSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIEPLLYNLGYSAQGEPPAALGELLPRGHWHEFTYATVILFLCFSVAFVGSQTVSRAGNILFLVLAASIFSIPLSALIRSPFTEGGISYTGPSWQTFHDNLLPHLTKGAAGSLLKGKETFNDLFGVFFPATAGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPRRSLYDEVQIIQTISSVQWVIFMGEMATSLFSIIVGMLGAAYVLEAIAKDNIIPGLEIFAHSPLYSLIFTWILTQLCLFSDVNKIATFITMTFLMTFVVMNLACFLLGISSAPNFRPSFKYFNRYTTAIGALLSVVAMLIVDGISASVLFLAMILLFLFIHYFSPPKSWGDVSQSLIYHQVRKYLLRLRQDNIKYWRPQILLFVDNPRTSWNLIRFCNHLKKGGLYILGHVAVTADFPKQLNELKTQQKAWMKIRDMAAIKAFVQVGTGPSLIWGIRNVFIGSGLGGMKPNITVVGFFDLESYRKHIPQSRSQNNLQKQVEIKATVPRSTCSDVKINVPLPTDECKNETKVNVQQWVQIVEDLSLMQSNIAIAHGFKNLEIPNKRDSCFPKKTIDLYPIQMCGKVEAKGDQPAAITTNFDTYTLILQLAAILVTVPEWKRTHSLRVILFVEQEYHRTNETQRMKKLLQVLRIDAEVLVVSLDQFRVYNTIVKGDPIVFDYVNSKLADNEWWKDLVEARDTLKPKRRFSTIEPQTIAKQFTQSRKYTSGVQKLGVSFTMNTRMPTNRIDTPCESEDSDLDTDLTSIRDAFSASTNISVGKDLTTKSKTGSDRTNLLVKNLQSDVSTQSLRPVFSSNTLPRTRVVEDGTGEQPTLIPIAEPDLSNGNGTGSGIGNGNKLKKPVLPELSPCCSKDSLVTAMQNLGFNDLPSTAQHLVLNDVMTQMSKSSDLIFSTLPVPALGTHEDHDASLQYVEDLDIWLEGLPPCMLINSQTMTVTTAL", "length": 1120 }, "evidence": [ { "id": "E1BLP2", "url": "https://omabrowser.org/oma/group/E1BLP2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q66HR0-1", "protein_name": "Solute carrier family 12 member 9", "gene_name": "Slc12a9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASENSPLLAYRLLGEEGAAFPPNGAGGSGVASARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESILDVFGADVTGSSGIKVLPQGYGWNLLYGSLLLGLVGGVCALGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRNITLAPRPGTNGSSVPPRHGHFTGFNGSTLKDNLGAGYAEDYTTGAMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRALLQGDYGFFRDISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPAEGTREGGSPALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLSRGSGSSAQLHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILSMVPAWHSARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVQEVVWGEGAEAGEPEEEEGDFVNGGRGDEEAEALACSANALVRAQQGRGTGGGPGGPEGRDGEEGPTTALTFLYLPRPPADPARYPRYLALLETLSRDLGPTLLIHGVTPVTCTDL", "length": 914 }, "evidence": [ { "id": "E1BLP2", "url": "https://omabrowser.org/oma/group/E1BLP2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99MR3-1", "protein_name": "Solute carrier family 12 member 9", "gene_name": "Slc12a9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASESSPLLAYRLLGEEGAAFPPNGAGVSGVPSSRKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYIILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESILDVFGADATGSSGIQVLPQGYGWNLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRNIPLAPRPGTNASSVPHRHGHFTGFNGSTLRDNLGAGYAEDYTTGAMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRALLQEDYGFFRDISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPAEGTREGGSPALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLSRGSSSSAQLHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILSMVPAWHSARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVQEVVWGEGAETGEPEEEEGDFVNGGRGDEEAEALACSANALVRAQQGRGTVGGPGGPEGRDGEEGPTTALTFLYLPRPPADPARYPRYLALLETLSRDLGPTLLIHGVTPVTCTDL", "length": 914 }, "evidence": [ { "id": "E1BLP2", "url": "https://omabrowser.org/oma/group/E1BLP2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXP2-1", "protein_name": "Solute carrier family 12 member 9", "gene_name": "SLC12A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASESSPLLAYRLLGEEGVALPANGAGGPGGASARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYFILALTVLSVCAIATNGAVQGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESVLDVFGADATGPSGLRVLPQGYGWNLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLISFVAVGPRDIRLTPRPGPNGSSLPPRFGHFTGFNSSTLKDNLGAGYAEDYTTGAVMNFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIVAVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIGASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLAALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDRAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPADSTREGSSPALSTLFPPPRAPGSPRALNPQDYVATVADALKMNKNVVLARASGALPPERLSRGSGGTSQLHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILGMVPAWHSARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVQEVVWGEGAGAGEPEAEEEGDFVNSGRGDAEAEALARSANALVRAQQGRGTGGGPGGPEGGDAEGPITALTFLYLPRPPADPARYPRYLALLETLTRDLGPTLLVHGVTPVTCTDL", "length": 914 }, "evidence": [ { "id": "E1BLP2", "url": "https://omabrowser.org/oma/group/E1BLP2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VJ75-1", "protein_name": "Solute carrier family 12 member 9", "gene_name": "Dmel\\CG10413", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSASAEQETAPIANSRSGRTGSVFRSFGSLFGGSQNSGDRPHTPQDGDGYVEFGMQDPDRSGRTLGTFAGVFSPVALSMFSALVFIRVGYIVGNAGLYVTLLQFLIAYGILLFTVASVCAISTNGAIEGGGVYFMISRTLGLEFGGSIGTLFFFANVVGSAMAISGCTEGIMDNFGPRGHFVSGDSHLPDGDWWRFLTSSMINTLQLLVCLVGAALFAKTSVIILATVTVCLFATYFSFLFVGATNNTIPVPGDNILSNTTTFLDYTGLNATTLRDNLGSHYGRDYTSNGKQVDFSTTFGVLFSGVTGIMAGANMSGELKNPSKSIPYGTLSAVAFTFVSYIILSFLMSCTTPYFTMQNNYLFLMPVNLWPPFTAIGILTATFSTSLSNLIGSSRILEALSKDQVFGSLLNFVIHGTWKGNPIAAVAVSWCLVECILLIGSFNIIAQINSVLFMLSYLATNLACLGIELTGAPNFRPLFKFFTWHTCLVGLLGTLIMMFVINFIYASSCIILCLILVIALHLFSPATQAAQWGSISQALMFHQVRKYLLMLDPRKDHVKFWRPQILLLVSSPRSCCPLVDFVNDLKKSGLYIIGHVKLGDFKGIEDAEDNQQWWSFLDHMRVKAFTEVTLSRSIREGVQHLIRLSGIGAMKPNTIILGFYDSEAPRDFFQNGSSPYKTDDFNNGEIQNFPIRRDGDPKQFQIQEYVQILCDTLRMKKNLCLCRNFQRLDKNFISMSKHVKYIDVWPINIFNPTSGDPFDMVSLFMMQLAVIMLAKWKHLRVRIFLCEANDERTVGTFDTQTPQMEIFSKMKLEQSLKELRITADIVEIQEWSRDTDFSRHARTLKQFTAQADNVVLEDDDEVGEETLNRSLLYMQRANQIIRERSDQTALSFIYLAAPPKLSAPDFAQRSASYMELLTELTADLPPTILVHGVSTVTSTTL", "length": 941 }, "evidence": [ { "id": "E1BLP2", "url": "https://omabrowser.org/oma/group/E1BLP2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BLP2", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "E1BLP2", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chloride:monoatomic cation symporter activity", "id": "GO:0015377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015377", "evidence": [ { "database": "UniProtKB", "id": "E1BLP2", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" } ], "pmid": "" }, { "name": "potassium:chloride symporter activity", "id": "GO:0015379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015379", "evidence": [ { "database": "UniProtKB", "id": "E1BLP2", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell volume homeostasis", "id": "GO:0006884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006884", "evidence": [ { "database": "UniProtKB", "id": "E1BLP2", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" } ], "pmid": "" }, { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "E1BLP2", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" } ], "pmid": "" }, { "name": "potassium ion homeostasis", "id": "GO:0055075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055075", "evidence": [ { "database": "UniProtKB", "id": "E1BLP2", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" } ], "pmid": "" }, { "name": "chloride ion homeostasis", "id": "GO:0055064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055064", "evidence": [ { "database": "UniProtKB", "id": "E1BLP2", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLP2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 914, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLP2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLP2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" }, { "id": "PF00324", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00324" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amino acid permease/ SLC12A", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 535, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLP2" }, { "id": "PF03522", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03522" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SLC12A transporter C-terminal", "eco_id": "ECO_0000259", "start_pos": 547, "end_pos": 634, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 286, "end_pos": 288 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLQ5-1", "uniprot_ac": "E1BLQ5", "uniprot_id": "E1BLQ5_BOVIN", "mass": { "chemical_mass": 53778.0, "monoisotopic_mass": 53778.0 }, "refseq": { "ac": "NP_001192511", "name": "ribosomal protein S6 kinase beta-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192511" }, "gene_names": [ { "name": "RPS6KB2", "type": "recommended", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "name": "RPS6KB2", "type": "synonym", "evidence": [ { "id": "NP_001192511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192511" } ] } ], "protein_names": [ { "name": "Ribosomal protein S6 kinase beta-2", "type": "recommended", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5/entry#names_and_taxonomy" } ] }, { "name": "70 kDa ribosomal protein S6 kinase 2", "type": "synonym", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5/entry#names_and_taxonomy" } ] }, { "name": "p70 ribosomal S6 kinase beta", "type": "synonym", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5/entry#names_and_taxonomy" } ] }, { "name": "ribosomal protein S6 kinase beta-2", "type": "synonym", "evidence": [ { "id": "NP_001192511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192511" } ] } ], "function": [ { "annotation": "Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7.", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ5", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5#function" }, { "database": "UniProtKB", "id": "ARBA00053693", "url": "https://www.uniprot.org/uniprotkb/ARBA00053693#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLQ5", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RPS6KB2", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5", "locus": { "chromosome": "29", "start_pos": 45327155, "end_pos": 45320942, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009175", "url": "https://www.ensembl.org/id/ENSBTAG00000009175" } ] } } ], "crossref": [ { "id": "E1BLQ5", "url": "https://alphafold.ebi.ac.uk/entry/E1BLQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009175", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009175", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05584", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05584", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506083", "url": "https://www.ncbi.nlm.nih.gov/gene/506083", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:506083", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506083", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LTK5", "url": "https://www.orthodb.org/?gene=A0A3Q1LTK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BLQ5", "url": "https://www.orthodb.org/?gene=E1BLQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192511", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192511", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LTK5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLQ5", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLQ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTESSVNPGPERIGPHCFELLRVLGKGNYGKVFQVRKVQGSNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLSEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLELPPYLTPDARDLVKKFLKRNPNQRIGGGPGDAADVQRHPFFRHVNWDDLLARRVDPPFRPSLQSEEDVSQFDSHFTKQTPVDSPDDTTLSESANQAFLGFTYVAPSVLDSIKEAFSFQPKLRSPRRLNSSPRTPVSPLKFSPFEGFRPSPGPQELVEPPLPPLLPPPPPPPPSSTAPLPIRPPSGTKKSKRGRGRPGR", "length": 485, "header": "tr|E1BLQ5-1|E1BLQ5_BOVIN Isoform 1 of Ribosomal protein S6 kinase beta-2 OS=Bos taurus OX=9913 GN=RPS6KB2 PE=3 SV=3 CANONICAL=E1BLQ5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LTK5-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5/entry#A0A3Q1LTK5-1", "sequence": { "sequence": "MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTESSVNPGPERIGPHCFELLRVLGKGNYGKVFQVRKVQGSNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLSEITLALGHLHSQGIIYRDLKPENIMLSSQGVDPRGRRDPHLLRHHRVHPPFTAENRKKTMDKIIRGKLELPPYLTPDARDLVKKFLKRNPNQRIGGGPGDAADVQRHPFFRHVNWDDLLARRVDPPFRPSLQSEEDVSQFDSHFTKQTPVDSPDDTTLSESANQAFLGFTYVAPSVLDSIKEAFSFQPKLRSPRRLNSSPRTPVSPLKFSPFEGFRPSPGPQELVEPPLPPLLPPPPPPPPSSTAPLPIRPPSGTKKSKRGRGRPGR", "length": 443, "header": "tr|A0A3Q1LTK5-1|E1BLQ5_BOVIN Computationally mapped isoform of Ribosomal protein S6 kinase beta-2 OS=Bos taurus OX=9913 GN=RPS6KB2 PE=3 SV=2 CANONICAL=E1BLQ5-1" }, "locus": { "chromosome": "29", "start_pos": 45326922, "end_pos": 45320995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080866.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080866.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063807.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063807.2" } ] } }, { "isoform_ac": "E1BLQ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5/entry#E1BLQ5-1", "sequence": { "sequence": "MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTESSVNPGPERIGPHCFELLRVLGKGNYGKVFQVRKVQGSNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLSEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLELPPYLTPDARDLVKKFLKRNPNQRIGGGPGDAADVQRHPFFRHVNWDDLLARRVDPPFRPSLQSEEDVSQFDSHFTKQTPVDSPDDTTLSESANQAFLGFTYVAPSVLDSIKEAFSFQPKLRSPRRLNSSPRTPVSPLKFSPFEGFRPSPGPQELVEPPLPPLLPPPPPPPPSSTAPLPIRPPSGTKKSKRGRGRPGR", "length": 485, "header": "tr|E1BLQ5-1|E1BLQ5_BOVIN Isoform 1 of Ribosomal protein S6 kinase beta-2 OS=Bos taurus OX=9913 GN=RPS6KB2 PE=3 SV=3 CANONICAL=E1BLQ5-1" }, "locus": { "chromosome": "29", "start_pos": 45326922, "end_pos": 45320995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012092.7", "url": "https://www.ensembl.org/id/ENSBTAT00000012092.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012092.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012092.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:506083", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506083", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ5", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ5", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ5", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ5", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ5", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "TORC1 signaling", "id": "GO:0038202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038202", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ5", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ], "pmid": "" }, { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ5", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] } ] }, { "uniprot_ac": "A0A3Q1LWT7", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LWT7", "database": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] } ] }, { "uniprot_ac": "A0A3Q1MHL3", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q58D94", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] } ] }, { "uniprot_ac": "Q8MIT6", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = 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"Protein" ] }, { "id": "A0ABI0NJT4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGSLCIKVTDDLVCLVYRTDQAQDVKKIEKFHSQLMRLMVAKESRSVAMETD", "length": 86, "header": "tr|A0ABI0NJT4-1|A0ABI0NJT4_BOVIN Isoform 1 of Signal recognition particle 9 kDa protein OS=Bos taurus OX=9913 GN=SRP9 PE=3 SV=1 CANONICAL=A0ABI0NJT4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T845-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJT4/entry#A0AAA9T845-1", "sequence": { "sequence": "MPQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGSLCIKVTDDLVQWHFKYYKILNLRNVIGNLET", "length": 68, "header": "tr|A0AAA9T845-1|A0ABI0NJT4_BOVIN Computationally mapped isoform of Signal recognition particle 9 kDa protein OS=Bos taurus OX=9913 GN=SRP9 PE=3 SV=1 CANONICAL=A0ABI0NJT4-1" }, "locus": { "chromosome": "16", "start_pos": 28809023, "end_pos": 28800119, "strand": "-", "evidence": [ { "database": "Ensembl 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{ "database": "UniProtKB", "id": "A0ABI0NJT4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJT4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "7S RNA binding", "id": "GO:0008312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008312", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJT4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NJT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJT4" }, { "id": "PF05486", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05486" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRP9", "eco_id": "ECO_0000259", "start_pos": 5, 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As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation. It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. 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"https://www.ebi.ac.uk/interpro/entry/IPR018997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VFFRCPM", "url": "https://omabrowser.org/oma/group/VFFRCPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MES6", "url": "https://www.orthodb.org/?gene=F1MES6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23153:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23153:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NJJ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MES6", "url": "https://www.uniprot.org/uniprotkb/F1MES6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MES6-1", "url": "https://www.uniprot.org/uniprotkb/F1MES6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKFFQEIKADIKFKSAGPGQKLTESVGEKAPKEKPSQPPVRQPRQGPTNEAQMAAAAALARLEQKQPRARGPTSQDSIRNQVRKELRAEAAVSGDPEAPGSNTAPEPKEEGSAHLAVPGVYFTCPLTGAILRKDQRDARIREAILMHFSTDPVAASIMKIHTFNKDRDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKVQNKVFQERIHCLEGTHEFFEAIGFQKVLLPIPDQEGPEEFYVLSEAALAQPQSLEWHKEQLLSAEPVRATLARQRRVFRPSTLASQFDLPADFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREREEQREMRKYTYTLLRVRLPDGCLLQGTFYARERVAALYGFVREALQNDWLPFELLASGGQKLSEDENLAFNECGLVPSALLTFSWDAAVLEDIRAAGTQPDTSILKPELLSAIEKL", "length": 441, "header": "tr|A0ABI0NJJ8-1|A0ABI0NJJ8_BOVIN Isoform 1 of UBX domain-containing protein 6 OS=Bos taurus OX=9913 GN=UBXN6 PE=4 SV=1 CANONICAL=A0ABI0NJJ8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NJJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJJ8/entry#A0ABI0NJJ8-1", "sequence": { "sequence": "MKKFFQEIKADIKFKSAGPGQKLTESVGEKAPKEKPSQPPVRQPRQGPTNEAQMAAAAALARLEQKQPRARGPTSQDSIRNQVRKELRAEAAVSGDPEAPGSNTAPEPKEEGSAHLAVPGVYFTCPLTGAILRKDQRDARIREAILMHFSTDPVAASIMKIHTFNKDRDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKVQNKVFQERIHCLEGTHEFFEAIGFQKVLLPIPDQEGPEEFYVLSEAALAQPQSLEWHKEQLLSAEPVRATLARQRRVFRPSTLASQFDLPADFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREREEQREMRKYTYTLLRVRLPDGCLLQGTFYARERVAALYGFVREALQNDWLPFELLASGGQKLSEDENLAFNECGLVPSALLTFSWDAAVLEDIRAAGTQPDTSILKPELLSAIEKL", "length": 441, "header": "tr|A0ABI0NJJ8-1|A0ABI0NJJ8_BOVIN Isoform 1 of UBX domain-containing protein 6 OS=Bos taurus OX=9913 GN=UBXN6 PE=4 SV=1 CANONICAL=A0ABI0NJJ8-1" }, "locus": { "chromosome": "7", "start_pos": 19674521, "end_pos": 19663055, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148376.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148376.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104649.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104649.1" } ] } }, { "isoform_ac": "F1MES6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJJ8/entry#F1MES6-1", "sequence": { "sequence": "MAAAAALARLEQKQPRARGPTSQDSIRNQVRKELRAEAAVSGDPEAPGSNTAPEPKEEGSAHLAVPGVYFTCPLTGAILRKDQRDARIREAILMHFSTDPVAASIMKIHTFNKDRDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKVQNKVFQERIHCLEGTHEFFEAIGFQKVLLPIPDQEGPEEFYVLSEAALAQPQSLEWHKEQLLSAEPVRATLARQRRVFRPSTLASQFDLPADFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREREEQREMRKYTYTLLRVRLPDGCLLQGTFYARERVAALYGFVREALQNDWLPFELLASGGQKLSEDENLAFNECGLVPSALLTFSWDAAVLEDIRAAGTQPDTSILKPELLSAIEKL", "length": 388, "header": "tr|F1MES6-1|A0ABI0NJJ8_BOVIN Computationally mapped isoform of UBX domain-containing protein 6 OS=Bos taurus OX=9913 GN=UBXN6 PE=4 SV=2 CANONICAL=A0ABI0NJJ8-1" }, "locus": { "chromosome": "7", "start_pos": 19674521, "end_pos": 19666177, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010767.6", "url": "https://www.ensembl.org/id/ENSBTAT00000010767.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010767.4", "url": "https://www.ensembl.org/id/ENSBTAP00000010767.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K012-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "Ubxn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCPPPPPGGCRGPEGEPVVLATASADRKMAPRPRGAARRLSRVPGGTSVAEIFSFRWLAACSSPTRALRPPPRGPRRRAAAMKKFFQEIKADIKFKSAGPGQKLTDSAGEKTSKGKSPQLALRQPRQGPTDEAQMAAAAALARLEQKQPRARGPTSQDSIRNQVRKELQAEATSSNNPGAPGTNSVPETKDEISPHLAVPGVFFICPLTGVTLRRDQRDAHIKQAILSHFSTDPVAASIMKIHTFNRDRDRVKLGVDTIAKYLDNIHLHPEEEKYQKIKLQNKVFQERINCLEGSHEFFEAIGFKKVTLPVPDQEGQEFYVLGEDARAQPQNLERHKQQLLGAEPVRATLDRQLRVFRPSALASHFELPSDFFSLTAEEVKREQRLRTEAVERLSSLRTKAMREKEEQRELRKYTYALLRVRLPDGCLLQGTFYAREKLSVLFQFVREALQNDWLPFELRASGGQKLEENEALALNECGLVPSALLTFSWDASVLEDIRAAGAEPAKSVLRPELLAAIEQLS", "length": 524 }, "evidence": [ { "id": "A0ABI0NJJ8", "url": "https://omabrowser.org/oma/group/A0ABI0NJJ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1AAH8-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "UBXN6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRKFFQEIKADLKFRSAGPGQKLSEPARYGALRRRVPKEKPKAEAAPKPRHGPTDEAQMAAAAALARMELKPKAKPPSSQGAIKNQVRKELMAEAAASVKGVSADQEDPAFSDKETAAEPSVSGVYFICPLTSTVVRKDEKEKHIREAIKSYFSVDPVAASIMEIHTLNKDREKVRVGVETMAKYLDNIYLHPEEEKYQKIKLQNKVFQERINCLEGIHRFFQSVGFETRTLPVPGQDTTEEYYVLKEEMLTKLEDLKDYKEQLLSCEPLRLQLDRQLCVFKPSPEAARFELPNDFYNLTAEEIKREQRLRTEAVEKASMLRTRAMREKEEQREMRKYNYTLLRVRLPDGYLLQGTFYAREPVSVLYNFVREALRDNWLPFELLGPGGLKLTDENLAFNECGLVPSALLTLAWDAAVMSDIEASGQEQPASPLKPELLSHVQTLS", "length": 445 }, "evidence": [ { "id": "A0ABI0NJJ8", "url": "https://omabrowser.org/oma/group/A0ABI0NJJ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HCG0-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "Ubxn6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKKFFQEIKADIKFKSAGPGQKLTDSAGQKTPKEKSPQQALQQPRQGPTDEAQMAAAAALARLEQKQPRARGPTSQDSIRNQVRKELQAEATSSNSPGAPGTNLAPEPKEEISPHLAVPGVYFICPLTGVTLRRDQRDAHIKEAILSHFSTDPVAASIMKIHTFNRDRDRVKLGVDTIAKYLDNIHLHPEEEKYQKIKLQNKVFQERINCLEGTHEFFEAIGFKKMTLPVPDQEGSEEFYVLGEATRAQPQSLEQHKQQLLSAEPVRAMLDRQRRVFRPSALASHFELPADFFSLTAEEVKREQRLRTEAVERLSSLRTKAMREKEEQRELRKYTYALLRVRLPDGCLLQGTFYARERLPVLFQFVREALQNDWLPFELRASGGQRLVEDEALALNECGLVPSALLTFSWDASVLEDMRAAGAEPATCVLRPELLAAIEQLS", "length": 442 }, "evidence": [ { "id": "A0ABI0NJJ8", "url": "https://omabrowser.org/oma/group/A0ABI0NJJ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1LYI0-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "ubxn6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKKFFDDIKKDIKFKSAGPGKKLTDESSSKPQASQASHAASRKAPTAGAQMAGAAALARIEQQHRPKVHTSQDAIRNQVKRELEAEAAAVVASLKNTEIEGSAVPQRDSSSFSVSGVFFTCPLTGKTVTKAERELHIKEAILMRFSEDAIEASIMMIHTFNKDKEKVKAAIDIISKYIENICKNPTEEKYRKIKVGNKVFQEKVSGIEGAREYLQALGFESSTLPIDGEEKTEDFLVLPEQDSDALEQMKIHLERLQKGEAVRAKLDRQLQVFRPSQNATHFELPPDFYNLSAEELKKEQQLKSEMVERNAMLRTKAMREKDEQRERRKYNYALLRVRLPDGNILQGTFLAWERLSALYQFVRDSLENDWQPFELMAPGGQKLKDDEETPINECNLAPAALLTFSWDAAVQADIAAAGGKTAVLLKQALLENIKSLS", "length": 437 }, "evidence": [ { "id": "A0ABI0NJJ8", "url": "https://omabrowser.org/oma/group/A0ABI0NJJ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q99PL6-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "Ubxn6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKFFQEIKADIKFKSAGPGQKLTDSAGEKTTKGKSPQLALRQPRQGPTDEAQMAAAAALARLEQKQPRARGPTSQDSIRNQVRKELQAEATSSNNPGAPGTNSVPEPKEEISPHLAVPGVFFICPLTGVTLRRDQRDAHIKQAILSHFSTDPVAASIMKIHTFNRDRDRVKLGVDTIAKYLDNIHLHPEEEKYQKIKLQNKVFQERINCLEGSHEFFEAIGFKKVTLPVPDQEGQEEFYVLGEDARAQPQNLARHKQQLLDAEPVRATLDRQLRVFRPSALASHFELPSDFFSLTAEEVKREQRLRTEAVERLSSLRTKAMREKEEQRELRKYTYALVRVRLPDGCLLQGTFYAREKLSALFRFVREALQNDWLPFELRASGGQKLEENEALALNECGLVPSALLTFSWDASVLEDIRAAGAEPAKSVLRPELLAAIEQLS", "length": 442 }, "evidence": [ { "id": "A0ABI0NJJ8", "url": "https://omabrowser.org/oma/group/A0ABI0NJJ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZV1-1", "protein_name": "UBX domain-containing protein 6", "gene_name": "UBXN6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKFFQEFKADIKFKSAGPGQKLKESVGEKAHKEKPNQPAPRPPRQGPTNEAQMAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKEAILLHFSTDPVAASIMKIYTFNKDQDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKLQNKVFQERINCLEGTHEFFEAIGFQKVLLPAQDQEDPEEFYVLSETTLAQPQSLERHKEQLLAAEPVRAKLDRQRRVFQPSPLASQFELPGDFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREKEEQRGLRKYNYTLLRVRLPDGCLLQGTFYARERLGAVYGFVREALQSDWLPFELLASGGQKLSEDENLALNECGLVPSALLTFSWDMAVLEDIKAAGAEPDSILKPELLSAIEKLL", "length": 441 }, "evidence": [ { "id": "A0ABI0NJJ8", "url": "https://omabrowser.org/oma/group/A0ABI0NJJ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJJ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJJ8" }, { "id": "PS50033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBX", "eco_id": "ECO_0000259", "start_pos": 332, "end_pos": 408, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 294, "end_pos": 296 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NL85-1", "uniprot_ac": "A0ABI0NL85", "uniprot_id": "A0ABI0NL85_BOVIN", "mass": { "chemical_mass": 69188.0, "monoisotopic_mass": 69188.0 }, "refseq": { "ac": "XP_005204973", "name": "forkhead box protein J3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204973" }, "gene_names": [ { "name": "FOXJ3", "type": "recommended", "evidence": [ { "id": "A0ABI0NL85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ] }, { "name": "FOXJ3", "type": "synonym", "evidence": [ { "id": "XP_005204973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204973" } ] } ], "protein_names": [ { "name": "Forkhead box J3", "type": "synonym", "evidence": [ { "id": "A0ABI0NL85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85/entry#names_and_taxonomy" } ] }, { "name": "forkhead box protein J3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005204973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204973" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FOXJ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85", "locus": { "chromosome": "3", "start_pos": 104003584, "end_pos": 103880787, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015887", "url": "https://www.ensembl.org/id/ENSBTAG00000015887" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015887", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015887", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539458", "url": "https://www.ncbi.nlm.nih.gov/gene/539458", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539458", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539458", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LJR0", "url": "https://www.orthodb.org/?gene=A0A3Q1LJR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BK17", "url": "https://www.orthodb.org/?gene=E1BK17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46078", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46078", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46078:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46078:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005204973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204973", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJR0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNQ3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWK6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWK6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL85-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK17", "url": "https://www.uniprot.org/uniprotkb/E1BK17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK17-1", "url": "https://www.uniprot.org/uniprotkb/E1BK17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDAAQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDALPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVPQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLTNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPSHRPHGLPQHPQRPQHPAPHPQQHNQLQSPHPQHPSPHQHIQHHPNHQHQTHQTLTHQAPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTIAGHHGAMSQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 625, "header": "tr|A0ABI0NL85-1|A0ABI0NL85_BOVIN Isoform 1 of Forkhead box J3 OS=Bos taurus OX=9913 GN=FOXJ3 PE=4 SV=1 CANONICAL=A0ABI0NL85-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJR0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85/entry#A0A3Q1LJR0-1", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDAAQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDALPTRPKKRARSVERVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVPQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLTNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPSHRPHGLPQHPQRPQHPAPHPQQHNQLQSPHPQHPSPHQHIQHHPNHQHQTHQTLTHQAPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTIAGHHGAMSQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 591, "header": "tr|A0A3Q1LJR0-1|A0ABI0NL85_BOVIN Computationally mapped isoform of Forkhead box J3 OS=Bos taurus OX=9913 GN=FOXJ3 PE=4 SV=1 CANONICAL=A0ABI0NL85-1" }, "locus": { "chromosome": "3", "start_pos": 104002580, "end_pos": 103902309, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084389.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084389.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056698.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056698.1" } ] } }, { "isoform_ac": "A0AAA9SNQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85/entry#A0AAA9SNQ3-1", "sequence": { "sequence": "MTSELESSLTSMDWLPQLTMRAAIQKSDAAQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDALPTRPKKRARSVERVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVPQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLTNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPSHRPHGLPQHPQRPQHPAPHPQQHNQLQSPHPQHPSPHQHIQHHPNHQHQTHQTLTHQAPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTIAGHHGAMSQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 576, "header": "tr|A0AAA9SNQ3-1|A0ABI0NL85_BOVIN Computationally mapped isoform of Forkhead box J3 OS=Bos taurus OX=9913 GN=FOXJ3 PE=4 SV=2 CANONICAL=A0ABI0NL85-1" }, "locus": { "chromosome": "3", "start_pos": 104002580, "end_pos": 103927121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124894.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124894.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086987.2", "url": "https://www.ensembl.org/id/ENSBTAP00000086987.2" } ] } }, { "isoform_ac": "A0AAA9TWK6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85/entry#A0AAA9TWK6-1", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDAAQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKGSYWAIDTNPKEDALPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVPQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLTNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPSHRPHGLPQHPQRPQHPAPHPQQHNQLQSPHPQHPSPHQHIQHHPNHQHQTHQTLTHQAPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTIAGHHGAMSQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 600, "header": "tr|A0AAA9TWK6-1|A0ABI0NL85_BOVIN Computationally mapped isoform of Forkhead box J3 OS=Bos taurus OX=9913 GN=FOXJ3 PE=4 SV=1 CANONICAL=A0ABI0NL85-1" }, "locus": { "chromosome": "3", "start_pos": 104002580, "end_pos": 103902309, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132658.2", "url": "https://www.ensembl.org/id/ENSBTAT00000132658.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102725.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102725.1" } ] } }, { "isoform_ac": "A0ABI0NL85-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85/entry#A0ABI0NL85-1", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDAAQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDALPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVPQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLTNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPSHRPHGLPQHPQRPQHPAPHPQQHNQLQSPHPQHPSPHQHIQHHPNHQHQTHQTLTHQAPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTIAGHHGAMSQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 625, "header": "tr|A0ABI0NL85-1|A0ABI0NL85_BOVIN Isoform 1 of Forkhead box J3 OS=Bos taurus OX=9913 GN=FOXJ3 PE=4 SV=1 CANONICAL=A0ABI0NL85-1" }, "locus": { "chromosome": "3", "start_pos": 104002580, "end_pos": 103902309, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154191.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154191.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105736.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105736.1" } ] } }, { "isoform_ac": "E1BK17-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85/entry#E1BK17-1", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDAAQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDALPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKPQNLAGLKEETDGSLTSEVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVPQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLTNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPSHRPHGLPQHPQRPQHPAPHPQQHNQLQSPHPQHPSPHQHIQHHPNHQHQTHQTLTHQAPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTIAGHHGAMSQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 643, "header": "tr|E1BK17-1|A0ABI0NL85_BOVIN Computationally mapped isoform of Forkhead box J3 OS=Bos taurus OX=9913 GN=FOXJ3 PE=4 SV=4 CANONICAL=A0ABI0NL85-1" }, "locus": { "chromosome": "3", "start_pos": 104002580, "end_pos": 103902309, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000060940.5", "url": "https://www.ensembl.org/id/ENSBTAT00000060940.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053827.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053827.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539458", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539458", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL85", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NL85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL85" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 173, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 477, "end_pos": 479 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 63, "end_pos": 65 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMP8-1", "uniprot_ac": "E1BMP8", "uniprot_id": "E1BMP8_BOVIN", "mass": { "chemical_mass": 154245.0, "monoisotopic_mass": 154245.0 }, "refseq": { "ac": "XP_002694612", "name": "protein strawberry notch homolog 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694612" }, "gene_names": [ { "name": "SBNO1", "type": "recommended", "evidence": [ { "id": "E1BMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP8" } ] }, { "name": "SBNO1", "type": "synonym", "evidence": [ { "id": "XP_002694612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694612" } ] } ], "protein_names": [ { "name": "Protein strawberry notch homolog 1", "type": "recommended", "evidence": [ { "id": "E1BMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP8/entry#names_and_taxonomy" } ] }, { "name": "protein strawberry notch homolog 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002694612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694612" } ] } ], "function": [ { "annotation": "Plays a crucial role in the regulation of neural stem cells (NSCs) proliferation. Enhances the phosphorylation of GSK3B through the PI3K-Akt signaling pathway, thereby upregulating the Wnt/beta-catenin signaling pathway and promoting the proliferation of NSCs. Improves ischemic stroke recovery while inhibiting neuroinflammation through small extracellular vesicles (sEVs)-mediated mechanism. Enhances the secretion of sEVs from NSCs, which in turn inhibit both the MAPK and NF-kappaB pathways in microglia. This inhibition suppresses the pro-inflammatory M1 polarization of microglia, promoting a shift towards the M2 anti-inflammatory phenotype, which is beneficial for reducing neuroinflammation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LVJ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVJ6#function" }, { "database": "UniProtKB", "id": "ARBA00057925", "url": "https://www.uniprot.org/uniprotkb/ARBA00057925#function" }, { "database": "UniProtKB", "id": "E1BMP8", "url": "https://www.uniprot.org/uniprotkb/E1BMP8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMP8", "url": "https://www.uniprot.org/uniprotkb/E1BMP8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SBNO1", "url": "https://www.uniprot.org/uniprotkb/E1BMP8", "locus": { "chromosome": "17", "start_pos": 52290590, "end_pos": 52247385, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020505", "url": "https://www.ensembl.org/id/ENSBTAG00000020505" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020505", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020505", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540582", "url": "https://www.ncbi.nlm.nih.gov/gene/540582", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540582", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540582", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KLWMEAR", "url": "https://omabrowser.org/oma/group/KLWMEAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LVJ6", "url": "https://www.orthodb.org/?gene=A0A3Q1LVJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BMP8", "url": "https://www.orthodb.org/?gene=E1BMP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12706:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12706:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13871", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13871", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13872", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13872", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002694612", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694612", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVJ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMP8", "url": "https://www.uniprot.org/uniprotkb/E1BMP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMP8-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDIDGGDAGLATPTPTPPIQQSVPLSALELGLETEAAVPVKQEPETVPTPALLNVRQQPPSTTTFVLNQINQLPTLGSTIVMTKTPPVTTNRQTITLTKFIQTTANTRPSVSAPAVRNAMTSAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGTVKKESSNKEVARIWINDMKMRSFSPTMKVPVVKEEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNSSSPRDSPCKENKTKKRKGEEITREAKKARKIGGLTGSSSDDSGSESDASDNEESDYESSKNMSSGDDDDFNPFRDESSEDDEDDPWLIRKDHKKNKDKKKRKSIDPDSIQSALLASGLGSKRPSFSSTPVISPAPNSAPANSNTNSNSSLITSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLEIYADLKKKYKKVVSDDAVVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLINLLSTSDQSQQLAVQQKQLWQQRHPQSIASLSST", "length": 1393, "header": "tr|E1BMP8-1|E1BMP8_BOVIN Isoform 1 of Protein strawberry notch homolog 1 OS=Bos taurus OX=9913 GN=SBNO1 PE=3 SV=3 CANONICAL=E1BMP8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVJ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP8/entry#A0A3Q1LVJ6-1", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDIDGGDAGLATPTPTPPIQQQQPPSTTTFVLNQINQLPTLGSTIVMTKTPPVTTNRQTITLTKFIQTTANTRPSVSAPAVRNAMTSAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGTVKKESSNKEVARIWINDMKMRSFSPTMKVPVVKEEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNSSSPRDSPCKENKTKKRKGEEITREAKKARKIGGLTGSSSDDSGSESDASDNEESDYESSKNMSSGDDDDFNPFRDESSEDDEDDPWLIRKDHKKNKDKKKRKSIDPDSIQSALLASGLGSKRPSFSSTPVISPAPNSAPANSNTNSNSSLITSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLEIYADLKKKYKKVVSDDAVVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLINLLSTSDQSQQLAVQQKQLWQQRHPQSIASLSST", "length": 1358, "header": "tr|A0A3Q1LVJ6-1|E1BMP8_BOVIN Computationally mapped isoform of Protein strawberry notch homolog 1 OS=Bos taurus OX=9913 GN=SBNO1 PE=3 SV=1 CANONICAL=E1BMP8-1" }, "locus": { "chromosome": "17", "start_pos": 52289586, "end_pos": 52247385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076592.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076592.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059333.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059333.1" } ] } }, { "isoform_ac": "E1BMP8-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP8/entry#E1BMP8-1", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDIDGGDAGLATPTPTPPIQQSVPLSALELGLETEAAVPVKQEPETVPTPALLNVRQQPPSTTTFVLNQINQLPTLGSTIVMTKTPPVTTNRQTITLTKFIQTTANTRPSVSAPAVRNAMTSAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGTVKKESSNKEVARIWINDMKMRSFSPTMKVPVVKEEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNSSSPRDSPCKENKTKKRKGEEITREAKKARKIGGLTGSSSDDSGSESDASDNEESDYESSKNMSSGDDDDFNPFRDESSEDDEDDPWLIRKDHKKNKDKKKRKSIDPDSIQSALLASGLGSKRPSFSSTPVISPAPNSAPANSNTNSNSSLITSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLEIYADLKKKYKKVVSDDAVVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLINLLSTSDQSQQLAVQQKQLWQQRHPQSIASLSST", "length": 1393, "header": "tr|E1BMP8-1|E1BMP8_BOVIN Isoform 1 of Protein strawberry notch homolog 1 OS=Bos taurus OX=9913 GN=SBNO1 PE=3 SV=3 CANONICAL=E1BMP8-1" }, "locus": { "chromosome": "17", "start_pos": 52289586, "end_pos": 52247385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027325.8", "url": "https://www.ensembl.org/id/ENSBTAT00000027325.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027325.6", "url": "https://www.ensembl.org/id/ENSBTAP00000027325.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 72, "start_aa": "Thr", "end_pos": 72, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr72", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540582", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540582", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MLK1-1", "protein_name": "Protein strawberry notch homolog 1", "gene_name": "Sbno1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDVDGGDAGLATPTPPSVQQSMPLSALELGLETEAAVPVKQEPETMSTPALLNVRQQPPSTTTFVLNQINQLPTLGSTIVMTKTPPATTNRQTITLTKFIQTTANTRPSVSAPAVRNAMPPAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGAVKKESSNKEVARIWINDMKMRSFSPTMKVPVVKEEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAVTYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLKDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSPCKENKIKKRKGEEITREAKKARKVGGLTGSSSDDSGSESDVSDNEESDYESSKNMSSGDDDDFNPFRDESSEDNEDDPWLIRKEHKKSKDKKKKKSIDPDSIQSALLASGLGSKRPSFSSAPVISPAPNSAPANSNTNSNNSLITSQDAVERAQQMKKDLLDKLDKLAEDLPPNTLDELIDDLGGPENVAEMTGRKGRVVSNDDGSISYESRTEIDVPVEILNITEKQRFMDGKKNIAIISEAASSGISLQADRRAQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLIYRPNTGKQLKLEIYADLKKKYKKVVSDDALVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQKQLWQQHHPQSITNLSNS", "length": 1392 }, "evidence": [ { "id": "E1BMP8", "url": "https://omabrowser.org/oma/group/E1BMP8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V1A4E3-1", "protein_name": "Protein strawberry notch homolog 1", "gene_name": "SBNO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDIDSPDVVLATPTPAVQQSVPLSALDLGLETEAPAAVKQEPETVSTPALLNVRQPPSTTTFVLNQINQLPTLGTTIVMTKTTPVTTTRQTITVAKIIQTSTTTRPSVAAPAVRNALTTAPSKDQIQLKDLLKNNSLNELMKLKPPPNIAQPVATAATDLSNGAVKKEASTKEVARIWINDVKMRSFSPTMKVPAVKEEEEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDPVVETSSLSSVTPPDVWYQTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLGRKRAVWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGEDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFSGVTFKIDEVLLSQEYVKMYNKSVKLWVSARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVFQSLIEKHFPAPDRKKLFSLLGIDLTAQSNNNSPRDSPCKENKIKKRKGEEVSREAKKARKTGGLAGSSSDESESESDASDNEESDNESSRFLSSGDDDDFNPFRDESSEDDEDDPWLIRKEHKKVKEKKKKKSIDPDSIQSALLASGLGSKRPSCFTSTVGTTTSSTNASANSNTNSSFVTSQDAVERAQQMKKELLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATETRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDFPGDFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFSDTLNAVIQNAKKNGRYDMGILDLGSGDEKVRKADVKKFLTPGYSTSGHVELYTISVERGMSWDEATKIWAEQTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLETCADLKKKYKKVPSEDALPHWLEQYNSSADTCTHAYWRGNCKKAGLGLVCEVGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQQQIWQQHHPQSITNFNNA", "length": 1389 }, "evidence": [ { "id": "E1BMP8", "url": "https://omabrowser.org/oma/group/E1BMP8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A3KN83-1", "protein_name": "Protein strawberry notch homolog 1", "gene_name": "SBNO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDIDGGDAGLATPMPTPSVQQSVPLSALELGLETEAAVPVKQEPETVPTPALLNVRQQPPSTTTFVLNQINHLPPLGSTIVMTKTPPVTTNRQTITLTKFIQTTASTRPSVSAPTVRNAMTSAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGTVKKESSNKEGARMWINDMKMRSFSPTMKVPVVKEDDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSPCKENKIKKRKGEEITREAKKARKVGGLTGSSSDDSGSESDASDNEESDYESSKNMSSGDDDDFNPFLDESNEDDENDPWLIRKDHKKNKEKKKKKSIDPDSIQSALLASGLGSKRPSFSSTPVISPAPNSTPANSNTNSNSSLITSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLEIYADLKKKYKKVVSDDALMHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQKQLWQQHHPQSITNLSNA", "length": 1393 }, "evidence": [ { "id": "E1BMP8", "url": "https://omabrowser.org/oma/group/E1BMP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BJL5-1", "protein_name": "Protein strawberry notch homolog 1", "gene_name": "Sbno1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDVDGGDAGLATPTPPSVQQQQPPSTTTFVLNQINQLPTLGSTIVMTKTPPATTNRQTITLTKFIQTTANTRPSVSAPAVRNAIPPAPAKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAAADVSNGAVKKESSNKEVARVWINDMKMRSFSPTMKVPVVREEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAVTYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSAKKARKIGGLTGSSSDDSGSESDVSDNEESDYESSKNMSSGDDDDFNPFRDDNSSLITSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWDEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLIYRPNTGKQLKLEIYADLKKKYKKVVSDDALVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQKQLWQQHHPQSITNLSNV", "length": 1269 }, "evidence": [ { "id": "E1BMP8", "url": "https://omabrowser.org/oma/group/E1BMP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q689Z5-1", "protein_name": "Protein strawberry notch homolog 1", "gene_name": "Sbno1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVEPGQDLLLAALSESGISPNDLFDVDGGDAGLATPTPPSVQQSVPLSALELGLETEAAVPVKQEPEPMSTPALLNVRQPPSTTTFVLNQINQLPTLGSTIVMTKTPPATTNRQTITLTKFIQTTANTRPSVSAPAVRNAMPAAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGAVKKESSNKEVARIWINDMKMRSFSPTMKVPVVKEEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAVTYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSPCKENKIKKRKGEEITREAKKARKVGGLTGSSSDDSGSESVSDNDESDYESSKNMSSGDDDDFNPFRDESSEDNEDDPWLIRKDHKKSKDKKKKKSIDPDSIQSALLASGLGSKRPSFSSAPVISPASNSAPANSNSNSNSSLVTSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLEGLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKSGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLIYRPNTGKQLKLEIYADLKKKYKKVVSDDALVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQKQLWQQHHPQSITNLSNL", "length": 1390 }, "evidence": [ { "id": "E1BMP8", "url": "https://omabrowser.org/oma/group/E1BMP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BMP8", "url": "https://www.uniprot.org/uniprotkb/E1BMP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BMP8", "url": "https://www.uniprot.org/uniprotkb/E1BMP8" } ], "pmid": "" }, { "name": "positive regulation of signal transduction", "id": "GO:0009967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009967", "evidence": [ { "database": "UniProtKB", "id": "E1BMP8", "url": "https://www.uniprot.org/uniprotkb/E1BMP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "E1BMP8", "url": "https://www.uniprot.org/uniprotkb/E1BMP8" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "E1BMP8", "url": "https://www.uniprot.org/uniprotkb/E1BMP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1271, "end_pos": 1273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" }, { "start_pos": 921, "end_pos": 923, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP8" }, { "id": "PF25373", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25373" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SBNO alpha/beta", "eco_id": "ECO_0000259", "start_pos": 1186, "end_pos": 1300, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP8" }, { "id": "PF13872", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13872" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Strawberry notch AAA", "eco_id": "ECO_0000259", "start_pos": 255, "end_pos": 560, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP8" }, { "id": "PF13871", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13871" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Strawberry notch helicase C", "eco_id": "ECO_0000259", "start_pos": 872, "end_pos": 1148, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 39, 72 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1271, "end_pos": 1273 }, { "start_pos": 160, "end_pos": 162 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 690, "end_pos": 692 }, { "start_pos": 702, "end_pos": 704 }, { "start_pos": 752, "end_pos": 754 }, { "start_pos": 838, "end_pos": 840 }, { "start_pos": 921, "end_pos": 923 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM32-1", "uniprot_ac": "E1BM32", "uniprot_id": "E1BM32_BOVIN", "mass": { "chemical_mass": 103110.0, "monoisotopic_mass": 103110.0 }, "refseq": { "ac": "NP_001178128", "name": "sodium/calcium exchanger 3 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178128" }, "gene_names": [ { "name": "SLC8A3", "type": "recommended", "evidence": [ { "id": "E1BM32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ] }, { "name": "SLC8A3", "type": "synonym", "evidence": [ { "id": "NP_001178128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178128" } ] } ], "protein_names": [ { "name": "Sodium/calcium exchanger 1", "type": "recommended", "evidence": [ { "id": "E1BM32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM32/entry#names_and_taxonomy" } ] }, { "name": "Na(+)/Ca(2+)-exchange protein 1", "type": "synonym", "evidence": [ { "id": "E1BM32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM32/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 8 member 1", "type": "synonym", "evidence": [ { "id": "E1BM32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM32/entry#names_and_taxonomy" } ] }, { "name": "sodium/calcium exchanger 3 precursor", "type": "synonym", "evidence": [ { "id": "NP_001178128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178128" } ] }, { "name": "solute carrier family 8 (sodium-calcium exchanger), member 3", "type": "synonym", "evidence": [ { "id": "NP_001178128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178128" } ] } ], "function": [ { "annotation": "Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline. Required for normal embryonic heart development and the onset of heart contractions.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW31#function" }, { "database": "UniProtKB", "id": "ARBA00045279", "url": "https://www.uniprot.org/uniprotkb/ARBA00045279#function" }, { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC8A3", "url": "https://www.uniprot.org/uniprotkb/E1BM32", "locus": { "chromosome": "10", "start_pos": 81763024, "end_pos": 81907325, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000027080", "url": "https://www.ensembl.org/id/ENSBTAG00000027080" } ] } } ], "crossref": [ { "id": "E1BM32", "url": "https://alphafold.ebi.ac.uk/entry/E1BM32", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000027080", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000027080", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540307", "url": "https://www.ncbi.nlm.nih.gov/gene/540307", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540307", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540307", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VEMANYH", "url": "https://omabrowser.org/oma/group/VEMANYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM32", "url": "https://www.orthodb.org/?gene=E1BM32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11878", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11878", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11878:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11878:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16494", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178128", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178128", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "69955", "url": "https://www.rhea-db.org/rhea/69955", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LW31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LW31-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM32-1", "url": "https://www.uniprot.org/uniprotkb/E1BM32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWLRLQPLTSAFLHFGLITFVLFLNGLRAEAGGSGDVPSTGQNNESCTGSSDCKEGVILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGHLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKTSSMSEVHADEPEDFVSKVFFDPCSYQCLENCGAVLLTVVRKGGDTSKTLYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRMEEEQPEEGMSPRALNSPPLPRAVLVSPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDIYGELEFKNDETVKTVRVKIVDEEEYERQENFFIVLGEPKWMERGISALLLSTEVTDRKLTVEEEEAKRIAEMGKPILGEHPKLEVIIEESYEFKTTVDKLIRKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVIFVAFGTSVPDTFASKAAAIQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF", "length": 927, "header": "tr|E1BM32-1|E1BM32_BOVIN Isoform 1 of Sodium/calcium exchanger 1 OS=Bos taurus OX=9913 GN=SLC8A3 PE=3 SV=3 CANONICAL=E1BM32-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LW31-1", "url": "https://www.uniprot.org/uniprotkb/E1BM32/entry#A0A3Q1LW31-1", "sequence": { "sequence": "MAWLRLQPLTSAFLHFGLITFVLFLNGLRAEAGGSGDVPSTGQNNESCTGSSDCKEGVILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGHLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKTSSMSEVHADEPEDFVSKVFFDPCSYQCLENCGAVLLTVVRKGGDTSKTLYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRMEEEQPEEGMSPRALNSPPLPRAVLVSPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDIYGELEFKNDETVKTVHIKVIDGEAYEKNKNYFIEMMGPRMVDMSFQKALLLSTDRKLTVEEEEAKRIAEMGKPILGEHPKLEVIIEESYEFKTTVDKLIRKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVIFVAFGTSVPDTFASKAAAIQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF", "length": 925, "header": "tr|A0A3Q1LW31-1|E1BM32_BOVIN Computationally mapped isoform of Sodium/calcium exchanger 1 OS=Bos taurus OX=9913 GN=SLC8A3 PE=3 SV=1 CANONICAL=E1BM32-1" }, "locus": { "chromosome": "10", "start_pos": 81907325, "end_pos": 81764028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077819.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077819.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059584.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059584.2" } ] } }, { "isoform_ac": "A0A3Q1LZN2-1", "url": "https://www.uniprot.org/uniprotkb/E1BM32/entry#A0A3Q1LZN2-1", "sequence": { "sequence": "MAWLRLQPLTSAFLHFGLITFVLFLNGLRAEAGGSGDVPSTGQNNESCTGSSDCKEGVILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGHLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKTSSMSEVHADEPEDFVSKVFFDPCSYQCLENCGAVLLTVVRKGGDTSKTLYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRMEEEQPEEGMSPRALNSPPLPRAVLVSPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDIYGELEFKNDETVKTVRVKIVDEEEYERQENFFIVLGEPKWMERGISALLLSTEVTDRKLTVEEEEAKRIAEMGKPILGEHPKLEVIIEESYEFKTTVDKLIRKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVIFVAFGTSVPGESEGVFDQRECYLDQMSPPICLIIFPTISDLSLTEPLPLRCMKVNPRDPC", "length": 853, "header": "tr|A0A3Q1LZN2-1|E1BM32_BOVIN Computationally mapped isoform of Sodium/calcium exchanger 1 OS=Bos taurus OX=9913 GN=SLC8A3 PE=3 SV=1 CANONICAL=E1BM32-1" }, "locus": { "chromosome": "10", "start_pos": 81907325, "end_pos": 81766542, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079972.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079972.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063109.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063109.2" } ] } }, { "isoform_ac": "E1BM32-1", "url": "https://www.uniprot.org/uniprotkb/E1BM32/entry#E1BM32-1", "sequence": { "sequence": "MAWLRLQPLTSAFLHFGLITFVLFLNGLRAEAGGSGDVPSTGQNNESCTGSSDCKEGVILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGHLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKTSSMSEVHADEPEDFVSKVFFDPCSYQCLENCGAVLLTVVRKGGDTSKTLYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRMEEEQPEEGMSPRALNSPPLPRAVLVSPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDIYGELEFKNDETVKTVRVKIVDEEEYERQENFFIVLGEPKWMERGISALLLSTEVTDRKLTVEEEEAKRIAEMGKPILGEHPKLEVIIEESYEFKTTVDKLIRKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVIFVAFGTSVPDTFASKAAAIQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF", "length": 927, "header": "tr|E1BM32-1|E1BM32_BOVIN Isoform 1 of Sodium/calcium exchanger 1 OS=Bos taurus OX=9913 GN=SLC8A3 PE=3 SV=3 CANONICAL=E1BM32-1" }, "locus": { "chromosome": "10", "start_pos": 81907325, "end_pos": 81764028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022798.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022798.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040809.4", "url": "https://www.ensembl.org/id/ENSBTAP00000040809.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540307", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540307", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B340-1", "protein_name": "Sodium/calcium exchanger 3 isoform X1", "gene_name": "slc8a3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDRSRTKTSAYLWLGVVSVATAFLCAEARVTPSPPLTNNTTCVGETDRCKPGIILPIWYPEDPSMGDKIARVIVYFVAMIYMFLGVSIIADRFMAAIEVITSQEKEIIIKRPNGETTTTTIRVWNETVSNLTLMALGSSAPEILLSLIEICGHEFHAGELGPSTIVGSAAFNMFVIIGLCVSVIPEGEVRKVKHLRVFFVTAAWSVFAYIWLYMILAVFSPNVVQVWEGLLTLAFFPICVILAWVADRRLLFYKFMHKKYRTDKHRGVIIETEGDRTKGIEMDGKMMNSHFIDGGAASNLMGLIEGKEVDESRRDMIRILKDLKQKHPEKELDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHVAEQAKRSASVQEVHVEEPEEFVSRIMFEPAIYQCLENCGAVLLTAVRKGGDITKTIYVDYKTEDGSANAGADYEFTEGTVVFKPGEVIKEITVGIIDDDIFEEDEHFFVRLSNVRVLETEDEVLSPSSLPYPKALIGFPAVATVTILDDDHAGIFTFESDSMHVSESVGIMEVKVLRTSGARGTVIIPFRTMEGLAKGGGEDFEDAYGELEFKNDETCKTIQVKIIDDEEYEKNKNFYLELAEPRMVDMSLQKALLLADDIQDRKLSSEEEEARRIAEMGKPILGEHSKIEIIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFMEAITVSAGDEDEDEGAEERLPSCFDYVMHFLTVFWKVLFACVPPTEYWNGWACFIVSIIIIGLLTAVIGDLASHFGCTIGLKDSVTAVVFVALGTSIPDTFASKVAAVQDSYADASIGNVTGSNAVNVFLGIGVAWSVAAIYWHMQGRAFEVPAGSLAFSVTLFTIFAFLAVGVLLYRRRPHIGGELGGPRGHRILTTLFFFSLWFLYILFSSLEAYCHIQGF", "length": 923 }, "evidence": [ { "id": "E1BM32", "url": "https://omabrowser.org/oma/group/E1BM32/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A9J7GZ86-1", "protein_name": "Sodium/calcium exchanger 3 isoform X1", "gene_name": "Slc8a3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAWLRLQPLTSAFLHFGLVTFVLFLNGLRAEAGDLGDVPSAGQNNESCSGSSDCKEGVILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFVAGDLGPSTIVGSAAFNMFVIIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGNLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKTSSMSEVHTDEPEDFASKVFFDPCSYQCLENCGAVLLTVVRKGGDVSKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRVEEEQLEEGMPPAMLGSFPLPRAVLASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGELEFKNDETVKTIHIKVIDDEAYEKNKNYFIEMLGPRMVDISVQKALLLSPEVTDRKLTVEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAMQGQEFHVSAGTLAFSVTLFTIFAFVCLSVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF", "length": 928 }, "evidence": [ { "id": "E1BM32", "url": "https://omabrowser.org/oma/group/E1BM32/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1P023-1", "protein_name": "Solute carrier family 8 member A3", "gene_name": "COX16", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAWLSLQPLTSAFLHFGLVTFVLFLHGLQVDAGLTGDSTSSVQNSSCSGSFDCKEGVILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEKEITIKKPNGETTTTTIRIWNETVSNLTLMALGSSAPEILLSLIEVCGHGFVAGDLGPSTIVGSAAFNMFIIIAICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPLCVLLAWIADRRLLFYKYMHKKYRTDKHRGIIIESEGDHPKGIEMDGKMMNSHFLDGNLVTVEGKEVDESRKEMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKSTSLHEVRPDEPEEFISKIYFDPCSYQCLENCGAVLLTVVRKGGDVSKTIYVDYKTEDGSANAGADYEFTEGTVVLKSGETQKDFAVGIIDDDIFEEDEHFFVRLSNLRVVDNEEPPELGNSPYPKAILASPCVATVTILDDDHAGIFTFECDVIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDAYGELEFKNDETVKTIHIKVIDDEEYEKNKSFFIELMSPRMVDMSLQKALLLTQEVAERKLTVEEEEAKRIAEMGKPILGEHPKLEVIIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFLEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCNGWACFVVSILIIGMLTAVIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAAIQDVYADASITNVTGSNAVNVFLGIGLAWSVAAIYWASQGQEFQVSAGTLAFSVTLFTIFAFICISVLLYRRRPHLGGELGGPRGCKLATTLLFVSLWLLYILFATLEAYCYIKGF", "length": 922 }, "evidence": [ { "id": "E1BM32", "url": "https://omabrowser.org/oma/group/E1BM32/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S4A9-1", "protein_name": "Sodium/calcium exchanger 1", "gene_name": "SLC8A3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAWLRLQPLTSAFLHFGLITFVLFLNGLRAEAGGSGDVPSPGQNNESCSGSSDCKEGVILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADRRLLFYKYMHKKYRADKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGHLVPVEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPEDFVSKVFFDPCSYQCLENCGAVLLTVVRKGGDTSKTVYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRIEEEPPEEGTSPMVPNSLPFPRAVLASPCVATVTILDDDHAGIFTFECDTVHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTFGELEFKNDETVKTIRVKIVDEEEYERQENFFIVLGEPKWMERGISVLLLSPEVTDRKLTVEEEEAKRIAEMGKPILGEHPKLEVIIEESYEFKSTVDKLIRKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAAIQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFGSLWLLYILFATLEAYCYIKGF", "length": 927 }, "evidence": [ { "id": "E1BM32", "url": "https://omabrowser.org/oma/group/E1BM32/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P57103-1", "protein_name": "Sodium/calcium exchanger 3", "gene_name": "SLC8A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAWLRLQPLTSAFLHFGLVTFVLFLNGLRAEAGGSGDVPSTGQNNESCSGSSDCKEGVILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGNLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPEDFISKVFFDPCSYQCLENCGAVLLTVVRKGGDMSKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAVLASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGELEFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMERGISALLLSPDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF", "length": 927 }, "evidence": [ { "id": "E1BM32", "url": "https://omabrowser.org/oma/group/E1BM32/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "S4R2P9-1", "protein_name": "Sodium/calcium exchanger 3", "gene_name": "Slc8a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWLRLQPLTSAFLHFGLVTFVLFLNCLRAEAGDSGDVPSAGQNNESCSGSSDCKEGVILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGNFTPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKTSSMSEVHTDEPEDFASKVFFDPCSYQCLENCGAVLLTVVRKGGDISKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRVEEEQLAEGMLPAILNSLPLPRAVLASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDAYGELEFKNDETVKTIHIKVIDDKAYEKNKNYVIEMMGPRMVDMSVQKALLLSPEVTDRKLTVEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAGGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAMQGQEFHVSAGTLAFSVTLFTIFAFVCLSVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF", "length": 928 }, "evidence": [ { "id": "E1BM32", "url": "https://omabrowser.org/oma/group/E1BM32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "calcium:sodium antiporter activity", "id": "GO:0005432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005432", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "cell communication", "id": "GO:0007154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007154", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "learning", "id": "GO:0007612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007612", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "myelination", "id": "GO:0042552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042552", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "mitochondrial calcium ion transmembrane transport", "id": "GO:0006851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006851", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "mitochondrial calcium ion homeostasis", "id": "GO:0051560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051560", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "long-term synaptic potentiation", "id": "GO:0060291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060291", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "oligodendrocyte differentiation", "id": "GO:0048709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048709", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" }, { "name": "regulation of skeletal muscle contraction", "id": "GO:0014819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014819", "evidence": [ { "database": "UniProtKB", "id": "E1BM32", "url": "https://www.uniprot.org/uniprotkb/E1BM32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 823, "end_pos": 825, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "69955", "name": "", "equation": "Ca(2+)(in) + 3 Na(+)(out) = Ca(2+)(out) + 3 Na(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "69955", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69955" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM32-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 927, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM32-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM32" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM32" }, { "id": "SM00237", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00237" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calx-beta", "eco_id": "ECO_0000259", "start_pos": 385, "end_pos": 485, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 135, "end_pos": 137 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 823, "end_pos": 825 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMD4-1", "uniprot_ac": "E1BMD4", "uniprot_id": "E1BMD4_BOVIN", "mass": { "chemical_mass": 150134.0, "monoisotopic_mass": 150134.0 }, "refseq": {}, "gene_names": [ { "name": "PHLPP2", "type": "recommended", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] } ], "protein_names": [ { "name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "type": "recommended", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4/entry#names_and_taxonomy" } ] }, { "name": "PH domain leucine-rich repeat-containing protein phosphatase-like", "type": "synonym", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Protein phosphatase involved in regulation of Akt and PKC signaling. Mediates dephosphorylation in the C-terminal domain hydrophobic motif of members of the AGC Ser/Thr protein kinase family; specifically acts on 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser-657' of PRKCA. Akt regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of Akt triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylates STK4 on 'Thr-387' leading to STK4 activation and apoptosis. Dephosphorylates RPS6KB1 and is involved in regulation of cap-dependent translation. Inhibits cancer cell proliferation and may act as a tumor suppressor. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Dephosphorylates RAF1 inhibiting its kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "E1BMD4", "url": "https://www.uniprot.org/uniprotkb/E1BMD4#function" }, { "database": "UniProtKB", "id": "ARBA00058248", "url": "https://www.uniprot.org/uniprotkb/ARBA00058248#function" }, { "database": "UniProtKB", "id": "A0A3Q1LZ23", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZ23#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMD4", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PHLPP2", "url": "https://www.uniprot.org/uniprotkb/E1BMD4", "locus": { "chromosome": "18", "start_pos": 39416025, "end_pos": 39353960, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007545", "url": "https://www.ensembl.org/id/ENSBTAG00000007545" } ] } } ], "crossref": [ { "id": "ENSBTAG00000007545", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007545", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13322", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13322", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17241", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17241", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "533130", "url": "https://www.ncbi.nlm.nih.gov/gene/533130", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WERNMWF", "url": "https://omabrowser.org/oma/group/WERNMWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LZ23", "url": "https://www.orthodb.org/?gene=A0A3Q1LZ23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M5I8", "url": "https://www.orthodb.org/?gene=A0A3Q1M5I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BMD4", "url": "https://www.orthodb.org/?gene=E1BMD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LZ23", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZ23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZ23-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZ23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5I8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMD4", "url": "https://www.uniprot.org/uniprotkb/E1BMD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMD4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEVEPGPAGPLEPPEPPEAPASRRPGGIRVLKRNMKRNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTTSSASSSSSDLHLVLCTVETPASEICAGEGRESLYLQLHGDLVSRRLEPTERPLQIVYDYLSRLGFDDPARIQEEAANPDLGCMLRFYGEKPCQMDHLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILPLVGGKVEEVKRRQYSLAFSSAGAQAQTYLVSFETLAEYQRWQRQASKVVSQRISTVDLSCHSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTFYKFSQLKGLNLSHNKLGSFPVLLCEIPTLTELNLSCNGFHDLPSQIGSLLNLQTLCLDGNFLTALPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDKVFMAGNRVEVLNLGVLKRMSHVKHVDLRMNHLKTMIIENLEGNKYITHMDLRDNRLTDLDLSSLCNLEQLHCERNQLRELTLSGFSLRTLYANSNRLTTVNVYPVPSLLTSLELSRNLLECVPDWACEAKKIEILDVSYNLLTEVPMRILSSLSLRKLMVGHNHVQSLPTLVEHIPLEVLDVQHNLLTRLPDTLFSKALNLRYLNASANSLESLPSACAGEESLSALQLLYLTNNLLTDQCVPVLVGHPHLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNHISIFPEILQLPQIQFVDLSCNDLTEILIPEALPATLQDLDLTGNTNLVLEHKTLDTFSHITTLKIDQKPLPTTDSTVTSTFWSHGLAEMAGQRNKLCVSALAVDNFAEGVGAVYGMFDGDRNEELPRLLQCTMADVLLEEVQQSTNDTVFMANTFLVSHRKLGMAGQKLGCSALLCYIRPDTADPMNSFSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDPEEAQRVKDQKAIITEDNKVNGVTCCTRLLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQDPLAAAKKLCTLSQSYGCQDNVGAMVVYLNIGEEGCTCEMNGLTLPGPMGFASTTIIKDPPKPTTPSSSSGIASEFSSEMSTSEVSSEVGSTASDEHNTVGLDAGLLPRPERRCSLHPAPTSGVFQRQPSCATFSSNQSDNGLDSDDDQPVEGVITNGSKVEVEVDIHCCRGRDLENSPTLPENSPAPCPEDRSRGSLFGIRRQNSVNSGILLPVSKDRTELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEAPKKKTGYFAAPTQLEPEDQFVIPRDLEEEVKEQMKHHQESRHEPEPSEEDRTELPEEFDTAL", "length": 1355, "header": "tr|E1BMD4-1|E1BMD4_BOVIN Isoform 1 of PH domain leucine-rich repeat-containing protein phosphatase 2 OS=Bos taurus OX=9913 GN=PHLPP2 PE=4 SV=4 CANONICAL=E1BMD4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LZ23-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD4/entry#A0A3Q1LZ23-1", "sequence": { "sequence": "MGEVEPGPAGPLEPPEPPEAPASRRPGGIRVLKRNMKRNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTTSSASSSSSDLHLVLCTVETPASEICAGEGRESLYLQLHGDLVRRLEPTERPLQIVYDYLSRLGFDDPARIQEEAANPDLGCMLRFYGEKPCQMDHLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILPLVGGKVEEVKRRQYSLAFSSAGAQAQTYLVSFETLAEYQRWQRQASKVVSQRISTVDLSCHSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTFYKFSQLKGLNLSHNKLGSFPVLLCEIPTLTELNLSCNGFHDLPSQIGSLLNLQTLCLDGNFLTALPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDKVFMAGNRVEVLNLGVLKRMSHVKHVDLRMNHLKTMIIENLEGNKYITHMDLRDNRLTDLDLSSLCNLEQLHCERNQLRELTLSGFSLRTLYANSNRLTTVNVYPVPSLLTSLELSRNLLECVPDWACEAKKIEILDVSYNLLTEVPMRILSSLSLRKLMVGHNHVQSLPTLVEHIPLEVLDVQHNLLTRLPDTLFSKALNKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNHISIFPEILQLPQIQFVDLSCNDLTEILIPEALPATLQDLDLTGNTNLVLEHKTLDTFSHITTLKIDQKPLPTTDSTVTSTFWSHGLAEMAGQRNKLCVSALAVDNFAEGVGAVYGMFDGDRNEELPRLLQCTMADVLLEEVQQSTNDTVFMANTFLVSHRKLGMAGQKLGCSALLCYIRPDTADPMNSFSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDPEEAQRVKDQKAIITEDNKVNGVTCCTRLLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQDPLAAAKKLCTLSQSYGCQDNVGAMVVYLNIGEEGCTCEMNGLTLPGPMGFASTTIIKDPPKPTTPSSSSGIASEFSSEMSTSEVSSEVGSTASDEHNTVGLDAGLLPRPERRCSLHPAPTSGVFQRQPSCATFSSNQSDNGLDSDDDQPVEGVITNGSKVEVEVDIHCCRGRDLENSPTLPENSPAPCPEDRSRGSLFGIRRQNSVNSGILLPVSKDRTELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEAPKKKTGYFAAPTQLEPEDQFVIPRDLEEEVKEQMKHHQESRHEPEPSEEDRTELPEEFDTAL", "length": 1287, "header": "tr|A0A3Q1LZ23-1|E1BMD4_BOVIN Computationally mapped isoform of PH domain leucine-rich repeat-containing protein phosphatase 2 OS=Bos taurus OX=9913 GN=PHLPP2 PE=4 SV=1 CANONICAL=E1BMD4-1" }, "locus": { "chromosome": "18", "start_pos": 39415482, "end_pos": 39354236, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084605.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084605.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066059.1", "url": "https://www.ensembl.org/id/ENSBTAP00000066059.1" } ] } }, { "isoform_ac": "A0A3Q1M5I8-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD4/entry#A0A3Q1M5I8-1", "sequence": { "sequence": "MGEVEPGPAGPLEPPEPPEAPASRRPGGIRVLKRNMKRNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTTSSASSSSSDLHLVLCTVETPASEICAGEGRESLYLQLHGDLVRRLEPTERPLQIVYDYLSRLGFDDPARIQEEAANPDLGCMLRFYGEKPCQMDHLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILPLVGGKVEEVKRRQYSLAFSSAGAQAQTYLVSFETLAEYQRWQRQASKVVSQRISTVDLSCHSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTFYKFSQLKGLNLSHNKLGSFPVLLCEIPTLTELNLSCNGFHDLPSQIGSLLNLQTLCLDGNFLTALPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDKVFMAGNRVEVLNLGVLKRMSHVKHVDLRMNHLKTMIIENLEGNKYITHMDLRDNRLTDLDLSSLCNLEQLHCERNQLRELTLSGFSLRTLYANSNRLTTVNVYPVPSLLTSLELSRNLLECVPDWACEAKKIEILDVSYNLLTEVPMSLRYLNASANSLESLPSACAGEESLSALQLLYLTNNLLTDQCVPVLVGHPHLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNHISIFPEILQLPQIQFVDLSCNDLTEILIPEALPATLQDLDLTGNTNLVLEHKTLDTFSHITTLKIDQKPLPTTDSTVTSTFWSHGLAEMAGQRNKLCVSALAVDNFAEGVGAVYGMFDGDRNEELPRLLQCTMADVLLEEVQQSTNDTVFMANTFLVSHRKLGMAGQKLGCSALLCYIRPDTADPMNSFSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDPEEAQRVKDQKAIITEDNKVNGVTCCTRLLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQDPLAAAKKLCTLSQSYGCQDNVGAMVVYLNIGEEGCTCEMNGLTLPGPMGFASTTIIKDPPKPTTPSSSSGIASEFSSEMSTSEVSSEVGSTASDEHNTVGLDAGLLPRPERRCSLHPAPTSGVFQRQPSCATFSSNQSDNGLDSDDDQPVEGVITNGSKVEVEVDIHCCRGRDLENSPTLPENSPAPCPEDRSRGSLFGIRRQNSVNSGILLPVSKDRTELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEAPKKKTGYFAAPTQLEPEDQFVIPRDLEEEVKEQMKHHQESRHEPEPSEEDRTELPEEFDTAL", "length": 1302, "header": "tr|A0A3Q1M5I8-1|E1BMD4_BOVIN Computationally mapped isoform of PH domain leucine-rich repeat-containing protein phosphatase 2 OS=Bos taurus OX=9913 GN=PHLPP2 PE=4 SV=2 CANONICAL=E1BMD4-1" }, "locus": { "chromosome": "18", "start_pos": 39415482, "end_pos": 39354236, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084668.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084668.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065178.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065178.2" } ] } }, { "isoform_ac": "E1BMD4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD4/entry#E1BMD4-1", "sequence": { "sequence": "MGEVEPGPAGPLEPPEPPEAPASRRPGGIRVLKRNMKRNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTTSSASSSSSDLHLVLCTVETPASEICAGEGRESLYLQLHGDLVSRRLEPTERPLQIVYDYLSRLGFDDPARIQEEAANPDLGCMLRFYGEKPCQMDHLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILPLVGGKVEEVKRRQYSLAFSSAGAQAQTYLVSFETLAEYQRWQRQASKVVSQRISTVDLSCHSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTFYKFSQLKGLNLSHNKLGSFPVLLCEIPTLTELNLSCNGFHDLPSQIGSLLNLQTLCLDGNFLTALPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDKVFMAGNRVEVLNLGVLKRMSHVKHVDLRMNHLKTMIIENLEGNKYITHMDLRDNRLTDLDLSSLCNLEQLHCERNQLRELTLSGFSLRTLYANSNRLTTVNVYPVPSLLTSLELSRNLLECVPDWACEAKKIEILDVSYNLLTEVPMRILSSLSLRKLMVGHNHVQSLPTLVEHIPLEVLDVQHNLLTRLPDTLFSKALNLRYLNASANSLESLPSACAGEESLSALQLLYLTNNLLTDQCVPVLVGHPHLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNHISIFPEILQLPQIQFVDLSCNDLTEILIPEALPATLQDLDLTGNTNLVLEHKTLDTFSHITTLKIDQKPLPTTDSTVTSTFWSHGLAEMAGQRNKLCVSALAVDNFAEGVGAVYGMFDGDRNEELPRLLQCTMADVLLEEVQQSTNDTVFMANTFLVSHRKLGMAGQKLGCSALLCYIRPDTADPMNSFSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDPEEAQRVKDQKAIITEDNKVNGVTCCTRLLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQDPLAAAKKLCTLSQSYGCQDNVGAMVVYLNIGEEGCTCEMNGLTLPGPMGFASTTIIKDPPKPTTPSSSSGIASEFSSEMSTSEVSSEVGSTASDEHNTVGLDAGLLPRPERRCSLHPAPTSGVFQRQPSCATFSSNQSDNGLDSDDDQPVEGVITNGSKVEVEVDIHCCRGRDLENSPTLPENSPAPCPEDRSRGSLFGIRRQNSVNSGILLPVSKDRTELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEAPKKKTGYFAAPTQLEPEDQFVIPRDLEEEVKEQMKHHQESRHEPEPSEEDRTELPEEFDTAL", "length": 1355, "header": "tr|E1BMD4-1|E1BMD4_BOVIN Isoform 1 of PH domain leucine-rich repeat-containing protein phosphatase 2 OS=Bos taurus OX=9913 GN=PHLPP2 PE=4 SV=4 CANONICAL=E1BMD4-1" }, "locus": { "chromosome": "18", "start_pos": 39415482, "end_pos": 39354236, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061006.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061006.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053245.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053245.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1157, "start_aa": "Thr", "end_pos": 1157, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1157", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XYE1-1", "protein_name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "gene_name": "PHLPP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLCPTGARCRSSTHLRVATAEPSLTPRAAEVPALPGRGARGSAAAAAAPGGLAVRPAMGEAGPGPKEAPEEDEAAAVGVRDGRAGPRGVVRVLKRNVKRNGSRSCLNRSRFSSRERDWLREDVGRGCVYVYGGDSVAAASSDLRLVLCTVDTPASEICDGEDKKNLFVQLHGDLVRRLEPTEKPLWILYDYLAGLGFDDPVRMQEEAANSDLSCMIRFYSEKPCQVEQLDRILLSGIYNVRKGKTQLHKWAERLVILCGTCLIVSSVKDSHTGKMHILPLVGGKVEEMKRRQYTLAFTSAGAQAQTYHVSFETLAECQRWHRQASTVVSMRLSMVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMRSSGAGSLESLCRFSQLKSLNLSHNRLGEFPVSLCEISTLTELNMSCNGLYHLPSQIGKLLNLQSCWLDGNFLTSLPEELGSLQQLSCLGLSFNNFCELPAICEKLTILDKIAMAGNLLENLDLTVLNRMNHVKSVDLRLNNLKRAAADTLEGNKSVTYMDLRDNQLTDLDLSSLGSLEQLHCERNKLKELTLSGFSLRALYANNNCLTSVSVYPVPGQLTCLELAHNQMQCVPDWACEAKKLEILDMSYNLLVELPSRILSSLSLRKLTVGHNNLQSLPPLLEHIPMEVLDLQHNLLTKLPETLFVKALNLRHLNASANSLESLPSACTGEESLSMLQLLYLTNNNLTDQCIPVLVGHPNLRILHLANNNLQAFPASKLSKLERLEELNLSGNKLKTIPTTVANCKLLHTLIAHSNDISIFPEILHLPHIQIVDLSCNELNEILIPEALPAALQELDLTGNTNLVLEHKTLDIFSHITTLKIDAKPSLTTDSALTSTFWSHGVAEMAGQRNKLCLSSLALGSFAEGMEAVYGMFDGDKNEELPRLLQCTMADVLLEEVQQSDTMFMSNTFLVSHRKLGMAGQKLGSSAVLCYIHHDMADPASPFSLTVANVGTCQAVLCRSGKPLLLSKVFSLEQCTEEAKRIKEQKAIITEDNKVNGVTCCTRMLGCTYLHPWILPKPHVSSIPLTVQDELLLLGNKALWEHLSYTEAVSAVRHLHDPLAAAKKLCTLAQSYGCQDNVGAMVVYLNISEDNCTCEMHGLSLPGPGGFSSTTAKTATPSSSSGIASEFGSELSASEASSEVGSTASDEHNAVGLDGSLLPRQERRCSLHPLLPSSIFQRQPSSATFSSNQSDNGLDSDDEQPVEGVMTNGSKVEVEVDIHCCKGNGLEFEPPALEYSSSAPGVEDDSGLVLIIQRQNSINSTAAHGGVKEKCELQKSPSTCCLYGKKLSNGSIVPLEESLNLIEVATEAPKKKTGYFAAPSQMEPEDQFVVPPDLEEEVKEQMKQHQENGADQEQKEESAVALTEEFDTAL", "length": 1397 }, "evidence": [ { "id": "E1BMD4", "url": "https://omabrowser.org/oma/group/E1BMD4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A254-1", "protein_name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "gene_name": "Phlpp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEVEPVPAGSLEPPEPPEAAAPRRPGGIRVLKRNMKHNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTTSSSSSSSSSSSSSDLHLVLCTVETPASEICAGEGRESLYLQLHGDLVRRLEPTERPLQIVYDYLSRLGFEDPVRIQEEATNPDLSCMIRFYGEKPCQMDHLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILPLVGGKIEEVKRRQHSLAFSSAGAQAQTYHVSFETLAEYQRWQRQASKVVSQRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPVLLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNVLTALPDELGNLQQLTSLGISFNNFSQIPEVLEKLTMLDKVVMAGNRLEILNLGVLTRMNHVKHVDLRMNHLKTVIIENLEGNKHITHMDLRDNQLTDLDLSSLCSLEQLHCERNQLRELTLSGFSLRNLYANWNKLTAVNVYPVPSLLTSLELSRNLLECIPDWACEAKKLEILDISYNLLTEVPMRILSSLSLRKLMVGHNHIHVLPALVEHIPLEVLDVQHNTLSRLPDTLFSKALNLRYLNASANSLESLPSACAGEESLSVLQLLYLTNNLLTDQCIPVLVGHPHLRVLHLANNQLQTFPASKLNKLEQLEELNLSGNKLKAIPTTIANCKRLHTLVAHANNISIFPEILQLPQIQFVDLSCNDLTEILIPETLPATLQDLDLTGNTNLVLEHKTLDMFSHITTLKIDQKPLPTTDSTVTSTFWSHGLAEMAGQRNKLCVSALAMDNFAEGVGAVYGMFDGDRNEELPRLLQCTMADVLLEEVQHSTSDTVFMANTFLVSHRKLGMAGQKLGSSALLCYIRPDTADPTSSFSLTVANVGTCQAVLCRGGKPVPLSKVFSLEHDPEEAQRVKDQKAIITEDNKVNGVTCCTRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYLEAVSAVRHVQDPLAAAKKLCTLAQSYGCQDNVGAMVVYLNIGEEGCTCEMHGLALPGPVGFASTATIKDAPKPTTPSSSSGIASELSSEVSTSEVSSEVGSTASDEHNTVGLETSLLPRPERRCSLHPVPSAGTFQRQPSCATFSSNQSDNGLDSDDDQPVEGVITNGSRVEVEVDIHCCRGRESENSPTLPKNSSYPCSEEHARGLGFGIRRQNSVNSGILLPVNKDKMELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEAPKRKTGYFAAPTQLEPEDQFVVPRDLEDEVKEQMKQHQESRPEPEPREEDRTEPLQEFDTAL", "length": 1359 }, "evidence": [ { "id": "E1BMD4", "url": "https://omabrowser.org/oma/group/E1BMD4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZVD8-1", "protein_name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "gene_name": "PHLPP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKRNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTTTSSSSSSSSSSSDLHLVLCTVETPASEICAGEGRESLYLQLHGDLVRRLEPTERPLQIVYDYLSRLGFDDPVRIQEEATNPDLGCMIRFYGEKPCHMDRLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILPLVGGKIEEVKRRQYSLAFSSAGAQAQTYHVSFETLAEYQRWQRQASKVVSQRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQLHCGRNQLRELTLSGFSLRTLYASSNRLTAVNVYPVPSLLTFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPVRILSSLSLRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLHLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPEILQLPQIQFVDLSCNDLTEILIPEALPATLQDLDLTGNTNLVLEHKTLDIFSHITTLKIDQKPLPTTDSTVTSTFWSHGLAEMAGQRNKLCVSALAMDSFAEGVGAVYGMFDGDRNEELPRLLQCTMADVLLEEVQQSTNDTVFMANTFLVSHRKLGMAGQKLGSSALLCYIRPDTADPASSFSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDPEEAQRVKDQKAIITEDNKVNGVTCCTRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQDPLAAAKKLCTLAQSYGCQDNVGAMVVYLNIGEEGCTCEMNGLTLPGPVGFASTTTIKDAPKPATPSSSSGIASEFSSEMSTSEVSSEVGSTASDEHNAGGLDTALLPRPERRCSLHPTPTSGLFQRQPSSATFSSNQSDNGLDSDDDQPVEGVITNGSKVEVEVDIHCCRGRDLENSPPLIESSPTLCSEEHARGSCFGIRRQNSVNSGMLLPMSKDRMELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEVPKRKTGYFAAPTQMEPEDQFVVPHDLEEEVKEQMKQHQDSRLEPEPHEEDRTEPPEEFDTAL", "length": 1323 }, "evidence": [ { "id": "E1BMD4", "url": "https://omabrowser.org/oma/group/E1BMD4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BXA7-1", "protein_name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "gene_name": "Phlpp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHNGSRTCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTSSSSSSSSSSDLHLVLCTVETPASEICAGEGRESLYLQLHGDLVRRLEPSERPLQIVYDYLSRLGFEDPVRIQEEATNPDLSCMIRFYGEKPCQMDHLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILPLVGGKIEEVKRRQHSLAFSSAGAQAQTYHVSFETLAEYQRWQRQASKVVSQRMSTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLHKFSQLKGLNLSHNKLGLFPVLLCEISTLTELSLSCNGFHDLPSQIGKLLNLQTLSLDGNGLTALPDELGNLRQLTSLGISFNDFRHIPEVLEKLTMLDKVAMAGNRLEVLNLGALTRMSQVKHVDLRMNHLKTVITENMEGNKHITHMDLRDNQLTDLDLSSLCSLEQLHCERNQLRELTLSGFSLRTLYASWNRLTAVNVYPVPSLLTSLELSQNLLECVPDWACEAKKLEILDISHNLLTEVPMRILSSLSLRKLMVGHNHIHVLPALVEHIPLEVLDIQHNTLSRLPDTLFSKALNLRYLNASANSLESLPSACAGEESLSVLQLLYLTSNLLTDQCIPVLVGHPHLRVLHLANNQLQTFPASKLNKLEQLEELNLSGNKLTAIPTTIANCKRLHTLVAHANNISIFPEILQLPQIQFVDLSCNDLTEILIPEALPATLQDLDLTGNTNLVLEHKTLDMFSHITALKIDQKPLPATDSAVTSTFWSHGLAEMAGQRNKLCVSALAMDNFAEGVGAVYGMFDGDRNEELPRLLQCTMADVLLEEVQHSTNDTVFMTNTFLVSHRKLGMAGQKLGSSALLCYIRPDTADPTSSFSLTVANVGMCQAVLCRGGKPVPLSKVFSLEHDPEEAQRVKDQKAIITEDNKVNGVTCCTRLLGCTYLYPWILPKPHIASTPLTIQDELLILGNKALWEHLSYLEAVNAVRHVQDPLAAAKKLCTLAQSYGCQDNVGAMVVYLNIGEEGCTCEMNGLTLPGPVGFASTAALKDTPKPTTPSSSSGIASEFSSEMSTSEVSSEVGSTASDEHNTVGLEASLLPRPERRCSLHPASSAGVFQRQPSCATFSSNQSDNGLDSDDDQPVEGVITNGSRVEVEVDIHCCRGREPESSPPLPKNSSNACSEERARGAGFGIRRQNSVNSGILLPANRDKMELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEAPKRKTGYFAAPTQLEPEDQFVVPRDLEEEVKEQMKQHQEGRPEPEPRGEERTEPLEEFDTAL", "length": 1320 }, "evidence": [ { "id": "E1BMD4", "url": "https://omabrowser.org/oma/group/E1BMD4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BMD4", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BMD4", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BMD4", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BMD4", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "E1BMD4", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BMD4", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "E1BMD4", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BMD4", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1173, "end_pos": 1175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1274, "end_pos": 1276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 706, "end_pos": 708, "annotation": "n_glycosylation_sequon" }, { "start_pos": 880, "end_pos": 882, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEW5-1", "A0AAA9TV14-1", "A0AAA9S745-1", "A0A3Q1MV48-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "F1MBQ1-1", "A0AAA9RTM1-1", "A0AAF6YJP2-1", "P48452-1", "F1MI99-1", "G3N3B3-1", "O62830-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "A6H772-1", "O62829-1", "P61287-1", "A0AAA9U0H6-1", "Q3ZBF9-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q0P594-1", "Q1RMV9-1", "Q2KJ36-1", "Q2PC20-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0A3Q1N224-1", "E1BMD4-1", "A0AAF6DLF7-1", "F1N580-1", "F1MQM7-1", "F1MW60-1", "F1N719-1", "E1BF95-1", "E1BIE7-1", "F1MEZ2-1", "F1MM08-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLF7-1", "F1MI92-1", "A0A3Q1MV48-1", "E1BEW5-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "A0ABI0P1A3-1", "F1MBQ1-1", "A0AAA9RTM1-1", "G3N3B3-1", "A0AAF6YJP2-1", "P48452-1", "O62829-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "Q0P594-1", "A6H772-1", "O62830-1", "P61287-1", "A0AAA9U0H6-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q1RMV9-1", "Q2KJ36-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "E1BIZ2-1", "F1MI99-1", "F1MP34-1", "F1MEZ2-1", "F1MQM7-1", "F1MM08-1", "F1N719-1", "A0AAA9T455-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0AAA9TV14-1", "A0AAA9S745-1", "F1N580-1", "E1BMD4-1", "E1BF95-1", "E1BIE7-1", "A0A3Q1N224-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1MLC5", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] } ] }, { "uniprot_ac": "A0A3Q1MV48", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": 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"O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] } ] }, { "uniprot_ac": "A0AAA9SCR0", "gene_name": "LOC112441582", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCR0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCR0" } ] } ] }, { "uniprot_ac": "A0AAA9SWY4", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] } ] }, { "uniprot_ac": "A0AAA9T455", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": 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"id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] } ] }, { "uniprot_ac": "E1BAB2", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] } ] }, { "uniprot_ac": "E1BBD9", "gene_name": "LOC112445820", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] } ] }, { "uniprot_ac": "E1BEW5", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] } ] }, { "uniprot_ac": "E1BF95", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BF95", "database": 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"E1BMD4", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] } ] }, { "uniprot_ac": "F1MBQ1", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MI92", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MW60", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1N580", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] } ] }, { "uniprot_ac": "F1N719", "gene_name": "PPP5C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] } ] }, { "uniprot_ac": "F6RRD7", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] } ] }, { "uniprot_ac": "G3N3B3", "gene_name": "PPM1N", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] } ] }, { "uniprot_ac": "O62829", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] } ] }, { "uniprot_ac": "O62830", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62830" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62830" } ] } ] }, { "uniprot_ac": "P0C591", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] } ] }, { "uniprot_ac": "P48452", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48452" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48452" } ] } ] }, { "uniprot_ac": "P61287", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P61287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61287" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P61287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61287" } ] } ] }, { "uniprot_ac": "P67774", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P67774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67774" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P67774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67774" } ] } ] }, { "uniprot_ac": "P79126", "gene_name": "PPM1G", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P79126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79126" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P79126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79126" } ] } ] }, { "uniprot_ac": "Q0IID7", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] } ] }, { "uniprot_ac": "Q0IIF0", "gene_name": "ILKAP", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIF0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0IIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIF0" } ] } ] }, { "uniprot_ac": "Q0P594", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0P594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P594" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0P594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P594" } ] } ] }, { "uniprot_ac": "Q17QI2", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QI2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QI2" } ] } ] }, { "uniprot_ac": "Q17QJ3", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] } ] }, { "uniprot_ac": "Q17QM8", "gene_name": "DUSP14", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BA03", "url": "https://www.uniprot.org/uniprotkb/E1BA03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BA03-1", "url": "https://www.uniprot.org/uniprotkb/E1BA03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRITRVQLQPMKTVVRGSSVPTDGYISGLLNDIQKLSVISSNTLRGRSPTSRRRAQSLGLLGDEQWAADPDMYLQSPQSERSDPHGLYLSCNGGAPAGRRQVPWPELQSPRVLPNGLAAKAQSLGPAEFQGATQRCLQLGTCLQSSPTGTSPPTATGRRGTKTARHGPEEARPQSCLVGSAAGRPGGEGSPSPKTQESSLKRRLFRSMFLSAPATAPPSSSKPGPPAQSKPSSSFRPALKGGPSSLVAKAQSLPSDQPVGPFSPLTASDTSSPQKSLRAAPAAGAPPGRSSPAGSPRTRHAQISTSNLYLPQDPAVAKGALAGEDTGVVTHEQFKAALRMVVDQGDPRLLLDSYLKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSYKVSPVLRDFLDRMLVRDPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTSTC", "length": 681, "header": "tr|A0ABI0NJ75-1|A0ABI0NJ75_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=PAK6 PE=3 SV=1 CANONICAL=A0ABI0NJ75-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M0P8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75/entry#A0A3Q1M0P8-1", "sequence": { "sequence": "MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRITRVQLQPMKTVVRGSSVPTDGYISGLLNDIQKLSVISSNTLRGRSPTSRRRAQSLGLLGDEQWAADPDMYLQSPQSERSDPHGLYLSCNGGAPAGRRQVPWPELQSPRVLPNGLAAKAQSLGPAEFQGATQRCLQLGTCLQSSPTGTSPPTATGRRGTKTARHGPEEARPQSCLVGSAAGRPGGEGSPSPKTQESSLKRRLFRSMFLSAPATAPPSSSKPGPPAQSKPSSSFRPALKGGPSSLVAKAQSLPSDQPVGPFSPLTASDTSSPQKSLRAAPAAGAPPGRSSPAGSPRTRHAQISTSNLYLPQDPAVAKGALAGEDTGVVTHEQFKAALRMVVDQGDPRLLLDSYLKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVSPVLRDFLDRMLVRDPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTSTC", "length": 636, "header": "tr|A0A3Q1M0P8-1|A0ABI0NJ75_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=PAK6 PE=3 SV=1 CANONICAL=A0ABI0NJ75-1" }, "locus": { "chromosome": "10", "start_pos": 35894299, "end_pos": 35883404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074191.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074191.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061574.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061574.2" } ] } }, { "isoform_ac": "A0ABI0NJ75-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75/entry#A0ABI0NJ75-1", "sequence": { "sequence": "MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRITRVQLQPMKTVVRGSSVPTDGYISGLLNDIQKLSVISSNTLRGRSPTSRRRAQSLGLLGDEQWAADPDMYLQSPQSERSDPHGLYLSCNGGAPAGRRQVPWPELQSPRVLPNGLAAKAQSLGPAEFQGATQRCLQLGTCLQSSPTGTSPPTATGRRGTKTARHGPEEARPQSCLVGSAAGRPGGEGSPSPKTQESSLKRRLFRSMFLSAPATAPPSSSKPGPPAQSKPSSSFRPALKGGPSSLVAKAQSLPSDQPVGPFSPLTASDTSSPQKSLRAAPAAGAPPGRSSPAGSPRTRHAQISTSNLYLPQDPAVAKGALAGEDTGVVTHEQFKAALRMVVDQGDPRLLLDSYLKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSYKVSPVLRDFLDRMLVRDPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTSTC", "length": 681, "header": "tr|A0ABI0NJ75-1|A0ABI0NJ75_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=PAK6 PE=3 SV=1 CANONICAL=A0ABI0NJ75-1" }, "locus": { "chromosome": "10", "start_pos": 35894299, "end_pos": 35883404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136610.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136610.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104436.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104436.1" } ] } }, { "isoform_ac": "E1BA03-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75/entry#E1BA03-1", "sequence": { "sequence": "MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRITRVQLQPMKAPLSDLTPTLHHEQEAHHTLPPPLPQTVVRGSSVPTDGYISGLLNDIQKLSVISSNTLRGRSPTSRRRAQSLGLLGDEQWAADPDMYLQSPQSERSDPHGLYLSCNGGAPAGRRQVPWPELQSPRVLPNGLAAKAQSLGPAEFQGATQRCLQLGTCLQSSPTGTSPPTATGRRGTKTARHGPEEARPQSCLVGSAAGRPGGEGSPSPKTQESSLKRRLFRSMFLSAPATAPPSSSKPGPPAQSKPSSSFRPALKGGPSSLVAKAQSLPSDQPVGPFSPLTASDTSSPQKSLRAAPAAGAPPGRSSPAGSPRTRHAQISTSNLYLPQDPAVAKGALAGEDTGVVTHEQFKAALRMVVDQGDPRLLLDSYLKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSYKVSPVLRDFLDRMLVRDPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTSTC", "length": 707, "header": "tr|E1BA03-1|A0ABI0NJ75_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=PAK6 PE=3 SV=2 CANONICAL=A0ABI0NJ75-1" }, "locus": { "chromosome": "10", "start_pos": 35894299, "end_pos": 35883404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025396.6", "url": "https://www.ensembl.org/id/ENSBTAT00000025396.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025396.5", "url": "https://www.ensembl.org/id/ENSBTAP00000025396.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:539224", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539224", "resource": "KEGG Pathway" }, { "id": "R-BTA-9013407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013407", "resource": "Reactome", "description": "RHOH GTPase cycle" }, { "id": "R-BTA-9013424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013424", "resource": "Reactome", "description": "RHOV GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ75", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ75", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ75", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ75", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ75", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ75", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ75", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ75", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ], "pmid": "" }, { "name": "regulation of MAPK cascade", "id": "GO:0043408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043408", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ75", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-BTA-9018758", "name": "RHOH binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "Q3ZCJ7-1", "P11181-1", "Q0VBZ0-1", "Q08E52-1", "E1BMP9-1", "F1MY55-1", "A0A3Q1MW77-1", "G3X757-1", "A0A3Q1MEQ8-1", "A0ABI0NJ75-1" ], "evidence": [ { "id": "R-BTA-9018758", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9018758" } ] }, { "id": "R-BTA-9018794", "name": "RHOV binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "F1MC61-1", "A0AAA9RXB5-1", "Q08E52-1", "Q2KJ93-1", "E1BJ31-1", "A5D7F8-1", "Q17QI8-1", "A0ABI0NJ75-1" ], "evidence": [ { "id": "R-BTA-9018794", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9018794" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": 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"evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] } ] }, { "uniprot_ac": "A0A3Q1LWT7", "gene_name": "CAMKK2", 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M0G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0G8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M0G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0G8" } ] } ] }, { "uniprot_ac": "A0A3Q1M1Z0", "gene_name": "ULK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] } ] }, { "uniprot_ac": "A0A3Q1M2U5", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2U5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2U5" } ] } ] }, { "uniprot_ac": "A0A3Q1M334", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] } ] }, { "uniprot_ac": "A0A3Q1M4N6", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4N6", "database": 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"uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { "uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9RXB5", "gene_name": "USP9X", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A0AAA9RXB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXB5" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A0AAA9RXB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXB5" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5D7F8", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BMP9", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P11181", "gene_name": "DBT", "activity": [ { "ec_number": "2.3.1.168", "activity": "(2S)-2-methylbutanoyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = N(6)-{(R)-S(8)-[(2S)-2-methylbutanoyl]dihydrolipoyl}-L-lysyl-[protein] + CoA.", "evidence": [ { "id": "P11181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11181" } ] }, { "ec_number": "2.3.1.168", "activity": "", "evidence": [ { "id": "P11181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11181" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "P11181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11181" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VBZ0", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QI8", "gene_name": "Rhov", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q17QI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QI8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q17QI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QI8" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJ93", "gene_name": "CDC42", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q2KJ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ93" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q2KJ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ93" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": 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"type": "recommended", "evidence": [ { "id": "E1BN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ] }, { "name": "RREB1", "type": "synonym", "evidence": [ { "id": "XP_015315501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015315501" } ] } ], "protein_names": [ { "name": "Ras-responsive element-binding protein 1", "type": "recommended", "evidence": [ { "id": "E1BN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN44/entry#names_and_taxonomy" } ] }, { "name": "ras-responsive element-binding protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015315501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015315501" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RREB1", "url": "https://www.uniprot.org/uniprotkb/E1BN44", "locus": { "chromosome": "23", "start_pos": 48050200, "end_pos": 48110128, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005980", "url": "https://www.ensembl.org/id/ENSBTAG00000005980" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005980", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005980", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "789017", "url": "https://www.ncbi.nlm.nih.gov/gene/789017", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:789017", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789017", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAPDQKV", "url": "https://omabrowser.org/oma/group/DAPDQKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46451", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46451", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46451:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46451:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015315501", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015315501", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3L0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3L0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN44-1", "url": "https://www.uniprot.org/uniprotkb/E1BN44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSSSPIGLEGSDLSSINTMMSAVMSVGKVTENGGSPQSVKSPTKPPGPNRIGRRNQETKEEKSSYNCPLCEKVCTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSSPAAAPPSPLKRRRLSSKRKLSHDVESEKEDPAPAKKMVEDGPLGDAERKAEEVSHCPLCFKEFVCKYGLETHLETHSDNPLRCDVCCVTFRTHRGLLRHNALVHRQLPRDALGRPFIQNNPAIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFICDTCDKAFPMLSSLTLHKQTHVAANQSPDRLQARAPRGDDLDQKVFLAVLGLQHAEDVRPAPAEEPPPDDNQAIQLQALRCQLPQEPGCAGLLSLAPFDAAALGGALAVLPAASDSVKHLALQPFQKGFIIQPDSSIVVKPISGEPAIELADIQQILKMAAAAPPQVGLPPLAKAPAAPLQAVFKHMPPLKPKPLAAPRTVVATSTPPPLVNTQQASPGCVSPSLPPPPLKLLKGTAEAAPGAHLLPPKSGAQLFLQPPRLELPGQAEVKTQLEQDSLLEALLPLSVEAKIKQEIAEGDLKAIVAGPGGKKAPAVRKVLYPCRFCSQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVTSSTPELVDTLCSPETVCRLCGEDLKHYRALRVHMRAHCGRGLGGCPKPRKPFECKECSAAFSAKRNCIHHVLKQHLHVPERDIESYVLAADGLGPANTPAEAPGRTDEGERKPLAAFLEPQNGFLPAGPAQPLPAHVAVKVEPANNLATDFNEPLDFSQKGLALIQVKQENAAAFLSPSAPYDCSMEPIDLSIPKNFRRGDKDSAAPGEAKKPEQEPGSSEQASPGPPACPTLPATLGASGPLEKPGVPAAASSAASPLEAAALPLQGPVQLAVPLYSSALVNSSPLLGSSTLGSPALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVADPGPGGTSGTAAALDGIGGALPKATTDITSPKESSDSPPSANSPEAASPTEQGPAGLSKKRGRKRGARSRARSSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQSAEDDAQDEVAAAPADHNGPSDEEQGSPPEDRLLRAKRNSYANCLQKINCPHCSRVFPWASSLQRHMLTHTGQKPFPCQKCGAFFSTKSNCERHQLRKHGVTACSLRRNGLIPQSKESDGARDSTDSQSDAEASAAGSEVLDLTARELPAPTPEGASEPSPAAAPAREDPPGGAQEEAEQVATEEDLHPEEEDAQPTEEEEGEEECAEEEPAEAADGPEEDTVSNKSLDLNLASTLMGFKLAEGEAGAQDHKHTCHVCGKSFKFLTTLSRHRKAHDREEPGDESAPPREHEGPHPADPEPPAPEPPAEAEVTPDAPAEKQSEAAEGPSDADADGDGEGPAEKRPLEKSDDDKKPKTDTPRSAASKADKRKKVCSVCSKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRVHQKARHAKRHGRDSDREEHAEEDSESESAHSGAHPVSEGEGDAGLHASAHVALTRSRRESLAAKDAGRREERAAARTAGASQAAAGRSTPRAAAAGSPPEPAPQGDPGRESPAGLLQDLLELPGRRPAHPLLPTADSASLLGLE", "length": 1745, "header": "tr|E1BN44-1|E1BN44_BOVIN Isoform 1 of Ras-responsive element-binding protein 1 OS=Bos taurus OX=9913 GN=RREB1 PE=3 SV=3 CANONICAL=E1BN44-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M3L0-1", "url": "https://www.uniprot.org/uniprotkb/E1BN44/entry#A0A3Q1M3L0-1", "sequence": { "sequence": "MTSSSPIGLEGSDLSSINTMMSAVMSVGKVTENGGSPQSVKSPTKPPGPNRIGRRNQETKEEKSSYNCPLCEKVCTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSSPAAAPPSPLKRRRLSSKRKLSHDVESEKEDPAPAKKMVEDGPLGDAERKAEEVSHCPLCFKEFVCKYGLETHLETHSDNPLRCDVCCVTFRTHRGLLRHNALVHRQLPRDALGRPFIQNNPAIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFICDTCDKAFPMLSSLTLHKQTHVAANQSPDRLQARAPRGDDLDQKVFLAVLGLQHAEDVRPAPAEEPPPDDNQAIQLQALRCQLPQEPGCAGLLSLAPFDAAALGGALAVLPAASDSVKHLALQPFQKGFIIQPDSSIVVKPISGEPAIELADIQQILKMAAAAPPQVGLPPLAKAPAAPLQAVFKHMPPLKPKPLAAPRTVVATSTPPPLVNTQQASPGCVSPSLPPPPLKLLKGTAEAAPGAHLLPPKSGAQLFLQPPRLELPGQAEVKTQLEQDSLLEALLPLSVEAKIKQEIAEGDLKAIVAGPGGKKAPAVRKVLYPCRFCSQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVTSSTPELVDTLCSPETVCRLCGEDLKHYRALRVHMRAHCGRGLGGCPKPRKPFECKECSAAFSAKRNCIHHVLKQHLHVPERDIESYVLAADGLGPANTPAEAPGRTDEGERKPLAAFLEPQNGFLPAGPAQPLPAHVAVKVEPANNLATDFNEPLDFSQKGLALIQVKQENAAAFLSPSAPYDCSMEPIDLSIPKNFRRGDKDSAAPGEAKKPEQEPGSSEQASPGPPACPTLPATLGASGPLEKPGVPAAASSAASPLEAAALPLQGPVQLAVPLYSSALVNSSPLLGSSTLGSPALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVADPGPGGTSGTAAALDGIGGALPKATTDITSPKESSDSPPSANSPEAASPTEQGPAGLSKKRGRKRGARSRARSSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQSAEDDAQDEVAAAPADHNGPSDEEQGSPPEDRLLRAKRNSYANCLQKINCPHCSRVFPWASSLQRHMLTHTDSQSDAEASAAGSEVLDLTARELPAPTPEGASEPSPAAAPAREDPPGGAQEEAEQVATEEDLHPEEEDAQPTEEEEGEEECAEEEPAEAADGPEEDTVSNKSLDLNLASTLMGFKLAEGEAGAQDHKHTCHVCGKSFKFLTTLSRHRKAHDREEPGDESAPPREHEGPHPADPEPPAPEPPAEAEVTPDAPAEKQSEAAEGPSDADADGDGEGPAEKRPLEKSDDDKKPKTDTPRSAASKADKRKKVCSVCSKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRVHQKARHAKRHGRDSDREEHAEEDSESESAHSGAHPVSEGEGDAGLHASAHVALTRSRRESLAAKDAGRREERAAARTAGASQAAAGRSTPRAAAAGSPPEPAPQGDPGRESPAGLLQDLLELPGRRPAHPLLPTADSASLLGLE", "length": 1691, "header": "tr|A0A3Q1M3L0-1|E1BN44_BOVIN Computationally mapped isoform of Ras-responsive element-binding protein 1 OS=Bos taurus OX=9913 GN=RREB1 PE=3 SV=1 CANONICAL=E1BN44-1" }, "locus": { "chromosome": "23", "start_pos": 48105718, "end_pos": 48051204, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084410.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084410.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064739.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064739.1" } ] } }, { "isoform_ac": "E1BN44-1", "url": "https://www.uniprot.org/uniprotkb/E1BN44/entry#E1BN44-1", "sequence": { "sequence": "MTSSSPIGLEGSDLSSINTMMSAVMSVGKVTENGGSPQSVKSPTKPPGPNRIGRRNQETKEEKSSYNCPLCEKVCTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSSPAAAPPSPLKRRRLSSKRKLSHDVESEKEDPAPAKKMVEDGPLGDAERKAEEVSHCPLCFKEFVCKYGLETHLETHSDNPLRCDVCCVTFRTHRGLLRHNALVHRQLPRDALGRPFIQNNPAIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFICDTCDKAFPMLSSLTLHKQTHVAANQSPDRLQARAPRGDDLDQKVFLAVLGLQHAEDVRPAPAEEPPPDDNQAIQLQALRCQLPQEPGCAGLLSLAPFDAAALGGALAVLPAASDSVKHLALQPFQKGFIIQPDSSIVVKPISGEPAIELADIQQILKMAAAAPPQVGLPPLAKAPAAPLQAVFKHMPPLKPKPLAAPRTVVATSTPPPLVNTQQASPGCVSPSLPPPPLKLLKGTAEAAPGAHLLPPKSGAQLFLQPPRLELPGQAEVKTQLEQDSLLEALLPLSVEAKIKQEIAEGDLKAIVAGPGGKKAPAVRKVLYPCRFCSQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVTSSTPELVDTLCSPETVCRLCGEDLKHYRALRVHMRAHCGRGLGGCPKPRKPFECKECSAAFSAKRNCIHHVLKQHLHVPERDIESYVLAADGLGPANTPAEAPGRTDEGERKPLAAFLEPQNGFLPAGPAQPLPAHVAVKVEPANNLATDFNEPLDFSQKGLALIQVKQENAAAFLSPSAPYDCSMEPIDLSIPKNFRRGDKDSAAPGEAKKPEQEPGSSEQASPGPPACPTLPATLGASGPLEKPGVPAAASSAASPLEAAALPLQGPVQLAVPLYSSALVNSSPLLGSSTLGSPALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVADPGPGGTSGTAAALDGIGGALPKATTDITSPKESSDSPPSANSPEAASPTEQGPAGLSKKRGRKRGARSRARSSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQSAEDDAQDEVAAAPADHNGPSDEEQGSPPEDRLLRAKRNSYANCLQKINCPHCSRVFPWASSLQRHMLTHTGQKPFPCQKCGAFFSTKSNCERHQLRKHGVTACSLRRNGLIPQSKESDGARDSTDSQSDAEASAAGSEVLDLTARELPAPTPEGASEPSPAAAPAREDPPGGAQEEAEQVATEEDLHPEEEDAQPTEEEEGEEECAEEEPAEAADGPEEDTVSNKSLDLNLASTLMGFKLAEGEAGAQDHKHTCHVCGKSFKFLTTLSRHRKAHDREEPGDESAPPREHEGPHPADPEPPAPEPPAEAEVTPDAPAEKQSEAAEGPSDADADGDGEGPAEKRPLEKSDDDKKPKTDTPRSAASKADKRKKVCSVCSKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRVHQKARHAKRHGRDSDREEHAEEDSESESAHSGAHPVSEGEGDAGLHASAHVALTRSRRESLAAKDAGRREERAAARTAGASQAAAGRSTPRAAAAGSPPEPAPQGDPGRESPAGLLQDLLELPGRRPAHPLLPTADSASLLGLE", "length": 1745, "header": "tr|E1BN44-1|E1BN44_BOVIN Isoform 1 of Ras-responsive element-binding protein 1 OS=Bos taurus OX=9913 GN=RREB1 PE=3 SV=3 CANONICAL=E1BN44-1" }, "locus": { "chromosome": "23", "start_pos": 48105718, "end_pos": 48051204, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044565.5", "url": "https://www.ensembl.org/id/ENSBTAT00000044565.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042051.4", "url": "https://www.ensembl.org/id/ENSBTAP00000042051.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1083, "start_aa": "Thr", "end_pos": 1083, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1083", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1333, "start_aa": "Thr", "end_pos": 1333, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1333", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:789017", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789017", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K4K0-1", "protein_name": "Ras-responsive element-binding protein 1", "gene_name": "Rreb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSNPPTGLEGSDLSSVNTMMSAVMSISSVTENGGSPQGIKSPMKPPGPNRIGRRNQETKEEKSSYNCPLCEKVCTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDTNSTTAAAPPSPLKRRRLSSKRKLSHDAESEREDPGPAKKTVEDGQSSGLDKMADETFHCPVCFKEFVCKYGLETHMETHSDNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLSSLILHRQTHIPADQGREKLQTKTLAADTLDQKVFLAFLGLQHTKDVKPAPAEELLPDDSHTIQLQTLKCQLPQDPGCTNVLSLSPFEAASLGGSLTVLPATKENMKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPLSKAPATPLQAIFKHMPPLKPKPLVAPRTVVAASTPPPLINAQQASPGCISPSLPPQSLKFLKGSVEAVSSAHLLQSKSGIQPNTSTQLFLQQPGVELPGQAEMKAQLEQDSIIEALLPLNMEAKIKQEITEGDLKAIMTGPSGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIQYVSSSTAELVDALCSPETVCRLCGEDLKHYRALRIHMRTHCSRGLGGCHKGRKPFECKECNAAFAAKRNCIHHILKQHLHVPEKDIESYVLATDAGLGPADTAAEASSREESSCVTFAECKPLTTFLEPQNGFLHSSPTQPLPSHISVKLEPASSFATDFNEPLDFSQKGLALVQVKQENMSSLLNSSSSSALYDCSMEPIDLSIPKSGKRGDKDTVVSSDAKKPEPEAGKAEQLSPHPPPCPTLSVTVEPKGSLDNPAGTVVAVTTAAKLEPHTQPLQGSVQLAVPIYSSALISNAPLLGSSALLNSASLLRPLRPKPPLLLPKPAMTEELPPLASIAQIISSVSSAPTLLKTKAADPGPSSTSSNAVATDSPGGSIPKASPSPTDIPSSREPTDPAPTASSPEEASPPEQGPAASSRKRGRKRGMRNRPLPNSSAVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDTQEEVAGTPADHRGPTEEEQGSSAEDRLLRAKRNSYANCLQKINCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRNGLIPPKEGDVGSHDSTDSQSDTDTLTTPGEVLDLTARDKEQPTSEGASELSPATQDLTETEAKAEAAPPEEEEEEKGTEENPEPELECRVEESSGDADAPEEDTASNQSLDLDFATKMMDFKLAESEAGAVDSQGPAQQEPKHACNTCGKNFKFLSTLSRHRKAHGCQEPKEEEEAPSLENESLGRAVEGPSPSPEPEETPAESSATDPTAGTGEASGERQNEDTESPSDGEGTAEKRGDSDRRPKTDSPKSMASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHSKHHGKDSDKDERAEEGSEDESTHSANNPASENEAESAPSTSNHVAITRSRKESLANSGKECGREEKAIAEQATEPSAPKEPGSPGETDPQSPAAIVQDLLELCGTRPAPILAATDGASQLLGME", "length": 1751 }, "evidence": [ { "id": "E1BN44", "url": "https://omabrowser.org/oma/group/E1BN44/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YDK8-1", "protein_name": "Ras-responsive element-binding protein 1", "gene_name": "RREB1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MYCAAKATLWRRSAGSAGACVPFPLSCRLSPRLQVLEGATEEEAEEPDATKPTTLSEETSKQEESLSQSGDSNEEKQLETLNSYKVTPSSPNSSDGADLSSIDAMMSAVMNVGKIAENGGTSQTVKSPSKSPAPNRIGRRNQETKEEKSSYTCPLCEKICTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCSVCGQSFTTNGNMHRHMKIHEKDPNSTASTTPPSPLKRKRLSSKRKFSQDAEMDREERTPAKKVVEDGQYGEGDRKEDDAYHCPVCFKDFFCKYALESHMETHPDNSLRCDICCITFRTHRGLLRHNAVIHKQLPRDPTGKPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQVWCETNLRRCISEFHRFICETCNKAFPMLLALKLHTETHVMDQGRDKHKLQSTSLPSENPDQKAFMASLGLQYTKDIKPVKQEDDTQDEVQEMRLRALKSNLPQEPGSTGLLSLSPLEAATMGGPFSVLPPTKENIKLLSLQPFQKGFIIQPDSSIVVKPISNESAIELADIQQILKMASSAPPQISLPPLSKAPSVPVQSIFKHMPPLKPKPLVTPRTVVATSTPPPLISAQQASPGCISPSLPPPPLRLIKNSVETSSNSHLSQPGAKSSPSSQLLLQPKVEPLTQHEMKTQLEQDSIIEALLPLNMEAKIKQEVTEGDLKAIIAGAANKKAPTMRKVLYPCRFCDQVFAFSGVLRAHIRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKVTRKDIEKNIEYVTSNAAEMVDAFCSPDTVCKLCGEDLKHYRALRIHMRTHSGCQKKKPFECKECGTAFSAKRNCIHHILKQHLHVQEREIENYILVVDCSAQESHTDAPLLEDSTYMDCKPITPFLEPQNGFLLGTSSHVPIKLEPMGNFPMDFDEPLDFSQKSKNLSAVQVKQENLLVSSPLSFYDCSMEPIDLSIPKVLKRDNDIPGEARNQELASSVITDNAYNCQQCPLGFGANGNSEKNRAVGHPQPLKGSLHLTVPIISPALLGNSALLRPLRPKPPPQPLLPKPPVTKELPPLASIAQIISSVSSAPALLKTEAADASPKAASSSTGCDKSGNAKAKMTIVTAIQRDSNLPSDLTQACDPEPSPIADTGLTKKRGRKKGTKNKPKLSSGVDLESSGEFASIEKMLATTDTNKFSPFLQSTDNFKEESGQNGTSEDEKETPEDKLLRGKRNTYSDCPQKITCPYCPRVFSWASSLQRHMLTHTDSQADTEAPATGGEVLDLTSCEKEQPEEVSELPGSECSPQEEQKADSPPAEEDAEEKADEYEEGPEEDSVSNKSLDLNFASKLMDFKLAESDQSAGSSSQTERKHACDVCGKTFKFAGTLSRHKKAHIREDRKDERSSEDESKSIQDDAGAPSMQDSGLEQEESPMDLKVVESPLDCEATGKENEESESISEGEGTERKSTEKSSDDKIPKTDEAKSTAKADKRKKVCTVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKVKNTRNHGKESDKEETQSRCGEDSENESSHSGTNPISENECDFAGVVGSHPSGTRSRKESLVGAAKDVPCEEERPSGQGATADLVEPAKSTQKQPAKDQEPRGSSELERPSGFIQDLLEMHNKKSPMNHILASADSTPQLLGVE", "length": 1719 }, "evidence": [ { "id": "E1BN44", "url": "https://omabrowser.org/oma/group/E1BN44/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HD91-1", "protein_name": "Ras-responsive element-binding protein 1", "gene_name": "Rreb1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"length": 1748 }, "evidence": [ { "id": "E1BN44", "url": "https://omabrowser.org/oma/group/E1BN44/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3UH06-1", "protein_name": "Ras-responsive element-binding protein 1", "gene_name": "Rreb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1700 }, "evidence": [ { "id": "E1BN44", "url": "https://omabrowser.org/oma/group/E1BN44/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92766-1", "protein_name": "Ras-responsive element-binding protein 1", "gene_name": "RREB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSSSPAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASLGGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISPSLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDSIIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIESYVLAADGLGPAEAPAAEASGRGEDSGCAALGDCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPLDFSQKGLALVQVKQENISFLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPEEEAGSSEQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAVPIYSSALVSSPPLVGSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVADPGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAASPTEQGPAGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASATKDCSHREEKVTAGWPSEPGQGDLNPESPAALGQDLLEPRSKRPAHPILATADGASQLVGME", "length": 1687 }, "evidence": [ { "id": "E1BN44", "url": "https://omabrowser.org/oma/group/E1BN44/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "positive regulation of developmental process", "id": "GO:0051094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051094", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "positive regulation of substrate adhesion-dependent cell spreading", "id": "GO:1900026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900026", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "positive regulation of lamellipodium morphogenesis", "id": "GO:2000394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000394", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell migration", "id": "GO:0010634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010634", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "positive regulation of brown fat cell differentiation", "id": "GO:0090336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090336", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "positive regulation of wound healing, spreading of epidermal cells", "id": "GO:1903691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903691", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "positive regulation of mammary gland epithelial cell proliferation", "id": "GO:0033601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033601", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BN44", "url": "https://www.uniprot.org/uniprotkb/E1BN44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, "end_pos": 1017, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1406, "end_pos": 1408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN44" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 93, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1083, 1333 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1015, "end_pos": 1017 }, { "start_pos": 1406, "end_pos": 1408 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 342, "end_pos": 344 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNH9-1", "uniprot_ac": "E1BNH9", "uniprot_id": "E1BNH9_BOVIN", "mass": { "chemical_mass": 207709.0, "monoisotopic_mass": 207709.0 }, "refseq": {}, "gene_names": [ { "name": "OBSL1", "type": "recommended", "evidence": [ { "id": "E1BNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ] } ], "protein_names": [ { "name": "Obscurin-like protein 1", "type": "recommended", "evidence": [ { "id": "E1BNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Acts as a regulator of the Cul7-RING(FBXW8) ubiquitin-protein ligase, playing a critical role in the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain. Required to localize CUL7 to the Golgi apparatus in neurons.", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9#function" }, { "database": "UniProtKB", "id": "ARBA00057297", "url": "https://www.uniprot.org/uniprotkb/ARBA00057297#function" }, { "database": "UniProtKB", "id": "A0A3Q1M6J4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6J4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OBSL1", "url": "https://www.uniprot.org/uniprotkb/E1BNH9", "locus": { "chromosome": "2", "start_pos": 107478722, "end_pos": 107501010, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040338", "url": "https://www.ensembl.org/id/ENSBTAG00000040338" } ] } } ], "crossref": [ { "id": "ENSBTAG00000040338", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000040338", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "511087", "url": "https://www.ncbi.nlm.nih.gov/gene/511087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KAEVRWY", "url": "https://omabrowser.org/oma/group/KAEVRWY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M6J4", "url": "https://www.orthodb.org/?gene=A0A3Q1M6J4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MD24", "url": "https://www.orthodb.org/?gene=A0A3Q1MD24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BNH9", "url": "https://www.orthodb.org/?gene=E1BNH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35971", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35971", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35971:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35971:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M6J4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MD24", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MD24-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH9-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAGSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPTVVWEKGGQQLAASDRLSFPVDGAEHCLLLSGALPTDAGVYVCRARNSAGEAYAAAAVTVLEPPAHEPEPQLAERPLPPPGAGEGAPVFLTGPRSQWVLRGAEVVLECQVGGLPAPTLYWEKDGMALDEVWDSSHFSLEPGRAGAGAGASLALRILAARLPDSGVYVCHARNAHGHARAGALLQVQQTPESPPEDPDEAPTPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFSRPLQDVEGREHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGVYLCEMRGRVRTVANVTVKGPILKRLPRKLDVFEGENAVLLVETREAGVEGRWSRDGEDLPATCQSSSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCIKHNPPGPPVLAEMFKGHRNTVLLTWKPPDPTPETPFIYRLERQEVGSEDWVQCFSIEKAGAVEVPGDCVPTEGDYRFRVCTVSEHGRSPHVVFHGSAHLVPTAHLVAGLEEVQVYDGEDAVFSLDLSTVIQGTWFLNGEELKSNEPEGQVGPGPLRYRVEQHGLQHRLILQAVRHQDSGALIGFSCPGVQDSAALTIQESPVHILSPQDKVSLTFTTSDRVVLTCELSRVDFPASWYKDGQQVEESESLVVKMDGRKHRLILPEAQVQDSGEFECRTEGISAFFSVTVQDPPVHIVAPREHVFVHAITSECVMLTCEVDREDAPVHWFKDGQEVEESDFVLLESEGPHRRLVLPSAQPSVGGEFQCVAGDERAYFTVTITDVSSWIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRILYPRDEVTLVAVSLECVVLMCELSREDAPVRWYKDGLEVEESEALVLESDGPHRRLVLPAAQPQDGGEFVCDAGDDSAFYTVTVTAPPERIVHPAARSLDLQFRAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRDEAVTFNISLAEPPVQFLAPEAAPGPLCVAPGEPVVLSCELSRAGALVFWSHNGKPVQTGEGLELRAEGPRRVLCIRAADLAHAGLYTCQCGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELAVRLSGPGGPVRWYKDGERLASQGRVHLEQDGARQVLRVRGARSRDAGEYLCDTPQDSRIFLVSVEEPPLVKLISELTPLTVHEGDDATFRCEVSPPDADITWLRNGVVVTPGPQLEMTQNGSSRTLTVRSCRLEDAGTVTARAGGTSTSARLHVRETELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWMRGGAPLPPDSRLSTAQDGHIYRLFIHCVVLADQGTYGCESHHDRTLARLSVRPKQLRVLQPLEEVTIIEGGSATFQLELSQEGVTGEWARGGVRLQPGPKCQIQAEGHAHHLVLSGLGLADSGCISFTADTLRCAARLTVREAPVTIVRGLQDLEVTEGDTATFECALSQTLADVTWEKDGQPLTPSARLRLQALGTRRLLQLRRCSPLDAGTYSCVVGMARTGPVHLVVRERKVSVLSELRSVSAREGDGATFECTVSEVETAGSWELGGRPLRPGGRVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSVAQLEVEALPLQMLRRPPREKTVLVCRRAVLEVTVSRPGGQVCWLREGAELCPGDKYQLRSHGPTHSLVIHDVRPEDQGTYCCQAGQDSAYTRLLVEGDATLST", "length": 1901, "header": "tr|E1BNH9-1|E1BNH9_BOVIN Isoform 1 of Obscurin-like protein 1 OS=Bos taurus OX=9913 GN=OBSL1 PE=4 SV=3 CANONICAL=E1BNH9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M6J4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH9/entry#A0A3Q1M6J4-1", "sequence": { "sequence": "MKAGSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPTVVWEKGGQQLAASDRLSFPVDGAEHCLLLSGALPTDAGVYVCRARNSAGEAYAAAAVTVLEPPAHEPEPQLAERPLPPPGAGEGAPVFLTGPRSQWVLRGAEVVLECQVGGLPAPTLYWEKDGMALDEVWDSSHFSLEPGRAGAGAGASLALRILAARLPDSGVYVCHARNAHGHARAGALLQVQQTPESPPEDPDEAPTPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFSRPLQDVEGREHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGVYLCEMRGRVRTVANVTVKGPILKRLPRKLDVFEGENAVLLVETREAGVEGRWSRDGEDLPATCQSSSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCIKHNPPGPPVLAEMFKGHRNTVLLTWKPPDPTPETPFIYRLERQEVGSEDWVQCFSIEKAGAVEVPGDCVPTEGDYRFRVCTVSEHGRSPHVVFHGSAHLVPTAHLVAGLEEVQVYDGEDAVFSLDLSTVIQGTWFLNGEELKSNEPEGQVGPGPLRYRVEQHGLQHRLILQAVRHQDSGALIGFSCPGVQDSAALTIQESPVHILSPQDKVSLTFTTSDRVVLTCELSRVDFPASWYKDGQQVEESESLVVKMDGRKHRLILPEAQVQDSGEFECRTEGISAFFSVTVQDPPVHIVAPREHVFVHAITSECVMLTCEVDREDAPVHWFKDGQEVEESDFVLLESEGPHRRLVLPSAQPSVGGEFQCVAGDERAYFTVTITDVSSWIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRILYPRDEVTLVAVSLECVVLMCELSREDAPVRWYKDGLEVEESEALVLESDGPHRRLVLPAAQPQDGGEFVCDAGDDSAFYTVTVTAPPERIVHPAARSLDLQFRAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRDEAVTFNISLAEPPVQFLAPEAAPGPLCVAPGEPVVLSCELSRAGALVFWSHNGKPVQTGEGLELRAEGPRRVLCIRAADLAHAGLYTCQCGAAPGAPSLSFTVQVAEPPLVKLISELTPLTVHEGDDATFRCEVSPPDADITWLRNGVVVTPGPQLEMTQNGSSRTLTVRSCRLEDAGTVTARAGGTSTSARLHVRETELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWMRGGAPLPPDSRLSTAQDGHIYRLFIHCVVLADQGTYGCESHHDRTLARLSVRPKQLRVLQPLEEVTIIEGGSATFQLELSQEGVTGEWARGGVRLQPGPKCQIQAEGHAHHLVLSGLGLADSGCISFTADTLRCAARLTVREAPVTIVRGLQDLEVTEGDTATFECALSQTLADVTWEKDGQPLTPSARLRLQALGTRRLLQLRRCSPLDAGTYSCVVGMARTGPVHLVVRERKVSVLSELRSVSAREGDGATFECTVSEVETAGSWELGGRPLRPGGRVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSVAQLEVEALPLQMLRRPPREKTVLVCRRAVLEVTVSRPGGQVCWLREGAELCPGDKYQLRSHGPTHSLVIHDVRPEDQGTYCCQAGQDSAYTRLLVEGS", "length": 1804, "header": "tr|A0A3Q1M6J4-1|E1BNH9_BOVIN Computationally mapped isoform of Obscurin-like protein 1 OS=Bos taurus OX=9913 GN=OBSL1 PE=4 SV=2 CANONICAL=E1BNH9-1" }, "locus": { "chromosome": "2", "start_pos": 107500811, "end_pos": 107478852, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085439.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085439.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065612.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065612.2" } ] } }, { "isoform_ac": "A0A3Q1MD24-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH9/entry#A0A3Q1MD24-1", "sequence": { "sequence": "MKAGSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPTVVWEKGGQQLAASDRLSFPVDGAEHCLLLSGALPTDAGVYVCRARNSAGEAYAAAAVTVLEPPAHEPEPQLAERPLPPPGAGEGAPVFLTGPRSQWVLRGAEVVLECQVGGLPAPTLYWEKDGMALDEVWDSSHFSLEPGRAGAGAGASLALRILAARLPDSGVYVCHARNAHGHARAGALLQVQQTPESPPEDPDEAPTPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFSRPLQDVEGREHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGVYLCEMRGRVRTVANVTVKGPILKRLPRKLDVFEGENAVLLVETREAGVEGRWSRDGEDLPATCQSSSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCIKHNPPGPPVLAEMFKGHRNTVLLTWKPPDPTPETPFIYRLERQEVGSEDWVQCFSIEKAGAVEVPGDCVPTEGDYRFRVCTVSEHGRSPHVVFHGSAHLVPTAHLVAGLEEVQVYDGEDAVFSLDLSTVIQGTWFLNGEELKSNEPEGQVGPGPLRYRVEQHGLQHRLILQAVRHQDSGALIGFSCPGVQDSAALTIQESPVHILSPQDKVSLTFTTSDRVVLTCELSRVDFPASWYKDGQQVEESESLVVKMDGRKHRLILPEAQVQDSGEFECRTEGISAFFSVTVQDPPVHIVAPREHVFVHAITSECVMLTCEVDREDAPVHWFKDGQEVEESDFVLLESEGPHRRLVLPSAQPSVGGEFQCVAGDERAYFTVTITDVSSWIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTESYQSQDSSNNNPELCILLKKPKTRRLWSRFPPWRRTAGAE", "length": 1025, "header": "tr|A0A3Q1MD24-1|E1BNH9_BOVIN Computationally mapped isoform of Obscurin-like protein 1 OS=Bos taurus OX=9913 GN=OBSL1 PE=4 SV=2 CANONICAL=E1BNH9-1" }, "locus": { "chromosome": "2", "start_pos": 107500811, "end_pos": 107491706, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087103.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087103.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068801.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068801.2" } ] } }, { "isoform_ac": "E1BNH9-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH9/entry#E1BNH9-1", "sequence": { "sequence": "MKAGSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPTVVWEKGGQQLAASDRLSFPVDGAEHCLLLSGALPTDAGVYVCRARNSAGEAYAAAAVTVLEPPAHEPEPQLAERPLPPPGAGEGAPVFLTGPRSQWVLRGAEVVLECQVGGLPAPTLYWEKDGMALDEVWDSSHFSLEPGRAGAGAGASLALRILAARLPDSGVYVCHARNAHGHARAGALLQVQQTPESPPEDPDEAPTPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFSRPLQDVEGREHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGVYLCEMRGRVRTVANVTVKGPILKRLPRKLDVFEGENAVLLVETREAGVEGRWSRDGEDLPATCQSSSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCIKHNPPGPPVLAEMFKGHRNTVLLTWKPPDPTPETPFIYRLERQEVGSEDWVQCFSIEKAGAVEVPGDCVPTEGDYRFRVCTVSEHGRSPHVVFHGSAHLVPTAHLVAGLEEVQVYDGEDAVFSLDLSTVIQGTWFLNGEELKSNEPEGQVGPGPLRYRVEQHGLQHRLILQAVRHQDSGALIGFSCPGVQDSAALTIQESPVHILSPQDKVSLTFTTSDRVVLTCELSRVDFPASWYKDGQQVEESESLVVKMDGRKHRLILPEAQVQDSGEFECRTEGISAFFSVTVQDPPVHIVAPREHVFVHAITSECVMLTCEVDREDAPVHWFKDGQEVEESDFVLLESEGPHRRLVLPSAQPSVGGEFQCVAGDERAYFTVTITDVSSWIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRILYPRDEVTLVAVSLECVVLMCELSREDAPVRWYKDGLEVEESEALVLESDGPHRRLVLPAAQPQDGGEFVCDAGDDSAFYTVTVTAPPERIVHPAARSLDLQFRAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRDEAVTFNISLAEPPVQFLAPEAAPGPLCVAPGEPVVLSCELSRAGALVFWSHNGKPVQTGEGLELRAEGPRRVLCIRAADLAHAGLYTCQCGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELAVRLSGPGGPVRWYKDGERLASQGRVHLEQDGARQVLRVRGARSRDAGEYLCDTPQDSRIFLVSVEEPPLVKLISELTPLTVHEGDDATFRCEVSPPDADITWLRNGVVVTPGPQLEMTQNGSSRTLTVRSCRLEDAGTVTARAGGTSTSARLHVRETELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWMRGGAPLPPDSRLSTAQDGHIYRLFIHCVVLADQGTYGCESHHDRTLARLSVRPKQLRVLQPLEEVTIIEGGSATFQLELSQEGVTGEWARGGVRLQPGPKCQIQAEGHAHHLVLSGLGLADSGCISFTADTLRCAARLTVREAPVTIVRGLQDLEVTEGDTATFECALSQTLADVTWEKDGQPLTPSARLRLQALGTRRLLQLRRCSPLDAGTYSCVVGMARTGPVHLVVRERKVSVLSELRSVSAREGDGATFECTVSEVETAGSWELGGRPLRPGGRVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSVAQLEVEALPLQMLRRPPREKTVLVCRRAVLEVTVSRPGGQVCWLREGAELCPGDKYQLRSHGPTHSLVIHDVRPEDQGTYCCQAGQDSAYTRLLVEGDATLST", "length": 1901, "header": "tr|E1BNH9-1|E1BNH9_BOVIN Isoform 1 of Obscurin-like protein 1 OS=Bos taurus OX=9913 GN=OBSL1 PE=4 SV=3 CANONICAL=E1BNH9-1" }, "locus": { "chromosome": "2", "start_pos": 107500811, "end_pos": 107479065, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000060992.4", "url": "https://www.ensembl.org/id/ENSBTAT00000060992.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053524.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053524.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1135, "start_aa": "Thr", "end_pos": 1135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1135", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1400, "start_aa": "Thr", "end_pos": 1400, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1400", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 242, "start_aa": "Thr", "end_pos": 242, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr242", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 544, "start_aa": "Thr", "end_pos": 544, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr544", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3YYU8-1", "protein_name": "Obscurin-like protein 1", "gene_name": "Obsl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKAGSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPTVVWEKGGQQLVASERLSFPEDGAEHGLLLSGALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPAPEPEPESSECPLPTPGTGEGAPKFLTGPQSQWVLRGEEVVLTCQVGGLPEPKLYWEKDGMALDEVWDSSHFKLEPGRGASDEGASLTLRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPRESPPQDPDENPKPVLEPLKGAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHLEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIVVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGAVRRLVIHKLKADDDGVYLCEMRGRVRTVANVTVKGPILKRLPRKLDVLEGENAVLLVETQEAGVQGCWSRDGEDLPDTCQSSCGHMHALVLPGVTREDAGEITFSLGNSRTTTLLRVKCVKHSPPGPPVMVEMFKGQKNKVLLTWKPPEPPPETSFIYRLERQEVGSDDWIQCFSIEKAGAVEVPGDCVPTEGDYHFRICTVSEHGRSPHVVFNGSAHLVPTARLVSGLEDVQVYDGEDAVFSLDLSAIIQGSWFLNGEQLQSNEPEGQVEPGALRYRIEQKGLQHRLILQAVKHRDSGALVGFSCPGVQDSAALTIQESSVHILSPQDKVSLTFTTSERVVLTCELSRVDFPATWYKDGQKVEESESLIVKTEGRKHRLILPEAQVRDSGEFECRTEGVSAFFGVTVQDPPVHIVNPQEHVFVHAITSECVRLTCEVDREDTTVHWYKDGQEVEESDIIVLENKGPHHRLVLPAARPSDGGEFQCVAGDERAYFTVTITDVFSWIVYPSSEVHVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLEKEDTIRRLVLPSVQLEDSGEYLCEIHDESASFTITVTEPPVRIIYPQDEVTLHAVSLECVVLTCELSREDAPVRWYKDGLEVEESEALVLQSDGPRRRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPAARSLDLQFGAPGHVELRCEVAPAGSQVRWYKDGLEVEVSDALQLGAEGPARTLTLPHAQPEDAGEYVCETRDEAVTFNVSLAELPVQFLAPEAAPNPLCVVPGEPVVLSCELSRASAQVFWSHNGSPVQQGEGLELRAEGPRRILCIQAADLAHTGVYTCQSGASPGAPSLSFNVQVAELPPVKLVSELTPLTVHEGDDATFQCEVSPPDAEVTWLRNGAVITAGPQLEMVQNGSSRTLIIRGCQLKDAGTVTARAGAADTSARLHVRETELLFLRRLQDVRAEEGQDVHLEVETGRVGAAGTVRWIRGGEPLPLDSRLTTAQDGHVHRLSIHGVLLTDQGTYGCESRHDRTLARLSVRPRQLRELRPLEDVTVHEGGSATFQLELSQEGVTGEWAQGGVRLHPGPKCHIQSEGRTHRLVLSGLGLADSGCVSFTADTLRCAARLTVREVPVTIVQGPQDLEVTEGDTATFECELSQTLADVIWEKDGQALSLSPRLRLQALGTRRLLLLRRCCSSDAGTYSCVVGTARSEPARLTVREREVSVLRELRSVSAREGDGATFECTVSETEITGRWELGGRALRPGGRVRIRQEGKKHILVLSELRTEDTGEVCFQAGPAQSLARLEVEALPLQMCRRPPREKTVLVNRRAVLEVTVSRPGGHVCWMREGVELCPGNKYETRRHGTTHSLVIHDVRPEDQGTYSCQAGQDSADTQLLVDGD", "length": 1804 }, "evidence": [ { "id": "E1BNH9", "url": "https://omabrowser.org/oma/group/E1BNH9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZZ80-1", "protein_name": "Obscurin-like protein 1", "gene_name": "Obsl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPTVLWEKGGQQLVASERLSFPEDGAEHGLLLSGALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPAPEPEPQSSECPPPPPGTGEGAPVFLTGPQSQWVLRGAEVVLTCQVGGLPEPKLYWEKDGMALDEVWDSSHYTLEPDRGASDGGASLTLRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPHENPPQDPDEPPVRVIEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHLEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIVVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLVIHRLKADDDGVYLCEMRGRVRTVANVTVKGPILKRLPRKLDVLEGENAVLLVETQEAGVQGCWSRDGEELPATCQSSCGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCVKHSPPGPPVLVEMFKGQKNTVLLTWKPPEPPPETSFIYRLERQEVGSEDWIQCFSIEKAGAVEVPGDCVPTEGDYRFRICTVSEHGRSPHVVFNGSAHLVPTARLVSGLEDVQVYDGEDAVFSLDLSTIIQGSWFLNGELLKNDEAEGQVEPGALRYRIEQKGLQHRLILQTVKHQDNGALVGFICPGVQDSAALSIQESPVHILSPQDKVLLTFTTSERVVLTCELSRVDFPATWYKDGQKVEESESLVVKMDGRKHRLILPEAQVRDSGEFECRTEGISAFFSVTVQDPPVHIVDPQEHVFVHAITSESVMLTCEVDREDAAVHWYKDGQEVEESAVIVLEKEGPRHRLVLPAAQPSDGGEFQCVVGDERAYFTVTITDVSSWIVYPNGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVLESPALLLEKEDTIRRLVLPSVQLEDSGEYLCEIHDESASFTITVTEPPVRIIYPQDEVTLHAVSLECVVLTCELSRVDAPVRWYKDGLEVEETEALVLQSDGPRRRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPVARSLDLQFGAPGHVELRCEVAPAGSQVRWYKDGLEVEVSDALQLGAEGPARTLTLPHAQPEDAGEYVCETRDEAVTFNVSLAELPVQFLAPEAVPNPLCVVPGEPVMLSCELSRASAHVSWSHNGNPVKQGEGLELRAEGPRRILCIQAADLAHTGVYTCQSGTAPGAPSLSFNVQVAEPPPVKLVSELTPLTVHEGDDATFQCEVSPPDAEVTWLRNGAIVTPGPQLEMVHSGSSRTLIIRGCQLKDAGTVTARAGATDTSARLHVRETELLFLRRLQDVRAEEGQDVYLEVETGRVGAPGAVRWLRGGEPLPLDSRLTTAQDGHVHRLSIHGVLLTDQGTYGCESHHDRTLARLSVRPRQLRELRPLEDVTVHEGGSATFQLELSQEGVTGEWAQGGVRLHPGPKCHIHSEGRTHCLVLSGLGLADSGCISFTADTLRCAARLTVREVPVTIVQGPQDLEVTEGDTATFECELSQTLADVIWEKDGQALSLSPRLRLQSLGTRRLLLLRRCSSSDAGTYCCAVGTARSGPARLTVREREVSVLGELRSLSAREGDSATFECTVSESETTGRWELGGRALRPGGRVRIRQEGKKHILVLSELRTEDTGEVCFQAGPAQSLARLEVEALPLQMCRRPPREKTVLVDRRAVLEVTVSRPGGHVCWMREGVELCPGSKYEMRSHGTTHSLVIHDVRPEDQGTYSCQAGQDSADTQLLVEGDD", "length": 1805 }, "evidence": [ { "id": "E1BNH9", "url": "https://omabrowser.org/oma/group/E1BNH9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75147-3", "protein_name": "Obscurin-like protein 1", "gene_name": "OBSL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVANVTVKGPILKRLPRKLDVLEGENAVLLVETLEAGVEGRWSRDGEELPVICQSSSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCVKHSPPGPPILAEMFKGHKNTVLLTWKPPEPAPETPFIYRLERQEVGSEDWIQCFSIEKAGAVEVPGDCVPSEGDYRFRICTVSGHGRSPHVVFHGSAHLVPTARLVAGLEDVQVYDGEDAVFSLDLSTIIQGTWFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCPGVQDSAALTIQESPVHILSPQDRVSLTFTTSERVVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEGVSAFFGVTVQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAPVRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVAGDECAYFTVTITDVSSWIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPAARSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHEAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKLVSELTPLTVHEGDDATFRCEVSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRAGSTATSARLHVRETELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESHHDRTLARLSVRPRQLRVLRPLEDVTISEGGSATFQLELSQEGVTGEWARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSGCVSFTADSLRCAARLIVREVPVTIVRGPHDLEVTEGDTATFECELSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTYSCAVGTARAGPVRLTVRERTVAVLSELRSVSAREGDGATFECTVSEVETTGRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLALLEVEALPLQMCRHPPREKTVLVGRRAVLEVTVSRSGGHVCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQAGQDSTHTRLLVEGN", "length": 1896 }, "evidence": [ { "id": "E1BNH9", "url": "https://omabrowser.org/oma/group/E1BNH9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "pmid": "" }, { "name": "3M complex", "id": "GO:1990393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990393", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of dendrite morphogenesis", "id": "GO:0050775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050775", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "pmid": "" }, { "name": "protein localization to Golgi apparatus", "id": "GO:0034067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034067", "evidence": [ { "database": "UniProtKB", "id": "E1BNH9", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1163, "end_pos": 1165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1410, "end_pos": 1412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 517, "end_pos": 615, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH9" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 100, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 242, 544, 1135, 1400 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1163, "end_pos": 1165 }, { "start_pos": 1410, "end_pos": 1412 }, { "start_pos": 423, "end_pos": 425 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMF6-1", "uniprot_ac": "E1BMF6", "uniprot_id": "E1BMF6_BOVIN", "mass": { "chemical_mass": 101249.0, "monoisotopic_mass": 101249.0 }, "refseq": { "ac": "NP_001096570", "name": "N-alpha-acetyltransferase 16, NatA auxiliary subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096570" }, "gene_names": [ { "name": "NAA16", "type": "recommended", "evidence": [ { "id": "E1BMF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMF6" } ] }, { "name": "NAA16", "type": "synonym", "evidence": [ { "id": "NP_001096570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096570" } ] }, { "name": "NARG1L", "type": "synonym", "evidence": [ { "id": "NP_001096570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096570" } ] } ], "protein_names": [ { "name": "N-alpha-acetyltransferase 16, NatA auxiliary subunit", "type": "synonym", "evidence": [ { "id": "NP_001096570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096570" }, { "id": "E1BMF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMF6/entry#names_and_taxonomy" } ] }, { "name": "NMDA receptor regulated 1-like protein", "type": "synonym", "evidence": [ { "id": "NP_001096570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096570" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMF6", "url": "https://www.uniprot.org/uniprotkb/E1BMF6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NAA16", "url": "https://www.uniprot.org/uniprotkb/E1BMF6", "locus": { "chromosome": "12", "start_pos": 11542798, "end_pos": 11478920, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038251", "url": "https://www.ensembl.org/id/ENSBTAG00000038251" } ] } } ], "crossref": [ { "id": "E1BMF6", "url": "https://alphafold.ebi.ac.uk/entry/E1BMF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000038251", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038251", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538989", "url": "https://www.ncbi.nlm.nih.gov/gene/538989", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538989", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538989", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HTAINYD", "url": "https://omabrowser.org/oma/group/HTAINYD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22767:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22767:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001096570", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096570", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9Y4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MN02", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MN02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MN02-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MN02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NFQ2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NFQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMF6", "url": "https://www.uniprot.org/uniprotkb/E1BMF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMF6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNVQLPPKENNLFKRILKCYEQKQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKKEEAYEFVRKGLRNNVKSHVCWHVYGLLQRSDKRYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAVAHHLLKDYEMALKLLEEFRQTQQVPPSKIDYEYSELILYQNQVMREADLFQESLEHIETYEKQICDKLLVEEIKGEMLLKVGRLKEASEVFKNLIDRNAENWCYYEGLEKALQLSTLEERLQIYEDISKQHPRAISPRRLPLNLAPGEKFRELMDKFLRVNFSKGCPPLFTTLKSLYYNTEKISIIQELVTNYETSLKTCDFFSPYENGEKEPPTTLLWVQYFLAQHFDKLGQYSLALDYINAAIASTPTLIELFYMKAKIYKHMGNLREAVKWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSKFTREGTSAMENLNEMQCMWFQTECISAYQRLGRYGDALKKCHEVERHFSEITDDQFDFHTYCMRRMTLRAYVDLLRLEDILRRHGFYFKAARSAIEIYLKLYDNPLTSESKQQERNSENLSAKELKKMLSKQRRAEKKAKVEEVRKHVEREHQPKNQKKKRDEEEETSGFKEELLPEKLERIENPLEEAIKFLIPLKNLVADNIDTHLLAFEIYFRKGKFLLMLQSVKRAFAINRNNPWLHECLIKFSKSVSNHSNLPDIVSKVLSQEMQKIFVNKDLESFNEDFLTHNATSLQHLLSGAKMMYFLDKSRQEKAIAIATRLDEAIKDKNVKTLIKVSEALLDGSFGSCNSQYEEYRMACHRLLPFTSAFLPALSEVGSHGAARNHTANCDVLANET", "length": 863, "header": "tr|E1BMF6-1|E1BMF6_BOVIN Isoform 1 of N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Bos taurus OX=9913 GN=NAA16 PE=4 SV=3 CANONICAL=E1BMF6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M9Y4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMF6/entry#A0A3Q1M9Y4-1", "sequence": { "sequence": "MPNVQLPPKENNLFKRILKCYEQKQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKKEEAYEFVRKGLRNNVKSHVCWHVYGLLQRSDKRYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAVAHHLLKDYEMALKLLEEFRQTQQVPPSKIDYEYSELILYQNQVMREADLFQESLEHIETYEKQICDKLLVEEIKGEMLLKVGRLKEASEVFKNLIDRNAENWCYYEGLEKALQLSEKFRELMDKFLRVNFSKGCPPLFTTLKSLYYNTEKISIIQELVTNYETSLKTCDFFSPYENGEKEPPTTLLWVQYFLAQHFDKLGQYSLALDYINAAIASTPTLIELFYMKAKIYKHMGNLREAVKWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSKFTREGTSAMENLNEMQCMWFQTECISAYQRLGRYGDALKKCHEVERHFSEITDDQFDFHTYCMRRMTLRAYVDLLRLEDILRRHGFYFKAARSAIEIYLKLYDNPLTSESKQQERNSENLSAKELKKMLSKQRRAEKKAKVEEVRKHVEREHQPKNQKKKRDEEEETSGFKEELLPEKLERIENPLEEAIKFLIPLKNLVADNIDTHLLAFEIYFRKGKFLLMLQSVKRAFAINRNNPWLHECLIKFSKSVSNHSNLPDIVSKVLSQEMQKIFVNKDLESFNEDFLTHNATSLQHLLSGAKMMYFLDKSRQEKAIAIATRLDEAIKDKNVKTLIKVSEALLDGSFGSCNSQYEEYRMACHRLLPFTSAFLPALSEVGSHGAARNHTANCDVLANET", "length": 831, "header": "tr|A0A3Q1M9Y4-1|E1BMF6_BOVIN Computationally mapped isoform of N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Bos taurus OX=9913 GN=NAA16 PE=4 SV=1 CANONICAL=E1BMF6-1" }, "locus": { "chromosome": "12", "start_pos": 11540856, "end_pos": 11479199, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078828.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078828.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067011.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067011.1" } ] } }, { "isoform_ac": "A0A3Q1MN02-1", "url": "https://www.uniprot.org/uniprotkb/E1BMF6/entry#A0A3Q1MN02-1", "sequence": { "sequence": "MPNVQLPPKENNLFKRILKCYEQKQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKKEEAYEFVRKGLRNNVKSHVCWHVYGLLQRSDKRYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAVAHHLLKDYEMALKLLEEFRQTQQVPPSKIDYEYSELILYQNQVMREADLFQESLEHIETYEKQICDKLLVEEIKGEKFRELMDKFLRVNFSKGCPPLFTTLKSLYYNTEKISIIQELVTNYETSLKTCDFFSPYENGEKEPPTTLLWVQYFLAQHFDKLGQYSLALDYINAAIASTPTLIELFYMKAKIYKHMGNLREAVKWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSKFTREGTSAMENLNEMQCMWFQTECISAYQRLGRYGDALKKCHEVERHFSEITDDQFDFHTYCMRRMTLRAYVDLLRLEDILRRHGFYFKAARSAIEIYLKLYDNPLTSESKQQERNSENLSAKELKKMLSKQRRAEKKAKVEEVRKHVEREHQPKNQKKKRDEEEETSGFKEELLPEKLERIENPLEEAIKFLIPLKNLVADNIDTHLLAFEIYFRKGKFLLMLQSVKRAFAINRNNPWLHECLIKFSKSVSNHSNLPDIVSKVLSQEMQKIFVNKDLESFNEDFLTHNATSLQHLLSGAKMMYFLDKSRQEKAIAIATRLDEAIKDKNVKTLIKVSEALLDGSFGSCNSQYEEYRMACHRLLPFTSAFLPALSEVGSHGAARNHTANCDVLANET", "length": 791, "header": "tr|A0A3Q1MN02-1|E1BMF6_BOVIN Computationally mapped isoform of N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Bos taurus OX=9913 GN=NAA16 PE=4 SV=1 CANONICAL=E1BMF6-1" }, "locus": { "chromosome": "12", "start_pos": 11540856, "end_pos": 11479199, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068186.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068186.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073234.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073234.1" } ] } }, { "isoform_ac": "A0A3Q1NFQ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BMF6/entry#A0A3Q1NFQ2-1", "sequence": { "sequence": "MPNVQLPPKENNLFKRILKCYEQKQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKKEEAYEFVRKGLRNNVKSHVCWHVYGLLQRSDKRYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAVAHHLLKDYEMALKLLEEFRQTQQVPPSKIDYEYSELILYQNQVMREADLFQESLEHIETYEKQICDKLLVEEIKGTLEERLQIYEDISKQHPRAISPRRLPLNLAPGEKFRELMDKFLRVNFSKGCPPLFTTLKSLYYNTEKISIIQELVTNYETSLKTCDFFSPYENGEKEPPTTLLWVQYFLAQHFDKLGQYSLALDYINAAIASTPTLIELFYMKAKIYKHMGNLREAVKWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSKFTREGTSAMENLNEMQCMWFQTECISAYQRLGRYGDALKKCHEVERHFSEITDDQFDFHTYCMRRMTLRAYVDLLRLEDILRRHGFYFKAARSAIEIYLKLYDNPLTSESKQQERNSENLSAKELKKMLSKQRRAEKKAKVEEVRKHVEREHQPKNQKKKRDEEEETSGFKEELLPEKLERIENPLEEAIKFLIPLKNLVADNIDTHLLAFEIYFRKGKFLLMLQSVKRAFAINRNNPWLHECLIKFSKSVSNHSNLPDIVSKVLSQEMQKIFVNKDLESFNEDFLTHNATSLQHLLSGAKMMYFLDKSRQEKAIAIATRLDEAIKDKNVKTLIKVSEALLDGSFGSCNSQYEEYRMACHRLLPFTSAFLPALSEVGSHGAARNHTANCDVLANET", "length": 823, "header": "tr|A0A3Q1NFQ2-1|E1BMF6_BOVIN Computationally mapped isoform of N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Bos taurus OX=9913 GN=NAA16 PE=4 SV=1 CANONICAL=E1BMF6-1" }, "locus": { "chromosome": "12", "start_pos": 11540856, "end_pos": 11479199, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078071.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078071.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070512.1", "url": "https://www.ensembl.org/id/ENSBTAP00000070512.1" } ] } }, { "isoform_ac": "E1BMF6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMF6/entry#E1BMF6-1", "sequence": { "sequence": "MPNVQLPPKENNLFKRILKCYEQKQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKKEEAYEFVRKGLRNNVKSHVCWHVYGLLQRSDKRYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAVAHHLLKDYEMALKLLEEFRQTQQVPPSKIDYEYSELILYQNQVMREADLFQESLEHIETYEKQICDKLLVEEIKGEMLLKVGRLKEASEVFKNLIDRNAENWCYYEGLEKALQLSTLEERLQIYEDISKQHPRAISPRRLPLNLAPGEKFRELMDKFLRVNFSKGCPPLFTTLKSLYYNTEKISIIQELVTNYETSLKTCDFFSPYENGEKEPPTTLLWVQYFLAQHFDKLGQYSLALDYINAAIASTPTLIELFYMKAKIYKHMGNLREAVKWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSKFTREGTSAMENLNEMQCMWFQTECISAYQRLGRYGDALKKCHEVERHFSEITDDQFDFHTYCMRRMTLRAYVDLLRLEDILRRHGFYFKAARSAIEIYLKLYDNPLTSESKQQERNSENLSAKELKKMLSKQRRAEKKAKVEEVRKHVEREHQPKNQKKKRDEEEETSGFKEELLPEKLERIENPLEEAIKFLIPLKNLVADNIDTHLLAFEIYFRKGKFLLMLQSVKRAFAINRNNPWLHECLIKFSKSVSNHSNLPDIVSKVLSQEMQKIFVNKDLESFNEDFLTHNATSLQHLLSGAKMMYFLDKSRQEKAIAIATRLDEAIKDKNVKTLIKVSEALLDGSFGSCNSQYEEYRMACHRLLPFTSAFLPALSEVGSHGAARNHTANCDVLANET", "length": 863, "header": "tr|E1BMF6-1|E1BMF6_BOVIN Isoform 1 of N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Bos taurus OX=9913 GN=NAA16 PE=4 SV=3 CANONICAL=E1BMF6-1" }, "locus": { "chromosome": "12", "start_pos": 11540856, "end_pos": 11479199, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061596.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061596.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053222.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053222.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538989", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538989", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QE25-1", "protein_name": "N-alpha-acetyltransferase 15, NatA auxiliary subunit a", "gene_name": "naa15a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPSITLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNSKFAEHGETLAMKGLTLNCLGRKEEAYDLVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKIVEEFRKTQQTSPDKVDYEYSELLLYQNQLLREAELFKEALDHLTSYEKQICDKLAVEETRGELLLKLDRAGEATEVYHRLLERNPENWSYYQGLEKALKPKSAEDKQKIYEDAWVKYPKGLVPRRLPLSFLTGEKFRECLDRYLRMNFSKGCPPVFTTLKSLYHHKDKVAIIEELVVGYDKSLKTCKMFNQNDDGKIEPPTTLLWVQYFLAQHFNHIGKHTVALEYINTAIESTPTLIELFLIKAKIYKHAGNIREAARWMDEAQALDTADRFINSKCAKYLLKAGLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECALAYKSLNKYGEALKKCHEIERHFVEITDDQFDFHTYCMRKMTLRSYVDLLNLEDVLRMHPFYFKAARTAIEIYLSLHDNPLSDDNKESQADNANLTDKELKKLRNKQRRAQKKAQLEEEKKNAEKEKQLKNQKKKKEEDEEEIGGPKEELIPEKLAKIENPLEEAVKFLTPLKNLVKNKIETHLLAFEIYLRKEKYLLMLQSVKRAYSLDPDHPWLHQCLVRFFKGVSDSKDMPEAVQTVLKQEITKLFGESDPKTFNKNFLSKHANSIPHRVAAAKMMVFLDSSSEGKAAELATSLNESLTDRSLQTCAEVLQALRDGSLGSQQEKFTESYRVSCHGLYPYAVAFMPPGYQDNTAVTTNGDLSPCDHEDLPNEM", "length": 867 }, "evidence": [ { "id": "E1BMF6", "url": "https://omabrowser.org/oma/group/E1BMF6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0RC73-1", "protein_name": "N(alpha)-acetyltransferase 16, NatA auxiliary subunit", "gene_name": "Naa16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPCVQLPAKESALFKRVLKCYEQKQYKNGLKFCKMILSNPKFADHGETLAMKGLTLNCLGKREEAYEFVRKGLRSDVRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDTALKLLEEFRQTQQVPPNKIAYEYSELLLYQNQVMREANLFQESLEHIETYEKLICDKLLVEEIKGEMLLKLGRLKEASEVFKNLIDWNAENWCYYEGLEKALQLRSLDERLQIYEEISKQHPRAVSPRRLPLNFVPGKKFQELMDKFLRPNFSKGCPPLFTTLKSLYCNTEKVSIIQELVTNYEASLKMNGFFSPYENGEKEPPTTLIWVQYFLAQHFDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLREAAQWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSRFTREGTSAMENLNEMQCMWFETECISAYQRLGRYGDALKKCHEVERHFVEITDDQFDFHTYCMRRMTLRAYVDLLRLEDTLRRHTFYFKAARSAIEIYLKLHDNPLTSDSKQQDIDSENLSAKELKKMLSKQRRAQKKAKVEEERKHTERERQQKNQKKKREEEEEVTSGHKEELIPEKLERVDNPLEEAIKFLTPLKTLAADNIYTHLLAFEIYFRKGKFLLMLQSVKRAFAIDSNNPWLHECLIKFSKSVSNHSNLPDIVSTVLAQEMKKIFVDKDVHSFNEDFLKHNATSLQHLLAGAKMMYFLDKSRQEKAIATATRLDETIKNKNVKTLIKVSEALQDGSFGNCSSQYEEYRKTCHNLFPLTPAFLPAANEALGLSTELNHTAEHKLLTNEI", "length": 864 }, "evidence": [ { "id": "E1BMF6", "url": "https://omabrowser.org/oma/group/E1BMF6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6N069-1", "protein_name": "N-alpha-acetyltransferase 16, NatA auxiliary subunit", "gene_name": "NAA16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPNVLLPPKESNLFKRILKCYEQKQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQTQQVPPNKIDYEYSELILYQNQVMREADLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNLIDRNAENWCYYEGLEKALQISTLEERLQIYEEISKQHPKAITPRRLPLTLVPGERFRELMDKFLRVNFSKGCPPLFTTLKSLYYNTEKVSIIQELVTNYEASLKTCDFFSPYENGEKEPPTTLLWVQYFLAQHFDKLGQYSLALDYINAAIASTPTLIELFYMKAKIYKHIGNLKEAAKWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSKFTREGTSAMENLNEMQCMWFQTECISAYQRLGRYGDALKKCHEVERHFFEITDDQFDFHTYCMRKMTLRAYVDLLRLEDILRRHAFYFKAARSAIEIYLKLYDNPLTNESKQQEINSENLSAKELKKMLSKQRRAQKKAKLEEERKHAERERQQKNQKKKRDEEEEEASGLKEELIPEKLERVENPLEEAVKFLIPLKNLVADNIDTHLLAFEIYFRKGKFLLMLQSVKRAFAINSNNPWLHECLIRFSKSVSNHSNLPDIVSKVLSQEMQKIFVKKDLESFNEDFLKRNATSLQHLLSGAKMMYFLDKSRQEKAIAIATRLDETIKDKDVKTLIKVSEALLDGSFGNCSSQYEEYRMACHNLLPFTSAFLPAVNEVDNPNVALNHTANYDVLANEI", "length": 864 }, "evidence": [ { "id": "E1BMF6", "url": "https://omabrowser.org/oma/group/E1BMF6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBB4-1", "protein_name": "N-alpha-acetyltransferase 16, NatA auxiliary subunit", "gene_name": "Naa16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPCVQLPAKESALFKRVLKCYEQKQYKNGLKFCKMILSNPKFAEHGETLAMKGLILNCLGKREEAYEFVRKGLRSDVRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDTALKLLEEFRQTQQVPPNKIAYEYSELLLYQNQVMREANLFQESLEHIETYEKLICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDWNAENWCYYEGLEKALQLRSLDERLQLYEEVSKQHPRAVSPRRLPLSFAPGKKFRELMDKFLRPNFSKGCPPLFTTLKSLYCDTEKVSIIQELVTNYEASLKMNGYFSPYENGEKEPPTTLIWVQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSRFTREGTSAMENLNEMQCMWFETECISAYQRLGRYGDALKKCHEVERHFLEITDDQFDFHTYCMRKMTLRAYVGLLRLEDALRRHTFYFKAARSAIEIYLKLHDNPLTNDSKQQDIDSENLSAKEMKKMLSKQRRAQKKAKVEEERKHTERERQQKNQKKKREEEEEVTSGHKEELIPEKLERVDNPLEEAIKFLTPLKTLAAESIDTHLLAFEIYFRKGKFLLMLQSVKRAFAIESNNPWLHECLIKFSKSVSNHSNLPDIVSKVLAQEMKKIFVNKDLHSFNEDFLRHNATSLQHLLAGAKMMYFLDKSRQEKAIATATRLDETIKNKNVKTLIKVSEALLDGSFGNCSSQYEEYRKTCHSLLPLTPAFLPAAREALGLSAELNHTADHKLLMNEI", "length": 864 }, "evidence": [ { "id": "E1BMF6", "url": "https://omabrowser.org/oma/group/E1BMF6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BMF6", "url": "https://www.uniprot.org/uniprotkb/E1BMF6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BMF6", "url": "https://www.uniprot.org/uniprotkb/E1BMF6" } ], "pmid": "" }, { "name": "NatA complex", "id": "GO:0031415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031415", "evidence": [ { "database": "UniProtKB", "id": "E1BMF6", "url": "https://www.uniprot.org/uniprotkb/E1BMF6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "E1BMF6", "url": "https://www.uniprot.org/uniprotkb/E1BMF6" } ], "pmid": "" }, { "name": "acetyltransferase activator activity", "id": "GO:0010698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010698", "evidence": [ { "database": "UniProtKB", "id": "E1BMF6", "url": "https://www.uniprot.org/uniprotkb/E1BMF6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "E1BMF6", "url": "https://www.uniprot.org/uniprotkb/E1BMF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" }, { "start_pos": 756, "end_pos": 758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 851, "end_pos": 853, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMF6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 863, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMF6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMF6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 317, "end_pos": 319 }, { "start_pos": 586, "end_pos": 588 }, { "start_pos": 720, "end_pos": 722 }, { "start_pos": 756, "end_pos": 758 }, { "start_pos": 851, "end_pos": 853 }, { "start_pos": 861, "end_pos": 863 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNJ2-1", "uniprot_ac": "E1BNJ2", "uniprot_id": "E1BNJ2_BOVIN", "mass": { "chemical_mass": 37453.0, "monoisotopic_mass": 37453.0 }, "refseq": { "ac": "NP_001193024", "name": "bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193024" }, "gene_names": [ { "name": "MTHFD2L", "type": "recommended", "evidence": [ { "id": "E1BNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ] }, { "name": "MTHFD2L", "type": "synonym", "evidence": [ { "id": "NP_001193024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193024" } ] } ], "protein_names": [ { "name": "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like", "type": "synonym", "evidence": [ { "id": "E1BNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2/entry#names_and_taxonomy" } ] }, { "name": "bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001193024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193024" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNJ2", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MTHFD2L", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2", "locus": { "chromosome": "6", "start_pos": 89239036, "end_pos": 89093080, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000043960", "url": "https://www.ensembl.org/id/ENSBTAG00000043960" } ] } } ], "crossref": [ { "id": "E1BNJ2", "url": "https://alphafold.ebi.ac.uk/entry/E1BNJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000043960", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000043960", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01080", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01080", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "536269", "url": "https://www.ncbi.nlm.nih.gov/gene/536269", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536269", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536269", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YGCMKML", "url": "https://omabrowser.org/oma/group/YGCMKML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MCL5", "url": "https://www.orthodb.org/?gene=A0A3Q1MCL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N3G9", "url": "https://www.orthodb.org/?gene=A0A3Q1N3G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BNJ2", "url": "https://www.orthodb.org/?gene=E1BNJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48099:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48099:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02882", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02882", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-196757", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196757", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193024", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193024", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "22892", "url": "https://www.rhea-db.org/rhea/22892", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "23700", "url": "https://www.rhea-db.org/rhea/23700", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MCL5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N3G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNJ2", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNJ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVVARGFWLLRGRLGRVSALSRIAESPFAAPGAAGQAFRGFRSSGMRYDAIIISGTEMAKQIQKEIQHGVDSWVSLGNRRPHLSIILVGDNPASHTYVRRKIKAAAAVGICSEIILKPKDVSQEELLDITDQLNADPRVSGILVQLPLPDHMDERTVCNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIRRTGIETFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTLLADVIIVAAGIPKLITSDMVKEGAAVIDVGINYVYDPITGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKKIIY", "length": 347, "header": "tr|E1BNJ2-1|E1BNJ2_BOVIN Isoform 1 of Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like OS=Bos taurus OX=9913 GN=MTHFD2L PE=3 SV=2 CANONICAL=E1BNJ2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MCL5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2/entry#A0A3Q1MCL5-1", "sequence": { "sequence": "MTVVARGFWLLRGRLGRVSALSRIAESPFAAPGAAGQAFRGFRSSGMRTSREKRFHLPEVATVCLPTCPHPRYDAIIISGTEMAKQIQKEIQHGVDSWVSLGNRRPHLSIILVGDNPASHTYVRRKIKAAAAVGICSEIILKPKDVSQEELLDITDQLNADPRVSGILVQLPLPDHMDERTVCNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIRRTGIETFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTLLADVIIVAAGIPKLITSDMVKEGAAVIDVGINYVYDPITGKTKLVGDVDFEGPENFAKRLHWS", "length": 346, "header": "tr|A0A3Q1MCL5-1|E1BNJ2_BOVIN Computationally mapped isoform of Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like OS=Bos taurus OX=9913 GN=MTHFD2L PE=3 SV=2 CANONICAL=E1BNJ2-1" }, "locus": { "chromosome": "6", "start_pos": 89222667, "end_pos": 89093219, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068660.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068660.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068587.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068587.2" } ] } }, { "isoform_ac": "A0A3Q1N3G9-1", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2/entry#A0A3Q1N3G9-1", "sequence": { "sequence": "MTVVARGFWLLRGRLGRVSALSRIAESPFAAPGAAGQAFRGFRSSGMRTSREKRFHLPEVATVCLPTCPHPRYDAIIISGTEMAKQIQKEIQHGVDSWVSLGNRRPHLSIILVGDNPASHTYVRRKIKAAAAVGICSEIILKPKDVSQEELLDITDQLNADPRVSGILVQLPLPDHMDERTVCNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIRRTGIETFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTLLADVIIVAAGIPKLITSDMVKEGAAVIDVGINYVYDPITGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKKIIY", "length": 371, "header": "tr|A0A3Q1N3G9-1|E1BNJ2_BOVIN Computationally mapped isoform of Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like OS=Bos taurus OX=9913 GN=MTHFD2L PE=3 SV=3 CANONICAL=E1BNJ2-1" }, "locus": { "chromosome": "6", "start_pos": 89238076, "end_pos": 89093219, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076114.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076114.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064057.3", "url": "https://www.ensembl.org/id/ENSBTAP00000064057.3" } ] } }, { "isoform_ac": "E1BNJ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2/entry#E1BNJ2-1", "sequence": { "sequence": "MTVVARGFWLLRGRLGRVSALSRIAESPFAAPGAAGQAFRGFRSSGMRYDAIIISGTEMAKQIQKEIQHGVDSWVSLGNRRPHLSIILVGDNPASHTYVRRKIKAAAAVGICSEIILKPKDVSQEELLDITDQLNADPRVSGILVQLPLPDHMDERTVCNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIRRTGIETFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTLLADVIIVAAGIPKLITSDMVKEGAAVIDVGINYVYDPITGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKKIIY", "length": 347, "header": "tr|E1BNJ2-1|E1BNJ2_BOVIN Isoform 1 of Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like OS=Bos taurus OX=9913 GN=MTHFD2L PE=3 SV=2 CANONICAL=E1BNJ2-1" }, "locus": { "chromosome": "6", "start_pos": 89238076, "end_pos": 89093219, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061329.3", "url": "https://www.ensembl.org/id/ENSBTAT00000061329.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053516.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053516.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:536269", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536269", "resource": "KEGG Pathway" }, { "id": "R-BTA-196757", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196757", "resource": "Reactome", "description": "Metabolism of folate and pterines" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XDB2-1", "protein_name": "methenyltetrahydrofolate cyclohydrolase", "gene_name": "MTHFD2L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAAFCSPCSALRSGLAPLCRWRALPRPASRRAGSVPRSAASDEAAVISGTKLAKQVLKEVQRDVESWISCGNKRPHLTVILVGDNPASHIYVRNKVKAAAAVGISSEVILRPKYISQEELLDMTLKLNKDSAVSGVLVQLPLPDHIDERTVCNAIAPEKDVDGFHIINVGRLCLDQPSVIPATAAAVWEIIKRTGIQTFGKNILVAGRSKNVGMPISMLLHTDGEHERPGGDATVTIAHRHTPKEQLKIHTQLADIVIVAAGIPKLITTDMVKEGAAVIDVGINHIHDPLTGKTKLVGDVDFEEVKKKAGFITPVPGGVGPMTVAMLLKNTLIVAKKLIY", "length": 342 }, "evidence": [ { "id": "E1BNJ2", "url": "https://omabrowser.org/oma/group/E1BNJ2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3YZG8-1", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "gene_name": "Mthfd2l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATRARGFSLLRGRLGRGPVRAPGVAERAWRGFGSSGRRHEAVIISGTNMAKQIQKEIQQGVESWIALGNRRPHLSIILVGDNPASHTYVRNKIKAASAVGICSELIIKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRAGIETFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPREQLKAHTQLADIIIVAAGIPRLITADMVREGAAVIDVGINYIQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKNIAY", "length": 338 }, "evidence": [ { "id": "E1BNJ2", "url": "https://omabrowser.org/oma/group/E1BNJ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZUA0-1", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "gene_name": "Mthfd2l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATRARGLSLLRGRLGRGPARAPGVAERAWRGFGSSSRRHEAVIISGTEMAKQIRRELQQGVESWLALGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELIVKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRAGIETFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRHTPREQLKAHTQLAEIIIVAAGIPGLITADMVREGATVIDVGINYVQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKNITY", "length": 338 }, "evidence": [ { "id": "E1BNJ2", "url": "https://omabrowser.org/oma/group/E1BNJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O65271-1", "protein_name": "Bifunctional protein FolD 4, chloroplastic", "gene_name": "FOLD4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASMMFTDCSSTTTSRLIHLNRSSGTFLLRQCVGQLRLQTTASGRGCCIRSSSSPISSISADTKSEGGAIVIDGKAVAKKIRDEITIEVSRMKESIGVIPGLAVILVGDRKDSATYVRNKKKACDSVGIKSFEVRLAEDSSEEEVLKSVSGFNDDPSVHGILVQLPLPSHMDEQNILNAVSIEKDVDGFHPLNIGRLAMRGREPLFVPCTPKGCIELLHRYNIEIKGKRAVVIGRSNIVGMPAALLLQREDATVSIIHSRTKNPEEITREADIIISAVGQPNMVRGSWIKPGAVLIDVGINPVEDPSAARGYRLVGDICYEEASKVASAITPVPGGVGPMTIAMLLSNTLTSAKRIHNFQ", "length": 360 }, "evidence": [ { "id": "E1BNJ2", "url": "https://omabrowser.org/oma/group/E1BNJ2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9H903-4", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "gene_name": "MTHFD2L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVPVRGFSLLRGRLGRAPALGRSTAPSVRAPGEPGSAFRGFRSSGVRHEAIIISGTEMAKHIQKEIQRGVESWVSLGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRTGIQTFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAVIDVGINYVHDPVTGKTKLVGDVDFEAVKKKAGFITPVPGGVGPMTVAMLLKNTLLAAKKIIY", "length": 347 }, "evidence": [ { "id": "E1BNJ2", "url": "https://omabrowser.org/oma/group/E1BNJ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "one-carbon metabolic process", "id": "GO:0006730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006730", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ2", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ], "pmid": "" }, { "name": "folic acid-containing compound metabolic process", "id": "GO:0006760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006760", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ2", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ], "pmid": "" }, { "name": "tetrahydrofolate interconversion", "id": "GO:0035999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035999", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ2", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ], "pmid": "" }, { "name": "carboxylic acid metabolic process", "id": "GO:0019752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019752", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ2", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "methenyltetrahydrofolate cyclohydrolase activity", "id": "GO:0004477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004477", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ2", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ], "pmid": "" }, { "name": "methylenetetrahydrofolate dehydrogenase (NADP+) activity", "id": "GO:0004488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004488", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ2", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ], "pmid": "" }, { "name": "methylenetetrahydrofolate dehydrogenase (NAD+) activity", "id": "GO:0004487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004487", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ2", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ2", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ2", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22892", "name": "", "equation": "(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methenyltetrahydrofolate + NADH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P5C2-1", "A0AAA9SQ90-1", "E1BNJ2-1" ], "evidence": [ { "id": "22892", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22892" } ] }, { "id": "23700", "name": "", "equation": "(6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SQ90-1", "E1BNJ2-1", "Q0P5C2-1" ], "evidence": [ { "id": "23700", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23700" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9SQ90", "gene_name": "MTHFD2", "activity": [ { "ec_number": "3.5.4.9", "activity": "(6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+).", "evidence": [ { "id": "A0AAA9SQ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ90" } ] }, { "ec_number": "3.5.4.9", "activity": "", "evidence": [ { "id": "A0AAA9SQ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ90" } ] } ] }, { "uniprot_ac": "E1BNJ2", "gene_name": "MTHFD2L", "activity": [ { "ec_number": "3.5.4.9", "activity": "(6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+).", "evidence": [ { "id": "E1BNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ] }, { "ec_number": "3.5.4.9", "activity": "", "evidence": [ { "id": "E1BNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" } ] } ] }, { "uniprot_ac": "Q0P5C2", "gene_name": "MTHFD2", "activity": [ { "ec_number": "3.5.4.9", "activity": "(6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+).", "evidence": [ { "id": "Q0P5C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5C2" } ] }, { "ec_number": "1.5.1.15", "activity": "(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methenyltetrahydrofolate + NADH.", "evidence": [ { "id": "Q0P5C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5C2" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNJ2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 347, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNJ2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNJ2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" }, { "id": "PF02882", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02882" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 344, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ2" }, { "id": "PF00763", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00763" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 169, "start_aa": "Ile", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.4.9", "ec_name": "(6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+).", "evidence": [ { "id": "3.5.4.9", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.9" }, { "id": "3.5.4.9", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.4.9" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"MDQEGGGDGQKAPSFQWRNYKLIVDPALDPALRRPSQKVYRYDGIHFSVNDSKYIPVEDLQDPRCHVRSKNRDFSLPVPKFKLDEFYIGQIPLKEVTFARLNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSVMGNIIHAQLDIKGQQRMKYYELIVNGSYTPQTVPTGGKALSEKFQGSGAATETTDSRRRSSSDTAAFPAGSAVVGTPGNGTPCSQDTSFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDSFSRRHFSASSAPTTTSAAICATTAATASASSSSSLSSSSSSSSSSSSSHFRGSDSNYPAYYESWNRYQRHASYPPRRATRDEPPGASFAENTAERFTPSYTSYLPPEPNRPADQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEARTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSTGPGARDTGSEAPSGSGHGPCTPPPAPASFEDVAPTGSGEPGATRESPKANGQNQASPCSSGEDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPPHIYDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLTAASAGPPGGAFGEAFLPFPPHQEAAYGLPYALYAQGQEGRGAYSREAYHLPLPMAAEPLPSSVSGEEARLPPREEAELAEGKALPSAGTVGRVLATLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAKQQAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDAEREKEVGEPGRPGTKPPKRDEERSKTQGKHRKSFALDSEGEEASQESSSEKDEEDEEEDEEDEEREEAMDAAKKETEASDGEDGESDSSSKCSLYADSDGENDSTSDSESSGSSSSSSSSSSSSSSSSSSSSSESSSEEEEEEEQPAIILAALSPPRDVPTPLSAPAEEPEPERVEDSPVTPLPEQEKSPVRPAGSTEEPPSSAPQPPPEPPAGPLAPTPRPDDRPSSPIPLLPPPKKRRKTVSFSAVEEAPAPEPPPAALPQAKSSGPASRKAPRAVERTIRNLPLDHASLVKSWPEEVSRGGRNRAGGRGRSAEEEEAEPATEVDLAVLADLALTPARRGLPALPAADDSEAAETPDEAERPGPLLSHILLEHNYALAVRPPLPPPPPPSTPAPRPLEPVPAPAALFSSPADEVLEAPEVVVAEVEEPKQPPQQQEDGEEEEEEEEESESSESSSSSSSDGEGATRRRSLRSHTRRRRPPPPPPPPPPPTFDPRSEFEQMTILYDIWNSGLDLEDMSYLRLTYERLLQQTSGADWLNDTHWVQHTITNLSTPKRKRRPQDGPREHQTGSARSEGYYPISKKEKDRYLDVCPVSARQLEGVDTQGTNRVLSERRSEQRRLLSAIGTSAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFPLEDNKIPCLCGTESCRGSLN", "length": 1708, "header": "tr|E1BLX2-1|E1BLX2_BOVIN Isoform 1 of [histone H3]-lysine(4) N-methyltransferase OS=Bos taurus OX=9913 GN=SETD1A PE=4 SV=3 CANONICAL=E1BLX2-1" }, "locus": { "chromosome": "25", "start_pos": 27118095, "end_pos": 27096284, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003027.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003027.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003027.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003027.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1316, "start_aa": "Thr", "end_pos": 1316, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1316", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 598, "start_aa": "Thr", "end_pos": 598, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr598", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 914, "start_aa": "Thr", "end_pos": 914, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr914", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:782887", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782887", "resource": "KEGG Pathway" }, { "id": "R-BTA-3214841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214841", "resource": "Reactome", "description": "PKMTs methylate histone lysines" }, { "id": "R-BTA-8936459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8936459", "resource": "Reactome", "description": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" }, { "id": "R-BTA-9772755", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9772755", "resource": "Reactome", "description": "Formation of WDR5-containing histone-modifying complexes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K6T6-1", "protein_name": "[histone H3]-lysine(4) N-methyltransferase", "gene_name": "Setd1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQEGGGDGQKAPSFQWRNYKLIVDPALDPALRRPSQKVYRYDGVHFSVSDSKYTPVEDLQDPRCHVRSKTRDFSLPVPKFKLDEFYIGQVPLKEVTFARLNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSVMGNIIHAQLDIKGQQRMKYYELIVNGSYTPQTVPTGGKALSEKFQGSSGATTETTEARRRSSSDTAAYSAGTTVGGTPGNGTPCSQDTNFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDSFSRRHFSASSAPATTATATSATAAATVASSSSSSSSSSSSSSSSSSSSASQFRGSDSSYPAYYESWNRYQRHTSYPPRRATREDPSGAPFAENTAERFPPSYTSYLAPEPNRSTDQDYRPPASEAPPPEPPEPGGGSGGGGGGGSGGGGGAPSPEREEARTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSAGPGARDAGGEVPSGAGHGPCTPPPAPANFEDVAPTGSGEPGAARESPKANGQNQASPCSSGEDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPHPDGPPPPEYPPPPPPPPHIYDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLTAASAGPPGGAFGEAFLPFPPPQEAAYGLPYALYTQGQEGRGAYSREAYHLPLPMAAEPLPSSSVSGEEARLPHREEAEIAESKALPSAGTVGRVLATLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAKQQAKEEDKEKMKLKEPGMLSLVDWAKSGGITGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEREKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEDDDEEDEEDEEREEAVDATKKEAEASDGEDEDGDSSSQCSLYADSDGEDGSTSDSESGSSSSSPSSSSSSSSSSSSESSSEEEEQSAVIPSASPPPREVPEPLPAPDEKPETDRVVDSPVMPLPEKETTSTQPAGPAEEPPPNIPQPPPEPPAGPPDPPPRLDERPSSPIPLLPPPKKRRKTVSFSATEEAPVPEPSTASPLQAKSPGPVSRKVPRVVERTIRNLPLDHASLVKSWPEEVARGGRNRAGGRVRSTEEEEATESGTEVDLAVLADLALTPARRGLAAIPTGDDSEATETSDEAERPSPLLSHILLEHNYALAIKPPPTTPAPRPLEPAPALAALFSSPADEVLEAPEVVVAEAEEPKQPLQQQQHPEQEGEDEEEDEEEESESSESSSSSSSSDEEGAIRRRSLRSHTRRRRPPLPPPPPPPPSFEPRSEFEQMTILYDIWNSGLDLEDMSYLRLTYERLLQQTSGADWLNDTHWVHHTITNLSTPKRKRRPQDGPREHQTGSARSEGYYPISKKEKDKYLDVCPVSARQPEGVDTQGTNRVLSERRSEQRRLLSAIGTSAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFPLEDNKIPCLCGTESCRGSLN", "length": 1717 }, "evidence": [ { "id": "E1BLX2", "url": "https://omabrowser.org/oma/group/E1BLX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PYH6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQEGGGDGQKAPSFQWRNYKLIVDPALDPALRRPSQKVYRYDGVHFSVSDSKYTPVEDLQDPRCHVRSKARDFSLPVPKFKLDEFYIGQIPLKEVTFARLNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSVMGNIIHAQLDIKGQQRMKYYELIVNGSYTPQTVPTGGKALSEKFQGSGAAAETTEARRRSSSDTAAYPAGTTVGGTPGNGTPCSQDTNFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDSFSRRHFSTSSAPATTATATSATAAATAASSSSSSSSSSSSSSSSSSSASQFRGSDSSYPAYYESWNRYQRHTSYPPRRATREDPSGASFAENTAERFPPSYTSYLAPEPNRSTDQDYRPPASEAPPPEPPEPGGGGGGSGGGGGGGGGGGGGAPSPEREEARTPPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSAGPGARDAGAEVPSGAGHGPCTPPPAPANFEDVAPTGSGEPGAARESPKANGQNQASPCSSGEDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPPPHIYDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLTAASAGPPGGAFGEAFLPFPPPQEAAYGLPYALYTQGQEGRGSYSREAYHLPLPMAAEPLPSSSVSGEEARLPHREEAEIAESKVLPSAGTVGRVLATLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAKQQAKEEDKEKMKLKEPGMLSLVDWAKSGGITGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEREKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFTLDSEGEEASQESSSEKDEDDDDEDEEDEEQEEAVDATKKEAEASDGEDEDSDSSSQCSLYADSDGENGSTSDSESGSSSSSSSSSSSSSSSSSSESSSEEEEQSAVIPSASPPREVPEPLPAPDEKPETDGLVDSPVMPLSEKETLPTQPAGPAEEPPPSVPQPPAEPPAGPPDAAPRLDERPSSPIPLLPPPKKRRKTVSFSAAEEAPVPEPSTAAPLQAKSSGPVSRKVPRVVERTIRNLPLDHASLVKSWPEEVARGGRNRAGGRVRSTEEEEATESGTEVDLAVLADLALTPARRGLATLPTGDDSEATETSDEAERPSPLLSHILLEHNYALAIKPPPTTPAPRPLEPAPALAALFSSPADEVLEAPEVVVAEAEEPKQQLQQQHPEQEGEEEEEDEEEESESSESSSSSSSDEEGAIRRRSLRSHTRRRRPPLPPPPPPPPSFEPRSEFEQMTILYDIWNSGLDLEDMSYLRLTYERLLQQTSGADWLNDTHWVQHTITNLSTPKRKRRPQDGPREHQTGSARSEGYYPISKKEKDKYLDVCPVSARQLEGGDTQGTNRVLSERRSEQRRLLSAIGTSAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFPLEDNKIPCLCGTESCRGSLN", "length": 1716 }, "evidence": [ { "id": "E1BLX2", "url": "https://omabrowser.org/oma/group/E1BLX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQEGGGDGQKAPSFQWRNYKLIVDPALDPALRRPSQKVYRYDGVHFSVNDSKYIPVEDLQDPRCHVRSKNRDFSLPVPKFKLDEFYIGQIPLKEVTFARLNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSVMGNIIHAQLDIKGQQRMKYYELIVNGSYTPQTVPTGGKALSEKFQGSGAATETAESRRRSSSDTAAYPAGTTAVGTPGNGTPCSQDTSFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPPHIYDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLIAASAGPPGGAFGEAFLPFPPPQEAAYGLPYALYAQGQEGRGAYSREAYHLPMPMAAEPLPSSSVSGEEARLPPREEAELAEGKTLPTAGTVGRVLAMLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAKQQAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAVLADLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHILLEHNYALAVKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPPPRAYEPRSEFEQMTILYDIWNSGLDSEDMSYLRLTYERLLQQTSGADWLNDTHWVHHTITNLTTPKRKRRPQDGPREHQTGSARSEGYYPISKKEKDKYLDVCPVSARQLEGVDTQGTNRVLSERRSEQRRLLSAIGTSAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFPLEDNKIPCLCGTESCRGSLN", "length": 1707 }, "evidence": [ { "id": "E1BLX2", "url": "https://omabrowser.org/oma/group/E1BLX2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "histone H3K4 monomethyltransferase activity", "id": "GO:0140945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140945", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "regulation of hematopoietic stem cell differentiation", "id": "GO:1902036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902036", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" }, { "name": "regulation of chromatin organization", "id": "GO:1902275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902275", "evidence": [ { "database": "UniProtKB", "id": "E1BLX2", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1462, "end_pos": 1464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1473, "end_pos": 1475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60264", "name": "", "equation": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TQW6-1", "E1B9N8-1", "F1MHA1-1", "E1BKN0-1", "E1B906-1", "F1N6Y5-1", "E1BLX2-1", "A0ABI0NZS0-1" ], "evidence": [ { "id": "60264", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60264" } ] }, { "id": "60268", "name": "", "equation": "N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MHA1-1", "E1B906-1", "E1BKN0-1", "F1N6Y5-1", "E1BLX2-1" ], "evidence": [ { "id": "60268", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60268" } ] }, { "id": "60272", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N6Y5-1", "E1BLX2-1" ], "evidence": [ { "id": "60272", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60272" } ] }, { "id": "R-BTA-5159245", "name": "SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1MF12-1", "E1BKN0-1", "F1N6Y5-1", "A0AAA9TQW6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-5159245", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5159245" } ] }, { "id": "R-BTA-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKN0-1", "F1N6Y5-1", "G3X834-1", "A0AAA9TQW6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-5244692", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5244692" } ] }, { "id": "R-BTA-5637686", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1MF12-1", "E1BKN0-1", "F1N6Y5-1", "A0AAA9TQW6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-5637686", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5637686" } ] }, { "id": "R-BTA-8936481", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKN0-1", "A0ABZ3NNC5-1", "F1N6Y5-1", "A0AAA9TQW6-1", "A0A3Q1MLT2-1", "E1B8D6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-8936481", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8936481" } ] }, { "id": "R-BTA-8936621", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKN0-1", "A0ABZ3NNC5-1", "F1N6Y5-1", "A0AAA9TQW6-1", "A0A3Q1MLT2-1", "E1B8D6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-8936621", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8936621" } ] }, { "id": "R-BTA-8937016", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKN0-1", "A0ABZ3NNC5-1", "F1N6Y5-1", "A0AAA9TQW6-1", "A0A3Q1MLT2-1", "E1B8D6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-8937016", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8937016" } ] }, { "id": "R-BTA-8937050", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKN0-1", "A0ABZ3NNC5-1", "F1N6Y5-1", "A0AAA9TQW6-1", "A0A3Q1MLT2-1", "E1B8D6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-8937050", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8937050" } ] }, { "id": "R-BTA-9676257", "name": "Formation of the SET1A complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-9676257", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9676257" } ] }, { "id": "R-BTA-9821475", "name": "CXXC1 and WDR82 bind SET1A complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-9821475", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9821475" } ] }, { "id": "R-BTA-9821486", "name": "HCFC1 binds SET1A complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-9821486", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9821486" } ] }, { "id": "R-BTA-9821931", "name": "BOD1L1 binds SET1A complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-9821931", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9821931" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MF12", "gene_name": "SETD3", "activity": [ { "ec_number": "2.1.1.85", "activity": "L-histidyl-[protein] + S-adenosyl-L-methionine = N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1MF12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF12" } ] }, { "ec_number": "2.1.1.85", "activity": "", "evidence": [ { "id": "A0A3Q1MF12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF12" } ] } ] }, { "uniprot_ac": "A0A3Q1MLT2", "gene_name": "KAT2B", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A3Q1MLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLT2" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A3Q1MLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLT2" } ] } ] }, { "uniprot_ac": "A0AAA9TQW6", "gene_name": "KMT2C", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0AAA9TQW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQW6" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0AAA9TQW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQW6" } ] } ] }, { "uniprot_ac": "A0ABI0NZS0", "gene_name": "SETD7", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0ABI0NZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0ABI0NZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ] } ] }, { "uniprot_ac": "A0ABZ3NNC5", "gene_name": "PRMT1", "activity": [ { "ec_number": "2.1.1.319", "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "A0ABZ3NNC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5" } ] }, { "ec_number": "2.1.1.319", "activity": "", "evidence": [ { "id": "A0ABZ3NNC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNC5" } ] } ] }, { "uniprot_ac": "E1B8D6", "gene_name": "EP300", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "E1B8D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8D6" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "E1B8D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8D6" } ] } ] }, { "uniprot_ac": "E1B906", "gene_name": "SETD4", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1B906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1B906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ] } ] }, { "uniprot_ac": "E1B9N8", "gene_name": "KMT2D", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1B9N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N8" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1B9N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N8" } ] } ] }, { "uniprot_ac": "E1BKN0", "gene_name": "KMT2B", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1BKN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKN0" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1BKN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKN0" } ] } ] }, { "uniprot_ac": "E1BLX2", "gene_name": "SETD1A", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1BLX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1BLX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ] } ] }, { "uniprot_ac": "F1MHA1", "gene_name": "KMT2A", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "F1MHA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHA1" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "F1MHA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHA1" } ] } ] }, { "uniprot_ac": "F1N6Y5", "gene_name": "SETD1B", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "F1N6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6Y5" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "F1N6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6Y5" } ] } ] }, { "uniprot_ac": "G3X834", "gene_name": "", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.364", "ec_name": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "2.1.1.364", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364" }, { "id": "2.1.1.364", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.364" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 598, 914, 1316 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1025, "end_pos": 1027 }, { "start_pos": 1462, "end_pos": 1464 }, { "start_pos": 1473, "end_pos": 1475 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 476, "end_pos": 478 }, { "start_pos": 50, "end_pos": 52 }, { "start_pos": 515, "end_pos": 517 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BN06-1", "uniprot_ac": "E1BN06", "uniprot_id": "E1BN06_BOVIN", "mass": { "chemical_mass": 47665.0, "monoisotopic_mass": 47665.0 }, "refseq": { "ac": "NP_001107232", "name": "ras association domain-containing protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107232" }, "gene_names": [ { "name": "RASSF5", "type": "recommended", "evidence": [ { "id": "E1BN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN06" } ] }, { "name": "RASSF5", "type": "synonym", "evidence": [ { "id": "NP_001107232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107232" } ] } ], "protein_names": [ { "name": "Ras association domain-containing protein 5", "type": "recommended", "evidence": [ { "id": "E1BN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN06/entry#names_and_taxonomy" } ] }, { "name": "New ras effector 1", "type": "synonym", "evidence": [ { "id": "E1BN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN06/entry#names_and_taxonomy" } ] }, { "name": "Ras association (RalGDS/AF-6) domain family 5", "type": "synonym", "evidence": [ { "id": "NP_001107232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107232" } ] }, { "name": "ras association domain-containing protein 5", "type": "synonym", "evidence": [ { "id": "NP_001107232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107232" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN06", "url": "https://www.uniprot.org/uniprotkb/E1BN06" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RASSF5", "url": "https://www.uniprot.org/uniprotkb/E1BN06", "locus": { "chromosome": "16", "start_pos": 4367194, "end_pos": 4293683, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010427", "url": "https://www.ensembl.org/id/ENSBTAG00000010427" } ] } } ], "crossref": [ { "id": "E1BN06", "url": "https://alphafold.ebi.ac.uk/entry/E1BN06", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010427", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010427", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17220", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17220", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20886", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20886", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21892", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21892", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539767", "url": "https://www.ncbi.nlm.nih.gov/gene/539767", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539767", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539767", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VDCKFTC", "url": "https://omabrowser.org/oma/group/VDCKFTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MXG2", "url": "https://www.orthodb.org/?gene=A0A3Q1MXG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BN06", "url": "https://www.orthodb.org/?gene=E1BN06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001107232", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107232", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MXG2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MXG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6R7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6R7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3N8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3N8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3N8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS28", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS28-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN06", "url": "https://www.uniprot.org/uniprotkb/E1BN06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN06-1", "url": "https://www.uniprot.org/uniprotkb/E1BN06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMASPAIGQRPYRLLLEPEPPHYLQSLSDPEPLPPPPPPPPPGHSSRRCAPAPLSTAPGAHERRSAWRAARGDPEPQPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFVELALRGGRGWCDLCGREVWWRALSCANCKFTCHPECRSLIQLDCTQQDGANRDRPSPESTLAVTFSQNDCKPPEEPQRPPTLQEIKQKIESYNAREKNCLGMKLSEDGSYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKDVDPAAATDKRTSFYLPLDAVKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADCPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKVQQVQKKYNKFRQKLEEALRKAQGKPA", "length": 423, "header": "tr|E1BN06-1|E1BN06_BOVIN Isoform 1 of Ras association domain-containing protein 5 OS=Bos taurus OX=9913 GN=RASSF5 PE=4 SV=2 CANONICAL=E1BN06-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MXG2-1", "url": "https://www.uniprot.org/uniprotkb/E1BN06/entry#A0A3Q1MXG2-1", "sequence": { "sequence": "MAMASPAIGQRPYRLLLEPEPPHYLQSLSDPEPLPPPPPPPPPGHSSRRCAPAPLSTAPGAHERRSAWRAARGDPEPQPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFVELALRGGRGWCDLCGREVWWRALSCANCKFTCHPECRSLIQLDCTQQDGANRDRPSPESTLAVTFSQNDCKPPEEPQRPPTLQEIKQKIESYNAREKNCLGMKLSEDGSYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKDVDPAAATDKRTSFYLPLDAVKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVGRLLHP", "length": 341, "header": "tr|A0A3Q1MXG2-1|E1BN06_BOVIN Computationally mapped isoform of Ras association domain-containing protein 5 OS=Bos taurus OX=9913 GN=RASSF5 PE=4 SV=2 CANONICAL=E1BN06-1" }, "locus": { "chromosome": "16", "start_pos": 4364723, "end_pos": 4293882, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069132.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069132.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060407.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060407.2" } ] } }, { "isoform_ac": "A0AAA9S6R7-1", "url": "https://www.uniprot.org/uniprotkb/E1BN06/entry#A0AAA9S6R7-1", "sequence": { "sequence": "MTEGRVEEAASACFGTITSQLQRLFHRLPKGHWRSLKPQALPGLRPNAQLARDCKFTCHPECRSLIQLDCTQQDGANRDRPSPESTLAVTFSQNDCKPPEEPQRPPTLQEIKQKIESYNAREKNCLGMKLSEDGSYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKDVDPAAATDKRTSFYLPLDAVKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADCPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKVQQVQKKYNKFRQKLEEALRKAQGKPA", "length": 318, "header": "tr|A0AAA9S6R7-1|E1BN06_BOVIN Computationally mapped isoform of Ras association domain-containing protein 5 OS=Bos taurus OX=9913 GN=RASSF5 PE=4 SV=1 CANONICAL=E1BN06-1" }, "locus": { "chromosome": "16", "start_pos": 4364853, "end_pos": 4304896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117748.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117748.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077856.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077856.1" } ] } }, { "isoform_ac": "A0AAA9T3N8-1", "url": "https://www.uniprot.org/uniprotkb/E1BN06/entry#A0AAA9T3N8-1", "sequence": { "sequence": "MTVDSSMSSGYCSLEEELEDCFFTAKTTFFRNVQSKRPSKNDCKPPEEPQRPPTLQEIKQKIESYNAREKNCLGMKLSEDGSYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKDVDPAAATDKRTSFYLPLDAVKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADCPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKVQQVQKKYNKFRQKLEEALRKAQGKPA", "length": 265, "header": "tr|A0AAA9T3N8-1|E1BN06_BOVIN Computationally mapped isoform of Ras association domain-containing protein 5 OS=Bos taurus OX=9913 GN=RASSF5 PE=4 SV=1 CANONICAL=E1BN06-1" }, "locus": { "chromosome": "16", "start_pos": 4364853, "end_pos": 4336380, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127155.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127155.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091102.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091102.1" } ] } }, { "isoform_ac": "A0ABI0NS28-1", "url": "https://www.uniprot.org/uniprotkb/E1BN06/entry#A0ABI0NS28-1", "sequence": { "sequence": "MAMASPAIGQRPYRLLLEPEPPHYLQSLSDPEPLPPPPPPPPPGHSSRRCAPAPLSTAPGAHERRSAWRAARGDPEPQPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFVELALRGGRGWCDLCGREVWWRALSCANCKFTCHPECRSLIQLDCTQQDGANRDRPSPESTLAVTFSQNDCKPPEEPQRPPTLQEIKQKIESYNAREKNCLGMKLSEDGSYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKDVDPAAATDKRTSFYLPLDAVKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQGRSEPPQKLPFPTLAGRARS", "length": 354, "header": "tr|A0ABI0NS28-1|A0ABI0NS28_BOVIN Computationally mapped isoform of Ras association domain family member 5 OS=Bos taurus OX=9913 GN=RASSF5 PE=4 SV=1 CANONICAL=E1BN06-1" }, "locus": { "chromosome": "16", "start_pos": 4362271, "end_pos": 4293882, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140194.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140194.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105700.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105700.1" } ] } }, { "isoform_ac": "E1BN06-1", "url": "https://www.uniprot.org/uniprotkb/E1BN06/entry#E1BN06-1", "sequence": { "sequence": "MAMASPAIGQRPYRLLLEPEPPHYLQSLSDPEPLPPPPPPPPPGHSSRRCAPAPLSTAPGAHERRSAWRAARGDPEPQPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFVELALRGGRGWCDLCGREVWWRALSCANCKFTCHPECRSLIQLDCTQQDGANRDRPSPESTLAVTFSQNDCKPPEEPQRPPTLQEIKQKIESYNAREKNCLGMKLSEDGSYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKDVDPAAATDKRTSFYLPLDAVKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADCPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKVQQVQKKYNKFRQKLEEALRKAQGKPA", "length": 423, "header": "tr|E1BN06-1|E1BN06_BOVIN Isoform 1 of Ras association domain-containing protein 5 OS=Bos taurus OX=9913 GN=RASSF5 PE=4 SV=2 CANONICAL=E1BN06-1" }, "locus": { "chromosome": "16", "start_pos": 4364853, "end_pos": 4293882, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049612.5", "url": "https://www.ensembl.org/id/ENSBTAT00000049612.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046479.2", "url": "https://www.ensembl.org/id/ENSBTAP00000046479.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539767", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539767", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O35141-1", "protein_name": "Ras association domain-containing protein 5", "gene_name": "Rassf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPAIGQRPYPLLLDPEPPRYLQSLGGTEPPPPARPRRCIPTALISASGASEGRGSRRNARGDPEPTPRDCRHARPVRPGLQQRLRRRPGSHRPRDVRSIFEQPQDPRVLAERGEGHRFAELALRGGPGWCDLCGREVLRQALRCANCKFTCHPECRSLIQLDCRQKEGPALDRQSPESTLTPTFNKNVCKAVEETQHPPTIQEIKQKIDSYNSREKHCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNPAATTDKRTSFYLPLDAIKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADCPLYLRLLAGPDTDVLSFVLKENETGDVEWDAFSIPELQNFLTILEKEEQDKIHQLQKKYNKFRQKLEEALRESQGKPG", "length": 413 }, "evidence": [ { "id": "E1BN06", "url": "https://omabrowser.org/oma/group/E1BN06/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5EBH1-1", "protein_name": "Ras association domain-containing protein 5", "gene_name": "Rassf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASPAIGQRPYPLLLDPEPPRYLQSLGGTEPPPPARPRRCIPTALIPAAGASEDRGGRRSGRRDPEPTPRDCRHARPVRPGLQPRLRLRPGSHRPRDVRSIFEQPQDPRVLAERGEGHRFVELALRGGPGWCDLCGREVLRQALRCANCKFTCHSECRSLIQLDCRQKGGPALDRRSPESTLTPTLNQNVCKAVEETQHPPTIQEIKQKIDSYNSREKHCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNPAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADYPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIHQLQKKYNKFRQKLEEALRESQGKPG", "length": 413 }, "evidence": [ { "id": "E1BN06", "url": "https://omabrowser.org/oma/group/E1BN06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WWW0-1", "protein_name": "Ras association domain-containing protein 5", "gene_name": "RASSF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRSARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG", "length": 418 }, "evidence": [ { "id": "E1BN06", "url": "https://omabrowser.org/oma/group/E1BN06/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "E1BN06", "url": "https://www.uniprot.org/uniprotkb/E1BN06" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BN06", "url": "https://www.uniprot.org/uniprotkb/E1BN06" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BN06", "url": "https://www.uniprot.org/uniprotkb/E1BN06" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1BN06", "url": "https://www.uniprot.org/uniprotkb/E1BN06" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BN06", "url": "https://www.uniprot.org/uniprotkb/E1BN06" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BN06", "url": "https://www.uniprot.org/uniprotkb/E1BN06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN06-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 423, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN06-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN06" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN06" }, { "id": "PS50081", "database": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMR4-1", "uniprot_ac": "E1BMR4", "uniprot_id": "E1BMR4_BOVIN", "mass": { "chemical_mass": 46193.0, "monoisotopic_mass": 46193.0 }, "refseq": { "ac": "XP_059733795", "name": "polycomb group RING finger protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059733795" }, "gene_names": [ { "name": "PCGF2", "type": "recommended", "evidence": [ { "id": "E1BMR4", "database": 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"https://www.uniprot.org/uniprotkb/E1BMR4/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 144", "type": "synonym", "evidence": [ { "id": "E1BMR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR4/entry#names_and_taxonomy" } ] }, { "name": "polycomb group RING finger protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059733795", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059733795" } ] } ], "function": [ { "annotation": "Transcriptional repressor. Binds specifically to the DNA sequence 5'-GACTNGACT-3'. Has tumor suppressor activity. May play a role in control of cell proliferation and/or neural cell development. Regulates proliferation of early T progenitor cells by maintaining expression of HES1. Also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.", "evidence": [ { "database": "UniProtKB", "id": "E1BMR4", "url": "https://www.uniprot.org/uniprotkb/E1BMR4#function" }, { "database": "UniProtKB", "id": "ARBA00057474", "url": "https://www.uniprot.org/uniprotkb/ARBA00057474#function" }, { "database": "UniProtKB", "id": "A0A3Q1N0I5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N0I5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMR4", "url": "https://www.uniprot.org/uniprotkb/E1BMR4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PCGF2", "url": "https://www.uniprot.org/uniprotkb/E1BMR4", "locus": { "chromosome": "19", "start_pos": 39328390, "end_pos": 39340181, "strand": "+", "evidence": [ { "database": "Ensembl Gene", 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BMR4", "url": "https://www.orthodb.org/?gene=E1BMR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10825", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10825", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10825:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10825:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4570464", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4570464", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8953750", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8953750", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"MKITRTRGQKRRVPRPSTAPFGRGRDVEDCRASHISVESSSHQFPGAPARGEDRRVWGKGVRTHILGTEGDAPHPSTMHRTTRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGVRDREEKKGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDVPSKYKVEVLYEDEPLKEYYTLMDIAYIYPWRRNGPLPLKYRVQPACKRLTLPTAPTPSEGTNTSGASECESVSDKAPSPATLPATSSSLPSPATPSHGSPSSHGPSAPHPTSPAPPVTAGGATAAANGGTSNCLQTPSSTSRGRKMTVNGAPVPPLT", "length": 421, "header": "tr|E1BMR4-1|E1BMR4_BOVIN Isoform 1 of Polycomb group RING finger protein 2 OS=Bos taurus OX=9913 GN=PCGF2 PE=4 SV=3 CANONICAL=E1BMR4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N0I5-1", "url": "https://www.uniprot.org/uniprotkb/E1BMR4/entry#A0A3Q1N0I5-1", "sequence": { "sequence": "MHRTTRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGVRDREEKKGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDVPSKYKVEVLYEDEPLKEYYTLMDIAYIYPWRRNGPLPLKYRVQPACKRLTLPTAPTPSEGTNTSGASEYTILHQQGAQDDCQRSSCAPLNLRKGTLSLFFQPCLSTPPLFLGPLFHLFYFPQLLPP", "length": 313, "header": "tr|A0A3Q1N0I5-1|E1BMR4_BOVIN Computationally mapped isoform of Polycomb group RING finger protein 2 OS=Bos taurus OX=9913 GN=PCGF2 PE=4 SV=1 CANONICAL=E1BMR4-1" }, "locus": { "chromosome": "19", "start_pos": 39333410, "end_pos": 39329585, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077318.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077318.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062214.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062214.2" } ] } }, { "isoform_ac": "E1BMR4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMR4/entry#E1BMR4-1", "sequence": { "sequence": "MKITRTRGQKRRVPRPSTAPFGRGRDVEDCRASHISVESSSHQFPGAPARGEDRRVWGKGVRTHILGTEGDAPHPSTMHRTTRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGVRDREEKKGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDVPSKYKVEVLYEDEPLKEYYTLMDIAYIYPWRRNGPLPLKYRVQPACKRLTLPTAPTPSEGTNTSGASECESVSDKAPSPATLPATSSSLPSPATPSHGSPSSHGPSAPHPTSPAPPVTAGGATAAANGGTSNCLQTPSSTSRGRKMTVNGAPVPPLT", "length": 421, "header": "tr|E1BMR4-1|E1BMR4_BOVIN Isoform 1 of Polycomb group RING finger protein 2 OS=Bos taurus OX=9913 GN=PCGF2 PE=4 SV=3 CANONICAL=E1BMR4-1" }, "locus": { "chromosome": "19", "start_pos": 39340121, "end_pos": 39329692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015331.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015331.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015331.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015331.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 320, "start_aa": "Thr", "end_pos": 320, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr320", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 358, "start_aa": "Thr", "end_pos": 358, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr358", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-BTA-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" }, { "id": "R-BTA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-BTA-4570464", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4570464", "resource": "Reactome", "description": "SUMOylation of RNA binding proteins" }, { "id": "R-BTA-8953750", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8953750", "resource": "Reactome", 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"interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLB7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 241, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLB7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLB7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB7" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 111, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNE2-1", "uniprot_ac": "E1BNE2", "uniprot_id": "E1BNE2_BOVIN", "mass": { "chemical_mass": 134695.0, "monoisotopic_mass": 134695.0 }, "refseq": { "ac": "XP_024838612", "name": "cullin-associated NEDD8-dissociated protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838612" }, "gene_names": [ { "name": "CAND2", "type": "recommended", "evidence": [ { "id": "E1BNE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE2" } ] }, { "name": "CAND2", "type": "synonym", "evidence": [ { "id": "XP_024838612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838612" } ] } ], "protein_names": [ { "name": "Cullin associated and neddylation dissociated 2 (putative)", "type": "synonym", "evidence": [ { "id": "E1BNE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE2/entry#names_and_taxonomy" } ] }, { "name": "cullin-associated NEDD8-dissociated protein 2", "type": "synonym", "evidence": [ { "id": "XP_024838612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838612" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNE2", "url": "https://www.uniprot.org/uniprotkb/E1BNE2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CAND2", "url": "https://www.uniprot.org/uniprotkb/E1BNE2", "locus": { "chromosome": "22", "start_pos": 56348725, "end_pos": 56377398, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015273", "url": "https://www.ensembl.org/id/ENSBTAG00000015273" } ] } } ], "crossref": [ { "id": "E1BNE2", "url": "https://alphafold.ebi.ac.uk/entry/E1BNE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015273", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015273", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "533826", "url": "https://www.ncbi.nlm.nih.gov/gene/533826", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WKLRMWA", "url": "https://omabrowser.org/oma/group/WKLRMWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12696", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12696", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08623", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08623", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024838612", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838612", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RVX5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVX5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNE2", "url": "https://www.uniprot.org/uniprotkb/E1BNE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNE2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQNLAVKCLGPLVGKVKEYQVETIVDVLCANMRSDKEQLRDIAGIGLKTVLSELPTAATGSSLASNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGAPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDQLPGPRAPASPTAIRTLIQCLGSIGRQAGHRLGAHLDRLVPLVEEFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNVTSLCLQYVKHDPNYNYDSDEDEEQMETEDSEFSEQESEEEYSDDDDMSWKVRRAAAKCLAALIDSRPDLLPDFHCALAPALIQRFKEREENVKADVFGAYIVLLRQTRPPKGWLEVMEEPTQTSSNLQMLRGQVPLVMKALQRQLKDRSARARQGCFSLLTELAGVLPGSLAEHMPVLVAGIVFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFQPHLPTLLPPVMACVADPFYKIAAEALLVLQELVRALWPLDGPRKLDPEPYVGEMSAATLARLRATDLDQEVKERAISCMGHLVGHLGDRLGGDLEPSLSLLLDRLRNEITRLSAVKALTLVAMSPLKISLQPILAEALPILASFLRKNQRALRLTTLAALAALAQSQGPGLPPSAVRAVLAELPALVSESDMHVAQLAVDFLATVTRAQPASMAEVSGPVLAELLRLLRSPLLPAGVLAATEGFLQALVGTRPPCVDYAKLIGLLTAPVYEQAAEGGPGLHKQVFHSLARCVAALAAACPQEAAGTANRLVGEARSPSSSPGVKVLAFLSLAEVGQVAGPGPQRELKAVLLEALGSPSEDVRAAASYALGRVGAGNLPDFLPFLLGQMEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAECIGKLVLVNPPFLLPRFRKQLAAGRPHTRCTVITAVKYLISDQPHPIDPLLKTFIGEFMESLQDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPFLYQETKIRRDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDVCEFLNHVEDGLKDHYDIRMLTFIMLARLATLCPVPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKSPIMADFSSQIRSNPELAALFESIQKDSVSAPSTDSMELS", "length": 1236, "header": "tr|E1BNE2-1|E1BNE2_BOVIN Isoform 1 of Cullin associated and neddylation dissociated 2 (putative) OS=Bos taurus OX=9913 GN=CAND2 PE=3 SV=3 CANONICAL=E1BNE2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RVX5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNE2/entry#A0AAA9RVX5-1", "sequence": { "sequence": "MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQNLAVKCCRVPFYLGPLGCHNGEEARSPGEGRCLAQAARRVGPAR", "length": 109, "header": "tr|A0AAA9RVX5-1|E1BNE2_BOVIN Computationally mapped isoform of Cullin associated and neddylation dissociated 2 (putative) OS=Bos taurus OX=9913 GN=CAND2 PE=3 SV=1 CANONICAL=E1BNE2-1" }, "locus": { "chromosome": "22", "start_pos": 56377345, "end_pos": 56366427, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097119.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097119.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075166.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075166.1" } ] } }, { "isoform_ac": "E1BNE2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNE2/entry#E1BNE2-1", "sequence": { "sequence": "MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQNLAVKCLGPLVGKVKEYQVETIVDVLCANMRSDKEQLRDIAGIGLKTVLSELPTAATGSSLASNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGAPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDQLPGPRAPASPTAIRTLIQCLGSIGRQAGHRLGAHLDRLVPLVEEFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNVTSLCLQYVKHDPNYNYDSDEDEEQMETEDSEFSEQESEEEYSDDDDMSWKVRRAAAKCLAALIDSRPDLLPDFHCALAPALIQRFKEREENVKADVFGAYIVLLRQTRPPKGWLEVMEEPTQTSSNLQMLRGQVPLVMKALQRQLKDRSARARQGCFSLLTELAGVLPGSLAEHMPVLVAGIVFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFQPHLPTLLPPVMACVADPFYKIAAEALLVLQELVRALWPLDGPRKLDPEPYVGEMSAATLARLRATDLDQEVKERAISCMGHLVGHLGDRLGGDLEPSLSLLLDRLRNEITRLSAVKALTLVAMSPLKISLQPILAEALPILASFLRKNQRALRLTTLAALAALAQSQGPGLPPSAVRAVLAELPALVSESDMHVAQLAVDFLATVTRAQPASMAEVSGPVLAELLRLLRSPLLPAGVLAATEGFLQALVGTRPPCVDYAKLIGLLTAPVYEQAAEGGPGLHKQVFHSLARCVAALAAACPQEAAGTANRLVGEARSPSSSPGVKVLAFLSLAEVGQVAGPGPQRELKAVLLEALGSPSEDVRAAASYALGRVGAGNLPDFLPFLLGQMEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAECIGKLVLVNPPFLLPRFRKQLAAGRPHTRCTVITAVKYLISDQPHPIDPLLKTFIGEFMESLQDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPFLYQETKIRRDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDVCEFLNHVEDGLKDHYDIRMLTFIMLARLATLCPVPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKSPIMADFSSQIRSNPELAALFESIQKDSVSAPSTDSMELS", "length": 1236, "header": "tr|E1BNE2-1|E1BNE2_BOVIN Isoform 1 of Cullin associated and neddylation dissociated 2 (putative) OS=Bos taurus OX=9913 GN=CAND2 PE=3 SV=3 CANONICAL=E1BNE2-1" }, "locus": { "chromosome": "22", "start_pos": 56377345, "end_pos": 56349729, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044086.5", "url": "https://www.ensembl.org/id/ENSBTAT00000044086.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041599.4", "url": "https://www.ensembl.org/id/ENSBTAP00000041599.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1SQ89-1", "protein_name": "Cullin associated and neddylation dissociated 2 (putative)", "gene_name": "CAND2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQNLAVKCLGPLVGKVKEYQVETIVDALCANMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGAPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFTELADHLLDRLPGPRAPTSPAALRTVIQCLGSVGRQAGHRLGAHLDRLVPLVEEFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCLAALIGSRPDLLHDFHCTLAPVLIRRFKEREENVKADVFGAYIVLLRQTRPPKGWLEGVEEPTQTGSNLHILRGQVPLVIKALQRQLKDRSIRARQGCFSLLTELAGVLPGSLAEHMPVLVAGIVFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHTHLPTLLPPVMACVADPFYKIAAEALLVLQELVKALWPLDRPRTLDPEPYIGEMSAATLARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPSLLLLLDRLRNEITRLSAVKALTLVAVSPLRIDLQLILAEALPILASFLRKNQRALRLATLAALDALARSQGLSLPPPAVRTVLAELPALVSESDMHVAQLAVDFLATVTHAQPASLAEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVNYAELISLLTAPVYNQPVDSGPGLHKQVFHSLARCVAALAAACPQEAAGTAKRLVCDARSPSSSTGVKVLAFLSLAEVGQVAGPGPQRELKAVLLEALGSPSEDVRAAASYALGRVGAGNLPDFLPFLLGQIEAEPRRQYLLLHSLREALGAAPPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAECIGKLVLVNPPFLLPRFRKQLAAGQPHTRSTVITAVKFLISDQPHPIDPLLKSFIGEFMESLQDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHLEDGLKDHYDIRMLTFIMLARLATLCPVPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKSPIMADFSSQIRSNPELTTLFESIQKDSASAPSTDSMELS", "length": 1236 }, "evidence": [ { "id": "E1BNE2", "url": "https://omabrowser.org/oma/group/E1BNE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75155-1", "protein_name": "Cullin-associated NEDD8-dissociated protein 2", "gene_name": "CAND2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQNLAVKCLGPLVVKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGVPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLLRQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQLDLQPILAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHPIDPLLKSFIGEFMESLQDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMVARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKSPIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS", "length": 1236 }, "evidence": [ { "id": "E1BNE2", "url": "https://omabrowser.org/oma/group/E1BNE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ZQ73-1", "protein_name": "Cullin-associated NEDD8-dissociated protein 2", "gene_name": "Cand2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTGAFYISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVRTLLRLLEDRSGEVQNLAVKCLGPLVGKVKEYQVENIVDTLCANMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLAINVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGAPLGTFHASLLHCLLPQLSSPRLAVRKRTVVALGHLAAACSTDLFVELADHLVDRLPGPRAPASPAAIRTLIQCLGSVGRQAGHRLGAHLDRLVPMVEEFCNLDDDELRESCLQAFEAFLRKCPKEMDPHVPNVTSLCLQYMKHDPNYDHDSDDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCMAALISSRPDLLPDFHCTLAPALIRRFKEREENVKADIFGAYIMLLRHTRPPKGWLEAVEEPTQTGRNLNMLRAQVPLVIKALQRQLKDRNVRTRQGCFNLFTELAGVLPGSLAEHMAVLVSGIVFSLADYSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPTLLPPVMACVADPFYKVAAEALLVLQELVRTLWPLDRPRLLDPEPYVGEMSTATLARLRATDLDQEVKERAISCVGHLVGHLGDRLGDDLEPTLMLLLDRLRNEITRLPAVKALTLVAMSPLRLDLQPILAEALPILASFLRKNQRALRLATLAALDALAQSQGLGLPPPAVRTVLTELPALVSENDMHVAQLAVDFLTTVTQTQPSSLVEVSGPVLGELLQLLHSPLLPAGVLAATEGFLQALVGTRPPCVEYSELISLLTAPVYNQVGDGGPGLHKQVFHSLARCVAALSAACPQEAAGTASRLVCDAKSPHSSTGVKVLAFLSLAEVGQVAGPGPQRELKTVLLEALGSPSEDVRAAAAYALGRVGAGNLPDFLPFLLAQIEAQPRRQYLLLHALREALGAAQPDNLKPYVEDVWALLFQRCESPEEGTRCVVAECIGKLVFVNPPYLLPRFRKQLAAGQPYTRSTVITAVKFLISDQPHSIDPLLKSFIAEFMESLQDPDLNVRRATLTFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDMCEFLNHVEDGLKDHYDIRMLTFIMLARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQELEKQEELKRSAMRAVAALLTNPEVRKSPTVADFSAQIRSNPELTTLFESIQKDTASGPSTDSMELS", "length": 1235 }, "evidence": [ { "id": "E1BNE2", "url": "https://omabrowser.org/oma/group/E1BNE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9R0L4-1", "protein_name": "Cullin-associated NEDD8-dissociated protein 2", "gene_name": "Cand2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTGAFYISSLLEKMTSSDKDFSPKSLGGSRVLDPLPWLQILAAITDWISGDRTQDLALPRFMATSDLMSELQKDSIQLDEDSERKVVRTLLRLLEDRSGEVQNLAVKCLGPLVGKVKEYQVENIVDTLCANMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLAISVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGAPLGTFHASLLHCLLPQLSSPRLAVRKRTVVALGHLAAACSTDLFVELADHLVDRLPGPRAPASPAAIRTLIQCLGSVGRQAGHRLGAHLDRLMPLVEEFCNLDDDELRESCLQAFEAFLRKCPKEMDPHVPNVTSLCLQYMKHDPNYNHDSDEEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCMAALISSRPDLLPDFHCTLAPALIRCFKEREENVKADIFGAYIMLLRHTRPPKGWLEAVEEPTQTGRNLNMLRAQVPLVMKALQRQLKDRNVRTRQGCFNLFTELAGVLPGCLAEHMTVLVSGIVFSLADYSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPTLLPPVMACVADPFYKVAAEALLVLQELVRTLWPLDRPRLLDPEPYVGEMSTATLARLRATDLDQEVKERAISCVGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAVKALTLVAVSPLRLDLQPILAEALPILASFLRKNQRALRLATLAALDALAQSQGLGLPPPAVRSVLAELPALVSENDMHVAQLAVDFLTTVTQTQPASLVEVSGPVLEELLQLLHSPLLPAGVLAATEGFLQALVGTRPPCVEYSELISLLTAPVYNQVGDGGPGLHKQVFHSLARCVAALSAACPQEAAGTASRLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGPQRELKTVLLEALGSPSEDVRAAAAYALGRVGAGNLPDFLPFLLAQIEAQPRRQYLLLHALREALGAAQPDNLKPYVEDVWALLFQRCESPEEGTRCVVAECIGKLVFVNPPFLLPRFRKQLAAGQPYTRSTVITAVKFLISDQPHSIDPLLKSFIAEFMESLQDPDLNVRRATLTFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMLARLAALCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQELEKQDELKRSAMRAVAALMTNPEVRKSPSVADFSTQIRSNPELATLFESIQKDTASGPSMDSMELS", "length": 1273 }, "evidence": [ { "id": "E1BNE2", "url": "https://omabrowser.org/oma/group/E1BNE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "SCF complex assembly", "id": "GO:0010265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010265", "evidence": [ { "database": "UniProtKB", "id": "E1BNE2", "url": "https://www.uniprot.org/uniprotkb/E1BNE2" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BNE2", "url": "https://www.uniprot.org/uniprotkb/E1BNE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BNE2", "url": "https://www.uniprot.org/uniprotkb/E1BNE2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BNE2", "url": "https://www.uniprot.org/uniprotkb/E1BNE2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "E1BNE2", "url": "https://www.uniprot.org/uniprotkb/E1BNE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNE2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1236, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNE2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNE2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE2" }, { "id": "PF08623", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08623" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TATA-binding protein interacting (TIP20)", "eco_id": "ECO_0000259", "start_pos": 1045, "end_pos": 1207, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 299, "end_pos": 301 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNA6-1", "uniprot_ac": "E1BNA6", "uniprot_id": "E1BNA6_BOVIN", "mass": { "chemical_mass": 241922.0, "monoisotopic_mass": 241922.0 }, "refseq": { "ac": "XP_059744914", "name": "dedicator of cytokinesis protein 8 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059744914" }, "gene_names": [ { "name": "DOCK8", "type": "recommended", "evidence": [ { "id": "E1BNA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA6" } ] }, { "name": "DOCK8", "type": "synonym", "evidence": [ { "id": "XP_059744914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059744914" } ] } ], "protein_names": [ { "name": "Dedicator of cytokinesis 8", "type": "synonym", "evidence": [ { "id": "E1BNA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA6/entry#names_and_taxonomy" } ] }, { "name": "dedicator of cytokinesis protein 8 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059744914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059744914" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNA6", "url": "https://www.uniprot.org/uniprotkb/E1BNA6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DOCK8", "url": "https://www.uniprot.org/uniprotkb/E1BNA6", "locus": { "chromosome": "8", "start_pos": 44032278, "end_pos": 44271335, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002190", "url": "https://www.ensembl.org/id/ENSBTAG00000002190" } ] } } ], "crossref": [ { "id": 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"url": "https://www.uniprot.org/uniprotkb/A0AAA9S7C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7C1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SE24", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SE24-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQT6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQT6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7K4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7K4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNA6", "url": "https://www.uniprot.org/uniprotkb/E1BNA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNA6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATLPSAERRAFALKINRYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSLQLKFGNLPLSFLQPPFCLLWQFPRRVTVCLSKPQFYDPVEPVDFEGLLMTHLNSLDVELAQELGDFSEDDLDVAFTPKECRTLQPSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSSEVCSFKKIGSRKDFHKTLQKQTFESETLECSEPSAQAGPRHLSVLCDVSGKGPNTACDFDLRSLQPDPRLENLVQQVSAEDFEKQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVASSSQARSAVFSVTYPSSDIYLVAKIEKVLQQGEIGDCAEPYMVIKESDGGKSKDKIEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNVSTLDREVTDVESMVGKGSAGERRTLSQSRRLSERAFSLEENGVGSNFKTLTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGLLKLEISLAPETINCCLTPEMLPVRPFPENRGRPHKEILEFPIREVYVPHTVYRNLLYVYPQRLNFANKLASARNITIKIQFMCGEDASSAMPVIFGKSNGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGNSVESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPSQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISESALEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLFVQPMVIAGQPANFSQFAFESVVVTANSLHNSKGLGKDQHGRNCLLASYVHYVFRLPEPQRDMPKSGGPTVLPDPRYHTYGRTSAAAVSSKLLQARVMSSSNPDLAGPHCAADEEVKSIMSSKIADRSCNRMSYYCSSNSDAPSSTTAPRPVSKKHFHEELALQMVVSTGMVKETVFKYSWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKETEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAAALDAEGEGIIKVQRKAVSAIHSLLSSHDLDPRCVKPEVKVKVAALYLPLVGIILDALPQLYDFTAAEARGGKNRANGSDEEQEGTSAINQNVALAIAGNFNLKTSTTMLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQTLLRKWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRTPGNDRFPGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENIIQASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCADLCQRVLHHCSSSMDITRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAQDFNEEYLRRSLRTILAYAEEDTAMQTTPFPMQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHEKLQKAFDSIISKGHKRMFGTYFRVGFYGSKFGDLDEKEFVYKEPAITKLPEISHRLEAFYSQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRLTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTILTTLHAFPYIKTRISVAQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLRENLRPMIERKIPELYKPIFRVDSQKRDSFHRSSFRKCETQLSQGS", "length": 2128, "header": "tr|E1BNA6-1|E1BNA6_BOVIN Isoform 1 of Dedicator of cytokinesis 8 OS=Bos taurus OX=9913 GN=DOCK8 PE=3 SV=3 CANONICAL=E1BNA6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RY79-1", "url": "https://www.uniprot.org/uniprotkb/E1BNA6/entry#A0AAA9RY79-1", "sequence": { "sequence": "MYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSLQLPQFYDPVEPVDFEGLLMTHLNSLDVELAQELGDFSEDDLDVAFTPKECRTLQPSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSSEVCSFKKIGSRKDFHKTLQKQTFESETLECSEPSAQAGPRHLSVLCDVSGKGPNTACDFDLRSLQPDPRLENLVQQVSAEDFEKQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVASSSQARSAVFSVTYPSSDIYLVAKIEKVLQQGEIGDCAEPYMVIKESDGGKSKDKIEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNVSTLDREVTDVESMVGKGSAGERRTLSQSRRLSERAFSLEENGVGSNFKTLTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGLLKLEISLAPETINCCLTPEMLPVRPFPENRGRPHKEILEFPIREVYVPHTVYRNLLYVYPQRLNFANKLASARNITIKIQFMCGEDASSAMPVIFGKSNGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGNSVESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPSQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISESALEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLFVQPMVIAGQPANFSQFAFESVVVTANSLHNSKGLGKDQHGRNCLLASYVHYVFRLPEPQRDMPKSGGPTVLPDPRYHTYGRTSAAAVSSKLLQARVMSSSNPDLAGPHCAADEEVKSIMSSKIADRSCNRMSYYCSSNSDAPSSTTAPRPVSKKHFHEELALQMVVSTGMVKETVFKYSWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKETEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAAALDAEGEGIIKVQRKAVSAIHSLLSSHDLDPRCVKPEVKVKVAALYLPLVGIILDALPQLYDFTAAEARGGKNRANGSDEEQEGTSAINQNVALAIAGNFNLKTSTTMLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQTLLRKWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRTPGNDRFPGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENIIQASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCADLCQRVLHHCSSSMDITRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAQDFNEEYLRRSLRTILAYAEEDTAMQTTPFPMQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHEKLQKAFDSIISKGHKRMFGTYFRVGFYGSKFGDLDEKEFVYKEPAITKLPEISHRLEAFYSQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRLTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTILTTLHAFPYIKTRISVAQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLRENLRPMIERKIPELYKPIFRVDSQKRDSFHRSSFRKCETQLSQGS", "length": 2081, "header": "tr|A0AAA9RY79-1|E1BNA6_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 8 OS=Bos taurus OX=9913 GN=DOCK8 PE=3 SV=1 CANONICAL=E1BNA6-1" }, "locus": { "chromosome": "8", "start_pos": 44270363, "end_pos": 44033269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114300.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114300.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076207.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076207.1" } ] } }, { "isoform_ac": "A0AAA9S0T7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNA6/entry#A0AAA9S0T7-1", "sequence": { "sequence": "MATLPSAERRAFALKINRYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSLQLPQFYDPVEPVDFEGLLMTHLNSLDVELAQELGDFSEDDLDVAFTPKECRTLQPSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSSEVCSFKKIGSRKDFHKTLQKQTFESETLECSEPSAQAGPRHLSVLCDVSGKGPNTACDFDLRSLQPDPRLENLVQQVSAEDFEKQNEEARRTNRQAELFALYPSVDEFPDGGANR", "length": 255, "header": "tr|A0AAA9S0T7-1|E1BNA6_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 8 OS=Bos taurus OX=9913 GN=DOCK8 PE=3 SV=1 CANONICAL=E1BNA6-1" }, "locus": { "chromosome": "8", "start_pos": 44271136, "end_pos": 44176312, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133203.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133203.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078587.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078587.1" } ] } }, { "isoform_ac": "A0AAA9S7C1-1", "url": "https://www.uniprot.org/uniprotkb/E1BNA6/entry#A0AAA9S7C1-1", "sequence": { "sequence": "MATLPSAERRAFALKINRNQGSSEVCSFKKIGSRKDFHKTLQKQTFESETLECSEPSAQAGPRHLSVLCDVSGKGPNTACDFDLRSLQPDPRLENLVQQVSAEDFEKQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVASSSQARSAVFSVTYPSSDIYLVAKIEKVLQQGEIGDCAEPYMVIKESDGGKSKDKIEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNVSTLDREVTDVESMVGKGSAGERRTLSQSRRLSERAFSLEENGVGSNFKTLTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGLLKLEISLAPETINCCLTPEMLPVRPFPENRGRPHKEILEFPIREVYVPHTVYRNLLYVYPQRLNFANKLASARNITIKIQFMCGEDASSAMPVIFGKSNGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGNSVESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPSQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISESALEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLFVQPMVIAGQPANFSQFAFESVVVTANSLHNSKGLGKDQHGRNCLLASYVHYVFRLPEPQRDMPKSGGPTVLPDPRYHTYGRTSAAAVSSKLLQARVMSSSNPDLAGPHCAADEEVKSIMSSKIADRSCNRMSYYCSSNSDAPSSTTAPRPVSKKHFHEELALQMVVSTGMVKETVFKYSWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKETEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAAALDAEGEGIIKVQRKAVSAIHSLLSSHDLDPRCVKPEVKVKVAALYLPLVGIILDALPQLYDFTAAEARGGKNRANGSDEEQEGTSAINQNVALAIAGNFNLKTSTTMLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQTLLRKWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRTPGNDRFPGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENIIQASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCADLCQRVLHHCSSSMDITRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAQDFNEEYLRRSLRTILAYAEEDTAMQTTPFPMQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHEKLQKAFDSIISKGHKRMFGTYFRVGFYGSKFGDLDEKEFVYKEPAITKLPEISHRLEAFYSQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRLTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTILTTLHAFPYIKTRISVAQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLRENLRPMIERKIPELYKPIFRVDSQKRDSFHRSSFRKCETQLSQGS", "length": 1981, "header": "tr|A0AAA9S7C1-1|E1BNA6_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 8 OS=Bos taurus OX=9913 GN=DOCK8 PE=3 SV=1 CANONICAL=E1BNA6-1" }, "locus": { "chromosome": "8", "start_pos": 44271136, "end_pos": 44033269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094636.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094636.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081898.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081898.1" } ] } }, { "isoform_ac": "A0AAA9SE24-1", "url": "https://www.uniprot.org/uniprotkb/E1BNA6/entry#A0AAA9SE24-1", "sequence": { "sequence": "MYPSSPEPPSHPGCRRTRNRIPCGIQYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSLQLPQFYDPVEPVDFEGLLMTHLNSLDVELAQELGDFSEDDLDVAFTPKECRTLQPSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSSEVCSFKKIGSRKDFHKTLQKQTFESETLECSEPSAQAGPRHLSVLCDVSGKGPNTACDFDLRSLQPDPRLENLVQQVSAEDFEKQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVASSSQARSAVFSVTYPSSDIYLVAKIEKVLQQGEIGDCAEPYMVIKESDGGKSKDKIEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNVSTLDREVTDVESMVGKGSAGERRTLSQSRRLSERAFSLEENGVGSNFKTLTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGLLKLEISLAPETINCCLTPEMLPVRPFPENRGRPHKEILEFPIREVYVPHTVYRNLLYVYPQRLNFANKLASARNITIKIQFMCGEDASSAMPVIFGKSNGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGNSVESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPSQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISESALEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLFVQPMVIAGQPANFSQFAFESVVVTANSLHNSKGLGKDQHGRNCLLASYVHYVFRLPEPQRDMPKSGGPTVLPDPRYHTYGRTSAAAVSSKLLQARVMSSSNPDLAGPHCAADEEVKSIMSSKIADRSCNRMSYYCSSNSDAPSSTTAPRPVSKKHFHEELALQMVVSTGMVKETVFKYSWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKETEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAAALDAEGEGIIKVQRKAVSAIHSLLSSHDLDPRCVKPEVKVKVAALYLPLVGIILDALPQLYDFTAAEARGGKNRANGSDEEQEGTSAINQNVALAIAGNFNLKTSTTMLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQTLLRKWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRTPGNDRFPGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENIIQASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCADLCQRVLHHCSSSMDITRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAQDFNEEYLRRSLRTILAYAEEDTAMQTTPFPMQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHEKLQKAFDSIISKGHKRMFGTYFRVGFYGSKFGDLDEKEFVYKEPAITKLPEISHRLEAFYSQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRLTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTILTTLHAFPYIKTRISVAQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLRENLRPMIERKIPELYKPIFRVDSQKRDSFHRSSFRKCETQLSQGS", "length": 2106, "header": "tr|A0AAA9SE24-1|E1BNA6_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 8 OS=Bos taurus OX=9913 GN=DOCK8 PE=3 SV=1 CANONICAL=E1BNA6-1" }, "locus": { "chromosome": "8", "start_pos": 44237219, "end_pos": 44033269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105060.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105060.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080633.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080633.1" } ] } }, { "isoform_ac": "A0AAA9SQT6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNA6/entry#A0AAA9SQT6-1", "sequence": { "sequence": "MGFSRQAYRSGSPCPLPRDLPNPGIQLEPPVAPALQKFGNLPLSFLQPPFCLLWQFPRRVTVCLSKPQFYDPVEPVDFEGLLMTHLNSLDVELAQELGDFSEDDLDVAFTPKECRTLQPSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSSEVCSFKKIGSRKDFHKTLQKQTFESETLECSEPSAQAGPRHLSVLCDVSGKGPNTACDFDLRSLQPDPRLENLVQQVSAEDFEKQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVASSSQARSAVFSVTYPSSDIYLVAKIEKVLQQGEIGDCAEPYMVIKESDGGKSKDKIEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNVSTLDREVTDVESMVGKGSAGERRTLSQSRRLSERAFSLEENGVGSNFKTLTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGLLKLEISLAPETINCCLTPEMLPVRPFPENRGRPHKEILEFPIREVYVPHTVYRNLLYVYPQRLNFANKLASARNITIKIQFMCGEDASSAMPVIFGKSNGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGNSVESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPSQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISESALEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLFVQPMVIAGQPANFSQFAFESVVVTANSLHNSKGLGKDQHGRNCLLASYVHYVFRLPEPQRDMPKSGGPTVLPDPRYHTYGRTSAAAVSSKLLQARVMSSSNPDLAGPHCAADEEVKSIMSSKIADRSCNRMSYYCSSNSDAPSSTTAPRPVSKKHFHEELALQMVVSTGMVKETVFKYSWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKETEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAAALDAEGEGIIKVQRKAVSAIHSLLSSHDLDPRCVKPEVKVKVAALYLPLVGIILDALPQLYDFTAAEARGGKNRANGSDEEQEGTSAINQNVALAIAGNFNLKTSTTMLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQTLLRKWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRTPGNDRFPGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENIIQASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCADLCQRVLHHCSSSMDITRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAQDFNEEYLRRSLRTILAYAEEDTAMQTTPFPMQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHEKLQKAFDSIISKGHKRMFGTYFRVGFYGSKFGDLDEKEFVYKEPAITKLPEISHRLEAFYSQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRLTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTILTTLHAFPYIKTRISVAQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLRENLRPMIERKIPELYKPIFRVDSQKRDSFHRSSFRKCETQLSQGS", "length": 2112, "header": "tr|A0AAA9SQT6-1|E1BNA6_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 8 OS=Bos taurus OX=9913 GN=DOCK8 PE=3 SV=1 CANONICAL=E1BNA6-1" }, "locus": { "chromosome": "8", "start_pos": 44217305, "end_pos": 44033269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100060.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100060.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085318.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085318.1" } ] } }, { "isoform_ac": "A0AAA9T7K4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNA6/entry#A0AAA9T7K4-1", "sequence": { "sequence": 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"length": 2066, "header": "tr|A0AAA9T7K4-1|E1BNA6_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 8 OS=Bos taurus OX=9913 GN=DOCK8 PE=3 SV=1 CANONICAL=E1BNA6-1" }, "locus": { "chromosome": "8", "start_pos": 44271136, "end_pos": 44033269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118564.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118564.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092578.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092578.1" } ] } }, { "isoform_ac": "E1BNA6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNA6/entry#E1BNA6-1", "sequence": { "sequence": 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"length": 2128, "header": "tr|E1BNA6-1|E1BNA6_BOVIN Isoform 1 of Dedicator of cytokinesis 8 OS=Bos taurus OX=9913 GN=DOCK8 PE=3 SV=3 CANONICAL=E1BNA6-1" }, "locus": { "chromosome": "8", "start_pos": 44271136, "end_pos": 44033269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002840.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002840.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002840.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002840.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-BTA-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" }, { "id": "R-BTA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E1BNA6", "url": "https://www.uniprot.org/uniprotkb/E1BNA6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "E1BNA6", "url": "https://www.uniprot.org/uniprotkb/E1BNA6" } ], "pmid": "" }, { "name": "positive regulation of establishment of T cell polarity", "id": "GO:1903905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903905", "evidence": [ { "database": "UniProtKB", "id": "E1BNA6", "url": "https://www.uniprot.org/uniprotkb/E1BNA6" } ], "pmid": "" }, { "name": "cellular response to chemokine", "id": "GO:1990869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990869", "evidence": [ { "database": "UniProtKB", "id": "E1BNA6", "url": "https://www.uniprot.org/uniprotkb/E1BNA6" } ], "pmid": "" }, { "name": "positive regulation of T cell migration", "id": "GO:2000406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000406", "evidence": [ { "database": "UniProtKB", "id": "E1BNA6", "url": "https://www.uniprot.org/uniprotkb/E1BNA6" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "E1BNA6", "url": "https://www.uniprot.org/uniprotkb/E1BNA6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BNA6", "url": "https://www.uniprot.org/uniprotkb/E1BNA6" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "E1BNA6", "url": "https://www.uniprot.org/uniprotkb/E1BNA6" } ], "pmid": "" }, { "name": "leading edge membrane", "id": "GO:0031256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031256", "evidence": [ { "database": "UniProtKB", "id": "E1BNA6", "url": "https://www.uniprot.org/uniprotkb/E1BNA6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1076, "end_pos": 1078, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1158, "end_pos": 1160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1272, "end_pos": 1274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNB4-1", "uniprot_ac": "E1BNB4", "uniprot_id": "E1BNB4_BOVIN", "mass": { "chemical_mass": 68653.0, "monoisotopic_mass": 68653.0 }, "refseq": { "ac": "XP_002692514", "name": "polyadenylate-binding protein 1-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692514" }, "gene_names": [ { "name": "PABPC1L", "type": "recommended", "evidence": [ { "id": "E1BNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB4" } ] }, { "name": "PABPC1L", "type": "synonym", "evidence": [ { "id": "XP_002692514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692514" } ] } ], "protein_names": [ { "name": "Polyadenylate-binding protein", "type": "recommended", "evidence": [ { "id": "E1BNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB4/entry#names_and_taxonomy" } ] }, { "name": "PABP", "type": "synonym", "evidence": [ { "id": "E1BNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB4/entry#names_and_taxonomy" } ] }, { "name": "polyadenylate-binding protein 1-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_002692514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692514" } ] } ], "function": [ { "annotation": "Binds the poly(A) tail of mRNA.", "evidence": [ { "database": "UniProtKB", "id": "E1BNB4", "url": "https://www.uniprot.org/uniprotkb/E1BNB4#function" }, { "database": "UniProtKB", "id": "RU362004", "url": "https://www.uniprot.org/uniprotkb/RU362004#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNB4", "url": "https://www.uniprot.org/uniprotkb/E1BNB4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PABPC1L", "url": "https://www.uniprot.org/uniprotkb/E1BNB4", "locus": { "chromosome": "13", "start_pos": 73345255, "end_pos": 73321863, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016849", "url": "https://www.ensembl.org/id/ENSBTAG00000016849" } ] } } ], "crossref": [ { "id": "E1BNB4", "url": "https://alphafold.ebi.ac.uk/entry/E1BNB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016849", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016849", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12378", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12379", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12379", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12380", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12380", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12381", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12381", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "509864", "url": "https://www.ncbi.nlm.nih.gov/gene/509864", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509864", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509864", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BNB4", "url": "https://www.orthodb.org/?gene=E1BNB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00658", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00658", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002692514", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692514", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S1D8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1D8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNB4", "url": "https://www.uniprot.org/uniprotkb/E1BNB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNB4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNASGPGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEVIKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVVCDEHGSRGFGFVHFETHEAAQNAISTMNGMLLNDRKVFVGHFKSRREREVELGARAMEFTNIYVKNLHVDVDEQRLQDLFSQFGKMLSVKVMRDDSGHSRGFGFVNFEKHEEAQKAVVNMNGREVSGRLLYVGRAQKRVERQNELKRRFEQMKQDRLTRYQGVNLYVKNLDDSIDDEKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQRLSTMRALGGPILGSFQQPASYFLPAVPQPPAQAPYYGSGPPIQPAPRWTAQPPRPSSAYPPGASVVRPAAMSRRPLTPVGSSRQVSTHVPHLVPHTQRVANIGTQTTGPSMTGCSTPSRPLLTHTYSTPAHRTDRVQEPAVHVPGQEPLTASVLAAAPLHEQKQMIGERLFPLVYNVHAHLAGKITGMLLEIDNSELLLMLESPESLNAKVEEALAVLQAHQATEHMQGVNLC", "length": 618, "header": "tr|E1BNB4-1|E1BNB4_BOVIN Isoform 1 of Polyadenylate-binding protein OS=Bos taurus OX=9913 GN=PABPC1L PE=3 SV=4 CANONICAL=E1BNB4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S1D8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNB4/entry#A0AAA9S1D8-1", "sequence": { "sequence": "MNASGPGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEVIKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVVCDEHGSRGFGFVHFETHEAAQNAISTMNGMLLNDRKVFVGHFKSRREREVELGARAMEFTNIYVKNLHVDVDEQRLQDLFSQFGKMLSVKVMRDDSGHSRGFGFVNFEKHEEAQKAVVNMNGREVSGRLLYVGRAQKRVERQNELKRRFEQMKQDRLTRYQVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQRLSTMRALGGPILGSFQQPASYFLPAVPQPPAQAPYYGSGPPIQPAPRWTAQPPRPSSAYPPGASVVRPAAMSRRPLTPVGSSRQVSTHVPHLVPHTQRVANIGTQTTGPSMTGCSTPSRPLLTHTYSTPAHRTDRVQEPAVHVPGQEPLTASVLAAAPLHEQKQMIGERLFPLVYNVHAHLAGKITGMLLEIDNSELLLMLESPESLNAKVEEALAVLQAHQATEHMQGVNLC", "length": 586, "header": "tr|A0AAA9S1D8-1|E1BNB4_BOVIN Computationally mapped isoform of Polyadenylate-binding protein OS=Bos taurus OX=9913 GN=PABPC1L PE=3 SV=1 CANONICAL=E1BNB4-1" }, "locus": { "chromosome": "13", "start_pos": 73345246, "end_pos": 73322062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123490.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123490.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077493.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077493.1" } ] } }, { "isoform_ac": "E1BNB4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNB4/entry#E1BNB4-1", "sequence": { "sequence": "MNASGPGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEVIKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVVCDEHGSRGFGFVHFETHEAAQNAISTMNGMLLNDRKVFVGHFKSRREREVELGARAMEFTNIYVKNLHVDVDEQRLQDLFSQFGKMLSVKVMRDDSGHSRGFGFVNFEKHEEAQKAVVNMNGREVSGRLLYVGRAQKRVERQNELKRRFEQMKQDRLTRYQGVNLYVKNLDDSIDDEKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQRLSTMRALGGPILGSFQQPASYFLPAVPQPPAQAPYYGSGPPIQPAPRWTAQPPRPSSAYPPGASVVRPAAMSRRPLTPVGSSRQVSTHVPHLVPHTQRVANIGTQTTGPSMTGCSTPSRPLLTHTYSTPAHRTDRVQEPAVHVPGQEPLTASVLAAAPLHEQKQMIGERLFPLVYNVHAHLAGKITGMLLEIDNSELLLMLESPESLNAKVEEALAVLQAHQATEHMQGVNLC", "length": 618, "header": "tr|E1BNB4-1|E1BNB4_BOVIN Isoform 1 of Polyadenylate-binding protein OS=Bos taurus OX=9913 GN=PABPC1L PE=3 SV=4 CANONICAL=E1BNB4-1" }, "locus": { "chromosome": "13", "start_pos": 73345246, "end_pos": 73322062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022412.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022412.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022412.7", "url": "https://www.ensembl.org/id/ENSBTAP00000022412.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509864", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509864", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BNB4", "url": "https://www.uniprot.org/uniprotkb/E1BNB4" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1BNB4", "url": "https://www.uniprot.org/uniprotkb/E1BNB4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BNB4", "url": "https://www.uniprot.org/uniprotkb/E1BNB4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BNB4", "url": "https://www.uniprot.org/uniprotkb/E1BNB4" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "E1BNB4", "url": "https://www.uniprot.org/uniprotkb/E1BNB4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "E1BNB4", "url": "https://www.uniprot.org/uniprotkb/E1BNB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNB4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 618, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNB4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNB4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB4" }, { "id": "PS51309", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51309" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PABC", "eco_id": "ECO_0000259", "start_pos": 531, "end_pos": 608, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB4" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 89, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 2, "end_pos": 4 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM66-1", "uniprot_ac": "E1BM66", "uniprot_id": "E1BM66_BOVIN", "mass": { "chemical_mass": 296640.0, "monoisotopic_mass": 296640.0 }, "refseq": { "ac": "XP_024850834", "name": "histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850834" }, "gene_names": [ { "name": "NSD1", "type": "recommended", "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ] }, { "name": "NSD1", "type": "synonym", "evidence": [ { "id": "XP_024850834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850834" } ] } ], "protein_names": [ { "name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "type": "recommended", "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.357", "type": "synonym", "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66/entry#names_and_taxonomy" } ] }, { "name": "H3-K36-HMTase", "type": "synonym", "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66/entry#names_and_taxonomy" } ] }, { "name": "Nuclear receptor-binding SET domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66/entry#names_and_taxonomy" } ] }, { "name": "histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024850834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850834" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NSD1", "url": "https://www.uniprot.org/uniprotkb/E1BM66", "locus": { "chromosome": "7", "start_pos": 38768519, "end_pos": 38619292, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025426", "url": "https://www.ensembl.org/id/ENSBTAG00000025426" } ] } } ], "crossref": [ { "id": "ENSBTAG00000025426", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000025426", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15648", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15648", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": 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] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047426", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047426", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CTKTAES", "url": "https://omabrowser.org/oma/group/CTKTAES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM66", "url": "https://www.orthodb.org/?gene=E1BM66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17982", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17982", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23011", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23011", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3214841", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214841", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024850834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850834", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "60308", "url": "https://www.rhea-db.org/rhea/60308", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S1J5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1J5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1J5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8D7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8D7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8D7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM66-1", "url": "https://www.uniprot.org/uniprotkb/E1BM66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTASGTSQNAYGQDSPSCYIPLRKLQDLASMINVEYLNGSADGSESFQDPEKSDSRAQSPVVCTSLNPGGPTALAMKQEPSCNNSPELQVKVTKTVKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYEPKSENGVDVAMGDEQDSTPDSRHGAGKPPFLPLAPQTETQRNKQRSDVDGSHEKAALLPAPLSLGDTNVTIEEQLNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKATPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDIPKGSKNRKCVTSSIKLDSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHMQFETHKEERRGKIPENLGLNFISGDVSDKQASNELSRIANSLTGPSTAPGSFLFSSCAKNTAKKEFETSNCDSLLGLSEGALISKRSGEKKKFQRGLMCSSKVQLCYIGAGDEEKRSDSISICTTSDDGSSDLDPVDHSSESDNSVLEITDAFDRSENLLPVQKNEKVKYSRYPATNTKVKAKQKSLITNSHTDHLINCTKTTEPGTETSQINLSDLKVSTLVRKPQPDFRNDGFSPKFNTSSSISSENSIIKGGAKNQALLHSKSKQPKIRSIKCKHKENPVVAEPPVANEDCSLKCCSSDNKGSPLASISKSGKVDGLKLLSNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKPSKPLLFSSASGQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRIMTAQNLVSYRSPGLGDCSTSSPVSAPKVLVSGGSNHSSEKSGDGTQDPVHPGPGGGDSALSGELSTSLPGLGSDKRDLPASGKNRSNCVTRRNCGRSKPSKFRDGFSAQMGKNTVNRKALKTERRRKLNELPAVTLEAALQGDRESRGSEKSSSRGEAEDPGKEPTLQLMGHLTSEDGAHFSSVSFDNKVNQSDPEKIPEKGPSFEIRKVPELDSEMNSENDEPSSINEAVPKKRWQRLNQRRTKPRKRTNRFKEKENSEGAFGVLLSADPVKKEDEFPEQRPPASTNKLEDALTDPNHANHLDSAGPRLNVCDKSNASNEEMEKEPGIPSLTPQPELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKTQEQVHKVSSRCEEESLLARCRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKPPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLTKKCYEAGHLENDINESCAAPRSKEFGGGTTKLFDKPRKRKRQRHATAKLHCKKVKNDISSKETPNSEGELMTHRTAASPKETVEEGVENDHGMPASKKLQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICTTCHAANPASVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFTKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRTQGEVTKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPPGPSTHLAEQSSGVAAQGPKMSDKPSADTNPSLSLSKKALAGTCQRPPLPERPPDRTDSRPQPVDRVRDLAGSGTKPQSLVSSQKPLDRPPAVAGPRPQLSDKPSPVTGPSSSPSVRSQPLERPLGTADPRLDKSIGAASPRPQSLEKTPVPTGLRLPPPEKLLVTSGPKPQTSDRPPDKSHVSLSQRLPPPDKVLSAVVQTLVAKEKALRPVDQNTQSKNRAALVMDLIDLTPRQKDRAGSPHELTPQADEKMPVLESSSWPASKGLGQIPRAVERGSVSDAVLQPLGKAAATSEHSWQAVKSLTQARLLSQPPAKAFLYEPATQASGRAPAGAEQTPGPPSQAPGLVKQVKQMAGGQQLPGLAAKSGQSFRPLGKSSLSTEEKKLAPTEQSPWALGKASPGPGLWPMVAGQTLAQSCWSSGSTQTLAQTCWSLGRGKDPKPEQSTLPALNQAPSSHKCAESEQK", "length": 2698, "header": "tr|E1BM66-1|E1BM66_BOVIN Isoform 1 of Histone-lysine N-methyltransferase, H3 lysine-36 specific OS=Bos taurus OX=9913 GN=NSD1 PE=4 SV=2 CANONICAL=E1BM66-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S1J5-1", "url": "https://www.uniprot.org/uniprotkb/E1BM66/entry#A0AAA9S1J5-1", "sequence": { "sequence": "MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTASGTSQNAYGQDSPSCYIPLRKLQDLASMINVEYLNGSADGSESFQDPEKSDSRAQSPVVCTSLNPGGPTALAMKQEPSCNNSPELQVKVTKTVKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYEPKSENGVDVAMGDEQDSTPDSRHGAGKPPFLPLAPQTETQRNKQRSDVDGSHEKAALLPAPLSLGDTNVTIEEQLNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFVPQKILSKWEASVGLAEQYDIPKGSKNRKCVTSSIKLDSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHMQFETHKEERRGKIPENLGLNFISGDVSDKQASNELSRIANSLTGPSTAPGSFLFSSCAKNTAKKEFETSNCDSLLGLSEGALISKRSGEKKKFQRGLMCSSKVQLCYIGAGDEEKRSDSISICTTSDDGSSDLDPVDHSSESDNSVLEITDAFDRSENLLPVQKNEKVKYSRYPATNTKVKAKQKSLITNSHTDHLINCTKTTEPGTETSQINLSDLKVSTLVRKPQPDFRNDGFSPKFNTSSSISSENSIIKGGAKNQALLHSKSKQPKIRSIKCKHKENPVVAEPPVANEDCSLKCCSSDNKGSPLASISKSGKVDGLKLLSNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKPSKPLLFSSASGQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRIMTAQNLVSYRSPGLGDCSTSSPVSAPKVLVSGGSNHSSEKSGDGTQDPVHPGPGGGDSALSGELSTSLPGLGSDKRDLPASGKNRSNCVTRRNCGRSKPSKFRDGFSAQMGKNTVNRKALKTERRRKLNELPAVTLEAALQGDRESRGSEKSSSRGEAEDPGKEPTLQLMGHLTSEDGAHFSSVSFDNKVNQSDPEKIPEKGPSFEIRKVPELDSEMNSENDEPSSINEAVPKKRWQRLNQRRTKPRKRTNRFKEKENSEGAFGVLLSADPVKKEDEFPEQRPPASTNKLEDALTDPNHANHLDSAGPRLNVCDKSNASNEEMEKEPGIPSLTPQPELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKTQEQVHKVSSRCEEESLLARCRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKPPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLTKKCYEAGHLENDINESCAAPRSKEFGGGTTKLFDKPRKRKRQRHATAKLHCKKVKNDISSKETPNSEGELMTHRTAASPKETVEEGVENDHGMPASKKLQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICTTCHAANPASVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFTKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRTQGEVTKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPPGPSTHLAEQSSGVAAQGPKMSDKPSADTNPSLSLSKKALAGTCQRPPLPERPPDRTDSRPQPVDRVRDLAGSGTKPQSLVSSQKPLDRPPAVAGPRPQLSDKPSPVTGPSSSPSVRSQPLERPLGTADPRLDKSIGAASPRPQSLEKTPVPTGLRLPPPEKLLVTSGPKPQTSDRPPDKSHVSLSQRLPPPDKVLSAVVQTLVAKEKALRPVDQNTQSKNRAALVMDLIDLTPRQKDRAGSPHELTPQADEKMPVLESSSWPASKGLGQIPRAVERGSVSDAVLQPLGKAAATSEHSWQAVKSLTQARLLSQPPAKAFLYEPATQASGRAPAGAEQTPGPPSQAPGLVKQVKQMAGGQQLPGLAAKSGQSFRPLGKSSLSTEEKKLAPTEQSPWALGKASPGPGLWPMVAGQTLAQSCWSSGSTQTLAQTCWSLGRGKDPKPEQSTLPALNQAPSSHKCAESEQK", "length": 2595, "header": "tr|A0AAA9S1J5-1|E1BM66_BOVIN Computationally mapped isoform of Histone-lysine N-methyltransferase, H3 lysine-36 specific OS=Bos taurus OX=9913 GN=NSD1 PE=4 SV=1 CANONICAL=E1BM66-1" }, "locus": { "chromosome": "7", "start_pos": 38767515, "end_pos": 38621346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104536.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104536.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077177.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077177.1" } ] } }, { "isoform_ac": "A0AAA9T8D7-1", "url": "https://www.uniprot.org/uniprotkb/E1BM66/entry#A0AAA9T8D7-1", "sequence": { "sequence": "MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTASGTSQNAYGQDSPSCYIPLRKLQDLASMINVEYLNGSADGSESFQDPEKSDSRAQSPVVCTSLNPGGPTALAMKQEPSCNNSPELQDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKATPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDIPKGSKNRKCVTSSIKLDSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHMQFETHKEERRGKIPENLGLNFISGDVSDKQASNELSRIANSLTGPSTAPGSFLFSSCAKNTAKKEFETSNCDSLLGLSEGALISKRSGEKKKFQRGLMCSSKVQLCYIGAGDEEKRSDSISICTTSDDGSSDLDPVDHSSESDNSVLEITDAFDRSENLLPVQKNEKVKYSRYPATNTKVKAKQKSLITNSHTDHLINCTKTTEPGTETSQINLSDLKVSTLVRKPQPDFRNDGFSPKFNTSSSISSENSIIKGGAKNQALLHSKSKQPKIRSIKCKHKENPVVAEPPVANEDCSLKCCSSDNKGSPLASISKSGKVDGLKLLSNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKPSKPLLFSSASGQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRIMTAQNLVSYRSPGLGDCSTSSPVSAPKVLVSGGSNHSSEKSGDGTQDPVHPGPGGGDSALSGELSTSLPGLGSDKRDLPASGKNRSNCVTRRNCGRSKPSKFRDGFSAQMGKNTVNRKALKTERRRKLNELPAVTLEAALQGDRESRGSEKSSSRGEAEDPGKEPTLQLMGHLTSEDGAHFSSVSFDNKVNQSDPEKIPEKGPSFEIRKVPELDSEMNSENDEPSSINEAVPKKRWQRLNQRRTKPRKRTNRFKEKENSEGAFGVLLSADPVKKEDEFPEQRPPASTNKLEDALTDPNHANHLDSAGPRLNVCDKSNASNEEMEKEPGIPSLTPQPELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKTQEQVHKVSSRCEEESLLARCRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKPPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLTKKCYEAGHLENDINESCAAPRSKEFGGGTTKLFDKPRKRKRQRHATAKLHCKKVKNDISSKETPNSEGELMTHRTAASPKETVEEGVENDHGMPASKKLQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICTTCHAANPASVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFTKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRTQGEVTKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPPGPSTHLAEQSSGVAAQGPKMSDKPSADTNPSLSLSKKALAGTCQRPPLPERPPDRTDSRPQPVDRVRDLAGSGTKPQSLVSSQKPLDRPPAVAGPRPQLSDKPSPVTGPSSSPSVRSQPLERPLGTADPRLDKSIGAASPRPQSLEKTPVPTGLRLPPPEKLLVTSGPKPQTSDRPPDKSHVSLSQRLPPPDKVLSAVVQTLVAKEKALRPVDQNTQSKNRAALVMDLIDLTPRQKDRAGSPHELTPQADEKMPVLESSSWPASKGLGQIPRAVERGSVSDAVLQPLGKAAATSEHSWQAVKSLTQARLLSQPPAKAFLYEPATQASGRAPAGAEQTPGPPSQAPGLVKQVKQMAGGQQLPGLAAKSGQSFRPLGKSSLSTEEKKLAPTEQSPWALGKASPGPGLWPMVAGQTLAQSCWSSGSTQTLAQTCWSLGRGKDPKPEQSTLPALNQAPSSHKCAESEQK", "length": 2558, "header": "tr|A0AAA9T8D7-1|E1BM66_BOVIN Computationally mapped isoform of Histone-lysine N-methyltransferase, H3 lysine-36 specific OS=Bos taurus OX=9913 GN=NSD1 PE=4 SV=1 CANONICAL=E1BM66-1" }, "locus": { "chromosome": "7", "start_pos": 38767515, "end_pos": 38621346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116082.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116082.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093073.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093073.1" } ] } }, { "isoform_ac": "E1BM66-1", "url": "https://www.uniprot.org/uniprotkb/E1BM66/entry#E1BM66-1", "sequence": { "sequence": "MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTASGTSQNAYGQDSPSCYIPLRKLQDLASMINVEYLNGSADGSESFQDPEKSDSRAQSPVVCTSLNPGGPTALAMKQEPSCNNSPELQVKVTKTVKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYEPKSENGVDVAMGDEQDSTPDSRHGAGKPPFLPLAPQTETQRNKQRSDVDGSHEKAALLPAPLSLGDTNVTIEEQLNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKATPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDIPKGSKNRKCVTSSIKLDSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHMQFETHKEERRGKIPENLGLNFISGDVSDKQASNELSRIANSLTGPSTAPGSFLFSSCAKNTAKKEFETSNCDSLLGLSEGALISKRSGEKKKFQRGLMCSSKVQLCYIGAGDEEKRSDSISICTTSDDGSSDLDPVDHSSESDNSVLEITDAFDRSENLLPVQKNEKVKYSRYPATNTKVKAKQKSLITNSHTDHLINCTKTTEPGTETSQINLSDLKVSTLVRKPQPDFRNDGFSPKFNTSSSISSENSIIKGGAKNQALLHSKSKQPKIRSIKCKHKENPVVAEPPVANEDCSLKCCSSDNKGSPLASISKSGKVDGLKLLSNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKPSKPLLFSSASGQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRIMTAQNLVSYRSPGLGDCSTSSPVSAPKVLVSGGSNHSSEKSGDGTQDPVHPGPGGGDSALSGELSTSLPGLGSDKRDLPASGKNRSNCVTRRNCGRSKPSKFRDGFSAQMGKNTVNRKALKTERRRKLNELPAVTLEAALQGDRESRGSEKSSSRGEAEDPGKEPTLQLMGHLTSEDGAHFSSVSFDNKVNQSDPEKIPEKGPSFEIRKVPELDSEMNSENDEPSSINEAVPKKRWQRLNQRRTKPRKRTNRFKEKENSEGAFGVLLSADPVKKEDEFPEQRPPASTNKLEDALTDPNHANHLDSAGPRLNVCDKSNASNEEMEKEPGIPSLTPQPELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKTQEQVHKVSSRCEEESLLARCRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKPPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLTKKCYEAGHLENDINESCAAPRSKEFGGGTTKLFDKPRKRKRQRHATAKLHCKKVKNDISSKETPNSEGELMTHRTAASPKETVEEGVENDHGMPASKKLQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICTTCHAANPASVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFTKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRTQGEVTKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPPGPSTHLAEQSSGVAAQGPKMSDKPSADTNPSLSLSKKALAGTCQRPPLPERPPDRTDSRPQPVDRVRDLAGSGTKPQSLVSSQKPLDRPPAVAGPRPQLSDKPSPVTGPSSSPSVRSQPLERPLGTADPRLDKSIGAASPRPQSLEKTPVPTGLRLPPPEKLLVTSGPKPQTSDRPPDKSHVSLSQRLPPPDKVLSAVVQTLVAKEKALRPVDQNTQSKNRAALVMDLIDLTPRQKDRAGSPHELTPQADEKMPVLESSSWPASKGLGQIPRAVERGSVSDAVLQPLGKAAATSEHSWQAVKSLTQARLLSQPPAKAFLYEPATQASGRAPAGAEQTPGPPSQAPGLVKQVKQMAGGQQLPGLAAKSGQSFRPLGKSSLSTEEKKLAPTEQSPWALGKASPGPGLWPMVAGQTLAQSCWSSGSTQTLAQTCWSLGRGKDPKPEQSTLPALNQAPSSHKCAESEQK", "length": 2698, "header": "tr|E1BM66-1|E1BM66_BOVIN Isoform 1 of Histone-lysine N-methyltransferase, H3 lysine-36 specific OS=Bos taurus OX=9913 GN=NSD1 PE=4 SV=2 CANONICAL=E1BM66-1" }, "locus": { "chromosome": "7", "start_pos": 38767515, "end_pos": 38621346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034204.7", "url": "https://www.ensembl.org/id/ENSBTAT00000034204.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034104.4", "url": "https://www.ensembl.org/id/ENSBTAP00000034104.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-3214841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214841", "resource": "Reactome", "description": "PKMTs methylate histone lysines" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AA00-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTCELSRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTASGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSADGSESFQDPEKSDSRAQSPVVCTSLSPGGPTALAMKQEPSCNNSPELQVKVTKTVKNGFLHFENFTCVDDADIDSEMDPEQPVTEDESIEEIFEETQTNATCNYEPKSENGVDVAMGNEQDSTPESRHGAVKPPFLALAPQTETQKNKQRNEVDGSNEKASLLPAPFSLGDAKVTIEEQLNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKATPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKESKNRKCITSSIKLDSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCVKSRARKSSDNPKRTSVKKGHMQFEAHKEERRGKIPENLGLNFISGDVSDKQASNELSRIANSLTGSSTAPGSFLFSSCAKNTAKKEFETSNCDSLLGLSEGALISKRSGEKKKLQQSLVCSSKVQLCYIGAGDEEKRSDSISICTTSDDGSSDLDPIDHSSESDNSVLEITDTFDRTENMLPVQKNEKVKYSRYPATNTKVKAKQKTLITNSHTDHLTDCTKIAEPGTETSQVNIADLKVSTLVRKPQSDFRNDGLSPKFNTPSSISGDNSLIKGGATNQALLHSKSKQPKIRSIKCKHKENPVVGEPPVANEDCSLKCCSSDTKGSPLASISKSGKMDGLKLLSNMHEKTRDSNDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKPSKPLLFSSASGQNHMPIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGLGDCSTSSPVGASKVLVSGGSTYNSEKNGDSTQDPVRPSPTGGDSTLSGELSGSPPGLVSGKRDLPASGKSRSNCVTRRNCGRSKPSKLRDGFSAQVGRNTVNRKALKTERKRKLNRLPAVTLEAALQRERESRGSENGSSRGEAESPGKEEPLPLKGHLTSEDGAHFSSVSFDNKVNHSDPGKIPEKGPSFENVKGPELDSEMNSENDELNCVNQAVPKKRWQRLNQRRIKPRKRTNRFREKENSEGAFGVLLPADPVKKGDALPDQRPPPPPANILEDALTDPSHADCLDSAEPRLNVCDKSSASIEEMEKEPGIPSLTPQPELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARCRSSAQNKQVEENSLISTKEEPPVLEREAPFLEGPLAQSEVGGGHAELPQLTLSVPVALEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLPKKCYEAGHLENDITESCATSRSKEFAGGATKLFDKPRKRKRQRHATVKMHCKKVKNDSSSKEPPSSEGELMAHRTAASPKETIEEGVENDHGMPASKKLQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICITCHAANPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFTKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRTQGEVTKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPPGPSTHLAEPSSGVAAQGPKMSDKPSADTNQTLSLSKKALAGTCQRPPLPERPPDRTDSRPQPVDRVRDLAGSGTKSQSLVSSQKPLDRPPALAGPRSQLSDKPSPVTSPSSSPSVRSQPLERPLGTADPRLDKSIGAASPRPQSLEKTPVPTGLRLPPPDRLLVTSGPKPQSSDRPPDKSHASLSQRLPPPDKVLSAVVQTLVAKEKALRPVDQNTQSKNRAALVMDLIDLTPRQKERAASPHDIIPQADEKMPVLESTSWPASKCLGQMPRAVERSSVSDPVLLPPSKAAAPPEHPWQAVKSLTQARLLSQPPAKAFLYEPTTQASGRAPAGAEQTTGPPSQAPGLVKQVKQLVGGQQLPGLAAKSGQSFRPLGKTPSSLSTEEKKLTTTEQNPWALGKASPGPGLWPMVAGQTLAQSCWSSGSTQTLAQTCWSLGRGQDPKPEQNTLPALNQAPSSHKCAESEQK", "length": 2701 }, "evidence": [ { "id": "E1BM66", "url": "https://omabrowser.org/oma/group/E1BM66/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AMN8-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "Nsd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQSCELSRRNCLLSFSNSVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLPTASGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLSGSADGSESFQDPAKSDSRAQSPIVCTSLSPGGPTALAMNQEPTCNNPPELQLSVTKTTKNGFLHFDNFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNASCNYEPKSENGVEMAMGSEQDSMPESRHGAVEQPFVPLAPQTEKQKNKQRSEVDGSNEKTALLPAPNSLGDTNVTIEEQFNSINLSFQDDPDSSTSTLGNMLELPGTSSPSTSQELPFCHPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVANRRPYREYYVEAFGDPSEKAWVAGKAIVMFEGRHQFEELPVLRKRGKQKEKGYRHKVPQKILSKWEASVGLAEQCDVPRGPKTQKCVPSSAKLDSEEDMPFEDCANDPDSEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRVRKSSDNIKRTSVKKGLMPFEAQKEERRGKSPENLGLDFLSGGVSDKQASNELSRIANSLTGSSAAPGQFLFSSCGQNTAKTDFETPNCDSLSGLSESALISKHSGEKKKLQPGQVCSSKVQLCYVGAGDEEKRSDSVSVCTTSDDGSSDLDPTEHNSEFHKSVLEVTDALDKTENALSMHKNETKYSRYPATNRVKEKQKSLITNSHTDHLMDSTKTVEPGTAEISQVNLSDLKISSPIPKPQPEFRNDGLTTKFNAPPGIRNENSLTKGGLANQTLLPLKCRQPKFRSIKCKHKESPTAAETSATSEDLSLKCCSSDTNGSPMTSISKSGKGEGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKSSKPLLFSSASSQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNVASYRTPDRGDCSSGSPVGTSKVLVLGGSTHNSEKPGDSTQDSVRLSPGGGDSALSGELSSSLSVLPSDKRDLPACGKIRSNCIPRRNCGRAKLSPKLRVTISTQMAKPSVNPKALKTERKRKLSRLPAVTLAANGLGNKESGGSVNGPLKGGAQDPAKEEPLQQMDLLRNEETHFDSKVKQSDPDKILEKEPSFENRKGPEVGSEINIENDEPHGVDQVVPKKRWQRLNQRRPKPGKRASRFREKENSEGAFGVLLPGDPVQKGRDDYLEQRAPPTSILEDSAADPNHVSHSESVGPRLNVCDKSSVSMGDLEKETGIPSLTPQTKIPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEDESLLARCRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLVQSDLGVAHAELPQLTLSVPVAPEVSPRPTLESEELLVKTPGNYEGKRQRKPTKKLLESNDLDPGFMPKKGDLGLSRKCCESGHLENGVGDSRATPHLKEFGGGTTRIFDKPRKRKRQRHGTARVHYKRVKKEDSARETPSSAEGELMIHRTAASPKEILEEGIEHDPGMSASKRLQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVVQNKGFRCPLHICITCHAANPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPDVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIVTEEKSRKFKRKPHGKRRSQGEVTKEREDECFSCGDGGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDVCGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPTATLSPSPGTQQTEQSSEMGTQGPKKSDQPPTDATQMLSLSKKAVTGTCQRPLLPERPPERTDSSSHLLDRIRDLAGSGTKSQSLVSSQRPQDRPPAKEGPRPQPPDRASPVTRPSSSPSVSSLPLERPLRMTEPRLDKSIGAASPKSQAVEKPPAPTGLRLSSPDRLLNTNSPKPQISDRPPDKSHASLTQRLPPPEKVLSAVVQSLVAKEKALRPVDQNTQAKHRAAVVMDLIDLTPRQKERAASPQEVTAQADEKTPVLESSSRPTSRGLGHVPRAVEKGGVSDPLQPPGKSAAPSEHPWQAVKSLTHARFLSPPSAKAFLYESAIQASGRAPVGSEQTPGPPSPAPGLLKQVKQLSRGLTAKSGQSFRSLGKISASLPNEEKKLTTTEQSPWGLGKASPGAGLWPIVAGQTLAQACWSSGGTQTLAQNCWSLGRGQDPKPEQNAIQALNQAPSSRKCAESEQK", "length": 2689 }, "evidence": [ { "id": "E1BM66", "url": "https://omabrowser.org/oma/group/E1BM66/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0Y2K5-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQACEVSRRSCLVPFGTSLPAAEPKGGPFGEPRGPEPPAMQLAAAKPGFGQDPSSCYIPLRRLQDLASMISAEYLGGPADGAEALPDPGSPPPRAPAPQEPPGGAGPEPAALGFPLLLRDGGDDEEEEEEEEEEDDDDDEEDDDDDDDEEPEHSRGAGSPEPPRLQPAELPGSDGGPGEDAEPSGSAAAALQLIRAKKKPTPVKYEVGDLVWAKFNRRPWWPCTICHDAVLDCHSKMKVSNRRPYREYYVDPLGEPSEKAWVAGKAIVLFEGRHQFEELPVLRRRGKQKEKGYKHKVPQRFMAKWEVSVGQAEDMLLGGPEDQKCSQNSSELDSEKEVQSEYYSNGPGAKKDRQLNGCFKSLAFDSKHSANEKGKSHIKPHMKKSSESRKRTRVKKSGMREEASKGEIQEETPESIVNNMIVGDLPEKHASHELRRIAKSITASNSTRENHLLSSFGERRFENITLKSDYGSHKSDALKNTLQGDLFSNASLEREKSSLGILCSSKLQIHYSASEAGVEKKQTESDSSSSLSDGGNSDVDTMDQSSERASSTLEVSDSSDKMEKEFPMTSSGNIKLSMYFSQKSSRRARKKSYRDRKPLGGLVTSRLDAEFAHRELEGGSSDAEMSLTALECSSDVRNDNLSLANKHATPQSVSKDSSWSAVANQTTLKLKNMKLPRIRSIKCKHKEKVAGLEPSLAEEESGMNHCSSDTKGFSGLQRDSLQRSGKADGQKLLNNVHEKPRDSAEIETAVVKHVLSELKELSYRSMNDDVGDSGTPKATVPLLFSSASGHGRLPIEPNYRFSTLLMMLKDIHDSKAKEQQLMTGQNIVPYRNTGTADGSGGNSASSLTSLSIVGPPFKIEKNGDCAQETVSPNSSSISNSSFSRNPPAKLPGSGTGKREPANAAVSGTNGTNCVPKRNCSKSKQSTKLGDKTVSNRKDLKPGGPSKFLSRLSRDSGEHAFRVHGSVASPLGNEAEDTERKESVDLTEHSTDEDSACLSDDNLGRIGRRPEAGRNTERCASAENGESPDLDSEANSESSLGDEANDVNHVAPKKRWQRFNQSSARSNKHISRSREKGNLESAFGLNSHGFSLKGNECLGRRHSPHSKVLEADLTVQDYENHLDLVEKRLNVCGKPNNSVMDSETKLGNFAPQSEFSAQVHSERKRLRKPSKRLLEYAEEYDHLFAPKKKSRKSQEQLRKVNSVARSGFEGGLPAQRSPDRETQRGPSPLVSTPFSTKESPPILEAECSFSELEPHASDPSEQLIEGQSDFPELVLSSSDVSEVSASPDAEERFLKSGNFESKRQRKPTKKLLESNDLDTAFMPKKEEWTPPKKGTGPSESDSLELYSPAHFPDLGEASEKLLEKQRKRKRPRHSSAAVHSKKEKNGERLGETPRSEGETLVHGTSTSPKGGHEDGSENDHGVPSSKKIQGERGGGAALKENVCQICEKPGELLLCEAQCCGAFHLQCLGLSEMPTGKFICNECSTGVHTCFVCKNCGQDVKRCLLPLCGKYYHEECIQKYPPTVTQNKGFRCSLHICMTCHAANPTNISASKGRLMRCVRCPVAYHSNDFCLAAGSVVLASNSIICPNHFTARRGCRNHEHVNVSWCFVCSEGGSLLCCESCPAAFHRECLNIEMPEGSWYCNDCKAGKKPHYKEVVWVKVGRYRWWPAEICHPRTIPVNIQKMKHDIGEFPVLFFGSKDYLWTHQARVFPYMEGDVSSKDKMGKGVDGIYKKALHEAAVRFEELKAQKELRQLQEDKKNDKKPPPYKHIKVNRPVGKVQIFTADLSEIPRCNCKPTDENPCGLDSECINRMLLYECHPLVCPAGERCQNQCFSKRQYPEVQIFRTLARGWGLQAKTDIRKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWCVNGDTRVGLFAIVNIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKSQPTLSEEKSKKLKRRPQMKRRSQAEVMKEREDECFSCGDGGQLVSCKKAGCPKVYHADCLNLTKRPAGKWECPWHQCDMCGKEAASFCEMCPRSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPMGALTNGDDTQPPEQPPADTDPSIQPLDRLPQSVAFKLQSPEKPPATLALRLPPSEKPPTTLALRVQPSNKPPTTLALRLPPPDKPPAALALRLPPSNKPPTTLSLRLKPSNKPPTTLSLRLQPSDKPPTTLSLRLQPSDRPQAALSLRLQPEKQPVILALKPQQPDKPPTNAVLWPLDESSGDASEPHLPSKSPPGTPHSLDGSLVPAGALLQLSDEPPAIAEVLELSDKSLIDTETQEIELLDEFPAKCLHPQLSDRLLATAGTLQSQPVDEPPVAEQPQLLSKASAQSPQPQPAEKSPSSAIPHIPASEEILSPDVEVLWPLPIENVPTSPVSRILPMEKAPGLGVLRLPPPEKASFSGAVRVSAVEKAPSSGALHAFAPEKAPASGMPRILPSDKGPSLGVSWPLSLEKAHGSRSPHILPTDKALGSGALRIPLMQKVLSPGVLRPLPLEKAADAGALRPLPLEKALGSGVARPQLLERPPSLTATWPQASDKLAAAVAPRPQALDKPPAASAPRLLLSEKALRPVDQNAQPKERGAPAAELSPQQKERTMLAGEQISWSAGKAVAHVGQVPWPTEKLQTHEQSHWPTAKALTPAEQSPRTAEKLPEPTLQPSWEVASVPAEQTPWTSERLRVFEQTPRPAREAPVPQEQTQWIVTNIQTIEQISWLSGKVHIPRGQDPLPEQNTALAHNQDSVCHELADSEPK", "length": 2829 }, "evidence": [ { "id": "E1BM66", "url": "https://omabrowser.org/oma/group/E1BM66/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O88491-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "Nsd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRTCELSRRNCLLSFSNPVNLDASEDKDSPFGNGQSNFSEPLNGCTMQLPTAASGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLSGSADGSESFQDPAKSDSRAQSPIVCTSLSPGGPTALAMKQEPTCNNSPELQLRVTKTTKNGFLHFENFTGVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYEPKSENGVEVAMGSEQDSMPESRHGAVERPFLPLAPQTEKQKNKQRSEVDGSNEKTALLPAPTSLGDTNVTVEEQFNSINLSFQDDPDSSPSPLGNMLEIPGTSSPSTSQELPFVPQKILSKWEASVGLAEQYDVPKGSKNQKCVSSSVKLDSEEDMPFEDCTNDPDSEHLLLNGCLKSLAFDSEHSADEKEKPCAKSRVRKSSDNIKRTSVKKDLVPFESRKEERRGKIPDNLGLDFISGGVSDKQASNELSRIANSLTGSSTAPGSFLFSSSVQNTAKTDFETPDCDSLSGLSESALISKHSGEKKKLHPGQVCSSKVQLCYVGAGDEEKRSNSVSVSTTSDDGCSDLDPTEHNSGFQNSVLGITDAFDKTENALSVHKNETQYSRYPVTNRIKEKQKSLITNSHADHLMGSTKTMEPETAELSQVNLSDLKISSPIPKPQPEFRNDGLTTKFSAPPGIRNENPLTKGGLANQTLLPLKCRQPKFRSIKCKHKESPAVAETSATSEDLSLKCCSSDTNGSPLANISKSGKGEGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTAKASKPLLFSSASSQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLASYRTPDRGDCSSGSPVGTSKVLVLGSSTPNSEKPGDSTQDSVHQSPGGGDSALSGELSSSLSSLASDKRELPACGKIRSNCIPRRNCGRAKPSSKLRETISAQMVKPSVNPKALKTERKRKFSRLPAVTLAANRLGNKESGSVNGPSRGGAEDPGKEEPLQQMDLLRNEDTHFSDVHFDSKAKQSDPDKNLEKEPSFENRKGPELGSEMNTENDELHGVNQVVPKKRWQRLNQRRPKPGKRANRFREKENSEGAFGVLLPADAVQKAREDYLEQRAPPTSKPEDSAADPNHGSHSESVAPRLNVCEKSSVGMGDVEKETGIPSLMPQTKLPEPAIRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEDESLLARCQPSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSDLGVTHAELPQLTLSVPVAPEASPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSRKCFEASRSGNGIVESRATSHLKEFSGGTTKIFDKPRKRKRQRLVTARVHYKKVKKEDLTKDTPSSEGELLIHRTAASPKEILEEGVEHDPGMSASKKLQVERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLPEMPRGKFICNECHTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVTQNKGFRCPLHICITCHAANPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKARKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGVRCQNQCFSKRQYPDVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIVTEEKSRKFKRKPHGKRRSQGEVTKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDVCGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPTATSPPSPGTQPKEQSSEMATQGPKKSDQPPTDATQLLPLSKKALTGSCQRPLLPERPPERTDSSSHLLDRIRDLAGSGTKSQSLVSSQRPQDRPPAKEGPRPQPPDRASPMTRPSSSPSVSSLPLERPLRMTDSRLDKSIGAASPKSQAVEKTPASTGLRLSSPDRLLTTNSPKPQISDRPPEKSHASLTQRLPPPEKVLSAVVQSLVAKEKALRPVDQNTQSKHRPAVVMDLIDLTPRQKERAASPQEVTPQADEKTAMLESSSWPSSKGLGHIPRATEKISVSESLQPSGKVAAPSEHPWQAVKSLTHARFLSPPSAKAFLYESATQASGRTPVGAEQTPGPPSPAPGLVKQVKQLSRGLTAKSGQSFRSLGKISASLPNEEKKLTTTEQSPWGLGKASPGAGLWPIVAGQTLAQACWSAGGTQTLAQTCWSLGRGQDPKPENAIQALNQAPSSRKCADSEKK", "length": 2588 }, "evidence": [ { "id": "E1BM66", "url": "https://omabrowser.org/oma/group/E1BM66/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVSGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNSPELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTETQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQLNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLDSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFISGDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAKKEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDEEKRSDSISICTTSDDGSSDLDPIEHSSESDNSVLEIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAEPGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFNLSSSISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEECSLKCCSSDTKGSPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSGELSASLPGLLSDKRDLPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLRGGAEDPSKEDPLQIMGHLTSEDGDHFSDVHFDSKVKQSDPGKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTKPRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKCYEAGHLENGITESCATSYSKDFGGGTTKIFDKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMPASKKMQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICITCHAANPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRTQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPPGPSTHLAEQSTGMAAQAPKMSDKPPADTNQMLSLSKKALAGTCQRPLLPERPLERTDSRPQPLDKVRDLAGSGTKSQSLVSSQRPLDRPPAVAGPRPQLSDKPSPVTSPSSSPSVRSQPLERPLGTADPRLDKSIGAASPRPQSLEKTSVPTGLRLPPPDRLLITSSPKPQTSDRPTDKPHASLSQRLPPPEKVLSAVVQTLVAKEKALRPVDQNTQSKNRAALVMDLIDLTPRQKERAASPHQVTPQADEKMPVLESSSWPASKGLGHMPRAVEKGCVSDPLQTSGKAAAPSEDPWQAVKSLTQARLLSQPPAKAFLYEPTTQASGRASAGAEQTPGPLSQSPGLVKQAKQMVGGQQLPALAAKSGQSFRSLGKAPASLPTEEKKLVTTEQSPWALGKASSRAGLWPIVAGQTLAQSCWSAGSTQTLAQTCWSLGRGQDPKPEQNTLPALNQAPSSHKCAESEQK", "length": 2696 }, "evidence": [ { "id": "E1BM66", "url": "https://omabrowser.org/oma/group/E1BM66/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "histone H3K36 dimethyltransferase activity", "id": "GO:0140954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140954", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "nuclear androgen receptor binding", "id": "GO:0050681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050681", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" }, { "name": "histone H3K36 methyltransferase activity", "id": "GO:0046975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046975", "evidence": [ { "database": "UniProtKB", "id": "E1BM66", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1011, "end_pos": 1013, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1118, "end_pos": 1120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1244, "end_pos": 1246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1449, "end_pos": 1451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1709, "end_pos": 1711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2079, "end_pos": 2081, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2151, "end_pos": 2153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 729, "end_pos": 731, "annotation": "n_glycosylation_sequon" }, { "start_pos": 756, "end_pos": 758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" }, { "start_pos": 962, "end_pos": 964, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60308", "name": "", "equation": "L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-homocysteine + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VD24-1", "F1MMY4-1", "E1BM66-1" ], "evidence": [ { "id": "60308", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60308" } ] }, { "id": "R-BTA-4827383", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P585-1", "F1MMY4-1", "E1BGA4-1", "E1BM66-1" ], "evidence": [ { "id": "R-BTA-4827383", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4827383" } ] }, { "id": "R-BTA-5638157", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P585-1", "F1MMY4-1", "E1BGA4-1", "E1BM66-1" ], "evidence": [ { "id": "R-BTA-5638157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5638157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BGA4", "gene_name": "ASH1L", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] }, { "ec_number": "2.1.1.367", "activity": "L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] }, { "ec_number": "2.1.1.367", "activity": "", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] } ] }, { "uniprot_ac": "E1BM66", "gene_name": "NSD1", "activity": [ { "ec_number": "2.1.1.357", "activity": "L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ] }, { "ec_number": "2.1.1.357", "activity": "", "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66" } ] } ] }, { "uniprot_ac": "F1MMY4", "gene_name": "NSD2", "activity": [ { "ec_number": "2.1.1.357", "activity": "L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "F1MMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMY4" } ] }, { "ec_number": "2.1.1.357", "activity": "", "evidence": [ { "id": "F1MMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMY4" } ] } ] }, { "uniprot_ac": "Q0P585", "gene_name": "SMYD2", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q0P585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P585" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "Q0P585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P585" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "Q0P585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P585" } ] } ] }, { "uniprot_ac": "Q0VD24", "gene_name": "SETMAR", "activity": [ { "ec_number": "2.1.1.357", "activity": "L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "Q0VD24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD24" } ] }, { "ec_number": "2.1.1.357", "activity": "", "evidence": [ { "id": "Q0VD24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD24" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66" }, { "id": "PS51215", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51215" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AWS", "eco_id": "ECO_0000259", "start_pos": 1893, "end_pos": 1943, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 1546, "end_pos": 1592, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66" }, { "id": "PS50812", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50812" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 323, "end_pos": 388, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66" }, { "id": "PS50868", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50868" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Post-SET", "eco_id": "ECO_0000259", "start_pos": 2069, "end_pos": 2085, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM66" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 1945, "end_pos": 2062, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.357", "ec_name": "L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "2.1.1.357", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.357" }, { "id": "2.1.1.357", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.357" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1011, "end_pos": 1013 }, { "start_pos": 1118, "end_pos": 1120 }, { "start_pos": 1244, "end_pos": 1246 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 1449, "end_pos": 1451 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 1709, "end_pos": 1711 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 2079, "end_pos": 2081 }, { "start_pos": 2151, "end_pos": 2153 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 38, "end_pos": 40 }, { "start_pos": 714, "end_pos": 716 }, { "start_pos": 729, "end_pos": 731 }, { "start_pos": 756, "end_pos": 758 }, { "start_pos": 88, "end_pos": 90 }, { "start_pos": 962, "end_pos": 964 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "exact_o_linked_glycan_sites", "count": 2 }, { "field": "exact_o_linked_glycans", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 22 }, { "field": "total_sites", "count": 22 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1452 }, { "field": "total_sites", "count": 1143 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 1389 }, { "field": "total_sites", "count": 1102 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 63 }, { "field": "total_sites", "count": 59 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 104 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1BNH5-1", "uniprot_ac": "E1BNH5", "uniprot_id": "E1BNH5_BOVIN", "mass": { "chemical_mass": 88513.0, "monoisotopic_mass": 88513.0 }, "refseq": {}, "gene_names": [ { "name": "MTMR12", "type": "recommended", "evidence": [ { "id": "E1BNH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH5" } ] } ], "protein_names": [ { "name": "Myotubularin-related protein 12", "type": "recommended", "evidence": [ { "id": "E1BNH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH5/entry#names_and_taxonomy" } ] }, { "name": "Inactive phosphatidylinositol 3-phosphatase 12", "type": "synonym", "evidence": [ { "id": "E1BNH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis.", "evidence": [ { "database": "UniProtKB", "id": "E1BNH5", "url": "https://www.uniprot.org/uniprotkb/E1BNH5#function" }, { "database": "UniProtKB", "id": "ARBA00056705", "url": "https://www.uniprot.org/uniprotkb/ARBA00056705#function" }, { "database": "UniProtKB", "id": "A0AAA9S1S6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1S6#function" }, { "database": "UniProtKB", "id": "A0AAA9SXY2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXY2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNH5", "url": "https://www.uniprot.org/uniprotkb/E1BNH5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MTMR12", "url": "https://www.uniprot.org/uniprotkb/E1BNH5", "locus": { "chromosome": "20", "start_pos": 41390441, "end_pos": 41322993, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012278", "url": "https://www.ensembl.org/id/ENSBTAG00000012278" } ] } } ], "crossref": [ { "id": "E1BNH5", "url": "https://alphafold.ebi.ac.uk/entry/E1BNH5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012278", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012278", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14594", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14594", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR010569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AFPKEQE", "url": "https://omabrowser.org/oma/group/AFPKEQE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNH5", "url": "https://www.orthodb.org/?gene=E1BNH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12578", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12578", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1660516", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1660516", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S1S6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1S6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1S6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXY2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXY2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH5", "url": "https://www.uniprot.org/uniprotkb/E1BNH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGAPAASAGGRCERPPLLPRVAATQGGGMLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEATEKEVTLHLLPGEQLLCEANTVLKCVQEDSCQRGIYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGVFDEKKKTLFGQLKKYPEKLVIHCKDLRVFHFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAARNSPATDPKKHAVMFDTLQDWCRELERTKGNMKYKAVSVNEGYKVCERLPAYFVVPAPLLEEDIEFFQGRGIPIWCWSCHNGCALLKMSALPKEQDDSMSQIQKNFSDRIYRTVHRPPYETAKTEDLSSNFLSLQEIQMAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAVEIIECLEAQNMNVLLLEDNASDLCCLVSSLAQVMMDPHCRTVFGFQSLVQKEWVMGGHCFLDRCNHLRQSDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDMNVGKESQDSQSRPLNLLTVWDWSVQFEPKAQTLLTNPLYVEKPKLEKVQRKGTHFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSEELQDGFREFYDGWHSRPPSYQGLLLPHLEGPEIKVWAQRYLRWIPEAQILGGGGVATMSKLLEMIEEVQRLQEKIEARHHSQEALQAEAASPPRTSGRLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV", "length": 776, "header": "tr|E1BNH5-1|E1BNH5_BOVIN Isoform 1 of Myotubularin-related protein 12 OS=Bos taurus OX=9913 GN=MTMR12 PE=3 SV=3 CANONICAL=E1BNH5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S1S6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH5/entry#A0AAA9S1S6-1", "sequence": { "sequence": "MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEATEKEVTLHLLPGEQLLCEANTVLKCVQEDSCQRGIYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGVFDEKKKTLFGQLKKYPEKLVIHCKDLRVFHFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAARNSPATDPKKHAVMFDTLQDWCRELERTKGNMKYKAVSVNEGYKVCERLPAYFVVPAPLLEEDIEFFQGRGIPIWCWSCHNGCALLKMSALPKEQDDSMSQIQKNFSDRIYRTVHRPPYETAKTEDLSSNFLSLQEIQMAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAVEIIECLEAQNMNVLLLEDNASDLCCLVSSLAQVMMDPHCRTVFGFQSLVQKEWVMGGHCFLDRCNHLRQSDKEEHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSEELQDGFREFYDGWHSRPPSYQGLLLPHLEGPEIKVWAQRYLRWIPEAQILGGGGVATMSKLLEMIEEVQRLQEKIEARHHSQEALQAEAASPPRTSGRLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV", "length": 637, "header": "tr|A0AAA9S1S6-1|E1BNH5_BOVIN Computationally mapped isoform of Myotubularin-related protein 12 OS=Bos taurus OX=9913 GN=MTMR12 PE=3 SV=1 CANONICAL=E1BNH5-1" }, "locus": { "chromosome": "20", "start_pos": 41389437, "end_pos": 41323159, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090185.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090185.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077260.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077260.1" } ] } }, { "isoform_ac": "A0AAA9SXY2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH5/entry#A0AAA9SXY2-1", "sequence": { "sequence": "MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEATEKEVTLHLLPGEQLLCEANTVLKCVQEDSCQRGIYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGVFDEKKKTLFGQLKKYPEKLVIHCKDLRVFHFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAARNSPATDPKKHAVMFDTLQDWCRELERTKGNMKYKAVSVNEGYKVCERLPAYFVVPAPLLEEDIEFFQGRGIPIWCWSCHNGCALLKMSALPKEQDDSMSQIQKNFSDRIYRTVHRPPYETAKTEDLSSNFLSLQEIQMAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAVEIIECLEAQNMNVLLLEDNASDLCCLVSSLAQVMMDPHCRTVFGFQSLVQKEWVMGGHCFLDRCNHLRQSDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDMNVHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSEELQDGFREFYDGWHSRPPSYQGLLLPHLEGPEIKVWAQRYLRWIPEAQILGGGGVATMSKLLEMIEEVQRLQEKIEARHHSQEALQAEAASPPRTSGRLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV", "length": 693, "header": "tr|A0AAA9SXY2-1|E1BNH5_BOVIN Computationally mapped isoform of Myotubularin-related protein 12 OS=Bos taurus OX=9913 GN=MTMR12 PE=3 SV=1 CANONICAL=E1BNH5-1" }, "locus": { "chromosome": "20", "start_pos": 41389437, "end_pos": 41323159, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108085.2", "url": "https://www.ensembl.org/id/ENSBTAT00000108085.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091330.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091330.1" } ] } }, { "isoform_ac": "E1BNH5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH5/entry#E1BNH5-1", "sequence": { "sequence": "MGGAPAASAGGRCERPPLLPRVAATQGGGMLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEATEKEVTLHLLPGEQLLCEANTVLKCVQEDSCQRGIYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGVFDEKKKTLFGQLKKYPEKLVIHCKDLRVFHFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAARNSPATDPKKHAVMFDTLQDWCRELERTKGNMKYKAVSVNEGYKVCERLPAYFVVPAPLLEEDIEFFQGRGIPIWCWSCHNGCALLKMSALPKEQDDSMSQIQKNFSDRIYRTVHRPPYETAKTEDLSSNFLSLQEIQMAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAVEIIECLEAQNMNVLLLEDNASDLCCLVSSLAQVMMDPHCRTVFGFQSLVQKEWVMGGHCFLDRCNHLRQSDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDMNVGKESQDSQSRPLNLLTVWDWSVQFEPKAQTLLTNPLYVEKPKLEKVQRKGTHFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSEELQDGFREFYDGWHSRPPSYQGLLLPHLEGPEIKVWAQRYLRWIPEAQILGGGGVATMSKLLEMIEEVQRLQEKIEARHHSQEALQAEAASPPRTSGRLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV", "length": 776, "header": "tr|E1BNH5-1|E1BNH5_BOVIN Isoform 1 of Myotubularin-related protein 12 OS=Bos taurus OX=9913 GN=MTMR12 PE=3 SV=3 CANONICAL=E1BNH5-1" }, "locus": { "chromosome": "20", "start_pos": 41389437, "end_pos": 41323072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000060955.5", "url": "https://www.ensembl.org/id/ENSBTAT00000060955.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053528.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053528.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 751, "start_aa": "Thr", "end_pos": 751, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr751", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-1660516", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1660516", "resource": "Reactome", "description": "Synthesis of PIPs at the early endosome membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "E1BNH5", "url": "https://www.uniprot.org/uniprotkb/E1BNH5" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "E1BNH5", "url": "https://www.uniprot.org/uniprotkb/E1BNH5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BNH5", "url": "https://www.uniprot.org/uniprotkb/E1BNH5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BNH5", "url": "https://www.uniprot.org/uniprotkb/E1BNH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNH5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 776, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNH5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNH5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH5" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 672, "start_aa": "Phe", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 751 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 324, "end_pos": 326 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 629, "end_pos": 631 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM19-1", "uniprot_ac": "E1BM19", "uniprot_id": "E1BM19_BOVIN", "mass": { "chemical_mass": 70781.0, "monoisotopic_mass": 70781.0 }, "refseq": {}, "gene_names": [ { "name": "CDKL3", "type": "recommended", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ], "protein_names": [ { "name": "Cyclin-dependent kinase-like 3", "type": "recommended", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.22", "type": "synonym", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM19", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CDKL3", "url": "https://www.uniprot.org/uniprotkb/E1BM19", "locus": { "chromosome": "7", "start_pos": 45907184, "end_pos": 45942265, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010979", "url": "https://www.ensembl.org/id/ENSBTAG00000010979" } ] } } ], "crossref": [ { "id": "E1BM19", "url": "https://alphafold.ebi.ac.uk/entry/E1BM19", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010979", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010979", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07846", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07846", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BM19", "url": "https://www.orthodb.org/?gene=E1BM19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S5Y0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4I6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4I6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4I6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM19", "url": "https://www.uniprot.org/uniprotkb/E1BM19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM19-1", "url": "https://www.uniprot.org/uniprotkb/E1BM19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQKKPGFKMEMYETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIKFLKQFRHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLPQVQHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFIEKFIPELKAKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSVWGKELEKEKRPKEIKVRVTKVKGGKGDILEPKKIVCEGGHCQQVAAEIAHTMSQDTKPVISEPPNPVNPSTNAIGMKDDPCAGGGMVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQVISNRHEDTGSTQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQSKEMKGMEVKQIKVLKRESKRTDSSKIPTLLNADQYQEKQEDGDGHCKGKNLKRNRLFFWFLRRQVRWSGTFISFTNYP", "length": 618, "header": "tr|E1BM19-1|E1BM19_BOVIN Isoform 1 of Cyclin-dependent kinase-like 3 OS=Bos taurus OX=9913 GN=CDKL3 PE=3 SV=3 CANONICAL=E1BM19-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S5Y0-1", "url": "https://www.uniprot.org/uniprotkb/E1BM19/entry#A0AAA9S5Y0-1", "sequence": { "sequence": "MQKKPGFKMEMYETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIKFLKQFRHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLPQVQHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFIEKFIPELKAKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSVWGKELEKEKRPKEIKVRVTKVKGGKGDILEPKKIVCEGGHCQQVAAEIAHTMSQDTKPVISEPPNPVNPSTNAIGMKDDPCAGGGMVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQVISNRHEDTGSTQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQSKEMKGMEVKQIKVLKRESKRTDSSKIPTLLNADQYQEKQENTGNAQTERKKNLPDVE", "length": 597, "header": "tr|A0AAA9S5Y0-1|E1BM19_BOVIN Computationally mapped isoform of Cyclin-dependent kinase-like 3 OS=Bos taurus OX=9913 GN=CDKL3 PE=3 SV=1 CANONICAL=E1BM19-1" }, "locus": { "chromosome": "7", "start_pos": 45942066, "end_pos": 45910683, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093654.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093654.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081339.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081339.1" } ] } }, { "isoform_ac": "A0ABI0P4I6-1", "url": "https://www.uniprot.org/uniprotkb/E1BM19/entry#A0ABI0P4I6-1", "sequence": { "sequence": "MQKKPGFKMEMYETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIKFLKQFRHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLPQVQHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFIEKFIPELKAKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSVWGKELEKEKRPKEIKVRVTKVKGGKGDILEPKKIVCEGGHCQQVAAEIAHTMSQDTKPVISEPPNPVNPSTNAIGMKDDPCAGGGMVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQVISNRHEDTGSTQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQSKEMKGMEAHDLFSSFIIN", "length": 558, "header": "tr|A0ABI0P4I6-1|A0ABI0P4I6_BOVIN Computationally mapped isoform of Cyclin-dependent kinase-like 3 OS=Bos taurus OX=9913 GN=CDKL3 PE=3 SV=1 CANONICAL=E1BM19-1" }, "locus": { "chromosome": "7", "start_pos": 45942066, "end_pos": 45912861, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151774.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151774.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105906.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105906.1" } ] } }, { "isoform_ac": "E1BM19-1", "url": "https://www.uniprot.org/uniprotkb/E1BM19/entry#E1BM19-1", "sequence": { "sequence": "MQKKPGFKMEMYETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIKFLKQFRHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLPQVQHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFIEKFIPELKAKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSVWGKELEKEKRPKEIKVRVTKVKGGKGDILEPKKIVCEGGHCQQVAAEIAHTMSQDTKPVISEPPNPVNPSTNAIGMKDDPCAGGGMVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQVISNRHEDTGSTQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQSKEMKGMEVKQIKVLKRESKRTDSSKIPTLLNADQYQEKQEDGDGHCKGKNLKRNRLFFWFLRRQVRWSGTFISFTNYP", "length": 618, "header": "tr|E1BM19-1|E1BM19_BOVIN Isoform 1 of Cyclin-dependent kinase-like 3 OS=Bos taurus OX=9913 GN=CDKL3 PE=3 SV=3 CANONICAL=E1BM19-1" }, "locus": { "chromosome": "7", "start_pos": 45942066, "end_pos": 45907282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014574.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014574.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014574.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014574.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BM19", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "E1BM19", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E1BM19", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BM19", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BM19", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of dendrite morphogenesis", "id": "GO:0050775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050775", "evidence": [ { "database": "UniProtKB", "id": "E1BM19", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ], "pmid": "" }, { "name": "dendrite extension", "id": "GO:0097484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097484", "evidence": [ { "database": "UniProtKB", "id": "E1BM19", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ], "pmid": "" }, { "name": "negative regulation of axon extension", "id": "GO:0030517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030517", "evidence": [ { "database": "UniProtKB", "id": "E1BM19", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", 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"A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BN91-1", "uniprot_ac": "E1BN91", "uniprot_id": "E1BN91_BOVIN", "mass": { "chemical_mass": 94175.0, "monoisotopic_mass": 94175.0 }, "refseq": { "ac": "NP_001179523", "name": "probable ribonuclease ZC3H12B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179523" }, "gene_names": [ { "name": "ZC3H12B", "type": "recommended", "evidence": [ { "id": "E1BN91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN91" } ] }, { "name": "ZC3H12B", "type": "synonym", "evidence": [ { "id": "NP_001179523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179523" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH-type containing 12B", "type": "synonym", "evidence": [ { "id": "E1BN91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN91/entry#names_and_taxonomy" } ] }, { "name": "probable ribonuclease ZC3H12B", "type": "synonym", "evidence": [ { "id": "NP_001179523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179523" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN91", "url": "https://www.uniprot.org/uniprotkb/E1BN91" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZC3H12B", "url": "https://www.uniprot.org/uniprotkb/E1BN91", "locus": { "chromosome": "X", "start_pos": 94980161, "end_pos": 95036500, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002206", "url": "https://www.ensembl.org/id/ENSBTAG00000002206" } ] } } ], "crossref": [ { "id": "E1BN91", "url": "https://alphafold.ebi.ac.uk/entry/E1BN91", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002206", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002206", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18729", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18729", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "524199", "url": "https://www.ncbi.nlm.nih.gov/gene/524199", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524199", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524199", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDPLPCT", "url": "https://omabrowser.org/oma/group/WDPLPCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN91", "url": "https://www.orthodb.org/?gene=E1BN91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12876", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12876", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12876:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12876:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11977", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11977", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179523", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S7J4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7J4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN91", "url": "https://www.uniprot.org/uniprotkb/E1BN91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN91-1", "url": "https://www.uniprot.org/uniprotkb/E1BN91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTATAAVETPKMKKSASKEEKQQSKQENTEQGNADSEEWLGCESDPEQMSLKKSNSDNRCQLGDVQLNKKDILSKPHRQLCRSPCLDHPSFSQSSILHDGKLDLEKEYQTKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDLEGQVNLNLLGPRGPSSREITSPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGLSSAKGDITSEVKRVTPKRQSDPSIRSVAVEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFSHQKSSLEHMTSMQYPPILVTNSHGTPISYAEQYPKFEPLGDHSYYSVLGDFSKLNINSMHNREYYMAEADRGLYARNPNLCPDNRMSHTRNDNYSSYNNLYLAVADTHPEGSLKLHRSASQNHLQPFPHGYHEALTRVQSYGPEDSKQGPHKQSVSHLVLHAQHPTNGARSSCPGDYPMPPNIHPGATPQPGRALVMTRMDSISDSRLYENNPMRQRRPPLCREQHASWDPLPCATDSYGYHSYPLSNSLMQPCYEPVMVRSVPEKMEQLWMNPWVGMCNDSREQMIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVSKLRAAH", "length": 836, "header": "tr|E1BN91-1|E1BN91_BOVIN Isoform 1 of Zinc finger CCCH-type containing 12B OS=Bos taurus OX=9913 GN=ZC3H12B PE=3 SV=3 CANONICAL=E1BN91-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S7J4-1", "url": "https://www.uniprot.org/uniprotkb/E1BN91/entry#A0AAA9S7J4-1", "sequence": { "sequence": "MTATAAVETPKMKKSASKEEKQQSKQENTEQGNADSEEWLGCESDPEQMSLKKSNSDNRCQLGDVQLNKKDILSKPHRQLCRSPCLDHPSFSQSSILHDGKLDLEKEYQTKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDLEGQVNLNLLGPRGPSSREITSPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGLSSAKGDFSKLNINSMHNREYYMAEADRGLYARNPNLCPDNRMSHTRNDNYSSYNNLYLAVADTHPEGSLKLHRSASQNHLQPFPHGYHEALTRVQSYGPEDSKQGPHKQSVSHLVLHAQHPTNGARSSCPGDYPMPPNIHPGATPQPGRALVMTRMDSISDSRLYENNPMRQRRPPLCREQHASWDPLPCATDSYGYHSYPLSNSLMQPCYEPVMVRSVPEKMEQLWMNPWVGMCNDSREQMIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVSKLRAAH", "length": 707, "header": "tr|A0AAA9S7J4-1|E1BN91_BOVIN Computationally mapped isoform of Zinc finger CCCH-type containing 12B OS=Bos taurus OX=9913 GN=ZC3H12B PE=3 SV=1 CANONICAL=E1BN91-1" }, "locus": { "chromosome": "X", "start_pos": 95033127, "end_pos": 94980269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116384.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116384.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081980.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081980.1" } ] } }, { "isoform_ac": "E1BN91-1", "url": "https://www.uniprot.org/uniprotkb/E1BN91/entry#E1BN91-1", "sequence": { "sequence": "MTATAAVETPKMKKSASKEEKQQSKQENTEQGNADSEEWLGCESDPEQMSLKKSNSDNRCQLGDVQLNKKDILSKPHRQLCRSPCLDHPSFSQSSILHDGKLDLEKEYQTKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDLEGQVNLNLLGPRGPSSREITSPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGLSSAKGDITSEVKRVTPKRQSDPSIRSVAVEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFSHQKSSLEHMTSMQYPPILVTNSHGTPISYAEQYPKFEPLGDHSYYSVLGDFSKLNINSMHNREYYMAEADRGLYARNPNLCPDNRMSHTRNDNYSSYNNLYLAVADTHPEGSLKLHRSASQNHLQPFPHGYHEALTRVQSYGPEDSKQGPHKQSVSHLVLHAQHPTNGARSSCPGDYPMPPNIHPGATPQPGRALVMTRMDSISDSRLYENNPMRQRRPPLCREQHASWDPLPCATDSYGYHSYPLSNSLMQPCYEPVMVRSVPEKMEQLWMNPWVGMCNDSREQMIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVSKLRAAH", "length": 836, "header": "tr|E1BN91-1|E1BN91_BOVIN Isoform 1 of Zinc finger CCCH-type containing 12B OS=Bos taurus OX=9913 GN=ZC3H12B PE=3 SV=3 CANONICAL=E1BN91-1" }, "locus": { "chromosome": "X", "start_pos": 95033127, "end_pos": 94980269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002858.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002858.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002858.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002858.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:524199", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524199", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PB60-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "ZC3H12B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTAWSMVGKLKMEKRHSREDRNVEQDAGECSAESEEWTSSESEPEQPYFRSSCSNIPWREKEVPPKPHRPLCRSPCLDRPSFSQSSITQDLKLEECKTNLDKEYQAKMDFALKLGYAGDQIQAVLNKLGADALINDVLAELVRLGNKSESEGQNSASSTTSTLVPRGPCPKEIASPELSLEDEVVDNSDNLRPIVIDGSNVAMSHGNKEGFSCRGIQLAVDWFLEKGHKDITVFVPAWRKEQSRPDAPITDQEILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQNEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVIPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSAVKTMSEGALAKCGTGPSSSKGEISSEVKRIAPKRQSDPSIRSVAVEPEEKLTVARKSEANSVPSLVSALSVPTLPPPKSHAAGALNTRSASSPVPGSSQFTHQKSSLEHMSSVQYPPILVTNSHGTSISYTDQYPKYESLGDHGYYSLLSDFSNLSISSMHNTDYYGADMDQGMYSRNSSPCPDNCLSHTNNDSYSSYNDLYLGVADASPEDNVKIHRLTSQNRLQPFPHGYHEALNRVQSFGTEEPQQSLRKQSVSHLGLHAQHPVVGARSSCPGEYPVPQNIHPSTAQPSRALVMTRMDSISDSRLYESNPTRQRRPPLCREQHASWDPLPCASDSYTYHSYPLSNNLMQPCYEPVMVRSMPEKMEQLWRNPWIGICGEPREPHIIPEHQYQTYKNLCNIFPPSIVLSVMEKNPHMTDAQQLAAMIVAKLRTGR", "length": 837 }, "evidence": [ { "id": "E1BN91", "url": "https://omabrowser.org/oma/group/E1BN91/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ACQ4-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "Zc3h12b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTATAAVETPKMEKSASKEEKHQPKQKGSTDRDNADPEEWVNSESDPEPMSFKSGHNSNQSADIQLKKKEMPSKPHRPLCRSPCLDRPSFSQSSILQDGKLDLEKEYQAKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDSEAQVNLSLLLPRGASSREIASPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKIMSEDTLAKCGTGMSTAKGEITSEIKRVASKRQSDPSIRSVAVEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFPHQKASLEHMVSMQYPPILVTNSHGTPINYTEQYPKFETMGDHDYYSVLSDFSKLSINNMHNHEYYMAEANQGVYVRNPGLCTDSHMSHTRNDNYSSYNNLYLAVADAHPEGTLKLHRAASHNHLQPFSHGYHEALARVQSYGSEDSKQAPHKQSVPHLALHTQNPATGAHSSCPGDYTMPPNIHPVGPSQPGRALVMTRMDSISDSRLYDSNPMRQRRPPLCREQHASWDPLPCTADSYGYHSYPLGNSLMQPCYEPVMVRSMPEKMEQLWRNPWVGMCNDSREHMIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVAKLRAAR", "length": 835 }, "evidence": [ { "id": "E1BN91", "url": "https://omabrowser.org/oma/group/E1BN91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RTN0-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "ZC3H12B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTATAAVETPKMKKSASKEEKQQPKQDSTEQGNADYEEWLSPETDTEHLNLKSRNNDNSCQLGDVQLKKKEIPSKPHRQLCRSPCLDHPSFSQSSILQDGKIDLEKEYQAKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDLEGQVNLSVLMPRGPSSREIASPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGLSSAKGEITSEVKRVAPKRQSDPSIRSVAVEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFSHQKSSLEHMTSMQYPPILVTNSHGTPISYAEQYPKFESLGDHGYYSVLGDFSKLSINSMHNRDYYMAEADRGLYARNPSLCPDNRMSHTRNDNYSSYNNLYLAVADTHSEGNLKLHRSASQNHLQPFPHGYHEALTRVQSYGPEDSKQAPHKQSVPHLVLHAQHPATGARSSCPGDYPMLPNVHPGATPQPGRALVMTRMDSISDSRLYESNPMRQRRPPLCREQHASWDPLPCATDSYGYHSYPLSNSLMQPCYEPVMVRSVPEKMEQLWRNPWVGMCNDSREHVIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVSKLRAAR", "length": 836 }, "evidence": [ { "id": "E1BN91", "url": "https://omabrowser.org/oma/group/E1BN91/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3X9I7-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "Zc3h12b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTATAAVETPKMEKSASKEEKQQPKQEDSTDRGNADPEEWANSESDPEQMSCKSGHTSYQATDIQLKKKEMPSKPHRPLCRSPCLDRPSFSQSSILQDGKLDLEKEYQAKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDSEAQVNLSLLLPRGASSREIASPELSLEDEIDNSDNLRPIVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKIMSEDTLAKCGAGMSTAKGEITSEIKRVASKRQSDPSIRSVAVEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFPHQKASLEHMVSMQYPPILVTNSHGTPINYTEQYPKFETMGDHDYYSVLSDFSKLSINNMHNHEYYMAEANQGVYVRNPGLCTDSHMSHTRNDNYSSYNNLYLAVADAHPEGTLKLHRSASHNHLQPFSHGYHEALARVQSYGSEDSKQAPHKQSVPHLAVHTQNPATGAHSSCPGDYTMPPSIHPVGPSQPGRALVMTRMDSISDSRLYDSNPMRQRRPPLCREQHASWDPLPCTADSYGYHSYPLGNSLMQPCYEPVMVRSMPEKMEQLWRNPWVGMCNDSREHMIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVAKLRAAR", "length": 835 }, "evidence": [ { "id": "E1BN91", "url": "https://omabrowser.org/oma/group/E1BN91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5HYM0-1", "protein_name": "Probable ribonuclease ZC3H12B", "gene_name": "ZC3H12B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTATAEVETPKMEKSASKEEKQQPKQDSTEQGNADSEEWMSSESDPEQISLKSSDNSKSCQPRDGQLKKKEMHSKPHRQLCRSPCLDRPSFSQSSILQDGKLDLEKEYQAKMEFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDSEGQINLSLLVPRGPSSREIASPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPIVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGMSSAKGEITSEVKRVAPKRQSDPSIRSVAMEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFPHQKASLEHMASMQYPPILVTNSHGTPISYAEQYPKFESMGDHGYYSMLGDFSKLNINSMHNREYYMAEVDRGVYARNPNLCSDSRVSHTRNDNYSSYNNVYLAVADTHPEGNLKLHRSASQNRLQPFPHGYHEALTRVQSYGPEDSKQGPHKQSVPHLALHAQHPSTGTRSSCPADYPMPPNIHPGATPQPGRALVMTRMDSISDSRLYESNPVRQRRPPLCREQHASWDPLPCTTDSYGYHSYPLSNSLMQPCYEPVMVRSVPEKMEQLWRNPWVGMCNDSREHMIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVAKLRAAR", "length": 836 }, "evidence": [ { "id": "E1BN91", "url": "https://omabrowser.org/oma/group/E1BN91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BN91", "url": "https://www.uniprot.org/uniprotkb/E1BN91" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1BN91", "url": "https://www.uniprot.org/uniprotkb/E1BN91" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "E1BN91", "url": "https://www.uniprot.org/uniprotkb/E1BN91" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1BN91", "url": "https://www.uniprot.org/uniprotkb/E1BN91" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "E1BN91", "url": "https://www.uniprot.org/uniprotkb/E1BN91" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BN91", "url": "https://www.uniprot.org/uniprotkb/E1BN91" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "E1BN91", "url": "https://www.uniprot.org/uniprotkb/E1BN91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "E1BN91", "url": "https://www.uniprot.org/uniprotkb/E1BN91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN91-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 836, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN91-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN91" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN91" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 355, "end_pos": 380, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 594, "end_pos": 596 }, { "start_pos": 781, "end_pos": 783 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMV3-1", "uniprot_ac": "E1BMV3", "uniprot_id": "MATN1_BOVIN", "mass": { "chemical_mass": 59014.0, "monoisotopic_mass": 59014.0 }, "refseq": { "ac": "XP_059749074", "name": "cartilage matrix protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059749074" }, "gene_names": [ { "name": "MATN1", "type": "recommended", "evidence": [ { "id": "E1BMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMV3" } ] }, { "name": "CMP", "type": "synonym", "evidence": [ { "id": "E1BMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMV3" } ] }, { "name": "MATN1", "type": "synonym", "evidence": [ { "id": "XP_059749074", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059749074" } ] } ], "protein_names": [ { "name": "Matrilin-1", "type": "recommended", "evidence": [ { "id": "E1BMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMV3/entry#names_and_taxonomy" } ] }, { "name": "Cartilage matrix protein", "type": "synonym", "evidence": [ { "id": "E1BMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMV3/entry#names_and_taxonomy" } ] }, { "name": "cartilage matrix protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059749074", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059749074" } ] } ], "function": [ { "annotation": "A major component of the extracellular matrix of non-articular cartilage (By similarity). Binds to type 2 collagens and forms long concatenated protein networks as part of the extracellular matrix (By similarity). Required for the network-like organization and bundling of collagen fibrils surrounding chondrocytes in the zones of maturation and hypertrophy (By similarity). Required for mechanotransduction and adaption to mechanical loading in cartilage chondrocytes, resulting in an increase in expression of the extracellular matrix components ACAN and COL2A1 (By similarity). Acts as a moderator of angiogenesis in response to injury (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "E1BMV3", "url": "https://www.uniprot.org/uniprotkb/E1BMV3#function" }, { "database": "UniProtKB", "id": "P51942", "url": "https://www.uniprot.org/uniprotkb/P51942#function" }, { "database": "UniProtKB", "id": "P05099", "url": "https://www.uniprot.org/uniprotkb/P05099#function" } ] }, { "annotation": "A major component of the extracellular matrix of non-articular cartilage. Binds to type 2 collagens and forms long concatenated protein networks as part of the extracellular matrix. Required for the network-like organization and bundling of collagen fibrils surrounding chondrocytes in the zones of maturation and hypertrophy. Required for mechanotransduction and adaption to mechanical loading in cartilage chondrocytes, resulting in an increase in expression of the extracellular matrix components ACAN and COL2A1. Acts as a moderator of angiogenesis in response to injury.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S8J5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8J5#function" }, { "database": "UniProtKB", "id": "ARBA00093320", "url": "https://www.uniprot.org/uniprotkb/ARBA00093320#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMV3", "url": "https://www.uniprot.org/uniprotkb/E1BMV3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MATN1", "url": "https://www.uniprot.org/uniprotkb/E1BMV3", "locus": { "chromosome": "2", "start_pos": 122858714, "end_pos": 122848955, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003479", "url": "https://www.ensembl.org/id/ENSBTAG00000003479" } ] } } ], "crossref": [ { "id": "E1BMV3", "url": "https://alphafold.ebi.ac.uk/entry/E1BMV3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003479", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003479", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01475", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01475", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512059", "url": "https://www.ncbi.nlm.nih.gov/gene/512059", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "E1BMV3", "url": "https://www.ebi.ac.uk/intact/interactors/id:E1BMV3*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BMV3", "url": "https://www.orthodb.org/?gene=E1BMV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059749074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059749074", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S8J5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8J5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8J5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMV3", "url": "https://www.uniprot.org/uniprotkb/E1BMV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMV3-1", "url": "https://www.uniprot.org/uniprotkb/E1BMV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRALSGPRLMLCGLLLLLFQAPCALGLAPLSRGHLCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGLVNYASSVKQEFPLRAHSSKAELLQAVRRIQPLSTGTMTGLAIQFAITKALSDAEGGRPRSPDISKVVIVVTDGRPQDSVRDVSARARAGGIELFAIGVGRVDKATLQQIASEPQDEHVDYVESYSVIEKLSKKFQEAFCLVSDLCATGDHDCEQVCVSSPGSYTCACREGFTLNSDGKTCNVCNGGGGSSATDLVFLIDGSKSVRPENFELVKKFINQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRSQDYINDAAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAEHYFYTADFKTINQIGKKLQKRICVEEDPCACESIVKFQTKVEGLLQALTRKHILSQKPLRGEGAVRRALWWRGGESLAPCVVGSGRLLLKTGWILAREAGLGFGTEKGEAETKS", "length": 544, "header": "sp|E1BMV3-1|MATN1_BOVIN Isoform 1 of Matrilin-1 OS=Bos taurus OX=9913 GN=MATN1 PE=1 SV=4 CANONICAL=E1BMV3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S8J5-1", "url": "https://www.uniprot.org/uniprotkb/E1BMV3/entry#A0AAA9S8J5-1", "sequence": { "sequence": "MRALSGPRLMLCGLLLLLFQAPCALGLAPLSRGHLCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGLVNYASSVKQEFPLRAHSSKAELLQAVRRIQPLSTGTMTGLAIQFAITKALSDAEGGRPRSPDISKVVIVVTDGRPQDSVRDVSARARAGGIELFAIGVGRVDKATLQQIASEPQDEHVDYVESYSVIEKLSKKFQEAFCFCNGGGGSSATDLVFLIDGSKSVRPENFELVKKFINQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRSQDYINDAAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAEHYFYTADFKTINQIGKKLQKRICVEEDPCACESIVKFQTKVEGLLQALTRKHILSQKPLRGEGAVRRALWWRGGESLAPCVVGSGRLLLKTGWILAREAGLGFGTEKGEAETKS", "length": 502, "header": "tr|A0AAA9S8J5-1|MATN1_BOVIN Computationally mapped isoform of Matrilin-1 OS=Bos taurus OX=9913 GN=MATN1 PE=1 SV=1 CANONICAL=E1BMV3-1" }, "locus": { "chromosome": "2", "start_pos": 122857812, "end_pos": 122849003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097041.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097041.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082364.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082364.1" } ] } }, { "isoform_ac": "E1BMV3-1", "url": "https://www.uniprot.org/uniprotkb/E1BMV3/entry#E1BMV3-1", "sequence": { "sequence": "MRALSGPRLMLCGLLLLLFQAPCALGLAPLSRGHLCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGLVNYASSVKQEFPLRAHSSKAELLQAVRRIQPLSTGTMTGLAIQFAITKALSDAEGGRPRSPDISKVVIVVTDGRPQDSVRDVSARARAGGIELFAIGVGRVDKATLQQIASEPQDEHVDYVESYSVIEKLSKKFQEAFCLVSDLCATGDHDCEQVCVSSPGSYTCACREGFTLNSDGKTCNVCNGGGGSSATDLVFLIDGSKSVRPENFELVKKFINQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRSQDYINDAAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAEHYFYTADFKTINQIGKKLQKRICVEEDPCACESIVKFQTKVEGLLQALTRKHILSQKPLRGEGAVRRALWWRGGESLAPCVVGSGRLLLKTGWILAREAGLGFGTEKGEAETKS", "length": 544, "header": "sp|E1BMV3-1|MATN1_BOVIN Isoform 1 of Matrilin-1 OS=Bos taurus OX=9913 GN=MATN1 PE=1 SV=4 CANONICAL=E1BMV3-1" }, "locus": { "chromosome": "2", "start_pos": 122857812, "end_pos": 122849003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043181.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043181.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040771.5", "url": "https://www.ensembl.org/id/ENSBTAP00000040771.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 345, "start_aa": "Asn", "end_pos": 345, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn345", "evidence": [ { "id": "E1BMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMV3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 77, "start_aa": "Asn", "end_pos": 77, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn77", "evidence": [ { "id": "E1BMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMV3#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Interaction of cartilage matrix protein with aggrecan. Increased covalent cross-linking with tissue maturation.", "journal": "J. Biol. Chem.", "date": "1996", "authors": "Hauser N, Paulsson M, Heinegard D, Morgelin M", "evidence": [ { "database": "UniProtKB", "id": "E1BMV3", "url": "https://www.uniprot.org/uniprotkb/E1BMV3" } ], "reference": [ { "type": "PubMed", "id": "8943283", "url": "https://glygen.org/publication/PubMed/8943283" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "E1BMV3", "url": "https://www.uniprot.org/uniprotkb/E1BMV3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "E1BMV3", "url": "https://www.uniprot.org/uniprotkb/E1BMV3" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BMV3", "url": "https://www.uniprot.org/uniprotkb/E1BMV3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BMV3", "url": "https://www.uniprot.org/uniprotkb/E1BMV3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMV3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 544, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMV3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMV3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMV3" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000255", "start_pos": 224, "end_pos": 264, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMV3" }, { "id": "PRU00219", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00219" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA 1", "eco_id": "ECO_0000255", "start_pos": 42, "end_pos": 217, "start_aa": "Asp", "end_aa": "Phe", 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"https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BNQ6", "url": "https://www.orthodb.org/?gene=E1BNQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S9N5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9N5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9N5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNQ6", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNQ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTQLVARVQGTGCAGAEDQPPGPLGLGAKGVEGAGSREAALAPRAPWMAWQVSVPELEDRLQCPMCLEVFKEPLMLQCGHSYCKGCLVSLSHHLASELRCPVCRQEVDYSSSPPNVSLAKVIEALRLPGDPEPQVCAHHRNPLSLFCEKDQELICGLCGLLGAHQHHRVTPVSTVYSRMKEELAALISDLKQEQKKVDEQIAKLVNNRTRIVNESDVFSWVIRREFQELHHLVDEEKARCLEGVEGHTRGLVASLDMQLEQARGAQERLVQATGVLEQFGSESHHEFIRKYHAMASRPELQQARLSEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPESLKLDPATAHPLLELSKGNTVVQCGLLAQRRASQPERFDYSTCVLTSRGFSCGRHYWEVVVGSKSDWRLGVIKGTASRKGKLSKSPEHGVWLIGLKEGRVYEAFGCPRVPLPVAGHPHRIGIYLHYEQGELTFFDADRPDDLRPLYSFQADFQGKLYPILDTCWHERGSNSLPMVLPPPSGPGHLSPLQPTKL", "length": 534, "header": "tr|E1BNQ6-1|E1BNQ6_BOVIN Isoform 1 of E3 ubiquitin-protein ligase TRIM50 OS=Bos taurus OX=9913 GN=TRIM50 PE=3 SV=2 CANONICAL=E1BNQ6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S9N5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6/entry#A0AAA9S9N5-1", "sequence": { "sequence": "MAWQVSVPELEDRLQCPMCLEVFKEPLMLQCGHSYCKGCLVSLSHHLASELRCPVCRQEVDYSSSPPNVSLAKVIEALRLPGDPEPQVCAHHRNPLSLFCEKDQELICGLCGLLGAHQHHRVTPVSTVYSRMKEELAALISDLKQEQKKVDEQIAKLVNNRTRIVNESDVFSWVIRREFQELHHLVDEEKARCLEGVEGHTRGLVASLDMQLEQARGAQERLVQATGVLEQFGSESHHEFIRYHAMASRY", "length": 250, "header": "tr|A0AAA9S9N5-1|E1BNQ6_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM50 OS=Bos taurus OX=9913 GN=TRIM50 PE=3 SV=1 CANONICAL=E1BNQ6-1" }, "locus": { "chromosome": "25", "start_pos": 33813311, "end_pos": 33808726, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095526.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095526.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082792.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082792.1" } ] } }, { "isoform_ac": "E1BNQ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6/entry#E1BNQ6-1", "sequence": { "sequence": "MTQLVARVQGTGCAGAEDQPPGPLGLGAKGVEGAGSREAALAPRAPWMAWQVSVPELEDRLQCPMCLEVFKEPLMLQCGHSYCKGCLVSLSHHLASELRCPVCRQEVDYSSSPPNVSLAKVIEALRLPGDPEPQVCAHHRNPLSLFCEKDQELICGLCGLLGAHQHHRVTPVSTVYSRMKEELAALISDLKQEQKKVDEQIAKLVNNRTRIVNESDVFSWVIRREFQELHHLVDEEKARCLEGVEGHTRGLVASLDMQLEQARGAQERLVQATGVLEQFGSESHHEFIRKYHAMASRPELQQARLSEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPESLKLDPATAHPLLELSKGNTVVQCGLLAQRRASQPERFDYSTCVLTSRGFSCGRHYWEVVVGSKSDWRLGVIKGTASRKGKLSKSPEHGVWLIGLKEGRVYEAFGCPRVPLPVAGHPHRIGIYLHYEQGELTFFDADRPDDLRPLYSFQADFQGKLYPILDTCWHERGSNSLPMVLPPPSGPGHLSPLQPTKL", "length": 534, "header": "tr|E1BNQ6-1|E1BNQ6_BOVIN Isoform 1 of E3 ubiquitin-protein ligase TRIM50 OS=Bos taurus OX=9913 GN=TRIM50 PE=3 SV=2 CANONICAL=E1BNQ6-1" }, "locus": { "chromosome": "25", "start_pos": 33816133, "end_pos": 33801154, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007623.5", "url": "https://www.ensembl.org/id/ENSBTAT00000007623.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007623.4", "url": "https://www.ensembl.org/id/ENSBTAP00000007623.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 170, "start_aa": "Thr", "end_pos": 170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr170", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ6", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ6", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ6", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ6", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ6", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983140" } ] }, { "id": "R-BTA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4I9-1", "E1BJS7-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q1JQA1-1", "Q29RQ5-1", "Q32LN5-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0AAA9RXI4-1", "Q4U5R4-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983147" } ] }, { "id": "R-BTA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983156" } ] }, { "id": "R-BTA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1MAR8", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] } ] }, { "uniprot_ac": "A0A3Q1MLB6", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] } ] }, { "uniprot_ac": "A0A3Q1MLH2", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] } ] }, { "uniprot_ac": "A0A3Q1N3G7", "gene_name": "TRIM36", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] } ] }, { "uniprot_ac": "A0AAA9RXI4", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] } ] }, { "uniprot_ac": "A0AAA9RXX2", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] } ] }, { "uniprot_ac": "A0AAA9RZ14", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] } ] }, { "uniprot_ac": "A0AAA9S100", "gene_name": "MKRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] } ] }, { "uniprot_ac": "A0AAA9TKS8", "gene_name": "RNF217", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] } ] }, { "uniprot_ac": "A0AAA9TWH7", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] } ] }, { "uniprot_ac": "A0AAF6DMH9", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] } ] }, { "uniprot_ac": "A0ABI0NWC8", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] } ] }, { "uniprot_ac": "A0JN74", "gene_name": "TRIM11", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] } ] }, { "uniprot_ac": "A1A4I9", "gene_name": "UFL1", "activity": [ { "ec_number": "2.3.2.-", "activity": "", "evidence": [ { "id": "A1A4I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I9" } ] } ] }, { "uniprot_ac": "A3KN22", "gene_name": "UBE2M", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] } ] }, { "uniprot_ac": "A5D7F8", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] } ] }, { "uniprot_ac": "A5PJC4", "gene_name": "UBE2L6", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] } ] }, { "uniprot_ac": "A5PKG6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] } ] }, { "uniprot_ac": "A6H795", "gene_name": "UBE2W", "activity": [ { "ec_number": "2.3.2.25", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein].", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] } ] }, { "uniprot_ac": "E1B782", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] } ] }, { "uniprot_ac": "E1B7D3", "gene_name": "TRIM39", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] } ] }, { "uniprot_ac": "E1B7G3", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] } ] }, { "uniprot_ac": "E1B7Q7", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] } ] }, { "uniprot_ac": "E1B8R6", "gene_name": "ARIH2", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] } ] }, { "uniprot_ac": "E1BAV2", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] } ] }, { "uniprot_ac": "E1BBN5", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] } ] }, { "uniprot_ac": "E1BBY2", "gene_name": "TRIM41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] } ] }, { "uniprot_ac": "E1BCU1", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] } ] }, { "uniprot_ac": "E1BCW1", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] } ] }, { "uniprot_ac": "E1BH71", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] } ] }, { "uniprot_ac": "E1BID7", "gene_name": "TRIM69", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] } ] }, { "uniprot_ac": "E1BIP5", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] } ] }, { "uniprot_ac": "E1BIW0", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] } ] }, { "uniprot_ac": "E1BJS7", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] } ] }, { "uniprot_ac": "E1BL26", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] } ] }, { "uniprot_ac": "E1BNQ6", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] } ] }, { "uniprot_ac": "E1BNY9", "gene_name": "HUWE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] } ] }, { "uniprot_ac": "F1MBM6", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] } ] }, { "uniprot_ac": "F1MEX6", "gene_name": "RNF19B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] } ] }, { "uniprot_ac": "F1MJ10", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] } ] }, { "uniprot_ac": "F1MJS5", "gene_name": "HECTD3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] } ] }, { "uniprot_ac": "F1MLS5", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] } ] }, { "uniprot_ac": "F1MM41", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] } ] }, { "uniprot_ac": "F1MTS8", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] } ] }, { "uniprot_ac": "F1MWS4", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] } ] }, { "uniprot_ac": "F1MYL0", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] } ] }, { "uniprot_ac": "F1N1X8", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] } ] }, { "uniprot_ac": "F1N3I3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] } ] }, { "uniprot_ac": "F1N495", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] } ] }, { "uniprot_ac": "F1N5G3", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] } ] }, { "uniprot_ac": "F1N645", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] } ] }, { "uniprot_ac": "F1N6G5", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] } ] }, { "uniprot_ac": "F1N703", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] } ] }, { "uniprot_ac": "F1N7A0", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] } ] }, { "uniprot_ac": "P61085", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] } ] }, { "uniprot_ac": "Q0II22", "gene_name": "RNF126", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] } ] }, { "uniprot_ac": "Q0P5K3", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] } ] }, { "uniprot_ac": "Q17QG5", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] } ] }, { "uniprot_ac": "Q1JQA1", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] } ] }, { "uniprot_ac": "Q1RML1", "gene_name": "UBE2S", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] } ] }, { "uniprot_ac": "Q1RMW1", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] } ] }, { "uniprot_ac": "Q1RMX2", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] } ] }, { "uniprot_ac": "Q29RQ5", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] } ] }, { "uniprot_ac": "Q2T9X7", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] } ] }, { "uniprot_ac": "Q2TA03", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] } ] }, { "uniprot_ac": "Q2TA10", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] } ] }, { "uniprot_ac": "Q32L27", "gene_name": "UBE2Q2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] } ] }, { "uniprot_ac": "Q32LN1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] } ] }, { "uniprot_ac": "Q32LN5", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] } ] }, { "uniprot_ac": "Q32P99", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] } ] }, { "uniprot_ac": "Q32PA5", "gene_name": "UBE2C", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] } ] }, { "uniprot_ac": "Q3MHP1", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] } ] }, { "uniprot_ac": "Q4U5R4", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] } ] }, { "uniprot_ac": "Q5E9J6", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] } ] }, { "uniprot_ac": "Q7YRV4", "gene_name": "TRIM21", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNQ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 534, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNQ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNQ6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 172, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" }, { "id": "PS50188", "database": "PROSITE", "url": 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Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 170 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 213, "end_pos": 215 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLB5-1", "uniprot_ac": "E1BLB5", "uniprot_id": "E1BLB5_BOVIN", "mass": { "chemical_mass": 110435.0, "monoisotopic_mass": 110435.0 }, "refseq": {}, "gene_names": [ { "name": "INPP5J", "type": "recommended", "evidence": [ { "id": "E1BLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A", "type": "recommended", "evidence": [ { "id": "E1BLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB5/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.36", "type": "synonym", "evidence": [ { "id": "E1BLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB5/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.56", "type": "synonym", "evidence": [ { "id": "E1BLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB5/entry#names_and_taxonomy" } ] }, { "name": "Inositol polyphosphate 5-phosphatase J", "type": "synonym", "evidence": [ { "id": "E1BLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB5/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylinositol 1,3,4,5-tetrakisphosphate 5-phosphatase", "type": "synonym", "evidence": [ { "id": "E1BLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB5/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylinositol 1,4,5-trisphosphate 5-phosphatase", "type": "synonym", "evidence": [ { "id": "E1BLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5#function" }, { "database": "UniProtKB", "id": "ARBA00059259", "url": "https://www.uniprot.org/uniprotkb/ARBA00059259#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "INPP5J", "url": "https://www.uniprot.org/uniprotkb/E1BLB5", "locus": { "chromosome": "17", "start_pos": 69982401, "end_pos": 69965267, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017023", "url": "https://www.ensembl.org/id/ENSBTAG00000017023" } ] } } ], "crossref": [ { "id": "E1BLB5", "url": "https://alphafold.ebi.ac.uk/entry/E1BLB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017023", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017023", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09094", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09094", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BLB5", "url": "https://www.orthodb.org/?gene=E1BLB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11200", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11200", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11200:SF127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11200:SF127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17751", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17751", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1855183", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855183", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1855204", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855204", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "11392", "url": "https://www.rhea-db.org/rhea/11392", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19797", "url": "https://www.rhea-db.org/rhea/19797", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "22764", "url": "https://www.rhea-db.org/rhea/22764", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SA84", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SA84-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLB5-1", "url": "https://www.uniprot.org/uniprotkb/E1BLB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFTDASRLNRLMTSLVPGSGGAGAGAGREPGAAWAADMEGRGDGGSRRPGTRAGLGPLPMPHGISQTGAPSKLPAKKSAPVPLEPRLALTPVGPRTAVPPSSEGPRLALVSPRPILAPASTPGGKKTAPAHRRSGLAPTSVGQLVMSASAGPKPPPATSGSVLAPTSLGQLLMPASTGPRPPSATPVPRLAPLSRDQKQVPPASMGPKPALAASGLSLAVTSEKQPPQPSSSPSAGPSPVLSPSQEQVLAPASVTPALASTGWTPAKQRDAPAPRPPPQSEGHLPAPAQASGAVSSPSFIQAPPDPRVSPSFRARPEVPRSSPEDPVLPRPPQTLPLDVGQGPPEPSTRSPGLLSPTFRPGAALAQTGPPPLPKPPRSPSRSPSRSPNRSPGVPPAPEMALPRPSSQGAGPGERLSPSLQPRETPVPVTTSSSTPTSSSSSWSAQPTCKSDPGFWITVVTWNVGTAMPPDDVTSLLHLGSTSDDSDRADMIAIGLQEVNSMINKRLKDALFTDQWSELFMDALGPFNFVLVSTVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSEQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRESHRLQVTQHSYRSHMEYTVSDHKPVAAQFVLHFAFRDDVPLVRLEVADEWARPEQAVVRYRIETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKHEDVDGSAYQVTFSEESLPKGHGDFILGYYSHTHGILIGVTEPFQISLPTSEPTSSSTDSSGTSSEDEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPTLALRPSSRERRGTSRSPSPQSRRLPRAAPDGAGNGGSRGSSEEGPPGLPGAWAFPPSVPRSLGLLPALRLETVDPGGGGCWGPDREALASSGSLSPSPQGRQGLEEGGLGP", "length": 1040, "header": "tr|E1BLB5-1|E1BLB5_BOVIN Isoform 1 of Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A OS=Bos taurus OX=9913 GN=INPP5J PE=3 SV=4 CANONICAL=E1BLB5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SA84-1", "url": "https://www.uniprot.org/uniprotkb/E1BLB5/entry#A0AAA9SA84-1", "sequence": { "sequence": "MEGRGDGGSRRPGTRAGLGPLPMPHGISQTGAPSKMDSRFQLPAKKSAPVPLEPRITVVTWNVGTAMPPDDVTSLLHLGSTSDDSDRADMIAIGLQEVNSMINKRLKDALFTDQWSELFMDALGPFNFVLVSTVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSEQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRESHRLQVTQHSYRSHMEYTVSDHKPVAAQFVLHFAFRDDVPLVRLEVADEWARPEQAVVRYRIETVFARSSWDWIGLYRVTFSEESLPKGHGDFILGYYSHTHGILIGVTEPFQISLPTSEPTSSSTDSSGTSSEDEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPTLALRPSSRERRGTSRSPSPQSRRLPRAAPDGAGNGGSRGSSEEGPPGLPGAWAFPPSVPRSLGLLPALRLETVDPGGGGCWGPDREALASSGSLSPSPQGRQGLEEGGLGP", "length": 613, "header": "tr|A0AAA9SA84-1|E1BLB5_BOVIN Computationally mapped isoform of Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A OS=Bos taurus OX=9913 GN=INPP5J PE=3 SV=1 CANONICAL=E1BLB5-1" }, "locus": { "chromosome": "17", "start_pos": 69982366, "end_pos": 69972470, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127110.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127110.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079088.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079088.1" } ] } }, { "isoform_ac": "E1BLB5-1", "url": "https://www.uniprot.org/uniprotkb/E1BLB5/entry#E1BLB5-1", "sequence": { "sequence": 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"length": 1040, "header": "tr|E1BLB5-1|E1BLB5_BOVIN Isoform 1 of Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A OS=Bos taurus OX=9913 GN=INPP5J PE=3 SV=4 CANONICAL=E1BLB5-1" }, "locus": { "chromosome": "17", "start_pos": 69982366, "end_pos": 69965355, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022635.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022635.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022635.6", "url": "https://www.ensembl.org/id/ENSBTAP00000022635.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 122, "start_aa": "Thr", "end_pos": 122, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr122", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 186, "start_aa": "Thr", "end_pos": 186, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr186", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 256, "start_aa": "Thr", "end_pos": 256, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr256", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-BTA-1855183", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855183", "resource": "Reactome", "description": "Synthesis of IP2, IP, and Ins in the cytosol" }, { "id": "R-BTA-1855204", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855204", "resource": "Reactome", "description": "Synthesis of IP3 and IP4 in the cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" }, { "name": "negative regulation of microtubule polymerization", "id": "GO:0031115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031115", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "id": "GO:0004439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004439", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" }, { "name": "inositol-polyphosphate 5-phosphatase activity", "id": "GO:0004445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004445", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "id": "GO:0034485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034485", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" }, { "name": "inositol trisphosphate phosphatase activity", "id": "GO:0046030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046030", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" }, { "name": "dendritic shaft", "id": "GO:0043198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043198", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "E1BLB5", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11392", "name": "", "equation": "1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9U0Y4-1", "E1BLB5-1", "O18964-1" ], "evidence": [ { "id": "11392", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11392" } ] }, { "id": "19797", "name": "", "equation": "1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9U0Y4-1", "E1BLB5-1", "O18964-1", "A0A3Q1LUU0-1" ], "evidence": [ { "id": "19797", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19797" } ] }, { "id": "22764", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1MIH5-1", "F1N1U1-1", "O18964-1", "A0A3Q1LUU0-1", "A0AAA9U0Y4-1", "E1BAU6-1", "E1BLB5-1" ], "evidence": [ { "id": "22764", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22764" } ] }, { "id": "R-BTA-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BBJ7-1", "E1BLB5-1" ], "evidence": [ { "id": "R-BTA-1675949", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1675949" } ] }, { "id": "R-BTA-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N1U1-1", "E1BLB5-1" ], "evidence": [ { "id": "R-BTA-1676177", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1676177" } ] }, { "id": "R-BTA-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BLB5-1" ], "evidence": [ { "id": "R-BTA-1855174", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855174" } ] }, { "id": "R-BTA-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P0C0T1-1", "E1BBJ7-1", "E1BLB5-1" ], "evidence": [ { "id": "R-BTA-1855218", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855218" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LUU0", "gene_name": "INPP5B", "activity": [ { "ec_number": "3.1.3.56", "activity": "1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.", "evidence": [ { "id": "A0A3Q1LUU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU0" } ] }, { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "A0A3Q1LUU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU0" } ] }, { "ec_number": "3.1.3.56", "activity": "", "evidence": [ { "id": "A0A3Q1LUU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU0" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "A0A3Q1LUU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU0" } ] } ] }, { "uniprot_ac": "A0A3Q1MIH5", "gene_name": "SYNJ1", "activity": [ { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "A0A3Q1MIH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIH5" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "A0A3Q1MIH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIH5" } ] } ] }, { "uniprot_ac": "A0AAA9U0Y4", "gene_name": "OCRL", "activity": [ { "ec_number": "3.1.3.86", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0Y4" } ] }, { "ec_number": "3.1.3.56", "activity": "1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.", "evidence": [ { "id": "A0AAA9U0Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0Y4" } ] }, { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0Y4" } ] }, { "ec_number": "3.1.3.56", "activity": "", "evidence": [ { "id": "A0AAA9U0Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0Y4" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "A0AAA9U0Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0Y4" } ] }, { "ec_number": "3.1.3.86", "activity": "", "evidence": [ { "id": "A0AAA9U0Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0Y4" } ] } ] }, { "uniprot_ac": "E1BAU6", "gene_name": "INPP5E", "activity": [ { "ec_number": "3.1.3.86", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.", "evidence": [ { "id": "E1BAU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAU6" } ] }, { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "E1BAU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAU6" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "E1BAU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAU6" } ] }, { "ec_number": "3.1.3.86", "activity": "", "evidence": [ { "id": "E1BAU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAU6" } ] } ] }, { "uniprot_ac": "E1BBJ7", "gene_name": "INPPL1", "activity": [ { "ec_number": "3.1.3.86", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.", "evidence": [ { "id": "E1BBJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBJ7" } ] }, { "ec_number": "3.1.3.86", "activity": "", "evidence": [ { "id": "E1BBJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBJ7" } ] } ] }, { "uniprot_ac": "E1BLB5", "gene_name": "INPP5J", "activity": [ { "ec_number": "3.1.3.56", "activity": "1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.", "evidence": [ { "id": "E1BLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ] }, { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "E1BLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "E1BLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ] }, { "ec_number": "3.1.3.56", "activity": "", "evidence": [ { "id": "E1BLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB5" } ] } ] }, { "uniprot_ac": "F1N1U1", "gene_name": "SYNJ2", "activity": [ { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "F1N1U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1U1" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "F1N1U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1U1" } ] } ] }, { "uniprot_ac": "O18964", "gene_name": "SYNJ1", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "O18964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18964" } ] }, { "ec_number": "3.1.3.95", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate.", "evidence": [ { "id": "O18964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18964" } ] }, { "ec_number": "3.1.3.36", 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"Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.56", "ec_name": "1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.", "evidence": [ { "id": "3.1.3.56", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56" }, { "id": "3.1.3.56", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.56" } ] }, { "ec_number": "3.1.3.36", "ec_name": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "3.1.3.36", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36" }, { "id": "3.1.3.36", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.36" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 122, 186, 256 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 389, "end_pos": 391 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"https://www.uniprot.org/uniprotkb/E1BLU2", "locus": { "chromosome": "16", "start_pos": 37095531, "end_pos": 37128285, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020266", "url": "https://www.ensembl.org/id/ENSBTAG00000020266" } ] } } ], "crossref": [ { "id": "E1BLU2", "url": "https://alphafold.ebi.ac.uk/entry/E1BLU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020266", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020266", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "532860", "url": "https://www.ncbi.nlm.nih.gov/gene/532860", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532860", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532860", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYRCRPL", "url": "https://omabrowser.org/oma/group/CYRCRPL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BLU2", "url": "https://www.orthodb.org/?gene=E1BLU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10686", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10686", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10686:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10686:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-196819", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196819", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192939", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192939", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SDA6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDA6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLU2", "url": "https://www.uniprot.org/uniprotkb/E1BLU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLU2-1", "url": "https://www.uniprot.org/uniprotkb/E1BLU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVPGPVSRRAAAAATMLLRTARVPRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVVDLSMYQKVTSYCRSATLVGFTVGSVLGQILVSVASWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHVPPSCQGTNGIKIQNGGVATDTAASNHRPQWEDVESKIPLNREEPPVEEQESKPDRLLVLKVLWNDFLVCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEQVMPSRHAAIYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGELTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFFIYAGYFALIAVVFLANGTVSIMKKYRKQEDPESSSQETPS", "length": 496, "header": "tr|E1BLU2-1|E1BLU2_BOVIN Isoform 1 of Thiamine transporter 1 OS=Bos taurus OX=9913 GN=SLC19A2 PE=3 SV=1 CANONICAL=E1BLU2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SDA6-1", "url": "https://www.uniprot.org/uniprotkb/E1BLU2/entry#A0AAA9SDA6-1", "sequence": { "sequence": "MVVPGPVSRRAAAAATMLLRTARVPRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGPDKNLTEREESKPDRLLVLKVLWNDFLVCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEQVMPSRHAAIYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGELTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFFIYAGYFALIAVVFLANGTVSIMKKYRKQEDPESSSQETPS", "length": 295, "header": "tr|A0AAA9SDA6-1|E1BLU2_BOVIN Computationally mapped isoform of Thiamine transporter 1 OS=Bos taurus OX=9913 GN=SLC19A2 PE=3 SV=1 CANONICAL=E1BLU2-1" }, "locus": { "chromosome": "16", "start_pos": 37128086, "end_pos": 37096402, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099246.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099246.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081829.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081829.1" } ] } }, { "isoform_ac": "E1BLU2-1", "url": "https://www.uniprot.org/uniprotkb/E1BLU2/entry#E1BLU2-1", "sequence": { "sequence": "MVVPGPVSRRAAAAATMLLRTARVPRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVVDLSMYQKVTSYCRSATLVGFTVGSVLGQILVSVASWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHVPPSCQGTNGIKIQNGGVATDTAASNHRPQWEDVESKIPLNREEPPVEEQESKPDRLLVLKVLWNDFLVCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEQVMPSRHAAIYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGELTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFFIYAGYFALIAVVFLANGTVSIMKKYRKQEDPESSSQETPS", "length": 496, "header": "tr|E1BLU2-1|E1BLU2_BOVIN Isoform 1 of Thiamine transporter 1 OS=Bos taurus OX=9913 GN=SLC19A2 PE=3 SV=1 CANONICAL=E1BLU2-1" }, "locus": { "chromosome": "16", "start_pos": 37128086, "end_pos": 37096402, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027006.5", "url": "https://www.ensembl.org/id/ENSBTAT00000027006.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027006.3", "url": "https://www.ensembl.org/id/ENSBTAP00000027006.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532860", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532860", "resource": "KEGG Pathway" }, { "id": "R-BTA-196819", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196819", "resource": "Reactome", "description": "Vitamin B1 (thiamin) metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XMI2-1", "protein_name": "Thiamine transporter 1", "gene_name": "SLC19A2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGPRGARPARSGPGCCWALPTGLLCAYGFFCSVRPSEPFLTRYLLGPHKNLSETQVFNEIYPVWTYCYLALLFPVFLATDYLRYKPVVLLQGLSLIITWFLLLYAQGLRAFQLLEFFYGMGTATDIAYYSYIYSVVDVDLYRKVTSYCRSATLVGYTVGSVCGQLLVSLAGWSLFSLNVISLTSVSVAFGTAWFLPMPRKSLFFHHAAAQPFSLEMKVMDCKNGAIVQDQPGVPRVPGWEDEVKMPLNREGHPAEKKEQKVDALKVLKDLWRDFLQCYSSRTMLCWSVWWALSTCGYFQVINYAQGLWEMVLPSHSTEIYNGGVEAASTLLGAVAVFVVGHIKTSWAMWGEVALALFSFLIAAAVYIMDTVHNIWVCYASYVVFRIIYMLLITIATFQIATNLSVERYALVFGVNTFIALALQTLLTLIVVDASGLGLDIFTQFMIYASYFAAISLVFLGSGLYSIMRAHRRQVQNRSPESC", "length": 483 }, "evidence": [ { "id": "E1BLU2", "url": "https://omabrowser.org/oma/group/E1BLU2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7F340-1", "protein_name": "Thiamine transporter 1", "gene_name": "slc19a2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEPWLYPTVLLCIYGFFSSHRPLEAFLMPFLMGPDKNLTETEVVSEIYPLWTYSYLALLFPVFLATDYLRYKPVIILQAASYVVTYALLVKAQGLQAMQIVEVFFGLATATEIAYYSYIYSVVEPSHYQMVTGFCRSVTLLGSAMGSLLGQILFSVADIALFYLCVITLVSFCIAFVAPWFLPMPSKSLFFHQSESSSQDEAVLETVNTSPLIEKPEDPESNKQPNANEKTTLKSNTSSSGLLDVLKMLWTDFLQCYSSSTLLAWSVWWALSTCGYLQVINYAQALWEDILTSKNYDIYNGYVETISTLLGAFAAFVVGYVKVSWAVWGELALCIFTVVIAVCVYLMYAVRNIWVCYTSYIIFRAVYMLLITIATYQIAANLSMKRYALVFGVNTFIALSLQMLLTVIVVDSAGLHLEISIQFLIYASYFAAVAVIFFIAGLYKLFRSRTSGGQNELSSAEA", "length": 463 }, "evidence": [ { "id": "E1BLU2", "url": "https://omabrowser.org/oma/group/E1BLU2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F6PV48-1", "protein_name": "Thiamine transporter 1", "gene_name": "SLC19A2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVPGPVSRRAAAAAATVLLRTARVPRECWFLPTALICAYGFFASLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVVDLSMYQKVTSYCRSATLVGFTVGSVLGQILVSVADWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHVPASQGMNGIKGSKPDRLLVLRVLWNDFLICYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEQVMPSRHASIYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGELTLSVFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAASLSMERYALVFGVNTFIALALQTLLTVIVVDASGLGLEITTQFFIYAGYFALIAVVFLANGAVSIMKKYRKQEDPESRSQVTTS", "length": 458 }, "evidence": [ { "id": "E1BLU2", "url": "https://omabrowser.org/oma/group/E1BLU2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O60779-1", "protein_name": "Thiamine transporter 1", "gene_name": "SLC19A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVNGIKVQNGGIVTDTPASNHLPGWEDIESKIPLNMEEPPVEEPEPKPDRLLVLKVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFALIAVVFLASGAVSVMKKCRKLEDPQSSSQVTTS", "length": 497 }, "evidence": [ { "id": "E1BLU2", "url": "https://omabrowser.org/oma/group/E1BLU2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q499Q0-1", "protein_name": "Thiamine transporter 1", "gene_name": "Slc19a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVPARVSRRAAAAAARMLLRTARVPRECWFLPTALLCAYGFFANLRPSEPFLTPYLLGPDKNLTERQVFNEIYPVWTYSYLLLLFPVFLATDYLRYKPVILLQGLSLIVTWFMLLYAQGLLAVQFLEFFYGIATATEIAYYSYIYTVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVVGWSLFSLNVLSLTCVSVAFAVAWFLPMPQKSLFFHHIPSSCHGVNGLKVQNGGITTDTPASNHLPGWEDIESKIPLNLDEPPVEEPEEPKPDRLRVFKVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEKVMPSQNAVIYNGGVEAVSTLLGASAVFAVGYIKLSWSTWGEVTLFLCSLLIAAAVYIMDTVENIWVCYASYVVFRIIYMVLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDARGLGLCIITQFLIYASYFAAISVVFLANGIVSIVKKCRKQEDPNSSPQATTS", "length": 498 }, "evidence": [ { "id": "E1BLU2", "url": "https://omabrowser.org/oma/group/E1BLU2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9EQN9-1", "protein_name": "Thiamine transporter 1", "gene_name": "Slc19a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDVPARVSRRAAAAAARMLLRTARVPRECWFLPTALLCAYGFFANLRPSEPFLTPYLLGPDKNLTERQVYNEIYPVWTYSYLLLLFPVFLATDYLRYKPVILLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYTVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVVGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSSCHGVNGLKVQNGGIVTDTPAANHLPGWEDIESKIPLNLDEPPVEEPEEPKPDRLRVFRVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEKVMPSQNADIYNGGVEAVSTLLGASAVFAVGYIKLSWSTWGEMTLFLCSLLIAAAVYVMDTVQSIWVCYASYVVFRIIYMVLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDARGLGLCITTQFLIYASYFAAISVVFLANGIVSIIKKCRKQEDPSSSPQASTS", "length": 498 }, "evidence": [ { "id": "E1BLU2", "url": "https://omabrowser.org/oma/group/E1BLU2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "vitamin transmembrane transporter activity", "id": "GO:0090482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090482", "evidence": [ { "database": "UniProtKB", "id": "E1BLU2", "url": "https://www.uniprot.org/uniprotkb/E1BLU2" } ], "pmid": "" }, { "name": "thiamine transmembrane transporter activity", "id": "GO:0015234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015234", "evidence": [ { "database": "UniProtKB", "id": "E1BLU2", "url": "https://www.uniprot.org/uniprotkb/E1BLU2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BLU2", "url": "https://www.uniprot.org/uniprotkb/E1BLU2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BLU2", "url": "https://www.uniprot.org/uniprotkb/E1BLU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "E1BLU2", "url": "https://www.uniprot.org/uniprotkb/E1BLU2" } ], "pmid": "" }, { "name": "thiamine diphosphate biosynthetic process", "id": "GO:0009229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009229", "evidence": [ { "database": "UniProtKB", "id": "E1BLU2", "url": "https://www.uniprot.org/uniprotkb/E1BLU2" } ], "pmid": "" }, { "name": "thiamine transport", "id": "GO:0015888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015888", "evidence": [ { "database": "UniProtKB", "id": "E1BLU2", "url": "https://www.uniprot.org/uniprotkb/E1BLU2" } ], "pmid": "" }, { "name": "pyridoxine transport", "id": "GO:0031923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031923", "evidence": [ { "database": "UniProtKB", "id": "E1BLU2", "url": "https://www.uniprot.org/uniprotkb/E1BLU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLU2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 496, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLU2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLU2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 413, "end_pos": 415 }, { "start_pos": 472, "end_pos": 474 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM23-1", "uniprot_ac": "E1BM23", "uniprot_id": "E1BM23_BOVIN", "mass": { "chemical_mass": 172269.0, "monoisotopic_mass": 172269.0 }, "refseq": { "ac": "XP_024837828", "name": "rho GTPase-activating protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837828" }, "gene_names": [ { "name": "ARHGAP5", "type": "recommended", "evidence": [ { "id": "E1BM23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM23" } ] }, { "name": "ARHGAP5", "type": "synonym", "evidence": [ { "id": "XP_024837828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837828" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 5", "type": "recommended", "evidence": [ { "id": "E1BM23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM23/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 5", "type": "synonym", "evidence": [ { "id": "E1BM23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM23/entry#names_and_taxonomy" } ] }, { "name": "p190-B", "type": "synonym", "evidence": [ { "id": "E1BM23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM23/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024837828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837828" } ] } ], "function": [ { "annotation": "GTPase-activating protein for Rho family members.", "evidence": [ { "database": "UniProtKB", "id": "E1BM23", "url": "https://www.uniprot.org/uniprotkb/E1BM23#function" }, { "database": "UniProtKB", "id": "ARBA00055851", "url": "https://www.uniprot.org/uniprotkb/ARBA00055851#function" }, { "database": "UniProtKB", "id": "A0AAA9SEE3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEE3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM23", "url": "https://www.uniprot.org/uniprotkb/E1BM23" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARHGAP5", "url": "https://www.uniprot.org/uniprotkb/E1BM23", "locus": { "chromosome": "21", "start_pos": 42582787, "end_pos": 42459887, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000027024", "url": "https://www.ensembl.org/id/ENSBTAG00000027024" } ] } } ], "crossref": [ { "id": "ENSBTAG00000027024", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000027024", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04373", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04373", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22220", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22220", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "788978", "url": "https://www.ncbi.nlm.nih.gov/gene/788978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:788978", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RIVKMRN", "url": "https://omabrowser.org/oma/group/RIVKMRN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM23", "url": "https://www.orthodb.org/?gene=E1BM23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46005", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46005", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46005:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46005:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01846", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01846", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16512", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16512", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19518", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19518", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013409", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9696273", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024837828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837828", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SEE3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SEE3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUL6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUL6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM23", "url": "https://www.uniprot.org/uniprotkb/E1BM23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM23-1", "url": "https://www.uniprot.org/uniprotkb/E1BM23-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAKNKEPRPPSYTISVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQSGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLNWSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLNFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPGGTYPRKFNETQIKQALRGVLESVKHNLDVVSPVPTNKDVSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEISAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDSTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVAPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDPSDNYSEPIDTIFKQKGYSDEIYVVPDDSQNRVIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKQKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNISLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKILDKAERLHALKEIVKKFHPVNYDVFRYIITHLNRVSQHNKVNLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAPAPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGII", "length": 1503, "header": "tr|E1BM23-1|E1BM23_BOVIN Isoform 1 of Rho GTPase-activating protein 5 OS=Bos taurus OX=9913 GN=ARHGAP5 PE=4 SV=3 CANONICAL=E1BM23-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SEE3-1", "url": "https://www.uniprot.org/uniprotkb/E1BM23/entry#A0AAA9SEE3-1", "sequence": { "sequence": "MMAKNKEPRPPSYTISVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQSGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLNWSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLNFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPGGTYPRKFNETQIKQALRGVLESVKHNLDVVSPVPTNKDVSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEISAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDSTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVAPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDPSDNYSEPIDTIFKQKGYSDEIYVVPDDSQNRVIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNISLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKILDKAERLHALKEIVKKFHPVNYDVFRYIITHLNRVSQHNKVNLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAPAPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGII", "length": 1502, "header": "tr|A0AAA9SEE3-1|E1BM23_BOVIN Computationally mapped isoform of Rho GTPase-activating protein 5 OS=Bos taurus OX=9913 GN=ARHGAP5 PE=4 SV=1 CANONICAL=E1BM23-1" }, "locus": { "chromosome": "21", "start_pos": 42581783, "end_pos": 42518880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125299.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125299.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080767.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080767.1" } ] } }, { "isoform_ac": "A0AAA9TUL6-1", "url": "https://www.uniprot.org/uniprotkb/E1BM23/entry#A0AAA9TUL6-1", "sequence": { "sequence": "MSLPPPPPGPLPLRRRRRRPTVLGLCTEGLYRVSGNKTDQDNIQKQFDQDHNISLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKILDKAERLHALKEIVKKFHPVNYDVFRYIITHLNRVSQHNKVNLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAPAPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGII", "length": 237, "header": "tr|A0AAA9TUL6-1|E1BM23_BOVIN Computationally mapped isoform of Rho GTPase-activating protein 5 OS=Bos taurus OX=9913 GN=ARHGAP5 PE=4 SV=1 CANONICAL=E1BM23-1" }, "locus": { "chromosome": "21", "start_pos": 42581783, "end_pos": 42506098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124041.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124041.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100264.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100264.1" } ] } }, { "isoform_ac": "E1BM23-1", "url": "https://www.uniprot.org/uniprotkb/E1BM23/entry#E1BM23-1", "sequence": { "sequence": "MMAKNKEPRPPSYTISVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQSGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLNWSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLNFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPGGTYPRKFNETQIKQALRGVLESVKHNLDVVSPVPTNKDVSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEISAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDSTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVAPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDPSDNYSEPIDTIFKQKGYSDEIYVVPDDSQNRVIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKQKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNISLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKILDKAERLHALKEIVKKFHPVNYDVFRYIITHLNRVSQHNKVNLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAPAPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGII", "length": 1503, "header": "tr|E1BM23-1|E1BM23_BOVIN Isoform 1 of Rho GTPase-activating protein 5 OS=Bos taurus OX=9913 GN=ARHGAP5 PE=4 SV=3 CANONICAL=E1BM23-1" }, "locus": { "chromosome": "21", "start_pos": 42581783, "end_pos": 42518880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038690.7", "url": "https://www.ensembl.org/id/ENSBTAT00000038690.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038500.5", "url": "https://www.ensembl.org/id/ENSBTAP00000038500.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1003, "start_aa": "Thr", "end_pos": 1003, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1003", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:788978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788978", "resource": "KEGG Pathway" }, { "id": "R-BTA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-BTA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-BTA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-BTA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-BTA-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" }, { "id": "R-BTA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-BTA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" }, { "id": "R-BTA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" }, { "id": "R-BTA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" }, { "id": "R-BTA-9696273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696273", "resource": "Reactome", "description": "RND1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7N9-1", "protein_name": "Rho GTPase-activating protein 5", "gene_name": "Arhgap5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMAKNKEPRPPSYTVSVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQNGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYISTLPRAFNTLLPDLEEIEHLNWLEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQYCTDIKVENLLANSLLHSDHNRSRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYILSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNESQIKQALRGVLESVKHNLDVVSPVPINKDVSEADLRIVMCAMCGDPFSVDIILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPVHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDSSDNYAEPLDTIFKQKGYPDEIYVVPDDSQNRIIKIRNSFVNNTQGDEENGFSDRTSKGHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFPTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQEVDDKKIKKKPHKVKEDKKKKKTKTFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLASMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAAPPTSNPGQLVESMVPLQLPPPLQPQLIQPQLQTDPLGII", "length": 1502 }, "evidence": [ { "id": "E1BM23", "url": "https://omabrowser.org/oma/group/E1BM23/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2QCH1-1", "protein_name": "Rho GTPase-activating protein 5", "gene_name": "Arhgap5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMAKNKEPRPPSYTVSVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQSGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYISTLPRAFNTLLPDLEEIEHLNWLEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQYCTDIKVEHLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYLLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNESQIKQALRGVLESVKHNLDVVSPVPINKDVSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPVHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQISRVPLPHPEDVDPSDNYSEPLDTIFKQKGYPDEIYVVPDDSQNRIIKIRNSFVNNTQGDEENGFSDRTLKGHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQEVDDKKMKKKTHKVKEDKKQKKKTKTFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKIERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETTNTVPPPPPSNPGQLVESMVPLQLPPPLQPQLIQPQLQTDPLGII", "length": 1503 }, "evidence": [ { "id": "E1BM23", "url": "https://omabrowser.org/oma/group/E1BM23/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XQ98-1", "protein_name": "Rho GTPase-activating protein 5", "gene_name": "ARHGAP5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMAKNKEPRPPSYAVSVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDVTQSGEDGIDCRIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLSIDGFLLCIDVSQGCNRKFDDQLKFVNNLYIQLSKSKKPIIIAATKCDECVDHYLREVQAFASNKKNLVVVETSARFNVNVETCFTALVQMMDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTKKAKNTFSKHIEQLKQEHIKKRKEEYINALPRALNTLLSNLDEIEHLSWSEALKLMEKRPDFHSCFVVLEKTPWDETDHIDKVNDRRIPFDLLTTLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVICFVMEDEAFKYITDADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHAVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQNCMDIKVEQLLANSLLQLDHGRSNLYHDSANIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYLLTQLWTSAFKPHGCFCVFNSIESLNFIGDCIAKIRAEASQIRRDKYMANLPFTLILANQRDSVSKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLEAVKHHFDVVSPVPTIKDLSEADLRIVMCAMCGDPFSVDLILSPFLESHSCSAAQAGQNNSVMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIESSYMSDSTRETTHTSEDVFSRSPRGSSLDYNYPDSEDDAEGPPPYSPIGDDVRLLPTPSDRSKYRLDLEGNEYPIHSTPLNCHDHERNHKVPPPIKPKPLVPRTNVKKLDPNLLKTIEAGIGKNPRKQPSRVPVAPPEDVDQSDNYAEPIDTIFKHKGFADDIYAVPDDSQNRIIKVRNSMPINAQGDEENGFSDRISKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKAKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKTKKKTQKVKEDKKQKKKVKTFNPPIRRNWESNYFGMPLQDLVTSEKPIPLFVEKCVQFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHSISLESMEVTVNAVAGALKAFFADLPDPLIPYSLHQELLEASKILDKTERLHELKEIVKKFHPVNYDVFKYVITHLNRVSQQYKTNFMTADNLSICFWPTLMRPDFENREFLSTTKIHQSIIETFIQQCQFFFYNGEIVEAPNPVACQPPPSNTVQMVEPMVPLQLPPPLQPQLIQPQLPADPLGII", "length": 1505 }, "evidence": [ { "id": "E1BM23", "url": "https://omabrowser.org/oma/group/E1BM23/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1R372-1", "protein_name": "Rho GTPase-activating protein 5", "gene_name": "arhgap5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAKNKETRPTYAVSVVGLSGTEKEKGNCGVGKSCLCNRYVRPSADCYYLEHTSVLSTIDFGGRVVNNDHFLYWGEVLHRGDDGVECRIQVIEQTEFIDDQTFLPHRSTNLQPYTKRAANTKLQSAEKLMYICTDQLGLEQDFDQKQMPDGKLNIDGFVLCIDISKGCNRKFDDQMKFVHSLYSQISKAKKPIIIAATKCDECVEQYLREVQTFVTGKKNLMLVETSARASVNVELCFNALTQQIDKTRGKPKIISYLEAYKSQRQLVASVSDKFEKLIVQTVRDYHTSWKIVSNKLKSHPDYEEYINLEGTKKARNTFSKHIEQLRQEHIKRRREDYLTSLPKIFNKLLNNLEEIETMSWTEAQSLMRSRHEFQYCFIELEHTPWYETDHLDKTDDRRVPFDILQTMQGERIYQNHVQHLISEKRRLEMKEKFKKTLERVHFISPGQPWEEVMCFVMEDEAYKYITESDRRDVYSRHQQEIVERAKEEFQEMLFEHAELFYDLDLNATPSYDKMSEIHAVLNEEPRYRALQKLATDRESLLLKHIGFVYHPTKETCLSGTACIDLKVEQVLANRLVQLDHGRSNIYYNSANIEKVNLCLVGREGLAQELANEIRAQSTDDEYTLDGKIYELDLLPVDVNSGMLLNHSWISTFKPHGFFCVFSSIESLNYIGDRVSRIRAEIAQSRRDRYSQPVPFILILANQRDSVCKNMPILRHQGQQLANKLQCTFVDIPTGTFPRKFNESQIKQALRAVLEGLKHNFDMMSPMPSIKDLSETDLRIVMCAMCGDPFSVDLILSPFLDSHSCSAGQPGQCNTLILDKIIGNGRRRIQVTVLSYHSSIGIRKDELVHGYILVYSAKRKSSMAMLRAFLAEVQDVIPVQLVAITDSQADFFENEAIKELMTEGEHIATEIAAKFTALYSLSQYHRQTEVFTPFFNEVLEKKSNIESSFMFDNSRDGTGTTEDVFPQSPHSHSPAYQYYPDSEDDGEGPPPYSPIGDDVQLLPNPSERKYRIDLEGNEYPIHSTPVGEHERNHKVPPPVKPKPNVLPKPNVKKLDPNLLRTIEAGMRTSRWTRGPMMGHSDDLEASDNYAEPADTLQHKSKGYSDDIYAVPEDAHSRSGKTRNSFGGLVVHVDEENGFDSMSKSQGGRRPSKYKHRSKILFSKTKAYHRRVHSDVSDDESGPATQKKKKGRGNRGSEEDPLLSPVDPWKGGIDNPAITSDPEQDERKTKKKKAPKTKEPKKPTRSTKTTKPLYPPTRRNWESNYFGVPLQNLVTPDRPIPLFVEKCVDYIERTGFTTEGLYRVCGNKTDQDNIQKQFDQDHSIDLIVMDVAVNAVAGALKAFFADLPDPLIPYSLHPELVEAAKIVDHYERLQVLKEIVRKFPPVNYEVFKYVITHLNRVSQHSKTTLMTADNLSICFWPTLMRPDFENKDTLSTTKLNQSVIESFIQQCQYFFYGGDMTEPSSAEGTPPPHGHGLESLLALQLPPPLQPQQIQHPLPPEPLI", "length": 1502 }, "evidence": [ { "id": "E1BM23", "url": "https://omabrowser.org/oma/group/E1BM23/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LD06-1", "protein_name": "Rho GTPase-activating protein 5", "gene_name": "ARHGAP5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMAKNKEPRPPSYTISVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQSGEDGVECRIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLSVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFAALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLNWSEALKLMEKRSDFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITETDSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLTSSLLQVDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYTLDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLNFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPVPTNKDVSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDPSDNYSEPIDTIFKQKGYSDEIYVVPDDSQNRIIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFPTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKLKKKTHKVKEDKKQKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNISLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPDLLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYIITHLNRVSQQNKVNLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGII", "length": 1503 }, "evidence": [ { "id": "E1BM23", "url": "https://omabrowser.org/oma/group/E1BM23/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97393-1", "protein_name": "Rho GTPase-activating protein 5", "gene_name": "Arhgap5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMAKNKEPRPPSYTVSVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQNGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYISTLPRAFNTLLPDLEEIEHLNWLEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQYCTDIKVENLLATSLLEMDHNRVRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYILSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMTNLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPTGTYPRKFNESQIKQALRGVLESVKHNLDVVSPVPINKDVSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPVHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDSSDNYVEPLDTIFKQKGYSDEIYVVPDDSQNRIIKIRNSFVNNTQGDEENGFSDRTSKGHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQEVDDKKIKKKTHKVKEDKKQKKKTKTFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLASMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERFHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAPPPTSNPGQLVESMVPLQLPPPLQPQLIQPQLQTDPLGII", "length": 1503 }, "evidence": [ { "id": "E1BM23", "url": "https://omabrowser.org/oma/group/E1BM23/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q13017-1", "protein_name": "Rho GTPase-activating protein 5", "gene_name": "ARHGAP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLNWSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKQKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGII", "length": 1502 }, "evidence": [ { "id": "E1BM23", "url": "https://omabrowser.org/oma/group/E1BM23/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VX32-1", "protein_name": "Rho GTPase-activating protein 190", "gene_name": "RhoGAPp190", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRQFNISVIGLSGTEKDRGQVGVGKSCLCNRFMRPMADDYFIDHISVLSQSDFSGRIVNNDHFLYWGDVRKTTEEGVEYQFNIIEQTEFMDDSTFQAFKVGKMDPYSKRCTATKVFSAEKLMYICKNQLGIEKEYEQKVMPDGRLSIDGFVVVFDVSPVPNRSVEKQVEFVQNVIATILKNKKPLVLVTTKNDDAYELYVREAEKISQRKDYKSTVQLIETSAHESINIDLAFLLLAQMIDKVKNRVKIISYQESAKSRKELLDTRSEAVTRLIRNQITDYHVLWSQGSKMLSQYREWNEFLNIFGHEAGQKLFRRHMKKLRDDHLNKKLHQYLDKFALALEYLLPDIGALNISDDDAWECARNYLQNHIEFEQYFFECPQASWTELVDMDEAEDEARIPFDVLETSEAETVFRNYLNSVQQDKKKIGWKQQFKMLLEESGFVTPGKQLSEVRVLFMGRECFEALSEHDCQQIYDIHQDDIIEKSKQNFVELLLEHAQYFLQFKNVDNITQEDVRQITDVIQEDSRYKMLDRLDQERRLMLVQHLRFIHCPIRDHCPFFYNCVDSLIEEVLSDKSASNHKTPSGGGWKSSGSGSDRTLNLLIVGSEHLASDLLNDIRICTGSKGEYIYENQTYYLNYRIANGDMEAFKAIDVYSSGLICVYSNQQSFETLKDNLERTLLCNLELEDKFENLPIVLVYQPQDLKENEVEYLRNEGMRLSEMLHCDFIDHTQNHQKYVYDILNIVILSLKLTEMKSYEPYPSNHTDLRILCCIFCGDQYDIENIVQPLVEESTLVKANEHSIIVDVFIGDAKRRVEFILSSYHGTSQYRDELIHGYIYFYSTKRRSSLANLSILAAQNANIPLQIIAVTESGGVNAFFNSDICQFLITEGNAVADRFKGSFMTFSADQYVKFAFYNPFLKTAWDNKYEVENLHVEESITLDSGEGTLENSVNQMPRPPPRHESYMLSNTLGTDGSGSENYEMAPTRSLNSLNEERDISLDEIYDDNEKPKHLHQKWLEDKSDGRRNMNKNLIWNNFSGSTHAYTTGRRHIDSNLNKIRPKGPSQTLKVGEAPSRNCPAMSSSTFTLPTQQPGKLNMKNFQLVSDAVAKMNFTGSGSGSGSGSGSGSTGLGLGLGSGSGCMGDSFLEPVDKDGKRYDHAQLDGEDEDSEELAEYEQIYENEDCTESDSCASSTERRVRQQNAYYKASKKPVAAKKQKKKKVAIPVQTPRVPPFGSYVSPPEIPLHYQRMAVGGSGPEKPEPCVPEFMKSDKSPEYSMVPELAGAGIFGAENLPEYNMNQAKCLKDFEKLEKRRIKEETARQRKLQEKEKEQEKKLKRKLKQNAKGLVESAEAQFGKLMITSEQGEIPIFLNKCVEFIEKEGLDSEGIYRVPGSRAHVDMLFQRFEEDTNTEIDALDIPVNAVATALKDFFSKRLPPLFSKDIIKELEEIAGSRGVGNSKLNVEVKTDRSCRLIALKSLLQKLPPINFAILKYIFQHFVHVSDNSKLNSMDSKNLAICWWPTLIPIDFTDMGHFEQLRPYLEDIVQTMIDQFPYLFCGKDAFVMV", "length": 1561 }, "evidence": [ { "id": "E1BM23", "url": "https://omabrowser.org/oma/group/E1BM23/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "E1BM23", "url": "https://www.uniprot.org/uniprotkb/E1BM23" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "E1BM23", "url": "https://www.uniprot.org/uniprotkb/E1BM23" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BM23", "url": "https://www.uniprot.org/uniprotkb/E1BM23" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BM23", "url": "https://www.uniprot.org/uniprotkb/E1BM23" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BM23", "url": "https://www.uniprot.org/uniprotkb/E1BM23" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BM23", "url": "https://www.uniprot.org/uniprotkb/E1BM23" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "E1BM23", "url": "https://www.uniprot.org/uniprotkb/E1BM23" } ], "pmid": "" }, { "name": "regulation of cell size", "id": "GO:0008361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008361", "evidence": [ { "database": "UniProtKB", "id": "E1BM23", "url": "https://www.uniprot.org/uniprotkb/E1BM23" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1090, "end_pos": 1092, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1128, "end_pos": 1130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1302, "end_pos": 1304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1318, "end_pos": 1320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1409, "end_pos": 1411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM23" }, { "id": "PS51676", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51676" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FF", "eco_id": "ECO_0000259", "start_pos": 267, "end_pos": 325, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM23" }, { "id": "PS51852", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51852" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PG1 pseudoGTPase", "eco_id": "ECO_0000259", "start_pos": 590, "end_pos": 763, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM23" }, { "id": "PS51853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PG2 pseudoGTPase", "eco_id": "ECO_0000259", "start_pos": 779, "end_pos": 944, "start_aa": "Arg", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM23" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 1263, "end_pos": 1450, "start_aa": "Met", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1003 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1090, "end_pos": 1092 }, { "start_pos": 1128, "end_pos": 1130 }, { "start_pos": 1302, "end_pos": 1304 }, { "start_pos": 1318, "end_pos": 1320 }, { "start_pos": 1409, "end_pos": 1411 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 507, "end_pos": 509 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 742, "end_pos": 744 }, { "start_pos": 813, "end_pos": 815 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLI8-1", "uniprot_ac": "E1BLI8", "uniprot_id": "E1BLI8_BOVIN", "mass": { "chemical_mass": 183086.0, "monoisotopic_mass": 183086.0 }, "refseq": {}, "gene_names": [ { "name": "MTCL2", "type": "recommended", "evidence": [ { "id": "E1BLI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLI8" } ] }, { "name": "SOGA1", "type": "recommended", "evidence": [ { "id": "E1BLI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLI8" } ] }, { "name": "SOGA1", "type": "synonym", "evidence": [ { "id": "E1BLI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLI8" } ] } ], "protein_names": [ { "name": "Microtubule crosslinking factor 2", "type": "synonym", "evidence": [ { "id": "E1BLI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLI8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLI8", "url": "https://www.uniprot.org/uniprotkb/E1BLI8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MTCL2", "url": "https://www.uniprot.org/uniprotkb/E1BLI8", "locus": { "chromosome": "13", "start_pos": 65837226, "end_pos": 65905791, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021669", "url": "https://www.ensembl.org/id/ENSBTAG00000021669" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021669", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021669", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR027881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BLI8", "url": "https://www.orthodb.org/?gene=E1BLI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15742:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15742:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SFR7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SFR7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLI8", "url": "https://www.uniprot.org/uniprotkb/E1BLI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLI8-1", "url": "https://www.uniprot.org/uniprotkb/E1BLI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVPAGEPPARGCGPPPAPAPERKKSHRAPSPARPKDVAGWSLAKGRRGPGPGAAAACSAASSARPDKKGRAVAPGARGAGTRVAGVRTGVRAKGRPRPGTGPRPPPPPPSLTDSSSEVSDCASEEARLLGLELALSSDAESAAGGPGGARTGQPPQPAQPAQQPPRPPASPEEPSVAASSVGSSRLPLSASLAFSDLTEEMLDCGPGGFVRELEELRSENDYLKDEIEELRAEMLEMRDVYMEEDVYQLQELRQQLDQASKTCRILQYRLRKAERRSLRAAQTGQVDGELIRGLEQDVKVSKDISVRLHKELEAVEKKRARLEEENEELRQRLIETELAKQVLQTELERPREHSLKKRGTRSLGKTDKKSSVQEDSADLKCQLHFAKEESALMCKKLTKLAKENDGMKEELLKYRSLYGDLDGALSAEELADAPHSRETELKVHLKLVEEEANLLSRRIVELEVENRGLRAEMDDMKDHGGGGGCGGPEARLAFSALGGGECGESLVELRRHLQFVEEEAELLRRSSAELEDQNKLLLSELAKYRSEHELDVTLSEDSCSVLSEPSQEELAAAKLQIGELSGKVKKLQYENRVLLSNLQRCDLASCQSTRPMLETDAEAGDSAQCVPASLAEAPGPAAARLCRAREAEALPGLREQAVLVSKAIDVLVADANGFSAGLRPYLDNECADFRLHEAPDNNSEGPRDTKLMHALLVRLSLLQQELNAFTRKADSVLGGPVKEPPEPFSTLPALSSQGPSKEILLAKDLGSDFQVQPPDLRDLPEWEPRIREAFHTSDLDSKSDPSRSFRPYRAEDNDSYASEIKELQLVLAEAHDSLRGLQEQLSQERQLRKEEAESFNQKVVQLKEDQQRALLRREFELQSLSLQRRLEQKFWSQEKNMLVQESQQFKHNFLLLFMKLRWFLKRWRQGKVLPSEGDDFLEVNSMKELYLLMEEEELNAQHSDNKTCAGDSWTQNTPNEYIKTLADMKVTLKELCWLLRDERRGLTELQQQFAKAKATWETERVELKSHTALMELKAGKGAGDRTGPDWKAALQREREEQQHLLAESYSAVMELTRQLQISEHNWAQEKLQLVERLQGEKQQVEQQLKELQNRLSQLQKASDPWVLKHSDLEKQDNSWKETRSEKIHDKEAVSEAELGGTGLKRTKSVSSMSEFESLLDCSPYLAGEASRGKKLPNSPAFAFVGAQPVDPEKGAPEQPGLSPRDCNRLGALGCPEPAGRQMQRSYTAPDKTGIRVYYSPPVARRLGVPVVHDREGKIIIEPGFLFTTAKPKESAEADGLAESSYSRWLCNFSRQRLDGGSGGGPSAAGPGFPAALHDFEMSGNMSDDMKEITNCVRQAMRSGSLERKVKSTSSQTVGVASVGTQTIRTVSVGLQTDPPRGSLHGKSWSPRGSSLVSVRSKQISSSLDKVHARIERPCCSPKYGSPKLQRRSVSKLDGAKDRSLWNLHQGKQNGSAWARSTTTRDSPVLRNINDGLSSLFSVVEHSGSTESVWKVGMSEARAKPEPPKYGIVQEFFRNVCGRAPSPTASTAGEEGSKKPEPLSPASYHQPEGMARILNKKVGKSGGSEEARLSVLPQVGKDGITRDGDGATVLPNEDAVCDCSTQSLASCFARPSRSAIRHSPSKCRLHPSESGWGGEERAAPPSE", "length": 1663, "header": "tr|E1BLI8-1|E1BLI8_BOVIN Isoform 1 of Microtubule crosslinking factor 2 OS=Bos taurus OX=9913 GN=MTCL2 PE=4 SV=3 CANONICAL=E1BLI8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SFR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BLI8/entry#A0AAA9SFR7-1", "sequence": { "sequence": "MEVPAGEPPARGCGPPPAPAPERKKSHRAPSPARPKDVAGWSLAKGRRGPGPGAAAACSAASSARPDKKGRAVAPGARGAGTRVAGVRTGVRAKGRPRPGTGPRPPPPPPSLTDSSSEVSDCASEEARLLGLELALSSDAESAAGGPGGARTGQPPQPAQPAQQPPRPPASPEEPSVAASSVGSSRLPLSASLAFSDLTEEMLDCGPGGFVRELEELRSENDYLKDEIEELRAEMLEMRDVYMEEDVYQLQELRQQLDQASKTCRILQYRLRKAERRSLRAAQTGQVDGELIRGLEQDVKVSKDISVRLHKELEAVEKKRARLEEENEELRQRLIETELAKQVLQTELERPREHSLKKRGTRSLGKTDKKSSVQEDSADLKCQLHFAKEESALMCKKLTKLAKENDGMKEELLKYRSLYGDLDGALSAEELADAPHSRETELKVHLKLVEEEANLLSRRIVELEVENRGLRAEMDDMKDHGGGGGCGGPEARLAFSALGGGECGESLVELRRHLQFVEEEAELLRRSSAELEDQNKLLLSELAKYRSEHELDVTLSEDSCSVLSEPSQEELAAAKLQIGELSGKVKKLQYENRVLLSNLQRCDLASCQSTRPMLETDAEAGDSAQCVPASLAEAPGPAAARLCRAREAEALPGLREQAVLVSKAIDVLVADANGFSAGLRPYLDNECADFRLHEAPDNNSEGPRDTKLMHALLVRLSLLQQELNAFTRKADSVLGGPVKEPPEPFSTLPALSSQGPSKEILLAKDLGSDFQVQPPDLRDLPEWEPRIREAFHTSDLDSKSDPSRSFRPYRAEDNDSYASEIKELQLVLAEAHDSLRGLQEQLSQERQLRKEEAESFNQKVVQLKEDQQRALLRREFELQSLSLQRRLEQKFWSQEKNMLVQESQQFKHNFLLLFMKLRWFLKRWRQGKVLPSEGDDFLEVNSMKELYLLMEEEELNAQHSDNKTCAGDSWTQNTPNEYIKTLADMKVTLKELCWLLRDERRGLTELQQQFAKAKATWETERVELKSHTALLQKASDPWVLKHSDLEKQDNSWKETRSEKIHDKEAVSEAELGGTGLKRTKSVSSMSEFESLLDCSPYLAGEASRGKKLPNSPAFAFVGAQPVDPEKGAPEQPGLSPRDCNRLGALGCPEPAGRQMQRSYTAPDKTGIRVYYSPPVARRLGVPVVHDREGKIIIEPGFLFTTAKPKESAEADGLAESSYSRWLCNFSRQRLDGGSGGGPSAAGPGFPAALHDFEMSGNMSDDMKEITNCVRQAMRSGSLERKVKSTSSQTVGVASVGTQTIRTVSVGLQTDPPRGSLHGKSWSPRGSSLVSVRSKQISSSLDKVHARIERPCCSPKYGSPKLQRRSVSKLDGAKDRSLWNLHQGKQNGSAWARSTTTRDSPVLRNINDGLSSLFSVVEHSGSTESVWKVGMSEARAKPEPPKYGIVQEFFRNVCGRAPSPTASTAGEEGSKKPEPLSPASYHQPEGMARILNKKVGKSGGSEEARLSVLPQVGKDGITRDGDGATVLPNEDAVCDCSTQSLASCFARPSRSAIRHSPSKCRLHPSESGWGGEERAAPPSE", 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"MEVPAGEPPARGCGPPPAPAPERKKSHRAPSPARPKDVAGWSLAKGRRGPGPGAAAACSAASSARPDKKGRAVAPGARGAGTRVAGVRTGVRAKGRPRPGTGPRPPPPPPSLTDSSSEVSDCASEEARLLGLELALSSDAESAAGGPGGARTGQPPQPAQPAQQPPRPPASPEEPSVAASSVGSSRLPLSASLAFSDLTEEMLDCGPGGFVRELEELRSENDYLKDEIEELRAEMLEMRDVYMEEDVYQLQELRQQLDQASKTCRILQYRLRKAERRSLRAAQTGQVDGELIRGLEQDVKVSKDISVRLHKELEAVEKKRARLEEENEELRQRLIETELAKQVLQTELERPREHSLKKRGTRSLGKTDKKSSVQEDSADLKCQLHFAKEESALMCKKLTKLAKENDGMKEELLKYRSLYGDLDGALSAEELADAPHSRETELKVHLKLVEEEANLLSRRIVELEVENRGLRAEMDDMKDHGGGGGCGGPEARLAFSALGGGECGESLVELRRHLQFVEEEAELLRRSSAELEDQNKLLLSELAKYRSEHELDVTLSEDSCSVLSEPSQEELAAAKLQIGELSGKVKKLQYENRVLLSNLQRCDLASCQSTRPMLETDAEAGDSAQCVPASLAEAPGPAAARLCRAREAEALPGLREQAVLVSKAIDVLVADANGFSAGLRPYLDNECADFRLHEAPDNNSEGPRDTKLMHALLVRLSLLQQELNAFTRKADSVLGGPVKEPPEPFSTLPALSSQGPSKEILLAKDLGSDFQVQPPDLRDLPEWEPRIREAFHTSDLDSKSDPSRSFRPYRAEDNDSYASEIKELQLVLAEAHDSLRGLQEQLSQERQLRKEEAESFNQKVVQLKEDQQRALLRREFELQSLSLQRRLEQKFWSQEKNMLVQESQQFKHNFLLLFMKLRWFLKRWRQGKVLPSEGDDFLEVNSMKELYLLMEEEELNAQHSDNKTCAGDSWTQNTPNEYIKTLADMKVTLKELCWLLRDERRGLTELQQQFAKAKATWETERVELKSHTALMELKAGKGAGDRTGPDWKAALQREREEQQHLLAESYSAVMELTRQLQISEHNWAQEKLQLVERLQGEKQQVEQQLKELQNRLSQLQKASDPWVLKHSDLEKQDNSWKETRSEKIHDKEAVSEAELGGTGLKRTKSVSSMSEFESLLDCSPYLAGEASRGKKLPNSPAFAFVGAQPVDPEKGAPEQPGLSPRDCNRLGALGCPEPAGRQMQRSYTAPDKTGIRVYYSPPVARRLGVPVVHDREGKIIIEPGFLFTTAKPKESAEADGLAESSYSRWLCNFSRQRLDGGSGGGPSAAGPGFPAALHDFEMSGNMSDDMKEITNCVRQAMRSGSLERKVKSTSSQTVGVASVGTQTIRTVSVGLQTDPPRGSLHGKSWSPRGSSLVSVRSKQISSSLDKVHARIERPCCSPKYGSPKLQRRSVSKLDGAKDRSLWNLHQGKQNGSAWARSTTTRDSPVLRNINDGLSSLFSVVEHSGSTESVWKVGMSEARAKPEPPKYGIVQEFFRNVCGRAPSPTASTAGEEGSKKPEPLSPASYHQPEGMARILNKKVGKSGGSEEARLSVLPQVGKDGITRDGDGATVLPNEDAVCDCSTQSLASCFARPSRSAIRHSPSKCRLHPSESGWGGEERAAPPSE", "length": 1663, "header": "tr|E1BLI8-1|E1BLI8_BOVIN Isoform 1 of Microtubule crosslinking factor 2 OS=Bos taurus OX=9913 GN=MTCL2 PE=4 SV=3 CANONICAL=E1BLI8-1" }, "locus": { "chromosome": "13", "start_pos": 65905592, "end_pos": 65838230, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028879.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028879.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028879.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028879.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1544, "start_aa": "Thr", "end_pos": 1544, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1544", "evidence": [ { "id": "", "database": 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}, { "name": "negative regulation of gluconeogenesis", "id": "GO:0045721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045721", "evidence": [ { "database": "UniProtKB", "id": "E1BLI8", "url": "https://www.uniprot.org/uniprotkb/E1BLI8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1308, "end_pos": 1310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1341, "end_pos": 1343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1470, "end_pos": 1472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 698, "end_pos": 700, "annotation": "n_glycosylation_sequon" }, { "start_pos": 814, "end_pos": 816, "annotation": "n_glycosylation_sequon" }, { "start_pos": 962, "end_pos": 964, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": 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"uniprot_canonical_ac": "E1BMT9-1", "uniprot_ac": "E1BMT9", "uniprot_id": "E1BMT9_BOVIN", "mass": { "chemical_mass": 34151.0, "monoisotopic_mass": 34151.0 }, "refseq": {}, "gene_names": [ { "name": "CLDN14", "type": "recommended", "evidence": [ { "id": "E1BMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMT9" } ] } ], "protein_names": [ { "name": "Claudin 14", "type": "synonym", "evidence": [ { "id": "E1BMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMT9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMT9", "url": "https://www.uniprot.org/uniprotkb/E1BMT9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CLDN14", "url": "https://www.uniprot.org/uniprotkb/E1BMT9", "locus": { "chromosome": "1", "start_pos": 148736201, "end_pos": 148800128, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030585", "url": "https://www.ensembl.org/id/ENSBTAG00000030585" } ] } } ], "crossref": [ { "id": "E1BMT9", "url": "https://alphafold.ebi.ac.uk/entry/E1BMT9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000030585", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030585", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "783180", "url": "https://www.ncbi.nlm.nih.gov/gene/783180", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:783180", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783180", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTAYKDN", "url": "https://omabrowser.org/oma/group/PTAYKDN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMT9", "url": "https://www.orthodb.org/?gene=E1BMT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SLD4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLD4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMT9", "url": "https://www.uniprot.org/uniprotkb/E1BMT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMT9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTCVPTQAHPKGHSNCLAASCSDALALKLPVSERGRSGGRQGPVESVGQAAWHPASSHSRWESGEAAGTARALHDSSRRPSERAAAGEAMANTAVQLLGFLLCFLGLVGTLITTVLPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPRDLQAARALMVVSCLLSGAACASAVVGMQCTRCAKGTPAKTACAAVGGALFLLAGLLCLVAVSWTTHDVVQNFYNPLLPSGMKFEIGQALYLGFIASALLLIGGTLLCLACQEEAPTRAPPRAAAAPTGAPAPAYRPPDAYKDNRAPSAVSASHSGYRLNDYV", "length": 326, "header": "tr|E1BMT9-1|E1BMT9_BOVIN Isoform 1 of Claudin 14 OS=Bos taurus OX=9913 GN=CLDN14 PE=3 SV=3 CANONICAL=E1BMT9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SLD4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMT9/entry#A0AAA9SLD4-1", "sequence": { "sequence": "MYEDSSRRPSERAAAGEAMANTAVQLLGFLLCFLGLVGTLITTVLPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPRDLQAARALMVVSCLLSGAACASAVVGMQCTRCAKGTPAKTACAAVGGALFLLAGLLCLVAVSWTTHDVVQNFYNPLLPSGMKFEIGQALYLGFIASALLLIGGTLLCLACQEEAPTRAPPRAAAAPTGAPAPAYRPPDAYKDNRAPSAVSASHSGYRLNDYV", "length": 255, "header": "tr|A0AAA9SLD4-1|E1BMT9_BOVIN Computationally mapped isoform of Claudin 14 OS=Bos taurus OX=9913 GN=CLDN14 PE=3 SV=1 CANONICAL=E1BMT9-1" }, "locus": { "chromosome": "1", "start_pos": 148789108, "end_pos": 148737205, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103731.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103731.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084738.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084738.1" } ] } }, { "isoform_ac": "E1BMT9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMT9/entry#E1BMT9-1", "sequence": { "sequence": "MTCVPTQAHPKGHSNCLAASCSDALALKLPVSERGRSGGRQGPVESVGQAAWHPASSHSRWESGEAAGTARALHDSSRRPSERAAAGEAMANTAVQLLGFLLCFLGLVGTLITTVLPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPRDLQAARALMVVSCLLSGAACASAVVGMQCTRCAKGTPAKTACAAVGGALFLLAGLLCLVAVSWTTHDVVQNFYNPLLPSGMKFEIGQALYLGFIASALLLIGGTLLCLACQEEAPTRAPPRAAAAPTGAPAPAYRPPDAYKDNRAPSAVSASHSGYRLNDYV", "length": 326, "header": "tr|E1BMT9-1|E1BMT9_BOVIN Isoform 1 of Claudin 14 OS=Bos taurus OX=9913 GN=CLDN14 PE=3 SV=3 CANONICAL=E1BMT9-1" }, "locus": { "chromosome": "1", "start_pos": 148757081, "end_pos": 148737205, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043204.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043204.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040792.4", "url": "https://www.ensembl.org/id/ENSBTAP00000040792.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 291, "start_aa": "Thr", "end_pos": 291, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr291", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:783180", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783180", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HXM8-1", "protein_name": "Claudin", "gene_name": "Cldn14", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPRDLQAARALMVISCLLSGTASACAVVGMKCTRCAKGTPAKTTFAVLGGALFLLAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEAPYRPYQAQSRAGATTTAAAPAYRPPAAYKDNRAPSVTSASHSGYRLNDYV", "length": 239 }, "evidence": [ { "id": "E1BMT9", "url": "https://omabrowser.org/oma/group/E1BMT9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95500-1", "protein_name": "Claudin-14", "gene_name": "CLDN14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV", "length": 239 }, "evidence": [ { "id": "E1BMT9", "url": "https://omabrowser.org/oma/group/E1BMT9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BJQ1-1", "protein_name": "Claudin", "gene_name": "Cldn14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPRDLQAARALMVISCLLSGMACACAVVGMKCTRCAKGTPAKTTFAVLGGALFLLAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEGPYRPYQPQSRAGATTTATAPAYRPPAAYKDNRAPSVTSAAHSGYRLNDYV", "length": 239 }, "evidence": [ { "id": "E1BMT9", "url": "https://omabrowser.org/oma/group/E1BMT9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Z0S3-1", "protein_name": "Claudin-14", "gene_name": "Cldn14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPRDLQAARALMVISCLLSGMACACAVVGMKCTRCAKGTPAKTTFAVLGGALFLLAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEAPYRPYPPQSRAGATTTATAPAYRPPAAYKDNRAPSVTSAAHSGYRLNDYV", "length": 239 }, "evidence": [ { "id": "E1BMT9", "url": "https://omabrowser.org/oma/group/E1BMT9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BMT9", "url": "https://www.uniprot.org/uniprotkb/E1BMT9" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "E1BMT9", "url": "https://www.uniprot.org/uniprotkb/E1BMT9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "E1BMT9", "url": "https://www.uniprot.org/uniprotkb/E1BMT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMT9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 326, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMT9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMT9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 291 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BME4-1", "uniprot_ac": "E1BME4", "uniprot_id": "E1BME4_BOVIN", "mass": { "chemical_mass": 110696.0, "monoisotopic_mass": 110696.0 }, "refseq": { "ac": "XP_024832483", "name": "cation channel sperm-associated auxiliary subunit epsilon isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832483" }, "gene_names": [ { "name": "CATSPERE", "type": "recommended", "evidence": [ { "id": "E1BME4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BME4" } ] }, { "name": "CATSPERE", "type": "synonym", "evidence": [ { "id": "XP_024832483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832483" } ] } ], "protein_names": [ { "name": "Catsper channel auxiliary subunit epsilon", "type": "synonym", "evidence": [ { "id": "E1BME4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BME4/entry#names_and_taxonomy" } ] }, { "name": "cation channel sperm-associated auxiliary subunit epsilon isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024832483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832483" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BME4", "url": "https://www.uniprot.org/uniprotkb/E1BME4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CATSPERE", "url": "https://www.uniprot.org/uniprotkb/E1BME4", "locus": { "chromosome": "16", "start_pos": 32580808, "end_pos": 32737166, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000044066", "url": "https://www.ensembl.org/id/ENSBTAG00000044066" } ] } } ], "crossref": [ { "id": "E1BME4", "url": "https://alphafold.ebi.ac.uk/entry/E1BME4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000044066", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044066", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "616691", "url": "https://www.ncbi.nlm.nih.gov/gene/616691", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616691", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616691", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR33722", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33722", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33722:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33722:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22844", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22844", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22849", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22849", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22850", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22850", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024832483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832483", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SQA9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQA9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9U2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9U2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BME4", "url": "https://www.uniprot.org/uniprotkb/E1BME4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BME4-1", "url": "https://www.uniprot.org/uniprotkb/E1BME4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSASGVAVLLSWLSCCGSALWRYYSNSPNYDIFSTRSIIKLEYEGTSFFEWSAPATCSIKNKRLPKTELRCSSPGMHAIKPIVSGPDLEEERYLSVDNSHICFLWYYKTISFVHNLTQIVVLWIYDPENADPSELLWNANEPSLNSIILSKQLAALGQMPFIYTILKRKVYFPQERIKDGKWYVSIPMTTRDVLKEVRGNQVAFQDCFIANSLFLLTFPLLTIPEIPGFLPISSPRGSQLIANWAACVPSFVVVVADMETFQTNDSFHTWTRIRVPPNILTEDERHNVSDVTLSRDGIFFLINGILYLKNYKTFTRLGSNANLPDGGIIGITSRKWCWINYLLKDKERRSNMAIWTENEVYLGYARLKFVKIVTTEKLKGLLHMSPTATLTIHNVEYTGHPLELALLLNYCIICNTSKTIYLVIHNEDTVQWVFQDFALNVSIDTFLIPYFLYSAMPELLLWDKHRIYYYYHNFTDTGVLQTTTEFGNLSRLSQNSIIHNVLMDYYGNIVVKMENNVMFYFKIKIKDAIKLHLWTNSTVKSLISFKPSGNMYLIYVFENGEIYPEEYPLQLEAQSITFKTKEKCPYMAFHNDIFHFSYLLDKGQNLSLWAQIVYPENIGLYIVVESYGPKILEIKDQIQYEIALGHCSKTTTITFSQNINYEAVDDYFKLQYENTGLLLVHVRPSELAKTCPISQKVFQISVGCDASKFIAVKGFTKKECLQHDFFYIIEQSYLRDRPSKPLRVKYNWDKYGCPLKVDFREKFHPLVQLYNDNGYVEDVEVNFIVWEIHGRDDYSFNNTMKKSGCLNEAQTWNSMIELNKHLPLEEVWGPENYKHCFSYAIGKPGDLTQPYEIINKSNYNHLVWPLDHSGMYVFRVKILDPNYSFCNLTTIFAIETFGVIPSPNAYMVAAFLFLLMLLFFSTLILSYFHYMRIYKKHIYEPLHKSKRKKKKN", "length": 952, "header": "tr|E1BME4-1|E1BME4_BOVIN Isoform 1 of Catsper channel auxiliary subunit epsilon OS=Bos taurus OX=9913 GN=CATSPERE PE=3 SV=4 CANONICAL=E1BME4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SQA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BME4/entry#A0AAA9SQA9-1", "sequence": { "sequence": "MHAIKPIVSGPDLEEERYLSVDNSHICFLWYYKTISFVHNLTQIVVLWIYDPENADPSELLWNANEPSLNSIILSKQLAALGQMPFIYTILKRKVYFPQERIKDGKWYVSIPMTTRDVLKEVRGNQVAFQDCFIANSLFLLTFPLLTIPEIPGFLPISSPRGSQLIANWAACVPSFVVVVADMETFQTNDSFHTWTRIRVPPNILTEDERHNVSDVTLSRDGIFFLINGILYLKNYKTFTRLGSNANLPDGGIIGITSRKWCWINYLLKDKERRSNMAIWTENEVYLGYARLKFVKIVTTEKLKGLLHMSPTATLTIHNVEYTGHPLELALLLNYCIICNTSKTIYLVIHNEDTVQWVFQDFALNVSIDTFLIPYFLYSAMPELLLWDKHRIYYYYHNFTDTGVLQTTTEFGNLSRLSQNSIIHNVLMDYYGNIVVKMENNVMFYFKIKIKDAIKLHLWTNSTVKSLISFKPSGNMYLIYVFENGEIYPEEYPLQLEAQSITFKTKEKCPYMAFHNDIFHFSYLLDKGQNLSLWAQIVYPENIGLYIVVESYGPKILEIKDQIQYEIALGHCSKTTTITFSQNINYEAVDDYFKLQYENTGLLLVHVRPSELAKTCPISQKVFQISVGCDASKFIAVKGFTKKECLQHDFFYIIEQSYLRDRPSKPLRVKYNWDKYGCPLKVDFREKFHPLVQLYNDNGYVEDVEVNFIVWEIHGRDDYSFNNTMKKSGCLNEAQTWNSMIELNKHLPLEEVWGPENYKHCFSYAIGKPGDLTQPYEIINKSNYNHLVWPLDHSGMYVFRVKILDPNYSFCNLTTIFAIETFGVIPSPNAYMVAAFLFLLMLLFFSTLILSYFHYMRIYKKHIYEPLHKSKRKKKKN", "length": 877, "header": "tr|A0AAA9SQA9-1|E1BME4_BOVIN Computationally mapped isoform of Catsper channel auxiliary subunit epsilon OS=Bos taurus OX=9913 GN=CATSPERE PE=3 SV=1 CANONICAL=E1BME4-1" }, "locus": { "chromosome": "16", "start_pos": 32713713, "end_pos": 32580905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104310.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104310.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085121.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085121.1" } ] } }, { "isoform_ac": "A0AAA9T9U2-1", "url": "https://www.uniprot.org/uniprotkb/E1BME4/entry#A0AAA9T9U2-1", "sequence": { "sequence": 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GN=CATSPERE PE=3 SV=1 CANONICAL=E1BME4-1" }, "locus": { "chromosome": "16", "start_pos": 32737166, "end_pos": 32589699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135459.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135459.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093641.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093641.1" } ] } }, { "isoform_ac": "E1BME4-1", "url": "https://www.uniprot.org/uniprotkb/E1BME4/entry#E1BME4-1", "sequence": { "sequence": "MSASGVAVLLSWLSCCGSALWRYYSNSPNYDIFSTRSIIKLEYEGTSFFEWSAPATCSIKNKRLPKTELRCSSPGMHAIKPIVSGPDLEEERYLSVDNSHICFLWYYKTISFVHNLTQIVVLWIYDPENADPSELLWNANEPSLNSIILSKQLAALGQMPFIYTILKRKVYFPQERIKDGKWYVSIPMTTRDVLKEVRGNQVAFQDCFIANSLFLLTFPLLTIPEIPGFLPISSPRGSQLIANWAACVPSFVVVVADMETFQTNDSFHTWTRIRVPPNILTEDERHNVSDVTLSRDGIFFLINGILYLKNYKTFTRLGSNANLPDGGIIGITSRKWCWINYLLKDKERRSNMAIWTENEVYLGYARLKFVKIVTTEKLKGLLHMSPTATLTIHNVEYTGHPLELALLLNYCIICNTSKTIYLVIHNEDTVQWVFQDFALNVSIDTFLIPYFLYSAMPELLLWDKHRIYYYYHNFTDTGVLQTTTEFGNLSRLSQNSIIHNVLMDYYGNIVVKMENNVMFYFKIKIKDAIKLHLWTNSTVKSLISFKPSGNMYLIYVFENGEIYPEEYPLQLEAQSITFKTKEKCPYMAFHNDIFHFSYLLDKGQNLSLWAQIVYPENIGLYIVVESYGPKILEIKDQIQYEIALGHCSKTTTITFSQNINYEAVDDYFKLQYENTGLLLVHVRPSELAKTCPISQKVFQISVGCDASKFIAVKGFTKKECLQHDFFYIIEQSYLRDRPSKPLRVKYNWDKYGCPLKVDFREKFHPLVQLYNDNGYVEDVEVNFIVWEIHGRDDYSFNNTMKKSGCLNEAQTWNSMIELNKHLPLEEVWGPENYKHCFSYAIGKPGDLTQPYEIINKSNYNHLVWPLDHSGMYVFRVKILDPNYSFCNLTTIFAIETFGVIPSPNAYMVAAFLFLLMLLFFSTLILSYFHYMRIYKKHIYEPLHKSKRKKKKN", "length": 952, "header": "tr|E1BME4-1|E1BME4_BOVIN Isoform 1 of Catsper channel auxiliary subunit epsilon OS=Bos taurus OX=9913 GN=CATSPERE PE=3 SV=4 CANONICAL=E1BME4-1" }, "locus": { "chromosome": "16", "start_pos": 32737166, "end_pos": 32580905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061263.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061263.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053235.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053235.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616691", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616691", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "CatSper complex", "id": "GO:0036128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036128", "evidence": [ { "database": "UniProtKB", "id": "E1BME4", "url": "https://www.uniprot.org/uniprotkb/E1BME4" } ], "pmid": "" }, { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "E1BME4", "url": "https://www.uniprot.org/uniprotkb/E1BME4" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "E1BME4", "url": "https://www.uniprot.org/uniprotkb/E1BME4" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "E1BME4", "url": "https://www.uniprot.org/uniprotkb/E1BME4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "E1BME4", "url": "https://www.uniprot.org/uniprotkb/E1BME4" } ], "pmid": "" }, { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "E1BME4", "url": "https://www.uniprot.org/uniprotkb/E1BME4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": 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"https://www.uniprot.org/uniprotkb/E1BME4" }, { "id": "PF22850", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CATSPERD/E C-terminal", "eco_id": "ECO_0000259", "start_pos": 732, "end_pos": 928, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BME4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BME4" }, { "id": "PF22849", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22849" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CATSPERE Ig-like", "eco_id": "ECO_0000259", "start_pos": 588, "end_pos": 698, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BME4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BME4" }, { "id": "PF22844", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22844" } ], 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"end_pos": 187, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 440, "end_pos": 442 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 605, "end_pos": 607 }, { "start_pos": 797, "end_pos": 799 }, { "start_pos": 855, "end_pos": 857 }, { "start_pos": 882, "end_pos": 884 }, { "start_pos": 887, "end_pos": 889 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"uniprot_ac": "E1BMN1", "uniprot_id": "E1BMN1_BOVIN", "mass": { "chemical_mass": 72284.0, "monoisotopic_mass": 72284.0 }, "refseq": { "ac": "XP_024837410", "name": "acid-sensing ion channel 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837410" }, "gene_names": [ { "name": "ASIC4", "type": "recommended", "evidence": [ { "id": "E1BMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN1" } ] }, { "name": "ASIC4", "type": "synonym", "evidence": [ { "id": "XP_024837410", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837410" } ] } ], "protein_names": [ { "name": "Acid sensing ion channel subunit family member 4", "type": "synonym", "evidence": [ { "id": "E1BMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN1/entry#names_and_taxonomy" } ] }, { "name": "acid-sensing ion channel 4", "type": "synonym", "evidence": [ { "id": "XP_024837410", "database": "RefSeq", "url": 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ENaC operates in epithelial tissues, where it mediates the electrodiffusion of sodium ions from extracellular fluid through the apical membrane of cells, with water following osmotically. It plays a key role in maintaining sodium homeostasis through electrogenic sodium reabsorption in the kidneys. 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"evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020537", "url": "https://www.ensembl.org/id/ENSBTAG00000020537" } ] } } ], "crossref": [ { "id": "E1BMN1", "url": "https://alphafold.ebi.ac.uk/entry/E1BMN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020537", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020537", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100848162", "url": "https://www.ncbi.nlm.nih.gov/gene/100848162", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100848162", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100848162", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR11690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11690:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024837410", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837410", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SWE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWE7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJ51", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJ51-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMN1", "url": "https://www.uniprot.org/uniprotkb/E1BMN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMN1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSGAAGAARRRGRAALAPSLTRSLAGTHAGADSCAGADKGSHKETIEERDKRQQRQQRQRHHQGCGAAGSGSDSPTSGPHPVPILFPACPEFRRAAAATAATPEGTGGCWPGRDRGRKAPAGPSIWGQMPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAAQGAAAPRDLATFASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFLYQAAGLARGYLTRPHLVVMDPAAPAPAAGFPAVTLCNINRFRHSALSDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRTGHQLADMLKSCNFSGHHCSASNFSVVYTRYGKCYTFNADPQSSLPSRAGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRAESGLREPELQGYSAYSVSACRLRCEKEAVLQRCHCRMVHMPGNETICPPNIYIECADHTLDSLGGGSGGPCFCPTPCNLTRYGKEISMVRIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQRAAYGLSALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDRLKRAWRRPKTPLRTSTGGISTLGLQELKEQSPCPSRGRAEGGGASSLLPNHHHPHGPPGSLFEDFAC", "length": 668, "header": "tr|E1BMN1-1|E1BMN1_BOVIN Isoform 1 of Acid sensing ion channel subunit family member 4 OS=Bos taurus OX=9913 GN=ASIC4 PE=3 SV=4 CANONICAL=E1BMN1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SWE7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMN1/entry#A0AAA9SWE7-1", "sequence": { "sequence": 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"url": "https://www.ensembl.org/id/ENSBTAT00000089747.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090798.2", "url": "https://www.ensembl.org/id/ENSBTAP00000090798.2" } ] } }, { "isoform_ac": "A0AAA9TJ51-1", "url": "https://www.uniprot.org/uniprotkb/E1BMN1/entry#A0AAA9TJ51-1", "sequence": { "sequence": "MLSGAAGAARRRGRAALAPSLTRSLAGTHAGADSCAGADKGSHKETIEERDKRQQRQQRQRHHQGCGAAGSGSDSPTSGPHPVPILFPACPEFRRAAAATAATPEGTGGCWPGRDRGRKAPAGPSIWGQMPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAAQGAAAPRDLATFASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFLYQAAGLARGYLTRPHLVVMDPAAPAPAAGFPAVTLCNINRFRHSALSDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRTGHQLADMLKSCNFSGHHCSASNFSVVYTRYGKCYTFNADPQSSLPSRAGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRAESGLREPELQGYSAYSVSACRLRCEKEAVLQRCHCRMVHMPDSLGGGSGGPCFCPTPCNLTRYGKEISMVRIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQRAAYGLSALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDRLKRAWRRPKTPLRTSTGGISTLGLQELKEQSPCPSRGRAEGGGASSLLPNHHHPHGPPGSLFEDFAC", "length": 649, "header": "tr|A0AAA9TJ51-1|E1BMN1_BOVIN Computationally mapped isoform of Acid sensing ion channel subunit family member 4 OS=Bos taurus OX=9913 GN=ASIC4 PE=3 SV=1 CANONICAL=E1BMN1-1" }, "locus": { "chromosome": "2", "start_pos": 107465982, "end_pos": 107443938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132918.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132918.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098475.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098475.1" } ] } }, { "isoform_ac": "E1BMN1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMN1/entry#E1BMN1-1", "sequence": { "sequence": "MLSGAAGAARRRGRAALAPSLTRSLAGTHAGADSCAGADKGSHKETIEERDKRQQRQQRQRHHQGCGAAGSGSDSPTSGPHPVPILFPACPEFRRAAAATAATPEGTGGCWPGRDRGRKAPAGPSIWGQMPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAAQGAAAPRDLATFASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFLYQAAGLARGYLTRPHLVVMDPAAPAPAAGFPAVTLCNINRFRHSALSDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRTGHQLADMLKSCNFSGHHCSASNFSVVYTRYGKCYTFNADPQSSLPSRAGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRAESGLREPELQGYSAYSVSACRLRCEKEAVLQRCHCRMVHMPGNETICPPNIYIECADHTLDSLGGGSGGPCFCPTPCNLTRYGKEISMVRIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQRAAYGLSALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDRLKRAWRRPKTPLRTSTGGISTLGLQELKEQSPCPSRGRAEGGGASSLLPNHHHPHGPPGSLFEDFAC", "length": 668, "header": "tr|E1BMN1-1|E1BMN1_BOVIN Isoform 1 of Acid sensing ion channel subunit family member 4 OS=Bos taurus OX=9913 GN=ASIC4 PE=3 SV=4 CANONICAL=E1BMN1-1" }, "locus": { "chromosome": "2", "start_pos": 107465982, "end_pos": 107443938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027364.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027364.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027364.7", "url": "https://www.ensembl.org/id/ENSBTAP00000027364.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 502, "start_aa": "Thr", "end_pos": 502, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr502", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100848162", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100848162", "resource": "KEGG Pathway" }, { "id": "R-BTA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BMN1", "url": "https://www.uniprot.org/uniprotkb/E1BMN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "E1BMN1", "url": "https://www.uniprot.org/uniprotkb/E1BMN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "E1BMN1", "url": "https://www.uniprot.org/uniprotkb/E1BMN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMN1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 668, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMN1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMN1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 502 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 267, "end_pos": 269 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 505, "end_pos": 507 }, { "start_pos": 534, "end_pos": 536 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OTX2", "url": "https://www.uniprot.org/uniprotkb/E1BNP1", "locus": { "chromosome": "10", "start_pos": 69215622, "end_pos": 69224652, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014741", "url": "https://www.ensembl.org/id/ENSBTAG00000014741" } ] } } ], "crossref": [ { "id": "E1BNP1", "url": "https://alphafold.ebi.ac.uk/entry/E1BNP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014741", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014741", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538953", "url": "https://www.ncbi.nlm.nih.gov/gene/538953", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", 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"Enzyme and Pathway" ] }, { "id": "QTNISMM", "url": "https://omabrowser.org/oma/group/QTNISMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNP1", "url": "https://www.orthodb.org/?gene=E1BNP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45793:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45793:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180130", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180130", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T066", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T066", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T066-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T066-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T586", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T586", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T586-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T586-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTP9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTP9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNP1-1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPAISSSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGTTLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL", "length": 289, "header": "tr|E1BNP1-1|E1BNP1_BOVIN Isoform 1 of Orthodenticle homeobox 2 OS=Bos taurus OX=9913 GN=OTX2 PE=3 SV=1 CANONICAL=E1BNP1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T066-1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1/entry#A0AAA9T066-1", "sequence": { "sequence": "MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPAISSSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGTTLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL", "length": 297, "header": "tr|A0AAA9T066-1|E1BNP1_BOVIN Computationally mapped isoform of Orthodenticle homeobox 2 OS=Bos taurus OX=9913 GN=OTX2 PE=3 SV=1 CANONICAL=E1BNP1-1" }, "locus": { "chromosome": "10", "start_pos": 69219670, "end_pos": 69216072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120053.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120053.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092137.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092137.1" } ] } }, { "isoform_ac": "A0AAA9T586-1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1/entry#A0AAA9T586-1", "sequence": { "sequence": "MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL", "length": 168, "header": "tr|A0AAA9T586-1|E1BNP1_BOVIN Computationally mapped isoform of Orthodenticle homeobox 2 OS=Bos taurus OX=9913 GN=OTX2 PE=3 SV=1 CANONICAL=E1BNP1-1" }, "locus": { "chromosome": "10", "start_pos": 69219670, "end_pos": 69216072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124428.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124428.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092987.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092987.1" } ] } }, { "isoform_ac": "A0AAA9TTP9-1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1/entry#A0AAA9TTP9-1", "sequence": { "sequence": "MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGMV", "length": 35, "header": "tr|A0AAA9TTP9-1|E1BNP1_BOVIN Computationally mapped isoform of Orthodenticle homeobox 2 OS=Bos taurus OX=9913 GN=OTX2 PE=3 SV=1 CANONICAL=E1BNP1-1" }, "locus": { "chromosome": "10", "start_pos": 69219670, "end_pos": 69216682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114079.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114079.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099915.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099915.1" } ] } }, { "isoform_ac": "E1BNP1-1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1/entry#E1BNP1-1", "sequence": { "sequence": "MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPAISSSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGTTLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL", "length": 289, "header": "tr|E1BNP1-1|E1BNP1_BOVIN Isoform 1 of Orthodenticle homeobox 2 OS=Bos taurus OX=9913 GN=OTX2 PE=3 SV=1 CANONICAL=E1BNP1-1" }, "locus": { "chromosome": "10", "start_pos": 69219670, "end_pos": 69216072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019616.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019616.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019616.4", "url": "https://www.ensembl.org/id/ENSBTAP00000019616.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538953", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538953", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M039-1", "protein_name": "Homeobox protein OTX2 isoform X1", "gene_name": "Otx2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL", "length": 297 }, "evidence": [ { "id": "E1BNP1", "url": "https://omabrowser.org/oma/group/E1BNP1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SSM3-1", "protein_name": "Orthodenticle homeobox 2", "gene_name": "OTX2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPAISSSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGTTLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL", "length": 297 }, "evidence": [ { "id": "E1BNP1", "url": "https://omabrowser.org/oma/group/E1BNP1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P32243-1", "protein_name": "Homeobox protein OTX2", "gene_name": "OTX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL", "length": 289 }, "evidence": [ { "id": "E1BNP1", "url": "https://omabrowser.org/oma/group/E1BNP1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P80206-1", "protein_name": "Homeobox protein OTX2", "gene_name": "Otx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKSSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL", "length": 289 }, "evidence": [ { "id": "E1BNP1", "url": "https://omabrowser.org/oma/group/E1BNP1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64201-1", "protein_name": "Homeobox protein OTX2", "gene_name": "Otx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGAS", "length": 70 }, "evidence": [ { "id": "E1BNP1", "url": "https://omabrowser.org/oma/group/E1BNP1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91981-1", "protein_name": "Homeobox protein OTX2", "gene_name": "otx2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSYLKQPPYTVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKSSPAREASSESGASGQFTPPSSTSVPAISTTTAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLTGPGSTLSPMSSNAVTSHLNQSPASLPTQGYGASGLGFNSTADCLDYKDQASSWKLNFNADCLDYKDQTSSWKFQVL", "length": 289 }, "evidence": [ { "id": "E1BNP1", "url": "https://omabrowser.org/oma/group/E1BNP1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "dopaminergic neuron differentiation", "id": "GO:0071542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071542", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "positive regulation of embryonic development", "id": "GO:0040019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040019", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "primitive streak formation", "id": "GO:0090009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090009", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" }, { "name": "positive regulation of gastrulation", "id": "GO:2000543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000543", "evidence": [ { "database": "UniProtKB", "id": "E1BNP1", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNP1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 289, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNP1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNP1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNP1" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 96, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 }, { "start_pos": 251, "end_pos": 253 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNF0-1", "uniprot_ac": "E1BNF0", "uniprot_id": "E1BNF0_BOVIN", "mass": { "chemical_mass": 128474.0, "monoisotopic_mass": 128474.0 }, "refseq": {}, "gene_names": [ { "name": "RBM33", "type": "recommended", "evidence": [ { "id": "E1BNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNF0" } ] } ], "protein_names": [ { "name": "RNA-binding protein 33", "type": "recommended", "evidence": [ { "id": "E1BNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNF0/entry#names_and_taxonomy" } ] }, { "name": "Proline-rich protein 8", "type": "synonym", "evidence": [ { "id": "E1BNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNF0/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 33", "type": "synonym", "evidence": [ { "id": "E1BNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNF0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "RNA reader protein, which recognizes and binds specific RNAs, thereby regulating RNA metabolic processes, such as mRNA export, mRNA stability and/or translation. Binds a subset of intronless RNAs containing GC-rich elements, such as NORAD, and promotes their nuclear export by recruiting target RNAs to components of the NXF1-NXT1 RNA export machinery. Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, promoting their demethylation by ALKBH5. Acts as an molecular adapter, which (1) promotes ALKBH5 recruitment to m6A-containing transcripts and (2) activates ALKBH5 demethylase activity by recruiting SENP1, leading to ALKBH5 deSUMOylation and subsequent activation.", "evidence": [ { "database": "UniProtKB", "id": "E1BNF0", "url": "https://www.uniprot.org/uniprotkb/E1BNF0#function" }, { "database": "UniProtKB", "id": "ARBA00054794", "url": "https://www.uniprot.org/uniprotkb/ARBA00054794#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNF0", "url": "https://www.uniprot.org/uniprotkb/E1BNF0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RBM33", "url": "https://www.uniprot.org/uniprotkb/E1BNF0", "locus": { "chromosome": "4", "start_pos": 117463803, "end_pos": 117358074, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010243", "url": "https://www.ensembl.org/id/ENSBTAG00000010243" } ] } } ], "crossref": [ { "id": "E1BNF0", "url": "https://alphafold.ebi.ac.uk/entry/E1BNF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010243", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010243", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BNF0", "url": "https://www.orthodb.org/?gene=E1BNF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22014", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22014", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22014:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22014:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0AAA9T3X2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3X2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3X2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNF0", "url": "https://www.uniprot.org/uniprotkb/E1BNF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNF0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAALGAGGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELDDDLLGEDLLSGKKNQSDLSDEELNDDLLQSDNEDEENFCTQDVTISLTATSDMVTSFEMSDTNDQSAEQESEYEQGEDELVYHKSDGSELYAHEYPEEGQYEGHDAELTEDHIEYVEEPEEEQLYNDEVLDIEINEPLDEFTGGMETLELQKDIKEESDEEDDDDEESGRLRFKTERKEGTIIRLSDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYGSRRGGRRGGASLCRGVGDQRRESSERGRAKDHRPALLPTQPPVVTYSPRLIPPPQPQPPPPPPPPPPPQQPIRSLFQQQQLQPLLPLQHPHHPSPPQGMHMPPQIEAPRVMMTPPPVTPQQPKNIHINPHFKGAVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQERDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLSSGHPVPTPSPLPFTQPGPAFSQQGQQPVFPRERPVRPALQPPGPVGLLHFSQPGSAATRPFIPPRQPFLPGPGQPFLPTHTQPSLQGPLHPPLPPPHQPQPQPQPQPPLQPPLQPPLQPPPPHQPPHQPQQHHHHLSVPPPPLMPVAQPQFRPHMPAAQPQPSSSRMQCPQRPGLRHNTTSQNVTKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSTSRCSSTPAAQVKPIMSTSPAPRPGVGPRNTQGKAEGRAKPLSPVGQPKEEAKTGAEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQQQQLCAPPAPAAPGEPTPTPPPANGNPLLPFPGPPVRPNVKNRLLVKNQDAAVANVPPKTSGFVPSGAHTQYPGQQMKPLRHLRQARTIPQSPAQHKALQAKPADAEGPPPPSQAARAASLQGRPPEAKPGAKRTVMHRASSGGGDGPHVSSKVRVIKLSGGQGGESDGFFHPEGQPQRIPQPPEVRQQPARKVTLTKGALQQPQHPALGAHMHAAGPPGIKSIQGIHPAKKVLVHGRGRGLAGAMGRGRLMPNKQNLRVVECKPQPCVVSVEGLSSSTTDAQLKSLLTSVGPIQSLQMLPQQRKAIAKFKEPAHALAFQQKFHRHMIDLSHINVALIVE", "length": 1169, "header": "tr|E1BNF0-1|E1BNF0_BOVIN Isoform 1 of RNA-binding protein 33 OS=Bos taurus OX=9913 GN=RBM33 PE=4 SV=4 CANONICAL=E1BNF0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T3X2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNF0/entry#A0AAA9T3X2-1", "sequence": { "sequence": "MAAALGAGGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELDDDLLGEDLLSGKKNQSDLSDEELNDDLLQSDNEDEENFCTQDVTISLTATSDMVTSFEMSDTNDQSAEQESEYEQGEDELVYHKSDGSELYAHEYPEEGQYEGHDAELTEDHIEYVEEPEEEQLYNDEVLDIEINEPLDEFTDEEYLQACGQQGMKEQEDCVAEEELDEITDSQVDPETEEGGMETLELQKDIKEESDEEDDDDEESGRLRFKTERKEGTIIRLSDVTRERRNIPETLGNFFTCLTFSCIPISTSCIVLLR", "length": 305, "header": "tr|A0AAA9T3X2-1|E1BNF0_BOVIN Computationally mapped isoform of RNA-binding protein 33 OS=Bos taurus OX=9913 GN=RBM33 PE=4 SV=2 CANONICAL=E1BNF0-1" }, "locus": { "chromosome": "4", "start_pos": 117399425, "end_pos": 117358292, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093483.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093483.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092485.2", "url": "https://www.ensembl.org/id/ENSBTAP00000092485.2" } ] } }, { "isoform_ac": "E1BNF0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNF0/entry#E1BNF0-1", "sequence": { "sequence": "MAAALGAGGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELDDDLLGEDLLSGKKNQSDLSDEELNDDLLQSDNEDEENFCTQDVTISLTATSDMVTSFEMSDTNDQSAEQESEYEQGEDELVYHKSDGSELYAHEYPEEGQYEGHDAELTEDHIEYVEEPEEEQLYNDEVLDIEINEPLDEFTGGMETLELQKDIKEESDEEDDDDEESGRLRFKTERKEGTIIRLSDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYGSRRGGRRGGASLCRGVGDQRRESSERGRAKDHRPALLPTQPPVVTYSPRLIPPPQPQPPPPPPPPPPPQQPIRSLFQQQQLQPLLPLQHPHHPSPPQGMHMPPQIEAPRVMMTPPPVTPQQPKNIHINPHFKGAVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQERDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLSSGHPVPTPSPLPFTQPGPAFSQQGQQPVFPRERPVRPALQPPGPVGLLHFSQPGSAATRPFIPPRQPFLPGPGQPFLPTHTQPSLQGPLHPPLPPPHQPQPQPQPQPPLQPPLQPPLQPPPPHQPPHQPQQHHHHLSVPPPPLMPVAQPQFRPHMPAAQPQPSSSRMQCPQRPGLRHNTTSQNVTKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSTSRCSSTPAAQVKPIMSTSPAPRPGVGPRNTQGKAEGRAKPLSPVGQPKEEAKTGAEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQQQQLCAPPAPAAPGEPTPTPPPANGNPLLPFPGPPVRPNVKNRLLVKNQDAAVANVPPKTSGFVPSGAHTQYPGQQMKPLRHLRQARTIPQSPAQHKALQAKPADAEGPPPPSQAARAASLQGRPPEAKPGAKRTVMHRASSGGGDGPHVSSKVRVIKLSGGQGGESDGFFHPEGQPQRIPQPPEVRQQPARKVTLTKGALQQPQHPALGAHMHAAGPPGIKSIQGIHPAKKVLVHGRGRGLAGAMGRGRLMPNKQNLRVVECKPQPCVVSVEGLSSSTTDAQLKSLLTSVGPIQSLQMLPQQRKAIAKFKEPAHALAFQQKFHRHMIDLSHINVALIVE", "length": 1169, "header": "tr|E1BNF0-1|E1BNF0_BOVIN Isoform 1 of RNA-binding protein 33 OS=Bos taurus OX=9913 GN=RBM33 PE=4 SV=4 CANONICAL=E1BNF0-1" }, "locus": { "chromosome": "4", "start_pos": 117462799, "end_pos": 117358292, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000060950.5", "url": "https://www.ensembl.org/id/ENSBTAT00000060950.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053550.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053550.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 509, "start_aa": "Thr", "end_pos": 509, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr509", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 846, "start_aa": "Thr", "end_pos": 846, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr846", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 848, "start_aa": "Thr", "end_pos": 848, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr848", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BNF0", "url": "https://www.uniprot.org/uniprotkb/E1BNF0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BNF0", "url": "https://www.uniprot.org/uniprotkb/E1BNF0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of mRNA stability", "id": "GO:0043488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043488", "evidence": [ { "database": "UniProtKB", "id": "E1BNF0", "url": "https://www.uniprot.org/uniprotkb/E1BNF0" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "E1BNF0", "url": "https://www.uniprot.org/uniprotkb/E1BNF0" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "E1BNF0", "url": "https://www.uniprot.org/uniprotkb/E1BNF0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N6-methyladenosine-containing RNA reader activity", "id": "GO:1990247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990247", "evidence": [ { "database": "UniProtKB", "id": "E1BNF0", "url": "https://www.uniprot.org/uniprotkb/E1BNF0" } ], "pmid": "" }, { "name": "lncRNA binding", "id": "GO:0106222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106222", "evidence": [ { "database": "UniProtKB", "id": "E1BNF0", "url": "https://www.uniprot.org/uniprotkb/E1BNF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNF0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1169, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNF0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNF0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNF0" }, { "id": "SM00360", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00360" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 1098, "end_pos": 1165, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 509, 846, 848 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 58, "end_pos": 60 }, { "start_pos": 680, "end_pos": 682 }, { "start_pos": 685, "end_pos": 687 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNL1-1", "uniprot_ac": "E1BNL1", "uniprot_id": "E1BNL1_BOVIN", "mass": { "chemical_mass": 158661.0, "monoisotopic_mass": 158661.0 }, "refseq": { "ac": "XP_010816569", "name": "ATP-binding cassette sub-family C member 10 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816569" }, "gene_names": [ { "name": "ABCC10", "type": "recommended", "evidence": [ { "id": "E1BNL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ] }, { "name": "ABCC10", "type": "synonym", "evidence": [ { "id": "XP_010816569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816569" } ] } ], "protein_names": [ { "name": "ATP-binding cassette sub-family C member 10", "type": "recommended", "evidence": [ { "id": "E1BNL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNL1/entry#names_and_taxonomy" } ] }, { "name": "7.6.2.2", "type": "synonym", "evidence": [ { "id": "E1BNL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNL1/entry#names_and_taxonomy" } ] }, { "name": "7.6.2.3", "type": "synonym", "evidence": [ { "id": "E1BNL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNL1/entry#names_and_taxonomy" } ] }, { "name": "ATP-binding cassette sub-family C member 10 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_010816569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816569" } ] }, { "name": "Multidrug resistance-associated protein 7", "type": "synonym", "evidence": [ { "id": "E1BNL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNL1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ABCC10", "url": "https://www.uniprot.org/uniprotkb/E1BNL1", "locus": { "chromosome": "23", "start_pos": 17009685, "end_pos": 16988544, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005842", "url": "https://www.ensembl.org/id/ENSBTAG00000005842" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005842", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005842", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03244", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03244", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18598", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18598", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18605", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18605", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "508399", "url": "https://www.ncbi.nlm.nih.gov/gene/508399", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:508399", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508399", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYAWPSQ", "url": "https://omabrowser.org/oma/group/PYAWPSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNL1", "url": "https://www.orthodb.org/?gene=E1BNL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF330", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF330", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-382556", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-382556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010816569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816569", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "85015", "url": "https://www.rhea-db.org/rhea/85015", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9T645", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T645", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T645-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T645-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERFLARLCGTSALQPLPVWEGDTTGHCFTQLVLSALPHALLAVLSACHWGHPRYPDYTPRCSPGWRLRLTASVLLAVFPLLDLLPVILPPGAGPGPTGLEVLAGGVAAMAWISHSLALWVLVHTPYGHSRGPLALALAAFLPAPALVLTLLWHCQRGTLLPPLLAGPLSRLCLLILQLAALLAYGLGWAVPGQPREPWAHEPLLSEGQEPEVAEDGESWLSRFSYAWLAPLLARGARGELRQPQDTCRLPHRLHPTYLARVFQAQWQEGARLWRTLHGAFGHCYLALGLLKLVGTMLGFSGPLLLSLLVGFLEEGREPLSHGLLYALGLTGGAVLGAVLQNQYGYEVRKVALQARGAVLNILYRKALQLGPRRPPAGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLHQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGMRVIKFFGWEQALGTRVEACRARELGRLRVIKYLDAACVYLWAALPVVISIVIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQCFLDLPNHDPQAYYSPDPPTEPSTALELHEALFSWDPVGTSQETFISHLEVKKGMLVGIVGKVGCGKSSLLAAITGELHRLRGQVAVWGLSKGFGLATQEPWIQFATIRDNILFGKTFDAQLYKEVLEACALDEDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKELYLLDDPLAAVDADVATHLLHRCILGALSHTTRLLCTHRTEYLERADMVLLLEAGRLVRAGPPSEILPLVQAAPRAWAEDGQESDRATASSMENPKKTKEGLEVEESASGQLRQEESKKEGAVAFHVYRAYWRAVGWGMALAILFSLLLMQATRNAADWWLSHWISELKAAKNSSQEALAPTRLGSMGPLSAQLLLFSPGSLCTSVFPLPKAAPNGSSDLRFYLTVYATIAGVNSLCTLLRAVLFAAGTLQAAATLHRRLLGRVLMAPVTFFDSTPTGRVLNRFSSDVACADDSLPFILNILLANAAGLLGLLAVLGFSLPWLLLLLPPLSIIYYRVQSHYRASSRELRRLGSLSLSPLYTHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFAASATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTEAMLVSVERLEEYSCDLPQEPRGQRPQLGISWLSQGSVEFQNVVLVYRPGLPNALDGVTFRVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGMDTSQLELAELRSQLAIIPQEPFLFSGTVRENLDPRGLYEDGALWQALEQCHLSEAIESMGGLDGELGEGGRRLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTISKRFANKTVLTIAHRLPPGSLECSVSGNMQPLP", "length": 1458, "header": "tr|E1BNL1-1|E1BNL1_BOVIN Isoform 1 of ATP-binding cassette sub-family C member 10 OS=Bos taurus OX=9913 GN=ABCC10 PE=3 SV=2 CANONICAL=E1BNL1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T645-1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1/entry#A0AAA9T645-1", "sequence": { "sequence": "MERFLARLCGTSALQPLPVWEGDTTGHCFTQLVLSALPHALLAVLSACHWGHPRYPDYTPRCSPGWRLRLTASVLLAVFPLLDLLPVILPPGAGPGPTGLEVLAGGVAAMAWISHSLALWVLVHTPYGHSRGPLALALAAFLPAPALVLTLLWHCQRGTLLPPLLAGPLSRLCLLILQLAALLAYGLGWAVPGQPREPWAHEPLLSEGQEPEVAEDGESWLSRFSYAWLAPLLARGARGELRQPQDTCRLPHRLHPTYLARVFQAQWQEGARLWRTLHGAFGHCYLALGLLKLVGTMLGFSGPLLLSLLVGFLEEGREPLSHGLLYALGLTGGAVLGAVLQNQYGYEVRKVALQARGAVLNILYRKALQLGPRRPPAGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLHQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGMRVIKFFGWEQALGTRVEACRARELGRLRVIKYLDAACVYLWAALPVVISIVIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQCFLDLPNHDPQAYYSPDPPTEPSTALELHEALFSWDPVGTSQETFISHLEVKKGMLVGIVGKVGCGKSSLLAAITGELHRLRGQVAVWGLSKGFGLATQEPWIQFATIRDNILFGKTFDAQLYKEVLEACALDEDLSEKELYLLDDPLAAVDADVATHLLHRCILGALSHTTRLLCTHRTEYLERADMVLLLEAGRLVRAGPPSEILPLVQAAPRAWAEDGQESDRATASSMENPKKTKEGLEVEESASGQLRQEESKKEGAVAFHVYRAYWRAVGWGMALAILFSLLLMQATRNAADWWLSHWISELKAAKNSSQEALAPTRLGSMGPLSAQLLLFSPGSLCTSVFPLPKAAPNGSSDLRFYLTVYATIAGVNSLCTLLRAVLFAAGTLQAAATLHRRLLGRVLMAPVTFFDSTPTGRVLNRFSSDVACADDSLPFILNILLANAAGLLGLLAVLGFSLPWLLLLLPPLSIIYYRVQSHYRASSRELRRLGSLSLSPLYTHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFAASATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTEAMLVSVERLEEYSCDLPQEPRGQRPQLGISWLSQGSVEFQNVVLVYRPGLPNALDGVTFRVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGMDTSQLELAELRSQLAIIPQEPFLFSGTVRENLDPRGLYEDGALWQALEQCHLSEAIESMGGLDGELGEGGRRLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTISKRFANKTVLTIAHRLNTILNSDRVLVLHAGRVAELGSPAALCTQPHSLFQQLLQSSPRGVRSSP", "length": 1457, "header": "tr|A0AAA9T645-1|E1BNL1_BOVIN Computationally mapped isoform of ATP-binding cassette sub-family C member 10 OS=Bos taurus OX=9913 GN=ABCC10 PE=3 SV=1 CANONICAL=E1BNL1-1" }, "locus": { "chromosome": "23", "start_pos": 17008681, "end_pos": 16988987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124313.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124313.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091243.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091243.1" } ] } }, { "isoform_ac": "E1BNL1-1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1/entry#E1BNL1-1", "sequence": { "sequence": "MERFLARLCGTSALQPLPVWEGDTTGHCFTQLVLSALPHALLAVLSACHWGHPRYPDYTPRCSPGWRLRLTASVLLAVFPLLDLLPVILPPGAGPGPTGLEVLAGGVAAMAWISHSLALWVLVHTPYGHSRGPLALALAAFLPAPALVLTLLWHCQRGTLLPPLLAGPLSRLCLLILQLAALLAYGLGWAVPGQPREPWAHEPLLSEGQEPEVAEDGESWLSRFSYAWLAPLLARGARGELRQPQDTCRLPHRLHPTYLARVFQAQWQEGARLWRTLHGAFGHCYLALGLLKLVGTMLGFSGPLLLSLLVGFLEEGREPLSHGLLYALGLTGGAVLGAVLQNQYGYEVRKVALQARGAVLNILYRKALQLGPRRPPAGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLHQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGMRVIKFFGWEQALGTRVEACRARELGRLRVIKYLDAACVYLWAALPVVISIVIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQCFLDLPNHDPQAYYSPDPPTEPSTALELHEALFSWDPVGTSQETFISHLEVKKGMLVGIVGKVGCGKSSLLAAITGELHRLRGQVAVWGLSKGFGLATQEPWIQFATIRDNILFGKTFDAQLYKEVLEACALDEDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKELYLLDDPLAAVDADVATHLLHRCILGALSHTTRLLCTHRTEYLERADMVLLLEAGRLVRAGPPSEILPLVQAAPRAWAEDGQESDRATASSMENPKKTKEGLEVEESASGQLRQEESKKEGAVAFHVYRAYWRAVGWGMALAILFSLLLMQATRNAADWWLSHWISELKAAKNSSQEALAPTRLGSMGPLSAQLLLFSPGSLCTSVFPLPKAAPNGSSDLRFYLTVYATIAGVNSLCTLLRAVLFAAGTLQAAATLHRRLLGRVLMAPVTFFDSTPTGRVLNRFSSDVACADDSLPFILNILLANAAGLLGLLAVLGFSLPWLLLLLPPLSIIYYRVQSHYRASSRELRRLGSLSLSPLYTHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFAASATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTEAMLVSVERLEEYSCDLPQEPRGQRPQLGISWLSQGSVEFQNVVLVYRPGLPNALDGVTFRVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGMDTSQLELAELRSQLAIIPQEPFLFSGTVRENLDPRGLYEDGALWQALEQCHLSEAIESMGGLDGELGEGGRRLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTISKRFANKTVLTIAHRLPPGSLECSVSGNMQPLP", "length": 1458, "header": "tr|E1BNL1-1|E1BNL1_BOVIN Isoform 1 of ATP-binding cassette sub-family C member 10 OS=Bos taurus OX=9913 GN=ABCC10 PE=3 SV=2 CANONICAL=E1BNL1-1" }, "locus": { "chromosome": "23", "start_pos": 17008393, "end_pos": 16988987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007685.7", "url": "https://www.ensembl.org/id/ENSBTAT00000007685.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007685.5", "url": "https://www.ensembl.org/id/ENSBTAP00000007685.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:508399", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508399", "resource": "KEGG Pathway" }, { "id": "R-BTA-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZX04-1", "protein_name": "ATP-binding cassette sub-family C member 10", "gene_name": "Abcc10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSVLPHALLAVLSACHLGTPRTNNIIQPFNPGWRLRLTASFLLSVFPLLDLLPVVLPPVSHPGPLWLEVLAGCVTAVAWFTHSLALWALVHSPHGHSRGPLALALAAFLPTPALVLTLLWHCQRGTFLPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPREPWTHDPFLSPESQEREVAEDGESWLSRFSYAWLAPLLARGVRGELRQPQDTCRLPRRLHPAYLARAFQAHWKEGAQLWRALYGAFGCCYIALGLLKMVGTMLGFSGPLLLSLLVGFLEEGQEPLSHGLLYVLGLASGSVISAVLQNQYGYEVRKVTLQARVAVLSILYRKTLKLGPSRPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYEQVGVAFLAGLVLALLLVPVNKVIATRIMANNQEMLRHKDARVKLMTELLSGIRVLKFFRWEQALGDRVKACRTQELGRLRVIKYLDAACVYLWAALPVVICIVIFITYVLLGHQLTATKVFTALALVHMLILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPTEPSTVLELHEALFSWDPTGTSQKTFISHLQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVSDLSKGFGLATQEPWIQCATIRDNVLFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKTLYLLDDPLAAVDADVANHLLHRCILGVLGHTTRLLCTHRTEYLERADLVLLMEAGRLVRAGPPSEILPLVQAAPTALADKEQVTDSGQSPSVHNLEKTTEELDVAQNTSGRLVQEESKSEGAVALHVYRAYWRAMGSGLATAILISLLLMQATRNGADWWLAHWLSQLKAGRNSSEERPASSSPRSMGFFSPRLLLFSPGNLLSIPLHKATSNGSSDVHFYLTVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFIYYGVQRRYRASFRELRRLGSLTLSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDIPQEPHGQPPQSPHQRVSWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPSAGQVLLDGVDTSQLELAELRSQLAVIPQEPFLFSGTVRENLDPQGLHEDRALWQALEQCHLSEVAMAIGGLDGELGERGRDLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICRRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFRQLLQSSQQGAHSLPAAC", "length": 1495 }, "evidence": [ { "id": "E1BNL1", "url": "https://omabrowser.org/oma/group/E1BNL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RRK8-1", "protein_name": "ATP-binding cassette sub-family C member 10", "gene_name": "ABCC10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERFLAQLCGTSALQPLPVWEGDTTGHCFTQLVLSALPHALLAVLSACHWGNPRNPDWIPHRSPGWRLRLTASFLLSIFPLLDLLPVALPPGAGPGPVGLEVLAGGMAAVAWISHSMALWVLSHSPHGRSRGPLALALAAFLPAPALVLTLLWHCQRGTLLPPLLPGPLSRLCLIILQLAVLLAYGLGWAVPGKPREPWAQEPLLPEGQEAEVAEDGESWLSRFSYAWLAPLLARGARRELRQPQDTCRLPRRLHPTYLAHIFQAHWQEGARLWRALYGAFGRCYLALGLLKLVGTMLGFSGPLLLSLLVGFLEEGQEPLSNGLLYALGLAGGAVLGAVLQNQYGYEVQKVTLQARGAVLNILYRKALHLGPRRPPVGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLHQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGIRVIKFFGWEQALGARVEACRARELGRLWVIKYLDAACVYLWAALPVVISIVIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQRFLDLPNHNPQAYYSPDPPTDPTAALELHEALFSWDPAGTSQETFISHLQVKKGMLVGIVGKVGCGKSSLLAAISGELHRLRGQVAVWELSRGFGLATQEPWIQFATIRDNILFGKMFDAQLYKEVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKELYLLDDPLAAVDADVASHLLHKCILGALGHTTRLLCTHRTEYLEKADVVLLMENGRLVQAGPPSEILPLVQAVPKAWAEDGQESDPATAQSVQTPEKTKEGLDVEGSTSDRLLQDESKKEGAVAFHVYRAYWRAMGPGLALAILFSLLLMQATRNAADWWLSHWISQLKAAKNNSQEAPAPSSLNSEGLLSAQLLLFSPGSLYTSVLPLPKAAPNGSSDIRFYLTVYATIAGVNSFCTLLRAVLFAAGTLRAAATLHRRLLCRVLMAPVTFFDSTPTGRVLNRFSSDVACADDSLPFILNILLANTAGLLGLLVVLGSGLPWLLLLLPPLSAIYYRVQRHYRASSRELRRLGSLTLSPLYTHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASSATMQWLDIRLQLMGATVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTETMLVSVERLEEYSCDLPQEPRGQWPQLGISWLSQGSVEFQDVVLVYRPGLPNALDGVTFRVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGVDTSQLELAELRSQLAIIPQEPFLFSGTVRENLDPRGLYEDRALWQALEQCHLSGVLRSMGGLDAELGEGGRSLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICQRFANKTVLTIAHRLNTILNSDRVLVLQAGRVAELDSPAALRSQPHSLFQQLLQSSQQRARPLP", "length": 1490 }, "evidence": [ { "id": "E1BNL1", "url": "https://omabrowser.org/oma/group/E1BNL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5T3U5-1", "protein_name": "ATP-binding cassette sub-family C member 10", "gene_name": "ABCC10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERLLAQLCGSSAAWPLPLWEGDTTGHCFTQLVLSALPHALLAVLSACYLGTPRSPDYILPCSPGWRLRLAASFLLSVFPLLDLLPVALPPGAGPGPIGLEVLAGCVAAVAWISHSLALWVLAHSPHGHSRGPLALALVALLPAPALVLTVLWHCQRGTLLPPLLPGPMARLCLLILQLAALLAYALGWAAPGGPREPWAQEPLLPEDQEPEVAEDGESWLSRFSYAWLAPLLARGACGELRQPQDICRLPHRLQPTYLARVFQAHWQEGARLWRALYGAFGRCYLALGLLKLVGTMLGFSGPLLLSLLVGFLEEGQEPLSHGLLYALGLAGGAVLGAVLQNQYGYEVYKVTLQARGAVLNILYCKALQLGPSRPPTGEALNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGIRVIKFCGWEQALGARVEACRARELGRLRVIKYLDAACVYLWAALPVVISIVIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQLFLDLPNHNPQAYYSPDPPAEPSTVLELHGALFSWDPVGTSLETFISHLEVKKGMLVGIVGKVGCGKSSLLAAIAGELHRLRGHVAVRGLSKGFGLATQEPWIQFATIRDNILFGKTFDAQLYKEVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKELYLLDDPLAAVDADVANHLLHRCILGMLSYTTRLLCTHRTEYLERADAVLLMEAGRLIRAGPPSEILPLVQAVPKAWAENGQESDSATAQSVQNPEKTKEGLEEEQSTSGRLLQEESKKEGAVALHVYQAYWKAVGQGLALAILFSLLLMQATRNAADWWLSHWISQLKAENSSQEAQPSTSPASMGLFSPQLLLFSPGNLYIPVFPLPKAAPNGSSDIRFYLTVYATIAGVNSLCTLLRAVLFAAGTLQAAATLHRRLLHRVLMAPVTFFNATPTGRILNRFSSDVACADDSLPFILNILLANAAGLLGLLAVLGSGLPWLLLLLPPLSIMYYHVQRHYRASSRELRRLGSLTLSPLYSHLADTLAGLSVLRATGATYRFEEENLRLLELNQRCQFATSATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTEAMLVSVERLEEYTCDLPQEPQGQPLQLGTGWLTQGGVEFQDVVLAYRPGLPNALDGVTFCVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIPQEPFLFSGTVRENLDPQGLHKDRALWQALKQCHLSEVITSMGGLDGELGEGGRSLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPATLRNQPHSLFQQLLQSSQQGVPASLGGP", "length": 1492 }, "evidence": [ { "id": "E1BNL1", "url": "https://omabrowser.org/oma/group/E1BNL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R4P9-1", "protein_name": "ATP-binding cassette sub-family C member 10", "gene_name": "Abcc10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSALPHALLAVLSACHLGTPRTTNHSPALNPGWRLRLAASFLLSIFPLLDLLPVVLPPGSRPGPLWLEVLAGCVTAVAWFTHSLALWALVHSPHGRSRGPLALALAAFLPTPALVLTLLWHCQRGTFLPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPQEPWTHDPFLSSESQETEVAEDGESWLSRFSYAWLAPLLARGVRGELQQPRDTCRLPRRLHPAFLARVFQAHWKEGAQLWRALYRAFGCCYLALGLLKMVGTMLGFSGPLLLSLLVGFLEEGQEPLSHGLLYVLGLAGGTVISAVLQNQYGYEVRKVTLQARVAVLSTLYRKALKLGPSRPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYQQVGMAFLAGLVLALLLVPVNKVIATRIMASNQEMLRHKDARVKLMTELLSGIRVIKFFRWEQALGDRVKACRTKELGRLRVIKYLDAACVYLWAALPVVICITIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPAEPSTALELHEALFSWDPIGASQKTFISHLQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVSELSKGFGLATQEPWIQCATIRDNILFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKALYLLDDPLAAVDADVANHLLHRCILGVLSHTTRLLCTHRTEYLERADVVLLMEAGQLVRTGPPSEILPLVQAVPTAWAEKEQVATSGQSPSVCDLERTTEEELEVEQSTCGCLVQEESKSEGAVALHVYRAYWRAMGSGLAAAILVSLLLMQATRNGADWWLAHWLSQLKAGRNGSREDPASCSPGSTALFSPRLLLFSPGNLYTPLLSTPLHKAASNGTADVHFYLIVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFVYYSVQGYYRASFRELRRLGSLTWSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDVPQEPHSQPLQSPHQQRISWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPNAGRVLLDNVDTSQLELAELRSQLAVIPQEPFLFSGTIRENLDPQGLHEDRALWQALEQCHLSEVAVAMGGLDGELGERGQNLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFQQLLQSSQQGAHSGPSGC", "length": 1501 }, "evidence": [ { "id": "E1BNL1", "url": "https://omabrowser.org/oma/group/E1BNL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8ST87-1", "protein_name": "ABC transporter C family member 10", "gene_name": "abcC10", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKEIELDRPEEKKKKVKKEKKIGYGGKKSPEENSNFLSNLTFSWADGFVIHCFRNVLQLSHLWDLASYDKSEYLAKKIAKSWEIEIQKPKPSYLRAGFRAFGKLQLLSIFLYAISVGIQFVGPEILGRMVTFVVESKLGTSTEDPNMGYYYALIMFGTAMIGSFCTYHANRISFRTGDRLRSIIVLDVYKKAIKLSNSARSDTSPGQIVNLMSNDAQRMVEVFGMFNNGALALPQIIICLALLYKKIGWPTFVGLGLMLAAIPFNGMAAKKLTETRKYLVSLSDSRVKATNEILQAIKIIKLYAWEDSFAKKVIEHRNNEIKLLFSYSRYRTILIVIISALPTAAAILVISSYYGHEKSLDASRIFSALSYLNLLRLPLGFLPIIIALGIQMQIAGKRVTDFLLLPEMKDIQQIDNPSLPNGVYMKNSTTTWNKLKEDSFGLKNINFEATGTSLTMVVGSVGSGKSTLVQAMLGELEIIDGEIGIKGSIAYVPQQAWIINATLKENIIFGKELDEERYQKVLEVCALKRDIELFPQGDSVEIGERGINLSGGQKQRVSIARAVYSDADVYILDDPLSAVDSHVGKHLFHKCFKGILSSKTVILVANQLNYLPFADNTVVLKSGEIVERGTYYELINSKLEFSSILEKYGVDENVISKKDDIDEDEDEDQDTIEKVEIDLNKDEKSQPKSKSSNTDGTLISEEESEQGAVAGKVYWKYVTAGGGLLFLVSMIFFLLETGSKTFSDWWLSHWQTESSERMESILLGEEPTGLTDDQNLGIYIGLGMAAVFISVCKNFIYYEYSVYASRAIHHELFNALLKKPMYFFDQTPIGRIINRFTRDLDGIDNLIATSISTFLTLMLTVIATIILVSIIVPFLLIPLAPISIIFFFLQYFYRYTSRGLQRIEAITRSPIFNHFSETLNGVVSIRAYKKQQENILINQKRLDDNNNCYLTLQAMNRWLGLRLDFLANLITFFACIFITIDKDTISPANVGLALGYALSLTGNLNYAALQAADTETKMNSVERISQYIRGAVEAPQIIDDCRPSPDWPINGSIKFDNLVMRYREGLDPVLKGITCEIKAKEKIGIVGRTGAGKSSIVLALFRLIEASEGSISIDGENIAKFGLKDLRRNLAIIPQDPVLFSGTLRENLDPFNERSEEDLFSTIEDIQMSAVVKSLEGGLDSKVTENGENFSVGQRQLIVLARALLRKPKILVLDEATASVDGQSDSLIQATIRNKFSNCTILTIAHRLNTIMDSDRIMVLDAGKISEFDEPWTLLQNQNGLLTWLVDETGPQNAIYLRKLAEAKKNGIDINEIMPIDNETTPKDNINTPPPPPQ", "length": 1334 }, "evidence": [ { "id": "E1BNL1", "url": "https://omabrowser.org/oma/group/E1BNL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VLP5-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG7806", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSVVDWGDFAWNWTQFCPTGLKPFANETNDLLPCFQEILLQLPVYTLFAAISAYNFGNQSRHVVRNGLQLRMLSIRTFLAMVLALLPVAKVFAFHQQGVELFAADLLVVSAECIMWVVHSGFLLTARQYGELSHRGSLLINVVWLTVVVLDAVWLRTSRHFSWWPWSLATLVCDLLFGVTLIPKGSAVYSSLPRSGVSAREDEGLLSQRYTYFQFDLNESHLGHAQDEANLGSRFLFHWVQPLILKGVAGKLRKIEDLFDLPDALNITRLSEKLHLALSQSQSLWRALHRCFGVEFYLIGILRLIADLSGFAGPLLLGGLLRQDHADPNQVYYYALGLFGSTLLSAVCATHFDWRMAMVSMKMRVGVVNSIYRKALEARGLKESKPDLLNLMSTDTDRIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPINRWLAKRIGIFSSGLMTAKDARLSATTETMQGAKQIKINAWEDIFITKIRGLRQEELRFLSKRKYLDAMCVYFWATTPVLMCLLTFGVSVLMGNPLIASTTYTSVALLYMLIGPLNAFPWVLNGLIEAWVSIKRVQQLMDVPNLDYSSYYNPIMRGSGGSGAGDDAPLDAPKASVLQMKCASFCHDSDEQTSPTPFRMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCVQELTTGFGYVPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQILGGDLVGVGENGRTLSGGQRARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCILRLLKHKTRIVVTRNIQLFFHANQILQVKDGQLLPSEYMTQSIELSLDEDADDEQEPTVRRRSVELSNQYDKKSLDSLLLEELREYGHLSGNVFTCYWKAVTSPLAFTVLLSVVLMQLTRNLSDAWLAYWVTETTLDPHKNDTSLDHILMRPTVGNETESGHTTKFYLSIFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNRFSSDTNTVDDSLPFILNILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHASRDIKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAAQQWLALRLQLLGTLLVGGAGLLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERIDQYLQLEEEQNASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERIGIVGRTGAGKTSVLAALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPRHGFYDSEIWHAIKNSAAATLLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDDESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIFYGMLLAQDIDPGEFIRSN", "length": 1487 }, "evidence": [ { "id": "E1BNL1", "url": "https://omabrowser.org/oma/group/E1BNL1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ], "pmid": "" }, { "name": "ABC-type glutathione S-conjugate transporter activity", "id": "GO:0015431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015431", "evidence": [ { "database": "UniProtKB", "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ], "pmid": "" }, { "name": "organic anion transport", "id": "GO:0015711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015711", "evidence": [ { "database": "UniProtKB", "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ], "pmid": "" }, { "name": "leukotriene metabolic process", "id": "GO:0006691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006691", "evidence": [ { "database": "UniProtKB", "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ], "pmid": "" }, { "name": "leukotriene transport", "id": "GO:0071716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071716", "evidence": [ { "database": "UniProtKB", "id": "E1BNL1", "url": "https://www.uniprot.org/uniprotkb/E1BNL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1431, "end_pos": 1433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 918, "end_pos": 920, "annotation": "n_glycosylation_sequon" }, { "start_pos": 960, "end_pos": 962, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "85015", "name": "", "equation": "5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine(in) + ATP + H2O = 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BNL1-1" ], "evidence": [ { "id": "85015", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/85015" } ] }, { "id": "R-BTA-1454916", "name": "The ABCC family mediates organic anion transport", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-1454930" ], "output_participant_list": [ "R-ALL-1454919" ], "enzyme_list": [ "Q8HXQ5-1", "F1MZD4-1", "F1N3Y6-1", "A0A3Q1NLJ8-1", "F1MN01-1", "E1BNL1-1" ], "evidence": [ { "id": "R-BTA-1454916", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1454916" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1454919", "participant_name": "organic anion [extracellular region]", "crossref": [ { "id": "25696", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1454930", "participant_name": "organic anion [cytosol]", "crossref": [ { "id": "25696", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1NLJ8", "gene_name": "ABCC2", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NLJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLJ8" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NLJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLJ8" } ] }, { "ec_number": "7.6.2.3", "activity": "", "evidence": [ { "id": "A0A3Q1NLJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLJ8" } ] }, { "ec_number": "7.6.2.2", "activity": "", "evidence": [ { "id": "A0A3Q1NLJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLJ8" } ] } ] }, { "uniprot_ac": "E1BNL1", "gene_name": "ABCC10", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNL1", "database": "UniProtKB", "url": 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"Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 598, "end_pos": 824, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "7.6.2.2", "ec_name": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "7.6.2.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2" }, { "id": "7.6.2.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=7.6.2.2" } ] }, { "ec_number": "7.6.2.3", "ec_name": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "7.6.2.3", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3" }, { "id": "7.6.2.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=7.6.2.3" } ] } ], 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{ "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "WDR3", "url": "https://www.uniprot.org/uniprotkb/E1BM03", "locus": { "chromosome": "3", "start_pos": 25250693, "end_pos": 25289418, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019937", "url": "https://www.ensembl.org/id/ENSBTAG00000019937" } ] } } ], "crossref": [ { "id": "E1BM03", "url": "https://alphafold.ebi.ac.uk/entry/E1BM03", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019937", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019937", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514870", "url": "https://www.ncbi.nlm.nih.gov/gene/514870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": 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Classification" ] }, { "id": "IPR051570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514870", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514870", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNIPLTC", "url": "https://omabrowser.org/oma/group/MNIPLTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM03", "url": "https://www.orthodb.org/?gene=E1BM03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19853", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19853", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19853:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19853:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25172", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25172", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25173", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25173", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179317", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179317", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T673", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T673", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T673-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T673-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM03", "url": "https://www.uniprot.org/uniprotkb/E1BM03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM03-1", "url": "https://www.uniprot.org/uniprotkb/E1BM03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLTKQYLRYVASAVFGLIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKHEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITSLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLVSEEKRLITGASDSELRAWDISYLQEIEDPEEPEPKKIKESSPGIQDSHEAEDGTLEMDETPEDRILTCRKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLEVFCILSKEEIQKKMDKKMKKAKKKAKLNSCNEEEEDLEVNVKMTLQDEIQRVANIKTSAKIKSFDLIHTPQGELKAVFLLQNNLVELYSLNASTPGPQPVRTNRITIGGHRSDVRTLSFSSDNIAILSAAADSIKIWNRSTLQCIRTMACEYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSLSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEEVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISYDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLRFVPKSHLFFTAGKDRKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEKEMQREAEYEESVAKEDQPAVPGETQGDNYFTGKKTIETVKAAERIMEAIELYREETAKLREHKAICKAAGKEVPLPINPILMAYGNISPSAYVLEIFKGIKSSELEESLLVLPFSYVPDILRLFNEFIQQGSDIELLCRCLFFLLRIHFGQITSNQMLVPVIEKLKETTISKVSQVRDVIGFNMAGLDYLKRECEAKSEVMFFADATSHLEEKKRKRKKREKLILTVT", "length": 943, "header": "tr|E1BM03-1|E1BM03_BOVIN Isoform 1 of WD repeat-containing protein 3 OS=Bos taurus OX=9913 GN=WDR3 PE=3 SV=2 CANONICAL=E1BM03-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T673-1", "url": "https://www.uniprot.org/uniprotkb/E1BM03/entry#A0AAA9T673-1", "sequence": { "sequence": "MGLTKQYLRYVASAVFGLIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKHEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITSLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEIEDPEEPEPKKIKESSPGIQDSHEAEDGTLEMDETPEDRILTCRKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLEVFCILSKEEIQKKMDKKMKKAKKKAKLNSCNEEEEDLEVNVKMTLQDEIQRVANIKTSAKIKSFDLIHTPQGELKAVFLLQNNLVELYSLNASTPGPQPVRTNRITIGGHRSDVRTLSFSSDNIAILSAAADSIKIWNRSTLQCIRTMACEYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSLSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEEVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISYDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLRFVPKSHLFFTAGKDRKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEKEMQREAEYEESVAKEDQPAVPGETQGDNYFTGKKTIETVKAAERIMEAIELYREETAKLREHKAICKAAGKEVPLPINPILMAYGNISPSAYVLEIFKGIKSSELEESLLVLPFSYVPDILRLFNEFIQQGSDIELLCRCLFFLLRIHFGQITSNQMLVPVIEKLKETTISKVSQVRDVIGFNMAGLDYLKRECEAKSEVMFFADATSHLEEKKRKRKKREKLILTVT", "length": 911, "header": "tr|A0AAA9T673-1|E1BM03_BOVIN Computationally mapped isoform of WD repeat-containing protein 3 OS=Bos taurus OX=9913 GN=WDR3 PE=3 SV=1 CANONICAL=E1BM03-1" }, "locus": { "chromosome": "3", "start_pos": 25285228, "end_pos": 25251274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103562.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103562.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092063.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092063.1" } ] } }, { "isoform_ac": "E1BM03-1", "url": "https://www.uniprot.org/uniprotkb/E1BM03/entry#E1BM03-1", "sequence": { "sequence": "MGLTKQYLRYVASAVFGLIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKHEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITSLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLVSEEKRLITGASDSELRAWDISYLQEIEDPEEPEPKKIKESSPGIQDSHEAEDGTLEMDETPEDRILTCRKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLEVFCILSKEEIQKKMDKKMKKAKKKAKLNSCNEEEEDLEVNVKMTLQDEIQRVANIKTSAKIKSFDLIHTPQGELKAVFLLQNNLVELYSLNASTPGPQPVRTNRITIGGHRSDVRTLSFSSDNIAILSAAADSIKIWNRSTLQCIRTMACEYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSLSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEEVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISYDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLRFVPKSHLFFTAGKDRKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEKEMQREAEYEESVAKEDQPAVPGETQGDNYFTGKKTIETVKAAERIMEAIELYREETAKLREHKAICKAAGKEVPLPINPILMAYGNISPSAYVLEIFKGIKSSELEESLLVLPFSYVPDILRLFNEFIQQGSDIELLCRCLFFLLRIHFGQITSNQMLVPVIEKLKETTISKVSQVRDVIGFNMAGLDYLKRECEAKSEVMFFADATSHLEEKKRKRKKREKLILTVT", "length": 943, "header": "tr|E1BM03-1|E1BM03_BOVIN Isoform 1 of WD repeat-containing protein 3 OS=Bos taurus OX=9913 GN=WDR3 PE=3 SV=2 CANONICAL=E1BM03-1" }, "locus": { "chromosome": "3", "start_pos": 25285228, "end_pos": 25251274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026561.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026561.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026561.5", "url": "https://www.ensembl.org/id/ENSBTAP00000026561.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514870", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514870", "resource": "KEGG Pathway" }, { "id": "R-BTA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A106-1", "protein_name": "WD repeat-containing protein 3", "gene_name": "Wdr3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLTKQYLRYVASAVFGLIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGAIRVFSLLSGEGNITFNGHRAAVTSLKYDQLGGRLASGSKDTDVIIWDVINESGLYRLKGHKDAVTQALFLRERNLLVTSGKDTMVKWWDLDNQHCFKTMVGHRTEVWGLVLVSEETRLITGAADSELRAWDIAYLQEIDDPEEPEPKKIKECPGIQDTPEAEDRTLEADDEKSEDRILSCRKAGSLMREGRDRVVNLAVDKTGRILACHGTDSVLEVFCILSKAEVQKKMDKKLKKARKKARLNSANEEEDPETSVSMTLQDEILRVTKIKTSAKIKSFDLIHSPQGELKAVFLLQNNLVELYSLSTSLPNPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAAESVKIWNRSTLQCIRTMPCEYALCSFFVPGDRQVVIGTKTGNMQLYDLASGNLLETIAAHDGALWSMSLSPDQRGFVTGGADKAVKFWDFELVTDKNSTQKRLSVKQTRILQLDEDVLYVCYSPDQRLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHRSLFAHDDSVMHLRFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSASHDKSLRLWERTREPLILEEERELQREAEYEESVAKEEQPAVPGETQGDNYFTGKKTIETVKAAERIMEAIELYREETAKMKEHRAICRAAGKEVPLPVNPILMAHGNISPSAYVLETFKGIRSSELEEALLVLPFSYVPDILTLFNGFIQTGSDVELLCRCLFFLLRIHFGQITSNQMLVPVIEKLKETTISKVRQVQDVIGFNMAGLNYLKRECEAKSEVMFFAEATSHLEEKKRKRKNRRKMILTLT", "length": 942 }, "evidence": [ { "id": "E1BM03", "url": "https://omabrowser.org/oma/group/E1BM03/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SAY9-1", "protein_name": "WD repeat-containing protein 3", "gene_name": "WDR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLTKQYLRYVASAVFGLIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKHEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAVTSLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVSSGKDTMVKWWDLDTQHCFKTVVGHRTEVWGLVLVSEEKRLITGASDSELRAWDIAYLEEIEDPEEPEPKKIKGSSPRMQDTDETEDGTLEMDEAPEDRILTCRKAGSIMREGRDRVVNLAVDRTGRILACHGTDSVLEVFRVLSIEEIQKKMDKKLKKARKKAKLNSGKEEEEDLEVSVEMTLQDEIQRVTNIKTSAKIKSFDLIHSPQGELKAVFLLQNNLVELYSLNPSVPASQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSGAAESIKIWNRSTLQCIRTMTCEYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETVDAHDGALWSLSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEEVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISYDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLKFVPKSHLFFTAGKDRKIKQWDADKFEHVQTLEGHHQEIWCLAISPSGDYVVSSSHDKSLRLWERTREPLILEEEREMQREAEYEESVAKEDQPAVPGETQGDNYFTGKKTIETIKAAERIMEAIELYREETAKMREHKAICKAAGKEVPLPINPILMAYGNISPSAYVLEIFKGIKSSELEESLLVLPFSYVPDILKLFNEFIQLGSDIELLCRCLFFLLRIHFGQITSNQMLVPVIEKLKETTISKVSQVRDVIGFNMAGLDFLKRECEARSEVMFFADATSHLEEKKRKRKKREKLILTFT", "length": 943 }, "evidence": [ { "id": "E1BM03", "url": "https://omabrowser.org/oma/group/E1BM03/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q12220-1", "protein_name": "U3 small nucleolar RNA-associated protein 12", "gene_name": "DIP2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVKSYQRFEQAAAFGVIASNANCVWIPASSGNSNGSGPGQLITSALEDVNIWDIKTGDLVSKLSDGLPPGASDARGAKPAECTYLEAHKDTDLLAVGYADGVIKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLRSHKDSITGFWCQGEDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVKDDLLITTGTDSQVKIWKLDIENDKMGGKLTEMGIFEKQSKQRGLKIEFITNSSDKTSFFYIQNADKTIETFRIRKEEEIARGLKKREKRLKEKGLTEEEIAKSIKESYSSFILHPFQTIRSLYKIKSASWTTVSSSKLELVLTTSSNTIEYYSIPYEKRDPTSPAPLKTHTIELQGQRTDVRSIDISDDNKLLATASNGSLKIWNIKTHKCIRTFECGYALTCKFLPGGLLVILGTRNGELQLFDLASSSLLDTIEDAHDAAIWSLDLTSDGKRLVTGSADKTVKFWDFKVENSLVPGTKNKFLPVLKLHHDTTLELTDDILCVRVSPDDRYLAISLLDNTVKVFFLDSMKFYLSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFGDCHKSLFAHQDSIMNVKFLPQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVATDGGFVVSSSHDHSIRIWEETEDQVFLEEEKEKELEEQYEDTLLTSLEEGNGDDAFKADASGEGVEDEASGVHKQTLESLKAGERLMEALDLGIAEIEGLEAYNRDMKLWQRKKLGEAPIKPQGNAVLIAVNKTPEQYIMDTLLRIRMSQLEDALMVMPFSYVLKFLKFIDTVMQNKTLLHSHLPLICKNLFFIIKFNHKELVSQKNEELKLQINRVKTELRSALKSTEDDLGFNVQGLKFVKQQWNLRHNYEFVDEYDQQEKESNSARKRVFGTVI", "length": 943 }, "evidence": [ { "id": "E1BM03", "url": "https://omabrowser.org/oma/group/E1BM03/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54S79-1", "protein_name": "WD repeat-containing protein 3 homolog", "gene_name": "wdr3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVKAYLKFVQDKVFGLISTSNSILDGSGKLAITGCGERISIWDLRKQVLNQSLYEEDIKAEVTNVCLSKDGALLASGYSDGSIRIWSMSDYQLQAVFNGHRGSVTTMTFNRLGNILVSGSKDTEVIVWDIITESGLFRLRGHRDQITSVKLLERSNHLITSSKDGFIKIWDTETQHCIQTIVGHRNPIWGIDVNPDETRLCSCTSDNQIRFWRIPSNERQREDGSGIEPKFIVNTPINSAVIIPDEINEDGSKKENSNNSNNNDIDDLEIISEEEFAKYYGSITVKAESVSGVRFDPTNKILAVQSTGKFVDLFKITHYDTMKLEEISIVEEMRHRQTIKTSSKVRFFSFGNDIKHWNKFVITLAGNSLEAYEIKEKEQGGGAFEVSSTLDQAGHRSDIRSLSLSSNDQMLVSTSSESVKVWNMKSLSCIRSIACDYGLCTVFAPGNLHVIVGTKTGTIEVFELASAARVASIKAHEGSVWSLVLTPDLRGVTSGGADKLVKFWDFELIASQENSKHKVLNLSLTKTLKVESDVLALKYSADNKFLAVSLLDNTVKIFYTDTVKFHLSLYGHKLPVMCLDISDDSTLIITGSADKNIKIWGLDYGDCHKSFFAHDDSIMQVSFIPSTHHFISASKDKRIKYWDADKFEHIQTIEAHHGEVWSLAMGSVGDFFISGSHDRSIRIFNQTETPIFVESDRQREMEQTWEATLEDDTRMRTKEMLEENAAAGKQTLETIMAGEDILDAIELCVQEKFKIDEYEKLLKTTKNQDEIPLYQPNIIMLGLSPSEYLWNRINRIRPSDLEEALRVLPFSVMRTLFEYFNLWVDQSGKSVEFIFKCSFFLIQTHQNQLSVSTEFIPILQHLNTSIKNRLQKERFTLGFNRSALSFVKREIEINQQYKFFDSDLYLNKNNKNNKDKDSNNNKKDNKKDNKKDNEKSLKRNRK", "length": 942 }, "evidence": [ { "id": "E1BM03", "url": "https://omabrowser.org/oma/group/E1BM03/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BHB4-1", "protein_name": "WD repeat-containing protein 3", "gene_name": "Wdr3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLTKQYLRYVASAVFGLIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGNKQEVTCLCPSPDGLHLAVGYEDGAIRIFSLLSGEGNITFNGHKAAVTSLKYDQLGGRLASGSKDTDVIIWDVINESGLYRLKGHKDAVTQALFLRERNLLVTSGKDTMVKWWDLDNQHCFKTMVGHRTEVWGLVLVSEEKRLITGAADSELRAWDIDYLQEIDDPEEPEPKKIKECPGIQDTPESEDSTLEADDEKSEDRILSCSKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLEVFCILSKAEVQKKMDKKLKKARKKARLNSANEEEDPETSVSMTLQDEILRVAKIKTSAKIKSFDLIHSPQGELKAVFLLQNNLVELYSLNASLPAPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMPCEYALCSFFVPGDRQVVIGTKTGNLQLYDLASGTLLETIAAHDGALWSMSLSPDQRGFVTGGADKAVKFWDFELVTDKNSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKVFYVDTLKFFLSLYGHKLPVLCMDISHDGALIATGSADRNVKIWGLDFGDCHRSLFAHDDSVMYLRFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSASHDKSLRLWERTREPLILEEEREMQREAEYEESVAKEDQPAVPGETQGDNYFTGKKTIETVKAAERIMEAIELHREETAKMKEHRAICKAAGKEVPLPVNPILMAHGNISPSAYVLETFKGIRSSELEEALLVLPFSYVPDVLTLFNEFIQTGLDVELLCRCLFFLLRIHFGQITSNQMLVPVIEKLKETTISKVRQVQDAIGFNMAGLDYLKRECEAKSEVMFFAEATSHLEEKKKKRKNRKRMILTLT", "length": 942 }, "evidence": [ { "id": "E1BM03", "url": "https://omabrowser.org/oma/group/E1BM03/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LVF2-1", "protein_name": "Transducin family protein / WD-40 repeat family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVKAYQRYDAATSFGVISSVDSNIAYDSTGKYVLAPALEKVGIWHVRQGVCSKTLTPSSSRGGPSLAVTSIASSASSLVAVGYADGSIRIWDTEKGTCEVNFNSHKGAVTALRYNKVGSMLASGSKDNDIILWDVVGESGLFRLRGHRDQVTDLVFLDGGKKLVSSSKDKFLRVWDLETQHCMQIVSGHHSEVWSVDTDPEERYVVTGSADQELRFYAVKEYSSNGSLVSDSNANEIKASEEHSTENKWEILKLFGEIQRQTKDRVARVRFNVSGKLLACQMAGKTIEIFRVLDEAEAKQKAKRRLRRKEKKSSKVGDENSTANGEASAKIELADAVSSPTVLDVFKLLQVIRAGRKISSFSFCPTAPKESLGTLALSLNNNSLEFYSLKSSENAKTVTIEHQGHRSDVRSVTLSEDNTLLMSTSHSEVKIWNPSTGSCLRTIDSGYGLCSLIVPQNKYGIVGTKSGVLEIIDIGSATKVEEVKAHGGTIWSITPIPNDSGFVTVSADHEVKFWEYQVKQKSGKATKKLTVSNVKSMKMNDDVLAVAISPDAKHIAVALLDSTVKVFYMDSLKFYLSLYGHKLPVMCIDISSDGELIVTGSQDKNLKIWGLDFGDCHKSIFAHGDSVMGVKFVRNTHYLFSIGKDRLVKYWDADKFEHLLTLEGHHAEIWCLAISNRGDFLVTGSHDRSMRRWDRSEEPFFLEEEKEKRLEELFESEIDNAADDRHGPMEEIPEEGVAALAGKKTIDVLSAADSIIDALEVAEDETKRHAAYEEEKTKGKVPEYLPNAVMFGLSPSEYVLRAISNVRTNDLEQTLLALPFSDSLKFLCYMKDWSLIPEKVELVSRIATIILQTHHNQLVTTPSARPILSVLRDILYSEIKACKDTIGFNLAAMDHVKQMMDARSDAPFKDAKAKLLEIRSQQAKRMASRGDTKMEKKRKKKQKKLEEGQHGHALF", "length": 955 }, "evidence": [ { "id": "E1BM03", "url": "https://omabrowser.org/oma/group/E1BM03/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UNX4-1", "protein_name": "WD repeat-containing protein 3", "gene_name": "WDR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLTKQYLRYVASAVFGVIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIEDPEEPDPKKIKGSSPGIQDTLEAEDGAFETDEAPEDRILSCRKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLELFCILSKKEIQKKMDKKMKKARKKAKLHSSKGEEEDPEVNVEMSLQDEIQRVTNIKTSAKIKSFDLIHSPHGELKAVFLLQNNLVELYSLNPSLPTPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMTCEYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEREMEREAEYEESVAKEDQPAVPGETQGDSYFTGKKTIETVKAAERIMEAIELYREETAKMKEHKAICKAAGKEVPLPSNPILMAYGSISPSAYVLEIFKGIKSSELEESLLVLPFSYVPDILKLFNEFIQLGSDVELICRCLFFLLRIHFGQITSNQMLVPVIEKLRETTISKVSQVRDVIGFNMAGLDYLKRECEAKSEVMFFADATSHLEEKKRKRKKREKLILTLT", "length": 943 }, "evidence": [ { "id": "E1BM03", "url": "https://omabrowser.org/oma/group/E1BM03/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VE98-1", "protein_name": "Small-subunit processome Utp12 domain-containing protein", "gene_name": "Dmel\\CG8064", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGLTKQYLAYRAIDSFNIITSGRANVNFAVVDKTEGRYVAAPAAENVIVWDLRMGDRKLTLRREKFEVTSLRVSPDHLHIAVGYADGMVQIFDLSSDRYYDPICTLALHKNAVSILRYDLQGMRLVSGGLDTELVVVDVVEQAGRARLSGHNAAITDAHFLQRLVDESIVVSCSKDTQIKFWNLETQFCFKTIVDNRTEVWALAFIGNLMVAGAGESGMNVYRLRKHDGAITETLESAVEGLSIDDEDTISPISVSNCGTIQRAGKGRTVNLVTDPSERVISCHGTNDLIENFYICTPDEVKKRLAKRLKKEKKVAEDEGSDEAKLSTEQSLSDEIKRLESIRAKQKIKSIDVVLGQNQELRVLVSLANNSLCLYSLEASIKTRKATDPSAKLLRSLTRLGHQSEVRSVCFSNDSLAIGSGAGESFKFWDRDAMQCLRTVPTDYILCSKFVPGDRYVLLGMKSGKLLIVDVAAADIVEEIPAHEGELWSIAILPDQKGCVTGSGDTTVKIWTFELIDAGEGAAQTKVLSLLHKNTLKLEETVLCLAVSPDMKYLAVGLLDATVKVFFLDTFKFYLSLYGHKLPVICLDISYDSNLIVTGSADRNVKVWGLNFGDCHRSIFAHDDSVMSVQFIPRTHMFFTCGKDGKVKQWDGDNFEKILTLPGHIGEAYCLSVSPNGRYLVTCGSDRTLRMFERTDETIVLKDVQEEEREQMENEQLATGEDNTVPLLPGLKMPSRKTVGSEQSAESILECLEISKQFELEAEEKPELHPLMQALQVKNPEDFLVSTLMRIRASDLEEALLLLPFSTVCEVLERLPTLLTQRPDQLELLCRVTIFLFKVHMKPISAAKNMKPLLVKLLSMLKRDVGQLRDVLGWNLHGLALLQTEVEQRDGVQLFREATQTRKKRDKKRREASKRRLQIQMV", "length": 922 }, "evidence": [ { "id": "E1BM03", "url": "https://omabrowser.org/oma/group/E1BM03/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1BM03", "url": "https://www.uniprot.org/uniprotkb/E1BM03" } ], "pmid": "" }, { "name": "Pwp2p-containing subcomplex of 90S preribosome", "id": "GO:0034388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034388", "evidence": [ { "database": "UniProtKB", "id": "E1BM03", "url": "https://www.uniprot.org/uniprotkb/E1BM03" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BM03", "url": "https://www.uniprot.org/uniprotkb/E1BM03" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "E1BM03", "url": "https://www.uniprot.org/uniprotkb/E1BM03" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "E1BM03", "url": "https://www.uniprot.org/uniprotkb/E1BM03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "E1BM03", "url": "https://www.uniprot.org/uniprotkb/E1BM03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM03-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 943, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM03-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM03" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM03" }, { "id": "PF04003", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small-subunit processome Utp12", "eco_id": "ECO_0000259", "start_pos": 805, "end_pos": 907, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 138, "end_pos": 140 }, { "start_pos": 395, "end_pos": 397 }, { "start_pos": 442, "end_pos": 444 }, { "start_pos": 532, "end_pos": 534 }, { "start_pos": 801, "end_pos": 803 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BN12-1", "uniprot_ac": "E1BN12", "uniprot_id": "E1BN12_BOVIN", "mass": { "chemical_mass": 49054.0, "monoisotopic_mass": 49054.0 }, "refseq": { "ac": "XP_024840881", "name": "kremen protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840881" }, "gene_names": [ { "name": "KREMEN2", "type": "recommended", "evidence": [ { "id": "E1BN12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN12" } ] }, { "name": "KREMEN2", "type": "synonym", "evidence": [ { "id": "XP_024840881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840881" } ] } ], "protein_names": [ { "name": "Kremen protein", "type": "recommended", "evidence": [ { "id": "E1BN12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN12/entry#names_and_taxonomy" } ] }, { "name": "Kringle-containing protein marking the eye and the nose", "type": "synonym", "evidence": [ { "id": "E1BN12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN12/entry#names_and_taxonomy" } ] }, { "name": "kremen protein 2", "type": "synonym", "evidence": [ { "id": "XP_024840881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840881" } ] } ], "function": [ { "annotation": "Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.", "evidence": [ { "database": "UniProtKB", "id": "E1BN12", "url": "https://www.uniprot.org/uniprotkb/E1BN12#function" }, { "database": "UniProtKB", "id": "PIRNR036961", "url": "https://www.uniprot.org/uniprotkb/PIRNR036961#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN12", "url": "https://www.uniprot.org/uniprotkb/E1BN12" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KREMEN2", "url": "https://www.uniprot.org/uniprotkb/E1BN12", "locus": { "chromosome": "25", "start_pos": 2375665, "end_pos": 2371153, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020190", "url": "https://www.ensembl.org/id/ENSBTAG00000020190" } ] } } ], "crossref": [ { "id": "E1BN12", "url": "https://alphafold.ebi.ac.uk/entry/E1BN12", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020190", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020190", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00108", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00108", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "618527", "url": "https://www.ncbi.nlm.nih.gov/gene/618527", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618527", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618527", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RNCSWVV", "url": "https://omabrowser.org/oma/group/RNCSWVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN12", "url": "https://www.orthodb.org/?gene=E1BN12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24269", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24269", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24269:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24269:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00051", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00051", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024840881", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840881", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T7A9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7A9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN12", "url": "https://www.uniprot.org/uniprotkb/E1BN12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN12-1", "url": "https://www.uniprot.org/uniprotkb/E1BN12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTRPPKALLLLLLLRLLPPRGASAGSLQSPGLSECFQVNGADYRGHQNRTGPRGAGRPCLYWDQTQQHSYSSASDPQGRWGLGAHNFCRNPDGDVQPWCYVAETEEGIYWRYCDIPTCHMPGYLGCFVDSGAPPALSGPSGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRPAPATDCDQICFGHPGQLCGGDGRLGIYEVSVGSCQGNWTAPQGVIYSPDFPDEYGPDRNCSWVLAPPGAALELAFRLFELADSHDRLELRDATSGSLLRAFDGARPPPPGPLRLRAAVLRLIFRSDARGHAQGFALTFQGLQDADADPAPLEGSTQTPAVPLDGANVSCSPGPGGPEASMGAQVFSTVTAVSVLLLLVLSLLRLLRGRGCLLAPGKGSPTLGPSRDPTRSWAVWYRRPRGVALPCPPGDPQVEGLTASYRPLSASSQSSLRSLISAL", "length": 462, "header": "tr|E1BN12-1|E1BN12_BOVIN Isoform 1 of Kremen protein OS=Bos taurus OX=9913 GN=KREMEN2 PE=4 SV=3 CANONICAL=E1BN12-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T7A9-1", "url": "https://www.uniprot.org/uniprotkb/E1BN12/entry#A0AAA9T7A9-1", "sequence": { "sequence": "MGTRPPKALLLLLLLRLLPPRGASAGSLQSPGLSECFQVNGADYRGHQNRTGPRGAGRPCLYWDQTQQHSYSSASDPQGRWGLGAHNFCRNPDGDVQPWCYVAETEEGIYWRYCDIPTCHMPGYLGCFVDSGAPPALSGPSGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRPAPATDCDQICFGHPGQLCGGDGRLGIYEVSVGSCQGNWTAPQGVIYSPDFPDEYGPDRNCSWVLAPPGAALELAFRLFELADSHDRLELRDATSGSLLRAFDGARPPPPGPLRLRAAVLRLIFRSDARGHAQGFALTFQGLQDADADPAPLEGSTQTPAVPLDGANVSCSPGPGGPEASMGGETGVGGGSEFGGGPSKPVLTGLVCPQPRSSRR", "length": 399, "header": "tr|A0AAA9T7A9-1|E1BN12_BOVIN Computationally mapped isoform of Kremen protein OS=Bos taurus OX=9913 GN=KREMEN2 PE=4 SV=1 CANONICAL=E1BN12-1" }, "locus": { "chromosome": "25", "start_pos": 2374776, "end_pos": 2371361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129156.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129156.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092630.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092630.1" } ] } }, { "isoform_ac": "E1BN12-1", "url": "https://www.uniprot.org/uniprotkb/E1BN12/entry#E1BN12-1", "sequence": { "sequence": "MGTRPPKALLLLLLLRLLPPRGASAGSLQSPGLSECFQVNGADYRGHQNRTGPRGAGRPCLYWDQTQQHSYSSASDPQGRWGLGAHNFCRNPDGDVQPWCYVAETEEGIYWRYCDIPTCHMPGYLGCFVDSGAPPALSGPSGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRPAPATDCDQICFGHPGQLCGGDGRLGIYEVSVGSCQGNWTAPQGVIYSPDFPDEYGPDRNCSWVLAPPGAALELAFRLFELADSHDRLELRDATSGSLLRAFDGARPPPPGPLRLRAAVLRLIFRSDARGHAQGFALTFQGLQDADADPAPLEGSTQTPAVPLDGANVSCSPGPGGPEASMGAQVFSTVTAVSVLLLLVLSLLRLLRGRGCLLAPGKGSPTLGPSRDPTRSWAVWYRRPRGVALPCPPGDPQVEGLTASYRPLSASSQSSLRSLISAL", "length": 462, "header": "tr|E1BN12-1|E1BN12_BOVIN Isoform 1 of Kremen protein OS=Bos taurus OX=9913 GN=KREMEN2 PE=4 SV=3 CANONICAL=E1BN12-1" }, "locus": { "chromosome": "25", "start_pos": 2375299, "end_pos": 2371361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026893.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026893.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026893.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026893.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:618527", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618527", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287APD0-1", "protein_name": "Kremen protein", "gene_name": "KREMEN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGTQAPQGLLLLFLFPLLPPGGASAGSLHSPGLSECFQVNGADYRGHQNRTGPRGAGRPCLYWDQTQQHSYSSASDPQGRWGLGAHNFCRNPDGDVQPWCYVAETEEGIYWRYCDIPTCHMPGYLGCFMDSGAPPALSGPSGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRPAPATDCDQICFGHPGQLCGGDGRLGIYEVSVGSCQGNWTAPQGVVYSPDFPDEYGPDRNCSWALGPPGAALELTFRLFELADPRDRLELRDAASGNLLRAFDGARPPPPGPLRLRAAALLLTFHSDARGHAQGFALTYRGLQDAADDPEPPKGSAQTPAVPLEANVSCSPRPRAPEAAMGARVFSSVTAVSVLLLLLLWLLRLLRGRTCLLAPGKEPPALGPSGGPARSWAVWYRRPQGVALPSPPGDPQVESLTASYRPLSASSQSSLRSLISAL", "length": 461 }, "evidence": [ { "id": "E1BN12", "url": "https://omabrowser.org/oma/group/E1BN12/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4ADS5-1", "protein_name": "Kremen protein", "gene_name": "Kremen2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTPDLQGLLLLFPLLLPPHGASAGSLHSPGLSECFQVNGADYRGHQNYTGPRGAGRPCLFWDQTQQHSYSSASDPQGRWGLGAHNFCRNPDGDVQPWCYVAETEEGIYWRYCDIPTCHMPGYLGCFVDSGAPPALSGPSGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRPAPATDCDQICFGHPGQLCGGDGRLGIYEVSVGSCQGNWTAPQGVIYSPDFPDEYGPDRNCSWVLGQLGAVLELTFRLFELADSRDRLELRDASSGNLLRAFDGAHPPPPGPLHLRTAALLLTFRSDARGHAQGFALTYRGLQDTVEDRASPEDSAETLAGNPDGANVSCSPKPGAAQASIGARVFSTVMAISVLLLLLLLSLLRLLRRRSCLLAPGKGSLAMGPSRGPGRSWAVWYRRPRGVALPCPPGDSQAEGPAAGYRPLSASSQSSLRSLVSAL", "length": 462 }, "evidence": [ { "id": "E1BN12", "url": "https://omabrowser.org/oma/group/E1BN12/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K1S7-1", "protein_name": "Kremen protein 2", "gene_name": "Kremen2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTPHLQGFLLLFPLLLRLHGASAGSLHSPGLSECFQVNGADYRGHQNYTGPRGAGRPCLFWDQTQQHSYSSASDPQGRWGLGAHNFCRNPDGDVQPWCYVAETEEGIYWRYCDIPTCHMPGYLGCFVDSGAPPALSGPSGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRPAPATDCDQICFGHPGQLCGGDGRLGIYEVSVGSCQGNWSAPQGVIYSPDFPDEYGPDRNCSWVLGQLGAVLELTFRLFELADSRDRLELRDVSSGNLLRAFDGAHPPPPGPLRLRTAALLLTFRSDARGHAQGFALTYRGLQDTVEGRASPEDSTESLAGDPDGANASCSPKPGAAQASIGARVFSTVTAFSVLLLLLLSLLRLLRRRSCLLAPGKGSLAMGPSRGPGRSWAVWYRRPRGVALPCPPGDSQAEGPAAGYRPLSASSQSSLRSLVSAL", "length": 461 }, "evidence": [ { "id": "E1BN12", "url": "https://omabrowser.org/oma/group/E1BN12/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NCW0-1", "protein_name": "Kremen protein 2", "gene_name": "KREMEN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTQALQGFLFLLFLPLLQPRGASAGSLHSPGLSECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNPDGDVQPWCYVAETEEGIYWRYCDIPSCHMPGYLGCFVDSGAPPALSGPSGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRLAPATDCDQICFGHPGQLCGGDGRLGVYEVSVGSCQGNWTAPQGVIYSPDFPDEYGPDRNCSWALGPPGAALELTFRLFELADPRDRLELRDAASGSLLRAFDGARPPPSGPLRLGTAALLLTFRSDARGHAQGFALTYRGLQDAAEDPEAPEGSAQTPAAPLDGANVSCSPRPGAPPAAIGARVFSTVTAVSVLLLLLLGLLRPLRRRSCLLAPGKGPPALGASRGPRRSWAVWYQQPRGVALPCSPGDPQAEGSAAGYRPLSASSQSSLRSLISAL", "length": 462 }, "evidence": [ { "id": "E1BN12", "url": "https://omabrowser.org/oma/group/E1BN12/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BN12", "url": "https://www.uniprot.org/uniprotkb/E1BN12" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BN12", "url": "https://www.uniprot.org/uniprotkb/E1BN12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "E1BN12", "url": "https://www.uniprot.org/uniprotkb/E1BN12" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BN12", "url": "https://www.uniprot.org/uniprotkb/E1BN12" } ], "pmid": "" }, { "name": "limb development", "id": "GO:0060173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060173", "evidence": [ { "database": "UniProtKB", "id": "E1BN12", "url": "https://www.uniprot.org/uniprotkb/E1BN12" } ], "pmid": "" }, { "name": "negative regulation of ossification", "id": "GO:0030279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030279", "evidence": [ { "database": "UniProtKB", "id": "E1BN12", "url": "https://www.uniprot.org/uniprotkb/E1BN12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "E1BN12", "url": "https://www.uniprot.org/uniprotkb/E1BN12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN12-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 462, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN12-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN12" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN12" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 219, "end_pos": 326, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BN12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN12" }, { "id": "PS50070", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50070" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kringle", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 119, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BN12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN12" }, { "id": "PS51212", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51212" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WSC", "eco_id": "ECO_0000259", "start_pos": 121, "end_pos": 215, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 351, "end_pos": 353 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNH4-1", "uniprot_ac": "E1BNH4", "uniprot_id": "E1BNH4_BOVIN", "mass": { "chemical_mass": 57285.0, "monoisotopic_mass": 57285.0 }, "refseq": { "ac": "NP_001192697", "name": "zinc finger and BTB domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192697" }, "gene_names": [ { "name": "ZBTB2", "type": "recommended", "evidence": [ { "id": "E1BNH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" } ] }, { "name": "ZBTB2", "type": "synonym", "evidence": [ { "id": "NP_001192697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192697" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain containing 2", "type": "synonym", "evidence": [ { "id": "E1BNH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001192697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192697" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNH4", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZBTB2", "url": "https://www.uniprot.org/uniprotkb/E1BNH4", "locus": { "chromosome": "9", "start_pos": 88411605, "end_pos": 88440242, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014790", "url": "https://www.ensembl.org/id/ENSBTAG00000014790" } ] } } ], "crossref": [ { "id": "E1BNH4", "url": "https://alphafold.ebi.ac.uk/entry/E1BNH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014790", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014790", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18193", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18193", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513775", "url": "https://www.ncbi.nlm.nih.gov/gene/513775", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513775", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513775", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSCHLCR", "url": "https://omabrowser.org/oma/group/YSCHLCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNH4", "url": "https://www.orthodb.org/?gene=E1BNH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192697", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192697", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TH18", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TH18-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH4", "url": "https://www.uniprot.org/uniprotkb/E1BNH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNH4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLANHGLILLQQLNAQREFGFLCDCTVAIGDVYFKAHKSVLASFSNYFKMLFVHQTSECVRLKPTDIQPDIFSYLLHLMYTGKMAPQLIDPVRLEQGIKFLHAYPLIQEASLASQGAFSHPDQVFPLASSLYGIQIADHQLRQATKITSAPEKLGREPRPQATRMSQEQGPEASQLSQLPSNLSQVNRTHMTPSDPLQTSLSPDLVSTPVPPPPPGEETNLEASSSDEQPAPLTIAHVKPSIMKRNGSFPKYYACHLCGRRFTLRSSLREHLQIHTGVPFTASQPGESRVPLSLCSNAADLGKDAMEVPEAGIISDSELQHISDSPIIDGQPHSETPPPSDIADIDNLEQADQEREVKRRKYECTICGRKFIQKSHWREHMYIHTGKPFKCSTCDKSFCRANQAARHVCLNQSIDTYTMVDKQTLELCTFEEGSQMDNMLVQTNKPYKCNLCDKTFSTPNEVVKHSCQNQNSDVFALEEGRSILLGSGDSEVTEPDHPVLASIKKEQETVLLD", "length": 514, "header": "tr|E1BNH4-1|E1BNH4_BOVIN Isoform 1 of Zinc finger and BTB domain containing 2 OS=Bos taurus OX=9913 GN=ZBTB2 PE=4 SV=1 CANONICAL=E1BNH4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TH18-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH4/entry#A0AAA9TH18-1", "sequence": { "sequence": "MCTSRHTNQFLLHSPITLRCCLSIRPEKSPWFLRKMILLLPSCSQGCRLHFDDSESPLFFCLLHRRLLQFCECVRLKPTDIQPDIFSYLLHLMYTGKMAPQLIDPVRLEQGIKFLHAYPLIQEASLASQGAFSHPDQVFPLASSLYGIQIADHQLRQATKITSAPEKLGREPRPQATRMSQEQGPEASQLSQLPSNLSQVNRTHMTPSDPLQTSLSPDLVSTPVPPPPPGEETNLEASSSDEQPAPLTIAHVKPSIMKRNGSFPKYYACHLCGRRFTLRSSLREHLQIHTGVPFTASQPGESRVPLSLCSNAADLGKDAMEVPEAGIISDSELQHISDSPIIDGQPHSETPPPSDIADIDNLEQADQEREVKRRKYECTICGRKFIQKSHWREHMYIHTGKPFKCSTCDKSFCRANQAARHVCLNQSIDTYTMVDKQTLELCTFEEGSQMDNMLVQTNKPYKCNLCDKTFSTPNEVVKHSCQNQNSDVFALEEGRSILLGSGDSEVTEPDHPVLASIKKEQETVLLD", "length": 527, "header": "tr|A0AAA9TH18-1|E1BNH4_BOVIN Computationally mapped isoform of Zinc finger and BTB domain containing 2 OS=Bos taurus OX=9913 GN=ZBTB2 PE=4 SV=1 CANONICAL=E1BNH4-1" }, "locus": { "chromosome": "9", "start_pos": 88420499, "end_pos": 88413007, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104332.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104332.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097829.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097829.1" } ] } }, { "isoform_ac": "E1BNH4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNH4/entry#E1BNH4-1", "sequence": { "sequence": "MDLANHGLILLQQLNAQREFGFLCDCTVAIGDVYFKAHKSVLASFSNYFKMLFVHQTSECVRLKPTDIQPDIFSYLLHLMYTGKMAPQLIDPVRLEQGIKFLHAYPLIQEASLASQGAFSHPDQVFPLASSLYGIQIADHQLRQATKITSAPEKLGREPRPQATRMSQEQGPEASQLSQLPSNLSQVNRTHMTPSDPLQTSLSPDLVSTPVPPPPPGEETNLEASSSDEQPAPLTIAHVKPSIMKRNGSFPKYYACHLCGRRFTLRSSLREHLQIHTGVPFTASQPGESRVPLSLCSNAADLGKDAMEVPEAGIISDSELQHISDSPIIDGQPHSETPPPSDIADIDNLEQADQEREVKRRKYECTICGRKFIQKSHWREHMYIHTGKPFKCSTCDKSFCRANQAARHVCLNQSIDTYTMVDKQTLELCTFEEGSQMDNMLVQTNKPYKCNLCDKTFSTPNEVVKHSCQNQNSDVFALEEGRSILLGSGDSEVTEPDHPVLASIKKEQETVLLD", "length": 514, "header": "tr|E1BNH4-1|E1BNH4_BOVIN Isoform 1 of Zinc finger and BTB domain containing 2 OS=Bos taurus OX=9913 GN=ZBTB2 PE=4 SV=1 CANONICAL=E1BNH4-1" }, "locus": { "chromosome": "9", "start_pos": 88420593, "end_pos": 88413007, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019675.5", "url": "https://www.ensembl.org/id/ENSBTAT00000019675.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019675.3", "url": "https://www.ensembl.org/id/ENSBTAP00000019675.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:513775", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513775", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FGG7-1", "protein_name": "Zinc finger and BTB domain-containing protein 2 isoform X1", "gene_name": "Zbtb2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCTSRHTNQFLLHSPITLRCCLSIRPEIRISFCSGYCRTSFSEDGLRRAPYFFTIAVWSGSDTSLKGRQPAGSLCSECVRLKPTDIQPDIFSYLLHLMYTGKMAPQLIDPVRLEQGIKFLHAYPLIQEASLASQGTFSHPEQVFPLASSLYGIQIADHQLRQATKMNLGPEKLGREPRPQASRMNQEPVPETSQLSQLTTNLAQVNRTNMTPADPLQTSLSPELVSTPVPPPPPGEETNLEASSSDEQPSSLTIAHVKPSIMKRNGSFPKYYACHLCGRRFTLRSSLREHLQIHTGVPFTAGPPGEGRGPLSLCNNAADLGKDALEVPEGGMISDSELQHISDSPIIDGQQQSETPPPSDIADIDNLEQADQEREVKRRKYECTICGRKFIQKSHWREHMYIHTGKPFKCSTCDKSFCRANQAARHVCLNQSIDTYTMVDKQTLELCTFEEGSQMDNMLVQANKPYKCNLCDKTFSTPNEVVKHSCQNQNSDVFALDEGRSVLLGSGDSEVTESDRPVLASIKKEQETVLLD", "length": 532 }, "evidence": [ { "id": "E1BNH4", "url": "https://omabrowser.org/oma/group/E1BNH4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4ABS0-1", "protein_name": "Zinc finger and BTB domain containing 2", "gene_name": "Zbtb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTPVPGLRAKQLNAQREFGFLCDCTVAIGDVYFKAHKSVLASFSNYFKMLFVHQTSECVRLKPTDIQPDIFSYLLHLMYTGKMAPQLIDPVRLEQGIKFLHAYPLIQEASLASQGTFSHPEQVFPLASSLYGIQIADHQLRQATKMNLGPEKLGREPRPQASRMNQEPVPETSQLSQLTSNLAQVNRTNMTPADPLQTSLSPELVSTPVPPPPPGEETNLEASSSDEQPSSLTIAHVKPSIMKRNGSFPKYYACHLCGRRFTLRSSLREHLQIHTGVPFTAGPPGEGRGPLSLCSNAADLGKDALEVPEAGMISDSELQHISDSPIIDGQQQSETPPPSDIADIDNLEQADQEREVKRRKYECTICGRKFIQKSHWREHMYIHTGKPFKCSTCDKSFCRANQAARHVCLNQSIDTYTMVDKQTLELCTFEEGSQMDNMLVQANKPYKCNLCDKTFSTPNEVVKHSCQNQNSDVFALDEGRSVLLGSGDSEVTDPDHPVLAAIKKEQETVLLD", "length": 512 }, "evidence": [ { "id": "E1BNH4", "url": "https://omabrowser.org/oma/group/E1BNH4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S7W1-1", "protein_name": "Zinc finger and BTB domain containing 2", "gene_name": "ZBTB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLANHGLILLQQLNAQREFGFLCDCTVAIGDVYFKAHKSVLASFSNYFKMLFVHQTSECVRLKPTDIQPDIFSYLLHLMYTGKMAPQLIDPVRLEQGIKFLHAYPLIQEASLASQGAFSHPDQVFPLASSLYGIQIADHQLRQATKIASAPDKLGREARPQPPRMSQEQVPEASQLSQLPANLTQVNRTHMTPSDPLQTSLSPDLVSTPVPPPPPGEETNLEASSSDEQPASLTIAHVKPSIMKRNGSFPKYYACHLCGRRFTLRSSLREHLQIHTGVPFPASQPGESRVPLSLCSTTADLGKDAMEVPEAGMISDSELQHISDSPIIDGQPHSETPPPSDIADIDNLEQADQEREVKRRKYECTICGRKFIQKSHWREHMYIHTGKPFKCSTCDKSFCRANQAARHVCLNQSIDTYTMVDKQTLELCTFEEGSQMDNLLVQTNKPYKCNLCDKTFSTPNEVVKHSCQNQNSDVFALDEGRSILLGSGDSEVTEPDHPVLASIKKEQETVLLD", "length": 514 }, "evidence": [ { "id": "E1BNH4", "url": "https://omabrowser.org/oma/group/E1BNH4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z4W3-1", "protein_name": "Zinc finger and BTB domain-containing protein 2b", "gene_name": "zbtb2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MELANHGLILLQQLNAQREFGFLCDCTVAIGDVFFKAHKAVLAAFSNYFRMLFIHQDSDCVRLKPADIQPDIFSYLLNLMYTGKLATQLIDPARLEQGVKFLHAYPLIQEATLASHAPQAHPEVNLPLSSSLYGIQISDQQATLTNRLSARTPLSSPFDLEGTGLLDGKSSAASKATSLTRSGTKHRHAPSEPEVEASASISQFLRESAEPETSATEAPSCSLSANTILHVKPSIMRRTSSLRKHYTCHVCGGRFTQRGALREHLLLHTQAMLPLVLESVGATSPMLSGGAATPEVEEVLRGSEAAAATPIIVDVPSDSEQHSYSKDSPHPETAIPVPTTTAVSLCTAQPQADTPPPSDIADIDNLEGAADMEREVKRRKYECSTCGRKFIQKSHWREHMYIHTGKPYRCSACGKSFCRANQAARHVCMNLGSEPAYTMVDRQSMELCAADDSSQMEAMFLGSSGRPYKCNVCEMTFSSPNEVIKHLCFNQGALSGGAAGEMGVSGMNSDSLAKDEGSDSSNGGPLMTPIKTEEVFVE", "length": 538 }, "evidence": [ { "id": "E1BNH4", "url": "https://omabrowser.org/oma/group/E1BNH4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N680-1", "protein_name": "Zinc finger and BTB domain-containing protein 2", "gene_name": "ZBTB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLANHGLILLQQLNAQREFGFLCDCTVAIGDVYFKAHKSVLASFSNYFKMLFVHQTSECVRLKPTDIQPDIFSYLLHLMYTGKMAPQLIDPVRLEQGIKFLHAYPLIQEASLASQGAFSHPDQVFPLASSLYGIQIADHQLRQATKIASAPEKLGRDPRPQTSRISQEQVPEASQLSQLTSNLAQVNRTNMTPSDPLQTSLSPELVSTPVPPPPPGEETNLEASSSDEQPASLTIAHVKPSIMKRNGSFPKYYACHLCGRRFTLRSSLREHLQIHTGVPFTSSQQGESRVPLTLCSNAADLGKDAMEVPEAGMISDSELQHISDSPIIDGQQQSETPPPSDIADIDNLEQADQEREVKRRKYECTICGRKFIQKSHWREHMYIHTGKPFKCSTCDKSFCRANQAARHVCLNQSIDTYTMVDKQTLELCTFEEGSQMDNMLVQTNKPYKCNLCDKTFSTPNEVVKHSCQNQNSDVFALDEGRSILLGSGDSEVTEPDHPVLASIKKEQETVLLD", "length": 514 }, "evidence": [ { "id": "E1BNH4", "url": "https://omabrowser.org/oma/group/E1BNH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BNH4", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BNH4", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BNH4", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BNH4", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BNH4", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BNH4", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BNH4", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "E1BNH4", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "E1BNH4", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNH4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 514, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNH4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNH4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 89, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 254, "end_pos": 278, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 412, "end_pos": 414 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNQ5-1", "uniprot_ac": "E1BNQ5", "uniprot_id": "E1BNQ5_BOVIN", "mass": { "chemical_mass": 28951.0, "monoisotopic_mass": 28951.0 }, "refseq": { "ac": "XP_005227162", "name": "basic leucine zipper transcriptional factor ATF-like 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227162" }, "gene_names": [ { "name": "BATF2", "type": "recommended", "evidence": [ { "id": "E1BNQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" } ] }, { "name": "BATF2", "type": "synonym", "evidence": [ { "id": "XP_005227162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227162" } ] } ], "protein_names": [ { "name": "Basic leucine zipper transcriptional factor ATF-like 2", "type": "recommended", "evidence": [ { "id": "E1BNQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5/entry#names_and_taxonomy" } ] }, { "name": "basic leucine zipper transcriptional factor ATF-like 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005227162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227162" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNQ5", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BATF2", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5", "locus": { "chromosome": "29", "start_pos": 43205957, "end_pos": 43212743, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011467", "url": "https://www.ensembl.org/id/ENSBTAG00000011467" } ] } } ], "crossref": [ { "id": "E1BNQ5", "url": "https://alphafold.ebi.ac.uk/entry/E1BNQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011467", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011467", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14701", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14701", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "522469", "url": "https://www.ncbi.nlm.nih.gov/gene/522469", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BNQ5", "url": "https://www.orthodb.org/?gene=E1BNQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23351:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23351:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005227162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227162", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TI43", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TI43-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNQ5", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNQ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLCGGDGPLTRTDAEEHQRQLRKKQKNRAAAQRSRQKHTNKADALHQHESLEKQNHALRKEIQALQAELAWWTQALHVHERLCLLDCASCLAPGAAGCWGQAERPPGSVPHGQHGCQEQLGLFRTPVSSPSAPQPSPDPQPHGSLSLLLSPLPSLSLGPTAVTASPAQLSPSPAQSTSPAGSGLLKPSSKLNIVLPSPTAQPAPLEFLRLEHPNGGKPGSTPHSPSAATGLGSLQGREHKPASSAADWQGLGVDPSPHPLLDFPLLSSAQVHF", "length": 274, "header": "tr|E1BNQ5-1|E1BNQ5_BOVIN Isoform 1 of Basic leucine zipper transcriptional factor ATF-like 2 OS=Bos taurus OX=9913 GN=BATF2 PE=3 SV=2 CANONICAL=E1BNQ5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TI43-1", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5/entry#A0AAA9TI43-1", "sequence": { "sequence": "MPCTRWQPTRLPRPWDSPGKNTGQHESLEKQNHALRKEIQALQAELAWWTQALHVHERLCLLDCASCLAPGAAGCWGQAERPPGSVPHGQHGCQEQLGLFRTPVSSPSAPQPSPDPQPHGSLSLLLSPLPSLSLGPTAVTASPAQLSPSPAQSTSPAGSGLLKPSSKLNIVLPSPTAQPAPLEFLRLEHPNGGKPGSTPHSPSAATGLGSLQGREHKPASSAADWQGLGVDPSPHPLLDFPLLSSAQVHF", "length": 250, "header": "tr|A0AAA9TI43-1|E1BNQ5_BOVIN Computationally mapped isoform of Basic leucine zipper transcriptional factor ATF-like 2 OS=Bos taurus OX=9913 GN=BATF2 PE=3 SV=1 CANONICAL=E1BNQ5-1" }, "locus": { "chromosome": "29", "start_pos": 43210857, "end_pos": 43206961, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113093.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113093.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097950.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097950.1" } ] } }, { "isoform_ac": "E1BNQ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5/entry#E1BNQ5-1", "sequence": { "sequence": "MHLCGGDGPLTRTDAEEHQRQLRKKQKNRAAAQRSRQKHTNKADALHQHESLEKQNHALRKEIQALQAELAWWTQALHVHERLCLLDCASCLAPGAAGCWGQAERPPGSVPHGQHGCQEQLGLFRTPVSSPSAPQPSPDPQPHGSLSLLLSPLPSLSLGPTAVTASPAQLSPSPAQSTSPAGSGLLKPSSKLNIVLPSPTAQPAPLEFLRLEHPNGGKPGSTPHSPSAATGLGSLQGREHKPASSAADWQGLGVDPSPHPLLDFPLLSSAQVHF", "length": 274, "header": "tr|E1BNQ5-1|E1BNQ5_BOVIN Isoform 1 of Basic leucine zipper transcriptional factor ATF-like 2 OS=Bos taurus OX=9913 GN=BATF2 PE=3 SV=2 CANONICAL=E1BNQ5-1" }, "locus": { "chromosome": "29", "start_pos": 43212544, "end_pos": 43206961, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015237.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015237.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015237.4", "url": "https://www.ensembl.org/id/ENSBTAP00000015237.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ5", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ5", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ5", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ5", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ5", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ5", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" } ], "pmid": "" }, { "name": "defense response to protozoan", "id": "GO:0042832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042832", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ5", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" } ], "pmid": "" }, { "name": "myeloid dendritic cell differentiation", "id": "GO:0043011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043011", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ5", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BNQ5", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNQ5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 274, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNQ5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNQ5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ5" }, { "id": "PS00036", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00036" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 38, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMR3-1", "uniprot_ac": "E1BMR3", "uniprot_id": "E1BMR3_BOVIN", "mass": { "chemical_mass": 120593.0, "monoisotopic_mass": 120593.0 }, "refseq": { "ac": "NP_001179531", "name": "retinoblastoma-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179531" }, "gene_names": [ { "name": "RBL1", "type": "recommended", "evidence": [ { "id": "E1BMR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ] }, { "name": "RBL1", "type": "synonym", "evidence": [ { "id": "NP_001179531", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179531" } ] } ], "protein_names": [ { "name": "Retinoblastoma-like protein 1", "type": "recommended", "evidence": [ { "id": "E1BMR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR3/entry#names_and_taxonomy" } ] }, { "name": "107 kDa retinoblastoma-associated protein", "type": "synonym", "evidence": [ { "id": "E1BMR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR3/entry#names_and_taxonomy" } ] }, { "name": "pRb1", "type": "synonym", "evidence": [ { "id": "E1BMR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR3/entry#names_and_taxonomy" } ] }, { "name": "retinoblastoma-like 1 (p107)", "type": "synonym", "evidence": [ { "id": "NP_001179531", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179531" } ] }, { "name": "retinoblastoma-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_001179531", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179531" } ] } ], "function": [ { "annotation": "Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. May act as a tumor suppressor.", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3#function" }, { "database": "UniProtKB", "id": "ARBA00056699", "url": "https://www.uniprot.org/uniprotkb/ARBA00056699#function" }, { "database": "UniProtKB", "id": "A0AAA9TIM8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIM8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RBL1", "url": "https://www.uniprot.org/uniprotkb/E1BMR3", "locus": { "chromosome": "13", "start_pos": 66015119, "end_pos": 66074734, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011541", "url": "https://www.ensembl.org/id/ENSBTAG00000011541" } ] } } ], "crossref": [ { "id": "E1BMR3", "url": "https://alphafold.ebi.ac.uk/entry/E1BMR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011541", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011541", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20605", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20605", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "524870", "url": "https://www.ncbi.nlm.nih.gov/gene/524870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524870", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524870", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AILCELH", "url": "https://omabrowser.org/oma/group/AILCELH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMR3", "url": "https://www.orthodb.org/?gene=E1BMR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13742:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13742:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08934", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08934", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11934", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11934", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1538133", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1538133", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2173796", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2173796", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-69231", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179531", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179531", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TIM8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIM8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMR3-1", "url": "https://www.uniprot.org/uniprotkb/E1BMR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEDDPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVIHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKFEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKELFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQELLNPSFKGLPSNFQTADFRASEEPPCIIPVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLCSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTGDGPLGKLTAQANVECNLQHHFEKKTSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSEQLINIFESCMRNPMENIMKIVKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHHSLMACCLEIVLFAYSSPRTFPWIIEVLNLRPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQASENRVPTCEEVIFPNNFETGSGGNVQGHLPMMPMSPLMHPRVKEVRTDSGSLRKDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEILMDRIITEGTKLKIAPSSSITAENISISPGHSLLTMATAIVAGTTGHKVTIPLHGIANDAGEITLIPISMNTTQESKVESPVSLTAQSLIGASPKQTHLTKAQEVHPIGISKPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYSKNLNGDFEMTDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLSNQDHVMEAPPLSPFPHIKQQPGSPRRISQQHSIYVSPHKNGSGLTPRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRAITIDGDAESPAKRLCQENDDVLLKRLQDVVSERANH", "length": 1068, "header": "tr|E1BMR3-1|E1BMR3_BOVIN Isoform 1 of Retinoblastoma-like protein 1 OS=Bos taurus OX=9913 GN=RBL1 PE=3 SV=1 CANONICAL=E1BMR3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TIM8-1", "url": "https://www.uniprot.org/uniprotkb/E1BMR3/entry#A0AAA9TIM8-1", "sequence": { "sequence": "MDEDDPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVIHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKFEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKELFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQELLNPSFKGLPSNFQTADFRASEEPPCIIPVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLCSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTGDGPLGKLTAQANVECNLQHHFEKKTSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSEQLINIFESCMRNPMENIMKIVKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHHSLMACCLEIVLFAYSSPRTFPWIIEVLNLRPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQASENRVPTCEEVIFPNNFETGSGGNVQGHLPMMPMSPLMHPRVKEVRTDSGSLRKDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEILMDRIITEGTKLKIAPSSSITAENISISPGHSLLTMATAIVAGTTGHKVTIPLHGIANDAGEITLIPISMNTTQESKVESPVSLTAQSLIGASPKQTHLTKAQEVHPIGISKPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYSKNLNGDFEMTDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLSNQDHVSLKDINNMIRQGEQRTKKRAITIDGDAESPAKRLCQENDDVLLKRLQDVVSERANH", "length": 1013, "header": "tr|A0AAA9TIM8-1|E1BMR3_BOVIN Computationally mapped isoform of Retinoblastoma-like protein 1 OS=Bos taurus OX=9913 GN=RBL1 PE=3 SV=1 CANONICAL=E1BMR3-1" }, "locus": { "chromosome": "13", "start_pos": 66074535, "end_pos": 66016123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124502.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124502.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098166.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098166.1" } ] } }, { "isoform_ac": "E1BMR3-1", "url": "https://www.uniprot.org/uniprotkb/E1BMR3/entry#E1BMR3-1", "sequence": { "sequence": "MDEDDPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVIHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKFEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKELFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQELLNPSFKGLPSNFQTADFRASEEPPCIIPVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLCSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTGDGPLGKLTAQANVECNLQHHFEKKTSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSEQLINIFESCMRNPMENIMKIVKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHHSLMACCLEIVLFAYSSPRTFPWIIEVLNLRPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQASENRVPTCEEVIFPNNFETGSGGNVQGHLPMMPMSPLMHPRVKEVRTDSGSLRKDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEILMDRIITEGTKLKIAPSSSITAENISISPGHSLLTMATAIVAGTTGHKVTIPLHGIANDAGEITLIPISMNTTQESKVESPVSLTAQSLIGASPKQTHLTKAQEVHPIGISKPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYSKNLNGDFEMTDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLSNQDHVMEAPPLSPFPHIKQQPGSPRRISQQHSIYVSPHKNGSGLTPRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRAITIDGDAESPAKRLCQENDDVLLKRLQDVVSERANH", "length": 1068, "header": "tr|E1BMR3-1|E1BMR3_BOVIN Isoform 1 of Retinoblastoma-like protein 1 OS=Bos taurus OX=9913 GN=RBL1 PE=3 SV=1 CANONICAL=E1BMR3-1" }, "locus": { "chromosome": "13", "start_pos": 66074535, "end_pos": 66016123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015333.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015333.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015333.5", "url": "https://www.ensembl.org/id/ENSBTAP00000015333.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:524870", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524870", "resource": "KEGG Pathway" }, { "id": "R-BTA-1538133", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1538133", "resource": "Reactome", "description": "G0 and Early G1" }, { "id": "R-BTA-2173796", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2173796", "resource": "Reactome", "description": "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" }, { "id": "R-BTA-69231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69231", "resource": "Reactome", "description": "Cyclin D associated events in G1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZZS3-1", "protein_name": "RB transcriptional corepressor like 1", "gene_name": "RBL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRAEPLPEPQPELELGAAIERLCRELNLDAGSAAEALRDFTALRGTYSLEGDAQHWLACALYAACRRSVLPTVGSGVMEGNCVSLTRILRSARLSLIQFFSKMKKWMDMSNVPQEFRERVERLERNFEVSTVIFRKFEPIFLDIFQNPNEETSKPQRSRKQRRVLCGVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLVFANAILCPNRRDLLNPSFKGTVGMGCSKRNTLCSFGYPFLSEAEGWSSFCFFSPTAFPGLPADFHAPEMKASEDPPCIIATLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLCNFTENNKALNKEYEEYVLTVGDFDERVFLGADAEEEIGTPRKFPADLQVGKTAARAHVECHLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQNIVAGLKNAPSELLMAIFESCARNPAESIVNRVREIGETFCRSYTQPTDELPGSHIDFAVNRLKLAEILYYKILETIMVQEMRRLHGKDMTALLEQDVFHRSLMACCLEIVLFAYSSPRTFPWIIEVLDLRPFYFYKVIEVLIRSEEGLSRDMVKHLNSIEEQILESLAWTRDSALWTALQASENRVPTCEEVIFPNNFEASNGGSGLGHLPMMPISPLVHPRVKEVRTDLGGSLRRDTQPLSPISVHERYSSPTAGSAKRRLFGDDGPKEMQMEKILTEGTKLTIAPASSIAAENVSISPGQTVLTVTTATVAGKPGQKVTIPLHGIAGDLGGITLIPIAMNLGQAPKIEAQDPCHPQVNQDQEVHLSSGNKPKKTGSLALFYRKVYHLASVRLRDLCLKLDVSNDLRRKIWTCFEFTLVHCADLMKDRHLDQLLLCAFYIMAKVTKEERTFQDIMKSYRNQPQANSHVYRSVLLRNTSANVLLDRNANQDVQMTEDSSVKTGNSLGRSAAENSTELGTEERGDLIKFYNAVYVGRVKSFALKYDITNQDHVMEAPPLSPFPSIKQQPVSPRRISQQHSVYVSPHKNGACLTPRTALLYKFNGSPSKSLKDINNMIKQGEHRSKKRAITIDSDTESPMKRLCQENDDVLLKRLQDVVSERANH", "length": 1100 }, "evidence": [ { "id": "E1BMR3", "url": "https://omabrowser.org/oma/group/E1BMR3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZS28-1", "protein_name": "Retinoblastoma-like protein 1", "gene_name": "Rbl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFEDEPHAEGAAAVAAAREALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVIHWLACSLYVACRKSIIPTVGKGVMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKFEPIFLDIFQNPYEELPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRRDLLNPSFKGLPSDFHAVNFKAAEEPPCIIAVLCDLHDGLLVEAKGIKEHYFKPYISKLFDKKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFAADTQFGKLTSQASVDCNLQQHFEKKRSFAPSTPLTGRRYLQEKEAVTTPVASATQSVSRLQSIVAGLKSAPSEQLLTIFESCMRNPMGNIVKIVKGIGETFCQHYTQSTDKQPGSHIDFAVNRLKLAEILYYKILETIMVQETRRLHGMDMSVLLEQDIFHRSLLACCLEIVLFAYSSPRTFPWIIDVLGLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWTNNSALWEALRASANKVPSCEEVIFPNNFEIGNGGSVQGHLPMMPMSPIIHPRVKEVRTDSGSLRKDMQPLSPISVHERYSSPAAGSAKRRLFGDDPPKETLMEKIMAEGTQLKIAPSSVTAESLSISPGQALLTMATTTVTGTTGRKVTVPLHGIANDAGEITLVPISMNTTQDSTAESLVSLTAQSLIGASPKQTHLTKTQDAPLTGISKPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPGEVVAYNGDYEMTDGDIEDATKTPNCSSEPVKEERGDLIKFYNAIYVGRVKSFALKYDLSNQDHIMDAPPLSPFPHIKQQPGSPRRISQQHSIYVSPHKNASGLTPRSALLYKFNGSPSKKAKKRVIAISGDAESPAKRLCQENDDVLLKRLQDVVSERANH", "length": 1049 }, "evidence": [ { "id": "E1BMR3", "url": "https://omabrowser.org/oma/group/E1BMR3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P28749-1", "protein_name": "Retinoblastoma-like protein 1", "gene_name": "RBL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNINDDFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKRLQDVVSERANH", "length": 1068 }, "evidence": [ { "id": "E1BMR3", "url": "https://omabrowser.org/oma/group/E1BMR3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q24472-1", "protein_name": "Retinoblastoma family protein", "gene_name": "Rbf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSEPDPQELGAEVVSGLVATSDDRLEMINAEYTNLCRDLNMDRQTELQGYETYLEVSQRCSMEGTASHWMCCAIYTACRRTSTPTVTGQNAVVKGNCVSLNNLLRCCKMSIYEFKTKIKQWCDMANLPQEFVNEIEDLDRKFSITFMLHKRFRIIMDMIFSCPPNEKKHSKYISLHGNHAHGKCSYIKLDDICWRLFLCAKNQKPSNTVDLVTSYNLMICCIDLIYNNVLAEKRTDLINPKFEGLPSNWTELDFRHNPHCILSNFCDMTEEAKAMKATTFRQIMSSFFQASTIYGNKDTMLGLLANENFERNLKSLNISYEQYVLSVGEFDERILSAYDAGEHTALNDQSLRPPVTPLTRKQDLPAQPAMAGDKFEPVRNATNNVKQLSAFGRITEPTDFVKQAGEEVIAKLLSIIEEIEQKFLAKYPSTEAKSRFQLAKSFFFYLLDQILQAEIRNKPDIDLKRLLVQKVSLVIFNITLMACCVELVLEAYKTELKFPWVLDCFSISAFEFQKIIEIVVRHGSHEGCLNRSLIKHLNSIEETCLERLAWARNSTVWEMIASAQLPLPTWLMVNLDRAAGPLQIFLRKVYLLGWLRIQKLCSELSLCEKTPESIWHIFEHSITHETELMKDRHLDQNIMCAIYIYIRVKRMEDPKFSDIMRAYRNQPQAVNSVYREVFIDINEDGEPKVKDIIHFYNHTYVPLMRQFVIDYLNVTPDVSGRASDLQLSPHPKERAAQPKKVTQSHSLFVSQMSKNEIQQSPNQMVYSFCRSPAKDLQAMNEKVRGGKRMLSFGDEPGLGTMAETKRSKISQVKAVMDDPELQSAEQQTAVTTEGCVGGEGGEHET", "length": 845 }, "evidence": [ { "id": "E1BMR3", "url": "https://omabrowser.org/oma/group/E1BMR3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q64701-1", "protein_name": "Retinoblastoma-like protein 1", "gene_name": "Rbl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFEDEPHAEGAAAVAAAREALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVIHWLACSLYVACRKSIIPTVGKGVMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKFEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRRDLLNPSFKGLPSDFHAPDFKAAEEPPCIIAVLCDLHDGLLVEAKGIKEHYFKPYISKLFDKKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTADTPFGKLTSQASVECNLQQHFEKKRSFAPSTPLTGRRYLQEKEAVTTPVASATQSVSRLQSIVAGLKSAPSEQLLNIFESCMRNPMGNIIKIVKGIGETFCQHYTQSTDKQPGSHIDFAVNRLKLAEILYYKILETIMVQETRRLHGMDMSVLLEQDIFHKSLMACCLEIVLFAYSSPRTFPWIIEVLDLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWTNNSALWEALHASANRVPSCEEVIFPNNFEIGNGGNVQGHLPMMPMSPIIHPRVKEVRTDSGSLRQDMQPLSPISVHERYSSPAAGSAKRRLFGDDPPKDTLMDKIMAEGTKLKIAPSSVTAESLSISPGQALLTMATTTVTGTTGRKVTVPLHGIANDAGEITLVPISMNPTQESTAESPVSLTAQSLIGTSPKQTHLTKAQDAHLTGVSKPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPGGVVVYNGDCEMTDGDIEDATKTPNCSSEPVKEERGDLIKFYNTVYVGRVKSFALKYDLSNQDHIMDAPPLSPFPHIKQQPGSPRRISQQHSLYVSPHKNGAGLTPRSALLYKFNGSPSKSLKDINNMIRQGEQKTKKRVIAISGDADSPAKRLCQENDDVLLKRLQDVVSERANH", "length": 1063 }, "evidence": [ { "id": "E1BMR3", "url": "https://omabrowser.org/oma/group/E1BMR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LKZ3-1", "protein_name": "Retinoblastoma-related protein 1", "gene_name": "RBR1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEVQPPVTPPIEPNGKRSEASLLDICEKVLSLDGSTCDEALKLFTETKRILSASMSNIGSGTREEVERFWFAFILYSVKRLSVRKEADGLSVSGDNEFNLCQILRALKLNIVDFFKELPQFVVKAGSVLGELYGADWENRLQAKEVQANFVHLSLLSKYYKRGFREFFLTYDANAEKNSANSSTYLLDSYRFGWLLFLALRNHAFSRFKDLVTCSNGVVSILAILIIHVPCRFRNFSIQDSSRFVKKGDKGVDLVASLCKIYDASEDELRIVIDKANNLVETILKKKPSPASECQTDKLDNIDPDGLTYFEDLLEETSISTSLITLEKDYYDGKGELDERVFINEEDSLLGSGSLSAGAVNITGVKRKIDALSSPARTFISPLSPHKSPAAKTNGISGATKLAATPVSTAMTTAKWLRTVISPLLPKPSPGLEHFLKSCDRDITNDVTRRAHIILEAIFPNSSLGAQCGGGSLQAVDLMDDIWAEQRRLEACKLYYRVLEAMCKAEAQILHANNLNSLLTNERFHRCMLACSAELVLATHKTITMLFPAVLERTGITAFDLSKVIESFIRHEDSLPRELRRHLNSLEERLLESMVWEKGSSMYNSLIVARPSLALEINQLGLLAEPMPSLDAIAALINFSDGANHASSVQKHETCPGQNGGIRSPKRLCTDYRSILVERNSFTSPVKDRLLALGNVKSKMLPPPLQSAFASPTRPNPGGGGETCAETGINIFFTKINKLAAVRINGMVERLQLSQQIRESVYCFFQHVLAQRTSLLFSRHIDQIILCCFYGVAKISQMSLTFREIIYNYRKQPQCKPLVFRSVYVDALQCRRQGRIGPDHVDIITFYNEIFIPAVKPLLVELGPVRNDRAVEANNKPEGQCPGSPKVSVFPSVPDMSPKKVSAVHNVYVSPLRGSKMDALISHSTKSYYACVGESTHAYQSPSKDLSAINNRLNNSSSNRKRTLNFDAEAGMVSDSMVANSLNLQNQNQNQNGSDASSSGGAAPLKTEPTDS", "length": 1013 }, "evidence": [ { "id": "E1BMR3", "url": "https://omabrowser.org/oma/group/E1BMR3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" }, { "name": "negative regulation of cellular senescence", "id": "GO:2000773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000773", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" }, { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "E1BMR3", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1007, "end_pos": 1009, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 740, "end_pos": 742, "annotation": "n_glycosylation_sequon" }, { "start_pos": 992, "end_pos": 994, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMR3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1068, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMR3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMR3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 801, "end_pos": 908, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BMR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" }, { "id": "SM01368", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01368" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Retinoblastoma-associated protein A-box", "eco_id": "ECO_0000259", "start_pos": 385, "end_pos": 578, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BMR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" }, { "id": "SM01369", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01369" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Retinoblastoma-associated protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 952, "end_pos": 1068, "start_aa": "Ser", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BMR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR3" }, { "id": "SM01367", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01367" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Retinoblastoma-associated protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 212, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1007, "end_pos": 1009 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 693, "end_pos": 695 }, { "start_pos": 740, "end_pos": 742 }, { "start_pos": 992, "end_pos": 994 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM76-1", "uniprot_ac": "E1BM76", "uniprot_id": "E1BM76_BOVIN", "mass": { "chemical_mass": 59251.0, "monoisotopic_mass": 59251.0 }, "refseq": { "ac": "NP_001179387", "name": "cysteine/serine-rich nuclear protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179387" }, "gene_names": [ { "name": "CSRNP2", "type": "recommended", "evidence": [ { "id": "E1BM76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM76" } ] }, { "name": "CSRNP2", "type": "synonym", "evidence": [ { "id": "NP_001179387", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179387" } ] } ], "protein_names": [ { "name": "Cysteine and serine rich nuclear protein 2", "type": "synonym", "evidence": [ { "id": "E1BM76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM76/entry#names_and_taxonomy" } ] }, { "name": "cysteine/serine-rich nuclear protein 2", "type": "synonym", "evidence": [ { "id": "NP_001179387", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179387" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM76", "url": "https://www.uniprot.org/uniprotkb/E1BM76" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CSRNP2", "url": "https://www.uniprot.org/uniprotkb/E1BM76", "locus": { "chromosome": "5", "start_pos": 28684721, "end_pos": 28671342, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010928", "url": "https://www.ensembl.org/id/ENSBTAG00000010928" } ] } } ], "crossref": [ { "id": "E1BM76", "url": "https://alphafold.ebi.ac.uk/entry/E1BM76", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010928", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010928", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "516929", "url": "https://www.ncbi.nlm.nih.gov/gene/516929", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516929", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516929", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PFRTDHE", "url": "https://omabrowser.org/oma/group/PFRTDHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM76", "url": "https://www.orthodb.org/?gene=E1BM76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13580", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13580", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13580:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13580:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16019", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16019", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179387", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179387", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TM70", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TM70-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM76", "url": "https://www.uniprot.org/uniprotkb/E1BM76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM76-1", "url": "https://www.uniprot.org/uniprotkb/E1BM76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAFTGSGLKRKFDDVDVGSSVSNSDDEISSSDSADSCDSLNPPTAASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPPAPDEEPSPTTSCSLAAAQGAETQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSGIESLGVCILEEPLAVPEELCPGLTAPILIQAQLPPGSSVLCFAENSDHPTASAVNNPSYLNSGPLVYYQVEQRPVLGVKGEPGTEEGPPSFPKEKDLNVFSLPVTSLVACGPTDPAALCKSEVGKTSTLEALVPEDCNPEEPGSEDCRPSWSPSSLPMCTDREEGCAVEKTAPQSADRPPEEPALELPLAV", "length": 543, "header": "tr|E1BM76-1|E1BM76_BOVIN Isoform 1 of Cysteine and serine rich nuclear protein 2 OS=Bos taurus OX=9913 GN=CSRNP2 PE=3 SV=3 CANONICAL=E1BM76-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TM70-1", "url": "https://www.uniprot.org/uniprotkb/E1BM76/entry#A0AAA9TM70-1", "sequence": { "sequence": "MSCSFQFKNPNAPGYLLVSRGFGADVVGSPKETPLKPMDAFTGSGLKRKFDDVDVGSSVSNSDDEISSSDSADSCDSLNPPTAASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPPAPDEEPSPTTSCSLAAAQGAETQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSGIESLGVCILEEPLAVPEELCPGLTAPILIQAQLPPGSSVLCFAENSDHPTASAVNNPSYLNSGPLVYYQVEQRPVLGVKGEPGTEEGPPSFPKEKDLNVFSLPVTSLVACGPTDPAALCKSEVGKTSTLEALVPEDCNPEEPGSEDCRPSWSPSSLPMCTDREEGCAVEKTAPQSADRPPEEPALELPLAV", "length": 580, "header": "tr|A0AAA9TM70-1|E1BM76_BOVIN Computationally mapped isoform of Cysteine and serine rich nuclear protein 2 OS=Bos taurus OX=9913 GN=CSRNP2 PE=3 SV=1 CANONICAL=E1BM76-1" }, "locus": { "chromosome": "5", "start_pos": 28684622, "end_pos": 28672371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115953.2", "url": "https://www.ensembl.org/id/ENSBTAT00000115953.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099567.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099567.1" } ] } }, { "isoform_ac": "E1BM76-1", "url": "https://www.uniprot.org/uniprotkb/E1BM76/entry#E1BM76-1", "sequence": { "sequence": "MDAFTGSGLKRKFDDVDVGSSVSNSDDEISSSDSADSCDSLNPPTAASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPPAPDEEPSPTTSCSLAAAQGAETQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSGIESLGVCILEEPLAVPEELCPGLTAPILIQAQLPPGSSVLCFAENSDHPTASAVNNPSYLNSGPLVYYQVEQRPVLGVKGEPGTEEGPPSFPKEKDLNVFSLPVTSLVACGPTDPAALCKSEVGKTSTLEALVPEDCNPEEPGSEDCRPSWSPSSLPMCTDREEGCAVEKTAPQSADRPPEEPALELPLAV", "length": 543, "header": "tr|E1BM76-1|E1BM76_BOVIN Isoform 1 of Cysteine and serine rich nuclear protein 2 OS=Bos taurus OX=9913 GN=CSRNP2 PE=3 SV=3 CANONICAL=E1BM76-1" }, "locus": { "chromosome": "5", "start_pos": 28684622, "end_pos": 28677054, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014517.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014517.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014517.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014517.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 465, "start_aa": "Thr", "end_pos": 465, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr465", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:516929", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516929", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PNW1-1", "protein_name": "Cysteine and serine rich nuclear protein 2", "gene_name": "CSRNP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGAPLDTPHHRPHPTGPPPTHGVPELHAIPMDAIASGRLKRKFEDVDVGSPASNSDDEISNSDSADSCDSVNPSSSSGFIPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAPRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESEEAEGLTLEDISDDDIDVENVEVDDYFFLQPLPTKQRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELENKRQGARPGDEELQGSGAAWPPGAQPPETQDFQEFMAENETAVMHLQTAEELERLKAEEDSSGGSGVESVGVCILEEPLAVPEALCPGLAAPILIQAQLPPGSSVLCFADGAEQPAATQPYLNAAPLLYYQVEPRSVLGPKGESGAEECPKDTGTVPAAPTGPCSRAAPAPSKGEGAKGVGQEGAQSCAASLGPSAPREAPGSEQPPQGV", "length": 519 }, "evidence": [ { "id": "E1BM76", "url": "https://omabrowser.org/oma/group/E1BM76/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A1W4-1", "protein_name": "Cysteine and serine rich nuclear protein 2", "gene_name": "Csrnp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAFSGSGLKRKFDDVDVGSSVSNSDDEMSSSDSADSCDSLNPPTTASFTPTSILKRQKPLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPAAAEDEPLPGAQSSETQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSSMESLGVCILEEPLAVPQELCPGLAAPILIQAQLPPGSSVLCFTENSEHPAASPMSSPSYLNSGPLVYYQVEQRPVVGVKAESGSEEGTASFPKEKDLSVFSLPVTSLVACSPSDSAALCKPEVGKAPSLNKLLPDDCNRKEPEREDFHPSWSPSSLPFRTDNEEGCGVQNSQQSEDRTPEDSALELPLAV", "length": 535 }, "evidence": [ { "id": "E1BM76", "url": "https://omabrowser.org/oma/group/E1BM76/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGQ2-1", "protein_name": "Cysteine/serine-rich nuclear protein 2", "gene_name": "Csrnp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAFSGSGLKRKFDDVDVGSSVSNSDDEMSSSDSADSCDSLNPPTTASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPAAEEEPLPGAQSSQTQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSSMESLGVCILEEPLAVPQELCPGLAAPILIQAQLPPGSSVLCFTENSEHPAASPMSSPSYLNSGPLVYYQVEQRPVVGVKAESGSEEGPASFPKEKDLSVFSLPVTSLVACGPSASAALCKPEVGKTSSLNKLLPEDCGLKEPESEDLHPSWSPSSLPFRTDNEEGCGVQNSQQSEDRTSEDSALELPLAV", "length": 534 }, "evidence": [ { "id": "E1BM76", "url": "https://omabrowser.org/oma/group/E1BM76/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H175-1", "protein_name": "Cysteine/serine-rich nuclear protein 2", "gene_name": "CSRNP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAFTGSGLKRKFDDVDVGSSVSNSDDEISSSDSADSCDSLNPPTTASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPAAPDEEPSPTASCSLTGAQGSETQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSSIESLGVCILEEPLAVPEELCPGLTAPILIQAQLPPGSSVLCFTENSDHPTASTVNSPSYLNSGPLVYYQVEQRPVLGVKGEPGTEEGSASFPKEKDLNVFSLPVTSLVACSSTDPAALCKSEVGKTPTLEALLPEDCNPEEPENEDFHPSWSPSSLPFRTDNEEGCGMVKTSQQNEDRPPEDSSLELPLAV", "length": 543 }, "evidence": [ { "id": "E1BM76", "url": "https://omabrowser.org/oma/group/E1BM76/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BM76", "url": "https://www.uniprot.org/uniprotkb/E1BM76" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BM76", "url": "https://www.uniprot.org/uniprotkb/E1BM76" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1BM76", "url": "https://www.uniprot.org/uniprotkb/E1BM76" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BM76", "url": "https://www.uniprot.org/uniprotkb/E1BM76" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "E1BM76", "url": "https://www.uniprot.org/uniprotkb/E1BM76" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BM76", "url": "https://www.uniprot.org/uniprotkb/E1BM76" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "E1BM76", "url": "https://www.uniprot.org/uniprotkb/E1BM76" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BM76", "url": "https://www.uniprot.org/uniprotkb/E1BM76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM76-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 543, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM76-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM76" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM76" }, { "id": "PF16019", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16019" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cysteine/serine-rich nuclear protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 279, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 465 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 320, "end_pos": 322 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLU0-1", "uniprot_ac": "E1BLU0", "uniprot_id": "E1BLU0_BOVIN", "mass": { "chemical_mass": 29200.0, "monoisotopic_mass": 29200.0 }, "refseq": { "ac": "XP_002695803", "name": "neuferricin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695803" }, "gene_names": [ { "name": "CYB5D2", "type": "recommended", "evidence": [ { "id": "E1BLU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLU0" } ] }, { "name": "CYB5D2", "type": "synonym", "evidence": [ { "id": "XP_002695803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695803" } ] } ], "protein_names": [ { "name": "Membrane-associated progesterone receptor component 1", "type": "recommended", "evidence": [ { "id": "E1BLU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLU0/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome b5 domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "E1BLU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLU0/entry#names_and_taxonomy" } ] }, { "name": "Neuferricin", "type": "synonym", "evidence": [ { "id": "E1BLU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLU0/entry#names_and_taxonomy" } ] }, { "name": "neuferricin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002695803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695803" } ] } ], "function": [ { "annotation": "Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. Intracellular heme chaperone. Regulates heme synthesis via interactions with FECH and acts as a heme donor for at least some hemoproteins. Forms a ternary complex with TMEM97 receptor and low density lipid receptor/LDLR, which increases LDLR-mediated LDL lipoprotein internalization.", "evidence": [ { "database": "UniProtKB", "id": "E1BLU0", "url": "https://www.uniprot.org/uniprotkb/E1BLU0#function" }, { "database": "UniProtKB", "id": "ARBA00053089", "url": "https://www.uniprot.org/uniprotkb/ARBA00053089#function" } ] }, { "annotation": "Heme-binding protein which promotes neuronal but not astrocyte differentiation.", "evidence": [ { "database": "UniProtKB", "id": "E1BLU0", "url": "https://www.uniprot.org/uniprotkb/E1BLU0#function" }, { "database": "UniProtKB", "id": "ARBA00037690", "url": "https://www.uniprot.org/uniprotkb/ARBA00037690#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLU0", "url": "https://www.uniprot.org/uniprotkb/E1BLU0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CYB5D2", "url": "https://www.uniprot.org/uniprotkb/E1BLU0", "locus": { "chromosome": "19", "start_pos": 24717947, "end_pos": 24711006, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016319", "url": "https://www.ensembl.org/id/ENSBTAG00000016319" } ] } } ], "crossref": [ { "id": "E1BLU0", "url": "https://alphafold.ebi.ac.uk/entry/E1BLU0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016319", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016319", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515356", "url": "https://www.ncbi.nlm.nih.gov/gene/515356", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001199", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001199", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515356", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515356", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHKHYGP", "url": "https://omabrowser.org/oma/group/GHKHYGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BLU0", "url": "https://www.orthodb.org/?gene=E1BLU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10281", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10281", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10281:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10281:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00173", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00173", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002695803", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695803", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TPM5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLU0", "url": "https://www.uniprot.org/uniprotkb/E1BLU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLU0-1", "url": "https://www.uniprot.org/uniprotkb/E1BLU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGLGGRGLWLGPAVAVAAAMAAWLMGWWSPRADFRLFIPEELARYRGRPGDPGLYLALLGRVYDVSSGRRHYEPGAHYSGFAGRDASRAFVTGDYSEAGLVDDVSDLSFSEMLTLQNWLSFYEKNYKFIGRVIGRFYGEDGLPTPELTQAEAMMTKGLEADRQELIEKQRFPPCNAEWSFIRGSRFWCSQQSGGVSRDWIGVPRKLFKPGVKPHCVCVRTTGPPSDQSPENPTHRNRGDLDHPNLGEYPGCPPLAITCSVPL", "length": 263, "header": "tr|E1BLU0-1|E1BLU0_BOVIN Isoform 1 of Membrane-associated progesterone receptor component 1 OS=Bos taurus OX=9913 GN=CYB5D2 PE=3 SV=3 CANONICAL=E1BLU0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TPM5-1", "url": "https://www.uniprot.org/uniprotkb/E1BLU0/entry#A0AAA9TPM5-1", "sequence": { "sequence": "MLLRPVLLWTCVFSSRVCIPRRRIAESYGRDASRAFVTGDYSEAGLVDDVSDLSFSEMLTLQNWLSFYEKNYKFIGRVIGRFYGEDGLPTPELTQAEAMMTKGLEADRQELIEKQRFPPCNAEWSFIRGSRFWCSQQSGGVSRDWIGVPRKLFKPGVKPHCVCVRTTGPPSDQSPENPTHRNRGDLDHPNLGEYPGCPPLAITCSVPL", "length": 208, "header": "tr|A0AAA9TPM5-1|E1BLU0_BOVIN Computationally mapped isoform of Membrane-associated progesterone receptor component 1 OS=Bos taurus OX=9913 GN=CYB5D2 PE=3 SV=1 CANONICAL=E1BLU0-1" }, "locus": { "chromosome": "19", "start_pos": 24716943, "end_pos": 24713661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130267.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130267.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098323.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098323.1" } ] } }, { "isoform_ac": "E1BLU0-1", "url": "https://www.uniprot.org/uniprotkb/E1BLU0/entry#E1BLU0-1", "sequence": { "sequence": "MPGLGGRGLWLGPAVAVAAAMAAWLMGWWSPRADFRLFIPEELARYRGRPGDPGLYLALLGRVYDVSSGRRHYEPGAHYSGFAGRDASRAFVTGDYSEAGLVDDVSDLSFSEMLTLQNWLSFYEKNYKFIGRVIGRFYGEDGLPTPELTQAEAMMTKGLEADRQELIEKQRFPPCNAEWSFIRGSRFWCSQQSGGVSRDWIGVPRKLFKPGVKPHCVCVRTTGPPSDQSPENPTHRNRGDLDHPNLGEYPGCPPLAITCSVPL", "length": 263, "header": "tr|E1BLU0-1|E1BLU0_BOVIN Isoform 1 of Membrane-associated progesterone receptor component 1 OS=Bos taurus OX=9913 GN=CYB5D2 PE=3 SV=3 CANONICAL=E1BLU0-1" }, "locus": { "chromosome": "19", "start_pos": 24716943, "end_pos": 24711205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021708.8", "url": "https://www.ensembl.org/id/ENSBTAT00000021708.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021708.6", "url": "https://www.ensembl.org/id/ENSBTAP00000021708.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515356", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515356", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B291-1", "protein_name": "Membrane-associated progesterone receptor component 1", "gene_name": "CYB5D2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPRLGGRGLWLGLAAAAVAAMIARLTGWWSPRADFRLFIPEELARYRGRPGDPGLYLALLGRVYDVSSGRRHYEPGAPYSGFAGRDASRAFVTGDYSETGLVDDVSDLSFSEMLTLQNWLSFYEKNYEFIGRVSGRFYGQDGLPTPELTRTEAMIARGVQANKQDLEEKQRFPPCNAEWSSARGSRLWCSPKSGGVSRDWTGVPRKLFKPGAKEPHCVCVKTTGAPSDQTPDSPPHRNRGDLDHPSLAEYPGCPPLATSCSLPL", "length": 264 }, "evidence": [ { "id": "E1BLU0", "url": "https://omabrowser.org/oma/group/E1BLU0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2CES0-1", "protein_name": "Neuferricin", "gene_name": "cyb5d2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKYLVALISMVLAVWTVPEWLTFPIYGNVVTVLESWLRQRVSEVSASSPGLLLTKEQLSLYNGGKNSKGLYLAILGQVFDVEKGRKHYGPGGGYHFFTGKDASRAFITGDFTEAGLSNDVSDFSESQIVALYDWLSFYQRDYTPVGKLIGRFYTETGQPTDALLHVEAFLSDGLKKKAQAQSEMQLYPSCNSEWSEASGGRVWCSTMSGGIHRDWVGVPRMLFTPGSGHSRCVCIRLSDPVHSENRNLREYTDCPPRAESCQIAKD", "length": 267 }, "evidence": [ { "id": "E1BLU0", "url": "https://omabrowser.org/oma/group/E1BLU0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2HIW2-1", "protein_name": "Membrane-associated progesterone-binding protein 4", "gene_name": "MAPR4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIPARRFLLSPFVGVTFIVVLVSLYFRSSFKSPQHQYQKRLFSAEELALYNGTDETLPILLGILGSVFDVTKGKFHYGSGGGYNHFAGRDASRAFVSGNFTGDGLTDSLQGLSSSEVKSIVDWRGFYSRTYTPVGKLVGRYYDSQGNPTKHLKGAEAKASRGAQLMEKQKTEEAKQSNCNSRWSQDEGGEVWCDVGVPRLVQRPLEIAITGSMSKRCACFEEDQLDQSGLEIYKDCEPLAKTCRV", "length": 245 }, "evidence": [ { "id": "E1BLU0", "url": "https://omabrowser.org/oma/group/E1BLU0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q5SSH8-1", "protein_name": "Neuferricin", "gene_name": "Cyb5d2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRICGLGVVLSLAVAAVAVMAVWLMDWWGPRPGIRLFLPEELARYRGGPGDPGLYLALLGRVYDVSSGRRHYEPGAHYSGFAGRDASRAFVTGDYSEAGLVDDINGLSSSEILTLHNWLSFYEKNYVFVGRLVGRFYRKDGLPTSELTQVEAMVTKGMEANEQEQREKQKFPPCNSEWSSAKGSRLWCSQKSGGVHRDWIGVPRKLYKPGAKEPHCVCVRTTGPPSDQQDNPRHSNHGDLDNPNLEEYTGCPPLATTCSFPL", "length": 263 }, "evidence": [ { "id": "E1BLU0", "url": "https://omabrowser.org/oma/group/E1BLU0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AY62-1", "protein_name": "Neuferricin", "gene_name": "Cyb5d2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRICGLGVVLSLAVAAAAVLAVWLMDWWGSHPSIRLFVPEELARYRGGPGDPGLYLALLGRVYDVSSGRKHYEPGAHYSGFAGRDASRAFVTGDYSEAGLVDDVNGLSSSEILTLHNWLSFYEKNYVFVGRLIGRFYGKDGLPTSELTQVEAMVTKGMEANEQEQREKQRFPPCNAEWSSAKGSRLWCSQKSGGVHRDWIGVPRKLYKPGAKEPHCVCVRTTGPPSDQQDNPRHSNRGDLDNPNLEEYTGCPPLAVTCFFPL", "length": 263 }, "evidence": [ { "id": "E1BLU0", "url": "https://omabrowser.org/oma/group/E1BLU0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WUJ1-1", "protein_name": "Neuferricin", "gene_name": "CYB5D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRCGGRGLLLGLAVAAAAVMAARLMGWWGPRAGFRLFIPEELSRYRGGPGDPGLYLALLGRVYDVSSGRRHYEPGSHYSGFAGRDASRAFVTGDCSEAGLVDDVSDLSAAEMLTLHNWLSFYEKNYVCVGRVTGRFYGEDGLPTPALTQVEAAITRGLEANKLQLQEKQTFPPCNAEWSSARGSRLWCSQKSGGVSRDWIGVPRKLYKPGAKEPRCVCVRTTGPPSGQMPDNPPHRNRGDLDHPNLAEYTGCPPLAITCSFPL", "length": 264 }, "evidence": [ { "id": "E1BLU0", "url": "https://omabrowser.org/oma/group/E1BLU0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W376-1", "protein_name": "Neuferricin homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFGLLRHLFKFQFLFVVAAVLGGIYHTEIRQFLRRQTDNYLDQAGQDASIPLAFQAGDDIGTLFTPAELAKFNGEEEGRPLYLALLGSVFDVSRGIKHYGSGCSYNFFVGRDASVSFISGDFETYDPETADDVLTLKPDDLIGLAGWRDFYQKDYVYKGRVIGRFYDEKGALTTYHHKFLELLEQARDAKRQVEELRARYPGCNIEWSEERGTRVWCTTTSGDGKERSWIGYPRKLYSRGNKSFQCACVPDAELDEIDAGGKVAHGDAMLKPYDNCEPQARECFYRV", "length": 287 }, "evidence": [ { "id": "E1BLU0", "url": "https://omabrowser.org/oma/group/E1BLU0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BLU0", "url": "https://www.uniprot.org/uniprotkb/E1BLU0" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "E1BLU0", "url": "https://www.uniprot.org/uniprotkb/E1BLU0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BLU0", "url": "https://www.uniprot.org/uniprotkb/E1BLU0" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "E1BLU0", "url": "https://www.uniprot.org/uniprotkb/E1BLU0" } ], "pmid": "" }, { "name": "smooth endoplasmic reticulum membrane", "id": "GO:0030868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030868", "evidence": [ { "database": "UniProtKB", "id": "E1BLU0", "url": "https://www.uniprot.org/uniprotkb/E1BLU0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "E1BLU0", "url": "https://www.uniprot.org/uniprotkb/E1BLU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLU0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 263, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLU0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLU0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLU0" }, { "id": "SM01117", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01117" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytochrome b5 heme-binding", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 134, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMK7-1", "uniprot_ac": "E1BMK7", "uniprot_id": "E1BMK7_BOVIN", "mass": { "chemical_mass": 71569.0, "monoisotopic_mass": 71569.0 }, "refseq": {}, "gene_names": [ { "name": "LOC107131333", "type": "recommended", "evidence": [ { "id": "E1BMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMK7" } ] } ], "protein_names": [ { "name": "GB1/RHD3-type G domain-containing protein", "type": "recommended", "evidence": [ { "id": "E1BMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMK7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMK7", "url": "https://www.uniprot.org/uniprotkb/E1BMK7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC107131333", "url": "https://www.uniprot.org/uniprotkb/E1BMK7", "locus": {} } ], "crossref": [ { "id": "E1BMK7", "url": "https://alphafold.ebi.ac.uk/entry/E1BMK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014857", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014857", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000038576", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038576", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01851", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01851", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1B824", "url": "https://www.orthodb.org/?gene=E1B824", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02263", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02263", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TPR0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPR0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B824", "url": "https://www.uniprot.org/uniprotkb/E1B824", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B824-1", "url": "https://www.uniprot.org/uniprotkb/E1B824-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMK7", "url": "https://www.uniprot.org/uniprotkb/E1BMK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMK7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGWDMMAPISLVENDNEQLSVNQEAIETLEKISQPVVVVAIVGLYRTGKSYLMNRLAGQKHGFPLGSTVQSKTKGIWMWCVPHPFKSDHTLVLLDTEGLGDVEKGDSKNDSWIFSLAVLLCSTFIYNSMSTINNQALEHLHYVTELTKLIKAKSSPSPDGEEDCTEFVTFFPDFIWAVRDFTLELKLNGHPITEDQYLENALKLTKGKNMKVQTSNLCKECIREFFPTRKCFVFDRPTNDKELLADIENVSEYQLNPKFQEQIKKFCSYIFTNAKTKTLREGVLVTGNWLVKLVVIYVDTINNGAVPCLENAVTSLAHLENSAAVQKAADHYSEKMTQQLSLPTDTFQELLEVHAACEKEAIAIFMERSFKDENQEFQKNLVEIIKNKKEDFVLQNEEASVKYCQVKLDEISKTLMESISAGIFSVPGGYELYRKAKERFEQDYHQVPRKGVKANEVLQSFLQSQAALEKSILQADKALTDGEKTVAEERARNEIAEKERELLKQKLQEQQQEMEAQKKSFQENIAQLTEKLEKEKENLLREMNMMLEHKMKVQETLLNEGFREKSELMSAEINQLKNMIDDTKEKDTPWVTKALDKFGDELTSILSSPAKLLGQIVKGIGSLFKK", "length": 628, "header": "tr|E1BMK7-1|E1BMK7_BOVIN Isoform 1 of GB1/RHD3-type G domain-containing protein OS=Bos taurus OX=9913 GN=LOC107131333 PE=3 SV=4 CANONICAL=E1BMK7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TPR0-1", "url": "https://www.uniprot.org/uniprotkb/E1BMK7/entry#A0AAA9TPR0-1", "sequence": { "sequence": "MASGWDMMAPISLVENDNEQLSVNQEAIETLEKISQPVVVVAIVGLYRTGKSYLMNRLAGQNHGFPLGSTVQSKTKGIWMWCVPHPSKSEHILVLLDTEGLGDVEKGDSKNDSWIFALAVLLSSTFVYNSMNTINNDALEKLHYVTELTELIRAKSSPKMDGVRDSVEFASFFPDFIWTVRDFTLELKLNDDPITEDEYLENALKLIKGSHPNVKKANLPRECIRHFFPKRKCFVFDRPVNDRELLAHLDEVLESQLDPKFKEQSDTFCSYIFTHARTKILREGVKVTGKRLGTLVVTYVDAINSGGIPCLENAVTTLAHLENSAAMQKAADYYSEQMTQRLNLPTDTLQELLEVHTACEREATVVFMNQSFKDENQDFQKKLLEIIKNKKEGFLQQNEEASAKYCQTKLDQISKTLKESISAGSFSVPGGHKLYRKAMERLQQDYCHVPRKGVKTNEVLQNFLQSQVAIEISILQSDKALTDAAKAIAEKQARKEATERERELLIQKQYEQQQQMEAQDRSLRENIAQLREKLERERENFEKEKERLLEHTLKAQNDLLTEGFSRKAEEMKAEIKHLRNIIEKSKKDKASWISKTLDGLATEATAILSLPAKVIGWGLKGLSSLFK", "length": 627, "header": "tr|A0AAA9TPR0-1|E1BMK7_BOVIN Computationally mapped isoform of GB1/RHD3-type G domain-containing protein OS=Bos taurus OX=9913 GN=LOC107131333 PE=3 SV=1 CANONICAL=E1BMK7-1" }, "locus": { "chromosome": "3", "start_pos": 54062083, "end_pos": 54009526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110866.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110866.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100532.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100532.1" } ] } }, { "isoform_ac": "E1B824-1", "url": "https://www.uniprot.org/uniprotkb/E1BMK7/entry#E1B824-1", "sequence": { "sequence": "MASGWDMMAPISLVENDNEQLSVNQEAIETLEKISQPVVVVAIVGLYRTGKSYLMNRLAGQKHGFPLGSTVQSKTKGIWMWCVPHPFKSDHTLVLLDTEGLGDVEKGDSKNDSWIFSLAVLLCSTFIYNSMSTINNQALEHLHYVTELTKLIKAKSSPSPDGEEDCTEFVTFFPDFIWAVRDFTLELKLNGHPITEDQYLENALKLTKGKNMKVQTSNLCKECIREFFPTRKCFVFDRPTNDKELLADIENVSEYQLNPKFQEQIKKFCSYIFTNAKTKTLREGVLVTGNWLVKLVVIYVDTINNGAVPCLENAVTSLAHLENSAAVQKAADHYSEKMTQQLSLPTDTFQELLEVHAACEKEAIAIFMERSFKDENQEFQKNLVEIIKNKKEDFVLQNEEASVKYCQVKLDEISKTLMESISAGIFSVPGGYELYRKAKERFEQDYHQVPRKGVKANEVLQSFLQSQAALEKSILQADKALTDGEKTVAEERARNEIAEKERELLKQKLQEQQQEMEAQKKSFQENIAQLTEKLEKEKENLLREMNMMLEHKMKESLLGCQVTMASGPNMMDPICLVENKNAQLSVNQKALQILENISQPVVVVAIVGLYRTGKSYLMNRLAGQNHGFPLGSTVQSKTKGIWMWCVPHPSKSEHILVLLDTEGLGDVEKGDSKNDSWIFALAVLLSSTFVYNSMNTINNDALEKLHYVTELTELIRAKSSPKMDGVRDSVEFASFFPDFIWTVRDFTLELKLNDDPITEDEYLENALKLIKGSHPNVKKANLPRECIRHFFPKRKCFVFDRPVNDRELLAHLDEVLESQLDPKFKEQSDTFCSYIFTHARTKILREGVKVTGKRLGTLVVTYVDAINSGGIPCLENAVTTLAHLENSAAMQKAADYYSEQMTQRLNLPTDTLQELLEVHTACEREATVVFMNQSFKDENQDFQKKLLEIIKNKKEGFLQQNEEASAKYCQTKLDQISKTLKESISAGSFSVPGGHKLYRKAMERLQQDYCHVPRKGVKTNEVLQNFLQSQVAIEISILQSDKALTDAAKAIAEKQARKEATERERELLIQKQYEQQQQMEAQDRSLRENIAQLREKLERERENFEKEKERLLEHTLKAQNDLLTEGFSRKAEEMKAEIKHLRNIIEKSKKDKASWISKTLDGLATEATAILSLPAKVIGWGLKGLSSLFK", "length": 1190, "header": "tr|E1B824-1|E1BMK7_BOVIN Computationally mapped isoform of GB1/RHD3-type G domain-containing protein OS=Bos taurus OX=9913 GN=LOC107131333 PE=3 SV=3 CANONICAL=E1BMK7-1" }, "locus": { "chromosome": "3", "start_pos": 54062083, "end_pos": 54009526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053287.4", "url": "https://www.ensembl.org/id/ENSBTAT00000053287.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052286.3", "url": "https://www.ensembl.org/id/ENSBTAP00000052286.3" } ] } }, { "isoform_ac": "E1BMK7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMK7/entry#E1BMK7-1", "sequence": { "sequence": "MASGWDMMAPISLVENDNEQLSVNQEAIETLEKISQPVVVVAIVGLYRTGKSYLMNRLAGQKHGFPLGSTVQSKTKGIWMWCVPHPFKSDHTLVLLDTEGLGDVEKGDSKNDSWIFSLAVLLCSTFIYNSMSTINNQALEHLHYVTELTKLIKAKSSPSPDGEEDCTEFVTFFPDFIWAVRDFTLELKLNGHPITEDQYLENALKLTKGKNMKVQTSNLCKECIREFFPTRKCFVFDRPTNDKELLADIENVSEYQLNPKFQEQIKKFCSYIFTNAKTKTLREGVLVTGNWLVKLVVIYVDTINNGAVPCLENAVTSLAHLENSAAVQKAADHYSEKMTQQLSLPTDTFQELLEVHAACEKEAIAIFMERSFKDENQEFQKNLVEIIKNKKEDFVLQNEEASVKYCQVKLDEISKTLMESISAGIFSVPGGYELYRKAKERFEQDYHQVPRKGVKANEVLQSFLQSQAALEKSILQADKALTDGEKTVAEERARNEIAEKERELLKQKLQEQQQEMEAQKKSFQENIAQLTEKLEKEKENLLREMNMMLEHKMKVQETLLNEGFREKSELMSAEINQLKNMIDDTKEKDTPWVTKALDKFGDELTSILSSPAKLLGQIVKGIGSLFKK", "length": 628, "header": "tr|E1BMK7-1|E1BMK7_BOVIN Isoform 1 of GB1/RHD3-type G domain-containing protein OS=Bos taurus OX=9913 GN=LOC107131333 PE=3 SV=4 CANONICAL=E1BMK7-1" }, "locus": { "chromosome": "3", "start_pos": 54032200, "end_pos": 54009526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019785.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019785.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019785.7", "url": "https://www.ensembl.org/id/ENSBTAP00000019785.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "E1BMK7", "url": "https://www.uniprot.org/uniprotkb/E1BMK7" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "E1BMK7", "url": "https://www.uniprot.org/uniprotkb/E1BMK7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "E1BMK7", "url": "https://www.uniprot.org/uniprotkb/E1BMK7" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "E1BMK7", "url": "https://www.uniprot.org/uniprotkb/E1BMK7" } ], "pmid": "" }, { "name": "cellular response to type II interferon", "id": "GO:0071346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071346", "evidence": [ { "database": "UniProtKB", "id": "E1BMK7", "url": "https://www.uniprot.org/uniprotkb/E1BMK7" } ], "pmid": "" }, { "name": "defense response to protozoan", "id": "GO:0042832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042832", "evidence": [ { "database": "UniProtKB", "id": "E1BMK7", "url": "https://www.uniprot.org/uniprotkb/E1BMK7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "E1BMK7", "url": "https://www.uniprot.org/uniprotkb/E1BMK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMK7" }, { "id": "PS51715", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51715" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GB1/RHD3-type G", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 277, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 251, "end_pos": 253 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNI8-1", "uniprot_ac": "E1BNI8", "uniprot_id": "E1BNI8_BOVIN", "mass": { "chemical_mass": 60332.0, "monoisotopic_mass": 60332.0 }, "refseq": {}, "gene_names": [ { "name": "NT5DC2", "type": "recommended", "evidence": [ { "id": "E1BNI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNI8" } ] } ], "protein_names": [ { "name": "5'-nucleotidase domain containing 2", "type": "synonym", "evidence": [ { "id": "E1BNI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNI8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNI8", "url": "https://www.uniprot.org/uniprotkb/E1BNI8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NT5DC2", "url": "https://www.uniprot.org/uniprotkb/E1BNI8", "locus": { "chromosome": "22", "start_pos": 48344008, "end_pos": 48291464, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014784", "url": "https://www.ensembl.org/id/ENSBTAG00000014784" } ] } } ], "crossref": [ { "id": "E1BNI8", "url": "https://alphafold.ebi.ac.uk/entry/E1BNI8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014784", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014784", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07522", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07522", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR008380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514296", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514296", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWTHQPQ", "url": "https://omabrowser.org/oma/group/QWTHQPQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNI8", "url": "https://www.orthodb.org/?gene=E1BNI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12103:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12103:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05761", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05761", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TTU7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTU7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNI8", "url": "https://www.uniprot.org/uniprotkb/E1BNI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNI8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAGLRAAARRWVPRRDHGGPRAASSSPSCPGCGPPGPGAHCPGAPRSAPAPAPAGGAAEPSAHLWARYQDMRRLVHDLLPPEVCSLLNPAAIYANNEISLRDVEVYGFDYDYTLAQYSDTLHPEIFNAARDILVEHYKYPEGIRKYEYNPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLQPVPDEEVIELYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDHFLGHGLEFDQAHLYKDVTDAIRDVHVKGLMYQWIERDMEKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPSFFTDRRKPFRKLDEKGSLHWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLAAWMKERQELSLGASSAPSTTPPTSRGGWCASPTSTWPPSAACSTTAWTSPSTRAAPPCSTRRRSGWTSSAPAA", "length": 535, "header": "tr|E1BNI8-1|E1BNI8_BOVIN Isoform 1 of 5'-nucleotidase domain containing 2 OS=Bos taurus OX=9913 GN=NT5DC2 PE=3 SV=3 CANONICAL=E1BNI8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TTU7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNI8/entry#A0AAA9TTU7-1", "sequence": { "sequence": "MAGAGLRAAARRWVPRRDHGGPRAASSSPSCPGCGPPGPGAHCPGAPRSAPAPAPAGGAAEPSAHLWARYQDMRRLVHDLLPPEVCSLLNPAAIYANNEISLRDVEVYGFDYDYTLAQYSDTLHPEIFNAARDILVEHYKSLLMKIDAFHYVQLGTAYRGLQPVPDEEVIELYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDHFLGHGLEFDQAHLYKDVTDAIRDVHVKGLMYQWIERDMEKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPSFFTDRRKPFRKLDEKGSLHWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLAAWMKERQELRCVTKALFNAQFGSIFRTFHNPTYFSRRLVRFSDLYMASLSCLLNYRVDFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLSDMAHIR", "length": 533, "header": "tr|A0AAA9TTU7-1|E1BNI8_BOVIN Computationally mapped isoform of 5'-nucleotidase domain containing 2 OS=Bos taurus OX=9913 GN=NT5DC2 PE=3 SV=1 CANONICAL=E1BNI8-1" }, "locus": { "chromosome": "22", "start_pos": 48343004, "end_pos": 48291663, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101247.2", "url": "https://www.ensembl.org/id/ENSBTAT00000101247.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100800.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100800.1" } ] } }, { "isoform_ac": "E1BNI8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNI8/entry#E1BNI8-1", "sequence": { "sequence": "MAGAGLRAAARRWVPRRDHGGPRAASSSPSCPGCGPPGPGAHCPGAPRSAPAPAPAGGAAEPSAHLWARYQDMRRLVHDLLPPEVCSLLNPAAIYANNEISLRDVEVYGFDYDYTLAQYSDTLHPEIFNAARDILVEHYKYPEGIRKYEYNPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLQPVPDEEVIELYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDHFLGHGLEFDQAHLYKDVTDAIRDVHVKGLMYQWIERDMEKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPSFFTDRRKPFRKLDEKGSLHWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLAAWMKERQELSLGASSAPSTTPPTSRGGWCASPTSTWPPSAACSTTAWTSPSTRAAPPCSTRRRSGWTSSAPAA", "length": 535, "header": "tr|E1BNI8-1|E1BNI8_BOVIN Isoform 1 of 5'-nucleotidase domain containing 2 OS=Bos taurus OX=9913 GN=NT5DC2 PE=3 SV=3 CANONICAL=E1BNI8-1" }, "locus": { "chromosome": "22", "start_pos": 48342966, "end_pos": 48291663, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019665.8", "url": "https://www.ensembl.org/id/ENSBTAT00000019665.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019665.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019665.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514296", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514296", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2I3BR81-1", "protein_name": "5'-nucleotidase domain containing 2", "gene_name": "Nt5dc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGAGLRATARRLLLCRGHSGPRAASSSPSCPGCGPPGPGAHCPSTPRSAPADGADLSAHLWARYQDMRRLVHDLLPPEVCSLLNPAAIYANNEISLSDVEVYGFDYDYTLAQYADALHPEIFNAARDILIEHYKYPEGIRKYDYDPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLKPVPDDEVIDLYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDYFLGHGLEFDQVHLYKDVTDAIRDVHVKGLMYQWIEQDMEKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPNFFTDRRKPFRKLDEKGSLHWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLATWMKERQELRCITKALFNAQFGSIFRTFHNPTYFSRRLVRFSDLYMASLSCLLNYRVDFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLGDMAHIR", "length": 553 }, "evidence": [ { "id": "E1BNI8", "url": "https://omabrowser.org/oma/group/E1BNI8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8V1ABT7-1", "protein_name": "5'-nucleotidase domain containing 2", "gene_name": "NT5DC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MWGGTSPSLSVDVMRDPAVGRVLLLFSCKGQLSWSGKQKWTGLLLALLLALLLALLWLSQAEALFWSDKPQQLTYSHSCLSAERRLLVAISTTRSQSVASWRGVFGVCFVLDLLPPGVCNLLNPAAIYANNEISLGDVEIYGFDYDYTLAQYSNLLHSMIFNTARDILIEQFKYPEGLGKYDYIPGFAIRGLHYDVQKSLLMKIDAFHYVQLGTAYRGLKPVPDEEVIELYGGTQHIPLYQMSDFYGKGPSLKQFMDIFSLPEMTLLSSVIDYFITHGIEFDQVHLYKDISDAIRDVHVKGVMYKWIEKDMEQYILHGDEIYAVLNRLVNHKKKLFLITNSPFSFVDKGMKHMVGKNWRDLFDMVIVQADKPNFFTDRRKPFRKLDDNGSLQWDKINQLEKGKIYKEGNLFDFLRLTGWRGSKVLYFGDHLYSDLADLMLRHGWRTGAIVPELETEIRIINTEQYMHSLTWQQALTGLLERMQMYQDAESKQVLLEWMKERQEIRSLTKNLFNPQFGSIFRTFHNPTYFSRRLVRFSDIYMASISCLLNYDVNFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLEEMVHIR", "length": 591 }, "evidence": [ { "id": "E1BNI8", "url": "https://omabrowser.org/oma/group/E1BNI8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SIV9-1", "protein_name": "5'-nucleotidase domain containing 2", "gene_name": "NT5DC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGAGLRAAARRYLPRRDHGGPRAASSSPSCPGCGPPGPGVHCPGVPRSTPSPAPAGAAEPSAHLWARYQDMRRLVHDLLPPEVCSLLNPAAIYANNEISLQDVEVYGFDYDYTLAQYADTLHPEIFNAARDILIEHYKYPEGIRKYDYNPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLQPVPDEEVIDLYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDHFLGHGLEFDQAHLYKDVTDAIRDVHVKGLMYQWIEQDMEKYILRGEETFAVLNRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPSFFTDRRKPFRKLDEKGSLHWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLAAWMKERQELRCITKALFNAQFGSIFRTFHNPTYFSRRLVRFSDLYMASLSCLLNYRVDFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLGDMAHIR", "length": 557 }, "evidence": [ { "id": "E1BNI8", "url": "https://omabrowser.org/oma/group/E1BNI8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6Q0N3-1", "protein_name": "5'-nucleotidase domain-containing protein 2", "gene_name": "Nt5dc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGAGLRAAARRWLLCGGQGGPRAASSSPSCPGCGPPGPGAHCPSTPRSAPADGADLSAHLWARYQDMRRLVHDLLPPEVCSLLNPAAIYANNEISLSDVEVYGFDYDYTLAQYADALHPEIFSAARDILIEHYKYPEGIRKYDYDPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLQPVPDDEVVDLYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDYFLGHGLEFDQVHLYKDVTDAIRDVHVKGLMYQWIEQDMEKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPNFFTDRRKPFRKLDEKGSLHWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLATWMKERQELRCITKALFNAQFGSIFRTFHNPTYFSRRLVRFSDLYMASLSCLLNYSVDFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLGDMAHIR", "length": 553 }, "evidence": [ { "id": "E1BNI8", "url": "https://omabrowser.org/oma/group/E1BNI8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H857-1", "protein_name": "5'-nucleotidase domain-containing protein 2", "gene_name": "NT5DC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVESGSAQERGILLESLSTLLEKTTASHEGRAPGNRELTDLLPPEVCSLLNPAAIYANNEISLRDVEVYGFDYDYTLAQYADALHPEIFSTARDILIEHYKYPEGIRKYDYNPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLQPVPDEEVIELYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDYFLGHSLEFDQAHLYKDVTDAIRDVHVKGLMYQWIEQDMEKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPSFFTDRRKPFRKLDEKGSLQWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLAAWMKERQELRCITKALFNAQFGSIFRTFHNPTYFSRRLVRFSDLYMASLSCLLNYRVDFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLGDMAHIR", "length": 520 }, "evidence": [ { "id": "E1BNI8", "url": "https://omabrowser.org/oma/group/E1BNI8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1BNI8", "url": "https://www.uniprot.org/uniprotkb/E1BNI8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BNI8", "url": "https://www.uniprot.org/uniprotkb/E1BNI8" } ], "pmid": "" }, { "name": "5'-nucleotidase activity", "id": "GO:0008253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008253", "evidence": [ { "database": "UniProtKB", "id": "E1BNI8", "url": "https://www.uniprot.org/uniprotkb/E1BNI8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNI8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 535, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNI8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNI8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0AAA9TTU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTU7#function" }, { "id": "A0AAA9TTU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTU7" }, { "id": "PIRSR017434-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR017434-2" } ], "binding_site_uniprot": 111, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 111, "end_pos": 111, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0AAA9TTU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTU7#function" }, { "id": "A0AAA9TTU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTU7" }, { "id": "PIRSR017434-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR017434-2" } ], "binding_site_uniprot": 371, "amino_acid": "Ile", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 371, "end_pos": 371, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM39-1", "uniprot_ac": "E1BM39", "uniprot_id": "E1BM39_BOVIN", "mass": { "chemical_mass": 280572.0, "monoisotopic_mass": 280572.0 }, "refseq": { "ac": "XP_010816562", "name": "cullin-9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816562" }, "gene_names": [ { "name": "CUL9", "type": "recommended", "evidence": [ { "id": "E1BM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ] }, { "name": "CUL9", "type": "synonym", "evidence": [ { "id": "XP_010816562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816562" } ] } ], "protein_names": [ { "name": "Cullin-9", "type": "recommended", "evidence": [ { "id": "E1BM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM39/entry#names_and_taxonomy" } ] }, { "name": "cullin-9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010816562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816562" } ] }, { "name": "p53-associated parkin-like cytoplasmic protein", "type": "synonym", "evidence": [ { "id": "E1BM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM39/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CUL9", "url": "https://www.uniprot.org/uniprotkb/E1BM39", "locus": { "chromosome": "23", "start_pos": 16822967, "end_pos": 16784390, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019908", "url": "https://www.ensembl.org/id/ENSBTAG00000019908" } ] } } ], "crossref": [ { "id": "ENSBTAG00000019908", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019908", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16624", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16624", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20347", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20347", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20359", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20359", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540077", "url": "https://www.ncbi.nlm.nih.gov/gene/540077", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045093", "url": 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Classification" ] }, { "id": "IPR060082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540077", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540077", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KPWKPNH", "url": "https://omabrowser.org/oma/group/KPWKPNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM39", "url": "https://www.orthodb.org/?gene=E1BM39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22771:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22771:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26718", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26718", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010816562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816562", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TX57", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TX57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TX57-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TX57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWD1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWD1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM39-1", "url": "https://www.uniprot.org/uniprotkb/E1BM39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGERRTGDLTVPLGPRLQAYPEELLRQRPGQDGHPEYLIRWSVLKCGEVGRAGVEEGKAEHILMWLSAPEVYASCPTLLGERALSKGPQHETAGGPASFPRDPGSLDDVAMGEMEADVRALVRRAARQLAEGGTSSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEPQIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHCMAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNNSPEQGAGDRGSPTSREDLGREKSRGQRELEFSMAVGNLISELVRSMGWARNLSQQGTLPPRPTRSIFQPSISGPSLLLPTIVAPPRRQGRAFRQRAEFSSLSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWQSTSRTYWVHWHMLEILGPEETTEDTASAAAEEGAGAAVPGTALPSWDWKPVDGLYSLPYLQPEPQKNEKLGYLTQAEWWELLFFIRKLDICEQQSIYQSLRENLDESLGEKAVGEISVPVAMAESLLQVLRNRFEGSTLSDLLNSQIYTKYGLQPDALSGSSSSQNHSSTPDPEEESKSEATFSEEETESPNVKAQPLKAEAEPVKGKTELPMAQSDSQLFNQLLVTEGMALPAGMKEAAGEMIRALRGPGPRSSLDQYVAAVVATVQISSLDTSLQLSALCALSQAVEEVTERDHPLVHPDRFLREKLVKTLVELLTNQVGEKMVVVLALRLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAIASSSEISTSVTSQDSIHPLFDAQMTREIFASIDSATRPDSESLLLALPAAVILMLNTEGCSSAVRNGLLLLNLLLCNHHTLGDQIITRELRDTLFRHSGIAPGTEPMPTTRTILTMLLNRYSKPPGSPERSAAPETPSAQGQEGSPELLIRSLVGGPSAELLLDLERVLCREGGPGGAVRPLLKRLQQESQPFLLFLWTLDAPGPNKTLLLTALRVMTQLLDHTEAMVLPWHEVLEPCLNCLNGPGSDSEIVQELLCFLYRLASTHKDYAVVLCCLGAKDALTKVLEKHSAQLLLACELRDLVTECEKHAQLYSNLTSSILAGCIQMVLGQIEDHRRTYRPINIPFFDVFLRHLCQGSSVEVKEDKCWEKLEVSSNPHRASKLTDRNPKTYWESNGSTGSHFITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSASCINTELNTVNVMPSASRVVLLENLSRVWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIWAQAWSRDIAEDRKRLLQLCPRLNRVLRHEQNFADRFLPDEEAAQALGKTCWEALVSPLVQNITCPDAEGVSSLGWLLDQYLEQRESSRNPRGRAASFASRVRRLCHLLVHVEPPPGPSPEPSARPPSKSSKARDRSPGPSPVLPSSSLRNITQCWLSVVQEQVSTFLAAAWRAPDFVPRYCKLYERLQRAGLELFGPRAAFTLALRSGFSGALLQQSFLTTAHMSEQFARHIDQQIQSGLMGGTPGVEVLGRLQWHLEPIMVLSGLELATTFEHFYQHYMADRLLSLGSSWLEGAVLEQIGLCFPNRLPQQMLRSLSTSEELQRQFHVYQLQQLDKLFLEQEDEEEQGLEEEEEEEEAEKELFIEDPSPTVSVLVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYNQSQNHPALDVGPHRRLQWTWLGRAELQFADQTLHVSTVQMWLLLHFNQTEEVSVEALLKNSGLSPELLLQALLPLTSDSGPLTLQEGQDFPPRGVLRLREPGLQPRGEALWLLPPQTYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWHKGPNPPGSLGRAIAGGVACTSTDVLSCILHLLGQGYVERRDDWPQILTYATPEPTGPCRGQAEIPFFGSQTSETSKISPEAVAALASLQLPAGRTMSPREVEGLMEQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSDDPEPLLLAAGLRVPQAQAAPARPDHCPVCVSPLAPDRDLPALCCQHSCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCANLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFSCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLTKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQARDFAVNLRNRVSAIHEVPPPKSFTFLSDACRGLEQARKVLAYACVYSFYNQDTEHMDVVEQQIEALELHTNALQILLEETLLHCRDLASSLRLLRAEHLNTGLELLRRIQERLLAILQHSTQDFRVGLQSPSSESREAKGPNVPGSQPQGSSELEEEEEDEEPEWQQDEFEEELDNDSFSYDEESENLDRETFFFGDEDDDEEDDEGYD", "length": 2518, "header": "tr|E1BM39-1|E1BM39_BOVIN Isoform 1 of Cullin-9 OS=Bos taurus OX=9913 GN=CUL9 PE=3 SV=3 CANONICAL=E1BM39-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TX57-1", "url": "https://www.uniprot.org/uniprotkb/E1BM39/entry#A0AAA9TX57-1", "sequence": { "sequence": "MVGERRTGDLTVPLGPRLQAYPEELLRQRPGQDGHPEYLIRWSVLKCGEVGRAGVEEGKAEHILMWLSAPEVYASCPTLLGERALSKGPQHETAGGPASFPRDPGSLDDVAMGEMEADVRALVRRAARQLAEGGTSSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEPQIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHCMAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNNSPEQGAGDRGSPTSREDLGREKSRGQRELEFSMAVGNLISELVRSMGWARNLSQQGTLPPRPTRSIFQPSISGPSLLLPTIVAPPRRQGRAFRQRAEFSSLSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWQSTSRTYWVHWHMLEILGPEETTEDTASAAAEEGAGAAVPGTALPSWDWKPVDGLYSLPYLQPEPQKNEKLGYLTQAEWWELLFFIRKLDICEQQSIYQSLRENLDESLGEKAVGEISVPVAMAESLLQVLRNRFEGSTLSDLLNSQIYTKYGLQPDALSGSSSSQNHSSTPDPEEESKSEATFSEEETESPNVKAQPLKAEAEPVKGKTELPMAQSDSQLFNQLLVTEGMALPAGMKEAAGEMIRALRGPGPRSSLDQYVAAVVATVQISSLDTSLQLSALCALSQAVEEVTERDHPLVHPDRFLREKLVKTLVELLTNQVGEKMVVVLALRLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAIASSSEISTSVTSQDSIHPLFDAQMTREIFASIDSATRPDSESLLLALPAAVILMLNTEGCSSAVRNGLLLLNLLLCNHHTLGDQIITRELRDTLFRHSGIAPGTEPMPTTRTILTMLLNRYSKPPGSPERSAAPETPSAQGQEGSPELLIRSLVGGPSAELLLDLERVLCREGGPGGAVRPLLKRLQQESQPFLLFLWTLDAPGPNKTLLLTALRVMTQLLDHTEAMVLPWHEVLEPCLNCLNGPGSDSEIVQELLCFLYRLASTHKDYAVVLCCLGAKDALTKVLEKHSAQLLLACELRDLVTECEKHAQLYSNLTSSILAGCIQMVLGQIEDHRRTYRPINIPFFDVFLRHLCQGSSVEVKEDKCWEKLEVSSNPHRASKLTDRNPKTYWESNGSTGSHFITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSASCINTELNTVNVMPSASRVVLLENLSRVWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIWAQAWSRDIAEDRKRLLQLCPRLNRVLRHEQNFADRFLPDEEAAQALGKTCWEALVSPLVQNITCPDAEGVSSLGWLLDQYLEQRESSRNPRGRAASFASRVRRLCHLLVHVEPPPGPSPEPSARPPSKSSKARDRSPGPSPVLPSSSLRNITQCWLSVVQEQMSEQFARHIDQQIQSGLMGGTPGVEVLGRLQWHLEPIMVLSGLELATTFEHFYQHYMADRLLSLGSSWLEGAVLEQIGLCFPNRLPQQMLRSLSTSEELQRQFHVYQLQQLDKLFLEQEDEEEQGLEEEEEEEEAEKELFIEDPSPTVSVLVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYNQSQNHPALDVGPHRRLQWTWLGRAELQFADQTLHVSTVQMWLLLHFNQTEEVSVEALLKNSGLSPELLLQALLPLTSDSGPLTLQEGQDFPPRGVLRLREPGLQPRGEALWLLPPQTYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWHKGPNPPGSLGRAIAGGVACTSTDVLSCILHLLGQGYVERRDDWPQILTYATPEPTGPCRGQAEIPFFGSQTSETSKISPEAVAALASLQLPAGRTMSPREVEGLMEQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSDDPEPLLLAAGLRVPQAQAAPARPDHCPVCVSPLAPDRDLPALCCQHSCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCANLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFSCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLTKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQARDFAVNLRNRVSAIHEVPPPKSFTFLSDACRGLEQARKVLAYACVYSFYNQDTEHMDVVEQQIEALELHTNALQILLEETLLHCRDLASSLRLLRAEHLNTGLELLRRIQERLLAILQHSTQDFRVGLQSPSSESREAKGPNVPGSQPQGSSELEEEEEDEEPEWQQDEFEEELDNDSFSYDEESENLDRETFFFGDEDDDEEDDEGYD", "length": 2457, "header": "tr|A0AAA9TX57-1|E1BM39_BOVIN Computationally mapped isoform of Cullin-9 OS=Bos taurus OX=9913 GN=CUL9 PE=3 SV=1 CANONICAL=E1BM39-1" }, "locus": { "chromosome": "23", "start_pos": 16821963, "end_pos": 16786304, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135001.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135001.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103235.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103235.1" } ] } }, { "isoform_ac": "A0ABI0NWD1-1", "url": "https://www.uniprot.org/uniprotkb/E1BM39/entry#A0ABI0NWD1-1", "sequence": { "sequence": "MVGERRTGDLTVPLGPRLQAYPEELLRQRPGQDGHPEYLIRWSVLKCGEVGRAGVEEGKAEHILMWLSAPEVYASCPTLLGERALSKGPQHETAGGPASFPRDPGSLDDVAMGEMEADVRALVRRAARQLAEGGTSSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEPQIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHCMAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNNSPEQGAGDRGSPTSREDLGREKSRGQRELEFSMAVGNLISELVRSMGWARNLSQQGTLPPRPTRSIFQPSISGPSLLLPTIVAPPRRQGRAFRQRAEFSSLSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWQSTSRTYWVHWHMLEILGPEETTEDTASAAAEEGAGAAVPGTALPSWDWKPVDGLYSLPYLQPEPQKNEKLGYLTQAEWWELLFFIRKLDICEQQSIYQSLRENLDESLGEKAVGEISVPVAMAESLLQVLRNRFEGSTLSDLLNSQIYTKYGLQPDALSGSSSSQNHSSTPDPEEESKSEATFSEEETESPNVKAQPLKAEAEPVKGKTELPMAQSDSQLFNQLLVTEGMALPAGMKEAAGEMIRALRGPGPRSSLDQYVAAVVATVQISSLDTSLQLSALCALSQAVEEVTERDHPLVHPDRFLREKLVKTLVELLTNQVGEKMVVVLALRLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAIASSSEISTSVTSQDSIHPLFDAQMTREIFASIDSATRPDSESLLLALPAAVILMLNTEGCSSAVRNGLLLLNLLLCNHHTLGDQIITRELRDTLFRHSGIAPGTEPMPTTRTILTMLLNRYSKPPGSPERSAAPETPSAQGQEGSPELLIRSLVGGPSAELLLDLERVLCREGGPGGAVRPLLKRLQQESQPFLLFLWTLDAPGPNKTLLLTALRVMTQLLDHTEAMVLPWHEVLEPCLNCLNGPGSDSEIVQELLCFLYRLASTHKDYAVVLCCLGAKDALTKVLEKHSAQLLLACELRDLVTECEKHAQLYSNLTSSILAGCIQMVLGQIEDHRRTYRPINIPFFDVFLRHLCQGSSVEVKEDKCWEKLEVSSNPHRASKLTDRNPKTYWESNGSTGSHFITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSASCINTELNTVNVMPSASRVVLLENLSRVWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIWAQAWSRDIAEDRKRLLQLCPRLNRVLRHEQNFADRFLPDEEAAQALGKTCWEALVSPLVQNITCPDAEGVSSLGWLLDQYLEQRESSRNPRGRAASFASRVRRLCHLLVHVEPPPGPSPEPSARPPSKSSKARDRSPGPSPVLPSSSLRNITQCWLSVVQEQVSTFLAAAWRAPDFVPRYCKLYERLQRAGLELFGPRAAFTLALRSGFSGALLQQSFLTTAHMSEQFARHIDQQIQSGLMGGTPGVEVLGRLQWHLEPIMVLSGLELATTFEHFYQHYMADRLLSLGSSWLEGAVLEQIGLCFPNRLPQQMLRSLSTSEELQRQFHVYQLQQLDKLFLEQEDEEEQGLEEEEEEEEAEKELFIEDPSPTVSVLVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYNQSQNHPALDVGPHRRLQWTWLGRAELQFADQTLHVSTVQMWLLLHFNQTEEVSVEALLKNSGLSPELLLQALLPLTSDSGPLTLQEGQDFPPRGVLRLREPGLQPRGEALWLLPPQTYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWHKGPNPPGSLGRAIAGGVACTSTDVLSCILHLLGQGYVERRDDWPQILTYATPEPTGPCRGQAEIPFFGSQTSETSKISPEAVAALASLQLPAGRTMSPREVEGLMEQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSDDPEPLLLAAGLRVPQAQAAPARPDHCPVCVSPLAPDRDLPALCCQHSCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCANLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFSCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLTKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQARDFAVNLRNRVSAIHEVPPPKSFTFLSDACRGLEQARKVLAYACVYSFYNQDTEHMDVVEQQIEALELHTNALQILLGEPPSPWHLPPKYRWVGDPAPAAHLHSGPWSFLCLVALLPSSSSTLQVHDTHPHPTFALITTCPHL", "length": 2452, "header": "tr|A0ABI0NWD1-1|A0ABI0NWD1_BOVIN Computationally mapped isoform of Cullin 9 OS=Bos taurus OX=9913 GN=CUL9 PE=3 SV=1 CANONICAL=E1BM39-1" }, "locus": { "chromosome": "23", "start_pos": 16820733, "end_pos": 16786304, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148963.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148963.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105292.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105292.1" } ] } }, { "isoform_ac": "E1BM39-1", "url": "https://www.uniprot.org/uniprotkb/E1BM39/entry#E1BM39-1", "sequence": { "sequence": "MVGERRTGDLTVPLGPRLQAYPEELLRQRPGQDGHPEYLIRWSVLKCGEVGRAGVEEGKAEHILMWLSAPEVYASCPTLLGERALSKGPQHETAGGPASFPRDPGSLDDVAMGEMEADVRALVRRAARQLAEGGTSSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEPQIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHCMAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNNSPEQGAGDRGSPTSREDLGREKSRGQRELEFSMAVGNLISELVRSMGWARNLSQQGTLPPRPTRSIFQPSISGPSLLLPTIVAPPRRQGRAFRQRAEFSSLSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWQSTSRTYWVHWHMLEILGPEETTEDTASAAAEEGAGAAVPGTALPSWDWKPVDGLYSLPYLQPEPQKNEKLGYLTQAEWWELLFFIRKLDICEQQSIYQSLRENLDESLGEKAVGEISVPVAMAESLLQVLRNRFEGSTLSDLLNSQIYTKYGLQPDALSGSSSSQNHSSTPDPEEESKSEATFSEEETESPNVKAQPLKAEAEPVKGKTELPMAQSDSQLFNQLLVTEGMALPAGMKEAAGEMIRALRGPGPRSSLDQYVAAVVATVQISSLDTSLQLSALCALSQAVEEVTERDHPLVHPDRFLREKLVKTLVELLTNQVGEKMVVVLALRLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAIASSSEISTSVTSQDSIHPLFDAQMTREIFASIDSATRPDSESLLLALPAAVILMLNTEGCSSAVRNGLLLLNLLLCNHHTLGDQIITRELRDTLFRHSGIAPGTEPMPTTRTILTMLLNRYSKPPGSPERSAAPETPSAQGQEGSPELLIRSLVGGPSAELLLDLERVLCREGGPGGAVRPLLKRLQQESQPFLLFLWTLDAPGPNKTLLLTALRVMTQLLDHTEAMVLPWHEVLEPCLNCLNGPGSDSEIVQELLCFLYRLASTHKDYAVVLCCLGAKDALTKVLEKHSAQLLLACELRDLVTECEKHAQLYSNLTSSILAGCIQMVLGQIEDHRRTYRPINIPFFDVFLRHLCQGSSVEVKEDKCWEKLEVSSNPHRASKLTDRNPKTYWESNGSTGSHFITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSASCINTELNTVNVMPSASRVVLLENLSRVWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIWAQAWSRDIAEDRKRLLQLCPRLNRVLRHEQNFADRFLPDEEAAQALGKTCWEALVSPLVQNITCPDAEGVSSLGWLLDQYLEQRESSRNPRGRAASFASRVRRLCHLLVHVEPPPGPSPEPSARPPSKSSKARDRSPGPSPVLPSSSLRNITQCWLSVVQEQVSTFLAAAWRAPDFVPRYCKLYERLQRAGLELFGPRAAFTLALRSGFSGALLQQSFLTTAHMSEQFARHIDQQIQSGLMGGTPGVEVLGRLQWHLEPIMVLSGLELATTFEHFYQHYMADRLLSLGSSWLEGAVLEQIGLCFPNRLPQQMLRSLSTSEELQRQFHVYQLQQLDKLFLEQEDEEEQGLEEEEEEEEAEKELFIEDPSPTVSVLVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYNQSQNHPALDVGPHRRLQWTWLGRAELQFADQTLHVSTVQMWLLLHFNQTEEVSVEALLKNSGLSPELLLQALLPLTSDSGPLTLQEGQDFPPRGVLRLREPGLQPRGEALWLLPPQTYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWHKGPNPPGSLGRAIAGGVACTSTDVLSCILHLLGQGYVERRDDWPQILTYATPEPTGPCRGQAEIPFFGSQTSETSKISPEAVAALASLQLPAGRTMSPREVEGLMEQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSDDPEPLLLAAGLRVPQAQAAPARPDHCPVCVSPLAPDRDLPALCCQHSCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCANLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFSCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLTKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQARDFAVNLRNRVSAIHEVPPPKSFTFLSDACRGLEQARKVLAYACVYSFYNQDTEHMDVVEQQIEALELHTNALQILLEETLLHCRDLASSLRLLRAEHLNTGLELLRRIQERLLAILQHSTQDFRVGLQSPSSESREAKGPNVPGSQPQGSSELEEEEEDEEPEWQQDEFEEELDNDSFSYDEESENLDRETFFFGDEDDDEEDDEGYD", "length": 2518, "header": "tr|E1BM39-1|E1BM39_BOVIN Isoform 1 of Cullin-9 OS=Bos taurus OX=9913 GN=CUL9 PE=3 SV=3 CANONICAL=E1BM39-1" }, "locus": { "chromosome": "23", "start_pos": 16821963, "end_pos": 16786304, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026522.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026522.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026522.5", "url": "https://www.ensembl.org/id/ENSBTAP00000026522.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1696, "start_aa": "Thr", "end_pos": 1696, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1696", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540077", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540077", "resource": "KEGG Pathway" }, { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K652-1", "protein_name": "Cullin-9", "gene_name": "Cul9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVGEQRAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWRVLKCSEEGKVSLEEEKTEYLLMWLSAPEVYANCPMLLRERSVSKGPQYEPTGEVGSFPRDPGGLDELAMAEMEDDVRALVRRAARQLAEGGASNLTVAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCSPEPQIRRSAGKMLQALAAHDAGSRAHVLLSLSQHEGIEQHMDFDSRYTLLELFAETTSTEEHCMALEGIHLPQLPGKLLFSLVKRYLCVTSLLDQLNNSPESGAGDQSSPCLPKEKSRGQRELEFSMAVGNLISELVRSMGWARNLSEQGALPPRPSRSIFQPCLSGPPLLLPTIVTTPRKPGRAFRGRSEFSSRSGYGEYVQQTVQPGMRVRILDDYEEISAGDEGEFQQSNNGVPPVQVFWQSTGRTYWVHWHMLEILGPEEATREPASAAVEKGAGATALGTACPSWDRKPAHGLYSLPYLQPESQKSEEPGYLTQGEWWELLFFIKKLDLCEQQPIFQNLHEKLDKAVGEKTLGEISVPIEMAEGVLQVLSNRFEGSNLCDLLNSHIYTKYGRLPKEPGRLPPSRGHSCTSEPEEGSESAASFSEKEESPKAEAEPAGAKPESPKAQSDSQLFNQLLVTEGMALAPETQAAATEMARTLRGPGPRSSLDQHVAAVLATVQISSLDTNLQLSGLGALSQAVEEVTERDHPLVRPDRSLREKLVKTLVDLLTNQVGEKMVVVLALRLLYLLMTKHEWRPLFAREGGIYAVLICMQEYKTSVLVQQAGLAALKMLAIANSSEVPTFVTGRDSIQPLFDTQMTREIFASIDSATRPGSESLLLSVPAAVVLMLNTEGCSSAVRNGLLLLNLLLCNHHTLGDQIITQELRDTLFRHSGIAPGTEPMPTTRTILMMLLSRYSEPWGSPERAALETPSTQGQDGSPESLIRSLVGDLSAELFLDLERVLCHEGSPQGAMTPLLKRLQQETQPFLLLLRTLDAPGPNRALLLTVLRVMTRLLDYPETMVLPWHEVLEPCLNCLNGPSSDSEVVQELTCFLHRLALMHKDYAVVLCCLGAKEALSKVLDKHSTQLLLASELRHLVTECEKYAQLYTNLTSSLLAACIQMVLGQIEDHRRTYKPINIPFFDVFLRHLCQGSSVEVKEDRCWEKVEVSSNPHRASKLTDRNPKTYWESNGSTGSHSITLHMHRGVLIRQLTLLVASEDSSYMPARVVVFGGDSVGCISTELNTVNVVPSASRVTLLENLSRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDRQRLLQLYPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAGGVSSLGWLLDQYLEHREKARSRQGQAASFASQVRRLCHLLVHVEAPPGPSPEPSSQPLSKSSKSQDGSPAPAPVRPSTTLRNITQCWLAVVQGQASRFLASAWRASDFVPRYCDLYERLQRAGSELFGPRAAFTLALRSGFSGALLQQSFLTAAHISEQFARHIDQQIQGGLLGGAAGVEMLGRLQRHLEPIMVLSGLELATTFEHFYQYYMADRLLSLGSSWLEGAVLEQIGLCFPNRLPQLMLQSLRTSEELQRGFLLFQLQQLDRQLLEQGEQEEWKLERLEEEDRGQETGRELLTEDPGPAISVLVLSPRCWPVSPLCYLHQPRKHLPTEFCDALDGFSSFYSHSEELGTGSWRLRCIPGGRRGKAEATRQECQHYPVLDMGPHRRLQWTWLGRAELQFGDQTLHVSTVQMWLLLNFNQTEEVSVEILLRNSGLSPELLHQALLPLTSDSGPLTLEEAQDFPQGGVLRLREPRSQTHEEVLWLIPPQTYLSVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGRLGRSAAVGVACSSTDVLSCILHLLGQGYVERRDDRPQVLMYATPEPMGHCRGQADVPFCGNQSTETSKPSPEAVVALASLQLPAGRTMSPQEVEGLMEQTVRQVQETLNLEPDVAQHLLAYSHWGTEQLLQSYSEDPEPLLLAAGLRVPQPQEVPARPDQCPVCISPLGPNDDSPSLCCLHCCCKSCWNEYLTTRIEQNFVLNCTCPIADCPAQPTGAFIRNIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGSGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCARCNHGFCWRCLRSWKPSHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNQASAIHEVPPPKSFTFLQDACRALEQARKVLAYACVYSFYSQGTEYMDVVEQQTENLELHTNALQILLEETLLRCQDLASSLRLLRADCLSTGTELLRRIQERLLAILQHSTQDFRVGLQSPSVETREVKGSNVPSDQPQGSSGLEVEDEEEEEEEEEEEDVPEWQHEFDEELDNDSFSYDEESENLDRETFFFGDEDDDDESYD", "length": 2541 }, "evidence": [ { "id": "E1BM39", "url": "https://omabrowser.org/oma/group/E1BM39/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IWT3-1", "protein_name": "Cullin-9", "gene_name": "CUL9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKAEHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEPQIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHCMAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQRELEFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQGWVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFWQSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPYLQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVSVEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKSEASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEAASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLVRPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD", "length": 2517 }, "evidence": [ { "id": "E1BM39", "url": "https://omabrowser.org/oma/group/E1BM39/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" }, { "name": "ubiquitin ligase complex scaffold activity", "id": "GO:0160072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160072", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" }, { "name": "cullin-RING ubiquitin ligase complex", "id": "GO:0031461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031461", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" }, { "name": "Cul7-RING ubiquitin ligase complex", "id": "GO:0031467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031467", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "E1BM39", "url": "https://www.uniprot.org/uniprotkb/E1BM39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1013, "end_pos": 1015, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1122, "end_pos": 1124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1202, "end_pos": 1204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1271, "end_pos": 1273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1387, "end_pos": 1389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1476, "end_pos": 1478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1738, "end_pos": 1740, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1785, "end_pos": 1787, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2115, "end_pos": 2117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2159, "end_pos": 2161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2281, "end_pos": 2283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2485, "end_pos": 2487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM39" }, { "id": "PS50069", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50069" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cullin family profile", "eco_id": "ECO_0000259", "start_pos": 1549, "end_pos": 1814, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM39" }, { "id": "PS51284", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51284" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOC", "eco_id": "ECO_0000259", "start_pos": 1148, "end_pos": 1327, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM39" }, { "id": "PS51873", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51873" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 2069, "end_pos": 2286, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1696 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1013, "end_pos": 1015 }, { "start_pos": 1122, "end_pos": 1124 }, { "start_pos": 1202, "end_pos": 1204 }, { "start_pos": 1271, "end_pos": 1273 }, { "start_pos": 1387, "end_pos": 1389 }, { "start_pos": 1476, "end_pos": 1478 }, { "start_pos": 1738, "end_pos": 1740 }, { "start_pos": 1785, "end_pos": 1787 }, { "start_pos": 2115, "end_pos": 2117 }, { "start_pos": 2159, "end_pos": 2161 }, { "start_pos": 2281, "end_pos": 2283 }, { "start_pos": 2485, "end_pos": 2487 }, { "start_pos": 274, "end_pos": 276 }, { 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mapped isoform of Germ cell-specific gene 1-like protein OS=Bos taurus OX=9913 GN=GSG1L PE=3 SV=1 CANONICAL=E1BM65-1" }, "locus": { "chromosome": "25", "start_pos": 25591667, "end_pos": 25339639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101633.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101633.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101403.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101403.1" } ] } }, { "isoform_ac": "E1BM65-1", "url": "https://www.uniprot.org/uniprotkb/E1BM65/entry#E1BM65-1", "sequence": { "sequence": "MKTSRRGRALLAVALNLLALLFATTAFLTTHWCQGTQRVPKPGCGQGGSANCPNSGANATANGTAAPAVPAAPAAGNGPPGGALYSWETGDDRFLFRNFHTGIWYSCEEELGGLGEKCRSFIDLAPASEKGVLWLSVVSEVLYILLLVVGFSLMCLELFHSSNVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKVFEQGYREEPTFIDPEAVKYFRERMEKGDGHEEEDFRLDCRHERYPARHQPHMGDSWPRSSAHEAAELNRQCWVLGHWV", "length": 330, "header": "tr|E1BM65-1|E1BM65_BOVIN Isoform 1 of Germ cell-specific gene 1-like protein OS=Bos taurus OX=9913 GN=GSG1L PE=3 SV=2 CANONICAL=E1BM65-1" }, "locus": { "chromosome": "25", "start_pos": 25591667, "end_pos": 25339639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034207.6", "url": "https://www.ensembl.org/id/ENSBTAT00000034207.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034107.4", "url": "https://www.ensembl.org/id/ENSBTAP00000034107.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511049", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511049", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z7H4-1", "protein_name": "Germ cell-specific gene 1-like protein", "gene_name": "Gsg1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"MKTTRKCRALLSVGLNLLALLFSTTAFITTYWCEGTQRVPKPNCSKDRRHNCIDYGVNETDPSKVHYSWETGDDRFLFRHFHTGIWYSCEENIHGGGEKCRSFIDLAPASERGVLWLSVVSEVLYIMLLVVGFSLMCLELFHSSNVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQITVSLGPEDWRPHTWDYGWSFCMAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKLFEQGLREEQTFLDPETFHYFRDRSVQSISSSVDVYPSHGSSHGNSRGKMRSPPAPVDQGDNTESLGEEQC", "length": 304 }, "evidence": [ { "id": "E1BM65", "url": "https://omabrowser.org/oma/group/E1BM65/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6UXU4-1", "protein_name": "Germ cell-specific gene 1-like protein", "gene_name": "GSG1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKTSRRGRALLAVALNLLALLFATTAFLTTHWCQGTQRVPKPGCGQGGRANCPNSGANATANGTAAPAAAAAAATASGNGPPGGALYSWETGDDRFLFRNFHTGIWYSCEEELSGLGEKCRSFIDLAPASEKGVLWLSVVSEVLYILLLVVGFSLMCLELFHSSNVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKVFEQGYREEPTFIDPEAIKYFRERMEKRDGSEEDFHLDCRHERYPARHQPHMADSWPRSSAQEAPELNRQCWVLGHWV", "length": 331 }, "evidence": [ { "id": "E1BM65", "url": "https://omabrowser.org/oma/group/E1BM65/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BM65", "url": "https://www.uniprot.org/uniprotkb/E1BM65" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BM65", 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"UniProtKB", "id": "E1BM65", "url": "https://www.uniprot.org/uniprotkb/E1BM65" } ], "pmid": "" }, { "name": "regulation of cell communication", "id": "GO:0010646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010646", "evidence": [ { "database": "UniProtKB", "id": "E1BM65", "url": "https://www.uniprot.org/uniprotkb/E1BM65" } ], "pmid": "" }, { "name": "regulation of postsynaptic neurotransmitter receptor internalization", "id": "GO:0099149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099149", "evidence": [ { "database": "UniProtKB", "id": "E1BM65", "url": "https://www.uniprot.org/uniprotkb/E1BM65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM65-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 330, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM65-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM65" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 58, "end_pos": 60 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NIS7-1", "uniprot_ac": "A0ABI0NIS7", "uniprot_id": "A0ABI0NIS7_BOVIN", "mass": { "chemical_mass": 41159.0, "monoisotopic_mass": 41159.0 }, "refseq": {}, "gene_names": [ { "name": "DENND10", "type": "recommended", "evidence": [ { "id": "A0ABI0NIS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIS7" } ] } ], "protein_names": [ { "name": "DENN domain containing 10", "type": "synonym", "evidence": [ { "id": "A0ABI0NIS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIS7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIS7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIS7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DENND10", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIS7", "locus": { "chromosome": "26", "start_pos": 39309566, "end_pos": 39292002, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008729", "url": "https://www.ensembl.org/id/ENSBTAG00000008729" } ] } } ], "crossref": [ { "id": "ENSBTAG00000008729", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008729", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "534370", "url": "https://www.ncbi.nlm.nih.gov/gene/534370", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534370", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534370", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKDIAMF", "url": "https://omabrowser.org/oma/group/HKDIAMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BF38", "url": "https://www.orthodb.org/?gene=E1BF38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28544", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28544", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28544:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28544:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08616", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08616", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NIS7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NIS7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF38", "url": "https://www.uniprot.org/uniprotkb/E1BF38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF38-1", "url": "https://www.uniprot.org/uniprotkb/E1BF38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTSRSRWRPRVSFVQEGTLEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITTVEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLDADELEALQMCPGYIAGFVDLDVSNRSDLYDVFVNLADSEITIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDISLKTKEIFTNLAPFSEVSDDGEKRVLNYEALKQRRFPPATENFLYHLAAAEQMLKI", "length": 359, "header": "tr|A0ABI0NIS7-1|A0ABI0NIS7_BOVIN Isoform 1 of DENN domain containing 10 OS=Bos taurus OX=9913 GN=DENND10 PE=3 SV=1 CANONICAL=A0ABI0NIS7-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NIS7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIS7/entry#A0ABI0NIS7-1", "sequence": { "sequence": "MPTSRSRWRPRVSFVQEGTLEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITTVEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLDADELEALQMCPGYIAGFVDLDVSNRSDLYDVFVNLADSEITIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDISLKTKEIFTNLAPFSEVSDDGEKRVLNYEALKQRRFPPATENFLYHLAAAEQMLKI", "length": 359, "header": "tr|A0ABI0NIS7-1|A0ABI0NIS7_BOVIN Isoform 1 of DENN domain containing 10 OS=Bos taurus OX=9913 GN=DENND10 PE=3 SV=1 CANONICAL=A0ABI0NIS7-1" }, "locus": { "chromosome": "26", "start_pos": 39308196, "end_pos": 39292675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144621.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144621.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104141.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104141.1" } ] } }, { "isoform_ac": "E1BF38-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIS7/entry#E1BF38-1", "sequence": { "sequence": "MAATEAADTQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITTVEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLDADELEALQMCPGYIAGFVDLDVSNRSDLYDVFVNLADSEITIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDISLKTKEIFTNLAPFSEVSDDGEKRVLNYEALKQRRFPPATENFLYHLAAAEQMLKI", "length": 357, "header": "tr|E1BF38-1|A0ABI0NIS7_BOVIN Computationally mapped isoform of DENN domain containing 10 OS=Bos taurus OX=9913 GN=DENND10 PE=3 SV=2 CANONICAL=A0ABI0NIS7-1" }, "locus": { "chromosome": "26", "start_pos": 39308196, "end_pos": 39292041, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011498.8", "url": "https://www.ensembl.org/id/ENSBTAT00000011498.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011498.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011498.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534370", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534370", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZJN7-1", "protein_name": "DENN domain containing 10", "gene_name": "DENND10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAEATDPQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENRLLHPFVYGQYRRTWFYITTVEVPDASVLKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLDADELEALQMCPGYVAGFVDLEVSNRSDLYDVFVNLADSEITIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDISLKTKEIFTNLAPFSEVSDDGEKRVLNYEALKQRRFPPATENFLYHLAAAEQMLKI", "length": 357 }, "evidence": [ { "id": "A0ABI0NIS7", "url": "https://omabrowser.org/oma/group/A0ABI0NIS7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0X4Q7-1", "protein_name": "Family with sequence similarity 45 member A", "gene_name": "FAM45A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEPETQLLLGVGLIEKDTNGDALWVWCYPSVTAELRTLLLRKCCLTDESKLLHTFVFGQYKRTWFYITTVEVQDSPALKKVTHFSIVLTAKDFNPEKYGAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILYTALMLKKRIVVYHPRIEAIQEFTRTLPALVWHRQDWSILHSYVHLNEEEVEALKACAGYVAGFTDSEVNSRPDLYDVYVNLADSEITISPVVKEAMTMGKLHKEIGQLIVQSAEDPDKSDSQVIKDISLKTKEILSTLASLTEVSDGNEKPTLNSEALKQKQFPPATENFLFHLAAAEQMLKI", "length": 354 }, "evidence": [ { "id": "A0ABI0NIS7", "url": "https://omabrowser.org/oma/group/A0ABI0NIS7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LUV8-1", "protein_name": "DENN domain containing 10", "gene_name": "Dennd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVAKSWGGTCSAEPGKRRKMAAVVAMDTQLMLGVGLIEKDTNGEVLWVWCYPSTTASLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYVTTVEVPDSSVLKKVTHFSIVLTAKDFNPEKYAAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEENGSFLSRDFDGRKAYLAGSIKDIVSQFGMETIILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWSILHSYMHLHAEELEGLQMCTGYIAGFVDLEVSNRPDLYDVFVNLADSEIIIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDIALKTKEIFTHLAPFSEASDAGKVFLNVEALKQKRFPPATENFLYHLAAAEQMLKADSYFIHGSLSSPLGAALLSVRLRAPGTVGTEASLLHKCCWEP", "length": 418 }, "evidence": [ { "id": "A0ABI0NIS7", "url": "https://omabrowser.org/oma/group/A0ABI0NIS7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A8E7G4-1", "protein_name": "DENN domain-containing protein 10", "gene_name": "dennd10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATPELMLSLGLIEKDVNADTLWVWCYPSIDADLREVMLRKCCLTLDNQVLHTFVFGQFCRTWYYITTVEVQEPTVLKKVTHFSIVVTAKDFNPEKYAAFSRVLCRTYMKHGSPVKMMEGYIAVLTKGICQSDENGSFLIKDYDVRKALLAGSLKDVVSQFGMETIILYTALMLKKRVVVYHPRIEALLEFTRALPCLVWHRKDWSILHPFVHLENDELENLKVCTGYVAGFVDPEVKDRSDLFDVFVNLPDSEITVSQNAKEAMSMGKLHKEIGNFIVQAAEDADRSDAQVIKDISVKTKEILSNLMSLADHADNSKLTLECLKQGHYPPATENFLFHLAAAEQLLKI", "length": 349 }, "evidence": [ { "id": "A0ABI0NIS7", "url": "https://omabrowser.org/oma/group/A0ABI0NIS7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q55FE3-1", "protein_name": "DENN domain-containing protein 10", "gene_name": "dennd10", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATSISLEDSITIFEKDQNSDVLMSWCFPTITEDLKSVILNRTSLLQEKISLQFSFSKFKNSWIYIYTTSVETQQINKEDGSITQINVPDSLKRVVAFSLVLVRNQFNPEKYGSLAQIMSSVYKQTGDCSKLLECQLRVFNRGQFDVGSMGKFVDSSFDVRRSYLQTSIKDIIQLFGEEIILIWSAMAMKKRIVVYSEKLSSLLKVIRALPLFVFHRQNWNILRPFVTISDLELKDLVSTGVYCAGFTDSSIKSREDLYDILVDLSSKEVSVSSQSKDQFILGSFHKDVLRFLLDSLDDEEITDQNVIKGLNLKMKELLTKLESLKETNEETGKSSITLESLETRKLPNGMSTFLFNIANAEGLNG", "length": 366 }, "evidence": [ { "id": "A0ABI0NIS7", "url": "https://omabrowser.org/oma/group/A0ABI0NIS7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8TCE6-1", "protein_name": "DENN domain-containing protein 10", "gene_name": "DENND10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAEVADTQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITTIEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLNADELEALQMCTGYVAGFVDLEVSNRPDLYDVFVNLAESEITIAPLAKEAMAMGKLHKEMGQLIVQSAEDPEKSESHVIQDIALKTREIFTNLAPFSEVSADGEKRVLNLEALKQKRFPPATENFLYHLAAAEQMLKI", "length": 357 }, "evidence": [ { "id": "A0ABI0NIS7", "url": "https://omabrowser.org/oma/group/A0ABI0NIS7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D8N2-1", "protein_name": "DENN domain-containing protein 10", "gene_name": "Dennd10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVVAMDTQLMLGVGLIEKDSNGEALWVWCYPSTTASLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYVTTVEVPDSSVLKKVTHFSIVLTAKDFNPEKYAAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEENGSFLSRDFDGRKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYMHLHAEELEGLQMCTGYIAGFVELEVSNRPDLYDVFVNLADSEITIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDIALKTKEIFTHLAPFSEVSDDGGKVILNVEALKQQRFPPATENFLYHLAAAEQMLKV", "length": 357 }, "evidence": [ { "id": "A0ABI0NIS7", "url": "https://omabrowser.org/oma/group/A0ABI0NIS7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of early endosome to late endosome transport", "id": "GO:2000641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000641", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIS7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIS7" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": 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Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'.", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1#function" }, { "database": "UniProtKB", "id": "ARBA00058012", "url": "https://www.uniprot.org/uniprotkb/ARBA00058012#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SHPRH", "url": "https://www.uniprot.org/uniprotkb/E1BLB1", "locus": { "chromosome": "9", "start_pos": 83144823, "end_pos": 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048686", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048686", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BLB1", "url": "https://www.orthodb.org/?gene=E1BLB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45865", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45865", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45865:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45865:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00538", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00538", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21325", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21325", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8866654", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866654", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLB1-1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSRRKRAPPVRVDEETQQQLCWNMHEDRRNEPLTLTDDEQSYPGLDPSPAHRIILDDSLKEEVAHREKKRCSKAVSISKSIDKEETGGIFSPLSVKLNIVISPYNFDNSWKAFLGEFTLQLLPEQCLIENFSEKSFTLMSPKLSNQFLIYVHSGCENIEKKERGLNEPVSICDKGIQVESSFSSEMLEDLEWLQKKKRIKLYQKPEENNIIKVGIYLLEAGLAKPDFLSDASSRMKKFNQLMKRVMEKLYNFIIPDVLEEDEEGSDSEPEGQDIDELYHFVKQTHQQETRSIQVDVQHPALTPVLRPYQREAVNWMLQQEHFKSTPASENALHFLWREIVTSEGLKLYYNPYTGCIIREYPNAGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGEVVNYFIPSHYSGGNVKKTETQNMEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDIYDKTRKQAVGSPRKTQKESRKSGNKDTDSEYLPSNTSDDDDDPYYYYCKPRRNRSKWRKKPVPSTKREKSQLNISLNPQDHCPPTGNSEITDVTTSESTCVFEVNQEHSAKDQAESLNPVGDDMPHSNIMGSYNSSSYRFGCICGELDQVDCKPRVQCLKCHLWQHAKCVNYEEKNLKIKPFYCPHCLVAMEPVSTRATLIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPAVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGVEPYCVRHWWVRLLYRPYCKKNPHFLYSFIAKIMWRSAKKDVIDQIQIPPQTEETHWLHFSPVERHFYHRQHEVCCQDAVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKEKLKTDSLQRLHATHNLMELLTAKHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALLPVQQTIRDLQRKIHSNSPWWLNVIQRAIEFGIEEELAQRVRNEITSNYKQQTGKLSMSEKFHDCRGLQFLLTTHMEELSKFQKQVREAVKNLEGPPSRHVIESATICHLRPVRLPLNCCVFCKADELFTEYESKLFSHTVKGQTAIFEEMIEDEEGLVDDRITTTNRGLWAISETERSMKALLSFAKSHRFDVEFIDEGSNSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGINPEPCPICARQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIRCAICRQTTSHKEISYVFTSEKASQEEDIPVKGSHSTKVEAVVRTLMRIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQENLSAFKYDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERRWHSDEEYTCQCRKHGFDPWARKIPWRRKWQPTPVFLPGESHGQRSLVGYSPQWSQKSWIPLSNCTRAHTQKNTYFYSKEYLYLRELREVLCTFLSIRSVLKRS", "length": 1757, "header": "tr|E1BLB1-1|E1BLB1_BOVIN Isoform 1 of E3 ubiquitin-protein ligase SHPRH OS=Bos taurus OX=9913 GN=SHPRH PE=3 SV=3 CANONICAL=E1BLB1-1" }, "isoforms": [ { "isoform_ac": "E1BLB1-1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1/entry#E1BLB1-1", "sequence": { "sequence": "MSSRRKRAPPVRVDEETQQQLCWNMHEDRRNEPLTLTDDEQSYPGLDPSPAHRIILDDSLKEEVAHREKKRCSKAVSISKSIDKEETGGIFSPLSVKLNIVISPYNFDNSWKAFLGEFTLQLLPEQCLIENFSEKSFTLMSPKLSNQFLIYVHSGCENIEKKERGLNEPVSICDKGIQVESSFSSEMLEDLEWLQKKKRIKLYQKPEENNIIKVGIYLLEAGLAKPDFLSDASSRMKKFNQLMKRVMEKLYNFIIPDVLEEDEEGSDSEPEGQDIDELYHFVKQTHQQETRSIQVDVQHPALTPVLRPYQREAVNWMLQQEHFKSTPASENALHFLWREIVTSEGLKLYYNPYTGCIIREYPNAGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGEVVNYFIPSHYSGGNVKKTETQNMEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDIYDKTRKQAVGSPRKTQKESRKSGNKDTDSEYLPSNTSDDDDDPYYYYCKPRRNRSKWRKKPVPSTKREKSQLNISLNPQDHCPPTGNSEITDVTTSESTCVFEVNQEHSAKDQAESLNPVGDDMPHSNIMGSYNSSSYRFGCICGELDQVDCKPRVQCLKCHLWQHAKCVNYEEKNLKIKPFYCPHCLVAMEPVSTRATLIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPAVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGVEPYCVRHWWVRLLYRPYCKKNPHFLYSFIAKIMWRSAKKDVIDQIQIPPQTEETHWLHFSPVERHFYHRQHEVCCQDAVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKEKLKTDSLQRLHATHNLMELLTAKHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALLPVQQTIRDLQRKIHSNSPWWLNVIQRAIEFGIEEELAQRVRNEITSNYKQQTGKLSMSEKFHDCRGLQFLLTTHMEELSKFQKQVREAVKNLEGPPSRHVIESATICHLRPVRLPLNCCVFCKADELFTEYESKLFSHTVKGQTAIFEEMIEDEEGLVDDRITTTNRGLWAISETERSMKALLSFAKSHRFDVEFIDEGSNSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGINPEPCPICARQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIRCAICRQTTSHKEISYVFTSEKASQEEDIPVKGSHSTKVEAVVRTLMRIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQENLSAFKYDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERRWHSDEEYTCQCRKHGFDPWARKIPWRRKWQPTPVFLPGESHGQRSLVGYSPQWSQKSWIPLSNCTRAHTQKNTYFYSKEYLYLRELREVLCTFLSIRSVLKRS", "length": 1757, "header": "tr|E1BLB1-1|E1BLB1_BOVIN Isoform 1 of E3 ubiquitin-protein ligase SHPRH OS=Bos taurus OX=9913 GN=SHPRH PE=3 SV=3 CANONICAL=E1BLB1-1" }, "locus": { "chromosome": "9", "start_pos": 83227904, "end_pos": 83145827, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010673.5", "url": "https://www.ensembl.org/id/ENSBTAT00000010673.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010673.5", "url": "https://www.ensembl.org/id/ENSBTAP00000010673.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-8866654", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866654", "resource": "Reactome", "description": "E3 ubiquitin ligases ubiquitinate target proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "E1BLB1", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1569, "end_pos": 1571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1717, "end_pos": 1719, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 574, "end_pos": 576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" }, { "start_pos": 655, "end_pos": 657, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-8943003", "name": "SHPRH polyubiquitinates monoubiquitinated PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P5K3-1", "Q32P99-1", "F6RDI0-1", "E1BLB1-1" ], "evidence": [ { "id": "R-BTA-8943003", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8943003" } ] }, { "id": "R-BTA-8943007", "name": "SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P5K3-1", "Q32P99-1", "F6RDI0-1", "E1BLB1-1" ], "evidence": [ { "id": "R-BTA-8943007", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8943007" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BLB1", "gene_name": "SHPRH", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BLB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BLB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ] } ] }, { "uniprot_ac": "F6RDI0", "gene_name": "RAD18", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F6RDI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F6RDI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ] } ] }, { "uniprot_ac": "Q0P5K3", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] }, { "ec_number": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BLD9", "url": "https://www.uniprot.org/uniprotkb/E1BLD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLD9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAVAAEAPLRLPAAPPLAFCCYTSVLLLFAFSLPGSRASNQPPGGGGGGDCPGGKGKSINCSELNVRESDLRVCDESSCKYGGVCKEDGDGLKCACQFQCHTNYIPVCGSNGDTYQNECFLRRAACKHQKEITVVARGPCYSDNGSGSGEGAEEEGSGAEVHRKHSKCGPCKYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTDTDDTSLLGKKDDGLQYRPDVKDASDQREDVYIGNHMPCPENLNGYCIHGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILYVVPSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFTSDTSSRMV", "length": 379, "header": "tr|E1BLD9-1|E1BLD9_BOVIN Isoform 1 of Tomoregulin-1 OS=Bos taurus OX=9913 GN=TMEFF1 PE=3 SV=4 CANONICAL=E1BLD9-1" }, "isoforms": [ { "isoform_ac": "E1BLD9-1", "url": 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"https://www.uniprot.org/uniprotkb/E1BLF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLF6-1", "url": "https://www.uniprot.org/uniprotkb/E1BLF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRSSKMEFFQKLGYSREDVARVLGKLGEDALVNDVLQELIQTGSRPAAPEGSAAPLLVPRGSCGTPDSAQGGLGADPGEDSGGPASSLRPIVIDGSNVAMSHGNKEIFSCRGIQLAVDWFRDRGHTYIKVFVPSWRKEPPRSDAPITEQHVLEELERQAVLVYTPSRKVSGKRVVCYDDRYIVKVAYDLDGVIVSNDNYRDLQSENPEWKWFIEQRLLMFSFVNDRFMPPDDPLGRRGPTLSNFLSRKPKPPEPSWQHCPYGKKCTYGIKCKFYHPERPHQAQLAVADELRAQTRAWRGAGGEEERRGSARAASLAEQGGSRDAPAARPGPRELGTRSLPTARRSAGLATLESSFSRLFLSDDPGLLRAPHRGPGCGLAPGQPGPDWVAPGSLSSLPARPGLLSPPGLRGEYGPRAPQSDRRSPRQQPSDPWVLPPGAGQLPGRSAWAESDWDDGAFGGPLRPAPQAVAGEVDARSRARTALCSIFPPHEVDSIMALFPELSDVARLMLLIQRFQRSSAPVGKR", "length": 525, "header": "tr|E1BLF6-1|E1BLF6_BOVIN Isoform 1 of Zinc finger CCCH-type containing 12D OS=Bos taurus OX=9913 GN=ZC3H12D PE=3 SV=3 CANONICAL=E1BLF6-1" }, "isoforms": [ { "isoform_ac": "E1BLF6-1", "url": "https://www.uniprot.org/uniprotkb/E1BLF6/entry#E1BLF6-1", "sequence": { "sequence": "MQRSSKMEFFQKLGYSREDVARVLGKLGEDALVNDVLQELIQTGSRPAAPEGSAAPLLVPRGSCGTPDSAQGGLGADPGEDSGGPASSLRPIVIDGSNVAMSHGNKEIFSCRGIQLAVDWFRDRGHTYIKVFVPSWRKEPPRSDAPITEQHVLEELERQAVLVYTPSRKVSGKRVVCYDDRYIVKVAYDLDGVIVSNDNYRDLQSENPEWKWFIEQRLLMFSFVNDRFMPPDDPLGRRGPTLSNFLSRKPKPPEPSWQHCPYGKKCTYGIKCKFYHPERPHQAQLAVADELRAQTRAWRGAGGEEERRGSARAASLAEQGGSRDAPAARPGPRELGTRSLPTARRSAGLATLESSFSRLFLSDDPGLLRAPHRGPGCGLAPGQPGPDWVAPGSLSSLPARPGLLSPPGLRGEYGPRAPQSDRRSPRQQPSDPWVLPPGAGQLPGRSAWAESDWDDGAFGGPLRPAPQAVAGEVDARSRARTALCSIFPPHEVDSIMALFPELSDVARLMLLIQRFQRSSAPVGKR", "length": 525, "header": "tr|E1BLF6-1|E1BLF6_BOVIN Isoform 1 of Zinc finger CCCH-type containing 12D OS=Bos taurus OX=9913 GN=ZC3H12D PE=3 SV=3 CANONICAL=E1BLF6-1" }, "locus": { "chromosome": "9", "start_pos": 86715401, "end_pos": 86694185, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009713.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009713.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009713.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009713.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:615863", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615863", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A0I4-1", "protein_name": "Zinc finger CCCH type containing 12D", "gene_name": "Zc3h12d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERRGKMEFFQKLGYSQEDVVRVLGKLGDGALVNDVLQELIQTGSRPKAQEDPANGTGIVLMPRGCCGVRDSAQQGLGLGLEEAGGDPASFLRPIVIDGSNVAMSHGNKEAFSCRGIRLAVDWFRDRGHTYIKVFVPSWRKEPSRSDTPIREQHVLEELERQAVLVYTPSRKVNGKRVVCYDDRYIVKLAYEKDGVIVSNDNYRDLQNENPEWKWFIEQRLLMFSFVNDRFMPPDDPLGRRGPTLSNFLSKKPRPPEPSWQHCPYGKKCTYGVKCRFYHPERPHQGQLPVADELRAKTRAWPGGGAGESRPPSARSRPGAARPLPLEPGAHNPTPAPQPAALTALNQSFARLTFSDTAASGVVSLSRGPDRMPTSGPTSWASPSLRAGSVATQGSPGLRCLRTPNSLLSPGDLGSPICPQSQPSDRHCSRGMHSDLPPQRRPPEDPWAFLPSSYGYLNHSVWAESAWSENTFGRPSGSAQSTINSGGTRASLCSAFPSDREDPVMASDPVLSDVALRTLLQRSQKTGAPLGDP", "length": 533 }, "evidence": [ { "id": "E1BLF6", "url": "https://omabrowser.org/oma/group/E1BLF6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S7S2-1", "protein_name": "Zinc finger CCCH-type containing 12D", "gene_name": "ZC3H12D", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERSRKMEFFQKLGYGREDVLRVLDKLGEDALVNDVLQELIQTGSRPSAHQSSAAPAPLLVPRGCCGTPDSAQRGLAVDLEQESGCPASSLRPIVIDGSNVAMSHGNKEAFSCRGIQLAVDWFRDRGHTYIKVFVPSWRKDPPRSDTPIREQHVLEELERQAVLVYTPSRKVSGKRVVCYDDRYIVKVAYDQDGVIVSNDNYRDLQSENPEWKWFIEQRLLMFSFVNDRFMPPDDPLGRRGPTLNNFLSRKPKPPEPSWQHCPYGKKCTYGIKCKFYHPERPHHAQLAVADELRAQTRVWRSAGGEQGVSWGGPIARSGPREPGARSLPPARPLPDVATLEGSFSRLALSDDSGLLRATPPPRPSCPDWRVPGLPSSQPAPPGPRGGSRQGASKSDRCPPRPADPWALPPGAGRLLDRSSWAESGWDDTAFGGHLGSAAQVRAGEVDARAQARTVLCSIFPSHQVDSVMALFPALSDVTRLIFLIQRFQRSGEPMGKPLGASRGHRM", "length": 507 }, "evidence": [ { "id": "E1BLF6", "url": "https://omabrowser.org/oma/group/E1BLF6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BIY3-1", "protein_name": "Probable ribonuclease ZC3H12D", "gene_name": "Zc3h12d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEHRSKMEFFQKLGYSQEDVVRVLGKLGDSALVNDVLQELIQTGSRPRAQEDPASGTGVVLIPRGCCGVQDSAQQGPGTRPRRGWRRSSPLLRPIVIDGSNVAMSHGNKEAFSCRGIRLAVDWFTDRGHTYIKVFVPSWRKEPSRSDTPIREQHVLEELERQAVLVYTPSRKVNGKRVVCYDDRYIVKVAYEKDGIIVSNDNYRDLQNENPEWKWFIEQRLLMFSFVNDRFMPPDDPLGRRGPTLSNFLSKKPRPPEPSWQHCPYGKKCTYGVKCRFYHPERPHHGQLSVADELRAKTRAWLGGGAEEPRTPSARSRPTTARLLPQEPGEHDLPPAPQPAVLAALNRSFARLTFSDTAASGVVSQSRGPDWMPTGVPTSWAPPSLRAGSAATIGLPGMRSLRTPNNPLSPGDLGSPICPQARLSERHRSRDMHSDLPPQRRPLEDPWALLPSSYCYLNHSVWSESAWGEDIFRGPSESAQPVANGGGTRPVHCSFFPPDQDHPVMASGPPLSDMALLTLLQRSQKTGAPLGDP", "length": 533 }, "evidence": [ { "id": "E1BLF6", "url": "https://omabrowser.org/oma/group/E1BLF6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1BLF6", "url": "https://www.uniprot.org/uniprotkb/E1BLF6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BLF6", "url": "https://www.uniprot.org/uniprotkb/E1BLF6" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1BLF6", "url": "https://www.uniprot.org/uniprotkb/E1BLF6" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "E1BLF6", "url": "https://www.uniprot.org/uniprotkb/E1BLF6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BLF6", "url": "https://www.uniprot.org/uniprotkb/E1BLF6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BLF6", "url": "https://www.uniprot.org/uniprotkb/E1BLF6" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "E1BLF6", "url": "https://www.uniprot.org/uniprotkb/E1BLF6" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "E1BLF6", "url": "https://www.uniprot.org/uniprotkb/E1BLF6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "E1BLF6", "url": "https://www.uniprot.org/uniprotkb/E1BLF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLF6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 525, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLF6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLF6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLF6" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 279, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLG9-1", "uniprot_ac": "E1BLG9", "uniprot_id": "E1BLG9_BOVIN", "mass": { "chemical_mass": 81173.0, "monoisotopic_mass": 81173.0 }, "refseq": { "ac": "NP_001179073", "name": "coiled-coil domain-containing protein 13", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179073" }, "gene_names": [ { "name": "CCDC13", "type": "recommended", "evidence": [ { "id": "E1BLG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLG9" } ] }, { "name": "CCDC13", "type": "synonym", "evidence": [ { "id": "NP_001179073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179073" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 13", "type": "synonym", "evidence": [ { "id": "E1BLG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLG9/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 13", "type": "synonym", "evidence": [ { "id": "NP_001179073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179073" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLG9", "url": "https://www.uniprot.org/uniprotkb/E1BLG9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC13", "url": "https://www.uniprot.org/uniprotkb/E1BLG9", "locus": { "chromosome": "22", "start_pos": 14839301, "end_pos": 14871242, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013015", "url": "https://www.ensembl.org/id/ENSBTAG00000013015" } ] } } ], "crossref": [ { "id": "E1BLG9", "url": "https://alphafold.ebi.ac.uk/entry/E1BLG9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013015", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013015", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538960", "url": "https://www.ncbi.nlm.nih.gov/gene/538960", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538960", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538960", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BLG9", "url": "https://www.orthodb.org/?gene=E1BLG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31935:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31935:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001179073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BLG9", "url": "https://www.uniprot.org/uniprotkb/E1BLG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLG9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEDEGSQDTLRLQFRAMQEMQHKRLQKQMEKRKEKELSLQSRGDDQKEPLEISDGLSVLQAGEQNSKTSFQQRVLEDEIEQLRDQLRETVDENGRLYKLLKERDFEIKHLKKKIEEDRFAFTGTAGVAGDVIATKIVELSKKNRVLMAESEGAKTRVRQLSNRIQELEQELQIAQARLPAKGSTDAGAKPPRTQMGDRVLPENPEVKVLQDRLAATNLKMSDLRNQIQAVKQELRMAQKVLTSEVGEDVNIQQLLSSPGTWRGRAQQILVLQSKVRELEKQLGQTRSRSEETASELSVYPDSRKLSAQEKNLLRIRNLEREKQEGWEKLSAERDALQRELEELKKKFEGMRSRNKVLSSEVKTLRSQMGTLVEKGRHDDELIDALMDQLKQLQEILGSLSLQEEKTRVSQHRLDQQLNSEAQRSSSLVAQLRAMVAEREAKVQQLELEIGQLSVQYLRNKGVDEGSSGPEVSRASTKLPEDPGLTKPPASAGDHAGRLGSSRSVTSLGHTLVESSLTWPSLPSPHGASPRFLDSPEQKGWQTQVTEFKALWQAAEVERDRLTEFVTVLQKRVEERNSKLLESERRLQEERHRAVVLEQHLEKMRLEPGRMSASQRAAPRSKTGLPASNTRHHPSESERKDPSSAQLSSVPMESQMEELTTRLAIQVEENEMLKAALGNALQGKEEDFRMYHETLDQVKGVFLQALRQQKADKH", "length": 714, "header": "tr|E1BLG9-1|E1BLG9_BOVIN Isoform 1 of Coiled-coil domain containing 13 OS=Bos taurus OX=9913 GN=CCDC13 PE=4 SV=3 CANONICAL=E1BLG9-1" }, "isoforms": [ { "isoform_ac": "E1BLG9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLG9/entry#E1BLG9-1", "sequence": 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"database": "Ensembl Transcript", "id": "ENSBTAT00000017304.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017304.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017304.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017304.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538960", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538960", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E1BLG9", "url": "https://www.uniprot.org/uniprotkb/E1BLG9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centriolar satellite", "id": "GO:0034451", "url": 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"evidence": [ { "id": "E1BLJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9" } ] }, { "name": "SV2C", "type": "synonym", "evidence": [ { "id": "NP_001178948", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178948" } ] } ], "protein_names": [ { "name": "Synaptic vesicle glycoprotein 2C", "type": "synonym", "evidence": [ { "id": "E1BLJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9/entry#names_and_taxonomy" } ] }, { "name": "synaptic vesicle glycoprotein 2C", "type": "synonym", "evidence": [ { "id": "NP_001178948", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178948" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLJ9", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SV2C", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9", "locus": { "chromosome": "10", "start_pos": 7575348, "end_pos": 7361640, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017507", "url": "https://www.ensembl.org/id/ENSBTAG00000017507" } ] } } ], "crossref": [ { "id": "E1BLJ9", "url": "https://alphafold.ebi.ac.uk/entry/E1BLJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017507", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017507", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538430", "url": "https://www.ncbi.nlm.nih.gov/gene/538430", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538430", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538430", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HDEYKDR", "url": "https://omabrowser.org/oma/group/HDEYKDR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BLJ9", "url": "https://www.orthodb.org/?gene=E1BLJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23511", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23511", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23511:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23511:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178948", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178948", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BLJ9", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLJ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDSYKDRTSLMKGAKDIAREVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEEEDDDIYPPGETYNGEANDDEGSSEATEGHDEDDEIYEGEYQGIPSMNQGKDSIVSVGQPKGDEYKDRQELESERKADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSINGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCASSVVALTFMPESPRFLLEIGKHDEAWMILKLIHDTNMRARGQPEKVFTVNRIKTPRQIDELIEIESDTGTWFRRCSVRIRTELYGIWLTFMRCFTYPVRENTIKLTIVWFTLSFGYYGLSVWFPDVIKHLQSNVLKNVDEPKVKFSNATINFTMANQIITGMECDNGRFAGIRFKSITFENSVFKSCTFEDVTSVNTYFKNCTFIETVFNKTDFEPYKFINCRFQNSTFLYNKTGCQFTFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKAIPILLASTVLVCGGLVGLRLPDTRTQVLM", "length": 725, "header": "tr|E1BLJ9-1|E1BLJ9_BOVIN Isoform 1 of Synaptic vesicle glycoprotein 2C OS=Bos taurus OX=9913 GN=SV2C PE=3 SV=1 CANONICAL=E1BLJ9-1" }, "isoforms": [ { "isoform_ac": "E1BLJ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9/entry#E1BLJ9-1", "sequence": { "sequence": "MEDSYKDRTSLMKGAKDIAREVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEEEDDDIYPPGETYNGEANDDEGSSEATEGHDEDDEIYEGEYQGIPSMNQGKDSIVSVGQPKGDEYKDRQELESERKADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSINGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCASSVVALTFMPESPRFLLEIGKHDEAWMILKLIHDTNMRARGQPEKVFTVNRIKTPRQIDELIEIESDTGTWFRRCSVRIRTELYGIWLTFMRCFTYPVRENTIKLTIVWFTLSFGYYGLSVWFPDVIKHLQSNVLKNVDEPKVKFSNATINFTMANQIITGMECDNGRFAGIRFKSITFENSVFKSCTFEDVTSVNTYFKNCTFIETVFNKTDFEPYKFINCRFQNSTFLYNKTGCQFTFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKAIPILLASTVLVCGGLVGLRLPDTRTQVLM", "length": 725, "header": "tr|E1BLJ9-1|E1BLJ9_BOVIN Isoform 1 of Synaptic vesicle glycoprotein 2C OS=Bos taurus OX=9913 GN=SV2C PE=3 SV=1 CANONICAL=E1BLJ9-1" }, "locus": { "chromosome": "10", "start_pos": 7574344, "end_pos": 7411312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036622.4", "url": "https://www.ensembl.org/id/ENSBTAT00000036622.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036478.2", "url": "https://www.ensembl.org/id/ENSBTAP00000036478.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538430", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538430", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BIS0-1", "protein_name": "Synaptic vesicle glycoprotein 2C", "gene_name": "SV2C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDSYKDRTSLMKGAKDIAREVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEEEDDDYPPGETYNGEANDDEGSSEATEGHDEDDEIYEGEYQGIPNTNQGKDSIVSVGPPKGGEYKDRQELESERKADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPDSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSINGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNRIKTPRQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFTYPVRENTIKLTIVWFTLSFGYYGLSVWFPDVIKHLQPNVLKNTNDPRVTFSDFTINFTMANQINIGMEYENGRFEGIRMKSVTFKDSVFKSCTFKDVTSVNTYFKNCTFIDTVFNNTDFEPYKFINSVFQNCSFSNNKTGCPITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSQSMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKAIPILLASTVLVCGGLVGLRLPDTRTQVLM", "length": 724 }, "evidence": [ { "id": "E1BLJ9", "url": "https://omabrowser.org/oma/group/E1BLJ9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1NCT9-1", "protein_name": "Synaptic vesicle glycoprotein 2C", "gene_name": "SV2C", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEESYKDRTSLVKGAKDIAKEVKRQAVKKVNKAVDKAQDGYTQRSYSRFQDEEDDDDYYVQGGNYGAEANDDEGSSEATEGHDEDDEIYEGEYQGIPNMGQGKDGMVALGQPVRDEYKDRHELETERKADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDMCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRRQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLFSGFGIGGAVPTVFSYFSEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEIGKHDEAWMILKQIHDTNMRARGQPEKVFTVNRIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVKDNTIKLTIVWFTLSFGYYGLSVWFPDVIKHLQSDKYASQVKVFRNEEVSNFVFNFTLKNQIHSSGEYVNDRFVMMKFKSVTFEDSLFKNCVFEDITSMNTYFRNCTFVNTTFYNTDFEQYKFVDSDFINCTFFHIRTGCQISFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVITVELYPTDRRATSFGFLNALCKAAAVLGNLIFGSLVGITKAIPILLASTVLVCGGLVGLRLPDTRTQVLM", "length": 727 }, "evidence": [ { "id": "E1BLJ9", "url": "https://omabrowser.org/oma/group/E1BLJ9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q496J9-1", "protein_name": "Synaptic vesicle glycoprotein 2C", "gene_name": "SV2C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDSYKDRTSLMKGAKDIAREVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEEDDDDYYPAGETYNGEANDDEGSSEATEGHDEDDEIYEGEYQGIPSMNQAKDSIVSVGQPKGDEYKDRRELESERRADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRDNTIKLTIVWFTLSFGYYGLSVWFPDVIKPLQSDEYALLTRNVERDKYANFTINFTMENQIHTGMEYDNGRFIGVKFKSVTFKDSVFKSCTFEDVTSVNTYFKNCTFIDTVFDNTDFEPYKFIDSEFKNCSFFHNKTGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKSIPILLASTVLVCGGLVGLCLPDTRTQVLM", "length": 727 }, "evidence": [ { "id": "E1BLJ9", "url": "https://omabrowser.org/oma/group/E1BLJ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q69ZS6-1", "protein_name": "Synaptic vesicle glycoprotein 2C", "gene_name": "Sv2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSYKDRTSLMKGAKDIAKEVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEEDDDDYYPPGETYSGEVNDDEGSSEATEGHDEEDEIYEGEYQGIPSTNQGKDSIVSVGQPKGDEYKDRRELESERRADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLVCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRENTIKLTIVWFTLSFGYYGLSVWFPDVIKHLQSDEYALLTRNVQKDKYANFSINFTMENQIHTGMEYENGRFLGVKFKSVTFKDSVFKSCTFDDVTSVNTYFKNCTFIDTLFDNTDFEPYKFIDSEFQNCSFLHNKTGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKAIPILLASTVLVCGGLVGLRLPDTRTQVLM", "length": 727 }, "evidence": [ { "id": "E1BLJ9", "url": "https://omabrowser.org/oma/group/E1BLJ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z2I6-1", "protein_name": "Synaptic vesicle glycoprotein 2C", "gene_name": "Sv2c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDSYKDRTSLMKGAKDIAKEVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEDDDDDYYPPGETYSGEANDDEGSSEATEGHDEEDEIYEGEYQGIPSTNQGKDSIVSVGQPKGDEYKDRRELESERRADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLLCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRENTIKLTIVWFTLSFGYYGLSVWFPDVIKHLQSDEYALLTRNVQKDKYANFSINFTMENQVHTGMEYDNGRFLGVKFKSVTFKDSVFKSCTFDDVTSVNTYFKNCTFIDTLFENTDFEPYKFIDSEFQNCSFLHNKTGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKAIPILLASTVLVCGGLVGLRLPDTRTQVLM", "length": 727 }, "evidence": [ { "id": "E1BLJ9", "url": "https://omabrowser.org/oma/group/E1BLJ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BLJ9", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "E1BLJ9", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9" } ], "pmid": "" }, { "name": "dopaminergic synapse", "id": "GO:0098691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098691", "evidence": [ { "database": "UniProtKB", "id": "E1BLJ9", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "E1BLJ9", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "E1BLJ9", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9" } ], "pmid": "" }, { "name": "neurotransmitter transport", "id": "GO:0006836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006836", "evidence": [ { "database": "UniProtKB", "id": "E1BLJ9", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle exocytosis", "id": "GO:2000300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000300", "evidence": [ { "database": "UniProtKB", "id": "E1BLJ9", "url": "https://www.uniprot.org/uniprotkb/E1BLJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 478, "end_pos": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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[ { "database": "Ensembl Gene", "id": "ENSBTAG00000015983", "url": "https://www.ensembl.org/id/ENSBTAG00000015983" } ] } } ], "crossref": [ { "id": "E1BLN3", "url": "https://alphafold.ebi.ac.uk/entry/E1BLN3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015983", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015983", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "780976", "url": "https://www.ncbi.nlm.nih.gov/gene/780976", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:780976", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:780976", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242:SF388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242:SF388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377211", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377211", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BLN3", "url": "https://www.uniprot.org/uniprotkb/E1BLN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLN3-1", "url": "https://www.uniprot.org/uniprotkb/E1BLN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNVSGVNTVTEFILLSFPCSREVQVLLFVLFSVSYILTLMGNGAIVFAVKLDHRLHTPMYTLLANFSFLEMCYINTTVPNMLRNFLSETKTISFTACFLQFYFFFSVGTTETFLLPLMAFDRYLAICRPLHYPTIMSSCLCMNLVGLCWVTAFLCYPVPIYFITQLPFCGPNTIDHFVCDPGPLLALSCTSAPGIELSCSILSSLIIFITFFFILGSYTLVLRAVLRVPSASGRRKAFSTCGSHLVVVSLFYGTLMVMYICPTSGKPAGIQKIVTLFYSSLTPLVNPLIYSLRNKDMKAALRKIQKCTKISQSE", "length": 314, "header": "tr|E1BLN3-1|E1BLN3_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR11G9 PE=3 SV=3 CANONICAL=E1BLN3-1" }, "isoforms": [ { "isoform_ac": "E1BLN3-1", "url": "https://www.uniprot.org/uniprotkb/E1BLN3/entry#E1BLN3-1", "sequence": { "sequence": "MNVSGVNTVTEFILLSFPCSREVQVLLFVLFSVSYILTLMGNGAIVFAVKLDHRLHTPMYTLLANFSFLEMCYINTTVPNMLRNFLSETKTISFTACFLQFYFFFSVGTTETFLLPLMAFDRYLAICRPLHYPTIMSSCLCMNLVGLCWVTAFLCYPVPIYFITQLPFCGPNTIDHFVCDPGPLLALSCTSAPGIELSCSILSSLIIFITFFFILGSYTLVLRAVLRVPSASGRRKAFSTCGSHLVVVSLFYGTLMVMYICPTSGKPAGIQKIVTLFYSSLTPLVNPLIYSLRNKDMKAALRKIQKCTKISQSE", "length": 314, "header": "tr|E1BLN3-1|E1BLN3_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR11G9 PE=3 SV=3 CANONICAL=E1BLN3-1" }, "locus": { "chromosome": "10", "start_pos": 26867686, "end_pos": 26866745, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052513.4", "url": "https://www.ensembl.org/id/ENSBTAT00000052513.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050316.3", "url": "https://www.ensembl.org/id/ENSBTAP00000050316.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 263, "start_aa": "Thr", "end_pos": 263, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr263", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:780976", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:780976", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BLN3", "url": "https://www.uniprot.org/uniprotkb/E1BLN3" } ], "pmid": "" }, { "name": "olfactory receptor 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"end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLN3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLN3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLN3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 263 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 2, "end_pos": 4 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLN7-1", "uniprot_ac": "E1BLN7", "uniprot_id": "E1BLN7_BOVIN", "mass": { "chemical_mass": 124922.0, "monoisotopic_mass": 124922.0 }, "refseq": { "ac": "NP_001192369", "name": "protein phosphatase 1 regulatory subunit 3A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192369" }, "gene_names": [ { "name": "PPP1R3A", "type": "recommended", "evidence": [ { "id": "E1BLN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLN7" } ] }, { "name": "PPP1R3A", "type": "synonym", "evidence": [ { "id": "NP_001192369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192369" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 3A", "type": "recommended", "evidence": [ { "id": "E1BLN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLN7/entry#names_and_taxonomy" } ] }, { "name": "Protein phosphatase 1 glycogen-associated regulatory subunit", "type": "synonym", "evidence": [ { "id": "E1BLN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLN7/entry#names_and_taxonomy" } ] }, { "name": "Protein phosphatase type-1 glycogen targeting subunit", "type": "synonym", "evidence": [ { "id": "E1BLN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLN7/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 3A", "type": "synonym", "evidence": [ { "id": "NP_001192369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192369" } ] }, { "name": "protein phosphatase 1, regulatory (inhibitor) subunit 3A", "type": "synonym", "evidence": [ { "id": "NP_001192369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192369" } ] } ], "function": [ { "annotation": "Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.", "evidence": [ { "database": "UniProtKB", "id": "E1BLN7", "url": "https://www.uniprot.org/uniprotkb/E1BLN7#function" }, { "database": "UniProtKB", "id": "ARBA00058944", "url": "https://www.uniprot.org/uniprotkb/ARBA00058944#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLN7", "url": "https://www.uniprot.org/uniprotkb/E1BLN7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PPP1R3A", "url": "https://www.uniprot.org/uniprotkb/E1BLN7", "locus": { "chromosome": "4", "start_pos": 54592009, "end_pos": 54551942, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006733", "url": "https://www.ensembl.org/id/ENSBTAG00000006733" } ] } } ], "crossref": [ { "id": "E1BLN7", "url": "https://alphafold.ebi.ac.uk/entry/E1BLN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006733", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006733", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22255", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22255", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "784877", "url": "https://www.ncbi.nlm.nih.gov/gene/784877", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:784877", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784877", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DCWELPS", "url": "https://omabrowser.org/oma/group/DCWELPS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BLN7", "url": "https://www.orthodb.org/?gene=E1BLN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12307", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12307", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12307:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12307:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192369", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192369", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BLN7", "url": "https://www.uniprot.org/uniprotkb/E1BLN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLN7-1", "url": "https://www.uniprot.org/uniprotkb/E1BLN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPSEEPSQISKDNFLEVPSLSDSLSEDEEVKATFRPGFSPQPSRRGSESSEDLYLDSPPSGARRVSFADTFGLNLVSVKEFDSWELPSGSADFDLRQDVFHTEEYVLSPQFGLPSSKEDLMQQLQVQKAILESTEYPPGSTSMKGIIRVLNVSFEKLVYVRMSLDDWQSYYDILAEYIPNSCDGETDQFSFKISLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYVLICQKKEQEPEPEKLQEDVPNRQIKGCLKVKSSKEESSVTSDENNFENSKVTDTYIPTIVCSHEDKEDLETSNQNVKDVNREQDERNEKELEPMINQHLLRSTASGDEKNTVNFPNNAERLEKKQIHDDVYTDLFKRPSSSSSSAERSLKGDFYHKEKYFSGNEHTYPPSEEFTSDTGEIKLSLGNTSSDEVVQLHIGSKEVLDDNANPAKGRGRVQMSCPSADQLMADNLNKKLEGEAKEIEVKDWECLRGDFRLDFHSEKSIEKGSSKKDYGNGKNEEEEQKIYLGVSEKQSKSFQSVLHDQERKMSHSEISVEGMGASNRDLTALPSKDTKIHDQSIRADTFHSPRTNLSLEETVSATSDSDLSASKGTALGGMPGQAGSPRNANVLRNKYLFQAEEEKSVWINPEDQNKNTQHKQSWNVLESQERARGSKTTITEQSKEQADCEDTWGKRDDTRSLKANPTEELFTCQETASCELSSLADHGITEKADAGTAYIIKTTSESTLECMSAREKAIIAKLPQETAQSDRPIEVKETAFDPHEGRNDDSHNTLCQRDTVGVIYDNDFEKESCSGICNVHVDEKEKEETIAIYNPGETHDRKKCVIGNTTSGEESSQVITDNQKAASKLDLHLGMLPTDKKIFPENRDHEQVQELSKKTIIDVIIHSSLNSDTNRTSQNGSQVSNHHAKSSVSSHEQATTTGHAITTMTLQSISSKSEYNCNPTSEIQGTEKHSHPASPLEEVSESSGIVTSDSTKERCIGQIVKQGECSVEKPLGPTILISEASENIEGVRHENEGLINSGQSLYSSGDKESDSPASDSLPAQESQSQSESLLSKYINSKVPYFLLFLIFLVTIYQYDLMIGLAFYLFSLYWLSWEGGRQKESVKKK", "length": 1117, "header": "tr|E1BLN7-1|E1BLN7_BOVIN Isoform 1 of Protein phosphatase 1 regulatory subunit 3A OS=Bos taurus OX=9913 GN=PPP1R3A PE=4 SV=3 CANONICAL=E1BLN7-1" }, "isoforms": [ { "isoform_ac": "E1BLN7-1", "url": "https://www.uniprot.org/uniprotkb/E1BLN7/entry#E1BLN7-1", "sequence": { "sequence": "MEPSEEPSQISKDNFLEVPSLSDSLSEDEEVKATFRPGFSPQPSRRGSESSEDLYLDSPPSGARRVSFADTFGLNLVSVKEFDSWELPSGSADFDLRQDVFHTEEYVLSPQFGLPSSKEDLMQQLQVQKAILESTEYPPGSTSMKGIIRVLNVSFEKLVYVRMSLDDWQSYYDILAEYIPNSCDGETDQFSFKISLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYVLICQKKEQEPEPEKLQEDVPNRQIKGCLKVKSSKEESSVTSDENNFENSKVTDTYIPTIVCSHEDKEDLETSNQNVKDVNREQDERNEKELEPMINQHLLRSTASGDEKNTVNFPNNAERLEKKQIHDDVYTDLFKRPSSSSSSAERSLKGDFYHKEKYFSGNEHTYPPSEEFTSDTGEIKLSLGNTSSDEVVQLHIGSKEVLDDNANPAKGRGRVQMSCPSADQLMADNLNKKLEGEAKEIEVKDWECLRGDFRLDFHSEKSIEKGSSKKDYGNGKNEEEEQKIYLGVSEKQSKSFQSVLHDQERKMSHSEISVEGMGASNRDLTALPSKDTKIHDQSIRADTFHSPRTNLSLEETVSATSDSDLSASKGTALGGMPGQAGSPRNANVLRNKYLFQAEEEKSVWINPEDQNKNTQHKQSWNVLESQERARGSKTTITEQSKEQADCEDTWGKRDDTRSLKANPTEELFTCQETASCELSSLADHGITEKADAGTAYIIKTTSESTLECMSAREKAIIAKLPQETAQSDRPIEVKETAFDPHEGRNDDSHNTLCQRDTVGVIYDNDFEKESCSGICNVHVDEKEKEETIAIYNPGETHDRKKCVIGNTTSGEESSQVITDNQKAASKLDLHLGMLPTDKKIFPENRDHEQVQELSKKTIIDVIIHSSLNSDTNRTSQNGSQVSNHHAKSSVSSHEQATTTGHAITTMTLQSISSKSEYNCNPTSEIQGTEKHSHPASPLEEVSESSGIVTSDSTKERCIGQIVKQGECSVEKPLGPTILISEASENIEGVRHENEGLINSGQSLYSSGDKESDSPASDSLPAQESQSQSESLLSKYINSKVPYFLLFLIFLVTIYQYDLMIGLAFYLFSLYWLSWEGGRQKESVKKK", "length": 1117, "header": "tr|E1BLN7-1|E1BLN7_BOVIN Isoform 1 of Protein phosphatase 1 regulatory subunit 3A OS=Bos taurus OX=9913 GN=PPP1R3A PE=4 SV=3 CANONICAL=E1BLN7-1" }, "locus": { "chromosome": "4", "start_pos": 54591614, "end_pos": 54551942, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008851.6", "url": "https://www.ensembl.org/id/ENSBTAT00000008851.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008851.5", "url": "https://www.ensembl.org/id/ENSBTAP00000008851.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:784877", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784877", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IIM0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3A", "gene_name": "Ppp1r3a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPAEEPGQISKDNFLEVPNVSDSVCEDEEVKATFKPGFSPQPSRRGSGSSEDTYLDTPTSASRRVSFADSLGFNLVSIKEFDCWELPSVSTDFGLSRDIFHTEEYILSPLFDLPSSKEELMEQLQVQKAMLESTEYLPGSTSVKGIIRVLNISFEKLVYVRMSLDAWQTHYDILAEYVPNSCDGKTDQFSFKISLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYVLVCQKKKKEPEPVKPLEEAPNRQIKGCLKVKSSSKEESSLTSEENKLETFKFTDAYVPTIICSHEDKDDLGASHQNVEDINREHDGHNEKELDLMIHPPLIISRDEKNTFSTDSVNWTNKAEGSEKKQEYHEIHTGLFRRQLSPSLPEEISLKKDSYHSRNYSPGNEYGHPPSEEIMSHAGEMEQLLGDSSADELMQQNLCSQEVLDDNANPAHGSDKVQIACSSYDHLMTDGLNKNNETGVKKTGIKDHKYSRSDFYLEASTNLEESNASPKDDYTKGNDEEEENTCLGVNENQRKNFQSVFHNQERQMGHPEISIEGTKASNEDLTTLLSKDTTTTTWRARVDLSPSTKTKVNWRETGKGTTLEPIATHLGSPRNGNVLTGSYLLQAAREKSDPSNPEDQNMNTQYKKNWNVLESQPETRGIETNTAKQIKEQAECKDMWEKRDNKRSLKATPTEPLFTCQETECYELSSLADHGITEKAQAVTAYIIKTTLERTPESMSARGNTIIAKLPQETARSDRPIEVKETAFDPHEGRKDDSHYTLCHGDTAGVIHDNDFERESHLAVCDVHVEEMEKEATTSTCYPRKTHDKEKCGIGIVTSTDKSSEVITGNHKATSKLDLHLGVLPTDKAIFPENKDHELLEELSRRTDFDAVHPEFNSDASSTSQGSPQVYRCQSKNSEPTSGWLFAEDNAGTSTTLRSILTKSEYTCCPESETLGHAMSKPDDVSKTLEITESGNGRERPVGPILQQKEGKSMQKSQGPIILVSEPLENLEEAKSDIEGLIHFEQSQRYLDDTGSESPPSATLPPQEAQAQGRESLLSTYVNSKLPYFLLFLIFLATIYYYDLMVGLAFYLFSLYWLYWEGGRHKESVKKK", "length": 1104 }, "evidence": [ { "id": "E1BLN7", "url": "https://omabrowser.org/oma/group/E1BLN7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0X902-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3A", "gene_name": "PPP1R3A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MESFEGPSRVSKANLLEVPTVNDFFSEDEDVKPDIKHRFSPLPRRRNSASSEEEEADAPTTIARKVSFADAFGFDLVSVKEFDTWEIPNIAQNNDLEDEAFPQEEFFLTQLFTLPTSQEEVLQKVREHKVLLESIVFLPGITCMNGIIRVLNVSFEKFVYVRMTLDDWVSYYDILAEFMPNSCGSETDQFCFKISLVPPYQRDGAKVEFCIRYETSIGTFWANNDDKNYTLICHKKETVPKLDNKPHKEAADRHLKGCLKTAPSSKEELLATSDGDIWNNSRTSDANIPEIVCSQAEDKENAPANENIKDKNAEYNQGDQEDDEKELELLLNQHFTGAKGTSSRDERNLDTTEPVNFPSETVRLEKNLTCVERSSDLLRHPVPISSLSENTSQVIGEELKGNAKYSIGGYNSHPSGKEVSAGSANSSEQSWDSTGISETLSSAKYFPGTKQNEAINIAATVSSRQGESHTDITRCEADSASGSKMMERLFISEDDTSKETCEMRPEAISSSHDESLQLKACITGTLDGNANPAPEHQLPKMSHQTLDSLSSAADKSEGKIEMIESKVQAHLRGDLHTDTFAYTDVSVDSTKSQYSHQKGVGELSEKNYSTDTEKEKRVIEIADLALIGEEEAPRPFKPHRKHAFSASFLSDEDNKHRARPAQAGPGAYLPEDESRAEDAQEHRGFTRLKDRGKTENGNKGGLIGTESEENTTGQAWKRADSGVRWAAGGDARGQSSCTKESFICQEAESREKSSVSEHDIKGKAEAGMAYIIKTTSESAPEKMSASEKAVIAKLPQEIALSDRPTEEKETAFDTHEGRNDGSHALCQLNTVGVLYDTEFEKESVLDIYNARVHETLQGETMSVCNSGEKRAKAKPDIGDIPPAEGAVKASSAGKKEGLGQGLHSEEVSKYSQSAQKHRYSEELAELYSEESYLGTPSYLHVKAQTKTSTSGTNTMPSYHYKSPPLASSAADTDHPYIHSEFKVIEKVAESGYDLSLPNEMKHISKSLFPEAERKEVPSTSDTTVAREGRGSSIGQCFHQAEFKQEKSLRPEISISKATKEVAGRGSDSHHLITEGKTLSWLDDSQNEKQNVSHSADMSDQKSEEQMLSSESPSLKQIGCKIFCFFFFLVFAATLYHYDLMVCLALYLFSLYWLYWEGRGSKESVKKD", "length": 1167 }, "evidence": [ { "id": "E1BLN7", "url": "https://omabrowser.org/oma/group/E1BLN7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZM60-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3A", "gene_name": "Ppp1r3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPAEVPGQISKDNFLEVPNLSDSVCEDEEVKATFKPGFSPQPSRRGSESSEDLYLDTPTSASRRVSFADSLGFSLVSVKEFDCWDLPSVSTDFDLTRDVLHTDEYILSPLFDLPSSKEELMEQLQVQKAVLESAEHLPGSTSVKGIIRVLNISFEKLVYVRMSLDDWQTHYDILAEYVPNSCDGETDQFSFKISLVPPYQMDGGKVEFCIRYETSVGTFWSNNNGTNYILVCQKKTKEPEPVVKPLEEGPSRQIKGCLKVKSSSKEEPLLTPEENKLGTLKFTESYIPTIICSHEDRDDLGANYQHVKDIDKKHDEHNEKELDLMINQRLITSHDEKNTFSTDAVNSTNKAEGSEKKQARHEIHTDLCRGPLSPSLSAESSLKRDFYHSRNYSPGNEHGHPPSEEIISDVGAIGSPLGDTSSDELMQLKVCSKEDVDDNANPAHGSGRLCSSSDQLRAGGLENNEAGIKKTGIKDYKYSHGDSYLEASTSLRESNASYKDEYDKVDDKREKKTCLGVNENPGKNFQSIFQNQERQMGCAKISGEGANANNQDLTTLLSKDTTTNTWAVTVDPSPSTNTNVNWREAGNGTDLERRTTDLGSPRNFSLLTDGYLFQADREKSDSSNSEDRNMNPQHKKNWNVLESQPETRETETNITKHTKEQAEYKDTWGKRDNSRNLKATSTEQLFTCQETECCELSSLADHGITEKAQAVAAYIIKTTLESTPESASARGKAIIAKLPQETARHDRPIEVKETAFDPHEGRKDDSHYSLCHGDTAGVIHDNDFERESHLDICNVRVDEMEKEKTTSTCSPRKTYDKEKHGIGSVTSIDEPSQVITGNQKATSKLDLHLGVLPTDRAILSANADLELLQELSRRTDFNAVHSAFNSDPGSASQDSSQVYRRCSKKPVPSYGEQKAVINTTLQSVPTKSEYNCHPESEIFGHATSKPEVVFKSSEIIKSGSGGEQGVGPILQQKEGSLEKSQDPMISINEPLENLDEVRSENEGLMRSGQLQCYLGDKGSVSSASATVPTQELQAQGSESLLSISINSKIPYFLLFLIFLATVYYYDLMIGLAFYLFSLYWLYWEGGRQRESVKKK", "length": 1096 }, "evidence": [ { "id": "E1BLN7", "url": "https://omabrowser.org/oma/group/E1BLN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SJC2-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3A", "gene_name": "PPP1R3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPSEEPSHISKDNFLEVPNLSDSLSEDEEIKANFRPGFSPQPSRRGSDSSEDIYLDTPPPSGARRVSFADTFGFNLVSVKEFDSWELPSSSTDFDLTKDIFHTEEYVLTPLFDLPSSKEDLMQQLQVQKAILESAEYPPGSTSMKGIIRVLNISFEKLVYVRMSLDDWQTYYDILAEYVPNSCDGDTDQFSFKISLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYILVCQKKEQEMEPVKPQEDVPNRHIKGCLKVKSSKEESSVPSEENNFENSKITDTYIPTIVCSDEDKEDLETGNQNVKDVNREHDEHNEKELELMINQHLIRSTASRDEKNIVNFPNKAEGLEKKEIHDEVFTDLFKRPLSSSSSAERSLKGDSYPNEQYPSGNEGSHQPSEGISSDMGEIKPSLGNTSSDELVQLHIGSKEVLDDNANPAQGRGRVKISHLFSDQIMAENCNKKLEEEAKKIEMKDWECLRRDFHSEFHSEESTEKGSSKKDYDSGKNEEEEQRIHLGVNEKQRKKFPSTLHDQERKTGHSEISVEGMGASTRDLTALPSKDTTIHGQAIRADIFHSPRTNLSWEEAVLTTPDCDLSTREGISLGGILGQACSPRNGNVLRNKHLFQAEEEQSDCIKPEDQHKNTQHKQNQNVLESQGKARENRTNITEQTKEQADCEDMWKKRDNTRILKATPTEKLFTCQETASYELSSLADHGITEKVEAGTAYIIKTTSESTLESMSAREKAIIAKLPQETARSDRPIEVKETAFDPHEGRNDSRDNLCQRDTVGVTYDNDFEKESCLGICNVHIDETEKEETISVYNSGKTHDRKKRDVGNTTSVEESSQGIIDNQKADSKLDLHLEMLPIGKKIFTENKDPGQVQELSKKTNIDAVIHSALNSGTNGASQNGSHVSNHHAKNSVPTHEQEAAAENENTTTTPQSISSKSEYNCNPTREIQGIDKHPHPMTTPEDVSKSSGIVTSGSWKERCTGQISQQGECSVETSLGPTILTSEALENKEEARHENEGLINSGQSLCSSGDKESESSASSSLPAQESQAQSSESLLSKYINSKIPYFLLFLIFLVTVYQYDLMIGWAF", "length": 1096 }, "evidence": [ { "id": "E1BLN7", "url": "https://omabrowser.org/oma/group/E1BLN7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q16821-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3A", "gene_name": "PPP1R3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPSEVPSQISKDNFLEVPNLSDSLCEDEEVTFQPGFSPQPSRRGSDSSEDIYLDTPSSGTRRVSFADSFGFNLVSVKEFDCWELPSASTTFDLGTDIFHTEEYVLAPLFDLPSSKEDLMQQLQIQKAILESTESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEYVPNSCDGETDQFSFKIVLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYTFICQKKEQEPEPVKPWKEVPNRQIKGCLKVKSSKEESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEASNRNVKDVNREHDEHNEKELELMINQHLIRTRSTASRDERNTFSTDPVNFPNKAEGLEKKQIHGEICTDLFQRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPSLGDTSSDELVQLHTGSKEVLDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEGGAKNIEVKDLGCLRRDFHSDTSACLKESTEEGSSKEDYYGNGKDDEEQRIYLGVNEKQRKNFQTILHDQERKMGNPKISVAGIGASNRDLATLLSEHTAIPTRAITADVSHSPRTNLSWEEAVLTPEHHHLTSEGSALGGITGQVCSSRTGNVLRNDYLFQVEEKSGGINSEDQDNSPQHKQSWNVLESQGKSRENKTNITEHIKGQTDCEDVWGKRDNTRSLKATTEELFTCQETVCCELSSLADHGITEKAEAGTAYIIKTTSESTPESMSAREKAIIAKLPQETARSDRPIEVKETAFDPHEGRNDDSHYTLCQRDTVGVIYDNDFEKESRLGICNVRVDEMEKEETMSMYNPRKTHDREKCGTGNITSVEESSWVITEYQKATSKLDLQLGMLPTDKTVFSENRDLRQVQELSKKTDSDAIVHSAFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTKSENICNSTREIQGIEKHPYPESKPEEVSRSSGIVTSGSRKERCIGQIFQTEEYSVEKSLGPMILINKPLENMEEARHENEGLVSSGQSLYTSGEKESDSSASTSLPVEESQAQGNESLFSKYTNSKIPYFLLFLIFLITVYHYDLMIGLTFYVLSLSWLSWEEGRQKESVKKK", "length": 1122 }, "evidence": [ { "id": "E1BLN7", "url": "https://omabrowser.org/oma/group/E1BLN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99MR9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3A", "gene_name": "Ppp1r3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPAEEPGQISKDNFLEVPNLSDSVCEDEEVKATFKPGFSPQPSRRGSGSSEDMYLDTPTSASRRVSFADSLGFSLVSVKEFDCWELPSVSTDFDLSGDVFHTDEYVLSPLFDLPSSKEKLMEQLQVQKAVLESAEHLPGSSMKGIIRVLNISFEKLVYVRMSLDDWQTHYDILAEYVPNSCDGETDQFSFKISLVPPYQKEGGKVEFCIRYETSAGTFWSNNNGTNYILVCQKKRKEPEPVKPLEEAPSRQIKGCLKVKSRSKEEPLLAPEENKFETLKFTESYIPTIICSHEDKDDLGANHPNVDDINKKHDEHNGKELDLMINQRLITSQDEKNTFATDTVNFTNKAEGSEKKQAYHEINTDLFMGPLSPSLSAESSLKRDFYHSRSSSPGNEYGHPHSEEIISDMGEKGPSLGDTSSDELMQLELCSKEDLDDNANPANGSGRVCSSFDQRMACGLKNNEAGIKKTGIQDYKYSHGDSTKLEESNASSRDDYAKVDNKKEKQTCLGVNENPSKNFQSVFQTQEGHMGYPKISTEGDKANNQDLTSLLSKDITANTWAVTVDPCPSTNAKRSWREVGSGSNLEPGTSDLSSPRNFSPLTDDHLFQADRENSDSSNPENQNMNTRHRKKWNVLETQSETSETESDIAKHTKEQAEYKDMWEKTDNSRNLKATPTEHLFTCRETECYGLSSLADHGITEKAQAVTAYIIKTTLESTPESASARGKAIIAKLPQETAGNDRPIEVKETAFDPHEGRKDDSHYSLCHGDTAGVIHDNDFERESHLDICNLRVDEMKKEKTTSTCFPQKTYDKEKHGIGSVTSIDEPSQVITGNQKATSKLDLHLGVLPTDRAIFQANADLELLQELSRRTDFNAVPSAFNSDTASASRDSSQVYRHCSKKSVPSYGEEKAVTNTTLQSIPTKSEYNWHPESEVLGHAMSKPEDVFKSSEIMKSGSGGERGGGPILQQKEGSLENSQGPMFFTNEPLENLDEASSENEGLMHSGQSQCYLGDKGLVSSASATVSTQELEAQGRESLLSISTNSKIPYFLLFLIFLATVYYYDLMIGLAFYLFSLYWLYWEGGRQRESVKKK", "length": 1089 }, "evidence": [ { "id": "E1BLN7", "url": "https://omabrowser.org/oma/group/E1BLN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "protein phosphatase type 1 complex", "id": "GO:0000164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000164", "evidence": [ { "database": "UniProtKB", "id": "E1BLN7", "url": "https://www.uniprot.org/uniprotkb/E1BLN7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BLN7", "url": "https://www.uniprot.org/uniprotkb/E1BLN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycogen metabolic process", "id": "GO:0005977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005977", "evidence": [ { "database": "UniProtKB", "id": "E1BLN7", "url": "https://www.uniprot.org/uniprotkb/E1BLN7" } ], "pmid": "" }, { "name": "regulation of glycogen biosynthetic process", "id": "GO:0005979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005979", "evidence": [ { "database": "UniProtKB", "id": "E1BLN7", "url": "https://www.uniprot.org/uniprotkb/E1BLN7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "E1BLN7", "url": "https://www.uniprot.org/uniprotkb/E1BLN7" } ], "pmid": "" }, { "name": "glycogen binding", "id": "GO:2001069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001069", "evidence": [ { "database": "UniProtKB", "id": "E1BLN7", "url": "https://www.uniprot.org/uniprotkb/E1BLN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 837, "end_pos": 839, "annotation": "n_glycosylation_sequon" }, { "start_pos": 903, "end_pos": 905, "annotation": "n_glycosylation_sequon" }, { "start_pos": 908, "end_pos": 910, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLN7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1117, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLN7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLN7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLN7" }, { "id": "PS51159", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBM21", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 232, "start_aa": "Gln", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 581, "end_pos": 583 }, { "start_pos": 837, "end_pos": 839 }, { "start_pos": 903, "end_pos": 905 }, { "start_pos": 908, "end_pos": 910 } ] }, "class_list": [], "section_stats": [ { "table_id": 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"MAPRTPWVGQAAGTRGGWGVIYLVVSLLLQHPGVHSKCYFQAQAPCHYEGKYFTLGESWLRKDCFHCTCLHPVGVGCCDTSQHPIDFPAGCEVRQEAGTCQFSLVQKSDPRLPCKGGGPDPEWGSANTPVPAAPAPHSS", "length": 139, "header": "tr|E1BLN8-1|E1BLN8_BOVIN Isoform 1 of Beta-microseminoprotein OS=Bos taurus OX=9913 GN=MSMP PE=3 SV=1 CANONICAL=E1BLN8-1" }, "isoforms": [ { "isoform_ac": "E1BLN8-1", "url": "https://www.uniprot.org/uniprotkb/E1BLN8/entry#E1BLN8-1", "sequence": { "sequence": "MAPRTPWVGQAAGTRGGWGVIYLVVSLLLQHPGVHSKCYFQAQAPCHYEGKYFTLGESWLRKDCFHCTCLHPVGVGCCDTSQHPIDFPAGCEVRQEAGTCQFSLVQKSDPRLPCKGGGPDPEWGSANTPVPAAPAPHSS", "length": 139, "header": "tr|E1BLN8-1|E1BLN8_BOVIN Isoform 1 of Beta-microseminoprotein OS=Bos taurus OX=9913 GN=MSMP PE=3 SV=1 CANONICAL=E1BLN8-1" }, "locus": { "chromosome": "8", "start_pos": 59922048, "end_pos": 59921096, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056113.3", "url": "https://www.ensembl.org/id/ENSBTAT00000056113.3" }, { "database": "Ensembl Peptide", "id": 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Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002683770", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002683770", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BLN9", "url": "https://www.uniprot.org/uniprotkb/E1BLN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLN9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRENQSSMSEFLLLGLPIQPEQKGVFFALFLGVYLATVLGNLLILLVIRLDPHLHTPMYFFLSHLAFIDITFSSVTTPKMLMNMQTQSQSISYAGCISQVYFFLMLGCLDSFLLTSMAYDRYVAICHPLHYITIMSQSLCFLLVIVSWVLSSASAILHTLLLAHLSFCGDNLLPHFFCDLATLLKLSTSDTTVNELFILTVGVVVITLPFACILVSYGCIGATILRVPSTKGLYKALSTCGSHLSVVALYYGTIIGLYFFPSSNNSNDKDVIVAILYTLITPMLNPFIYSLRNQDMKGALGNILSRGRFS", "length": 311, "header": "tr|E1BLN9-1|E1BLN9_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1J26 PE=3 SV=3 CANONICAL=E1BLN9-1" }, "isoforms": [ { "isoform_ac": "E1BLN9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLN9/entry#E1BLN9-1", "sequence": { "sequence": "MGRENQSSMSEFLLLGLPIQPEQKGVFFALFLGVYLATVLGNLLILLVIRLDPHLHTPMYFFLSHLAFIDITFSSVTTPKMLMNMQTQSQSISYAGCISQVYFFLMLGCLDSFLLTSMAYDRYVAICHPLHYITIMSQSLCFLLVIVSWVLSSASAILHTLLLAHLSFCGDNLLPHFFCDLATLLKLSTSDTTVNELFILTVGVVVITLPFACILVSYGCIGATILRVPSTKGLYKALSTCGSHLSVVALYYGTIIGLYFFPSSNNSNDKDVIVAILYTLITPMLNPFIYSLRNQDMKGALGNILSRGRFS", "length": 311, "header": "tr|E1BLN9-1|E1BLN9_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1J26 PE=3 SV=3 CANONICAL=E1BLN9-1" }, "locus": { "chromosome": "11", "start_pos": 93583456, "end_pos": 93582524, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052043.3", "url": "https://www.ensembl.org/id/ENSBTAT00000052043.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050311.3", "url": "https://www.ensembl.org/id/ENSBTAP00000050311.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514546", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514546", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HLF1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100766603", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRNTRNQSSTSEFILLGLPIRPEDQGLYSALFLVTYLTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQSISYAGCISQVYFFLFFADLDSFLLTSMAYDRYVAICHPLHYTRIMSQSVCILLVIASWFLSFAGALVHTVLLARLSFFRGNTLHHFFCDLSALIKLSSSDTSINELVILIVGSLVITVPFICILVSYGHIGATILRTPSIKGICKALSTCGSHLSVVSLYYGAIIGLYFVPSSNNTNDKDVIVAVLYTMVTPMLNPFIYSLRNRDMKGALWNMLAKATFSM", "length": 313 }, "evidence": [ { "id": "E1BLN9", "url": "https://omabrowser.org/oma/group/E1BLN9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BLN9", "url": "https://www.uniprot.org/uniprotkb/E1BLN9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "E1BLN9", "url": "https://www.uniprot.org/uniprotkb/E1BLN9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BLN9", "url": "https://www.uniprot.org/uniprotkb/E1BLN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BLN9", "url": "https://www.uniprot.org/uniprotkb/E1BLN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLN9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLN9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLN9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLN9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLP0-1", "uniprot_ac": "E1BLP0", "uniprot_id": "E1BLP0_BOVIN", "mass": { "chemical_mass": 75675.0, "monoisotopic_mass": 75675.0 }, "refseq": { "ac": "XP_002688937", "name": "PML-RARA-regulated adapter molecule 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688937" }, "gene_names": [ { "name": "PRAM1", "type": "recommended", "evidence": [ { "id": "E1BLP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLP0" } ] }, { "name": "PRAM1", "type": "synonym", "evidence": [ { "id": "XP_002688937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688937" } ] } ], "protein_names": [ { "name": "PML-RARA-regulated adapter molecule 1", "type": "recommended", "evidence": [ { "id": "E1BLP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLP0/entry#names_and_taxonomy" } ] }, { "name": "PML-RARA-regulated adapter molecule 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002688937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688937" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLP0", "url": "https://www.uniprot.org/uniprotkb/E1BLP0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRAM1", "url": "https://www.uniprot.org/uniprotkb/E1BLP0", "locus": { "chromosome": "7", "start_pos": 17099685, "end_pos": 17108557, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021041", "url": "https://www.ensembl.org/id/ENSBTAG00000021041" } ] } } ], "crossref": [ { "id": "E1BLP0", "url": "https://alphafold.ebi.ac.uk/entry/E1BLP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021041", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021041", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "504848", "url": "https://www.ncbi.nlm.nih.gov/gene/504848", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504848", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504848", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HTRMMID", "url": "https://omabrowser.org/oma/group/HTRMMID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BLP0", "url": "https://www.orthodb.org/?gene=E1BLP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16830", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16830", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16830:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16830:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14603", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14603", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002688937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688937", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BLP0", "url": "https://www.uniprot.org/uniprotkb/E1BLP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLP0-1", "url": "https://www.uniprot.org/uniprotkb/E1BLP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSHQDFRSLQAKFQASQPETGDLPKKPPKPEFQKLLKKFPQPELGEHPKKPPQPEFTDLPKKPPKLEFSELSKKFLQPEATPLPRKPEVPEAPSQKPPQQPELSNTPRPPMEPKFSTPHKKPPQPEFCGLPRKPPQPQVSGLPKKPLPQPESSEIPPVPLLKPEFSEPHPHSSEPNFSTLPKKLPQPEFCELPRKPLQPQVGGLPKKPLLQPESSEVPPVPLLKPEFGEPHPHSSEPNFSTLPKKAPQPEFCELPRKPLQPQVSGLPKKPLLQPESSEVPPVPLSKPESGEPHPHSSQPDFSTFPRKIARPQLNDLPKKPLPPEFGDLTRTSSEPEVSVVPKKPRQCEFKVLSKKPPQPEPTSLSRTSSEPEFSVFPSKFLQPECRGPPRKLSQPEPGSLPRNLPRKPLLPGSFSESSLPSAVAGSNPRVPLSPGFGARQQRSGALARSAGSRLGLRPGHLPRRRPLPPASSLGPPPAKPPLPPGPRDIQSFRRAAAADTALPRTSSSAGLYLIPQDPDEVYDDVEPTDHSGPGPRSRDEALSAQQYPWRPPQNPELRKEKVPLQPPQVPPTDLKSLKQLRKAEKAEREFRKKFKFEGEIVVQTRMMIDPNAKTRRGGGKHLGIRRGEILEVIEFTSKEEMLCRDTKGKYGYVPRTALLPLETEVYDDVAAWDPLDSQPLP", "length": 682, "header": "tr|E1BLP0-1|E1BLP0_BOVIN Isoform 1 of PML-RARA-regulated adapter molecule 1 OS=Bos taurus OX=9913 GN=PRAM1 PE=4 SV=3 CANONICAL=E1BLP0-1" }, "isoforms": [ { "isoform_ac": "E1BLP0-1", "url": "https://www.uniprot.org/uniprotkb/E1BLP0/entry#E1BLP0-1", "sequence": { "sequence": "MGSHQDFRSLQAKFQASQPETGDLPKKPPKPEFQKLLKKFPQPELGEHPKKPPQPEFTDLPKKPPKLEFSELSKKFLQPEATPLPRKPEVPEAPSQKPPQQPELSNTPRPPMEPKFSTPHKKPPQPEFCGLPRKPPQPQVSGLPKKPLPQPESSEIPPVPLLKPEFSEPHPHSSEPNFSTLPKKLPQPEFCELPRKPLQPQVGGLPKKPLLQPESSEVPPVPLLKPEFGEPHPHSSEPNFSTLPKKAPQPEFCELPRKPLQPQVSGLPKKPLLQPESSEVPPVPLSKPESGEPHPHSSQPDFSTFPRKIARPQLNDLPKKPLPPEFGDLTRTSSEPEVSVVPKKPRQCEFKVLSKKPPQPEPTSLSRTSSEPEFSVFPSKFLQPECRGPPRKLSQPEPGSLPRNLPRKPLLPGSFSESSLPSAVAGSNPRVPLSPGFGARQQRSGALARSAGSRLGLRPGHLPRRRPLPPASSLGPPPAKPPLPPGPRDIQSFRRAAAADTALPRTSSSAGLYLIPQDPDEVYDDVEPTDHSGPGPRSRDEALSAQQYPWRPPQNPELRKEKVPLQPPQVPPTDLKSLKQLRKAEKAEREFRKKFKFEGEIVVQTRMMIDPNAKTRRGGGKHLGIRRGEILEVIEFTSKEEMLCRDTKGKYGYVPRTALLPLETEVYDDVAAWDPLDSQPLP", "length": 682, "header": "tr|E1BLP0-1|E1BLP0_BOVIN Isoform 1 of PML-RARA-regulated adapter molecule 1 OS=Bos taurus OX=9913 GN=PRAM1 PE=4 SV=3 CANONICAL=E1BLP0-1" }, "locus": { "chromosome": "7", "start_pos": 17107852, "end_pos": 17099947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045301.5", "url": "https://www.ensembl.org/id/ENSBTAT00000045301.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042700.4", "url": "https://www.ensembl.org/id/ENSBTAP00000042700.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:504848", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504848", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5PPH4-1", "protein_name": "Zinc finger protein 414", "gene_name": "Znf414", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEELSGPSSDTLATVESSSNEPDKEVASPDVAATATLSSVEEPGPNPTATPPVWDRGGPLQQVACPVPDSCQTSSTTRGVGTNEDLRLPRRRPPPGKQIPCSSPGCSLSFPSVRDLAQHLRTHCPPTQSLEGKLFRCSALSCTESFPSMQELVAHGKLHYKPNRYFKCENCLLRFRTHRSLFKHLHVCIDHGQNPAPPPPPALDKEPPVPERPPESDPSSSLGLPFPLLEPFTSAPTGPFLPYLNPAPFGLSPPRLRPFLAATPGPPTSSTAIWKKSQGATSSPRRPQGGSDAPSGACR", "length": 299 }, "evidence": [ { "id": "E1BLP0", "url": "https://omabrowser.org/oma/group/E1BLP0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6BCL1-1", "protein_name": "PML-RARA-regulated adapter molecule 1", "gene_name": "Pram1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSNQDFRNLQAKFQTSQPELGELFRKTPKPELNKVLKKFPQTELSEQPKKSSQSELSAVSLKPLQLQFADLPRKPPQPGVLKKSPQPEFPHLANKPVQAEFPRKPLHPEFTGLKKPSQAEFTDLKKPPQPQFASLPKKPPKPEFGELSKRPPQLETPQEPSAPPAQKLLKPEPNNPARPLGELKPKMFWHLEANEAPKRPLPSESSTFPKKPLQPEAVVGFSRKSQPQSESIEVSQTSPSKCGSRELDSHSPQPDISTFPKNNENFRKPSYPQATGCPKSPKQPMFYEFPQTPPRKPESCNPQSHSPLPDFNAFPKKHPQLQPSDLTRASSEPEVCKVPKKTQKPDPNVLSQKPSQPELGHLPRTSSDPEFNSLPRKFLQPQHGKFFQPEFPKGLPRKPKLPGSVSECSLPSASAGSSPQCPLSPGLIVPGIPRWRSEDFQVQRPPRRRPLPSASSLGHPPAKPALPPGPINIQSFRRAAATAAAVLKTGSSTGTHFQAQQPQHIAQNPDEIYELYDAVEATDDSSISPRGRDEMLSTQQATRWPQQEPELRKKATQPQQLPATDPKLLKQIRKAEKAEREFRKKFKFEGEIVIHTKMMIDPNAKTRRGGGKHLGIRRGEILEVIEFTSKDEMLCRDPKGKYGYVPRTALLPLETEVYDDVSFGDPLDMQPFPR", "length": 675 }, "evidence": [ { "id": "E1BLP0", "url": "https://omabrowser.org/oma/group/E1BLP0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96QH2-1", "protein_name": "PML-RARA-regulated adapter molecule 1", "gene_name": "PRAM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHHLPAAMESHQDFRSIKAKFQASQPEPSDLPKKPPKPEFGKLKKFSQPELSEHPKKAPLPEFGAVSLKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLELSDLSKKFPQLGATPFPRKPLQPEVGEAPLKASLPEPGAPARKPLQPDELSHPARPPSEPKSGAFPRKLWQPEAGEATPRSPQPELSTFPKKPAQPEFNVYPKKPPQPQVGGLPKKSVPQPEFSEAAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDFPKKPPQPELGDLTRTSSEPEVSVLPKRPRPAEFKALSKKPPQPELGGLPRTSSEPEFNSLPRKLLQPERRGPPRKFSQPEPSAVLKRHPQPEFFGDLPRKPPLPSSASESSLPAAVAGFSSRHPLSPGFGAAGTPRWRSGGLVHSGGARPGLRPSHPPRRRPLPPASSLGHPPAKPPLPPGPVDMQSFRRPSAASIDLRRTRSAAGLHFQDRQPEDIPQVPDEIYELYDDVEPRDDSSPSPKGRDEAPSVQQAARRPPQDPALRKEKDPQPQQLPPMDPKLLKQLRKAEKAEREFRKKFKFEGEIVVHTKMMIDPNAKTRRGGGKHLGIRRGEILEVIEFTSNEEMLCRDPKGKYGYVPRTALLPLETEVYDDVDFCDPLENQPLPLGR", "length": 670 }, "evidence": [ { "id": "E1BLP0", "url": "https://omabrowser.org/oma/group/E1BLP0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BLP0", "url": "https://www.uniprot.org/uniprotkb/E1BLP0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "E1BLP0", "url": "https://www.uniprot.org/uniprotkb/E1BLP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "E1BLP0", "url": "https://www.uniprot.org/uniprotkb/E1BLP0" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "E1BLP0", "url": "https://www.uniprot.org/uniprotkb/E1BLP0" } ], "pmid": "" }, { "name": "T 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"interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLP0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 682, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLP0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLP0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLP0" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 586, "end_pos": 664, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLQ9-1", "uniprot_ac": "E1BLQ9", "uniprot_id": "E1BLQ9_BOVIN", "mass": { "chemical_mass": 93242.0, "monoisotopic_mass": 93242.0 }, "refseq": { "ac": "XP_005214774", "name": "phosphatidate phosphatase LPIN3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214774" }, "gene_names": [ { "name": "LPIN3", "type": "recommended", "evidence": [ { "id": "E1BLQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ] }, { "name": "LPIN3", "type": "synonym", "evidence": [ { "id": "XP_005214774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214774" } ] } ], "protein_names": [ { "name": "phosphatidate phosphatase", "type": "recommended", "evidence": [ { "id": "E1BLQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.4", "type": "synonym", "evidence": [ { "id": "E1BLQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9/entry#names_and_taxonomy" } ] }, { "name": "phosphatidate phosphatase LPIN3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005214774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214774" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLQ9", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LPIN3", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9", "locus": { "chromosome": "13", "start_pos": 69990650, "end_pos": 69973201, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009165", "url": "https://www.ensembl.org/id/ENSBTAG00000009165" } ] } } ], "crossref": [ { "id": "E1BLQ9", "url": "https://alphafold.ebi.ac.uk/entry/E1BLQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009165", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009165", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "521637", "url": "https://www.ncbi.nlm.nih.gov/gene/521637", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031703", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031703", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12181:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12181:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16876", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16876", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1483191", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483191", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1483213", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4419969", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4419969", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-75109", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75109", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005214774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214774", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "27429", "url": "https://www.rhea-db.org/rhea/27429", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BLQ9", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLQ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNYMGQLAETVFGTVKGLYRGLNPATLSGGIDVLVVRQVDGSFRCSPFHVRFGKLGVLRSREKVVDIEINGEPVDLHMKLGDSGEAFFVQELESDEEDVPPRLCTSPIPWGGLAGFPSDSQLGTTSEPDASIAGMASSGRKKKRRRRKTKRKEGTVAADSSSEELEAGAESEPSLLEKPRPEPPGSIQPEGESPPEPKDIYPYSDGEWHPQASLSPGELTSPKSDSELELRTPEPSPLRAESHMQWAWGRLPKVGKAEWPESSVVADASSRTASPPQGAPSTPSTSVIGVDPPGLPTLQRGAGTDLLQPDTEAPALAGPPLSAPEREETKTQSSGDAGPRPPSKSWSWAALEDPAHTRKPEGVSQRKGSLKRSQHLGPSDIYLDDLPSLDSENAALYFPQSNSGLGAGKWSAPDSLKPLGDCNPEQEPEPIADTADAVALSLCGGLADSRDVSVEKFSQHLVSYEDLAQNPGLLDDPNLVVKINKQHYNWAVAAPMILSLQAFQKNLPKSTVDKLEKEKMPRKGGRWWFSWRRRDFPAKECSAQREKTAVREQRGEKTEALSSEDDTLDSPVILEAPSPPPSPPAHARAYKKSLRLSSSQIRRLNLQEGANDVVFSVTTQYQGTCRCRATIYLWKWDDKVVISDIDGTITKSDALGHILPQLGKDWTHQGITSLYHKIHLNGYKFLYCSARAIGMANLTKGYLQWVSERGCGLPKGPILLSPSSLFSALHREVIERKPEVFKIACLSDVQQLFLPQEQPFYAAFGNRPNDVTAYRQVGLPACRIFTVNPRGELSQELIKNHKSTYERLSEVVELLFPPVARGPSTDLAHPEYSNFCYWREPLAPVDLDALA", "length": 851, "header": "tr|E1BLQ9-1|E1BLQ9_BOVIN Isoform 1 of phosphatidate phosphatase OS=Bos taurus OX=9913 GN=LPIN3 PE=3 SV=3 CANONICAL=E1BLQ9-1" }, "isoforms": [ { "isoform_ac": "E1BLQ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9/entry#E1BLQ9-1", "sequence": { "sequence": 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CANONICAL=E1BLQ9-1" }, "locus": { "chromosome": "13", "start_pos": 69990123, "end_pos": 69977622, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012081.8", "url": "https://www.ensembl.org/id/ENSBTAT00000012081.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012081.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012081.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 282, "start_aa": "Thr", "end_pos": 282, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-1483191", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483191", "resource": "Reactome", "description": "Synthesis of PC" }, { "id": "R-BTA-1483213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483213", "resource": "Reactome", "description": "Synthesis of PE" }, { "id": "R-BTA-4419969", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4419969", "resource": "Reactome", "description": "Depolymerization of the Nuclear Lamina" }, { "id": "R-BTA-75109", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75109", "resource": "Reactome", "description": "Triglyceride biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ9", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ], "pmid": "" }, { "name": "phosphatidate phosphatase activity", "id": "GO:0008195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008195", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ9", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ9", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ9", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "fatty acid catabolic process", "id": "GO:0009062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009062", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ9", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ], "pmid": "" }, { "name": "cellular response to insulin stimulus", "id": "GO:0032869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032869", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ9", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ9", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ], "pmid": "" }, { "name": "triglyceride biosynthetic process", "id": "GO:0019432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019432", "evidence": [ { "database": "UniProtKB", "id": "E1BLQ9", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "27429", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BPE8-1", "A0A3Q1M9U2-1", "E1BLQ9-1", "A0AAA9STE8-1", "Q3SZE3-1", "Q2HJ61-1", "F1MH11-1", "F1MXQ6-1" ], "evidence": [ { "id": "27429", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27429" } ] }, { "id": "R-BTA-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BPE8-1", "A0A3Q1M9U2-1", "E1BLQ9-1" ], "evidence": [ { "id": "R-BTA-1483203", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483203" } ] }, { "id": "R-BTA-4419948", "name": "CTDNEP1:CNEP1R1 dephosphorylates LPIN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nuclear envelope, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1RMV9-1", "E1BPE8-1", "A0A3Q1M9U2-1", "E1BLQ9-1" ], "evidence": [ { "id": "R-BTA-4419948", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4419948" } ] }, { "id": "R-BTA-5195402", "name": "CDK1 phosphorylates LPIN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P48734-1", "E1BPE8-1", "A0A3Q1M9U2-1", "E1BLQ9-1" ], "evidence": [ { "id": "R-BTA-5195402", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5195402" } ] }, { "id": "R-BTA-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nuclear envelope, nucleoplasm", "input_participant_list": [ "R-ALL-5221122" ], "output_participant_list": [ "R-ALL-5221124" ], "enzyme_list": [ "E1BPE8-1", "A0A3Q1M9U2-1", "E1BLQ9-1" ], "evidence": [ { "id": "R-BTA-5221130", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5221130" } ] }, { "id": "R-BTA-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-76108" ], "output_participant_list": [], "enzyme_list": [ "E1BPE8-1", "A0A3Q1M9U2-1", "E1BLQ9-1" ], "evidence": [ { "id": "R-BTA-75899", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75899" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5221122", "participant_name": "1,2-diacyl-glycerol 3-phosphate [nuclear envelope]", "crossref": [ { "id": "58608", "database": "ChEBI", "url": "" }, { "id": "25202796", "database": "PubChem Compound", "url": "" }, { "id": "DIACYLGLYCEROL-PYROPHOSPHATE", "database": "AraCyc", "url": "" }, { "id": "C00416", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-5221124", "participant_name": "DAG [nuclear envelope]", "crossref": [ { "id": "17815", "database": "ChEBI", "url": "" }, { "id": "C00165", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-76108", "participant_name": "1,2-daG3P [cytosol]", "crossref": [ { "id": "58608", "database": "ChEBI", "url": "" }, { "id": "25202796", "database": "PubChem Compound", "url": "" }, { "id": "DIACYLGLYCEROL-PYROPHOSPHATE", "database": "AraCyc", "url": "" }, { "id": "C00416", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M9U2", "gene_name": "LPIN2", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0A3Q1M9U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9U2" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "A0A3Q1M9U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9U2" } ] } ] }, { "uniprot_ac": "A0AAA9STE8", "gene_name": "PLPP1", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] }, { "ec_number": "3.1.3.106", "activity": "a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] }, { "ec_number": "3.6.1.75", "activity": "a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] }, { "ec_number": "3.6.1.75", "activity": "", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] }, { "ec_number": "3.1.3.106", "activity": "", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] } ] }, { "uniprot_ac": "E1BLQ9", "gene_name": "LPIN3", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "E1BLQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "E1BLQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ9" } ] } ] }, { "uniprot_ac": "E1BPE8", "gene_name": "LPIN1", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "E1BPE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPE8" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "E1BPE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPE8" } ] } ] }, { "uniprot_ac": "F1MH11", "gene_name": "PLPP5", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "F1MH11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH11" } ] }, { "ec_number": "3.6.1.75", "activity": "a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H(+).", "evidence": [ { "id": "F1MH11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH11" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "F1MH11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH11" } ] }, { "ec_number": "3.6.1.75", "activity": "", "evidence": [ { "id": "F1MH11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH11" } ] } ] }, { "uniprot_ac": "F1MXQ6", "gene_name": "PLPP4", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "F1MXQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXQ6" } ] }, { "ec_number": "3.6.1.75", "activity": "a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H(+).", "evidence": [ { "id": "F1MXQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXQ6" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "F1MXQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXQ6" } ] }, { "ec_number": "3.6.1.75", "activity": "", "evidence": [ { "id": "F1MXQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXQ6" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "Q1RMV9", "gene_name": "CTDNEP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q1RMV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMV9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q1RMV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMV9" } ] } ] }, { "uniprot_ac": "Q2HJ61", "gene_name": "PLPP2", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q2HJ61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ61" } ] }, { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "Q2HJ61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ61" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "Q2HJ61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ61" } ] } ] }, { "uniprot_ac": "Q3SZE3", "gene_name": "PLPP3", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": 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"section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLR1-1", "uniprot_ac": "E1BLR1", "uniprot_id": "E1BLR1_BOVIN", "mass": { "chemical_mass": 57382.0, "monoisotopic_mass": 57382.0 }, "refseq": { "ac": "NP_001179609", "name": "spermatogenesis-associated protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179609" }, "gene_names": [ { "name": "SPATA2", "type": "recommended", "evidence": [ { "id": "E1BLR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ] }, { "name": "SPATA2", "type": "synonym", "evidence": [ { "id": "NP_001179609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179609" } ] } ], "protein_names": [ { "name": "Spermatogenesis-associated protein 2", "type": "recommended", "evidence": [ { "id": "E1BLR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLR1/entry#names_and_taxonomy" } ] }, { "name": "spermatogenesis-associated protein 2", "type": "synonym", "evidence": [ { "id": "NP_001179609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179609" } ] } ], "function": [ { "annotation": "Bridging factor that mediates the recruitment of CYLD to the LUBAC complex, thereby regulating TNF-induced necroptosis. Acts as a direct binding intermediate that bridges RNF31/HOIP, the catalytic subunit of the LUBAC complex, and the deubiquitinase (CYLD), thereby recruiting CYLD to the TNF-R1 signaling complex (TNF-RSC). Required to activate the 'Met-1'- (linear) and 'Lys-63'-linked deubiquitinase activities of CYLD. Controls the kinase activity of RIPK1 and TNF-induced necroptosis by promoting 'Met-1'-linked deubiquitination of RIPK1 by CYLD.", "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1#function" }, { "database": "UniProtKB", "id": "ARBA00094298", "url": "https://www.uniprot.org/uniprotkb/ARBA00094298#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPATA2", "url": "https://www.uniprot.org/uniprotkb/E1BLR1", "locus": { "chromosome": "13", "start_pos": 77982558, "end_pos": 77993066, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018063", "url": "https://www.ensembl.org/id/ENSBTAG00000018063" } ] } } ], "crossref": [ { "id": "E1BLR1", "url": "https://alphafold.ebi.ac.uk/entry/E1BLR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018063", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018063", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19757", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19757", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "529745", "url": "https://www.ncbi.nlm.nih.gov/gene/529745", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR048839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:529745", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529745", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NKQRPIN", "url": "https://omabrowser.org/oma/group/NKQRPIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BLR1", "url": "https://www.orthodb.org/?gene=E1BLR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15326", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15326", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15326:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15326:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5357786", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357786", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357905", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5357956", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179609", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179609", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLR1-1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKPSSMDAKYKDDLFRKYVQFHESQGDATPSSDESLRAAASTLLSLHKVDPCYRFRLIQFYEVVESSLRSLRSSSLRALRCAFSVLETMGINLFLCPWKKEFRSIKTYTGPFVYYVKSTLLEEDIRAILSYMGYMPELGTAYRLKELVETLQVKMVSFELFLAKVECEQMLEIHSQVKDKGYTELDVVSERRGSVEDARGCAEALRRRAEAREPLSASMARVVLQKSASERAAKDYYKPRVTKPSRSVDTYDSYWESRKPPLKTSLSLRKEPAAAEPGDELKDEIIRPPPSLLTVAGSPHGGADDLPAPAPSNGLGLLRGPYLPGSDDVDLYTDAEPRAAYRRQDALRPDVWLLRNDAHPGYHKRSTPAKESALSKCQNCGLSCSAALCQRCDSLLACSPAAKPSAFPGKASGHDSLAHGAALREKYAGQTQGLERPPHLHSKSKPPSAVAATSRCGFCNRPGAANTCTQCSKVSCDACLSAYHYDPCCKKSELHKFMPNNQLNYKSTQFSHLVYR", "length": 517, "header": "tr|E1BLR1-1|E1BLR1_BOVIN Isoform 1 of Spermatogenesis-associated protein 2 OS=Bos taurus OX=9913 GN=SPATA2 PE=3 SV=1 CANONICAL=E1BLR1-1" }, "isoforms": [ { "isoform_ac": "E1BLR1-1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1/entry#E1BLR1-1", "sequence": { "sequence": "MGKPSSMDAKYKDDLFRKYVQFHESQGDATPSSDESLRAAASTLLSLHKVDPCYRFRLIQFYEVVESSLRSLRSSSLRALRCAFSVLETMGINLFLCPWKKEFRSIKTYTGPFVYYVKSTLLEEDIRAILSYMGYMPELGTAYRLKELVETLQVKMVSFELFLAKVECEQMLEIHSQVKDKGYTELDVVSERRGSVEDARGCAEALRRRAEAREPLSASMARVVLQKSASERAAKDYYKPRVTKPSRSVDTYDSYWESRKPPLKTSLSLRKEPAAAEPGDELKDEIIRPPPSLLTVAGSPHGGADDLPAPAPSNGLGLLRGPYLPGSDDVDLYTDAEPRAAYRRQDALRPDVWLLRNDAHPGYHKRSTPAKESALSKCQNCGLSCSAALCQRCDSLLACSPAAKPSAFPGKASGHDSLAHGAALREKYAGQTQGLERPPHLHSKSKPPSAVAATSRCGFCNRPGAANTCTQCSKVSCDACLSAYHYDPCCKKSELHKFMPNNQLNYKSTQFSHLVYR", "length": 517, "header": "tr|E1BLR1-1|E1BLR1_BOVIN Isoform 1 of Spermatogenesis-associated protein 2 OS=Bos taurus OX=9913 GN=SPATA2 PE=3 SV=1 CANONICAL=E1BLR1-1" }, "locus": { "chromosome": "13", "start_pos": 77987100, "end_pos": 77984714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024049.5", "url": "https://www.ensembl.org/id/ENSBTAT00000024049.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024049.4", "url": "https://www.ensembl.org/id/ENSBTAP00000024049.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 30, "start_aa": "Thr", "end_pos": 30, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr30", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:529745", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529745", "resource": "KEGG Pathway" }, { "id": "R-BTA-5357786", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357786", "resource": "Reactome", "description": "TNFR1-induced proapoptotic signaling" }, { "id": "R-BTA-5357905", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357905", "resource": "Reactome", "description": "Regulation of TNFR1 signaling" }, { "id": "R-BTA-5357956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357956", "resource": "Reactome", "description": "TNFR1-induced NF-kappa-B signaling pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZI91-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKPSSMDTKYKDDLFRKYVQFHEGKVDTTPSKQRPGSDEYLRVAASTLLSLHKVDPFYRFRLIQFYEVVESSLRSLSSSSLRALHCAFSVLETVGINLFLYPWKKEFRSIKTYTGPFVYYVKSTLLEEDIRAILNYMGYVPELGTAYKLKELVETLQVKMVTFELFLAKVECEQMLEIHSQVKDKGYSELDVVSERKSSTEDVRGCSDALRRRAEGREHLTASMARVVLQKSASERAAKDYYKPRVTKPSRSVDAYDSYWESRKPPLKASLSLRKEPAAADVGDDLKDEIMRPSPSLLTMSTSPHGSPDDLAAPSPNNGLGSLRGSYLSAQDDVDLYTDSEPRAAYRRQDALRPDVWVVRNDAHPVYHKRSPPAKESSLSKCQNCGLSCSSSLCQRCDSLLACSPASKPSAFPSKASAHDSLAHGSSLREKYAGQTQGLDRPPHLHSKSKPSASATSRCGFCNRPGATNTCTQCSKVSCDTCLSAYHYDPCCKKSELHKFMPNNQLNYKSTQFSHLVYR", "length": 520 }, "evidence": [ { "id": "E1BLR1", "url": "https://omabrowser.org/oma/group/E1BLR1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QCY8-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "spata2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDAKLREDLFRRYVASLENRLEEGAAEGGGDRQGAKTEEALISTATALLGSYQADPGQRFRMLRFYDVVENSLRTQRGTSLRTVGTAFATLETICTNLLLFPWKKEYRCIKTFTGPYVYQLQSVLCDSDLRSLLRSMGYSREQELQYNVRDHPGGASHLRQLAFELLLAQAECRLLGEVVSMSRGFASELEAVELRRNTREDAAGCADALRRRDSLTGDLSRLSVRPLDIDRAHLRRSGRPSKSVDVTDSAGHWHQASKPVLKASLSLRKEPLFVDTEEDMKDEIIRPSPSLYPVAAPPSYSPVADFFPIQSPPSEPYSYHLSSLDEVDLYTERGLGGHQTPSRPPSREPRDSWVLKGHMMKCQGCGMGCPSLSSCQRCDMILCSSCHAVDPAPCCGFQDYTKTSRPLDGYMPIKEKLSVYSSAHSHTHPHPHPLPHAQSHSLLLDKAVMSSKLFPSKPVGSGPSPVGSLVSSGSSSSGGERLSVGGSRCGFCNKPGASHTCVNCSKVSCDTCMSLYASDLCTRKNPHHNFVPNHQLNFKSSTISHLVYR", "length": 550 }, "evidence": [ { "id": "E1BLR1", "url": "https://omabrowser.org/oma/group/E1BLR1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HET4-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "Spata2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDTKYKDDLFRKYVQFHESKVDTTPSKQQPGDEYLRVAAATLLSLHKVDPLQRFRLIRFYEVVESSLRSLSSASLSALHCAFSMLETVAVNLFLFPWKKEFRSIKTYTGPFVYYVKSTLLEEDIRAILRFMGYEPELGTAYRLKELVESRQVKMVSFELFLAKVECEQMLGIHSKVKDKGYSELDVVSERKSSTEDAHGCSDALRRRAESREHLTTSMARVALQKSASERAAKDYYKPRVTKPSRSVDAYDSYWEGRKLPSKASLSLRKEPLAMDVGDDLKDEIIRPSPSLLTMSSSPHGSPDDPPSISPINGLGLLRSTYLSTQDDVDLYTDSEPRATYRRQDALRPDVWLVKNDAHPIYHKRSPPTKESALSKCQNCGLSCSSSLCQRCDSLLGCPSASKPSAFPSKASAHDSLVHGAPMREKYVGQTQGLDRLPPVHSKPKPSTTATSRCGFCNRVGATNTCTQCSKVSCDACLGAYHYDPCCRKSELHKFMPNNQLNYKSTQFSHLVYR", "length": 513 }, "evidence": [ { "id": "E1BLR1", "url": "https://omabrowser.org/oma/group/E1BLR1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q66HP6-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "Spata2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTKYKDDLFRKYVQFHEGKVDTTPGKQSGSDEYLRVAAATLLSLHKVDPLYRFRLIQFYEVVESSLRSLSSSSLSALHCAFSMLETMAINLFLFPWKKEFRSIKTYTGPFVYYVKSTLLEKDIRAILKFMGYEPELGTAYKLKELVESLQVKMVSFELFLAKVECEQMLGIHSQVKDKGYSELDVVTERKSSTEDARGCSDALRRRAESREHLTTSMARVALQKSASERAAKDYYKPRVTKPSRSVDAYDSYWESRKPPSKASLSLRKEPLAMDVGEDLKDEIIRPSPSLLTMSSSPHGSPDDLPSISPINGLGLLRSTYFPTQDDVDLYTDSEPRATYRRQDALRSDIWLVKNDAHSIYHKRSPPTKESALSKCQNCGLSCSSSLCQRCDSVCPSASKPSGFPSKASAHDSLVHGAPMREKYVGQTQGLDRLATVHSKPKPSTTATSRCGFCNRAGATNTCTQCSKVSCDPCLGAYHYDPCCRKSELHKFMPNNQLNYKSTQFSHPVYR", "length": 511 }, "evidence": [ { "id": "E1BLR1", "url": "https://omabrowser.org/oma/group/E1BLR1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K004-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "Spata2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTKYKDDLFRKYVQFHEGKVDTTPGNQQPGSDEYLRVAAATLLSLHKVDPLYRFRLIQFYEVVESSLRSLSSSSLSALHCAFSMLETMAINLFLFPWKKEFRSIKTYTGPFVYYVKSTLLEKDIRAILRFMGYEPELGTVYKLKELVESLQVKMVSFELFLAKVECEQMLGIHSQVKDKGYSELDVVAERKGSTEDARGCSDALRRRAESREHLTTSMARVALQKSASERAAKDYYKPRVTKPSRSVDAYDSYWESRKPPSKASLSLRKEPLAMDVGEDLKDEIIRPSPSLLAMSSSPHGSPDDLSSISSINGLGLLRSTYFSTQDDVDLYTDSEPRATYRRQDALRPDVWLVKNDTHPIYHKRSPPTKESALSKCQNCGLSCSSSLCQRCDSVLVCPSASKPSAFPSKASVHDSLAHGAPMREKYVGHQTQGLDRLAPVHSKPKPSTTATSRCGFCNRAGATNTCTQCSKVSCDACLGAYHYDPCCRKSELHKFLPNSQLNYKSAPFSQLVYR", "length": 515 }, "evidence": [ { "id": "E1BLR1", "url": "https://omabrowser.org/oma/group/E1BLR1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKPSSMDTKFKDDLFRKYVQFHESKVDTTTSRQRPGSDECLRVAASTLLSLHKVDPFYRFRLIQFYEVVESSLRSLSSSSLRALHGAFSMLETVGINLFLYPWKKEFRSIKTYTGPFVYYVKSTLLEEDIRAILSCMGYTPELGTAYKLRELVETLQVKMVSFELFLAKVECEQMLEIHSQVKDKGYSELDIVSERKSSAEDVRGCSDALRRRAEGREHLTASMSRVALQKSASERAAKDYYKPRVTKPSRSVDAYDSYWESRKPPLKASLSLRKEPVATDVGDDLKDEIIRPSPSLLTMASSPHGSPDVLPPASPSNGPALLRGTYFSTQDDVDLYTDSEPRATYRRQDALRPDVWLLRNDAHSLYHKRSPPAKESALSKCQSCGLSCSSSLCQRCDSLLTCPPASKPSAFPSKASTHDSLAHGASLREKYPGQTQGLDRLPHLHSKSKPSTTPTSRCGFCNRPGATNTCTQCSKVSCDACLSAYHYDPCYKKSELHKFMPNNQLNYKSTQLSHLVYR", "length": 520 }, "evidence": [ { "id": "E1BLR1", "url": "https://omabrowser.org/oma/group/E1BLR1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ], "pmid": "" }, { "name": "regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:0010803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010803", "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ], "pmid": "" }, { "name": "regulation of necroptotic process", "id": "GO:0060544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060544", "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ], "pmid": "" }, { "name": "protein linear deubiquitination", "id": "GO:1990108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990108", "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ], "pmid": "" }, { "name": "ubiquitin-specific protease binding", "id": "GO:1990381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990381", "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ], "pmid": "" }, { "name": "signaling receptor complex adaptor activity", "id": "GO:0030159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030159", "evidence": [ { "database": "UniProtKB", "id": "E1BLR1", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLR1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 517, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLR1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLR1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLR1" }, { "id": "PF21388", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21388" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Spermatogenesis-associated protein 2 PUB-like", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 202, "start_aa": "Leu", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 30 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BLT9-1", "uniprot_ac": "E1BLT9", "uniprot_id": "E1BLT9_BOVIN", "mass": { "chemical_mass": 97686.0, "monoisotopic_mass": 97686.0 }, "refseq": { "ac": "XP_024840907", "name": "armadillo repeat-containing protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840907" }, "gene_names": [ { "name": "ARMC5", "type": "recommended", "evidence": [ { "id": "E1BLT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLT9" } ] }, { "name": "ARMC5", "type": "synonym", "evidence": [ { "id": "XP_024840907", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840907" } ] } ], "protein_names": [ { "name": "Armadillo repeat containing 5", "type": "synonym", "evidence": [ { "id": "E1BLT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLT9/entry#names_and_taxonomy" } ] }, { "name": "armadillo repeat-containing protein 5", "type": "synonym", "evidence": [ { "id": "XP_024840907", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840907" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLT9", "url": "https://www.uniprot.org/uniprotkb/E1BLT9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARMC5", "url": "https://www.uniprot.org/uniprotkb/E1BLT9", "locus": { "chromosome": "25", "start_pos": 27501199, "end_pos": 27493118, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002374", "url": "https://www.ensembl.org/id/ENSBTAG00000002374" } ] } } ], "crossref": [ { "id": "E1BLT9", "url": "https://alphafold.ebi.ac.uk/entry/E1BLT9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002374", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002374", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515835", "url": "https://www.ncbi.nlm.nih.gov/gene/515835", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515835", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515835", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NCCTEGG", "url": "https://omabrowser.org/oma/group/NCCTEGG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BLT9", "url": "https://www.orthodb.org/?gene=E1BLT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23312", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23312", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23312:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23312:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24768", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24768", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024840907", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840907", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BLT9", "url": "https://www.uniprot.org/uniprotkb/E1BLT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLT9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAKSTPTDSLSFCLAQLTAAAGEGLGGRKDTATSETPLGRALLALRTRHVKAAGGIERFRARGGLRPLLALLRRAAAAGPAPSQAGAGSAPSSVESAASSGPAPSPGSAPSAASPATPSPPARLRKTLDLALSILANCCTEGACRAEVRRLGGILPLVTILQCVKTDSIQNRTARALGNLAMEPESCGDIHCAGAVPLLVESLTACQDSQCRQSVVRALRNLADSPQHRLALAQQGAVRPLAELLAAAPDPALTLALVRALLELSRGCSRACAEQLSLGGGLGPLVGLASHPKRAVREATILILANLCAQGLVRPALGNAGGVEVLLGELRRRRGLNGASPASQQPLVRAVCLLCREAINRARLRDAGGLELLMGLLRDPRASAWHPRVVAALVGFLYDTGALGRLQALGLVPLLAGQLCGEAGDEEEEGREAASWDFPEERTPERAEAGSFRSLQSWLISEGYAAGPGDISPDWSPECCPPPPEPADLTSPTSLRTPRALRPPGRSPTASAAEEPWGREGPALLLLSRFSQAPDPSGALVTGPALCGLLAYVTGAPGPPSPRALRILARLTCNPACLEAFVRSYGAALLRAWLVLGVAPDDWPALRTRQARRSQHQHRELGEMLLQNLTVQAESPFGVGALTHLLLSGSPEDRVACALTLPFICRKPSLWRRLLLDQGGLRLLLSALTRPAPHPLFLFFAADSLSCLQGLVSPTGSPAILPAIPLDLDPPSPCLYEPLLGPAPMPAPDLHFLLDSGLRLPAQRAASATASPFFRALLAGSFAEAQMDLVPLRGLSPSAAWPILHHLHGCRGCGAALGPVPPPGQPLLGSEAEEALEAAGRFLLPGLEEELEEAVGRIHLGPQGGPESVGEVFRLGRPRLAAHCARWTLGPGQCPRKRALALVGLVEAAGEEAGPLTEALLAVVMGVESGGKGPSLDC", "length": 940, "header": "tr|E1BLT9-1|E1BLT9_BOVIN Isoform 1 of Armadillo repeat containing 5 OS=Bos taurus OX=9913 GN=ARMC5 PE=4 SV=3 CANONICAL=E1BLT9-1" }, "isoforms": [ { "isoform_ac": "E1BLT9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLT9/entry#E1BLT9-1", "sequence": { "sequence": "MAAAKSTPTDSLSFCLAQLTAAAGEGLGGRKDTATSETPLGRALLALRTRHVKAAGGIERFRARGGLRPLLALLRRAAAAGPAPSQAGAGSAPSSVESAASSGPAPSPGSAPSAASPATPSPPARLRKTLDLALSILANCCTEGACRAEVRRLGGILPLVTILQCVKTDSIQNRTARALGNLAMEPESCGDIHCAGAVPLLVESLTACQDSQCRQSVVRALRNLADSPQHRLALAQQGAVRPLAELLAAAPDPALTLALVRALLELSRGCSRACAEQLSLGGGLGPLVGLASHPKRAVREATILILANLCAQGLVRPALGNAGGVEVLLGELRRRRGLNGASPASQQPLVRAVCLLCREAINRARLRDAGGLELLMGLLRDPRASAWHPRVVAALVGFLYDTGALGRLQALGLVPLLAGQLCGEAGDEEEEGREAASWDFPEERTPERAEAGSFRSLQSWLISEGYAAGPGDISPDWSPECCPPPPEPADLTSPTSLRTPRALRPPGRSPTASAAEEPWGREGPALLLLSRFSQAPDPSGALVTGPALCGLLAYVTGAPGPPSPRALRILARLTCNPACLEAFVRSYGAALLRAWLVLGVAPDDWPALRTRQARRSQHQHRELGEMLLQNLTVQAESPFGVGALTHLLLSGSPEDRVACALTLPFICRKPSLWRRLLLDQGGLRLLLSALTRPAPHPLFLFFAADSLSCLQGLVSPTGSPAILPAIPLDLDPPSPCLYEPLLGPAPMPAPDLHFLLDSGLRLPAQRAASATASPFFRALLAGSFAEAQMDLVPLRGLSPSAAWPILHHLHGCRGCGAALGPVPPPGQPLLGSEAEEALEAAGRFLLPGLEEELEEAVGRIHLGPQGGPESVGEVFRLGRPRLAAHCARWTLGPGQCPRKRALALVGLVEAAGEEAGPLTEALLAVVMGVESGGKGPSLDC", "length": 940, "header": "tr|E1BLT9-1|E1BLT9_BOVIN Isoform 1 of Armadillo repeat containing 5 OS=Bos taurus OX=9913 GN=ARMC5 PE=4 SV=3 CANONICAL=E1BLT9-1" }, "locus": { "chromosome": "25", "start_pos": 27500593, "end_pos": 27493317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003076.8", "url": "https://www.ensembl.org/id/ENSBTAT00000003076.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003076.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003076.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 119, "start_aa": "Thr", "end_pos": 119, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr119", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:515835", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515835", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5EBP3-1", "protein_name": "Armadillo repeat-containing protein 5", "gene_name": "Armc5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAARPALTDSLSFCLAQLTAAAGEGPGGGKDPATNETPLGRALLALRTRHIKAAEGIERFRARGGLRPLLALLRRTAAAGPAPSQAASGSAPSSVASAGSTPGHAPAAESLLTPSLPMRLRKTLDLALSILANCCTEGACRAEVRRLGGILPLVTILQCVKTDSIQNRTARALGNLAMEPESCRDIHSAGAVPFLVESLTACQDSQCLQSIVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDPALTAALVRALLELSRGCSRACAEQLSLGGALGPLVSLASHPKRAIREAAILILANLCAQGLVRPALGNAGGVEVLLGELRRRRSPGGSSSATQQPLVRAVCLLCREAINRARLRDAGGLELLMGLLQDPGASAWHPRVVAALVGFLYDTGALGKLQALGLVPLLARQLCGEAGEEEEEGIEAASWDFPEERTSGQAEGGSFRSLRLWLISEGYAAGPGDISPDWSPERCPMPEPSESVSPTPGQTSMSTPRTLRKPGRIPAATPEEPWGQEGPALLLLSRFSQAPDPSGALVTGPALCGLLAYVTGAPGPPNPRALRILARLTCNPACLEAFVRTYGAALLRAWLVLGVSPDDWPVPHARPVHRSQHRELGEMLLQNLTVQAESPFGVGALTHLLLSGSPEDRVACALTLPFICRKPTLWRRLLLDQGGLRLLLTALTQPAPHPLFLFFAADSLSCLQGLVSPTASPVPLPALPLELDSPPPCLYEPLLGPAPAPAPDLHFVLDSGLQLPAQRAASAAASPFFRALLSGSFAEAQMDLVPLRGLSPGAAWPVLHHLHGCRGCGAALGPVPPPGQPLLGSKAEEALEAAGRFLLPALEEELEEAVGRIHLSPRGGPESVGEVFRLGRPRLAAHCARWTLEPGQCPRKRALALTGLVEAAGEEAGPLTEALLAVVMGIES", "length": 926 }, "evidence": [ { "id": "E1BLT9", "url": "https://omabrowser.org/oma/group/E1BLT9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5PQP9-1", "protein_name": "Armadillo repeat-containing protein 5", "gene_name": "Armc5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARPALTDSLSFCLAQLTAAAGEGPGGGKDPATNETALGRVLLALRTRHIKAAEGIERFRARGGLRPLVALLRRTAAAGPAPSQAASGSAPPSVASAGSSPGPAPAAESPLTLSAPMRLRKTLDLALSILANCCTEGACRSEVRRIGGILPLVTILQCVRIDSIQNRTARALGNLAMEPESCGDIHSAGAVPFLVESLTACQDSQCLQSIVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDPALTSALVRALLELSRGCSRACAEQLSLGGGLGPLVSLASHPKRAIREAAILILANLCAQGLVRPALGNAGGVEVLLGELRRRRGPSGSSSASQQPLVRAVCLLCREAINRARLRDAGGLELLMGLLQDPGASAWHPRVVAALVGFLYDTGALGKLQALGLVPLLARQLCGEAGEEEEEGVEAASWDFPEERTSGQPEGGSFRSLRLWLISEGYAAGPGDISPDWSPERCPMPEPSESVSPTPGQTSMSTPRTLRKLGRVPAATTEEPWGQEGPALLLLSRFSQAPDPSGALVTGPALCGLLAYVTGAPGPPNPRALRILARLTCNPACLEAFVRSYGAALLRAWLVLGVSPDDWPVPHARPVHRSQHRELGEMLLQNLTVQAESPFGVGALTHLLLSGSPEDRVACALTVPFICRKPTLWRRLLLDQGGLRLLLTALTQPAPHPLFLFFAADSLSCLQGLVSPSASPVPLPDLPLELDSPSPCLYKPLLGPAPAPAPDLHFVLDSGLQLPAQRAASAAASPFFRALLSGSFAEAQMNLVPLRGLSPSAAWPVLHHLHGCRGCGAALGPIPPPGQPLLGSKAEEALEAAGRFLLPALEEELEEAVGRIHLSPQGGPESVGEVFRLGRPRLAAHCARWTLEPGQCPRKRALALTGLVEAAGEEAGPLTEALLAVVMGVES", "length": 926 }, "evidence": [ { "id": "E1BLT9", "url": "https://omabrowser.org/oma/group/E1BLT9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96C12-1", "protein_name": "Armadillo repeat-containing protein 5", "gene_name": "ARMC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MAALQEKKSCGQRMEEFRRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGIFALCIYVLMCTIDPYTPDYQDQLKSPGVTLRPDTYGDKGLDISYNVSDNRTWTGLTQALRHFLAGYSPAAQEDNINCTSERYFFQERFLAPNHTKFSCKFTADMLQNCSGQPDPTFGFAEGKPCFIIKMNRIVKFLPGNSTAPRVDCAFLDQHRDAPALQVEYFPPNGSYSLHYFPYYGKKAQPHYSNPLVAAKLLNVPKNKEVVVVCKILAEHVTFDNPHDPYEGKVEFKLTIQK", "length": 290, "header": "tr|E1BLX8-1|E1BLX8_BOVIN Isoform 1 of Sodium/potassium-transporting ATPase subunit beta OS=Bos taurus OX=9913 GN=ATP4B PE=3 SV=1 CANONICAL=E1BLX8-1" }, "isoforms": [ { "isoform_ac": "E1BLX8-1", "url": "https://www.uniprot.org/uniprotkb/E1BLX8/entry#E1BLX8-1", "sequence": { "sequence": "MAALQEKKSCGQRMEEFRRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGIFALCIYVLMCTIDPYTPDYQDQLKSPGVTLRPDTYGDKGLDISYNVSDNRTWTGLTQALRHFLAGYSPAAQEDNINCTSERYFFQERFLAPNHTKFSCKFTADMLQNCSGQPDPTFGFAEGKPCFIIKMNRIVKFLPGNSTAPRVDCAFLDQHRDAPALQVEYFPPNGSYSLHYFPYYGKKAQPHYSNPLVAAKLLNVPKNKEVVVVCKILAEHVTFDNPHDPYEGKVEFKLTIQK", "length": 290, "header": "tr|E1BLX8-1|E1BLX8_BOVIN Isoform 1 of Sodium/potassium-transporting ATPase subunit beta OS=Bos taurus OX=9913 GN=ATP4B PE=3 SV=1 CANONICAL=E1BLX8-1" }, "locus": { "chromosome": "12", "start_pos": 86746800, "end_pos": 86742343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026587.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026587.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026587.4", "url": "https://www.ensembl.org/id/ENSBTAP00000026587.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614308", "resource": "KEGG Pathway" }, { "id": "R-BTA-936837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I7Z2-1", "protein_name": "Sodium/potassium-transporting ATPase subunit beta", "gene_name": "Atp4b", 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"MAALQEKKSCSQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMSGIFALCIYVLMRTIDPYTPDYQDQLKSPGVTLRPDVYGEKGLDISYNVSDSTTWAGLAHTLHRFLAGYSPAAQEGSINCTSEKYFFQESFLAPNHTKFSCKFTADMLQNCSGRPDPTFGFAEGKPCFIIKMNRIVKFLPGNSTAPRVDCAFLDQPRDGPPLQVEYFPANGTYSLHYFPYYGKKAQPHYSNPLVAAKLLNVPRNRDVVIVCKILAEHVSFDNPHDPYEGKVEFKLKIQK", "length": 290 }, "evidence": [ { "id": "E1BLX8", "url": "https://omabrowser.org/oma/group/E1BLX8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P18598-1", "protein_name": "Potassium-transporting ATPase subunit beta", "gene_name": "Atp4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQEKKSCSQRMAEFRQYCWNPDTGQMLGRTPARWVWISLYYAAFYVVMTGLFALCIYVLMQTIDPYTPDYQDQLKSPGVTLRPDVYGERGLQISYNISENSSWAGLTHTLHSFLAGYTPASQQDSINCSSEKYFFQETFSAPNHTKFSCKFTADMLQNCSGLVDPSFGFEEGKPCFIIKMNRIVKFLPSNNTAPRVDCTFQDDPQKPRKDIEPLQVQYYPPNGTFSLHYFPYYGKKAQPHYSNPLVAAKFLNVPKNTQVLIVCKIMADHVTFDNPHDPYEGKVEFKLTIQK", "length": 294 }, "evidence": [ { "id": 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"ENSBTAT00000049093.3", "url": "https://www.ensembl.org/id/ENSBTAT00000049093.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052821.1", "url": "https://www.ensembl.org/id/ENSBTAP00000052821.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "E1BLY1", "url": "https://omabrowser.org/oma/group/E1BLY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "E1BLY1", "url": "https://www.uniprot.org/uniprotkb/E1BLY1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "E1BLY1", "url": "https://www.uniprot.org/uniprotkb/E1BLY1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "E1BLY1", "url": "https://www.uniprot.org/uniprotkb/E1BLY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLY1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 130, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLY1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLY1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BM01", "url": "https://www.uniprot.org/uniprotkb/E1BM01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM01-1", "url": "https://www.uniprot.org/uniprotkb/E1BM01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSSRPSGLYLLEGCVCDRAPSPKPTLSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEWVAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEVEIERLKAEIASLLKDNERIQSTQTVTPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRKRNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLHQIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLLKHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELSRIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLGSLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSGQDVDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENSKVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNTFLHSYRVFTTAVVVLDKLITIYRKPISAIPARWAGSLELLFASGQNNKLLYGDPPKSPRATRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCSSNGYTSMYSAMSPFGKATLDTSKLYVSSSFANKIPDEGDTATEKSEEPSALSKQSSEVSMREESDNDQNQSDDGDTETSPTKSPTTPKSVKSKNSSEFPLFSYNNGVVMTSCRELDSNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETNDELKCKVISFLEEVMHDPELLTQERKAAANIIRTLTQDDPGDNQITLEEITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIVRNEDINARVSTIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKLPT", 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"MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSSRPSGLYLLEGCVCDRAPSPKPTLSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEWVAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEVEIERLKAEIASLLKDNERIQSTQTVTPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRKRNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLHQIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLLKHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELSRIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLGSLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSGQDVDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENSKVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNTFLHSYRVFTTAVVVLDKLITIYRKPISAIPARWAGSLELLFASGQNNKLLYGDPPKSPRATRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCSSNGYTSMYSAMSPFGKATLDTSKLYVSSSFANKIPDEGDTATEKSEEPSALSKQSSEVSMREESDNDQNQSDDGDTETSPTKSPTTPKSVKSKNSSEFPLFSYNNGVVMTSCRELDSNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETNDELKCKVISFLEEVMHDPELLTQERKAAANIIRTLTQDDPGDNQITLEEITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIVRNEDINARVSTIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKLPT", "length": 1260, "header": "tr|E1BM01-1|E1BM01_BOVIN Isoform 1 of Ras protein specific guanine nucleotide releasing factor 1 OS=Bos taurus OX=9913 GN=RASGRF1 PE=4 SV=3 CANONICAL=E1BM01-1" }, "locus": { "chromosome": "21", "start_pos": 25341094, "end_pos": 25240518, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026564.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026564.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026564.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026564.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BM01", "url": "https://www.uniprot.org/uniprotkb/E1BM01" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BM01", "url": "https://www.uniprot.org/uniprotkb/E1BM01" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "E1BM01", "url": "https://www.uniprot.org/uniprotkb/E1BM01" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "E1BM01", "url": "https://www.uniprot.org/uniprotkb/E1BM01" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": 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reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "E1BM01", "url": "https://www.uniprot.org/uniprotkb/E1BM01" } ], "pmid": "" }, { "name": "regulation of Ras protein signal transduction", "id": "GO:0046578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046578", "evidence": [ { "database": "UniProtKB", "id": "E1BM01", "url": "https://www.uniprot.org/uniprotkb/E1BM01" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E1BM01", "url": "https://www.uniprot.org/uniprotkb/E1BM01" } ], "pmid": "" }, { "name": "glutamate receptor binding", "id": "GO:0035254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035254", "evidence": [ { "database": "UniProtKB", "id": "E1BM01", "url": "https://www.uniprot.org/uniprotkb/E1BM01" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1023, "end_pos": 1025, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1124, "end_pos": 1126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1201, "end_pos": 1203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 834, "end_pos": 836, "annotation": "n_glycosylation_sequon" }, { "start_pos": 859, "end_pos": 861, "annotation": "n_glycosylation_sequon" }, { "start_pos": 883, "end_pos": 885, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM01-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1260, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM01-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM01" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM01" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 240, "end_pos": 426, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM01" }, { "id": "PS50212", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50212" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-terminal Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 631, "end_pos": 749, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM01" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 129, "start_aa": "Asp", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM01" }, { "id": "PS50009", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50009" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 1025, "end_pos": 1257, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1023, "end_pos": 1025 }, { "start_pos": 1124, "end_pos": 1126 }, { "start_pos": 1193, "end_pos": 1195 }, { "start_pos": 1201, "end_pos": 1203 }, { "start_pos": 834, "end_pos": 836 }, { "start_pos": 859, "end_pos": 861 }, { "start_pos": 883, "end_pos": 885 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM12-1", "uniprot_ac": "E1BM12", "uniprot_id": "E1BM12_BOVIN", "mass": { "chemical_mass": 33981.0, "monoisotopic_mass": 33981.0 }, "refseq": { "ac": "NP_001290552", "name": "spermidine synthase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290552" }, "gene_names": [ { "name": "SRM", "type": "recommended", "evidence": [ { "id": "E1BM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM12" } ] }, { "name": "SRM", "type": "synonym", "evidence": [ { "id": "NP_001290552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290552" } ] } ], "protein_names": [ { "name": "Spermidine synthase", "type": "recommended", "evidence": [ { "id": "E1BM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM12/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.16", "type": "synonym", "evidence": [ { "id": "E1BM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM12/entry#names_and_taxonomy" } ] }, { "name": "Putrescine aminopropyltransferase", "type": "synonym", "evidence": [ { "id": "E1BM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM12/entry#names_and_taxonomy" } ] }, { "name": "spermidine synthase", "type": "synonym", "evidence": [ { "id": "NP_001290552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290552" } ] } ], "function": [ { "annotation": "Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.", "evidence": [ { "database": "UniProtKB", "id": "E1BM12", "url": "https://www.uniprot.org/uniprotkb/E1BM12#function" }, { "database": "UniProtKB", "id": "ARBA00053963", "url": "https://www.uniprot.org/uniprotkb/ARBA00053963#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM12", "url": "https://www.uniprot.org/uniprotkb/E1BM12" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SRM", "url": "https://www.uniprot.org/uniprotkb/E1BM12", "locus": { "chromosome": "16", "start_pos": 42568355, "end_pos": 42564305, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005304", "url": "https://www.ensembl.org/id/ENSBTAG00000005304" } ] } } ], "crossref": [ { "id": "E1BM12", "url": "https://alphafold.ebi.ac.uk/entry/E1BM12", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005304", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005304", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505916", "url": "https://www.ncbi.nlm.nih.gov/gene/505916", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505916", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505916", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLYHEMM", "url": "https://omabrowser.org/oma/group/FLYHEMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM12", "url": "https://www.orthodb.org/?gene=E1BM12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11558", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11558", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11558:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11558:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01564", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01564", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-351202", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-351202", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001290552", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290552", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12721", "url": "https://www.rhea-db.org/rhea/12721", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BM12", "url": "https://www.uniprot.org/uniprotkb/E1BM12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM12-1", "url": "https://www.uniprot.org/uniprotkb/E1BM12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGPDGPAAPGPAAIREGWFRETCSLWPGQALSLQVEQLLHHQRSRYQDILVFRSKSYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHSSVEAVVQCEIDEDVIQVSKKFLPSMAVGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGILCCQGECQWLHLDLIKEMRHFCKSLFPVVDYAYCTIPTYPSGQIGFMLCSKNPSTNFREPLQPLMQKQVEEMQLKYYNSDVHRAAFVLPEFARKALNDVS", "length": 302, "header": "tr|E1BM12-1|E1BM12_BOVIN Isoform 1 of Spermidine synthase OS=Bos taurus OX=9913 GN=SRM PE=3 SV=2 CANONICAL=E1BM12-1" }, "isoforms": [ { "isoform_ac": "E1BM12-1", "url": "https://www.uniprot.org/uniprotkb/E1BM12/entry#E1BM12-1", "sequence": { "sequence": "MEPGPDGPAAPGPAAIREGWFRETCSLWPGQALSLQVEQLLHHQRSRYQDILVFRSKSYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHSSVEAVVQCEIDEDVIQVSKKFLPSMAVGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGILCCQGECQWLHLDLIKEMRHFCKSLFPVVDYAYCTIPTYPSGQIGFMLCSKNPSTNFREPLQPLMQKQVEEMQLKYYNSDVHRAAFVLPEFARKALNDVS", "length": 302, "header": "tr|E1BM12-1|E1BM12_BOVIN Isoform 1 of Spermidine synthase OS=Bos taurus OX=9913 GN=SRM PE=3 SV=2 CANONICAL=E1BM12-1" }, "locus": { "chromosome": "16", "start_pos": 42568082, "end_pos": 42564401, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006978.5", "url": "https://www.ensembl.org/id/ENSBTAT00000006978.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006978.5", "url": "https://www.ensembl.org/id/ENSBTAP00000006978.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:505916", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505916", "resource": "KEGG Pathway" }, { "id": "R-BTA-351202", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-351202", "resource": "Reactome", "description": "Metabolism of polyamines" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NY06-1", "protein_name": "Spermidine synthase", "gene_name": "SRM", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERGAAALIREGWFRETCRLWPGQAMSLQVEELLHHQRSRYQEILVFRSTTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPDPRKVLIIGGGDGGVLREVVKHPTVESVVQCEIDEDVIQVSKKYLPGMAVGYSSAKLTLHVGDGFEFMKQNQEAFDVIITDSSDPMGPAESLFKESYYQLMKTALREDGILCCQGECQWLHLDLIKEMRQFCKSLFPVVEYAYCTIPTYPSGQIGFMLCSKNPNTNFREPVQQLSQQQVEERSLKYYNSDIHRAAFILPEFARKALSDV", "length": 294 }, "evidence": [ { "id": "E1BM12", "url": "https://omabrowser.org/oma/group/E1BM12/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A480SJI2-1", "protein_name": "Spermidine synthase", "gene_name": "SRM", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPGPDGPAAPGPAAIREGWFHETCSLWPGQALSLQVEQLLHHQRSRYQDILVFRSKSYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPAVESVVQCEIDEDVIQVSKKFLPGMAVSYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEEGILCCQGECQWLHLDLIKEMRQFCKSLFPVVDYAYCTIPTYPSGQIGFMLCSKNPSTNFREPVQLLTQKQVEQRQLRYYNSDVHRAAFVLPEFARKALNDAD", "length": 302 }, "evidence": [ { "id": "E1BM12", "url": "https://omabrowser.org/oma/group/E1BM12/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1R3G8-1", "protein_name": "Spermidine synthase", "gene_name": "srm", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNIKDGWFTETCTLWPGQAMSLQVEEVLYHKKSKFQDVMVFKSKTYGNVLILDGVIQCTERDEFSYQEMIANLPLCCHPCPKKVLIIGGGDGGVLREVVKHPLVESVVQCEIDEDVINVSKKYLPGMAKGFFSPKLTLHVGDGFEFMKKNQDAFDIIITDSSDPVGPAESLFKESYYQLMKTALCEGGILCCQGECQWLHLELIKEMRTFCKTLFPVVDYAYCTIPTYPSGQIGFMLCSKNSKTNFREPLRELTRDEIESMSLKYYNPEIHRAAFILPEFARKVLSEA", "length": 289 }, "evidence": [ { "id": "E1BM12", "url": "https://omabrowser.org/oma/group/E1BM12/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P19623-1", "protein_name": "Spermidine synthase", "gene_name": "SRM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALNDVS", "length": 302 }, "evidence": [ { "id": "E1BM12", "url": "https://omabrowser.org/oma/group/E1BM12/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q12074-1", "protein_name": "Spermidine synthase SPE3", "gene_name": "SPE3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAQEITHPTIVDGWFREISDTMWPGQAMTLKVEKVLHHEKSKYQDVLIFKSTTYGNVLVLDNVIQATERDEFAYQEMIAHLALNSHPNPKKVLVIGGGDGGVLREVVKHDSVEEAWLCDIDEAVIRLSKEYLPEMAASYSHPKVKTHIGDGFQFLRDYQNTFDVIITDSSDPEGPAETLFQKEYFQLLNSALTEKGVITTQAESMWIHLPIIKDLKKACSEVFPVAEYSFVTIPTYPTGTIGFMVCSKDKTCNVKKPLREISDEKEAELYRYYNKKIHEASFVLPTWAAKELN", "length": 293 }, "evidence": [ { "id": "E1BM12", "url": "https://omabrowser.org/oma/group/E1BM12/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q64674-1", "protein_name": "Spermidine synthase", "gene_name": "Srm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGPDGPAAPGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIEVSKKFLPGMAVGFSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGILCCQGECQWLHLDLIKEMRHFCKSLFPVVDYAYCSIPTYPSGQIGFMLCSKNPSTNFREPVQQLTQAQVEQMQLKYYNSDMHRAAFVLPEFTRKALNDIS", "length": 302 }, "evidence": [ { "id": "E1BM12", "url": "https://omabrowser.org/oma/group/E1BM12/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJS8-1", "protein_name": "Mannan-binding lectin serine protease 2", "gene_name": "Masp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLIVLGLLWSLVATLLGSKWPEPVFGRLVSLGFPEKYGNHQDRSWTLTAPPGFRLRLYFTHFNLELSYRCEYDFVKLTSGTKVLATLCGQESTDTERAPGNDTFYSLGPSLKVTFHSDYSNEKPFTGFEAFYAAEDVDECRTSLGDSVPCDHYCHNYLGGYYCSCRVGYILHQNKHTCSALCSGQVFTGRSGFLSSPEYPQPYPKLSSCAYNIRLEEGFSITLDFVESFDVEMHPEAQCPYDSLKIQTDKREYGPFCGKTLPPRIETDSNKVTITFTTDESGNHTGWKIHYTSTAQPCPDPTAPPNGHISPVQATYVLKDSFSVFCKTGFELLQGSVPLKSFTAVCQKDGSWDRPIPECSIIDCGPPDDLPNGHVDYITGPEVTTYKAVIQYSCEETFYTMSSNGKYVCEADGFWTSSKGEKSLPVCKPVCGLSTHTSGGRIIGGQPAKPGDFPWQVLLLGETTAAGALIHDDWVLTAAHAVYGKTEAMSSLDIRMGILKRLSLIYTQAWPEAVFIHEGYTHGAGFDNDIALIKLKNKVTINRNIMPICLPRKEAASLMKTDFVGTVAGWGLTQKGFLARNLMFVDIPIVDHQKCATAYTKQPYPGAKVTVNMLCAGLDRGGKDSCRGDSGGALVFLDNETQRWFVGGIVSWGSINCGGSEQYGVYTKVTNYIPWIENIINNF", "length": 685 }, "evidence": [ { "id": "E1BM12", "url": "https://omabrowser.org/oma/group/E1BM12/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VHA1-1", "protein_name": "Spermidine synthase, isoform A", "gene_name": "SpdS", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDSLNNGWFSELQADLWPGQSFSLKVKEVIHKEKSRFQDIQIVETETYGRCLILDGIIQCTARDEFSYQEMISFLPLCAHPNPKKVLIVGGGDGGVAREVVKHPLVEEVHQVEIDDRVVELSKQYLPAMACGFANEKLKLTIGDGFDYMKKHKNEFDVIITDSSDPIGPAVSLFQESYYELMKHALKDDGIVCSQGGSFWLDLDYIKKTMSGCKEHFAKVAYAVTSVPSYPCGHIGFVMGSLNKNQDFATPKLGKSEIDSIDLRYYSSEVHSAAFALPRWVQKHFYE", "length": 287 }, "evidence": [ { "id": "E1BM12", "url": "https://omabrowser.org/oma/group/E1BM12/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9XY92-1", "protein_name": "Spermidine synthase", "gene_name": "spsA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDKIQNGWFSEISEFWPGNSFSLEVEKVLHHEKSEYQDFLVFKSKSFGNVLVLDGVIQATERDEFAYQEMITHIPLFSHPSPKRVLVVGGGDGGVLREVVKHPLVESVTLCEIDKGVIEASRNFLPNMRVGFDHPKVTLFIGDGMEFMRQRKGEFDVIITDSSDPIGPAQGLFERAYYELLKAALAPGGIVCSQCESMWLHLDTIKGLTTFCKELYPNVEYAYTSIPSYPGGSIGFILCSLGGSTKAPIREITPEVQSQMQYYNGEVHKASFVLPQFAAKKLNL", "length": 284 }, "evidence": [ { "id": "E1BM12", "url": "https://omabrowser.org/oma/group/E1BM12/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BM12", "url": "https://www.uniprot.org/uniprotkb/E1BM12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "E1BM12", "url": "https://www.uniprot.org/uniprotkb/E1BM12" } ], "pmid": "" }, { "name": "spermidine synthase activity", "id": "GO:0004766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004766", "evidence": [ { "database": "UniProtKB", "id": "E1BM12", "url": "https://www.uniprot.org/uniprotkb/E1BM12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermine biosynthetic process", "id": "GO:0006597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006597", "evidence": [ { "database": "UniProtKB", "id": "E1BM12", "url": "https://www.uniprot.org/uniprotkb/E1BM12" } ], "pmid": "" }, { "name": "spermidine biosynthetic process", "id": "GO:0008295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008295", "evidence": [ { "database": "UniProtKB", "id": "E1BM12", "url": "https://www.uniprot.org/uniprotkb/E1BM12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12721", "name": "", "equation": "S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BM12-1" ], "evidence": [ { "id": "12721", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12721" } ] }, { "id": "R-BTA-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29610" ], "output_participant_list": [], "enzyme_list": [ "E1BM12-1" ], "evidence": [ { "id": "R-BTA-351215", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-351215" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29610", "participant_name": "Putrescine [cytosol]", "crossref": [ { "id": "326268", "database": "ChEBI", "url": "" }, { "id": "ZINC000005828633", "database": "ZINC", "url": "" }, { "id": "C00134", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BM12", "gene_name": "SRM", "activity": [ { "ec_number": "2.5.1.16", "activity": "S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+).", "evidence": [ { "id": "E1BM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM12" } ] }, { "ec_number": "2.5.1.16", "activity": "", "evidence": [ { "id": "E1BM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM12" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM12-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 302, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM12-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM12" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM12" }, { "id": "PS51006", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51006" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PABS", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 253, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.16", "ec_name": "S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+).", "evidence": [ { "id": "2.5.1.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.16" }, { "id": "2.5.1.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.16" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BM18", "url": "https://www.uniprot.org/uniprotkb/E1BM18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM18-1", "url": "https://www.uniprot.org/uniprotkb/E1BM18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATALEPEDQDLWEEEGILMVKLEDDFPCRPESVSQRDDPVLETSHQNFRRFRYQEAASPREALIRLRELCRQWLRPERRTKEQILELLVLEQFLTVLPGELQSWVRGQRPESGEEAVTLVEGLQKQPRRPRRWVTVHVHGQEVLSEETVPPGAEPGSPSELQDPAQTLTPEELREETTQSPDLGASEEQTLCQESELQPLQESEVPVLQNPALPEERNSGNSEMVALLTALSQGLVAFKDVAVCFSQDQWSDLDPTQKEFYGEYVLEDDCGIVVSLSFPIPRLDEISHVREEEPLVPDVPEPQEPEEPEILSFTYTGDGSDDEEECPGQEDLSLEDPHRSVSGDTEIHQTPDWEIVFEDDPGRLNERRLGTKMSQVSSSTNLQETMPVHLLLGRHHNCPVCGKSFTCNSHLIRHLRTHTGEKPYKCMECGKSYTRSSHLARHQKVHRTNAPHKYPLNRRSLGEAAPLVQAERTPPVEKPYRCEDCGKHFRWTSDLVRHQRTHTGEKPFFCTICGKSFSQKSVLTTHQRIHLGGKPYLCGECGEDFSDHRRYLAHRKTHAAEELYLCSECGRCFSHSAAFAKHLRGHASVRPCRCSECGKSFSRRDHLIRHQRTHTGEKPFTCPTCGKSFSRGYHLIRHQRTHSQKAS", "length": 648, "header": "tr|E1BM18-1|E1BM18_BOVIN Isoform 1 of Zinc finger protein 202 OS=Bos taurus OX=9913 GN=ZNF202 PE=3 SV=2 CANONICAL=E1BM18-1" }, "isoforms": [ { "isoform_ac": "E1BM18-1", "url": "https://www.uniprot.org/uniprotkb/E1BM18/entry#E1BM18-1", "sequence": { "sequence": "MATALEPEDQDLWEEEGILMVKLEDDFPCRPESVSQRDDPVLETSHQNFRRFRYQEAASPREALIRLRELCRQWLRPERRTKEQILELLVLEQFLTVLPGELQSWVRGQRPESGEEAVTLVEGLQKQPRRPRRWVTVHVHGQEVLSEETVPPGAEPGSPSELQDPAQTLTPEELREETTQSPDLGASEEQTLCQESELQPLQESEVPVLQNPALPEERNSGNSEMVALLTALSQGLVAFKDVAVCFSQDQWSDLDPTQKEFYGEYVLEDDCGIVVSLSFPIPRLDEISHVREEEPLVPDVPEPQEPEEPEILSFTYTGDGSDDEEECPGQEDLSLEDPHRSVSGDTEIHQTPDWEIVFEDDPGRLNERRLGTKMSQVSSSTNLQETMPVHLLLGRHHNCPVCGKSFTCNSHLIRHLRTHTGEKPYKCMECGKSYTRSSHLARHQKVHRTNAPHKYPLNRRSLGEAAPLVQAERTPPVEKPYRCEDCGKHFRWTSDLVRHQRTHTGEKPFFCTICGKSFSQKSVLTTHQRIHLGGKPYLCGECGEDFSDHRRYLAHRKTHAAEELYLCSECGRCFSHSAAFAKHLRGHASVRPCRCSECGKSFSRRDHLIRHQRTHTGEKPFTCPTCGKSFSRGYHLIRHQRTHSQKAS", "length": 648, "header": "tr|E1BM18-1|E1BM18_BOVIN Isoform 1 of Zinc finger protein 202 OS=Bos taurus OX=9913 GN=ZNF202 PE=3 SV=2 CANONICAL=E1BM18-1" }, "locus": { "chromosome": "15", "start_pos": 34315894, "end_pos": 34310779, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022184.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022184.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022184.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022184.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:541023", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541023", "resource": "KEGG Pathway" }, { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K9R2-1", "protein_name": "Zinc finger protein 202", "gene_name": "Zfp202", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATALELEDQDLWEEEEEGVLMVKLEDDFTCGPESALQGDDPVLETSHQNFRCFRYQEASSPREALIRLRELCHQWLRPERRTKEQILELLVLEQFLTVLPGELQSWVRGQRPESGEEAVTLVEGLQKQPRRPRRWVTVHVQGQEVLSEETLHLGVEPESSNEQQEPTQTLTAEQPHEEALRSTDLGTLEQESLQHEGERLPLLESEVPVSQHADLPTEQGSGHPEMVALLTALSQGLVTFKDVALCFSQDQWSDLDPTQKEFYGEYVLEEDCGIVVSLSFPIPRLDDPSQIREEEPQVPGVHESQEPAEPEILSFTYTGDMSEAEEECVEQQDTNKSILANTEIHQTPDWEIVIEDNTSRLNERFGTNVSKVNSFTNIRKTMPVHSQSGRQHHCPLCAKSFTCNSHLIRHLRTHTGEKPYKCMECGKSYTRSSHLARHQKVHKVNTPHKHPPNRKTVDASQVQSEATTRVEKPYTCDDCGKHFRWTSDLVRHQRTHTGEKPFFCTICGKSFSQKSVLTTHQRIHVGGKPYTCANCGENFSEQKQYLAHRKTHVSEENHLCSECGRSFNHSAAFAKHLKGHASVRNCRCDECGKSFSRRDHLVRHQRTHTGEKPFTCATCGKSFSRGYHLIRHQRIHTGKTKT", "length": 643 }, "evidence": [ { "id": "E1BM18", "url": "https://omabrowser.org/oma/group/E1BM18/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95125-1", "protein_name": "Zinc finger protein 202", "gene_name": "ZNF202", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATAVEPEDQDLWEEEGILMVKLEDDFTCRPESVLQRDDPVLETSHQNFRRFRYQEAASPREALIRLRELCHQWLRPERRTKEQILELLVLEQFLTVLPGELQSWVRGQRPESGEEAVTLVEGLQKQPRRPRRWVTVHVHGQEVLSEETVHLGVEPESPNELQDPVQSSTPEQSPEETTQSPDLGAPAEQRPHQEEELQTLQESEVPVPEDPDLPAERSSGDSEMVALLTALSQGLVTFKDVAVCFSQDQWSDLDPTQKEFYGEYVLEEDCGIVVSLSFPIPRPDEISQVREEEPWVPDIQEPQETQEPEILSFTYTGDRSKDEEECLEQEDLSLEDIHRPVLGEPEIHQTPDWEIVFEDNPGRLNERRFGTNISQVNSFVNLRETTPVHPLLGRHHDCSVCGKSFTCNSHLVRHLRTHTGEKPYKCMECGKSYTRSSHLARHQKVHKMNAPYKYPLNRKNLEETSPVTQAERTPSVEKPYRCDDCGKHFRWTSDLVRHQRTHTGEKPFFCTICGKSFSQKSVLTTHQRIHLGGKPYLCGECGEDFSEHRRYLAHRKTHAAEELYLCSECGRCFTHSAAFAKHLRGHASVRPCRCNECGKSFSRRDHLVRHQRTHTGEKPFTCPTCGKSFSRGYHLIRHQRTHSEKTS", "length": 648 }, "evidence": [ { "id": "E1BM18", "url": "https://omabrowser.org/oma/group/E1BM18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": 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], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "LBD domain binding", "id": "GO:0050693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050693", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "DNA binding domain binding", "id": "GO:0050692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050692", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 32, "go_terms": [ { "name": "endocardium formation", "id": "GO:0060214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060214", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "embryonic retina morphogenesis in camera-type eye", "id": "GO:0060059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060059", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "lens placode formation involved in camera-type eye formation", "id": "GO:0046619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046619", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "ventricular cardiac myofibril assembly", "id": "GO:0055005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055005", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "lymphatic endothelial cell fate commitment", "id": "GO:0060838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060838", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "lung development", "id": "GO:0030324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030324", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "negative regulation of viral genome replication", "id": "GO:0045071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045071", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "positive regulation of heart growth", "id": "GO:0060421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060421", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "skeletal muscle thin filament assembly", "id": "GO:0030240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030240", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "pancreas development", "id": "GO:0031016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031016", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "lymphangiogenesis", "id": "GO:0001946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001946", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "positive regulation of cell cycle", "id": "GO:0045787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045787", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "ventricular septum morphogenesis", "id": "GO:0060412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060412", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "positive regulation of neural precursor cell proliferation", "id": "GO:2000179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000179", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "hepatocyte differentiation", "id": "GO:0070365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070365", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "neuronal stem cell population maintenance", "id": "GO:0097150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097150", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "aorta smooth muscle tissue morphogenesis", "id": "GO:0060414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060414", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "dentate gyrus development", "id": "GO:0021542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021542", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "positive regulation of vascular endothelial growth factor signaling pathway", "id": "GO:1900748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900748", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "atrial cardiac muscle tissue morphogenesis", "id": "GO:0055009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055009", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "ventricular cardiac muscle tissue morphogenesis", "id": "GO:0055010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055010", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" }, { "name": "positive regulation of sarcomere organization", "id": "GO:0060298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060298", "evidence": [ { "database": "UniProtKB", "id": "E1BM20", "url": "https://www.uniprot.org/uniprotkb/E1BM20" } ], "pmid": "" 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"MDPGEAAILDSSPRSFSRLFALPPPLSAAFLGRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPSQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHVGDNSRAINTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ", "length": 598, "header": "tr|E1BM34-1|E1BM34_BOVIN Isoform 1 of Anaphase-promoting complex subunit 7 OS=Bos taurus OX=9913 GN=ANAPC7 PE=3 SV=3 CANONICAL=E1BM34-1" }, "isoforms": [ { "isoform_ac": "E1BM34-1", "url": "https://www.uniprot.org/uniprotkb/E1BM34/entry#E1BM34-1", "sequence": { "sequence": "MDPGEAAILDSSPRSFSRLFALPPPLSAAFLGRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPSQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHVGDNSRAINTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ", "length": 598, "header": "tr|E1BM34-1|E1BM34_BOVIN Isoform 1 of Anaphase-promoting complex subunit 7 OS=Bos taurus OX=9913 GN=ANAPC7 PE=3 SV=3 CANONICAL=E1BM34-1" }, "locus": { "chromosome": "17", "start_pos": 54312144, "end_pos": 54292128, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022173.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022173.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022173.6", "url": "https://www.ensembl.org/id/ENSBTAP00000022173.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 558, "start_aa": "Thr", "end_pos": 558, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr558", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:535072", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535072", "resource": "KEGG Pathway" }, { "id": "R-BTA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-BTA-174048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174048", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Cyclin B" }, { "id": "R-BTA-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-BTA-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-BTA-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-BTA-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-BTA-176407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176407", "resource": "Reactome", "description": "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" }, { "id": "R-BTA-176408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176408", "resource": "Reactome", "description": "Regulation of APC/C activators between G1/S and early anaphase" }, { "id": "R-BTA-176409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176409", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of mitotic proteins" }, { "id": "R-BTA-176412", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176412", "resource": "Reactome", "description": "Phosphorylation of the APC/C" }, { "id": "R-BTA-179409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-179409", "resource": "Reactome", "description": "APC-Cdc20 mediated degradation of Nek2A" }, { "id": "R-BTA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-BTA-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-BTA-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-BTA-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A9C3Q3-1", "protein_name": "Anaphase-promoting complex subunit 7", "gene_name": "anapc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNVIDHVRDMAAAGLHSNVRIISSLLLTMSTNNPELFSPSQKYQLLVYHADAIFHDKEYRNAACKYNMALQQKKMLSKTSKVRPSSTGSTTSAVQAQNLPSEIEVKYKIAECYTILKLDKDAISVLDGIPSRQRTPKINMMLANLYRKAGQERSAVTSYKEVLRQCPLALDAIIGLLSLSVKGAEVASMTMDVIQSIPNLDWLSVWIKAHAFIHGGDNQRAINTICSLEKKSLLRDNVDLLVTLADVYFRAGDTKNSILKFEQAQMLDPYLIKGMDVYGYLMAREGHLEDVEVLGGRLFNISDQHAEPWVISGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGVALRNMGRVQEAIIHFREAMRLAPCRLDCYEGLIDCYLASNGIREAMGMANNIYKTLGANAQTLTILATVCLEDPMTQEKAKTLLDKALAQRPDYIKAVVKKAELLSREQKYEEGIALLRNTLANQSDCVLHRMLGDFLVAVNDYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATVELDGDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ", "length": 566 }, "evidence": [ { "id": "E1BM34", "url": "https://omabrowser.org/oma/group/E1BM34/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZIT4-1", "protein_name": "Anaphase-promoting complex subunit 7", "gene_name": "Anapc7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMGQPLSPHDCLFLRRHIRSNLYLRGAEPRLDQKDPAAAAILELSLRLGSAPGGSVSCCWVTVSPGRMSVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPSQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKLDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVSVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEGSPTDATQEDDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ", "length": 632 }, "evidence": [ { "id": "E1BM34", "url": "https://omabrowser.org/oma/group/E1BM34/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H237-1", "protein_name": "Anaphase-promoting complex subunit 7", "gene_name": "Anapc7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPSQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKAWSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKLDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLGSLADLYFRAGDSKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASSSIREAMVMANNVYKTLGASAQTLTLLATVCLEDPVTQEKAKALLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ", "length": 565 }, "evidence": [ { "id": "E1BM34", "url": "https://omabrowser.org/oma/group/E1BM34/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3L7Q8-1", "protein_name": "Anaphase-promoting complex subunit 7", "gene_name": "ANAPC7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPSQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ", "length": 565 }, "evidence": [ { "id": "E1BM34", "url": "https://omabrowser.org/oma/group/E1BM34/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54D58-1", "protein_name": "Anaphase-promoting complex subunit 7", "gene_name": "anapc7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQQLPMVNVELMISNLRILVESKQFSSAEFLGNFVISVPNQQKTPHQNIISFSLFGDSLFGKNEFVRSLKYFKQSLDILFKVYNNPNNNNNNNNKQADFDNKQFEYELKYKISLCYIKINRNNLAISYLESIPFSSRGLDTHLTIARLYKDIGKEKSKECIISYKEVIKLCPLCLEAINSLKEMGENVDQVLIPSINKFQQKNNSFNSNNIIDLSWISLLSMSQYEMKRNQPEKSLILLKKVESKFSTNLYVLEKLALSYLYHDEPSIINTFNIFQKIRLLDPYYIGSMDIFCSLLKRRSLQFELNKVCNDLVASNPYCAETWTSVALFYFLKENVEKSLENVDRAISIKESHEFAHSLKGEILLSLDEPREALPSLERAFQLSKNILTARELVRCHLILNQMKEALVVAETINNLSPDYSKTMALLGMVLANQPEEREEARKILTKALTLSPHCTDTVLTLSKLNVVEGRFQEAIDILNSQLEYQETDLMHTEIAGVYLTKDYHEDAMIHYNSALEINPQYEPASRGIARLELIMKGIDPDQELDQENDDDDQEEGEGENDQEENDDDDNDDDDEYIS", "length": 580 }, "evidence": [ { "id": "E1BM34", "url": "https://omabrowser.org/oma/group/E1BM34/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VY89-1", "protein_name": "Anaphase-promoting complex subunit 7", "gene_name": "APC7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVPKEQIATLIEHGLYDSAEMLGCFLVSSPTVSAETSPQLKAENLILLGDALFHQREHRRAIHTYKQALHHYTRIPKQSSGISRSSLSLSTRSSVNASSISAINENEVRFKIASSHFALNETKAAIAEMESVKTRSLEMNILMAKLHRNSGYNRGAIAFYKECLRQCPYVLEAVIGLAELGVSAKDIISSFTQTSNRSAKVSLDQIDPTRWLQRYVEAQCCVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPYTLTSMDEYAMLLQIKCDYSRLNKLVHDLLSVDHTRAEVFVALSVLWERKDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEAAAIAFRAAQNLRSDLRSYQGLVHSYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAFTSSGREKAKKFYESGLRLEPGYLGAVLALAELHLMEGRNGDAVSLLERYLKDYADDSLHVKLAQVFAATNMLQDSLSHFQAALRINPQNEAAKKGLDRLEKQMKGIDPDATDENDENDVEDVDGDTEEAELM", "length": 558 }, "evidence": [ { "id": "E1BM34", "url": "https://omabrowser.org/oma/group/E1BM34/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UJX3-1", "protein_name": "Anaphase-promoting complex subunit 7", "gene_name": "ANAPC7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ", "length": 565 }, "evidence": [ { "id": "E1BM34", "url": "https://omabrowser.org/oma/group/E1BM34/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W3Y6-1", "protein_name": "Anaphase promoting complex subunit 7, isoform A", "gene_name": "APC7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASFLIVVEKMEIALFANAKKLYDHKLYECVIPAADLLRTVLKNDRYVATLDVEYQVLLYLLNANYKERNYRAALRHFDEIIHKRRLMMRHKNAVLVAIESSYPEFGDAEQRRRAAECYRQIGNTDMAIETLLQVPPTLRSPRINLMLARLQHHGSRHGTTKKSEAVLAYKEVIRECPMALQVIEALLELGVNGNEINSLVMHAATVPDHFDWLSKWIKALAQMFNFKHSDASQTFLMLHDNTTLRCNEHLMMALGKCLYYNGDYFQAEDIFSSTLCANPDNVEAIGLMAVLCGQEGGCEQDSADMDYLFAKVSSEVKYTASHWFAHAQLLYDEGKFERGLNFVEKCLDSEPRNHEALILRGRLLIALERHTQAVCAFRTAQMVAPYRFEIYRGLFHSYLAQKRFKEANALCNWTIRLFQNSPRSFTMFGRTLFLFPDPRMRRTARKFAEKSLKINHIYTPAVNLIADICQVEGPTKAIIKLLEKHVIIFPKVNLLNHLGDIMRKQKEPVKAMEYYYKALRQDPKSKRTLRGLRLLAKSDDESPVLDESDDIGMDNQQSINDLTTLCEATNAQGAEGAESVENSREASSSAAARSGQEEDVDEHDWIDVPDGMSY", "length": 615 }, "evidence": [ { "id": "E1BM34", "url": "https://omabrowser.org/oma/group/E1BM34/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WVM3-1", "protein_name": "Anaphase-promoting complex subunit 7", "gene_name": "Anapc7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPSQKYQLLVYHADSLFHDKEYRNAVSKYAMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKLDKDAIAVLDGIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLGSLADLYFRAGDSKNSVLKFEQAQMLDPYLIRGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ", "length": 565 }, "evidence": [ { "id": "E1BM34", "url": "https://omabrowser.org/oma/group/E1BM34/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E1BM34", "url": "https://www.uniprot.org/uniprotkb/E1BM34" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "E1BM34", "url": "https://www.uniprot.org/uniprotkb/E1BM34" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BM34", "url": "https://www.uniprot.org/uniprotkb/E1BM34" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "E1BM34", "url": "https://www.uniprot.org/uniprotkb/E1BM34" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "E1BM34", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM68-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 322, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM68-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM68" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM68" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 78 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"E1BM70", "uniprot_id": "CCD39_BOVIN", "mass": { "chemical_mass": 110372.0, "monoisotopic_mass": 110372.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC39", "type": "recommended", "evidence": [ { "id": "E1BM70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM70" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 39", "type": "recommended", "evidence": [ { "id": "E1BM70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM70/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.", "evidence": [ { "database": "UniProtKB", "id": "E1BM70", "url": "https://www.uniprot.org/uniprotkb/E1BM70#function" }, { "database": "UniProtKB", "id": "Q9UFE4", "url": "https://www.uniprot.org/uniprotkb/Q9UFE4#function" }, { "database": "UniProtKB", "id": "A8IQT2", "url": "https://www.uniprot.org/uniprotkb/A8IQT2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM70", "url": "https://www.uniprot.org/uniprotkb/E1BM70" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC39", "url": "https://www.uniprot.org/uniprotkb/E1BM70", "locus": { "chromosome": "1", "start_pos": 86371093, "end_pos": 86318639, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001969", "url": "https://www.ensembl.org/id/ENSBTAG00000001969" } ] } } ], "crossref": [ { "id": "E1BM70", "url": "https://alphafold.ebi.ac.uk/entry/E1BM70", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR033290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BM70", "url": "https://www.orthodb.org/?gene=E1BM70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18962", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18962", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18962:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18962:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24161", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24161", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BM70", "url": "https://www.uniprot.org/uniprotkb/E1BM70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM70-1", "url": "https://www.uniprot.org/uniprotkb/E1BM70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSEFLAELRWEDGFAIPVANEENKTLEEQLSKLQDERSSMQDQLRDYEDRINAMTSHFKNVKQEFLFTQSLCKARDHEIESEEHFKMIAERELGRVKDEIQRLENEITSIREKKNDKENSIFKTTQKLDGLKCQMNWDQQALEAWLEESAHKDSDALTLQKYAQQDDNKIRALTLQLERLTVECNQRRKVLDNEFAETLSVQLELDKAAQDFRKIHNERQKLILQWESTIEQMQKRDKDIDNCAVALARIKQEIREKENLVKEKIKFLENEIGNNTEYEKKISVADRKVLKCRTEYQRHEANRIQLKDELDSLKATVNRSSSDLEALRKNISKVKMDINEETARLGKIKNHNQIVRKKLKEITEKTMSVEEKATNLEDMLREEERGVKEVEVQLNIVKDVLFKKVQELQTETMKEKALVSEIEGTRSSLKHLNHQLHKLDFETLQQQEIMYAQDFYIQQVERRMSRLKGDINSEEKQALEAKTVELQKTLEEKKSALCLLETQIKKLHNDLYFTKKSNSKYRDEKQSLMTKINELTLFNDRSEKELTKAKALKQDLMIEDNLLKLEVKRTRELLHSKAEEVLSLEKRKQQLHTAMEERTEEIKVHKTMLASQIRYVDQERQNVSAEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQAYYVIKQALVNNQMEKTGRSYEEEYSFVPMRIYDLVNQVQEINAWCCMSVPRSFQKVTPSSAEYEVKIQLEEQKRAVDEKYRYKQRQIRELQEDIQSMENTLTVIEHLTNNVKEKVTEKQAYVLQLNRETEEQKPKLERVTKQCAKLTKEVRLLKDTKDETLEEQDIKLREVKQLHKIIDEMIVDITQENAEIGVILQTYFQQSGLELPTTSTKGSRHSSRSPSQTSLLSARSSKSTSTSASQTSIKVLELNFPASPLTGSTSRPTSASSASSTGKSRKTNK", "length": 942, "header": "sp|E1BM70-1|CCD39_BOVIN Isoform 1 of Coiled-coil domain-containing protein 39 OS=Bos taurus OX=9913 GN=CCDC39 PE=3 SV=1 CANONICAL=E1BM70-1" }, "isoforms": [ { "isoform_ac": "E1BM70-1", "url": "https://www.uniprot.org/uniprotkb/E1BM70/entry#E1BM70-1", "sequence": { "sequence": 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Isoform 1 of Coiled-coil domain-containing protein 39 OS=Bos taurus OX=9913 GN=CCDC39 PE=3 SV=1 CANONICAL=E1BM70-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 894, "end_pos": 894, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "E1BM70", "url": "https://www.uniprot.org/uniprotkb/E1BM70" } ], "site_lbl": "Ser894" }, { "start_pos": 902, "end_pos": 902, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "E1BM70", "url": "https://www.uniprot.org/uniprotkb/E1BM70" } ], "site_lbl": "Ser902" } ], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BM70", "url": "https://www.uniprot.org/uniprotkb/E1BM70" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "E1BM70", "url": "https://www.uniprot.org/uniprotkb/E1BM70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "inner dynein arm assembly", "id": "GO:0036159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036159", "evidence": [ { "database": "UniProtKB", "id": "E1BM70", "url": "https://www.uniprot.org/uniprotkb/E1BM70" } ], "pmid": "" }, { "name": "cilium-dependent cell motility", "id": "GO:0060285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060285", "evidence": [ { "database": "UniProtKB", "id": "E1BM70", "url": "https://www.uniprot.org/uniprotkb/E1BM70" } ], "pmid": "" }, { "name": "epithelial cilium movement involved in determination of left/right asymmetry", "id": "GO:0060287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060287", "evidence": [ { "database": "UniProtKB", "id": "E1BM70", "url": "https://www.uniprot.org/uniprotkb/E1BM70" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "E1BM70", "url": "https://www.uniprot.org/uniprotkb/E1BM70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM70-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 942, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM70-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM70" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 894, 902 ], "sequon_annotation_sites": [ { "start_pos": 24, "end_pos": 26 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 623, "end_pos": 625 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10812", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10812:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10812:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03299", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03299", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8866904", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866904", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8866907", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866907", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BM80", "url": "https://www.uniprot.org/uniprotkb/E1BM80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM80-1", "url": "https://www.uniprot.org/uniprotkb/E1BM80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVHTYSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPTAADFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHDEPPGLLAPPARALGLDPRRDYAAAAVPRLLQGLTEGAHGLADAPLGLQGLAAPPGLEDLQAMDEPGMSLLDQSVIKKVPIPSKASSLSALSLAKDSLVGGITNPSEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHGRKSMLLAAKQICKEFADLMAQDRSPLGNTRPALILEPGVQSCLTHFSLITHGFGGPAICAALNAFQNYLLESLKGLDKMFLSSAGSGHGDTKASEKDAKHRK", "length": 440, "header": "tr|E1BM80-1|E1BM80_BOVIN Isoform 1 of Transcription factor AP-2 epsilon OS=Bos taurus OX=9913 GN=TFAP2E PE=3 SV=4 CANONICAL=E1BM80-1" }, "isoforms": [ { "isoform_ac": "E1BM80-1", "url": "https://www.uniprot.org/uniprotkb/E1BM80/entry#E1BM80-1", "sequence": { "sequence": "MLVHTYSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPTAADFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHDEPPGLLAPPARALGLDPRRDYAAAAVPRLLQGLTEGAHGLADAPLGLQGLAAPPGLEDLQAMDEPGMSLLDQSVIKKVPIPSKASSLSALSLAKDSLVGGITNPSEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHGRKSMLLAAKQICKEFADLMAQDRSPLGNTRPALILEPGVQSCLTHFSLITHGFGGPAICAALNAFQNYLLESLKGLDKMFLSSAGSGHGDTKASEKDAKHRK", "length": 440, "header": "tr|E1BM80-1|E1BM80_BOVIN Isoform 1 of Transcription factor AP-2 epsilon OS=Bos taurus OX=9913 GN=TFAP2E PE=3 SV=4 CANONICAL=E1BM80-1" }, "locus": { "chromosome": "3", "start_pos": 110194927, "end_pos": 110179929, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002546.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002546.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002546.7", "url": "https://www.ensembl.org/id/ENSBTAP00000002546.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8866904", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866904", "resource": "Reactome", "description": "Negative regulation of activity of TFAP2 (AP-2) family transcription factors" }, { "id": "R-BTA-8866907", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866907", "resource": "Reactome", "description": "Activation of the TFAP2 (AP-2) family of transcription factors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BM80", "url": "https://www.uniprot.org/uniprotkb/E1BM80" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BM80", "url": "https://www.uniprot.org/uniprotkb/E1BM80" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "E1BM80", "url": "https://www.uniprot.org/uniprotkb/E1BM80" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BM80", "url": "https://www.uniprot.org/uniprotkb/E1BM80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BM80", "url": "https://www.uniprot.org/uniprotkb/E1BM80" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "E1BM80", "url": "https://www.uniprot.org/uniprotkb/E1BM80" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BM80", "url": "https://www.uniprot.org/uniprotkb/E1BM80" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BM80", "url": "https://www.uniprot.org/uniprotkb/E1BM80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM80-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 440, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM80-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM80" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM80" }, { "id": "PF03299", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03299" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transcription factor AP-2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 216, "end_pos": 408, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 250, "end_pos": 252 }, { "start_pos": 290, "end_pos": 292 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"evidence": [ { "id": "XP_002695801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695801" } ] } ], "protein_names": [ { "name": "Nuclear cap-binding protein subunit 3", "type": "recommended", "evidence": [ { "id": "E1BM89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM89/entry#names_and_taxonomy" } ] }, { "name": "nuclear cap-binding protein subunit 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002695801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695801" } ] } ], "function": [ { "annotation": "Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth.", "evidence": [ { "database": "UniProtKB", "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89#function" }, { "database": "UniProtKB", "id": "ARBA00055272", "url": "https://www.uniprot.org/uniprotkb/ARBA00055272#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NCBP3", "url": "https://www.uniprot.org/uniprotkb/E1BM89", "locus": { "chromosome": "19", "start_pos": 24463018, "end_pos": 24488770, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016621", "url": "https://www.ensembl.org/id/ENSBTAG00000016621" } ] } } ], "crossref": [ { "id": "E1BM89", "url": "https://alphafold.ebi.ac.uk/entry/E1BM89", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016621", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016621", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510317", "url": "https://www.ncbi.nlm.nih.gov/gene/510317", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510317", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510317", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QYSRPRP", "url": "https://omabrowser.org/oma/group/QYSRPRP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM89", "url": "https://www.orthodb.org/?gene=E1BM89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16291", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16291", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16291:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16291:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10309", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10309", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002695801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695801", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM89-1", "url": "https://www.uniprot.org/uniprotkb/E1BM89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVRGLRVSVKAEAPAGPALGLPSPETGLDRGEPEPMEVEEGELEVVPVRRSLKELIPDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSSLPALDKIRSKDANEEKSSEKSKKDKQEDSSDDDEAEEGEVEDETTSDVELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEQDMDADDRVVVEYHAELPALKQTRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADTLSTSNIKNRIGNKLPAEKFADVRHLLDEKRQHTRPRPAGSSTKTDIRQRLGKRPYSPEKAFGSNPVVRREPFSDVHSRLGVPRQDVKGLYSDTREKKSGSLWTRLGSAPKTKEKNTKKGDHRAPGTEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES", "length": 610, "header": "tr|E1BM89-1|E1BM89_BOVIN Isoform 1 of Nuclear cap-binding protein subunit 3 OS=Bos taurus OX=9913 GN=NCBP3 PE=3 SV=1 CANONICAL=E1BM89-1" }, "isoforms": [ { "isoform_ac": "E1BM89-1", "url": "https://www.uniprot.org/uniprotkb/E1BM89/entry#E1BM89-1", "sequence": { "sequence": "MAAVRGLRVSVKAEAPAGPALGLPSPETGLDRGEPEPMEVEEGELEVVPVRRSLKELIPDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSSLPALDKIRSKDANEEKSSEKSKKDKQEDSSDDDEAEEGEVEDETTSDVELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEQDMDADDRVVVEYHAELPALKQTRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADTLSTSNIKNRIGNKLPAEKFADVRHLLDEKRQHTRPRPAGSSTKTDIRQRLGKRPYSPEKAFGSNPVVRREPFSDVHSRLGVPRQDVKGLYSDTREKKSGSLWTRLGSAPKTKEKNTKKGDHRAPGTEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES", "length": 610, "header": "tr|E1BM89-1|E1BM89_BOVIN Isoform 1 of Nuclear cap-binding protein subunit 3 OS=Bos taurus OX=9913 GN=NCBP3 PE=3 SV=1 CANONICAL=E1BM89-1" }, "locus": { "chromosome": "19", "start_pos": 24488571, "end_pos": 24464022, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022110.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022110.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022110.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022110.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:510317", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510317", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZXL5-1", "protein_name": "Nuclear cap-binding protein subunit 3", "gene_name": "Ncbp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVRGLRVSVKAEAPAGPALGLPSPEVESGLERGEPEPMEVEEGELEIVPVRRSLKELLPDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRAEVNLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDIFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSSLPAQDKIRSREASEDKSSEKDKKDKQEDSSDDDETEEGEVEDENSSDVELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEQEEEDQDMDADDRVVVEYHEELPALKQPRERSMSRRSSASSSDSDEMDYDLELRMISTPSPKKSMKMTMYADEVESQLKSIRNPMRSDSISTSNIKNRIGNKLPPEKFADVRHLLEEKRQHSCPRPAGGSTKPDIRQRLGKRPYSPEKAFSSNQVVRREPSSDVHSRLGVPRQDVKGLYSDTRERKSGGLWTRLGSTPKTKEKNTKKVDHRASGTEEDDSELQRAWGALIKEKEQSRQKKSRLDSLPSLQIEVSRESSSGSEAES", "length": 615 }, "evidence": [ { "id": "E1BM89", "url": "https://omabrowser.org/oma/group/E1BM89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RGS3-1", "protein_name": "Nuclear cap-binding protein subunit 3", "gene_name": "NCBP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAVRGLRVSVKAEAPAGPALGPLSPEAESGLDRGEPEPMEVEEGELEIVPVRRSLKELIPDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLSQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDIFSYFKEYPPAHIEWLDDTSCNVVWLDEMTAARALINMSSLPALDKIRSRDASEDKSSEKSKKDKQEDSSDDDEAEEGEVEDENSSDAELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEGEDQDMDADDRVVVEYHEELPALKQTRERSTSRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADTLSTSNIKNRIGNKLPPEKFADVRHLLDEKRQHTRPRPPSSNTKTDIRQRLGKRPYSPEKPFSSNPVVRREPFSDVHSRLGVPRQDVKGLYSDTREKKSGSLWTRLGSATKTKEKNTKKVDHRTPGTEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES", "length": 615 }, "evidence": [ { "id": "E1BM89", "url": "https://omabrowser.org/oma/group/E1BM89/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q53F19-1", "protein_name": "Nuclear cap-binding protein subunit 3", "gene_name": "NCBP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVRGLRVSVKAEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRRSLKELIPDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSSLPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES", "length": 620 }, "evidence": [ { "id": "E1BM89", "url": "https://omabrowser.org/oma/group/E1BM89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BZR9-1", "protein_name": "Nuclear cap-binding protein subunit 3", "gene_name": "Ncbp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVRGLRVSVKAEAPAGPALGLPSPEVESGLERGEPEPMEVEEGELEIVPVRRSLKELLPDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRAEVNLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDIFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSSLPAQDKMRSRDASEDKSSEKNKKDKQEDSSDDDETEEGEVEDENSSDVELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEDQDMDADDRVVVEYHEELPGLKQPRERSLSRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKSIRNPMRADSISTSNIKNRIGNKLPPEKFADVRHLLDEKRQHSCPRPAVSSTKPDIRQRLGKRPYSPEKAFSSNQVVRREPSSDVHSRLGVPRQDVKGLYSDTRERKSGGLWTRLGSTPKTKEKNTKKVDHRASGAEEDDSELQRAWGALIKEKEESRQKKSRLDSLPSLQIEVSRESSSGSEAES", "length": 615 }, "evidence": [ { "id": "E1BM89", "url": "https://omabrowser.org/oma/group/E1BM89/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89" } ], "pmid": "" }, { "name": "RNA 7-methylguanosine cap binding", "id": "GO:0000340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000340", "evidence": [ { "database": "UniProtKB", "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89" } ], "pmid": "" }, { "name": "RNA cap binding", "id": "GO:0000339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000339", "evidence": [ { "database": "UniProtKB", "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89" } ], "pmid": "" }, { "name": "7-methylguanosine mRNA capping", "id": "GO:0006370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006370", "evidence": [ { "database": "UniProtKB", "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89" } ], "pmid": "" }, { "name": "snRNA export from nucleus", "id": "GO:0006408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006408", "evidence": [ { "database": "UniProtKB", "id": "E1BM89", "url": "https://www.uniprot.org/uniprotkb/E1BM89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM89-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 610, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM89-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM89" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM91-1", "uniprot_ac": "E1BM91", "uniprot_id": "E1BM91_BOVIN", "mass": { "chemical_mass": 106845.0, "monoisotopic_mass": 106845.0 }, "refseq": { "ac": "NP_001179614", "name": "desmoglein-3 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179614" }, "gene_names": [ { "name": "DSG3", "type": "recommended", "evidence": [ { "id": "E1BM91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ] }, { "name": "DSG3", "type": "synonym", "evidence": [ { "id": "NP_001179614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179614" } ] } ], "protein_names": [ { "name": "Desmoglein 3", "type": "synonym", "evidence": [ { "id": "E1BM91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM91/entry#names_and_taxonomy" } ] }, { "name": "desmoglein 3 (pemphigus vulgaris antigen)", "type": "synonym", "evidence": [ { "id": "NP_001179614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179614" } ] }, { "name": "desmoglein-3 precursor", "type": "synonym", "evidence": [ { "id": "NP_001179614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179614" } ] } ], "function": [ { "annotation": "A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91#function" }, { "database": "UniProtKB", "id": "RU004358", "url": "https://www.uniprot.org/uniprotkb/RU004358#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DSG3", "url": "https://www.uniprot.org/uniprotkb/E1BM91", "locus": { "chromosome": "24", "start_pos": 25667567, "end_pos": 25698964, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000039483", "url": "https://www.ensembl.org/id/ENSBTAG00000039483" } ] } } ], "crossref": [ { "id": "E1BM91", "url": "https://alphafold.ebi.ac.uk/entry/E1BM91", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000039483", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039483", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "529902", "url": "https://www.ncbi.nlm.nih.gov/gene/529902", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000233", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000233", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:529902", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529902", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQCDNRD", "url": "https://omabrowser.org/oma/group/CQCDNRD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM91", "url": "https://www.orthodb.org/?gene=E1BM91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24025:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24025:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-351906", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-351906", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179614", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM91-1", "url": "https://www.uniprot.org/uniprotkb/E1BM91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWLPFRTTGALAILMVVLLVHGELRIQTKGQYEEYETAIQGKRRYKREWVKFARPCREGEDNSNRNPIAKITSDFEATQKITYHISGIGIDQPPFGIFVVDRNTGEINITAIVDREVTPSFQITCRALNALGQDVEKPLILTVKILDINDNAPVFSQSIFQGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIISQEPAGTSMFLLSRHTGEVRTLTNSLDREQVSSYRLVVSGADRDGEGLSSQCECSIKVKDVNDNFPTFRESQYLARIEENTLSSELLRIQVIDLDEEFTDNWLADFFFTSGNEGHWFEIETDPRTNEGILKVVKSLDYEQVQSMQLGIAVKNKAEFHQSVISQYQVQSTPLIVQVINVREGIAFRPSSKTFTVRKGISSRQLINYVLGTYQAIDEDTGEVASFVRYVLGRNDGGLLMIDSETAGIKFVKNIDRDVTFIVNKTITAEVLAIDGNTGKTSTGTIFVLVPDFNEKCPTIALEKEAVCSSSPSVVVRASPLERDKYAGPYEFSVEHQSLKLPVVWSISGRDATSALLTAPQPVSPGVYRISVMVTDSEGRRCEEPESLTLEVCQCDYRDICPNVYPTSIPNPIIGERSGRMGAAAIGLLFLGLLLLLLALLLLLTCDCGAGPIGGVTGGFVPVPDGSEGTIHPWGIEGAQPEDKEITNIGVPPITANGVDFMENSEVCTNTYAGGTVVEGASGMELTTNLGAAAGSGGAAGFGATAGLSNFSVGQSGTMRTRHSTGGTNKDFGEGAINMKFLDSYFSQKAFACADEDDSQEANDCLLVYDNEGIEAPSSPVGSLGCCSFIADDFDESFLDSLGPKFKKLAEISLGMDDETKSSQPPTKDSSSRVDACGQHVQVQQSESVRYQTLSGSQGASALSASSSVLQPAVSITDPLQHGSYLVTETYSASSGSLVQPPAAVFDPLLTQNVIVTERVICPTPSITGNLHGPTELRGSDSKIFTEDPSSRLI", "length": 988, "header": "tr|E1BM91-1|E1BM91_BOVIN Isoform 1 of Desmoglein 3 OS=Bos taurus OX=9913 GN=DSG3 PE=4 SV=1 CANONICAL=E1BM91-1" }, "isoforms": [ { "isoform_ac": "E1BM91-1", "url": "https://www.uniprot.org/uniprotkb/E1BM91/entry#E1BM91-1", "sequence": { "sequence": "MAWLPFRTTGALAILMVVLLVHGELRIQTKGQYEEYETAIQGKRRYKREWVKFARPCREGEDNSNRNPIAKITSDFEATQKITYHISGIGIDQPPFGIFVVDRNTGEINITAIVDREVTPSFQITCRALNALGQDVEKPLILTVKILDINDNAPVFSQSIFQGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIISQEPAGTSMFLLSRHTGEVRTLTNSLDREQVSSYRLVVSGADRDGEGLSSQCECSIKVKDVNDNFPTFRESQYLARIEENTLSSELLRIQVIDLDEEFTDNWLADFFFTSGNEGHWFEIETDPRTNEGILKVVKSLDYEQVQSMQLGIAVKNKAEFHQSVISQYQVQSTPLIVQVINVREGIAFRPSSKTFTVRKGISSRQLINYVLGTYQAIDEDTGEVASFVRYVLGRNDGGLLMIDSETAGIKFVKNIDRDVTFIVNKTITAEVLAIDGNTGKTSTGTIFVLVPDFNEKCPTIALEKEAVCSSSPSVVVRASPLERDKYAGPYEFSVEHQSLKLPVVWSISGRDATSALLTAPQPVSPGVYRISVMVTDSEGRRCEEPESLTLEVCQCDYRDICPNVYPTSIPNPIIGERSGRMGAAAIGLLFLGLLLLLLALLLLLTCDCGAGPIGGVTGGFVPVPDGSEGTIHPWGIEGAQPEDKEITNIGVPPITANGVDFMENSEVCTNTYAGGTVVEGASGMELTTNLGAAAGSGGAAGFGATAGLSNFSVGQSGTMRTRHSTGGTNKDFGEGAINMKFLDSYFSQKAFACADEDDSQEANDCLLVYDNEGIEAPSSPVGSLGCCSFIADDFDESFLDSLGPKFKKLAEISLGMDDETKSSQPPTKDSSSRVDACGQHVQVQQSESVRYQTLSGSQGASALSASSSVLQPAVSITDPLQHGSYLVTETYSASSGSLVQPPAAVFDPLLTQNVIVTERVICPTPSITGNLHGPTELRGSDSKIFTEDPSSRLI", "length": 988, "header": "tr|E1BM91-1|E1BM91_BOVIN Isoform 1 of Desmoglein 3 OS=Bos taurus OX=9913 GN=DSG3 PE=4 SV=1 CANONICAL=E1BM91-1" }, "locus": { "chromosome": "24", "start_pos": 25698881, "end_pos": 25668352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002538.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002538.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002538.4", "url": "https://www.ensembl.org/id/ENSBTAP00000002538.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 958, "start_aa": "Thr", "end_pos": 958, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr958", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:529902", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529902", "resource": "KEGG Pathway" }, { "id": "R-BTA-351906", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-351906", "resource": "Reactome", "description": "Apoptotic cleavage of cell adhesion proteins" }, { "id": "R-BTA-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-BTA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZL74-1", "protein_name": "Desmoglein 3", "gene_name": "Dsg3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVYGELHIESGGQHREDRMALQLTKRRYKREWVKFAKPCREREDNSKRNPIAKITSDFQKNQKITYRISGVGIDQPPFGIFVVDPNNGDINITAIVDREETPSFLITCRALNALGQDVERPLILTVKILDVNDNAPIFSQTIFKGEIEENSASNSLVMILNATDADEPNHMNSKIAFKIVSQEPAGMSMFLISRNTGEVRTLTSSLDREQVGSYHLIVSGADNDGTGLSTQCECSIKIKDVNDNFPVLTDSQYSARIEENTLNSELLRFQVTDWDEEYTDNWLAVYFFTSGNEGNWFEIETDPRTNEGILKLVKVLDYEQMQSMQFSIAVRNKAEFHQSVISQYQVQSTPVTIQVINVQEGISFRPPSRTFTVQRGVSINKLAGYILGTYQATDEDTGKAASSVRYVLGRNDGGFLVIDSKTAEIKFVKNINRDSTFIVNKTISAEVLAIDENTGKTSTGTVYVEVPSFNENCPSVVLEKREICTSSPSVTLSVRTLDRAKYTGPYTVSLEEQPLKLPVVWTITTLNATSALLQAQQHISPGVYNVPVIVKDNQDGQCDTLESLTLTVCQCDDRSMCRAPGPSREPFIREESTWRLGPAAIGLILLGLLMLLLAPLLLLTCDCGSGPIGGAGTGGFVPVPDGSEGTIHQWGIEGAQPEDKEITNICVPPVTSNGADFMESSEVCTNTYAGGTLVEGASGMEMTTKLGGATGSGAAVALGLGHSGTMRTRHSTGGTLKDYAAPVNMTFLGSYFSQKSSAYAEEEDDREVNDCLLIYDDEGEDAAPRSPALSSCSFMADDLDDSFLDSLGPKFKKLAEICLGVDDEAKQVKPGPKDSSSGADACARPTEALQAGSNRYQTLPGGLEVTQSGSNRYQTLPGGLEVTQSGSNRYQTLPGGLEVTQSGSKVCHVLPGNQDTSVLSSSGSVHPAIAIPDPLQLGNYLLTETYTTSGSFVQPTTATFDPHVTQNVTVTERVICPLPSASGSIVAPTELRGSYSMLYTKEACSHL", "length": 1007 }, "evidence": [ { "id": "E1BM91", "url": "https://omabrowser.org/oma/group/E1BM91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LU54-1", "protein_name": "Desmoglein 3", "gene_name": "DSG3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAWRLFRTTGALAILMVVLLVHGELRIETKGQHGEYETEVQQAKRRYKREWVKFARPCREGEDNSKRNPIAKITSDFQATQKITYRISGIGIDQPPYGIFVVDKNTGEINITAIVDREETPSFQITCRALNALGQDVEKPLILTVKILDINDNPPVFSQSVFMGEIEENSASNSLVMMLNATDADEPNHLNSKIAFKILSQEPAGTPMFLLSRHTGEVRTLTSSLDREQISSYRLVVSGADKDGEGLASQCECSIKVKDVNDNFPRLRESQYIARIEENTLSSDLLRLQVIDLDEEFTDNWLAVYFFTSGNEGKWFEIETDSRTNEGILKVVKSLDYEQLQSVQLGIAVKNKAEFHKSVISQYRVQSTPLTIQVINVREGIAFRPASKTFVVQQGISSRKLINYVLGTYQAIDEDTNKAASSVRYILGRNDGGLLIIDSKTAQIKFAKNIDRDATFIVNRTITAEVLAIDENTGKTSTGTVYVKVPDFNENCPTIALEKETICSSSPSVVVSARAVDKDKFTVPYTFSLEDQPLKLPVVWSIASLDDTSALLRAPQQISPGVYRISLVVTDSQGRRCETPESLTLEVCQCDSRDTCGTPVPTKTPSTENGKTSSWRLGPAAIGLLLLGLLMLLLAPLLLLTCDCGRGPIGGVTGGFIPVPDGSEGTIHPWGIEGAHPEDKEITNIRVPPISSNGVDFMENSEVCTNTYAGGTVVEGASGMELTTKLGAAGGSGAAAGFGAAAGLSIYSAGQSGTMRTRHSTGGTNKDYGEGAVNMNFLDSYFSQKAFACAEEDDGHEANDCLLIYDNEGTGVPGSPVGSLGCCSFIADEWDDGFLDSLGPKFKKLAEISLGMDDEAKKSQPPAKDSGSGVESCGQSVQVQQSESVCYQTLSGSQGASALSASSSVLQPAISIPDPLQQGSYLVTETYSASGSLMQPSTAVFDPLLTQNVIVTERVICPISSVPGNLHAPTELPGSCNQICTEDPCSRLI", "length": 989 }, "evidence": [ { "id": "E1BM91", "url": "https://omabrowser.org/oma/group/E1BM91/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P32926-1", "protein_name": "Desmoglein-3", "gene_name": "DSG3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMGLFPRTTGALAIFVVVILVHGELRIETKGQYDEEEMTMQQAKRRQKREWVKFAKPCREGEDNSKRNPIAKITSDYQATQKITYRISGVGIDQPPFGIFVVDKNTGDINITAIVDREETPSFLITCRALNAQGLDVEKPLILTVKILDINDNPPVFSQQIFMGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIVSQEPAGTPMFLLSRNTGEVRTLTNSLDREQASSYRLVVSGADKDGEGLSTQCECNIKVKDVNDNFPMFRDSQYSARIEENILSSELLRFQVTDLDEEYTDNWLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDYEQLQSVKLSIAVKNKAEFHQSVISRYRVQSTPVTIQVINVREGIAFRPASKTFTVQKGISSKKLVDYILGTYQAIDEDTNKAASNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDSTFIVNKTITAEVLAIDEYTGKTSTGTVYVRVPDFNDNCPTAVLEKDAVCSSSPSVVVSARTLNNRYTGPYTFALEDQPVKLPAVWSITTLNATSALLRAQEQIPPGVYHISLVLTDSQNNRCEMPRSLTLEVCQCDNRGICGTSYPTTSPGTRYGRPHSGRLGPAAIGLLLLGLLLLLLAPLLLLTCDCGAGSTGGVTGGFIPVPDGSEGTIHQWGIEGAHPEDKEITNICVPPVTANGADFMESSEVCTNTYARGTAVEGTSGMEMTTKLGAATESGGAAGFATGTVSGAASGFGAATGVGICSSGQSGTMRTRHSTGGTNKDYADGAISMNFLDSYFSQKAFACAEEDDGQEANDCLLIYDNEGADATGSPVGSVGCCSFIADDLDDSFLDSLGPKFKKLAEISLGVDGEGKEVQPPSKDSGYGIESCGHPIEVQQTGFVKCQTLSGSQGASALSTSGSVQPAVSIPDPLQHGNYLVTETYSASGSLVQPSTAGFDPLLTQNVIVTERVICPISSVPGNLAGPTQLRGSHTMLCTEDPCSRLI", "length": 999 }, "evidence": [ { "id": "E1BM91", "url": "https://omabrowser.org/oma/group/E1BM91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "tight junction assembly", "id": "GO:0120192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120192", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" }, { "name": "adherens junction assembly", "id": "GO:0034333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034333", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" }, { "name": "desmosome assembly", "id": "GO:0002159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002159", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" }, { "name": "negative regulation of p38MAPK cascade", "id": "GO:1903753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903753", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" }, { "name": "positive regulation of protein localization to membrane", "id": "GO:1905477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905477", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" }, { "name": "positive regulation of protein localization to adherens junction", "id": "GO:1904704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904704", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BM91", "url": "https://www.uniprot.org/uniprotkb/E1BM91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM91-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 988, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM91-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM91" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM91" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 156, "start_aa": "Asp", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 958 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 458, "end_pos": 460 }, { "start_pos": 744, "end_pos": 746 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM92-1", "uniprot_ac": "E1BM92", "uniprot_id": "E1BM92_BOVIN", "mass": { "chemical_mass": 91521.0, "monoisotopic_mass": 91521.0 }, "refseq": { "ac": "XP_002691205", "name": "prominin-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691205" }, "gene_names": [ { "name": "PROM2", "type": "recommended", "evidence": [ { "id": "E1BM92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ] }, { "name": "PROM2", "type": "synonym", "evidence": [ { "id": "XP_002691205", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691205" } ] } ], "protein_names": [ { "name": "Prominin 2", "type": "synonym", "evidence": [ { "id": "E1BM92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM92/entry#names_and_taxonomy" } ] }, { "name": "prominin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002691205", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691205" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PROM2", "url": "https://www.uniprot.org/uniprotkb/E1BM92", "locus": { "chromosome": "11", "start_pos": 2032794, "end_pos": 2017963, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001952", "url": "https://www.ensembl.org/id/ENSBTAG00000001952" } ] } } ], "crossref": [ { "id": "E1BM92", "url": "https://alphafold.ebi.ac.uk/entry/E1BM92", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001952", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001952", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "520936", "url": "https://www.ncbi.nlm.nih.gov/gene/520936", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:520936", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520936", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CRSWENG", "url": "https://omabrowser.org/oma/group/CRSWENG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM92", "url": "https://www.orthodb.org/?gene=E1BM92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22730", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22730", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22730:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22730:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05478", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05478", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002691205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691205", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM92-1", "url": "https://www.uniprot.org/uniprotkb/E1BM92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRSPDLLAALLGLGLGAVLTLPGAGAAGCRALGPAERLVFAPAAKARWLAPRVRAPGPLDSLYGTVRGFLSVVQLNPFPAELIKTLLNEPASVKVDEVVRYQAGYVVCAVIAGLYLLAMPTAGLCFCCLRCRRRCGGRVKMEHKAMACERAVLVTFLLLTTLVLLIGVVTAFVTNQHMHEQMGPSAEAVPETLLSLRGLVSEVPLELQAVAEQFSLPQEQVLKELNGVGSSIGKAIHSQLKSTMYEALASVLSLGQALQVSVDHLRGLNATSVELQEGQEALAPALHGHRQRLLSLLQEPPCQGCAGALDKSHTLELGADFSQVPSVDHVLHRLKGVPEANFYSMVLEENTTFNALPILAALQTADMISELKKVVAEQPRGLNTMGEAFPVWEAASRWSQALEEVEERSRPFLEEVQSYERYRWIAGCVLCSVVLLVVVCNLLGLNLGIWGLSAREDPSHSEAKGESGARFLMVGVGFSFLFAVPLIILIFSTFLVGGNVQTLVCQSWESGELYEFVDTPGNLPPSMNLSQLLGLKKNLSILLAYEQCKQGAVLWTVLQLNDSYDLEKHLDISQYTIKLQQELQKLKVDVKNLDLLSPAARRDLEALQSSGLESIHYPGFLAEIQKPVVNSDVEKLAQELEGLSQTQGNATLGQKLQEEARGLQHLHQEKILPQQNLVAKLNRSVQALASSAPHLQSEISGVLDRVTHLKEELPTWATHILRNESECFLKREMGYFSQYMAWVREEVTQRIATCQPLSGALDSGRVILCDMVADPWNAFWFCLGWCTFFLIPSIVFAIKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL", "length": 833, "header": "tr|E1BM92-1|E1BM92_BOVIN Isoform 1 of Prominin 2 OS=Bos taurus OX=9913 GN=PROM2 PE=3 SV=2 CANONICAL=E1BM92-1" }, "isoforms": [ { "isoform_ac": "E1BM92-1", "url": "https://www.uniprot.org/uniprotkb/E1BM92/entry#E1BM92-1", "sequence": { "sequence": "MVRSPDLLAALLGLGLGAVLTLPGAGAAGCRALGPAERLVFAPAAKARWLAPRVRAPGPLDSLYGTVRGFLSVVQLNPFPAELIKTLLNEPASVKVDEVVRYQAGYVVCAVIAGLYLLAMPTAGLCFCCLRCRRRCGGRVKMEHKAMACERAVLVTFLLLTTLVLLIGVVTAFVTNQHMHEQMGPSAEAVPETLLSLRGLVSEVPLELQAVAEQFSLPQEQVLKELNGVGSSIGKAIHSQLKSTMYEALASVLSLGQALQVSVDHLRGLNATSVELQEGQEALAPALHGHRQRLLSLLQEPPCQGCAGALDKSHTLELGADFSQVPSVDHVLHRLKGVPEANFYSMVLEENTTFNALPILAALQTADMISELKKVVAEQPRGLNTMGEAFPVWEAASRWSQALEEVEERSRPFLEEVQSYERYRWIAGCVLCSVVLLVVVCNLLGLNLGIWGLSAREDPSHSEAKGESGARFLMVGVGFSFLFAVPLIILIFSTFLVGGNVQTLVCQSWESGELYEFVDTPGNLPPSMNLSQLLGLKKNLSILLAYEQCKQGAVLWTVLQLNDSYDLEKHLDISQYTIKLQQELQKLKVDVKNLDLLSPAARRDLEALQSSGLESIHYPGFLAEIQKPVVNSDVEKLAQELEGLSQTQGNATLGQKLQEEARGLQHLHQEKILPQQNLVAKLNRSVQALASSAPHLQSEISGVLDRVTHLKEELPTWATHILRNESECFLKREMGYFSQYMAWVREEVTQRIATCQPLSGALDSGRVILCDMVADPWNAFWFCLGWCTFFLIPSIVFAIKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL", "length": 833, "header": "tr|E1BM92-1|E1BM92_BOVIN Isoform 1 of Prominin 2 OS=Bos taurus OX=9913 GN=PROM2 PE=3 SV=2 CANONICAL=E1BM92-1" }, "locus": { "chromosome": "11", "start_pos": 2032780, "end_pos": 2018162, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002536.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002536.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002536.4", "url": "https://www.ensembl.org/id/ENSBTAP00000002536.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:520936", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520936", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3UUY6-1", "protein_name": "Prominin-2", "gene_name": "Prom2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRSPGLMVPLLGLSLGLALSLPEAVTDDCGSLGRVEHLAFARVPRTRELAPLVRASGPLNSLYGTVRRFLSVVQLNPFPAELIKTLLNDPSSVKTDEVVRYEAGYVVCAVIAGLYLLLVPITGLCFCCCRCRQRCGGRVKTEHKAMACERGTLMIFLLLTTLVLLIGMVCAFATNQHTHSQTGPSVKAVPETLLSLRGLVSDVPEELRAIAEQFSVPQKQVSKELDGVGENLGNVIHNRLKSTVYPVLASVHSLGQALQVSIDHLRALNTTSVELQEAQRHLEPPVQAHRERLLALLQDSWCHEENCKRVLSQAGALQLGADFSQTPPVDDVLHRLKDVPETNFSSMVQEEKATFNNLPLLVQVQAVSVVKDVKKALAEQPEGLRMLAQAFPGSEAASRWSQALEGLEQRSRPYLQEVQQYETYRWILGCVLCSAILLVVICNLLGLSLGIWGLFAREDPSHSETKGEAGARLLMAGVAFSFLFAVPLILLVFVTFLVGGNVQTLVCRSWESGELYEFADTPGNLPPSMNLSYLLGLKKNISIVQAYRQCKAGAVLWKVLQLNDSYDLDKHLDIKQYTHKIQQELQSFQVDLKELDLLSPTARQDLEALQRSGLEKIHYRGFLVQIQKPVVNTDMWQLAQELEGLAQAQNDSLLRQQLREEARELRSLYQEKVVPQESLVTKLNFSVKTLESLAPSLQVNTSDFLDSVTRLKGELPVQINHILRNATECFLTREMGYFSQYVTWVRAEVTQRIATCQPFSTALDNGHVILCDMMADPWNAFWFCLGWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL", "length": 835 }, "evidence": [ { "id": "E1BM92", "url": "https://omabrowser.org/oma/group/E1BM92/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N271-1", "protein_name": "Prominin-2", "gene_name": "PROM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKHTLALLAPLLGLGLGLALSQLAAGATDCKFLGPAEHLTFTPAARARWLAPRVRAPGLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVNEVVRYEAGYVVCAVIAGLYLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALACERAALMVFLLLTTLLLLIGVVCAFVTNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLPQEQVSEELDGVGVSIGSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVELQAGQQDLEPAIREHRDRLLELLQEARCQGDCAGALSWARTLELGADFSQVPSVDHVLHQLKGVPEANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFPGLEAASRWAQALQEVEESSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLGIWGLSARDDPSHPEAKGEAGARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCQSWENGELFEFADTPGNLPPSMNLSQLLGLRKNISIHQAYQQCKEGAALWTVLQLNDSYDLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLVQIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAKLNLSVRALESSAPNLQLETSDVLANVTYLKGELPAWAARILRNVSECFLAREMGYFSQYVAWVREEVTQRIATCQPLSGALDNSRVILCDMMADPWNAFWFCLAWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL", "length": 834 }, "evidence": [ { "id": "E1BM92", "url": "https://omabrowser.org/oma/group/E1BM92/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of pinocytosis", "id": "GO:0048550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048550", "evidence": [ { "database": "UniProtKB", "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ], "pmid": "" }, { "name": "microvillus organization", "id": "GO:0032528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032528", "evidence": [ { "database": "UniProtKB", "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ], "pmid": "" }, { "name": "positive regulation of cell projection organization", "id": "GO:0031346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031346", "evidence": [ { "database": "UniProtKB", "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ], "pmid": "" }, { "name": "negative regulation of caveolin-mediated endocytosis", "id": "GO:2001287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001287", "evidence": [ { "database": "UniProtKB", "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ], "pmid": "" }, { "name": "microvillus membrane", "id": "GO:0031528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031528", "evidence": [ { "database": "UniProtKB", "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ], "pmid": "" }, { "name": "prominosome", "id": "GO:0071914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071914", "evidence": [ { "database": "UniProtKB", "id": "E1BM92", "url": "https://www.uniprot.org/uniprotkb/E1BM92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM92-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 833, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM92-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM92" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 270, "end_pos": 272 }, { "start_pos": 351, "end_pos": 353 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 650, "end_pos": 652 }, { "start_pos": 683, "end_pos": 685 }, { "start_pos": 724, "end_pos": 726 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BM96-1", "uniprot_ac": "E1BM96", "uniprot_id": "E1BM96_BOVIN", "mass": { "chemical_mass": 161494.0, "monoisotopic_mass": 161494.0 }, "refseq": { "ac": "XP_005204188", "name": "membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204188" }, "gene_names": [ { "name": "MAGI3", "type": "recommended", "evidence": [ { "id": "E1BM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM96" } ] }, { "name": "MAGI3", "type": "synonym", "evidence": [ { "id": "XP_005204188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204188" } ] } ], "protein_names": [ { "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "E1BM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM96/entry#names_and_taxonomy" } ] }, { "name": "Membrane-associated guanylate kinase inverted 3", "type": "synonym", "evidence": [ { "id": "E1BM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM96/entry#names_and_taxonomy" } ] }, { "name": "membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005204188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204188" } ] } ], "function": [ { "annotation": "Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.", "evidence": [ { "database": "UniProtKB", "id": "E1BM96", "url": "https://www.uniprot.org/uniprotkb/E1BM96#function" }, { "database": "UniProtKB", "id": "ARBA00056578", "url": "https://www.uniprot.org/uniprotkb/ARBA00056578#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM96", "url": "https://www.uniprot.org/uniprotkb/E1BM96" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MAGI3", "url": "https://www.uniprot.org/uniprotkb/E1BM96", "locus": { "chromosome": "3", "start_pos": 29703286, "end_pos": 29962236, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019611", "url": "https://www.ensembl.org/id/ENSBTAG00000019611" } ] } } ], "crossref": [ { "id": "ENSBTAG00000019611", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019611", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06730", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06730", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06731", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06731", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06732", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06732", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06733", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06733", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06734", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06734", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06735", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06735", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532952", "url": "https://www.ncbi.nlm.nih.gov/gene/532952", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BM96", "url": "https://www.orthodb.org/?gene=E1BM96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10316", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10316", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10316:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10316:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005204188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204188", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BM96", "url": "https://www.uniprot.org/uniprotkb/E1BM96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM96-1", "url": "https://www.uniprot.org/uniprotkb/E1BM96-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKTLKKKKHWLSKVQECAVSWAGAPGDLGAEIRGGAERGEFPYLGRLREDPGGGTCCVVSGKAPSPGDVLLEVNGTPVSGLTNRDTLAVIRHFREPIRLKTVKPGKVINKDLRHYLSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGTLLESGTYDGNFYGTPKPPAEPSPFQADPVDQVLFDNEFDTESQRKRTTSVSKMERMDSSLPEEEEDEDKEAVNGSGNAAENRERHSEPSDWIKTVPSYNQTNSSMDFRNYMMRDENLEPLPKNWEMAYTDTGMIYFIDHNTKTTTWLDPRLCKKAKAPEDCEDGELPYGWEKIEDPQYGTYYVDHLNQKTQFENPVEEAKRKKQLGQADTGSSKPDTEKSHFTRDPSQLKGILVRASLKKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGNCVLGHTHADVVQMFQLVPVNQYVNLTLCRGYPLPDDNEDPVVDIVAATPVINGQSLTKGETCMNTQDFKSGAVVLDQNGKSGHSLISDRFNGASDLSEQRASMASSGSSQPELVTIPLIKGPKGFGFAIADSPTGQKVKMILDSQWCQGLQKGDIIKEIYHQNVQNLTHLQVVEVLKQFPVGADVPLLILRGGPPSPTKTAKLKTDKKETSESLEAINEPVPQPMPFPPSIIRSGSPKLDPSEVYLKSKTLYEDKPPNTKDLDVFLRKQESGFGFRVLGGDGPDQSIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLMTTAARNGHVLLTVRRKIFYGEKQPEDDSSQAFPSTQNGSPRLNRAEVLARPAPQEPYDVVLQRKENEGFGFVILTSKSKPPPGVIPHKIGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTLTVIAEEEHLGPPSGTNSARQSPALQHRPMGQSQANHIPGDRSATEGEIGKDVSISYRHSWSDHKHLAQPDTATISVVGGRHNQGLGCYPVELERGPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGTGLIPDHGDWDTNSPPSPNVIYDEQSPCHPPSHSASIFEESHVPVTEESLMRVQICEKAEELKDTVPEKKSTLNENQSDIKHKSLLHKNVNKRDPPNSHGHGDKKNLLKAENGITPRGRSASPKKSASQHLEEHAGKIPSPLKNDPKRRPRDRSLSPRKGENKSSQLGVGTASGQDHCGKSRGRSSSPKKQQKTEGSKDQSNASRRAGGHASDSAEQISDAKERSGVFGRDTNLSQPGKNRTRSPEKKSKRVDERSLPSKKTNNVTSRAIPENERGKKATSGQMSSSKDKTGENVRISEKKLKQEPDERMALSKTEDHKRKELEVADKNKEGGGFKPESGSPAKKTPITPGPWKVPSASRAAGATGVAEKRL", "length": 1475, "header": "tr|E1BM96-1|E1BM96_BOVIN Isoform 1 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 OS=Bos taurus OX=9913 GN=MAGI3 PE=3 SV=3 CANONICAL=E1BM96-1" }, "isoforms": [ { "isoform_ac": "E1BM96-1", "url": "https://www.uniprot.org/uniprotkb/E1BM96/entry#E1BM96-1", "sequence": { "sequence": "MSKTLKKKKHWLSKVQECAVSWAGAPGDLGAEIRGGAERGEFPYLGRLREDPGGGTCCVVSGKAPSPGDVLLEVNGTPVSGLTNRDTLAVIRHFREPIRLKTVKPGKVINKDLRHYLSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGTLLESGTYDGNFYGTPKPPAEPSPFQADPVDQVLFDNEFDTESQRKRTTSVSKMERMDSSLPEEEEDEDKEAVNGSGNAAENRERHSEPSDWIKTVPSYNQTNSSMDFRNYMMRDENLEPLPKNWEMAYTDTGMIYFIDHNTKTTTWLDPRLCKKAKAPEDCEDGELPYGWEKIEDPQYGTYYVDHLNQKTQFENPVEEAKRKKQLGQADTGSSKPDTEKSHFTRDPSQLKGILVRASLKKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGNCVLGHTHADVVQMFQLVPVNQYVNLTLCRGYPLPDDNEDPVVDIVAATPVINGQSLTKGETCMNTQDFKSGAVVLDQNGKSGHSLISDRFNGASDLSEQRASMASSGSSQPELVTIPLIKGPKGFGFAIADSPTGQKVKMILDSQWCQGLQKGDIIKEIYHQNVQNLTHLQVVEVLKQFPVGADVPLLILRGGPPSPTKTAKLKTDKKETSESLEAINEPVPQPMPFPPSIIRSGSPKLDPSEVYLKSKTLYEDKPPNTKDLDVFLRKQESGFGFRVLGGDGPDQSIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLMTTAARNGHVLLTVRRKIFYGEKQPEDDSSQAFPSTQNGSPRLNRAEVLARPAPQEPYDVVLQRKENEGFGFVILTSKSKPPPGVIPHKIGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTLTVIAEEEHLGPPSGTNSARQSPALQHRPMGQSQANHIPGDRSATEGEIGKDVSISYRHSWSDHKHLAQPDTATISVVGGRHNQGLGCYPVELERGPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGTGLIPDHGDWDTNSPPSPNVIYDEQSPCHPPSHSASIFEESHVPVTEESLMRVQICEKAEELKDTVPEKKSTLNENQSDIKHKSLLHKNVNKRDPPNSHGHGDKKNLLKAENGITPRGRSASPKKSASQHLEEHAGKIPSPLKNDPKRRPRDRSLSPRKGENKSSQLGVGTASGQDHCGKSRGRSSSPKKQQKTEGSKDQSNASRRAGGHASDSAEQISDAKERSGVFGRDTNLSQPGKNRTRSPEKKSKRVDERSLPSKKTNNVTSRAIPENERGKKATSGQMSSSKDKTGENVRISEKKLKQEPDERMALSKTEDHKRKELEVADKNKEGGGFKPESGSPAKKTPITPGPWKVPSASRAAGATGVAEKRL", "length": 1475, "header": "tr|E1BM96-1|E1BM96_BOVIN Isoform 1 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 OS=Bos taurus OX=9913 GN=MAGI3 PE=3 SV=3 CANONICAL=E1BM96-1" }, "locus": { "chromosome": "3", "start_pos": 29962037, "end_pos": 29705220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061528.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061528.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053286.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053286.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "E1BM96", "url": "https://www.uniprot.org/uniprotkb/E1BM96" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BM96", "url": "https://www.uniprot.org/uniprotkb/E1BM96" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BM96", "url": "https://www.uniprot.org/uniprotkb/E1BM96" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BM96", "url": "https://www.uniprot.org/uniprotkb/E1BM96" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BM96", "url": "https://www.uniprot.org/uniprotkb/E1BM96" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "E1BM96", "url": "https://www.uniprot.org/uniprotkb/E1BM96" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "E1BM96", "url": "https://www.uniprot.org/uniprotkb/E1BM96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BM96", "url": "https://www.uniprot.org/uniprotkb/E1BM96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1179, "end_pos": 1181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1265, "end_pos": 1267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1305, "end_pos": 1307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1336, "end_pos": 1338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1343, "end_pos": 1345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1367, "end_pos": 1369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 831, "end_pos": 833, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM96" }, { "id": "PS50052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 190, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM96" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 106, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM96" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 294, "end_pos": 327, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1179, "end_pos": 1181 }, { "start_pos": 1265, "end_pos": 1267 }, { "start_pos": 1305, "end_pos": 1307 }, { "start_pos": 1336, "end_pos": 1338 }, { "start_pos": 1343, "end_pos": 1345 }, { "start_pos": 1367, "end_pos": 1369 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 831, "end_pos": 833 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMB9-1", "uniprot_ac": "E1BMB9", "uniprot_id": "E1BMB9_BOVIN", "mass": { "chemical_mass": 58602.0, "monoisotopic_mass": 58602.0 }, "refseq": { "ac": "XP_002693934", "name": "solute carrier family 45 member 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693934" }, "gene_names": [ { "name": "SLC45A3", "type": "recommended", "evidence": [ { "id": "E1BMB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMB9" } ] }, { "name": "SLC45A3", "type": "synonym", "evidence": [ { "id": "XP_002693934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693934" } ] } ], "protein_names": [ { "name": "Solute carrier family 45 member 3", "type": "synonym", "evidence": [ { "id": "E1BMB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMB9/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 45 member 3", "type": "synonym", "evidence": [ { "id": "XP_002693934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693934" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMB9", "url": "https://www.uniprot.org/uniprotkb/E1BMB9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC45A3", "url": "https://www.uniprot.org/uniprotkb/E1BMB9", "locus": { "chromosome": "16", "start_pos": 3410077, "end_pos": 3416912, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007693", "url": "https://www.ensembl.org/id/ENSBTAG00000007693" } ] } } ], "crossref": [ { "id": "E1BMB9", "url": "https://alphafold.ebi.ac.uk/entry/E1BMB9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007693", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007693", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17313", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17313", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "524303", "url": "https://www.ncbi.nlm.nih.gov/gene/524303", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524303", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524303", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQWYALF", "url": "https://omabrowser.org/oma/group/FQWYALF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMB9", "url": "https://www.orthodb.org/?gene=E1BMB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19432", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19432", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19432:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19432:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-189200", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002693934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693934", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BMB9", "url": "https://www.uniprot.org/uniprotkb/E1BMB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMB9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQRLWAGRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLFSVPLLGSASDHWRGRYGRRRPFIWALSLGVLLSLFLIPRASWLAGLLCPDARPLELALLILGVGLLAFCGQLCFTPLEALLSDLFRDPDHCRQAFSVYAFMIGLGGCLGYLLPAIDWDASALAPYLGTQEECLFGLLALIFLTCVAATAFVAEEAALGPAEPAEGLSAPSVPPCCPGRARLALRSLGALCPWLRRLCCRTPRALRRLFVAELCSWMAFMTFTLFYTDFVGEGLYQGVPGAEPGTEARRHYDEGVRMGSLGLFLQCAISLLFSLVMDRLVQRFGTRAVYLASVVAFPVAAGATCLSRSVAVVTASAALTGVTFSALQILPYTLASLYHREKQVFLPKYRGDDGGGAGEDGVMTSFLPGPKAASPFPHGHGGPGGLLAAPPALCGASACEGSVRTAVAEPPEARAIPGRGICLDLAILDSAFLLSQVAPSLFMGFIVQLSQSVTAYMVSAAGLGLVAIYFVTQVVFDKSDLAKYSV", "length": 550, "header": "tr|E1BMB9-1|E1BMB9_BOVIN Isoform 1 of Solute carrier family 45 member 3 OS=Bos taurus OX=9913 GN=SLC45A3 PE=3 SV=1 CANONICAL=E1BMB9-1" }, "isoforms": [ { "isoform_ac": "E1BMB9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMB9/entry#E1BMB9-1", "sequence": { "sequence": "MVQRLWAGRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLFSVPLLGSASDHWRGRYGRRRPFIWALSLGVLLSLFLIPRASWLAGLLCPDARPLELALLILGVGLLAFCGQLCFTPLEALLSDLFRDPDHCRQAFSVYAFMIGLGGCLGYLLPAIDWDASALAPYLGTQEECLFGLLALIFLTCVAATAFVAEEAALGPAEPAEGLSAPSVPPCCPGRARLALRSLGALCPWLRRLCCRTPRALRRLFVAELCSWMAFMTFTLFYTDFVGEGLYQGVPGAEPGTEARRHYDEGVRMGSLGLFLQCAISLLFSLVMDRLVQRFGTRAVYLASVVAFPVAAGATCLSRSVAVVTASAALTGVTFSALQILPYTLASLYHREKQVFLPKYRGDDGGGAGEDGVMTSFLPGPKAASPFPHGHGGPGGLLAAPPALCGASACEGSVRTAVAEPPEARAIPGRGICLDLAILDSAFLLSQVAPSLFMGFIVQLSQSVTAYMVSAAGLGLVAIYFVTQVVFDKSDLAKYSV", "length": 550, "header": "tr|E1BMB9-1|E1BMB9_BOVIN Isoform 1 of Solute carrier family 45 member 3 OS=Bos taurus OX=9913 GN=SLC45A3 PE=3 SV=1 CANONICAL=E1BMB9-1" }, "locus": { "chromosome": "16", "start_pos": 3416689, "end_pos": 3411081, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010116.6", "url": "https://www.ensembl.org/id/ENSBTAT00000010116.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010116.4", "url": "https://www.ensembl.org/id/ENSBTAP00000010116.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:524303", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524303", "resource": "KEGG Pathway" }, { "id": "R-BTA-189200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189200", "resource": "Reactome", "description": "Cellular hexose transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AF62-1", "protein_name": "Solute carrier family 45 member 3", "gene_name": "SLC45A3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGWQKWVPGRVLGSWWQQGGEAGASGARPSWSSSEVHERARALPTRPIMVQRLWMSRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASDHWRGRYGRRRPFIWALSLGVLLSLFLIPRAGRLAGLLCPDTRPLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAFSVYAFMISLGGCLGYLLPAIDWDASALAPYLGTQEECLFGLLSLIFLTCVTATLFVAEEAALGPAEPAEGLSVPSMPSYCCPCRARLAFRNLGALFPRLHQLCCRMPRTLRRLFVAELCSWMAFMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYDEGVRMGSLGLFLQCAISLLFSLVMDRLVQRFGTRAVYLASVVAFPVAAGATCLSRSVAVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDDGAGASEDSLMTSFPPGPKAASPFPNGHIGAGGSSLLASPPTLCGTSACDVSMRAVVGEPPEARVVPGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSESVTAYMVSAAGLGLVAIYFVTQVVFDKSDLAKYSV", "length": 602 }, "evidence": [ { "id": "E1BMB9", "url": "https://omabrowser.org/oma/group/E1BMB9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1AEA4-1", "protein_name": "Solute carrier family 45 member 3", "gene_name": "SLC45A3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALSVLLRNRRAQLLLLNSLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVFVPLIGSASDHWHSSYGRRRPFIWVLCLGVLLSLFIIPHASSLASLFALNARPLEIAFLILGIGMLDFCGQVCFTPLEALLSDLFQEPDNCRQAFSMYAFMISLGGCIGYLLPAIDWGASFLAPYLGGQETCLFSLLAVIFLGCVLATLFVTEEAAAQVDALDGPVLKDALPNPSPSACCSCQLSRSLLQARHVMQALRNLCTLVPRLHSLYCRIPKVIRRLFVAELCSWMALMTFMLFYTDFVGEGLYLGVPRAKPGTDARRRYDEGVRMGSLGLFLQCVTSIFFSTIMDRMVKQFGTRAVYLASVVFFPAAAFVMCLSHSVIVVTISAALTGFTFSALQILPYTLASLYHHEKQVFLHKYKSKEEKDAARSDKKSAFPKGHLSNQKLPYQNGHAGGLYSSSSSSSSPPAASSALCGSSSCDVSLMMMVGESDSVPPGRGICLDLAILDSAFLLSQVVPSLFMGSIVQFTQSVTAYMVSAAGLGLVAIYFATKVVFDKSDMAKYSV", "length": 569 }, "evidence": [ { "id": "E1BMB9", "url": "https://omabrowser.org/oma/group/E1BMB9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZPP5-1", "protein_name": "Solute carrier family 45, member 3", "gene_name": "Slc45a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPGPLTALSIMIQRLWASRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASDQWRGRYGRRRPFIWALSLGVLLSLFLIPRAGWLAGLLCSDTRPLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAFSVYAFMISLGGCLGYLLPAIDWDTSALAPYLGTQEECLFGLLTLIFLICVAATLLVAEEAVLGPPEPAEGLLVSSVSRRCCSCHAGLAFRNLGTLFPRLHQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYDEGIRMGSLGLFLQCAISLFFSLVMDRLVQKFGTRSVYLASVMTFPVAAAATCLSHSVVVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDAGGGSSEDSQTTSFLLGPKPGAPFPNGHVGPGGSSILVPPPALCGASACDVSMRVVVGEPPEAKVVTGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSHSVTAYMVSAAGLGLVAIYFATQVVFDKNDLAKYSL", "length": 564 }, "evidence": [ { "id": "E1BMB9", "url": "https://omabrowser.org/oma/group/E1BMB9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K0H7-1", "protein_name": "Solute carrier family 45 member 3", "gene_name": "Slc45a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIQRLWASRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASDQWRGRYGRRRPFIWALSLGVLLSLFLIPRAGWLAGLLYPDTRPLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAFSVYAFMISLGGCLGYLLPAIDWDTSVLAPYLGTQEECLFGLLTLIFLICMAATLFVTEEAVLGPPEPAEGLLVSAVSRRCCPCHVGLAFRNLGTLFPRLQQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYDEGIRMGSLGLFLQCAISLVFSLVMDRLVQKFGTRSVYLASVMTFPVAAAATCLSHSVVVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDAGGSSGEDSQTTSFLPGPKPGALFPNGHVGSGSSGILAPPPALCGASACDVSMRVVVGEPPEARVVTGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSHSVTAYMVSAAGLGLVAIYFATQVVFDKNDLAKYSV", "length": 553 }, "evidence": [ { "id": "E1BMB9", "url": "https://omabrowser.org/oma/group/E1BMB9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JT2-1", "protein_name": "Solute carrier family 45 member 3", "gene_name": "SLC45A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVQRLWVSRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVCVPLLGSASDHWRGRYGRRRPFIWALSLGILLSLFLIPRAGWLAGLLCPDPRPLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAYSVYAFMISLGGCLGYLLPAIDWDTSALAPYLGTQEECLFGLLTLIFLTCVAATLLVAEEAALGPTEPAEGLSAPSLSPHCCPCRARLAFRNLGALLPRLHQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYDEGVRMGSLGLFLQCAISLVFSLVMDRLVQRFGTRAVYLASVAAFPVAAGATCLSHSVAVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDTGGASSEDSLMTSFLPGPKPGAPFPNGHVGAGGSGLLPPPPALCGASACDVSVRVVVGEPTEARVVPGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSQSVTAYMVSAAGLGLVAIYFATQVVFDKSDLAKYSA", "length": 553 }, "evidence": [ { "id": "E1BMB9", "url": "https://omabrowser.org/oma/group/E1BMB9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BMB9", "url": "https://www.uniprot.org/uniprotkb/E1BMB9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of glucose metabolic process", "id": "GO:0010907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010907", "evidence": [ { "database": "UniProtKB", "id": "E1BMB9", "url": "https://www.uniprot.org/uniprotkb/E1BMB9" } ], "pmid": "" }, { "name": "positive regulation of fatty acid biosynthetic process", "id": "GO:0045723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045723", "evidence": [ { "database": "UniProtKB", "id": "E1BMB9", "url": "https://www.uniprot.org/uniprotkb/E1BMB9" } ], "pmid": "" }, { "name": "regulation of oligodendrocyte differentiation", "id": "GO:0048713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048713", "evidence": [ { "database": "UniProtKB", "id": "E1BMB9", "url": "https://www.uniprot.org/uniprotkb/E1BMB9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sucrose:proton symporter activity", "id": "GO:0008506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008506", "evidence": [ { "database": "UniProtKB", "id": "E1BMB9", "url": "https://www.uniprot.org/uniprotkb/E1BMB9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMB9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 550, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMB9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMB9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/E1BMD1" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "E1BMD1", "url": "https://www.uniprot.org/uniprotkb/E1BMD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1260, "end_pos": 1262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1438, "end_pos": 1440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1589, "end_pos": 1591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21100:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BMD9", "url": "https://www.uniprot.org/uniprotkb/E1BMD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMD9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATMKKTAAEDVNITFEDQQKIKKFAQNTSRITELKEEIEVKKKQLQNLEDVCEDIMLADDNFLMTPYHIGDVFINHSQEETQEMLEEAKKNLQEETDALESRMESIQWVLADLKLHAKSGSNITLKLKHFI", "length": 133, "header": "tr|E1BMD9-1|E1BMD9_BOVIN Isoform 1 of Prefoldin subunit 4 OS=Bos taurus OX=9913 GN=LOC101905125 PE=3 SV=3 CANONICAL=E1BMD9-1" }, "isoforms": [ { "isoform_ac": "E1BMD9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD9/entry#E1BMD9-1", "sequence": { "sequence": "MAATMKKTAAEDVNITFEDQQKIKKFAQNTSRITELKEEIEVKKKQLQNLEDVCEDIMLADDNFLMTPYHIGDVFINHSQEETQEMLEEAKKNLQEETDALESRMESIQWVLADLKLHAKSGSNITLKLKHFI", "length": 133, "header": "tr|E1BMD9-1|E1BMD9_BOVIN Isoform 1 of Prefoldin subunit 4 OS=Bos taurus OX=9913 GN=LOC101905125 PE=3 SV=3 CANONICAL=E1BMD9-1" }, "locus": { "chromosome": "1", "start_pos": 132548300, "end_pos": 132547747, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021695.5", "url": "https://www.ensembl.org/id/ENSBTAT00000021695.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021695.5", "url": "https://www.ensembl.org/id/ENSBTAP00000021695.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BMD9", "url": "https://www.uniprot.org/uniprotkb/E1BMD9" } ], "pmid": "" }, { "name": "prefoldin complex", "id": "GO:0016272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016272", "evidence": [ { "database": "UniProtKB", "id": "E1BMD9", "url": "https://www.uniprot.org/uniprotkb/E1BMD9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "E1BMD9", "url": "https://www.uniprot.org/uniprotkb/E1BMD9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "E1BMD9", "url": "https://www.uniprot.org/uniprotkb/E1BMD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMD9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 133, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMD9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMD9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 14, "end_pos": 16 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMF1-1", "uniprot_ac": "E1BMF1", "uniprot_id": "E1BMF1_BOVIN", "mass": { "chemical_mass": 67529.0, "monoisotopic_mass": 67529.0 }, "refseq": { "ac": "NP_001180146", "name": "transmembrane 9 superfamily member 3 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180146" }, "gene_names": [ { "name": "TM9SF3", "type": "recommended", "evidence": [ { "id": "E1BMF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMF1" } ] }, { "name": "TM9SF3", "type": "synonym", "evidence": [ { "id": "NP_001180146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180146" } ] } ], "protein_names": [ { "name": "Transmembrane 9 superfamily member", "type": "recommended", "evidence": [ { "id": "E1BMF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMF1/entry#names_and_taxonomy" } ] }, { "name": "transmembrane 9 superfamily member 3 precursor", "type": "synonym", "evidence": [ { "id": "NP_001180146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180146" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMF1", "url": "https://www.uniprot.org/uniprotkb/E1BMF1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TM9SF3", "url": "https://www.uniprot.org/uniprotkb/E1BMF1", "locus": { "chromosome": "26", "start_pos": 17851539, "end_pos": 17912665, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016298", "url": "https://www.ensembl.org/id/ENSBTAG00000016298" } ] } } ], "crossref": [ { "id": "E1BMF1", "url": "https://alphafold.ebi.ac.uk/entry/E1BMF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016298", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016298", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "614147", "url": "https://www.ncbi.nlm.nih.gov/gene/614147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614147", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614147", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAPCRVN", "url": "https://omabrowser.org/oma/group/DAPCRVN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMF1", "url": "https://www.orthodb.org/?gene=E1BMF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10766", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10766:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02990", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02990", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180146", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BMF1", "url": "https://www.uniprot.org/uniprotkb/E1BMF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMF1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPLPGAPGVAAAAALLLLLLPRARADEHEHTYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPGTYCEIDLDKEKRDAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGFNGNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIIVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "length": 587, "header": "tr|E1BMF1-1|E1BMF1_BOVIN Isoform 1 of Transmembrane 9 superfamily member OS=Bos taurus OX=9913 GN=TM9SF3 PE=3 SV=1 CANONICAL=E1BMF1-1" }, "isoforms": [ { "isoform_ac": "E1BMF1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMF1/entry#E1BMF1-1", "sequence": { "sequence": "MRPLPGAPGVAAAAALLLLLLPRARADEHEHTYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPGTYCEIDLDKEKRDAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGFNGNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIIVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "length": 587, "header": "tr|E1BMF1-1|E1BMF1_BOVIN Isoform 1 of Transmembrane 9 superfamily member OS=Bos taurus OX=9913 GN=TM9SF3 PE=3 SV=1 CANONICAL=E1BMF1-1" }, "locus": { "chromosome": "26", "start_pos": 17912497, "end_pos": 17854892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021686.6", "url": "https://www.ensembl.org/id/ENSBTAT00000021686.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021686.5", "url": "https://www.ensembl.org/id/ENSBTAP00000021686.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614147", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614147", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUD8-1", "protein_name": "Transmembrane 9 superfamily member", "gene_name": "Tm9sf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGDPGACQPGNTHHFTAGSDFSLPFSLSPEPDLNRGVGTALGKRRCEQLTRGQYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPGTYCEIDLDKEKRDAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGFNGNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIIVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "length": 609 }, "evidence": [ { "id": "E1BMF1", "url": "https://omabrowser.org/oma/group/E1BMF1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q940G0-1", "protein_name": "Transmembrane 9 superfamily member 1", "gene_name": "TMN1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPSSSSAAVLVFLLLVSLLTPTFASDSDHKYQAEEQVTLWVNKVGPYNNPQETYNYYSLPFCRPSGNNVHKWGGLGEVLGGNELIDSEIAIKFMKNVERSVICPLELDEAKVKHFKDAIESSYWFEFFMDDLPLWGFVGELHPDKNSENGKHVLYTHKNIVVKYNKDQIIHVNLTQDNPRPLEAGKKMDLTYSVQWIPTNVTFARRFDVYLDYPFFEHQIHWFSIFNSFMMVIFLTGLVSMILMRTLRNDYAKYAREDDDLESLERDVSEESGWKLVHGDVFRPASSLVLLSAVVGTGAQLALLVLLVILMAIVGTLYVGRGAIVTTFIVCYALTSFVSGYVSGGMYSRSGGKHWIKCMVLTASLFPFLCFGIGFLLNTIAIFYGSLAAIPFGTMVVVFVIWGFISFPLALLGTVVGRNWSGAPNNPCRVKTIPRPIPEKKWYLTPSVVSLMGGLLPFGSIFIEMYFVFTSFWNYKVYYVYGFMLLVFVILVIVTVCVTIVGTYFLLNAENYHWQWTSFFSAASTAVYVYLYSIYYYYVKTKMSGFFQTSFYFGYTMMFCLGLGILCGAVGYLGSNLFVRRIYRNIKCD", "length": 589 }, "evidence": [ { "id": "E1BMF1", "url": "https://omabrowser.org/oma/group/E1BMF1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9ET30-1", "protein_name": "Transmembrane 9 superfamily member 3", "gene_name": "Tm9sf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPLPGAPGVAAAAALLLLLLPRARSDEHEHTYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPGTYCEIDLDKEKRDAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGFNGNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIIVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "length": 587 }, "evidence": [ { "id": "E1BMF1", "url": "https://omabrowser.org/oma/group/E1BMF1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HD45-1", "protein_name": "Transmembrane 9 superfamily member 3", "gene_name": "TM9SF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPLPGALGVAAAAALWLLLLLLPRTRADEHEHTYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPATYCEIDLDKEKRDAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGFNGNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIIVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "length": 589 }, "evidence": [ { "id": "E1BMF1", "url": "https://omabrowser.org/oma/group/E1BMF1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VRN1-1", "protein_name": "Transmembrane 9 superfamily member", "gene_name": "TM9SF3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGSSATQTTVPFRAICLCLLIASCYVSLSQADEHNHKYNDREEVVLWMNTVGPYHNRQETYAYFSLPFCSGQKSSISHYHETLSEALQGVELEFSGYEMEFKSDAPKSVICMVTLQEESAKAFTYAVKNEYWYQMYIDGLPIWGKVGERDERDGKYYIFTHKKFDIGYNGQQIVDITLTTEGREELKPGSHINFSYEVNWKPSKVEFKNRFDKYLDPNFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKDEEIDDMERDLGDEYGWKQVHGDVFRSPPNTLLFSALVGAGYQLISVVFCVIMFAIVGELYTERGSMLSTAIFVYAATSPINGYFGGSLYARLGGRMWIRQMLVSAFTVPVAVCGTAFLINFIAIGYHASRAIPFGTMVAVTCICLFVILPLTLVGTVVGRNLDGQPDFPCRVNAVPRPIPEKKWYMEPLIIVLLGGVLPFGSIFIEMYFIFTSFWAYKIYYVYGFMLLVFSILTVVTVCVTIVCTYFLLNAEDYRWQWTSFMAAGSTSIYVYAYSFYYFFFKTKMFGLFQTAFYFGYMALFSGALGIICGTVGYVGTNLFVRKIYSNVKID", "length": 592 }, "evidence": [ { "id": "E1BMF1", "url": "https://omabrowser.org/oma/group/E1BMF1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BMF1", "url": "https://www.uniprot.org/uniprotkb/E1BMF1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "E1BMF1", "url": "https://www.uniprot.org/uniprotkb/E1BMF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMF1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 587, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMF1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMF1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 417, "end_pos": 419 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMF9-1", "uniprot_ac": "E1BMF9", "uniprot_id": "E1BMF9_BOVIN", "mass": { "chemical_mass": 117724.0, "monoisotopic_mass": 117724.0 }, "refseq": {}, "gene_names": [ { "name": "LLGL1", "type": "recommended", "evidence": [ { "id": "E1BMF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ] } ], "protein_names": [ { "name": "LLGL scribble cell polarity complex component 1", "type": "synonym", "evidence": [ { "id": "E1BMF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMF9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LLGL1", "url": "https://www.uniprot.org/uniprotkb/E1BMF9", "locus": { "chromosome": "19", "start_pos": 34398904, "end_pos": 34414514, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004635", "url": "https://www.ensembl.org/id/ENSBTAG00000004635" } ] } } ], "crossref": [ { "id": "E1BMF9", "url": "https://alphafold.ebi.ac.uk/entry/E1BMF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004635", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004635", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000664", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000664", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BMF9", "url": "https://www.orthodb.org/?gene=E1BMF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10241:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10241:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NS55", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS55-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMF9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RLJ0", "url": "https://www.uniprot.org/uniprotkb/F6RLJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RLJ0-1", "url": "https://www.uniprot.org/uniprotkb/F6RLJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQEFPRGWGRRRAFPTDHPAGTGAWRGRYSGPLGQGADPQREKLKQELFAFHKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAATVTQMHFLPGQGRVLTLLDDDSLHLWEIVHHDGCAHLEEAIHFQAPSRPGFDGASGLPSLAHITVVLLVAAGDMAALGTEGGSIFFLDVPTLTLLEGQTLGPDEVLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQAARCAERIFLGNQQLESVCWERSGHTVVSSHSDGSYAIWAADTGDSPTAQPTVATTPYGPFPCKAINKVLWRSCASGEHFVIFSGGMPRASYGDRHCVSVLQAETLVTLDFTSRVIDFFTVHSTRPEDEFDEPQALAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVANVPAKLWARIVSAGEQQSPQPASGASSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLCTAGLFQTDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLVLELSDTPAEQTVGVASLDLLQDREGFTWKGHERLSPRLGPLPWPAGFQPRALVQCLPPAAVTAVTLHAEWGLVAFGTSHGFGLFDYLRRSPVLARCTLHPSDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRASGKKRTVAGSKLQEANAQLAEQAGPQDVEVTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDAAHHGPTMWAGTNSGSVFAYALEVPAAVAGGEKRPERAVEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFASVACEDYTETCLACLTNLGDVHVFSVPGLRPQVHYACIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDVRWPRGATHISHRSRESPKLSQANGTPGIILAPQSCDGSPDPICKEADTPEPPEAMLSPMSIDSATSADTTLDTTGDMTVEDVKDFLGSSEESEKNLRNLSEEEARACAILIK", "length": 1088, "header": "tr|E1BMF9-1|E1BMF9_BOVIN Isoform 1 of LLGL scribble cell polarity complex component 1 OS=Bos taurus OX=9913 GN=LLGL1 PE=3 SV=3 CANONICAL=E1BMF9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NS55-1", "url": "https://www.uniprot.org/uniprotkb/E1BMF9/entry#A0ABI0NS55-1", "sequence": { "sequence": "MMKFRFRRQGADPQREKLKQELFAFHKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAATVTQMHFLPGQGRVLTLLDDDSLHLWEIVHHDGCAHLEEAIHFQAPSRPGFDGASGLPSLAHITVVLLVAAGDMAALGTEGGSIFFLDVPTLTLLEGQTLGPDEVLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQAARCAERIFLGNQQLESVCWERSGHTVVSSHSDGSYAIWAADTGDSPTAQPTVATTPYGPFPCKAINKVLWRSCASGEHFVIFSGGMPRASYGDRHCVSVLQAETLVTLDFTSRVIDFFTVHSTRPEDEFDEPQALAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVANVPAKLWARIVSAGEQQSPQPASGASSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLCTAGLFQTDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLVLELSDTPAEQTVGVASLDLLQDREGFTWKGHERLSPRLGPLPWPAGFQPRALVQCLPPAAVTAVTLHAEWGLVAFGTSHGFGLFDYLRRSPVLARCTLHPSDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRASGKKRTVAGSKLQEANAQLAEQAGPQDVEVTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDAAHHGPTMWAGTNSGSVFAYALEVPAAVAGGEKRPERAVEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFASVACEDYTETCLACLTNLGDVHVFSVPGLRPQVHYACIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDVRWPRGATHIRHPRAT", "length": 965, "header": "tr|A0ABI0NS55-1|A0ABI0NS55_BOVIN Computationally mapped isoform of LLGL scribble cell polarity complex component 1 OS=Bos taurus OX=9913 GN=LLGL1 PE=3 SV=1 CANONICAL=E1BMF9-1" }, "locus": { "chromosome": "19", "start_pos": 34413685, "end_pos": 34400016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149504.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149504.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105632.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105632.1" } ] } }, { "isoform_ac": "E1BMF9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMF9/entry#E1BMF9-1", "sequence": { "sequence": "MQEFPRGWGRRRAFPTDHPAGTGAWRGRYSGPLGQGADPQREKLKQELFAFHKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAATVTQMHFLPGQGRVLTLLDDDSLHLWEIVHHDGCAHLEEAIHFQAPSRPGFDGASGLPSLAHITVVLLVAAGDMAALGTEGGSIFFLDVPTLTLLEGQTLGPDEVLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQAARCAERIFLGNQQLESVCWERSGHTVVSSHSDGSYAIWAADTGDSPTAQPTVATTPYGPFPCKAINKVLWRSCASGEHFVIFSGGMPRASYGDRHCVSVLQAETLVTLDFTSRVIDFFTVHSTRPEDEFDEPQALAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVANVPAKLWARIVSAGEQQSPQPASGASSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLCTAGLFQTDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLVLELSDTPAEQTVGVASLDLLQDREGFTWKGHERLSPRLGPLPWPAGFQPRALVQCLPPAAVTAVTLHAEWGLVAFGTSHGFGLFDYLRRSPVLARCTLHPSDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRASGKKRTVAGSKLQEANAQLAEQAGPQDVEVTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDAAHHGPTMWAGTNSGSVFAYALEVPAAVAGGEKRPERAVEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFASVACEDYTETCLACLTNLGDVHVFSVPGLRPQVHYACIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDVRWPRGATHISHRSRESPKLSQANGTPGIILAPQSCDGSPDPICKEADTPEPPEAMLSPMSIDSATSADTTLDTTGDMTVEDVKDFLGSSEESEKNLRNLSEEEARACAILIK", "length": 1088, "header": "tr|E1BMF9-1|E1BMF9_BOVIN Isoform 1 of LLGL scribble cell polarity complex component 1 OS=Bos taurus OX=9913 GN=LLGL1 PE=3 SV=3 CANONICAL=E1BMF9-1" }, "locus": { "chromosome": "19", "start_pos": 34414315, "end_pos": 34399692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043699.4", "url": "https://www.ensembl.org/id/ENSBTAT00000043699.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041252.4", "url": "https://www.ensembl.org/id/ENSBTAP00000041252.4" } ] } }, { "isoform_ac": "F6RLJ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BMF9/entry#F6RLJ0-1", "sequence": { "sequence": "MMKFRFRRQGADPQREKLKQELFAFHKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAATVTQMHFLPGQGRVLTLLDDDSLHLWEIVHHDGCAHLEEAIHFQAPSRPGFDGASGLPSLAHITVVLLVAAGDMAALGTEGGSIFFLDVPTLTLLEGQTLGPDEVLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQAARCAERIFLGNQQLESVCWERSGHTVVSSHSDGSYAIWAADTGDSPTAQPTVATTPYGPFPCKAINKVLWRSCASGEHFVIFSGGMPRASYGDRHCVSVLQAETLVTLDFTSRVIDFFTVHSTRPEDEFDEPQALAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVANVPAKLWARIVSAGEQQSPQPASGASWWGGALGLTPPLRSHEDGTVRFWDASGVALRPLYKLCTAGLFQTDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLVLELSDTPAEQTVGVASLDLLQDREGFTWKGHERLSPRLGPLPWPAGFQPRALVQCLPPAAVTAVTLHAEWGLVAFGTSHGFGLFDYLRRSPVLARCTLHPSDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRASGKKRTVAGSKLQEANAQLAEQAGPQDVEVTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDAAHHGPTMWAGTNSGSVFAYALEVPAAVAGGEKRPERAVEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFASVACEDYTETCLACLTNLGDVHVFSVPGLRPQVHYACIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDVRWPRGATHIRSRESPKLSQANGTPGIILAPQSCDGSPDPICKEADTPEPPEAMLSPMSIDSATSADTTLDTTGDMTVEDVKDFLG", "length": 1026, "header": "tr|F6RLJ0-1|E1BMF9_BOVIN Computationally mapped isoform of LLGL scribble cell polarity complex component 1 OS=Bos taurus OX=9913 GN=LLGL1 PE=3 SV=2 CANONICAL=E1BMF9-1" }, "locus": { "chromosome": "19", "start_pos": 34413685, "end_pos": 34399910, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006080.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006080.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006080.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006080.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "establishment of spindle orientation", "id": "GO:0051294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051294", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" }, { "name": "regulation of establishment or maintenance of cell polarity", "id": "GO:0032878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032878", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" }, { "name": "regulation of Notch signaling pathway", "id": "GO:0008593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008593", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "myosin II binding", "id": "GO:0045159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045159", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "E1BMF9", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1074, "end_pos": 1076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMF9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1088, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMF9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMF9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMF9" }, { "id": "PF08366", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08366" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lethal giant larvae homologue 2", "eco_id": "ECO_0000259", "start_pos": 306, "end_pos": 406, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1074, "end_pos": 1076 }, { "start_pos": 966, "end_pos": 968 }, { "start_pos": 999, "end_pos": 1001 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMH2-1", "uniprot_ac": "E1BMH2", "uniprot_id": "E1BMH2_BOVIN", "mass": { "chemical_mass": 150128.0, "monoisotopic_mass": 150128.0 }, "refseq": { "ac": "XP_010807241", "name": "capping protein, Arp2/3 and myosin-I linker protein 3 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807241" }, "gene_names": [ { "name": "CARMIL3", "type": "recommended", "evidence": [ { "id": "E1BMH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMH2" } ] }, { "name": "CARMIL3", "type": "synonym", "evidence": [ { "id": "XP_010807241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807241" } ] } ], "protein_names": [ { "name": "Capping protein, Arp2/3 and myosin-I linker protein 3", "type": "recommended", "evidence": [ { "id": "E1BMH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMH2/entry#names_and_taxonomy" } ] }, { "name": "Capping protein regulator and myosin 1 linker protein 3", "type": "synonym", "evidence": [ { "id": "E1BMH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMH2/entry#names_and_taxonomy" } ] }, { "name": "Leucine-rich repeat-containing protein 16B", "type": "synonym", "evidence": [ { "id": "E1BMH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMH2/entry#names_and_taxonomy" } ] }, { "name": "capping protein, Arp2/3 and myosin-I linker protein 3 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_010807241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807241" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMH2", "url": "https://www.uniprot.org/uniprotkb/E1BMH2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CARMIL3", "url": "https://www.uniprot.org/uniprotkb/E1BMH2", "locus": { "chromosome": "10", "start_pos": 21070624, "end_pos": 21087501, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015208", "url": "https://www.ensembl.org/id/ENSBTAG00000015208" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015208", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015208", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "517186", "url": "https://www.ncbi.nlm.nih.gov/gene/517186", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BMH2", "url": "https://www.orthodb.org/?gene=E1BMH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24112:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24112:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17888", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17888", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010807241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BMH2", "url": "https://www.uniprot.org/uniprotkb/E1BMH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMH2-1", "url": "https://www.uniprot.org/uniprotkb/E1BMH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKSSAELTRELQDSIRRCLSQGAVLQQHRVKLETKPKKFEDRVLALTSWRLHLFPLKVPAKVESSFNVLEIRAFNTLSQNQILVETERGMVSMRLPSAESVDQVTRHVSSALSKVCPGPGSLIRRGNADTPDGPRDTSPNSETSTSTTHSVCGGFSETYAALCDYNGLHCREEVQWDVDTIYHAEDNREFNLLDFSHLESRDLALMVAALAYNQWFTKLYCKDLRLGSEVLEQVLHTLSKSGSLEELVLDNAGLKTDFVQKLAGVFGENGSCVLHALTLSHNPIEDKGFLSLSQQLLCFPTGLTKLCLAKTAISPRGLQALGQTFGANPAFASSLRYLDLSKNPGLLATDEANALYSFLAQPNALVHLDLAGTDCTIDSLLGALLHGCCSHLTYLNLARNSCSHRKGREAPPAFKQFFSSAYTLSHVNLSATRLPLEALRALLQGLSLNSHLSDLHLDLSSCELRSAGAQALQEQLGAVTCVGSLDLSDNGFDSDLLTLVPALGKNKSLKHLFLGKNFNVKAKTLEEILHKLVQLIQEEDCSLQSLSVADSRLKLRTSILINALGSNTCLAKVDLSGNGMEDIGAKMLSKALQINSSLRTILWDRNNTSALGFLDIARALESNHTLRFMSFPVSDISQAYRSAPERTEDVWQKIQWCLVRNNHSQTCPQEQAFRLQQGLVTSSAEQMLQRLCGRVQEEVRALRLCPLEPVQDELLYARDLIKDAKNSRALFPSLYELGHMLANDGPVRQRLESVASEVSKAVDKELQVILESMVSLTQELCPVAMRVAEGHNKMLSNVAERVTVPRNFIRGALLEQAGQDIQNKLDEVKLSVVTYLTNSIVDEILQELYHSHKSLARHLAQLRTLSDPPGGPGQGQDLSSRGRGRNHDHEETTDDELGTNIDTMAIKKQKRCRKIRPVSAFISGSPQDMESQLGSLGIPPGWFSGLGSSQPAASGSWEGLSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSQAPVPGTRQENGMATRLDEGLEDFFSRRVMDESSSYPRTLRTLRPGLSEPPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPTFGGSRGPSFRRKTGTEGAEPGEGGQAPGAAQQPRVHGVALPGLGRAKGWSFDGKREGTGPDLEGSVQAWQKRRSSDDAGPGAWKPPPPAQSTKPSFSAMRRAEATWHIAEESAPNHGCQSPSPASQDGEEEKEGAVFPERTVSTRNAKLQDPPLTLKPPKPVAVPRGRRPPQEPGGREEVETGGAAPGMNKPRLQLGSQQDQEEPEIQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRQPPDPTAGTSEPGTD", 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"MAKSSAELTRELQDSIRRCLSQGAVLQQHRVKLETKPKKFEDRVLALTSWRLHLFPLKVPAKVESSFNVLEIRAFNTLSQNQILVETERGMVSMRLPSAESVDQVTRHVSSALSKVCPGPGSLIRRGNADTPDGPRDTSPNSETSTSTTHSVCGGFSETYAALCDYNGLHCREEVQWDVDTIYHAEDNREFNLLDFSHLESRDLALMVAALAYNQWFTKLYCKDLRLGSEVLEQVLHTLSKSGSLEELVLDNAGLKTDFVQKLAGVFGENGSCVLHALTLSHNPIEDKGFLSLSQQLLCFPTGLTKLCLAKTAISPRGLQALGQTFGANPAFASSLRYLDLSKNPGLLATDEANALYSFLAQPNALVHLDLAGTDCTIDSLLGALLHGCCSHLTYLNLARNSCSHRKGREAPPAFKQFFSSAYTLSHVNLSATRLPLEALRALLQGLSLNSHLSDLHLDLSSCELRSAGAQALQEQLGAVTCVGSLDLSDNGFDSDLLTLVPALGKNKSLKHLFLGKNFNVKAKTLEEILHKLVQLIQEEDCSLQSLSVADSRLKLRTSILINALGSNTCLAKVDLSGNGMEDIGAKMLSKALQINSSLRTILWDRNNTSALGFLDIARALESNHTLRFMSFPVSDISQAYRSAPERTEDVWQKIQWCLVRNNHSQTCPQEQAFRLQQGLVTSSAEQMLQRLCGRVQEEVRALRLCPLEPVQDELLYARDLIKDAKNSRALFPSLYELGHMLANDGPVRQRLESVASEVSKAVDKELQVILESMVSLTQELCPVAMRVAEGHNKMLSNVAERVTVPRNFIRGALLEQAGQDIQNKLDEVKLSVVTYLTNSIVDEILQELYHSHKSLARHLAQLRTLSDPPGGPGQGQDLSSRGRGRNHDHEETTDDELGTNIDTMAIKKQKRCRKIRPVSAFISGSPQDMESQLGSLGIPPGWFSGLGSSQPAASGSWEGLSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSQAPVPGTRQENGMATRLDEGLEDFFSRRVMDESSSYPRTLRTLRPGLSEPPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPTFGGSRGPSFRRKTGTEGAEPGEGGQAPGAAQQPRVHGVALPGLGRAKGWSFDGKREGTGPDLEGSVQAWQKRRSSDDAGPGAWKPPPPAQSTKPSFSAMRRAEATWHIAEESAPNHGCQSPSPASQDGEEEKEGAVFPERTVSTRNAKLQDPPLTLKPPKPVAVPRGRRPPQEPGGREEVETGGAAPGMNKPRLQLGSQQDQEEPEIQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRQPPDPTAGTSEPGTD", "length": 1374, "header": "tr|E1BMH2-1|E1BMH2_BOVIN Isoform 1 of Capping protein, Arp2/3 and myosin-I linker protein 3 OS=Bos taurus OX=9913 GN=CARMIL3 PE=3 SV=4 CANONICAL=E1BMH2-1" }, "locus": { "chromosome": "10", "start_pos": 21087370, "end_pos": 21070902, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061091.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061091.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053203.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053203.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1089, "start_aa": "Thr", "end_pos": 1089, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1089", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1365, "start_aa": "Thr", "end_pos": 1365, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1365", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BMH2", "url": 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"MIANLVSMETDLAMNIGLDTSGEAPTALPPMPNVTETLWDLAMVVSQSTQWPLLDTGSSENFSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVICYPYPEEWGINYAKSMVLLHFLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVRQVRARRKVAVTVLAFVVIFGICFLPYHVFFLWFYFWPTAQDDYNAFWHVLRIVAYCMSFANSCANPVALYFVSGAFRKHFNRYLFCRGASGRRKKRGQHDTFCMHRDTSLTSTASKRFQSRHSCYQSTIRSCRLQETTITTLPNGGNQNGANISAVELALPVLQAPGHNEAHAPPSYGFLPLNEIVQQTRSSPAKFQESLLN", "length": 499 }, "evidence": [ { "id": "E1BMI3", "url": "https://omabrowser.org/oma/group/E1BMI3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "G3H6K6-1", "protein_name": "Bombesin receptor subtype-3", "gene_name": "Brs3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQRQPQSPNQTFFAITNDTESSSSVVSNDTTHKGWTGDNSPGIEALCAIYITYTVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDMLLLLTCVPVDATHYLAEGWLFGKIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCAKAGGIWIMSMIFALPEAIFSDVYTFRDPNRNVTFESCNSYPVSERLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIAKTVLVLVALFAVCWLPNHLLYLYHSFTYKSYDAPTAVPFIITIFSRVLAFSNSCVNPFALYWLSKSFQEHFKAELCCFKAEQPEPPLGDTPLTNLTVMGRVPGTGSTHVSEISVTLFSGCSVKKGEDKV", "length": 399 }, "evidence": [ { "id": "E1BMI3", "url": "https://omabrowser.org/oma/group/E1BMI3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O54798-1", "protein_name": "Bombesin receptor subtype-3", "gene_name": "Brs3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQRQSQSPNQTLISITNDTETSSSVVSNDTTHKGWTGDNSPGIEALCAIYITYAGIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGKVGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPPNAILKTCAKAGGIWIVSMIFALPEAIFSNVYTFQDPNRNVTFESCNSYPISERLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIAKTVLVLVALFALCWLPNHLLYLYHSFTYESYANHSDVPFVIIIFSRVLAFSNSCVNPFALYWLSKTFQQHFKAQLCCLKAEQPEPPLGDIPLNNLTVMGRVPATGSAHVSEISVTLFSGSSAKKGEDKV", "length": 399 }, "evidence": [ { "id": "E1BMI3", "url": "https://omabrowser.org/oma/group/E1BMI3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P32247-1", "protein_name": "Bombesin receptor subtype-3", "gene_name": "BRS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADTSLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF", "length": 399 }, "evidence": [ { "id": "E1BMI3", "url": "https://omabrowser.org/oma/group/E1BMI3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K418-1", "protein_name": "Bombesin receptor subtype-3", "gene_name": "Brs3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQRQPQSPNQTLISITNDTETSSSAVSNDTTPKGWTGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGKVGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCAKAGGIWIMAMIFALPEAIFSNVYTFQDPNRNVTFESCNSYPISERLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIAKTVLVLVALFALCWLPNHLLYLYHSFTYESYAEPSDVPFVVTIFSRVLAFSNSCVNPFALYWLSKTFQKHFKAQLCCFKAEQPEPPLGDTPLNNLTVMGRVPATGSAHVSEISVTLFSGSTAKKGEDKV", "length": 399 }, "evidence": [ { "id": "E1BMI3", "url": "https://omabrowser.org/oma/group/E1BMI3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BMI3", "url": "https://www.uniprot.org/uniprotkb/E1BMI3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "E1BMI3", "url": "https://www.uniprot.org/uniprotkb/E1BMI3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "neuropeptide receptor activity", "id": "GO:0008188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008188", "evidence": [ { "database": "UniProtKB", "id": "E1BMI3", "url": "https://www.uniprot.org/uniprotkb/E1BMI3" } ], "pmid": "" }, { "name": "bombesin receptor activity", "id": "GO:0004946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004946", "evidence": [ { "database": "UniProtKB", "id": "E1BMI3", "url": "https://www.uniprot.org/uniprotkb/E1BMI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 330, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 18, "end_pos": 20 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 300, "end_pos": 302 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMI6-1", "uniprot_ac": "E1BMI6", "uniprot_id": "E1BMI6_BOVIN", "mass": { "chemical_mass": 62066.0, "monoisotopic_mass": 62066.0 }, "refseq": {}, "gene_names": [ { "name": "GNL3", "type": "recommended", "evidence": [ { "id": "E1BMI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI6" } ] } ], "protein_names": [ { "name": "Guanine nucleotide-binding protein-like 3", "type": "recommended", "evidence": [ { "id": "E1BMI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI6/entry#names_and_taxonomy" } ] }, { "name": "Nucleolar GTP-binding protein 3", "type": "synonym", "evidence": [ { "id": "E1BMI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI6/entry#names_and_taxonomy" } ] }, { "name": "Nucleostemin", "type": "synonym", "evidence": [ { "id": "E1BMI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMI6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.", "evidence": [ { "database": "UniProtKB", "id": "E1BMI6", "url": "https://www.uniprot.org/uniprotkb/E1BMI6#function" }, { "database": "UniProtKB", "id": "ARBA00055611", "url": "https://www.uniprot.org/uniprotkb/ARBA00055611#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMI6", "url": "https://www.uniprot.org/uniprotkb/E1BMI6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GNL3", "url": "https://www.uniprot.org/uniprotkb/E1BMI6", "locus": { "chromosome": "22", "start_pos": 48169643, "end_pos": 48175948, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014549", "url": "https://www.ensembl.org/id/ENSBTAG00000014549" } ] } } ], "crossref": [ { "id": "E1BMI6", "url": "https://alphafold.ebi.ac.uk/entry/E1BMI6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014549", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014549", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04178", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04178", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BMI6", "url": "https://www.orthodb.org/?gene=E1BMI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11089", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11089", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11089:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11089:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BMI6", "url": "https://www.uniprot.org/uniprotkb/E1BMI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMI6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGRKKPRKDPGVPNSAPFKEALLREAELRKQQLEELKQQQKLDRQNERNKKRKLETDPDVKLSNTEPVTEELGQRKAKKAKTSKQNPKRLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIIRGGQKKLVLVLNKSDLVPKENLENWLSYLNKELPTVVFKASTQQKDKRKRIKLVKVKKKAALSKSEVCVGKQGLWKLLEGFQKTSGKAIHVGVIGFPNVGKSSVINSLKQEQICSVGVSMGLTRCMQLVPLDKQITIIDSPCFIVSPLNSAPALALRSPASIEVVRPLEAASAILSQADAQQVVLKFTVPVFTNSLEFFTSFAQRRGLHQKGGSPNVEGAAKVLWSEWTGAFLGYYCHPPASWTPPPHFNESIVTDMKWGFDLEELEKNNAHSIQAIKSPHLASSILFQSSGLTNGVIDENDIPEELLKQKKQKQEQESYEYVKMDQGIVDEEGDDESLAMSPAEEACETLSEKSRADKQSAPSFVLDKMTEEEDDVYDFSTDYV", "length": 550, "header": "tr|E1BMI6-1|E1BMI6_BOVIN Isoform 1 of Guanine nucleotide-binding protein-like 3 OS=Bos taurus OX=9913 GN=GNL3 PE=4 SV=3 CANONICAL=E1BMI6-1" }, "isoforms": [ { "isoform_ac": "E1BMI6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMI6/entry#E1BMI6-1", "sequence": { "sequence": "MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGRKKPRKDPGVPNSAPFKEALLREAELRKQQLEELKQQQKLDRQNERNKKRKLETDPDVKLSNTEPVTEELGQRKAKKAKTSKQNPKRLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIIRGGQKKLVLVLNKSDLVPKENLENWLSYLNKELPTVVFKASTQQKDKRKRIKLVKVKKKAALSKSEVCVGKQGLWKLLEGFQKTSGKAIHVGVIGFPNVGKSSVINSLKQEQICSVGVSMGLTRCMQLVPLDKQITIIDSPCFIVSPLNSAPALALRSPASIEVVRPLEAASAILSQADAQQVVLKFTVPVFTNSLEFFTSFAQRRGLHQKGGSPNVEGAAKVLWSEWTGAFLGYYCHPPASWTPPPHFNESIVTDMKWGFDLEELEKNNAHSIQAIKSPHLASSILFQSSGLTNGVIDENDIPEELLKQKKQKQEQESYEYVKMDQGIVDEEGDDESLAMSPAEEACETLSEKSRADKQSAPSFVLDKMTEEEDDVYDFSTDYV", "length": 550, "header": "tr|E1BMI6-1|E1BMI6_BOVIN Isoform 1 of Guanine nucleotide-binding protein-like 3 OS=Bos taurus OX=9913 GN=GNL3 PE=4 SV=3 CANONICAL=E1BMI6-1" }, "locus": { "chromosome": "22", "start_pos": 48175878, "end_pos": 48169662, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019339.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019339.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019339.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019339.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of protein localization to chromosome, telomeric region", "id": "GO:1904816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904816", "evidence": [ { "database": "UniProtKB", "id": "E1BMI6", "url": "https://www.uniprot.org/uniprotkb/E1BMI6" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "E1BMI6", "url": "https://www.uniprot.org/uniprotkb/E1BMI6" } ], "pmid": "" }, { "name": "positive regulation of protein sumoylation", "id": "GO:0033235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033235", "evidence": [ { "database": "UniProtKB", "id": "E1BMI6", "url": "https://www.uniprot.org/uniprotkb/E1BMI6" } ], "pmid": "" }, { "name": "stem cell division", "id": "GO:0017145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017145", "evidence": [ { "database": "UniProtKB", "id": "E1BMI6", "url": "https://www.uniprot.org/uniprotkb/E1BMI6" } ], "pmid": "" }, { "name": "positive regulation of miRNA transcription", "id": "GO:1902895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902895", "evidence": [ { "database": "UniProtKB", "id": "E1BMI6", "url": "https://www.uniprot.org/uniprotkb/E1BMI6" } ], "pmid": "" }, { "name": "positive regulation of telomere maintenance", "id": "GO:0032206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032206", "evidence": [ { "database": "UniProtKB", "id": "E1BMI6", "url": "https://www.uniprot.org/uniprotkb/E1BMI6" } ], "pmid": "" } ] }, { 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"evidence": [ { "id": "E1BML6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BML6" } ] }, { "name": "SLC2A13", "type": "synonym", "evidence": [ { "id": "NP_001179892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179892" } ] } ], "protein_names": [ { "name": "Proton myo-inositol cotransporter", "type": "recommended", "evidence": [ { "id": "E1BML6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BML6/entry#names_and_taxonomy" } ] }, { "name": "H(+)-myo-inositol symporter", "type": "synonym", "evidence": [ { "id": "E1BML6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BML6/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 2 member 13", "type": "synonym", "evidence": [ { "id": "E1BML6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BML6/entry#names_and_taxonomy" } ] }, { "name": "proton myo-inositol cotransporter", "type": "synonym", "evidence": [ { "id": "NP_001179892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179892" } ] } ], "function": [ { "annotation": "H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.", "evidence": [ { "database": "UniProtKB", "id": "E1BML6", "url": "https://www.uniprot.org/uniprotkb/E1BML6#function" }, { "database": "UniProtKB", "id": "ARBA00056971", "url": "https://www.uniprot.org/uniprotkb/ARBA00056971#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BML6", "url": "https://www.uniprot.org/uniprotkb/E1BML6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC2A13", "url": "https://www.uniprot.org/uniprotkb/E1BML6", "locus": { "chromosome": "5", "start_pos": 41332738, "end_pos": 40812649, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000043962", "url": "https://www.ensembl.org/id/ENSBTAG00000043962" } ] } } ], "crossref": [ { "id": "E1BML6", "url": "https://alphafold.ebi.ac.uk/entry/E1BML6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000043962", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000043962", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17360", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17360", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "613556", "url": "https://www.ncbi.nlm.nih.gov/gene/613556", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613556", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613556", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETGWRWM", "url": "https://omabrowser.org/oma/group/ETGWRWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BML6", "url": "https://www.orthodb.org/?gene=E1BML6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48020:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48020:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-429593", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-429593", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179892", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179892", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "60364", "url": "https://www.rhea-db.org/rhea/60364", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BML6", "url": "https://www.uniprot.org/uniprotkb/E1BML6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BML6-1", "url": "https://www.uniprot.org/uniprotkb/E1BML6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRKASENVEYTLRSLSSLMGERRRKQQEPDAASTAGERSLLAAAESSASLQGAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDAMWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFLLSAQVSPPITFKPIPPLGQNTTCTRYSYCNECMLDPDCGFCYQMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEEIFWAYNFCPTPYSWTALLGLILYLIFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFASMGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGASDSDEGRYIEYIRVKGSNYHLSDNDASDVE", "length": 648, "header": "tr|E1BML6-1|E1BML6_BOVIN Isoform 1 of Proton myo-inositol cotransporter OS=Bos taurus OX=9913 GN=SLC2A13 PE=3 SV=1 CANONICAL=E1BML6-1" }, "isoforms": [ { "isoform_ac": "E1BML6-1", "url": "https://www.uniprot.org/uniprotkb/E1BML6/entry#E1BML6-1", "sequence": { "sequence": "MSRKASENVEYTLRSLSSLMGERRRKQQEPDAASTAGERSLLAAAESSASLQGAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDAMWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFLLSAQVSPPITFKPIPPLGQNTTCTRYSYCNECMLDPDCGFCYQMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEEIFWAYNFCPTPYSWTALLGLILYLIFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFASMGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGASDSDEGRYIEYIRVKGSNYHLSDNDASDVE", "length": 648, "header": "tr|E1BML6-1|E1BML6_BOVIN Isoform 1 of Proton myo-inositol cotransporter OS=Bos taurus OX=9913 GN=SLC2A13 PE=3 SV=1 CANONICAL=E1BML6-1" }, "locus": { "chromosome": "5", "start_pos": 41331734, "end_pos": 40812848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061504.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061504.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053626.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053626.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:613556", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613556", "resource": "KEGG Pathway" }, { "id": "R-BTA-429593", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-429593", "resource": "Reactome", "description": "Inositol transporters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XY55-1", "protein_name": "Proton myo-inositol cotransporter", "gene_name": "SLC2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRKAGDNVEYTLRSLSNLMGEKRRRQAEGAAGSGAAAAGERSLIAAESCSSLNSAASGAELERAARRQFQRDETPGFVYVVSVFSALGGFLFGYDTGVVSGALLLLKRELNLDALWQELLVSGTVGAAALSALAGGVLNGLCGRRPCILLASGLFTAGAGVLAAARDKETLLGGRVVVGLGIGVASMTVPVYIAEVAPPHLRGRLVTINTLFITGGQFFASVVDGLFSYLVKDGWRYMLGLSAVPAVIQFFGFLFLPESPRWLIQKGQTQRARRILSQMRGNQAIDEEYDSIKNNIEEEEKEVGAAGPVICRMLTYPPTRRALIVGCGLQMFQQLSGINTVMYYSATILQMSGVEDDRLAIWLAALTAFINFIFTLVGVWLVERMGRRKLTLGSLAGTAVALIILASGFLLSAQVSPRVTLNPPDPSHQNSTCTKYSYCNGCMLDPDCGLCYKLNKSSVVESSCIPVDKHSTMKAAWGRCSNETIFKKEDLFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGVNWVFNVLVSLTFLHTAEYLTYYGAFFLYAGFAGLGLLFIYGCLPETKGKKLEEIESLFESRLCTCGMSDSDEGRYIEYIRVKGSNYHLSDNDASDVE", "length": 646 }, "evidence": [ { "id": "E1BML6", "url": "https://omabrowser.org/oma/group/E1BML6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SHN8-1", "protein_name": "Proton myo-inositol cotransporter", "gene_name": "SLC2A13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKASENVEYTLRSLSSLMGERRRKQQEPDAASAAGERSLLAAAESSASLQGAGAGGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGAFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFLLSAQVSPPITLKPVAPLGQNTTCTRYSYCDECMLDPDCGFCYKMNKSAIIDSSCVPVNKASTNEAAWGRCENETKFKTEEIFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAMGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGASDSDEGRYIEYIRVKGSNYHLSDNDASDVE", "length": 649 }, "evidence": [ { "id": "E1BML6", "url": "https://omabrowser.org/oma/group/E1BML6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P30606-1", "protein_name": "Myo-inositol transporter 2", "gene_name": "ITR2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKNSTAASSRWTKSRLSHFFPSYTNSSGMGAASTDQSSTQGEELHHRKHCEEDNDGQKPKKSPVSTSTMQIKSRQDEDEDDGRIVIKPVNDEDDTSVIITFNQSISPFIITLTFVASISGFMFGYDTGYISSALISINRDLDNKVLTYGEKELITAATSLGALITSVGAGTAADVFGRRPCLMFSNLMFLIGAILQITAHKFWQMAAGRLIMGFGVGIGSLISPLFISEIAPKMIRGRLTVINSLWLTGGQLIAYGCGAGLNHVKNGWRILVGLSLIPTVLQFSFFCFLPDTPRYYVMKGDLKRAKMVLKRSYVNTEDEIIDQKVEELSSLNQSIPGKNPITKFWNMVKELHTVPSNFRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSGTNFVFTLIAFFCIDKIGRRYILLIGLPGMTVALVICAIAFHFLGIKFNGADAVVASDGFSSWGIVIIVFIIVYAAFYALGIGTVPWQQSELFPQNVRGVGTSYATATNWAGSLVIASTFLTMLQNITPTGTFSFFAGVACLSTIFCYFCYPELSGLELEEVQTILKDGFNIKASKALAKKRKQQVAEGAAHHKLKFEPTQEIVES", "length": 609 }, "evidence": [ { "id": "E1BML6", "url": "https://omabrowser.org/oma/group/E1BML6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3UHK1-1", "protein_name": "Proton myo-inositol cotransporter", "gene_name": "Slc2a13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRKASEDVEYTLRSLSSLMGERRRRQPEPGAPGGERSLLAAESAASLQGAELERAARRQFQRDETPAFVYAAAAFSALGGFLFGYDTGVVSGAMLLLRRQMRLGAMWQELLVSGAVGAAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIRNSIEEEEKEATAAGPIICRMLSYPPTRRALVVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFLLSAQVSPRVTFRPTTPSDQNTTCTGYSYCNECMLDPDCGFCYKINGSAVIDSSCVPVNKASTTEAAWGRCDNETKFKAEGAHWAYSFCPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIESLFDHRLCSCGAADSDEGRYIEYIRVKGSNYHLSDNDASDVE", "length": 637 }, "evidence": [ { "id": "E1BML6", "url": "https://omabrowser.org/oma/group/E1BML6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VZR6-1", "protein_name": "Inositol transporter 1", "gene_name": "INT1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTLTIPNAPGSSGYLDMFPERRMSYFGNSYILGLTVTAGIGGLLFGYDTGVISGALLYIKDDFEVVKQSSFLQETIVSMALVGAMIGAAAGGWINDYYGRKKATLFADVVFAAGAIVMAAAPDPYVLISGRLLVGLGVGVASVTAPVYIAEASPSEVRGGLVSTNVLMITGGQFLSYLVNSAFTQVPGTWRWMLGVSGVPAVIQFILMLFMPESPRWLFMKNRKAEAIQVLARTYDISRLEDEIDHLSAAEEEEKQRKRTVGYLDVFRSKELRLAFLAGAGLQAFQQFTGINTVMYYSPTIVQMAGFHSNQLALFLSLIVAAMNAAGTVVGIYFIDHCGRKKLALSSLFGVIISLLILSVSFFKQSETSSDGGLYGWLAVLGLALYIVFFAPGMGPVPWTVNSEIYPQQYRGICGGMSATVNWISNLIVAQTFLTIAEAAGTGMTFLILAGIAVLAVIFVIVFVPETQGLTFSEVEQIWKERAYGNISGWGSSSDSNNMEGLLEQGSQS", "length": 509 }, "evidence": [ { "id": "E1BML6", "url": "https://omabrowser.org/oma/group/E1BML6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q921A2-1", "protein_name": "Proton myo-inositol cotransporter", "gene_name": "Slc2a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRKASEDVEYTLRSLSSLMGERRRRQPEPGAPGGERSLLAAESAASLQGAELERAARRQFQRDETPAFVYAAAAFSALGGFLFGYDTGVVSGAMLLLRRQMRLGAMWQELLVSGAVGAAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIRNSIEEEEKEASAAGPIICRMLSYPPTRRALAVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALTILALGFLLSAQVSPRVTFRPTAPSGQNATCTEYSYCNECMLDPDCGFCYKINSSAVIDSSCVPVNKASTNEAAWGRCENETKFKAEDVHWAYSFCPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIESLFDHRLCTCGTADSDEGRYIEYIRVKGSNYHLSDNDASDVE", "length": 637 }, "evidence": [ { "id": "E1BML6", "url": "https://omabrowser.org/oma/group/E1BML6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96QE2-1", "protein_name": "Proton myo-inositol cotransporter", "gene_name": "SLC2A13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVKGSNYHLSDNDASDVE", "length": 648 }, "evidence": [ { "id": "E1BML6", "url": "https://omabrowser.org/oma/group/E1BML6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "E1BML6", "url": "https://www.uniprot.org/uniprotkb/E1BML6" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "E1BML6", "url": "https://www.uniprot.org/uniprotkb/E1BML6" } ], "pmid": "" }, { "name": "myo-inositol:proton symporter activity", "id": "GO:0005366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005366", "evidence": [ { "database": "UniProtKB", "id": "E1BML6", "url": "https://www.uniprot.org/uniprotkb/E1BML6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "E1BML6", "url": "https://www.uniprot.org/uniprotkb/E1BML6" } ], "pmid": "" }, { "name": "positive regulation of 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"end_pos": 598, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 285, "end_pos": 287 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 458, "end_pos": 460 }, { "start_pos": 485, "end_pos": 487 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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Specifically inhibits transactivation of the nuclear receptor with which it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated transcription complex for NEUROD1. Essential component of the liver circadian clock which via its interaction with NR1D1 and RORG regulates NPAS2-mediated hepatic lipid metabolism. Regulates the circadian expression of cytochrome P450 (CYP) enzymes. Represses: NR5A2 and HNF4A to down-regulate CYP2C38, NFLI3 to up-regulate CYP2A5, BHLHE41/HNF1A axis to up-regulate CYP1A2, CYP2E1 and CYP3A11, and NR1D1 to up-regulate CYP2B10, CYP4A10 and CYP4A14.", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7#function" }, { "database": "UniProtKB", "id": "ARBA00056248", "url": "https://www.uniprot.org/uniprotkb/ARBA00056248#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NR0B2", "url": "https://www.uniprot.org/uniprotkb/E1BML7", "locus": { "chromosome": "2", "start_pos": 126306115, "end_pos": 126303167, "strand": "-", "evidence": [ { "database": 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"https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514770", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514770", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FFRPIVG", "url": "https://omabrowser.org/oma/group/FFRPIVG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BML7", "url": "https://www.orthodb.org/?gene=E1BML7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24081:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24081:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002685805", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685805", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BML7-1", "url": "https://www.uniprot.org/uniprotkb/E1BML7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSQPGPCPCQGAAGHPTILYTLLSPRVRDRPSVAPARGRCLCRQHRPVQLCTPHRTCREALDVLAKTLAFLRNLPSFCQLPHHDRRQLLRGCWGPLFLLGLAQDTVTFQVAEVPMPSILKKILLEKPSNGAGSSQRPDRPQPSLAEVQWLQCCLESFWSLELGPKEYAYLKGTILFNPDVPGLYASSHIGHLQQEAHQALWEVLEPWCPAGQSRLARVLLTASTLKSIPPSLLGDLFLRPVIGDVDIADLLEDMLLLS", "length": 260, "header": "tr|E1BML7-1|E1BML7_BOVIN Isoform 1 of Nuclear receptor subfamily 0 group B member 2 OS=Bos taurus OX=9913 GN=NR0B2 PE=3 SV=1 CANONICAL=E1BML7-1" }, "isoforms": [ { "isoform_ac": "E1BML7-1", "url": "https://www.uniprot.org/uniprotkb/E1BML7/entry#E1BML7-1", "sequence": { "sequence": "MSSSQPGPCPCQGAAGHPTILYTLLSPRVRDRPSVAPARGRCLCRQHRPVQLCTPHRTCREALDVLAKTLAFLRNLPSFCQLPHHDRRQLLRGCWGPLFLLGLAQDTVTFQVAEVPMPSILKKILLEKPSNGAGSSQRPDRPQPSLAEVQWLQCCLESFWSLELGPKEYAYLKGTILFNPDVPGLYASSHIGHLQQEAHQALWEVLEPWCPAGQSRLARVLLTASTLKSIPPSLLGDLFLRPVIGDVDIADLLEDMLLLS", "length": 260, "header": "tr|E1BML7-1|E1BML7_BOVIN Isoform 1 of Nuclear receptor subfamily 0 group B member 2 OS=Bos taurus OX=9913 GN=NR0B2 PE=3 SV=1 CANONICAL=E1BML7-1" }, "locus": { "chromosome": "2", "start_pos": 126305111, "end_pos": 126303366, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019772.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019772.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019772.3", "url": "https://www.ensembl.org/id/ENSBTAP00000019772.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514770", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514770", "resource": "KEGG Pathway" }, { "id": "R-BTA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1STR7-1", "protein_name": "Nuclear receptor subfamily 0 group B member 2", "gene_name": "NR0B2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSRQPGTCPCQSAAGRPTILYALLSPSDRDRPSVPPARSHCLCRQHRPVRLCTPHRTCQEALNVLAKTLAFLRNLPSFCQLPPQDQRQLLRGCWGPLFLLGLAQDIVTFEVAEVPVPSILKKILLEEPSSGAGSGQPLDRPQPSLAAVQWLQCCLESLWSLELGPKEYAYLKGTILFNPDVPGLYASSHIGHLQHEAHQALWEVLEPWCPAGQSRLARVLLAASTLKSIPPTLLGDLFFRPVIGDVDIVGLLEDMLLLS", "length": 260 }, "evidence": [ { "id": "E1BML7", "url": "https://omabrowser.org/oma/group/E1BML7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97947-1", "protein_name": "Nuclear receptor subfamily 0 group B member 2", "gene_name": "Nr0b2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSSQSGVCPCQGSASHPTILYTLLSPGPRTRPMAPASRSHCLCQQHRPVRLCAPHRTCREALDVLGKTVAFLRNLPSFCLLPHEDQRRLLEGCWGPLFLLGLAQDTVTFEVAEAPVPSILKKILLEEPNSGAQGAQPPDPPQPSLAAVQWLQHCLESFWSLELGPKEYAYLKGTILFNPDVPGLHASCHIAHLQQEAHWALCEVLEPWYPASQGRLARILLMASTLKNISCTLLVDLFFRPVIGDVDITELLEDMLLLR", "length": 260 }, "evidence": [ { "id": "E1BML7", "url": "https://omabrowser.org/oma/group/E1BML7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15466-1", "protein_name": "Nuclear receptor subfamily 0 group B member 2", "gene_name": "NR0B2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTSQPGACPCQGAASRPAILYALLSSSLKAVPRPRSRCLCRQHRPVQLCAPHRTCREALDVLAKTVAFLRNLPSFWQLPPQDQRRLLQGCWGPLFLLGLAQDAVTFEVAEAPVPSILKKILLEEPSSSGGSGQLPDRPQPSLAAVQWLQCCLESFWSLELSPKEYACLKGTILFNPDVPGLQAASHIGHLQQEAHWVLCEVLEPWCPAAQGRLTRVLLTASTLKSIPTSLLGDLFFRPIIGDVDIAGLLGDMLLLR", "length": 257 }, "evidence": [ { "id": "E1BML7", "url": "https://omabrowser.org/oma/group/E1BML7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62227-1", "protein_name": "Nuclear receptor subfamily 0 group B member 2", "gene_name": "Nr0b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSGQSGVCPCQGSAGRPTILYALLSPSPRTRPVAPASHSHCLCQQQRPVRLCAPHRTCREALDVLAKTVAFLRNLPSFCHLPHEDQRRLLECCWGPLFLLGLAQDAVTFEVAEAPVPSILKKILLEEASSGTQGAQPSDRPQPSLAAVQWLQRCLESFWSLELGPKEYAYLKGTILFNPDVPGLRASCHIAHLQQEAHWALCEVLEPWYPASQGRLARILLMASTLKNIPGTLLVDLFFRPIMGDVDITELLEDMLLLR", "length": 260 }, "evidence": [ { "id": "E1BML7", "url": "https://omabrowser.org/oma/group/E1BML7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "E1BML7", "url": "https://www.uniprot.org/uniprotkb/E1BML7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BML7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 260, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BML7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BML7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BML7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BML7" }, { "id": "PS51843", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51843" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NR LBD", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 260, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMM8-1", "uniprot_ac": "E1BMM8", "uniprot_id": "E1BMM8_BOVIN", "mass": { "chemical_mass": 85488.0, "monoisotopic_mass": 85488.0 }, "refseq": { "ac": "NP_001192680", "name": "chondroitin sulfate synthase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192680" }, "gene_names": [ { "name": "CHPF", "type": "recommended", "evidence": [ { "id": "E1BMM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMM8" } ] }, { "name": "CHPF", "type": "synonym", "evidence": [ { "id": "NP_001192680", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192680" } ] } ], "protein_names": [ { "name": "Hexosyltransferase", "type": "recommended", "evidence": [ { "id": "E1BMM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMM8/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "E1BMM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMM8/entry#names_and_taxonomy" } ] }, { "name": "chondroitin sulfate synthase 2", "type": "synonym", "evidence": [ { "id": "NP_001192680", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192680" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMM8", "url": "https://www.uniprot.org/uniprotkb/E1BMM8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CHPF", "url": "https://www.uniprot.org/uniprotkb/E1BMM8", "locus": { "chromosome": "2", "start_pos": 107466898, "end_pos": 107472327, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020539", "url": "https://www.ensembl.org/id/ENSBTAG00000020539" } ] } } ], "crossref": [ { "id": "E1BMM8", "url": "https://alphafold.ebi.ac.uk/entry/E1BMM8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020539", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020539", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540002", "url": "https://www.ncbi.nlm.nih.gov/gene/540002", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540002", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540002", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MEGKYCY", "url": "https://omabrowser.org/oma/group/MEGKYCY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMM8", "url": "https://www.orthodb.org/?gene=E1BMM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022870", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192680", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192680", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BMM8", "url": "https://www.uniprot.org/uniprotkb/E1BMM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMM8-1", "url": "https://www.uniprot.org/uniprotkb/E1BMM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGAERERPGAGAGAGENWEPRVLPYHPAQPGQAAKKAVRTRYISTELGIRQKLLVAVLTSQATLPTLGVAVNRTLGHRLERVVFLTGSRGRRAPPGMAVVTLGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDATYTEAHGLARLVGRLSLAAAAHLYLGRPQDFIGGEPAPGRYCHGGFGVLLSRTLLQQLRPHLEACRNDIVSARPDEWLGRCILDATGVSCTGDHEGVHYSYLELSPGEPVQEGDPRFRSALTAHPVHDPVHMYQLHKAFARAELERTYQEIQELQWEIQNTSRLAADGERAAAWPVGIPAPSRPASRFEVLRWDYFTEQHAFSCADGSPRCPLRGADRADVADVLGAALEELNRRYHPALRLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRRPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLAPAFLEAFATAALEPGDAAAALTLLLLYEPRQAQRAAHADVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGPPELGRDTGRFDRQAATETCFYNSDYVAARARLAASSDQEEELMESLDVYELFLRFSSLHVLRAVEPALLQHYRAQTCSARLSEDLYHRCRQSALESLGSRTQLAMLLFEQEQGNST", "length": 775, "header": "tr|E1BMM8-1|E1BMM8_BOVIN Isoform 1 of Hexosyltransferase OS=Bos taurus OX=9913 GN=CHPF PE=3 SV=1 CANONICAL=E1BMM8-1" }, "isoforms": [ { "isoform_ac": "E1BMM8-1", "url": "https://www.uniprot.org/uniprotkb/E1BMM8/entry#E1BMM8-1", "sequence": { "sequence": "MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGAERERPGAGAGAGENWEPRVLPYHPAQPGQAAKKAVRTRYISTELGIRQKLLVAVLTSQATLPTLGVAVNRTLGHRLERVVFLTGSRGRRAPPGMAVVTLGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDATYTEAHGLARLVGRLSLAAAAHLYLGRPQDFIGGEPAPGRYCHGGFGVLLSRTLLQQLRPHLEACRNDIVSARPDEWLGRCILDATGVSCTGDHEGVHYSYLELSPGEPVQEGDPRFRSALTAHPVHDPVHMYQLHKAFARAELERTYQEIQELQWEIQNTSRLAADGERAAAWPVGIPAPSRPASRFEVLRWDYFTEQHAFSCADGSPRCPLRGADRADVADVLGAALEELNRRYHPALRLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRRPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLAPAFLEAFATAALEPGDAAAALTLLLLYEPRQAQRAAHADVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGPPELGRDTGRFDRQAATETCFYNSDYVAARARLAASSDQEEELMESLDVYELFLRFSSLHVLRAVEPALLQHYRAQTCSARLSEDLYHRCRQSALESLGSRTQLAMLLFEQEQGNST", "length": 775, "header": "tr|E1BMM8-1|E1BMM8_BOVIN Isoform 1 of Hexosyltransferase OS=Bos taurus OX=9913 GN=CHPF PE=3 SV=1 CANONICAL=E1BMM8-1" }, "locus": { "chromosome": "2", "start_pos": 107472033, "end_pos": 107467343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027366.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027366.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027366.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027366.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:540002", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540002", "resource": "KEGG Pathway" }, { "id": "R-BTA-2022870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "resource": "Reactome", "description": "CS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "F1R7L6-1", "protein_name": "Hexosyltransferase", "gene_name": "chpfa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRFSMLISLLRPIGPVIIGISLGFTLSLLSVSWVEESCDVNAVGDEGIALNQDGSLKGARRPNSISTGNDGEEEEKEDFPPRIIPYKPVKQTQPKKLFRAKYISTELGIRERLFVGIITSKNTINTLGVAVNRTIGHHLDNVVFFTGTRNRKIPHGMNVVTHGDERLIWNMFQTIKYILEHYITEYDWFYLAQDDTYTQADRIKALVGHLSMDRVLYMGSPEEFIGGEMQGRYCYGGFGYLLSRSLLLKLQPFLENCRNDILSARHDEWLGRCIIDYANTNCVEEFEGQRYYYYEMGKNSDPSKEDNVQFKNALTVHPVSDPEQMYRLHKHFTEIELRKTYEEIEKLQAEIRNVSVVAFEGNRSALWPVGINPPFEPKTRFEVLRWDYFTEDQVYSCIDGSPKCELRGVDKLDVADVIETAMGELNKKYKPVLYLKKQQLINGYRRFDPTRGMEYTLDLQLEVVNQKGHSRSITKRVHLVRPLSRIEIIPMPYVTEATRVHIILPVTLQDRDYVHQFLEVYATNAFETSENAILTFLFIYDPIEAQQVNQNDIFSSIKAQISTYEHRYPAVKIPWISVKSESPSQIKFMDIISKKHPVDTLFFIATVKTSISSEFLNRCRMNSINNWQVFFPIHFQYYNPDIAYHNQPLPSALDLVKEAGLFDRSSFTEACFYNSDYMATRTRMSSDVLENEEILENLDIYDMFVKYSGLHVFRAVEPALHQKYSYQTCNPRLSEEIYQRCVQSTLDSLGSRSQLAMLLFEQEQGNST", "length": 768 }, "evidence": [ { "id": "E1BMM8", "url": "https://omabrowser.org/oma/group/E1BMM8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LGX9-1", "protein_name": "Hexosyltransferase", "gene_name": "CHPF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGAEREKPGAGAGAVENWEPRVLPYHPAQPGQAAKKAVRTRYISTELGIRQRLLVAVLTSQATLPTLGVAVNRTLGHRLERVVFLTGSRGRRAPPGMAVVTLGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDATYTEAHGLARLAGHLSLAAAAHLYLGRPQDFISGEPAPGRYCHGGFGVLLSRTLLQQLRPHLEACRNDIVSARPDEWLGRCILDATGVGCTGDHEGVHYSYLELSPGEPVQEGDPRFRSALTAHPVRDPVHMYQLHKAFARAELERTYQEIQELQWEVQNTSRLAADGERAAAWPVGIPAPSRPASRFEVLRWDYFTEQHAFSCADGSPRCPLRGADQADVADVLGAALEELNRRYHPALRLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRRPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLAPGFLEAFATAALEPGDAAAALTLLLLYEPRQAQRAAHADVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGPPELGRDTGRFDRQAATEACFYNSDYVAARARLAAASEQEEELLESLDVYELFLRFSSLHVLRAVEPALLQRYRAQTCSARLSEDLYHRCRQSALESLGSRTQLAMLLFEQEQGNST", "length": 775 }, "evidence": [ { "id": "E1BMM8", "url": "https://omabrowser.org/oma/group/E1BMM8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5XIQ8-1", "protein_name": "Hexosyltransferase", "gene_name": "Chpf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGAERERPGADESWEPRVLPYHPAQPGQATKKAVRTRYISTELGIRQKLLVAVLTSQATLPTLGVAVNRTLGHRLEHVVFLTGARGRRTPSGMAVVALGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDATYTEAHGLDRLTGHLSLASATHLYLGRPQDFIGGETTPGRYCHGGFGVLLSRTLLQQLRPHLESCRNDIVSARPDEWLGRCILDATGIGCTGHHEGMHYNYLELSPGEPVQEGDPRFRSALTAHPVHDPVHMYQLHKAFARAELDRTYQEIQELQWEIQNTSRLAADGERASTWPVGIPAPSRPASRFEVLRWDYFTEQHTFSCADGSPRCLLRGADQADVADVLGTALEELNRRYQPALRLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRWPLTHRVQLLRPLSRVEILPVPYVTEASRVTVLLPLAAAECDLASGFLEAFATAALEPGDAAALTLLLLYEPRQAQRAAHADVFAPVKAHVAELERRFPGARVPWLSVQTSAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGPPELGRDTGHFDRQAASEACFYNSDYVAARGRLVAVSEQEEELLESLDVYELFLRFSSLHVLRAVEPALLQRYRAQPCSARLSEDLYHRCRQSVLEGLGSRTQLAMLLFEQEQGNST", "length": 770 }, "evidence": [ { "id": "E1BMM8", "url": "https://omabrowser.org/oma/group/E1BMM8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IQX7-1", "protein_name": "Chondroitin-polymerizing factor, non-catalytic subunit", "gene_name": "Chpf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGSERERPGAGAGTGESWEPRVLPYHPAQPGQATKKAVRTRYISTELGIRQKLLVAVLTSQATLPTLGVAVNRTLGHRLEHVVFLTGARGRRTPSGMAVVALGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDATYTEAHGLDRLAGHLSLASATHLYLGRPQDFIGGDTTPGRYCHGGFGVLLSRTLLQQLRPHLESCRNDIVSARPDEWLGRCILDATGVGCTGDHEGMHYNYLELSPGEPVQEGDPRFRSALTAHPVRDPVHMYQLHKAFARAELDRTYQEIQELQWEIQNTSRLAADGERASAWPVGIPAPSRPASRFEVLRWDYFTEQYAFSCADGSPRCPLRGADQADVADVLGTALEELNRRYQPALQLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRWPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLASGFLEAFATAALEPGDAAALTLLLLYEPRQAQRAAHSDVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGPPELGRDTGHFDRQAASEACFYNSDYVAARGRLVAASEQEEELLESLDVYELFLRFSNLHVLRAVEPALLQRYRAQPCSARLSEDLYHRCRQSVLEGLGSRTQLAMLLFEQEQGNST", "length": 774 }, "evidence": [ { "id": "E1BMM8", "url": "https://omabrowser.org/oma/group/E1BMM8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZ52-1", "protein_name": "Chondroitin polymerizing factor, non-catalytic subunit", "gene_name": "CHPF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGAEREKPGAGEGAGENWEPRVLPYHPAQPGQAAKKAVRTRYISTELGIRQRLLVAVLTSQTTLPTLGVAVNRTLGHRLERVVFLTGARGRRAPPGMAVVTLGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDTTYTEAHGLARLTGHLSLASAAHLYLGRPQDFIGGEPTPGRYCHGGFGVLLSRMLLQQLRPHLEGCRNDIVSARPDEWLGRCILDATGVGCTGDHEGVHYSHLELSPGEPVQEGDPHFRSALTAHPVRDPVHMYQLHKAFARAELERTYQEIQELQWEIQNTSHLAVDGDQAAAWPVGIPAPSRPASRFEVLRWDYFTEQHAFSCADGSPRCPLRGADRADVADVLGTALEELNRRYHPALRLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRRPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLAPGFLEAFATAALEPGDAAAALTLLLLYEPRQAQRVAHADVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGPPELGRDTGRFDRQAASEACFYNSDYVAARGRLAAASEQEEELLESLDVYELFLHFSSLHVLRAVEPALLQRYRAQTCSARLSEDLYHRCLQSVLEGLGSRTQLAMLLFEQEQGNST", "length": 775 }, "evidence": [ { "id": "E1BMM8", "url": "https://omabrowser.org/oma/group/E1BMM8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BMM8", "url": "https://www.uniprot.org/uniprotkb/E1BMM8" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "E1BMM8", "url": "https://www.uniprot.org/uniprotkb/E1BMM8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "E1BMM8", "url": "https://www.uniprot.org/uniprotkb/E1BMM8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity", "id": "GO:0050510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050510", "evidence": [ { "database": "UniProtKB", "id": "E1BMM8", "url": "https://www.uniprot.org/uniprotkb/E1BMM8" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0047238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047238", "evidence": [ { "database": "UniProtKB", "id": "E1BMM8", "url": "https://www.uniprot.org/uniprotkb/E1BMM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-1971487", "name": "Chondroitin polymerase complex transfers GalNAc to CS chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N783-1", "F6PU96-1", "E1B9D0-1", "E1BMM8-1" ], "evidence": [ { "id": "R-BTA-1971487", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1971487" } ] }, { "id": "R-BTA-1971491", "name": "Chondroitin polymerase complex transfers GlcA to CS chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N783-1", "F6PU96-1", "E1B9D0-1", "E1BMM8-1" ], "evidence": [ { "id": "R-BTA-1971491", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1971491" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1B9D0", "gene_name": "CHPF2", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1B9D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D0" } ] } ] }, { "uniprot_ac": "E1BMM8", "gene_name": "CHPF", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BMM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMM8" } ] } ] }, { "uniprot_ac": "F1N783", "gene_name": "CHSY3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F1N783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N783" } ] } ] }, { "uniprot_ac": "F6PU96", "gene_name": "CHSY1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F6PU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PU96" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMM8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 775, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMM8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMM8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 773, "end_pos": 775 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMN4-1", "uniprot_ac": "E1BMN4", "uniprot_id": "E1BMN4_BOVIN", "mass": { "chemical_mass": 43256.0, "monoisotopic_mass": 43256.0 }, "refseq": { "ac": "NP_001192639", "name": "neuromedin-B receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192639" }, "gene_names": [ { "name": "NMBR", "type": "recommended", "evidence": [ { "id": "E1BMN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ] }, { "name": "NMBR", "type": "synonym", "evidence": [ { "id": "NP_001192639", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192639" } ] } ], "protein_names": [ { "name": "Neuromedin-B receptor", "type": "recommended", "evidence": [ { "id": "E1BMN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN4/entry#names_and_taxonomy" } ] }, { "name": "Neuromedin-B-preferring bombesin receptor", "type": "synonym", "evidence": [ { "id": "E1BMN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN4/entry#names_and_taxonomy" } ] }, { "name": "neuromedin-B receptor", "type": "synonym", "evidence": [ { "id": "NP_001192639", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192639" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NMBR", "url": "https://www.uniprot.org/uniprotkb/E1BMN4", "locus": { "chromosome": "9", "start_pos": 79578213, "end_pos": 79586431, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000043954", "url": "https://www.ensembl.org/id/ENSBTAG00000043954" } ] } } ], "crossref": [ { "id": "E1BMN4", "url": "https://alphafold.ebi.ac.uk/entry/E1BMN4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000043954", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000043954", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15125", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15125", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539776", "url": "https://www.ncbi.nlm.nih.gov/gene/539776", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001556", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001556", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539776", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539776", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GWERDFL", "url": "https://omabrowser.org/oma/group/GWERDFL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMN4", "url": "https://www.orthodb.org/?gene=E1BMN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192639", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192639", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMN4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPESLSNLSQPAGGNRSGFVPGMSERDFLPAPDGTTAELVIRCVIPSLYLIIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDVLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDIQTSGAVLWTCVKAVGIWVVSVLLAIPEAIFSQVARVGSLDNGSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISVYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNKIDPSLGHMIVTLVARVLSFCNSCVNPFALYLLSESFRRHFNSQLCCGRKSYGERSTSYLLSSSAVRMTSLKSNAKNVVTNSVLLNGHSVKQEMAL", "length": 390, "header": "tr|E1BMN4-1|E1BMN4_BOVIN Isoform 1 of Neuromedin-B receptor OS=Bos taurus OX=9913 GN=NMBR PE=3 SV=1 CANONICAL=E1BMN4-1" }, "isoforms": [ { "isoform_ac": "E1BMN4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMN4/entry#E1BMN4-1", "sequence": { "sequence": "MPPESLSNLSQPAGGNRSGFVPGMSERDFLPAPDGTTAELVIRCVIPSLYLIIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDVLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDIQTSGAVLWTCVKAVGIWVVSVLLAIPEAIFSQVARVGSLDNGSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISVYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNKIDPSLGHMIVTLVARVLSFCNSCVNPFALYLLSESFRRHFNSQLCCGRKSYGERSTSYLLSSSAVRMTSLKSNAKNVVTNSVLLNGHSVKQEMAL", "length": 390, "header": "tr|E1BMN4-1|E1BMN4_BOVIN Isoform 1 of Neuromedin-B receptor OS=Bos taurus OX=9913 GN=NMBR PE=3 SV=1 CANONICAL=E1BMN4-1" }, "locus": { "chromosome": "9", "start_pos": 79586431, "end_pos": 79578446, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061022.3", "url": "https://www.ensembl.org/id/ENSBTAT00000061022.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053601.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053601.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539776", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539776", "resource": "KEGG Pathway" }, { "id": "R-BTA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-BTA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HAV5-1", "protein_name": "Neuromedin-B receptor", "gene_name": "Nmbr", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPPRFLSNLSLPMEANESELVPEVWEKDFLPHSDGTTAELVIRCVIPSLYLVIITVGLLGNIILVKIFLTNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWVFGKLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGVVLWTSVKAVGIWVVSVLLAVPEAVFSEVAQIGSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISIYYYHIAKTLIKSAHNLPGESNEHTKRQMETRKRLAKIVLVFVACFVFCWFPNHVLYLYRSFNYKEIDPSLGHMIVTLVARVLSFSNSCVNPFALYLLSESFRKHFNSQLCCRRKSYPERSTSYLVSSSAVRMTSLKSNTKNVVTSSVLLNGHSMKQEIAL", "length": 390 }, "evidence": [ { "id": "E1BMN4", "url": "https://omabrowser.org/oma/group/E1BMN4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O54799-1", "protein_name": "Neuromedin-B receptor", "gene_name": "Nmbr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPRSLSNLSFPTEANESELVPEVWEKDFLPDSDGTTAELVIRCVIPSLYLIIISVGLLGNIMLVKIFLTNSAMRNVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWVFGKLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGVLLWTSLKAVGIWVVSVLLAVPEAVFSEVARIGSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFVFCWFPNHVLYLYRSFNYKEIDPSLGHMIVTLVARVLSFSNSCVNPFALYLLSESFRKHFNSQLCCGRKSYPERSTSYLLSSSAVRMTSLKSNTKNVVTNSVLLNGHSTKQEIAL", "length": 390 }, "evidence": [ { "id": "E1BMN4", "url": "https://omabrowser.org/oma/group/E1BMN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28336-1", "protein_name": "Neuromedin-B receptor", "gene_name": "NMBR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL", "length": 390 }, "evidence": [ { "id": "E1BMN4", "url": "https://omabrowser.org/oma/group/E1BMN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of interferon-alpha production", "id": "GO:0032727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032727", "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "pmid": "" }, { "name": "negative regulation of interleukin-6 production", "id": "GO:0032715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715", "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "pmid": "" }, { "name": "positive regulation of osteoclast proliferation", "id": "GO:0090290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090290", "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "pmid": "" }, { "name": "positive regulation of respiratory gaseous exchange", "id": "GO:1903942", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903942", "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "pmid": "" }, { "name": "sneeze reflex", "id": "GO:0160023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160023", "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "neuropeptide receptor activity", "id": "GO:0008188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008188", "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "pmid": "" }, { "name": "bombesin receptor activity", "id": "GO:0004946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004946", "evidence": [ { "database": "UniProtKB", "id": "E1BMN4", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMN4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 390, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMN4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMN4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 324, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMN6-1", "uniprot_ac": "E1BMN6", "uniprot_id": "E1BMN6_BOVIN", "mass": { "chemical_mass": 57643.0, "monoisotopic_mass": 57643.0 }, "refseq": { "ac": "NP_001107241", "name": "carbohydrate sulfotransferase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107241" }, "gene_names": [ { "name": "CHST2", "type": "recommended", "evidence": [ { "id": "E1BMN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" } ] }, { "name": "CHST2", "type": "synonym", "evidence": [ { "id": "NP_001107241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107241" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "E1BMN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN6/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "E1BMN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN6/entry#names_and_taxonomy" } ] }, { "name": "carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2", "type": "synonym", "evidence": [ { "id": "NP_001107241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107241" } ] }, { "name": "carbohydrate sulfotransferase 2", "type": "synonym", "evidence": [ { "id": "NP_001107241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107241" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMN6", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CHST2", "url": "https://www.uniprot.org/uniprotkb/E1BMN6", "locus": { "chromosome": "1", "start_pos": 125869073, "end_pos": 125875559, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011584", "url": "https://www.ensembl.org/id/ENSBTAG00000011584" } ] } } ], "crossref": [ { "id": "E1BMN6", "url": "https://alphafold.ebi.ac.uk/entry/E1BMN6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011584", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011584", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "615978", "url": "https://www.ncbi.nlm.nih.gov/gene/615978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:615978", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYKWHKG", "url": "https://omabrowser.org/oma/group/DYKWHKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMN6", "url": "https://www.orthodb.org/?gene=E1BMN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10704", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10704", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10704:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10704:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022854", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001107241", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "67856", "url": "https://www.rhea-db.org/rhea/67856", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "67860", "url": "https://www.rhea-db.org/rhea/67860", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "67864", "url": "https://www.rhea-db.org/rhea/67864", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "67868", "url": "https://www.rhea-db.org/rhea/67868", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "82911", "url": "https://www.rhea-db.org/rhea/82911", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "82975", "url": "https://www.rhea-db.org/rhea/82975", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "84275", "url": "https://www.rhea-db.org/rhea/84275", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BMN6", "url": "https://www.uniprot.org/uniprotkb/E1BMN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMN6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSPPRALPAGAPLGLLPAAPAAGPRALLPPWPRRLGRRWPASPLGMKVFRRKALVLCAGYALLLVLTMLNLLDYKWHKEPLQQCSPDGSLGAGAGAASGGWGRPGPPPAVPPRAHTRLDPRTPYRPPVAAVQAAPAVAAGAARAAAPPGNGTRGGGDKRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSALYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAYRKEVVGLVDDRVCKKCPPQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLRDPALDLKVIHLVRDPRAVASSRIRSRHGLIRESLQVVRSRDPRAHRMPFLEAPGHKLGVKKESMGGPADYHALGAMEVICNSMAKTLQTALQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSGSGSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNSPEEVKDLSKTLLRKPRL", "length": 527, "header": "tr|E1BMN6-1|E1BMN6_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=CHST2 PE=3 SV=2 CANONICAL=E1BMN6-1" }, "isoforms": [ { "isoform_ac": "E1BMN6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMN6/entry#E1BMN6-1", "sequence": { "sequence": "MSRSPPRALPAGAPLGLLPAAPAAGPRALLPPWPRRLGRRWPASPLGMKVFRRKALVLCAGYALLLVLTMLNLLDYKWHKEPLQQCSPDGSLGAGAGAASGGWGRPGPPPAVPPRAHTRLDPRTPYRPPVAAVQAAPAVAAGAARAAAPPGNGTRGGGDKRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSALYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAYRKEVVGLVDDRVCKKCPPQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLRDPALDLKVIHLVRDPRAVASSRIRSRHGLIRESLQVVRSRDPRAHRMPFLEAPGHKLGVKKESMGGPADYHALGAMEVICNSMAKTLQTALQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSGSGSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNSPEEVKDLSKTLLRKPRL", "length": 527, "header": "tr|E1BMN6-1|E1BMN6_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=CHST2 PE=3 SV=2 CANONICAL=E1BMN6-1" }, "locus": { "chromosome": "1", "start_pos": 125874332, "end_pos": 125872752, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015389.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015389.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041637.3", "url": "https://www.ensembl.org/id/ENSBTAP00000041637.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:615978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615978", "resource": "KEGG Pathway" }, { "id": "R-BTA-2022854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022854", "resource": "Reactome", "description": "Keratan sulfate biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NVT2-1", "protein_name": "Sulfotransferase", "gene_name": "CHST2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKVCRRKALALCLGYALLLLLAALNLLEYKWRREPRRCGEPPAVPRQRPPPPPAGSSAPQGGRRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSSLYRCDLSVFQLYSTAGAGKNLTTLGIFGAATNKVICSSPLCPAYRKEVVGMVDDRVCKKCPPQRLSRFQEECHKYRTLVIKGVRVFDLAVLAPLMRDPTLDLKVIHLVRDPRAVASSRIKSRHGLIRESLQVVRSRDPRIHRMPFLETGHKLGGKKDGGGGSDYHALGAMEVICSSMAKTLQTALHPPDWLQGNYMAVRYEDLVMEPIKTLRQVYGFVNLAVSPEMEKFTLNMTSGPGYSSKPFVVSARNATQALSAWRTALSFQQIKQVEEYCQQPMALLGYERVGSPEEVKDLSRTLLRKPRL", "length": 427 }, "evidence": [ { "id": "E1BMN6", "url": "https://omabrowser.org/oma/group/E1BMN6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3L6A5-1", "protein_name": "Sulfotransferase", "gene_name": "CHST2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLNLLDYKWHKEPLQQCNPDGPLGAAAAGGAGGGWGRPGPPPAVPPHAHTRLDPRTPHRPPVAAVGAAPAAGAGAPGAAASSGNGTRSSTGGGGGDKRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSALYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAYRKEVVGLVDDRVCKKCPPQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLRDPTLDLKVIHLVRDPRAVASSRIRSRHGLIRESLQVVRSRDPRAHRMPFLEAAGHKLGAKKEGIGGPADYHALGAMEVICNSMAKTLQTALQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSGSGSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNSPEEVKDLSKTLLRKPRL", "length": 464 }, "evidence": [ { "id": "E1BMN6", "url": "https://omabrowser.org/oma/group/E1BMN6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7DYB2-1", "protein_name": "Sulfotransferase", "gene_name": "chst2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRSNQFLQLQLPALGEKNGVYDRNLKTYRNHSTKIITQPGIVMKVLRRKRIILFIAYFLLLVLTMLNLANYRWTKEPQQCNVQMRSTPYQGRSDMRFLYRPSLAKKRQLVYVLTTWRSGSSFFGELFNQHPEVFFLYEPMWHIWQKLYPGDAVSLQGAARDMLSSLYRCDLSVFQLYNSPGGKNFTSLGLFGATLNKVICSYPLCSAYRKDVVGMVDDKVCKKCPPQSLRLLEEECLKYNTIVIKGVRVLDVNVLAPLMEDPSLDLKVIHLVRDPRAVANSRIKSRHGLIRENLQVVRSRDPKLRRIHFVDPGHKISKKDGADYHSVGAMEVICDRTYRSLRTALNPPAWLKGKYLAVRYEDLVDNPVKTLRNVYQFANISANLDIESFALNMTNGTSSSSKPFIVSARNATQAASAWRTVLSIQQIKQVEEYCHHAMAILGYEHVRTAGEAKDLSKSLLTASKL", "length": 465 }, "evidence": [ { "id": "E1BMN6", "url": "https://omabrowser.org/oma/group/E1BMN6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R868-1", "protein_name": "Sulfotransferase", "gene_name": "Chst2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSSPRALPPGALPRPLPAAPAAVQRALLPPWPRRAGRRWPASPLGMKVFRRKALVLCAGYALLLVLTMLNLLDYKWHKEPLQQCNPDGPLGAAVGAAGAGWGRPGSPPAAPPRAHSRMDPRTPYRPPAAGVGAVPAAAAGSVGAAASLGNATRGTRGGGDKRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSALYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAYRKEVVGLVDDRVCKKCPPQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLKDPALDLKVIHLVRDPRAVASSRIRSRHGLIRESLQVVRSRDPRAHRMPFLEAAGHKLGAKKEGMGGPADYHALGAMEVICNSMAKTLQTALQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSGSGSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNSPEEVKDLSKSLLRKPRL", "length": 530 }, "evidence": [ { "id": "E1BMN6", "url": "https://omabrowser.org/oma/group/E1BMN6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80WV3-1", "protein_name": "Carbohydrate sulfotransferase 2", "gene_name": "Chst2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRSSPRALPPGALPRPLPAAPAAVQRALLPPWPRRAGRRWPASPLGMKVFRRKALVLCAGYALLLVLTMLNLLDYKWHKEPLQQCNPDGPLGAAVGAAGAGWGRPGSPPAAPPRAHSRMDPRTPYRPPAAGVGAVPAAAAGSAGAAASLGNATRGTRGGGDKRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSALYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAYRKEVVGLVDDRVCKKCPPQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLKDPALDLKVIHLVRDPRAVASSRIRSRHGLIRESLQVVRSRDPRAHRMPFLEAAGHKLGAKKEGMGGPADYHALGAMEVICNSMAKTLQTALQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSGSGSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNSPEEVKDLSKTLLRKPRL", "length": 530 }, "evidence": [ { "id": "E1BMN6", "url": "https://omabrowser.org/oma/group/E1BMN6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y4C5-1", "protein_name": "Carbohydrate sulfotransferase 2", "gene_name": "CHST2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSPQRALPPGALPRLLQAAPAAAPRALLPQWPRRPGRRWPASPLGMKVFRRKALVLCAGYALLLVLTMLNLLDYKWHKEPLQQCNPDGPLGAAAGAAGGSWGRPGPPPAGPPRAHARLDLRTPYRPPAAAVGAAPAAAAGMAGVAAPPGNGTRGTGGVGDKRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSALYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAYRKEVVGLVDDRVCKKCPPQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLRDPALDLKVIHLVRDPRAVASSRIRSRHGLIRESLQVVRSRDPRAHRMPFLEAAGHKLGAKKEGVGGPADYHALGAMEVICNSMAKTLQTALQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSGSGSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNSPEEVKDLSKTLLRKPRL", "length": 530 }, "evidence": [ { "id": "E1BMN6", "url": "https://omabrowser.org/oma/group/E1BMN6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "N-acetylglucosamine 6-O-sulfotransferase activity", "id": "GO:0001517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001517", "evidence": [ { "database": "UniProtKB", "id": "E1BMN6", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "N-acetylglucosamine metabolic process", "id": "GO:0006044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006044", "evidence": [ { "database": "UniProtKB", "id": "E1BMN6", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" } ], "pmid": "" }, { "name": "positive regulation of leukocyte tethering or rolling", "id": "GO:1903238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903238", "evidence": [ { "database": "UniProtKB", "id": "E1BMN6", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "E1BMN6", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "E1BMN6", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" } ], "pmid": "" }, { "name": "sulfur compound metabolic process", "id": "GO:0006790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006790", "evidence": [ { "database": "UniProtKB", "id": "E1BMN6", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BMN6", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "E1BMN6", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "67856", "name": "", "equation": "3-O-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + 3'-phosphoadenylyl sulfate = 3-O-{6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BMN6-1" ], "evidence": [ { "id": "67856", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67856" } ] }, { "id": "67860", "name": "", "equation": "a 3-O-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + 3'-phosphoadenylyl sulfate = a 3-O-{6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BMN6-1" ], "evidence": [ { "id": "67860", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67860" } ] }, { "id": "67864", "name": "", "equation": "a 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + 3'-phosphoadenylyl sulfate = 3-O-{beta-D-galactosyl-(1->3)-[6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BMN6-1" ], "evidence": [ { "id": "67864", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67864" } ] }, { "id": "67868", "name": "", "equation": "3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + 3'-phosphoadenylyl sulfate = 3-O-{beta-D-galactosyl-(1->3)-[6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BMN6-1" ], "evidence": [ { "id": "67868", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67868" } ] }, { "id": "82911", "name": "", "equation": "an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + 3'-phosphoadenylyl sulfate = a 6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BMN6-1" ], "evidence": [ { "id": "82911", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/82911" } ] }, { "id": "82975", "name": "", "equation": "an N(4)-{alpha-Neu5Ac-(2->6)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + 3'-phosphoadenylyl sulfate = an N(4)-{alpha-Neu5Ac-(2->6)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[6-O-sulfo-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BMN6-1" ], "evidence": [ { "id": "82975", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/82975" } ] }, { "id": "84275", "name": "", "equation": "N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + 3'-phosphoadenylyl sulfate = an N(4)-{6-O-sulfo-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L--asparaginyl-[protein] + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BMN6-1" ], "evidence": [ { "id": "84275", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/84275" } ] }, { "id": "R-BTA-2046222", "name": "CHST2,3,5,6 transfer sulfate to GlcNAc on keratan chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BMN6-1" ], "evidence": [ { "id": "R-BTA-2046222", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2046222" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BMN6", "gene_name": "CHST2", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BMN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMN6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 527, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMN6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMN6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN6" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 320, "end_pos": 501, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 472, "end_pos": 474 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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] }, { "id": "IPR037720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037726", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037726", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617299", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617299", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YYYLPYW", "url": "https://omabrowser.org/oma/group/YYYLPYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMQ1", "url": "https://www.orthodb.org/?gene=E1BMQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12546", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12546", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12546:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12546:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08150", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08150", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001137579", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137579", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BMQ1", "url": "https://www.uniprot.org/uniprotkb/E1BMQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMQ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLVHLKTVSELRGKGDRIAKVTFRGQSFYSRVLESCEDVADFDETFRWPVASSIDSNEMLEIQIFNYSKVFSNKLIGTFRMVLQKVVEENHVEVTDTLMDDNNAIIKTSLCVEVRYQATDGTVGSWDDGDFLGEESLHEEEKDSQETDGLLPGSRPSSRPSGEKSFRRAGRSVFSAMKLGKNRPHKEEPQRQDEPAVLEMEDLDRLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKPDIKMEPSAGRPMDYQVSVTVIEARQLVGLNMDPVVCVEVGDEKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAVLSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFTGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPEITSSTEVQVEQATPISESCTGKIEEFFLFGAFLEASMIDRKNGDKPITFEVTVGNYGNEVDGLSRPHRPRPRKEPGDEEEVDLIQNLSDEETDEGGGLASVSSTPPMRPQITDRNYFHLPYLEHKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLEELSSGCYRFLSLADKDQGHSSRTRLDRERLKSCMRELESMGQQAKTLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYTRVPSKDLLFSIVEEELGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLLSFPPISLVYTKKQAFQLRAHMYQARSLFAADSTGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDTMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPAGKADLPPINGPVDMDRGPIMPVPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPNWNTSGRLLQGRRGLYSGGPSSRLTGEVVVSMEPEVPIKKLETMVKLDATSDAVIKVDVAEEEKERKKKKKKGSSDEPEEEEPDESMLDWWSKYFASIDTMKEQIRQQEISGIDLEEKEEMDNTEGLKGPMKGKEKARAAKEEKKKRTQSLGPGQGSEAPEKRKPKIDELKVYPKELESEFDNFEDWLHTFNLLRGKTGDDEDGGTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDPTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEACFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSVHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGPPGRVKVSNRIFTGPSEIEDENGQRKPTEEHVALLALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPSPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLMLALFLYSLPGYMVKKLLGA", "length": 1998, "header": "tr|E1BMQ1-1|E1BMQ1_BOVIN Isoform 1 of Otoferlin OS=Bos taurus OX=9913 GN=OTOF PE=3 SV=1 CANONICAL=E1BMQ1-1" }, "isoforms": [ { "isoform_ac": "E1BMQ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMQ1/entry#E1BMQ1-1", "sequence": { "sequence": "MALLVHLKTVSELRGKGDRIAKVTFRGQSFYSRVLESCEDVADFDETFRWPVASSIDSNEMLEIQIFNYSKVFSNKLIGTFRMVLQKVVEENHVEVTDTLMDDNNAIIKTSLCVEVRYQATDGTVGSWDDGDFLGEESLHEEEKDSQETDGLLPGSRPSSRPSGEKSFRRAGRSVFSAMKLGKNRPHKEEPQRQDEPAVLEMEDLDRLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKPDIKMEPSAGRPMDYQVSVTVIEARQLVGLNMDPVVCVEVGDEKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAVLSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFTGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPEITSSTEVQVEQATPISESCTGKIEEFFLFGAFLEASMIDRKNGDKPITFEVTVGNYGNEVDGLSRPHRPRPRKEPGDEEEVDLIQNLSDEETDEGGGLASVSSTPPMRPQITDRNYFHLPYLEHKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLEELSSGCYRFLSLADKDQGHSSRTRLDRERLKSCMRELESMGQQAKTLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYTRVPSKDLLFSIVEEELGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLLSFPPISLVYTKKQAFQLRAHMYQARSLFAADSTGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDTMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPAGKADLPPINGPVDMDRGPIMPVPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPNWNTSGRLLQGRRGLYSGGPSSRLTGEVVVSMEPEVPIKKLETMVKLDATSDAVIKVDVAEEEKERKKKKKKGSSDEPEEEEPDESMLDWWSKYFASIDTMKEQIRQQEISGIDLEEKEEMDNTEGLKGPMKGKEKARAAKEEKKKRTQSLGPGQGSEAPEKRKPKIDELKVYPKELESEFDNFEDWLHTFNLLRGKTGDDEDGGTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDPTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEACFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSVHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGPPGRVKVSNRIFTGPSEIEDENGQRKPTEEHVALLALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPSPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLMLALFLYSLPGYMVKKLLGA", "length": 1998, "header": "tr|E1BMQ1-1|E1BMQ1_BOVIN Isoform 1 of Otoferlin OS=Bos taurus OX=9913 GN=OTOF PE=3 SV=1 CANONICAL=E1BMQ1-1" }, "locus": { "chromosome": "11", "start_pos": 73093732, "end_pos": 73006638, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015350.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015350.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015350.3", "url": "https://www.ensembl.org/id/ENSBTAP00000015350.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617299", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617299", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9ERC5-1", "protein_name": "Otoferlin", "gene_name": "Otof", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALIVHLKTVSELRGRADRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEVLEIQIFNYSKVFSNKLIGTFRMVLQKVVEENRVEVSDTLIDDNNAIIKTSLSMEVRYQAADGTVGPWDDGDFLGDESLQEEEKDSQETDGLLPGSRPSTRTPGEKSFRSKGKEKTKGGRDGEHKAGRSVFSAMKLGKTRSHKEEPQRQDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTSNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPELTSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDRKNGDKPVTFEVTIGNYGNEVDGTSRPQRPRPRKEPGDEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQITDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLEELSCGCHRFLSLSDKDQGHSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFSIVEEELGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQTFQLRAHMYQARSLFAADSTGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPSGKADLPPINGPVDMDRGPIMPVPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAANWNTTGEVVVSMEPEVPVKKLETLVKLDATSDAVVKVDVAEDEKERKKKKKKGPSEEAEEEEPDESMLDWWSKYFASIDTMKEQLRQHETSGIDLEEKEEMDSTEGLKGPVKNKEKSRAAKEEKKKKNQNPGPGQGSEAPEKKKAKIDELKVYPKELESEFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDPTYGMFQGIPSNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGPHGRVKVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLMLALFLYSLPGYMVKKLLGA", "length": 1993 }, "evidence": [ { "id": "E1BMQ1", "url": "https://omabrowser.org/oma/group/E1BMQ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ESF1-1", "protein_name": "Otoferlin", "gene_name": "Otof", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALIVHLKTVSELRGKGDRIAKVTFRGQSFYSRVLENCEGVADFDETFRWPVASSIDRNEVLEIQIFNYSKVFSNKLIGTFCMVLQKVVEENRVEVTDTLMDDSNAIIKTSLSMEVRYQATDGTVGPWDDGDFLGDESLQEEKDSQETDGLLPGSRPSTRISGEKSFRRAGRSVFSAMKLGKTRSHKEEPQRQDEPAVLEMEDLDHLAIQLGDGLDPDSVSLASVTALTSNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPELTSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDRKNGDKPITFEVTIGNYGNEVDGMSRPLRPRPRKEPGDEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQITDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLEELSCGCHRFLSLSDKDQGRSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFSIVEEELGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGSATAGDLLAAFELLQIGPSGKADLPPINGPVDMDRGPIMPVPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPNWNTTVRLLRGCHRLRNGGPSSRPTGEVVVSMEPEEPVKKLETMVKLDATSDAVVKVDVAEDEKERKKKKKKGPSEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQHETSGTDLEEKEEMESAEGLKGPMKSKEKSRAAKEEKKKKNQSPGPGQGSEAPEKKKAKIDELKVYPKELESEFDSFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDPTYGMFQGIPSNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGPHGRVRVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKFLLLFLLLLLFALFLYSLPGYLAKKILGA", "length": 1997 }, "evidence": [ { "id": "E1BMQ1", "url": "https://omabrowser.org/oma/group/E1BMQ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HC10-1", "protein_name": "Otoferlin", "gene_name": "OTOF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLIHLKTVSELRGRGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEMLEIQVFNYSKVFSNKLIGTFRMVLQKVVEESHVEVTDTLIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGDFLGDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFRRAGRSVFSAMKLGKNRSHKEEPQRPDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSNPELTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNEVDGLSRPQRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYPERRLRGVLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSIVEEETGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPAGKADLPPINGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELESEFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIEDENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKILGA", "length": 1997 }, "evidence": [ { "id": "E1BMQ1", "url": "https://omabrowser.org/oma/group/E1BMQ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "E1BMQ1", "url": "https://www.uniprot.org/uniprotkb/E1BMQ1" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BMQ1", "url": "https://www.uniprot.org/uniprotkb/E1BMQ1" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "E1BMQ1", "url": "https://www.uniprot.org/uniprotkb/E1BMQ1" } ], "pmid": "" }, { "name": 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"NP_001361397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001361397" } ] }, { "name": "short transient receptor potential channel 2 homolog", "type": "synonym", "evidence": [ { "id": "NP_001361397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001361397" } ] }, { "name": "transient receptor protein 2", "type": "synonym", "evidence": [ { "id": "NP_001361397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001361397" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMQ7", "url": "https://www.uniprot.org/uniprotkb/E1BMQ7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TRPC2", "url": "https://www.uniprot.org/uniprotkb/E1BMQ7", "locus": { "chromosome": "15", "start_pos": 51515258, "end_pos": 51532586, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011549", "url": "https://www.ensembl.org/id/ENSBTAG00000011549" } ] } } ], "crossref": [ { "id": "E1BMQ7", "url": "https://alphafold.ebi.ac.uk/entry/E1BMQ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011549", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011549", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "282101", "url": "https://www.ncbi.nlm.nih.gov/gene/282101", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:282101", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:282101", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR10117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10117:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10117:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001361397", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001361397", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BMQ7", "url": "https://www.uniprot.org/uniprotkb/E1BMQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMQ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRLTPQPNWTEIVNRKLKFPAPLLGAIQEGHTGLVQQLLEVGVEAPGGGPGGPPRNVEEAEDRSWREALNLAIRLGHEAITDVLLANVKFDFRQIHEALLVAVDTNQPAVVRHLLARLEREKGRKVDTRSSSLAFFDSSIDGSRFAPGVTPLTLACQKDLYEIAQLLMGQGHTIARPHPVSCACLECSNARRYDLLKFSLSRINTYRGIASRAHLSLASEDAMLAAFQLSRELRHLARKEPEFKPEYIALESLSQDYGFELLGMCRNQSEVTAVLNDLGEDSETEPEAEGLGQAFEEGIPNLARLRLAVNYNQKRFVAHPICQQVLSSIWCGNLAGWRGSTTIWKLFIAFLIFLTMPFLCLGYWLAPKSRLGRLLKIPVLKFLLHSASYLWFLIFLLGESLVMETQLSTFRGRSQSVWETSLHMVWVAGFLWFECKEVWIEGLRSYLLDWWNFLDMVILSLYLAAFTLRLLLAGLAHKHCRDAPDGAACHYFTSAERSEWRTEDPQFLAEVLFAVTSMLSFTRLASILPAHESLGTLQISMGRMIDDMIRFMFILMIILTAFLCGLNNIYVPYQETERLGNFNETFQFLFWTMFGMEEHSVVDMPQFLVPEFVGRALYGIFTIVMVIVLLNMLIAMITNSFQKIEDAADVEWKFARSKLYLSYFREGLTLPVPFNILPSPKAIFYLLRRVFRFICCCHLCCKTKKPDYPPIPTFANPGAGAGPGEGERGSYRLRVIKALVQRYIETAQREFEETRRKDLGNRLTELTKTVSRLQSEVAGVQRAVVEAGPRRPPGGASVLSRYITRVRNSFQNLGPPIPETPELTVPATVGTQESSETGLPDAGGAQAPASGESGPSSPAHVLVHREQESEGAGDLPQEADLGAKEGT", "length": 888, "header": "tr|E1BMQ7-1|E1BMQ7_BOVIN Isoform 1 of Transient receptor potential channel 2 OS=Bos taurus OX=9913 GN=TRPC2 PE=4 SV=4 CANONICAL=E1BMQ7-1" }, "isoforms": [ { "isoform_ac": "E1BMQ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMQ7/entry#E1BMQ7-1", "sequence": { "sequence": 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proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "E1BMR2", "url": "https://www.uniprot.org/uniprotkb/E1BMR2" } ], "pmid": "" }, { "name": "white fat cell differentiation", "id": "GO:0050872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050872", "evidence": [ { "database": "UniProtKB", "id": "E1BMR2", "url": "https://www.uniprot.org/uniprotkb/E1BMR2" } ], "pmid": "" }, { "name": "epidermal growth factor receptor signaling pathway", "id": "GO:0007173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007173", "evidence": [ { "database": "UniProtKB", "id": "E1BMR2", "url": "https://www.uniprot.org/uniprotkb/E1BMR2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BMR2", "url": "https://www.uniprot.org/uniprotkb/E1BMR2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E1BMR2", "url": "https://www.uniprot.org/uniprotkb/E1BMR2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BMR2", "url": "https://www.uniprot.org/uniprotkb/E1BMR2" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase regulatory subunit binding", "id": "GO:0036312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036312", "evidence": [ { "database": "UniProtKB", "id": "E1BMR2", "url": "https://www.uniprot.org/uniprotkb/E1BMR2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMR2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 435, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMR2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMR2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR2" }, { "id": "PF07894", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Scaffolding anchor of CK1", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 295, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 }, { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMR7-1", "uniprot_ac": "E1BMR7", "uniprot_id": "E1BMR7_BOVIN", "mass": { "chemical_mass": 58070.0, "monoisotopic_mass": 58070.0 }, "refseq": { "ac": "XP_002696085", "name": "N-acetylglutamate synthase, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696085" }, "gene_names": [ { "name": "NAGS", "type": "recommended", "evidence": [ { "id": "E1BMR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR7" } ] }, { "name": "NAGS", "type": "synonym", "evidence": [ { "id": "XP_002696085", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696085" } ] } ], "protein_names": [ { "name": "N-acetylglutamate synthase, mitochondrial", "type": "recommended", "evidence": [ { "id": "E1BMR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR7/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.1", "type": "synonym", "evidence": [ { "id": "E1BMR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR7/entry#names_and_taxonomy" } ] }, { "name": "Amino-acid acetyltransferase", "type": "synonym", "evidence": [ { "id": "E1BMR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR7/entry#names_and_taxonomy" } ] }, { "name": "N-acetylglutamate synthase, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_002696085", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696085" } ] } ], "function": [ { "annotation": "Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPS1) activity.", "evidence": [ { "database": "UniProtKB", "id": "E1BMR7", "url": "https://www.uniprot.org/uniprotkb/E1BMR7#function" }, { "database": "UniProtKB", "id": "ARBA00058188", "url": "https://www.uniprot.org/uniprotkb/ARBA00058188#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMR7", "url": "https://www.uniprot.org/uniprotkb/E1BMR7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NAGS", "url": "https://www.uniprot.org/uniprotkb/E1BMR7", "locus": { "chromosome": "19", "start_pos": 43867004, "end_pos": 43861433, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016249", "url": "https://www.ensembl.org/id/ENSBTAG00000016249" } ] } } ], "crossref": [ { "id": "E1BMR7", "url": "https://alphafold.ebi.ac.uk/entry/E1BMR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016249", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016249", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04264", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04264", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538004", "url": "https://www.ncbi.nlm.nih.gov/gene/538004", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538004", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538004", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQTCYHS", "url": "https://omabrowser.org/oma/group/FQTCYHS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMR7", "url": "https://www.orthodb.org/?gene=E1BMR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23342:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23342:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04768", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04768", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-70635", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70635", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002696085", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696085", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24292", "url": "https://www.rhea-db.org/rhea/24292", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BMR7", "url": "https://www.uniprot.org/uniprotkb/E1BMR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATVRMAWALWAAPAGRRLRGPRGTGSARRLSCGARRQATRGTSPGRRLSTAWGPAQLAQEEAEGGKDDVHPSAAEEPLWTPPPAPPVPPDSPGPPAGRSLVQRDIQTFLNQCGASPGEARHWLTQFQACHHSADRPFAVIEVDEEVVKCPKAVSSLAFALAFLQRMDMKPLVVLGLPAPTAPSGCLSFWEAKAQLAQRCKVLVDALRHNAAAAVPFFGGGSVLSAAEPAPHASYGGIVSVETDLLQWCLESGSIPILCPIGETAARRSVLLDSLEVTASLAKALRPTKIIFLNTTGGLHDGSHKVLSNVNLPADLDLVTNADWVSTKERQRIRLIVDVLSRLPHHSSAVITAASMLLTELFSNRGSGTLFKTCERTLRVRCLDSLDQGRLVNLVNASFGKKLRDDYLASLRPRLHSVYFSEGYNAAAILTTEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLKTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFCKPASDPGS", "length": 534, "header": "tr|E1BMR7-1|E1BMR7_BOVIN Isoform 1 of N-acetylglutamate synthase, mitochondrial OS=Bos taurus OX=9913 GN=NAGS PE=3 SV=2 CANONICAL=E1BMR7-1" }, "isoforms": [ { "isoform_ac": "E1BMR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMR7/entry#E1BMR7-1", "sequence": { "sequence": "MATVRMAWALWAAPAGRRLRGPRGTGSARRLSCGARRQATRGTSPGRRLSTAWGPAQLAQEEAEGGKDDVHPSAAEEPLWTPPPAPPVPPDSPGPPAGRSLVQRDIQTFLNQCGASPGEARHWLTQFQACHHSADRPFAVIEVDEEVVKCPKAVSSLAFALAFLQRMDMKPLVVLGLPAPTAPSGCLSFWEAKAQLAQRCKVLVDALRHNAAAAVPFFGGGSVLSAAEPAPHASYGGIVSVETDLLQWCLESGSIPILCPIGETAARRSVLLDSLEVTASLAKALRPTKIIFLNTTGGLHDGSHKVLSNVNLPADLDLVTNADWVSTKERQRIRLIVDVLSRLPHHSSAVITAASMLLTELFSNRGSGTLFKTCERTLRVRCLDSLDQGRLVNLVNASFGKKLRDDYLASLRPRLHSVYFSEGYNAAAILTTEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLKTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFCKPASDPGS", "length": 534, "header": "tr|E1BMR7-1|E1BMR7_BOVIN Isoform 1 of N-acetylglutamate synthase, mitochondrial OS=Bos taurus OX=9913 GN=NAGS PE=3 SV=2 CANONICAL=E1BMR7-1" }, "locus": { "chromosome": "19", "start_pos": 43866822, "end_pos": 43861632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021616.7", "url": "https://www.ensembl.org/id/ENSBTAT00000021616.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021616.5", "url": "https://www.ensembl.org/id/ENSBTAP00000021616.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:538004", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538004", "resource": "KEGG Pathway" }, { "id": "R-BTA-70635", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70635", "resource": "Reactome", "description": "Urea cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A904-1", "protein_name": "N-acetylglutamate synthase, mitochondrial", "gene_name": "Nags", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTCHTPNAPRSHSGPPIPPRPESDPAQLNGKLRTPSVVRSRPTVTCGWGRPVGLVVVMATAWVATALRSAAAARRLRSPGGPGGSRRLSGSARRRGARSASPGRRLSTARAHVEDNEGTKGRVQSPAVEEPPWTPLPTPLESPAPPAGKSLVQRDIQAFLNQCGASPGEARHWLTQFQTCYHSVDKPFAVVEVDEEVFGCPQAVSRLAFALAFLQRMDMKPLVVLGLPAPTAPSGCLSFWEAKAQLAQSCKVLVNELRHNAATAVPFFGGGSVLSAAEPAPHASYGGIVAVETDLLQWCLESNSIPILCPIGETAARRSVLLDSLEVTASLAKALQPTKIIFLNNSGGLRDTSQKILSNVNLPADLDLVTNAEWLSTKERQQIRLIVDVLSRLPHYSSAVITAASTLLTELFSNKGCGTLFKNAERMLRVRSLDSLDQGRLVNLVNASFGKKLREDYLESLRPRLHSIYVSEGYNAAAILTVEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFCKPASDPGS", "length": 584 }, "evidence": [ { "id": "E1BMR7", "url": "https://omabrowser.org/oma/group/E1BMR7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S1J0-1", "protein_name": "N-acetylglutamate synthase, mitochondrial", "gene_name": "NAGS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSLAFALAFLQRMDMKPLVVLGLPAPTAPSGCLSFWEAKAQLAQRCKVLVNTLRHNAATAVPFFGGGSVLGAAEPAPHASYSGIVSVETDLLQWCLESGSIPILCPIGETAARRSVLLDSLEVTAALAKALQPTKIIFLNTTGGICDSSHKVLSNVNLPADLDLVTNAEWVSTKERQQMRLIVDVLSRLPHHSSAVITAASTLLTELFSNKGSGTLFKNAERMLRVRSLDSLDQDRLVNLVNASFGKKLRDDYLASLRPRLHSVYVSEGYNAAAILTTEPVLGGTPYLDKFVVSSSRQGQGSGQMLWERLRRDLQTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFCKPASDPGS", "length": 381 }, "evidence": [ { "id": "E1BMR7", "url": "https://omabrowser.org/oma/group/E1BMR7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HLI7-1", "protein_name": "N-acetylglutamate synthase, mitochondrial", "gene_name": "Nags", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATAWVATALRSAAAARRLHNPGGPGGSRRLSGSARRRGAKSASPGRRLSTARPRAEDAEGAKGRVQSPAVEEPSWTPPPTPLESPAPPAGRSLVQRDIQAFLNQCGASPGEARHWLTQFQTCYHSVDKPFAVMEVDEAVFQCPQAVSSLAFALAFLQRMDMKPLVVLGLPAPTAPSGCLSFWEAKAQLAQSCKVLVDELRHNAATAVPFFGGGSVLSAAEPAPHASYGGIVSVETDLLQWCLESNSIPILCPIGETAVRRSVLLDSLEVTASLAKALQPTKIIFLNDSGGLRDTRQKILSNVNLPADLDLVTNAEWLSIKERQQIRLIVDVLSRLPHYSSAVITSASTLLTELFSNKGCGTLFKNAERMLRVSSLDSLDQGRLVNLVNTSFGRKLRDDYLESLRPRLHSIYVSEGYNAAAILTVEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFCKPASDPGS", "length": 527 }, "evidence": [ { "id": "E1BMR7", "url": "https://omabrowser.org/oma/group/E1BMR7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8N159-1", "protein_name": "N-acetylglutamate synthase, mitochondrial", "gene_name": "NAGS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATALMAVVLRAAAVAPRLRGRGGTGGARRLSCGARRRAARGTSPGRRLSTAWSQPQPPPEEYAGADDVSQSPVAEEPSWVPSPRPPVPHESPEPPSGRSLVQRDIQAFLNQCGASPGEARHWLTQFQTCHHSADKPFAVIEVDEEVLKCQQGVSSLAFALAFLQRMDMKPLVVLGLPAPTAPSGCLSFWEAKAQLAKSCKVLVDALRHNAAAAVPFFGGGSVLRAAEPAPHASYGGIVSVETDLLQWCLESGSIPILCPIGETAARRSVLLDSLEVTASLAKALRPTKIIFLNNTGGLRDSSHKVLSNVNLPADLDLVCNAEWVSTKERQQMRLIVDVLSRLPHHSSAVITAASTLLTELFSNKGSGTLFKNAERMLRVRSLDKLDQGRLVDLVNASFGKKLRDDYLASLRPRLHSIYVSEGYNAAAILTMEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFHKPASDPGS", "length": 534 }, "evidence": [ { "id": "E1BMR7", "url": "https://omabrowser.org/oma/group/E1BMR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R4H7-1", "protein_name": "N-acetylglutamate synthase, mitochondrial", "gene_name": "Nags", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATAWVATALRSAAAARRLRSPGGPGGSRRLSGSARRRGAKSASPGRRLSTARAHAEDAEGAKGRVQSPAVEEPSWTPLPTPLESPAPPAGRSLVQRDIQAFLNQCGASPGEARHWLTQFQTCYHSVDKPFAVMEVDEEVIRCPQAVSRLAFALAFLQRMDMKPLVVLGLPTPTAPSGCLSFWEAKAQLAQSCKVLVDELRHNAATAVPFFGGGSVLSAAEPAPHASYGGIVAVETDLLQWCLESNSIPILCPIGETAARRSVLLDSLEVTASLAKALQPTKIIFLNNSGGLRNNSQKILSNVNLPADLDLVTNAEWLSIKERQQIRLIVDVLSRLPHYSSAVITAASTLLTELFSNKGCGTLFKNAERMLRVRNLDSLDQGRLVNLVNASFGKKLREDYLESLRPRLHSIYVSEGYNAAAILTVEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFCKPASDPGS", "length": 527 }, "evidence": [ { "id": "E1BMR7", "url": "https://omabrowser.org/oma/group/E1BMR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "L-glutamate N-acetyltransferase activity", "id": "GO:0004042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004042", "evidence": [ { "database": "UniProtKB", "id": "E1BMR7", "url": "https://www.uniprot.org/uniprotkb/E1BMR7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "E1BMR7", "url": "https://www.uniprot.org/uniprotkb/E1BMR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "glutamate metabolic process", "id": "GO:0006536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006536", "evidence": [ { "database": "UniProtKB", "id": "E1BMR7", "url": "https://www.uniprot.org/uniprotkb/E1BMR7" } ], "pmid": "" }, { "name": "urea cycle", "id": "GO:0000050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000050", "evidence": [ { "database": "UniProtKB", "id": "E1BMR7", "url": "https://www.uniprot.org/uniprotkb/E1BMR7" } ], "pmid": "" }, { "name": "L-arginine biosynthetic process", "id": "GO:0006526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006526", "evidence": [ { "database": "UniProtKB", "id": "E1BMR7", "url": "https://www.uniprot.org/uniprotkb/E1BMR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24292", "name": "", "equation": "L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BMR7-1" ], "evidence": [ { "id": "24292", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24292" } ] }, { "id": "R-BTA-70542", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-30471" ], "enzyme_list": [ "E1BMR7-1" ], "evidence": [ { "id": "R-BTA-70542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70542" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-30471", "participant_name": "NAcGlu [mitochondrial matrix]", "crossref": [ { "id": "17533", "database": "ChEBI", "url": "" }, { "id": "C00624", "database": "COMPOUND", "url": "" }, { "id": "HMDB0001138", "database": "HMDB Metabolite", "url": "" }, { "id": "ZINC000001532704", "database": "ZINC", "url": "" }, { "id": "8144112", "database": "PubChem Substance", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BMR7", "gene_name": "NAGS", "activity": [ { "ec_number": "2.3.1.1", "activity": "L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+).", "evidence": [ { "id": "E1BMR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR7" } ] }, { "ec_number": "2.3.1.1", "activity": "", "evidence": [ { "id": "E1BMR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR7" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMR7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 534, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMR7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMR7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR7" }, { "id": "PS51731", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51731" }, { "id": "PS51186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 375, "end_pos": 526, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.1", "ec_name": "L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+).", "evidence": [ { "id": "2.3.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.1" }, { "id": "2.3.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.1" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 294, "end_pos": 296 }, { "start_pos": 396, "end_pos": 398 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMU6-1", "uniprot_ac": "E1BMU6", "uniprot_id": "E1BMU6_BOVIN", "mass": { "chemical_mass": 89606.0, "monoisotopic_mass": 89606.0 }, "refseq": { "ac": "XP_005220005", "name": "A-kinase anchor protein 1, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220005" }, "gene_names": [ { "name": "AKAP1", "type": "recommended", "evidence": [ { "id": "E1BMU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMU6" } ] }, { "name": "AKAP1", "type": "synonym", "evidence": [ { "id": "XP_005220005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220005" } ] } ], "protein_names": [ { "name": "A-kinase anchor protein 1, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_005220005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220005" } ] }, { "name": "A-kinase anchoring protein 1", "type": "synonym", "evidence": [ { "id": "E1BMU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMU6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMU6", "url": "https://www.uniprot.org/uniprotkb/E1BMU6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AKAP1", "url": "https://www.uniprot.org/uniprotkb/E1BMU6", "locus": { "chromosome": "19", "start_pos": 7964797, "end_pos": 7931794, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025320", "url": "https://www.ensembl.org/id/ENSBTAG00000025320" } ] } } ], "crossref": [ { "id": "E1BMU6", "url": "https://alphafold.ebi.ac.uk/entry/E1BMU6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000025320", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000025320", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22395", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22395", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532072", "url": "https://www.ncbi.nlm.nih.gov/gene/532072", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018459", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018459", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047368", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047368", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532072", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532072", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CLTNIYT", "url": "https://omabrowser.org/oma/group/CLTNIYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMU6", "url": "https://www.orthodb.org/?gene=E1BMU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22948:SF75", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948:SF75", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005220005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220005", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BMU6", "url": "https://www.uniprot.org/uniprotkb/E1BMU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMU6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTIQFRSLFPLALPGVLALLGWWWFFSRKKEPLDSHDRAAEAGAVALRAGPEAQEVLPVEDSRPGAASPPPERELCGGGRPSPEPAALLRAHPACRRSESSGSLPNPADTRLRPGARKEVELTLAGDEAKAVPLECPLPAPKGLPFPHEAVEVCKREAVLGRPGGRGRQGQPAAPAEKPAPEEKARETGGAEGTGDAVLGENVLEEGPAAWEPAPELELQSSRAAGAGEKDPGRLLEEAVVEAAPEEETLAPRGLAGRAWDGAFPQEQGGEETWDRSEKIEQAAFQIISKVILEATEEVLATTMGRIAGRVYQASATQPQGLKEESCAPASQKTPLGLEASEPTLTAVEAAPGLRDTALPSTEPPAGDLPAPKTYVSCLSSPLSSPTKDRKPKNSAHHISLAPCPLPAAPLRELLDEAGGTGEETTHVPCVSDGGQAVPCGAASGQCSDSASTSGLEDCCLETSPSPRGEAATPPLPESTVPVSNGVLKGELSDLGTEDGWTVDAEADHSGGSDGNSMDSVDSCCGFRKPDDFQNAQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQVCHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGVTVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGVDGAWWRAQVVAAYEDTNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVMPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSCYSSL", "length": 843, "header": "tr|E1BMU6-1|E1BMU6_BOVIN Isoform 1 of A-kinase anchoring protein 1 OS=Bos taurus OX=9913 GN=AKAP1 PE=4 SV=1 CANONICAL=E1BMU6-1" }, "isoforms": [ { "isoform_ac": "E1BMU6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMU6/entry#E1BMU6-1", "sequence": { "sequence": "MTIQFRSLFPLALPGVLALLGWWWFFSRKKEPLDSHDRAAEAGAVALRAGPEAQEVLPVEDSRPGAASPPPERELCGGGRPSPEPAALLRAHPACRRSESSGSLPNPADTRLRPGARKEVELTLAGDEAKAVPLECPLPAPKGLPFPHEAVEVCKREAVLGRPGGRGRQGQPAAPAEKPAPEEKARETGGAEGTGDAVLGENVLEEGPAAWEPAPELELQSSRAAGAGEKDPGRLLEEAVVEAAPEEETLAPRGLAGRAWDGAFPQEQGGEETWDRSEKIEQAAFQIISKVILEATEEVLATTMGRIAGRVYQASATQPQGLKEESCAPASQKTPLGLEASEPTLTAVEAAPGLRDTALPSTEPPAGDLPAPKTYVSCLSSPLSSPTKDRKPKNSAHHISLAPCPLPAAPLRELLDEAGGTGEETTHVPCVSDGGQAVPCGAASGQCSDSASTSGLEDCCLETSPSPRGEAATPPLPESTVPVSNGVLKGELSDLGTEDGWTVDAEADHSGGSDGNSMDSVDSCCGFRKPDDFQNAQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQVCHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGVTVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGVDGAWWRAQVVAAYEDTNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVMPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSCYSSL", "length": 843, "header": "tr|E1BMU6-1|E1BMU6_BOVIN Isoform 1 of A-kinase anchoring protein 1 OS=Bos taurus OX=9913 GN=AKAP1 PE=4 SV=1 CANONICAL=E1BMU6-1" }, "locus": { "chromosome": "19", "start_pos": 7963793, "end_pos": 7952412, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049153.6", "url": "https://www.ensembl.org/id/ENSBTAT00000049153.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046086.3", "url": "https://www.ensembl.org/id/ENSBTAP00000046086.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532072", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532072", "resource": "KEGG Pathway" }, { "id": "R-BTA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AP17-1", "protein_name": "A-kinase anchoring protein 1", "gene_name": "AKAP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALRFRTFFPYAIPGVLALLGCWWIYSHRKKHPSNRNRQAIAIAEGKQKELPENDSPPKTEACVPQRLPLSPEEERPENETSASLLPAGPMTPSPTRRTRERLDFSRDLSAPAIRTTQPSTVEDDSEKLEIKGSQDESSVPACVSLPLISKSTKCRSGAAVSPEEDSGSSTNQAKCPSASVVPTQRSLGITEEISNAEQSDESSLKPPKESQMPEIALSDTGCMTALHLGLEKEADAPQALLTNEVVLSHQDSAVRVLSGSLESACLEQSREEKIPESNDSTVPVCQGEDTHAKGNELERERIRGVSLDKEEVEKIEQVAIQIISKVILAATEEVLAGSVSDVSSRICQAAASRVERPQERASTASSDQLLAAEAGGGDKNTALKSDAAVPTSLPTEERDQCVTYSSCSALGHLSSPVQGDTQDHQEKNCVHSESQGVDRTLVASHGGSLGKSHLVMEDSGCSTCASEGGTSVEDPLQNTLLSVASGQHSDLLSTSATQDTSAEQSSEPSEKPPTLKLPEDSKVPYSNGMLKEDGSDSRHEGNWAAEMDGDHSGGSDVNSMDSVDSGCALGKTETHQNSKPGGESSKSDLTIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYSHDFQICHIEGSQHHVEKALSLIGKKFKELSLTNIYAPPPPSLTLHSLPMTSWLMLPDGVTVEVVVANQVNAGHMFLQQHTHPTFHVLRSLDQQMYVCYSQPGIPTLPTPVEVGIICAAPGLEGAWWRAQVVGYFKDSGEVEIRYVDYGGYERVKIDTLRQIRSDFVTLPFQGAEVLLDNVVPLPDEDHFSSEADAAVSEMTRGAALLAQVTNYDNATGLPLIQLWSMMGDEVVSINRTLVERGFAQWVDNY", "length": 883 }, "evidence": [ { "id": "E1BMU6", "url": "https://omabrowser.org/oma/group/E1BMU6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O08715-1", "protein_name": "A-kinase anchor protein 1, mitochondrial", "gene_name": "Akap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIQLRSLFPLALPGMLALLGWWWFFSRKKDRLSSSDKQVETLKVGPAIKDRRLSEEACPGVLSVAPTVTQPPGREEQRCVDKPSTEPLALPRTRQVRRRSESSGNLPSVADTRSQPGPCRDEIAKVELSLMGDKAKSIPLGCPLLPKDASFPYEAVERCKQESALGKTPGRGWPSPYAASGEKARETGGTEGTGDAVLGENVSEEGLLSQECVSEVEKSEFPILAPGGGEGEEVSHGPPQVAELLKKEEYIVGKLPSSFVEPVHSEPVKDEDALEPQVKGSSNTSDRDLAGELDKDETVPENDQIKQAAFQLISQVILEATEEFRATTVGKTVAQVHPTSATQPKGKEESCVPASQETSLGQDTSDPASTRTGATASPSAEALPPKTYVSCLSSPLSGPTKDQKPKNSAHHISLAPCPPPVTPQRQSLEGASNPRGDDNFVACMANNSQSVLSVSSLGQCSDPVSTSGLEDSCTETISSSGDKAMTPPLPVSTQPFSNGVLKEELSDLGTEDGWTMDTEADHSGGSDGNSMDSVDSCCGLTKPDSPQSVQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSATGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSYYASL", "length": 857 }, "evidence": [ { "id": "E1BMU6", "url": "https://omabrowser.org/oma/group/E1BMU6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O88884-1", "protein_name": "A-kinase anchor protein 1, mitochondrial", "gene_name": "Akap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIQFRSLFPLALPGMLALLGWWWFFSRKKDRLSSNGKQVGTLKVGPAIEDRLPTEEACPGVLSVTPSVTQPPGKEEQRSMDRPLSDPPALPRTRQVRRRSESSGNLPSIVDTRLQAGQCSDENSKVVLSLMGDEAKSIPLGRPLFPKDLSFPYEAVEGCKQESALGRTPGRGWLSQCAASGENARETGGAEGTGDAVLGESVLEEGLLPQECVSEVEKSEFPILAPGGGGGEKVRSGPPQVDELLKKEEYIVGKLPSSFVGPVHSELVKDEGALVPQVKGSQDRSLARELDKDKTLPEKDQIEQTAFQIISQVILEATEEIRATTVGKTVAQVHPTPGTQPQGQEESCVPASQETSLGQEIPDPASTRTGATASPSAGAPPPKTYVSCLSSPLSGPTKDQKPKNSAHHISLAPCPPPVTPQRQSLDGASNPRGDDTFVTCTSNNSQSVLSVTSLGLCSDPVSTSRLEDSCTETISSSGDKAVTPPLPDSTEPFSNGVLKEELSDLGTEDGWTMDTEADHSGGSDGNSMDSVDSCCGLTKPDSPQTVQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSATGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSCYASL", "length": 854 }, "evidence": [ { "id": "E1BMU6", "url": "https://omabrowser.org/oma/group/E1BMU6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q92667-1", "protein_name": "A-kinase anchor protein 1, mitochondrial", "gene_name": "AKAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPAEPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQPGYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSRFIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEATEQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDSKPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPESTVPFSNGVLKGELSDLGAEDGWTMDAEADHSGGSDRNSMDSVDSCCSLKKTESFQNAQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQSVQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSYYTSL", "length": 903 }, "evidence": [ { "id": "E1BMU6", "url": "https://omabrowser.org/oma/group/E1BMU6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BMU6", "url": "https://www.uniprot.org/uniprotkb/E1BMU6" } ], "pmid": "" }, { "name": "protein kinase A regulatory subunit binding", "id": "GO:0034237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034237", "evidence": [ { "database": "UniProtKB", "id": "E1BMU6", "url": "https://www.uniprot.org/uniprotkb/E1BMU6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BMU6", "url": "https://www.uniprot.org/uniprotkb/E1BMU6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BMU6", "url": "https://www.uniprot.org/uniprotkb/E1BMU6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1BMU6", "url": "https://www.uniprot.org/uniprotkb/E1BMU6" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "E1BMU6", "url": "https://www.uniprot.org/uniprotkb/E1BMU6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" }, { "start_pos": 824, "end_pos": 826, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMU6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 843, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMU6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMU6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMU6" }, { "id": "PS50304", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tudor", "eco_id": "ECO_0000259", "start_pos": 698, "end_pos": 757, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 619, "end_pos": 621 }, { "start_pos": 824, "end_pos": 826 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMV6-1", "uniprot_ac": "E1BMV6", "uniprot_id": "E1BMV6_BOVIN", "mass": { "chemical_mass": 13710.0, "monoisotopic_mass": 13710.0 }, "refseq": { "ac": "XP_002694280", "name": "V-type proton ATPase subunit G 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694280" }, "gene_names": [ { "name": "ATP6V1G3", "type": "recommended", "evidence": [ { "id": "E1BMV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMV6" } ] }, { "name": "ATP6V1G3", "type": "synonym", "evidence": [ { "id": "XP_002694280", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694280" } ] } ], "protein_names": [ { "name": "V-type proton ATPase subunit G", "type": "recommended", "evidence": [ { "id": "E1BMV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMV6/entry#names_and_taxonomy" } ] }, { "name": "V-type proton ATPase subunit G 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_002694280", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694280" } ] } ], "function": [ { "annotation": "Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.", "evidence": [ { "database": "UniProtKB", "id": "E1BMV6", "url": "https://www.uniprot.org/uniprotkb/E1BMV6#function" }, { "database": "UniProtKB", "id": "RU364019", "url": "https://www.uniprot.org/uniprotkb/RU364019#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMV6", "url": "https://www.uniprot.org/uniprotkb/E1BMV6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ATP6V1G3", "url": "https://www.uniprot.org/uniprotkb/E1BMV6", "locus": { "chromosome": "16", "start_pos": 77406107, "end_pos": 77427050, "strand": "+", "evidence": [ 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Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513140", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513140", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AVHCTSH", "url": "https://omabrowser.org/oma/group/AVHCTSH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMV7", "url": "https://www.orthodb.org/?gene=E1BMV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192679", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192679", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BMV7", "url": "https://www.uniprot.org/uniprotkb/E1BMV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMV7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPACQILHWALALGLGLAFEVTHAFRSQDEFLSSLDSYEIAFPTRVDHNGALLAFSPPAPRRQRRGTGPQAESRLFYKVAAPSTHFLLNLTHSPRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQASSSHVAISTCGGLHGLIVADEEEYLIEPLQGGPKGHRGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNRSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTEDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPALLGTGYEEVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQTQSLEALGPINASLIVMVLTQTELPALRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHHCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACLQPRPPVLEACHGPACPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCQPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGFGQQQRPVRCSSHTGQPSSECAEALRPPATQQCEAKCDSAPPGDGLEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR", "length": 1103, "header": "tr|E1BMV7-1|E1BMV7_BOVIN Isoform 1 of A disintegrin and metalloproteinase with thrombospondin motifs 10 OS=Bos taurus OX=9913 GN=ADAMTS10 PE=4 SV=1 CANONICAL=E1BMV7-1" }, "isoforms": [ { "isoform_ac": "E1BMV7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMV7/entry#E1BMV7-1", "sequence": { "sequence": "MAPACQILHWALALGLGLAFEVTHAFRSQDEFLSSLDSYEIAFPTRVDHNGALLAFSPPAPRRQRRGTGPQAESRLFYKVAAPSTHFLLNLTHSPRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQASSSHVAISTCGGLHGLIVADEEEYLIEPLQGGPKGHRGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNRSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTEDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPALLGTGYEEVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQTQSLEALGPINASLIVMVLTQTELPALRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHHCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACLQPRPPVLEACHGPACPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCQPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGFGQQQRPVRCSSHTGQPSSECAEALRPPATQQCEAKCDSAPPGDGLEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR", "length": 1103, "header": "tr|E1BMV7-1|E1BMV7_BOVIN Isoform 1 of A disintegrin and metalloproteinase with thrombospondin motifs 10 OS=Bos taurus OX=9913 GN=ADAMTS10 PE=4 SV=1 CANONICAL=E1BMV7-1" }, "locus": { "chromosome": "7", "start_pos": 17177735, "end_pos": 17160404, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018887.6", "url": "https://www.ensembl.org/id/ENSBTAT00000018887.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018887.4", "url": "https://www.ensembl.org/id/ENSBTAP00000018887.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:513140", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513140", "resource": "KEGG Pathway" }, { "id": "R-BTA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K229-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 10", "gene_name": "Adamts10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASACQILRWALALGLGLTFKVTHAFRSQDELLSSLESYEIAFPTRVDHNGAMLAFSPPALRRQRRGVGAAAESRLFYKVAAPSTHFLLNLTRSPRLLAGHVSVEYWTREGLAWQRAARAHCLYAGHLQGQAGSSHVAISTCGGLHGLIVADDEEYLIEPLQGGPKGRRGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPQGNETERGQLGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVSHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNGCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRSCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTNDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLADGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPALPGTGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTSQPHRLPLAGTTFHLRQGPDQAQSLEALGPINASLIIMVLAQAELPALRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQVVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACQGPMCPPEWAALDWSECTPSCGPGLRHRVVLCKSADQRSTLPPGHCPPAAKPPSTMRCNLRRCPPARWVASEWGECSTQCGLGQQQRTVRCTSHTGQPSRECTEALRPSTMQQCEAKCDSVVPPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR", "length": 1104 }, "evidence": [ { "id": "E1BMV7", "url": "https://omabrowser.org/oma/group/E1BMV7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A1D5NZ82-1", "protein_name": "ADAM metallopeptidase with thrombospondin type 1 motif, 10", "gene_name": "ADAMTS10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAIAWRLLIWTVTFTTTVCSFRGYMFQSQEEFLSSLDHYEIAFPIQVDQNGDFLTFDMRSQLKQRPRRSLGSLPYEPSEQQVFYKVSAHRTQFLLNLTLHSNLLAEHFTVEYWKRDGVDWQHDFHEDCHYAGHLQDQYLNSKVAISNCNGLHGVIVADEEEYFIEPLSPGANVSAGNEGKGSPHVVYKRSSLQYPHMDAACGVLDEKPWKGRHWWLRTLKPSPLKPSGNHSQRGQLPLKRSVSTERYVETLVVADKMMVGYHGRRDIEQYILAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEINHHAGKSLDSFCKWQKSIVNRNGNGNAIPENGIANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGSRGQETAKLMAAHITMKTNPFVWSTCSRDYITSFLDSGMGLCLNNAPPKQDFIYPTVAPGQAYDADEQCRFQYGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTICQTNTIEKGWCYKRECVPFGTRPEGVDGAWGSWSSWGECSRTCGGGVSSSVRHCDSPRPTIGGKYCLGERKRYRSCNTDDCPPGSQDFRELQCAEFDNVPFRGKYYTWKTYRGGGVKACSLNCLAEGFNFYTERAAAVVDGTPCRQDSNDICVNGECKHVGCDRVLGSDAKEDKCRVCGGDGSSCETIEGIFNQSLPEGGYEEVIQIPKGSVHIDIRELNLSINYLALRGDAGEYYINGKLSIDPPRRFDIAGTTFHYRRSPDEPESLEALGPTNVTLFVMVLVRTELQGIRYKFNAPISRDASNQYSWHYTPWTKCSVLCAGGSQIQSVVCRKLSDSSTVSNHFCSPETKMLERQRPCNTEPCAPAWVIGNWSECSRSCNEGVRTRSVFCKRKISATEEKTLDDASCTQPRPKMLEPCNNQTCPPEWVALDWSECTPSCGPGFRHRIVLCKSGDHSATLPTSQCPEGSKPPTSMRCNLRRCPPPRWVTGEWGECSAHCGLGQQRRSVQCLAHTGQPSSDCLETLQPPGMQQCETKCESGPTDNPEECKDVNKVAYCPLVLKFKFCSRTYFRQMCCKTCQGH", "length": 1109 }, "evidence": [ { "id": "E1BMV7", "url": "https://omabrowser.org/oma/group/E1BMV7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A286ZY25-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 10", "gene_name": "ADAMTS10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPACQILRWALALGLGLAFKVTHTFRSQDEFLSSLESYEIAFPTRVDHNGALLAFPPAPRRQRRGTGPQAESRLFYKVAAPSTHFLLNLTRSPRLLAGHVSVEYWTREGLAWQRAARSHCLYAGHLQGQAGSSHVAISTCGGLHGLIVADEEEYLIEPLQGGPQRHRGPEDSGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNRSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDVREDKCRVCGGDGSACETIEGVFSPALLGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQTQSLEALGPINASLIVMVLARTELPTLRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQAVECRSQLDSSAVAPHHCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPACPPEWAALDWSECTPSCGPGLRHRVVLCKSADQRATLPPAHCAPAAKPPATMRCNLRRCPPARWVTGEWGECSAQCGFGQQQRPVRCSSHTGQPSRECAEALRPPATQQCEAKCDSTPAGDSLEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCHGR", "length": 1102 }, "evidence": [ { "id": "E1BMV7", "url": "https://omabrowser.org/oma/group/E1BMV7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MIE7-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 10", "gene_name": "Adamts10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASACQILRWALALGLGLTFKVTHAFRSQDELLSSLESYEIAFPTRVDHNGAMLAFSPPALRRQRRGTGATSESRLFYKVAAPSTHFLLNLTRSPRLLAGHVSVEYWTREGLAWQRAARAHCLYAGHLQGQAGSSHVAISTCGGLHGLIVAGEEEYLIEPLQGGPKGRRGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNMVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVSHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNGCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRSCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPALPGNGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPHPHRLPLAGTTFHLRQGPDQAQSLEALGPINASLIVMVLAQAELPALRYRFNAPIARDALPPYSWHYAPWSKCSAQCAGGSQVQVVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACQGPMCPPEWAALEWSECTPSCGPGLRHRVVLCKSADQRSTLPPGHCPPSAKPPATMRCNLRRCPPARWVASEWGECSSQCGLGQQQRTVRCTSHTGQPSRECTEALRPSTMQQCEAKCDSVVPPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR", "length": 1104 }, "evidence": [ { "id": "E1BMV7", "url": "https://omabrowser.org/oma/group/E1BMV7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M1NG56-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1", "gene_name": "adamts10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METVWRSLACVGIMAMVASGGAESWSDEKFAQSQAEFLSSLGQYEIAIPVRVGPHGETLSEEETSHGTVRHRRSTETQSAPEPQLYYQLSTSSTDLLLNLTLQGGLLSRQFRVEYWKRGRLAWSHPYLPSCHYVGHLQHQPHSSSVALSNCNGLQGVIVAGGEEYLIEPLVSAKNLTNEDGREGRPHVVYKRSSLRYQNMDQSCGVIDEKPGKSYGWWQRTIKPSPNQMGRGQLPLKRSVSRERFVETLVVADKMMVSYHGRRDIEQYILAVMNIVAKLFQDSSLGNAVNIVVTRLILLMEDQPTLEVNHHAGKSLDSFCKWQKSILHRNGHGNAIPDNGIAHHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCEPERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNACGVRSQETAKLMAAHITMKTNPFVWSACSRDYITNFLDSGMGSCLNNVPPKQEFVYPTTAPGQAYDADEQCRFQYGVKSRQCKYGEVCSELWCMSKGNRCITSSIPAAEGTICQTSTIEKGWCYKRLCVPYGTRPEGVDGGWGHWSPWEECSRTCGGGVSSSIRHCDSPRPTVGGKYCLGERKRFRSCNIDECPVGSQDFREIQCSDFDSVPFRGKFYTWKPYRGGGVKSCSLNCLAEGYNFYTERAPAVVDGTPCRDDSLDVCVNGECKHVGCDRILGSDVREDRCRVCGGDGSSCQVIEGVFNDSLSEGGYEEVVRIPKGSVFIHIQELNISLNYLVLKSKGDQYFINGKLTIDTPRRFDIAGGTFHYRRPANEPETLEALGPTNMTLIVMVLVREENPGILYRFNPPVSRDPLSSYSWHYTSWSRCSALCAGGVQVQQVVCKKQADLSVVYNHFCDKKNKPKDKKRPCNQEPCPPTWWTGDWSECSRSCNGGVRTREVLCKRKMSVTEEKVLDDTACTTTRPSVTEPCNNHTCPPEWHALDWSECTPGCGPGYRYRVILCRSGDNGETLPESECPKQSRPTTRVRCNIQRCPPPQWVAGPWGECSARCGMGQEIRFVQCLTHTGQPSNECPESHRPAFMQQCKSKCDHSGPTDNPEECKDVNTVAYCPLVLRFKFCGRAYFRQMCCKTCQGH", "length": 1108 }, "evidence": [ { "id": "E1BMV7", "url": "https://omabrowser.org/oma/group/E1BMV7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P58459-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 10", "gene_name": "Adamts10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASACQILRWALALGLGLTFKVTHAFRSQDELLSSLESYEIAFPTRVDHNGAMLAFSPPAFRRQRRGAGATTESRLFYKVAAPSTHFLLNLTRSPRLLAGHVSVEYWTREGLAWQRAARAHCLYAGHLQGQAGSSHVAVSTCGGLHGLIVADDEEYLIEPLQGGPKGHRGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNESERGQLGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVSHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNGCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRSCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTNDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPALPGTGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFHLRQGPDQAQSLEALGPINASLIIMVLAQAELPALHYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQVVECRNQLDSSAVAPHYCSGHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACQGPMCPPEWATLDWSECTPSCGPGLRHRVVLCKSADQRSTLPPGHCLPAAKPPSTMRCNLRRCPPARWVTSEWGECSTQCGLGQQQRTVRCTSHTGQPSRECTEALRPSTMQQCEAKCDSVVPPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR", "length": 1104 }, "evidence": [ { "id": "E1BMV7", "url": "https://omabrowser.org/oma/group/E1BMV7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H324-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 10", "gene_name": "ADAMTS10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPACQILRWALALGLGLMFEVTHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPPPRRQRRGTGATAESRLFYKVASPSTHFLLNLTRSSRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQASTSHVAISTCGGLHGLIVADEEEYLIEPLHGGPKGSRSPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGSTVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSVNEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCHGH", "length": 1103 }, "evidence": [ { "id": "E1BMV7", "url": "https://omabrowser.org/oma/group/E1BMV7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "E1BMV7", "url": "https://www.uniprot.org/uniprotkb/E1BMV7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BMV7", "url": "https://www.uniprot.org/uniprotkb/E1BMV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BMV7", "url": "https://www.uniprot.org/uniprotkb/E1BMV7" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "E1BMV7", "url": "https://www.uniprot.org/uniprotkb/E1BMV7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "E1BMV7", "url": "https://www.uniprot.org/uniprotkb/E1BMV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 740, "end_pos": 742, "annotation": "n_glycosylation_sequon" }, { "start_pos": 795, "end_pos": 797, "annotation": "n_glycosylation_sequon" }, { "start_pos": 892, "end_pos": 894, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMV7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1103, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMV7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMV7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMV7" }, { "id": "PS50900", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50900" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLAC", "eco_id": "ECO_0000259", "start_pos": 1065, "end_pos": 1103, "start_aa": "Gly", "end_aa": "Arg", 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BMY1-1", "uniprot_ac": "E1BMY1", "uniprot_id": "E1BMY1_BOVIN", "mass": { "chemical_mass": 14965.0, "monoisotopic_mass": 14965.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "type": "recommended", "evidence": [ { "id": "E1BMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY1/entry#names_and_taxonomy" } ] }, { "name": "Complex I-B15", "type": "synonym", "evidence": [ { "id": "E1BMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY1/entry#names_and_taxonomy" } ] }, { "name": "NADH-ubiquinone oxidoreductase B15 subunit", "type": "synonym", "evidence": [ { "id": "E1BMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.", "evidence": [ { "database": "UniProtKB", "id": "E1BMY1", "url": "https://www.uniprot.org/uniprotkb/E1BMY1#function" }, { "database": "UniProtKB", "id": "ARBA00003195", "url": "https://www.uniprot.org/uniprotkb/ARBA00003195#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMY1", "url": "https://www.uniprot.org/uniprotkb/E1BMY1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BMY1", "locus": {} } ], "crossref": [ { "id": "E1BMY1", "url": "https://alphafold.ebi.ac.uk/entry/E1BMY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000033335", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000033335", 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"Protein Classification", "Other" ] }, { "id": "NP_001377063", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377063", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BMZ1", "url": "https://www.uniprot.org/uniprotkb/E1BMZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMZ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAVNHSRVSEFVLLGLTDSPQLQIFLFVMFSVFCLMTMLGNCLILLTVLSTPHLHSPMYFLLSNLSLIDMCLSSFATPKMIMDFFAQHKTISFEGCISQIFFLHLFTGTEIVLLISMSFDRYIAICKPLHYSSIMSQRVCVGLVATSWTVGFLHTMSQLAFTLYLPFCGPNVVDSFFCDLPLVIQLACIDIYVLGIFMISTSGVIALVSFLFLLTSYITVLVTIKDHSSTGSTKAFSTCTAHFIVVLMFFGPCIFIYVWPFTDFLVDKVLSVFYTIFTPFLNPLIYTLRNQEVKTAVKKKLSNQYLNLGKTTPIYSVQ", "length": 319, "header": "tr|E1BMZ1-1|E1BMZ1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4K6 PE=3 SV=1 CANONICAL=E1BMZ1-1" }, "isoforms": [ { "isoform_ac": "E1BMZ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMZ1/entry#E1BMZ1-1", "sequence": { "sequence": "MEAVNHSRVSEFVLLGLTDSPQLQIFLFVMFSVFCLMTMLGNCLILLTVLSTPHLHSPMYFLLSNLSLIDMCLSSFATPKMIMDFFAQHKTISFEGCISQIFFLHLFTGTEIVLLISMSFDRYIAICKPLHYSSIMSQRVCVGLVATSWTVGFLHTMSQLAFTLYLPFCGPNVVDSFFCDLPLVIQLACIDIYVLGIFMISTSGVIALVSFLFLLTSYITVLVTIKDHSSTGSTKAFSTCTAHFIVVLMFFGPCIFIYVWPFTDFLVDKVLSVFYTIFTPFLNPLIYTLRNQEVKTAVKKKLSNQYLNLGKTTPIYSVQ", "length": 319, "header": "tr|E1BMZ1-1|E1BMZ1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4K6 PE=3 SV=1 CANONICAL=E1BMZ1-1" }, "locus": { "chromosome": "10", "start_pos": 27235015, "end_pos": 27234059, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039095.3", "url": "https://www.ensembl.org/id/ENSBTAT00000039095.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038896.2", "url": "https://www.ensembl.org/id/ENSBTAP00000038896.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], 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"name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377073" }, "gene_names": [ { "name": "OR13C7B", "type": "recommended", "evidence": [ { "id": "E1BMZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMZ6" } ] }, { "name": "OR13C7B", "type": "synonym", "evidence": [ { "id": "NP_001377073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377073" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BMZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMZ6/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 13C7", "type": "synonym", "evidence": [ { "id": "NP_001377073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377073" } ] }, { "name": "olfactory receptor family 13 subfamily C member 7B", "type": "synonym", "evidence": [ { "id": "NP_001377073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377073" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ6", "url": "https://www.uniprot.org/uniprotkb/E1BMZ6#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377073" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ6", "url": "https://www.uniprot.org/uniprotkb/E1BMZ6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMZ6", "url": "https://www.uniprot.org/uniprotkb/E1BMZ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR13C7B", "url": "https://www.uniprot.org/uniprotkb/E1BMZ6", "locus": { "chromosome": "8", "start_pos": 60286972, "end_pos": 60287928, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000062753", "url": "https://www.ensembl.org/id/ENSBTAG00000062753" } ] } } ], "crossref": [ { "id": "E1BMZ6", "url": "https://alphafold.ebi.ac.uk/entry/E1BMZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000051473", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000051473", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15430", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15430", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532403", "url": "https://www.ncbi.nlm.nih.gov/gene/532403", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532403", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532403", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DNIVNHF", "url": "https://omabrowser.org/oma/group/DNIVNHF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMZ6", "url": "https://www.orthodb.org/?gene=E1BMZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377073", "database": "RefSeq", 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Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.", "evidence": [ { "database": "UniProtKB", "id": "E1BN00", "url": "https://www.uniprot.org/uniprotkb/E1BN00#function" }, { "database": "UniProtKB", "id": "O60928", "url": "https://www.uniprot.org/uniprotkb/O60928#function" } ] }, { "annotation": "The activity of Kir channels in the RPE is critically dependent on the regeneration of membrane PIP2 by PI4 kinases and that this may explain the dependence of these channels on hydrolyzable ATP.", "evidence": [ { "database": "RefSeq", "id": "NP_001180183", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180183" }, { "database": "PubMed", "id": "19641096", "url": "https://glygen.org/publication/PubMed/19641096" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN00", "url": "https://www.uniprot.org/uniprotkb/E1BN00" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KCNJ13", "url": "https://www.uniprot.org/uniprotkb/E1BN00", "locus": { "chromosome": "3", "start_pos": 112513605, "end_pos": 112520990, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005858", "url": "https://www.ensembl.org/id/ENSBTAG00000005858" } ] } } ], "crossref": [ { "id": "E1BN00", "url": "https://alphafold.ebi.ac.uk/entry/E1BN00", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005858", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005858", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "512288", "url": "https://www.ncbi.nlm.nih.gov/gene/512288", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008062", "url": 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Pathway" ] }, { "id": "QGQTCLM", "url": "https://omabrowser.org/oma/group/QGQTCLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN00", "url": "https://www.orthodb.org/?gene=E1BN00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01007", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01007", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17655", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17655", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180183", "url": 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GN=KCNJ13 PE=1 SV=1 CANONICAL=E1BN00-1" }, "isoforms": [ { "isoform_ac": "E1BN00-1", "url": "https://www.uniprot.org/uniprotkb/E1BN00/entry#E1BN00-1", "sequence": { "sequence": "MDGSHCKVIAPLLTERHQRMVTKDGHSTLQMDGAQTGLAYLRDAWGILMDMRWRWMMLVFSASFVIHWLVFAVLWYILAEMNGDLGLDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDLAVVAHIDGKPNLIFQVANTRPSPLTNVRVSAVLYQERENGKLYQTSVDFHLDGISSEECPFFIFPLTYYHSIIPSSPLATLLQHENPPHFELVVFLSAMQEGTGETCQRRTSYLPSEIMLHHCFASLLARGSKGEYQIKMENFDKTTPEFQTPLVSKSPNRTDLDIHINGQSIDNFQISETGLTE", "length": 360, "header": "sp|E1BN00-1|KCJ13_BOVIN Isoform 1 of Inward rectifier potassium channel 13 OS=Bos taurus OX=9913 GN=KCNJ13 PE=1 SV=1 CANONICAL=E1BN00-1" }, "locus": { "chromosome": "3", "start_pos": 112516159, "end_pos": 112513882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007700.5", "url": "https://www.ensembl.org/id/ENSBTAT00000007700.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007700.3", "url": "https://www.ensembl.org/id/ENSBTAP00000007700.3" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 287, "end_pos": 287, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "E1BN00", "url": "https://www.uniprot.org/uniprotkb/E1BN00" } ], "site_lbl": "Ser287" } ], "glycation": [], "keywords": [], "publication": [ { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "E1BN00", "url": "https://www.uniprot.org/uniprotkb/E1BN00" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] }, { "title": "Regulation of Kir channels in bovine retinal pigment epithelial cells by phosphatidylinositol 4,5-bisphosphate.", "journal": "American journal of physiology. Cell physiology", "date": "2009-10", "authors": "Pattnaik Bikash R, Hughes Bret A", "evidence": [ { "database": "RefSeq", "id": "NP_001180183", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180183" } ], "reference": [ { "type": "PubMed", "id": "19641096", "url": "https://glygen.org/publication/PubMed/19641096" } ] }, { "title": "The small GTPase RAB28 is required for phagocytosis of cone outer segments by the murine retinal pigmented epithelium.", "journal": "J. Biol. Chem.", "date": "2018", "authors": "Ying G, Boldt K, Ueffing M, Gerstner CD, Frederick JM, Baehr W", "evidence": [ { "database": "UniProtKB", "id": "E1BN00", "url": "https://www.uniprot.org/uniprotkb/E1BN00" } ], "reference": [ { "type": "PubMed", "id": "30228185", "url": "https://glygen.org/publication/PubMed/30228185" } ] } ], "pathway": [ { "id": "bta:512288", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512288", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IC55-1", "protein_name": "Inward rectifier potassium channel 13", "gene_name": "Kcnj13", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDNSNCKVNAPLLSQRYRRMVTKDGHSTLQMEGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYVLAEMNGDLEIDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDLAVVAHKDGKPNLMFQVANTRPSPLTSVRVSAVLYQERENGELYQTSVDFHLDGISSEECPFFIFPLTYYHTIIPSSPLATLLQHENLPHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHHFAALITRGSKGEYQVKMENFDKTVPEHPTPVVSKSPHRTGLDIHINGQSIDNFQISETGLTE", "length": 360 }, "evidence": [ { "id": "E1BN00", "url": "https://omabrowser.org/oma/group/E1BN00/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0ZXM0-1", "protein_name": "Inward rectifier potassium channel 13", "gene_name": "KCNJ13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRTDTTESNNTKSSTPLLTQRYLRMVTKDGHSTFQMDGAQGQGLAYLRDAWGILMDMRWRWMMLVFSASFVIHWLVFAVLWYVLAEMNGDLELDHDSPPDNHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIALLAIQMVLGLMLEAFITGAFVAKIARPKNRAFSIRFTRSAVVTHTEGKPYLMFQVANTRSSPLTSVQISAILYQEQENGQLHQTSIDFHLDSITLDECPFFTFPLTYYHSIIPPSPLAALLQREAAHHFELVVFLSAVQEGTGEICQRRTSYLPSEIMLYHRFAPVLARSAKGEYQIKMENFDKTIPELPAAADSMNPMRTAKEIRINGQHVDSFQLSETGLTE", "length": 366 }, "evidence": [ { "id": "E1BN00", "url": "https://omabrowser.org/oma/group/E1BN00/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LPQ3-1", "protein_name": "Inward rectifier potassium channel 13", "gene_name": "KCNJ13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGSNCKVIAPLLTRRYRRIVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYILAEMNGDLELDHDAPPGNHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDLAVVAHIDGKPNLIFQVANTRPSPLTSVRVSAVLYQERENGELYQTSVDFHLDGISSEECPFFIFPLTYYHSITPSSPLATLLQQENPPHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEYQIKMDNFDKTIPELPTPLVSKTPNRTDLDIHINGQSIDNFQISETGLTE", "length": 360 }, "evidence": [ { "id": "E1BN00", "url": "https://omabrowser.org/oma/group/E1BN00/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O60928-1", "protein_name": "Inward rectifier potassium channel 13", "gene_name": "KCNJ13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSSNCKVIAPLLSQRYRRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPSPLTSVRVSAVLYQERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSPLATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEYQIKMENFDKTVPEFPTPLVSKSPNRTDLDIHINGQSIDNFQISETGLTE", "length": 360 }, "evidence": [ { "id": "E1BN00", "url": "https://omabrowser.org/oma/group/E1BN00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70617-1", "protein_name": "Inward rectifier potassium channel 13", "gene_name": "Kcnj13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSRNCKVNAPLLSQRYRRMVTKDGHSTLQMDGAQRGLVYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYAVAEMNGDLEIDHDVPPENHTICVKHITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDLAVVAHKDGKPNLIFQVANTRPSPLTSVRVSAVLYQERENGELYQTSVDFHLDGISSEECPFFIFPLTYYHTITPSSPLATLLQHETPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHRFAALMTRGSKGEYQVKMENFDKTVPEHPTPVVSKSPHRTDLDIHINGQSIDNFQIAETGLTE", "length": 360 }, "evidence": [ { "id": "E1BN00", "url": "https://omabrowser.org/oma/group/E1BN00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P86046-1", "protein_name": "Inward rectifier potassium channel 13", "gene_name": "Kcnj13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSNCKVNAPLLSQRHRRMVTKDGHSTLQMDGAQRGLVYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYAVAEMNGDLEIDHDVPPENHTICVKHITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDLAVVAHKDGKPNLIFQVANTRPSPLTNVRVSAVLYQERENGELYQTSVDFHLDGISSEECPFFIFPLTYYHTISPSSPLATLLQHETPPHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHRFAALMTRGSKGEYQVKMENFDKTVPEHPTPVVSKSPHRTDLDIHINGQSIDNFQIAETGLTE", "length": 360 }, "evidence": [ { "id": "E1BN00", "url": "https://omabrowser.org/oma/group/E1BN00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BN00", "url": "https://www.uniprot.org/uniprotkb/E1BN00" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "E1BN00", "url": "https://www.uniprot.org/uniprotkb/E1BN00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "E1BN00", "url": "https://www.uniprot.org/uniprotkb/E1BN00" } ], "pmid": "" }, { "name": "potassium ion import across plasma membrane", "id": "GO:1990573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990573", "evidence": [ { "database": "UniProtKB", "id": "E1BN00", "url": "https://www.uniprot.org/uniprotkb/E1BN00" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "inward rectifier potassium channel activity", "id": "GO:0005242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005242", "evidence": [ { "database": "UniProtKB", "id": "E1BN00", "url": "https://www.uniprot.org/uniprotkb/E1BN00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35526-1" ], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN00-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 360, "overlap": "1.0", "method": "AlphaFold", 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}, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1BN09-1", "uniprot_ac": "E1BN09", "uniprot_id": "E1BN09_BOVIN", "mass": { "chemical_mass": 35188.0, "monoisotopic_mass": 35188.0 }, "refseq": { "ac": "NP_001377091", "name": "olfactory receptor family 2 subfamily H member 1", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377091" }, "gene_names": [ { "name": "OR2H1", "type": "recommended", "evidence": [ { "id": "E1BN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN09" } ] }, { "name": "OR2H1", "type": "synonym", "evidence": [ { "id": "NP_001377091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377091" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN09/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 2 subfamily H member 1", "type": "synonym", "evidence": [ { "id": "NP_001377091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377091" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377091", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377091" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BN09", "url": "https://www.uniprot.org/uniprotkb/E1BN09#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN09", "url": "https://www.uniprot.org/uniprotkb/E1BN09" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2H1", "url": "https://www.uniprot.org/uniprotkb/E1BN09", "locus": { "chromosome": "23", "start_pos": 29102226, "end_pos": 29103164, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000027245", "url": "https://www.ensembl.org/id/ENSBTAG00000027245" } ] } } ], "crossref": [ { "id": "E1BN09", "url": "https://alphafold.ebi.ac.uk/entry/E1BN09", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000027245", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000027245", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538947", "url": "https://www.ncbi.nlm.nih.gov/gene/538947", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538947", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538947", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAIAWAV", "url": "https://omabrowser.org/oma/group/CAIAWAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN09", "url": "https://www.orthodb.org/?gene=E1BN09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377091", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377091", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BN09", "url": "https://www.uniprot.org/uniprotkb/E1BN09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN09-1", "url": "https://www.uniprot.org/uniprotkb/E1BN09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVNHSFPVDFLLLGFSEHPGLERILFMVVSISYLLTLVGNTLIILLSMLDPRLHSPMYFFLSNLSFLDLCFTTSCVPQMLVHLWGPRKTISFLGCSVQLFIFLFLGTTECVLLTVMAFDRYVAVCQPLHYATIIHPRLCWQLAAVAWVMGLVQSVVQTPPTLRLPFCPHRQIDDFACEVPSLIQLSCGDTTYNEIQLAVSSFIFLVMPLTLILISYGSIAWAVLRINSAIAWRKALGTCSSHLIVITLFYSLVIAVYLQPKNPYAQKRGKFFGLFYAVGTPLLNPLIYSLRNKEVKGALRRLLGKDKDSREN", "length": 312, "header": "tr|E1BN09-1|E1BN09_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2H1 PE=3 SV=2 CANONICAL=E1BN09-1" }, "isoforms": [ { "isoform_ac": "E1BN09-1", "url": "https://www.uniprot.org/uniprotkb/E1BN09/entry#E1BN09-1", "sequence": { "sequence": "MVNHSFPVDFLLLGFSEHPGLERILFMVVSISYLLTLVGNTLIILLSMLDPRLHSPMYFFLSNLSFLDLCFTTSCVPQMLVHLWGPRKTISFLGCSVQLFIFLFLGTTECVLLTVMAFDRYVAVCQPLHYATIIHPRLCWQLAAVAWVMGLVQSVVQTPPTLRLPFCPHRQIDDFACEVPSLIQLSCGDTTYNEIQLAVSSFIFLVMPLTLILISYGSIAWAVLRINSAIAWRKALGTCSSHLIVITLFYSLVIAVYLQPKNPYAQKRGKFFGLFYAVGTPLLNPLIYSLRNKEVKGALRRLLGKDKDSREN", "length": 312, "header": "tr|E1BN09-1|E1BN09_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2H1 PE=3 SV=2 CANONICAL=E1BN09-1" }, "locus": { "chromosome": "23", "start_pos": 29103164, "end_pos": 29102229, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039058.5", "url": "https://www.ensembl.org/id/ENSBTAT00000039058.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038862.4", "url": "https://www.ensembl.org/id/ENSBTAP00000038862.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538947", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538947", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "L7N475-1", "protein_name": "Olfactory receptor", "gene_name": "Or2h2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNQSSPVVFFLLGFSDNPQLEKVLFVVVLCSYLLTLLGNTLILLLSTLDPRLHSPMYFFLSNLSFLDLCFTTTCVPQMLFNLWGPAKTISFLGCFVQLFIFMSLGTTECILLTVMAFDRYVAVCQPLHYATKINPHLCRQLAGIAWAIGLVQSIVQTPPTLKLPFCSHRQIDNFLCEVPSLIQLSCGDTTYNEIQMAVASIFIVVVPLSLILVSYGAIARAVLKISSAKGRRKAFGTCSSHLIVVTLFYSSVIAVYLQPKNLYARERGKFFGLFYAVGTPTLNPLVYTLRNKEVKRAFWKLLRKDEDSEES", "length": 312 }, "evidence": [ { "id": "E1BN09", "url": "https://omabrowser.org/oma/group/E1BN09/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6MFX4-1", "protein_name": "Olfactory receptor", "gene_name": "Or2h2c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNQSSPTGFLLLGFSEHPHLEKILFVVVLCSYLLTLLGNTLILLLSTLDPRLHSPMYFFLSNLSFLDLCFTTTCVPQMLVNLWGPTKTISFLGCSVQLFIFMSLGTTECILLTVMAFDRYVAVCRPLHYATIIHPRLCRQLAGVAWAIGLVQSTVQTPPTLHLPFCPHRQIDNFLCEVPSLIRLSCGDTTFNEIQMAVASVFIVVVPLSLILVSYGAIARAVLRIRSAKGRRKAFGTCSSHLIVVTLFYSSVIAVYLQPKNPYAQERGKFFGLFYAVGTPTLNPLVYTLRNKEVKRAFWKLLGKDGDSEES", "length": 312 }, "evidence": [ { "id": "E1BN09", "url": "https://omabrowser.org/oma/group/E1BN09/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9GZK4-1", "protein_name": "Olfactory receptor 2H1", "gene_name": "OR2H1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNQSSPMGFLLLGFSEHPALERTLFVVVFTSYLLTLVGNTLIILLSVLYPRLHSPMYFFLSDLSFLDLCFTTSCVPQMLVNLWGPKKTISFLGCSVQLFIFLSLGTTECILLTVMAFDRYVAVCQPLHYATIIHPRLCWQLASVAWVMSLVQSIVQTPSTLHLPFCPHQQIDDFLCEVPSLIRLSCGDTSYNEIQLAVSSVIFVVVPLSLILASYGATAQAVLRINSATAWRKAFGTCSSHLTVVTLFYSSVIAVYLQPKNPYAQGRGKFFGLFYAVGTPSLNPLVYTLRNKEIKRALRRLLGKERDSRESWRAA", "length": 316 }, 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809688" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN10", "url": "https://www.uniprot.org/uniprotkb/E1BN10" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MYT1", "url": "https://www.uniprot.org/uniprotkb/E1BN10", "locus": { "chromosome": "13", "start_pos": 53683235, "end_pos": 53718117, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006352", "url": "https://www.ensembl.org/id/ENSBTAG00000006352" } ] } } ], "crossref": [ { "id": "E1BN10", "url": "https://alphafold.ebi.ac.uk/entry/E1BN10", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006352", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006352", 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"GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 798, "start_aa": "Thr", "end_pos": 798, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr798", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 842, "start_aa": "Thr", "end_pos": 842, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr842", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 944, "start_aa": "Thr", "end_pos": 944, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr944", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BN10", "url": "https://www.uniprot.org/uniprotkb/E1BN10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BN10", "url": "https://www.uniprot.org/uniprotkb/E1BN10" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BN10", "url": "https://www.uniprot.org/uniprotkb/E1BN10" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BN10", "url": "https://www.uniprot.org/uniprotkb/E1BN10" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BN10", "url": "https://www.uniprot.org/uniprotkb/E1BN10" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BN10", "url": "https://www.uniprot.org/uniprotkb/E1BN10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1011, "end_pos": 1013, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" }, { "start_pos": 662, "end_pos": 664, "annotation": "n_glycosylation_sequon" }, { "start_pos": 926, "end_pos": 928, "annotation": "n_glycosylation_sequon" }, { "start_pos": 954, "end_pos": 956, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN10-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1121, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN10-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN10" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN10" }, { "id": "PF08474", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08474" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myelin transcription factor 1", "eco_id": "ECO_0000259", "start_pos": 535, "end_pos": 786, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 32, 463, 542, 798, 842, 944 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1011, "end_pos": 1013 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 642, "end_pos": 644 }, { "start_pos": 662, "end_pos": 664 }, { "start_pos": 926, "end_pos": 928 }, { "start_pos": 954, "end_pos": 956 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 6 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 6 }, { "field": "exact_o_linked_sites", "count": 6 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BN24-1", "uniprot_ac": "E1BN24", "uniprot_id": "E1BN24_BOVIN", "mass": { "chemical_mass": 219979.0, "monoisotopic_mass": 219979.0 }, "refseq": { "ac": "NP_001192645", "name": "NFX1-type zinc finger-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192645" }, "gene_names": [ { "name": "ZNFX1", "type": "recommended", "evidence": [ { "id": "E1BN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ] }, { "name": "ZNFX1", "type": "synonym", "evidence": [ { "id": "NP_001192645", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192645" } ] } ], "protein_names": [ { "name": "NFX1-type zinc finger-containing protein 1", "type": "recommended", "evidence": [ { "id": "E1BN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN24/entry#names_and_taxonomy" } ] }, { "name": "NFX1-type zinc finger-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001192645", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192645" } ] } ], "function": [ { "annotation": "RNA-binding protein that initiates the antiviral response and is required to restrict the replication of RNA viruses. Acts as a double-stranded RNA (dsRNA) sensor that recognizes viral RNA and then interacts with MAVS to initiate the type I interferon response. 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"id": "ENSBTAG00000020166", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020166", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06008", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06008", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18808", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18808", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539807", "url": "https://www.ncbi.nlm.nih.gov/gene/539807", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539807", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539807", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PVCQVPI", "url": "https://omabrowser.org/oma/group/PVCQVPI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN24", "url": "https://www.orthodb.org/?gene=E1BN24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10887", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10887", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10887:SF341", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10887:SF341", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20173", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20173", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25396", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25396", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192645", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192645", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN24-1", "url": "https://www.uniprot.org/uniprotkb/E1BN24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDRRPCPEVGPRNPHINHRGPMDGELPPRARNQANNPPANALRGGASQPRRHPRANSHPFPHRQREERFGAMGGNPHQGRRNQEGHANDEPRGQRHGQENDTRRRNGNQEGRNRRPPPRSDENFQQWRTPHQKPAEQPQQVKKLGYKFLESLLQKDSSEVVITLATCSGLQELLSHSFMKSDFLELICQVLRKACSSKMDRHSVLHILGILKNSKFLKVCLPAYVVGMITEPLPEVRNQYPKHISNIISLLQDLVSVFPASSVQETSMLISLLPASLNALRASGVNIEEETEKNLEKVQTIIEHLQEKRREGTLKVDTYTLVQPKAEDHVESYRTMPIYPTYNEVHLDEKPFLRPNIISGKYESTAVYLDTHFRLLREDFVRPLREGILELLQSFEDQGLRKRKFDDIRIYFDTRIITPVCSSTGIVYKVQFDTKPLKFVRWQNSKRLLYGSLVCMSKDNFETFLFATVSNREQEDLCRGIVQLSFNEQSQQLLADVQPSDSFLMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVECDSDVREPRYLLMGGRYDFTPLIKNPSATGEPLRNDEGLRHPRVNVLDPCQWPSKEALRLDDSQMEALRFALTRELAIIQGPPGTGKTYVGLKIVQALLTNEPVWQISVQKFPILVVCYTNHALDQFLEGIYKCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRNLPLHLRRAYMSIMTQMKESEQELHEGAQTLECTMRGVLQEQHLEKFISPQHWKSLMNGPNQDSEWVCFRGRKHSVMLEFLGLGVGSFTQSVAPAVPENTAQAEREEEEEEGEEDGSLIEIAEEADLIQADRMIEEEELARPRRRRKEENGAIQELAEVLLAMRLDNHGPGTAAGQEQATGEWETQRSQKKRMKKKVKVELRKLNTMTEAEANKIQDVWQLDLNSRWQLYRLWLQMYQADTRRKILNYERQYRTSAERMAELRLQEDLHILKDAQIVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVRLNYQHRMRPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHTFPEQEIQEGRSHQNQHEARFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFAGVKVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAKVPLWSKIIHTLRENDQIGCALRLCCQNHPDTHTLVSKASDFQKVPEGGCSLPCEFRLGCGHVCTRACHPYDSSHKEFQCMKPCQKVICQDGHRCPLVCFQECQPCQVKVPKTILRCGHKQMVPCSVPESDFCCQEPCPKVLKCGHTCSHPCGEDCVWLCSEMVTVKLKCGHRQQMKCGNVEDLKHGLPVQCTTKCGSILDCGHPCPGSCHSCFEGRFHERCQQPCKRLLICSHKCQEPCTGECPPCQRICQNRCVHSQCKKKCGELCTPCMEPCIWRCRHYQCTRLCSEPCDRPPCYVPCTKLLACGHPCIGLCGEPCPKKCRVCHQEEVTQIFFGSEDEPDARFVQLEDCSHIFEVQALDRYMNEQGDEVAIRLKVCPICQVPIRKNLRYGTSLKQRLEEIEVVKEKILGSAGEIAVSQERLTALLEGKNLLCQELPEDFLKLEEKLAQKNLSVKDLGLVENYISFYDHLAGLYDSLKKVHVLEQEKVRTRLDQVHEWLAKKRLSFSSQELDDLQSEIQRLRYLVNLLTRCKMAEGKVRGSVAEEISTVRNILERTCKFTQKDAELVQRKMEALKAALPCSGLGISEEERVQIVKAMGYRRGHWFKCPNGHIYVIGDCGGAMQRAKCPECQEVIGGENHTLERSNRLASEMDGAQHPAWSDTANNMMNYEELQRMM", "length": 1918, "header": "tr|E1BN24-1|E1BN24_BOVIN Isoform 1 of NFX1-type zinc finger-containing protein 1 OS=Bos taurus OX=9913 GN=ZNFX1 PE=3 SV=2 CANONICAL=E1BN24-1" }, "isoforms": [ { "isoform_ac": "E1BN24-1", "url": "https://www.uniprot.org/uniprotkb/E1BN24/entry#E1BN24-1", "sequence": { "sequence": "MEDRRPCPEVGPRNPHINHRGPMDGELPPRARNQANNPPANALRGGASQPRRHPRANSHPFPHRQREERFGAMGGNPHQGRRNQEGHANDEPRGQRHGQENDTRRRNGNQEGRNRRPPPRSDENFQQWRTPHQKPAEQPQQVKKLGYKFLESLLQKDSSEVVITLATCSGLQELLSHSFMKSDFLELICQVLRKACSSKMDRHSVLHILGILKNSKFLKVCLPAYVVGMITEPLPEVRNQYPKHISNIISLLQDLVSVFPASSVQETSMLISLLPASLNALRASGVNIEEETEKNLEKVQTIIEHLQEKRREGTLKVDTYTLVQPKAEDHVESYRTMPIYPTYNEVHLDEKPFLRPNIISGKYESTAVYLDTHFRLLREDFVRPLREGILELLQSFEDQGLRKRKFDDIRIYFDTRIITPVCSSTGIVYKVQFDTKPLKFVRWQNSKRLLYGSLVCMSKDNFETFLFATVSNREQEDLCRGIVQLSFNEQSQQLLADVQPSDSFLMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVECDSDVREPRYLLMGGRYDFTPLIKNPSATGEPLRNDEGLRHPRVNVLDPCQWPSKEALRLDDSQMEALRFALTRELAIIQGPPGTGKTYVGLKIVQALLTNEPVWQISVQKFPILVVCYTNHALDQFLEGIYKCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRNLPLHLRRAYMSIMTQMKESEQELHEGAQTLECTMRGVLQEQHLEKFISPQHWKSLMNGPNQDSEWVCFRGRKHSVMLEFLGLGVGSFTQSVAPAVPENTAQAEREEEEEEGEEDGSLIEIAEEADLIQADRMIEEEELARPRRRRKEENGAIQELAEVLLAMRLDNHGPGTAAGQEQATGEWETQRSQKKRMKKKVKVELRKLNTMTEAEANKIQDVWQLDLNSRWQLYRLWLQMYQADTRRKILNYERQYRTSAERMAELRLQEDLHILKDAQIVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVRLNYQHRMRPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHTFPEQEIQEGRSHQNQHEARFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFAGVKVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAKVPLWSKIIHTLRENDQIGCALRLCCQNHPDTHTLVSKASDFQKVPEGGCSLPCEFRLGCGHVCTRACHPYDSSHKEFQCMKPCQKVICQDGHRCPLVCFQECQPCQVKVPKTILRCGHKQMVPCSVPESDFCCQEPCPKVLKCGHTCSHPCGEDCVWLCSEMVTVKLKCGHRQQMKCGNVEDLKHGLPVQCTTKCGSILDCGHPCPGSCHSCFEGRFHERCQQPCKRLLICSHKCQEPCTGECPPCQRICQNRCVHSQCKKKCGELCTPCMEPCIWRCRHYQCTRLCSEPCDRPPCYVPCTKLLACGHPCIGLCGEPCPKKCRVCHQEEVTQIFFGSEDEPDARFVQLEDCSHIFEVQALDRYMNEQGDEVAIRLKVCPICQVPIRKNLRYGTSLKQRLEEIEVVKEKILGSAGEIAVSQERLTALLEGKNLLCQELPEDFLKLEEKLAQKNLSVKDLGLVENYISFYDHLAGLYDSLKKVHVLEQEKVRTRLDQVHEWLAKKRLSFSSQELDDLQSEIQRLRYLVNLLTRCKMAEGKVRGSVAEEISTVRNILERTCKFTQKDAELVQRKMEALKAALPCSGLGISEEERVQIVKAMGYRRGHWFKCPNGHIYVIGDCGGAMQRAKCPECQEVIGGENHTLERSNRLASEMDGAQHPAWSDTANNMMNYEELQRMM", "length": 1918, "header": "tr|E1BN24-1|E1BN24_BOVIN Isoform 1 of NFX1-type zinc finger-containing protein 1 OS=Bos taurus OX=9913 GN=ZNFX1 PE=3 SV=2 CANONICAL=E1BN24-1" }, "locus": { "chromosome": "13", "start_pos": 77372601, "end_pos": 77349804, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026859.4", "url": "https://www.ensembl.org/id/ENSBTAT00000026859.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026859.3", "url": "https://www.ensembl.org/id/ENSBTAP00000026859.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539807", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539807", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3L5Z9-1", "protein_name": "NFX1-type zinc finger-containing protein 1", "gene_name": "ZNFX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENRRPCLEARPRNPRINHRGPVDGELPPRARNQASNPPINALSGGANQHGRNPRANNHPVPHRQREERFGAMGRNPYQGRRNQEGHANEEPRGQRHGQENDTRRRNCNQEGRNCRPPRSDENFQQWRTPHQNPVEQPQQVKKLGYKFLESLLQKDPSEVVITLATSLGLRELLSHSSMKSNFLELICQVLRKACSSKMDRHSILHVLGILKNSQFLKVCLPAYVVGMITEPIPDVRNHYPEHISNIISLLQDLVSVFPASSVQETSMLISLLPASLNALRASGVDIEEETEKNLEKVQTIIEHLQEKRREGTLRVDTYTLVQPEVEDHVESYRNIPIYPTYNEVHLDERPFLRPNIISGKYDNTAVYLDTHFRLLREDFVRPLREGILELLQSFEDQGLRKRKFDDIRIYFDTRIITPVCSSSGIVYKVQFDTKPLKFVRWQNSKRLLYGSLVCMSKDNFETFLFATVSNREQEDLCRGIVQLSFNEQSQQLLAEVQPSDSFLMVETTAYFEAYRHVLEGLQEIQEEDVPFQRNIVECDSHVKEPRYLLMGGRYDFIPLIKDPSATGESLRNAKALRCSRVNVLDPSQWPSKEALKLDDSQMEALQFALTRELAIIQGPPGTGKTYVGLKIVQALLTNEPVWQISLQKFPILVVCYTNHALDQFLEGIYKCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRNLPMHLRRAYMSIMTQMKESEQELHEGAQTLECTMRGVLREQHLEKYISPQHWKSLMNGPVQDSEWVCFQGWKHSMMLEWLGLGVGSFTQNVTPPGPESTAQAEGEEEEEEGEEESSLIEIAEEADLIQADRVIEEEEVVRPRRRKKEENGAIQELAQELLAMRLDNLGPRTSAGQKQAAGEWETQRSQKKKMKKKVKVELRKLNTMTEAEASEIQDVWQLDLNSRWQLYRLWLQRYQADTRQKILGYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLEAHTITTLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVRLNYQHRMRPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHNFPEQEIQEGKSHQNQHEARFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFAGVRVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQIPNRICVALSRAKKGMYCVGNMQMLAKVPLWSRIIHTLRENNQIGSALRLCCQNHPDTHTLVSKASDFQTVPEGGCSLPCEFRLGCGHVCTRACHPYDSLHKEFQCMKPCQKVVCQDGHRCPLVCFQECQPCQVKVPKIILRCGHEQMVPCSMPESDFCCQEPCPKVLKCGHQCSNPCGEDCVRFCSEMVTVNLKCGHRQQVKCSSVDGLKYDMPVKCTTKCDTILDCGHPCPGSCHSCFEGRFHERCQQPCKRLLICSHKCQEPCIGECPPCQRTCQNRCVHSQCKKKCGELCSPCIEPCVWRCQHYQCTQLCSEPCDRPPCYVPCTKLLACGHPCIGLCGEPCPKKCRVCNQEEVTQIFFGSEDEPDARFVQLEDCSHIFEVQALDRYMNEQDNEVAIRLKVCPICQVPIRKNLRYGASIKQRLEEIEVVKKKIQGSAGEIAISQERLKALLEKKNLLCQLLPEDFLMLKEKLDQKNLSVKDLGLVENYISFYDHLASLWDSLKKVHVLEQERVSTRLNQIHDWLTKKRLSFTNQELDDLQSEIQRLTYLVDLLARCKTAGENVKGSVAGEVNSVRKILERTCKFTQEDEQLVQKKMEALKAILPRSGLGISEEERVQIVKAMGYPQGHWFKCPNGHIYAISDCGGAMQRARCPDCREVIGGVNHTLESSNQLASEMDGARHPAWSDTANNMLNFEEIRRLM", "length": 1917 }, "evidence": [ { "id": "E1BN24", "url": "https://omabrowser.org/oma/group/E1BN24/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8R151-1", "protein_name": "NFX1-type zinc finger-containing protein 1", "gene_name": "Znfx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDRRPHLEARPRNPPANHRGPMDGELPPRARNQTNNPAATNHAGRHLRASNHPAPFRQREERFRAMGRNPHQGRRNQEGHTSDEARDQRQSQNDTRRRNDDQEGRSHRPPWSSDTFQQWHTPPQKPGEQPQQTKRLGYKFLESLLQKEPSEVAITLATSLGLKELLSHSSMKPSFLQLICQVLRKACSSRIDRQSILHVLGILNNSKFLRVCLPAYVVGMITEPSPDIRNQYPEHISNIISLLQDLVSVFPASSMQETSMLISLLPTSLNALRASGVDIEEETEKNLEKVQAIIKYLQEKRRQGSLRVDTYTLVQAEAEGEVESYRAMPIYPTYNEVHLDEKPFLRPNIISGKYESTAVYLDTHFRLLREDFVRPLREGILKLLQSFEDQCLRKRKFDDIRIYFDARIITPMCSASGIVYKVQFDTKPLKLVRWQNSKRLLYGSLVCMSKDNFETFLFATVSNREHEDLCQGIVQLCFNEQSQQLLADVQPSDSFLMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVQCDSYVRNPRYLLMGGRYDFTPLMENPSAMRKSLRGAEALRHPRINVFDFGQWPSKEALKLDDSQMEALQFALTKELAIIQGPPGTGKTYVGLKIVQALLTNKSVWQINTQTFPILVVCYTNHALDQFLEGIYGCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRTLPMHLRRAYMSIVTEMKESEQKLQEGAQTLECTMHGVLREQHLEKYISAQHWESLMSGPVQDADWVCVQPSKHSMILEWLGLGVGSFTQSASPAGPENTAQAEGEEEEEGEEEGSLIEIAEEADLIQADRVIEEEEVVRPRRRKKEENGTDQELAKMLLAMRLDQEVPGTTAGPEQATEEWETQRGQKKKMKRRVKVELRKLNTMTKAEANGIQDVWQLDLSSRWQLYRLWLQMYQADTRRRILSYERQYRTWAERMAELRLQEDLHILKDAEVVGMTTTGAAKYRQILQQVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVRLNYQHRMRPEIARLLTPHIYQDLENHPSVLKYEQIKGVSSNLFFVEHNFPEQEIQEGKSHQNQHEAHFVVELCQYLLCQEYLPSQITILTTYTGQLFCLRKLMPVKTFAGIKVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQIPNRICVALSRAKKGMYCIGNMQMLAKVPLWSRIIHTLRENNQIGPSLRLCCQNHPETHTLVSKASDFQKVPEGGCSRPCEFRLACGHVCTRACHPYDSSHKEFQCMKPCQKVLCQDGHRCPNVCFQECQPCQVKVPKIILKCGHKQMVPCSMSESEFCCQEPCSKILRCGHRCSHLCGEDCVRLCSERVTVELKCGHSQLVKCGNVEDIKYGLPVKCTTKCDTTLDCGHPCPGSCHSCFEGRFHERCQQPCKRLLICSHKCQEPCTGECPPCQRTCQNRCVHSQCKKKCGELCSPCVEPCVWRCQHYQCTKLCSEPCNRPPCYVPCTKLLACGHPCIGLCGEPCPKKCRVCQPDEVTQIFFGFEDEPDARFVQLEDCSHIFEVQALDRFMNEQKDDEVAIKLKVCPICQVPIRKNLRYGTSIKQRLEEIEIVKEKIQGSAGEISTSQEQLKALLKSKTLFHQLRPEEFLILQEKLAQKNLSVKDLGLVENSIRFYDHLANLEGSLEKVHCGEQQSVRTRLEQVHEWLAKKRLSFSSQELSDLQSEIQRLTYLVNLLMRCKMAEKVKGSIAEEVSSIRNILEKTSKFTQEDEQLVQKKMDALKTTLPCSGLGISDEERVQIVTAMGVPRGHWFKCPNGHIYVITECGGAMQRSTCPECQEVIGGENHTLERSNHLASEMDGAQHPAWSNTANNFMNFEEIHRMM", "length": 1909 }, "evidence": [ { "id": "E1BN24", "url": "https://omabrowser.org/oma/group/E1BN24/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2E3-1", "protein_name": "NFX1-type zinc finger-containing protein 1", "gene_name": "ZNFX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEERRPHLDARPRNSHTNHRGPVDGELPPRARNQANNPPANALRGGASHPGRHPRANNHPAAYWQREERFRAMGRNPHQGRRNQEGHASDEARDQRHDQENDTRWRNGNQDCRNRRPPWSNDNFQQWRTPHQKPTEQPQQAKKLGYKFLESLLQKDPSEVVITLATSLGLKELLSHSSMKSNFLELICQVLRKACSSKMDRQSVLHVLGILKNSKFLKVCLPAYVVGMITEPIPDIRNQYPEHISNIISLLQDLVSVFPASSVQETSMLVSLLPTSLNALRASGVDIEEETEKNLEKVQTIIEHLQEKRREGTLRVDTYTLVQPEAEDHVESYRTMPIYPTYNEVHLDERPFLRPNIISGKYDSTAIYLDTHFRLLREDFVRPLREGILELLQSFEDQGLRKRKFDDIRIYFDTRIITPMCSSSGIVYKVQFDTKPLKFVRWQNSKRLLYGSLVCMSKDNFETFLFATVSNREQEDLCRGIVQLCFNEQSQQLLAEVQPSDSFLMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVECNSHVKEPRYLLMGGRYDFTPLIENPSATGEFLRNVEGLRHPRINVLDPGQWPSKEALKLDDSQMEALQFALTRELAIIQGPPGTGKTYVGLKIVQALLTNESVWQISLQKFPILVVCYTNHALDQFLEGIYNCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRNLPMHLRRAYMSIMTQMKESEQELHEGAKTLECTMRGVLREQYLQKYISPQHWESLMNGPVQDSEWICFQHWKHSMMLEWLGLGVGSFTQSVSPAGPENTAQAEGDEEEEGEEESSLIEIAEEADLIQADRVIEEEEVVRPQRRKKEESGADQELAKMLLAMRLDHCGTGTAAGQEQATGEWQTQRNQKKKMKKRVKDELRKLNTMTAAEANEIEDVWQLDLSSRWQLYRLWLQLYQADTRRKILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVRLNYQHRMCPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHNFPEQEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFAGVRVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAKVPLWSKIIHTLRENNQIGPMLRLCCQNHPETHTLVSKASDFQKVPEGGCSLPCEFRLGCGHVCTRACHPYDSSHKEFQCMKPCQKVICQEGHRCPLVCFQECQPCQVKVPKTIPRCGHEQMVPCSVPESDFCCQEPCSKSLRCGHRCSHPCGEDCVQLCSEMVTIKLKCGHSQPVKCGHVEGLLYGGLLVKCTTKCGTILDCGHPCPGSCHSCFEGRFHERCQQPCKRLLICSHKCQEPCIGECPPCQRTCQNRCVHSQCKKKCGELCSPCVEPCVWRCQHYQCTKLCSEPCNRPPCYVPCTKLLVCGHPCIGLCGEPCPKKCRICHMDEVTQIFFGFEDEPDARFVQLEDCSHIFEVQALDRYMNEQKDDEVAIRLKVCPICQVPIRKNLRYGTSIKQRLEEIEIIKEKIQGSAGEIATSQERLKALLERKSLLHQLLPEDFLMLKEKLAQKNLSVKDLGLVENYISFYDHLASLWDSLKKMHVLEEKRVRTRLEQVHEWLAKKRLSFTSQELSDLRSEIQRLTYLVNLLTRYKIAEKKVKDSIAVEVYSVQNILEKTCKFTQEDEQLVQEKMEALKATLPCSGLGISEEERVQIVSAIGYPRGHWFKCRNGHIYVIGDCGGAMERGTCPDCKEVIGGTNHTLERSNQLASEMDGAQHAAWSDTANNLMNFEEIQGMM", "length": 1918 }, "evidence": [ { "id": "E1BN24", "url": "https://omabrowser.org/oma/group/E1BN24/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" }, { "name": "nuclear RNA-directed RNA polymerase complex", "id": "GO:0031380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031380", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" }, { "name": "negative regulation of viral genome replication", "id": "GO:0045071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045071", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" }, { "name": "activation of innate immune response", "id": "GO:0002218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated heterochromatin formation", "id": "GO:0031048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031048", "evidence": [ { "database": "UniProtKB", "id": "E1BN24", "url": "https://www.uniprot.org/uniprotkb/E1BN24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1693, "end_pos": 1695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1880, "end_pos": 1882, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN24" }, { "id": "PS51981", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51981" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RZ-type", "eco_id": "ECO_0000259", "start_pos": 1827, "end_pos": 1898, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 1693, "end_pos": 1695 }, { "start_pos": 1880, "end_pos": 1882 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BN28-1", "uniprot_ac": "E1BN28", "uniprot_id": "E1BN28_BOVIN", "mass": { "chemical_mass": 52807.0, "monoisotopic_mass": 52807.0 }, "refseq": {}, "gene_names": [ { "name": "LOC614741", "type": 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3273017, "end_pos": 2953442, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066134.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066134.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056407.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056407.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BN28", "url": "https://www.uniprot.org/uniprotkb/E1BN28" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BN28", "url": "https://www.uniprot.org/uniprotkb/E1BN28" } ], "pmid": 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], "gene": [ { "name": "LOC786254", "url": "https://www.uniprot.org/uniprotkb/E1BN29", "locus": {} } ], "crossref": [ { "id": "E1BN29", "url": "https://alphafold.ebi.ac.uk/entry/E1BN29", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047919", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047919", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000051147", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000051147", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"Protein" ] }, { "id": "E1BN29-1", "url": "https://www.uniprot.org/uniprotkb/E1BN29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZN4", "url": "https://www.uniprot.org/uniprotkb/G3MZN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZN4-1", "url": "https://www.uniprot.org/uniprotkb/G3MZN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCYCLFSAERQVCHLKMLSLLLLLLGLGSVFGALVSQKPSRAIRQRGTSVMIECRQVDSQLTAMYWYRQLPGQSLVLMATANQGSKATYESGFTDNKFPISRPVLAFSTLTVSNASSEDSSSYFCSAGDTVLGTDQGSQQEPLSHPPSSQPGSVFGALLSQEPSRAIRQRGTSMTIECQVDSQLTWMYWYRQLPGQSLVLMATANQGSKATYESGFTEDKFPIDRPKLEFSTLTVSNASSEDSSSYFCSAGDTVLGTVQGSQQEPLSFPPRPR", "length": 273, "header": "tr|E1BN29-1|E1BN29_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC786254 PE=4 SV=5 CANONICAL=E1BN29-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NL94-1", "url": "https://www.uniprot.org/uniprotkb/E1BN29/entry#A0ABI0NL94-1", "sequence": { "sequence": "MLTLLLLLLGLGSVFGALLSQEPSRAIRQRGTSMTIECQVDSQLTWMYWYRQLPGQSLVLMATANQGSKATYESGFTEDKFPIDRPKLEFSTLTVSNASSEDSSSYFCSAGDTVLGTVQGSQQEPLSFPPRPRPGLSWHSELDI", "length": 144, "header": "tr|A0ABI0NL94-1|A0ABI0NL94_BOVIN Computationally mapped isoform of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC786254 PE=4 SV=1 CANONICAL=E1BN29-1" }, "locus": { "chromosome": "4", "start_pos": 106063070, "end_pos": 106061464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142631.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142631.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105765.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105765.1" } ] } }, { "isoform_ac": "A0ABI0NLC5-1", "url": "https://www.uniprot.org/uniprotkb/E1BN29/entry#A0ABI0NLC5-1", "sequence": { "sequence": "MCYCLFSAERQVCHLKMLSLLLLLLGLGSVFGALLSQEPSRAIRQRGTSMTIECQVDSQLTWMYWYRQLPGQSLVLMATANQGSKATYESGFTEDKFPIDRPKLEFSTLTVSNASSEDSSSYFCSAGDTVLGTVQGSQQEPLSFPPRPRP", "length": 150, "header": "tr|A0ABI0NLC5-1|A0ABI0NLC5_BOVIN Computationally mapped isoform of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC786254 PE=4 SV=1 CANONICAL=E1BN29-1" }, "locus": { "chromosome": "4", "start_pos": 106062126, "end_pos": 106056469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153441.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153441.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105815.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105815.1" } ] } }, { "isoform_ac": "A0ABI0NUP6-1", "url": "https://www.uniprot.org/uniprotkb/E1BN29/entry#A0ABI0NUP6-1", "sequence": { "sequence": "MLTLLLLLLGLGSVFGALVSQKPSRAIRQRGTSVMIECRQVDSQLTAMYWYRQLPGQSLVLMATANQGSKATYESGFTDNKFPISRPVLAFSTLTVSNASSEDSSSYFCSAGDTVLGTDQGSQQEPLSHPPSSQP", "length": 135, "header": "tr|A0ABI0NUP6-1|A0ABI0NUP6_BOVIN Computationally mapped isoform of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC786254 PE=4 SV=1 CANONICAL=E1BN29-1" }, "locus": { "chromosome": "4", "start_pos": 106059656, "end_pos": 106054033, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147993.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147993.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107649.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107649.1" } ] } }, { "isoform_ac": "E1BN29-1", "url": "https://www.uniprot.org/uniprotkb/E1BN29/entry#E1BN29-1", "sequence": { "sequence": "MCYCLFSAERQVCHLKMLSLLLLLLGLGSVFGALVSQKPSRAIRQRGTSVMIECRQVDSQLTAMYWYRQLPGQSLVLMATANQGSKATYESGFTDNKFPISRPVLAFSTLTVSNASSEDSSSYFCSAGDTVLGTDQGSQQEPLSHPPSSQPGSVFGALLSQEPSRAIRQRGTSMTIECQVDSQLTWMYWYRQLPGQSLVLMATANQGSKATYESGFTEDKFPIDRPKLEFSTLTVSNASSEDSSSYFCSAGDTVLGTVQGSQQEPLSFPPRPR", "length": 273, "header": "tr|E1BN29-1|E1BN29_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC786254 PE=4 SV=5 CANONICAL=E1BN29-1" }, "locus": { "chromosome": "4", "start_pos": 106062123, "end_pos": 106056469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039006.7", "url": "https://www.ensembl.org/id/ENSBTAT00000039006.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038810.7", "url": "https://www.ensembl.org/id/ENSBTAP00000038810.7" } ] } }, { "isoform_ac": "G3MZN4-1", "url": "https://www.uniprot.org/uniprotkb/E1BN29/entry#G3MZN4-1", "sequence": { "sequence": "MLTLLLLLLGLGSVFGALLSQEPSRAIRQRGTSMTIECQVDSQLTWMYWYRQLPGQSLVLMATANQGSKATYESGFTEDKFPIDRPKLEFSTLTVSNASSEDSSSYFCSAGDTVLGTVQGSQQEPLSFPPRPRPACGISVPQPGIEPSTLLWKCGVLTTGSPGKSLCQFISVVDWTENGESTPFPTFTGLTSCYPGLNSNTISPERAFLTFYAHIVPVDPATSYSHLLSLYSISIMPNH", "length": 239, "header": "tr|G3MZN4-1|E1BN29_BOVIN Computationally mapped isoform of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC786254 PE=4 SV=2 CANONICAL=E1BN29-1" }, "locus": { "chromosome": "4", "start_pos": 106067272, "end_pos": 106061464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064277.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064277.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055035.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055035.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BN29", "url": "https://www.uniprot.org/uniprotkb/E1BN29" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "E1BN29", "url": "https://www.uniprot.org/uniprotkb/E1BN29" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "E1BN29", "url": "https://www.uniprot.org/uniprotkb/E1BN29" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN29-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 273, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN29-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN29" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN29" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 144, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 237, "end_pos": 239 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BN37-1", "uniprot_ac": "E1BN37", "uniprot_id": "E1BN37_BOVIN", "mass": { "chemical_mass": 37621.0, "monoisotopic_mass": 37621.0 }, "refseq": { "ac": "XP_003586143", "name": "E3 ubiquitin-protein ligase MARCHF9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586143" }, "gene_names": [ { "name": "MARCHF9", "type": "recommended", "evidence": [ { "id": "E1BN37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN37" } ] }, { "name": "MARCHF9", "type": "synonym", "evidence": [ { "id": "XP_003586143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586143" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "E1BN37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN37/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "E1BN37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN37/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase MARCHF9", "type": "synonym", "evidence": [ { "id": "XP_003586143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586143" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN37", "url": "https://www.uniprot.org/uniprotkb/E1BN37" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MARCHF9", "url": "https://www.uniprot.org/uniprotkb/E1BN37", "locus": { "chromosome": "5", "start_pos": 55705885, "end_pos": 55710118, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016904", "url": "https://www.ensembl.org/id/ENSBTAG00000016904" } ] } } ], "crossref": [ { "id": "E1BN37", "url": "https://alphafold.ebi.ac.uk/entry/E1BN37", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016904", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016904", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16811", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16811", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540871", "url": "https://www.ncbi.nlm.nih.gov/gene/540871", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540871", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540871", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PNMFKYR", "url": "https://omabrowser.org/oma/group/PNMFKYR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN37", "url": "https://www.orthodb.org/?gene=E1BN37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46053", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46053", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46053:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46053:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003586143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586143", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BN37", "url": "https://www.uniprot.org/uniprotkb/E1BN37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN37-1", "url": "https://www.uniprot.org/uniprotkb/E1BN37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKSRLRMFLNELKLLVLTGGGRPRAEPQPRGGGGGGCGWAPFAGCSARDGDGDEEEYYGSEPRARGLAGDKEPRAGPPPPHAPPPPPPGALDALSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCELCYFKYQVLAISTKNPLQWQAISLTVIEKVQIAAIVLGSLFLVASISWLIWSSLSPSAKWQRQDLLFQICYGMYGFMDVVCIGLIVHEGSSVYRIFKRWQAVNQQWKVLNYDKTKDIGGDAGGGTAGKPGPRTSRTGPPTGATSRPPAAQRMRTLLPQRCGYTILHLLGQLRPPDARSSSNSGREVVMRVTTV", "length": 346, "header": "tr|E1BN37-1|E1BN37_BOVIN Isoform 1 of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=MARCHF9 PE=4 SV=1 CANONICAL=E1BN37-1" }, "isoforms": [ { "isoform_ac": "E1BN37-1", "url": "https://www.uniprot.org/uniprotkb/E1BN37/entry#E1BN37-1", "sequence": { "sequence": "MLKSRLRMFLNELKLLVLTGGGRPRAEPQPRGGGGGGCGWAPFAGCSARDGDGDEEEYYGSEPRARGLAGDKEPRAGPPPPHAPPPPPPGALDALSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCELCYFKYQVLAISTKNPLQWQAISLTVIEKVQIAAIVLGSLFLVASISWLIWSSLSPSAKWQRQDLLFQICYGMYGFMDVVCIGLIVHEGSSVYRIFKRWQAVNQQWKVLNYDKTKDIGGDAGGGTAGKPGPRTSRTGPPTGATSRPPAAQRMRTLLPQRCGYTILHLLGQLRPPDARSSSNSGREVVMRVTTV", "length": 346, "header": "tr|E1BN37-1|E1BN37_BOVIN Isoform 1 of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=MARCHF9 PE=4 SV=1 CANONICAL=E1BN37-1" }, "locus": { "chromosome": "5", "start_pos": 55709919, "end_pos": 55706889, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022483.5", "url": "https://www.ensembl.org/id/ENSBTAT00000022483.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022483.3", "url": "https://www.ensembl.org/id/ENSBTAP00000022483.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:540871", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540871", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F4X3-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "marchf9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFKNRIRMFFNELKVLVFMRSGSRRSDSDAESNRRSGSNMRGLGMGGCGWPPFVDCSSRDDEEEYYGSDPRPRSLAFEEKDPKLQAGLDAVSLTSSTGSGMRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCELCYFKYQVLAISTKNPLQWQAISLTVIEKVQIAAIILGSLFLIASISWLVWSSLSPSAKWQRQDLLFQICYGMYGFMDIVCIGLIIHEGSSVYRIFKRWQAVNQQWKVLNYEKSKDLGDPLSSSSKAGGRGSRSNPHGLASGSRGAQRVRRLRTILNHHCGYTILHILSQLRPSDPRLGTATNREVVMRVTTV", "length": 342 }, "evidence": [ { "id": "E1BN37", "url": "https://omabrowser.org/oma/group/E1BN37/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0RDZ7-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Marchf9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKSRLRMFLNELKLLVLTGGGRPRAEPQPRGGGGGGCGWAPFAGCSARDGDGDEEEYYGSEPRARGLAGDKEPRAGPPPPPAPPPPPPGALDALSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCELCYFKYQVLAISTKNPLQWQAISLTVIEKVQIAAIVLGSLFLVASISWLIWSSLSPSAKWQRQDLLFQICYGMYGFMDVVCIGLIVHEGSSVYRIFKRWQAVNQQWKVLNYDKTKDVGGDAGGGAAGKPGPRTSRTSPPAGAPSRPPAAQRMRTLLPQRCGYTILHLLGQLRPPDARSSSHSGREVVMRVTTV", "length": 346 }, "evidence": [ { "id": "E1BN37", "url": "https://omabrowser.org/oma/group/E1BN37/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TZ87-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF9", "gene_name": "Marchf9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKSRLRMFLNELKLLVLTGGGRPRAEPQPRGGGGGGCGWAPFAGCSARDGDGDEEEYYGSEPRARGLAGDKEPRAGPPPPPAPPPPPPGALDALSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCELCYFKYQVLAISTKNPLQWQAISLTVIEKVQIAAIVLGSLFLVASISWLIWSSLSPSAKWQRQDLLFQICYGMYGFMDVVCIGLIVHEGSSVYRIFKRWQAVNQQWKVLNYDKTKDVGGDTGGGAAGKPGPRTSRTSPPAGAPTRPPAAQRMRMRTLLPQRCGYTILHLLGQLRPPDARSSSHSGREVVMRVTTV", "length": 348 }, "evidence": [ { "id": "E1BN37", "url": "https://omabrowser.org/oma/group/E1BN37/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86YJ5-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF9", "gene_name": "MARCHF9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BN52-1", "uniprot_ac": "E1BN52", "uniprot_id": "E1BN52_BOVIN", "mass": { "chemical_mass": 244920.0, "monoisotopic_mass": 244920.0 }, "refseq": { "ac": "NP_001179924", "name": "FRAS1-related extracellular matrix protein 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179924" }, "gene_names": [ { "name": "FREM1", "type": "recommended", "evidence": [ { "id": "E1BN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN52" } ] }, { "name": "FREM1", "type": "synonym", "evidence": [ { "id": "NP_001179924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179924" } ] } ], "protein_names": [ { "name": "FRAS1-related extracellular matrix protein 1", "type": "recommended", "evidence": [ { "id": "E1BN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN52/entry#names_and_taxonomy" } ] }, { "name": "FRAS1-related extracellular matrix protein 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001179924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179924" } ] }, { "name": "Protein QBRICK", "type": "synonym", "evidence": [ { "id": "E1BN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN52/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52#function" }, { "database": "UniProtKB", "id": "ARBA00058451", "url": "https://www.uniprot.org/uniprotkb/ARBA00058451#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FREM1", "url": "https://www.uniprot.org/uniprotkb/E1BN52", "locus": { "chromosome": "8", "start_pos": 29453914, "end_pos": 29303140, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020141", "url": "https://www.ensembl.org/id/ENSBTAG00000020141" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020141", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020141", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "508018", "url": "https://www.ncbi.nlm.nih.gov/gene/508018", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:508018", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508018", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DIGPHLQ", "url": "https://omabrowser.org/oma/group/DIGPHLQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN52", "url": "https://www.orthodb.org/?gene=E1BN52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45739", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45739", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45739:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45739:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19309", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19309", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179924", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN52-1", "url": "https://www.uniprot.org/uniprotkb/E1BN52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPSWGGLGALLLLLLLPGWASPTFVRVNQGVRVMKGSSAFLSQDDLKFTIPKEKDACKVEVVMNEPITQRVGKLTPQVFDCHFLPNEVKYTHNGCPILDEDTVKLRLYRFTETDTFTETFILRVYLLEPDCNIIRMSDNALEVSEFYGLSRVIDKNLLRFDYERMASLECTVRLDPVGTHLPAHGQLVLVEPQLEEPRGDQPHSFFPESQLGTELKCPGGRCTLGLKKVGSLKVSCEEFLLMGLRYQHLGSPSPNIDYFSIQLDLTDSRSKISYKSESAWLPVYIRPGIPNQIPRAAFMAMFILEVDQFILTSLTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLWDHTRPVSSFTWKDLRDMQIAYQPPNSSHSERRLYEVELEVYDFFFEKSAPITVHISIRTTDTNAPRVSWNTGLNLLEGQSRAITWEQFQIVDNDDIHAVQVVTVDGLQHGRLTVRGGKGFLFTVADLQAGVVRYHHDDSDSTKDFVVFRIFDSQHSIQHKFPINILPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDMDSSDDYIFFNITKPPQAGEIMKKPAPGLIGYPVPGFIQRDLFNGIIYYRHFGGEIFEDSFEFVLWDSHEPPNLSVPQVVTIHVTPVNDQLPKEAPGVSRHLVVKETEVAYITKKHLHFIDTESQDRELLYTITTPPFFSSSRRHLDAGKLFMVDSIPRLTKTPAAPGLKYFTQHAVNHMKVAYMPPMQDVGPHPRHVQFAFSVSNQHGGTLYGICFNITILPVDNQAPKVFTKPLRVAEGGQCVISTQHVLVSDEDTKLDNIYLSLQSPPQHGMVELNGFPLNKGTTFPWGVLQALKLRYQHDGSEELQDDIVLQVTDGTNTAEYVLHVEVFPVNDEPPVLKADLIPMMHCSEGEEVVITSEYIFATDVDSDDLKLIFMIVGEPQHGTVRRAGVTVHQFSQEDVVAGAVTYKHTGGEIGLMPCFDTITLVVSDREAGPFVNGCCYNGPHPSVPLHESFPMYDLNITVYPVDNQPPSVAIGTTFVVDEGFSAALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENTLPSAGFEKSNMGISIASFQWKDMKALHINYVQSRHLGMEPTADKFVLYVTDGKRRSMEIPFYIIINATNDEAPDFIVQNITVCEGQMRELDSSIISATDRDIPKNPLLFSITHKPRHGLLINRAFSRNFFQYKQLANPGQKHELVYNFSMELLKNGMRLVYVHDDSESLADDFTIQVSDGKHKILKTIFVEVTPVNDEKPMLSKKAEITINMGETRIISSAVLSAIDEDSPREKIYYIFERIPQNGQLQLKIGRDWVPLYPGMKCTQEEVDLNLLRYTHTGAMDSKNQDSFTFRLWDGDNRSPAFDCHITIKNMGKGDIVILAKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPQFGQVEYVRYPGVPITSFSQMDIAGQTVCYVDKSTTAVHRDTFRFIVSNGLQTKPGVFEITLETVDTALPVVTRNKGLRLVEGATGLLSPDLLQLTDPDTPAEKLTFLLAQLPRHGQLYLRGMALIPHNFTQLDVDSGHVAYRHLGGDSWTDHFTFVATDGTNHGFLVDGRVWQEPVSFTIQVDQLDKAAPRVTHLHSPSQVGLLKNGCYGIYITSRVLKASDPDTDDNQIIFKILRGPQHGHLENSTTGEFIHEKFSQKDLNSKTVLYIINPSLEVNSDTMEFQVMDPTGNSATPQSLELNWSYIEWSRTEYEVCENMGMLPLEITRRGYSMDSAFVTVQVNQVSATVGKDFTMTPSKLVQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKTAVKILDSKGGQCHPSNAFNSNMPSAWEKGIWHLLSPGASSPTTSDSFHLERRPLPTSKQLAVTRGDALRDFGSEDLSPVKLRTRGDGKTVPPSSVYKNRTDIIYNYHGVISLKLEDDGSPARRRKANVSFISEPQKTTKVAEPPQADKEESTTGSHFPRQDPLPSFPKNCTPELKGLFHFEESLQKLYKCDGIAWRSWSPHTKEVEDKSCPAGWHHHSGYCHSLITEQKGTWTTAAQACREHYQGSLVTVISRQHMRWLWDISGRKPFWIGLNDQVRAGHWEWIGGEPVTFTNWRRGPPQRSRHGKDCVLVQRPGKWHTKDCRKGKSHSYVCSRKL", "length": 2180, "header": "tr|E1BN52-1|E1BN52_BOVIN Isoform 1 of FRAS1-related extracellular matrix protein 1 OS=Bos taurus OX=9913 GN=FREM1 PE=3 SV=2 CANONICAL=E1BN52-1" }, "isoforms": [ { "isoform_ac": "E1BN52-1", "url": "https://www.uniprot.org/uniprotkb/E1BN52/entry#E1BN52-1", "sequence": { "sequence": "MSSPSWGGLGALLLLLLLPGWASPTFVRVNQGVRVMKGSSAFLSQDDLKFTIPKEKDACKVEVVMNEPITQRVGKLTPQVFDCHFLPNEVKYTHNGCPILDEDTVKLRLYRFTETDTFTETFILRVYLLEPDCNIIRMSDNALEVSEFYGLSRVIDKNLLRFDYERMASLECTVRLDPVGTHLPAHGQLVLVEPQLEEPRGDQPHSFFPESQLGTELKCPGGRCTLGLKKVGSLKVSCEEFLLMGLRYQHLGSPSPNIDYFSIQLDLTDSRSKISYKSESAWLPVYIRPGIPNQIPRAAFMAMFILEVDQFILTSLTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLWDHTRPVSSFTWKDLRDMQIAYQPPNSSHSERRLYEVELEVYDFFFEKSAPITVHISIRTTDTNAPRVSWNTGLNLLEGQSRAITWEQFQIVDNDDIHAVQVVTVDGLQHGRLTVRGGKGFLFTVADLQAGVVRYHHDDSDSTKDFVVFRIFDSQHSIQHKFPINILPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDMDSSDDYIFFNITKPPQAGEIMKKPAPGLIGYPVPGFIQRDLFNGIIYYRHFGGEIFEDSFEFVLWDSHEPPNLSVPQVVTIHVTPVNDQLPKEAPGVSRHLVVKETEVAYITKKHLHFIDTESQDRELLYTITTPPFFSSSRRHLDAGKLFMVDSIPRLTKTPAAPGLKYFTQHAVNHMKVAYMPPMQDVGPHPRHVQFAFSVSNQHGGTLYGICFNITILPVDNQAPKVFTKPLRVAEGGQCVISTQHVLVSDEDTKLDNIYLSLQSPPQHGMVELNGFPLNKGTTFPWGVLQALKLRYQHDGSEELQDDIVLQVTDGTNTAEYVLHVEVFPVNDEPPVLKADLIPMMHCSEGEEVVITSEYIFATDVDSDDLKLIFMIVGEPQHGTVRRAGVTVHQFSQEDVVAGAVTYKHTGGEIGLMPCFDTITLVVSDREAGPFVNGCCYNGPHPSVPLHESFPMYDLNITVYPVDNQPPSVAIGTTFVVDEGFSAALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENTLPSAGFEKSNMGISIASFQWKDMKALHINYVQSRHLGMEPTADKFVLYVTDGKRRSMEIPFYIIINATNDEAPDFIVQNITVCEGQMRELDSSIISATDRDIPKNPLLFSITHKPRHGLLINRAFSRNFFQYKQLANPGQKHELVYNFSMELLKNGMRLVYVHDDSESLADDFTIQVSDGKHKILKTIFVEVTPVNDEKPMLSKKAEITINMGETRIISSAVLSAIDEDSPREKIYYIFERIPQNGQLQLKIGRDWVPLYPGMKCTQEEVDLNLLRYTHTGAMDSKNQDSFTFRLWDGDNRSPAFDCHITIKNMGKGDIVILAKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPQFGQVEYVRYPGVPITSFSQMDIAGQTVCYVDKSTTAVHRDTFRFIVSNGLQTKPGVFEITLETVDTALPVVTRNKGLRLVEGATGLLSPDLLQLTDPDTPAEKLTFLLAQLPRHGQLYLRGMALIPHNFTQLDVDSGHVAYRHLGGDSWTDHFTFVATDGTNHGFLVDGRVWQEPVSFTIQVDQLDKAAPRVTHLHSPSQVGLLKNGCYGIYITSRVLKASDPDTDDNQIIFKILRGPQHGHLENSTTGEFIHEKFSQKDLNSKTVLYIINPSLEVNSDTMEFQVMDPTGNSATPQSLELNWSYIEWSRTEYEVCENMGMLPLEITRRGYSMDSAFVTVQVNQVSATVGKDFTMTPSKLVQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKTAVKILDSKGGQCHPSNAFNSNMPSAWEKGIWHLLSPGASSPTTSDSFHLERRPLPTSKQLAVTRGDALRDFGSEDLSPVKLRTRGDGKTVPPSSVYKNRTDIIYNYHGVISLKLEDDGSPARRRKANVSFISEPQKTTKVAEPPQADKEESTTGSHFPRQDPLPSFPKNCTPELKGLFHFEESLQKLYKCDGIAWRSWSPHTKEVEDKSCPAGWHHHSGYCHSLITEQKGTWTTAAQACREHYQGSLVTVISRQHMRWLWDISGRKPFWIGLNDQVRAGHWEWIGGEPVTFTNWRRGPPQRSRHGKDCVLVQRPGKWHTKDCRKGKSHSYVCSRKL", "length": 2180, "header": "tr|E1BN52-1|E1BN52_BOVIN Isoform 1 of FRAS1-related extracellular matrix protein 1 OS=Bos taurus OX=9913 GN=FREM1 PE=3 SV=2 CANONICAL=E1BN52-1" }, "locus": { "chromosome": "8", "start_pos": 29452910, "end_pos": 29303339, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026827.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026827.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026827.4", "url": "https://www.ensembl.org/id/ENSBTAP00000026827.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1907, "start_aa": "Thr", "end_pos": 1907, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1907", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:508018", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508018", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KB00-1", "protein_name": "FRAS1-related extracellular matrix protein 1", "gene_name": "Frem1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHSPGCTGPKALLFLLLQLLMLHLDPANATFISINRGLRVMKGSSAFLSGDHLRFAIPKEKDACRVEVVMNEPITQRVGKLIPQVFDCHFLPNEVQYVHNGCPILDEDSVKLRLYRFTETETFMETFLLRVSLVEPDCNIIRLSSNVLEVTEFYGLSQAIDKNLLQFDYDRTASLDCTIRVDPVKTQLPAHGKLVVVNRKSEGPRGDQPHSFFSESQLGAERKCPDGSCTLEPKQVTSLKVSCEDFLLTGFHYQHMQPPSPNIDYIPIQLDLTDRRSKTIYKSESAWLPVFIRVGIPNQAPRAAFMAMFVLEVDQFILTPLTTSVLDCEEDETPKPLLVFNITEAPLQGYVTHLLDHTRPISSFTWKDLSDMQVAYQPPNNSHPERRHYKMELEVYDLFFERSAPITVHISIRTADTNAPRVSWNTGLNLLEGQSRAITWEQFQIVDNDDIGAVQLVTIGGLQHGRLTVREGKGFLFTVADLQAGVVRYHHDDSDTTKDFVAFRIFDGQHSSHHKFPINILPKDDSPPFLITNVVIELEEGKTILIQGSMLRASDMDSSDDYIFFNITKFPQAGEIMKKPGPRLIGYPVSGFLQRDLFSGIIYYRHFGGEIFEDSFEFVLWDSHEPPNLSVPQVVMVHITPVDDQLPKEAPGISRHLIVKETEVAYITKKHLHFLDTESHGGELVYTITRPPCFSSSHRHLDAGKLFMVDSIPKPTKNPTAPGLNSFTQHAVNHMKVAYMPPMQDIGPTPRHVQFTVSVSNQHGGTLHGICFNITVLPVDNQVPEVFTNTLRVAEGGQCTISTEHILVSDVDTPLDSICLSLQEMPLHGGVELDGFPLNPRGTFSWRDLHTLKVRYQHDGSEVLQDEIFLEVTDGTNSAGFVLYIEVFPVNDEPPVLKADLIPMMHCSEGGEVTITPEYIFATDADSNDSELLFLITREPRHGVVRKAGLRVDRFSQGDVISGAVAYKHTGGEIGLESCFDTVVLVVSDGEADPLVNGCCYNGPDSSVPLHKSFPTYQLNITVHPVDNQPPSIIIGRTLTVDEGFSAALTTHHLTATDWDTAPDDLEFILVSHPQFGYLENTLPSAGFEKRNTGISIASFQWRDMKASHINYVQSRHLREEPTADEFLVYATDGKQRSLETTFHVIINPTNDEAPDFVVQNITVYEGHMVELDSAIISATDRDVPKDPLLFNITHKPKHGLLLISATSKDAHNEIHNFSMELLQNGMKLAYAHDDSESSADNFVIQLSDGKHKILKTVSVSITPVNDETPTLSKKAEVSVTVGDTRVLSSAVLSAIDKDSPREKIHYLFERLPQNGQLQLKIGRDWVPLSAGMQCTQEDVDLNLLRYAHAGKMHSQDGDRFTFYLWDGDNRSPAFDCHIIIEDTGRGDIVIHAKPLVVANGDRGLLTPATLLAEDGADKAEELLYLITSPPQYGQVEYVYSPGVPITSFSQMDIAGQAVCYIHKSRTAVLSDSFRFTISNGLQTQQGVFEITLQGVDSALPVLTRNRRLRLVEGAMGLLSTDHLQLTDPDTPPENLTFFLVQLPRHGYLYLRGKVLQHNFTQQDVDSRVVAYQHAGGGAQEDCFTFLATDRKNQGFVVDGKVQKEPVLFIIQVDQLDKKAPRITRLHSPSQVGLLKNGCYGIYITSHVLKASDPDTEDDQIIFKILRGPLHGRLENTTTGEFIHEQFSQKDLSRKTILYIINPSLQVNSDILEFQAMDPTGNTAPPQRLELKWSYIEWSQTEYEVCENVGLLTLEVTRRGYSMDSAYVDIEVNQVSAVVGKDFTVTPSKLLQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTQTKAAVKILDSKGGRCHPSNSFNQSKHSTWGKGRWHPLPSGSSSLTTSGSPHLERRPPPSITKGDALRGFDLTDLSQRKMTTQGNGKSVLPSSVCRNGTDTIYNYHGIVSLKLEGDRFSAHKRKAKISVIRQPQRTVKVAELPLADKVEPTTDSNFLSQGLRPLFPKNCSVELKGLFHLEEHTHRLYQCDGIAWNVWSSQTKGLEDRSCPVGWLLHSDYCHVLVTRQKGTWATATRACREQHQGTLVTVFSRRHMQWLWAISGRKPFWIGLKNQVRTGHWEWIGGEPVAFTNWRRGPPLHPKPGKNCVLVQRRGQWQTKNCSKGKAHNFVCSRKL", "length": 2167 }, "evidence": [ { "id": "E1BN52", "url": "https://omabrowser.org/oma/group/E1BN52/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YPJ1-1", "protein_name": "FRAS1-related extracellular matrix protein 1", "gene_name": "FREM1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKPFEKTWLLLLLPVLLRVVCSSFVSVNLGIKVMKGQSVFLSEDDLKFSIPREKDVCKVEVVRNEPITQRVGKLTPQVFDCHFHLNEVKYTHNGCPILDADTVMLRLYRFTENETFVETFTLHVQLLEPDCNIIKMRSRALEVAEYYGLSRAIDKNSLTFDYSRKMNLECTISIASSETHLPAHGQLIMGDTRQEKLRGDQPQSFLLGPKHSPGQQCRNGSCVLGLRVIHNTKMSCEEFLRKGIRYQHLDPRSPDIDYIPVRLDLTDSRSKTLHKTEYAWLPVRIKSAMPNQIPKAVPMTKFILEVDQFILTPITTTTVDAEDKETPKSLLVFNITKPPLQGFITHLSDHTKPVGSFTWKDLSEMLIAYQPPNNSHTERRNYELEVEVHDFYFERSLPTIVQLSIRTADTNAPRVSWNTGLSLLEGQSRPITWQHLQVVDNDDIQNVRLVTVDGLQHGRLTVRGGKGFMFTVSDIQTGVVRYHHDDSDSTKDFVVFRIFDGLHSIRHKFPINILPKDDSPPFLISNVVIEVQEGQTILIQGSMLQASDMDSSDDYIVFNITKPPQAGEIMKKPGPNLIGYPVSSFLQRDLFNGIMYYHHLGGEVFEDSIEFVLCDSHDPPNLSEPQVMTVHIAPVDDQLPKEAPGVTRHLVVKETEIAHLTKKHLHFIDVEEQDRELTYTITTSPFFSCVHGHSDAGKLFMVDTIPKLVKDPAALALRSFTQHAVNYLKVAYMPPLQDIGPNPQHVQFVFSVSNQHGGTLYGICFNITILPVDNQAPEVLTSHLRVEEGGLSPVTEGHILVSDVDTKQEHLLLLLQRQPQHGAVELDGVPMKEGDKLSCADLRTLAVSYRHDGSETLTDEVLFVATDGIHSLEFTLQVKVLPMNDEPPVVQTGLINVLSCPEGEEVVLSSEYIYATDADSDDMKLVFVLVRQPSQGVLRRAGIAVERFSQADVISGLVTYKHTGGEIGLTLTFETLTFVVSDDEAGPDVKDCCYDRLLPPPVPPHRPLPVYDLNITVLPVDNQPPSIAIGARFVVEEGSSAALTSNHLFATDPDTPADDLEFVLVSPPQFGYIENILPSPGFEKSNVGISIASFQLKHLKALNINYVQARHMRMEPRADHFVLYVTDGLHRSAEIPFFVLINPTNDEVPEFIARNITVQEGMMKELDLSVISAVDLDVPQDHLVFGVVQQPSHGFLINGVHGNDILHYKELIQHHNHGLLVHDFSMELLQNGMKLMYMHDDSESLSDSFKIQLSDGKHKVLRTISVKVIPVNDEKPVLSKKDNIEVHMGETRIISSAVLSAEDKDTPRERIYYLFERLPESGQLQLKVGRDWVTLQTGMKCTQEELDMNLVRYVHTGAIGSKNQDLFTFYLWDGYNRSPAVDFYINIKDMEKGDIAVFIKPLKVSKGDRGYITTDVLLSLDGTDKPEELLYVITSPPQYGQIEYASYPDIPITSFSQMDVASQIVCYVHNTKAHSRQDAFRFIISNGLRTKHGTFMISLEAVDQTLPTLSRNRGLRLVEGNMVLLSPDVLQLTDSDTAKENLTFILAQLPQYGHLYYRGAVLLQYSFTQRDVDNMDVAYKHRGGDSRVDKFTFVATDRTNQGFIVNGRVQIEPVAFTIQVDHLDKMAPKIIHLRCLSDVEMLKNGNYGIYITSRSLKATDPNTEDDKIFFKILQGPRYGYLENITTGGLIHEGFSQKDLNSKIIFYVINPLWEVHSDNLEFQVTDTNGNSAIPQMLELRWSRIEMQQTEYEVCENVGTVSLKITRAGHSADSAFIAVKVNEISAVLGKDFTVTPSKLIQFDPGMSTKMWNIAITYDRLEEDDEVFEVVLNSSVNAVLGTKTKAVVKILDSKGGQCSTLHSSSQSKQDFWRRGTLFAVSSGSSSPPRPGNVHLEGISPPPSKRMREHRGDTLQDRRLAYQSRAKLRVTGNGRIVHPSSIFRNGTDVVYKYHGIVSLKIEDDTSSAKANKKAEVSVINQAQPQINAISTRKTEIPQADKAELASEASSRRQDFHSFSRACTPDLKGLMHYEESTQKLFQCDGIEWKFWSSQSKEASMKKCPSGWRHHDGSCYFLVVNQKVTWDTAAQACREQYLGSLTSVANEQHMQWLWDLGGRKPFWIGLNDQVNPGHWEWNGGEPVTYINWRRGSYRFTKRGNNCVVVQKRGKWQATDCRKAKWNSYICSRKL", "length": 2184 }, "evidence": [ { "id": "E1BN52", "url": "https://omabrowser.org/oma/group/E1BN52/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5H8C1-1", "protein_name": "FRAS1-related extracellular matrix protein 1", "gene_name": "FREM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSLSWGAANAVLLLLLLAWASPTFISINRGVRVMKGHSAFLSGDDLKFAIPKEKDACKVEVVMNEPITQRVGKLTPQVFDCHFLPNEVKYVHNGCPILDEDTVKLRLYRFTERDTFIETFILWVYLLEPDCNIIHMSNNVLEVPEFNGLSQAIDKNLLRFDYDRMASLECTVSLDTARTRLPAHGQMVLGEPRPEEPRGDQPHSFFPESQLRAKLKCPGGSCTPGLKKIGSLKVSCEEFLLMGLRYQHLDPPSPNIDYISIQLDLTDTRSKIVYKSESAWLPVYIRAGIPNQIPKAAFMAVFILEVDQFILTSLTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTWKDLSDMQIAYQPPNSSHSERRHDEVELEVYDFFFERSAPMTVHISIRTADTNAPRVSWNTGLSLLEGQSRAITWEQFQVVDNDDIGAVRLVTVGGLQHGWLTLRGGKGFLFTVADLQAGVVRYHHDDSDSTKDFVVFRIFDGHHSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDASDDYIFFNITKPPQAGEIMKKPGPGLIGYPVHGFLQRDLFNGIIYYRHFGGEIFEDSFQFVLWDSHEPPNLSVPQVATIHITPVDDQLPKEAPGVSRHLVVKETEVAYITKKQLHFIDSESYDRELVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHCRDVQFTFSVSNQHGGTLHGICFNITILPVDNQVPEAFTNPLKVTEGGQSIISTEHILISDADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSWGDLHTLKVRYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMNCSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVDQLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSSTTSGSFHLERRPLPSSMQLAVIRGDTLRGFDSTDLSQRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKTIKVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQTKDVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQTKDCRRAKPHNYVCSRKL", "length": 2179 }, "evidence": [ { "id": "E1BN52", "url": "https://omabrowser.org/oma/group/E1BN52/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q684R7-1", "protein_name": "FRAS1-related extracellular matrix protein 1", "gene_name": "Frem1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHSPGCTGPKAQWFLLLQLLLLHLDRVSATFISINRGLRVMKGSSAFLSGDHLRVAVPKEKDACRLEVVMNEPVTQRVGKLSPQVFDCHFLPNEVKYVHNGCPILDEDSVKLRLYRFTETDTFMETFLLRVYLVEPDCNIIRMSSNVLEVTEFYGLSQAIDKNLLQFDYDRTASLDCTIRLDPLRTQLPAHGKLVVVNRKSEGPRGDQPHSFFSETELGAGLKCPDGSCALELKQVASLKVSCEEFLLTGFHYQHMQPPSPNIDYIPIQLDLTDRRSKTVYKSESAWLPVYIRVGIPNQVPRAAFMAMFVLEVDQFILTPLTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTWKDLSDMQVAYQPPNSSHPERRHYTMELEVYDFFFERSAPITVHISIRTADTNAPRVSWNTGLNLLEGQSRAITWEQFQIVDNDDIGAVQLVTIGGLQHGRLTVREGKGFLFTVTDLQAGVVRYHHDDSDTTKDFVAFRIFDGHHSSHHKFPINILPKDDSPPFLITNVVIELEEGKTILIQGSMLRASDMDSSDDYIFFNITKFPQAGEIMKKPGPRLIGYPVPGFLQRDLFSGIIYYRHFGGEIFEDSFEFVLWDSHEPPNLSVPQVVTIHITPVDDQLPKEAPGISRHLVVKETEVAYITKKHLHFLDMESRDGELIYTVTRPPCFSFSHRHLDAGKLFMVDSIPKLTKNPTAPGLSSFTQGLILISANQHTCSSQFASQHAVNHMKVAYMPPMQDIGPSPRHVQFTVSVSNQHGGALHGICFNITVLPVDNQVPEVFTNTLRVVEGGQCTISTEHILVSDVDTPLDSISLSLKERPLHGGVELDGFPLNPRGTFSWRDLNTLKVWYQHDGSEVLQDEIFLEVTDGTNSAAFVLHIEVFPVNDEPPILKADLIPMMHCSEGGEVTITPEYISATDADSDDLELLFLIAREPQHGVVRKAGLHVDRFSQGDVISGAVTYKHTGGEIGLEPCSDTVVLVVSDGEADPLMNGCCYDGPDSSVPLHKSFPTYQLNITVHPVDNQPPSIIIGRMLTVDEGFSAALTTHHLTVVDWDTAPDDLKFMLASQPQFGYLENALPSAGFEKSNIGIRIASFQWTDMKASHINYVQSRHLRVEPTADQFTVYATDGKHRSLETTFHVIINPTNDEAPDLAVQNITVYEGHMVELDSSIISATDRDIPKDPLLFSIALKPQHGLLVDAAISKDSHQIKQLQHEIHSFSVDLLKNGMKLVYAHDDSESSADNFVIQLSDGKHKILKTISVNITPVNDETPTLSKKAEISMAVGDTRVLSSAVLSATDKDSPREKIHYVFERLPQNGQLQLKIGRDWVPLSTGMQCTQEDVDLNLLRYTHAGKTDSQDGDSFTFYLWDEDNRSPAFDCHIIIEDMGKGDIVIHAKPLVVVKGDRGLLTTATLLAVDGADKPEELLYLITSPPRHGQVEYVHSPGVPIASFSQMDIAGQTVCYIHKSRTAVPTDSFRFTISNGLQTQRGVFEITLQTVDSALPVLTKNKRLRLAEGAMGLLSADHLQLTDPDTPPENLTFFLAQLPRHGYLFLRGKALQHNFTQRDVDSGGVAYQHSGGGAREDYFTFLATDRKNQGFVVDGKVQKEPVRFTIQVDQLDKAAPRITHLHSPTQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILRGPLYGRLENTTTGEFIHERFSQKDLSHKTILYIINPSLQVTSDILEFQAMDPTGNTATPQSLDLRWSYIEWAQTAYEVCENVGLLPLEVTRRGYPMDSAFVGVEVNQVSATVGKDFTVTPSKLLQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTQTKAAVKILDSKGGRCHPSNSFNQSKHSTWGKGPWHPLPSGSSSLTTSGSPLLERPPPSFTSGDALQGFGLTDLTQRKTMTQGNGKSVLPSSVCRNGTDTIYNYHGIVSLKLEGDRFSAHKRKAKISIVSQPQRTIKVAELPLADKVESTTDLHFLRQGLRPLFPKNCSVDLKGLFHFEESTHRLYQCDGISWKAWSPQTKGLEDRSCPGGWLLHSGYCHILVTRQKGTWTTATRACREQHQGDLVTVLSRRHMQWLWAMSGRKPFWIGLKNQPRTGHWEWIGGEPVAFTNWRRGAPLHPKPGKNCALVQKRGQWQTKNCSKGKAHNFVCSRKL", "length": 2191 }, "evidence": [ { "id": "E1BN52", "url": "https://omabrowser.org/oma/group/E1BN52/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "craniofacial suture morphogenesis", "id": "GO:0097094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097094", "evidence": [ { "database": "UniProtKB", "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52" } ], "pmid": "" }, { "name": "cell communication", "id": "GO:0007154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007154", "evidence": [ { "database": "UniProtKB", "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52" } ], "pmid": "" }, { "name": "epithelial structure maintenance", "id": "GO:0010669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010669", "evidence": [ { "database": "UniProtKB", "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "E1BN52", "url": "https://www.uniprot.org/uniprotkb/E1BN52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, "end_pos": 1017, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1143, "end_pos": 1145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1156, "end_pos": 1158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1224, "end_pos": 1226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1377, "end_pos": 1379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1567, "end_pos": 1569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1684, "end_pos": 1686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1740, "end_pos": 1742, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1942, "end_pos": 1944, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1971, "end_pos": 1973, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2013, "end_pos": 2015, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN52" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 2061, "end_pos": 2168, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1907 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1015, "end_pos": 1017 }, { "start_pos": 1143, "end_pos": 1145 }, { "start_pos": 1156, "end_pos": 1158 }, { "start_pos": 1224, "end_pos": 1226 }, { "start_pos": 1377, "end_pos": 1379 }, { "start_pos": 1567, "end_pos": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BN70-1", "uniprot_ac": "E1BN70", "uniprot_id": "E1BN70_BOVIN", "mass": { "chemical_mass": 117887.0, "monoisotopic_mass": 117887.0 }, "refseq": { "ac": "NP_001180016", "name": "integrator complex subunit 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180016" }, "gene_names": [ { "name": "INTS3", "type": "recommended", "evidence": [ { "id": "E1BN70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ] }, { "name": "INTS3", "type": "synonym", "evidence": [ { "id": "NP_001180016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180016" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 3", "type": "synonym", "evidence": [ { "id": "E1BN70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN70/entry#names_and_taxonomy" } ] }, { "name": "integrator complex subunit 3", "type": "synonym", "evidence": [ { "id": "NP_001180016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180016" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "INTS3", "url": "https://www.uniprot.org/uniprotkb/E1BN70", "locus": { "chromosome": "3", "start_pos": 16625276, "end_pos": 16664559, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006235", "url": "https://www.ensembl.org/id/ENSBTAG00000006235" } ] } } ], "crossref": [ { "id": "E1BN70", "url": "https://alphafold.ebi.ac.uk/entry/E1BN70", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006235", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006235", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "511052", "url": "https://www.ncbi.nlm.nih.gov/gene/511052", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511052", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511052", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FEQYCLW", "url": "https://omabrowser.org/oma/group/FEQYCLW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN70", "url": "https://www.orthodb.org/?gene=E1BN70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13587:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13587:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001180016", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180016", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN70-1", "url": "https://www.uniprot.org/uniprotkb/E1BN70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELQKGKGAAAAAASGAAGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTTGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILMEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQALRQKEVDFCISLLRERFMECLMVGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHMSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDITPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKGHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSLLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNATQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1040, "header": "tr|E1BN70-1|E1BN70_BOVIN Isoform 1 of Integrator complex subunit 3 OS=Bos taurus OX=9913 GN=INTS3 PE=3 SV=1 CANONICAL=E1BN70-1" }, "isoforms": [ { "isoform_ac": "E1BN70-1", "url": "https://www.uniprot.org/uniprotkb/E1BN70/entry#E1BN70-1", "sequence": { "sequence": "MELQKGKGAAAAAASGAAGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTTGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILMEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQALRQKEVDFCISLLRERFMECLMVGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHMSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDITPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKGHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSLLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNATQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1040, "header": "tr|E1BN70-1|E1BN70_BOVIN Isoform 1 of Integrator complex subunit 3 OS=Bos taurus OX=9913 GN=INTS3 PE=3 SV=1 CANONICAL=E1BN70-1" }, "locus": { "chromosome": "3", "start_pos": 16664005, "end_pos": 16626307, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008186.6", "url": "https://www.ensembl.org/id/ENSBTAT00000008186.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008186.5", "url": "https://www.ensembl.org/id/ENSBTAP00000008186.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511052", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511052", "resource": "KEGG Pathway" }, { "id": "R-BTA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AI04-1", "protein_name": "Integrator complex subunit 3", "gene_name": "INTS3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEMQKGKGGAAGGGGGKLLLSTLLDAKDELEERLERCVGIVTSLTNGLSEREANDALNAHICKGTPQHEEICLGLFTLVLTEPTQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLMWLLRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAENVLEILTEQREWVLKSSLLIAMAVYTYLRLIVDHHGTAPLQALRQKEVDFCISLLRERFMDCFMIGRDLVRLLQNVARIPEFEQLWKDIIHNPQVLSTQFTGVLQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRLYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTPWLCCALDPLGSAFPASPSSSSRPFALRAVQILDASKSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEAHVRQGVFNSLTHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPIEVKIEEPVSMEMDNHMSDKDDSCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETIVEEPVDITPFLDQLDESLKDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSGFSLLLDLLSELYQKQPKIGYHLLYYLKASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCYLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCTWQLFLAHSIPLEAIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWGLKHDDLLAEHIKALLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDSLRLNLANTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSSKPPHSVFPPISPPPPPRRHRCADFQTRDVNKGVSTKGWG", "length": 1039 }, "evidence": [ { "id": "E1BN70", "url": "https://omabrowser.org/oma/group/E1BN70/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7F730-1", "protein_name": "Integrator complex subunit 3 isoform X1", "gene_name": "Ints3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MELQKGKGTVAAAASGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTTGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQTLRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHLSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDVTPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEMREDFDSEQLSVLASCLQELFKAHFRGEVLPEEVTEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKALLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLANTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNTAQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1043 }, "evidence": [ { "id": "E1BN70", "url": "https://omabrowser.org/oma/group/E1BN70/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZUT9-1", "protein_name": "Integrator complex subunit 3", "gene_name": "Ints3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELQKGKGTVAAASSGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQLLMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQTLRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRSMLREKFPEFCSSPSPPVEASFPEASGILGSTRGYQESFFLYSQVKIEEPVSMEMDNHLSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDVTPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEVTEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETVIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKALLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLANTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNAAQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1066 }, "evidence": [ { "id": "E1BN70", "url": "https://omabrowser.org/oma/group/E1BN70/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SFW4-1", "protein_name": "Integrator complex subunit 3", "gene_name": "INTS3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELQKGKGAAAAAASGAAGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTTGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTTPLLALRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFEQLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHMSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDITPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSLLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNAAQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1040 }, "evidence": [ { "id": "E1BN70", "url": "https://omabrowser.org/oma/group/E1BN70/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1LXC9-1", "protein_name": "Integrator complex subunit 3", "gene_name": "ints3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPSPAKGKAQGRLLVSTSLDAKDELEERLERCMSITTSITNGLSEREANDALTAHVCKGPQQHEEVCLGLFTLLLTEPPQAQRCYRDLTLVNRDGMNVVLMKINQILMEKFLKLQDVCRTQLVWLVRELVKSGVIGADGVLMTLMKQIAGGDISSKNLWLAENVLDILVDQREWVLKSGMLVAMSLYTYLRLIVDHGTTSLLPLRQREVDFCIGLLRERFMECFIIGRDLVRLLQNVARIPEMELVWRDLLHSPQTLSPQFTGILQLLTSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTAESQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPHFFPPLEGQVRQGVFNSLNFIMEKRVLAHLAPLFDNPKLDRELRSMLRERFPEFCSSPSPPTEVKMEESVPLEMDNHVLDKEDGCYDNTDATFSDDEEELNNKGKKREFRFHQLKETYIDEPSDITPFVDQLDEALKERVLQLQKGSDTETHCEVMQEIVDLILEEDFDSEQMSTLASCLAELFKSHFRGDVLPEEITEESLEESVCKPVCLIFRNLCQMQEDNSGFSVLLDLLAELYQKQPKIGYHLLYYLKASKAASGKMSLYESFAQATALGDLHTCLMMDMKACQEDDVRLLCYLTPSIYSEFPDETLRSGELLNMIVAVIDSAQLQELMCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYSTWQLFLAHSIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPYHQEDQFTTSILRHWTAKHDDLLGEHIKALLIKNNNMPRKRQSLRSSSSKLAQLTLEQMLEHLDSLRLSLSNTKNNFFSQTPILQALQHVQASCDEAHKMRFSDLFSLAEEYEDSSKPPKSRRKAPASSPRSRKGAAPQPCNEEESVSSSASEEEDSKPKASKRKRKGSAVGSDSD", "length": 1017 }, "evidence": [ { "id": "E1BN70", "url": "https://omabrowser.org/oma/group/E1BN70/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q68E01-1", "protein_name": "Integrator complex subunit 3", "gene_name": "INTS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELQKGKGAAAAAAASGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGLPQHEEICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQALRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHMSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDITPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSLLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNATQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1043 }, "evidence": [ { "id": "E1BN70", "url": "https://omabrowser.org/oma/group/E1BN70/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7PLS8-1", "protein_name": "Integrator complex subunit 3", "gene_name": "IntS3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEQQQSKNNAHVSKLFICTAVDCKDDIEEKFERSFVTLQMQISGLSDKEMHDMLSQAVCKEKQHEEISIGFLYIMLTDPSMASKTYRDVTLVSRDGMNGIVTNLTFLVAEKYTKLTEVARRQLIWLLREFVKHQVLSVENVIWNCLRQAGGGDVSSRNLFLIESLLDIFIEFRTWLETNPFLVQSTVYSFVRLIEDHANPALLSLRQKEVKFTISLIRERFHDIIPLGRDFVRLLQNVARIPEFEQLWRDILFNPKMLHQTFNGIWQLLHIRTSRRFLQCRLLPEMERKISFLASSVKFGNQKRYQDWFQDKYFATPESHSLRSDLIRFIINVIHPTNDMLCSDIIPRWAIIGWLISSCTNPIASANAKLSLFYDWLFFDPAKDNIMNIEPGILVMYHSIRNHPFVSSTLLDFLCRITKNFFVKHEDKIRIGVYNSLKLILEKQVIPNLQPLFESPKLDRELRNLIRDNFREFLSPPANHGQLLFTSLHPVQGHILKKESDQRILHCENMDLHETGLINISGTIDEDKKILLVPTDQEIESVFSDETAENLRRVHNIEDNTDDDDDLPLSEVRLKEKPKVELAEAIAESFDAFVTKRNSYTWEAFLKDFRPLPASAFEEFQLNYVISNTVLILRETLPQQNIFSESKTEEKHLAKSISYPLYGLFRFLYENDEKSKKPFQTLLSEICEGIPEIGYLLLYFMKIYCKLQTRKNSQQSYQFKTTIYRQICDAADEKIGNCLLRDLDLLEKENTNIFLWLLPDIYREFKSIATNNTDLLRITLRCIDAKNVRDILYSIAQGKLTIFKQDGLIDCIRQSLEFETYEQFCLWQIVQAHDVPLRCIQDILPELEAGSHPEALSHFLLLLKNEEPTNEIIRLMLSRESKSKGDPFVTSALRFWCQRYEEKLSEIIASLLTSKYPSSSPNKRKRPPKGISVSTSTPSADQVLNHLEHYRRSCRHGTGTGLYVHDMMQRALQSAYSHSNDSTKKQFCDLFALAAEEDTTVGRRGGSGRGRKQPGSKKDVNNHGTSKKNPEMVKTIYSSDDNSSEEDWSKSKILQTAKRRKKANNDSD", "length": 1068 }, "evidence": [ { "id": "E1BN70", "url": "https://omabrowser.org/oma/group/E1BN70/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7TPD0-1", "protein_name": "Integrator complex subunit 3", "gene_name": "Ints3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELQKGKGTVAAAASGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQLLMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQTLRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRSMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHLSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDVTPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEVTEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKALLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLANTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNATQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1041 }, "evidence": [ { "id": "E1BN70", "url": "https://omabrowser.org/oma/group/E1BN70/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" }, { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" }, { "name": "mitotic G2/M transition checkpoint", "id": "GO:0044818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044818", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" }, { "name": "SOSS complex", "id": "GO:0070876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070876", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "E1BN70", "url": "https://www.uniprot.org/uniprotkb/E1BN70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" }, { "start_pos": 896, "end_pos": 898, "annotation": "n_glycosylation_sequon" }, { "start_pos": 931, "end_pos": 933, "annotation": "n_glycosylation_sequon" }, { "start_pos": 998, "end_pos": 1000, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN70-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1040, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN70-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN70" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN70" }, { "id": "PF10189", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10189" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 3 N-terminal", "eco_id": "ECO_0000259", "start_pos": 83, "end_pos": 489, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BN70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN70" }, { "id": "PF24566", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24566" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ints3-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 580, "end_pos": 971, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 664, "end_pos": 666 }, { "start_pos": 896, "end_pos": 898 }, { "start_pos": 931, "end_pos": 933 }, { "start_pos": 998, "end_pos": 1000 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BN87-1", "uniprot_ac": "E1BN87", "uniprot_id": "E1BN87_BOVIN", "mass": { "chemical_mass": 32348.0, "monoisotopic_mass": 32348.0 }, "refseq": { "ac": "NP_001179878", "name": "forkhead box protein I2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179878" }, "gene_names": [ { "name": "FOXI2", "type": "recommended", "evidence": [ { "id": "E1BN87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN87" } ] }, { "name": "FOXI2", "type": "synonym", "evidence": [ { "id": "NP_001179878", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179878" } ] } ], "protein_names": [ { "name": "Forkhead box protein L2", "type": "recommended", "evidence": [ { "id": "E1BN87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN87/entry#names_and_taxonomy" } ] }, { "name": "forkhead box protein I2", "type": "synonym", "evidence": [ { "id": "NP_001179878", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179878" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN87", "url": "https://www.uniprot.org/uniprotkb/E1BN87" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FOXI2", "url": "https://www.uniprot.org/uniprotkb/E1BN87", "locus": { "chromosome": "26", "start_pos": 47191278, "end_pos": 47189667, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006218", "url": "https://www.ensembl.org/id/ENSBTAG00000006218" } ] } } ], "crossref": [ { "id": "E1BN87", "url": "https://alphafold.ebi.ac.uk/entry/E1BN87", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006218", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006218", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20053", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20053", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "613373", "url": "https://www.ncbi.nlm.nih.gov/gene/613373", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613373", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613373", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MATYCKD", "url": "https://omabrowser.org/oma/group/MATYCKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN87", "url": "https://www.orthodb.org/?gene=E1BN87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11829:SF372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829:SF372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179878", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179878", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BN87", "url": "https://www.uniprot.org/uniprotkb/E1BN87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN87-1", "url": "https://www.uniprot.org/uniprotkb/E1BN87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEYGDGSGPSAAPQSQARAAARPSGYARGDLGAAGAGPRLWLNAPALSSAPYAPGPVPAAPFGAPGPLLAAPGGLAGADLAWLSLPGQQELLRLVRPPYSYSALIAMAIQSAPRRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRGEAGAVAPSGPRSQAGARAPELEPLGAASPDLRASASPPAPEAAACFSSLASAVGALAGGFNPLPGGLAGDFSFGRPATIATHSPQVPRPAPGFAAGQQTAATGFRVSHFVYTREGTEV", "length": 312, "header": "tr|E1BN87-1|E1BN87_BOVIN Isoform 1 of Forkhead box protein L2 OS=Bos taurus OX=9913 GN=FOXI2 PE=4 SV=1 CANONICAL=E1BN87-1" }, "isoforms": [ { "isoform_ac": "E1BN87-1", "url": "https://www.uniprot.org/uniprotkb/E1BN87/entry#E1BN87-1", "sequence": { "sequence": "MAEYGDGSGPSAAPQSQARAAARPSGYARGDLGAAGAGPRLWLNAPALSSAPYAPGPVPAAPFGAPGPLLAAPGGLAGADLAWLSLPGQQELLRLVRPPYSYSALIAMAIQSAPRRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRGEAGAVAPSGPRSQAGARAPELEPLGAASPDLRASASPPAPEAAACFSSLASAVGALAGGFNPLPGGLAGDFSFGRPATIATHSPQVPRPAPGFAAGQQTAATGFRVSHFVYTREGTEV", "length": 312, "header": "tr|E1BN87-1|E1BN87_BOVIN Isoform 1 of Forkhead box protein L2 OS=Bos taurus OX=9913 GN=FOXI2 PE=4 SV=1 CANONICAL=E1BN87-1" }, "locus": { "chromosome": "26", "start_pos": 47191275, "end_pos": 47189667, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008160.5", "url": "https://www.ensembl.org/id/ENSBTAT00000008160.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008160.4", "url": "https://www.ensembl.org/id/ENSBTAP00000008160.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:613373", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613373", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q63248-1", "protein_name": "Forkhead box protein I2", "gene_name": "Foxi2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LVRPPYSYSALIAMAIQSAPRRRLTLSQIYQYVAGNFPFYKRTKAGWQNSIRHNLSLNDCFKKVPRDENDPGKGNYWMLDPNCEKMFDNGNFRRKRRRRGE", "length": 101 }, "evidence": [ { "id": "E1BN87", "url": "https://omabrowser.org/oma/group/E1BN87/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZQN5-1", "protein_name": "Forkhead box protein I2", "gene_name": "FOXI2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATYCDDLGPSSAPPGQAQATAHPPGYEPGDLGAVGGGPLLWVNAPALSPKSYASGPGPAPPYAAPSYGAPGPLLGAPGGLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRAEASAAVRSGARSVGGAEAPALEPPSAACLDLQASPSPSAPEAATCFSGFASAMSALAGGLGTFPGGLAGDFSFGRRPPTVATHAPQTLNPSPGFAPGHQTAAAGFRLSHLLYSREGTEV", "length": 318 }, "evidence": [ { "id": "E1BN87", "url": "https://omabrowser.org/oma/group/E1BN87/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BN87", "url": "https://www.uniprot.org/uniprotkb/E1BN87" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BN87", "url": "https://www.uniprot.org/uniprotkb/E1BN87" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BN87", "url": "https://www.uniprot.org/uniprotkb/E1BN87" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BN87", "url": "https://www.uniprot.org/uniprotkb/E1BN87" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "E1BN87", "url": "https://www.uniprot.org/uniprotkb/E1BN87" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "E1BN87", "url": "https://www.uniprot.org/uniprotkb/E1BN87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BN87", "url": "https://www.uniprot.org/uniprotkb/E1BN87" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BN87", "url": "https://www.uniprot.org/uniprotkb/E1BN87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN87-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN87-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN87" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN87" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 191, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BN90-1", "uniprot_ac": "E1BN90", "uniprot_id": "E1BN90_BOVIN", "mass": { "chemical_mass": 110635.0, "monoisotopic_mass": 110635.0 }, "refseq": { "ac": "NP_001192599", "name": "zinc finger protein with KRAB and SCAN domains 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192599" }, "gene_names": [ { "name": "ZKSCAN2", "type": "recommended", "evidence": [ { "id": "E1BN90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN90" } ] }, { "name": "ZKSCAN2", "type": "synonym", "evidence": [ { "id": "NP_001192599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192599" } ] } ], "protein_names": [ { "name": "Zinc finger with KRAB and SCAN domains 2", "type": "synonym", "evidence": [ { "id": "E1BN90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN90/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein with KRAB and SCAN domains 2", "type": "synonym", "evidence": [ { "id": "NP_001192599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192599" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "E1BN90", "url": "https://www.uniprot.org/uniprotkb/E1BN90#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN90", "url": "https://www.uniprot.org/uniprotkb/E1BN90" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZKSCAN2", "url": "https://www.uniprot.org/uniprotkb/E1BN90", "locus": { "chromosome": "25", "start_pos": 22823013, "end_pos": 22836833, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011162", "url": "https://www.ensembl.org/id/ENSBTAG00000011162" } ] } } ], "crossref": [ { "id": "E1BN90", "url": "https://alphafold.ebi.ac.uk/entry/E1BN90", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011162", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011162", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539463", "url": "https://www.ncbi.nlm.nih.gov/gene/539463", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539463", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539463", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KHREVHV", "url": "https://omabrowser.org/oma/group/KHREVHV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN90", "url": "https://www.orthodb.org/?gene=E1BN90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13837", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192599", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BN90", "url": "https://www.uniprot.org/uniprotkb/E1BN90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN90-1", "url": "https://www.uniprot.org/uniprotkb/E1BN90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASLDPQTDAPLEVEGCLIMKVEKEPEWISEPTLEGSDSSESETFRRCFRQFCYEDVTGPHEAFSKLWELCCRWLKPEMRSKEQILELLVIEQFLTILPEKIQLWAQKQCPESGEEAVALVIHLEKETGGLRQQVSSPVHSEKQAPLGAAWEVADFQPQPVEPQPRVMSQEEAESLHSGRQEQPNQKRELRPLPKNARPSPWVPSPANEWNTIDQEVTATPVPVRSQGPVKDVHMARGFSYKKSVHQIPAHKDLYRDIRKESVGNMVSLGSTVSAANKIARLEPRKEPWTISLQSSNKRTVLQSNYIKEKSVHAIQIPARNAGKTWREQQQWGLEDEKIAGVHWSYEETKTFLAILKESRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHVLEPCAFFEDMDALLNPSAHASSMDKPKEILSLPRLKRIGISAKEQINLVEEEEAAEESDGDEMGIEFIRKPELHGAPVIFQNLSGVHWGYEETKTFLDILHETRFYEALQACHRKSKLYGAVAEQLRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALINSRASAAPTSSPEEAPSPSVQEREDMEIEPQEPTVWEPEEDSQEVLVEDSGSERMSEEEIMQEPEFQGPPCLLQSPSDFEIESSIKEDATQVICKDMEQHRAFIEKSKRVVSQNVDPGKYCKRDCVSGGQWENLHGIRQGKLMPQPRDLGKAVVHQRPLVGKRPFRLLRYGESFGRSARLMCRMTHQKENPSKCSVCGKCFGRSRSLVRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHQRIHTGEKPYRCGECGKCFSQSSSLIIHQRTHTGEKPYQCGDCGRSFTNSSHFSAHRRVHTGENPYKCVDCEKSFNNCTRFREHRRVHSGEKPYGCSQCGRRFSKSSVLTKHREVHVREKLLPPPPAFCSPENPLKGKTDDFRQTL", "length": 969, "header": "tr|E1BN90-1|E1BN90_BOVIN Isoform 1 of Zinc finger with KRAB and SCAN domains 2 OS=Bos taurus OX=9913 GN=ZKSCAN2 PE=3 SV=1 CANONICAL=E1BN90-1" }, "isoforms": [ { "isoform_ac": "E1BN90-1", "url": "https://www.uniprot.org/uniprotkb/E1BN90/entry#E1BN90-1", "sequence": { "sequence": "MAASLDPQTDAPLEVEGCLIMKVEKEPEWISEPTLEGSDSSESETFRRCFRQFCYEDVTGPHEAFSKLWELCCRWLKPEMRSKEQILELLVIEQFLTILPEKIQLWAQKQCPESGEEAVALVIHLEKETGGLRQQVSSPVHSEKQAPLGAAWEVADFQPQPVEPQPRVMSQEEAESLHSGRQEQPNQKRELRPLPKNARPSPWVPSPANEWNTIDQEVTATPVPVRSQGPVKDVHMARGFSYKKSVHQIPAHKDLYRDIRKESVGNMVSLGSTVSAANKIARLEPRKEPWTISLQSSNKRTVLQSNYIKEKSVHAIQIPARNAGKTWREQQQWGLEDEKIAGVHWSYEETKTFLAILKESRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHVLEPCAFFEDMDALLNPSAHASSMDKPKEILSLPRLKRIGISAKEQINLVEEEEAAEESDGDEMGIEFIRKPELHGAPVIFQNLSGVHWGYEETKTFLDILHETRFYEALQACHRKSKLYGAVAEQLRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALINSRASAAPTSSPEEAPSPSVQEREDMEIEPQEPTVWEPEEDSQEVLVEDSGSERMSEEEIMQEPEFQGPPCLLQSPSDFEIESSIKEDATQVICKDMEQHRAFIEKSKRVVSQNVDPGKYCKRDCVSGGQWENLHGIRQGKLMPQPRDLGKAVVHQRPLVGKRPFRLLRYGESFGRSARLMCRMTHQKENPSKCSVCGKCFGRSRSLVRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHQRIHTGEKPYRCGECGKCFSQSSSLIIHQRTHTGEKPYQCGDCGRSFTNSSHFSAHRRVHTGENPYKCVDCEKSFNNCTRFREHRRVHSGEKPYGCSQCGRRFSKSSVLTKHREVHVREKLLPPPPAFCSPENPLKGKTDDFRQTL", "length": 969, "header": "tr|E1BN90-1|E1BN90_BOVIN Isoform 1 of Zinc finger with KRAB and SCAN domains 2 OS=Bos taurus OX=9913 GN=ZKSCAN2 PE=3 SV=1 CANONICAL=E1BN90-1" }, "locus": { "chromosome": "25", "start_pos": 22836634, "end_pos": 22824017, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014826.4", "url": "https://www.ensembl.org/id/ENSBTAT00000014826.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014826.2", "url": "https://www.ensembl.org/id/ENSBTAP00000014826.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539463", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539463", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZXU0-1", "protein_name": "Zinc finger with KRAB and SCAN domains 2", "gene_name": "Zkscan2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATVINPQMDVEVEECLIMKVEKDSGWASEPILERSDSTECESFRKCFRQFCYEDVTGPHEAFSKLWELCCRWLKPEMRSKEQILEQLVIEQFLTILPEKIQAWAQRQCPESGEEAVALVVHLEKETRRLRKQVSGPQHSEKQAPPRTVWEVANYEPEQLETQHRVVSREEAGNFHSGHQEQLNQKREHRPLPKNAHSSVWAPVPSSEWTAVDEEATTQEPVRDIHTVRSFPYKRSVQQVPAHRDLYHEIRKESACSVVSLGDTVSAPNKIAQLEQKKEPWTVGLHSSNKRTSVLQSKISKEKSVHAVQIPARNAGKVWREQQQWGLEDEKIAGVHWSYEETKTFLAILKESRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHMLEPCAFFEDMDALLNPEAHTSSTERPKAVISLPLKRTAVSAKEQVSLVEEEEGAEDSDGDEVGIEFVRKSEIRAAPILFQNLSGVHWGYEETKTFLDILQETRFYEALQACHRKSKLYGVVAEQLRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALVNCRTAALPTNTSEEIPSLSRQERGHIEVEPQEPTTWEPEESSQEAVLEDSGSERMSEEEITEEPEFEGSAGLPQSPTDFEIGNIIKEAPTQVIFKDTESHRALIEKPKRFVSQNTNPSKYGKRECFSGRHWENLQGVRQGKLMSQPRDTGKAVVHQRPFVGRRPYRLLKYGENFGRSARLVCRMTHQKENPYKCGVCGKCFGRSRSLIRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHLRIHTGEKPYRCRECGKCFSQSSSLIIHQRTHTGEKPYQCEECGKSFTNSSHFSAHRRAHTGENPYKCGDCEKSFNNCTRFREHRRIHTGEKPYTCAQCGKHFNKSSFLTKHREIHIREKPLPYSPSVYSPENLLKARSAELRKTF", "length": 960 }, "evidence": [ { "id": "E1BN90", "url": "https://omabrowser.org/oma/group/E1BN90/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X952-1", "protein_name": "Zinc finger with KRAB and SCAN domains 2", "gene_name": "Zkscan2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVMNPQIDVEVEECLIMKVEKDSEWVSEPILERSGSTECESFRKCFRQFCYEDVTGPHEAFSKLWELCCRWLKPEMRSKEQILEQLVIEQFLTILPEKIQTWAQKQCPESGEEAVALVVHLEKETRRLRKQVSSPLPSEKQAPPRTVWEVADFEPEQLETQHRVVSLEEAGSLHSGHQEQLNQKREHRPLPKNAHSSVWVPVPSDEWNALDEEVTTQEPIRDVHTERSFSYKKSVQQVPAHRGLYHEIRKESAGSMVSLGDSVSAPNKIAQLEQKKEPWSVGLHSSNKRNSVLQSNYIKEKSVHAVQIPARNAGKVWREQQQWGLEDEKIAGVHWSYEETKTFLAILKESRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHMLEPCAFFEDMDALLNPAAHTSSTERPKVVISLPLKRTAISAKEQVSLVEEEEGAEDSDGDEVGIEFIRKSEIRAAPVLFQNLSGVHWGYEETKTFLDILQETRFYEALQACHRKSKLYGVVAEQLRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALVNCRPSSLSTNTSEEVPSLSRQERGHIEVEPREPTTWEPVETPQEAVLEDSGSERLSEEEMIEEPELEGPSGLLQSPAGFEIGTIIKEDPTQVMFKDTEPHRVLMEKPKRLVSQNTNPSKYCKREYFSGRHCENLQGVRQGKLMSQPRDTGKAVVHQRPCVGRRPYRLLKYGENFGRSARLVCRMTHQKENPFKCGVCGKCFGRSRSLIRHQRIHTGEKPFKCPDCGKSFNDSSNFGAHQRVHTGEKPYRCRECGKCFSQSSSLIIHQRTHTGEKPYQCEECGKSFTNSSHFSAHRRIHTEENPYKCGDCEKSFNNCARFREHQRIHNGEKPYTCAQCGKHFNKSSFLTKHREVHMREKLLPYSPSVYSPENLLKGKSAELRKTF", "length": 960 }, "evidence": [ { "id": "E1BN90", "url": "https://omabrowser.org/oma/group/E1BN90/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3LVD4-1", "protein_name": "Zinc finger with KRAB and SCAN domains 2", "gene_name": "ZKSCAN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAASLDPQIHASLEAEGCLIMKVEKEPEWASEPILEGSDGSECETFRKCFRQFCYDDVTGPHEAFSKLWELCCRWLKPEMRSKEQILELLVIEQFLTILPEKIQAWAQKQCPESGEEAVALVIHLEKENRRLRQQVSSPVHSEKQVPVGAAWEVADFEPEQVETQPRLMSQEEVERLHSGHQEPLNQKRELRPLPKNAQPSPWVPAPADDWNTMAQEVTATQLPVGSQRPGKDIHMARGFPYKKSVHQIPAHRDLCGDIRKESVGNMVSLGSTVTTSNKIPRVEQRKEPWTIGLHSSSKRNILRSSYVKEKPVPALQVPARNAGKTWREQQQWGLEDEKIAGVHWSYEETKTFLAILKESRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHVLEPCAFFEDMDALLNPTAHASSTDKPKEILSLPRLKRISISAKERINLVEEEDAAEESDGDEMGVEFIRKSELHGAPVLFQNLSGVHWGYEETKTFLEILRETRFYEALQACHRKSKLYGAVAEQLRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALINSRVPAPPAGTPEEVPSPSFQEREDIEIEPQEPVGWEPEEASQEAVVEDSGSERMSEEEIVQEPEFLGPPGLLQSPHDFEIGSSFNEDATQVIYKDLEQHRALIEKAKRVVSQNADPGKHHKRECISGRQWENLQGIRQGKPMAQPRDLGKAVVHQRPFLGKRPYRLLRYGEGFGRSARLLCRMPHQKENPYKCSVCGKCFGRSRSLIRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHQRIHTGEKPYRCGECGKCFSQSSSLIIHQRTHTGEKPYQCGECGKSFTNSSHFSAHRRVHTGENPYKCADCEKSFNNCTRFREHRRIHTGEKPYGCAQCGKRFSKSSVLAKHREVHTREKLLPHPPALYSPENPQKGKTDQFRTSF", "length": 969 }, "evidence": [ { "id": "E1BN90", "url": "https://omabrowser.org/oma/group/E1BN90/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q63HK3-1", "protein_name": "Zinc finger protein with KRAB and SCAN domains 2", "gene_name": "ZKSCAN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVALDSQIDAPLEVEGCLIMKVEKDPEWASEPILEGSDSSETFRKCFRQFCYEDVTGPHEAFSKLWELCCRWLKPEMRSKEQILELLVIEQFLTILPEKIQAWAQKQCPQSGEEAVALVVHLEKETGRLRQQVSSPVHREKHSPLGAAWEVADFQPEQVETQPRAVSREEPGSLHSGHQEQLNRKRERRPLPKNARPSPWVPALADEWNTLDQEVTTTRLPAGSQEPVKDVHVARGFSYRKSVHQIPAQRDLYRDFRKENVGNVVSLGSAVSTSNKITRLEQRKEPWTLGLHSSNKRSILRSNYVKEKSVHAIQVPARSAGKTWREQQQWGLEDEKIAGVHWSYEETKTFLAILKESRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHMLEPCAFFEDMDALLNPAARAPSTDKPKEMIPVPRLKRIAISAKEHISLVEEEEAAEDSDDDEIGIEFIRKSEIHGAPVLFQNLSGVHWGYEETKTFLDILRETRFYEALQACHRKSKLYGAVAEQLRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALINSRASAPSPSTPEEVPSPSRQERGGIEVEPQEPTGWEPEETSQEAVIEDSCSERMSEEEIVQEPEFQGPPGLLQSPNDFEIGSSIKEDPTQIVYKDMEQHRALIEKSKRVVSQSTDPSKYRKRECISGRQWENLQGIRQGKPMSQPRDLGKAVVHQRPFVGKRPYRLLKYGESFGRSTRLMCRMTHHKENPYKCGVCGKCFGRSRSLIRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHQRIHTGEKPYRCGECGKCFSQSSSLIIHQRTHTGEKPYQCGECGKSFTNSSHFSAHRRVHTGENPYKCVDCEKSFNNCTRFREHRRIHTGEKPYGCAQCGKRFSKSSVLTKHREVHVREKPLPHPPSLYCPENPHKGKTDEFRKTF", "length": 967 }, "evidence": [ { "id": "E1BN90", "url": "https://omabrowser.org/oma/group/E1BN90/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BN90", "url": "https://www.uniprot.org/uniprotkb/E1BN90" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BN90", "url": "https://www.uniprot.org/uniprotkb/E1BN90" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BN90", "url": "https://www.uniprot.org/uniprotkb/E1BN90" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BN90", "url": "https://www.uniprot.org/uniprotkb/E1BN90" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BN90", "url": "https://www.uniprot.org/uniprotkb/E1BN90" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BN90", "url": "https://www.uniprot.org/uniprotkb/E1BN90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 815, "end_pos": 817, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" }, { "start_pos": 900, "end_pos": 902, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN90-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 969, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN90-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN90" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN90" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 777, "end_pos": 804, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BN90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN90" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 302, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BN90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN90" }, { "id": "PS50804", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50804" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCAN box", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 128, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 496, "end_pos": 498 }, { "start_pos": 815, "end_pos": 817 }, { "start_pos": 872, "end_pos": 874 }, { "start_pos": 900, "end_pos": 902 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNA4-1", "uniprot_ac": "E1BNA4", "uniprot_id": "E1BNA4_BOVIN", "mass": { "chemical_mass": 135696.0, "monoisotopic_mass": 135696.0 }, "refseq": { "ac": "NP_001192915", "name": "VPS10 domain-containing receptor SorCS3 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192915" }, "gene_names": [ { "name": "SORCS3", "type": "recommended", "evidence": [ { "id": "E1BNA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA4" } ] }, { "name": "SORCS3", "type": "synonym", "evidence": [ { "id": "NP_001192915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192915" } ] } ], "protein_names": [ { "name": "VPS10 domain-containing receptor SorCS3", "type": "recommended", "evidence": [ { "id": "E1BNA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA4/entry#names_and_taxonomy" } ] }, { "name": "VPS10 domain-containing receptor SorCS3 precursor", "type": "synonym", "evidence": [ { "id": "NP_001192915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192915" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNA4", "url": "https://www.uniprot.org/uniprotkb/E1BNA4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SORCS3", "url": "https://www.uniprot.org/uniprotkb/E1BNA4", "locus": { "chromosome": "26", "start_pos": 26182512, "end_pos": 25203123, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004612", "url": "https://www.ensembl.org/id/ENSBTAG00000004612" } ] } } ], "crossref": [ { "id": "E1BNA4", "url": "https://alphafold.ebi.ac.uk/entry/E1BNA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004612", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004612", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "531405", "url": "https://www.ncbi.nlm.nih.gov/gene/531405", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:531405", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531405", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RRNDGNC", "url": "https://omabrowser.org/oma/group/RRNDGNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNA4", "url": "https://www.orthodb.org/?gene=E1BNA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12106:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12106:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192915", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192915", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BNA4", "url": "https://www.uniprot.org/uniprotkb/E1BNA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNA4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAARTERAAGWPGAPLARTGLLLLSTWVLAGAEITWDTTGGPGRLAALASRSPALPRLSPLAVASQWPEELATVRRGAALERRPGPEPLPQPSSGSGGKKQGEAGGLSPASSRWGPGISTPGKPSGVRRSRRAQPPSALEHGDARATVLADGSKGSRPLAKGLREEVKAPRTAGSAAEELRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRSTDYGTTYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEIESSILISSDEGATYQKYRLTFYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADLVHMEVRTADGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTGGRASYYVSYRREAFAQIKLPKYSLPKDMHIISTNENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKSSRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDMDLRGNPVHCLLPFCSLHLHLQISENPYSSGRISSKETAPGLVVATGNIGLELSYTDISVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALVEAGVETQIMTVFGHFSLRSEWQLVKVDYKSIFSRHCSKEDYQTWHLLNQGEPCVMGERKIFKKRKPGAQCALGRDSSGTVVSEPCVCADWDFECDYGYERHGESQCVPAFWYNPASPSKDCSLGQSYFNSTGYRRIVSNKCTDGLREKYTAKAQMCPGKAPHGLHVATTDGRLVAEQGHNATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAYAENNLGSDTAVLFLHVVCPVEHVHLRVPFVAIRKKEVNISAVVWPSQLGTLTYFWWFGNSTKPLITLDSSISFTFLAEGTNTITVQVAAGNALIQDTKDIAVHEYFQSQLLSFSPNLDYHNPDIPEWRQDIANVIKRALVKVTSVPEDQILVAVFPGLPTSAELFILPPKNLTERRKGNEGDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSGAGHSSSAMLMLLSVVFVGLAVFLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDKELDSRVIGGIATIANSESTKEIPNCTSV", "length": 1222, "header": "tr|E1BNA4-1|E1BNA4_BOVIN Isoform 1 of VPS10 domain-containing receptor SorCS3 OS=Bos taurus OX=9913 GN=SORCS3 PE=3 SV=3 CANONICAL=E1BNA4-1" }, "isoforms": [ { "isoform_ac": "E1BNA4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNA4/entry#E1BNA4-1", "sequence": { "sequence": "MEAARTERAAGWPGAPLARTGLLLLSTWVLAGAEITWDTTGGPGRLAALASRSPALPRLSPLAVASQWPEELATVRRGAALERRPGPEPLPQPSSGSGGKKQGEAGGLSPASSRWGPGISTPGKPSGVRRSRRAQPPSALEHGDARATVLADGSKGSRPLAKGLREEVKAPRTAGSAAEELRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRSTDYGTTYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEIESSILISSDEGATYQKYRLTFYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADLVHMEVRTADGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTGGRASYYVSYRREAFAQIKLPKYSLPKDMHIISTNENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKSSRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDMDLRGNPVHCLLPFCSLHLHLQISENPYSSGRISSKETAPGLVVATGNIGLELSYTDISVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALVEAGVETQIMTVFGHFSLRSEWQLVKVDYKSIFSRHCSKEDYQTWHLLNQGEPCVMGERKIFKKRKPGAQCALGRDSSGTVVSEPCVCADWDFECDYGYERHGESQCVPAFWYNPASPSKDCSLGQSYFNSTGYRRIVSNKCTDGLREKYTAKAQMCPGKAPHGLHVATTDGRLVAEQGHNATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAYAENNLGSDTAVLFLHVVCPVEHVHLRVPFVAIRKKEVNISAVVWPSQLGTLTYFWWFGNSTKPLITLDSSISFTFLAEGTNTITVQVAAGNALIQDTKDIAVHEYFQSQLLSFSPNLDYHNPDIPEWRQDIANVIKRALVKVTSVPEDQILVAVFPGLPTSAELFILPPKNLTERRKGNEGDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSGAGHSSSAMLMLLSVVFVGLAVFLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDKELDSRVIGGIATIANSESTKEIPNCTSV", "length": 1222, "header": "tr|E1BNA4-1|E1BNA4_BOVIN Isoform 1 of VPS10 domain-containing receptor SorCS3 OS=Bos taurus OX=9913 GN=SORCS3 PE=3 SV=3 CANONICAL=E1BNA4-1" }, "locus": { "chromosome": "26", "start_pos": 26181293, "end_pos": 25203123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010450.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010450.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010450.6", "url": "https://www.ensembl.org/id/ENSBTAP00000010450.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:531405", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531405", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZBW7-1", "protein_name": "VPS10 domain-containing receptor SorCS1", "gene_name": "SORCS3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEKGTNCFPTCHTVFLAWTWLLLLSWCCTGAEITCRSCSSPSPSWPSSSPRLRQEQRQTPPPTPRGLRSWPGGRARGSAGAAVTAEPLPGGESGGRAGPRGAELLSAGAGGGAAGSRGSAAPRSRRSSEGRPVEGGGRGMPAAEGQRSARAQPRGPPEEGRAARLRGVEELRLGSTTFALTGDAAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRSTDYGTTYEKLNDKVGLKTVLSYFYVCPTNKRKIMLLSDPDIESSILISSDEGATYQKYRLNFYIQSLLFHPKQEEWILAYSLDQKLYSSTDFGRKWQLMHERVTPSRFYWSVMGLDKEPDLVHMEARTADGHTHYLTCRIQECSETKRSGPFSRSIDINSLVVQDEYIFIQVTAGGRANYYVSYRREPFAQIKLPKYSLPKDMHIISTAENQVFAAVQEWNQNDTYNLYVSDTRGVYFTLALENVKSSRGLEGNVMIDLYEVAGIKGIFLANKKIDDQVKTFITYNKGRDWRLLKAPDTNLRGDPVVCQLPFCSLHLHLQLSENPYTSGSISSKETAPGLMVAAGNIGSELSYTDVGMFISSDGGNSWRQIFEEEYNVWFLDWGGALVALKHTSMPIRHLWVSFDEGRSWSKYSFTSTPLFVDGSLVDPGIETQIMTIFGHFSLRSEWQLVKVDYKPIFSRRCNKDDYQTWHLHNQGEPCVMGERKIYKKRKPGSQCSVGRDYSQTVVSEPCVCGQGDFECDYGYERHNNNQCIPSFWFSPSSLSKDCSIGQSYLNSTGYRRIVSNNCTDGLREKYKARMEKCPGKAPRGLHILTSDGKLVTEQGHNATFIILMEEGDLQRTNIQLDFGDGITVSYANFSPVEDGIRHVYKSAGIFQVTAYAENSLGSDTAVLFLHVVCPVEHVHLSVPFVAIRNKDVNITAVVWPSQAGTLTYFWWFGNSTKPLITLESSISYIFNEEGMNTVTVQVAAGNTLIQDTKEIAVHEYFQSQLLSFSPNLDYHNPDIPEWRQDIGKVIRRALAQVTGIPDEQILVAVFPGLPTSAELFVLPHKNTTERRKSSEADLEQVVEILFNALNQNLVQFELKPGVEVIVYVTQLTLAPLVDSSTGHSSSAMLMLLSVVFVGLAVFLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSEFTDPEELMDKELDTRVMGSISTIANSESTKEIPNCTSV", "length": 1212 }, "evidence": [ { "id": "E1BNA4", "url": "https://omabrowser.org/oma/group/E1BNA4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A2I9-1", "protein_name": "VPS10 domain-containing receptor SorCS3", "gene_name": "Sorcs3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESAGTERPAGWPGAPLARTGLLLLSTWVLAGAEITWGATGGPGRLVSPASRPPALPPLLPRAAENRWPEELASARRAAAPRRRSRLELLSQASRGEIPTEAAGTSPEGARWVRGIPAPSQAGSARRTRRAQPPSTLERGDAWATAPADGAKGNRPQTKGSREEVKATLTGGSATEELRLPSTSFALTGDSAHNQAMVHWFGHNSSVILILTKLYDFNLGSVTESSLWRSVDYGATYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGTTYQKYRLTFYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVSGLDKEADLVHMEVRSADGYAHYLTCRIQECTETTRSGPFARSIDISSLVVQDEYIFIQVTIGGRASYYVSYRREAFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKSSRSLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDLRGSPVHCLLPFCSLHLHLQLSENPYSSGRISSKDTAPGLVVATGNIGSELSYTDIGVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTLLPLFVDGALVEAGIETHIMTVFGHFNLRSEWQLVKVDYKSIFSRRCTKEDFETWHLLNQGEPCVMGERKIFKKRKPGAQCALGREYSGSVTSEPCVCADWDFECDYGYERHGESQCVPAFWYNPASPSKDCSLGQSYLNSTGYRRIVSNNCTDGLRDKYSAKTQLCPGKAPRGLHVVTTDGRLVAEQGHNATFIILMEEGDLQRTNIQLDFGDGVAVSYANFSPIEDGIRHVYKSAGIFQVTAYAENNLGSDTAFLFLHVVCPVEHVHLQVPFVAIRNKDVNISAVVWPSQLGTLTYFWWFGNSTKPLITLDSSISFTFLAEGTNTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYHNPDIPEWRQDIGNVIKRALIKVTSVPEDQILVAVFPGLPTSAELFILPPKNLTERRKGHEGDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVVFVGLAVFLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELMDKELDTRVIGSIATIASSESTKEIPNCTSV", "length": 1219 }, "evidence": [ { "id": "E1BNA4", "url": "https://omabrowser.org/oma/group/E1BNA4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VI51-1", "protein_name": "VPS10 domain-containing receptor SorCS3", "gene_name": "Sorcs3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAAGTERPAGWPGAPLARTGLLLLSTWVLAGAEITWGATGGPGRLVSPASRPPVLPPLLPRAAENRWPEELASARRAAAPRRRSRLEPLSQASRGEIRTEAAGMSPEGARWVPGIPSPSQAGSARRTRRAQPPSPLERGDSWATALADGAKGSRPHTKGSREEVRATRTGGASTEELRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRSVDYGATYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSVLISSDEGATYQKYRLTFYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVSGLDKEADLVHMEVRTADGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTIGGRASYYVSYRREAFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKSSRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDLRGSPVHCLLPFCSLHLHLQLSENPYSSGRISSKDTAPGLVVATGNIGSELSYTDIGVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTLLPLFVDGALVEAGVETHIMTVFGHFSLRSEWQLVKVDYKSIFSRRCTKEDFETWHLLNQGEPCVMGERKIFKKRKPGAQCALGREYSGSVVSEPCVCADWDFECDYGYERHGESQCVPAFWYNPASPSKDCSLGQSYLNSTGYRRIVSNNCTDGLRDKYSAKTQLCPGKAPRGLHVVTTDGRLVAEQGHNATFIILMEEGDLQRTNIQLDFGDGVAVSYANFSPIEDGIRHVYKSAGIFQVTAYAENNLGSDTAFLFLHVVCPVEHVHLRVPFVAIRNKDVNISAVVWPSQLGTLTYFWWFGNSTKPLITLDSSISFTFLAEGTNTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYHNPDIPEWRQDIGNVIKRALIKVTSVPEDQILVAVFPGLPTSAELFILPPKNLTERRKGHEGDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVVFVGLAVFLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDKELDTRVIGSIATIASSESTKEIPNCTSV", "length": 1219 }, "evidence": [ { "id": "E1BNA4", "url": "https://omabrowser.org/oma/group/E1BNA4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UPU3-1", "protein_name": "VPS10 domain-containing receptor SorCS3", "gene_name": "SORCS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAARTERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPASRPPALSPLSPRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAAEDLRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRSTDYGTTYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGATYQKYRLTFYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADLVHMEVRTTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYYVSYRREAFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKSSRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDLRGSPVHCLLPFCSLHLHLQLSENPYSSGRISSKETAPGLVVATGNIGPELSYTDIGVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALVEAGMETHIMTVFGHFSLRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEPCVMGERKIFKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYERHGESQCVPAFWYNPASPSKDCSLGQSYLNSTGYRRIVSNNCTDGLREKYTAKAQMCPGKAPRGLHVVTTDGRLVAEQGHNATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAYAENNLGSDTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNSTKPLITLDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYHNPDIPEWRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERRKGNEGDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVVFVGLAVFLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDKELDTRVIGGIATIANSESTKEIPNCTSV", "length": 1222 }, "evidence": [ { "id": "E1BNA4", "url": "https://omabrowser.org/oma/group/E1BNA4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "E1BNA4", "url": "https://www.uniprot.org/uniprotkb/E1BNA4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "E1BNA4", "url": "https://www.uniprot.org/uniprotkb/E1BNA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1065, "end_pos": 1067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1218, "end_pos": 1220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 840, "end_pos": 842, "annotation": "n_glycosylation_sequon" }, { "start_pos": 871, "end_pos": 873, "annotation": "n_glycosylation_sequon" }, { "start_pos": 932, "end_pos": 934, "annotation": "n_glycosylation_sequon" }, { "start_pos": 953, "end_pos": 955, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNA4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1222, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNA4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNA4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA4" }, { "id": "PS50093", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PKD", "eco_id": "ECO_0000259", "start_pos": 860, "end_pos": 904, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1065, "end_pos": 1067 }, { "start_pos": 1218, "end_pos": 1220 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 789, "end_pos": 791 }, { "start_pos": 840, "end_pos": 842 }, { "start_pos": 871, "end_pos": 873 }, { "start_pos": 932, "end_pos": 934 }, { "start_pos": 953, "end_pos": 955 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNB3-1", "uniprot_ac": "E1BNB3", "uniprot_id": "E1BNB3_BOVIN", "mass": { "chemical_mass": 47724.0, "monoisotopic_mass": 47724.0 }, "refseq": {}, "gene_names": [ { "name": "SNIP1", "type": "recommended", "evidence": [ { "id": "E1BNB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB3" } ] } ], "protein_names": [ { "name": "Smad nuclear interacting protein 1", "type": "synonym", "evidence": [ { "id": "E1BNB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.", "evidence": [ { "database": "UniProtKB", "id": "E1BNB3", "url": "https://www.uniprot.org/uniprotkb/E1BNB3#function" }, { "database": "UniProtKB", "id": "ARBA00055964", "url": "https://www.uniprot.org/uniprotkb/ARBA00055964#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNB3", "url": "https://www.uniprot.org/uniprotkb/E1BNB3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SNIP1", "url": "https://www.uniprot.org/uniprotkb/E1BNB3", "locus": { "chromosome": "3", "start_pos": 108355568, "end_pos": 108338982, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016852", "url": "https://www.ensembl.org/id/ENSBTAG00000016852" } ] } } ], "crossref": [ { "id": "E1BNB3", "url": "https://alphafold.ebi.ac.uk/entry/E1BNB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016852", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016852", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22718", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22718", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WQKSCWL", "url": "https://omabrowser.org/oma/group/WQKSCWL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNB3", "url": "https://www.orthodb.org/?gene=E1BNB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BNB3", "url": "https://www.uniprot.org/uniprotkb/E1BNB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNB3-1", "url": "https://www.uniprot.org/uniprotkb/E1BNB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEVKSERERGSRRRHRDGDMVGIAPAVVVKQERLSPESAPPVHRRPDSSGGSPSPPAGESGRPSHRGNRARGGSRSPAKKKNKSSGRRSKSPRSKRSRSPHHSAIKVKQEREDHPRRGREDRPHREPSGQEHKRARNSDRDRHRGHSHQRRSSGERPGSGQPQGRDRDAQNLQAQEAEREFHNTRRREHRQKNEVSAGSNASQDALPRPGPGGNNKDREVPVKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSEVDRKEDEDDEEEEEMLFGACFSSRLYRRTMAAASVC", "length": 417, "header": "tr|E1BNB3-1|E1BNB3_BOVIN Isoform 1 of Smad nuclear interacting protein 1 OS=Bos taurus OX=9913 GN=SNIP1 PE=4 SV=2 CANONICAL=E1BNB3-1" }, "isoforms": [ { "isoform_ac": "E1BNB3-1", "url": "https://www.uniprot.org/uniprotkb/E1BNB3/entry#E1BNB3-1", "sequence": { "sequence": "MKEVKSERERGSRRRHRDGDMVGIAPAVVVKQERLSPESAPPVHRRPDSSGGSPSPPAGESGRPSHRGNRARGGSRSPAKKKNKSSGRRSKSPRSKRSRSPHHSAIKVKQEREDHPRRGREDRPHREPSGQEHKRARNSDRDRHRGHSHQRRSSGERPGSGQPQGRDRDAQNLQAQEAEREFHNTRRREHRQKNEVSAGSNASQDALPRPGPGGNNKDREVPVKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSEVDRKEDEDDEEEEEMLFGACFSSRLYRRTMAAASVC", "length": 417, "header": "tr|E1BNB3-1|E1BNB3_BOVIN Isoform 1 of Smad nuclear interacting protein 1 OS=Bos taurus OX=9913 GN=SNIP1 PE=4 SV=2 CANONICAL=E1BNB3-1" }, "locus": { "chromosome": "3", "start_pos": 108355000, "end_pos": 108339181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022416.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022416.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022416.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022416.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LQU1-1", "protein_name": "Smad nuclear interacting protein 1", "gene_name": "SNIP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKEVKSERERGSRRRHRDGDMVAAATVVVKQERLSPESAPPVHRRPDSSGGSPSPLAGESGRPGHRGNRARGGSRSPPRKKNKSSGRRSKSPRSRRSRSPHHSTVKVKQEREDHPRRGREDRPHREPSGQEHKRARNSDRDRHRSHSHQRRGSNERPGGGQPQGRDRDIQNLQAQEAEREFYNARRREHRQKNEASAGNTSQDSLARPGGNNKDKEVPAKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSEVDRKEDEDDEEEEEVSDS", "length": 395 }, "evidence": [ { "id": "E1BNB3", "url": "https://omabrowser.org/oma/group/E1BNB3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5M9G6-1", "protein_name": "Smad nuclear interacting protein 1", "gene_name": "Snip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKAGKSERERSSRRRHRSGDALATVVVKQERLSPEPVAHRRPDAPAASPPPPAAESGSAGHRGSRARGASRSPAKKKSKSSGRRSKSPRTKRSRSPHYSTVKVKQEREDHPRRGREDRQHRELSEQEHRRARNSERDRHRGHARQRRSSDERPVSGQGRDRDSQILQAQEEERDFNNARRREHRQQNESAGAEAQEVIPRPAGNKNKEVPVKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSELDRKEDEDEEEEEEMVSDSS", "length": 389 }, "evidence": [ { "id": "E1BNB3", "url": "https://omabrowser.org/oma/group/E1BNB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BIZ6-1", "protein_name": "Smad nuclear-interacting protein 1", "gene_name": "Snip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKAGKSERERSGRRRHRSGDALTTVVVKQERLSPEPVAHRRPDAPAASLSPPAAEPGHSGHRGSRARSPAKKKSKSSGRRSKSPRTKRSQSPHYPMVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSERDRHRGHSRQGRSSDERPVSGQDRDRDSQNLQAQEEERDFHNARRREHRQQNESAGSEAQEVIPRPAGNRSKEVPVKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSELDRKEDEDDEEEEMVSDS", "length": 383 }, "evidence": [ { "id": "E1BNB3", "url": "https://omabrowser.org/oma/group/E1BNB3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TAD8-1", "protein_name": "Smad nuclear-interacting protein 1", "gene_name": "SNIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSEIDRKDDEDEEEEEEVSDS", "length": 396 }, "evidence": [ { "id": "E1BNB3", "url": "https://omabrowser.org/oma/group/E1BNB3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1BNB3", "url": "https://www.uniprot.org/uniprotkb/E1BNB3" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "E1BNB3", "url": "https://www.uniprot.org/uniprotkb/E1BNB3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BNB3", "url": "https://www.uniprot.org/uniprotkb/E1BNB3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BNB3", "url": "https://www.uniprot.org/uniprotkb/E1BNB3" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "E1BNB3", "url": "https://www.uniprot.org/uniprotkb/E1BNB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "E1BNB3", "url": "https://www.uniprot.org/uniprotkb/E1BNB3" } ], "pmid": "" }, { "name": "miRNA processing", "id": "GO:0035196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035196", "evidence": [ { "database": "UniProtKB", "id": "E1BNB3", "url": "https://www.uniprot.org/uniprotkb/E1BNB3" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "E1BNB3", "url": "https://www.uniprot.org/uniprotkb/E1BNB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB3" }, { "id": "PS50006", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50006" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHA", "eco_id": "ECO_0000259", "start_pos": 284, "end_pos": 347, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45168", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45168", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45168:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45168:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002697194", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697194", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BNC7", "url": "https://www.uniprot.org/uniprotkb/E1BNC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNC7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANYYEVLGVQASASPEDIKKAYRKLALRWHPDKNPDNKEEAEKKFKQVSEAYEVLSDSKKRSLYDRAGCDGWRLGGTGSPHGSPFGGGYTFRNPEDIFREFFGGLDPFSFDFWDAPFGSERGARGHGLRGAFSAGFGEFPAFMEAFSAFDSLGRGGAGRTTFSSTSFGGSGSGGSGFKSVMSSTEIVNGHKVTTKRIVENGQERVEVEEDGQLTSVTINGKEQLKRVDSK", "length": 231, "header": "tr|E1BNC7-1|E1BNC7_BOVIN Isoform 1 of DnaJ heat shock protein family (Hsp40) member B8 OS=Bos taurus OX=9913 GN=DNAJB8 PE=4 SV=2 CANONICAL=E1BNC7-1" }, "isoforms": [ { "isoform_ac": "E1BNC7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNC7/entry#E1BNC7-1", "sequence": { "sequence": "MANYYEVLGVQASASPEDIKKAYRKLALRWHPDKNPDNKEEAEKKFKQVSEAYEVLSDSKKRSLYDRAGCDGWRLGGTGSPHGSPFGGGYTFRNPEDIFREFFGGLDPFSFDFWDAPFGSERGARGHGLRGAFSAGFGEFPAFMEAFSAFDSLGRGGAGRTTFSSTSFGGSGSGGSGFKSVMSSTEIVNGHKVTTKRIVENGQERVEVEEDGQLTSVTINGKEQLKRVDSK", "length": 231, "header": "tr|E1BNC7-1|E1BNC7_BOVIN Isoform 1 of DnaJ heat shock protein family (Hsp40) member B8 OS=Bos taurus OX=9913 GN=DNAJB8 PE=4 SV=2 CANONICAL=E1BNC7-1" }, "locus": { "chromosome": "22", "start_pos": 59370890, "end_pos": 59370198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008122.6", "url": "https://www.ensembl.org/id/ENSBTAT00000008122.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008122.4", "url": "https://www.ensembl.org/id/ENSBTAP00000008122.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:518674", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518674", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TY98-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member B8", "gene_name": "DNAJB8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANYYEVLGVQASASPEDIKKAYRKLALRWHPDKNPDNKEEAEKKFKQVSEAYEVLSDSKKRSVYDRAGCDSWRAGGASTPYSSPFDSGYIFRNPEDIFREFFGGLDPFSFDFWDTPFVSDRGGRGHGLRGAFSAGFGEFPAFMEAFSAFDTLGRGVGGAGRTTFSSTSFSGSGSSGFKSVMSSTEMVNGHKVTTKRIVENGQERVEVEEDGQLKSVTINGKEQLKRVDSK", "length": 231 }, "evidence": [ { "id": "E1BNC7", "url": "https://omabrowser.org/oma/group/E1BNC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZWI8-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member B8", "gene_name": "Dnajb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANYYEVLGVQSSASPEDIKKAYRKLALRWHPDKNPDNKEEAEKKFKQVSEAYEVLSDSKKRSVYDRAGCDGWRAGGGASVPHAGPFGAGYPFRNPEDIFREFFGGLDPFSFEFWDTPFSDRGRPHGLRGAFSSGFGEFPAFMEAFSSFDTLGHGGGSHSTFSSTSFGGSGSGSSGFKSVMSSTEMVNGRKVTTKRIVENGHERVEVEEDGKLRSVTVNGKEKLMRVDSK", "length": 230 }, "evidence": [ { "id": "E1BNC7", "url": "https://omabrowser.org/oma/group/E1BNC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HIC8-1", "protein_name": "DnaJ homolog subfamily B member 8", "gene_name": "Dnajb8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MANYYEVLGVQSSASPEDIKKAYRKLALRWHPDKNPDNKEEAEKKFKQVSEAYEVLSDSKKRSLYDRAGCDSWRAGGGGNVPHGSPFGAGYPFRNPEDIFREFFGGMDPFSFDFWDTPFSDRGRTHGTRGAFSSGFGEFPAFMEAFSSFDALGRGGGSRTTFSTTSMGGSSSGNSGFKSVISSTEIVNGHKVTTKRIVENGQERVEVEEDGKLRSVTVNGKEKIMRVDNK", "length": 230 }, "evidence": [ { "id": "E1BNC7", "url": "https://omabrowser.org/oma/group/E1BNC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8NHS0-1", "protein_name": "DnaJ homolog subfamily B member 8", "gene_name": "DNAJB8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANYYEVLGVQASASPEDIKKAYRKLALRWHPDKNPDNKEEAEKKFKLVSEAYEVLSDSKKRSLYDRAGCDSWRAGGGASTPYHSPFDTGYTFRNPEDIFREFFGGLDPFSFEFWDSPFNSDRGGRGHGLRGAFSAGFGEFPAFMEAFSSFNMLGCSGGSHTTFSSTSFGGSSSGSSGFKSVMSSTEMINGHKVTTKRIVENGQERVEVEEDGQLKSVTVNGKEQLKWMDSK", "length": 232 }, "evidence": [ { "id": "E1BNC7", "url": "https://omabrowser.org/oma/group/E1BNC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYI7-1", "protein_name": "DnaJ homolog subfamily B member 8", "gene_name": "Dnajb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANYYEVLGVQSSASPEDIKKAYRKLALRWHPDKNPDNKEEAEKKFKQVSEAYEVLSDSKKRSVYDRAGCDRWRAGGGANVPHSSPFGAGYPFRNPEDIFREFFGGLDPFSFEFWDTPFSGRGRPHGLHRVFPSGFGEFPAFMEALSSFNTLGHGGGSRSTFSSASFGGSGSSGFKSVMSSTEMVNGRKVTTKRIIENGQERVEVEEDGQLRSVTVNGKEKLMRVDK", "length": 227 }, "evidence": [ { "id": "E1BNC7", "url": "https://omabrowser.org/oma/group/E1BNC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of inclusion body assembly", "id": "GO:0090084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090084", "evidence": [ { "database": "UniProtKB", "id": "E1BNC7", "url": "https://www.uniprot.org/uniprotkb/E1BNC7" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "E1BNC7", "url": "https://www.uniprot.org/uniprotkb/E1BNC7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BNC7", "url": "https://www.uniprot.org/uniprotkb/E1BNC7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BNC7", "url": "https://www.uniprot.org/uniprotkb/E1BNC7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BNC7", "url": "https://www.uniprot.org/uniprotkb/E1BNC7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "E1BNC7", "url": "https://www.uniprot.org/uniprotkb/E1BNC7" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "E1BNC7", "url": "https://www.uniprot.org/uniprotkb/E1BNC7" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "E1BNC7", "url": "https://www.uniprot.org/uniprotkb/E1BNC7" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "E1BNC7", "url": "https://www.uniprot.org/uniprotkb/E1BNC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNC7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 231, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNC7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNC7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNC7" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 69, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNE3-1", "uniprot_ac": "E1BNE3", "uniprot_id": "E1BNE3_BOVIN", "mass": { "chemical_mass": 35273.0, "monoisotopic_mass": 35273.0 }, "refseq": { "ac": "NP_001377147", "name": "olfactory receptor 5A1", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377147" }, "gene_names": [ { "name": "OR5A1", "type": "recommended", "evidence": [ { "id": "E1BNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE3" } ] }, { "name": "OR5A1", "type": "synonym", "evidence": [ { "id": "NP_001377147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377147" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5A1", "type": "synonym", "evidence": [ { "id": "NP_001377147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377147" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377147", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377147" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BNE3", "url": "https://www.uniprot.org/uniprotkb/E1BNE3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNE3", "url": "https://www.uniprot.org/uniprotkb/E1BNE3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5A1", "url": "https://www.uniprot.org/uniprotkb/E1BNE3", "locus": { "chromosome": "15", "start_pos": 82655135, "end_pos": 82654179, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000027490", "url": "https://www.ensembl.org/id/ENSBTAG00000027490" } ] } } ], "crossref": [ { "id": "E1BNE3", "url": "https://alphafold.ebi.ac.uk/entry/E1BNE3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15417", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15417", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "615987", "url": "https://www.ncbi.nlm.nih.gov/gene/615987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"id": "IPR016449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BNF2", "url": "https://www.orthodb.org/?gene=E1BNF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01007", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01007", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNG6-1", "uniprot_ac": "E1BNG6", "uniprot_id": "E1BNG6_BOVIN", "mass": { "chemical_mass": 87959.0, "monoisotopic_mass": 87959.0 }, "refseq": { "ac": "XP_024836680", "name": "protein FAM171A2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836680" }, "gene_names": [ { "name": "FAM171A2", "type": "recommended", "evidence": [ { "id": "E1BNG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG6" } ] }, { "name": "FAM171A2", "type": "synonym", "evidence": [ { "id": "XP_024836680", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836680" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 171 member A2", "type": "synonym", "evidence": [ { "id": "E1BNG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG6/entry#names_and_taxonomy" } ] }, { "name": "protein FAM171A2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024836680", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836680" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNG6", "url": "https://www.uniprot.org/uniprotkb/E1BNG6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM171A2", "url": "https://www.uniprot.org/uniprotkb/E1BNG6", "locus": { "chromosome": "19", "start_pos": 44156316, "end_pos": 44167155, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011447", "url": "https://www.ensembl.org/id/ENSBTAG00000011447" } ] } } ], "crossref": [ { "id": "E1BNG6", "url": "https://alphafold.ebi.ac.uk/entry/E1BNG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011447", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011447", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "615144", "url": "https://www.ncbi.nlm.nih.gov/gene/615144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048530", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048530", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:615144", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615144", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLICAGP", "url": "https://omabrowser.org/oma/group/HLICAGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNG6", "url": "https://www.orthodb.org/?gene=E1BNG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31626", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31626", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31626:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31626:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024836680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836680", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BNG6", "url": "https://www.uniprot.org/uniprotkb/E1BNG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNG6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNG6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPPSGPSVLARLLPLLGLLLGGASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRMLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARSQPWVQFQRRAARLPVTSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSGNGSWLELMPVAAVSVHLLAGNGTEVPLSGPIHLSLPVPSEPRALAVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWAAAMASPTAGLVTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLVYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQATSMSQLHLICGGSLEPAPSGDPEAPPPGPLHSAFSSSRDLTGSRDDFFRAKPRSASRPAAEPTGARGGEGAGLKGARSVEGPAGLEPGLEEYRRGPPGTPAFLQEPPSPPPPFEHYLGHKGAAESKTPDFLLSQSVDQLARPPSLSQAGQLIFCGSIDHLKDSVYRNVMPTLVIPAHYVRLGGEAGATGAGEESAPPEGAAPGPARPFPQPDPQRPLMPGHSGAGGEGGGGGGGEGWGSGRSAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGGGGRSTDASLDSGVDVHEARPARRRPLREERERAPATAPPAPPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVAAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK", "length": 831, "header": "tr|E1BNG6-1|E1BNG6_BOVIN Isoform 1 of Family with sequence similarity 171 member A2 OS=Bos taurus OX=9913 GN=FAM171A2 PE=3 SV=3 CANONICAL=E1BNG6-1" }, "isoforms": [ { "isoform_ac": "E1BNG6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNG6/entry#E1BNG6-1", "sequence": { "sequence": "MPPPSGPSVLARLLPLLGLLLGGASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRMLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARSQPWVQFQRRAARLPVTSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSGNGSWLELMPVAAVSVHLLAGNGTEVPLSGPIHLSLPVPSEPRALAVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWAAAMASPTAGLVTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLVYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQATSMSQLHLICGGSLEPAPSGDPEAPPPGPLHSAFSSSRDLTGSRDDFFRAKPRSASRPAAEPTGARGGEGAGLKGARSVEGPAGLEPGLEEYRRGPPGTPAFLQEPPSPPPPFEHYLGHKGAAESKTPDFLLSQSVDQLARPPSLSQAGQLIFCGSIDHLKDSVYRNVMPTLVIPAHYVRLGGEAGATGAGEESAPPEGAAPGPARPFPQPDPQRPLMPGHSGAGGEGGGGGGGEGWGSGRSAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGGGGRSTDASLDSGVDVHEARPARRRPLREERERAPATAPPAPPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVAAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK", "length": 831, "header": "tr|E1BNG6-1|E1BNG6_BOVIN Isoform 1 of Family with sequence similarity 171 member A2 OS=Bos taurus OX=9913 GN=FAM171A2 PE=3 SV=3 CANONICAL=E1BNG6-1" }, "locus": { "chromosome": "19", "start_pos": 44166894, "end_pos": 44156846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061535.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061535.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053534.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053534.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 431, "start_aa": "Thr", "end_pos": 431, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr431", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 467, "start_aa": "Thr", "end_pos": 467, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr467", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:615144", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615144", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2A699-1", "protein_name": "Protein FAM171A2", "gene_name": "Fam171a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPPSGPGVLARLLPLLGLLLGGASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARSQPWVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSGNGSWLELIPLAAVSVHLLTGNGTEVPLSGPIHLSLPVPSEPRALAVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTSGLVTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDNKRDQATSMSQLHLICGGPLEPTSSGDPEAPPPGSLHSAFSSSRDLASSRDDFFRAKPRSASRPAAEPPGARTVEGAGLKSARSVEGPGGLEPSLDEYRRGPAGAAAFLHEPPSPPPSFDHYLGHKGAAESKTPDFLLSQSVDQLARPPSLSQPGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDEATPPEGSAAGPARPFPQPDPQRPLMQGHAGAGGDSGGGEGWGGGRSAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGSGGRSTDASLDSGVDVHEARPARRRLPREERERAQLPAPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVVAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK", "length": 822 }, "evidence": [ { "id": "E1BNG6", "url": "https://omabrowser.org/oma/group/E1BNG6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A8MVW0-1", "protein_name": "Protein FAM171A2", "gene_name": "FAM171A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPASGPSVLARLLPLLGLLLGSASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARSQPLVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSGNGSWLELMPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSETRALTVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTAGLVTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQATSMSQLHLICGGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARRRPAREERERAPPAAPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVAAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK", "length": 826 }, "evidence": [ { "id": "E1BNG6", "url": "https://omabrowser.org/oma/group/E1BNG6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZT47-1", "protein_name": "Family with sequence similarity 171, member A2", "gene_name": "Fam171a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPPSGPGVLARLLPLLGLLLGGASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARSQPWVQFQRRAARLPVSSTYNQLWASLTPASTQQEMRAFPAFLGTEASSSGNGSWLELIPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSEPRALAVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTSGLVTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDNKRDQATSMSQLHLICGGPLEPTSSGDPEAPPPGSLHSAFSSSRDLASSRDDFFRAKPRSASRPAAEPPGARSVEGAGLKGARSVEGPGVLEPSLEEYRRGPAGAAAFLHEAPSPPPSFDHYLGHKGAAESKTPDFLLSQSVDQLARPPSLSQPGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDEATPPEGSAAGPARPFPQPDPQRPLIQGHAGAGGDGGGGEGWGGGRSAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGGGGRSTDASLDSGVDVHEARPARRRPPREERERAQPPAPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVVAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK", "length": 822 }, "evidence": [ { "id": "E1BNG6", "url": "https://omabrowser.org/oma/group/E1BNG6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F078-1", "protein_name": "Protein FAM171A2", "gene_name": "fam171a2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRPQRASRFFALFLFLCSAWRSLAKSLPSPGPVEVLIKVQVFDNSDLSPLRESTVQVCGNQTILASNLVGEDGIVTLTFLYRPGTWVIVTASKHGFVTNSAPWHASRVPLYASVSLYLLPQRPATLLLYDDVVQLLLGSPGSRRQPWVQLQRRAIQPPLNNSQITLSAMLTSSRSQYELGGFPYPLAMDNNSTGTNSSWVELTALAAMCAQLTGPNGTEVQVSEPIHISIPLPSDSPLKTATSVPVWRFEDKTGLWVRSGAGYIKKEDTQMTWSFVAPKLGYWLAAFPSTSGSGLNTSGLRDITTYHTIFLLAILGAMALLVLILLCLLLYYCRRRCLKPRQHRRKMHLSSTLESSKRDQGTSTSHLNLISGGHMETASSTGDLNSSRDDFFKHGPTQRQHNSRTNADSKRGESFPLKATRSSNTGTRDLLLQDDYGKGYSSAEDSDDRKYNHHNAKDNQGYSSDPPSPPPLLPPFAGHYQDLNRDSKPPEYYASAGDHLNRPSSVNTQPGQLIFCHSMEQMKESMYHSMVPTLVIPAHYMHLSSDLTAVEQAMERQQQLQHDMEGIQVSMTLPRQQNQKQQQQQARADNEEEESGKQADGSSEENWGSDQSSAPVRIPVLFNDSTIAQMNGELQAMTEKKLLELGVKPHPRAWFVSLDGRSNSLVRHSYIELSNEALRPPMGACNQTLDQRTEAIPTNSGKPSHRKLKEDGKVKEGGERKAHGKIYSKLPVIETPDSSSESHSAMYSPEENSTAPLLDETAEVSKGGTFPRKGRSRDNSTRSSASEVHRDSVTSPDDDNDDKDDDGENKKSPWQKREERPLMVFNVK", "length": 828 }, "evidence": [ { "id": "E1BNG6", "url": "https://omabrowser.org/oma/group/E1BNG6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RQY9-1", "protein_name": "Family with sequence similarity 171 member A2", "gene_name": "FAM171A2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPPSGPSVLARLLPLLGLLLGGASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRMLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARSQPWVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTDASSSGNGSWLELMPVAAVSVHLLAGNGTEVPLSGPIHLSLPVPSEPRALAVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFISPQLGYWAAAMASPTSGLVTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQATSMSQLHLICGGPLEPATSGDPEAPPPGPLHSAFSSSRDLAASRDDFFRAKPRSASRPAAEPAGARGGEGAGLKGARSVEGPGGLEPGLEEYRRGAPGTATFLQEPPSPPPPFEHYLGHKGAAESKTPDFLLSQSVDQLARPPSLSQAGQLIFCGSIDHLKDSVYRNVMPTLVIPAHYVRLGGEAGATGAGDEPAPPEGAAPGPARPFPQPDPQRPLMPGHPSAGGEGGGGGGGEGWGGGRSAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGGGGRSTDASLDSGVDVHEARPARRRPLREERERAAAAAPPPPPPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVAAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK", "length": 832 }, "evidence": [ { "id": "E1BNG6", "url": "https://omabrowser.org/oma/group/E1BNG6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BNG6", "url": "https://www.uniprot.org/uniprotkb/E1BNG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNG6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 831, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNG6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNG6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG6" }, { "id": "PF20771", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20771" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM171 C-terminal", "eco_id": "ECO_0000259", "start_pos": 382, "end_pos": 829, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG6" }, { "id": "PF10577", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10577" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM171 N-terminal", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 295, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 431, 467 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 624, "end_pos": 626 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNG7-1", "uniprot_ac": "E1BNG7", "uniprot_id": "E1BNG7_BOVIN", "mass": { "chemical_mass": 103008.0, "monoisotopic_mass": 103008.0 }, "refseq": {}, "gene_names": [ { "name": "TUBGCP3", "type": "recommended", "evidence": [ { "id": "E1BNG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ] } ], "protein_names": [ { "name": "Tubulin gamma complex component 3", "type": "synonym", "evidence": [ { "id": "E1BNG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TUBGCP3", "url": "https://www.uniprot.org/uniprotkb/E1BNG7", "locus": { "chromosome": "12", "start_pos": 86186310, "end_pos": 86222088, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000044184", "url": "https://www.ensembl.org/id/ENSBTAG00000044184" } ] } } ], "crossref": [ { "id": "E1BNG7", "url": "https://alphafold.ebi.ac.uk/entry/E1BNG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000044184", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044184", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MRMMSVC", "url": "https://omabrowser.org/oma/group/MRMMSVC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNG7", "url": "https://www.orthodb.org/?gene=E1BNG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19302:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19302:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNG7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATPDQKSPNVLLQSLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKKELTRQRREADAALFSELHRKLHSQGVLKNKWSVLYLLLSLSEDPRRQPGKVSNYATLFAQALPRDAHSTPYYYARPQTLPLNYQERSAPSAQSSGSLGSSGISSIGVHTNGPTPPPPSLLPGQSHLGPGTGDCLRQQLGARLAWTLPASQPSLQTTTSKGVPSAASRSMTRPRRDGDAGGAVEVTEAALVRDILYVFQGIDGRNIKMSSADNCYKVEGKANLNKSLRDTAMRLAELGWLHNKIRKYTDQRSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVNLGFESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPSMRSLVQHILSLVSHPVLSFLYRWIYDGELEDTHHEFFVASDPTVKTDRLWHDKYTLRTSMIPSFMTMDQSRKVLLIGKSINFLHQVCHDQTPPTKMIAVPRSAEPLQDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNRKYSLLDHMQAVRRYLLLGQGDFIRHLMDLLKPELARPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRSLPEFSGVLHHCHILASEMVHFIHQMQYYITFEVLECSWDELWNQVQQAQDLDHIIAAHEAFLGTVISRCLLDSDSRALLNQLRAVFDQIIELQSTQDAICRAALEELQRRLQFEDKKKQREAEGQWGVTAAEEEQENQRIREFRESIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLRFLSFRLDFNEHYRAREPRLRVSLGARGRRSSHT", "length": 906, "header": "tr|E1BNG7-1|E1BNG7_BOVIN Isoform 1 of Tubulin gamma complex component 3 OS=Bos taurus OX=9913 GN=TUBGCP3 PE=3 SV=2 CANONICAL=E1BNG7-1" }, "isoforms": [ { "isoform_ac": "E1BNG7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNG7/entry#E1BNG7-1", "sequence": { "sequence": "MATPDQKSPNVLLQSLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKKELTRQRREADAALFSELHRKLHSQGVLKNKWSVLYLLLSLSEDPRRQPGKVSNYATLFAQALPRDAHSTPYYYARPQTLPLNYQERSAPSAQSSGSLGSSGISSIGVHTNGPTPPPPSLLPGQSHLGPGTGDCLRQQLGARLAWTLPASQPSLQTTTSKGVPSAASRSMTRPRRDGDAGGAVEVTEAALVRDILYVFQGIDGRNIKMSSADNCYKVEGKANLNKSLRDTAMRLAELGWLHNKIRKYTDQRSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVNLGFESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPSMRSLVQHILSLVSHPVLSFLYRWIYDGELEDTHHEFFVASDPTVKTDRLWHDKYTLRTSMIPSFMTMDQSRKVLLIGKSINFLHQVCHDQTPPTKMIAVPRSAEPLQDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNRKYSLLDHMQAVRRYLLLGQGDFIRHLMDLLKPELARPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRSLPEFSGVLHHCHILASEMVHFIHQMQYYITFEVLECSWDELWNQVQQAQDLDHIIAAHEAFLGTVISRCLLDSDSRALLNQLRAVFDQIIELQSTQDAICRAALEELQRRLQFEDKKKQREAEGQWGVTAAEEEQENQRIREFRESIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLRFLSFRLDFNEHYRAREPRLRVSLGARGRRSSHT", "length": 906, "header": "tr|E1BNG7-1|E1BNG7_BOVIN Isoform 1 of Tubulin gamma complex component 3 OS=Bos taurus OX=9913 GN=TUBGCP3 PE=3 SV=2 CANONICAL=E1BNG7-1" }, "locus": { "chromosome": "12", "start_pos": 86221999, "end_pos": 86187159, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061427.3", "url": "https://www.ensembl.org/id/ENSBTAT00000061427.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053533.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053533.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 173, "start_aa": "Thr", "end_pos": 173, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr173", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-BTA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUU7-1", "protein_name": "Tubulin gamma complex component 3", "gene_name": "Tubgcp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQFAVRVIGSNFAPTVERDEFLVAEKIKKELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLNLSEDPRKQASKVTSYASLFAQALPRDAHSTPYYCARPQTLPLNYQDRSTQSSGSLGSSGISSIGMCGLSGPTPVQPFLPGQSHQAPGVGDGLRQQLGPRLAWTLTGNQPSQTPTSKAFPNALSRNLTRSRREGDPGGTSEVTEAALVRDILYVFQGIDGKNIKMSSTENCYKVEAKANLSKSLRDTAVRLAELGWLHNKIRKYADQRSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVNVGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMKSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFITMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPRDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNRKYSLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNRVQQAQDLDHIIAAHEAFLDTITSRCLLDSNSRVLLNQLRAVFDQIIELQNAQDTMYRAALEELQRRLQFEEKKKQRETEGQWGVTAAEEEEENKRIREFQDSIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLQFLSFRLDFNEHYKAREPRLRVSLGSRGRRSSHT", "length": 902 }, "evidence": [ { "id": "E1BNG7", "url": "https://omabrowser.org/oma/group/E1BNG7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QA15-1", "protein_name": "Gamma-tubulin complex component 3 isoform X1", "gene_name": "tubgcp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATLDQKSPNVLLQSLCCKITGKSEADVAHQFQYAVRVIGSNYAPTIERDEFLVSEKIKKELLKQRREADAALFSELHRKLQTQGVLKHRWSILYLLLSLCEDPRKPSGRVPVCSYGALLAQALPRDVHSTPFYYARPQSLPLSYPERSATAHNSSMATSGISSMGVFSINGPGPTPPSLLTGAGTQAVGESMRGSRLAWTLPVSSSPSGAAAAPRPPSGPSSSPAPKPLQRPRRDGDGSADIGEAALVRDILYVFQGIDGKFIKMCSPENCYKIDSKVPLCKSLRDTSSRLAELGWLHNKIRKYTDSHSLDRAFGLVGQSFCAALHQELKEYYRLLSVLHAQLQVEDDQGVNMSVDSSLTLRRLLVWTYDPKVRLKTLAALVDYCQGRKGGELATAVHAYGKTGDPNMRALIQHILGLVSHPILNFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYSLRKSMIPSFITMDQARKVLLIGKSINFLHQVCHDRTPPGKIMPASKSKDSPKDAAELFTDLEGTFQSKIDAAYFETSKYLLDVLNKNYQLLEHLQAMRRYLLLGQGDFIRHLMDLLKPELARPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVEGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIWKGQMCNAKLLKSMPELSGVLHQCHVLASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHDVFLDTIISRCLLDVNNRSLLNQLRAVFDQIIEFQNAQDTLYRSALEELQLRIQFEDKKRQREEMAEWGVTAEQEAEENRRVQEFKDTIPKMCSQLRLLTHFYQGIVQEFLRLLMTCSDESLQFLSFRLDFNEHYKARDPRLRPSLGATRGRRSSNI", "length": 906 }, "evidence": [ { "id": "E1BNG7", "url": "https://omabrowser.org/oma/group/E1BNG7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RN46-1", "protein_name": "Tubulin gamma complex component 3", "gene_name": "TUBGCP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATPDQKSPNVLLQNLCCRILGKSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKKELTRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRKQPSKVSGYAALFAQALPRDAHSTPYYYARPQSLPLNYQERGAPSAQSAGSAGSSGVSSLGTYALNGPTPPPPPPALLPGQPLPAPGVGDGLRQQLGSRLAWTLTASQPSLPSTTSKAVPSSGSRGAARPRREGDAAAGAVEVTEAALVRDILYVFQGIDGKHVKMSNADNCYTVEGKANLSKSLRDTAVRLAELGWLHNKIRKYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVNLGLESSLTLRRLLVWTYDPKMRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYARSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPAVKADRLWHDKYALRKPMIPSFMTMDQCRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRAFNFLWRAKRVEYILTDIRKGHMCNARLLRSMPEFSGVLHHCHILASEMVHFIHQMQYYVTFEVLECSWDELWNRVQRAQDLDHIIAAHEAFLGTVISRCLLDSDSRALLNQLRAVFDQIIELQNTQDAIYRAALEELQRRLQFEEKKKQREAEGQWGVSAAEEEQEKRRVQEFQESIPKMCSQLRILTHFYQGVVQQFLVSLTTSSDESLRFLSFRLDFNEHYRAREPRLRVSLGTRGRRSSHT", "length": 910 }, "evidence": [ { "id": "E1BNG7", "url": "https://omabrowser.org/oma/group/E1BNG7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P58854-1", "protein_name": "Gamma-tubulin complex component 3", "gene_name": "Tubgcp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQFAVRVIGSNFAPTVERDEFLVAEKIKKELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLNLSEDPRKQASKVTSYASLFAQALPRDAHSTPYYYARPQTLPLNYQDRSTQAQSSGSLGSSGISSIGMCGLSGPTPVQPFLPGQSHQAPGVGDGLRQQLGPRLAWTLTGNQPSSQTPTSKGFPNALSRNLTRSRREGDPGGTLEVTEAALVRDILYVFQGIDGKNIKMSSTENCYKVEAKANLNKSLRDTAVRLAELGWLHNKIRKYADQRSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVNLGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMKSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFITMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPRDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNRVQQAQDLDHIIAAHEAFLNTITSRCLLDSNSRVLLNQLRAVFDQIIELQNAQDVMYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIREFQDSIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLQFLSFRLDFNEHYKAREPRLRVSLGSRGRRSSHT", "length": 905 }, "evidence": [ { "id": "E1BNG7", "url": "https://omabrowser.org/oma/group/E1BNG7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96CW5-1", "protein_name": "Gamma-tubulin complex component 3", "gene_name": "TUBGCP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKKELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRRQPSKVSSYATLFAQALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQSLLPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVSRNMTRSRREGDTGGTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKANLSRSLRDTAVRLSELGWLHNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVNLGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFMTMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFDQIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESIPKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTRGRRSSHT", "length": 907 }, "evidence": [ { "id": "E1BNG7", "url": "https://omabrowser.org/oma/group/E1BNG7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FG37-1", "protein_name": "Gamma-tubulin complex component 3", "gene_name": "GCP3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEDDDQQKAADLVQELVLRLVSQNPQTPNLDPNSPAFLKTLRYAFRILSSRLTPSVLPDATAIAESLKRRLATQGKSSDALAFADLYTKFASKTGPGSVNNKWALVYLLKIVSDDRKSAINGLDSSVLLPNLGIGDTGNGVLSRGEAKKKDWSNGVLLVSKDPENLRDIAFREYAILVKEENEVTEEVLVRDVLYASQGIDGKYVKFNSEIDGYAVQESVKVPRATRIMVRMLSELGWLFRKVKTFITESMDRFPAEDVGTVGQAFCAALQDELSDYYKLLAVLEAQAMNPIPLVSESASSNNYLSLRRLSVWFAEPMVKMRLMAVLVDKCKVLRGGAMAGAIHLHAQHGDPLVHDFMMSLLRCVCSPLFEMVRSWVLEGELEDTFGEFFVVGQPVKVDLLWREGYKLHPAMLPSFISPSLAQRILRTGKSINFLRVCCDDHGWADAASEAAAASGTTTRRGGLGYGETDALEHLVTEAAKRIDKHLLDVLYKRYKFKEHCLAIKRYLLLGQGDFVQYLMDIVGPKLSEPANNISSFELAGFLEAAIRASNAQYDDRDMLDRLRVKMMPHGSGDRGWDVFSLEYEARVPLDTVFTESVLSKYLRVFNFLWKLKRVEHALIGIWKTMKPNCITSNSFVKLQSSVKLQLLSALRRCQVLWNEMNHFVTNFQYYIMFEVLEVSWSNFSKEMEAAKDLDDLLAAHEKYLNAIVGKSLLGEQSQTIRESLFVLFELILRFRSHADRLYEGIHELQIRSKESGREKNKSQEPGSWISEGRKGLTQRAGEFLQSMSQDMDSIAKEYTSSLDGFLSLLPLQQSVDLKFLFFRLDFTEFYSRLHSKG", "length": 838 }, "evidence": [ { "id": "E1BNG7", "url": "https://omabrowser.org/oma/group/E1BNG7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "pmid": "" }, { "name": "polar microtubule", "id": "GO:0005827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005827", "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "pmid": "" }, { "name": "gamma-tubulin complex", "id": "GO:0000930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000930", "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "E1BNG7", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNG7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 906, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNG7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNG7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" }, { "id": "PF04130", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04130" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gamma tubulin complex component C-terminal", "eco_id": "ECO_0000259", "start_pos": 554, "end_pos": 885, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG7" }, { "id": "PF17681", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17681" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gamma tubulin complex component protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 250, "end_pos": 551, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 173 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 283, "end_pos": 285 }, { "start_pos": 595, "end_pos": 597 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNJ7-1", "uniprot_ac": "E1BNJ7", "uniprot_id": "E1BNJ7_BOVIN", "mass": { "chemical_mass": 44721.0, "monoisotopic_mass": 44721.0 }, "refseq": { "ac": "NP_001179477", "name": "heparan sulfate glucosamine 3-O-sulfotransferase 3A1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179477" }, "gene_names": [ { "name": "HS3ST3A1", "type": "recommended", "evidence": [ { "id": "E1BNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7" } ] }, { "name": "HS3ST3A1", "type": "synonym", "evidence": [ { "id": "NP_001179477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179477" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "E1BNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "E1BNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7/entry#names_and_taxonomy" } ] }, { "name": "heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1", "type": "synonym", "evidence": [ { "id": "NP_001179477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179477" } ] }, { "name": "heparan sulfate glucosamine 3-O-sulfotransferase 3A1", "type": "synonym", "evidence": [ { "id": "NP_001179477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179477" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNJ7", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HS3ST3A1", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7", "locus": { "chromosome": "19", "start_pos": 31737491, "end_pos": 31822568, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000031107", "url": "https://www.ensembl.org/id/ENSBTAG00000031107" } ] } } ], "crossref": [ { "id": "E1BNJ7", "url": "https://alphafold.ebi.ac.uk/entry/E1BNJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000031107", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000031107", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "521959", "url": "https://www.ncbi.nlm.nih.gov/gene/521959", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521959", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521959", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FYCLVER", "url": "https://omabrowser.org/oma/group/FYCLVER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNJ7", "url": "https://www.orthodb.org/?gene=E1BNJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605:SF64", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605:SF64", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022928", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179477", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179477", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BNJ7", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNJ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPGPAGAHPTSAEPLSRSVFRKFLLMLCSLLTSLYVFYCLAERCQTLSGPVVGRSGGGEEAGTPGRGVPAGGPGELAAWPVAARRKRLLQVRPRPRRRPPAPRADREEAGEEEPPGLAGSLGGSGAGSSVAETPPGTLALLLDEGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLLVVVRDPVTRAVSDYTQTLSKRPDIPSFESLAFRNRSAGLVDRSWSAIQIGLYAEHLERWLRHFPARQMLFVSGERLVRDPAGELGRVQDFLGLKRIISDKHFYFNQTKGFPCLKKAEGSGRPHCLGKTKGRPHPEIDAQVLRQLRDFYRPFNRKFYQMTGHDFGWDG", "length": 405, "header": "tr|E1BNJ7-1|E1BNJ7_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=HS3ST3A1 PE=3 SV=3 CANONICAL=E1BNJ7-1" }, "isoforms": [ { "isoform_ac": "E1BNJ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7/entry#E1BNJ7-1", "sequence": { "sequence": "MAPPGPAGAHPTSAEPLSRSVFRKFLLMLCSLLTSLYVFYCLAERCQTLSGPVVGRSGGGEEAGTPGRGVPAGGPGELAAWPVAARRKRLLQVRPRPRRRPPAPRADREEAGEEEPPGLAGSLGGSGAGSSVAETPPGTLALLLDEGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLLVVVRDPVTRAVSDYTQTLSKRPDIPSFESLAFRNRSAGLVDRSWSAIQIGLYAEHLERWLRHFPARQMLFVSGERLVRDPAGELGRVQDFLGLKRIISDKHFYFNQTKGFPCLKKAEGSGRPHCLGKTKGRPHPEIDAQVLRQLRDFYRPFNRKFYQMTGHDFGWDG", "length": 405, "header": "tr|E1BNJ7-1|E1BNJ7_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=HS3ST3A1 PE=3 SV=3 CANONICAL=E1BNJ7-1" }, "locus": { "chromosome": "19", "start_pos": 31822369, "end_pos": 31738495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044024.4", "url": "https://www.ensembl.org/id/ENSBTAT00000044024.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041543.3", "url": "https://www.ensembl.org/id/ENSBTAP00000041543.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:521959", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521959", "resource": "KEGG Pathway" }, { "id": "R-BTA-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZTA9-1", "protein_name": "Sulfotransferase", "gene_name": "Hs3st3b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQRLSGGRSCLDVPGRFLPQPPPPPPPVRRKLALLFAMLCIWLYMFLYSCAGSCTAAPGLLLLGSGSRATHAQPALITAPNETSPKMPFRAPPANSLVAGKDKTVGAGSQEEQSPEAPDSPSPISSFFSGAGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYHKGLAWYRDLMPRTLEGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPSFESLTFRNRSAGLIDTSWSAIQIGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGLKRIITDKHFYFNQTKGFPCLKKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRDFYRPFNRKFYQMTGRDFGWD", "length": 390 }, "evidence": [ { "id": "E1BNJ7", "url": "https://omabrowser.org/oma/group/E1BNJ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NL56-1", "protein_name": "Sulfotransferase", "gene_name": "HS3ST3A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVSAAAAPAAEPLPRSIFKKFLVMLCSLLMSLYVFYCLADRCQTLPGPIIAAGAASEEEEGGGGGYLGGSAELPPWQAAAARRKRLLQRLKQRRRRQEAAPGPEVPAGDGGSRAGGSGGGGGGGSAAGTAGTLTLLLGEGSKRLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRNYERGLAWYRDLMPRTLEGQITMEKTPSYFVTKEAPARISSMAKGTKLIVVVRDPVTRAISDYTQTLSKKPDIPTFESLTFKNRTTGLIDTSWSAIQIGIYAKHLENWLLYFPIGQILFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSKPHCLGKTKGRTHPDIDQEVVQRLRDFYRPFNMKFYQMTGQDFGWD", "length": 398 }, "evidence": [ { "id": "E1BNJ7", "url": "https://omabrowser.org/oma/group/E1BNJ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9QZS6-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 3B1", "gene_name": "Hs3st3b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQRLSGGRSCLDVPGRFLPQPPPPPPPVRRKLALLFAMLCIWLYMFLYSCAGSCTAAPGLLLLGSGSRATHAQPALVTAPNETSPKMPFRAPPANSLAAGKDKTVGAGSQEEQSPEAPDSPSPISSFFSGAGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYHKGLAWYRDLMPRTLKGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPSFESLTFRNRSAGLIDTSWSAIQIGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGLKRIITDKHFYFNQTKGFPCLKKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRDFYRPFNRKFYQMTGRDFGWD", "length": 390 }, "evidence": [ { "id": "E1BNJ7", "url": "https://omabrowser.org/oma/group/E1BNJ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y663-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 3A1", "gene_name": "HS3ST3A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPPGPASALSTSAEPLSRSIFRKFLLMLCSLLTSLYVFYCLAERCQTLSGPVVGLSGGGEEAGAPGGGVLAGGPRELAVWPAAAQRKRLLQLPQWRRRRPPAPRDDGEEAAWEEESPGLSGGPGGSGAGSTVAEAPPGTLALLLDEGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTFESLTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYRPFNLKFYQMTGHDFGWDG", "length": 406 }, "evidence": [ { "id": "E1BNJ7", "url": "https://omabrowser.org/oma/group/E1BNJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ7", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "glycosaminoglycan biosynthetic process", "id": "GO:0006024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006024", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ7", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7" } ], "pmid": "" }, { "name": "branching involved in ureteric bud morphogenesis", "id": "GO:0001658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001658", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ7", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ7", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "[heparan sulfate]-glucosamine 3-sulfotransferase activity", "id": "GO:0008467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008467", "evidence": [ { "database": "UniProtKB", "id": "E1BNJ7", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-2076611", "name": "HS3ST2-6 sulfate GlcN at C3 in heparan sulfate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKQ1-1", "E1BNJ7-1", "E1BP03-1" ], "evidence": [ { "id": "R-BTA-2076611", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2076611" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BKQ1", "gene_name": "HS3ST2", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BKQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ1" } ] } ] }, { "uniprot_ac": "E1BNJ7", "gene_name": "HS3ST3A1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7" } ] } ] }, { "uniprot_ac": "E1BP03", "gene_name": "HS3ST3B1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BP03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP03" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNJ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 405, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNJ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNJ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 392, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 272, "end_pos": 274 }, { "start_pos": 343, "end_pos": 345 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNK0-1", "uniprot_ac": "E1BNK0", "uniprot_id": "E1BNK0_BOVIN", "mass": { "chemical_mass": 70839.0, "monoisotopic_mass": 70839.0 }, "refseq": { "ac": "XP_002692696", "name": "XK-related protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692696" }, "gene_names": [ { "name": "XKR4", "type": "recommended", "evidence": [ { "id": "E1BNK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNK0" } ] }, { "name": "XKR4", "type": "synonym", "evidence": [ { "id": "XP_002692696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692696" } ] } ], "protein_names": [ { "name": "XK-related protein", "type": "recommended", "evidence": [ { "id": "E1BNK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNK0/entry#names_and_taxonomy" } ] }, { "name": "XK-related protein 4", "type": "synonym", "evidence": [ { "id": "XP_002692696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692696" } ] } ], "function": [ { "annotation": "Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment.", "evidence": [ { "database": "UniProtKB", "id": "E1BNK0", "url": "https://www.uniprot.org/uniprotkb/E1BNK0#function" }, { "database": "UniProtKB", "id": "ARBA00045305", "url": "https://www.uniprot.org/uniprotkb/ARBA00045305#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNK0", "url": "https://www.uniprot.org/uniprotkb/E1BNK0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "XKR4", "url": "https://www.uniprot.org/uniprotkb/E1BNK0", "locus": { "chromosome": "14", "start_pos": 22953771, "end_pos": 22640470, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000044050", "url": "https://www.ensembl.org/id/ENSBTAG00000044050" } ] } } ], "crossref": [ { "id": "E1BNK0", "url": "https://alphafold.ebi.ac.uk/entry/E1BNK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000044050", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044050", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "517598", "url": "https://www.ncbi.nlm.nih.gov/gene/517598", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:517598", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517598", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQQPGAD", "url": "https://omabrowser.org/oma/group/CQQPGAD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNK0", "url": "https://www.orthodb.org/?gene=E1BNK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002692696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "38663", "url": "https://www.rhea-db.org/rhea/38663", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BNK0", "url": "https://www.uniprot.org/uniprotkb/E1BNK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNK0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAKSDGRLKMKKGSDVAFTPLQNSDHSGSVQGLAPGLPSGSGAEDEEAAGGACCPDGSRCCCCCCCAGSGGSGGGSGGSGGPGGGSGPGSAALCLRLGPEQRRYSLWDCLWILAAVAVYFADVGTDIWLAVDYYLRGQRWWFGLTLFFVVLGSLSVQVFSFRWFVHDFSTEDSAAAAAGCAQPGAEGKTAVGGGAAAAEGEARPSTPQRQASSAGKGHVAATNSGSNSSGAARAGGKPRSASCSFCIWLLQSLTHILQLGQFWRYFHTIYLGIRSRQSGENDRWRFYWKMVYEYADVSMLHLLATFLESAPQLVLQLCIIVQTHSLQALQGFTAAASLVSLAWALASYQKALRDSRDDKKPISYMAVVIQFCWHFFTIAARVITFALFASVFQLYFGIFIVLHWCIMTFWIVHCETEFCITKWEEIVFDMVVGIIYIFSWFNVKEGRTRCRLFIYYFVILLENTALSALWYLYKAPQIADAFAIPALCVVFSSFLTGVVFMLMYYAFFHPNGPRFGQSPSCACEDPSAAFALPPDVATSTLRSISNNRSVAGDRDQKFAERDGCVPVFQVRPTAPSTPSSRPPRIEESVIKIDLFRNRYPAWERHVLDRSLRKAILAFECSPSPPRLQYKDDALIQERLEYETTL", "length": 646, "header": "tr|E1BNK0-1|E1BNK0_BOVIN Isoform 1 of XK-related protein OS=Bos taurus OX=9913 GN=XKR4 PE=3 SV=3 CANONICAL=E1BNK0-1" }, "isoforms": [ { "isoform_ac": "E1BNK0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNK0/entry#E1BNK0-1", "sequence": { "sequence": "MAAKSDGRLKMKKGSDVAFTPLQNSDHSGSVQGLAPGLPSGSGAEDEEAAGGACCPDGSRCCCCCCCAGSGGSGGGSGGSGGPGGGSGPGSAALCLRLGPEQRRYSLWDCLWILAAVAVYFADVGTDIWLAVDYYLRGQRWWFGLTLFFVVLGSLSVQVFSFRWFVHDFSTEDSAAAAAGCAQPGAEGKTAVGGGAAAAEGEARPSTPQRQASSAGKGHVAATNSGSNSSGAARAGGKPRSASCSFCIWLLQSLTHILQLGQFWRYFHTIYLGIRSRQSGENDRWRFYWKMVYEYADVSMLHLLATFLESAPQLVLQLCIIVQTHSLQALQGFTAAASLVSLAWALASYQKALRDSRDDKKPISYMAVVIQFCWHFFTIAARVITFALFASVFQLYFGIFIVLHWCIMTFWIVHCETEFCITKWEEIVFDMVVGIIYIFSWFNVKEGRTRCRLFIYYFVILLENTALSALWYLYKAPQIADAFAIPALCVVFSSFLTGVVFMLMYYAFFHPNGPRFGQSPSCACEDPSAAFALPPDVATSTLRSISNNRSVAGDRDQKFAERDGCVPVFQVRPTAPSTPSSRPPRIEESVIKIDLFRNRYPAWERHVLDRSLRKAILAFECSPSPPRLQYKDDALIQERLEYETTL", "length": 646, "header": "tr|E1BNK0-1|E1BNK0_BOVIN Isoform 1 of XK-related protein OS=Bos taurus OX=9913 GN=XKR4 PE=3 SV=3 CANONICAL=E1BNK0-1" }, "locus": { "chromosome": "14", "start_pos": 22953768, "end_pos": 22640470, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000060990.5", "url": "https://www.ensembl.org/id/ENSBTAT00000060990.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053508.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053508.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 578, "start_aa": "Thr", "end_pos": 578, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr578", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:517598", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517598", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5GH59-1", "protein_name": "XK-related protein 4", "gene_name": "Xkr4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARPPPLLVQKPSFLVEACCSPSPATHLAPYHTQPGARTPSTIQRDLLFPIPRRCHARSSPRPPALGGGPTQRLQHAARSAHPIPPSVKEIHPTFSEIPRARASDCCAAALGVQHWPARHPHPPLPSISLAVDYYLLGQRWWFGLTLFFVVLGSLSVQVFSFRWFVHDFSTEDSATTTASTCQQPGADCKTVVSSGSAAGEGEARPSTPQRQASNASKSNIAATNSGSNSNGATRTSGKHRSASCSFCIWLLQSLIHILQLGQVWRYLHTIYLGIRSRQSGESSRWRFYWKMVYEYADVSMLHLLATFLESAPQLVLQLCIIVQTHSLQALQGFTAAASLVSLAWALASYQKALRDSRDDKKPISYMAVIIQFCWHFFTIAARVITFALFASVFQLYFGIFIVLHWCIMTFWIVHCETEFCITKWEEIVFDMVVGIIYIFSWFNVKEGRTRCRLFIYYFVILLENTALSALWYLYKAPQIADAFAIPALCVVFSSFLTGVVFMLMYYAFFHPNGPRFGQSPSCACDDPATAFSMPPEVATSTLRSISNNRSVASDRDQKFAERDGCVPVFQVRPTAPPTPSSRPPRIEESVIKIDLFRNRYPAWERHVLDRSLRKAILAFECSPSPPRLQYKDDALIQERLEYETTL", "length": 647 }, "evidence": [ { "id": "E1BNK0", "url": "https://omabrowser.org/oma/group/E1BNK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5GH67-1", "protein_name": "XK-related protein 4", "gene_name": "Xkr4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAKSDGRLKMKKSSDVAFTPLQNSDNSGSVQGLAPGLPSGSGAEDTEAAGGGCCPDGGGCSRCCCCCAGSGGSAGSGGSGGGGRGSGAGSAALCLRLGREQRRYSLWDCLWILAAVAVYFADVGTDIWLAVDYYLRGQRWWFGLTLFFVVLGSLSVQVFSFRWFVHDFSTEDSSTTTTSSCQQPGADCKTVVSSGSAAGEGEVRPSTPQRQASNASKSNIAATNSGSNSNGATRTSGKHRSASCSFCIWLLQSLIHILQLGQIWRYLHTIYLGIRSRQSGESGRWRFYWKMVYEYADVSMLHLLATFLESAPQLVLQLCIIVQTHSLQALQGFTAAASLVSLAWALASYQKALRDSRDDKKPISYMAVIIQFCWHFFTIAARVITFALFASVFQLYFGIFIVLHWCIMTFWIVHCETEFCITKWEEIVFDMVVGIIYIFSWFNVKEGRTRCRLFIYYFVILLENTALSALWYLYKAPQIADAFAIPALCVVFSSFLTGVVFMLMYYAFFHPNGPRFGQSPSCACDDPATAFSLPPEVATSTLRSISNNRSVASDRDQKFAERDGCVPVFQVRPTAPPTPSSRPPRIEESVIKIDLFRNRYPAWERHVLDRSLRKAILAFECSPSPPRLQYKDDALIQERLEYETTL", "length": 647 }, "evidence": [ { "id": "E1BNK0", "url": "https://omabrowser.org/oma/group/E1BNK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5GH76-1", "protein_name": "XK-related protein 4", "gene_name": "XKR4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAKSDGRLKMKKSSDVAFTPLQNSDHSGSVQGLAPGLPSGSGAEDEEAAGGGCCPDGGGCSRCCCCCAGSGGSAGSGGSGGVAGPGGGGAGSAALCLRLGREQRRYSLWDCLWILAAVAVYFADVGTDVWLAVDYYLRGQRWWFGLTLFFVVLGSLSVQVFSFRWFVHDFSTEDSATAAAASSCPQPGADCKTVVGGGSAAGEGEARPSTPQRQASNASKSNIAAANSGSNSSGATRASGKHRSASCSFCIWLLQSLIHILQLGQIWRYFHTIYLGIRSRQSGENDRWRFYWKMVYEYADVSMLHLLATFLESAPQLVLQLCIIVQTHSLQALQGFTAAASLVSLAWALASYQKALRDSRDDKKPISYMAVIIQFCWHFFTIAARVITFALFASVFQLYFGIFIVLHWCIMTFWIVHCETEFCITKWEEIVFDMVVGIIYIFSWFNVKEGRTRCRLFIYYFVILLENTALSALWYLYKAPQIADAFAIPALCVVFSSFLTGVVFMLMYYAFFHPNGPRFGQSPSCACEDPAAAFTLPPDVATSTLRSISNNRSVVSDRDQKFAERDGCVPVFQVRPTAPSTPSSRPPRIEESVIKIDLFRNRYPAWERHVLDRSLRKAILAFECSPSPPRLQYKDDALIQERLEYETTL", "length": 650 }, "evidence": [ { "id": "E1BNK0", "url": "https://omabrowser.org/oma/group/E1BNK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BNK0", "url": "https://www.uniprot.org/uniprotkb/E1BNK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "engulfment of apoptotic cell", "id": "GO:0043652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043652", "evidence": [ { "database": "UniProtKB", "id": "E1BNK0", "url": "https://www.uniprot.org/uniprotkb/E1BNK0" } ], "pmid": "" }, { "name": "phosphatidylserine exposure on apoptotic cell surface", "id": "GO:0070782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070782", "evidence": [ { "database": "UniProtKB", "id": "E1BNK0", "url": "https://www.uniprot.org/uniprotkb/E1BNK0" } ], "pmid": "" }, { "name": "apoptotic process involved in development", "id": "GO:1902742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902742", "evidence": [ { "database": "UniProtKB", "id": "E1BNK0", "url": "https://www.uniprot.org/uniprotkb/E1BNK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "38663", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MUP9-1" ], "evidence": [ { "id": "38663", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38663" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1MUP9", "gene_name": "VAT1", "activity": [ { "ec_number": "1.6.5.5", "activity": "2 1,2-naphthoquinone + NADPH + H(+) = 2 1,2-naphthosemiquinone + NADP(+).", "evidence": [ { "id": "F1MUP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUP9" } ] }, { "ec_number": "1.6.5.5", "activity": "", "evidence": [ { "id": "F1MUP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUP9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNK0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 646, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNK0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNK0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 578 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 }, { "start_pos": 548, "end_pos": 550 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNM1-1", "uniprot_ac": "E1BNM1", "uniprot_id": "E1BNM1_BOVIN", "mass": { "chemical_mass": 58572.0, "monoisotopic_mass": 58572.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "E1BNM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNM1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNM1", "url": "https://www.uniprot.org/uniprotkb/E1BNM1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BNM1", "locus": {} } ], "crossref": [ { "id": "E1BNM1", "url": "https://alphafold.ebi.ac.uk/entry/E1BNM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000053351", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000053351", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11738:SF179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738:SF179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BNM1", "url": "https://www.uniprot.org/uniprotkb/E1BNM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNM1-1", "url": "https://www.uniprot.org/uniprotkb/E1BNM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LPGTLPKPIIWAEPGSVVPWGSPVTIWCRGTLGAQEFHLDKEGSLILWVRQNSLEPRDKARFSILHMGQDHAGSYRCYHSTRTGWSERSDPLQLVVTGSYSKPSLSALPSPVVMSGGNVTLQCGPSQGFNRFLLTKEGEDKSSWTLDGEQRTDGQTQALLPVGPVTPGHRWMFKCYSFYRHNPRVWSAPSDPLELLVSGQSGKPSLLTPQGPVITSGQNLTLQCRSDVSYTRFALSKEGGQDLPQRPAQRSQGRLAQADFPLGPVGTVHGGRYICYGGHGLSSEWSAPSEPLELLVAGEEPAGQPSLSVRPGPSVALGETVTLLCQSGERTDTFLLFKEGAAHRPLRLRSQDQDGRYQAEFSLSPVTSAHGGTYRCYRSLSTDPYLLSQPSEPLALVVSGEAQSVRQLSSSRLCPESVSGAPGLTWYLSVLIGVSVTFVLLLLVLLFLFLHHRGQDRRRKSRHQTEGNQGHGNNGSLLSRPPGAPSHTPSPLQAATSEAPQDVTYAQVNHSTVRRGTTTPLAPPSGEPPAEPSEYATLAIR", "length": 541, "header": "tr|E1BNM1-1|E1BNM1_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=5 CANONICAL=E1BNM1-1" }, "isoforms": [ { "isoform_ac": "E1BNM1-1", "url": "https://www.uniprot.org/uniprotkb/E1BNM1/entry#E1BNM1-1", "sequence": { "sequence": "LPGTLPKPIIWAEPGSVVPWGSPVTIWCRGTLGAQEFHLDKEGSLILWVRQNSLEPRDKARFSILHMGQDHAGSYRCYHSTRTGWSERSDPLQLVVTGSYSKPSLSALPSPVVMSGGNVTLQCGPSQGFNRFLLTKEGEDKSSWTLDGEQRTDGQTQALLPVGPVTPGHRWMFKCYSFYRHNPRVWSAPSDPLELLVSGQSGKPSLLTPQGPVITSGQNLTLQCRSDVSYTRFALSKEGGQDLPQRPAQRSQGRLAQADFPLGPVGTVHGGRYICYGGHGLSSEWSAPSEPLELLVAGEEPAGQPSLSVRPGPSVALGETVTLLCQSGERTDTFLLFKEGAAHRPLRLRSQDQDGRYQAEFSLSPVTSAHGGTYRCYRSLSTDPYLLSQPSEPLALVVSGEAQSVRQLSSSRLCPESVSGAPGLTWYLSVLIGVSVTFVLLLLVLLFLFLHHRGQDRRRKSRHQTEGNQGHGNNGSLLSRPPGAPSHTPSPLQAATSEAPQDVTYAQVNHSTVRRGTTTPLAPPSGEPPAEPSEYATLAIR", "length": 541, "header": "tr|E1BNM1-1|E1BNM1_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=5 CANONICAL=E1BNM1-1" }, "locus": { "chromosome": "NKLS02000591.1", "start_pos": 162492, "end_pos": 156762, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007679.8", "url": "https://www.ensembl.org/id/ENSBTAT00000007679.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007679.8", "url": "https://www.ensembl.org/id/ENSBTAP00000007679.8" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 166, "start_aa": "Thr", "end_pos": 166, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr166", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "immune response-inhibiting cell surface receptor signaling pathway", "id": "GO:0002767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002767", "evidence": [ { "database": "UniProtKB", "id": "E1BNM1", "url": "https://www.uniprot.org/uniprotkb/E1BNM1" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "E1BNM1", "url": "https://www.uniprot.org/uniprotkb/E1BNM1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BNM1", "url": "https://www.uniprot.org/uniprotkb/E1BNM1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "inhibitory MHC class I receptor activity", "id": "GO:0032396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032396", "evidence": [ { "database": "UniProtKB", "id": "E1BNM1", "url": "https://www.uniprot.org/uniprotkb/E1BNM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNM1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 541, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNM1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNM1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNM1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 93, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 166 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 474, "end_pos": 476 }, { "start_pos": 509, "end_pos": 511 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNM2-1", "uniprot_ac": "E1BNM2", "uniprot_id": "E1BNM2_BOVIN", "mass": { "chemical_mass": 117053.0, "monoisotopic_mass": 117053.0 }, "refseq": { "ac": "XP_002692127", "name": "integrin alpha-8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692127" }, "gene_names": [ { "name": "ITGA8", "type": "recommended", "evidence": [ { "id": "E1BNM2", "database": "UniProtKB", "url": 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It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.", "evidence": [ { "database": "UniProtKB", "id": "E1BNM2", "url": "https://www.uniprot.org/uniprotkb/E1BNM2#function" }, { "database": "UniProtKB", "id": "ARBA00057659", "url": "https://www.uniprot.org/uniprotkb/ARBA00057659#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNM2", "url": "https://www.uniprot.org/uniprotkb/E1BNM2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ITGA8", "url": "https://www.uniprot.org/uniprotkb/E1BNM2", "locus": { "chromosome": "13", "start_pos": 30055079, "end_pos": 30242636, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007602", "url": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511976", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511976", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR23220", "url": 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"length": 1062, "header": "tr|E1BNM2-1|E1BNM2_BOVIN Isoform 1 of Integrin alpha-8 OS=Bos taurus OX=9913 GN=ITGA8 PE=3 SV=4 CANONICAL=E1BNM2-1" }, "locus": { "chromosome": "13", "start_pos": 30242437, "end_pos": 30056083, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039425.6", "url": "https://www.ensembl.org/id/ENSBTAT00000039425.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039219.6", "url": "https://www.ensembl.org/id/ENSBTAP00000039219.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511976", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511976", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNP7-1", "uniprot_ac": "E1BNP7", "uniprot_id": "E1BNP7_BOVIN", "mass": { "chemical_mass": 49551.0, "monoisotopic_mass": 49551.0 }, "refseq": { "ac": "NP_001179258", "name": "transcription factor AP-2-delta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179258" }, "gene_names": [ { "name": "TFAP2D", "type": "recommended", "evidence": [ { "id": "E1BNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNP7" } ] }, { "name": "TFAP2D", "type": "synonym", "evidence": [ { "id": "NP_001179258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179258" } ] } ], "protein_names": [ { "name": "Transcription factor AP-2 delta", "type": "synonym", "evidence": [ { "id": "E1BNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNP7/entry#names_and_taxonomy" } ] }, { "name": "transcription factor AP-2-delta", "type": "synonym", "evidence": [ { "id": "NP_001179258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179258" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNP7", "url": "https://www.uniprot.org/uniprotkb/E1BNP7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TFAP2D", "url": "https://www.uniprot.org/uniprotkb/E1BNP7", "locus": { "chromosome": "23", "start_pos": 23337345, "end_pos": 23277603, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020425", "url": "https://www.ensembl.org/id/ENSBTAG00000020425" } ] } } ], "crossref": [ { "id": "E1BNP7", "url": "https://alphafold.ebi.ac.uk/entry/E1BNP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020425", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020425", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539910", "url": "https://www.ncbi.nlm.nih.gov/gene/539910", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539910", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539910", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYEFQHG", "url": "https://omabrowser.org/oma/group/HYEFQHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNP7", "url": "https://www.orthodb.org/?gene=E1BNP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10812", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10812", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10812:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10812:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03299", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03299", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8866904", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866904", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8866907", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866907", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179258", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179258", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BNP7", "url": "https://www.uniprot.org/uniprotkb/E1BNP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNP7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGLVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHGTSEKAPLRKTSEAAVKEGKTEKTD", "length": 452, "header": "tr|E1BNP7-1|E1BNP7_BOVIN Isoform 1 of Transcription factor AP-2 delta OS=Bos taurus OX=9913 GN=TFAP2D PE=3 SV=1 CANONICAL=E1BNP7-1" }, "isoforms": [ { "isoform_ac": "E1BNP7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNP7/entry#E1BNP7-1", "sequence": { "sequence": "MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGLVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHGTSEKAPLRKTSEAAVKEGKTEKTD", "length": 452, "header": "tr|E1BNP7-1|E1BNP7_BOVIN Isoform 1 of Transcription factor AP-2 delta OS=Bos taurus OX=9913 GN=TFAP2D PE=3 SV=1 CANONICAL=E1BNP7-1" }, "locus": { "chromosome": "23", "start_pos": 23337170, "end_pos": 23278115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027219.3", "url": "https://www.ensembl.org/id/ENSBTAT00000027219.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027219.2", "url": "https://www.ensembl.org/id/ENSBTAP00000027219.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539910", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539910", "resource": "KEGG Pathway" }, { "id": "R-BTA-8866904", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866904", "resource": "Reactome", "description": "Negative regulation of activity of TFAP2 (AP-2) family transcription factors" }, { "id": "R-BTA-8866907", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866907", "resource": "Reactome", "description": "Activation of the TFAP2 (AP-2) family of transcription factors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V0Q4-1", "protein_name": "Transcription factor AP-2 delta", "gene_name": "TFAP2D", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGLVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHGTSEKAPLRKTSEAAVKEGKTEKTD", "length": 452 }, "evidence": [ { "id": "E1BNP7", "url": "https://omabrowser.org/oma/group/E1BNP7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZJN7-1", "protein_name": "Transcription factor AP-2 delta", "gene_name": "Tfap2d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGIVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHANSEKAPLRKASEAAVKEGKTEKTD", "length": 452 }, "evidence": [ { "id": "E1BNP7", "url": "https://omabrowser.org/oma/group/E1BNP7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7HFB1-1", "protein_name": "Transcription factor AP-2-delta isoform X1", "gene_name": "Tfap2d", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNLKFFCSPLSPSSFQIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGIVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHANSEKAPLRKASEAAVKEGKTEKTD", "length": 456 }, "evidence": [ { "id": "E1BNP7", "url": "https://omabrowser.org/oma/group/E1BNP7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1C135-1", "protein_name": "Transcription factor AP-2 delta", "gene_name": "TFAP2D", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVNPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAASGADDLQSSVEAQCGLVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHIARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTSHKNGGAAESGQGHANSEKAPLRKTSEAAVKEGKTEKTD", "length": 452 }, "evidence": [ { "id": "E1BNP7", "url": "https://omabrowser.org/oma/group/E1BNP7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5RJ20-1", "protein_name": "Transcription factor AP-2-delta", "gene_name": "tfap2d", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSATFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSSVAYSSSSPLTYPATGTEFASPYFPTNHQYTPLHHQSFHYEFQHSHPAVNPDAYSLNSLHHSQQYYQQLHHGEPADFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSIMSHGSQYGMHPEQRLLPGAGLGLPPPGADDLQGSVDAQCGLVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPTKAVGEHLARQHTEPKEQNARKKMVLATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTILSEMLNYLEKHSANKSTGTPDTNQINSNSDKTLRKTEAPTKDGKIEKTE", "length": 450 }, "evidence": [ { "id": "E1BNP7", "url": "https://omabrowser.org/oma/group/E1BNP7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7Z6R9-1", "protein_name": "Transcription factor AP-2-delta", "gene_name": "TFAP2D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGLVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHANSEKAPLRKTSEAAVKEGKTEKTD", "length": 452 }, "evidence": [ { "id": "E1BNP7", "url": "https://omabrowser.org/oma/group/E1BNP7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZK0-1", "protein_name": "Transcription factor AP-2-delta", "gene_name": "Tfap2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGIVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHANSEKAPLRKASEAAVKEGKTEKTD", "length": 452 }, "evidence": [ { "id": "E1BNP7", "url": "https://omabrowser.org/oma/group/E1BNP7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BNP7", "url": "https://www.uniprot.org/uniprotkb/E1BNP7" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "E1BNP7", "url": "https://www.uniprot.org/uniprotkb/E1BNP7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BNP7", "url": "https://www.uniprot.org/uniprotkb/E1BNP7" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "E1BNP7", "url": "https://www.uniprot.org/uniprotkb/E1BNP7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BNP7", "url": "https://www.uniprot.org/uniprotkb/E1BNP7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "E1BNP7", "url": "https://www.uniprot.org/uniprotkb/E1BNP7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BNP7", "url": "https://www.uniprot.org/uniprotkb/E1BNP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" } ], 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377389" }, "gene_names": [ { "name": "OR8K1B", "type": "recommended", "evidence": [ { "id": "E1BNR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNR4" } ] }, { "name": "OR8K1B", "type": "synonym", "evidence": [ { "id": "NP_001377389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377389" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "E1BNR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNR4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8K1", "type": "synonym", "evidence": [ { "id": "NP_001377389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377389" } ] }, { "name": "olfactory receptor family 8 subfamily K member 1B", "type": "synonym", "evidence": [ { "id": "NP_001377389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377389" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377389", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377389" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BNR4", "url": "https://www.uniprot.org/uniprotkb/E1BNR4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNR4", "url": "https://www.uniprot.org/uniprotkb/E1BNR4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8K1B", "url": "https://www.uniprot.org/uniprotkb/E1BNR4", "locus": { "chromosome": "15", "start_pos": 79589827, "end_pos": 79588886, "strand": "-", "evidence": 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"https://www.uniprot.org/uniprotkb/E1BNS4/entry#E1BNS4-1", "sequence": { "sequence": "MQQAVEQGLDLAEYVIATAQQRPPKRKYSSSGETSLQEKLYDIYVEECEEEPEVTEELRSNVNLLEKLLRRESLPCLVINLYPGKQGYSLMLKGENGSFSESIRLPYEEREFLEYLDAEELPPVLLNFLEKSAVNVFHQGCVIAEIRDYRQSGAGEPPRYQSRHILLRPTMQTLVCDVEAIASDHQNWTQEDKLLLESQLILATAEPLCLDPSVSVACTENRLLYNKQKLNTLAMKRSLKRFSVPALNQQQELSHCPPPPEPRIMTSCKKIRESKTNELYDLKISKAGDCADTWIQRPCNLAVPAQVDVQKYATGKKPVRYEESQPTQKVLGDSAVGCEAAYQSQATRLTVRQPTDNSLATGNGSENEATREREPCLPQPSTDDQFKSFLPRPQTDAGRVGSRSEQLVQKSAQCPVQMSPSSSGSAHLRQPSPGTRSAQPRAASIRSSVPDRGARPPPPLKRRPWSLEKSSCSDSFTSQQAGSSQAHPSAGPAPQPPSLSQRSSVQLNRSILLPAAAPSTVVMLQRIPDVQVTTISPGLKEIRLVGPFCCSQASGRGCAPRAPAPVGIQPGQQPAAQPLNLQPAAPLGLPPPASLPSPTPRTVQVFLKKASGLKQYTVMQLPQGLVVWSNQHGVLQSRFYQVLTQQLSPQPCPVSHRQPAEQPSVPKEMSEETDNKPVLLDQPSCTNALQILLRTDLISLRSTTQRGQRSDPESIRASCSPPWTSSGIVPALLRSEAVQWPIAKKSLCSACEPTRHQNSEFVYLLCFVLTDLLKCRW", "length": 777, "header": "tr|E1BNS4-1|E1BNS4_BOVIN Isoform 1 of Spt20-like SEP domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=E1BNS4-1" }, "locus": { "chromosome": "X", "start_pos": 119021877, "end_pos": 119016521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038974.5", "url": "https://www.ensembl.org/id/ENSBTAT00000038974.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038778.5", "url": "https://www.ensembl.org/id/ENSBTAP00000038778.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 599, "start_aa": "Thr", "end_pos": 599, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr599", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BNS4", "url": "https://www.uniprot.org/uniprotkb/E1BNS4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "E1BNS4", "url": "https://www.uniprot.org/uniprotkb/E1BNS4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "E1BNS4", "url": "https://www.uniprot.org/uniprotkb/E1BNS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNS4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 777, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNS4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNS4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS4" }, { "id": "PF12090", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12090" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Spt20-like SEP", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 218, "start_aa": "Leu", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 599 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNT1-1", "uniprot_ac": "E1BNT1", "uniprot_id": "E1BNT1_BOVIN", "mass": { "chemical_mass": 45617.0, "monoisotopic_mass": 45617.0 }, "refseq": { "ac": "XP_015316083", "name": "lipase member J isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316083" }, "gene_names": [ { "name": "LIPJ", "type": "recommended", "evidence": [ { "id": "E1BNT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNT1" } ] }, { "name": "LIPJ", "type": "synonym", "evidence": [ { "id": "XP_015316083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316083" } ] } ], "protein_names": [ { "name": "Lipase", "type": "recommended", "evidence": [ { "id": "E1BNT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNT1/entry#names_and_taxonomy" } ] }, { "name": "lipase member J isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015316083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316083" } ] } ], "function": [ { "annotation": "Catalyzes the hydrolysis of triacylglycerols to yield free fatty acids, diacylglycerol, monoacylglycerol, and glycerol. Shows a preferential hydrolysis at the sn-3 position of triacylglycerol.", "evidence": [ { "database": "UniProtKB", "id": "E1BNT1", "url": "https://www.uniprot.org/uniprotkb/E1BNT1#function" }, { "database": "UniProtKB", "id": "ARBA00045163", "url": "https://www.uniprot.org/uniprotkb/ARBA00045163#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNT1", "url": "https://www.uniprot.org/uniprotkb/E1BNT1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LIPJ", "url": "https://www.uniprot.org/uniprotkb/E1BNT1", "locus": { "chromosome": "26", "start_pos": 10214257, "end_pos": 10177759, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038063", "url": "https://www.ensembl.org/id/ENSBTAG00000038063" } ] } } ], "crossref": [ { "id": "E1BNT1", "url": "https://alphafold.ebi.ac.uk/entry/E1BNT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000038063", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038063", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515342", "url": "https://www.ncbi.nlm.nih.gov/gene/515342", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515342", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515342", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BNT1", "url": "https://www.orthodb.org/?gene=E1BNT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11005", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11005", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015316083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12044", "url": "https://www.rhea-db.org/rhea/12044", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "39931", "url": "https://www.rhea-db.org/rhea/39931", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40047", "url": "https://www.rhea-db.org/rhea/40047", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BNT1", "url": "https://www.uniprot.org/uniprotkb/E1BNT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNT1-1", "url": "https://www.uniprot.org/uniprotkb/E1BNT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWYLFKVMSFILILGTTHGVFRKQRSVNPEASMNISQIISYWGYPDEEYDITTEDGYILGLYRIPYGKTNSENNSVQRLVVYLQHGLLTSASSWISNLPNNSLGFLLADAGYDVWMGNSRGTTWSRKHLYLTTNSKEFWAFSFDEMAKYDLPASIDFIVKQTQQQQIFYVGHSQGTTIAFITFSTIPKIAERIKVFFALAPVFSIKYSKSPLIKMAYNWKSLIKFFSGSKEFLPNTSFKRFVGSKLCPLKIFVKICRDVLFMISGYDLKNLNTSRVDVYMSQNPAGTSVQNMVHWSQLFNSSHLKAFDWGSPDLNLVHFNQTTSPLYNVTSMNVPTATWSGDSDLLADPEDVKILLPEITNHIYHKTISYYNHVDFLFGLDVYHQVYSEIIDIIQGNP", "length": 398, "header": "tr|E1BNT1-1|E1BNT1_BOVIN Isoform 1 of Lipase OS=Bos taurus OX=9913 GN=LIPJ PE=3 SV=4 CANONICAL=E1BNT1-1" }, "isoforms": [ { "isoform_ac": "E1BNT1-1", "url": "https://www.uniprot.org/uniprotkb/E1BNT1/entry#E1BNT1-1", "sequence": { "sequence": "MWYLFKVMSFILILGTTHGVFRKQRSVNPEASMNISQIISYWGYPDEEYDITTEDGYILGLYRIPYGKTNSENNSVQRLVVYLQHGLLTSASSWISNLPNNSLGFLLADAGYDVWMGNSRGTTWSRKHLYLTTNSKEFWAFSFDEMAKYDLPASIDFIVKQTQQQQIFYVGHSQGTTIAFITFSTIPKIAERIKVFFALAPVFSIKYSKSPLIKMAYNWKSLIKFFSGSKEFLPNTSFKRFVGSKLCPLKIFVKICRDVLFMISGYDLKNLNTSRVDVYMSQNPAGTSVQNMVHWSQLFNSSHLKAFDWGSPDLNLVHFNQTTSPLYNVTSMNVPTATWSGDSDLLADPEDVKILLPEITNHIYHKTISYYNHVDFLFGLDVYHQVYSEIIDIIQGNP", "length": 398, "header": "tr|E1BNT1-1|E1BNT1_BOVIN Isoform 1 of Lipase OS=Bos taurus OX=9913 GN=LIPJ PE=3 SV=4 CANONICAL=E1BNT1-1" }, "locus": { "chromosome": "26", "start_pos": 10214232, "end_pos": 10195079, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049487.6", "url": "https://www.ensembl.org/id/ENSBTAT00000049487.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046375.5", "url": "https://www.ensembl.org/id/ENSBTAP00000046375.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515342", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515342", "resource": "KEGG Pathway" }, { "id": "R-BTA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "E1BNT1", "url": "https://www.uniprot.org/uniprotkb/E1BNT1" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "E1BNT1", "url": "https://www.uniprot.org/uniprotkb/E1BNT1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "E1BNT1", "url": "https://www.uniprot.org/uniprotkb/E1BNT1" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "E1BNT1", "url": "https://www.uniprot.org/uniprotkb/E1BNT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12044", "name": "", "equation": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PK46-1", "A0A3Q1LV96-1", "A0A3Q1MLE6-1", "Q3SZ79-1", "E1BJQ9-1", "Q5EA42-1", "P11151-1", "P16386-1", "P30122-1", "Q29458-1", "Q2KI18-1", "F1MC21-1", "Q0P5B7-1", "A0A3Q1M7B8-1", "F6RA94-1", "G5E5T0-1", "A0A3Q1LR40-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "12044", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12044" } ] }, { "id": "39931", "name": "", "equation": "1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoate + 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"https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.79", "activity": "", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] } ] }, { "uniprot_ac": "A0AAA9S3G3", "gene_name": "LOC100297709", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] } ] }, { "uniprot_ac": "A0ABI0NMZ2", "gene_name": "PNPLA3", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] } ] }, { "uniprot_ac": "A5PK46", "gene_name": "PNLIPRP2", "activity": [ { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJQ9" } ] } ] }, { "uniprot_ac": "F1MC21", "gene_name": "PNLIPRP3", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "F1MC21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC21" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "F1MC21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC21" } ] } ] }, { "uniprot_ac": "F6RA94", "gene_name": "DAGLB", "activity": [ { "ec_number": "3.1.1.116", "activity": "a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "F6RA94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RA94" } ] }, { "ec_number": "3.1.1.116", "activity": "", "evidence": [ { "id": "F6RA94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RA94" } ] } ] }, { 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1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "P11151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11151" } ] }, { "ec_number": "3.1.1.34", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "P11151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11151" } ] }, { "ec_number": "3.1.1.34", "activity": "", "evidence": [ { "id": "P11151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11151" } ] } ] }, { "uniprot_ac": "P16386", "gene_name": "LIPE", "activity": [ { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "P16386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16386" } ] }, { "ec_number": "3.1.1.79", "activity": "a monoacylglycerol + H2O = glycerol + a fatty acid + H(+).", "evidence": [ { "id": "P16386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16386" } ] }, { "ec_number": "3.1.1.79", "activity": "", "evidence": [ { "id": "P16386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16386" } ] } ] }, { "uniprot_ac": "P30122", "gene_name": "CEL", "activity": [ { "ec_number": "3.1.1.13", "activity": "a cholesterol ester + H2O = cholesterol + a fatty acid + H(+).", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.6", "activity": "an acetyl ester + H2O = an aliphatic alcohol + acetate + H(+).", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.13", "activity": "", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.6", "activity": "", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] } ] }, { "uniprot_ac": "Q0P5B7", "gene_name": "AADAC", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "Q0P5B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5B7" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "Q0P5B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5B7" } ] } ] }, { "uniprot_ac": "Q29458", "gene_name": "LIPF", "activity": [ { "ec_number": "3.1.1.3", "activity": 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"url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] } ] }, { "uniprot_ac": "Q3SZ79", "gene_name": "LIPC", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q3SZ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZ79" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "Q3SZ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZ79" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q3SZ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZ79" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "Q3SZ79", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA42" } ] }, { "ec_number": "3.1.1.23", "activity": "", "evidence": [ { "id": "Q5EA42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA42" } ] }, { "ec_number": "3.1.1.79", "activity": "", "evidence": [ { "id": "Q5EA42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA42" } ] }, { "ec_number": "3.1.1.6", "activity": "", "evidence": [ { "id": "Q5EA42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA42" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNT1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 398, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNT1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNT1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNT1", "database": "UniProtKB", "url": 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{ "uniprot_canonical_ac": "E1BNW4-1", "uniprot_ac": "E1BNW4", "uniprot_id": "E1BNW4_BOVIN", "mass": { "chemical_mass": 78589.0, "monoisotopic_mass": 78589.0 }, "refseq": { "ac": "NP_001422187", "name": "voltage-gated chloride channel TMC4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422187" }, "gene_names": [ { "name": "TMC4", "type": "recommended", "evidence": [ { "id": "E1BNW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW4" } ] }, { "name": "TMC4", "type": "synonym", "evidence": [ { "id": "NP_001422187", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422187" } ] } ], "protein_names": [ { "name": "Transmembrane channel-like protein", "type": "recommended", "evidence": [ { "id": "E1BNW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW4/entry#names_and_taxonomy" } ] }, { "name": "voltage-gated chloride channel TMC4", "type": "synonym", "evidence": [ { "id": "NP_001422187", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422187" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNW4", "url": "https://www.uniprot.org/uniprotkb/E1BNW4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMC4", "url": "https://www.uniprot.org/uniprotkb/E1BNW4", "locus": { "chromosome": "18", "start_pos": 63238065, "end_pos": 63227968, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020062", "url": "https://www.ensembl.org/id/ENSBTAG00000020062" } ] } } ], "crossref": [ { "id": "E1BNW4", "url": "https://alphafold.ebi.ac.uk/entry/E1BNW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020062", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020062", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "512610", "url": "https://www.ncbi.nlm.nih.gov/gene/512610", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TLQPWAW", "url": "https://omabrowser.org/oma/group/TLQPWAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNW4", "url": "https://www.orthodb.org/?gene=E1BNW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001422187", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422187", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BNW4", "url": "https://www.uniprot.org/uniprotkb/E1BNW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNW4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEERPPWDPEAWGSVEGRPAPRAARTGPSLSSVLNELPSAATLRYRGPGVLPWGSEEAEDEEAWRSMQTSADAALQEQPEPGASRELPWPMLARRAHRQRLARDRVAQGAGSTGAQWTRLIRRSKEKVREGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLTACMVLLPTWLEGTPPGPPAPNASSPCGSYNPGSHGLVPFATELFNLLSGEGFLEWSPLFYGFYPPRPHLAITYLCAAFAIGLLYLLLILHRSVSGLKQTLLAESEALTRYSHRVFSAWDFGLSGEVHVRLRQRLILYELQVELEEARVRRRAAVRTLGQQARLWSVRLLLNLVVLALLGAAFYGIYWATGATVGLQDKPLIQRTPVLKLVVDYLPSIFISLVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTVSLRLVSLLVLLFSLWNEITCGGDAEDERCKTCGYNYKELPCWETRMGQEMYKLLLFDLLTGLAVILLYQFPRKLLCGLCPGALGRFARTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKITLFSTCSPASRTFRASTVNFFFPLVLLLGLAISAVPVLYSIFLIPPSKLCGPFRGQSSIWVVIPASIRELPQTAQNVLFFLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQIQTEAQNKVFLAQRAVALSSADRTL", "length": 705, "header": "tr|E1BNW4-1|E1BNW4_BOVIN Isoform 1 of Transmembrane channel-like protein OS=Bos taurus OX=9913 GN=TMC4 PE=3 SV=3 CANONICAL=E1BNW4-1" }, "isoforms": [ { "isoform_ac": "E1BNW4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNW4/entry#E1BNW4-1", "sequence": { "sequence": "MEERPPWDPEAWGSVEGRPAPRAARTGPSLSSVLNELPSAATLRYRGPGVLPWGSEEAEDEEAWRSMQTSADAALQEQPEPGASRELPWPMLARRAHRQRLARDRVAQGAGSTGAQWTRLIRRSKEKVREGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLTACMVLLPTWLEGTPPGPPAPNASSPCGSYNPGSHGLVPFATELFNLLSGEGFLEWSPLFYGFYPPRPHLAITYLCAAFAIGLLYLLLILHRSVSGLKQTLLAESEALTRYSHRVFSAWDFGLSGEVHVRLRQRLILYELQVELEEARVRRRAAVRTLGQQARLWSVRLLLNLVVLALLGAAFYGIYWATGATVGLQDKPLIQRTPVLKLVVDYLPSIFISLVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTVSLRLVSLLVLLFSLWNEITCGGDAEDERCKTCGYNYKELPCWETRMGQEMYKLLLFDLLTGLAVILLYQFPRKLLCGLCPGALGRFARTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKITLFSTCSPASRTFRASTVNFFFPLVLLLGLAISAVPVLYSIFLIPPSKLCGPFRGQSSIWVVIPASIRELPQTAQNVLFFLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQIQTEAQNKVFLAQRAVALSSADRTL", "length": 705, "header": "tr|E1BNW4-1|E1BNW4_BOVIN Isoform 1 of Transmembrane channel-like protein OS=Bos taurus OX=9913 GN=TMC4 PE=3 SV=3 CANONICAL=E1BNW4-1" }, "locus": { "chromosome": "18", "start_pos": 63237854, "end_pos": 63227989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026728.8", "url": "https://www.ensembl.org/id/ENSBTAT00000026728.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026728.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026728.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1RNH1-1", "protein_name": "Transmembrane channel-like protein", "gene_name": "TMC4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEESWAWEPEAWGSSGGWPAPREASTGPSLSSVLNELPSAATLRYRGPGVLPWGALEEEEEERSIQAFTESARKELQEPRPSRELPWPMQARRVHRQNLARDQVALNSGSRVAHWALLLRRSKEKVREGLKTLKPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLKACMILLPTWLEGTPPGPPAANASSPCGSYNPRPHGLVTFPTQLFNLLSGEGFLEWSPLFYGFYPPRPHLAITYLCSVFAIGLLYLLLILHRSVSGLKQTLLAESGVLTSYSHRVFSAWDFGLSGEVHVRLRQRNILFELQVELEEAVVRYQAAVRTLGQQARVWLVRVLINLAVLALLGAAFYGVYWATKATVNLQDMPPVQKMPLLKLGVNYLPSIFISVVNFILPVLFKLIAPLEGYTRSRQIVFILLRTVFLRLASLLVLLGTLWNQISCGEAECKACGYNYKELPCWETRLGQEMYKLLLFDLLSGLAVMLLIQFPRKLLCGLCPGALGRFARTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTAKFLLLFYLKKLTLFSTCSPASRTFRASTVNFFFPLVLLLGLAISAVPVLYGIFVIPPSKLCGPFRGQLSIWSEIPKSIGSLPETAQNFLFFLGTQAFAVPLLLLSSILMAYTVALANSYGRLISELKRQIETEAQNKVFLAQRAVALSSANGAL", "length": 699 }, "evidence": [ { "id": "E1BNW4", "url": "https://omabrowser.org/oma/group/E1BNW4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q496Z4-1", "protein_name": "Voltage-gated chloride channel TMC4", "gene_name": "Tmc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEESPREAWAQFPAWSSSRKARTGPSLASVLNDLPSAATLRYRGPGVLPWGTLDENDDEGRSLQAFAETAQMESQPSRELPWPMQARRAHRKSQAREQVASGSESRAAYWTQQLSRTKGKMKEGFQTIQPWAWTLKKIGGQFGAGTESYFSLLRFLLFLNLGASVIEVCMKLIPTWLEGAPPGPPGPNISSPCGSYIPHTQGLVTFPTQLFNLLSGEGYLEWSPLFYGFYPPRSNLAITYLCSVFAIGLIYLLFILHRSVSGLKETLLAESDVLTSYSHRVFSAWNFGLCGDMHVRLRQRIILYELQVDLEEAAVRRRATEQTLGQRVKVWSMRALLNLLVLALLGAAFYGIYWATEYTVTLQETPVVQQTPLLKLLVNYLPSIFISVFNFVLPPAFTFIASLEGYTHSRQIVLILLRTVFLRLASLVFLLFSLWNQITCGGNMEAEECKACGYNYKEIPCWETRLGQEMYKLVLFDLLMGLLVTLLIQFPRKILCGLCPGALGRLSGTLEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLINTAKFLILFWLKKITLFSIYSPASRTFRASTANFFFPLVLLVGLAISAVPVLYSIFLIPPSKLCGPFQGKLSIWAQIPESIESLPQTAQNFLYFLGTQAFTVPLLIVSSILMMYTVALANCYGRLISELKRQIETEVQNKVFLAQRAVALSSRNGVS", "length": 698 }, "evidence": [ { "id": "E1BNW4", "url": "https://omabrowser.org/oma/group/E1BNW4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TQ65-1", "protein_name": "Voltage-gated chloride channel TMC4", "gene_name": "Tmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAWGQSPACSSSRKARTGPSLASVLNDLPSAATLRYRGPGVLPWGTLDEDDDEGGRSLQAFAETAQMESHPSRELPWPMQARRAHRKSQATGQLASGSESRAAYWTRQLSRTKGKMKEGFQTIQPWAWTLKKIGGQFGAGTESYFSLLRFLLFLNLVASVIEICMKLIPTWLEGAPPGPPGPNISSPCGSYIPHTHGLVAFPTQLFNLLSGEGYLEWSPLFYGFYPPRSNLAITYLCSVFAISVIYLLCILRRSVSGLKETLLAESDILTSYSHRVFSAWNFGLCGDVHVRLRQRIILYELQVDLEEAVVRRRAAEQTLSQRAKVWSMRALLNVLVLALLGAAFYGIYWATEYTLTLQETPLVRQTPLFKLLVDYLPSIFISLFNFVLPPVFKFIASLEGYTQSRQIVLILLRTVFLRLASLVFLLVSLWSQITCGGNMEAEGCKACGYNYKEIPCWETRLGQEMYKLVLFDLLMGLLVTLLVQFPRKILCGLCPGALGRLSGTLEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLINTAKFLILFCLKKITLFSIYSPASRTFRASTANFFFPLVLLVGLAISAVPVLYSIFLIPPSKLCGPFRGKLSIWAQIPEAIESLPQTAQNFLYFLGTQAFTVPLLILSSILMMYTVALANCYGRLISELKRQIETEVQNKVFLAQRAVALSSRNGTS", "length": 694 }, "evidence": [ { "id": "E1BNW4", "url": "https://omabrowser.org/oma/group/E1BNW4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BNW4", "url": "https://www.uniprot.org/uniprotkb/E1BNW4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mechanosensitive monoatomic ion channel activity", "id": "GO:0008381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008381", "evidence": [ { "database": "UniProtKB", "id": "E1BNW4", "url": "https://www.uniprot.org/uniprotkb/E1BNW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNW4-F1", "pdb_chain": "global", "start_pos": 1, 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"categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BNW6", "url": "https://www.uniprot.org/uniprotkb/E1BNW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNW6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKTNYYTQKLRLLKEFPCLGQEGLDKILQIVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQIACTAIFIVWGVLVHLVIPPFVFMVTEEWDYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVAGSTAAKDINIFSFLSKKEETYNDLIKQIGKKAMKTGGGGERIPGPGPQGGGLPALPSSLAPLAVYSKNRVPSLEEVSQTLRTKGHISRPPGEEAVAGGPKEVSPTSEVSINQLDRISEEGEPWDAQDYHPLIFQNANITFVSAEAGLSDEETSKSSLEDNLAQEERPQEGAVAEAPLTLGEFPSSDESTFTSTESELSVPYEQLMNEYNKASGPQGT", "length": 497 }, "evidence": [ { "id": "E1BNW6", "url": "https://omabrowser.org/oma/group/E1BNW6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I2N9-1", "protein_name": "Potassium channel subfamily K member 5", "gene_name": "Kcnk5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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{ "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1BNW7-1", "uniprot_ac": "E1BNW7", "uniprot_id": "E1BNW7_BOVIN", "mass": { "chemical_mass": 62106.0, "monoisotopic_mass": 62106.0 }, "refseq": { "ac": "NP_001179536", "name": "acetyl-coenzyme A thioesterase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179536" }, "gene_names": [ { "name": "ACOT12", "type": "recommended", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ] }, { "name": "ACOT12", "type": "synonym", "evidence": [ { "id": "NP_001179536", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179536" } ] } ], "protein_names": [ { "name": "Acetyl-coenzyme A thioesterase", "type": "recommended", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7/entry#names_and_taxonomy" } ] }, { "name": "3.1.2.1", "type": "synonym", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7/entry#names_and_taxonomy" } ] }, { "name": "Acyl-CoA thioester hydrolase 12", "type": "synonym", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7/entry#names_and_taxonomy" } ] }, { "name": "Acyl-coenzyme A thioesterase 12", "type": "synonym", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7/entry#names_and_taxonomy" } ] }, { "name": "Cytoplasmic acetyl-CoA hydrolase 1", "type": "synonym", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7/entry#names_and_taxonomy" } ] }, { "name": "acetyl-coenzyme A thioesterase", "type": "synonym", "evidence": [ { "id": "NP_001179536", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179536" } ] } ], "function": [ { "annotation": "Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes acetyl-CoA.", "evidence": [ { "database": "UniProtKB", "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7#function" }, { "database": "UniProtKB", "id": "ARBA00060138", "url": "https://www.uniprot.org/uniprotkb/ARBA00060138#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ACOT12", "url": "https://www.uniprot.org/uniprotkb/E1BNW7", "locus": { "chromosome": "7", "start_pos": 81312801, "end_pos": 81354055, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011110", "url": "https://www.ensembl.org/id/ENSBTAG00000011110" } ] } } ], "crossref": [ { "id": "E1BNW7", "url": "https://alphafold.ebi.ac.uk/entry/E1BNW7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011110", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011110", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03442", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03442", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08914", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08914", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "525155", "url": "https://www.ncbi.nlm.nih.gov/gene/525155", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:525155", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525155", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DPHYMSC", "url": "https://omabrowser.org/oma/group/DPHYMSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNW7", "url": "https://www.orthodb.org/?gene=E1BNW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11049", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11049", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11049:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11049:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01852", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01852", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-77289", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77289", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179536", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179536", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20289", "url": "https://www.rhea-db.org/rhea/20289", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40111", "url": "https://www.rhea-db.org/rhea/40111", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40115", "url": "https://www.rhea-db.org/rhea/40115", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNW7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELERPAPAEVRMSQAIQPAHANSRGELSAGQLLKWIDTTACLAAEKHAGVSCVTASVDDIQFEATARVGQVITIKAKVSRAFSTSMEISIKVTVEDMLTGTEKLVSVAFSTFVAKPVGKEKIQLKPVTLLTEQDHVEHNLASERRKVRLQHEDTFKNLMKESGKFDDPICDEEEGTVSTKGTSVQSIELVLPPHANHHGNTFGGQIMAWMEAVATISASRLCRAHPVLKSVDMFKFRGPSTVGDRLVFNAIVNNTFQTCVEVGVRVEAFDCQEWSKSRGRHINSAFLIYNAVDDKEELITFPKIKPMSKDDFRRYRGALARKRIRLGRKYVISHKEEVPLCIYWDIGNQVSLSNGNVEALKSLAAKSGWEVTSAVEKIKIYTLEEHDSLSVWVEKHVKRPAYLVYHLLSNFTKRPLWDPHYMSCEVIDRVSEDDQIYYITCPVVNNDKPKDLVVLVSRRRPLEDGHTYVVAVRSVILPSVPPSPQYVRSEIECAGFLIHATDSSSCTVSYFNQISASILPYFAGNLGGWSKSIEETAASCIQFIESATDDGLISIL", "length": 557, "header": "tr|E1BNW7-1|E1BNW7_BOVIN Isoform 1 of Acetyl-coenzyme A thioesterase OS=Bos taurus OX=9913 GN=ACOT12 PE=4 SV=2 CANONICAL=E1BNW7-1" }, "isoforms": [ { "isoform_ac": "E1BNW7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNW7/entry#E1BNW7-1", "sequence": { "sequence": "MELERPAPAEVRMSQAIQPAHANSRGELSAGQLLKWIDTTACLAAEKHAGVSCVTASVDDIQFEATARVGQVITIKAKVSRAFSTSMEISIKVTVEDMLTGTEKLVSVAFSTFVAKPVGKEKIQLKPVTLLTEQDHVEHNLASERRKVRLQHEDTFKNLMKESGKFDDPICDEEEGTVSTKGTSVQSIELVLPPHANHHGNTFGGQIMAWMEAVATISASRLCRAHPVLKSVDMFKFRGPSTVGDRLVFNAIVNNTFQTCVEVGVRVEAFDCQEWSKSRGRHINSAFLIYNAVDDKEELITFPKIKPMSKDDFRRYRGALARKRIRLGRKYVISHKEEVPLCIYWDIGNQVSLSNGNVEALKSLAAKSGWEVTSAVEKIKIYTLEEHDSLSVWVEKHVKRPAYLVYHLLSNFTKRPLWDPHYMSCEVIDRVSEDDQIYYITCPVVNNDKPKDLVVLVSRRRPLEDGHTYVVAVRSVILPSVPPSPQYVRSEIECAGFLIHATDSSSCTVSYFNQISASILPYFAGNLGGWSKSIEETAASCIQFIESATDDGLISIL", "length": 557, "header": "tr|E1BNW7-1|E1BNW7_BOVIN Isoform 1 of Acetyl-coenzyme A thioesterase OS=Bos taurus OX=9913 GN=ACOT12 PE=4 SV=2 CANONICAL=E1BNW7-1" }, "locus": { "chromosome": "7", "start_pos": 81353935, "end_pos": 81313805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014753.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014753.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014753.5", "url": "https://www.ensembl.org/id/ENSBTAP00000014753.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:525155", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525155", "resource": "KEGG Pathway" }, { "id": "R-BTA-77289", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77289", "resource": "Reactome", "description": "Mitochondrial Fatty Acid Beta-Oxidation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NDD5-1", "protein_name": "Acetyl-coenzyme A thioesterase", "gene_name": "ACOT12", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERCGTAEGWVPMCQSVLPAHADHRGELNAGQLLKWMDATACLAAEKHAGVSCVTASMDDIQFEEAARVGQVITIKAKVNRAFKTSMEVGIKVTVQDVLTNVEKIVSVAYATYVVKPVGAKKIELEPVKLLSAEDHLEHALATERKRIRLGYQEVFQNLMQESNKEDDHYDTFEEQDAVSTDLTHVQSIELVQPPHANHHGNTFGGQIMAWMEAVARISASRLCRSYPNLKSVNMFKFWGPSVVGDRLVFNAVVNNTFQNSVEVGVRVEAYNCEEWIKNQARHINSAFLIFNSVNDKGELLTFPKIKPTTKDGVRRYHGAIARKRIRLARKYMLYAKEDKPYDLWEKSNQAYMSYSNIATLTYLAAKPGWEVTSTLNNIKIWTHEDGDVLSLKVEMQVKTASHVAFSLLSNFTYRQQWDKRFLTCEVLQAVSEDDKIYYITSPPPPMTGHQPRDFVILVSRRQPLEPSEPYIVAVKSVTLTSMPPSSEHCRSEILCAGFQIYSESSSSCRVYYFNQMTPDLIPYLAASLTGSLNSIEDTALECIKFLELKGSKC", "length": 554 }, "evidence": [ { "id": "E1BNW7", "url": "https://omabrowser.org/oma/group/E1BNW7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8WYK0-1", "protein_name": "Acetyl-coenzyme A thioesterase", "gene_name": "ACOT12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERPAPGEVVMSQAIQPAHATARGELSAGQLLKWIDTTACLAAEKHAGVSCVTASVDDIQFEETARVGQVITIKAKVTRAFSTSMEISIKVMVQDMLTGIEKLVSVAFSTFVAKPVGKEKIHLKPVTLLTEQDHVEHNLAAERRKVRLQHEDTFNNLMKESSKFDDLIFDEEEGAVSTRGTSVQSIELVLPPHANHHGNTFGGQIMAWMETVATISASRLCWAHPFLKSVDMFKFRGPSTVGDRLVFTAIVNNTFQTCVEVGVRVEAFDCQEWAEGRGRHINSAFLIYNAADDKENLITFPRIQPISKDDFRRYRGAIARKRIRLGRKYVISHKEEVPLCIHWDISKQASLSDSNVEALKKLAAKRGWEVTSTVEKIKIYTLEEHDVLSVWVEKHVGSPAHLAYRLLSDFTKRPLWDPHFVSCEVIDWVSEDDQLYHITCPILNDDKPKDLVVLVSRRKPLKDGNTYTVAVKSVILPSVPPSPQYIRSEIICAGFLIHAIDSNSCIVSYFNHMSASILPYFAGNLGGWSKSIEETAASCIQFLENPPDDGFVSTF", "length": 555 }, "evidence": [ { "id": "E1BNW7", "url": "https://omabrowser.org/oma/group/E1BNW7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99NB7-1", "protein_name": "Acetyl-coenzyme A thioesterase", "gene_name": "Acot12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPTVAPGEVLMSQAIQPAHADSRGELSAGQLLKWMDTTACLAAEKHAGISCVTASMDDILFEDTARIGQIVTIRAKVTRAFSTSMEISIKVRVQDKFTGIQKLLCVAFSTFVVKPLGKEKVHLKPVLLQTEQEQVEHRLASERRKVRLQHENTFSNIMKESNWLRDPVCNEEEGTATTMATSVQSIELVLPPHANHHGNTFGGQIMAWMETVATISASRLCHGHPFLKSVDMFKFRGPSTVGDRLVFNAIVNNTFQNSVEVGVRVEAFDCREWAEGQGRHINSAFLIYNAVDDQEELITFPRIQPISKDDFRRYQGAIARRRIRLGRKYVISHKKEVPLGTQWDISKKGSISNTNVEALKNLASKSGWEITTTLEKIKIYTLEEQDAISVKVEKQVGSPARVAYHLLSDFTKRPLWDPHYISCEVIDQVSEDDQIYYITCSVVNGDKPKDFVVLVSQRKPLKDDNTYIVALMSVVLPSVPPSPQYIRSQVICAGFLIQPVDSSSCTVAYLNQMSDSILPYFAGNIGGWSKSIEEAAASCIKFIENATHDGLKSVL", "length": 556 }, "evidence": [ { "id": "E1BNW7", "url": "https://omabrowser.org/oma/group/E1BNW7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DBK0-1", "protein_name": "Acetyl-coenzyme A thioesterase", "gene_name": "Acot12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESMVAPGEVLMSQAIQPAHADSRGELSAGQLLKWMDTTACLAAEKHAGISCVTASMDDILFEDTARIGQIITIRAKVTRAFSTSMEISIKVIVQDKFTGIQKLLCVAFSTFVAKPVGKEKVHLKPVLLQTEQEQVEHNLASERRKVRLQHENTFNNIMKESSRFSDSICNEEEGTATTMGTSVQSIELVLPPHANHHGNTFGGQIMAWMETVATISASRLCHGHPFLKSVDMFKFRGPSTVGDRLVFSAIVNNTFQNSVEVGVRVEAFDCQEWAEGQGRHINSAFLIYNAVDDQEKLITFPRIQPISKDDFRRYQGAIARRRIRLGRKYVISHKKEVPLSAQWDISKKGSLSNTNVEALKNLASKSGWEITTTLEKIKIYTLEEQDAISVKVEKLVGSPAHIAYHLLSDLTKRPLWDPHYISCEVIDQVSEDDQIYYITCSVVNGDKPKDFVVLVSRRKPLKDNNTYTVALRSVVLPSVPSSPQYIRSEVICAGFLIQAVDSNSCTVTYLNQMSDSILPYFAGNIGGWSKSIEEAAASCIKFIENATPDGLKSVL", "length": 556 }, "evidence": [ { "id": "E1BNW7", "url": "https://omabrowser.org/oma/group/E1BNW7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "acetyl-CoA hydrolase activity", "id": "GO:0003986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003986", "evidence": [ { "database": "UniProtKB", "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ], "pmid": "" }, { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ], "pmid": "" }, { "name": "acetyl-CoA metabolic process", "id": "GO:0006084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006084", "evidence": [ { "database": "UniProtKB", "id": "E1BNW7", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20289", "name": "", "equation": "acetyl-CoA + H2O = acetate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3T0R7-1", "E1BNW7-1", "F6RWU6-1" ], "evidence": [ { "id": "20289", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20289" } ] }, { "id": "40111", "name": "", "equation": "butanoyl-CoA + H2O = butanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M171-1", "E1BNW7-1", "Q3T0R7-1", "Q3SWX2-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "40111", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40111" } ] }, { "id": "40115", "name": "", "equation": "hexanoyl-CoA + H2O = hexanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3T0R7-1", "E1BNW7-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "40115", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40115" } ] }, { "id": "R-BTA-5690043", "name": "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6QGE6-1", "E1BNW7-1" ], "evidence": [ { "id": "R-BTA-5690043", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5690043" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M171", "gene_name": "ACOT11", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A3Q1M171", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M171" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A3Q1M171", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M171" } ] } ] }, { "uniprot_ac": "E1BNW7", "gene_name": "ACOT12", "activity": [ { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ] } ] }, { "uniprot_ac": "F6QGE6", "gene_name": "ACOT13", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "F6QGE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "F6QGE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ] } ] }, { "uniprot_ac": "F6RWU6", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] } ] }, { "uniprot_ac": "Q3SWX2", "gene_name": "ACOT9", "activity": [ { "ec_number": "3.1.2.-", "activity": "", "evidence": [ { "id": "Q3SWX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWX2" } ] }, { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "Q3SWX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWX2" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "Q3SWX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWX2" } ] } ] }, { "uniprot_ac": "Q3T0R7", "gene_name": "ACAA2", "activity": [ { "ec_number": "3.1.2.-", "activity": "", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] }, { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] }, { "ec_number": "2.3.1.9", "activity": "2 acetyl-CoA = acetoacetyl-CoA + CoA.", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNW7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 557, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNW7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNW7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" }, { "id": "PS51770", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51770" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HotDog ACOT-type", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 119, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" }, { "id": "PS50848", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50848" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "START", "eco_id": "ECO_0000259", "start_pos": 367, "end_pos": 557, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.2.1", "ec_name": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "3.1.2.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.1" }, { "id": "3.1.2.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.2.1" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 254, "end_pos": 256 }, { "start_pos": 411, "end_pos": 413 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNX0-1", "uniprot_ac": "E1BNX0", "uniprot_id": "E1BNX0_BOVIN", "mass": { "chemical_mass": 45600.0, "monoisotopic_mass": 45600.0 }, "refseq": {}, "gene_names": [ { "name": "ZACN", "type": "recommended", "evidence": [ { "id": "E1BNX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNX0" } ] } ], "protein_names": [ { "name": "Ligand-gated cation channel ZACN", "type": "recommended", "evidence": [ { "id": "E1BNX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNX0/entry#names_and_taxonomy" } ] }, { "name": "Zinc-activated channel", "type": "synonym", "evidence": [ { "id": "E1BNX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNX0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Ligand-gated cation channel that allows the movement of sodium and potassium monoatomic cations across cell membranes when activated by zinc (Zn2+), copper (Cu2+), and changes in pH. Could also transport cesium.", "evidence": [ { "database": "UniProtKB", "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0#function" }, { "database": "UniProtKB", "id": "ARBA00058416", "url": "https://www.uniprot.org/uniprotkb/ARBA00058416#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZACN", "url": "https://www.uniprot.org/uniprotkb/E1BNX0", "locus": { "chromosome": "19", "start_pos": 55578491, "end_pos": 55582905, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007906", "url": "https://www.ensembl.org/id/ENSBTAG00000007906" } ] } } ], "crossref": [ { "id": "E1BNX0", "url": "https://alphafold.ebi.ac.uk/entry/E1BNX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007906", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007906", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18994", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18994", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19065", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19065", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BNX0", "url": "https://www.orthodb.org/?gene=E1BNX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNX0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMALRLLLHLTFLGLGTTQPLAQQQGFSVPAFDWPSSSNLNSPQEVPDLIQIPNNGSKPLVVDVQVFVSNVFNVDILRYTVSSTLLLRLSWLNTRLALNSTGHQRNPVMLPWDVLWMPRLTVREALWVNWQDKSPQARVDRDGHIEFDLALTTETNCDFELFHFPRDQSDCHLTFFAFSNTVTELEFQVHAVNEIVSVKREFVVQDLKTQIPPQHLVPCFQVTLRLQNTALKAILTLLVPGEALLLADLCGGLLPLHTERIAYKVTLLLSYLVFHSSLIQALPSSSSCNPLLVYYFTVLLLLLFVSTTETVLLTGLLARGNLRAEDSPSPALNGEQHNRGKPGPNPEEAPGAGKGSRRSWAEAADRIFFQVYVVGVACSQFIFIALWMWATCKSDPAPGAASPHGGQPRL", "length": 410, "header": "tr|E1BNX0-1|E1BNX0_BOVIN Isoform 1 of Ligand-gated cation channel ZACN OS=Bos taurus OX=9913 GN=ZACN PE=3 SV=2 CANONICAL=E1BNX0-1" }, "isoforms": [ { "isoform_ac": "E1BNX0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNX0/entry#E1BNX0-1", "sequence": { "sequence": "MMALRLLLHLTFLGLGTTQPLAQQQGFSVPAFDWPSSSNLNSPQEVPDLIQIPNNGSKPLVVDVQVFVSNVFNVDILRYTVSSTLLLRLSWLNTRLALNSTGHQRNPVMLPWDVLWMPRLTVREALWVNWQDKSPQARVDRDGHIEFDLALTTETNCDFELFHFPRDQSDCHLTFFAFSNTVTELEFQVHAVNEIVSVKREFVVQDLKTQIPPQHLVPCFQVTLRLQNTALKAILTLLVPGEALLLADLCGGLLPLHTERIAYKVTLLLSYLVFHSSLIQALPSSSSCNPLLVYYFTVLLLLLFVSTTETVLLTGLLARGNLRAEDSPSPALNGEQHNRGKPGPNPEEAPGAGKGSRRSWAEAADRIFFQVYVVGVACSQFIFIALWMWATCKSDPAPGAASPHGGQPRL", "length": 410, "header": "tr|E1BNX0-1|E1BNX0_BOVIN Isoform 1 of Ligand-gated cation channel ZACN OS=Bos taurus OX=9913 GN=ZACN PE=3 SV=2 CANONICAL=E1BNX0-1" }, "locus": { "chromosome": "19", "start_pos": 55582706, "end_pos": 55579349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010396.6", "url": "https://www.ensembl.org/id/ENSBTAT00000010396.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010396.5", "url": "https://www.ensembl.org/id/ENSBTAP00000010396.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0" } ], "pmid": "" }, { "name": "extracellular ligand-gated monoatomic ion channel activity", "id": "GO:0005230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005230", "evidence": [ { "database": "UniProtKB", "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0" } ], "pmid": "" }, { "name": "ligand-gated monoatomic cation channel activity", "id": "GO:0099094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099094", "evidence": [ { "database": "UniProtKB", "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0" } ], "pmid": "" }, { "name": "pH-gated monoatomic ion channel activity", "id": "GO:0160128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160128", "evidence": [ { "database": "UniProtKB", "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0" } ], "pmid": "" }, { "name": "transmembrane transporter complex", "id": "GO:1902495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902495", "evidence": [ { "database": "UniProtKB", "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to zinc ion", "id": "GO:0010043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010043", "evidence": [ { "database": "UniProtKB", "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "E1BNX0", "url": "https://www.uniprot.org/uniprotkb/E1BNX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35526-1" ], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35526-1" ], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNX0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 410, "overlap": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNX2-1", "uniprot_ac": "E1BNX2", "uniprot_id": "E1BNX2_BOVIN", "mass": { "chemical_mass": 80545.0, "monoisotopic_mass": 80545.0 }, "refseq": {}, "gene_names": [ { "name": "GPR149", "type": "recommended", "evidence": [ { "id": "E1BNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNX2" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 149", "type": "synonym", "evidence": [ { "id": "E1BNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNX2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNX2", "url": "https://www.uniprot.org/uniprotkb/E1BNX2" } ], "common_name": "Bovine", "glygen_name": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNX6" } ] }, { "name": "SGMS2", "type": "synonym", "evidence": [ { "id": "NP_001192806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192806" } ] } ], "protein_names": [ { "name": "Sphingomyelin synthase 2", "type": "synonym", "evidence": [ { "id": "E1BNX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNX6/entry#names_and_taxonomy" } ] }, { "name": "phosphatidylcholine:ceramide cholinephosphotransferase 2", "type": "synonym", "evidence": [ { "id": "NP_001192806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192806" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNX6", "url": "https://www.uniprot.org/uniprotkb/E1BNX6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SGMS2", "url": "https://www.uniprot.org/uniprotkb/E1BNX6", "locus": { "chromosome": "6", "start_pos": 17297003, "end_pos": 17318378, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016805", "url": "https://www.ensembl.org/id/ENSBTAG00000016805" } ] } } ], "crossref": [ { "id": "E1BNX6", "url": "https://alphafold.ebi.ac.uk/entry/E1BNX6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016805", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016805", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01610", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01610", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "520954", "url": "https://www.ncbi.nlm.nih.gov/gene/520954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:520954", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520954", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SKFPLEW", "url": "https://omabrowser.org/oma/group/SKFPLEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNX6", "url": "https://www.orthodb.org/?gene=E1BNX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21290:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21290:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14360", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14360", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1660661", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1660661", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192806", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192806", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36079", "url": "https://www.rhea-db.org/rhea/36079", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BNX6", "url": "https://www.uniprot.org/uniprotkb/E1BNX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNX6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIIETAKLEEHMENQTNDPANTYTRPPEPVEEENKNGNSKPKSLSNGLRKSTKKYPDYIQIAMPTEARNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTVDVIVAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365, "header": "tr|E1BNX6-1|E1BNX6_BOVIN Isoform 1 of Sphingomyelin synthase 2 OS=Bos taurus OX=9913 GN=SGMS2 PE=3 SV=1 CANONICAL=E1BNX6-1" }, "isoforms": [ { "isoform_ac": "E1BNX6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNX6/entry#E1BNX6-1", "sequence": { "sequence": "MDIIETAKLEEHMENQTNDPANTYTRPPEPVEEENKNGNSKPKSLSNGLRKSTKKYPDYIQIAMPTEARNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTVDVIVAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365, "header": "tr|E1BNX6-1|E1BNX6_BOVIN Isoform 1 of Sphingomyelin synthase 2 OS=Bos taurus OX=9913 GN=SGMS2 PE=3 SV=1 CANONICAL=E1BNX6-1" }, "locus": { "chromosome": "6", "start_pos": 17318179, "end_pos": 17297420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022353.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022353.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022353.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022353.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:520954", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520954", "resource": "KEGG Pathway" }, { "id": "R-BTA-1660661", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1660661", "resource": "Reactome", "description": "Sphingolipid de novo biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NT99-1", "protein_name": "2.7.8.27", "gene_name": "sgms2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASSDHQGNKEPTNTSRTDGAPSTGATCPVHSAEDAKRNGLRKGLVRHRDYVKISVPEGKGNRLPSEWWKTFIALFYAALNLVLTTVMITVVHERVPPKEESPPLPDKFFDYIDRVQWAFTVTEVNGMVLVSIWGIQLLFHRYKAIVARRYFFLLGTLYMYRCITMYVTTLPVPGMHMVCAPKLHGDSEAKLQRVLQLLSGGGLSINGSHLLCGDFLYSGHTVILTLTYLFLKEYSPRSFWWYHLLCWLTAAVGVVCILVAHEHYSVDVVVAYFITTRLFYWYHTMANLQTLKCSPNNYLTHTWWNPVFNLFERNVQTHVPCSFCWPITWPPACLKNPCKKYSMVQSGREE", "length": 351 }, "evidence": [ { "id": "E1BNX6", "url": "https://omabrowser.org/oma/group/E1BNX6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1NLG9-1", "protein_name": "Sphingomyelin synthase 2", "gene_name": "SGMS2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNTIETAKLEDHMEGQNNDTANGYTRPTLSVSEENKNGNNKPKGLSNGLRKTAKKYPDYIQIAMPAESRNKFPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKERSPPLPDKFFDYIDRVTWAFSVSEINGMILVGLWIFQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLIYLFIKEYSPRHFWWYHLICWLMSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKTLKVSSQTNFLSRAWWYPIFYFFEKNVQGSVPCSFSWPISWPPSCFKSSCKKYSRVQKTGEDNEKST", "length": 365 }, "evidence": [ { "id": "E1BNX6", "url": "https://omabrowser.org/oma/group/E1BNX6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S122-1", "protein_name": "Sphingomyelin synthase 2", "gene_name": "SGMS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDIIETAKLEEHMENQTSEPANTYARPAEPIEEENKNGNGKPKSLSNGLRKGTKKYPDYIQIAMPTDSRNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTVDVIVAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "E1BNX6", "url": "https://omabrowser.org/oma/group/E1BNX6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I338-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2 isoform X1", "gene_name": "Sgms2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDIIETAKLEGHLENQTNDSTNTYTGPADTVEEGNKNGNGKPKSLSNGLRKGAKKYPDYIQISMPTDSRNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYVDRVKWAFSVSEINGIVLVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "E1BNX6", "url": "https://omabrowser.org/oma/group/E1BNX6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4JM44-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "gene_name": "Sgms2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDIIETAKLEGHLESQTNNSTNTYTSPTEAVEEEDKNGKGKPKTLSNGLRKGAKKYPDYIQISMPNDSRNKLPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKELSPPLPDKFFDYVDRVKWAFSVSEINGMVLVGLWLTQWLFLRYKSIVGRRFFFIMGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLLSGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "E1BNX6", "url": "https://omabrowser.org/oma/group/E1BNX6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NHU3-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "gene_name": "SGMS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDIIETAKLEEHLENQPSDPTNTYARPAEPVEEENKNGNGKPKSLSSGLRKGTKKYPDYIQIAMPTESRNKFPLEWWKTGIAFIYAVFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFCFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVTLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTIDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "E1BNX6", "url": "https://omabrowser.org/oma/group/E1BNX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4B1-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "gene_name": "Sgms2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDIIETAKLEGHLESQTNDSTNTYTSPTEAVEEEGKNGKGKPKTLSNGLRKGAKKYPDYIQISMPNDSKNKFPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKELSPPLPDKFFDYFDRVKWAFSVSEINGMVLVGLWITQWLFLRYKSIVGRRFFFIMGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCRKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "E1BNX6", "url": "https://omabrowser.org/oma/group/E1BNX6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sphingomyelin biosynthetic process", "id": "GO:0006686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006686", "evidence": [ { "database": "UniProtKB", "id": "E1BNX6", "url": "https://www.uniprot.org/uniprotkb/E1BNX6" } ], "pmid": "" }, { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "E1BNX6", "url": "https://www.uniprot.org/uniprotkb/E1BNX6" } ], "pmid": "" }, { "name": "regulation of bone mineralization", "id": "GO:0030500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030500", "evidence": [ { "database": "UniProtKB", "id": "E1BNX6", "url": "https://www.uniprot.org/uniprotkb/E1BNX6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ceramide phosphoethanolamine synthase activity", "id": "GO:0002950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002950", "evidence": [ { "database": "UniProtKB", "id": "E1BNX6", "url": "https://www.uniprot.org/uniprotkb/E1BNX6" } ], "pmid": "" }, { "name": "sphingomyelin synthase activity", "id": "GO:0033188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033188", "evidence": [ { "database": "UniProtKB", "id": "E1BNX6", "url": "https://www.uniprot.org/uniprotkb/E1BNX6" } ], "pmid": "" }, { "name": "ceramide cholinephosphotransferase activity", "id": "GO:0047493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047493", "evidence": [ { "database": "UniProtKB", "id": "E1BNX6", "url": "https://www.uniprot.org/uniprotkb/E1BNX6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BNX6", "url": "https://www.uniprot.org/uniprotkb/E1BNX6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BNX6", "url": "https://www.uniprot.org/uniprotkb/E1BNX6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BNX6", "url": "https://www.uniprot.org/uniprotkb/E1BNX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36079", "name": "", "equation": "an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphing-4-enine 1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M660-1", "F1MYS1-1" ], "evidence": [ { "id": "36079", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36079" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M660", "gene_name": "SGMS1", "activity": [ { "ec_number": "2.7.8.27", "activity": "an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol.", "evidence": [ { "id": "A0A3Q1M660", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M660" } ] }, { "ec_number": "2.7.8.27", "activity": "", "evidence": [ { "id": "A0A3Q1M660", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M660" } ] } ] }, { "uniprot_ac": "F1MYS1", "gene_name": "SAMD8", "activity": [ { "ec_number": "3.1.4.62", "activity": "a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = phosphoethanolamine + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "F1MYS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYS1" } ] }, { "ec_number": "3.1.4.62", "activity": "", "evidence": [ { "id": "F1MYS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYS1" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNX6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 365, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNX6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNX6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNY6-1", "uniprot_ac": "E1BNY6", "uniprot_id": "E1BNY6_BOVIN", "mass": { "chemical_mass": 44851.0, "monoisotopic_mass": 44851.0 }, "refseq": { "ac": "NP_001179261", "name": "solute carrier family 35 member D3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179261" }, "gene_names": [ { "name": "SLC35D3", "type": "recommended", "evidence": [ { "id": "E1BNY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ] }, { "name": "SLC35D3", "type": "synonym", "evidence": [ { "id": "NP_001179261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179261" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member D3", "type": "synonym", "evidence": [ { "id": "E1BNY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY6/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 35 member D3", "type": "synonym", "evidence": [ { "id": "NP_001179261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179261" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC35D3", "url": "https://www.uniprot.org/uniprotkb/E1BNY6", "locus": { "chromosome": "9", "start_pos": 74892825, "end_pos": 74889357, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016793", "url": "https://www.ensembl.org/id/ENSBTAG00000016793" } ] } } ], "crossref": [ { "id": "E1BNY6", "url": "https://alphafold.ebi.ac.uk/entry/E1BNY6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016793", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016793", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539925", "url": "https://www.ncbi.nlm.nih.gov/gene/539925", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR050186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539925", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539925", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GWKDPTM", "url": "https://omabrowser.org/oma/group/GWKDPTM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNY6", "url": "https://www.orthodb.org/?gene=E1BNY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001179261", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179261", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNY6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNY6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQLCRRGRVLGIAVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGFIAVPPFGLNLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVVLSFASTDSIHAWTFPGWKDPAMVTIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCAAKFLETRKQINYEDLETQPGGEEAQPSGDQLPFVMEELPAEGGNGWSEGGKAAGGSTQRDGQEARGSPRGVSLMARSSQISDSPEEVGRSSLKDAYLEVWRLVRGAKYVKKDYLIDNEELPSP", "length": 423, "header": "tr|E1BNY6-1|E1BNY6_BOVIN Isoform 1 of Solute carrier family 35 member D3 OS=Bos taurus OX=9913 GN=SLC35D3 PE=4 SV=1 CANONICAL=E1BNY6-1" }, "isoforms": [ { "isoform_ac": "E1BNY6-1", "url": "https://www.uniprot.org/uniprotkb/E1BNY6/entry#E1BNY6-1", "sequence": { "sequence": "MRQLCRRGRVLGIAVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGFIAVPPFGLNLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVVLSFASTDSIHAWTFPGWKDPAMVTIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCAAKFLETRKQINYEDLETQPGGEEAQPSGDQLPFVMEELPAEGGNGWSEGGKAAGGSTQRDGQEARGSPRGVSLMARSSQISDSPEEVGRSSLKDAYLEVWRLVRGAKYVKKDYLIDNEELPSP", "length": 423, "header": "tr|E1BNY6-1|E1BNY6_BOVIN Isoform 1 of Solute carrier family 35 member D3 OS=Bos taurus OX=9913 GN=SLC35D3 PE=4 SV=1 CANONICAL=E1BNY6-1" }, "locus": { "chromosome": "9", "start_pos": 74891821, "end_pos": 74889556, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022340.4", "url": "https://www.ensembl.org/id/ENSBTAT00000022340.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022340.2", "url": "https://www.ensembl.org/id/ENSBTAP00000022340.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539925", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539925", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XMV3-1", "protein_name": "Solute carrier family 35 member D3", "gene_name": "SLC35D3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVRWRGRARGVAVAVAHGLCSGSLNILLKFLLARYHFAFLTLLQCLSSAAAALGLEALRRRGLAALPPFGLRLARPFAAVAALATLQSTLTLWSLRGLSLPMYVVFKRCLPLVTLLTGALVLRDGMPSPGVLVAVLITTCGAALAGAGDLTGDAMGYVTGVLAVLIHAAYLVLIQKTSVDSEYGPLTAQYAIAVSATPFLIICSFASMDSINVWSFPGWKDPAMVCIFIACVLISCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFNDVEPTKLFIAGVVVNTLGSVIYCVAKYIETRQQSTYEDLEKEGREEEGKRQAGDQALFAMEAISPEKGAREAAVEGSAEGDSQGGEDEKDSAKKAAGEPSAQGKATSTQDGSRSSLKDAYLGVWRLVRGANYIKKDYLIENEELPSP", "length": 421 }, "evidence": [ { "id": "E1BNY6", "url": "https://omabrowser.org/oma/group/E1BNY6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A5L7-1", "protein_name": "Solute carrier family 35, member D3", "gene_name": "Slc35d3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRQLCRGRVLGISVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGLIAVPPFGLSLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVICSFASTDSIHAWTFPGWKDPAMVSIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCVAKFLETRRQSNYEDLESQAEGEESQPSGDQLPFVMEELPAEGGNSEPESAEGAGDSVEQGGQESRGSPRGVSLVARRAEGHSEEGSRRSLKDTYLEVWRLVRGTKYMKKDYLIENEALPSP", "length": 420 }, "evidence": [ { "id": "E1BNY6", "url": "https://omabrowser.org/oma/group/E1BNY6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S688-1", "protein_name": "Solute carrier family 35 member D3", "gene_name": "SLC35D3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQQLCRGRVLGITVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGFIAVPPFGLSLARSFAGVTVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGVPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVICSFASTDSIHAWTFPGWKDPAMVCIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCVAKYLETRKQSNYEDLETQPGGEEAQPSGDQLPFVMEELPAAEGGSGGSGGGKAAGGSTQQGGQEARGSPRGAPLAARSSQVSDSPEEMSRRSLKDAYLEVWRLVRGTKYMKKDYLIENEELPSP", "length": 423 }, "evidence": [ { "id": "E1BNY6", "url": "https://omabrowser.org/oma/group/E1BNY6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5M8T2-1", "protein_name": "Solute carrier family 35 member D3", "gene_name": "SLC35D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRQLCRGRVLGISVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGLIAVPPFGLSLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVICSFASTDSIHAWTFPGWKDPAMVCIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCVAKFMETRKQSNYEDLEAQPRGEEAQLSGDQLPFVMEELPGEGGNGRSEGGEAAGGPAQESRQEVRGSPRGVPLVAGSSEEGSRRSLKDAYLEVWRLVRGTRYMKKDYLIENEELPSP", "length": 416 }, "evidence": [ { "id": "E1BNY6", "url": "https://omabrowser.org/oma/group/E1BNY6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BGF8-1", "protein_name": "Solute carrier family 35 member D3", "gene_name": "Slc35d3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRQLCRGRVLGISVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGLIAVPPFGLSLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVICSFASTDSIHAWTFPGWKDPAMVSIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCVAKFLETRRQSNYEDLESQAEGEERQPSGDQLPFVMEELPAKSGNSEPESAEGAGDSVQQGGQESRGSIRGISLAARSSRAEGHSDEVGRRSLKDTYLEVWRLVRGTKYMKKDYLMENEALPSP", "length": 422 }, "evidence": [ { "id": "E1BNY6", "url": "https://omabrowser.org/oma/group/E1BNY6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94B65-1", "protein_name": "UDP-galactose/UDP-glucose transporter 7", "gene_name": "UTR7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVQAEMEPTSSISLVAAVSYGIASMAMVFINKAVIMQYPHSMTVLTLQQLATSLLIHFGRRMGYTRAKGIDMATAKKLLPVSIFYNANVAFALASLKGVNIPMYIAIKRLTPLAVLISGVLFGKGKPTTQVALSVLLTAAGCVIAALGDFSFDLFGYGLALTSVFFQTMYLVLVEKSGAEDGLSSIEIMFYNSFLSLPFLSILIIVTGEFPNSLSLLLAKCSYLPFLVILILSLVMGIVLNFTMFLCTIVNSALTTTIVGVLKGVGSTTLGFVLLGGVEVHALNVSGLVVNTAGGVWYSYAKYRQKKAKPAKLMSDLEAHKK", "length": 323 }, "evidence": [ { "id": "E1BNY6", "url": "https://omabrowser.org/oma/group/E1BNY6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ], "pmid": "" }, { "name": "UDP-glucose transmembrane transporter activity", "id": "GO:0005460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005460", "evidence": [ { "database": "UniProtKB", "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ], "pmid": "" }, { "name": "platelet dense granule organization", "id": "GO:0060155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060155", "evidence": [ { "database": "UniProtKB", "id": "E1BNY6", "url": "https://www.uniprot.org/uniprotkb/E1BNY6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNY6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 423, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNY6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNY6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 241, "end_pos": 243 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BNY8-1", "uniprot_ac": "E1BNY8", "uniprot_id": "E1BNY8_BOVIN", "mass": { "chemical_mass": 236187.0, "monoisotopic_mass": 236187.0 }, "refseq": { "ac": "NP_001180170", "name": "general transcription factor 3C polypeptide 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180170" }, "gene_names": [ { "name": "GTF3C1", "type": "recommended", "evidence": [ { "id": "E1BNY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY8" } ] }, { "name": "GTF3C1", "type": "synonym", "evidence": [ { "id": "NP_001180170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180170" } ] } ], "protein_names": [ { "name": "Ral transcription factor IIIC subunit 1", "type": "synonym", "evidence": [ { "id": "E1BNY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY8/entry#names_and_taxonomy" } ] }, { "name": "general transcription factor 3C polypeptide 1", "type": "synonym", "evidence": [ { "id": "NP_001180170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180170" } ] }, { "name": "general transcription factor IIIC, polypeptide 1, alpha 220kDa", "type": "synonym", "evidence": [ { "id": "NP_001180170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180170" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNY8", "url": "https://www.uniprot.org/uniprotkb/E1BNY8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GTF3C1", "url": "https://www.uniprot.org/uniprotkb/E1BNY8", "locus": { "chromosome": "25", "start_pos": 25009630, "end_pos": 25089814, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006126", "url": "https://www.ensembl.org/id/ENSBTAG00000006126" } ] } } ], "crossref": [ { "id": "ENSBTAG00000006126", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006126", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16169", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16169", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "509874", "url": "https://www.ncbi.nlm.nih.gov/gene/509874", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509874", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509874", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TIIQDGI", "url": "https://omabrowser.org/oma/group/TIIQDGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNY8", "url": "https://www.orthodb.org/?gene=E1BNY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15180", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15180", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15180:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15180:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04182", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04182", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24101", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24101", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-76061", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76061", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-76066", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001180170", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180170", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BNY8", "url": "https://www.uniprot.org/uniprotkb/E1BNY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNY8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDALESLLDEVALEGLDGLCLPALWSRLETRVPPFPLPLEPYTQEFLWRALATNPGISFYEEPRERPDLQLQDRYEEIDLETGIVESRRDPVPLEDVYPIHMILENKDGIQGSCRYFKERKNITNDIRTKMLQPRCTMVEAFGRWGKKLIIVASQDMRYRALIGFEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHSTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHMDRRSKYDILMEKLSTLLSARNNRTETLGKLREELGLCERTFKRLYQYMLNAGLAKVVPLPLKEIHPERGPCKTKKGTDIMVRCLRLLKEFKRKVDDDDDDEDVISKGVPPVDIVFERDMLTQTYELIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYEREKARNELLTTVSLASVQEESLLPEGEDAFLSELDSDEEGGGGGRKRKGRRAPRDARSFSNGGLRTQPHHSTPNKGGWKVINLHPLKKQPSFSPGAAEERASRGAFGGDNLDTSGSSELGMSLGPHCVDSHGGDIAVIEEVRLENSKDSGGSQKTGKHGPGQDKPHETYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIIRLVQNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRMSNSSTANRMKAPQPPVPQEEAEEESQGEEGPSGSGDAQPSASSKPEGGRVKKTHEKMGVTQLKNYHPVVVPGLGRSLGFLPKMPRLRVIHMFLWYLIYGHPTTVEELSFSERKAGVPSSSRSDLEASFDAAPKDTWEGEVELATETVFVDEASWKRYVPPIPVHKDFGFGWALVSDLLLCLPLSIFTQVVQVSYKVDHLEEFLNDPLKKHTLIRFLPRSIRQQLLYKRRFIFSVVENLQRLCFMGLLQFGPTEKFQDKDQVFVYLKKNVGVVDTTTCDPHYNVARSSRPFERRSYVLNSVQDVENYWFDLQCVCLNTPLGVVRCPRARKSSGPDQGSDEEGRMQKEQENAMDKYTLERKCAMMEYTMGSREVVDEGIIPGDGLGAAGLDSSFYAHLKRNWIWTSYIMDKAKKETTTSENGLTMRLQTFLSKRPMPLGAGGNGRLTVWGDARAGSGLCADRDEHIEVEREPTLERNQKVKGGKSQKRKRLKKDPGKKIKRKKKEELPEDKNKRRYHDEADQSALQRMTRLRVTWSLQEDGLLMLCRIASNVLNTKVKGPFVPWQVVRDILHSTLEESLDKTSLSVGRRARYIIKNPQAYLNYKVCLAEVYQDKALVGEFLSRKGDYGNPKVCASEFKEFVAKLREKFSSALKNPNLEIPDTLEELFARYRVLVIGDKKDQVMKEDELKSVDDIHFLVLQNLIQSTLALSDRQMEICQSFQTFRLYRDYKEQVLVKAFVDYQRRSLVNRRRVNHTLGPKKNRALPFAPMSYQLSQAYHRIFTWRFPSTVCTESFQFFSRLLAAGKRDQADHFSFKDQNCGEPASDLVAFSLDGPGGNCVTALILFSLGLVSVDVRIPEQIVVVDSSMVENEVIKSLGKDSTLEEDEDEEEDLDEGSGAKRRSIEVKAHQASHTNYLLMKGYCVPGIVSNRNLNPNDNIVVNSCLVKFRLRCTPKPTRLALTDPSLEELTVGPSCLPDTFTRLINSPEDTCSLEEFVHQVALSGYQPGDVFAALEIQEAIAAAGCFGVDRLELSKQFFALARTDSERTRTFTDYVQDLLEHQQVLEVGGNTARLVTMANAQPWLLHSVRLKDKDGGADLQRDDHRAKPPEGPSNEDNPPERQAPPSQSPQSTKRRGSWAGADTNSQGGAADPKSALEPPAKRPALQDIRLAPSPGPRAEEELGTLAPALLAAPEDGGASEAGPGDQEGVEVPSFPGQEQLSCQAQLPEAPEDPRGLADGSVAGNLSQVAWERDCESVRFIGRPWRIVDGRLNTPVVKGMMEAVLHHIMTRPGVPESCLLQHYKGVLQPLAVLELLQGLETLGCIKKCVLRKPAAASLFSKPPVGEAPLSLDESPVVFYEPTLDCTIRLGRVFPNEVSWNKWVHL", "length": 2096, "header": "tr|E1BNY8-1|E1BNY8_BOVIN Isoform 1 of Ral transcription factor IIIC subunit 1 OS=Bos taurus OX=9913 GN=GTF3C1 PE=4 SV=3 CANONICAL=E1BNY8-1" }, "isoforms": [ { "isoform_ac": "E1BNY8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNY8/entry#E1BNY8-1", "sequence": { "sequence": "MDALESLLDEVALEGLDGLCLPALWSRLETRVPPFPLPLEPYTQEFLWRALATNPGISFYEEPRERPDLQLQDRYEEIDLETGIVESRRDPVPLEDVYPIHMILENKDGIQGSCRYFKERKNITNDIRTKMLQPRCTMVEAFGRWGKKLIIVASQDMRYRALIGFEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHSTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHMDRRSKYDILMEKLSTLLSARNNRTETLGKLREELGLCERTFKRLYQYMLNAGLAKVVPLPLKEIHPERGPCKTKKGTDIMVRCLRLLKEFKRKVDDDDDDEDVISKGVPPVDIVFERDMLTQTYELIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYEREKARNELLTTVSLASVQEESLLPEGEDAFLSELDSDEEGGGGGRKRKGRRAPRDARSFSNGGLRTQPHHSTPNKGGWKVINLHPLKKQPSFSPGAAEERASRGAFGGDNLDTSGSSELGMSLGPHCVDSHGGDIAVIEEVRLENSKDSGGSQKTGKHGPGQDKPHETYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIIRLVQNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRMSNSSTANRMKAPQPPVPQEEAEEESQGEEGPSGSGDAQPSASSKPEGGRVKKTHEKMGVTQLKNYHPVVVPGLGRSLGFLPKMPRLRVIHMFLWYLIYGHPTTVEELSFSERKAGVPSSSRSDLEASFDAAPKDTWEGEVELATETVFVDEASWKRYVPPIPVHKDFGFGWALVSDLLLCLPLSIFTQVVQVSYKVDHLEEFLNDPLKKHTLIRFLPRSIRQQLLYKRRFIFSVVENLQRLCFMGLLQFGPTEKFQDKDQVFVYLKKNVGVVDTTTCDPHYNVARSSRPFERRSYVLNSVQDVENYWFDLQCVCLNTPLGVVRCPRARKSSGPDQGSDEEGRMQKEQENAMDKYTLERKCAMMEYTMGSREVVDEGIIPGDGLGAAGLDSSFYAHLKRNWIWTSYIMDKAKKETTTSENGLTMRLQTFLSKRPMPLGAGGNGRLTVWGDARAGSGLCADRDEHIEVEREPTLERNQKVKGGKSQKRKRLKKDPGKKIKRKKKEELPEDKNKRRYHDEADQSALQRMTRLRVTWSLQEDGLLMLCRIASNVLNTKVKGPFVPWQVVRDILHSTLEESLDKTSLSVGRRARYIIKNPQAYLNYKVCLAEVYQDKALVGEFLSRKGDYGNPKVCASEFKEFVAKLREKFSSALKNPNLEIPDTLEELFARYRVLVIGDKKDQVMKEDELKSVDDIHFLVLQNLIQSTLALSDRQMEICQSFQTFRLYRDYKEQVLVKAFVDYQRRSLVNRRRVNHTLGPKKNRALPFAPMSYQLSQAYHRIFTWRFPSTVCTESFQFFSRLLAAGKRDQADHFSFKDQNCGEPASDLVAFSLDGPGGNCVTALILFSLGLVSVDVRIPEQIVVVDSSMVENEVIKSLGKDSTLEEDEDEEEDLDEGSGAKRRSIEVKAHQASHTNYLLMKGYCVPGIVSNRNLNPNDNIVVNSCLVKFRLRCTPKPTRLALTDPSLEELTVGPSCLPDTFTRLINSPEDTCSLEEFVHQVALSGYQPGDVFAALEIQEAIAAAGCFGVDRLELSKQFFALARTDSERTRTFTDYVQDLLEHQQVLEVGGNTARLVTMANAQPWLLHSVRLKDKDGGADLQRDDHRAKPPEGPSNEDNPPERQAPPSQSPQSTKRRGSWAGADTNSQGGAADPKSALEPPAKRPALQDIRLAPSPGPRAEEELGTLAPALLAAPEDGGASEAGPGDQEGVEVPSFPGQEQLSCQAQLPEAPEDPRGLADGSVAGNLSQVAWERDCESVRFIGRPWRIVDGRLNTPVVKGMMEAVLHHIMTRPGVPESCLLQHYKGVLQPLAVLELLQGLETLGCIKKCVLRKPAAASLFSKPPVGEAPLSLDESPVVFYEPTLDCTIRLGRVFPNEVSWNKWVHL", "length": 2096, "header": "tr|E1BNY8-1|E1BNY8_BOVIN Isoform 1 of Ral transcription factor IIIC subunit 1 OS=Bos taurus OX=9913 GN=GTF3C1 PE=4 SV=3 CANONICAL=E1BNY8-1" }, "locus": { "chromosome": "25", "start_pos": 25089791, "end_pos": 25010459, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008061.6", "url": "https://www.ensembl.org/id/ENSBTAT00000008061.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008061.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008061.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509874", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509874", "resource": "KEGG Pathway" }, { "id": "R-BTA-76061", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76061", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 1 Promoter" }, { "id": "R-BTA-76066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76066", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 2 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZA51-1", "protein_name": "Ral transcription factor IIIC subunit 1", "gene_name": "GTF3C1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEALWALLDEVSLEGLDGITLGALWQRLAARTPPFPLPLEPATRQLLWAALSAQPDLRFYLLPRARPPLRLHDRYEEIDLETGILETKRDPLPLDDIYPVHMILDDKDGLQGSCQYFKERVDITDQIRRKDLQPCCTYTEAVEKWGEKLVIVASQDQRYRALIGWEGDPDLKLPDFSYCILERLGRARWQGELQRDLHSGAFKVDAGKIHYHRRVLDRNGLITMQSHVIRLPSGAQQHSILLLLTRFHVDRRSKYDILMEKLSSMLSARPNQIETLGNLREELGLCERTFKRLYQYMMNAGLAKVISIPLQEIQPNGGPYKTKKGTDVMVRCLKLLKEFRKKMEDYHDDDEEEITKVVQPVDIVCERDMLTQAYELIESRGTKGISQAELRLAMNVGKLESRMLCRLLERYKVVKGFMEDEGRQRTTKYISYIFAEESDLNRQFEREKARSEQLATVTLALVPEDSPPLEDAFPGEEDALVSESDNEEEVKYGKKRRKGQKASSGSLLKLSSQDAVHQSTPAKGSKPTAVKSLGKKLPSPPILEEPDEVPDNFSGESSTLETVKQESSLSTCPLIADEDGDMAVIEEVRLEDPKMCDQKKEKRSRAAAAERSRETYRLLKRRNLIVEAVRNLRLIESLFTLQKMVMDQEKQEGVSTKCCKKSIIRLVQKLSQEGLLRIYRTTVIQDGISKKVEFVVHPSVSPSDPLVRSAIEQVRFRISNSSTASRVKVPQTPSSQDHGEEENLGQEAFPESGDTQEGSSKDENNSRADKTDEKMGVTQLKNYHPVTVPGLGRFLGFLPKMPRLRIVHMFLWYLIYGHPLNGTDRKRSGDGKKKGSKQRPSVNEAQADGTIQVMKTVTNPEIAAQDSEVELSNQTVYVDDTSWMRYVPPLPVHREFGFGWALVSDILLCLPLSLFVQIVQVSYKVDGLEDFLNDPVKKHTLIRFLPRSVRQQLLYKRRYIFSVVENLQRLCYMGLIQFGPTEKFQEKDQVFVYMKRNAVIVDTTICDPHYNLAQSSRPFERRLYVLNTMQDVENFWFDLQCVCLNTPLGVVRCPRSKKSNPQEEEAALAMEQQSAVDKHNLERKCAMLEYTTGSREVVDDGTIPGDGLGAAGLDSSFYGHLKRNWIWTSYIINKTKKENTVSENRLTVRLQTFLTKHPLPLSTGGNKINILGEPKAGPESVIQKKESIEISQEATQDRNKRVRGGKNQKRKRLRKDTGKPTKKKKKEEKSVEKSKRLRYHDEADQSALQRMTRLRVTWTVQEDVLLMLCRIASHVLNAKVKGPFVPWQVVRDIMHASFEESLDKTSHSVGRRARYIVRNPQTYLNYKVCLAEVYQDKALIDEFMNRENNYEEPQVCAAEFKQFVERLKAKFSSTLGNPKLEIPDTLQELFARFRVMAIGEDTNHTTKEDSLNSVYDIHFLVLQNLIQSTLALSDNQMKSCQSFQTFRLYREYRDDILVKAFLECQKRSLVNRRRVNHTLGPKKSRALPFVAMSYQLSQSYYRVFTWRFPSTICTESFQFLQKLKDIGKSDQPDSFLFKDQESKASEGMITFPMDGPGGHCVAMLSLFSLGLVSVNVRIPEQIVVVDSTMVENEVIKSLGKDGLEEEEEEEDDLDDSSGGKRRIEVKARQASHTNYLLMRGYYAPGIVSTRNLSPSDNIVVNSCQVKVKLRCTPLPGRLSSPVSSQLDNMAVGVSSLPKTFTRLIKIQEENYNVDQFLRECTECYGYNPRDVAAVLEIRNAIEAASHFGVCKAELGKQFCSYEEEEPARTRNLQQYIQDLIEMQQVLEVGGNSIRLVAVVFAKPWLLHSVCPMNKPEDSGQQCADTAFPEAQQDCLLSAAKKGEECSGEEEQLGEDTNHPSDEEPPRKRCRTQNDGLQDGDQLCQGLQSGLLSANESHLDADITDPVTMKESFIPDGEMGSLGGTKHTAEGPSDVVSVDVPKDQDKPCSEDKQLEAGNDDLSPEHKHILSLEHSATEQHDDVSHLQENPEVSKGSSVPGLSQAAADGACENVCFIGRPWRIVDGNLNKPVCKGMMEAVLYHIMTKPGITEGMLLQHYTGTLQPVAVLEILQGLEALGCIRRFHMKAAPAVSLFSQPLIAEQLHSPRLSEASAAYYEPTMDCTLRLGGVFPTEVNWNKWVQVIHV", "length": 2143 }, "evidence": [ { "id": "E1BNY8", "url": "https://omabrowser.org/oma/group/E1BNY8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RFG1-1", "protein_name": "Ral transcription factor IIIC subunit 1", "gene_name": "GTF3C1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDALESLLDEVALEGLDGLCLPALWSRLETRVPPFPLPLEPYTQEFLWQALATHPGISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVSLEDVYPIHMILENKDGIQGSCRYFKERKNITKEIRTKALQPRCTMVEAFGRWGKKLIIVASQDMRYRALIGLEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHSTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGTQQHSILLLLNRFHMDRRSKYDILMEKLSGMLSTRSNHIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLPLQEIHPERGPCKTKKGTDVMVRCLRLLKEFKRKVEDDQDDDEDEEAISKVVPPVDIVYERDMLTQTYELIERRGTKGISQAEVRVAMNVGKLEARMLCRLLQRFKIVKGFMEDEGRQRTTKYISCVFAEESDLSRQYEREKARSELLATVSLASVQEESLLPEAEDAFLSESDSEEEGGRGRGRRRGRGSQADGRSSASGGLGPHSHHSTPTKGGWSVVSLHPLRKQPSSSPGAAEERACRSSAARDSLLDPSSSSDPSVSFGSHCVESHRGDIAVIEEVRLENPKESGGSQKAGKHGPGQDKPHETYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIVRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKMSQPPAPQGDPEEGSQGGKGPSGSGDCQPNASSTLEGGRVKKSDKKMNVPHLKNYKPVVVPGLGRSLGFLPKMPRLRMVHTFLWYLIYGHPASDTVENLCHGSEKWTRKQEPGRTGVPGSSSDLEDSSAAPSSDTPDRATWESEMELSSETVYVDEASWMRYVPPVPVHRDFGFGWALVSDILLCLPLSIFIQIVQVSFKVDRLDEFLNDPVKKHTLIRFLPRTIRQQLLYKRRYIFSVVESLQRLCYMGLLQFGPTEKFQDKDQVFIYLKKKAVILDTTICDPHYNLARSSRPFERRVYVLNSMQDVENYWFDMQCVCLNTPLGVVRCPRAPKNSGPDQSSDEEGSLQKEQERAVDRHNLERKCAMMEYTTGSREIVDEGLIPGDGLGAAGLDSSFYAHLKRNWIWTSYIINKAKRSNTTENGITVRLQTFLSKRPLPLSARGGSRLNLWGEARAGLELRADREEQVEVDREPTLDRNQRVKGGKSQKRKQVKKDPEKKTKRKKKEEPPEEKIKRPRYHDEADQSALQRMTRLRVTWSIQEDGLIMLCRIASNILNPKVKGPFVPWQVVRDILHSTFEESLDKTSHSVGRRARYIVRNPQAYLNYKVCLAEVYQDKALVGEFMNRKCNYEDPKVCASEFKEFVEKLKEKFSSALKNSSLEIPDTLKELFARYRVLMIADKKDQVRKEDKLNSVDDIHFLVLQNLIQSTLALSDRQMEYCQSFQTFRLYREYKDHVLAKAFMEYQRRSLVNRRRVSHMLGPKKNRALPFVPMSYQLSQAYHRIFTWRFPSSICTESFQFFDKIRAAGKWDRPDNFSFKDQENQDSLSDLVAFSLDGPGGHCVATLTLFSLGLIAVDVRIPEQIVVVDSSLVENEVIKSLGKDGATEEDEDEEEDLDEGSGAKRRSIEVKAPQASHTNYLLMRGYCAPGIVSTRNLNPNDSIVVNSCQVKFWLRSTPAPTRLGPTATPLEELTVGTSCLPDMFTRLVKVPEDTYGLEDFAHQVALSGYKPGDVLAALEIQAAIAAAGCFGVDKVRLSRQFSALEKTDAERTRTFSDYVQDLVEHQQVLEVGSSTTRLVTMASAQPWLLRSVQLKGREEDADPPREDPQARPLEGPSGEDGPSERQASPSQSPRGAKRRASWGNADADSQGGGADPEIAQVPPSKRPACHDMPWAPSPGPRGEEEPETPVSMPPMAPEDPGTREPLPGVSEARQEDVGVPSSPGREQLLEGPEDPRGVADGSAAGSLSQAGQERDPENICFIGRPWRIVDGRLNTPVCKGMMEAVLYQVMTRPGIPESCLLQHYQGVLQPLAVLELLQGLEFLGCIKKRLLRKPRSVSLFSKPAIEEVEAPSSLSENLTVSYEPTLDCTIRLGRVFPSEANWNKWVHL", "length": 2115 }, "evidence": [ { "id": "E1BNY8", "url": "https://omabrowser.org/oma/group/E1BNY8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q12789-2", "protein_name": "General transcription factor 3C polypeptide 1", "gene_name": "GTF3C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDALESLLDEVALEGLDGLCLPALWSRLETRVPPFPLPLEPCTQEFLWRALATHPGISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVALEDVYPIHMILENKDGIQGSCRYFKERKNITNDIRTKSLQPRCTMVEAFDRWGKKLIIVASQAMRYRALIGQEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHTTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSVMLSTRTNHIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLRLQEIHPECGPCKTKKGTDVMVRCLKLLKEFKRNDHDDDEDEEVISKTVPPVDIVFERDMLTQTYDLIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYQREKARSELLTTVSLASMQEESLLPEGEDTFLSESDSEEERSSSKRRGRGSQKDTRASANLRPKTQPHHSTPTKGGWKVVNLHPLKKQPPSFPGAAEERACQSLASRDSLLDTSSVSEPNVSFVSHCADSNSGDIAVIEEVRMENPKESSSSLKTGRHSSGQDKPHETYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIVRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKTSQPPVPQGEAEEDSQGKEGPSGSGDSQLSASSRSESGRMKKSDNKMGITPLRNYHPIVVPGLGRSLGFLPKMPRLRVVHMFLWYLIYGHPASNTVEKPSFISERRTIKQESGRAGVRPSSSGSAWEACSEAPSKGSQDGVTWEAEVELATETVYVDDASWMRYIPPIPVHRDFGFGWALVSDILLCLPLSIFIQIVQVSYKVDNLEEFLNDPLKKHTLIRFLPRPIRQQLLYKRRYIFSVVENLQRLCYMGLLQFGPTEKFQDKDQVFIFLKKNAVIVDTTICDPHYNLARSSRPFERRLYVLNSMQDVENYWFDLQCVCLNTPLGVVRCPRVRKNSSTDQGSDEEGSLQKEQESAMDKHNLERKCAMLEYTTGSREVVDEGLIPGDGLGAAGLDSSFYGHLKRNWIWTSYIINQAKKENTAAENGLTVRLQTFLSKRPMPLSARGNSRLNIWGEARVGSELCAGWEEQFEVDREPSLDRNRRVRGGKSQKRKRLKKDPGKKIKRKKKGEFPGEKSKRLRYHDEADQSALQRMTRLRVTWSMQEDGLLVLCRIASNVLNTKVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKNPQAYLNYKVCLAEVYQDKALVGDFMNRRGDYDDPKVCANEFKEFVEKLKEKFSSALRNSNLEIPDTLQELFARYRVLAIGDEKDQTRKEDELNSVDDIHFLVLQNLIQSTLALSDSQMKSYQSFQTFRLYREYKDHVLVKAFMECQKRSLVNRRRVNHTLGPKKNRALPFVPMSYQLSQTYYRIFTWRFPSTICTESFQFLDRMRAAGKLDQPDRFSFKDQDNNEPTNDMVAFSLDGPGGNCVAVLTLFSLGLISVDVRIPEQIIVVDSSMVENEVIKSLGKDGSLEDDEDEEDDLDEGVGGKRRSMEVKPAQASHTNYLLMRGYYSPGIVSTRNLNPNDSIVVNSCQMKFQLRCTPVPARLRPAAAPLEELTMGTSCLPDTFTKLINPQENTCSLEEFVLQLELSGYSPEDLTAALEILEAIIATGCFGIDKEELRRRFSALEKAGGGRTRTFADCIQALLEQHQVLEVGGNTARLVAMGSAWPWLLHSVRLKDREDADIQREDPQARPLEGSSSEDSPPEGQAPPSHSPRGTKRRASWASENGETDAEGTQMTPAKRPALQDSNLAPSLGPGAEDGAEAQAPSPPPALEDTAAAGAAQEDQEGVGEFSSPGQEQLSGQAQPPEGSEDPRGFTESFGAANISQAARERDCESVCFIGRPWRVVDGHLNLPVCKGMMEAMLYHIMTRPGIPESSLLRHYQGVLQPVAVLELLQGLESLGCIRKRWLRKPRPVSLFSTPVVEEVEVPSSLDESPMAFYEPTLDCTLRLGRVFPHEVNWNKWIHL", "length": 2109 }, "evidence": [ { "id": "E1BNY8", "url": "https://omabrowser.org/oma/group/E1BNY8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63505-1", "protein_name": "General transcription factor 3C polypeptide 1", "gene_name": "Gtf3c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDALESLLDEVALEGLDGLCLPALWSRLESRSPAFPLPLEPYTQEFLWRALVTHPGISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVTLEDVYPIHMILENKDGIQGSCRYFKERKDITSSIRSKCLQPRCTMVEAFSRWGKKLIIVASQDMRYRALIGLEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHTTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSMMLSTRSNQIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLPLQEIHPECGPCKTKKGTDVMVRCLKLLKEFRRKMEDDHDDDDDEEAISKAVPPVDIVFERDMLTQTYELIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYAREKARGELLTTVSLASVQDESLMPEGEEAFLSDSESEEESSCSGKRRGRGSRGHSRASGDAGPGSRPHHSTPAKGGWKVLNLHPLKKPKSAAVERSRRSSACRDGLDTSSSSELNIPFDPHSMDSHSGDIAVIEEVRLDNPKEGGGSQKGGRHGSGQDKPHKTYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIIRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKVPPAPAPQEEAEEGNQEPEVPSRSADSEANTSSKPESTRVKKTDEKMGITPLKNYKPVIVPGLGRSIGFLPKMPRLRVMHLFLWYLVYGHPASHTGEQPTFHSERKTGKQEPSRPGVQPSSGDDWDSSEAKNSTESSSWEAEMELSTERVYVDEISWMRYVPPIPIHRDFGFGWALVSDILLCLPLSIFVQVVQVSYKVDNLEDFLNDPLKKHTLIRFLPRHIRQQLLYKRRYIFSVVENLQRLCYMGLLQFGPTEKFQDKDQVFVFLKKNAVIVDTTICDPHYNLAHSSRPFERRLYVLDSMQDVESYWFDLQCICLNTPLGVVRCPCAQKICPDPGSDPEGSLRKEQESAMDKHNLERKCAMLEYTTGSREVVDEGLVPGDGLGAAGLDSSFYAHLKRNWVWTSYIINKARKNNTSENGLTGRLQTFLSKRPMPLGSGGSGRLPLWSEGKADAELCADKEEHFELDREPTPGRNRKVRGGKSQKRKRLKKEPIRKTKRRRRGEHPEAKSKKLRYQDEADQNALRMMTRLRVSWSMQEDGLLMLCRIASNVLNTKVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKNPQAFMNYKVCLAEVYQDKALVGDFMSRKDNYEDPKVCAKEFKEFVEKLKEKFSSGLRNPNLEIPDTLQELFAKYRVLAIGDEKDRVRKEDELNSVEDIHFLVLQNLIQSTLSLSNSQSNSCQSFQIFRLYREFREPVLVRAFMECQKRSLVNRRRVSHSQGPKKNRAVPFVPMSYQLSQSYYKLFTWRFPTTVCTESFQFYDRLRANGILDQPDHFSFKDMDSNDPSSDLVAFSLDSPGGHCVTALALFSLGLLSVDVRIPEQIVVVDSSMVESEVMKSLGKDGGLDDDDEEEDLDEGSGTKRQSVEVKAHQASHTKYLLMRGYYTVPGMVSTRNLNPNDSIVVNSCQVKFRLRNTPAPTHLGPTGPTATPLEELQAGPSCLPASFTSLVDPQLHTRCPEEFAHQMAQSGYSPEDVAASLEILQAVAAADCFGVDREKLSRQFSALEKIADKRTRTFLDYIQDLLEQQQVMEVGGNTVRLVAMASAQPWLLPSVRLKDVEIDTKASGDDSQSRLPAGSSIEDHTSEGAPIPPVSSNGTKKRPYCSIQSPETDAEEATRLPAKKPTLQDVCVAASPRPGTEEQTEAQAQFAAPEDAGAEGPRQESQESVGVSGLEQLGCEFQLPENSEDPRGLTESNMAQVAWESGCERVCFVGRPWRGVDGRLNMPVCKGMMEAVLYHIMSRPGVPESCLLQYYQGVLQPVAVLELLRGLESLGCIQKRMLKKPASVSLFSRPVVEGLGQASEAEALSCQGSTVTFYEPTLDCTIRLGRVFPHDINWKQSGSIYRCVPGQQRSLCPCLIVPPGLSQEPRPSHSCYQSSAQPSTGVATSR", "length": 2148 }, "evidence": [ { "id": "E1BNY8", "url": "https://omabrowser.org/oma/group/E1BNY8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K284-1", "protein_name": "General transcription factor 3C polypeptide 1", "gene_name": "Gtf3c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDALESLLDEVALEGLDGLCLPALWSRLESRSPAFPLPLEPYTQEFLWRALATHPGISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVTLEDVYPIHMILENKDGIQGSCRYFKERKDITSSIRSKCLQPRCTMVEAFSRWGKKLIIVASQDMRYRALIGLEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHTTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSMMLSTRSNQIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLPLQEIHPECGPCKTKKGTDVMVRCLKLLKEFKRKMEDDHDDDDDEEVISKGVPPVDIVFERDMLTQTYELIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYAREKARGELLTTVSLASVQDESLMPEGEEAFLSDSESEEESSCSGGKRRGRGSRGHARASGDAGSGSRPHHSTPAKGGWKVLNLHPLKKPKAAAEERSRRSSACRDGLDTSSSSELNAPFDPHSMDSHSGDIAVIEEVRLDNPKEGGGSQKGGRHGSSQDKPHKTYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIIRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKVPPAPAPQEEAEEENQEPEVPSRSANSDPNTSSKPESTRVKKTDEKMGITPLKNYKPVIVPGLGRSIGFLPKMPRLKAMHLFLWYLVYGHPAGHTGEQPALHSERKTGKQESSRPGAQPSSGDDWDTSEAKNNTESSSWESEMELSTEIVYVDEISWMRYVPPIPIHRDFGFGWALVSDILLCLPLSIFVQLVQVSYKVDNLEDFLNDPLKKHTLIRFLPRHIRQQLLYKRRYIFSVVENLQRLCYMGLLQFGPTEKFQDKDQVFVFLKKNAVIVDTTICDPHYNLAHSSRPFERRLYVLDSMQDVECYWFDLQCICLNTPLGVVRCPCAQKICPDPGSDPEGSLRKEQESAMDKHNLERKCAMLEYTTGSREVVDEGLVPGDGLGAAGLDSSFYAHLKRNWVWTSYIINKARKNNTSENGLTGRLQTFLSKRPMPLGSGGSGRLPLWSEGRADAELCADKEEQFELDREPTPGRNRKVRGGKSQKRKRLKKEPIRKTKRRRRGEHPEAKSKKLRYQDEADQNALRMMTRLRVSWSMQEDGLLMLCRIASNVLNTKVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKNPQAFMNYKVCLAEVYQDKALVGDFMSRKGNYEDPKVCAKEFKEFVEKLKEKFSSGLRNPNLEIPNTLQELFAKYRVLAIGDEKDRVRKEDELNSVEDIHFLVLQNLIQSTLSLSNSQSNSCQSFQIFRLYREFREPVLVRAFMECQKRSLVNRRRVSHSQGPKKNRAVPFVPMSYQLSQSYYKLFTWRFPTTICTESFQFYDRLRTNGMLDQPDHFSFKDLDSSDPSNDLVAFSLDSPGGHCVTALALFSLGLLSVDVRIPEQIVVVDSSMVESEVMKSLGKDGGLDDDEEEEDLDEGSGTKRQGVEVKAHQASHTKYLLMRGYYTVPGMVSTRNLNPNDSIVVNSCQVKFRLRNTPASTQLGPTGFTATPLEELQAGLSCLPASFTSLVDPQLRTHCPEEFAHQMAQSGYSPEDVAASLEILQAVAAADCFGIDKEKLSRQFSALEKIADRRTRTFLDYIQDLLEQEQVMEVGGNTVRLVTMASAQPWLLHSMRLRDMEVDTKASGDDSQSRLPEGPSIEDHTSEGAAVPPVSSHSTKKRPHCPETDAEEATRLPAKKPTLQDVRVAASPRPGAEEQAEAQAPAQLAAPEDADAGGPRQENQENVGVSGLEQLGCEFQLPEGSEDPRGLTESNMAQAAWESGCERVCFVGRPWRGVDGHLNMPVCKGMLEAVLYHIMSRPGVPESCLLQYYQGVLQPVAVLELLRGLESLGCIQKRTLRKPASVSLFSRPVVEGLGQASEAEALSCHESTVTFYEPTLDCTIRLGRVFPHDINWNKWIHL", "length": 2101 }, "evidence": [ { "id": "E1BNY8", "url": "https://omabrowser.org/oma/group/E1BNY8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "transcription factor TFIIIC complex", "id": "GO:0000127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000127", "evidence": [ { "database": "UniProtKB", "id": "E1BNY8", "url": "https://www.uniprot.org/uniprotkb/E1BNY8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BNY8", "url": "https://www.uniprot.org/uniprotkb/E1BNY8" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "E1BNY8", "url": "https://www.uniprot.org/uniprotkb/E1BNY8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "5S class rRNA transcription by RNA polymerase III", "id": "GO:0042791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042791", "evidence": [ { "database": "UniProtKB", "id": "E1BNY8", "url": "https://www.uniprot.org/uniprotkb/E1BNY8" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "E1BNY8", "url": "https://www.uniprot.org/uniprotkb/E1BNY8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BNY8", "url": "https://www.uniprot.org/uniprotkb/E1BNY8" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": 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"end_pos": 175 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 305, "end_pos": 307 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BP03-1", "uniprot_ac": "E1BP03", "uniprot_id": "E1BP03_BOVIN", "mass": { "chemical_mass": 42934.0, "monoisotopic_mass": 42934.0 }, "refseq": { "ac": "NP_001180068", "name": "heparan sulfate glucosamine 3-O-sulfotransferase 3B1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180068" }, "gene_names": [ { "name": "HS3ST3B1", "type": "recommended", "evidence": [ { "id": "E1BP03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP03" } ] }, { "name": "HS3ST3B1", "type": "synonym", "evidence": [ { "id": "NP_001180068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180068" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "E1BP03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP03/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "E1BP03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP03/entry#names_and_taxonomy" } ] }, { "name": "heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1", "type": "synonym", "evidence": [ { "id": "NP_001180068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180068" } ] }, { "name": "heparan sulfate glucosamine 3-O-sulfotransferase 3B1", "type": "synonym", "evidence": [ { "id": "NP_001180068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180068" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BP03", "url": "https://www.uniprot.org/uniprotkb/E1BP03" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HS3ST3B1", "url": "https://www.uniprot.org/uniprotkb/E1BP03", "locus": { "chromosome": "19", "start_pos": 32266271, "end_pos": 32225205, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007866", "url": "https://www.ensembl.org/id/ENSBTAG00000007866" } ] } } ], "crossref": [ { "id": "E1BP03", "url": "https://alphafold.ebi.ac.uk/entry/E1BP03", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007866", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007866", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617069", "url": "https://www.ncbi.nlm.nih.gov/gene/617069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617069", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617069", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFVMSIW", "url": "https://omabrowser.org/oma/group/MFVMSIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BP03", "url": "https://www.orthodb.org/?gene=E1BP03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022928", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001180068", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180068", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BP03", "url": "https://www.uniprot.org/uniprotkb/E1BP03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BP03-1", "url": "https://www.uniprot.org/uniprotkb/E1BP03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQRLSGGRSCLDVPGRLLPQPPPPLPPVRRRLALLFAMLCVWLYLLVYSCAGSCAAAPGLLLLGSGSRAAHAPPAPGPDGSPPRLPFPASPATQSAAGEEMAEGAASQEEQSPETPDSPSPISSFFSGSGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLLVVVRDPVTRAVSDYTQTLSKRPDIPSFESLAFRNRSAGLVDRSWSAIQIGLYAEHLERWLRHFPARQMLFVSGERLVRDPAGELGRVQDFLGLKRIISDKHFYFNQTKGFPCLKKAEGSGRPHCLGKTKGRPHPEIDVQVLRQLRDFYRPFNRKFYQMTGHDFGWD", "length": 388, "header": "tr|E1BP03-1|E1BP03_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=HS3ST3B1 PE=3 SV=1 CANONICAL=E1BP03-1" }, "isoforms": [ { "isoform_ac": "E1BP03-1", "url": "https://www.uniprot.org/uniprotkb/E1BP03/entry#E1BP03-1", "sequence": { "sequence": "MGQRLSGGRSCLDVPGRLLPQPPPPLPPVRRRLALLFAMLCVWLYLLVYSCAGSCAAAPGLLLLGSGSRAAHAPPAPGPDGSPPRLPFPASPATQSAAGEEMAEGAASQEEQSPETPDSPSPISSFFSGSGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLLVVVRDPVTRAVSDYTQTLSKRPDIPSFESLAFRNRSAGLVDRSWSAIQIGLYAEHLERWLRHFPARQMLFVSGERLVRDPAGELGRVQDFLGLKRIISDKHFYFNQTKGFPCLKKAEGSGRPHCLGKTKGRPHPEIDVQVLRQLRDFYRPFNRKFYQMTGHDFGWD", "length": 388, "header": "tr|E1BP03-1|E1BP03_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=HS3ST3B1 PE=3 SV=1 CANONICAL=E1BP03-1" }, "locus": { "chromosome": "19", "start_pos": 32265267, "end_pos": 32225404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010350.6", "url": "https://www.ensembl.org/id/ENSBTAT00000010350.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010350.3", "url": "https://www.ensembl.org/id/ENSBTAP00000010350.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:617069", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617069", "resource": "KEGG Pathway" }, { "id": "R-BTA-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AQB3-1", "protein_name": "Sulfotransferase", "gene_name": "HS3ST3B1L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGQRLNRCLDVPGALPPPLLPLKRRLLLLSIMLFLWLYMFYSCAGSCAALPGLAPRGSAPPEESGPGEPRAAPAALSPISAFLNGSGSKRLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRNYERGLAWYRDLMPRTLEGQITMEKTPSYFVTKEAPARISSMAKGTKLIVVVRDPVTRAISDYTQTLSKKPDIPTFESLTFKNRTTGLIDTSWSAIQIGIYAKHLENWLLYFPIGQILFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSKPHCLGKTKGRTHPDIDQEVVQRLRDFYRPFNMKFYQMTGQDFGWD", "length": 344 }, "evidence": [ { "id": "E1BP03", "url": "https://omabrowser.org/oma/group/E1BP03/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZFR1-1", "protein_name": "Sulfotransferase", "gene_name": "Hs3st3a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPSGPSGAQLSPAEPLSRSIFRKFLLMLCSLLTSLYVFYCLAERCPPGSGPVAGVPGRGVPAGPKELAMWPAGAPRKRLLQLRQRRRRGRPGPGDSSDPDEQSPGLAAAPGGSGAGSSVAEAQPGTLALLLDEGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAMGAEPHFFDRSYHKGLAWYRDLMPRTLEGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPSFESLTFRNRSAGLIDTSWSAIQIGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGLKRIITDKHFYFNQTKGFPCLKKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRDFYRPFNRKFYQMTGRDFGWDG", "length": 393 }, "evidence": [ { "id": "E1BP03", "url": "https://omabrowser.org/oma/group/E1BP03/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BKN6-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 3A1", "gene_name": "Hs3st3a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPSGPTGAQPSPAEPLSRSIFRKFLLMLCSLLTSLYVFYCLAERCPPGSGPVAGVPGRGVPAGPRELAMWPAGAPRKRLLQLRQRRRRGRSGPGDSSDQEEQSPGLAAAPGGSGAGSSVAEAQPGTLALLLDEGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYHKGLAWYRDLMPRTLEGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPSFESLTFRNRSAGLIDTSWSAIQIGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGLKRIITDKHFYFNQTKGFPCLKKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRDFYRPFNRKFYQMTGRDFGWDG", "length": 393 }, "evidence": [ { "id": "E1BP03", "url": "https://omabrowser.org/oma/group/E1BP03/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VWJ7-1", "protein_name": "Heparan sulfate 3-O sulfotransferase-B, isoform B", "gene_name": "Hs3st-B", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRDTAATSAQPAMIVMSIWCSSLSLSSRSLAIALVICVTLVYFSYSFNACLLASISRSLQQSNLRNLLALTSSPRNETNNAANSSSSNSSSSRNSSSTTGAPPAQTVTSSLDGAPKYQLLRQQGLRPSRHLPDTLIIGVKKSGTRALLEFIRLHPDVRAAGSEVHFFDRHYQRGLRWYRHHMPYTIEGQITMEKTPSYFVTKEVPQRVYHMNPATKLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAFVNGSYSVVDTNWGPVKIGVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGRVQDFLGLKRVVTEKHFYFNATKGFPCLFKSEARSTPHCLGKTKGRNHPHIDPGAIERLREFYRPFNNKFYQLTGINFAWP", "length": 384 }, "evidence": [ { "id": "E1BP03", "url": "https://omabrowser.org/oma/group/E1BP03/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y662-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 3B1", "gene_name": "HS3ST3B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQRLSGGRSCLDVPGRLLPQPPPPPPPVRRKLALLFAMLCVWLYMFLYSCAGSCAAAPGLLLLGSGSRAAHDPPALATAPDGTPPRLPFRAPPATPLASGKEMAEGAASPEEQSPEVPDSPSPISSFFSGSGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTFESLTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYRPFNLKFYQMTGHDFGWD", "length": 390 }, "evidence": [ { "id": "E1BP03", "url": "https://omabrowser.org/oma/group/E1BP03/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BP03", "url": "https://www.uniprot.org/uniprotkb/E1BP03" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BP03", "url": "https://www.uniprot.org/uniprotkb/E1BP03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "glycosaminoglycan biosynthetic process", "id": "GO:0006024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006024", "evidence": [ { "database": "UniProtKB", "id": "E1BP03", "url": "https://www.uniprot.org/uniprotkb/E1BP03" } ], "pmid": "" }, { "name": "branching involved in ureteric bud morphogenesis", "id": "GO:0001658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001658", "evidence": [ { "database": "UniProtKB", "id": "E1BP03", "url": "https://www.uniprot.org/uniprotkb/E1BP03" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "E1BP03", "url": "https://www.uniprot.org/uniprotkb/E1BP03" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "[heparan sulfate]-glucosamine 3-sulfotransferase activity", "id": "GO:0008467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008467", "evidence": [ { "database": "UniProtKB", "id": "E1BP03", "url": "https://www.uniprot.org/uniprotkb/E1BP03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-2076611", "name": "HS3ST2-6 sulfate GlcN at C3 in heparan sulfate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKQ1-1", "E1BNJ7-1", "E1BP03-1" ], "evidence": [ { "id": "R-BTA-2076611", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2076611" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BKQ1", "gene_name": "HS3ST2", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BKQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ1" } ] } ] }, { "uniprot_ac": "E1BNJ7", "gene_name": "HS3ST3A1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNJ7" } ] } ] }, { "uniprot_ac": "E1BP03", "gene_name": "HS3ST3B1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { 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CANONICAL=A0AAA9SMG8-1" }, "locus": { "chromosome": "17", "start_pos": 55106243, "end_pos": 55105120, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078301.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078301.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085129.2", "url": "https://www.ensembl.org/id/ENSBTAP00000085129.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:107131393", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107131393", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SMG8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMG8" } ], "pmid": "" }, { "name": "cytosol", 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1MK67-1", "uniprot_ac": "F1MK67", "uniprot_id": "F1MK67_BOVIN", "mass": { "chemical_mass": 22695.0, "monoisotopic_mass": 22695.0 }, "refseq": { "ac": "XP_059745349", "name": "interferon epsilon isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745349" }, "gene_names": [ { "name": "IFNE", "type": "recommended", "evidence": [ { "id": "F1MK67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MK67" } ] }, { "name": "IFNE", "type": "synonym", "evidence": [ { "id": "XP_059745349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745349" } ] } ], "protein_names": [ { "name": "Interferon epsilon", "type": "recommended", "evidence": [ { "id": "F1MK67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MK67/entry#names_and_taxonomy" } ] }, { "name": "Interferon epsilon-1", "type": "synonym", "evidence": [ { "id": "F1MK67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MK67/entry#names_and_taxonomy" } ] }, { "name": "interferon epsilon isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059745349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745349" } ] } ], "function": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR11691", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11691", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11691:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11691:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00143", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00143", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059745349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745349", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1MK67", "url": "https://www.uniprot.org/uniprotkb/F1MK67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MK67-1", "url": "https://www.uniprot.org/uniprotkb/F1MK67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MINKAFFEIVLVLLASSTVCSQELKLVLCQQRRVNQESLKLLNKLQTSSVQQCLPHRKHFLLPQKSVNPHQYQKGQVLAILHEMLQQIFSLFRAIVSLDGWEESHTEKFLVELHQQLEYLEALMRLQAKQKSDTLGSENLRLQVKMYFQRIHDYLESQDYSSCAWTIVQVEINRCLFLVFRLTRKLSEQGMET", "length": 193, "header": "tr|F1MK67-1|F1MK67_BOVIN Isoform 1 of Interferon epsilon OS=Bos taurus OX=9913 GN=IFNE PE=3 SV=2 CANONICAL=F1MK67-1" }, "isoforms": [ { "isoform_ac": "F1MK67-1", "url": "https://www.uniprot.org/uniprotkb/F1MK67/entry#F1MK67-1", "sequence": { "sequence": "MINKAFFEIVLVLLASSTVCSQELKLVLCQQRRVNQESLKLLNKLQTSSVQQCLPHRKHFLLPQKSVNPHQYQKGQVLAILHEMLQQIFSLFRAIVSLDGWEESHTEKFLVELHQQLEYLEALMRLQAKQKSDTLGSENLRLQVKMYFQRIHDYLESQDYSSCAWTIVQVEINRCLFLVFRLTRKLSEQGMET", "length": 193, "header": "tr|F1MK67-1|F1MK67_BOVIN Isoform 1 of Interferon epsilon OS=Bos taurus OX=9913 GN=IFNE PE=3 SV=2 CANONICAL=F1MK67-1" }, "locus": { "chromosome": "8", "start_pos": 22531481, "end_pos": 22530903, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140247.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140247.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105272.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105272.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A7UHZ5-1", "protein_name": "Interferon epsilon", "gene_name": "IFNE", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MINKSFFEIMLVLLASSTGFSRELKLVLSQQRRVNRESLKLLNKLQTSSIQQCLPHRKNFLLPQKSMNPHQYQKQQALAILHEMLQQIFSLFRAVISLDGWEESHMEEFLVELHQQLEYLEALMRLQAEQKSDTLCSENLTLQVKMYFQRIRDYLENQDYSSCAWTIVRVEINRCLFFVFQLTGKLSKQGMEP", "length": 193 }, "evidence": [ { "id": "F1MK67", "url": "https://omabrowser.org/oma/group/F1MK67/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1LVL8-1", "protein_name": "Interferon epsilon", "gene_name": "Ifne", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVHKQLPKMLLLLASFAIFSLEPKLILFQSRRNRESLQLLKALPSSSVQLCLAHRKNFLLPQQSVSPHQHQEGHVLAVLHEILQQIFVLFQTHSSRGVWEENHIEEVLAALHRQLGYLESLGGLKAERKSGGLSVKDLRLQIKAYFRRIHDYLENHRYSTCAWIIVQIEVNRCMFFVSRLARRLNSQDIDS", "length": 191 }, "evidence": [ { "id": "F1MK67", "url": "https://omabrowser.org/oma/group/F1MK67/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I0I6-1", "protein_name": "Interferon epsilon", "gene_name": "Ifne", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIHKQLPEMVLLLLASSTVFSLEPKSILFQSRMKRESLHLLKTLPISSVYQCLAHRKNFQLPWQSVSRHQYQKGHVLAVLHELLQQIFSLFQAHVSRGIWEENHIERVLGALHQQLEYVELLAGLKAESKSGGLSAQSLRLQIKSYFRRIHDYLENQRYSSCAWIVVQVEINRCMFFVFRLTAWLNKQETDP", "length": 192 }, "evidence": [ { "id": "F1MK67", "url": "https://omabrowser.org/oma/group/F1MK67/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q80ZF2-1", "protein_name": "Interferon epsilon", "gene_name": "Ifne", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVHRQLPETVLLLLVSSTIFSLEPKRIPFQLWMNRESLQLLKPLPSSSVQQCLAHRKNFLLPQQPVSPHQYQEGQVLAVVHEILQQIFTLLQTHGTMGIWEENHIEKVLAALHRQLEYVESLGGLNAAQKSGGSSAQNLRLQIKAYFRRIHDYLENQRYSSCAWIIVQTEIHRCMFFVFRFTTWLSRQDPDP", "length": 192 }, "evidence": [ { "id": "F1MK67", "url": "https://omabrowser.org/oma/group/F1MK67/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86WN2-1", "protein_name": "Interferon epsilon", "gene_name": "IFNE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIIKHFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNFLLPQKSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYLEALMGLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFVFSLTEKLSKQGRPLNDMKQELTTEFRSPR", "length": 208 }, "evidence": [ { "id": "F1MK67", "url": "https://omabrowser.org/oma/group/F1MK67/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "B cell activation involved in immune response", "id": "GO:0002312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002312", "evidence": [ { "database": "UniProtKB", "id": "F1MK67", "url": "https://www.uniprot.org/uniprotkb/F1MK67" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "F1MK67", "url": "https://www.uniprot.org/uniprotkb/F1MK67" } ], "pmid": "" }, { "name": "type I interferon-mediated signaling pathway", "id": "GO:0060337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060337", "evidence": [ { "database": "UniProtKB", "id": "F1MK67", "url": "https://www.uniprot.org/uniprotkb/F1MK67" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", 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"MRLVTVVTVFLTLGTVVDAKTTQPNSMDCAEGENVNLPCNHSIIHGEDYIHWYRQNPSQSPQYVIHGLRGTVNNSMASLHIASDRKSSTLVLLQVTLRDTAVYYCTLRE", "length": 109, "header": "tr|A0AA87CIZ8-1|A0AA87CIZ8_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0AA87CIZ8-1" }, "locus": { "chromosome": "10", "start_pos": 22894771, "end_pos": 22894003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149291.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149291.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107173.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107173.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AA87CIZ8", "url": "https://www.uniprot.org/uniprotkb/A0AA87CIZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0AA87CIZ8", "url": "https://www.uniprot.org/uniprotkb/A0AA87CIZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AA87CIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AA87CIZ8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 109, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 40, "end_pos": 42 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0AAA9SBC9-1", "uniprot_ac": "A0AAA9SBC9", "uniprot_id": "A0AAA9SBC9_BOVIN", "mass": { "chemical_mass": 125467.0, "monoisotopic_mass": 125467.0 }, "refseq": { "ac": "XP_010813714", "name": "zinc finger protein 11-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010813714" }, "gene_names": [ { "name": "LOC618289", "type": "recommended", "evidence": [ { "id": "A0AAA9SBC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9" } ] }, { "name": "LOC618289", "type": "synonym", "evidence": [ { "id": "XP_010813714", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010813714" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0AAA9SBC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 11-like", "type": "synonym", "evidence": [ { "id": "XP_010813714", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010813714" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SBC9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC618289", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000045581", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045581", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "618289", "url": "https://www.ncbi.nlm.nih.gov/gene/618289", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF75", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF75", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010813714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010813714", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RTP8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBC9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBC9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNH7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNH7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3C6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3C6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3C6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHSEGRLMFQDVAIDFTQEEWESLDPSQRKLYRDVMVENYRNLASLGLVSKVDLVTFLELLKDPRNIRRMEATAIYPAMSPQDTQGLMPKNPALEDLFPKANEGMYQIFHLRNLNLMTDWEYTRVYERQKVYLYGHKEMETVTHNANRTAKRNEQHESNWEKQQLQSSTSAETCKCLRKDFHPFMKHMCSLKENVKNLEGNLIFIANTHSDNCERRLRLNIHSRMSEHLQFNNECENSQTKQFEGSMSRVSLFFPKQIFSIHSKIYNVDDNGRDEIQPSWFNTYCGMVNTQQLSMYNKMSQTLNKSHISNNYKSICGGLRSCSDNETRYTVEEDSNLKKHQGPESSNKDSKSNKCRNTFDQISGFSLDKSTCTGDRTCSEYGKVSNHCSELTQQDIVQNAQEENKCKICEKVFSKSSNLSRHRRIHTGRKPFKCTECCTAFNCHSLLTQHQRIHAGEKPYICKECNKAFHRSSFLIEHQRIHTGEKPYKCTVCGKAFMYNSRLIQHQQIHAGEKPYKCTDCSKAFTYNSLLIQHRRIHTGEKPYKCTECSKAFTYNSHLIQHQRIHTGERPYKCTECSKAFTYNSLLTQHRRIHTGEKPYKCTECSKAFIYNSLLIQHQRIHTGEKPFKCTECSKAFTCNSDLIEHKRIHTGEKPYICKECNKAFRRSSFLTEHQRIHTGEKPYKCTVCGKAFTYNSRLIQHQRIHAEEKPYKCTECSKAFTRKSVLIKHRQIHTGEKPYKCTECSKAFTYNSRLIEHQQIHAGEKPYKCTECSKAFTYNSLLIKHRRIHSGEKPYKCTECSKAFPCNSDLIEHQRIHTGEKPYICKECNKAFRRSSFLTRHQRIHAGEKPYKCTVCGKAFTYNSSLIQHQRIHTGEKHYKCTECSKAFTCNSLLIQHQQNHTGEKPYKCTVCGKAFTYNSRLIKHQRIHAGEKPYKCTECSKAFTYNSLLIQHRRIHTGEKPYKCTECSKTFTYNSRLIQHQRIHSGEKPYKCTECSKAFTCNSSLIQHQRIHTGEKPYICKECNKAFHRSSFLTQHQRIHTGEKPYKCTECGKAFTYHSNLIQHKRIHAR", "length": 1073, "header": "tr|A0AAA9SBC9-1|A0AAA9SBC9_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC618289 PE=3 SV=1 CANONICAL=A0AAA9SBC9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RTP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9/entry#A0AAA9RTP8-1", "sequence": { "sequence": "MTHSEGRLTFQDVAIDFTQEEWECLDPGQRKLYRDVMVENYRNLASLGLVSKVDLVTFLELLKDPRNMRRMETTAIYPAMSPQDTQDMMPKNPALEDVFPKANLGMYQTFHLRNLNLMEDWEYTRVYERQRGCLYGHKEIETVTQYANITAKRNDQSESNWEKQQLQSSISAEKCKCLTKDFHPFLKHTCCLKENVENLEGNLVSTANTHSDNSEHRLPLNIHSSMSEHVQFNNECENSQSKQFEGSMSRVSLFFPQQISSIHSKIYNVDDNGRDAFQPSLFNTYCGMVNTEQLSMYNKRSQTLSKSPSSNNYKSIYGGLRRYSGNETRYTVEGDSNLKKPQGPESSNKDSKSNKCRNTFDQMSGFSLDKSTCTGERTCGQYGKVSNHCSELTQQDAVQNPQEENKCKICEKVFSKSSNLSRHRRIHTGRKPFKCTECCTAFNCHSLLTQHQRIHAGEKPYICKDCNKAFRRSSFLTQHQRIHTGEKPYKCTVCGKAFTYNSSLIKHQRIHAGEKPYKCTECSKAFTYNSLLIQHQQIHTGEKPYKCTECGKAFTYNSRLIEHQQIHAGEKPYKCTECSKAFIYNSLLIKHRRIHSGEKPYKCTECSKAFTYNSSLIQHRRIHTGEKPYKCTECSKAFIYNSLLIQHRRIHTGEKPYKCTECSKAFTYNSSLIQHRRIHSGEKPHKCTECSKAFTYNSLLIQHRRIHTGEKPYKCTECSKAFTCNSALIEHQQIHTGEKPYKCTECSKAFTYNSRLTEHQRIHTGEKPYKCTECSKAFTCNSDRIEHQRIHTGEKLYICKECNKAFRRSSFLTRHQLIHTGEKPYKCTECSKAFICYSDLTHHQRIHTGEKPYMCKECNKAFHHFSVLSQHHRIHTGEKPYKCKECGKAFIRSSAFTQHHQIHTGDRRYKCTECGKAFITRYNLTEHWHMHTGERPYKCTECGKAFSRSGHLTIHLRTHTGKKL", "length": 964, "header": "tr|A0AAA9RTP8-1|A0AAA9SBC9_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC618289 PE=3 SV=1 CANONICAL=A0AAA9SBC9-1" }, "locus": { "chromosome": "18", "start_pos": 60390485, "end_pos": 60291325, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095960.2", "url": "https://www.ensembl.org/id/ENSBTAT00000095960.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075333.2", "url": "https://www.ensembl.org/id/ENSBTAP00000075333.2" } ] } }, { "isoform_ac": "A0AAA9SBC9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9/entry#A0AAA9SBC9-1", "sequence": { "sequence": "MTHSEGRLMFQDVAIDFTQEEWESLDPSQRKLYRDVMVENYRNLASLGLVSKVDLVTFLELLKDPRNIRRMEATAIYPAMSPQDTQGLMPKNPALEDLFPKANEGMYQIFHLRNLNLMTDWEYTRVYERQKVYLYGHKEMETVTHNANRTAKRNEQHESNWEKQQLQSSTSAETCKCLRKDFHPFMKHMCSLKENVKNLEGNLIFIANTHSDNCERRLRLNIHSRMSEHLQFNNECENSQTKQFEGSMSRVSLFFPKQIFSIHSKIYNVDDNGRDEIQPSWFNTYCGMVNTQQLSMYNKMSQTLNKSHISNNYKSICGGLRSCSDNETRYTVEEDSNLKKHQGPESSNKDSKSNKCRNTFDQISGFSLDKSTCTGDRTCSEYGKVSNHCSELTQQDIVQNAQEENKCKICEKVFSKSSNLSRHRRIHTGRKPFKCTECCTAFNCHSLLTQHQRIHAGEKPYICKECNKAFHRSSFLIEHQRIHTGEKPYKCTVCGKAFMYNSRLIQHQQIHAGEKPYKCTDCSKAFTYNSLLIQHRRIHTGEKPYKCTECSKAFTYNSHLIQHQRIHTGERPYKCTECSKAFTYNSLLTQHRRIHTGEKPYKCTECSKAFIYNSLLIQHQRIHTGEKPFKCTECSKAFTCNSDLIEHKRIHTGEKPYICKECNKAFRRSSFLTEHQRIHTGEKPYKCTVCGKAFTYNSRLIQHQRIHAEEKPYKCTECSKAFTRKSVLIKHRQIHTGEKPYKCTECSKAFTYNSRLIEHQQIHAGEKPYKCTECSKAFTYNSLLIKHRRIHSGEKPYKCTECSKAFPCNSDLIEHQRIHTGEKPYICKECNKAFRRSSFLTRHQRIHAGEKPYKCTVCGKAFTYNSSLIQHQRIHTGEKHYKCTECSKAFTCNSLLIQHQQNHTGEKPYKCTVCGKAFTYNSRLIKHQRIHAGEKPYKCTECSKAFTYNSLLIQHRRIHTGEKPYKCTECSKTFTYNSRLIQHQRIHSGEKPYKCTECSKAFTCNSSLIQHQRIHTGEKPYICKECNKAFHRSSFLTQHQRIHTGEKPYKCTECGKAFTYHSNLIQHKRIHAR", "length": 1073, "header": "tr|A0AAA9SBC9-1|A0AAA9SBC9_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC618289 PE=3 SV=1 CANONICAL=A0AAA9SBC9-1" }, "locus": { "chromosome": "18", "start_pos": 60357314, "end_pos": 60345282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111721.2", "url": "https://www.ensembl.org/id/ENSBTAT00000111721.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082693.2", "url": "https://www.ensembl.org/id/ENSBTAP00000082693.2" } ] } }, { "isoform_ac": "A0AAA9TNH7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9/entry#A0AAA9TNH7-1", "sequence": { "sequence": "MTHSEGRLTFQDVAIDFTQEEWECLDPGQRKLYRDVMVENYRNLASLAMSPQDTQGLMPKNPALEDLFPKANEGMYQIFHLRNLNLMTDWEYTRVYERQKVYLYGHKEMETVTHNANRTAKRNEQHESNWEKQQLQSSTSAETCKCLRKDFHPFMKHMCSLKENVKNLEGNLIFIANTHSDNCERRLRLNIHSRMSEHLQFNNECENSQTKQFEGSMSRVSLFFPKQIFSIHSKIYNVDDNGRDEIQPSWFNTYCGMVNTQQLSMYNKMSQTLNKSHISNNYKSICGGLRSCSDNETRYTVEEDSNLKKHQGPESSNKDSKSNKCRNTFDQISGFSLDKSTCTGDRTCSEYGKVSNHCSELTQQDIVQNAQEENKCKICEKVFSKSSNLSRHRRIHTGRKPFKCTECCTAFNCHSLLTQHQRIHAGEKPYICKECNKAFHRSSFLIEHQRIHTGEKPYKCTVCGKAFMYNSRLIQHQQIHAGEKPYKCTDCSKAFTYNSLLIQHRRIHTGEKPYKCTECSKAFTYNSHLIQHQRIHTGERPYKCTECSKAFTYNSLLTQHRRIHTGEKPYKCTECSKAFIYNSLLIQHQRIHTGEKPFKCTECSKAFTCNSDLIEHKRIHTGEKPYICKECNKAFRRSSFLTEHQRIHTGEKPYKCTVCGKAFTYNSRLIQHQRIHAEEKPYKCTECSKAFTRKSVLIKHRQIHTGEKPYKCTECSKAFTYNSRLIEHQQIHAGEKPYKCTECSKAFTYNSLLIKHRRIHSGEKPYKCTECSKAFPCNSDLIEHQRIHTGEKPYICKECNKAFRRSSFLTRHQRIHAGEKPYKCTVCGKAFTYNSSLIQHQRIHTGEKHYKCTECSKAFTCNSLLIQHQQNHTGEKPYKCTVCGKAFTYNSRLIKHQRIHAGEKPYKCTECSKAFTYNSLLIQHRRIHTGEKPYKCTECSKTFTYNSRLIQHQRIHSGEKPYKCTECSKAFTCNSSLIQHQRIHTGEKPYICKECNKAFHRSSFLTQHQRIHTGEKPYKCTECGKAFTYHSNLIQHKRIHAR", "length": 1042, "header": "tr|A0AAA9TNH7-1|A0AAA9TNH7_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC618289 PE=3 SV=1 CANONICAL=A0AAA9SBC9-1" }, "locus": { "chromosome": "18", "start_pos": 60390485, "end_pos": 60345282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128917.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128917.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100091.2", "url": "https://www.ensembl.org/id/ENSBTAP00000100091.2" } ] } }, { "isoform_ac": "A0ABI0P3C6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9/entry#A0ABI0P3C6-1", "sequence": { "sequence": "MTHSEGRLTFQDVAIDFTQEEWECLDPGQRKLYRDVMVENYRNLASLAMSPQDTQDMMPKNPALEDVFPKANLGMYQTFHLRNLNLMEDWEYTRVYERQRGCLYGHKEIETVTQYANITAKRNDQSESNWEKQQLQSSISAEKCKCLTKDFHPFLKHTCCLKENVENLEGNLVSTANTHSDNSEHRLPLNIHSSMSEHVQFNNECENSQSKQFEGSMSRVSLFFPQQISSIHSKIYNVDDNGRDAFQPSLFNTYCGMVNTEQLSMYNKRSQTLSKSPSSNNYKSIYGGLRRYSGNETRYTVEGDSKLKKHQGPESSNKDSKSNKCRNTFDQMSGFSLDKSTCTGERTCSEYGKVSNHCSELTQQDIVQNAQEENKCKICEKVFSKSSNLSRHRRIHTGRKPFKCTECCTAFNCHSLLTQHQRIHAGEKPYICKECNKAFHRSSFLIEHQRIHTGEKPYKCTVCGKAFMYNSRLIQHQQIHAGEKPYKCTDCSKAFTYNSLLIQHRRIHTGEKPYKCTECSKAFTYNSHLIQHQRIHTGERPYKCTECSKAFTYNSLLTQHRRIHTGEKPYKCTECSKAFIYNSLLIQHQRIHTGEKPFKCTECSKAFTCNSDLIEHKRIHTGEKPYICKECNKAFRRSSFLTEHQRIHTGEKPYKCTVCGKAFTYNSRLIQHQRIHAEEKPYKCTECSKAFTRKSVLIKHRQIHTGEKPYKCTECSKAFTYNSRLIEHQQIHAGEKPYKCTECSKAFTYNSLLIKHRRIHSGEKPYKCTECSKAFPCNSDLIEHQRIHTGEKPYICKECNKAFRRSSFLTRHQRIHAGEKPYKCTVCGKAFTYNSSLIQHQRIHTGEKHYKCTECSKAFTCNSLLIQHQQNHTGEKPYKCTVCGKAFTYNSRLIKHQRIHAGEKPYKCTECSKAFTYNSLLIQHRRIHTGEKPYKCTECSKTFTYNSRLIQHQRIHSGEKPYKCTECSKAFTCNSSLIQHQRIHTGEKPYICKECNKAFHRSSFLTQHQRIHTGEKPYKCTECGKAFTYHSNLIQHKRIHAR", "length": 1042, "header": "tr|A0ABI0P3C6-1|A0ABI0P3C6_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC618289 PE=3 SV=1 CANONICAL=A0AAA9SBC9-1" }, "locus": { "chromosome": "18", "start_pos": 60390485, "end_pos": 60345282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142572.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142572.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105464.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105464.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SBC9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SBC9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SBC9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SBC9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SBC9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1005, "end_pos": 1007, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 865, "end_pos": 867, "annotation": "n_glycosylation_sequon" }, { "start_pos": 902, "end_pos": 904, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9SBC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 405, "end_pos": 432, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0AAA9SBC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBC9" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 78, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1005, "end_pos": 1007 }, { "start_pos": 148, "end_pos": 150 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 865, "end_pos": 867 }, { "start_pos": 902, "end_pos": 904 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0AAA9S020-1", "uniprot_ac": "A0AAA9S020", "uniprot_id": "A0AAA9S020_BOVIN", "mass": { "chemical_mass": 77303.0, "monoisotopic_mass": 77303.0 }, "refseq": {}, "gene_names": [ { "name": "LOC785630", "type": "recommended", "evidence": [ { "id": "A0AAA9S020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S020" } ] } ], "protein_names": [ { "name": "Zinc finger protein 665", "type": "recommended", "evidence": [ { "id": "A0AAA9S020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S020/entry#names_and_taxonomy" } ] } ], 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"https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF371", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF371", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S020", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S020", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S020-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S020-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AQLTFKDVFIDFTPEEWDCLDPAQRTLYKDVMVETLRNLLSVDVSQIRMIKKLQAKGNSGKEESFQRVVFGTAESHEIEDFFLRKVQENMHDFECLWTDDERNDRGTSTSHNNNLTNRRDHDSRSDAGNKPVERHGSSFQDQLQILESEGTVSECSQVVANINISASGLPPQRTRSVHKGNSHKQESAVIHPSELVPDQEAHKKNTYSCNECNITFLQDSELTRHQRIHTGRKAYKCNICCQAFNDKSTLIVHQRNHTGEKPYKCDVCGHCFKQHTHLQYHRRVHTGEKPYKCDVCGKAFSRKARRTVHQTLHTGEKPYTCEVCGHGYTRSTYLAIHQRVHTGEKPYKCDVCGKAFFVSGSLTSHRKVHTREKPYKCDVCGKAFSVNGRLKSHRNIHTGEKPYKCDVCGKAFCVNGSLTSHRKVHTREKPYKCDVCGKAFSVNGSLTSHRKVHTGEKPYKCDVCGKAFSVNGKLKSHRNIHTGEKPYKCNVCGKAFRVIGGLTSHRKIHTGEKPYKCDVCGKAFSVNGKLKSHRNIHTGEKPYKCDVCGKAFRVNGGLTSHRKIHTGEKPYKCDVCGKAFSVNGRLKSHRNIHTGEKPYKCDVCGKAFRVNGGLTSHQKIHTGEKPYKCDVCGKAFSFNASLAVHRRIHTGEKPYKCVVCGKAFRQTASFAVHRRIHSGEKLRG", "length": 684, "header": "tr|A0AAA9S020-1|A0AAA9S020_BOVIN Isoform 1 of Zinc finger protein 665 OS=Bos taurus OX=9913 GN=LOC785630 PE=3 SV=1 CANONICAL=A0AAA9S020-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S020-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S020/entry#A0AAA9S020-1", "sequence": { "sequence": "AQLTFKDVFIDFTPEEWDCLDPAQRTLYKDVMVETLRNLLSVDVSQIRMIKKLQAKGNSGKEESFQRVVFGTAESHEIEDFFLRKVQENMHDFECLWTDDERNDRGTSTSHNNNLTNRRDHDSRSDAGNKPVERHGSSFQDQLQILESEGTVSECSQVVANINISASGLPPQRTRSVHKGNSHKQESAVIHPSELVPDQEAHKKNTYSCNECNITFLQDSELTRHQRIHTGRKAYKCNICCQAFNDKSTLIVHQRNHTGEKPYKCDVCGHCFKQHTHLQYHRRVHTGEKPYKCDVCGKAFSRKARRTVHQTLHTGEKPYTCEVCGHGYTRSTYLAIHQRVHTGEKPYKCDVCGKAFFVSGSLTSHRKVHTREKPYKCDVCGKAFSVNGRLKSHRNIHTGEKPYKCDVCGKAFCVNGSLTSHRKVHTREKPYKCDVCGKAFSVNGSLTSHRKVHTGEKPYKCDVCGKAFSVNGKLKSHRNIHTGEKPYKCNVCGKAFRVIGGLTSHRKIHTGEKPYKCDVCGKAFSVNGKLKSHRNIHTGEKPYKCDVCGKAFRVNGGLTSHRKIHTGEKPYKCDVCGKAFSVNGRLKSHRNIHTGEKPYKCDVCGKAFRVNGGLTSHQKIHTGEKPYKCDVCGKAFSFNASLAVHRRIHTGEKPYKCVVCGKAFRQTASFAVHRRIHSGEKLRG", "length": 684, "header": "tr|A0AAA9S020-1|A0AAA9S020_BOVIN Isoform 1 of Zinc finger protein 665 OS=Bos taurus OX=9913 GN=LOC785630 PE=3 SV=1 CANONICAL=A0AAA9S020-1" }, "locus": { "chromosome": "18", "start_pos": 58792134, "end_pos": 58782153, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105804.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105804.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079198.2", "url": "https://www.ensembl.org/id/ENSBTAP00000079198.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S020", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S020" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of 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OX=9913 GN=LOC104968656 PE=3 SV=1 CANONICAL=A0AAA9S197-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S197-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S197/entry#A0AAA9S197-1", "sequence": { "sequence": "MAKRLQARRLDGIDHNPWVEFVQLASEEADVVNLGQGFPDFSPPEFAVEAFQHAVSGDFMLNQYTKAFGYPPLTKILANFFGKLLGQEIDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPFDCYEPMTLMAGGRPVFVSLKPSPTQKGEPDSSSNWQLDPTELASKFTSRTKAFILNTPNNPLGKVFSKEELELVASLCQQHDVVCISDEVYQWMVFDGFQHISIASLPGMWERTLTIGSAGKTFSVTGWKVGWVLGPDSLMKHLRTVHQNSIYHCATQGQAAVAQSFEREQLHFGRPSSYFVQLPQYIQRCRDHMIQSLQSMGFRPVIPQGSYFLITDISDFKNKMPDLPGAAGEPYDRRFVKWMIKNKGLVAIPMSVFFSLPHQKFFDHYIRFCFVKDESTLRAMDQKLQKWKAELTP", "length": 424, "header": "tr|A0AAA9S197-1|A0AAA9S197_BOVIN Isoform 1 of Kynurenine--oxoglutarate transaminase 1 OS=Bos taurus OX=9913 GN=LOC104968656 PE=3 SV=1 CANONICAL=A0AAA9S197-1" }, "locus": { "chromosome": "11", "start_pos": 99362537, "end_pos": 99351294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132108.2", "url": 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"https://www.uniprot.org/uniprotkb/A0AAA9S197" } ], "pmid": "" }, { "name": "cysteine-S-conjugate beta-lyase activity", "id": "GO:0047804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047804", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S197", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S197" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17593", "name": "", "equation": "3-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TKC4-1", "A0AAA9S197-1" ], "evidence": [ { "id": "17593", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17593" } ] }, { "id": "18121", "name": "", "equation": "an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TKC4-1", "A0AAF6YGX9-1", "Q0P5G4-1", "A0AAA9S197-1" ], "evidence": [ { "id": "18121", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18121" } ] }, { "id": "65560", "name": "", "equation": "L-kynurenine + 2-oxoglutarate = kynurenate + L-glutamate + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TKC4-1", "A0AAF6YGX9-1", "Q5E9N4-1", "Q0P5G4-1", "A0AAA9S9L4-1", "A0A3Q1LKR3-1", "A0AAA9S197-1" ], "evidence": [ { "id": "65560", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/65560" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LKR3", "gene_name": "AADAT", "activity": [ { "ec_number": "2.6.1.63", "activity": "L-kynurenine + glyoxylate = kynurenate + glycine + H2O.", "evidence": [ { "id": "A0A3Q1LKR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKR3" } ] }, { "ec_number": "2.6.1.39", "activity": "L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate.", "evidence": [ { "id": "A0A3Q1LKR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKR3" } ] }, { "ec_number": "2.6.1.7", "activity": "L-kynurenine + 2-oxoglutarate = kynurenate + L-glutamate + H2O.", "evidence": [ { "id": "A0A3Q1LKR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKR3" } ] }, { "ec_number": "2.6.1.4", "activity": "glycine + 2-oxoglutarate = glyoxylate + L-glutamate.", "evidence": [ { "id": "A0A3Q1LKR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKR3" } ] }, { "ec_number": "2.6.1.73", "activity": "glyoxylate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + glycine.", "evidence": [ { "id": "A0A3Q1LKR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKR3" } ] }, { "ec_number": "2.6.1.63", "activity": "", "evidence": [ { "id": "A0A3Q1LKR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKR3" } ] }, { "ec_number": "2.6.1.73", "activity": "", "evidence": [ { "id": "A0A3Q1LKR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKR3" } ] }, { "ec_number": "2.6.1.39", "activity": "", "evidence": [ { "id": "A0A3Q1LKR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKR3" } ] }, { "ec_number": "2.6.1.4", "activity": "", "evidence": [ { "id": "A0A3Q1LKR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKR3" } ] }, { "ec_number": "2.6.1.7", "activity": "", "evidence": [ { "id": "A0A3Q1LKR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKR3" } ] } ] }, { "uniprot_ac": "A0AAA9S197", "gene_name": "LOC104968656", "activity": [ { "ec_number": "2.6.1.64", "activity": "3-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine.", "evidence": [ { "id": "A0AAA9S197", "database": "UniProtKB", "url": 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"id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA. Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides. In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety. However, the triacylglycerol hydrolase activity is controversial and may be very low. Possesses phospholipase A2 activity.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S3G3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3#function" }, { "database": "UniProtKB", "id": "ARBA00053171", "url": "https://www.uniprot.org/uniprotkb/ARBA00053171#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S3G3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC100297709", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3", "locus": {} } ], "crossref": [ { "id": "cd07221", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07221", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100297709", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF01734", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01734", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024848590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024848590", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12044", "url": "https://www.rhea-db.org/rhea/12044", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19709", "url": "https://www.rhea-db.org/rhea/19709", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37131", "url": "https://www.rhea-db.org/rhea/37131", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37143", "url": "https://www.rhea-db.org/rhea/37143", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37159", "url": "https://www.rhea-db.org/rhea/37159", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37443", "url": 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"https://www.uniprot.org/uniprotkb/A0AAA9S3G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3G3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYDAESGWSLSFAGCGFLGFYHVGVTRCLSEHAPHLLRHARKFFGASAGALHCSFFLSGIPLDQTLQILMDLTRSARSQKFGIVHPGFSLSKHIRDGLQRHLPDNVHQLVSGKMVISLTRVSDGKNVLVSDFHSKDEVVDALCCSSYVPFICGWIPPSFRGVRYVDGGISDNIPFVDTKRTITVSPFYGESDICPKVKSTFFLNEGFTKLNMQFCTENLYLMFQSLFPPDVKVLGELCLQGYVDALRFLEKNGIRDGPHPCLSAPPAESEPRSLEPFLGVAPREAGPKPVELLDHLHLSMLTWDESVLETQSPELSMALRKAVRNPDGYRNRICNFLPVKIMSYVMLPCTLPVESAIAVVQRLVTWLPDMPSDIQWLWSATSHVCSQAMVRLLPASRSQIPASSQRPSSTNPDTVGVAGLSAPPRTWTRTLWMSCRGQS", "length": 439, "header": "tr|A0AAA9S3G3-1|A0AAA9S3G3_BOVIN Isoform 1 of Acylglycerol transacylase OS=Bos taurus OX=9913 GN=LOC100297709 PE=4 SV=1 CANONICAL=A0AAA9S3G3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S3G3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3/entry#A0AAA9S3G3-1", "sequence": { "sequence": "MYDAESGWSLSFAGCGFLGFYHVGVTRCLSEHAPHLLRHARKFFGASAGALHCSFFLSGIPLDQTLQILMDLTRSARSQKFGIVHPGFSLSKHIRDGLQRHLPDNVHQLVSGKMVISLTRVSDGKNVLVSDFHSKDEVVDALCCSSYVPFICGWIPPSFRGVRYVDGGISDNIPFVDTKRTITVSPFYGESDICPKVKSTFFLNEGFTKLNMQFCTENLYLMFQSLFPPDVKVLGELCLQGYVDALRFLEKNGIRDGPHPCLSAPPAESEPRSLEPFLGVAPREAGPKPVELLDHLHLSMLTWDESVLETQSPELSMALRKAVRNPDGYRNRICNFLPVKIMSYVMLPCTLPVESAIAVVQRLVTWLPDMPSDIQWLWSATSHVCSQAMVRLLPASRSQIPASSQRPSSTNPDTVGVAGLSAPPRTWTRTLWMSCRGQS", "length": 439, "header": "tr|A0AAA9S3G3-1|A0AAA9S3G3_BOVIN Isoform 1 of Acylglycerol transacylase OS=Bos taurus OX=9913 GN=LOC100297709 PE=4 SV=1 CANONICAL=A0AAA9S3G3-1" }, "locus": { "chromosome": "5", "start_pos": 114682680, "end_pos": 114655486, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119121.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119121.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079643.2", "url": "https://www.ensembl.org/id/ENSBTAP00000079643.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "1-acylglycerol-3-phosphate O-acyltransferase activity", "id": "GO:0003841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003841", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S3G3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S3G3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "triglyceride catabolic process", "id": "GO:0019433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019433", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S3G3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12044", "name": "", "equation": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PK46-1", "A0A3Q1LV96-1", "A0A3Q1MLE6-1", "Q3SZ79-1", "E1BJQ9-1", "Q5EA42-1", "P11151-1", "P16386-1", "P30122-1", "Q29458-1", "Q2KI18-1", "F1MC21-1", "Q0P5B7-1", "A0A3Q1M7B8-1", "F6RA94-1", "G5E5T0-1", "A0A3Q1LR40-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "12044", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12044" } ] }, { "id": "19709", "name": "", "equation": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95JH2-1", "A0AAA9S2I6-1", "A0AAA9SAV7-1", "Q5E9R2-1", "E1B770-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "19709", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19709" } ] }, { "id": "37131", "name": "", "equation": "1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95JH2-1", "A0AAA9SAV7-1", "E1B770-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "37131", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37131" } ] }, { "id": "37143", "name": "", "equation": "1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95JH2-1", "A0AAA9SAV7-1", "E1B770-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "37143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37143" } ] }, { "id": "37159", "name": "", "equation": "1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95JH2-1", "A0AAA9SAV7-1", "E1B770-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "37159", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37159" } ] }, { "id": "37443", "name": "", "equation": "1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95JH2-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "37443", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37443" } ] }, { "id": "38323", "name": "", "equation": "2 1-(9Z-octadecenoyl)-glycerol = 1,2-di-(9Z-octadecenoyl)-glycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "38323", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38323" } ] }, { "id": "38327", "name": "", "equation": "1-(9Z-octadecenoyl)-glycerol + 1,2-di-(9Z-octadecenoyl)-glycerol = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "38327", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38327" } ] }, { "id": "38331", "name": "", "equation": "1-(9Z-octadecenoyl)-glycerol + 1,3-di-(9Z-octadecenoyl)-glycerol = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "38331", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38331" } ] }, { "id": "38387", "name": "", "equation": "1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = 1,3-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "38387", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38387" } ] }, { "id": "44432", "name": "", "equation": "2 a 1-acylglycerol = a 1,2-diacylglycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "44432", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44432" } ] }, { "id": "44436", "name": "", "equation": "a 1-acylglycerol + a 1,2-diacylglycerol = a triacylglycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "44436", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44436" } ] }, { "id": "44440", "name": "", "equation": "a 1-acylglycerol + a 1,3-diacylglycerol = a triacylglycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "44440", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44440" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LR40", "gene_name": "LIPG", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] } ] }, { "uniprot_ac": "A0A3Q1LV96", "gene_name": "PLB1", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] } ] }, { "uniprot_ac": "A0A3Q1M7B8", "gene_name": "PNLIPRP1", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1M7B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7B8" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A3Q1M7B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7B8" } ] } ] }, { "uniprot_ac": "A0A3Q1MLE6", "gene_name": "LIPE", "activity": [ { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.79", "activity": "a monoacylglycerol + H2O = glycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.23", "activity": "", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.79", "activity": "", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] } ] }, { "uniprot_ac": "A0AAA9S2I6", "gene_name": "AGPAT4", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0AAA9S2I6", "database": 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"end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIM0#function" }, { "id": "A0ABI0NIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIM0" }, { "id": "PIRSR605002-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR605002-3" } ], "binding_site_uniprot": 222, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 222, "end_pos": 222, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIM0#function" }, { "id": "A0ABI0NIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIM0" }, { "id": "PIRSR605002-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR605002-3" } ], "binding_site_uniprot": 225, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 225, "end_pos": 225, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.4.2.8", "ec_name": "alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.", "evidence": [ { "id": "5.4.2.8", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.8" }, { "id": "5.4.2.8", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.4.2.8" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NKK4-1", "uniprot_ac": "A0ABI0NKK4", "uniprot_id": "A0ABI0NKK4_BOVIN", "mass": { "chemical_mass": 106287.0, "monoisotopic_mass": 106287.0 }, "refseq": {}, "gene_names": [ { "name": "TUBGCP2", "type": "recommended", "evidence": [ { "id": "A0ABI0NKK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKK4" } ] } ], "protein_names": [ { "name": "Gamma-tubulin complex component", "type": "recommended", "evidence": [ { "id": "A0ABI0NKK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKK4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0P2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0P2#function" }, { "database": "UniProtKB", "id": "RU363050", "url": "https://www.uniprot.org/uniprotkb/RU363050#function" } ] }, { "annotation": "Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation. Plays a role in neuronal migration.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKK4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKK4#function" }, { "database": "UniProtKB", "id": "ARBA00093403", "url": "https://www.uniprot.org/uniprotkb/ARBA00093403#function" }, { "database": "UniProtKB", "id": "A0ABI0NIM4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIM4#function" }, { "database": "UniProtKB", "id": "A0ABI0NJV5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJV5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKK4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKK4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TUBGCP2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKK4", "locus": {} } ], "crossref": [ { "id": "IPR007259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19302:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19302:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NIM4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NIM4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJV5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJV5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKK4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKK4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0P2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0P2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0P2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDRETLQYLQQNAKERAELAASAAASSTASFGAPATASKISMQELEELRKQLGNVATGPTWQQYPPPQCFWKLGALGDHCSLSVPAGPCLPASAQGAQSLELTRKMLRDKQNKKNSGQRLPVFPAWVYERPTLLGDFLTGSGTSTDAAVPIGTLPLASQEAAIVEDLLYVLVGVDGRYITAQPLTGRQSRTFLVDPNLDLSIRELVSRILPVAASYSTVTRFIEEKSSFEYGQVNHALAAAMRTLLKEYLILVTQLEQLQRQGLLSLQKLWFYIQPAMRTVDILASLATSVDKGECVGGATLSLLHDRSFSYTGDSQAQELCLYLTTAASVPYFEILEKWIYRGIIDDPYSEFMVEEHELRKEKIQEDYNDKYWELRYTVVQRHIPSFLQKMAGKVLSTGKYLNVVRECGHDVTCPAAKEVIYTLKERAYVEQIEKAFGYASKVLLGFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLTEEELKKPVDDITPTRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAMVHADPTELTLSGLEAFSFDYVVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHSLHSAKWFAGAFTLRQRMLNFVQNVQYYMMLEVVEPTWHVLEKSLRSASTIDDVLGHHASFLDGCLKDCMLTNPELLRVFSKLMSVCVMFTNCMQRFTQSMKLDSELGRLTLEHGTMQGPPTEAERAEERTRKELARKCLAEHVDAPQLASSFEATINKFDKNFSAHLLDLLARLSVYSTSDCEHGMASVISRLDFNGFYTERLEHLSAERSQKVAPPVPGPRGPPAPAPRVAVPAQ", "length": 940, "header": "tr|A0ABI0NKK4-1|A0ABI0NKK4_BOVIN Isoform 1 of Gamma-tubulin complex component OS=Bos taurus OX=9913 GN=TUBGCP2 PE=3 SV=1 CANONICAL=A0ABI0NKK4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NIM4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKK4/entry#A0ABI0NIM4-1", "sequence": { "sequence": "MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDRETLQYLQQNAKERAELAASAAASSTASFGAPATASKISMQELEELRKQLGNVATGPTWQQSLELTRKMLRDKQNKKNSGQRLPVFPAWVYERPTLLGDFLTGSGTSTDAAVPIGTLPLASQEAAIVEDLLYVLVGVDGRYITAQPLTGRQSRTFLVDPNLDLSIRELVSRILPVAASYSTVTRFIEEKSSFEYGQVNHALAAAMRTLLKEYLILVTQLEQLQRQGLLSLQKLWFYIQPAMRTVDILASLATSVDKGECVGGATLSLLHDRSFSYTGDSQAQELCLYLTTAASVPYFEILEKWIYRGIIDDPYSEFMVEEHELRKEKIQEDYNDKYWELRYTVVQRHIPSFLQKMAGKVLSTGKYLNVVRECGHDVTCPAAKEVIYTLKERAYVEQIEKAFGYASKVLLGFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLTEEELKKPVDDITPTRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAMVHADPTELTLSGLEAFSFDYVVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHSLHSAKWFAGAFTLRQRMLNFVQNVQYYMMLEVVEPTWHVLEKSLRSASTIDDVLGHHASFLDGCLKDCMLTNPELLRVFSKLMSVCVMFTNCMQRFTQSMKLDSELGRLTLEHGTMQGPPTEAERAEERTRKELARKCLAEHVDAPQLASSFEATINKFDKNFSAHLLDLLARLSVYSTSDCEHGMASVISRWAPAAPSPPTALRPPAP", "length": 878, "header": "tr|A0ABI0NIM4-1|A0ABI0NKK4_BOVIN Computationally mapped isoform of Gamma-tubulin complex component OS=Bos taurus OX=9913 GN=TUBGCP2 PE=3 SV=1 CANONICAL=A0ABI0NKK4-1" }, "locus": { "chromosome": "26", "start_pos": 25730334, "end_pos": 25717104, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150107.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150107.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104059.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104059.1" } ] } }, { "isoform_ac": "A0ABI0NJV5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKK4/entry#A0ABI0NJV5-1", "sequence": { "sequence": "MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDRETLQYLQQNAKERAELAASAAASSTASFGAPATASKISMQELEELRKQLGNVATGPTWQQSLELTRKMLRDKQNKKNSGQRLPVFPAWVYERPTLLGDFLTGSGTSTDAAVPIGTLPLASQEAAIVEDLLYVLVGVDGRYITAQPLTGRQSRTFLVDPNLDLSIRELVSRILPVAASYSTVTRFIEEKSSFEYGQVNHALAAAMRTLLKEYLILVTQLEQLQRQGLLSLQKLWFYIQPAMRTVDILASLATSVDKGECVGGATLSLLHDRSFSYTGDSQAQELCLYLTTAASVPYFEILEKWIYRGIIDDPYSEFMVEEHELRKEKIQEDYNDKYWELRYTVVQRHIPSFLQKMAGKVLSTGKYLNVVRECGHDVTCPAAKEVIYTLKERAYVEQIEKAFGYASKVLLGFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLTEEELKKPVDDITPTRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAMVHADPTELTLSGLEAFSFDYVVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHSLHSAKWFAGAFTLRQRMLNFVQNVQYYMMLEVVEPTWHVLEKSLRSASTIDDVLGHHASFLDGCLKDCMLTNPELLRVFSKLMSVCVMFTNCMQCLAEHVDAPQLASSFEATINKFDKNFSAHLLDLLARLSVYSTSDCEHGMASVISRLDFNGFYTERLEHLSAERSQKVAPPVPGPRGPPAPAPRVAVPAQ", "length": 862, "header": "tr|A0ABI0NJV5-1|A0ABI0NJV5_BOVIN Computationally mapped isoform of Gamma-tubulin complex component OS=Bos taurus OX=9913 GN=TUBGCP2 PE=3 SV=1 CANONICAL=A0ABI0NKK4-1" }, "locus": { "chromosome": "26", "start_pos": 25731398, "end_pos": 25717104, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142942.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142942.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104803.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104803.1" } ] } }, { "isoform_ac": "A0ABI0NKK4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKK4/entry#A0ABI0NKK4-1", "sequence": { "sequence": "MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDRETLQYLQQNAKERAELAASAAASSTASFGAPATASKISMQELEELRKQLGNVATGPTWQQYPPPQCFWKLGALGDHCSLSVPAGPCLPASAQGAQSLELTRKMLRDKQNKKNSGQRLPVFPAWVYERPTLLGDFLTGSGTSTDAAVPIGTLPLASQEAAIVEDLLYVLVGVDGRYITAQPLTGRQSRTFLVDPNLDLSIRELVSRILPVAASYSTVTRFIEEKSSFEYGQVNHALAAAMRTLLKEYLILVTQLEQLQRQGLLSLQKLWFYIQPAMRTVDILASLATSVDKGECVGGATLSLLHDRSFSYTGDSQAQELCLYLTTAASVPYFEILEKWIYRGIIDDPYSEFMVEEHELRKEKIQEDYNDKYWELRYTVVQRHIPSFLQKMAGKVLSTGKYLNVVRECGHDVTCPAAKEVIYTLKERAYVEQIEKAFGYASKVLLGFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLTEEELKKPVDDITPTRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAMVHADPTELTLSGLEAFSFDYVVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHSLHSAKWFAGAFTLRQRMLNFVQNVQYYMMLEVVEPTWHVLEKSLRSASTIDDVLGHHASFLDGCLKDCMLTNPELLRVFSKLMSVCVMFTNCMQRFTQSMKLDSELGRLTLEHGTMQGPPTEAERAEERTRKELARKCLAEHVDAPQLASSFEATINKFDKNFSAHLLDLLARLSVYSTSDCEHGMASVISRLDFNGFYTERLEHLSAERSQKVAPPVPGPRGPPAPAPRVAVPAQ", "length": 940, "header": "tr|A0ABI0NKK4-1|A0ABI0NKK4_BOVIN Isoform 1 of Gamma-tubulin complex component OS=Bos taurus OX=9913 GN=TUBGCP2 PE=3 SV=1 CANONICAL=A0ABI0NKK4-1" }, "locus": { "chromosome": "26", "start_pos": 25731398, "end_pos": 25717104, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144698.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144698.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105271.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105271.1" } ] } }, { "isoform_ac": "A0ABI0P0P2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKK4/entry#A0ABI0P0P2-1", "sequence": { "sequence": 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { 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"ARBA00003729", "url": "https://www.uniprot.org/uniprotkb/ARBA00003729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ25" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ25", "locus": {} } ], "crossref": [ { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NJ25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ25-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSSSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPLGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0NJ73-1|A0ABI0NJ73_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC132344681 PE=4 SV=1 CANONICAL=A0ABI0NJ73-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NJ73-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ73/entry#A0ABI0NJ73-1", "sequence": { "sequence": 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"ENSBTAP00000104942.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104942.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ73", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ73" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ73", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ73" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ73", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ73" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ73", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NJ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ73" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 343, "end_pos": 371, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 68, 96 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NJ80-1", "uniprot_ac": "A0ABI0NJ80", "uniprot_id": "A0ABI0NJ80_BOVIN", "mass": { "chemical_mass": 58736.0, "monoisotopic_mass": 58736.0 }, "refseq": { "ac": "NP_001137552", "name": "insulinoma-associated protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137552" }, "gene_names": [ { "name": "INSM2", "type": "recommended", "evidence": [ { "id": "A0ABI0NJ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ80" } ] }, { "name": "INSM2", "type": "synonym", "evidence": [ { "id": "NP_001137552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137552" } ] } ], "protein_names": [ { "name": "Insulinoma-associated protein 2", "type": "recommended", "evidence": [ { "id": "A0ABI0NJ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ80/entry#names_and_taxonomy" } ] }, { "name": "insulinoma-associated protein 2", "type": "synonym", "evidence": [ { "id": "NP_001137552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137552" } ] } ], "function": [ { "annotation": "May function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ80", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ80#function" }, { "database": "UniProtKB", "id": "ARBA00060130", "url": "https://www.uniprot.org/uniprotkb/ARBA00060130#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ80", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ80" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "INSM2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ80", "locus": {} } ], "crossref": [ { "id": "614156", "url": "https://www.ncbi.nlm.nih.gov/gene/614156", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614156", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614156", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR15065", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15065", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15065:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15065:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001137552", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137552", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ80", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ80-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRGFLVKRTKRTGGSYRVRLAERVFPLFPRPPGTPPFPEEASSAPQPGVEREAHPTPEEEEARELSGSSCPAARVSPAAGGREGAEWRADGREGPGPSPSPTKPAGVELRRAFLERCLSSPVSAESFPGGAAAVASFSCSVAPAAAPTSGEQFLLPLRAPFPEPALHPDPAPLSATLHGLKRATGGERRAKAPSGCASGPAAAGVKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGPGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAATISSADGKLPPSSSSSDSGTVASFLAEGKENSRAERTEDQHPRARDSSGTEQHQDSAPQPGLQVLSHPEPPLPQLPYTAGVLGRRVPEPGSASGVGGPEIFVCPYCHKKFRRQAYLRKHLGTHEAGSARALGPCFGSERGGPLAFACPLCGAHFPSADIRDKHRLWHAVRDELLLPALAGAPPDAPNPGRAPDGDAQQIFSCKHCPSTFFSSPGLTRHINKCHPSESRQVLLLQMPLRPGC", "length": 554, "header": "tr|A0ABI0NJ80-1|A0ABI0NJ80_BOVIN Isoform 1 of Insulinoma-associated protein 2 OS=Bos taurus OX=9913 GN=INSM2 PE=4 SV=1 CANONICAL=A0ABI0NJ80-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NJ80-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ80/entry#A0ABI0NJ80-1", "sequence": { "sequence": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NJD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJD4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRSTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYKQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPKTKVVIQVSLEPLQPGLVEVASITVNASDYERSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0NJD4-1|A0ABI0NJD4_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NJD4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NJD4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJD4/entry#A0ABI0NJD4-1", "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRSTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYKQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPKTKVVIQVSLEPLQPGLVEVASITVNASDYERSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0NJD4-1|A0ABI0NJD4_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NJD4-1" }, "locus": { "chromosome": "Y", "start_pos": 40559766, "end_pos": 40558138, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138674.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138674.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104773.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104773.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJD4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJD4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJD4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NJD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJD4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 343, "end_pos": 371, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 68, 96 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NJE0-1", "uniprot_ac": "A0ABI0NJE0", "uniprot_id": "A0ABI0NJE0_BOVIN", "mass": { "chemical_mass": 50932.0, "monoisotopic_mass": 50932.0 }, "refseq": {}, "gene_names": [ { "name": "ARMT1", "type": "recommended", "evidence": [ { "id": "A0ABI0NJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJE0" } ] } ], "protein_names": [ { "name": "Sugar phosphate phosphatase", "type": "recommended", "evidence": [ { "id": "A0ABI0NJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJE0/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.-", "type": "synonym", "evidence": [ { "id": "A0ABI0NJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJE0/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.-", "type": "synonym", "evidence": [ { "id": "A0ABI0NJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJE0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJE0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJE0#function" }, { "database": "UniProtKB", "id": "ARBA00045980", "url": "https://www.uniprot.org/uniprotkb/ARBA00045980#function" }, { "database": "UniProtKB", "id": "RU367030", "url": "https://www.uniprot.org/uniprotkb/RU367030#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJE0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJE0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARMT1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJE0", "locus": { "chromosome": "9", "start_pos": 88498999, "end_pos": 88485487, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004098", "url": "https://www.ensembl.org/id/ENSBTAG00000004098" } ] } } ], "crossref": [ { "id": "IPR002791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12260:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12260:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "24452", "url": "https://www.rhea-db.org/rhea/24452", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "28002", "url": "https://www.rhea-db.org/rhea/28002", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "35603", "url": "https://www.rhea-db.org/rhea/35603", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NJE0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJE0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJE0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPPASLSARDVGSFAYLSVKDRSPQILTKAIDTLHRHKSEFFEKHGEKGLEAEKKAISLLSKLRNELQTDKPIVPLVEKFVDTDIWNQYLEYQQSLLNESDGKPRWFLSPWLFVECYMYRRIHEAIIQSPPIDDFDIFKEFKDQNFFESQESIIALCTHLQELRKTIEDLDENQLKNEFFKVLQISLWGNKCDLSLSGGEHISQKTNIMNSLEDLKPFILVNDMDRLWSLLSNCKKTREKESVTRVDIVLDNSGFELITDLVLADFLLSSKLATKIHFYGKTIPWFVSDTTLHDFNWIIKQLKHSNNKWVSQCGVDWEDHVKTGRWVYLDHIFWTLPHEFSAVSQVAPDLHAALQKAHLIFFKGDLNYRKLTGDRRWEFTVPFHEALSGFHPAPLCSIRTLKAEVQVGLQPGQGEQLTASEPNWLTAGKYGVFQFDGPL", "length": 441, "header": "tr|A0ABI0NJE0-1|A0ABI0NJE0_BOVIN Isoform 1 of Sugar phosphate phosphatase OS=Bos taurus OX=9913 GN=ARMT1 PE=3 SV=1 CANONICAL=A0ABI0NJE0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NJE0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJE0/entry#A0ABI0NJE0-1", "sequence": { "sequence": "MAGPPASLSARDVGSFAYLSVKDRSPQILTKAIDTLHRHKSEFFEKHGEKGLEAEKKAISLLSKLRNELQTDKPIVPLVEKFVDTDIWNQYLEYQQSLLNESDGKPRWFLSPWLFVECYMYRRIHEAIIQSPPIDDFDIFKEFKDQNFFESQESIIALCTHLQELRKTIEDLDENQLKNEFFKVLQISLWGNKCDLSLSGGEHISQKTNIMNSLEDLKPFILVNDMDRLWSLLSNCKKTREKESVTRVDIVLDNSGFELITDLVLADFLLSSKLATKIHFYGKTIPWFVSDTTLHDFNWIIKQLKHSNNKWVSQCGVDWEDHVKTGRWVYLDHIFWTLPHEFSAVSQVAPDLHAALQKAHLIFFKGDLNYRKLTGDRRWEFTVPFHEALSGFHPAPLCSIRTLKAEVQVGLQPGQGEQLTASEPNWLTAGKYGVFQFDGPL", "length": 441, "header": "tr|A0ABI0NJE0-1|A0ABI0NJE0_BOVIN Isoform 1 of Sugar phosphate phosphatase OS=Bos taurus OX=9913 GN=ARMT1 PE=3 SV=1 CANONICAL=A0ABI0NJE0-1" }, "locus": { "chromosome": "9", "start_pos": 88498090, "end_pos": 88485509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153539.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153539.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104524.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104524.1" } ] } } ], "glycosylation": [], 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{ "uniprot_canonical_ac": "A0ABI0NJL5-1", "uniprot_ac": "A0ABI0NJL5", "uniprot_id": "A0ABI0NJL5_BOVIN", "mass": { "chemical_mass": 34928.0, "monoisotopic_mass": 34928.0 }, "refseq": { "ac": "NP_001376830", "name": "olfactory receptor family 52 subfamily L member 2", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376830" }, "gene_names": [ { "name": "OR52L2", "type": "recommended", "evidence": [ { "id": "A0ABI0NJL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJL5" } ] }, { "name": "OR52L1", "type": "synonym", "evidence": [ { "id": "NP_001376830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376830" } ] }, { "name": "OR52L2", "type": "synonym", "evidence": [ { "id": "NP_001376830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376830" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NJL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJL5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 52 subfamily L member 2", "type": "synonym", "evidence": [ { "id": "NP_001376830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376830" } ] }, { "name": "olfactory receptor, family 52, subfamily L, member 1", "type": "synonym", "evidence": [ { "id": "NP_001376830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376830" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJL5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJL5#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376830", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376830" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJL5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJL5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJL5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJL5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR52L2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJL5", "locus": {} } ], "crossref": [ { "id": "cd15951", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377518" }, "gene_names": [ { "name": "OR4D2E", "type": "recommended", "evidence": [ { "id": "A0ABI0NK12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK12" } ] }, { "name": "OR4D2E", "type": "synonym", "evidence": [ { "id": "NP_001377518", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377518" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NK12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK12/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily D member 2E", "type": "synonym", "evidence": [ { "id": "NP_001377518", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377518" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376803" }, "gene_names": [ { "name": "OR2J3D", "type": "recommended", "evidence": [ { "id": "A0ABI0NK65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK65" } ] }, { "name": "OR2J3D", "type": "synonym", "evidence": [ { "id": "NP_001376803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376803" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NK65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK65/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 2 subfamily J member 3D", "type": "synonym", "evidence": [ { "id": "NP_001376803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376803" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376803", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376803" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NK65", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK65#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NK65", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK65" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2J3D", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK65", "locus": {} } ], "crossref": [ { "id": "cd15947", "url": 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"site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NK72", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK72#function" }, { "database": "UniProtKB", "id": "ARBA00045382", "url": "https://www.uniprot.org/uniprotkb/ARBA00045382#function" } ] }, { "annotation": "Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NK72", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK72#function" }, { "database": "UniProtKB", "id": "PIRNR038093", "url": "https://www.uniprot.org/uniprotkb/PIRNR038093#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], 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"Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NK99", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NK99-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYU4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYU4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSLSRVRLLATPWTAAYQAPPSMGLFRQEYWSGLPLPSPGNMEEERTAAELQKNVIQDTVVFEDVAVDFTQEEWALLNLAQRNLYRDVMLENFRNLASLGFEIQLKINESVAPQDAYGKISNEQDVAGFKKSDSSLSILHKIWEYHDVDYQNKNHKRSLRIHGIENIYEHNEENQCGQTVSQISHLNIPKRTTEVRAYECHVCKKAFIDHLSLKNHIRSHTGSKPYQCKECGKAFHFFACFKKHMKTPTEEKPYECQECTKAFSCSSFFRAHMKIHAGKTSCECRECGKTFSCSSSLTEHKRIHSGDKPYECKECGKAFSCSSSLSKHKRIHSGDKPYECKECGKAFSSSSHLIIHIRIHTGEKPYECQECGKAFSESSKLTVHVRTHTGEKPYKCKECGKAYNCPSSLSIHMRKHTGEKPYECLECGKAFYLPTSLNTHVKNQSREKPYECKECGKAFSCPSSFRAHVRDHTGKAQYECKECGKAFSRSSSLTEHLRTHSGEKPYECKECGKAFISSSHLTVHIRTHTGEKPYECKKCGKAFIYPSALRIHMRTHTGEKPYECKECGKAFRHSSYLTVHTRMHTGEKPFECLECGKAFSCPSSFRRHVRSHTGEKPYECKECGKAFVCPAYFRRHVKTHTRENV", "length": 646, "header": "tr|A0ABI0NK99-1|A0ABI0NK99_BOVIN Isoform 1 of Zinc finger protein 699 OS=Bos taurus OX=9913 GN=ZNF699 PE=3 SV=1 CANONICAL=A0ABI0NK99-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NK99-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK99/entry#A0ABI0NK99-1", "sequence": { "sequence": "MKSLSRVRLLATPWTAAYQAPPSMGLFRQEYWSGLPLPSPGNMEEERTAAELQKNVIQDTVVFEDVAVDFTQEEWALLNLAQRNLYRDVMLENFRNLASLGFEIQLKINESVAPQDAYGKISNEQDVAGFKKSDSSLSILHKIWEYHDVDYQNKNHKRSLRIHGIENIYEHNEENQCGQTVSQISHLNIPKRTTEVRAYECHVCKKAFIDHLSLKNHIRSHTGSKPYQCKECGKAFHFFACFKKHMKTPTEEKPYECQECTKAFSCSSFFRAHMKIHAGKTSCECRECGKTFSCSSSLTEHKRIHSGDKPYECKECGKAFSCSSSLSKHKRIHSGDKPYECKECGKAFSSSSHLIIHIRIHTGEKPYECQECGKAFSESSKLTVHVRTHTGEKPYKCKECGKAYNCPSSLSIHMRKHTGEKPYECLECGKAFYLPTSLNTHVKNQSREKPYECKECGKAFSCPSSFRAHVRDHTGKAQYECKECGKAFSRSSSLTEHLRTHSGEKPYECKECGKAFISSSHLTVHIRTHTGEKPYECKKCGKAFIYPSALRIHMRTHTGEKPYECKECGKAFRHSSYLTVHTRMHTGEKPFECLECGKAFSCPSSFRRHVRSHTGEKPYECKECGKAFVCPAYFRRHVKTHTRENV", "length": 646, "header": "tr|A0ABI0NK99-1|A0ABI0NK99_BOVIN Isoform 1 of Zinc finger protein 699 OS=Bos taurus OX=9913 GN=ZNF699 PE=3 SV=1 CANONICAL=A0ABI0NK99-1" }, "locus": { "chromosome": "7", "start_pos": 14209589, "end_pos": 14193614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146124.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146124.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105067.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105067.1" } ] } }, { "isoform_ac": "A0ABI0NYU4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK99/entry#A0ABI0NYU4-1", "sequence": { "sequence": "MEEERTAAELQKNVIQDTVVFEDVAVDFTQEEWALLNLAQRNLYRDVMLENFRNLASLGFEIQLKINESVAPQDAYGKISNEQDVAGFKKSDSSLSILHKIWEYHDVDYQNKNHKRSLRIHGIENIYEHNEENQCGQTVSQISHLNIPKRTTEVRAYECHVCKKAFIDHLSLKNHIRSHTGSKPYQCKECGKAFHFFACFKKHMKTPTEEKPYECQECTKAFSCSSFFRAHMKIHAGKTSCECRECGKTFSCSSSLTEHKRIHSGDKPYECKECGKAFSCSSSLSKHKRIHSGDKPYECKECGKAFSSSSHLIIHIRIHTGEKPYECQECGKAFSESSKLTVHVRTHTGEKPYKCKECGKAYNCPSSLSIHMRKHTGEKPYECLECGKAFYLPTSLNTHVKNQSREKPYECKECGKAFSCPSSFRAHVRDHTGKAQYECKECGKAFSRSSSLTEHLRTHSGEKPYECKECGKAFISSSHLTVHIRTHTGEKPYECKKCGKAFIYPSALRIHMRTHTGEKPYECKECGKAFRHSSYLTVHTRMHTGEKPFECLECGKAFSCPSSFRRHVRSHTGDLLSQGLNPRLLCLLHWQEDSFALHHLGSPSSGYLSFLNVCICLCLVTYIYIKHLLYIIYM", "length": 634, "header": "tr|A0ABI0NYU4-1|A0ABI0NYU4_BOVIN Computationally mapped isoform of Zinc finger protein 699 OS=Bos taurus OX=9913 GN=ZNF699 PE=3 SV=1 CANONICAL=A0ABI0NK99-1" }, "locus": { "chromosome": "7", "start_pos": 14205659, "end_pos": 14190409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136281.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136281.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105528.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105528.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NK99", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NK99", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NK99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK99" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 226, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NK99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK99" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 140, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 444, "end_pos": 446 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NKE9-1", "uniprot_ac": "A0ABI0NKE9", "uniprot_id": "A0ABI0NKE9_BOVIN", "mass": { "chemical_mass": 54268.0, "monoisotopic_mass": 54268.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Envelope protein syncytin-rum1", "type": "recommended", "evidence": [ { "id": "A0ABI0NKE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKE9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKE9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKE9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKE9", "locus": {} } ], "crossref": [ { "id": "IPR018154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10424:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10424:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NKE9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKE9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLIIYVSLLLLTPNILSLPLDPQDNVFLSWAHSYAAFHNPSNCWVCGALPSLSVEGFPWWTSPLQDKDFLQVCEYLRQQSRAMPLLHLMTSTNPKMDWCNTLYSNYGHNVTFNFDYTLSRFNDYFATYKENRSRSNGFLPDIYQIWDEVTWLTPEKGHLISTASMCWEQTEPSPKVSQQLNYNDWKQMGYLSQETCNVIIPVFSNPSSGSPFVWPGTNWDWISQSRWLAPNGTYWICGSYLWAWLPPGWIGRCTLGLAFTHGFIFSELPEKPANLPHLRTRWARSVFYWYDYLAAAFVPSLGTTDVMLRVDALTNFTQQALQDSQKAISALNAEQAQIRKVVLQNRLALDILTAAQGGTCAIIHTQYCTYIPDMSTNVTHFTNHMNKMIRAMDTPEASIASLWKTLTNSPWWTTILITIILVVLFLLFAPCICNCITGFVSSRMKAFKLQMVAQTPATAVASSSYYLGPLDQISSI", "length": 477, "header": "tr|A0ABI0NKE9-1|A0ABI0NKE9_BOVIN Isoform 1 of Envelope protein syncytin-rum1 OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NKE9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NKE9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKE9/entry#A0ABI0NKE9-1", "sequence": { "sequence": "MSLIIYVSLLLLTPNILSLPLDPQDNVFLSWAHSYAAFHNPSNCWVCGALPSLSVEGFPWWTSPLQDKDFLQVCEYLRQQSRAMPLLHLMTSTNPKMDWCNTLYSNYGHNVTFNFDYTLSRFNDYFATYKENRSRSNGFLPDIYQIWDEVTWLTPEKGHLISTASMCWEQTEPSPKVSQQLNYNDWKQMGYLSQETCNVIIPVFSNPSSGSPFVWPGTNWDWISQSRWLAPNGTYWICGSYLWAWLPPGWIGRCTLGLAFTHGFIFSELPEKPANLPHLRTRWARSVFYWYDYLAAAFVPSLGTTDVMLRVDALTNFTQQALQDSQKAISALNAEQAQIRKVVLQNRLALDILTAAQGGTCAIIHTQYCTYIPDMSTNVTHFTNHMNKMIRAMDTPEASIASLWKTLTNSPWWTTILITIILVVLFLLFAPCICNCITGFVSSRMKAFKLQMVAQTPATAVASSSYYLGPLDQISSI", "length": 477, "header": "tr|A0ABI0NKE9-1|A0ABI0NKE9_BOVIN Isoform 1 of Envelope protein syncytin-rum1 OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NKE9-1" }, "locus": { "chromosome": "Y", "start_pos": 52282409, "end_pos": 52280979, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151124.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151124.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105150.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105150.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 132, "end_pos": 134 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 378, "end_pos": 380 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40/entry#names_and_taxonomy" } ] }, { "name": "ADPRibase-Mn", "type": "synonym", "evidence": [ { "id": "A0ABI0NL40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40/entry#names_and_taxonomy" } ] }, { "name": "CDP-choline phosphohydrolase", "type": "synonym", "evidence": [ { "id": "A0ABI0NL40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. 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[9913]" } ], "gene": [ { "name": "ADPRM", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40", "locus": { "chromosome": "19", "start_pos": 29675727, "end_pos": 29667132, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046919", "url": "https://www.ensembl.org/id/ENSBTAG00000046919" } ] } } ], "crossref": [ { "id": "cd07396", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07396", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534038", "url": "https://www.ncbi.nlm.nih.gov/gene/534038", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534038", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534038", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR16509", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16509", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16509:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16509:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "10412", "url": "https://www.rhea-db.org/rhea/10412", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "21692", "url": "https://www.rhea-db.org/rhea/21692", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "32487", "url": "https://www.rhea-db.org/rhea/32487", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NL40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL40-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0Y4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3X7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3X7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEPLTLMRGRALKESYLEVMDYKPEPELLSESSERLFSFGVIADIQYADLEDGYNFQGNRRRYYRHSLLHLQGAIEHWNQERSPPRCVLQLGDIIDGYNAQYKASEKSLERVMNTFQMLRVPVHHTWGNHEFYNFSRDYLTNSKLNTKFLEDQIAHHPETVPSEDYYAYHFVPFPKFRFILLDAYDMSVLGVDQSSPKYQQCLKILREHNPNTELNSPQGLREPQFVQFNGGFSPEQLNWLNAVLTFSDRNQEKVVIVSHLPIYPEASDSVCLAWNYRDALAVIWSHKCVVCFFAGHTHDGGYSEDPYGVHHVNIEGVIETAPDSQAFGTVHVYPDKMMLEGRGRVPHRIMNYRKE", "length": 357, "header": "tr|A0ABI0NL40-1|A0ABI0NL40_BOVIN Isoform 1 of Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase OS=Bos taurus OX=9913 GN=ADPRM PE=3 SV=1 CANONICAL=A0ABI0NL40-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NL40-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40/entry#A0ABI0NL40-1", "sequence": { "sequence": "MTEPLTLMRGRALKESYLEVMDYKPEPELLSESSERLFSFGVIADIQYADLEDGYNFQGNRRRYYRHSLLHLQGAIEHWNQERSPPRCVLQLGDIIDGYNAQYKASEKSLERVMNTFQMLRVPVHHTWGNHEFYNFSRDYLTNSKLNTKFLEDQIAHHPETVPSEDYYAYHFVPFPKFRFILLDAYDMSVLGVDQSSPKYQQCLKILREHNPNTELNSPQGLREPQFVQFNGGFSPEQLNWLNAVLTFSDRNQEKVVIVSHLPIYPEASDSVCLAWNYRDALAVIWSHKCVVCFFAGHTHDGGYSEDPYGVHHVNIEGVIETAPDSQAFGTVHVYPDKMMLEGRGRVPHRIMNYRKE", "length": 357, "header": "tr|A0ABI0NL40-1|A0ABI0NL40_BOVIN Isoform 1 of Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase OS=Bos taurus OX=9913 GN=ADPRM PE=3 SV=1 CANONICAL=A0ABI0NL40-1" }, "locus": { "chromosome": "19", "start_pos": 29674848, "end_pos": 29668710, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136872.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136872.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105638.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105638.1" } ] } }, { "isoform_ac": "A0ABI0P0Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40/entry#A0ABI0P0Y4-1", "sequence": { "sequence": "MRFCDSESYLEVMDYKPEPELLSESSERLFSFGVIADIQYADLEDGYNFQGNRRRYYRHSLLHLQGAIEHWNQERSPPRCVLQLGDIIDGYNAQYKASEKSLERVMNTFQMLRVPVHHTWGNHEFYNFSRDYLTNSKLNTKFLEDQIAHHPETVPSEDYYAYHFVPFPKFRFILLDAYDMSVLGVDQSSPKYQQCLKILREHNPNTELNSPQGLREPQFVQFNGGFSPEQLNWLNAVLTFSDRNQEKVVIVSHLPIYPEASDSVCLAWNYRDALAVIWSHKCVVCFFAGHTHDGGYSEDPYGVHHVNIEGVIETAPDSQAFGTVHVYPDKMMLEGRGRVPHRIMNYRKE", "length": 349, "header": "tr|A0ABI0P0Y4-1|A0ABI0P0Y4_BOVIN Computationally mapped isoform of Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase OS=Bos taurus OX=9913 GN=ADPRM PE=3 SV=1 CANONICAL=A0ABI0NL40-1" }, "locus": { "chromosome": "19", "start_pos": 29674848, "end_pos": 29667331, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141842.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141842.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104540.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104540.1" } ] } }, { "isoform_ac": "A0ABI0P3X7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40/entry#A0ABI0P3X7-1", "sequence": { "sequence": "MDYKPEPELLSESSERLFSFGVIADIQYADLEDGYNFQGNRRRYYRHSLLHLQGAIEHWNQERSPPRCVLQLGDIIDGYNAQYKASEKSLERVMNTFQMLRVPVHHTWGNHEFYNFSRDYLTNSKLNTKFLEDQIAHHPETVPSEDYYAYHFVPFPKFRFILLDAYDMSVLGVDQSSPKYQQCLKILREHNPNTELNSPQGLREPQFVQFNGGFSPEQLNWLNAVLTFSDRNQEKVVIVSHLPIYPEASDSVCLAWNYRDALAVIWSHKCVVCFFAGHTHDGGYSEDPYGVHHVNIEGVIETAPDSQAFGTVHVYPDKMMLEGRGRVPHRIMNYRKE", "length": 337, "header": "tr|A0ABI0P3X7-1|A0ABI0P3X7_BOVIN Computationally mapped isoform of Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase OS=Bos taurus OX=9913 GN=ADPRM PE=3 SV=1 CANONICAL=A0ABI0NL40-1" }, "locus": { "chromosome": "19", "start_pos": 29674848, "end_pos": 29669996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138386.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138386.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106217.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106217.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:534038", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534038", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40" } ], "pmid": "" }, { "name": "ADP-ribose diphosphatase activity", "id": "GO:0047631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047631", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40" } ], "pmid": "" }, { "name": "CDP-glycerol diphosphatase activity", "id": "GO:0047734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047734", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NL40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10412", "name": "", "equation": "ADP-D-ribose + H2O = D-ribose 5-phosphate + AMP + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A7YY53-1", "A0AAA9TPZ1-1", "F6RY34-1", "Q05B60-1", "A0ABI0NL40-1" ], "evidence": [ { "id": "10412", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10412" } ] }, { "id": "21692", "name": "", "equation": "CDP-glycerol + H2O = sn-glycerol 3-phosphate + CMP + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A7YY53-1", "A0ABI0NL40-1" ], "evidence": [ { "id": "21692", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21692" } ] }, { "id": "32487", "name": "", "equation": "CDP-choline + H2O = phosphocholine + CMP + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A7YY53-1", "A0ABI0NL40-1" ], "evidence": [ { "id": "32487", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32487" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9TPZ1", "gene_name": "NUDT5", "activity": [ { "ec_number": "3.6.1.58", "activity": "8-oxo-GDP + H2O = 8-oxo-GMP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TPZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPZ1" } ] }, { "ec_number": "3.6.1.13", "activity": "ADP-D-ribose + H2O = D-ribose 5-phosphate + AMP + 2 H(+).", "evidence": [ { "id": "A0AAA9TPZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPZ1" } ] }, { "ec_number": "2.7.7.96", "activity": "D-ribose 5-phosphate + ATP + H(+) = ADP-D-ribose + diphosphate.", "evidence": [ { "id": "A0AAA9TPZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPZ1" } ] }, { "ec_number": "3.6.1.58", "activity": "", "evidence": [ { "id": "A0AAA9TPZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPZ1" } ] }, { "ec_number": "3.6.1.13", "activity": "", "evidence": [ { "id": "A0AAA9TPZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPZ1" } ] }, { "ec_number": "2.7.7.96", "activity": "", "evidence": [ { "id": "A0AAA9TPZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPZ1" } ] } ] }, { "uniprot_ac": "A0ABI0NL40", "gene_name": "ADPRM", "activity": [ { "ec_number": "3.6.1.13", "activity": "ADP-D-ribose + H2O = D-ribose 5-phosphate + AMP + 2 H(+).", "evidence": [ { "id": "A0ABI0NL40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40" } ] }, { "ec_number": "3.6.1.16", "activity": "CDP-glycerol + H2O = sn-glycerol 3-phosphate + CMP + 2 H(+).", "evidence": [ { "id": "A0ABI0NL40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40" } ] }, { "ec_number": "3.6.1.53", "activity": "ADP-D-ribose + H2O = D-ribose 5-phosphate + AMP + 2 H(+).", "evidence": [ { "id": "A0ABI0NL40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40" } ] }, { "ec_number": "3.6.1.13", "activity": "", "evidence": [ { "id": "A0ABI0NL40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40" } ] }, { "ec_number": "3.6.1.53", "activity": "", "evidence": [ { "id": "A0ABI0NL40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40" } ] }, { "ec_number": "3.6.1.16", "activity": "", "evidence": [ { "id": "A0ABI0NL40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL40" } ] } ] }, { "uniprot_ac": "A7YY53", "gene_name": "ADPRM", "activity": [ { "ec_number": "3.6.1.16", "activity": "CDP-glycerol + H2O = sn-glycerol 3-phosphate + CMP + 2 H(+).", "evidence": [ { "id": "A7YY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YY53" } ] }, { "ec_number": "3.6.1.53", "activity": "ADP-D-ribose + H2O = D-ribose 5-phosphate + AMP + 2 H(+).", "evidence": [ { "id": "A7YY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YY53" } ] }, { "ec_number": "3.6.1.16", "activity": "", "evidence": [ { "id": "A7YY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YY53" } ] }, { "ec_number": "3.6.1.53", "activity": "", "evidence": [ { "id": "A7YY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YY53" } ] } ] }, { "uniprot_ac": "F6RY34", "gene_name": "NUDT9", "activity": [ { "ec_number": "3.6.1.13", "activity": "ADP-D-ribose + H2O = D-ribose 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"MGSRLLCWVTLCVLGVGHTRAGVVSQSPGYRVAGRGQTVNFRCDPIPGHQVLYWYRQMLGQGLEYLTYFQGKEEPDKSGMPKNRFSAERPESTYSYLKIQPVEPEDSALYLCASSPTTARHSHLLPVHKPLRAHFSSWFPEMPEKGATCSSLCRGSKWIWGFSCSDSWRSENYL", "length": 174, "header": "tr|A0ABI0NLY6-1|A0ABI0NLY6_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NLY6-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NLY6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLY6/entry#A0ABI0NLY6-1", "sequence": { "sequence": "MGSRLLCWVTLCVLGVGHTRAGVVSQSPGYRVAGRGQTVNFRCDPIPGHQVLYWYRQMLGQGLEYLTYFQGKEEPDKSGMPKNRFSAERPESTYSYLKIQPVEPEDSALYLCASSPTTARHSHLLPVHKPLRAHFSSWFPEMPEKGATCSSLCRGSKWIWGFSCSDSWRSENYL", "length": 174, "header": "tr|A0ABI0NLY6-1|A0ABI0NLY6_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NLY6-1" }, "locus": { "chromosome": "4", "start_pos": 105744304, "end_pos": 105743549, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146720.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146720.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105937.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105937.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NLY6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLY6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NLY6", "database": "UniProtKB", "url": 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"tr|A0ABI0NM07-1|A0ABI0NM07_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NM07-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NM07-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM07/entry#A0ABI0NM07-1", "sequence": { "sequence": "MNHLHSHSSAVQPGKVNMMSLSVLGLRMLFAKSVAVNFLLTAKLFFF", "length": 47, "header": "tr|A0ABI0NM07-1|A0ABI0NM07_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NM07-1" }, "locus": { "chromosome": "10", "start_pos": 22352897, "end_pos": 22352757, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151452.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151452.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106328.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106328.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NM09-1", "uniprot_ac": "A0ABI0NM09", "uniprot_id": "A0ABI0NM09_BOVIN", "mass": { "chemical_mass": 35393.0, "monoisotopic_mass": 35393.0 }, "refseq": { "ac": "NP_001377525", "name": "olfactory receptor family 4 subfamily F member 14J", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377525" }, "gene_names": [ { "name": "OR4F14J", "type": "recommended", "evidence": [ { "id": "A0ABI0NM09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM09" } ] }, { "name": "OR4F14J", "type": "synonym", "evidence": [ { "id": "NP_001377525", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377525" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NM09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM09/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4F3/4F16/4F29", "type": "synonym", "evidence": [ { "id": "NP_001377525", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377525" } ] }, { "name": "olfactory receptor family 4 subfamily F member 14J", "type": "synonym", "evidence": [ { "id": "NP_001377525", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377525" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377525", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377525" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM09", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM09#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM09", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM09" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4F14J", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM09", "locus": {} } ], "crossref": [ { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "788790", "url": "https://www.ncbi.nlm.nih.gov/gene/788790", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377525", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377525", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NM09", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM09-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYGANQSVVSEFVFLGLTNSWEIQLLLFVFSSSFYIASTMGNLLILLTVISDPHLHSSMYFLLANLSFIDLGFSTIFSPKMIYDLFRKHKVMSFSGCITQIFFIHIIGGVEVVLLIAMAFDRYVAICKPLHYLTIMSPRMCVFFIVAAWIIGLIHSVVQLACMVNLPFCGPNVLDSFYCDLPQLIKLACTDTYQLKFMVTANSGLISVGSFFILIISYIIIILTVQKQSSAGSSKALSTLSAHITVVVLFFSPLMFFYIWPFSSSHLGKFLAIFDAVLTPFLNPVIYTFRNHEMRVAMRRVCKQLVNYRRSLK", "length": 313, "header": "tr|A0ABI0NM09-1|A0ABI0NM09_BOVIN 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"evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM09", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NM09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM09" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NM10-1", "uniprot_ac": "A0ABI0NM10", "uniprot_id": "A0ABI0NM10_BOVIN", "mass": { "chemical_mass": 18767.0, "monoisotopic_mass": 18767.0 }, "refseq": {}, "gene_names": [ { "name": "LOC132343240", "type": "recommended", "evidence": [ { "id": "A0ABI0NM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM10" } ] } ], "protein_names": [ { "name": "Dynein light chain Tctex-type 3", "type": "recommended", "evidence": [ { "id": "A0ABI0NM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM10/entry#names_and_taxonomy" } ] }, { "name": "T-complex-associated testis-expressed 1-like", "type": "synonym", "evidence": [ { "id": "A0ABI0NM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM10/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM10", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM10#function" }, { "database": "UniProtKB", "id": "ARBA00037393", "url": "https://www.uniprot.org/uniprotkb/ARBA00037393#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM10", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM10" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132343240", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM10", "locus": {} } ], "crossref": [ { "id": "cd21463", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21463", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005334", "url": 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDYCLERQKKKKQRHREILRNKNCSDRRFLGEREEVRNDLRRLGATMEEYHRPCDEVGFNADEAHNIVQECIDGVLGGEDYNQNNIDQWTANIVEQSLAHLVKLGKAHKYIVTCAVVQRSPYGFHTASSCFWDTTSDGTCTVRWENRTMNCIVNVFAIAIVL", "length": 162, "header": "tr|A0ABI0NM10-1|A0ABI0NM10_BOVIN Isoform 1 of Dynein light chain Tctex-type 3 OS=Bos taurus OX=9913 GN=LOC132343240 PE=3 SV=1 CANONICAL=A0ABI0NM10-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NM10-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM10/entry#A0ABI0NM10-1", "sequence": { "sequence": "MDYCLERQKKKKQRHREILRNKNCSDRRFLGEREEVRNDLRRLGATMEEYHRPCDEVGFNADEAHNIVQECIDGVLGGEDYNQNNIDQWTANIVEQSLAHLVKLGKAHKYIVTCAVVQRSPYGFHTASSCFWDTTSDGTCTVRWENRTMNCIVNVFAIAIVL", "length": 162, "header": "tr|A0ABI0NM10-1|A0ABI0NM10_BOVIN Isoform 1 of Dynein light chain Tctex-type 3 OS=Bos taurus OX=9913 GN=LOC132343240 PE=3 SV=1 CANONICAL=A0ABI0NM10-1" }, "locus": { "chromosome": "20", "start_pos": 40000396, "end_pos": 39999911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154691.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154691.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104674.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104674.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM10", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM10" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM10", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM10" } ], "pmid": "" }, { "name": "kinetochore", "id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NM11-1", "uniprot_ac": "A0ABI0NM11", "uniprot_id": "A0ABI0NM11_BOVIN", "mass": { "chemical_mass": 32332.0, "monoisotopic_mass": 32332.0 }, "refseq": { "ac": "XP_059739800", "name": "transcription factor E2F6-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739800" }, "gene_names": [ { "name": "LOC132344338", "type": "recommended", "evidence": [ { "id": "A0ABI0NM11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM11" } ] }, { "name": "LOC132344338", "type": "synonym", "evidence": [ { "id": "XP_059739800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739800" } ] } ], "protein_names": [ { "name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NM11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM11/entry#names_and_taxonomy" } ] }, { "name": "transcription factor E2F6-like", "type": "synonym", "evidence": [ { "id": "XP_059739800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739800" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NM11", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM11" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132344338", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM11", "locus": {} } ], "crossref": [ { "id": "cd14660", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14660", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "132344338", "url": "https://www.ncbi.nlm.nih.gov/gene/132344338", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015633", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015633", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": 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May also play important roles in cell morphology and locomotion.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LIB4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIB4#function" }, { "database": "UniProtKB", "id": "ARBA00024757", "url": "https://www.uniprot.org/uniprotkb/ARBA00024757#function" }, { "database": "UniProtKB", "id": "F1N789", "url": "https://www.uniprot.org/uniprotkb/F1N789#function" }, { "database": "UniProtKB", "id": "A0ABI0NJJ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJJ0#function" }, { "database": "UniProtKB", "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6#function" }, { "database": "UniProtKB", "id": "A0ABI0P2J8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2J8#function" }, { "database": "UniProtKB", "id": "A0ABI0P303", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P303#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "VCL", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6", "locus": { "chromosome": "28", "start_pos": 29989469, "end_pos": 29878003, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021879", "url": "https://www.ensembl.org/id/ENSBTAG00000021879" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021879", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021879", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "783645", "url": "https://www.ncbi.nlm.nih.gov/gene/783645", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000633", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000633", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:783645", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783645", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LIB4", "url": "https://www.orthodb.org/?gene=A0A3Q1LIB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N789", "url": "https://www.orthodb.org/?gene=F1N789", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46180", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46180", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LIB4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LIB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJJ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNT6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2J8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2J8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2J8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P303", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P303", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P303-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P303-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N789", "url": "https://www.uniprot.org/uniprotkb/F1N789", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N789-1", "url": "https://www.uniprot.org/uniprotkb/F1N789-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKVMKSWNDPRSAVEEVQPCLTYSCSHEFFPNCVLSGLDDCLGGYAPPRGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ", "length": 1181, "header": "tr|A0ABI0NNT6-1|A0ABI0NNT6_BOVIN Isoform 1 of Vinculin OS=Bos taurus OX=9913 GN=VCL PE=1 SV=1 CANONICAL=A0ABI0NNT6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LIB4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6/entry#A0A3Q1LIB4-1", "sequence": { "sequence": "MGKEVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ", "length": 1014, "header": "tr|A0A3Q1LIB4-1|A0ABI0NNT6_BOVIN Computationally mapped isoform of Vinculin OS=Bos taurus OX=9913 GN=VCL PE=1 SV=1 CANONICAL=A0ABI0NNT6-1" }, "locus": { "chromosome": "28", "start_pos": 29987539, "end_pos": 29878234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079898.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079898.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058727.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058727.1" } ] } }, { "isoform_ac": "A0ABI0NJJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6/entry#A0ABI0NJJ0-1", "sequence": { "sequence": "MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ", "length": 1134, "header": "tr|A0ABI0NJJ0-1|A0ABI0NNT6_BOVIN Computationally mapped isoform of Vinculin OS=Bos taurus OX=9913 GN=VCL PE=1 SV=1 CANONICAL=A0ABI0NNT6-1" }, "locus": { "chromosome": "28", "start_pos": 29987539, "end_pos": 29877008, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138651.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138651.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104314.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104314.1" } ] } }, { "isoform_ac": "A0ABI0NNT6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6/entry#A0ABI0NNT6-1", "sequence": { "sequence": "MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKVMKSWNDPRSAVEEVQPCLTYSCSHEFFPNCVLSGLDDCLGGYAPPRGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ", "length": 1181, "header": "tr|A0ABI0NNT6-1|A0ABI0NNT6_BOVIN Isoform 1 of Vinculin OS=Bos taurus OX=9913 GN=VCL PE=1 SV=1 CANONICAL=A0ABI0NNT6-1" }, "locus": { "chromosome": "28", "start_pos": 29987539, "end_pos": 29877008, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141929.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141929.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107536.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107536.1" } ] } }, { "isoform_ac": "A0ABI0P2J8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6/entry#A0ABI0P2J8-1", "sequence": { "sequence": "MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ", "length": 1066, "header": "tr|A0ABI0P2J8-1|A0ABI0P2J8_BOVIN Computationally mapped isoform of Vinculin OS=Bos taurus OX=9913 GN=VCL PE=1 SV=1 CANONICAL=A0ABI0NNT6-1" }, "locus": { "chromosome": "28", "start_pos": 29987539, "end_pos": 29877008, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143162.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143162.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104667.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104667.1" } ] } }, { "isoform_ac": "A0ABI0P303-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6/entry#A0ABI0P303-1", "sequence": { "sequence": "MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPASCVTIVIQQDYIPNLVSDLLFIFTAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRASRGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ", "length": 1119, "header": "tr|A0ABI0P303-1|A0ABI0P303_BOVIN Computationally mapped isoform of Vinculin OS=Bos taurus OX=9913 GN=VCL PE=1 SV=1 CANONICAL=A0ABI0NNT6-1" }, "locus": { "chromosome": "28", "start_pos": 29987539, "end_pos": 29877008, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137813.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137813.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105935.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105935.1" } ] } }, { "isoform_ac": "F1N789-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6/entry#F1N789-1", "sequence": { "sequence": "MGTELGSLGHMMQPLEARVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ", "length": 1004, "header": "tr|F1N789-1|A0ABI0NNT6_BOVIN Computationally mapped isoform of Vinculin OS=Bos taurus OX=9913 GN=VCL PE=1 SV=2 CANONICAL=A0ABI0NNT6-1" }, "locus": { "chromosome": "28", "start_pos": 29987539, "end_pos": 29925096, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061210.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061210.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053644.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053644.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:783645", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783645", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6" } ], "pmid": "" }, { "name": "podosome", "id": "GO:0002102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002102", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6" } ], "pmid": "" }, { "name": "myofibril", "id": "GO:0030016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030016", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6" } ], "pmid": "" }, { "name": "cell-cell contact zone", "id": "GO:0044291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044291", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNT6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1125, "end_pos": 1127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1125, "end_pos": 1127 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 288, "end_pos": 290 }, { "start_pos": 635, "end_pos": 637 }, { "start_pos": 654, "end_pos": 656 }, { "start_pos": 807, "end_pos": 809 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NMW4-1", "uniprot_ac": "A0ABI0NMW4", "uniprot_id": "A0ABI0NMW4_BOVIN", "mass": { "chemical_mass": 138695.0, "monoisotopic_mass": 138695.0 }, "refseq": {}, "gene_names": [ { "name": "EHMT2", "type": "recommended", "evidence": [ { "id": "A0ABI0NMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" } ] } ], "protein_names": [ { "name": "[histone H3]-lysine(9) N-methyltransferase", "type": "recommended", "evidence": [ { "id": "A0ABI0NMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.367", "type": "synonym", "evidence": [ { "id": "A0ABI0NMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EHMT2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4", "locus": { "chromosome": "23", "start_pos": 27480387, "end_pos": 27467004, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005676", "url": "https://www.ensembl.org/id/ENSBTAG00000005676" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005676", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005676", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10533", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10533", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20905", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20905", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514062", "url": "https://www.ncbi.nlm.nih.gov/gene/514062", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007728", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007728", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514062", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514062", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR46307", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46307", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46307:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46307:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21533", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21533", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LSA6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M4W7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M4W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4W7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMW4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMW4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGLPRGRGLMRARGRGRAAPPGSRGRGRGGAHRGRGRPRSLLSLPRAQASWAPQLPTGLTSPPIPCVPSQGEAPAEMGALVLEKEPRGATERVHGSLGDTSRSEETLPKANPDSLETAGPSSPASVTVTVGDEGADTPVGATPLIGDEPENLEGDGDLHGGRILLGHATKSFPSSPSKGGACPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAPAAGPEPPPATASPEGQPKVHRARKTMSKPGNGQPPVPEKRPPEVQHFRMSDDVHSLGKVTSDVAKRRKLNSGGGLSEELASTRSSGEVTLEKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALAEQLSEEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKRRKREPPRAKEPRGVNGVGSSGPSEYMEVPLGSLELPSEGTLSPNHAGVSNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKCMATESVDGELSGCNAAILKRETMRPSSRVALMVLCETHRARMVKHHCCPGCGYFCTAGTFLECHPDFRVAHRFHKACVSQLNGMVFCPHCGEDASEAQEVTIPRGDGVTPPAGTAAPAPPPLAQDAPGRADTSQPSARMRGQGEPRRPPCDPLADTIDSSGPSLTLPNGGCLSAVGLPPGPGREALEKALVIQESERRKKLRFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRAGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSRLARLDPHPELLPELSSLPPVNP", "length": 1268, "header": "tr|A0ABI0NMW4-1|A0ABI0NMW4_BOVIN Isoform 1 of [histone H3]-lysine(9) N-methyltransferase OS=Bos taurus OX=9913 GN=EHMT2 PE=4 SV=1 CANONICAL=A0ABI0NMW4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LSA6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4/entry#A0A3Q1LSA6-1", "sequence": { "sequence": "MAAAAGAAAAAAAEGEAPAEMGALVLEKEPRGATERVHGSLGDTSRSEETLPKANPDSLETAGPSSPASVTVTVGDEGADTPVGATPLIGDEPENLEGDGDLHGGRILLGHATKSFPSSPSKGGACPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAPAAGPEPPPATASPEGQPKVHRARKTMSKPGNGQPPVPEKRPPEVQHFRMSDDVHSLGKVTSDVAKRRKLNSGGGLSEELASTRSSGEVTLEKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALAEQLSEEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKRRKREPPRAKEPRGVNGVGSSGPSEYMEVPLGSLELPSEGTLSPNHAGVSNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKCMATESVDGELSGCNAAILKRETMRPSSRVALMVLCETHRARMVKHHCCPGCGYFCTAGTFLECHPDFRVAHRFHKACVSQLNGMVFCPHCGEDASEAQEVTIPRGDGVTPPAGTAAPAPPPLAQDAPGRADTSQPSARMRGQGEPRRPPCDPLADTIDSSGPSLTLPNGGCLSAVGLPPGPGREALEKALVIQESERRKKLRFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRAGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSRLARLDPHPELLPELSSLPPVNP", "length": 1211, "header": "tr|A0A3Q1LSA6-1|A0ABI0NMW4_BOVIN Computationally mapped isoform of [histone H3]-lysine(9) N-methyltransferase OS=Bos taurus OX=9913 GN=EHMT2 PE=4 SV=1 CANONICAL=A0ABI0NMW4-1" }, "locus": { "chromosome": "23", "start_pos": 27480040, "end_pos": 27467203, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079107.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079107.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063225.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063225.1" } ] } }, { "isoform_ac": "A0A3Q1M4W7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4/entry#A0A3Q1M4W7-1", "sequence": { "sequence": "MRGLPRGRGLMRARGRGRAAPPGSRGRGRGGAHRGRGRPRSLLSLPRAQASWAPQLPTGLTSPPIPCVPSQGEAPAEMGALVLEKEPRGATERVHGSLGDTSRSEETLPKANPDSLETAGPSSPASVTVTVGDEGADTPVGATPLIGDEPENLEGDGDLHGGRILLGHATKSFPSSPSKGGACPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAPAAGPEPPPATASPEGQPKVHRARKTMSKPGNGQPPVPEKRPPEVQHFRMSDDVHSLGKVTSDVAKRRKLNSGGGLSEELASTRSSGEVTLEKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALAEQLSEEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKRRKREPPRAKEPRGVSNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKCMATESVDGELSGCNAAILKRETMRPSSRVALMVLCETHRARMVKHHCCPGCGYFCTAGTFLECHPDFRVAHRFHKACVSQLNGMVFCPHCGEDASEAQEVTIPRGDGVTPPAGTAAPAPPPLAQDAPGRADTSQPSARMRGQGEPRRPPCDPLADTIDSSGPSLTLPNGGCLSAVGLPPGPGREALEKALVIQESERRKKLRFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRAGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSRLARLDPHPELLPELSSLPPVNP", "length": 1234, "header": "tr|A0A3Q1M4W7-1|A0ABI0NMW4_BOVIN Computationally mapped isoform of [histone H3]-lysine(9) N-methyltransferase OS=Bos taurus OX=9913 GN=EHMT2 PE=4 SV=3 CANONICAL=A0ABI0NMW4-1" }, "locus": { "chromosome": "23", "start_pos": 27480040, "end_pos": 27467678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067355.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067355.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065284.3", "url": "https://www.ensembl.org/id/ENSBTAP00000065284.3" } ] } }, { "isoform_ac": "A0A3Q1MQW5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4/entry#A0A3Q1MQW5-1", "sequence": { "sequence": "MAAAAGAAAAAAAEGEAPAEMGALVLEKEPRGATERGHATKSFPSSPSKGGACPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAPAAGPEPPPATASPEGQPKVHRARKTMSKPGNGQPPVPEKRPPEVQHFRMSDDVHSLGKVTSDVAKRRKLNSGGGLSEELASTRSSGEVTLEKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALAEQLSEEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKRRKREPPRAKEPRGVNGVGSSGPSEYMEVPLGSLELPSEGTLSPNHAGVSNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKCMATESVDGELSGCNAAILKRETMRPSSRVALMVLCETHRARMVKHHCCPGCGYFCTAGTFLECHPDFRVAHRFHKACVSQLNGMVFCPHCGEDASEAQEVTIPRGDGVTPPAGTAAPAPPPLAQDAPGRADTSQPSARMRGQGEPRRPPCDPLADTIDSSGPSLTLPNGGCLSAVGLPPGPGREALEKALVIQESERRKKLRFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRAGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSRLARLDPHPELLPELSSLPPVNP", "length": 1138, "header": "tr|A0A3Q1MQW5-1|A0ABI0NMW4_BOVIN Computationally mapped isoform of [histone H3]-lysine(9) N-methyltransferase OS=Bos taurus OX=9913 GN=EHMT2 PE=4 SV=1 CANONICAL=A0ABI0NMW4-1" }, "locus": { "chromosome": "23", "start_pos": 27480040, "end_pos": 27467203, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074923.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074923.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074031.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074031.1" } ] } }, { "isoform_ac": "A0ABI0NMW4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4/entry#A0ABI0NMW4-1", "sequence": { "sequence": "MRGLPRGRGLMRARGRGRAAPPGSRGRGRGGAHRGRGRPRSLLSLPRAQASWAPQLPTGLTSPPIPCVPSQGEAPAEMGALVLEKEPRGATERVHGSLGDTSRSEETLPKANPDSLETAGPSSPASVTVTVGDEGADTPVGATPLIGDEPENLEGDGDLHGGRILLGHATKSFPSSPSKGGACPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAPAAGPEPPPATASPEGQPKVHRARKTMSKPGNGQPPVPEKRPPEVQHFRMSDDVHSLGKVTSDVAKRRKLNSGGGLSEELASTRSSGEVTLEKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALAEQLSEEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKRRKREPPRAKEPRGVNGVGSSGPSEYMEVPLGSLELPSEGTLSPNHAGVSNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKCMATESVDGELSGCNAAILKRETMRPSSRVALMVLCETHRARMVKHHCCPGCGYFCTAGTFLECHPDFRVAHRFHKACVSQLNGMVFCPHCGEDASEAQEVTIPRGDGVTPPAGTAAPAPPPLAQDAPGRADTSQPSARMRGQGEPRRPPCDPLADTIDSSGPSLTLPNGGCLSAVGLPPGPGREALEKALVIQESERRKKLRFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRAGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSRLARLDPHPELLPELSSLPPVNP", "length": 1268, "header": "tr|A0ABI0NMW4-1|A0ABI0NMW4_BOVIN Isoform 1 of [histone H3]-lysine(9) N-methyltransferase OS=Bos taurus OX=9913 GN=EHMT2 PE=4 SV=1 CANONICAL=A0ABI0NMW4-1" }, "locus": { "chromosome": "23", "start_pos": 27480040, "end_pos": 27467678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148833.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148833.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106882.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106882.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:514062", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514062", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" } ], "pmid": "" }, { "name": "histone H3K9 monomethyltransferase activity", "id": "GO:0140948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140948", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" } ], "pmid": "" }, { "name": "histone H3 methyltransferase activity", "id": "GO:0140938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140938", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1164, "end_pos": 1166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" }, { "id": "PS50867", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50867" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pre-SET", "eco_id": "ECO_0000259", "start_pos": 1030, "end_pos": 1093, "start_aa": "Gln", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW4" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 1096, "end_pos": 1213, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.367", "ec_name": "L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "2.1.1.367", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.367" }, { "id": "2.1.1.367", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.367" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 130 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1025, "end_pos": 1027 }, { "start_pos": 1164, "end_pos": 1166 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 467, "end_pos": 469 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"A0AAA9TLZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXI2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXI2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0L3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0L3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1D1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1D1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT56", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT56-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MV61", "url": "https://www.uniprot.org/uniprotkb/F1MV61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MV61-1", "url": "https://www.uniprot.org/uniprotkb/F1MV61-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAFGIATGGSNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYALSHVAKYFDQEMLNVRNLNYSSSRTLLFQRFSVIFTDALFVYAVHECCKCIDGKKAGKELTEKPKFILSALLLWNFGLLIVDHIHFQYNGFLSGLMLLSIARFFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKQDGSIRWNSFSFVRLISLGLIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYSAFDKVLSVIGLELKLLDPNKIPKASMTSGLVQQFQHTVLPSVTPLATFICTLIAMLPSVFCLWCKPQGPRGFLRCLILCALSSFMFGWHVHEKAILLAVLPMSLLSVGKAVDASIFLILTTTGHYSLFPLLFTAPELPIKIILMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVFCEFVFPFTSWNLKYPFIPLLLTSVYCAVGITYAWLKLYVSVLIDPPVGKTKKQ", "length": 526, "header": "tr|A0ABI0NT56-1|A0ABI0NT56_BOVIN Isoform 1 of Alpha-1,3-glucosyltransferase OS=Bos taurus OX=9913 GN=ALG8 PE=3 SV=1 CANONICAL=A0ABI0NT56-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RWQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56/entry#A0AAA9RWQ6-1", "sequence": { "sequence": "MAAFGIATGGSNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYALSHVAKYFDQEMLNVRNLNYSSSRTLLFQRFSVIFTDALFVYAVHECCKCIDGKKAGKELTEKPKFILSALLLWNFGLLIVDHIHFQYNGFLSGLMLLSIARFFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKQDGSIRWNSFSFVRLISLGLIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYSAFDKVLSVIGLELKLLDPNKIPKASMTSGLVQQFQHTVLPSVTPLATFICTLIAMLKRKASF", "length": 352, "header": "tr|A0AAA9RWQ6-1|A0ABI0NT56_BOVIN Computationally mapped isoform of Alpha-1,3-glucosyltransferase OS=Bos taurus OX=9913 GN=ALG8 PE=3 SV=1 CANONICAL=A0ABI0NT56-1" }, "locus": { "chromosome": "29", "start_pos": 17971643, "end_pos": 17944198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094838.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094838.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075550.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075550.1" } ] } }, { "isoform_ac": "A0AAA9T3E0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56/entry#A0AAA9T3E0-1", "sequence": { "sequence": "MAAFGIATGGSNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYALSHVAKYFDQEMLNVRNLNYSSSRTLLFQRFSVIFTDALFVYAVHECCKCIDGKKAGKELTEKPKFILSALLLWNFGLLIVDHIHFQYNGFLSGLMLLSIARFFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKQDGSIRWNSFSFVRLISLGLIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYSAFDKVLSVIGPRGFLRCLILCALSSFMFGWHVHEKAILLAVLPMSLLSVGKAVDASIFLILTTTGHYSLFPLLFTAPELPIKIILMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVFCEFVFPFTSWNLKYPFIPLLLTSVYCAVGITYAWLKLYVSVLIDPPVGKTKKQ", "length": 468, "header": "tr|A0AAA9T3E0-1|A0ABI0NT56_BOVIN Computationally mapped isoform of Alpha-1,3-glucosyltransferase OS=Bos taurus OX=9913 GN=ALG8 PE=3 SV=1 CANONICAL=A0ABI0NT56-1" }, "locus": { "chromosome": "29", "start_pos": 17971854, "end_pos": 17944198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106467.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106467.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090213.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090213.1" } ] } }, { "isoform_ac": "A0AAA9TLZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56/entry#A0AAA9TLZ2-1", "sequence": { "sequence": "MAAFGIATGGSNWFSALALGVTLLKCLLIPTYSRTLLFQRFSVIFTDALFVYAVHECCKCIDGKKAGKELTEKPKFILSALLLWNFGLLIVDHIHFQYNGFLSGLMLLSIARFFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKQDGSIRWNSFSFVRLISLGLIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYSAFDKVLSVIGLELKLLDPNKIPKASMTSGLVQQFQHTVLPSVTPLATFICTLIAMLPSVFCLWCKPQGPRGFLRCLILCALSSFMFGWHVHEKAILLAVLPMSLLSVGKAVDASIFLILTTTGHYSLFPLLFTAPELPIKIILMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVFCEFVFPFTSWNLKYPFIPLLLTSVYCAVGITYAWLKLYVSVLIDPPVGKTKKQ", "length": 459, "header": "tr|A0AAA9TLZ2-1|A0ABI0NT56_BOVIN Computationally mapped isoform of Alpha-1,3-glucosyltransferase OS=Bos taurus OX=9913 GN=ALG8 PE=3 SV=1 CANONICAL=A0ABI0NT56-1" }, "locus": { "chromosome": "29", "start_pos": 17971854, "end_pos": 17944198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105865.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105865.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098260.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098260.1" } ] } }, { "isoform_ac": "A0AAA9TXI2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56/entry#A0AAA9TXI2-1", "sequence": { "sequence": "MAAFGIATGGSNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYALSHVAKYFDQEMLNVRNLNYSSSRTLLFQRFSVIFTDALFVYAVHECCKCIDGKKAGKELTEKPKFILSALLLWNFGLLIVDHIHFQYNGFLSGLMLLSIARFFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKQDGSIRWNSFSFVRLISLGLIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYSAFDKVLSVIGLELKLLDPNKIPKASMTSGLVQQFQHTVLPSVTPLATFICTLIAMLPSVFCLWCKPQGPRGFLRCLILCALSSFMFGWHVHEKAILLAVLPMSLLSVGKAVDASIFLILTTTGHYSLFPLLFTAPELPIKIILMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVFCEFVFPFTSWNLKS", "length": 487, "header": "tr|A0AAA9TXI2-1|A0ABI0NT56_BOVIN Computationally mapped isoform of Alpha-1,3-glucosyltransferase OS=Bos taurus OX=9913 GN=ALG8 PE=3 SV=1 CANONICAL=A0ABI0NT56-1" }, "locus": { "chromosome": "29", "start_pos": 17977282, "end_pos": 17944198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123951.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123951.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101920.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101920.1" } ] } }, { "isoform_ac": "A0AAA9U0L3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56/entry#A0AAA9U0L3-1", "sequence": { "sequence": "MAAFGIATGGSNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYALSHVAKYFDQEMLNVRNLNYSSSRTLLFQRFSVIFTDALFVYAVHECCKCIDGKKAGKELTEKPKFILSALLLWNFGLLIVDHIHFQYNGFLSGLMLLSIARFFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKQDGSIRWNSFSFVRLISLGLIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYSAFDKVLSVIGLELKLLDPNKIPKASMTSGLVQQFQHTVLPSVTPLATFICTLIAMLPSVFCLWCKPQGPRGFLRCLILCALSSFMFGWHVHEKAILLAVLPMSLLSVGKAVDASIFLILTTTGHYSLFPLLFTAPEKKSLFLIGWKLSTSLAWDLWKSSVNLYSLSPPGT", "length": 460, "header": "tr|A0AAA9U0L3-1|A0ABI0NT56_BOVIN Computationally mapped isoform of Alpha-1,3-glucosyltransferase OS=Bos taurus OX=9913 GN=ALG8 PE=3 SV=1 CANONICAL=A0ABI0NT56-1" }, "locus": { "chromosome": "29", "start_pos": 17971729, "end_pos": 17944198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105872.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105872.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103493.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103493.1" } ] } }, { "isoform_ac": "A0AAA9U1D1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56/entry#A0AAA9U1D1-1", "sequence": { "sequence": "MAAFGIATGGSNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYALSHVAKYFDQEMLNVRNLNYSSSRTLLFQRFSVIFTDALFVYAVHECCKCIDGKKAGKELTEKPKFILSALLLWNFGLLIVDHIHFQYNGFLSGLMLLSIARFFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKQDGSIRWNSFSFVRLISLGLIVFLVSALSLGPFLALPSVFCLWCKPQGPRGFLRCLILCALSSFMFGWHVHEKAILLAVLPMSLLSVGKAVDASIFLILTTTGHYSLFPLLFTAPELPIKIILMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVFCEFVFPFTSWNLKYPFIPLLLTSVYCAVGITYAWLKLYVSVLIDPPVGKTKKQ", "length": 439, "header": "tr|A0AAA9U1D1-1|A0ABI0NT56_BOVIN Computationally mapped isoform of Alpha-1,3-glucosyltransferase OS=Bos taurus OX=9913 GN=ALG8 PE=3 SV=1 CANONICAL=A0ABI0NT56-1" }, "locus": { "chromosome": "29", "start_pos": 17971854, "end_pos": 17944198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131008.2", "url": "https://www.ensembl.org/id/ENSBTAT00000131008.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103881.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103881.1" } ] } }, { "isoform_ac": "A0ABI0NT56-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56/entry#A0ABI0NT56-1", "sequence": { "sequence": "MAAFGIATGGSNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYALSHVAKYFDQEMLNVRNLNYSSSRTLLFQRFSVIFTDALFVYAVHECCKCIDGKKAGKELTEKPKFILSALLLWNFGLLIVDHIHFQYNGFLSGLMLLSIARFFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKQDGSIRWNSFSFVRLISLGLIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYSAFDKVLSVIGLELKLLDPNKIPKASMTSGLVQQFQHTVLPSVTPLATFICTLIAMLPSVFCLWCKPQGPRGFLRCLILCALSSFMFGWHVHEKAILLAVLPMSLLSVGKAVDASIFLILTTTGHYSLFPLLFTAPELPIKIILMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVFCEFVFPFTSWNLKYPFIPLLLTSVYCAVGITYAWLKLYVSVLIDPPVGKTKKQ", "length": 526, "header": "tr|A0ABI0NT56-1|A0ABI0NT56_BOVIN Isoform 1 of Alpha-1,3-glucosyltransferase OS=Bos taurus OX=9913 GN=ALG8 PE=3 SV=1 CANONICAL=A0ABI0NT56-1" }, "locus": { "chromosome": "29", "start_pos": 17971854, "end_pos": 17944198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149393.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149393.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107594.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107594.1" } ] } }, { "isoform_ac": "F1MV61-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56/entry#F1MV61-1", "sequence": { "sequence": "MGFSCHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYALSHVAKYFDQEMLNVRNLNYSSSRTLLFQRFSVIFTDALFVYAVHECCKCIDGKKAGKELTEKPKFILSALLLWNFGLLIVDHIHFQYNGFLSGLMLLSIARFFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKQDGSIRWNSFSFVRLISLGLIVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYSAFDKVLSVIGLELKLLDPNKIPKASMTSGLVQQFQHTVLPSVTPLATFICTLIAMLPSVFCLWCKPQGPRGFLRCLILCALSSFMFGWHVHEKAILLAVLPMSLLSVGKAVDASIFLILTTTGHYSLFPLLFTAPELPIKIILMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVFCEFVFPFTSWNLKYPFIPLLLTSVYCAVGITYAWLKLYVSVLIDPPVGKTKKQ", "length": 499, "header": "tr|F1MV61-1|A0ABI0NT56_BOVIN Computationally mapped isoform of Alpha-1,3-glucosyltransferase OS=Bos taurus OX=9913 GN=ALG8 PE=3 SV=2 CANONICAL=A0ABI0NT56-1" }, "locus": { "chromosome": "29", "start_pos": 17971854, "end_pos": 17945750, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000057333.4", "url": "https://www.ensembl.org/id/ENSBTAT00000057333.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049035.2", "url": "https://www.ensembl.org/id/ENSBTAP00000049035.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-446193", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446193", "resource": "Reactome", "description": "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT56", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hexosyltransferase activity", "id": "GO:0016758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016758", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT56", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56" } ], "pmid": "" }, { "name": "dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity", "id": "GO:0042283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042283", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT56", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT56", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-446189", "name": "Addition of a second glucose to the N-glycan precursor by ALG8", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [], "output_participant_list": [ "R-ALL-449638" ], "enzyme_list": [ "A0ABI0NT56-1" ], "evidence": [ { "id": "R-BTA-446189", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446189" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-449638", "participant_name": "(Glc)2 (GlcNAc)2 (Man)9 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]", "crossref": [ { "id": "53020", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0ABI0NT56", "gene_name": "ALG8", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0ABI0NT56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT56" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NMM0-1", "uniprot_ac": "A0ABI0NMM0", "uniprot_id": "A0ABI0NMM0_BOVIN", "mass": { "chemical_mass": 56398.0, "monoisotopic_mass": 56398.0 }, "refseq": { "ac": "NP_001179978", "name": "protein phosphatase 1H", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179978" }, "gene_names": [ { "name": "PPM1H", "type": "recommended", "evidence": [ { "id": "A0ABI0NMM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0" } ] }, { "name": "PPM1H", "type": "synonym", "evidence": [ { "id": "NP_001179978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179978" } ] } ], "protein_names": [ { "name": "Protein phosphatase, Mg2+/Mn2+ dependent 1H", "type": "synonym", "evidence": [ { "id": "A0ABI0NMM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1H (PP2C domain containing)", "type": "synonym", "evidence": [ { "id": "NP_001179978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179978" } ] }, { "name": "protein phosphatase 1H", "type": "synonym", "evidence": [ { "id": "NP_001179978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179978" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMM0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PPM1H", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0", "locus": { "chromosome": "5", "start_pos": 50951595, "end_pos": 50634662, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011857", "url": "https://www.ensembl.org/id/ENSBTAG00000011857" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011857", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011857", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614880", "url": "https://www.ncbi.nlm.nih.gov/gene/614880", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614880", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614880", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1MFZ6", "url": "https://www.orthodb.org/?gene=F1MFZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832:SF287", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832:SF287", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179978", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S2T2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2T2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2T2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7P9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7P9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7P9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9M1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9M1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCB1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCB1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TK66", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TK66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TK66-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TK66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMM0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMM0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MFZ6", "url": "https://www.uniprot.org/uniprotkb/F1MFZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MFZ6-1", "url": "https://www.uniprot.org/uniprotkb/F1MFZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTRVKSAVANFMGGIMAGSSGSEHGSGGCGGSDLPLRFPYGRPEFLGLSQDEVECSADHIARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAITSTPNRNSAKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVEILKNSAVLPPACLGEEPDHTPSSSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSLYNISGGCTALTVVCLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDDDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRVYDLSKYEHGADDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPLIHGNKLS", "length": 514, "header": "tr|A0ABI0NMM0-1|A0ABI0NMM0_BOVIN Isoform 1 of Protein phosphatase, Mg2+/Mn2+ dependent 1H OS=Bos taurus OX=9913 GN=PPM1H PE=4 SV=1 CANONICAL=A0ABI0NMM0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S2T2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0/entry#A0AAA9S2T2-1", "sequence": { "sequence": "MLTRVKSAVANFMGGIMAGSSGSEHGSGGCGGSDLPLRFPYGRPEFLGLSQDEVECSADHIARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAITSTPNRNSAKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVEILKNSAVLPPACLGEEPDHTPSSSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSLYNISGGCTALTVVCLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLDFSGGNVEVDCHFLLQGIFTTQESNPRLLRCRRILCCAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDDDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRVYDLSKYEHGADDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPLIHGNKLS", "length": 551, "header": "tr|A0AAA9S2T2-1|A0ABI0NMM0_BOVIN Computationally mapped isoform of Protein phosphatase, Mg2+/Mn2+ dependent 1H OS=Bos taurus OX=9913 GN=PPM1H PE=4 SV=1 CANONICAL=A0ABI0NMM0-1" }, "locus": { "chromosome": "5", "start_pos": 50937620, "end_pos": 50634861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093607.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093607.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078038.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078038.1" } ] } }, { "isoform_ac": "A0AAA9S7P9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0/entry#A0AAA9S7P9-1", "sequence": { "sequence": "MLTRVKSAVANFMGGIMAGSSGSEHGSGGCGGSDLPLRFPYGRPEFLGLSQDEVECSADHIARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAITSTPNRNSAKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVEILKNSAVLPPACLGEEPDHTPSSSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSLYNISGGCTALTVVCLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDDDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRVYDLSKYEHGADDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISLGQPLSGGHWQKTPQPTQLPTFLRVNSAALECWGSRLRRWTRPSSRSGSSHPRVLPVSTNQLALGAFLGRSNGNTKFCRTYLYVVLLS", "length": 589, "header": "tr|A0AAA9S7P9-1|A0ABI0NMM0_BOVIN Computationally mapped isoform of Protein phosphatase, Mg2+/Mn2+ dependent 1H OS=Bos taurus OX=9913 GN=PPM1H PE=4 SV=1 CANONICAL=A0ABI0NMM0-1" }, "locus": { "chromosome": "5", "start_pos": 50940277, "end_pos": 50634861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120404.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120404.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081264.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081264.1" } ] } }, { "isoform_ac": "A0AAA9T9M1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0/entry#A0AAA9T9M1-1", "sequence": { "sequence": "MLTRVKSAVANFMGGIMAGSSGSEHGSGGCGGSDLPLRFPYGRPEFLGLSQDEVECSADHIARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAITSTPNRNSAKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVEILKNSAVLPPACLGEEPDHTPSSSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSLYNISGGCTALTVVCLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDDDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRVYDLSKYEHGADDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHSHS", "length": 468, "header": "tr|A0AAA9T9M1-1|A0ABI0NMM0_BOVIN Computationally mapped isoform of Protein phosphatase, Mg2+/Mn2+ dependent 1H OS=Bos taurus OX=9913 GN=PPM1H PE=4 SV=1 CANONICAL=A0ABI0NMM0-1" }, "locus": { "chromosome": "5", "start_pos": 50927821, "end_pos": 50634861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099423.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099423.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092597.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092597.1" } ] } }, { "isoform_ac": "A0AAA9TCB1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0/entry#A0AAA9TCB1-1", "sequence": { "sequence": "MLTRVKSAVANFMGGIMAGSSGSEHGSGGCGGSDLPLRFPYGRPEFLGLSQDEVECSADHIARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAITSTPNRNSAKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVEILKNSAVLPPACLGEEPDHTPSSSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSLYNISGGCTALTVVCLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDDDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRVYDLSKYEHGADDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHR", "length": 466, "header": "tr|A0AAA9TCB1-1|A0ABI0NMM0_BOVIN Computationally mapped isoform of Protein phosphatase, Mg2+/Mn2+ dependent 1H OS=Bos taurus OX=9913 GN=PPM1H PE=4 SV=1 CANONICAL=A0ABI0NMM0-1" }, "locus": { "chromosome": "5", "start_pos": 50950639, "end_pos": 50634861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089645.2", "url": "https://www.ensembl.org/id/ENSBTAT00000089645.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096303.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096303.1" } ] } }, { "isoform_ac": "A0AAA9TK66-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0/entry#A0AAA9TK66-1", "sequence": { "sequence": "MLTRVKSAVANFMGGIMAGSSGSEHGSGGCGGSDLPLRFPYGRPEFLGLSQDEVECSADHIARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAITSTPNRNSAKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVEILKNSAVLPPACLGEEPDHTPSSSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSLYNISGGCTALTVVCLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDDDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRVYDLSKYEHGADDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISLGQPLSGGHWQKTPQPTQLPTFLRVNSAALECWGSRLRRWTRPSSQQTWDFPGPC", "length": 556, "header": "tr|A0AAA9TK66-1|A0ABI0NMM0_BOVIN Computationally mapped isoform of Protein phosphatase, Mg2+/Mn2+ dependent 1H OS=Bos taurus OX=9913 GN=PPM1H PE=4 SV=1 CANONICAL=A0ABI0NMM0-1" }, "locus": { "chromosome": "5", "start_pos": 50938251, "end_pos": 50634861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127388.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127388.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097315.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097315.1" } ] } }, { "isoform_ac": "A0ABI0NMM0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0/entry#A0ABI0NMM0-1", "sequence": { "sequence": "MLTRVKSAVANFMGGIMAGSSGSEHGSGGCGGSDLPLRFPYGRPEFLGLSQDEVECSADHIARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAITSTPNRNSAKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVEILKNSAVLPPACLGEEPDHTPSSSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSLYNISGGCTALTVVCLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDDDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRVYDLSKYEHGADDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPLIHGNKLS", "length": 514, "header": "tr|A0ABI0NMM0-1|A0ABI0NMM0_BOVIN Isoform 1 of Protein phosphatase, Mg2+/Mn2+ dependent 1H OS=Bos taurus OX=9913 GN=PPM1H PE=4 SV=1 CANONICAL=A0ABI0NMM0-1" }, "locus": { "chromosome": "5", "start_pos": 50937620, "end_pos": 50634861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136096.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136096.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106718.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106718.1" } ] } }, { "isoform_ac": "F1MFZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0/entry#F1MFZ6-1", "sequence": { "sequence": "MQRNSLSQPSIFSVIGRRLIISCVLTRNGLVGLITAIRHLERVINAGKSTHNEDQASCEVLTVKKKAGAITSTPNRNSAKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVEILKNSAVLPPACLGEEPDHTPSSSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSLYNISGGCTALTVVCLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDDDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRVYDLSKYEHGADDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPLIHGNKLS", "length": 474, "header": "tr|F1MFZ6-1|A0ABI0NMM0_BOVIN Computationally mapped isoform of Protein phosphatase, Mg2+/Mn2+ dependent 1H OS=Bos taurus OX=9913 GN=PPM1H PE=4 SV=3 CANONICAL=A0ABI0NMM0-1" }, "locus": { "chromosome": "5", "start_pos": 50937620, "end_pos": 50737081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015736.8", "url": "https://www.ensembl.org/id/ENSBTAT00000015736.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015736.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015736.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 224, "start_aa": "Thr", "end_pos": 224, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr224", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:614880", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614880", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMM0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMM0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0" } ], "pmid": "" }, { "name": "[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity", "id": "GO:0004741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004741", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMM0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMM0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMM0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMM0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMM0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NMM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMM0" }, { "id": "PS51746", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPM-type phosphatase", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 507, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 224 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 }, { "start_pos": 354, "end_pos": 356 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NMX8-1", "uniprot_ac": "A0ABI0NMX8", "uniprot_id": "A0ABI0NMX8_BOVIN", "mass": { "chemical_mass": 81274.0, "monoisotopic_mass": 81274.0 }, "refseq": {}, "gene_names": [ { "name": "RUFY2", "type": "recommended", "evidence": [ { "id": "A0ABI0NMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8" } ] } ], "protein_names": [ { "name": "RUN and FYVE domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0ABI0NMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMX8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RUFY2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8", "locus": { "chromosome": "28", "start_pos": 24759463, "end_pos": 24807649, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002614", "url": "https://www.ensembl.org/id/ENSBTAG00000002614" } ] } } ], "crossref": [ { "id": "ENSBTAG00000002614", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002614", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15721", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15721", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15759", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15759", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17695", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17695", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539779", "url": "https://www.ncbi.nlm.nih.gov/gene/539779", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IRHDECI", "url": "https://omabrowser.org/oma/group/IRHDECI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LIR8", "url": "https://www.orthodb.org/?gene=A0A3Q1LIR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MEX1", "url": "https://www.orthodb.org/?gene=A0A3Q1MEX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BMQ2", "url": "https://www.orthodb.org/?gene=E1BMQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MEH0", "url": "https://www.orthodb.org/?gene=F1MEH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45956", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45956", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45956:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45956:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LIR8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LIR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MEX1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MEX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S545", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S545", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S545-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S545-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZR6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZR6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4X1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4X1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1Q3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMX8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMX8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMQ2", "url": "https://www.uniprot.org/uniprotkb/E1BMQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMQ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BMQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MEH0", "url": "https://www.uniprot.org/uniprotkb/F1MEH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MEH0-1", "url": "https://www.uniprot.org/uniprotkb/F1MEH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRDQSPPSGSTTRGLPHAPSSGPAGRGEAQRGRISPRPAAGSRVPRPTRAPQNHLGVLPPPGALWAAAGLVADAVAAAARPKGAAGGAQGVPARDCIDTAAMATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSHNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIETYQKLQGSEDGLKEKNEIIARLEEKTSKITAAMKQLEQRLQQAEKAQMEIEDEDKKYLQEYQSKFDSLQKQISQKEKQLAQLETDLKIEKEWRQTLREDLQKEKDTVSHLRNETQQIITLKKEFLNLQDENQRLKKIYHKQEQALQELGNKLSESKLKIEYMKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRPPIPEPPIPEPPPGVEFKKSSMYRCSFE", "length": 717, "header": "tr|A0ABI0NMX8-1|A0ABI0NMX8_BOVIN Isoform 1 of RUN and FYVE domain-containing protein 2 OS=Bos taurus OX=9913 GN=RUFY2 PE=4 SV=1 CANONICAL=A0ABI0NMX8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LIR8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8/entry#A0A3Q1LIR8-1", "sequence": { "sequence": "MATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSHNKTIWGPLELVEKLYPEAEEIGASVRDLPGLNEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIETYQKLQGSEDGLKEKNEIIARLEEKTSKITAAMKQLEQSDNDLLTQTRTIAMSLVKCASSDTQDQYKLVKDISF", "length": 403, "header": "tr|A0A3Q1LIR8-1|A0ABI0NMX8_BOVIN Computationally mapped isoform of RUN and FYVE domain-containing protein 2 OS=Bos taurus OX=9913 GN=RUFY2 PE=4 SV=2 CANONICAL=A0ABI0NMX8-1" }, "locus": { "chromosome": "28", "start_pos": 24807147, "end_pos": 24786558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075929.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075929.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059032.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059032.2" } ] } }, { "isoform_ac": "A0A3Q1MEX1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8/entry#A0A3Q1MEX1-1", "sequence": { "sequence": "MRDQSPPSGSTTRGLPHAPSSGPAGRGEAQRGRISPRPAAGSRVPRPTRAPQNHLGVLPPPGALWAAAGLVADAVAAAARPKGAAGGAQGVPARDCIDTAAMATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSHNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIETYQKLQGSEDGLKEKNEIIARLEEKTSKITAAMKQLEQRLQQAEKAQMEIEDEDKKYLQEYQSKFDSLQKQISQKEKQLAQLETDLKIEKEWRQTLREDLQKEKDTVSHLRNETQQIITLKKEFLNLQDENQRLKKIYHKQEQALQELGNKLSESKLKIEYMKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKTWQLLHLHVSQTLHLLLLLLCHQLQYQYVLGLDLVVRRTKENTYFTF", "length": 707, "header": "tr|A0A3Q1MEX1-1|A0ABI0NMX8_BOVIN Computationally mapped isoform of RUN and FYVE domain-containing protein 2 OS=Bos taurus OX=9913 GN=RUFY2 PE=4 SV=2 CANONICAL=A0ABI0NMX8-1" }, "locus": { "chromosome": "28", "start_pos": 24807450, "end_pos": 24759485, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071619.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071619.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067447.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067447.2" } ] } }, { "isoform_ac": "A0AAA9S545-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8/entry#A0AAA9S545-1", "sequence": { "sequence": "MRDQSPPSGSTTRGLPHAPSSGPAGRGEAQRGRISPRPAAGSRVPRPTRAPQNHLGVLPPPGALWAAAGLVADAVAAAARPKGAAGGAQGVPARDCIDTAAMATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSHNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIETYQKLQGSEDGLKEKNEIIARLEEKTSKITAAMKQLEQRLQQAEKAQMEIEDEDKKYLQEYQSKFDSLQKQISQKEKQLAQLETDLKIEKEWRQTLREDLQKEKDTVSHLRNETQQIITLKKEFLNLQDENQRLKKIYHKQEQALQELGNKLSESKLKIEYMKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSSNLP", "length": 707, "header": "tr|A0AAA9S545-1|A0ABI0NMX8_BOVIN Computationally mapped isoform of RUN and FYVE domain-containing protein 2 OS=Bos taurus OX=9913 GN=RUFY2 PE=4 SV=1 CANONICAL=A0ABI0NMX8-1" }, "locus": { "chromosome": "28", "start_pos": 24807450, "end_pos": 24764876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118113.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118113.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078352.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078352.1" } ] } }, { "isoform_ac": "A0AAA9SZR6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8/entry#A0AAA9SZR6-1", "sequence": { "sequence": "MRDQSPPSGSTTRGLPHAPSSGPAGRGEAQRGRISPRPAAGSRVPRPTRAPQNHLGVLPPPGALWAAAGLVADAVAAAARPKGAAGGAQGVPARDCIDTAAMATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSHNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIETYQKLQGSEDGLKEKNEIIARLEEKTSKITAAMKQLEQRLQQAEKAQMEIEDEDKKYLQEYQSKFDSLQKQISQKEKQLAQLETDLKIEKEWRQTLREDLQKEKDTVSHLRNETQQIITLKKEFLNLQDENQRLKKIYHKQEQALQELGNKLSESKLKIEYMKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSSNLP", "length": 668, "header": "tr|A0AAA9SZR6-1|A0ABI0NMX8_BOVIN Computationally mapped isoform of RUN and FYVE domain-containing protein 2 OS=Bos taurus OX=9913 GN=RUFY2 PE=4 SV=1 CANONICAL=A0ABI0NMX8-1" }, "locus": { "chromosome": "28", "start_pos": 24807450, "end_pos": 24764876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090470.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090470.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091967.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091967.1" } ] } }, { "isoform_ac": "A0AAA9T4X1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8/entry#A0AAA9T4X1-1", "sequence": { "sequence": "MRDQSPPSGSTTRGLPHAPSSGPAGRGEAQRGRISPRPAAGSRVPRPTRAPQNHLGVLPPPGALWAAAGLVADAVAAAARPKGAAGGAQGVPARDCIDTAAMVRKSFLSHNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIETYQKLQGSEDGLKEKNEIIARLEEKTSKITAAMKQLEQSDNDLLTQTRTIAMSLVKCASSDTQDQYKLVKDISF", "length": 480, "header": "tr|A0AAA9T4X1-1|A0ABI0NMX8_BOVIN Computationally mapped isoform of RUN and FYVE domain-containing protein 2 OS=Bos taurus OX=9913 GN=RUFY2 PE=4 SV=2 CANONICAL=A0ABI0NMX8-1" }, "locus": { "chromosome": "28", "start_pos": 24807450, "end_pos": 24786558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105312.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105312.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092867.2", "url": "https://www.ensembl.org/id/ENSBTAP00000092867.2" } ] } }, { "isoform_ac": "A0AAA9U1Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8/entry#A0AAA9U1Q3-1", "sequence": { "sequence": "MRDQSPPSGSTTRGLPHAPSSGPAGRGEAQRGRISPRPAAGSRVPRPTRAPQNHLGVLPPPGALWAAAGLVADAVAAAARPKGAAGGAQGVPARDCIDTAAMATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSHNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIETYQKLQGSEDGLKEKNEIIARLEEKTSKITAAMKQLEQRLQQAEKAQMEIEDEDKKYLQEYQSKFDSLQKQISQKEKQLAQLETDLKIEKEWRQTLREDLQKEKDTVSHLRNETQQIITLKKEFLNLQDENQRLKKIYHKQEQALQELGNKLSEVPWTARRSNQSILKEISPRCSLERLMLKLKLQYLGHLMRRADSFEKTLMLGKI", "length": 671, "header": "tr|A0AAA9U1Q3-1|A0ABI0NMX8_BOVIN Computationally mapped isoform of RUN and FYVE domain-containing protein 2 OS=Bos taurus OX=9913 GN=RUFY2 PE=4 SV=1 CANONICAL=A0ABI0NMX8-1" }, "locus": { "chromosome": "28", "start_pos": 24807450, "end_pos": 24775241, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119450.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119450.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103783.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103783.1" } ] } }, { "isoform_ac": "A0ABI0NMX8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8/entry#A0ABI0NMX8-1", "sequence": { "sequence": "MRDQSPPSGSTTRGLPHAPSSGPAGRGEAQRGRISPRPAAGSRVPRPTRAPQNHLGVLPPPGALWAAAGLVADAVAAAARPKGAAGGAQGVPARDCIDTAAMATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSHNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIETYQKLQGSEDGLKEKNEIIARLEEKTSKITAAMKQLEQRLQQAEKAQMEIEDEDKKYLQEYQSKFDSLQKQISQKEKQLAQLETDLKIEKEWRQTLREDLQKEKDTVSHLRNETQQIITLKKEFLNLQDENQRLKKIYHKQEQALQELGNKLSESKLKIEYMKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRPPIPEPPIPEPPPGVEFKKSSMYRCSFE", "length": 717, "header": "tr|A0ABI0NMX8-1|A0ABI0NMX8_BOVIN Isoform 1 of RUN and FYVE domain-containing protein 2 OS=Bos taurus OX=9913 GN=RUFY2 PE=4 SV=1 CANONICAL=A0ABI0NMX8-1" }, "locus": { "chromosome": "28", "start_pos": 24807450, "end_pos": 24760619, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136280.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136280.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104075.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104075.1" } ] } }, { "isoform_ac": "E1BMQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8/entry#E1BMQ2-1", "sequence": { "sequence": "MRDQSPPSGSTTRGLPHAPSSGPAGRGEAQRGRISPRPAAGSRVPRPTRAPQNHLGVLPPPGALWAAAGLVADAVAAAARPKGAAGGAQGVPARDCIDTAAMVRKSFLSHNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIETYQKLQGSEDGLKEKNEIIARLEEKTSKITAAMKQLEQRLQQAEKAQMEIEDEDKKYLQEYQSKFDSLQKQISQKEKQLAQLETDLKIEKEWRQTLREDLQKEKDTVSHLRNETQQIITLKKEFLNLQDENQRLKKIYHKQEQALQELGNKLSESKLKIEYMKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSSNLP", "length": 649, "header": "tr|E1BMQ2-1|A0ABI0NMX8_BOVIN Computationally mapped isoform of RUN and FYVE domain-containing protein 2 OS=Bos taurus OX=9913 GN=RUFY2 PE=4 SV=3 CANONICAL=A0ABI0NMX8-1" }, "locus": { "chromosome": "28", "start_pos": 24807450, "end_pos": 24764876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003382.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003382.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003382.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003382.6" } ] } }, { "isoform_ac": "F1MEH0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8/entry#F1MEH0-1", "sequence": { "sequence": "MAKVSRLDGLQGASTGPAGVPLQGRGNNRGRAMTFQVWGRRREASHDLAWVPDAEGGRGTAMRHRTPATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSHNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIETYQKLQGSEDGLKEKNEIIARLEEKTSKITAAMKQLEQRLQQAEKAQMEIEDEDKKYLQEYQSKFDSLQKQISQKEKQLAQLETDLKIEKEWRQTLREDLQKEKDTVSHLRNETQQIITLKKEFLNLQDENQRLKKIYHKQEQALQELGNKLSESKLKIEYMKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSSNLP", "length": 672, "header": "tr|F1MEH0-1|A0ABI0NMX8_BOVIN Computationally mapped isoform of RUN and FYVE domain-containing protein 2 OS=Bos taurus OX=9913 GN=RUFY2 PE=4 SV=3 CANONICAL=A0ABI0NMX8-1" }, "locus": { "chromosome": "28", "start_pos": 24806911, "end_pos": 24764876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054280.4", "url": "https://www.ensembl.org/id/ENSBTAT00000054280.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048103.3", "url": "https://www.ensembl.org/id/ENSBTAP00000048103.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4LHR8-1", "protein_name": "RUN and FYVE domain-containing protein 2", "gene_name": "CG14261", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRGLVEDTKRTKLSSANNNNLSSTSGSGRIKSSSLATGSSASGSSSKPLRSAVKTPTSGSATSLSSGTMAAKKAPQTGQQQVGKSAKSATAATPTGTTATAIGATATTRAQAAAAKSQKGQNPPSQQVQPKQQPPQPQQTQQQPLVLQQQQASNSSNTIALPKASHANTSEELAGGVQDTIYLCNFRVSVDGEWLCLKELQDIDVAGGTGNQAAQTSEKLAGGSSSQTGGFGSNYNVGSSSSKRNSKRFSGLSTGSGSGGNAGGGGGLDITDNARDTAEIERSNLVNICKLVVKELLEQSLRYGRMLDSDHLPLQHFFIVIEHVLGHGLRPKKGLLGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALMQKKLSDYLQALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCNLCVKEEDLDSQQGVIDFSLYLRSSSRNADAAPEDSAPPALLDATGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQAENQAMRQSTSAGDNNSTGSGGSSDKDKEKASEELVEERRKNSELEKELKLQVSLKAESDMAMKLLEKDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQDCKASLTHKTELMTKLEVQKEDMASTIDQLEKKWSHDKSNLGEILKTTSQTLTTQVTASEERAARAEAESRIEREWRISLQEKELKLKEKIANLQGCLKELSEEKERNGKLKADLDKVRTQWSEAQTTLEELGIQLSVSKLKVSEMQDQERRQRQLLSGSAQSLQAMPEAVGSPGIWAPDSIATHCTACEREFNLTRRKHHCRSCGEIFCKACSEHTLPLLNAQGQPGKPVRVCDNCYAAK", "length": 877 }, "evidence": [ { "id": "A0ABI0NMX8", "url": "https://omabrowser.org/oma/group/A0ABI0NMX8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A0G2K4D6-1", "protein_name": "RUN and FYVE domain containing 2", "gene_name": "Rufy2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSREWWAEDWGEERCGIRSREPVPRGLRAGWGTERAGPPLGTAGECWRLAPPTTAAAQAAVLGCRLQVVMNTLKKGILPIMKRQVVWARGWVEESHLDGEWRKKMWADPGCFRLRRMSAYLAEMQTITEATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRELLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEEIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENELILMRTRQHLEVTKVDVETELQTYKHSRQGLDEMYDDARRQLRDESQLRQDVENELSVQVGMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLEEKTNKITTAMRQLEQRLQQAEKAQMEAEDEDEKYAQECLSKSDSLQRQISQKEQQLVQLETDLKIEKEWRQTLQEDLQKEKDVLSHLRHETQKIISLKKEFLNLQDENQQLKRIYHEQEQALQELGSKLCESKLKIDDIKEANKALQGLVWLKDKDATHCKLCEKEFSLSKRKTWQPLHLHVSQTLHLPLLLLCHRLQYQYERVLD", "length": 723 }, "evidence": [ { "id": "A0ABI0NMX8", "url": "https://omabrowser.org/oma/group/A0ABI0NMX8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A4X1TNR4-1", "protein_name": "RUN and FYVE domain containing 2", "gene_name": "RUFY2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRDIKRTTKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLEEKTSKITAAMRQLEQRLQQAEKAQMDTEDEDKKCLQECQSKFDSLQKQISQKEKQLVQLETDLKIEKEWRQTLQEDLQKEKDTLSHLRNETQQIISLKKEFLNLQDENQQLKKIYHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSSNLP", "length": 594 }, "evidence": [ { "id": "A0ABI0NMX8", "url": "https://omabrowser.org/oma/group/A0ABI0NMX8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZYI0-1", "protein_name": "RUN and FYVE domain-containing protein 2", "gene_name": "RUFY2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKLYPEAEEIAASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRELLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKSDDDIGGKERNEQIAAILDQKNYVEELNRQLNSTVSSLHARVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENTLILMKTQHHLEVTKVDVEAELQTYKHSRQGLDEMYNEARRQLREESQLRQDMENELVVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLDEVKAINMEMYQKLQVSDDAMKEKNEIIGRLEDKTNQINATMKQLEQRLQQAEKAQLDAENEDKKLKQEYVNKSESLQKEFSQKEKQLLQLETDLKIEKEWRQTLQDDLQKEKETVSHLRIETQEIINLKKEFIKLQEKNRQLKRICQDQEAALQELASKLSESKLKIEDIKEANKALQGQVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHAILIQRCSSNVP", "length": 606 }, "evidence": [ { "id": "A0ABI0NMX8", "url": "https://omabrowser.org/oma/group/A0ABI0NMX8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8R4C2-1", "protein_name": "RUN and FYVE domain-containing protein 2", "gene_name": "Rufy2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKGRKSFLSYNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRELLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEEIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENELILMRTRQHLEVTKVDVETELQTYKHSRQGLDEMYNDARRQLRDESQLRQDVENELSVQVGMKHEMELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQRLQGSEDGLKEKNEIIARLEEKTNKITTAMRQLEQRLQQAEKAQKEAEAEDEKYAQECLSQSDSLQRQISQKEQQLVQLETDLKIEKEWRQTLQEDLQKEKDVLSHLRHETQKVISLKKEFLNLQDENQQLKRIYQEQEQALQELGSKLCESKLKIDDIKEANKALQGLVWLKDKDATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHAMLIQRCSSNMP", "length": 606 }, "evidence": [ { "id": "A0ABI0NMX8", "url": "https://omabrowser.org/oma/group/A0ABI0NMX8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WXA3-2", "protein_name": "RUN and FYVE domain-containing protein 2", "gene_name": "RUFY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQKEKQLVQLETDLKIEKEWRQTLQEDLQKEKDALSHLRNETQQIISLKKEFLNLQDENQQLKKIYHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSSNLP", "length": 606 }, "evidence": [ { "id": "A0ABI0NMX8", "url": "https://omabrowser.org/oma/group/A0ABI0NMX8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMX8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMX8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMX8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 641, "end_pos": 689, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMX8" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 270, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 576, "end_pos": 578 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] } ]